LOCUS       DBBGSZ010000001       148599 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.001, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000001 DBBGSZ010000000
VERSION     DBBGSZ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 148599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 148599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..148599
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.001"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(530..2026)
                     /gene="lysS"
                     /locus_tag="ACIZE5_000001"
     CDS             complement(530..2026)
                     /gene="lysS"
                     /locus_tag="ACIZE5_000001"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HGC6107193.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="ACIZE5_000002"
     CDS             complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="ACIZE5_000002"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HGC6107194.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="ACIZE5_000003"
     CDS             complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="ACIZE5_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HGC6107195.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4246..6357)
                     /gene="ftsH"
                     /locus_tag="ACIZE5_000004"
     CDS             complement(4246..6357)
                     /gene="ftsH"
                     /locus_tag="ACIZE5_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HGC6107196.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="ACIZE5_000005"
     CDS             complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="ACIZE5_000005"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HGC6107197.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="ACIZE5_000006"
     CDS             complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="ACIZE5_000006"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HGC6107198.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8557..9027)
                     /locus_tag="ACIZE5_000007"
     CDS             complement(8557..9027)
                     /locus_tag="ACIZE5_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 domain-containing RNA-binding protein"
                     /protein_id="HGC6107199.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9073..9498)
                     /locus_tag="ACIZE5_000008"
     CDS             complement(9073..9498)
                     /locus_tag="ACIZE5_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HGC6107200.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9565..9834)
                     /locus_tag="ACIZE5_000009"
     CDS             complement(9565..9834)
                     /locus_tag="ACIZE5_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HGC6107201.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9845..11440)
                     /locus_tag="ACIZE5_000010"
     CDS             complement(9845..11440)
                     /locus_tag="ACIZE5_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGC6107202.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="ACIZE5_000011"
     CDS             complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="ACIZE5_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HGC6107203.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14993..15553)
                     /gene="pth"
                     /locus_tag="ACIZE5_000012"
     CDS             complement(14993..15553)
                     /gene="pth"
                     /locus_tag="ACIZE5_000012"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HGC6107204.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15906..16880
                     /locus_tag="ACIZE5_000013"
     CDS             15906..16880
                     /locus_tag="ACIZE5_000013"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HGC6107205.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            17050..18450
                     /locus_tag="ACIZE5_000014"
     CDS             17050..18450
                     /locus_tag="ACIZE5_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HGC6107206.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18528..19250)
                     /locus_tag="ACIZE5_000015"
     CDS             complement(18528..19250)
                     /locus_tag="ACIZE5_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6107207.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19329..19835)
                     /locus_tag="ACIZE5_000016"
     CDS             complement(19329..19835)
                     /locus_tag="ACIZE5_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGC6107208.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19958..21757
                     /locus_tag="ACIZE5_000017"
     CDS             19958..21757
                     /locus_tag="ACIZE5_000017"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HGC6107209.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21825..23399)
                     /locus_tag="ACIZE5_000018"
     CDS             complement(21825..23399)
                     /locus_tag="ACIZE5_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HGC6107210.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23654..24163)
                     /gene="mreD"
                     /locus_tag="ACIZE5_000019"
     CDS             complement(23654..24163)
                     /gene="mreD"
                     /locus_tag="ACIZE5_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HGC6107211.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(24167..25021)
                     /gene="mreC"
                     /locus_tag="ACIZE5_000020"
     CDS             complement(24167..25021)
                     /gene="mreC"
                     /locus_tag="ACIZE5_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HGC6107212.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(25176..25814)
                     /locus_tag="ACIZE5_000021"
     CDS             complement(25176..25814)
                     /locus_tag="ACIZE5_000021"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HGC6107213.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25815..26465)
                     /gene="rpe"
                     /locus_tag="ACIZE5_000022"
     CDS             complement(25815..26465)
                     /gene="rpe"
                     /locus_tag="ACIZE5_000022"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGC6107214.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(26478..27377)
                     /gene="rsgA"
                     /locus_tag="ACIZE5_000023"
     CDS             complement(26478..27377)
                     /gene="rsgA"
                     /locus_tag="ACIZE5_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HGC6107215.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27542..29611)
                     /gene="pknB"
                     /locus_tag="ACIZE5_000024"
     CDS             complement(27542..29611)
                     /gene="pknB"
                     /locus_tag="ACIZE5_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HGC6107216.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29608..30348)
                     /locus_tag="ACIZE5_000025"
     CDS             complement(29608..30348)
                     /locus_tag="ACIZE5_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HGC6107217.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(30361..31719)
                     /gene="rsmB"
                     /locus_tag="ACIZE5_000026"
     CDS             complement(30361..31719)
                     /gene="rsmB"
                     /locus_tag="ACIZE5_000026"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HGC6107218.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31719..32657)
                     /gene="fmt"
                     /locus_tag="ACIZE5_000027"
     CDS             complement(31719..32657)
                     /gene="fmt"
                     /locus_tag="ACIZE5_000027"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HGC6107219.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32650..33141)
                     /gene="def"
                     /locus_tag="ACIZE5_000028"
     CDS             complement(32650..33141)
                     /gene="def"
                     /locus_tag="ACIZE5_000028"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGC6107220.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(33156..35564)
                     /gene="priA"
                     /locus_tag="ACIZE5_000029"
     CDS             complement(33156..35564)
                     /gene="priA"
                     /locus_tag="ACIZE5_000029"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HGC6107221.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35817..36122)
                     /gene="rpoZ"
                     /locus_tag="ACIZE5_000030"
     CDS             complement(35817..36122)
                     /gene="rpoZ"
                     /locus_tag="ACIZE5_000030"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGC6107222.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(36127..36741)
                     /gene="gmk"
                     /locus_tag="ACIZE5_000031"
     CDS             complement(36127..36741)
                     /gene="gmk"
                     /locus_tag="ACIZE5_000031"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HGC6107223.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(37228..37512)
                     /locus_tag="ACIZE5_000032"
     CDS             complement(37228..37512)
                     /locus_tag="ACIZE5_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107224.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37530..38420)
                     /locus_tag="ACIZE5_000033"
     CDS             complement(37530..38420)
                     /locus_tag="ACIZE5_000033"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HGC6107225.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(38440..38658)
                     /locus_tag="ACIZE5_000034"
     CDS             complement(38440..38658)
                     /locus_tag="ACIZE5_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HGC6107226.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38628..40328)
                     /locus_tag="ACIZE5_000035"
     CDS             complement(38628..40328)
                     /locus_tag="ACIZE5_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HGC6107227.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40595..41368
                     /locus_tag="ACIZE5_000036"
     CDS             40595..41368
                     /locus_tag="ACIZE5_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107228.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(41449..42018)
                     /gene="thiT"
                     /locus_tag="ACIZE5_000037"
     CDS             complement(41449..42018)
                     /gene="thiT"
                     /locus_tag="ACIZE5_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015234 - thiamine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HGC6107229.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(42084..42186)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(42192..43163)
                     /locus_tag="ACIZE5_000038"
     CDS             complement(42192..43163)
                     /locus_tag="ACIZE5_000038"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGC6107230.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(43257..44630)
                     /gene="glmU"
                     /locus_tag="ACIZE5_000039"
     CDS             complement(43257..44630)
                     /gene="glmU"
                     /locus_tag="ACIZE5_000039"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HGC6107231.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(45133..45951)
                     /gene="purR"
                     /locus_tag="ACIZE5_000040"
     CDS             complement(45133..45951)
                     /gene="purR"
                     /locus_tag="ACIZE5_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HGC6107232.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(46118..46942)
                     /locus_tag="ACIZE5_000041"
     CDS             complement(46118..46942)
                     /locus_tag="ACIZE5_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HGC6107233.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(46915..47595)
                     /locus_tag="ACIZE5_000042"
     CDS             complement(46915..47595)
                     /locus_tag="ACIZE5_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGC6107234.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47618..48556)
                     /locus_tag="ACIZE5_000043"
     CDS             complement(47618..48556)
                     /locus_tag="ACIZE5_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HGC6107235.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(48801..49652)
                     /gene="ispE"
                     /locus_tag="ACIZE5_000044"
     CDS             complement(48801..49652)
                     /gene="ispE"
                     /locus_tag="ACIZE5_000044"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HGC6107236.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(49806..52379)
                     /gene="mprF"
                     /locus_tag="ACIZE5_000045"
     CDS             complement(49806..52379)
                     /gene="mprF"
                     /locus_tag="ACIZE5_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HGC6107237.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSHMTILLMILAGMLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFSEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            52520..53326
                     /gene="proC"
                     /locus_tag="ACIZE5_000046"
     CDS             52520..53326
                     /gene="proC"
                     /locus_tag="ACIZE5_000046"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HGC6107238.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAVIKGINTTIEKDLEMLNKK"
     gene            complement(53405..54961)
                     /gene="rny"
                     /locus_tag="ACIZE5_000047"
     CDS             complement(53405..54961)
                     /gene="rny"
                     /locus_tag="ACIZE5_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HGC6107239.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDIIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(55372..56418)
                     /gene="recA"
                     /locus_tag="ACIZE5_000048"
     CDS             complement(55372..56418)
                     /gene="recA"
                     /locus_tag="ACIZE5_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HGC6107240.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLEE"
     gene            complement(56527..57768)
                     /locus_tag="ACIZE5_000049"
     CDS             complement(56527..57768)
                     /locus_tag="ACIZE5_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HGC6107241.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLVY
                     FETTHRKMTKNNLQQSQIIEGGIPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(58008..58586)
                     /gene="pgsA"
                     /locus_tag="ACIZE5_000050"
     CDS             complement(58008..58586)
                     /gene="pgsA"
                     /locus_tag="ACIZE5_000050"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HGC6107242.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQLNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(58795..59718)
                     /locus_tag="ACIZE5_000051"
     CDS             complement(58795..59718)
                     /locus_tag="ACIZE5_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RodZ domain-containing protein"
                     /protein_id="HGC6107243.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(60457..61743)
                     /locus_tag="ACIZE5_000052"
     CDS             complement(60457..61743)
                     /locus_tag="ACIZE5_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGC6107244.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(61736..63004)
                     /locus_tag="ACIZE5_000053"
     CDS             complement(61736..63004)
                     /locus_tag="ACIZE5_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGC6107245.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            63256..63717
                     /gene="mscL"
                     /locus_tag="ACIZE5_000054"
     CDS             63256..63717
                     /gene="mscL"
                     /locus_tag="ACIZE5_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HGC6107246.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(63776..64222)
                     /locus_tag="ACIZE5_000055"
     CDS             complement(63776..64222)
                     /locus_tag="ACIZE5_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6107247.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(64315..64560)
                     /locus_tag="ACIZE5_000056"
     CDS             complement(64315..64560)
                     /locus_tag="ACIZE5_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HGC6107248.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(64675..65253)
                     /locus_tag="ACIZE5_000057"
     CDS             complement(64675..65253)
                     /locus_tag="ACIZE5_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGC6107249.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(65330..65860)
                     /locus_tag="ACIZE5_000058"
     CDS             complement(65330..65860)
                     /locus_tag="ACIZE5_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HGC6107250.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(65864..66724)
                     /gene="rlmB"
                     /locus_tag="ACIZE5_000059"
     CDS             complement(65864..66724)
                     /gene="rlmB"
                     /locus_tag="ACIZE5_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HGC6107251.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(66717..67112)
                     /locus_tag="ACIZE5_000060"
     CDS             complement(66717..67112)
                     /locus_tag="ACIZE5_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HGC6107252.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(67109..68521)
                     /gene="cysS"
                     /locus_tag="ACIZE5_000061"
     CDS             complement(67109..68521)
                     /gene="cysS"
                     /locus_tag="ACIZE5_000061"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HGC6107253.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(68518..69054)
                     /gene="epsC"
                     /locus_tag="ACIZE5_000062"
     CDS             complement(68518..69054)
                     /gene="epsC"
                     /locus_tag="ACIZE5_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HGC6107254.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(69140..69379)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(69376..70836)
                     /gene="gltX"
                     /locus_tag="ACIZE5_000063"
     CDS             complement(69376..70836)
                     /gene="gltX"
                     /locus_tag="ACIZE5_000063"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HGC6107255.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(71006..72163)
                     /locus_tag="ACIZE5_000064"
     CDS             complement(71006..72163)
                     /locus_tag="ACIZE5_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HGC6107256.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(72197..73567)
                     /gene="radA"
                     /locus_tag="ACIZE5_000065"
     CDS             complement(72197..73567)
                     /gene="radA"
                     /locus_tag="ACIZE5_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HGC6107257.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(73630..74157)
                     /locus_tag="ACIZE5_000066"
     CDS             complement(73630..74157)
                     /locus_tag="ACIZE5_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HGC6107258.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            74387..75193
                     /gene="proB"
                     /locus_tag="ACIZE5_000067"
     CDS             74387..75193
                     /gene="proB"
                     /locus_tag="ACIZE5_000067"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HGC6107259.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            75190..76437
                     /locus_tag="ACIZE5_000068"
     CDS             75190..76437
                     /locus_tag="ACIZE5_000068"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HGC6107260.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            76513..76857
                     /locus_tag="ACIZE5_000069"
     CDS             76513..76857
                     /locus_tag="ACIZE5_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107261.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(76974..77300)
                     /locus_tag="ACIZE5_000070"
     CDS             complement(76974..77300)
                     /locus_tag="ACIZE5_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107262.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(77915..79117)
                     /locus_tag="ACIZE5_000071"
     CDS             complement(77915..79117)
                     /locus_tag="ACIZE5_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6107263.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            79234..79749
                     /locus_tag="ACIZE5_000072"
     CDS             79234..79749
                     /locus_tag="ACIZE5_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGC6107264.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(79948..80394)
                     /locus_tag="ACIZE5_000073"
     CDS             complement(79948..80394)
                     /locus_tag="ACIZE5_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HGC6107265.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(80441..81919)
                     /gene="msr(C)"
                     /locus_tag="ACIZE5_000074"
     CDS             complement(80441..81919)
                     /gene="msr(C)"
                     /locus_tag="ACIZE5_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HGC6107266.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(82273..82902)
                     /locus_tag="ACIZE5_000075"
     CDS             complement(82273..82902)
                     /locus_tag="ACIZE5_000075"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGC6107267.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(82886..83350)
                     /locus_tag="ACIZE5_000076"
     CDS             complement(82886..83350)
                     /locus_tag="ACIZE5_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGC6107268.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(83837..85105)
                     /locus_tag="ACIZE5_000077"
     CDS             complement(83837..85105)
                     /locus_tag="ACIZE5_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HGC6107269.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(85336..86073)
                     /locus_tag="ACIZE5_000078"
     CDS             complement(85336..86073)
                     /locus_tag="ACIZE5_000078"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HGC6107270.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(86140..86709)
                     /locus_tag="ACIZE5_000079"
     CDS             complement(86140..86709)
                     /locus_tag="ACIZE5_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HGC6107271.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            86837..87709
                     /locus_tag="ACIZE5_000080"
     CDS             86837..87709
                     /locus_tag="ACIZE5_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGC6107272.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            88051..88923
                     /locus_tag="ACIZE5_000081"
     CDS             88051..88923
                     /locus_tag="ACIZE5_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGC6107273.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            88920..90878
                     /gene="nagE"
                     /locus_tag="ACIZE5_000082"
     CDS             88920..90878
                     /gene="nagE"
                     /locus_tag="ACIZE5_000082"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HGC6107274.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(91210..92061)
                     /locus_tag="ACIZE5_000083"
     CDS             complement(91210..92061)
                     /locus_tag="ACIZE5_000083"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HGC6107275.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            92184..92651
                     /locus_tag="ACIZE5_000084"
     CDS             92184..92651
                     /locus_tag="ACIZE5_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HGC6107276.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(92914..93396)
                     /locus_tag="ACIZE5_000085"
     CDS             complement(92914..93396)
                     /locus_tag="ACIZE5_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HGC6107277.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(93496..94359)
                     /locus_tag="ACIZE5_000086"
     CDS             complement(93496..94359)
                     /locus_tag="ACIZE5_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HGC6107278.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            94957..95832
                     /locus_tag="ACIZE5_000087"
     CDS             94957..95832
                     /locus_tag="ACIZE5_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HGC6107279.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(95977..96129)
                     /locus_tag="ACIZE5_000088"
                     /pseudo
     CDS             complement(95977..96129)
                     /locus_tag="ACIZE5_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(96397..97728)
                     /locus_tag="ACIZE5_000089"
     CDS             complement(96397..97728)
                     /locus_tag="ACIZE5_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGC6107280.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(97877..98590)
                     /locus_tag="ACIZE5_000090"
     CDS             complement(97877..98590)
                     /locus_tag="ACIZE5_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6107281.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            98765..100189
                     /locus_tag="ACIZE5_000091"
     CDS             98765..100189
                     /locus_tag="ACIZE5_000091"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC6107282.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            100488..101195
                     /locus_tag="ACIZE5_000092"
     CDS             100488..101195
                     /locus_tag="ACIZE5_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HGC6107283.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            101182..101505
                     /locus_tag="ACIZE5_000093"
     CDS             101182..101505
                     /locus_tag="ACIZE5_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HGC6107284.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(101594..102631)
                     /locus_tag="ACIZE5_000094"
     CDS             complement(101594..102631)
                     /locus_tag="ACIZE5_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HGC6107285.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(102952..103935)
                     /locus_tag="ACIZE5_000095"
     CDS             complement(102952..103935)
                     /locus_tag="ACIZE5_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase"
                     /protein_id="HGC6107286.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(104350..105120)
                     /locus_tag="ACIZE5_000096"
     CDS             complement(104350..105120)
                     /locus_tag="ACIZE5_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6107287.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(105113..106048)
                     /locus_tag="ACIZE5_000097"
     CDS             complement(105113..106048)
                     /locus_tag="ACIZE5_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6107288.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(106364..108013)
                     /locus_tag="ACIZE5_000098"
     CDS             complement(106364..108013)
                     /locus_tag="ACIZE5_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HGC6107289.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(108130..110733)
                     /locus_tag="ACIZE5_000099"
     CDS             complement(108130..110733)
                     /locus_tag="ACIZE5_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HGC6107290.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(110745..111794)
                     /locus_tag="ACIZE5_000100"
     CDS             complement(110745..111794)
                     /locus_tag="ACIZE5_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HGC6107291.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(111820..112134)
                     /locus_tag="ACIZE5_000101"
     CDS             complement(111820..112134)
                     /locus_tag="ACIZE5_000101"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HGC6107292.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(112150..112596)
                     /locus_tag="ACIZE5_000102"
     CDS             complement(112150..112596)
                     /locus_tag="ACIZE5_000102"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose PTS transporter subunit IIA"
                     /protein_id="HGC6107293.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(112597..114519)
                     /locus_tag="ACIZE5_000103"
     CDS             complement(112597..114519)
                     /locus_tag="ACIZE5_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGC6107294.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            complement(114731..115627)
                     /locus_tag="ACIZE5_000104"
     CDS             complement(114731..115627)
                     /locus_tag="ACIZE5_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGC6107295.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(115620..116300)
                     /locus_tag="ACIZE5_000105"
     CDS             complement(115620..116300)
                     /locus_tag="ACIZE5_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC6107296.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(116301..117083)
                     /locus_tag="ACIZE5_000106"
     CDS             complement(116301..117083)
                     /locus_tag="ACIZE5_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGC6107297.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(117076..117993)
                     /locus_tag="ACIZE5_000107"
     CDS             complement(117076..117993)
                     /locus_tag="ACIZE5_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGC6107298.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(118157..118411)
                     /locus_tag="ACIZE5_000108"
     CDS             complement(118157..118411)
                     /locus_tag="ACIZE5_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107299.1"
                     /translation="MSTITTITMVASPLGLALFGALFDWKTTQPRLRDSLIFLGGSLA
                     IVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEKKESGN"
     gene            119268..122495
                     /gene="fss3"
                     /locus_tag="ACIZE5_000109"
     CDS             119268..122495
                     /gene="fss3"
                     /locus_tag="ACIZE5_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HGC6107300.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            122608..122922
                     /locus_tag="ACIZE5_000110"
     CDS             122608..122922
                     /locus_tag="ACIZE5_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HGC6107301.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            122935..123309
                     /locus_tag="ACIZE5_000111"
     CDS             122935..123309
                     /locus_tag="ACIZE5_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HGC6107302.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            123319..123654
                     /locus_tag="ACIZE5_000112"
     CDS             123319..123654
                     /locus_tag="ACIZE5_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HGC6107303.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            123737..125077
                     /locus_tag="ACIZE5_000113"
     CDS             123737..125077
                     /locus_tag="ACIZE5_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HGC6107304.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            125155..125829
                     /locus_tag="ACIZE5_000114"
     CDS             125155..125829
                     /locus_tag="ACIZE5_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HGC6107305.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            125822..125986
                     /locus_tag="ACIZE5_000115"
     CDS             125822..125986
                     /locus_tag="ACIZE5_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107306.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            126062..127204
                     /gene="dcm"
                     /locus_tag="ACIZE5_000116"
                     /pseudo
     CDS             126062..127204
                     /gene="dcm"
                     /locus_tag="ACIZE5_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            127194..127484
                     /locus_tag="ACIZE5_000117"
     CDS             127194..127484
                     /locus_tag="ACIZE5_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107307.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            127743..128927
                     /gene="mobT"
                     /locus_tag="ACIZE5_000118"
     CDS             127743..128927
                     /gene="mobT"
                     /locus_tag="ACIZE5_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HGC6107308.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            128924..129061
                     /locus_tag="ACIZE5_000119"
     CDS             128924..129061
                     /locus_tag="ACIZE5_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HGC6107309.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            129807..131717
                     /gene="ltrA"
                     /locus_tag="ACIZE5_000120"
     CDS             129807..131717
                     /gene="ltrA"
                     /locus_tag="ACIZE5_000120"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HGC6107310.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            131821..132045
                     /locus_tag="ACIZE5_000121"
     CDS             131821..132045
                     /locus_tag="ACIZE5_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107311.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            132058..132561
                     /locus_tag="ACIZE5_000122"
     CDS             132058..132561
                     /locus_tag="ACIZE5_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HGC6107312.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            132621..133010
                     /locus_tag="ACIZE5_000123"
     CDS             132621..133010
                     /locus_tag="ACIZE5_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGC6107313.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            132997..135444
                     /locus_tag="ACIZE5_000124"
     CDS             132997..135444
                     /locus_tag="ACIZE5_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC6107314.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            135449..137572
                     /locus_tag="ACIZE5_000125"
     CDS             135449..137572
                     /locus_tag="ACIZE5_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HGC6107315.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            137569..138573
                     /locus_tag="ACIZE5_000126"
     CDS             137569..138573
                     /locus_tag="ACIZE5_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HGC6107316.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            138592..139503
                     /locus_tag="ACIZE5_000127"
     CDS             138592..139503
                     /locus_tag="ACIZE5_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGC6107317.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            139690..139946
                     /locus_tag="ACIZE5_000128"
                     /pseudo
     CDS             139690..139946
                     /locus_tag="ACIZE5_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(140163..140378)
                     /locus_tag="ACIZE5_000129"
     CDS             complement(140163..140378)
                     /locus_tag="ACIZE5_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107318.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(140627..140845)
                     /locus_tag="ACIZE5_000130"
                     /pseudo
     CDS             complement(140627..140845)
                     /locus_tag="ACIZE5_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
     gene            complement(141140..142579)
                     /locus_tag="ACIZE5_000131"
     CDS             complement(141140..142579)
                     /locus_tag="ACIZE5_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6107319.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            complement(143167..143799)
                     /locus_tag="ACIZE5_000132"
     CDS             complement(143167..143799)
                     /locus_tag="ACIZE5_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HGC6107320.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSFGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            complement(144148..145599)
                     /locus_tag="ACIZE5_000133"
     CDS             complement(144148..145599)
                     /locus_tag="ACIZE5_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HGC6107321.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            complement(145711..147054)
                     /locus_tag="ACIZE5_000134"
     CDS             complement(145711..147054)
                     /locus_tag="ACIZE5_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGC6107322.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            complement(147188..>148599)
                     /locus_tag="ACIZE5_000135"
     CDS             complement(147188..>148599)
                     /locus_tag="ACIZE5_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HGC6107323.1"
                     /translation="PTVEGEKVEVGGTVDLTDNVTNLPALPEGTTVTDVTPGGTIDTN
                     TPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEIGGAVDLTDNV
                     TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNA
                     DKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTY
                     PDGSSDEVEVDVTVTDTRSDADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYT
                     WKEKVDVSTAGNKKGTVVVTYPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTG
                     KTEPNAEVTVTLPDGSQHHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNV
                     VVSSNKKDSGKNGSKGSKTDNQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGL
                     ILLGTLGLLGYKNRKKENE"
BASE COUNT        43347 a        30511 c        26948 g        47793 t
ORIGIN      
        1 gagtgtttcc cgattcattt ttggctgccg tagcaacttt tatatcatat cagagagaca
       61 agcgattgtc aactcttttt taaaagtttt tttcgatttc gtttttcgaa atctttcggc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcgt
      241 tagtaacatg tcaataactt ttttgttatg tttttgaata aatattttct tctgtctttt
      301 ggacaagtaa taatatacca actaaattta gcttggtcaa cgaatttttt gtattttttc
      361 aagttttttt caataaacga ttattcataa cttttctttc tttatcgttc gttttcgtct
      421 tctttaatgt ctagaatagt cggcattagc ttttgaactt tcgttattat ttattccttt
      481 ctacacagca aaagctgcct aaggaattcc ttagacagct tttattcgat tatctcattg
      541 ttgggaatag caaaacatcc cgaattgatt gtgcatcagt tagcaacatt actaatctgt
      601 cgatcccgat gcctagacca ccagttggcg gcataccgta ttctaaggct tccaagaagt
      661 cttcgtctac accgtgagct tcgtcatttc ctagttcacg ttctttttct tgcgcttcga
      721 atctttctct ttgatcaatt ggatcgttca gttctgtaaa ggcattagca aattcgcgcc
      781 ccactatgaa tagttcgaat cgatctgtga atcgaggatc ttctggattt ttcttcgcta
      841 aaggcgaaac ttcgactgga tgtccgtata caaacgtcgg ttgtgtcaat gtttcttcaa
      901 caaatgtttc aaagaattca ttgataacat gtccgacacc catagcttcg gttacttcta
      961 cattgtgttt ttcggctaaa gctaatgctt cttccaatgt catttcttgc cagaagtcta
     1021 caccagtttg ttctttgatt gcatctacca tatggatgcg tttaaagtca ctttctaagt
     1081 cgacagcttg tccatcatat gtgatttttg ctgttcctag tactttttca gctgcgttac
     1141 ggataatacc ttctgtcaga ttcattacat cattgaaatc agtatatgct gtgtatgctt
     1201 ctaacatcgt aaattctgga ttatgtgtag tatcaattcc ttcattacgg aaaacgcggc
     1261 cgatttcata aactttttcc attccgccaa caattagtcg ttttaaatga agttctagcg
     1321 caatacgcaa atataaatca atgtccagtg cattatgatg cgtgataaat gggcgtgcgg
     1381 cagctccacc tgcctcattg tgcaatactg gtgtttctac ttcaatatag ccattgccat
     1441 ctaaatagcg acggatttcg ctgataattt ggcttcgttt cataaatcgg tcaaagcttt
     1501 cgcgattact gattaaatcc aagtagcgtt gtctgtagcg ttgttcaata ttcgttaagc
     1561 catggtattt atctggcagt ggacgaagtg cttttgacaa aatcgtgatt tctgaagctt
     1621 tgatagaaac ttcgcctgtg tctgttttca tgatttgtcc agttacacca aagaaatctc
     1681 caaggtctgc atgtttgaat acttcatagg cctcatcacc tacttggtct tttcttacat
     1741 aaatttgaat ttggccttca cgatcttgta gatgcgcaaa tccagctttc ccttttcctc
     1801 ggcgagtcat catacgacca gctacactag cggtcaatcc catttctgct agttcttctt
     1861 ttgttcttgg atcaaatagt tcatgcaatt cttctgagtt gtgcgtgcgt tcaaatcgtt
     1921 ttccaaatgg atcgattcca tcttcacgca attgttccat tttttgacga cgtacaagca
     1981 tttgatcatt taaatcttct acttgatgtt gttgttcctg tgtcacaaaa gttcctccat
     2041 tctcatgtta atctctttcc tataatgcca atgaaacaca aaaaaagcaa gccgaacttg
     2101 gaatttcggc ttgaaaattc acgaaaaact tagaaatcac aacgtttgtt tcaatagtac
     2161 tttttccgct ttttctacaa attgatccag caggtcattg atttcttgct gtttttctgt
     2221 ctgattgatt gctactttca ctttcgctgc tcgaggaatc ccttttaaat aataagccgc
     2281 atgtgttctg aattctctac aagctacttt ttctcctttg agatctgcta agcgttgtaa
     2341 atgaagttta gctgtagcaa ttttttcggc tggtgttggt tcaggaatca gttcccctgt
     2401 ttcgagataa tgctgtgtgc ggtgaatcat ccatggattg cccagcgctg cacgaccaat
     2461 catcacaccg tctgcaccga catagtcaag catccatttt gcatcttctg gcgttttgac
     2521 atccccgttc cccataaatg gaatcgtcaa atgttttttc acttctttca atacttccca
     2581 gtccgctttt ccttcataca tctgaacccg tgtacgtcca tgcatagcga tggcacttgc
     2641 tccagctgat tgtgctgcta atgcattttc tacagcaaag acgtgctctt catcccaacc
     2701 aatacgcatc ttgattgtta ctgggatatt tactgctgaa gaaacagctt ggaccatttc
     2761 gtatactttc tcaggatcta aaagccattt tgctcctgct tctgctttga ttactttatt
     2821 tactggacag cccatattga tatctattat atcggcagct gtgttttctt cgacaaattg
     2881 agcagcttca actagactat ctttatttcc gccaaatatc tgtaaactta atggatgttc
     2941 tgtttcttca atgtggagca tctctaaagt ttttttgttt ctgaaatgaa taccttggtc
     3001 actgatcatt tcacatacga ctaagcccgc accaaattct ttgacagtga ctcgaaatgc
     3061 tgaatttgtt attccagcca tcggtgcaac aacgacacga ttagggattt ccacattgcc
     3121 aattttccat gtgtgttcca cttaaatccc tcctaaggct tctttcttca atccatctaa
     3181 ttcttcttcg ctatacttgt atttgttatt acagaaagaa caaaccgctt ctgcaccgtg
     3241 atcttcgtct atcattgctt ggatttcttc tgcacctaac gcgataattg cttctgcaaa
     3301 tttttctttt gaacagtcac atttgaattg aacaggcatt ttttccaaaa tgttcaattc
     3361 ttctgtacca agcaatcctt tcaatatttc ttctggtgtc tgtccttcat ctaagagggt
     3421 agagattctt ggtgtcgttt ttaattgttc ttcgatcttg ctgattgttt cttcatcggc
     3481 acctggcatg atttggatca tgaatcctcc cgccgtcttg atgctgtcgt cagtattgac
     3541 caatacactc agtccaacag ctgaagggat ttgttctgag atagcaagat agtaagtaaa
     3601 atcttcagcg atttctccag aaacaatcgg cgtttgccca gaaaaaggtt cttttaatcc
     3661 taagtctttt gtgacagtaa acattccttg tgttccaact gctccccgca catcgatttt
     3721 accttcacta tttagaggaa gactgagatg cggatttttg atgtaacctt tcacatctcc
     3781 ctttccattt gcatctacta caattcctgt tgctggacca tcgccttgga ttcgaacagt
     3841 tagtttgtct tctcctttga gcgtcgcacc aagtagcaga ctaccgacca atgtccgtcc
     3901 caaagcagct gaggaggtgt gccaagtatc atgacgtctt tgtgcctccg ctacggtatt
     3961 tgttgcttga acggcgtatg ctcggacgaa tccgtcgtga gcaagtgcct taaccaaata
     4021 atctttcatt tgttatgtac tcctttttcc gtttttaaac tcatagtgaa tcatactagc
     4081 aactactgct tttttcaact ttggaatgct tcttttaaaa ataattcaga atcatctaga
     4141 aaacaggaca tcaccctatt tacaacttaa ataaagaaat ctcccgaaaa ccggtttttg
     4201 ttccggtttt cgggagtcat atcagatcaa ttgacctata tttttttatt tgtattgatc
     4261 gtctgaatga ttatcttctg attgttgaga atctgaatca tgttctgctt tattttcctc
     4321 attcagttca tgttttgctt cttcaaaatc acgtttttct tccgcttgtt tttcagcgtc
     4381 tttttcttcc aaagcacgtt ttgcttcttc aaaagttttc gcttcttttt cgcttggata
     4441 atcatttgac tcagtacctt caggcatcac accgtgttca aacaatgact tgattgcttt
     4501 ggcatccaat gtttcgaatt ccaaaagttt ttcagcaatc agtttatgct gtgcacgatg
     4561 agcttcgatg atttctcgag ctttatcatg agcttccatc aagatttttc gtacttcttg
     4621 atcaatctcg aaagcgactt gttccgagta agcttttgtt tgaccatagt cgcggccaac
     4681 aaacacttga tggtttcctt catattgaac aggacctaaa cgatcactca ttccatattc
     4741 tgttaccatg cttcgtgcta gagctgtcgc ttgctcaaag tcattggaag caccagttga
     4801 ttggacattg aagatgattt cttcagctgt acgtccacca agtaagccta cgatttgttc
     4861 aaacatatct tctttcgtca tcaagaactg atcttctttt ggtaaagcga tcatatatcc
     4921 gccggcgcgt ccgcgaggga tgatcgttac tttgtggacg acccgagcgc gactcaatac
     4981 taatccgaca atcgtatgac cagcttcgtg ataagcaacc atttcgcgtt cttttttgct
     5041 gattacgcga tcttttttag ctggacctgc aatcacgcga tcttccgctt catcgatatc
     5101 agaagcatcg attttctttt tatttcttct agcagctact aacgctgctt cattcaagac
     5161 attttctaaa tctgctccgg caaaacctgg tgtctgttga gccacaactt tcaagtcaac
     5221 gtcatctgcc atcggtttat tccgtgcatg gactcgcaag attgcttcac gaccttttac
     5281 atctggacgt ccaactaaaa tctggcggtc aaaacggcct ggacgtagta acgctgggtc
     5341 tagtacatca gaacggttgg ttgcagcaat gacgattact ccttcatttc cgtcgaagcc
     5401 atccatttct acaagcaatt ggttcaatgt ttgttcgcgt tcatcatgtc cgccgcccat
     5461 accggcacca cgttgacgac ctaccgcatc aatttcatca atgaaaatga tagctggtgc
     5521 gtttttcttc gctgtttcaa acaaatcacg aacacgactt gctccaacac cgacaaacat
     5581 ttctacgaaa tcagaacccg agatcgagta aaacggtact ccagcttctc cggcaacagc
     5641 ttttgctaat aaggttttac ctgttcctgg aggtccttct aaaagtacac ctgccgggat
     5701 acgggcacct aattcaacaa atcggcgagg atctttcaga aattcaacaa cttcaactag
     5761 ttcttgtttt tcttcttccg cacccgctac atcagaaaaa cgtacgcgat tagctttttt
     5821 gtctgcttct ttggcttttg atttaccaaa gttcatgaca cggccgccac cgccaccgcc
     5881 gccgccttgt tgtcccatca tcatgtaaaa gaaaaagatg atgattacga ttggcaagaa
     5941 gctaagcaat agggaaaccc atataccgct gcttgattct tcttttactg ttgtagcaac
     6001 tttgttttct tttgccagtt ctgttacttg gctcaatgtt gtatcatttg gcaaaatgat
     6061 tgttgtgaaa tgggtagtag tcgtatctgt tgaacctaag atagctaacc caccgctgtt
     6121 agcgacggtc tgctgttctt tgtattcacc agtgatctta tatacaccat ttgcaggctg
     6181 cacttcaaat tctttgatct tgcctgcttg tagttgttct gtgaattttg agtactcgat
     6241 atctgacgat cgctggccgt tattaccaaa aatgaaataa acgaccatta ccatcgctaa
     6301 gattacgagg acataataca aggcattttt catcatgccg ttgttctttt tgttcatagt
     6361 tgccctccct aagcgtcaat ttaatttaac agttttttat caatcctgac cattctattg
     6421 taccataatt taattgagat acagcattaa tttgattgat aaacactagg tttcaataca
     6481 ccgatgtacg gaaggttacg atatgcttct gcataatcca agccataacc gaccacaaat
     6541 tcatttggta cgttgaagcc aacataatct gcttcgatat ttactactct tccttcaggt
     6601 ttgtcaagta gtgtaacaat tttgactgat tttgctttgc ggtatttgaa aagatccact
     6661 aaataagcaa gtgttcttcc gctgtcaatg atatcttcaa cgatcaacag atcgcgacct
     6721 tctacattcg tatctaagtc tttgacgatt tttacttccc ctgacgagac tgttgcattc
     6781 ccgtagcttg aaacatccat gaaatccaat tccaaatacg tatcgataga acgaacgata
     6841 tctgccatga atggtaccgc tccttttaag acacctacta ctaggggatt ggtgttttgg
     6901 taaatttctg ttaactcttt gcctagttct ttgcaacgaa cttgtatctc ttcttgtgag
     6961 atcaaaattc tctcaatatc cttttccaac atcaggttct ccttccaatt gcttcttttt
     7021 gatatttgta aagaagtatg tagtgtattt tatcagtttc ttcacgaata ctcaaatatg
     7081 aaaaggcaaa aggtatcaag ctatatatat ttcttttggc atctgtaatg atccaagcat
     7141 gctgcctttg tgaattaggt actttctgat cgataaaata tctagatact ttttttgtga
     7201 gattctctgt taatttaatg cggtctcctg cttttctttt ttcgacatac agttgcacat
     7261 cagcaggaat ccaaatgtca tgagaaaata gagaccatga atctgttgct ttgatgtccc
     7321 ctgcattttc aggtttgacc agaccaatcc attctgtttc attcaaatat attccttgtt
     7381 ctggaatcag caacaagcgc tggtcttctg tctggctagt tgcttgtttt tcttttttag
     7441 agagtacaac aaaatgatac tctcttttca gtatccaatt attgccaata ctgagttgcc
     7501 attggctttt tttctgttgc cactggtcta aaatcgactc catttgttgt tctttcaaaa
     7561 taattcctgt ttttgagaat gctttgtcga aaaaggagta aaaaaaatag tatcgttcag
     7621 catctgtcat ttcttcaatc atttctgcag aaaatcgaaa ttgttcctcc cactgttcga
     7681 cttccttttc gatcaactgt cccatatatt tttgaatgac ttggtctgcc cattggatct
     7741 gttgcgaaaa ttgctggaaa tgtctcaacg cctgtgtatt ttcttgtttc aattgaggaa
     7801 ctaccaaatg acgaagccga tttctctgga tatctaacaa ttggtttgtc tgatcctcaa
     7861 agtaaacaag ctgcgattcc gctgcataag tatataggtc ttctttgcta aaactcagca
     7921 acggacgaat cagtctgccc gtagcaaatg gttgtacttc tttgattcca gaaaaagtat
     7981 ttaactgtcc cccacgaacg attttcatta acaccgtctc gatttgatca tctccgtgat
     8041 gagcagtcat caacgtgtca tattgtcctt cttccatcac gcgagtgaat tcttgataac
     8101 gaaagttacg agcttctgtt tctatggcgg atttggctgg atcttcccaa atacttacat
     8161 ataaagggag attcttctct tcacaatatg agcgaagata ggcagcttct tctgctgatt
     8221 cttctcttaa ttggtgattg atgtggacga tacctaaaga aaaaccgatt tggcgttgca
     8281 cttgtaaaag taaatggagc aaaaccatcg aatcaacacc acctgatacc gctgctaaaa
     8341 ttctcgatcc ttgttgccag aatccttgtt cattcccgtg ccgaataaat gactgctgta
     8401 atagcggtgc ttttttcccg cctttttcaa cgttcatcct ttccacaccc tttcttccta
     8461 aaaaaaagag agcgggaaaa cgtctaaaac gacaattaac ctgccctctg ttgatactat
     8521 gacccaaata gtcgcactat cattatttgc ggctttttag ctgcgacgtc cgccacggcc
     8581 accgcgcttt ccttctgtgt ttcgcttcaa tgaagataag cggtcatcgc tatctttcaa
     8641 aaatgaactc atcaatgaat cgaagtcttc tttttgagct gaaggttgac tgcgagaaaa
     8701 agattttttc tgtgctggac gatttcggtt gtcacgggga tctttttgtt gatatttttt
     8761 aggacggctt tcttctccag attcagcagg ttgttcctgc gctttccgga tagatagtcc
     8821 gatttttcca tcatcattta ctgaaataac tttaactgtt acttcatctc ctacacttaa
     8881 aacatcatgg atgtctttta catagccatt tgacacttcg ctaatatgaa ctagacccgt
     8941 ttttccagca cctagatcaa taaacgcacc aaaatttgtg attcctgata cttttccttg
     9001 cagttttgct cctacctcga ttgacataaa aaaaatgttc ctcctaatta tttccctttt
     9061 ttatattcct gcttattttg cagttgtaga actagttgat tgatctgttt catttgtcga
     9121 gctgtctgta tttgattcta atataggata aactttttca ccgtcttttg agtaaaagaa
     9181 tttgcttctg gcaagtttag ctacatactc atcatctttc agcaatgaaa catcttggtg
     9241 cagctgatca acgtctgcgt tgacttcttt catttcagta tttgcttcga ctctcaattc
     9301 gttcaattga tgcatccttt gcatgtcatg gaaaatctgc acacctatta tcgcgaaaat
     9361 gaccaaagca ccaacaaaaa ttgcagccag tctgcgtctt cgaaaaatca gttgacgttg
     9421 ttgttgctga aattcagcat actttttctt tgcatattcc gtatctagcg cagcgatttt
     9481 attgcttttt ttcgtcactt ggattcgctc caatcttttt gattgtcttt ttcattatac
     9541 caatatcgtg aaagcttgtc taatctattt ctctagtgtt tctgtgcgat tttcagaaat
     9601 aatttcgtac attttttgtg catcttcttt tttggttgat tcatgtaatt ccgtaatttt
     9661 cacttccaac gttttgttgc caaactggac tttcaaaata tcgcctactt tgacatcact
     9721 ggaagatttc gccaatttac cgttgatttg aattcttcct ttatcagcta cttcttttgc
     9781 tactgatcgt cttttgatga ttcgggaaat ttttaaaaat ttatctaatc gcatatctta
     9841 ttcctcactt tttaattttt ttatttaatc gcaggatttt cttaccaaaa ggcaacatta
     9901 gccattctcg tactgtaaac agacgaagac gaatcactgc ataaatgaac acagaagccc
     9961 cgatcccaac tcctatcacg ctgacaaaaa aagcagtgga acgatgagtt acaggaccaa
    10021 atactatatt caatacacca taatacagca gcagtactac tgtcatacaa agaaggctga
    10081 acatcaactt ccgtccaaaa tgccgttctt tccaaaaagc atttagctct tttgtttcaa
    10141 ttcgaacaaa ataccaaagc gtcacaccta atcctaaaag ggtagacagg cttgcacctg
    10201 ctgttcctaa taaaccggtc agaaaagaag tagtcaatcc ttttaccaat agtccccatc
    10261 ctgcgccttt taaagaaggg cgaaacgagt tcttgctttg agcaatactt tgataagctt
    10321 ggatgactgc agtgaaagca atggaaaaaa caaataatac aagcgctgca tttcccgcat
    10381 aatctttaaa caacgcataa ttgatataag ggagcagcaa ggctaatccc aaagacgcag
    10441 ctaatgctaa agcggtcgtc aatctaagat agattttggc tgtctgtaaa aactgacgat
    10501 agatccggtt ggtcaaatga cgagtcaacg caggcaggaa tgtcgcactt aatgcagtgg
    10561 caatcactaa acctaattgt actaaaggct gacctcgatc atagacccct tttgctatct
    10621 tcgcaccgta ttctgacagt ccgtaaactt ccaaagcatt ttttacaaag aaagagtcga
    10681 tcagctggaa aaagataagc aatccactat aaatcgaaac cagtccgcct tctaccagaa
    10741 aacgccggat caagggcttt gacggctgtt tgaacaatgg aaaccgtcgg aagcttaacg
    10801 ctcctccatg aatcttttgt tcatagtagt gaaggatccc atatgcgcat aaaccgccaa
    10861 aaacagctcc actcattgct gccgtccctg tttggtacac cgtccatcca agctttctaa
    10921 aagcaaacgc actacagaca atcacaaaaa cacgaacgaa ctgctcaact acttgagaaa
    10981 cagcagttgg ttccatcaag aatcttcctt ggaaattccc tcgataaaaa gatagaccag
    11041 gcatcagcaa aaaggtaaag gaaactactt ggatcagcgg tttcaattgt atgtctccca
    11101 tcatccaagc aatccagctg ctaaatgcaa agacaaacaa ccacaaaaag acacctgtcc
    11161 aaaatactaa gggataaaga ttttgcaaag cttgctttcg ctcgaaagga ttctttcttt
    11221 ctgcaacgta ctttgatatg aactgcggaa gaccggataa agctaaagtc attgctatcc
    11281 cataaattgg ataaacttgc tgataaacat aaaaaccttc gtcgccgact aagttttgga
    11341 ggggaattcg gtaaagggca cttaatactt ttgctatgaa agaagcaatc gtcaatacaa
    11401 atgctccttg catgacgcgc cgcatttctt tatgatccaa atcattgctc cttcctacgc
    11461 tgacagatat ttttgctcac gcaacgcttt gacaaacttt tggatttcct gaagccatac
    11521 tgcttcttcc atttggttgg ggatcgtcaa gcgtatcacc atctgttctt tttcaacgcc
    11581 tagactggct tttagttttg tcgctgtcag tgcttcgaat aactgttcca cactatagcg
    11641 ttttgttcca actttactta gagtaaagac tatatgcgcc tcctgtttcc ttatcgtttc
    11701 taggagcgct cgatcgccat ccattttgat ctgcccaatt gtcaagagat gtgctacttc
    11761 ttctggatat tctccaaaac ggtcgagcag atcatcttct agttcatcta gcatttcttg
    11821 cgaatcaagt tcacgaattc gtttatagat ctcgattttc tgccgttgat ctgccacgta
    11881 tgtttcaggt agatacgcat cgacaccgag gtcgatctca acagtggtct tctccacttg
    11941 actattcttt ccttgtttac gagaaacagc ttcgcttagc atttgagaat acatatcgaa
    12001 accgactgca tcaataaatc catgctgctg agcacctaag agattacctg caccgcgaat
    12061 ggaaagatcc cgcatcgcaa tcttgaatcc agatcccagt tctgtaaaat ctttgattgc
    12121 ctgaagacgt ttttcactga cttcgttaag gatcttctgc tgctcataca taaagtaagc
    12181 atatgcgaca cggctgcttc ttcctacccg ccctcgcaat tggtataacg tggataatcc
    12241 catataatca gcgttctcaa cgaacaacgt atttgcgttc gggatatcta ctcctgtttc
    12301 aatgatggtt gtagtgacaa gaacatcata ttgaccttca ataaattcaa aaagcgtatt
    12361 ttctaattgc gcctctgtca tttgcccatg agcataaccg atccgtgctt ccggaacgag
    12421 ttcttggatt tcttctactt tttgttcgat cgtttctacc cgattatata aatagaatac
    12481 ttgtccacct cgtcccattt ctcgatggat tgcttcgcga atagccccag gatttttttc
    12541 cataacatac gtttggatcg gataacgatt cgcaggcggt gtttcgatta ctgaaagatc
    12601 ccgcacgcct aacatcgaca tatgcaaagt tctcggaatc ggtgttgcag tcagagtcaa
    12661 aacatccact tgtgcacgta actgtttcaa tcgttcctta tgttttacac caaaacgttg
    12721 ttcttcgtca atgatcagta gacccaaatc gctaaattca atatcttttg acaaaattcg
    12781 gtgggttcct acaacaatat caacttgacc tgtacgcagt tgttcgatgg tttctttttg
    12841 ttgctttctt gttctgaaac gacttaatag cccgatattt acggggaaac cttcaaatct
    12901 ttccagcatc gtttcatagt gctgctgtgc caagatcgtt gttggaacta aaaaggctac
    12961 ttgtttgctt tcctttatcg ctttaaaggc cgctcgaagc gctacttctg ttttcccata
    13021 accaacatca cctacgagta gtcgatccat tggtttttct ttttccatat cccgtttgat
    13081 ctccgctgca cttctcaact ggtcatcagt ttcagagtag gggaaggcat tttcgaattc
    13141 tttttggtag gcgtcatcag gtccaaaagc atatcctttt tctgactctc ttgcggcata
    13201 taatttgatt agatcgtcag cgatatcctc gatttttgaa gagacttttc gcttggtttt
    13261 cgtccattca cttccgccta gcttattgat gcgaggcgct ttggcttcag aggcgacata
    13321 tttttggatc agattcagtt gagtaacagg aataaacagt ttgtcgtcgt tttgatacaa
    13381 aatagtcata tagtcttggt gaacgccatc tacttctagc gtttccatcc caatgtattt
    13441 cccgatacca tgattggcat ggacaacgta atctcctgct tttaactcat tatagctttt
    13501 caatcgctct gcgtttgtta ctgtttgacg tctcgtttgt tttttcgtcg ttttttggaa
    13561 aatttctttt tctgtgatag ctactatttt ttcttgagga agttcaaaac cagcctgcaa
    13621 agctccttca actaattgta cctgtcctct gatcaatgca tttttttctg tttctactac
    13681 taatatgtct tcatctcgaa gcatttgttc tgctttgcgt attctgtcct ttgtcggaat
    13741 aaagatcaca acagtctgtt tttgcttgcg ccaacggtcc atttctgttt tcagcaatgg
    13801 catttgtccg aagaactgtt gcatcgtccg atattgaaaa ttatggattg cttggaaacg
    13861 aagatttccc atcccttttt ggaagagtga gaaaaaggtt gtggtgaact tttccttctg
    13921 cacgattttt tgtatatctg ctgaaaatgt ctgctcagaa aacacccgca attcgctgat
    13981 tttttgagtc tgccattctg ccgcttccct ttcgatttcc cgatttgttt ccatgattcg
    14041 ctgataatca tcaacgacta gtaaactatt tgaagggaaa taatccaaga tcgtcacaga
    14101 ttcttggtaa agaagatctg agtagaattt tgcttcttct gtcgggacac ctgcttgcca
    14161 gcttgaagtc agctgaccga agtaatcttg caaaaactcg cggtctgctt cttctgtggt
    14221 cgcagcaagc cgtttttcta gcattttttg catttgctct attccatgtt ctagatcctc
    14281 tggtccgtag acttgttcac tcgttgggga aacccagatt tcttccgttt tttcgattga
    14341 gcgttgtgtt tctgcttcaa aataccgcat agaatctatc tctacatcaa atagttctac
    14401 acgaacagga taggttgtcg ttaacgggta aatatcgata atgcttcctc gaatactgaa
    14461 ttctcccggt tttgcgacca tctcttctcg tacatagccc atcaaagtca attggcgagg
    14521 aagattttcc acgtctatct catcaccaat atgccaattc aattgcgcct gtagccaagt
    14581 tttcttattc ggcagtcgtt tgtgcaaaga tgcgactggc aacaaataga tacctgcttt
    14641 tttttcttga agtgcgttaa gcgttgcaac tctctcgcct cgcgcttctg gagaagaaaa
    14701 ggccatttca gcagaaagca cttcatccac tggaaataaa tggatctgat cttgcggaat
    14761 cacatgttgc agatcttctg ctaactgatt cgcataatac aaatttggca tcagaataat
    14821 catgttttta tttgttttct taaacgctcg agcaaataga agtgttttcg ctgagcccgc
    14881 taatcctgtg attagttgtc taggcatttt ttcttctaaa ttgctgaccc attcttttac
    14941 ttgcggatct tttccgacta attgaataat atccattcct tttcctcctt cctcaattga
    15001 atcgattcat cgcatccacg aacgaatgcc cttctatgag atattcgact gctttaacag
    15061 attgacacat gctttcttct atcaaaggct gattttcttt gctgaaagga ctaagcacat
    15121 gctggactac tgtttttttc ccttctggcc tgccgattcc caccttgatt cgatcaaaga
    15181 cattcgtatt caaatgggaa ataatacttt tgataccgtt atgcccgccg gcacttccct
    15241 tttgacggag ccggattttt cccactgcca gatccaaatc atcgtagatt acgactaatt
    15301 cctctggata aatcccaaaa taagtcatta gtgggccgac tgcacgacca gattcattca
    15361 tgaatgtttg tggtttgact aaaaggatct tttctccatt atgaaaaaat tcggcaactt
    15421 ctgcttcgaa cggatttttt ttgaaagtag cttgatgctc gcgtgcaatt ttatccacga
    15481 ccataaagcc gatattgtgt tttgtatatt ggtatttggt acctgggttt cctaacccga
    15541 cgatcatttt catttttgtt ttccacctaa ttctaaaaag cagcacaaaa ggctggactg
    15601 ctaattagcg gtccagtcca tcgagctttt ttctttttta cacttgtcaa tgcatagtat
    15661 aacacaaaac aaggcgtttc ggctaaaaga gaatcgttaa taaatgataa agaaattaaa
    15721 aatttcttca aagtttaatg aaataattga tatataaaaa tagtgaaata acgcacatgt
    15781 aagcttttac atataataca accttgttat ctgttatatt ttatagccaa atagcgtgac
    15841 atggggcttg agaaatgtta gcataagcat gggaaaaaac aaatcaatgg aaggattgat
    15901 actaaatgac tgcagctgca gaaaaaaaag atcatcaaaa agttattctt gttggagacg
    15961 gcgccgtagg ttctagctat gcctttgctc tagttactca aaatatcgct caagaagtag
    16021 gtattgtgga tatcaatact gctaaaactg aaggagacgc aattgacttg tctcacgctt
    16081 tggcatttac ttcacctaaa aaaatctatt ctgctactta cgcagacgca catgatgctg
    16141 acttagttgt tattacagct ggcgcaccac aaaaaccagg tgaaactcgt ttagacttag
    16201 taaacaaaaa cctaaaaatc aaccgcgatg ttgtcacaca aatcgttgaa tcaggattta
    16261 acggtatctt tttagttgcc gctaacccag tagatatttt gacttactca acttggaaat
    16321 tctcaggttt ccctaaagaa cgcgtaatcg gttcaggtac ctctcttgac tcagctcgtt
    16381 tccgtcaagc acttgcggaa ttagttgacg ttgatgcacg taacgtccat gcttacatct
    16441 taggtgaaca cggagattca gaattcccag tttggtcaca tgcaaatgtt gccggcttgc
    16501 aaatctatga atgggtaaaa aacaacccag aaatcgatga agaagctatg gttaacctat
    16561 tctttggcgt acgtgacgct gcttacacaa ttatcgagaa aaaaggcgct actttctatg
    16621 gtatcgcagt agcattagca cgtatcactc gtgccatctt agatgatgaa aatgctgttc
    16681 ttcctttatc agtattcatg aatggcgaat atggattgaa cgacatctac attggtgcac
    16741 ctgctgttat caaccgtcaa ggtatccaaa aagtaatcga aattccttta agtgacagcg
    16801 agcaagaccg tatggctgct tctgctaagc aattaaaaga aattctagat gaagcttttg
    16861 ctaaactaga cgctgaataa tctttgaaca tgacggaaaa catctattcg gtgttttccg
    16921 tttttttatt ttatcaccct tatggtttct aaattttttc ataaagtaga gataaccttc
    16981 gtcttttcct ctaaattatg ctatcatgag accgttccac cctaaacttt tacttaagga
    17041 gttgtcgata tgacaagatc ttcgcatcga aaaaaatcga aacatgttgc tttgctttca
    17101 gttcttggtg ttctcttagt gctgatcagc ttttatacct atcgcagtac atactacaca
    17161 aagcattttt tgccgaatac agaaataaat ggaataaatg tcagcaatct aacagtcgaa
    17221 aaagcaaatg aaaaattaaa agaagcttat tctgataaaa aactggctat taaagaagat
    17281 ggaaaagtct ggcaggaagt accaaaatcc gagctcggct acaaagatga tttcacttcg
    17341 gagctttctc cgatcctaaa tgaacaaaac ggatggactt ggggaatgac ttatgtctca
    17401 gcggcagaaa aacaagaaat agatcctgtc agtcaaaacc accaaaaact agacactacc
    17461 gttcagacat tgacaactaa gctgactgat ttgaacaaag accggacacc tactactgat
    17521 gcaacgatcg aaaaagcagg tgactctttc gttatcaagc ctgaagtcaa tggaaatacg
    17581 atcgacgtcg atgctgcggt caaacaatta aaaagtgcgg taaactctgg taaagataca
    17641 attgaattga ctgaattcaa agaaaaacca aaagtaacat ctgaagacag ctcactgaaa
    17701 gaacaactcg catccatgaa tgctatcgca aatgtaaaag ctacttacag tataaacggt
    17761 gagactttcc agatcccatc aagtgatatt atgagttggc tgacctacaa tgatggaaaa
    17821 gtcgatttag atacagaaca agtacgtcaa tatgtaacag atttaggcac aaagtataac
    17881 acaagtacga atgacacaaa atttaaaagt acaaaaagag gagaagttac ggtcccagtt
    17941 ggcacttaca gttggacgat ccaaacagac agtgagacag aagcattgaa aaaagcgatt
    18001 ctggcaggcc aagattttac tcgttcaccc attgtgcaag gtggcacaac cgctgatcat
    18061 ccattgatcg aagatacgta tatcgaagtt gatctggaga accagcatat gtggtattac
    18121 aaagacggaa aagtggccct tgaaacagat atcgtttccg gaaagccaac tacacctaca
    18181 cctgctggag tcttctatgt ttggaataaa gaagaagatg caactttaaa aggaacaaat
    18241 gacgatggaa caccttacga gagtccggta aactactgga tgccgattga ctggacaggt
    18301 gttggtatcc acgattcaga ctggcaacct gaatacggtg gagacttatg gaaaacccgc
    18361 ggttcacacg gctgcatcaa caccccacca agtgtaatga aggaattatt cgggatggtc
    18421 gaaaaaggaa cgcctgtatt ggtcttctaa caaaaataat atataaaaag aaagcacccg
    18481 tacgattggt acaggtgctt tctttttatt atctaacaat gtgctactta catttcagca
    18541 gcagtaaaga cttctgaaac atcatcatcg tcttctagct tatctactag acgttccaat
    18601 tgctcttttt gttcctcatt taaatcaatc gtcgtttgtg gaatcatcgt caattctgct
    18661 tgcgccaaag tgaactcttt ttccaactca tctcgtacag cagcaaaatc ttctggtgca
    18721 gtataaatct cgaatacttc aggagaagtt tgcagatctt ctgcccccgc ctctaataca
    18781 tcctcaaaca tcgtctcttc atcaacagtc aacccatcgc gttcaatagc gatatatcct
    18841 ttgcggtcaa acaagtaact gactgaaccc gtttctccca gtgatccacc gtttcgagta
    18901 aaagctactc ggacatttgt cgctgtccga ttacggttat ctgtcaatgc atggactaag
    18961 attcctactc cacccggacc atatccttca tacgtgattt catcgtaatt cgtttcatct
    19021 acggcactcg tagccttttt aatcgcccgt tccacattgt cgttaggcat atttgcagct
    19081 tttgctttgt ccacaacaag ccgcaaagct ggattcatag atggatcagg accgcctgct
    19141 ttagctgcca tataaatttc acgagaaagt ttctgaaaga ctttccctcg ttttgcatct
    19201 tgggcatttt ttcttccttg gatattatgc catttactat gtcctgacat gatttttcct
    19261 cccttgttct tttgagaata cacttctatt ctagtactat ttcacaaaaa aacaaagcca
    19321 cagccaatct ataaacgctt cttgaatgcc gcaaaaagca cacataatat cacagcagtc
    19381 agagcaccga tcgaatccaa catgacatct tggaacatag gtgttcgtcc accggtcatc
    19441 atctgatgga attcgtccaa acctgcgtac cctgttgctg aaagccaagc aaggatcgct
    19501 gtcagccacc aaatttttag cttggggaaa acacctaaaa acaagctgcc tcccaaaata
    19561 aaataggtac cgaaatgtgc gcccttcctt aaaaagaact ctaaaaattt ggcgtagccc
    19621 agatggttga tactcaccat acttccacca taattaaaac gtatacccgc taatgtgtct
    19681 ttaaatggct gattaggcag ccagctttct aatcgcgaaa cttgtgattg ctgtccgtaa
    19741 gtttgagaag aactgtaaaa taagattata acgactatca gtgcgattac taaataaata
    19801 tttccgtttt tcatttgttt ttttgaagaa ttcataagtc acctctgtat tttatcttag
    19861 actttttttg aagaaacaac aatcattttc atagagactt cttccataaa aaagtgctat
    19921 acttaatttt gtattacaat atgaagggag ttttttcatg agttattcat taaattggaa
    19981 tctagattct attttttccg gaggcagtca ttctgatgct ttgaaccaac ggatgaagca
    20041 attggaagac caaatgaacg agtattatca ccgcgtaaca aaatggtcac ctagttctga
    20101 caatgcagag cagttaaacg ctattcttca attgcaagaa acgattacga atggttttac
    20161 ccaatgcagc agctatatta ctgcattgct ttctgccaat gtcaatgatt cagatgcaaa
    20221 ggtcttatca ggcaagcttt acgcaatgct gcctcgtctg caatcagccg aaactgtatt
    20281 gtcaaagaaa tttgcagaaa tatctgacaa tgattggaat cagatgcttt ctcaatcttc
    20341 gtttgaaaca attgcttttc gtttaaacga gattcgtcgt gatggctcac aattattatc
    20401 agaagctgaa gaaaacatta taaatacgct ttctttagat ggtctaaatg cttggagcag
    20461 tcattatgat acgattgtag ccagcatttc gattcccttc gaacaagatg gacaagtagt
    20521 cgaattatct gctggacaag ccttcaataa gatgatgggc gatccagatc caaaagtcag
    20581 agaaacactt ttcgcagcat gggaagaagc ctggaaagaa aaggcacccc tcttcacgga
    20641 tactttgaat catttagatg gttttagact ttctgactat gaacttcatg gtgtcacaga
    20701 ttttctacaa aaaccattag agtacaatcg gttgaagaaa gaaacattgt ctgtcatgtg
    20761 ggatacaatc cagaaaaaca aacaacccct tgttaattac ttgactagaa aagctaatct
    20821 tttcggtaaa gaaaaaatgg aatggcaaga tcaagatgca cctattattt taggcgattt
    20881 gaaagaaaaa acctttagtt ttgacgaagc agcagcattt attatcgaaa actttaacaa
    20941 attcagtcca aaaatggcta aatttgccca atctgctttt gaaaagagct ggatcgaagc
    21001 agaagatcgt cctgggaaac gtcctggtgg ttattgtact gagttaccag aaacaaaaga
    21061 atcaaggatc tttatgacct acagtaattc tgttaatgag gttgcgacac ttgctcatga
    21121 actaggacat gctttccata gcagcacgat gtgggattta ccttctttaa atcgcgaata
    21181 tgccatgaat gtcgcagaaa cagcaagtac attcgcagaa ctgatcgtag ccgatgctac
    21241 attaaaagtc gcaaaaacaa aagaagaaaa aatcaatttg ctagatacaa aactgcaaaa
    21301 tgctttagct atgttcatga atatccattc ccgattcatt tttgaaaatc gattctatga
    21361 agcacggcaa gaaggattag tctcagaaga taagatcaca gagatgatgg ttgaggcgca
    21421 aaaagaaggc tatcaaggag ctttagctac ttaccatcca tatttctggg ctgcaaaatt
    21481 gcatttcttt attgatgacg taccgtttta taacttccca tacacatttg gctacctctt
    21541 tagtttgggc atctatgctt acgccaacca aaagggagca aattttgaag aagaatatat
    21601 ccatttacta cgcgatactg cctcaatgac gacggaagat cttgcgaaga aacatttgaa
    21661 tgtcgatctt acccaaccag atttttggca agcaggtatc gacatggtga ctgaagatat
    21721 ccaaacgttc atggaattga cagaagaatt tatctgattt ctattttatc acaataaaaa
    21781 aagagttagt ccagaatggg ctaactcttt ttgattaatc attcttacat gctgacagca
    21841 aagtcagggg caaaccattg aactgaacca acttttacgc tttcgcctgg ttgaggagca
    21901 tggatatatt gtcctccgcc taaagcaatc gctacgtggt aagttccgcc ttgtgacccc
    21961 cagaataaca agtctccagc ttttgcttga gaaactgaaa tttttgttcc agctgattct
    22021 tgaggaactg tccaaccacc gatgtcacga ccagttactt gcatgtaaac atagcgtgtg
    22081 aaccctgagc agtcaaagcc acttggatct ttaccgcccc aaacatatgg agtaccaata
    22141 tatttgtaag cttctgctac gattgctgca ccattcacac ttccagaagg agctggagca
    22201 ggtgttacag gttttggttg ttcaggtgtt ggtgttggcg ttggagccgg agtactactt
    22261 cctgtgccgt ttcctgtatc aacactttga tctgttgatg gtgttgtagg cgcaggtgtt
    22321 gttgattctt ctgttgttga agattcaggc actgttgttg attcttctgt tgctgaagat
    22381 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcgctgttgt tgattcttct
    22441 gttgctgaag attcaggcgc tgttgattct tctgttgaag attcaggtgt tgttgattct
    22501 tctgttgctg aagattgtgt agctgatgat gattcttcag tcattgaaga ttgtgtagct
    22561 gatgattctt ctgttgctga gctttgtgca gtagatgaag cttgagtagc ttgtgcttca
    22621 gcctctgctt gttcgcgtgc ttctttttca gctttttctt gtgcagcttg ttgacgagct
    22681 tgttctgcta gacgttgttg ttcacgaata cgagcttgct ctgcttcagc ttctgctttt
    22741 tgacggttca agtcagcttt cttgtcttca gcagttgctt gttcagcagc taatgaagtt
    22801 ttcagtacgt tcaaatcagc ttgtttagat aaaagatcgc ctttttgaga ttccaaagca
    22861 gcttggtttt cagctaattc ttttagttta gcatcgtttt cagctttttt gtcttctaca
    22921 gcttttttat cttgtttttg ttgttccatc aagtcgttgt ttgcttttac catcgttgtc
    22981 attgcttgaa cgcgtccaat agcatctgct aatgaatcag cattcaatac agcatcgatg
    23041 tagtttgagc ttgtgttgct tacttgtgct tcgcgtgctt gtttttggat tgtatcttca
    23101 cgtttttcaa tacgttcttg taaatctgca atgtctttta ctaattgtgc agattcttga
    23161 cgcaatgtat cttgttttgc taataggtct tgtgcttgtg tgttgatttc agaaacttgg
    23221 ctttctaagg catcgatttg tgattgtgca tctgcttgtt gatttttcaa gtctgcaatc
    23281 ttttgatctt gctgttgtat ctgagaatca aaatcgtccg ccgcggcagc gatcggtgat
    23341 gctacggcag tcaaggtcat tgaacatacc attactgctg atattaaact ctttttcact
    23401 cttcattcct ccgactggct taatttaata aatatctaaa tatatttaag tctttcttaa
    23461 cgatataaaa attgtaccat agcagtgtgt caacgatata atagttatgt tacaaaaatg
    23521 tttcaaaaca acttttaaaa atgacaaaac tgttcgtttc agaaaatgat catgaaaaag
    23581 ccgcgttaag tctagcattt cttaagataa caacgattct ttttcgcttt cgacctaaaa
    23641 ataaaaaaag aaattattca tcactgaata atttcttaaa gggaaaaatg aataatacaa
    23701 atataatcat gttcaacagc agtgtaggtc ctaaaaacct tgtaataaaa tacgtgttat
    23761 ttactactgc taatttaaaa atcaactgga ccaccatcgt aaacaattca taacccgtga
    23821 caaagatgat catactgaaa aattcagtaa agatgttgac atggataacg tctttcatta
    23881 catacatcaa ccatacaatt aaagggagag ctactgcata gataccgata acgccaatat
    23941 agtaagcgtc atagatagcc ccgagaacaa tcgtggtaat cagtaaataa cgtttttcaa
    24001 acgccatact gcaacataat aatgccaata tcagaaagtg ggcatttgac atataggtgc
    24061 ctttcgacca ctcccctagc attcttgtta aatgaccatc tatcaacatc aaaaagaaca
    24121 aaacgattgg cagatagtac ttcattgttt ctttcttcaa catggactaa tcctccgcta
    24181 gccgttggac aatcgtcaca actgacacgt catacatttc tgcataaggt ttcacataaa
    24241 cttcccgatc cagcccataa ctatctggtt tcgttttaat aaccgtaccg atcggcaagt
    24301 tagctggaga attccctcca agaccggatg tctggacaac atccccttct ttgatatccg
    24361 tatcaccagt taattgggtc accactaagg catggagctt ttcatcatag tttttaagca
    24421 aaccaaacgc ttcgccatta gccgaagata cccgtactgg aaaatgattg gagctttcat
    24481 tagaggatga cagtaattcg attttagacg aagccgtatt gacctcgatc actcggccaa
    24541 tcaatccttt ttgcgacatg actgccatat ttgcttcgat accgtcttta gaacccttgt
    24601 ctacgatcag catgtcctgc caactgtcag gcgaacgagt aatgacattt gccgttactt
    24661 tttcgtaact agtcagcgtc tgattcaact caagttcttt tttcaacgct tcgatttctc
    24721 tctcgtaatt cttgttttgc tgtgaaacgt catcatagct atcgattttt tcttttagcc
    24781 gctcattttc ggcataagtt gaaaaaagat tatggacaga atctactcca tttcgtaccc
    24841 accgtactgg ggcagagatt gttttatcaa ccattgcaac actgtcatta acgatggatt
    24901 ggaagaaatt gggctttcct tcattcgctc gctgcgcagc ggtcacactt agtatcgtca
    24961 ccacgatgat aacaataacc aaggtaataa taatattttt attaggattg aacttcttca
    25021 caaagacacc tcgaattaat tagactcttg tgttcaattt tatcactaaa tgccgtgaaa
    25081 caaaaggtaa gttgctcctc ttaagctttt ttttagcaaa taatagattc tgtcattttt
    25141 agcctgaaag acaaattttt ttatttgttt atggatcaat ctttgctttg aataactgca
    25201 atcataccat ctgaaaaaga aaattctgcg gtatctgaaa gaaattcgtt acttgcataa
    25261 gatgtcggat attctacttc tttattttcc aatacatact tgctgccttt taatgtaaga
    25321 ttcgagacgg gagtcaagca gcaataagct aaatacttca tatctggtat ctgtcttact
    25381 atatgctctc caggcaaata ataagacaaa taattttgac aatctctgat aataagctga
    25441 tgggcaaagg gtttgaagcg aggttccata cctaaccaga gattggctaa aagatgatcc
    25501 aatcttccgc ccgtagctcc aatcaaagtg acttccgctt gcgggtaacg ttcaaatgtt
    25561 tttaagatac ctaactgtgt atctgtatcg tctttttctg caggggaacg ggtatactct
    25621 ttggcttttg caaatacttc cttctgctct tcgttcgaca atgaatcaaa atcacccact
    25681 gccagatcta ctgggtagcc tgcttgaagc aggtacagcg caccacggtc tatcccgaca
    25741 taggcatcgt atttggacag cagagactgc ggccagtttt gcggattacc tccagcagct
    25801 aataaaattt tcatttagtc taatgcctct tttaatcgtt cgatttgtcc gactggattt
    25861 tcggctccat agatatatga tcctgcaacg aagacatccg cccctgcatc tttacagatt
    25921 tttgctgttt ctggaacgat tccgccatct acttcgattg cataagtcca attgttctct
    25981 ctacgtagat cagcgagttc cgtaattttt tctactgttt cttcaataaa gctttgtccg
    26041 ccgaacccag gattgacagt catgactagt acttgatcag ccaaaggcaa aacatgtttg
    26101 atcatggaga ctggtgttcc tggattgata actactccag ctttaactcc taagcttttt
    26161 gtcatttgaa gtgcccgatg aatatgagga gttgcttcga cgtggacagt aatgatatct
    26221 gctccagctt ttgcaaatgc tggaatgtag ttttctggat caacgatcat cagatggacg
    26281 tctaacggta atttagtaac aggacggatt gcctgaacaa tatttggccc taatgtgata
    26341 tttgggacaa atcggccatc cattacatct acgtggatgt aatctgcgcc tcctttttcc
    26401 actaactcaa tgtctctttg taaattggca aaatctgcac tcaaaatgga tggtgctatc
    26461 ttcattcttg tttcctccta ttttcgttta ccttcttttt ttgcatacat tggttttctt
    26521 ttttcgattt cttgtaagaa ttgcaaataa ttgtcgtaac gtgtctgtgc gataccacct
    26581 gtttctactc tatgttttac ttcgcagcca ggttctttag catgcatgca ctctctaaat
    26641 ttgcaatgga cagaagcttc tacaaattca ggaaattgtc tcggcagttc tcctgcttca
    26701 attgtcaaaa agtcaatcga gctaaatcct ggtgtatctg ctactaaccc gccatagata
    26761 ggaatcagtt ccacatgacg tgttgtatgc cgtcctcttc caagtgcatc agaaatctct
    26821 cctgttgcta aattcagttc cggtgatatt tgattcagta gcgtcgattt tcctgctcca
    26881 gactgaccca taaagaccga tagccgttct gggaagtaac ggatcagttc tgtcgtatca
    26941 cccgtatgat tgggtacaat caccggatag cctattttag tataggtttg cttgatctct
    27001 tcgatttttt ctgggtcgtc tgacaagtcg gtctttgtca aaaaaataat cggttcgatc
    27061 gactcgtatt ccaaggtaac tagaaagcgg tcaagtagat tataagaaaa tgcaggctct
    27121 acgatacttg tgacaatgat tccaagatca acatttgtga ctggtgggcg aactaattga
    27181 ttttttctcg gcaagatttc cagaagatag ccgtctgttt gattttcact ctcaaagatc
    27241 acctgatctc cgacaagcgg cgtgattttc cgattccgga aatttcctct tcctcttgtt
    27301 tgataggtct ctccgtttgc gtatacatag taaaaaccgc tgattgcttt tctgatttgt
    27361 cctttgataa gtgccacctc cgtttttgtt tattttacca tacgaagagg aaagtaggtg
    27421 ttattccatg caaacttctc aaagtatatg gcttgaaaat tgatcaaaag agatagaaac
    27481 acaaaaaaga gaatgcaaca aatcaatgtc gcattccctt ctgatatatt ttattcagca
    27541 cttattttga actttctgag gtgctagctg atgaacttgt ggagctggaa gattcttctt
    27601 ttgaagagtt gcttgtgcta ctggagctac ttgagctgct agaactgtct gaagagtctt
    27661 tttcagaact agaagacgct ggatctggtc ctttagagta aattacgttc acaaccattc
    27721 ctttggtaat tgtcgttcct gcccctggta ctgtacgaat cactttatct ttatccaccg
    27781 tgtttgaata ttcggaagtc tcatgcccga tatattctgc accgacacta gctaaataac
    27841 tttgtgcttc gctttttgta tagccggaga tatcattcaa tttaggctct gttccttggc
    27901 ttacgacaaa attgatgtaa gtttcttctg ctacaacttc acccgaggct ggatcctgac
    27961 tgatgatcga acctgatggt acagtgtcgc tatagtcata agtagcacta atattattga
    28021 tattgaatcc ttgtgtaaca agccaattac gaacagtttc gtagttttct cctacatgac
    28081 tactcaaagt cactgtttct ggtcctttgc tgactgtgaa agtaatcgtg tctgttttag
    28141 gatcgacttc tgtatcttct gatggagatt gcgaaatgat cattccgctt tctacctctg
    28201 aactgaattc ctcttctttt tgaatcaagt cagcagaaaa ccctaattct ttcaaacttg
    28261 cttcggcatc ttcataactt ttaccactgt aatcatctaa tttgattttt ttcgtgccgc
    28321 tactaatata cagagtgact tcgcgttttt gcttgactgt cgttcccgct gccgggtctg
    28381 tcttcactac attaccttct tcgattttgt catctgcaat ttcttctgtt tttgttgcta
    28441 cttctaattt cgcttttgcg agtgtttctc tagcagaagc ttcagaaaga tcagaaacat
    28501 caggaacaac aacttctcct cgcccgccag aagcaaagaa tacagctgtt ccgattccta
    28561 aaacagcaag aatagctaat aggatcagcc accatttttt ctgtcctttc tttttaggat
    28621 caggcagaac ttcttcctcc tctggtaagg tttcgttttc tggcttgtct tttggcagag
    28681 gcatagattt gaatgaatca ggcattggtg catcttccgt aaggggtgtg ataacttttg
    28741 tttcattatc catcacatga ggctgccatt tttcttcgtt tgcacgagct ggtgataata
    28801 ctgtagaaag atcatcagac atttcctcgg ctgacttata acggtctgca ggttctttag
    28861 ccgttgcccg taaaatcacg ttttccagtg cttgtggcac atttggatca agtgctttta
    28921 tagatggaag atcatcttga aaatgtttta aagcaattgt tacagcagat tcaccatcaa
    28981 acggtacgct acccgtcaac atctcataaa ggatgatccc taaagcataa atatctgact
    29041 gcttcgttgc catacttcct ctggcctgct caggggacag ataatgaaca gatcctagca
    29101 tcgtattcgt ctgcgtgatc gatgtttcag ataaagcgat agcaatcccg aaatccgtga
    29161 tttttacaac accttcatta tcgatcagta cgttttgggg tttcaaatct cggtggatga
    29221 tttgatggtt atgagctaaa gaaatagcag aaaggatctg ctgcataata tttactgctg
    29281 tttcataagg aacaggataa tgtgtttgga tatatcgttt caagtccatt cctttgacgt
    29341 attccatcac cagatactgc atgttgtctt cttcaccaac atcgtaaaca ctaacaatgt
    29401 ttggatgaac gagttctgtt gctgctaaag cttctctctg aaatcgtcga atcgcagtct
    29461 ggtcattttg aaagtcaaat cgtaagactt taactgctac atcacgatcc aagattaaat
    29521 cgtgcgccaa aaatacattt gccataccac cgctaccgat atttccagtg atttgataac
    29581 ggccatttaa ttttttgccc aactcgatca tacactgtcc tccttatatt cgataagaag
    29641 aacggtgata ttatccgctc cgcctgcttc attggcacga tcaatcagct cagttacttt
    29701 atgagacaat gggccttctt gattgatgat cgttcctatt tcttcttcag acagcatgtt
    29761 cgtcaagcca tctgaacata acagcagtcg atcttttagt tgccaaagat gagtagaaac
    29821 atctacttcg actgttccag gcatgccgac agaacgtgtt aaaatatttt tccttggatg
    29881 gttcactgcc atttcttcgc tgatttctcc tgatttgact agttcattga ctaaagaatg
    29941 atcctccgtc aattgcatga ttttatcttc acgaatcaaa taagctctgc tatccccaac
    30001 attggcaatc gtgaaccagt catctgacag agcggccgct acgattgttg ttcccatacc
    30061 gttatattcc ggctgttctt gtccacgctg ataaatcagc atattttctt cttgaatcga
    30121 ttgaatgaac cattgggcga ttttttcatc gtcaacagct tcttgttttt cccaagcttc
    30181 gcctagattc gttaccgcca tctgactggc aatgtctccg gcacgatgac cacccatccc
    30241 gtctgctaat acagcaagct tgagacctga acggctggta aatacactgg catagtcttg
    30301 atttgtgtta cgtcgtcttc ctacatctga ttgatattca atctgcattt tttcacctca
    30361 ttactttttg cgcaaacaac aaatgaaaaa tccatctgtg taaaactgat gcggatacaa
    30421 agtcaacatt ttctcttcga ttgatgattg tagcatagga ttggtcaaaa catcaatcct
    30481 ctcaaaatca gggtgtcttt ccaagaaagc agaaacaacg tcttggtttt cttcttttaa
    30541 gatcgtacaa gtgctataag tcagaatacc ggaagacttt aaagttggtg cgcagctttc
    30601 taaaatttcc aattggattt ttggtaaatt cgctaattca tccggctgtt ttttataacg
    30661 aatatctggt tttcgccgaa gcagcccaag acctgaacaa ggcgcgtcta ctaaaatccg
    30721 atcaaactgc tctgcttcga actgtttact gacttctcta gcatccatct tttgagcgta
    30781 gacagcagaa gagacaccta gacgtgctgc attatcttca atgagtttga ctttgtgttc
    30841 gtgtacatct aaagcgacca cttctccacc gcatgacgga tctaaaaaag aagcaatatg
    30901 cgtcgtctta cctccgggtg ctgcacaggc atctaagaca tgatgttcag gctcgatttg
    30961 catagacggc gctacaagca tcgaactttc atcttggatc gtcatgacgc catcgtggaa
    31021 caatgagcta gaagctaaat gccctttttt cgctactata ccgtatggac tgacttggct
    31081 tttttcagct gtgatctctt cttcttgcaa aacagtgatg gcctgatctc tggaaagtcg
    31141 gcgtgtatct actcgggcac tagcatggct aggctgatat agcgataaac cgagcttttc
    31201 agtttcttcg tatccgattt gatccaccag tcgtttcgtc atccatagag gcaggctgat
    31261 tttgacagaa agtctttcga taggatcagc aatgccttgc agatctggtg ctccttgacg
    31321 ctgataattc ctcaagacac catttacaaa tttccctgtc ccaggatttc cttttacttt
    31381 tgcgatttcg accgcctcgt ttaaaatagc atgtgcaggg actttatcta aaaattctaa
    31441 ttggtataca gaaagataaa gaagcatctt gacccagtca tccacttttt ttgctttagc
    31501 gatcaatggt gcaacgtaaa attccaatag tcgctgatgg ctaatcgtac catagatcaa
    31561 ttctgtaaat aaacccacat ctttttgatt tagctcgctt tgtttgatca tctcattcaa
    31621 caaaagattc gagtaggcgc cacccttgtt cactcgctct aatgtcagta atgccatata
    31681 tcgtactgat tttttcattt ttttagggat ttttttcatt atttcacctg ctgaccaatc
    31741 tgaacttgct gaccgcttcc gttaaggaaa tcatgtacgg cctgttttcc tttaccagct
    31801 ggctgtaatt cattgatggc taagacggtc tgtttaccgc aagcaatcca tagatttttt
    31861 ttgtctttcc ggatgatcgt accaggtgct ttgtctgtag tttctgccaa tacttcaacc
    31921 gataataatt tccagcgtat gccctcatag gtcgtgaatg caattggcca aggacgcatt
    31981 ccgcgtactt ggttgtcaat ttcttctgca gttttatgcc aatcgattgc ttcttgttcc
    32041 cgtgtgatgt ttggcgaaaa agttgcttct gactcgtctt gaggtactgg tttttgtcca
    32101 tccaaaatat tgggcaatgt ttctagcaat agctttcttc ctaaaaggct aagcttttca
    32161 aacatcgtcc ctacatcatc ttgtttagtg attggtatgc tttcttgcgc atagattccg
    32221 cctgcatcca tttttttgat catttccatg atcgttacac cagtttcttt ctccccattc
    32281 atgatggcat aatgaacagg cgcacctccc cgatatttag gaagtaaaga agcatggaca
    32341 ttgattgccc ctaattttgg tacttgcaat aacttttcag gcaagaattg gccaaatgcc
    32401 gcagtgacga tcacatcagg caccaattca atgatttctt ccatttctgg cgaaccggag
    32461 attttctctg gctgcagcac acggataccg tgcttcagag ccgctttttt taccggtgtc
    32521 ggcgtaatta ctcgtttccg cccaactgga cggtcgggct gtgttaccac tgcctggatc
    32581 tcgtaacctg attctatcag cccttcaaga atcggcacag aaaaagcagg tgtgcccata
    32641 aatactagct tagtcatcaa gatgttcctc catatattct tcaagttctt cttccgggat
    32701 ctgctgtatc attttctcaa tgaacaagat accgtctaag tgatcgattt catgctggaa
    32761 ggcacgggct aaatagccaa aagccgtcac ttctatctct tctccgtctc gatcataata
    32821 acgcacggtc acttcatctg ctcgcttgac cgttccatag acatgcggaa tactgagaca
    32881 accttctacg tcaaggcttt caccttttgc ttcgatgatt tctgggttaa tcagttcaaa
    32941 tttctcgcct tcatctactt cgatcacagc aattctcttg ttttgtccta cttgaggagc
    33001 agcgatccct attccgtcat tcgcaatcat tgtctcatat aaattgtcta ataaagcgat
    33061 tgtctcgtcc gtgattacat cgattggctg agcagttctt tttaatttat cattagggtg
    33121 gatcaatata ggatagcgca taatttggcc ctttcttaaa taaagtttaa tggttcgttg
    33181 tcaattgcca caaaaagacc ttgtcgctgt tctttctggc ttccattcaa aatttcatcc
    33241 aaaacatgag gaagattcgg ttcatgttta tatttgatga ttagttgata ataatatcgg
    33301 tttttcactc tcaaaatcat gctgggcgtt ggccctaata gcaagctttg agggcttaac
    33361 acttctttta gctgattggc aatctgaaag attttctttg ccgctacttg ttcttcagga
    33421 tggctggcgg ttattttcac agtaaagtaa taaggaggat agcctccacg atgccgtaca
    33481 tgcatttcct gctgataaaa ctgctcataa ttttgttttt tagccaattc tatggcgtaa
    33541 tgttgaggat tgaatgtttg gatcacgact tcgcctgctt tttccgctcg ccctgctcgt
    33601 cctgaaactt gggtaagcaa ttggaatgta tgctcactag aacgaaaatc cggtaaattc
    33661 agggaggtat cagcattcaa caccccaact aatgtcactt ctggaaagtc caaaccttta
    33721 gcaatcattt gtgtccctaa taatatatct gcttcttttg caccgaattt ttgtaaaatc
    33781 tgttcgtgtg ccccttttct tcgagtggta tctacatcca tacgcaaaat cctagcttgc
    33841 ggataaagtt ctcggagttc ctcttctact ttttgagtac ctgttccata gtagcggatt
    33901 ttattgccgc cacaattagg acagcgattg ggaataggtt cttcatgtcc gcaataatgg
    33961 cagcgcattg aacgtgtatc catatgcagt gtaagagaga tatcgcaatt aggacatgga
    34021 agaacaaatc cacagtccct acacatcaca aaagacgaat atcctcgacg attgagcagt
    34081 aggacagttt gttctttttt gtctaatcga ttttgtattt tttcctgcaa attagcagaa
    34141 aaagtagagg tccgatgatt ctgaaactct tcacgcatat ctacgatctc aatagctgga
    34201 agctgtgcag ctgctttggc tcggtggttt aactgcaata actgataaac gcctttttga
    34261 gctcgtgctc ttgattctaa agagggcgtc gcgcttccta gaactattgg gcaatgatga
    34321 tatttactgc gccaaattgc tagatctctc gcatgataac gcggtgtctc atcttgtttg
    34381 taacttgatt catgttcttc atcgataatg atcagcccga tatttttcag cggggcaaaa
    34441 atagcagatc gtgcgcctac tactacttgc gcttcttccc gctcaatctt gcgccattca
    34501 tcatattttt caccttggga aagtccgcta tgtaagaccg caactgattc tccgaagcgt
    34561 cctttgaatc gctcgaccat ttgcggagtc aatgcgattt caggcactaa cataatagcc
    34621 gttttatttt ctgacaaaac atcagcgatt gcctgaagat atacttctgt tttcccgctg
    34681 ccagtgattc cctccagcaa aaagacctga tctttttgct gctgacctgc tgtgatgatt
    34741 tgttcgacag catttttttg ttctgcattc agttccaatg ccgtcgtttg gtcaaatact
    34801 cggtctttat aagggtcgcg ataacgttct gattctataa actccagcca gcccttttct
    34861 tttccttgat tcaagacagc agtactgatt cctttatttt tgaaataagc aattggttct
    34921 tcttggctca gttcagataa acacaaaaga agttcttttt gtttcttggc attttgccgt
    34981 aattttgccc attcttcttc gatttgcttt tcagttaaca aagaacggac caaacgaatc
    35041 gtttttactt tatttcgtgt atggacttca tatttgatat ctactaattg ctcttggcgc
    35101 cagcgaatca attgagaaag gctgccttct tcttctgctt ccttccagga aatcacttct
    35161 cgctgatcaa acaatacctg aacttctggt gtgtctgcca aaggatagat caatttatca
    35221 tattctgctt tcatcacact cggaagcatc gtttgtagac aagtgatttt gaatgcgtaa
    35281 gtaatttttt tcatataatc agctaatgaa agtaattctt cattgaccac cggagcaagg
    35341 tctagcaaac gaataactgc cttcaaagat ggattagctg attcttctga tttttggata
    35401 gccataacaa atccttggac atgacgattg ccattaccaa aagggacttc tactcgcatc
    35461 ccgacttgca aagctgtttc catttcagag ggaaccaaat aagtgaatgg ctgatcggtc
    35521 tgcatagtag gtacgtccac aatgacttca gctgttaatg tcatggttcg tttcctcctt
    35581 tttttgtctt ttcttatcaa gcgacaaaaa gttccttgcc tattttacta gagatcgatg
    35641 gatttgtctt atcttctgcc aaatcctaac aaaaaattaa cagcagataa gaaaaaaaag
    35701 aactgtgtca aaaagttcag acacagcctt ttctaccaga caataagtgg cgaatgtttg
    35761 aaaaggaaac agctgggttt gcttttcttt ttagatgttc gctctatttt tctttattac
    35821 attttttgct cttcacggat acgtgattcc aattcgtgtt gttcacgctc tttttgtgct
    35881 tgacgttcct cttcttccat cttcaaacgt tcacgtttta attcaggatg tggatcattg
    35941 actacatttc ctgcatcgat ttcttctaaa gcttgaccga cgctttttac tgaatcaaaa
    36001 gaatctagag taggctgtgc acttgcatcc aattcatgcg cgcgtttact tgctaaaatc
    36061 actagagaat attttgaatt tacacgatct aatagtgagt caattgaagg ttttaacatc
    36121 ataagactac atctccttta acattttaat atatttaccg attacgcgat ctactcgaaa
    36181 atgttcactg gcaataatgt ttttgattcg ttcaactgct agcggcactt catcatttac
    36241 aacagcatag tcgtaaagag ccatcatttc gatttcttct tttgcaactt tcattcgttt
    36301 ttcgattact tcatctgcat ctgttcctcg gcctacgatc cgtgatttta attccgctaa
    36361 atctggcgga gtcaaaaaga tgaatacacc atcgggcact ttttctttga cttgttttgc
    36421 tccttggact tcaatctcca agaaaacatc ttttccttca tccaatgtct tgttgacata
    36481 tgacaaagga gttccataat aattcccgac atattctgcg tattccagca tctctccagc
    36541 ttcgatcatt gattcaaact cttctttgct tcggaagaaa taatcaacgc cttcgacctc
    36601 cccttcacgc attttacggg tagtcattga gatcgaatac tgaaaatcat tatcctcact
    36661 ctcaaaaatt gcttttcgta ctgtgccttt tcctacaccg gatggaccag acaacacgat
    36721 taataatcca cgctctgaca tgacgacgtc ctttcaacta gtctttttgt acttatcgtt
    36781 tattttgcac tttttttctg caactttcaa ggttatcttt aattatagct agaaattggt
    36841 aaaaaagcta ccctgtacca agaggtcgta aaaaagctgt cctgcatcaa gtaataagaa
    36901 cagccaaaca taaacagctt ctcatgtttt tcgtttggtt ggggttatta tcgcagatgc
    36961 aagcttttga acgccgtgta taagaggtcg tgaagaagcc gattagtttc gagtatgaag
    37021 aaaaattttg tgaaaatagt ttctcacatt tttgcataaa tttggcttaa taccgagaaa
    37081 atggtttttg aacatcactt attcaaaata aaaaaagatt gtgacacgaa ttttgtcaca
    37141 acctttaaat gtattcctag agcaaagaag ctaagcgaag aaatccaatt ctgtttattt
    37201 attgtatttc tttgttcagc atccttgcta aaagcccata ttggacaaag tattcactac
    37261 acccatgatc tcatcttttc gagaacgtgc tttttctgtc ggatcttcta cctcttctgt
    37321 gtcaattcga acaataaatt tccgattcat cgtcacgtaa gcaccgtcgt tgatcaaaat
    37381 aaacagttcg ttctcattat agtctgcaca ggcatctttc catacgtcaa agccgttttt
    37441 ttcagaaggg atatcccgtt taaccacagt ttttccactt aattcgtgga acgttacgtc
    37501 ataatatttc attatctcta cctctttcgt cattcaatat tttgtacttg ttctctgatt
    37561 ttttctaaga tcgtcttaga ctggacgact tgatttttaa tttcgattgc atttgatttg
    37621 gaaccgatcg tgttgatttc ccgattcatt tcttggatca ggaaatctaa ttcccgacct
    37681 acaggacatt gtgcttcgat aagttcatct agtttttgta catggatcgc cagacgatcc
    37741 agttcctcgt gaatatctcc gcgttccaac aagatggcta gctccgtcaa caaccgttgc
    37801 tcatcgactt tcgctccaag aaattcctcc agcttttttt gataccttat ttgaaattcc
    37861 ttttcataga tttctacaaa actatcgagt ttttttagta cttctttgaa ttcttcagta
    37921 ttctttttca acactaaagc taaagcttga ccttcttttt ctcgactcgc ctcaatagaa
    37981 tcaagtgcgc ttttcaatgt atctagagct aactgtgcca attcttccat gctctcttcc
    38041 ggtttttctt ctaccgttac gaagttttcg tccagcacga agcgttccgc catccgacta
    38101 attgacactt gattttgact accgtatcgt tgttgaattc cgtctgtcaa ttgagtgata
    38161 agtgaatcaa tcaattccca gttgatgacg atctgttttt cgtttttgcc aatataagct
    38221 agattcacaa atacttcgat tcgaccgcgg cttaactgct gtttaataag ctgacgaaaa
    38281 tcgttttcaa caaagttcag gattttagga cttcgtattt gaacatctag aaaacgctgg
    38341 ttgacacttt ttatttcaat atctaactga tacgcttttg tttcgcggat ggctttgcca
    38401 aaaccagtca tacttttcat tcgacagggt ccttcctcat tacatatttt ctattgcttt
    38461 ttgcagttgt tcaaactctt cgttcgtcaa tgtcaggcct ttccccattt tttcatggtc
    38521 tggcgcccaa tctcgaagat cgaattttgg cgggcgacca ttccagctga ctaggttcag
    38581 ttctttacgc caccccttgt tgttttctga caatatagcg atttcttcta cgatttcata
    38641 tgaaaattct tgtgccatgg ttgttcctcc ttgagataat ataaatatag gatcagtaat
    38701 gtgtcaactg gttgcttaag caattcatgc tgcaaacgat ccttgcgttt tccttgtagc
    38761 agataatcaa aataaacagt tttcgtgcgc tcattttgta ttttttgctg gtattttcga
    38821 taccttcgcc attcttcagt acttaattga ccaatttgtg ccaataaatc atccggcata
    38881 ctttttatat cttgttggca gatcatttga atcatcatgt ctacttgata gatttcattg
    38941 ggcagtaaaa aatgtttttt tgctaaaagt tctagcatcg ccaatccgca tgtctctggt
    39001 acgaccctgt tcttatataa attacgcagt ttttgccaaa attttatgct tttgaaaaaa
    39061 gataattcta actgaatttc ttttgttaag taagacaaaa atcctcgcca gtatgttctt
    39121 gcaggtttaa cagaatgaaa tgtataccag ttcccatagt aatagcctaa tcgttttttc
    39181 atttccagat agcctaattg taaatttaat tggttccttt ggctatcaaa aagcagaaag
    39241 ctgcctagtg tccacaatgt ttgacatttc caatggataa aaatgtctgg catacgaatt
    39301 tttttcgctg ggcctggccc ttgcacatct acgacaaatg cctctgttgc tcctttgtta
    39361 atcgcaatat caataggtat tttgttgcga tacccaccgt ctgcatattt attttttccg
    39421 atctttcgat aagccatagc gggataaaat gaagcagagg cgagtatcca atctggtatt
    39481 tcttctgttt ttgtctgttg gatatcagtc actacttccg ctagttctgg cagtttagta
    39541 gacaccgtat ataaacgtat tttgggatta tgtttgagta aggacaaatc caaattgtct
    39601 ttgaccatct tttccaatgg agcagaagaa accccgcctt caattagtgc tgttttcgtc
    39661 atttggcgtc tttctcgata gaagcgttca cgaaggtctt caactgcagc catttctggt
    39721 aacgcaagca cttgtcttgt cgacagcttt ttccataaat tcacagcttt tttcatatct
    39781 ccttgtaaaa tcaatgcgcc gttcaacgca cctaccgagg tacctgtgat aatctcaaag
    39841 ttgatatcat gttccttcag cgcctgccac acaccaatct gataagcacc gtgcgctcct
    39901 cctccaccta aaacaagtgc tgtatgatag accagctttt tatttaattg tgtggttcct
    39961 tgatagccgt ttttatgaaa aatacgcaac cattcttctg atagaggaga ttgaaataaa
    40021 aaacaacagt tttctttaat aaaaaaacga gcgcaagctt ccatataccg aaaaaatttt
    40081 ttccattcaa aagtttcacc ttcaatcaac agattattaa aaataacatc tcctctactt
    40141 ttagcaatag taaaatagac ggtatatttt ttcgatactg ctttaaaagc acattgcttt
    40201 tttgcagaac gccaaaaagc gtctctactt tcttgatgac tttgaaaaaa tggaaggggt
    40261 tgttttgctt gctggatagg cgaatacagc gacattttct gtgaaaagta aacttttttt
    40321 atctccatcg cgctctcctt tttcttcaag tataccagta cgtcataaaa aggtcatgag
    40381 tctcgtattc gactttgtag attccataag aaaacaattc ataaaacctc ctttaaataa
    40441 aaaaatacaa aaatcacaaa aattaattga aaatgagagt gttttcaatg aaaacgtgat
    40501 tttgtaatgg aattttaaaa taaaagaaac aagctttttt aatgcaaatg ttgtaaaata
    40561 aaagagatta agaggaaata agaggaggaa catgatgact gagtcagttt atgtacatat
    40621 tgataccaca agtaatgctg ttttaacaaa agggctgact gctactgact ttgcaaacag
    40681 tatcgtgcat tttcctcaaa acttgctctt gcttgatcca tctgcttctg ctggagaata
    40741 tgaatcccat acagggctga aagtaatccg tggtacagaa aatattcagc gtttcttttc
    40801 ctcttctcgt aacaggcgtg gattcgatga attgaagtgg atcgacttta ctgatttaac
    40861 gatgctgaaa gaattgacac ctttagaaat ttcagaatta ttatattttg gtcatatgaa
    40921 aacacatctt cattcgccgt ttttttataa actacagaat aattttgtat acttcgatct
    40981 taatgatcag ctgaatcgga tttattatcg ctatttagat gaattttata ggatttttgc
    41041 tagtaaatta agttcgatct tgtcagataa gatcaatgta aaaaaatctt ttttcaaaaa
    41101 agaaacacct gttgaaaaaa tcagtgtgga attattgaaa gaaatgcgta atttgatgca
    41161 ggaagggatc attttttctt ttgatcaagt tggtttgatc gatggtaaat atcgtatccc
    41221 aatctatgtg attgaagatt atatttggaa attaaaaggc acccggtatc gagaagagga
    41281 aatcatcgct actttaatct actctgtcac cgatcgacac tggcaattgg tagaagatgc
    41341 cgatctttct tatctgccat tgaagtagat ctatttctta tcaaaaaata aaaaggaaac
    41401 aagaaactag gacatgattc tgtctcaagt ttcttgcttc ttttttattt acagctcctg
    41461 tcgtttatct ggcacaaaaa tcgaaggagt cgtttgttgg atccctaata aaacgatgat
    41521 cgttacaata gctgtactca acccgctggc accattcatt acgaaagaaa agagccaagg
    41581 attcatcccc catagtgcat acgctcccca gaaaaccact cctgcaataa aatgccaaaa
    41641 atatctggaa agtgcgccaa tcaatgcacc aaacacgatg ctttttctaa tttgtttcgt
    41701 attatcgtct acatagcctt tttggacatt tgaagccatg agccctgctg cgcctgcaaa
    41761 agtataggca atcgggtact caatcaacac ttgaacgaca cttaaataat aaacttgtcc
    41821 caacggaaaa tgtaggatgc cccaaatgaa acctgccagc atccctgcct ttgtccctct
    41881 tcttaacgca aaaagagtca atggaatctg ccctaatgaa atagaaaaac tgctgccgat
    41941 ctggatcgga atcaacgaca acaccatcgc taacgctgca acaatcgttc cttctaccca
    42001 aactctattt tttcccataa aaaaacttcc tcctttgaat aaaaaagtca caaaggagga
    42061 agcagctttc gaaaatagtc aaacagctgt ttattcacaa ttcctacgct cgcataaccg
    42121 atacaggtac gaagggttta gaaatagatt caatctcagc ccaattggac tcccctttgt
    42181 gagtttattt attatttatt ttttgtttca aacaatggac taactggttt gttttcatgg
    42241 atacgtttga ttgcatctcc cattagtccg ccaacactta cttcatcgat tttgtcgatt
    42301 ttacgatctt ctggaagata gatcgagtct gtaacaacta gacgctcgat agctgaatct
    42361 tctattcttt gtaaagcagg gccggataat actggatgtg tacatgaagc atacacacta
    42421 gttgcaccag cttctttcaa agcattggca gccaatgtga tcgtacctgc tgtatcgatc
    42481 atatcatcga tcagtacaca agttttgcct ttgacttgtc caatgatatt cattacttct
    42541 gcaacatttg cttttggacg gcgtttgtct atgatcgcaa tcggagattt caaaaattcc
    42601 gctaatttac gtgcccgtgt gacaccacca tggtctggtg aaacaacgac aacatcatcg
    42661 cctttgattc ctttttctaa gaaataattg gcaataagtg gcgcacccat caaatgatcg
    42721 actggaatat caaagaaacc ttggatttgg actgcatgaa ggtccaaagt cagcattctt
    42781 gttgcaccag ctttttgaat catgtttgct actaatttcg ctgtgattgg ttcccgtgca
    42841 cgtgctttac ggtcttgacg cgcatagcca taataaggca tgactacgtt gattgttttt
    42901 gcacttgctc gtttcagtgc gtcaatcatg atcagcaact ccatcaagtt atcattgact
    42961 gggctgctcg ttgattgaat aacatagaca tgcgatccac gaatactttc ttcaatgttt
    43021 acttgaattt ctccatcact aaattgagta acagatgatt ttcctaactc gacgccgact
    43081 gctgctgcaa ttttctctgc taatgggcga ttggaattta acgcaaaaat ttttaatctt
    43141 gggtcaaagt aatgttttga catggggacc tccactttct ttttcacaac tctagaattc
    43201 tacctaataa atagtagtca tattttttaa ataaatcaag tgattttgca aaagtcttag
    43261 tttagataag ggagtttttt tgcatatcct tctttattga cttgtcttgc tctcgcaatt
    43321 gccagcgcat attctggaat attgtctgta attgttgacc cggcagcaat cgaactgttt
    43381 ttagctacct cgacaggtcc gatgatattc gtgctagaac caataaagct gtggtcgccg
    43441 acagtcgtat gatgtttgtt ctttccatca tagttgacga agacaacacc acatccgaca
    43501 ttgatttctt ctcccagcgt agcatcacca acataagtca agtgaccgac tttagttcct
    43561 ttgccgattt gagcattttt cacttccaca aagtttccga tatggacgtt ttcgccaatt
    43621 tcagcttttg gtcgtaaatg tgcataaggt cccacatctg catgtttctt gacatggctg
    43681 ctttcaatga ctgagttttc aatgacgacg tgatcctcaa tcctactgtc tacgattttt
    43741 gaatgtgacc cgatgacaca atcagaacca atgactgtat ttccttggat ttgtacacct
    43801 gcttcgatca atgtgtctgg accgatttct acgcctgcat cgatgtatgt cgttgctgaa
    43861 tcgacaaagc ttacgccatt gaccatatgc atctggttaa ttcgctttct catgatctca
    43921 tttgctttag ctaacgcgat ccgatcattg actcccattg attcttcaaa atcatccgtt
    43981 tgataagcag caactgtatg gccttcttct tttaagattt cgatgatatc tgttagatag
    44041 tattcacctt gagcattgtt tgttccaact ttgcttaacg catcgaacaa agcttcgttg
    44101 tcaaaacagt aagttcctgt attgatttct tgtacaagag cttcttctgg tgttgcatct
    44161 ttttgttcca cgattttttc tacgatccca atatggtcac ggatgattcg tccatatcct
    44221 gttgggtttt ctgcttgtgc cgtcaagatc gttgcacttg cattttttcc ttggtgatat
    44281 tcaaaaagat tgttcagcgt ttcagtagtc aataatggtg tatcgccact gataactaac
    44341 gttgttcctt tttttccttc caagaaagaa gcagcttgca aaacagcatg tcctgttccc
    44401 aattgttctg cttgtaacgc atatttactg cgttctccta gttgtgcttt aacttgttct
    44461 gctccgtgtc caacgatcgt aatcacttca tctggtttcg tttcactgac ccgattaatg
    44521 atatgttcta ccataggttt accagaaacg ggatgtaaaa ctttatataa ttttgacttc
    44581 atgcgggtac ctttccctgc cgccaaaata attgcataac gtgcgtccaa ctgcgtcact
    44641 cctaaatata gtttgctgat ttcagtttat cccagtatac ccattttttc aacaaaacaa
    44701 gtgattttct tttatcccag cgttttctgg ataaaaaaat agatagacca taacgggcct
    44761 atctatttgg taaccggtgc tctcctgcca actcctcggt cacaagtcac actactcata
    44821 aaacatgaaa agctgttttt tgaaatcgtt tcttgtgact tagagttaaa cggtaggctt
    44881 acaacctctt cattaaacgt ttttcaatca gctgaccttc ggtattagct caataaacgg
    44941 caaaatatga ggagcaattt ttccgtttat tgagctaata ctcaggacag gacgctgatt
    45001 tcacaacctc tagataaacg gtgttcaaaa gccagtttct cggtattaag ccaaatttat
    45061 gaaaaaatgt ggaaagccat tttcacaaaa tttttcttac tactcgaaac taagcggctt
    45121 tttcacaacc tcttattctg aaaaataatt tcctggcaca accgtaatat ttttcgtttg
    45181 agtatctaca tctttgacat aaagcagtga cgtataatca tcgatggcgc gatgaccgtt
    45241 gaattttgat tcggcaaata cagtgatgcc aacaagttct gattcgaatt cttcaatcaa
    45301 gctcttcatt ccgttgactg ttccgccgcc tttcatgaaa tcatccacta caaggacacg
    45361 tgaaccacgt ttcaaacttc tcttagacag ttccatcttt tcaattcttt cagaagatcc
    45421 agacacatag ttgacactta ctgttgatcc ttctgttatt tttgagtccc ggcgtacaat
    45481 aacgaatggc gcattcagat aataggacac agcttgggca ataggtacgc cttttgtggc
    45541 tacagtcatt acagcatcga ttttttcacc aaggtattta gaagcaatga ttcttccaac
    45601 ttgacgcagc agttcaggtt ctcctaacaa atcagagaga taaacatatc ctcctggaag
    45661 cagacggtct tgttctgata gacgttctgc tagagattca atatattttt tcgcctcttc
    45721 atatgaaatt tcagggatga acaatacacc acctgcagca cccgggattg tttccaaggt
    45781 tccataccct cgttctttaa atgttttctt gatgattccc aaatcttcac tgatagaaga
    45841 tttagcagat tcataacgtt cggcaaagct tgttaaggaa atcaattcat gcgggtgatt
    45901 caataaatac tgtgtcatgt caactagacg ttcactgcga cgtactttca cctattccaa
    45961 ctccttttaa gaaattttat cgttttacat tatataagtt tttcttcaaa aattcgagca
    46021 ttttatgaaa aaataagaaa atagttcggt atttattaaa ataaaaagaa gcctataaaa
    46081 aatttttcgt ttttataagg cttcttttct ttataattta gttatttttt cttctgaagg
    46141 caaccaatat tcgtttgatg atatttacaa tcaggaacaa agcaataaag actaatgtga
    46201 ttgttgctcc tggaggtgta tctagataaa acgagctagt tagtcctgac agcatcccta
    46261 gaaatcctac acaaacactg atagcaatca cgacattgaa gcttttgcct aatcgcatac
    46321 cgattgctgc gggaagaacc atgattgcgg atatcaaaag tgcaccggca atcgggatca
    46381 tcacagcaat agccacacca gtaatcacat tgaacatcat cgacatcaaa tgaacgggta
    46441 gcccatccac gtgggcggta tcttcatcaa aagtcagaac atacatcggc cgtttgaata
    46501 aaaagaacaa tataccgatg gcaacgaata agattcctaa aaagatgact tgctcccatg
    46561 taatggtcac gatcgaacca aacagatagg attggatact tgttgctgaa ttccctccgc
    46621 tcaaattcat caatactaac gctagcgcca aaccaccagc cattaaaatg gcaatggaga
    46681 tttctgaata ggttcggtag atcgttcgca gatactccaa tatcacagct gctaatacaa
    46741 cgactagcat ggtcgtaagt gtaggattaa ggttcaaaaa gaatcctaac gctacccctg
    46801 ctaaagagac atgagaaagc gtatcagcca tcagcgattg tcttctgatc actaaaaaca
    46861 cacctagcat cggggcgatt ccggcaatga agatagcggc aagaaacgct cttctcatga
    46921 attcatatga aagcaacgcc attgagaatc ctcctttctc accagtcgga tctgtctgtc
    46981 cgcatactgt ttgatatctt catgatcatg ggtgatcatt agaactgatt tcccatggac
    47041 atgcgcacta tgtcggagaa gacgataaaa ttcatttctg gattcttcat ccatacctgt
    47101 tgttggttca tcaagaacaa ataagtcagg gtcagtagca aaaatacgcg ctaaactgat
    47161 tcgctgcttt tgtccgccag acaattcacc tattcgccga tttcgcatat cccacatccc
    47221 tacagcttct aaagcacgct gtacatgttg atgatctttt tcagagagac gcttgaacca
    47281 gcggcctctt ggatatcttc ctgaacggac taattcgatc accgtactag gaaaacctgc
    47341 attgaaagat gcaacttgtt gaggaatata accgatactt aatttttttc cttcttgatt
    47401 tttctcagca atctttatca ttccttttga aggtttcagt aatcctaacg atgctttcac
    47461 caaggttgac ttggctgctc cattttctcc agttaaaatg acaaattcac ccgcatctac
    47521 atgataagag acatcttcta gtacaggttc atcatcatag taaaaggtca aatcagatat
    47581 ttcgatataa cgcaccttac aacctccatt ctaaaactta attgatactt tcttttaaag
    47641 ctttcagatt tttttccatg acagaaatat aattttcgcc tgctttgatt tgttcattag
    47701 tcaagctttc taaaggattc aacacttcta gcttcactcc tgtttcattc gacaatgtct
    47761 cagctacctt cgaagaggca ttttcttcaa aataaatcac tttgatgttg tttttcttca
    47821 caaattcttt tagctcagct aagcgacttg gtgtgggttc ctgatctggt gaaacgcccg
    47881 aaatcgctac ttgttttaag tcgtattgat tcgctaaata agcaaaagca gcatgctgag
    47941 tgacaaatgt gcggtttgtt gcatctttta gctcatcgga gtatttttga tccagtgctt
    48001 caagcttttt gatataagca tcggcattct tcgtaaaagt ttccttttta tctggatatt
    48061 tttcgcctaa ttcttcagca atcgttctga cttcttttat agctaatacc ggatcgagcc
    48121 aaacatgtgg atcgtattca tgtgaatgac catgcccttc ttctgattct tcatgttcgt
    48181 ctgcttcttg cgattctaaa cggtcgattc ctttagctgc ttcgatcatc aaggtctgtt
    48241 tgctatccac tgaatccttt aacgaatcca caaaaaattc catgtctgaa ctattataca
    48301 cgaaaacatc tgcatcggaa atttctgctc tttcttttgc acttggttcg aaatcatgcg
    48361 gctccgttcc agcagggatc aaaagtttca cgtttccttc atcccctacg atctcttttg
    48421 taaaatcata catcggataa aaagtcgtaa cgatcgtcaa atcctctttt ttgtctgctt
    48481 ccttgttcgt atttccacat gctgcaaaca gtaaagcacc tatcattacc gtagctgtca
    48541 aaagatattt tttcatttat atgctccttt caatgaacaa atcggaattt tacgatttat
    48601 taacgtgaac taatgtatca aaataaaaaa acacagtcaa tagaaatcca tcaatttctg
    48661 atttaagcat gtatattctt gattaaatcg taaaatggat gagttgctgc tcatatctag
    48721 ccatttcact acaataaaaa actgaagaat accattttag gattcctcag tttttcatca
    48781 cctattttac ttcttatatt ttattgcagg gttcgtacta aataaacttc ctcacaaaaa
    48841 ccttttaacc cattatatac tctctgcgct cttgaataat gttgacacaa ggcaaaaacg
    48901 gttggtccgc ttccactcat caatgcagca tctgctccgt acttgatcat acgctctttg
    48961 atttgatgga tgactggatg ccgctttccc gttatatctt ctaaactgtt tcccattttt
    49021 ttgatcatct gctgataatc ttgctctcgg atggcttcag caagtccgtg gatgtcttga
    49081 tgttggatgg cttgcgtatc tacttctcta aacactgtac gtgtagagac actcattctt
    49141 ggtttgacca acacaaccca gcactgtggc atagaaggta atacttggat ttcttcccct
    49201 ttgccaccga caaatgccgt acttccgtag acacagtaag gaacatctgt accgacttcc
    49261 aaaccgattt ctgccagttc ttctaacgaa cagcccagat tccataattg gttgatccct
    49321 cttagagcag ctgcacagtc tgtacttcct ccgcctaatc cagctgctac tggaatattc
    49381 ttcttaacaa agatcttgac accggttttg atattgtatt tattttttag caataaagca
    49441 gcttgataaa cattgttccg ttcatctacc ggtaaaaatg ctttatttgt ttctacaatg
    49501 attttgtctt ctgttatttc ttcaaaaaat agatgatctg ccaagtctac gctcgacatc
    49561 accatttcca actcatgata cccatcttgc cgtctatata atacatccag tcctaaattt
    49621 atcttggctg gcgctttttc aatcaattcc atcctctcac ccattcgaaa agtctaagtc
    49681 gcaagtattc tatcataggg aaaaataaaa gtatagctta tgtctgccta gtggttgatt
    49741 ttgtcatcgt ttcaacagct ttcacagaat tttctcttca taatccaaac aagttctagt
    49801 gattcttata attctgtgag cacttcttct gccaaactcg gaacatttcc tttttctttt
    49861 cctatcagac tgagtagctg catggtagca aatccgaaat tacttccttt cctataagca
    49921 aagtaacgtc cttcccaatg atcgacatat tttaatttct tttcataagc agactggaag
    49981 gaatagaaaa aattaccata attatatacg atatgcatga ctttttcttg aaagaaagaa
    50041 aaatctgttt ctccaacatt agctaatgga gctaagccta gattggcttc cgagtagccc
    50101 attttctcgt atacaataaa cagattggct aacagatagt cagctaattc ctcagattct
    50161 ttaggtaaga cccgcaacaa atcatatccc gcctgcttct tcgtcatcgg ctgagcggtg
    50221 atgaagccaa cgactttttg atctttacgg acaataccga caccgctaga taatacatat
    50281 gatttatcaa atcgtcccac agagaagtat ttttctcgtg caccttgaag ccatttttgt
    50341 gaaacttcat ttacagcttg atgtaattct tctggcagtt gatcgtacca agtaaaatgg
    50401 tatccttctt tcatcaaacg ttgatattca agttgctgac tcagccgaga caagtcttct
    50461 gttgctagat caacaatccc tgcttcacct actttcgtga agtgaaaacc caattcatga
    50521 agcatcacta cgtagctttc tgatatctta taaaacgcaa gctgatagcc taaacaatct
    50581 gcttgtttca taaactgatt cgttgctgcc cgcatcattt taggatttcc aactggatct
    50641 cctaaaacaa agcatttgtt tcctttgatc tgataaccaa aaacgacttg atcttggtca
    50701 tcttcttggt aataaaaata actgtaacct gacaagcgaa gctgatggct tgtagctgtg
    50761 cctccgtatg tttccaataa acggtcaaaa cggtcttttt cgtactcact gccaagcttc
    50821 gtagtatctt cagctaaata ttgataaagc gccactaaag ctagcaatga gatgcccaaa
    50881 ccaataagcc ctgagaacca cacatcatct gaaggaaaca aaataaaatg gtttcctgtt
    50941 attcgaccga ctaaaaagcg tccgctgtga tagcctgcaa ttgcgtaaac gataaacaaa
    51001 aagccgaaca agctagcatc aaagattata gctccccaag aataaacgaa ttttgttcga
    51061 taaaattctt ttctggataa ccacacagct aacagaatca agacatatac caatatcaac
    51121 tgccaagata acgtacgtgt gattgtattt aaaataccaa aagatagtaa agcaatcgta
    51181 ggcagaaatg cctttttgac ttttactgaa agtgctctag caaggccgag taataaaaag
    51241 ccaaccaata gattcactgt ctgatctaaa aaattgaatg agaacggcaa taatacttga
    51301 aatagccgac tgattgcaga cagattagtg attgttgata gaagtaccat catgattccc
    51361 gcaaaataga cagcacttac gagcacgata tgcgcaacct tttggaaaaa cagtcgcgga
    51421 atgttatcta aaaatcgatt gattttgact cctgtatgtg tgatgaacaa tagaagtccc
    51481 gtcataaaag gtagaacata ataaaacaac cgataatata atagccaaac tactgctaca
    51541 tcttgccgaa cagacaattg actcattcct aagatcatca aaacgtcaaa agtccccatt
    51601 ccccctggga ccatcgtcag cattcctatc aatgtagcaa tcatgaacat aggatagatc
    51661 gaaagcatcg aaatatctat tctcatcaac ttgccgatga tcaaaaatac cgcaagggct
    51721 cccgtccatt gtccaaagga tgccagtagc agaccaagca agccttttgg ataaaactca
    51781 gagaacaagg tctttctctt tagataagca aaaaagaaaa tgactggtgc taaaaaacta
    51841 ccgccgaaaa gccagatcca atagcttcga aaaatacttt ctgactgaat aaaaaagaca
    51901 tcaataaatg taagaaacga ccatacagac aaaccagtca gcataaatag tgcgactttt
    51961 gatacagtgg ctaaaaccat ttttctattt gtctgctttc cataaaaact agctcgcagg
    52021 cttgctccta ccacaccacc aaaaccggcg agattgttga tcgtgtttgt tacccacgca
    52081 gcaagaagaa actcttttct ttccattttt ggttttcctt gtttttctaa gactctgatc
    52141 gtcacccaat catacaacaa catcggagtg acacccagca ttccagccag aatcatgagc
    52201 aggatcgtca tgtggctttg ttgtcccatc ctttgccaaa tatcttgcca actcatgcca
    52261 ttagcaatat ttgcgacttg atttgccaca aagactaaca cggagccgaa aaaaatcagt
    52321 tttaaaatca gactatgttc ctttatccat tgcagcatca agtatcgttt atttttcaca
    52381 ttttcccatt cctaacttgt atacttttgt gtcatacccc aatgttagct tatttatttt
    52441 aatttttcca ctttagacct gttctttgct tgcgatgata gaaaaagaaa gatatcctaa
    52501 tgctaaagga gaggataaca tgaaagtagg atttatcggc acagggaata tggcacaagc
    52561 tattattgat ggtttattaa aaaaaggaac agtctcgaaa gaagaggtgt tcgtttccag
    52621 tggacatttt gaaaatgcac aaaaatttgc tgctgaaact ggcgtccatg catgcaaaag
    52681 taatcaggaa gttgcatcac aatcagatat cgttctttta gccgtgaaac caaaaatcat
    52741 tgaaaaagta ttggaagaac taagagaata tagccagaaa gtcttattca tttctattgc
    52801 ttcaggaaaa tcattaacag atttagaaac agcgcttgaa gatcctcagg cctccatcgt
    52861 acgtgtgatg ccgaatgtca atgtcagcgt aggagcaggc gtttctgcga tttgcaaaaa
    52921 tgaagctgcc acggaggaac agcttcagca agctacgatg atttttgaag caatcggcag
    52981 cgtctatcct ttagcagaat cagatttcag tacattcatt ggtcttgctg gcagctcacc
    53041 cgcattcgtt tacatgctga tcgatgcgat gggacggact ggtgtactga acggtttgtc
    53101 caaacagaca gcaactgaga ttgctgcaaa agcaattatg ggttcttgtc aaaaattcct
    53161 ttcaagtgat aaaaatccat gggaacttgt agaccaagtt tcttctcctg gcggtacaac
    53221 tgttgcaggt gtagttgcct tagaagaagc aggattcatc ccagccgtca tcaaaggaat
    53281 caatacgacg atcgagaaag atcttgagat gttgaataaa aaataatgat agcaatgttt
    53341 tttcgtgcct tacaaaaaaa gaagagctgt ggcttttgcc gcggctcttc ttttgtattt
    53401 tttattattt agcataatca gttgcacgag tttcccgaat aacgattact ttgatgtgtc
    53461 caggataatc cagttcttct tcgattcgtt tacgaatatc acgtactaaa cgaacagcgt
    53521 ctaaatccga gatttcttct ggcttgacca ttacccgaac ttcgcgtcca gcttgaactg
    53581 cgtaacttga ttctacaccg gcgaagctgt tcgaaatatt ttccagactt cttaaacgac
    53641 ggatatagtt ttctaatgat tcacttcgcg caccaggtct tgctgctgag agcgcatctg
    53701 ctgcagctac aaggacagag ataacagaag tagcttccac atctccatga tgagaagcga
    53761 tcgcgttgat tactactggg ttttctttgt acttggcagc taattccgca ccgatctcaa
    53821 catgagatcc ttcaatctca tggtcaagtg ctttcccaat atcatggagc aacccggcac
    53881 gttttgctaa ttggatatct tcgccaagct ctgctgctaa gataccagct aattttgcaa
    53941 cctcgaccga atgcttcaag acgttttgtc cataactagt tctgaatcgc agacgtccga
    54001 tgatcttgat tagatctgga tgaagtgtat gagcaccgac ttcaaacgct gcctcttccc
    54061 cgtattcgcg aatacgttca tccatttctt tacgagattt ctcgaccatt tcttcgatac
    54121 gcgctggatg gattcgtcca tcttgtatca gtttttccaa ggtcatccgt gcgatttctc
    54181 ttcggattgg atcgaatccg gaaagaacaa ctgcttccgg tgtatcatcg atgattaaat
    54241 cgataccagt cagcgtctca agcgttcgaa tattacgacc ttctcgtcca atgatacgac
    54301 ctttcatttc atcattcgga agggtaacga ctgaaacagt cgtttctgaa acttgatctg
    54361 ctgcgcagcg ttgaatcgct aatgataata agtttttcgc tttgcgatct gcttcttctt
    54421 tggcacgctg ttcagattct tttaccatta gagttaactc atgattcagc tcttcttcag
    54481 tcgatttcat gatgatatct cgtgcgtcct cttttgataa accagcaatt ttttctagtt
    54541 ctttttgttg atcttcaatc attttttcaa cgtctttttc tcgctcttca attaattgct
    54601 gttttgaact aagtgcttct tctttacttt caagtgagtt ctcgcgtttt tctaacgagt
    54661 catctttacg attcagcgtt tgttcgcgtt gaatcaaacg attctcttga gattttaatt
    54721 ctaacttact ttctctcagc tcactttcaa cttcagaacg gtatttctga ttttcttcct
    54781 tagcttctaa caatgcttct ttttttagag tttctgcttc tttttttgca ctatcgatga
    54841 ttccagcagc tgatgattgt gcaccagcta tttctttctc gtgacgtgac tttgcgacca
    54901 taaaccctaa accaagaccg acaattaaac cgatgatagc gaggagaatg ttgaatacca
    54961 taaaatccac ctccatacta tctttttcat ttttatcatc tatacagctt ctatgataaa
    55021 ttattctaaa cttgtcaata tgcatcttcg catatatgtg tacaaaaaac atgcacaact
    55081 ttattctaat gtttgtaccc cgtagtgtca actttaaata aacaaagaaa cggctttcta
    55141 cttattcatt aaacgatggt ttttaaaata aatgacacta gtttcatata ggtaaacctt
    55201 taaattgaga aacttttcta ttaaattatt ctttgtagat gaacagatat ttttatttta
    55261 tgtacccact cgtataatta aataactcac gatttcttta ttcaataaaa aaacggcagg
    55321 tcaaggagag tacctactct tcagaccagc cgtttttgtt tatcatgatt tttattcttc
    55381 taaaggcaat tcttcttgtc ctttttcatc ttctgggaca gcgacttctt cgccaatacc
    55441 ataagctgct ctaactagag cagaaacttc tgccatcatt tcaggatgat tagccatata
    55501 gattttagcg ttttcccgtc cttggccaat ccgatcttct ttataagaat accaagcacc
    55561 acttttatca acgatgtctt tttctactgc catgtctaga agttctcctt cttgtgagat
    55621 acctaagcca tacataacat ctacttcagc gattttgaaa ggaggtgcta ctttgttttt
    55681 cacgactttg atctttgtac ggttaccaac aatatctgtt ccttgtttca attgttctgc
    55741 acggcgtact tctaaacgga tcgttgcgta aaatttcaat gcgcgtcctc caggcgtgat
    55801 ttctggattc ccaaacatca cgcctacttt ttcacggatt tggttgatga aaatagcgat
    55861 tgtttttgtt ttgttaatcg aaccagagag tttacgcaat gcttgagaca tcaaacgtgc
    55921 ttgtaacccg acatgtgagt cgcccatttc gccgtcgatt tctgctcgtg gaactaaagc
    55981 ggcaactgaa tcgactacta cgatgtctac agctccactt gatactaaag catcagcgat
    56041 ctccagacct tgttctcctg tatcaggctg tgaaagaagt agttcatcga tattcacacc
    56101 taatttttgt gcatattgcg gatctaacgc atgctcagca tcgataaaag cggcagttcc
    56161 gccatttttt tgtacttctg caatagcatg tagcgccact gttgttttac ctgaactttc
    56221 aggtccgtat acttcgataa tacgtccacg gggataaccg ccgacaccta aagcgacatc
    56281 taacgcaaga gagccacttg gaattgtaga gatttgctgg tcgatttttt cgcccaattt
    56341 cataatagag cctttaccat agctcttttc aatttttttc agtgcagcat ctaaggctgc
    56401 tttacgatca tctgccaata cgataatcct ccttatattt acaaatcaga gcaacatttc
    56461 attatcctta tcatatcttt tttagtgaaa aaaagcaaga aaaaaccgaa caaatattcg
    56521 catttatcat tttcttaaaa gctgttttct caaaagatca aatccttgca taaccgcatt
    56581 atatctgata gcagcacgat ctctggcaaa gtgatatttt tccgaaacca cgccgtcttt
    56641 agatgaaata gcgatccata ctgttcctgc agattgacct tctaacgtgt ccggtccagc
    56701 cactccggtg aaagctacac tgtaatctgt tcttgctatc tcacgtgctt gaatggccat
    56761 ctgctccaca cattctttgc tgactgttcc atattctgct aatagctccg gatcaatctc
    56821 cagaaaacca gcttttgttt ggagcgagta ggtaacgaat ccgcctggaa atacttcaga
    56881 tacaccagca atgtcgccta atgcggcttg gaaggcgccg gctgtcaaac tttccgctgc
    56941 tgttacagtc tgcttgtttt ctttcagtag ttccactacg acttttgcta gcgaattatc
    57001 atcgccgtat ccataaaaat attcccctac tcgttcttgg attttttctt ctaatgctaa
    57061 aagagcttga ttccctgcct gaacatcatt tgttttcact gtcagtcgta atgtcacttc
    57121 atttggtttg gcatatggtg cgatcgttgg attgatctgt gtttcaatca gatcttttag
    57181 ctcagtgacc agtcgcgatt caccaatccc ataaaagcgc aaaactttag aaattagttt
    57241 ttcttcagaa ggaaaacgtt cctctagtaa aggacgtact tgttccacaa acattggttt
    57301 caactcatta ggcggaccgg gaagaaggat atacgcatgt gtatctgttt gataaaaagt
    57361 ccctaaagca agccctgtac gatttggtag aggaatcccg ccttcgatga tctgggactg
    57421 ttgcagattg tttttggtca tttttcgatg ggttgtttca aaatatacca ataatttttt
    57481 gtatccttcc gtattttgta tgagagactt accgaggtga gccgcagttg cttcttttgt
    57541 caggtcatct tctgtcggtc ctaatccgcc acataagagt atgagttcac ttcttgtttc
    57601 agctagagca atcaactctt ctaaacgctg ctgattatct cctacaactg tttgataata
    57661 aacttcgata cctagatcag ctagctgttc tgacaagaaa gtggcattcg tattcacgac
    57721 ttgtcctagt aaaagttctg ttccgacagc tattatttct gctttcatta cttcccgctc
    57781 ccttatatag tatacgctgt atttttatat ttttttattt aaaaagaggg caaggagctg
    57841 tgacaaaagt cttgtcacag ctccttgttc caaataaaca gtgttctcct gccaaaacct
    57901 cggtcataag tcacaatata cataaaacat gaaaagctgt tttttgaaat tatcccttgt
    57961 gactcagagt tagacggcag gctcacaacc tctccactaa acgatactta cattgatcct
    58021 ttgaacacac cgctgttttt gatgaagtaa tccacacctg aatagatagt aaagatcaga
    58081 caagcataaa gcatgatttg atctactgga ataccgatca ggctgaatgg gatattattg
    58141 ataaacagca agataatagc aaccatttgt gtagccgtct tgacttttcc cggccaagct
    58201 gcagccatga cttctccatg ttcgacaagt agtaaacgca agcctgtgac ggctaattca
    58261 cgacagacaa tgatcgctac tacccaacca ggggcctttc cttggtcaac caacatgata
    58321 aaagcagtca taactagcat tttatctgcc aacgggtccg caaacttgcc aaaattagtg
    58381 acaaggcctc gcgcacgggc aatttttcca tctaaccagt ctgtgatact agctaaagca
    58441 aaaataactg cacctactag ctgtgtgaca gccagtgtgg tgtctcctac gttaagttgt
    58501 ccccaatcta aaggtaaacc tacaaccaaa atgaaaatcg ggatcataca aattctaagt
    58561 acagttaatt tatttggtaa attcacacta tcgactcctt tcttccctat tctacgtgac
    58621 tatcagcgaa gtttccaccg atattattta cttttccaaa tgaatttatt caagggagta
    58681 tttttattga aattgatctt tttgaattaa cgaagaagga tcgcgacaca gatttgtcac
    58741 gatccttctt ttttatacct gcaagtaaac agatgcgtaa actaatttat acgatcactc
    58801 tgcgtattga agagtaaggt tcacattttt tggactctga ttgttttccc ctggattaac
    58861 tggtacggat tctccattcg ctttgatcgt tgcattgctt gctgcaccaa tcgtgatggt
    58921 cgcatttgtt gctgtttccg gtaacacggt actctgtgtt tcatttgctg ccagtgtccc
    58981 ttgataaaca taggcattgt ctactagcac acctaaccat acacgattga cagcagtaaa
    59041 ttcaagggtt acaggcttgg tagcgtctgt gatatttact gcgatggcac tgccagaatc
    59101 ttctcctgta gctattgcca ttttcttttc ttcacttgat tttgttgttg attctactgt
    59161 agaagactct ttggtctgcg tgctttgctc tgaggaagag gactcctcga ctgatccttc
    59221 tactttaagc gaagaagctg tgtctccgat tattggatca gcttgacgat cttgccaagt
    59281 catatagccc acgacaacga caatcgccaa agcaaccaat cctaataaaa tgacaggaag
    59341 acttgtccaa aagcgacttg gatgcgattc ttcctgatgc attgcttttc tagaagtact
    59401 tactgtttca ggctgcggac gttcagggac cgatcctgtc aatttgcttt tcccatcaaa
    59461 aacatcgact aaatggtctc catcttctcc tacagcttca gcgtattgcc gaataaatgc
    59521 ccgcacgtaa aatttaccag gcaattggtc aaaatcatca ttgtcgattg cttccaaata
    59581 acgtttttga atttttgtaa tctgctgtaa ttcatctaaa gatatttttt tattcaggcg
    59641 tgcttgccgt aatttttctc cgatggtttc aaaagccact cgttcatctt ctccagtctg
    59701 tttgattctc cgaagcatct gctgttgcaa cgaaagacgt tatgtttggg tgctgtgaca
    59761 aaagtcatgt cacagctcct tttttccgaa taaacattgt tctcctgcca actcctcggt
    59821 cacaagtcac aatatccaat aaatataaga agctgttttt tgaacttgtt ccttgtgact
    59881 cggagttaaa cggcaggctc acgacctctt tcttaaacgg tgttcaatca gctgttcctc
    59941 ggtattagct caaaaaccgg caaaatataa ggagatattt ttccgtatgt ttctctaata
    60001 ctcaggtcaa aacgctgatt tcacaacctc ttccttaaac ggtgttcaaa agcttgcatc
    60061 tgcggtaata agtccaacca agttaaaaac attaagaagc tgtttttact tggctgttct
    60121 tattacttga tgcagggcag ctttttcaca acctcttggt acacggtgtt ccagaagtag
    60181 cttcttcggc aataagccga aatatcacaa aaatttgaga agcaattttc gtaaattcct
    60241 tcttatttct tgaagctgac cacttctgtc acaacctctt tgattacttc gtttgatttt
    60301 attttaatat aagttgatta aaagagagca tgatttgttt tattttctca ctaatttttc
    60361 caacacaact aagaatacca taaaagctga ttttggagga ggttcctact acaagtctaa
    60421 aacgaaattt aagacttttc ctcataaaat actggtttat tttggtctca tgtaaaactc
    60481 gctgaaggcc tcttcactta taaatgcttc cccagctgcc agtacgtctt tcatttggat
    60541 cgaatcgatg atttcaggaa gatcaaataa agttcgatcg ccaaataaac tttgcgtaaa
    60601 ttgattggca atatattcga tcgaatttaa tgattggaaa tattgtccaa gcattttctt
    60661 cttcagcaaa tcgagatttg tttctgacac ttccggatca tcagcgaatc caagaatgat
    60721 ttctttgact ttttctgctg ctttctctgg ttcgtccgta tctccgctga agtccgcaaa
    60781 gtgaaattca cgatccaagc tgaattcaaa accaaagctg tcatcgataa ttccttgatt
    60841 gtacatcgct agatagtttc gagaagtatt gcctaaaatc atttggaaca acagattgat
    60901 tgctgtttta tagcgtaaca gttctgttcc ttcttgcggc aatgtgtcta atcctttaat
    60961 accaagtaca aatttatctc gtgtaatggc tgcttccaat gcactttgtt tgatgatttc
    61021 ttttgtgttt tcagggaaat aacgtacaat ttcttgcttt ggagggaaat tttttgcttc
    61081 ttggttttcc cgaataagtt tcatcaattt ctcaggctcc atcttaccaa ctacaaataa
    61141 aaccatattg cttggctgat aaaacgtccg atagcacgta tacaagtctt gagctgtgat
    61201 tttgtcgata ctttcaaccg tgcccgcaat atcgatatgc aatgggtgtg taggatacaa
    61261 gttatttagt atgccaaaaa acatccgcca gttagggtcg tcttcataca tttggatttc
    61321 ctgaccgatg attccttttt ccttgtttac agtttcttct gtgaagtaag gtgcttgtac
    61381 aaaatcgatc agagtcgtca gattcttttc tacctgatcc gtcgtagaaa acagatagct
    61441 ggttttcgta aaacttgtga aagcattggc ggaagctcct tgtttcccaa ataattgaaa
    61501 gacatcacca tcttcttttt caaacaactt atgttctaaa aaatgggcaa ttccatctgg
    61561 aactttcacc ttttcttttt caccataggg aataaattcg ttatcgatcg aaccataatt
    61621 cgtactgaac aaaccatatg tcttgtgata gtcattttta ggcaacaaat acacggtcaa
    61681 accgtttggc agtacttcat gataaagtgt ttcattgatt tgctcatatt ctgttttatt
    61741 catttgcatt tcctcctgct aaaaagaaga ttgcctgcaa ttcgatttgc tcagctactt
    61801 gttgtatctc tttgatcgtt acgctctcca tacgtttcaa ccattcttca tcagataatt
    61861 ttgtttccgg cagccagctg tccaaaaaag aagcttcgat tgccgcttgc ggagagtcta
    61921 gagaaagcag atattggttt ctcagcattg cttttgtctg agacagttcc aactctgtta
    61981 tttcaccatt tcgcaaactt tctaattgct cgtgaatcag atgaagtact tgatttcggt
    62041 tcttttcatc gataccggtt tggacactca tgaatcctcg gaacgtatcc acgctactag
    62101 aggcataata agctagactt tctttctctc tgacattcat gaaaagttta gagtgaggaa
    62161 aaccgccaaa taaaccgtta aagaccatta gcgcaaaacg ttctggttca tcgtaataca
    62221 catttgtctg ataagctagg ttcagctttg cttgaacgat tggctcacgt acttgtcgtt
    62281 ccttcacgat attcacttga ggttgggtat aaaacagatc tggataaact gtttcccgcg
    62341 actcaaatgg taattgccca actgcttcag ctgctttgtc cggatcaaca tcgccgacaa
    62401 caaaaatgtc gatttgatca tttgccatca tttcttgata gtaggacgct agcgaactag
    62461 cagtgatctt gtccaaatct tcgactacgc ccaaccctgg gatcttttgt tccgggctgt
    62521 tttcaaaata aagttcttgc aaggcatagg aagcaaaagt ttgtttatct tccttcaaac
    62581 tttccaaata tagacgcaga ttgttctttt ccaagtcaaa cgtcaactga tcaaactgat
    62641 gatttttaat atttggataa aataaaacct cttttaaaaa atctaccgct tgagaaaaaa
    62701 ggtttggatc attgacatat tcaccattca caaaactgat ccctgcgttt agccaatgta
    62761 aatttccttt ttttctaact gataatccaa agcttgcgcc ataaagctct gcaagttgcg
    62821 cacttaactt tgtctgatcc gaataattca aactatttgt ttccaacatg ctgctgagaa
    62881 gtgaacgttt cgtgatgact tcttgttgca gacgcgcagt aaaacggata aaaatccgga
    62941 tcgttttgta ttgttttgtt ggtaagacat gaagattcac gccttctgcc aattgataca
    63001 ccatatttat atgctccttt tcacagttga ttgcccgctt actcttttaa tgggtcaacc
    63061 tgcctttttt acttattcct ctgcttgaaa tttataagtt caggcaattc gccgtttttt
    63121 ctaaatgatg ttacacttta tagtatagca tagatgtttt ttatcaaaag aaacagacgg
    63181 ctaaaagcgt atattgtttt tttatttttt atttttcgat atactaaaga caaataaaag
    63241 aagggagggt cattcatgat caaagaattc aaagagttca tcatgcgtgg agatgtcttg
    63301 gatcttgctg tcggcgttgt tattggtagt gcgtttacaa gcatcgtaaa ccaagtggtg
    63361 caaggcttga tcacaccact aataggttgg tttgtcgcaa tgatcacagg tacttctgat
    63421 ttagaaggag cactttcaat tcttgactgg tcgccgacaa aaggcgtcac atttgcgttt
    63481 ggtaacgtta ttagtgctat cattacattt ctgatcactg gttttgtctt attcttagtt
    63541 gtcaaagcgg caaaccgtgc gaagaattta cgctccaaag aagagcaagt ggaagtggaa
    63601 gaaactccta ctgcagaaga ttatcttagt gacatacgcg atcttcttgc caaacaagtg
    63661 gcagaagaca atacacatcc agtagagcaa acaaatcttt ccgatacttc taaataataa
    63721 agaatctaaa aaaaagaaag ccgattttca gtgtcggctt tcttttttta gattcttaac
    63781 ttgctacttg ttcctttttc atgtcgatat gtggaatatc atcttccaaa tacacatctg
    63841 agattgcctt gaatccaaac gactcataaa aagcttgtag gtattcttgt gcgccgatca
    63901 cgattggttt ttctggaaaa tttttctgga tcatgttaat cgtttcttga acaatctttc
    63961 ttcctaaacc atctttacgg ttgtcctgat gaacaaggac acgtccaaaa tggatactct
    64021 ccgcttcttc atatactcgc gtgtaggcaa ggatcttccc atcagtatct tgaaaaaacg
    64081 tatgccaagc ttctccatca atgtcatcaa cttcttgata aggacactgt tgttccacaa
    64141 caaaaactgc gattcgttct ttgacgatcg cgtaaaactc tgctgttgac aattcttcaa
    64201 atttctttac ctgatattcc actaagcaaa cgccccctgc ttttttattc ttagcatacc
    64261 gattcgcaca caaaaaagca aacgaacctt acgaatctca ggctcgtttg ctttttaaac
    64321 tgcttcagtt aaaaattcga tctcaactgt ccgagtaagt acatctgaat agctgtaaga
    64381 tactcgttca aaagaatttt cttcaggatc caaatcaaca acgaatactg aaggataggt
    64441 ttctgttaaa acgccgcggc gttctgtttg acgctttctt cctgtctgag caaccaacat
    64501 gattgggctg ccgatacgac cttctaaatc tttcttgatt gaagctaaag ttgttggcat
    64561 acagttcacc tctactatca actataccac atatttttaa aattttcaag tttaccataa
    64621 aaaaaaaaga aatgcaataa aaataaataa gaagctcatt aagatttttc taaattattc
    64681 ctcattataa aatttcaagt gtttttttat tttgagtttt actctcccgt aagcgctcat
    64741 tacttgcttg tgatccattg ctaaacattc agccatgtct acaaaatcaa cgccttgcat
    64801 ataataatga aaaattttag cttctatttt tgaaaactgg atttcgcaat tttcgattgc
    64861 ttcttttaat aaaagatgct gaattgctaa aggttcttgc aatgtgatct ctgctaaaaa
    64921 gtctggtcct tctgtctcta ttttttggtc gattgagact tcatcttttt gatcacgacg
    64981 cttcagcgcg ttctgcttcc tcaacagaga atagatttga ttgcttataa cgcttttata
    65041 ataacttcca aagctaacac ctttgctttt ttcgtaagtt ctcaatgcct gatataaagc
    65101 gatccttgct tcttgttccc aatcctcaga aacataattt cttaaataat aggtgttttt
    65161 caaacgtagt aaaagtggaa aatatttttg atacagggca gcaaatgctt cttcgtcacc
    65221 attacgtgca gcgcgcaata actcctcaga cataaaataa ttcctccata aattcgttta
    65281 tggaggaatc ttatcatcaa tgattcatcg aactgattag aacgatatgt tatttatttt
    65341 ttctcattaa atcgtccaat ttttgggaca atttttttaa ctgctcttca ttccatggag
    65401 aattacgtcg gaaatcaata aaatgcatat ctttattttc ttgggctatt gttttttccg
    65461 ttttttttat cgtcttatat aattcataag cagaagttcg taatgctcct tgggaaaaga
    65521 tcatccactg ttctgctaaa tcgcttgtcg ccactgtcac ttgtgtcaaa cggtcattca
    65581 gctgaccagc gattctctcg atataactgt cagccgtttc gtcttctttc gtaaaaacaa
    65641 catccaactg gtatttctta taattttgtt ggatgcccgg aactagttgg gcatcgaaga
    65701 caacgatgac ttccattcct tcatatttcg cataatttga taaacgatgt aaaagagctt
    65761 ctcttgcatc cgccattttg tcctgctttt taagctggac aagttccggc cacgaaccaa
    65821 tcatgttgta gccgtctaca atcaacagct gttttttcat ggtctactcc ccctgacgtt
    65881 gggaaaaagc ctgatacata agcaaaccag cagcaacact ggcatttaag ctctggacgt
    65941 gcccggtcat cgggatcgtc agcaattcat ccatttcttt tttcaatcct ggactcattc
    66001 ctttgccttc attaccaatg actaaagcaa ttgatccttt ggcattccat ttttggaagt
    66061 ttgtgccggt catatctgtg ccaaataccc aaaatcctgt ttctttgagc tgttgcacag
    66121 cttgtaccaa attcgtcacg cgtgcaacag ggacatgttc gactgcccca gtggaagtct
    66181 ttgttacgat aggtgtgatt ccaactgctc ggtgttttgg tatgatcaca ccatcgacgc
    66241 cacttgcgtc tgctgtccgt aaaatcgacc caaaattgtg tggatcttcg atgctatcca
    66301 aaatcaaaaa gaaggggtct tcttttttct cttttgttcg ttcaatcagt tggtcaaggg
    66361 ataaatattc ataaggtgta atcgcaagaa cgactccttg atgcacgccg tgatcgctca
    66421 aagtttctaa tttttgttta ggaacccatt tgactggcac agcttgttca cgtgcgattt
    66481 ctttcagttc ttctactttt tctcctcgtg aatcttcttg aagaaagagt ttattccctc
    66541 gcccttgttg tagcgcttct actgcggcat ggtgcccaaa gacgaaatta tcttctaatg
    66601 cttcttcatt ttgatcagaa actgactgat ttcgtccagt ttgcttttta tttgaatatc
    66661 tattttgttt tttgtcttca aatccacgtt tcgattgatg tttgtttgtt ctttctttac
    66721 ccattttttt caccaacttt ctgaatacac cagcggatca attcttccat ccgctcggtt
    66781 tgttttgtca aatgcagata gcccatgagc gcttcgaacc ctgttgcgac ccgatacgtc
    66841 gtaacatcag cattttttgc gctcgtatgg cttttagcat ttcttcctct gcgataataa
    66901 agttcttctt cttctgtcaa aagatgttct tccagcattt gctgaatcaa aaaggcttgt
    66961 gcattcgcag aaacataatt cgttgccgca cgatgcagct tattgggttt tgtttctcct
    67021 tgatcaatca ggtggtcacg aacatagatt tcgtaaatcg catctccaac ataagccaag
    67081 gctaaaccgt tcaattgtgt gtaatctctc atgcttctct tctccatcgg gttccttgcg
    67141 gtgtatcttc taataagatc cctttttctt tcaacaaatc acgaatttcg tcgcttcgga
    67201 caaaatcacg attgcttctt gcttgatttc gttcttcgat caattgttca atctcttcat
    67261 ctaataactc ttctgctgta aataaaatac cgaagatcga aagccattgc gagaataaag
    67321 cttctccttg tgccaagaca gcggcagaaa ctttcggctg gtctagataa gtgttcagcc
    67381 acttagcaag ctcatagacc actgtgatcc catttgctgc attaaaatca tcgtccattt
    67441 cttcgatgaa tcgctgttct aaattttcta acaaagcgat tttatccgca tcatctgcca
    67501 aattctctga ggcagtttct tggcggaatt tcaaattgtc aaacgtattc ttcagtcgtt
    67561 gtaaattggt ggctgcttct ttcatcgtcg tttcactgta gcggatcgga cgacggtatt
    67621 gtgtggtcgc catgaagaaa cgcaagactt gtggatcaac gtttttgatc atttcatgta
    67681 cagtgatgaa attccctaga gatttactca ttttttcatc gtcttcgcca atcgttacat
    67741 agccattgtg catccagtaa ttagcgaatt ttttccctgt tttcgcttca ctttgtgcga
    67801 tttcattttc atgatgagga aattctaaat cttgcccgcc accatggata tcgatcgttt
    67861 ctcctaaatg ttttgttgcc ataacggaac attcaatatg ccaaccggga cgtcctttgc
    67921 cccatggtga atcccaagaa atctcgccag gttttgcttg tttccataaa gcgaaatcta
    67981 atgggtcttc tttttgctgc tgttcttccc ctgtacgctg acttgctccg acttccagtt
    68041 catcgatgga ttggtcactt aatttcccat aattttcaaa tttacgggta cggtaataca
    68101 catcacctga agattcataa gcatagcctt tttcaaccaa cacttgaata aatgctaaaa
    68161 tatctggcat atgatccatg actcttggat gcagtgtagc aggttcgaca ttcaacgctt
    68221 tcgtatcttc ttcaaatgct cggatgaaac gatcagcaac ttctggtgct gtaataccta
    68281 attcgtttgc tgtacggatg attttatcgt ctacatccgt gaaattcgat acgaaatcga
    68341 ctttatagcc tcgatattca aaatagcgtc gaattgtatc gaaagcaatg gtgctacgag
    68401 catttccgat atggatataa ttatacacag tcggtccgca gacatacata ccgacatgtc
    68461 ccttttgtat agggatgaat tcttcttttt ttctggtcaa tgtattgtag atttttatca
    68521 ttctgatctc ctcacttttt ctcctttgat tcgaacgact tttgctggta ctcctaccgc
    68581 tgtagcgtcg tctggaacat ctttcaacac aacggcacct gcaccgattt tggcgttttt
    68641 tccgatcgtt accggtccta atatctgcgc attcgcagag agcatggctc cttgtttaac
    68701 agttgggtgt cttttacccg tttcttttcc tgtgccgcct aatgttacgc catggaataa
    68761 aatcacatcg tcctcgattt ctgcggtttc gccaatgacg attcccattc catggtcgat
    68821 gaacacgcca gttccaatcg ttgctcctgg atggatctca acaccagtta ggaaacgcca
    68881 gaattgagca ttgatcttcg ccaataaaaa gagccggtgc tgatataaaa aatgagagaa
    68941 acgatgccaa aacaaggcat gaaaaccagg gtatgtcaaa acgatctcag ctgtcgaacg
    69001 tgcagccgga tcgtttctct ttgctgcatc aatcgctcgg gtaaaccaac tcatgacttt
    69061 ccactccttt cgtaagaatt ttatgtagga aatcatcttc ttataaagaa aagaagcgcc
    69121 ttttaaataa gtttccttat caaaagacgc tttccgcgtg gttccacttt tcttcataat
    69181 caatgattat ctctgacagc taacgcctgt tatacgttct tggctacttt gtttcctata
    69241 aaacagtttt tcctgttttc tgtgtttcgc caagaccact cccagaggca tttcggcaac
    69301 cattcattga taccttgcac cacccggtat ctctcttgta atgatcagct gcttactttt
    69361 ttctgttcat cgtgtttagt tcagtacttg atttaaatgt gctaatgatt tttcacgacc
    69421 aagcaattcg atcgtttcag gcaattctgg accatgcatt tgtcctgata cagctacacg
    69481 gattggcatg aaaagatttt ttccttttac gccagtttct ttttgaacag ctttgatggc
    69541 agctttgaca gttggagcat ctactacttc catttgttct agctgtgctt tgaatgcgtg
    69601 gagaacagta ggaactgttt caccagcaag tacttctttt gctgcttcat tcaatacagg
    69661 atgttcattg aaaaatagcg tagacagatc aacgatttct gcagcatagc tcatttgagg
    69721 ttgatacagg ctaacgatct tcttcaccca ttcgattgtc ttttcatctg ggttttctgc
    69781 tacacgtcca tcagcgatta gataaggcag acacatgtca gtaaatgcat ctagatccat
    69841 tgctttgatg taatggttgt ttacccattg cagttttttc gcatcgaaag ctgcgggtga
    69901 tttacttagg cgttttggat cgaacatttt gatcaattct tggtgttcga agatttcgtc
    69961 ttcgcccaca ggtgaccagc ccaataatgc aataaagttg aacattgcat ctggtagata
    70021 gcctaattcg cgatattgtt cgataaattg caagattgat tcgtcacgtt tgcttagttt
    70081 tttacctgtt tcactgttga tgatcaatgt catatgtccg aaggttggtg gtgtccagcc
    70141 aaatgcttca tagatcatca gttgttttgg tgtattggca atatggtcat ctccacgtaa
    70201 aacgtgagtg attttcatca aatgatcatc gaccgcaaca gcaaaattat aagttggcat
    70261 accatcgcgt ttttggatga caaagtcgcc accgatatta tcggattcga acgaaatagc
    70321 gcctttcacc atatctgtaa atgcgtattc tgtattgcga ggcacacgga aacgtacaac
    70381 agattctaga ccttgtgctt ctttttctgc ttgttcttca ggtgtcaagt tcgcacatgt
    70441 tcctgcgtaa tgaggcattt ctcctcttgc gcgttgtgct tcccgttctg cttctaattc
    70501 ttcttctgtg caatagcatt tgtatgctcg attgctagca agcagctgat caatcagcgg
    70561 ttgatagatt tctttacgtt cagattgacg gtaagggccg tattctccag gattttcagg
    70621 agattcatcc caattcattc ccaaccaagc aaggttttcc aactggcttt tttcgccatc
    70681 ttcgatatta cgtttttggt cagtatcctc aatacgaata ataaagtctc catcattgtg
    70741 gcgggcaaac aaataattga ataatgcagt tcttgcattt ccaatatgca ggtgcccagt
    70801 tggacttggt gcatagcgta cgcgtacttt cgtcattttc ttcctcttct ttcaaactag
    70861 actttgacta acagcaaaaa ttccgtcagt tacggcttct caaatatcat ttatttaaag
    70921 ccactcagca caaattttac cttttctaag gtaaatagta aagccaactg gttgaatttc
    70981 cttaccagtt ggctgaattt cttttttatt ttgattgttt agtctttttc tctgtctctt
    71041 ttttattgtc gattcctcgt cctgcatgtg caggtttagc aaagatcatg cgtccagcag
    71101 ctgtttgaag ggcacttgtt acaacgactt cgatacgttc attcatgtaa tgctgtccat
    71161 cttctacgac aaccatcgtg ccgtcatcaa ggtaggctac tccttgttgg cgttctgtcc
    71221 cggcttttac tactagaaca ttcatcgttt caccagggat gacgactggt tttacggcat
    71281 ttgccaacgc attgatatta agaacaggta cattttggaa ttcagagact ttattcaagt
    71341 tatagtcatt ggttacaatg acaccatcta aaagcttagc caatttgatc aatttgctgt
    71401 ctacttcact gatatcttca aagtctccat cgtacatttc gacagatata ccctcttctt
    71461 tttgcaaggc atttaggata tctaatccgc gacgaccacg cacacgtttc aaactatccc
    71521 ctgagtccgc gatgtattgt agttcgtaaa gaacaaaatt agggatcatc aaggttcctt
    71581 ctaagaatcc agtctttgta atatcataaa tccgaccgtc aatgatcacg cttgtatcca
    71641 agattttata tttatggaaa ttttctcctg attttcgttc taacagttga ctctcaactt
    71701 gactagctgt ttcttgctcg atttttttgc ttcgtgaacc aaaaactttc ttccattctt
    71761 cgattcgtgt cgttcccatt ctcaatccca gatagcctaa gatgatcatc agtaaaatcg
    71821 gcaatacact attgacgaat ggaatttcca tattgtaaag aggggtcgag atcacaacac
    71881 ctaaagtcaa tccgatgatc gcaccgatcg caccgaagag aagataagtc aagctgacct
    71941 cacttagttt ttgttctact tgtttgataa tagctgagat atgtttggcc aacagcaaag
    72001 ataataaaaa gaaaataagt gcgcctaaca ggctgttggt aaatgtatta ttcagccatc
    72061 cgtttgactg ttgaccgatt gcctgccaag ctgagggtaa aaatgaaata cccaagcttg
    72121 cgccgacaat gatcatcagc aaagtaatga cacgtttttg catcgttttt cctccgtttc
    72181 gacaatcatt tattagttag cggaacacac gcttcaacgt ttcagccaaa gttgctactc
    72241 caactatctc gattcctttt ggcgcttccc agttacctaa gttgttttta ggtaggtata
    72301 cttttgtgaa gccgagtttt tggacttctt tgactcgttg ttcaatatga ctgacacgtc
    72361 tgatttctcc agtcagtcca atttcaccga tgaaacattc cgttggctgt gttccttttt
    72421 ctttatagct tgaagcaata ctgacagcga tagctaaatc aatcgctggt tcatttaatt
    72481 ttaccccacc tgcagctttt aagtaagcat cttgattctg aagaagcaac ccagctcttt
    72541 tttccagcac tgccatgatc agagataccc gattgaaatc aagacctgtt gttgttcgtt
    72601 tggcatttcc gaacatagta ggtgtgacta atgcttggat ctctaccaaa attggacgtg
    72661 tcccttccat tgccacaacg atagcagagc cagttgcacc gtctaggcgt tcttctaaga
    72721 aaatctgtga aggattagcg acttcttcca atccatgctc atgcatttca aaaatcccaa
    72781 tctcattcgt tgagccaaat cggtttttta ctgctcgcaa aatccgaaaa ctatgatgtt
    72841 gttcaccttc aaaatataac accgtatcca ccatatgttc taacattctt gggccggcga
    72901 tcgagccttc tttggtaaca tgaccgacga taaaaatggc tatcccattt gttttagcgg
    72961 ttttgagtag ttctgcagtg gtttctctta cttggctgac acttcctgcc acacttgtga
    73021 tgtctggctg cgtcatcgtt tggatggaat caatgataac ataatcaggg gagatatgtt
    73081 cgatggcacg actgatttcg ttcatatctg tttcagcgta tagataaaat tctgtgttga
    73141 tacttccgag gcgttccgcg cgtaatttta tctgctctgc gctttcttcg ccggatacat
    73201 ataagacttt tccgcctatg gctgctaatt gctgagaaac ttgtaacagc aaagtggatt
    73261 tcccgatacc tggatcgcca ccaatcaaga ccatagaccc tggcaccaca cctccgccta
    73321 acacacggtt cagttcttct aattttgttt tgatccgagg ttctttttta gggacgacgt
    73381 ctgcgatttt tgttggtttt gctttttctc ctgtcaaact tgtccgagtt ctgcggtccg
    73441 ttgtatcttg ttcgatttct tcgaccatcg tattccattt tccgcaattt gggcagcgtc
    73501 ccaagaactt aggcgacaca tacccgcaat tttggcaaac aaattgtact tttgattttt
    73561 ttgccattgt accgcctcct tttatcctaa tcatgagaca ttaaatcaag cttaagtatc
    73621 tttaacgttt tatttactgg aagaaccaaa tccgccttga cgttgagcag tcgtttgatc
    73681 ttgatctgct tttaaaaacg gcaaaaagat cccttggccg atacgctcgc cttttttgat
    73741 cactacatcc ttgaaaccaa agttggtgaa ttggaacatg atatggcctt catttgcctc
    73801 attattgtaa taatcactgt caatcacacc tactccgttt gtcaacacta aaaaccgctt
    73861 caacggattg cttgaacggt tagcaagctg caaaaattca tcttctccca tgtaagcttt
    73921 gattccagta ggcacgaggg ttggtttcaa ttgtttttca ttttctgata catctttttt
    73981 caatccatct gcgactgttt ccaacccctt tttccagcct gctttccaga tacttggaat
    74041 cacgacctct tctgctgctt caaaatcata gccagcagca tgatgtgtag cgcgctgcgg
    74101 tagattgata ttttgatctt tatatttaga aataacttca aatcctcttt ttctcaccgg
    74161 ttttcctccc taaataaact actcctattc taacatatcc gaggctgtaa aagactttct
    74221 ttacaaattc ttcaagaaat tctgctatct taaagtaaac cattaattcg ttctttttcc
    74281 aaacgactgc aagttgtaca aaaaaactat tttttacatg actttactcg tcaaaacaag
    74341 tagaatagaa cgaaattaat gagtggatat ttgattgagg tgtcacatgc gtaaagaaat
    74401 taaaaatgca aaacgaatta ttgtcaaagt aggaacaagt acattgattt atcccaatgg
    74461 aaatatcaat cttgcggcaa tcgatcagtt agcttttgtc ctttctgatc ttagaaatcg
    74521 gggaaaggaa gtgatcttag tctcatcagg agctgtaggc gttggtatgc ataaattaca
    74581 tttgtcagaa cgtccgactt tgattcctga acagcaagct gcggcggctg ttggtcaagc
    74641 cgaactgatg aatatctata atcaaagatt cagtgtatat aatcaacaga cggcacagat
    74701 cctcgtgaca agagacgtgg tagattatcc tgaaagtcgt aaaaatgtga ggaatacatt
    74761 ggaacagctt ttgattatgg acacgatccc tatcgtgaac gaaaacgata ctgtagcagt
    74821 ggatgaatta gatcatctga caaaatttgg cgataatgat cagctgtcag ccatcatggc
    74881 aaaacttgtc gcggcagacc ttttgatcgt cctttctgat atcgacgggt tttattcaga
    74941 taatccgact acaaatcccg aggctcagat gtatcgctat atcgataaaa tcgatgaaaa
    75001 gattctggca caagcaggtg gtgctggtag cacatttgga acaggcggta tgcagagtaa
    75061 attaaaagcc gcttctagga tatttgaagc aaacagcgca atgattttag caaatggaaa
    75121 aaatccggca attatttttg atattcttgc aggaaaagaa gtaggtactt tatttaagga
    75181 ggacttgaaa tgactgactt gatgcaatta ggacaacagg caaaagatag cgcgcaacaa
    75241 ctagcactta tgcctacaaa ccgcaaaaat gagctacttg ttcaaatggc acaaaccatc
    75301 aaaaagaatc aacaagcgat cattgaagca aatcataaag acttagaaaa agcagtcgaa
    75361 aacaatatca gtgaaacgat gcaagaccgc ttgcagctga cacctgagcg aatcaatgcc
    75421 atggctacag agatcgaaaa aattgcttcg ttagacgatc ctattggaaa agtagatgag
    75481 atgtggacga acaccgacgg attgagaatc ggcaaaaagc gcgtgccact aggcgtgatc
    75541 ggcatcattt acgaatctcg tccaaatgtc acgacagatg cagctagtct agcattcaaa
    75601 tcagggaatg ccgttatcct tcgcggtggc aaagaagcat tcttctcgaa tcaattatta
    75661 gtccaattat tgcagcaagt actggtcagt gctggcgaat ctccttatgc catccagttt
    75721 gtcgatgata cttctcatga aactgcagga cagttgatgc gattgacaga atacttagat
    75781 gtgctgattc ctcgaggcgg agcaaaatta atccaacgag tcaaagaaca ggcaacggta
    75841 cctatcattg aaacaggtac aggaaataat cacgtatata tcgataaaga agcacagtta
    75901 tctatggcag tgaacatcat cgtcaatgca aaagcttccc gtccatctgt ctgtaacgcg
    75961 gcagaaacat tgctgatcca ttctgagatc gcaccttttt tcttgccagc tattgaaaaa
    76021 gaactggtag aacacggggt ctctttacgt gcggatgctc gtgcgttaga atatctagag
    76081 acggctgctt tagcagaaga cacagattgg gatactgaat atctagatta tatccttgct
    76141 gtcaaagtgg tcgattcttt ggatgaagca attgcacata tcaatcggca taatactaaa
    76201 cattcagaaa cgatcgtgac agatagttat gcggctagtc aacgtttctt aaatgaagtg
    76261 gacgcggcgg ctgtctatgt caatgcctcc actcgtttta cagacggatc ggtatttggt
    76321 tttggtgcag agattggtat ctctactcaa aagttgcatg cccgtggtcc aatggggtta
    76381 aatgaattaa cttccacaaa atatatcatt tatggcgatg gacaaatccg cgaataatgt
    76441 ttcgtgtgaa acattattcc cgccttttgc cttttttctg taaaggttct atccaactag
    76501 aaaggtgtca atatgtttga aattttaatg atttttttta tttaccttat ttctctgaat
    76561 atcgctgctt ttctgggagt cggtatttta tcccttttct ttcaattcaa aaaacgaagc
    76621 atagggagtc aacgggaaaa atggtcgcag tattttgaca aaatcgggca aaaagggctg
    76681 gttacacgct tgcacattag ttacatggtt gcattatgct tattagcgac aatcaattac
    76741 tattcttttt tcgatcattc aatcgcttat acgattacgc tactgattgc tgggattttt
    76801 cacttatctt ataaatatca gctgaataaa aaccacttga atcggacttt ccgctaaaaa
    76861 atatccgtac gataagtaga gtgccttgaa gatcggcaaa aaactgccgg actttttaga
    76921 ggctgtgaca aagattttgt cacagcctct ttttccatat aaacggcgtt cgcctaccag
    76981 ctgcctggta aatctgtttc ctcttcgtta agaagcgaaa atccgtcaaa tgtttcgcca
    77041 tcataataac gaagcagctc atccatggac aagttcatcg ttttttcttt ttcttcttcc
    77101 gctgattcag ccagtagctg ttcccgatac acctgataca taccagctat tttttgctgc
    77161 atcgcttttc tagtttcacc ttccgcattg attattggca attctttgat atagccacga
    77221 taaatcaacc gatcatctga aaattcaatg ggtaattcaa cgagtgtcaa cccgacttcc
    77281 tgaaaatatt cttccagcat ctattatccc cccattcttt ttcttaaatg aattttagct
    77341 tacctactga aaattttcca gtttcattat tttgagaaaa aaagggaatg tgacaaaaat
    77401 cgtgtcacat cccctttttc cgaataaatg gtgttcttct gccaactcct caatcataag
    77461 tcacaatatt caacaaacat gagaaactgt tttttgaaat tgttccttgt gattcagagt
    77521 taaacgacag tctcacaacc tcttggtaaa cggcgttcaa tcagctgacc ctcggtatta
    77581 gctcaaaaaa cggtaaaata tgagaagcta tttttccgtt ttgtttctct aatacttagg
    77641 ataaaacgct gattttacaa cctctgttaa acggtgttca atcagctgtc cttcggtatt
    77701 agctcaaaaa acggcaaaat atgaggaact atttttccgt ttgtttctct aatactcagg
    77761 acaaaacgct gattttacaa cctcctgata aacggtgttc aaaagcttgc atctgcggta
    77821 ataagcccaa ccaaacgaaa aatatgagaa gctatttttg tttggctgtt cttatgactt
    77881 gatgcaggac agctttttca caacctctga tttcttattc ttcttcattt gtagcaaaat
    77941 aattacggtg ataaatgata caacatacac tgataagaac aatggcacct gcaaaataaa
    78001 acgcatagct ttcaccaata tgttcaccaa tcacacctgc aataaatggt gctaaagctc
    78061 caccgaaaaa gcggacaaaa ctatagctgg acgaagcaac gtttcgttgc agacctggta
    78121 tttccatagc aatcgtcgtc aacagtgtat tgataattcc ttggaaaaat cctgctaaca
    78181 caatgctgat cggtacaagg actggcatag aagttccagc tcctaataac agcaaacaaa
    78241 taatgaataa gacaaatgct gctaaaattg tccgataagt cgtaaacttc cgctcaagag
    78301 ccggtgcaac gaaaatcgaa gcaatagcca gaagcacacc ccagccaaaa aatacaaaac
    78361 cgacttctaa ttcagaatag ccaatcaata aaaatggcgc atacgcaagt aaagtaaaga
    78421 atccgaaatt atataacaat gcgattagtc caactgaacg aagtttatga ttgcttaacg
    78481 ctttgacacc ttcccaaagg cctacttttc tctttggttt ctcagtttca ggtaaaagta
    78541 ccgctagggc tataaaaccg caaaacatca aaaatgctac cccaaaaaat ggataacgcc
    78601 atgaaccact gcccaagacc ccaccgacta gagggccaac agccattccg cagccaagtg
    78661 ctgcttcata catcatgatt gctttttctg tgttaccaac taaaatactg acgatcgttg
    78721 ctaaagcagt agagacaaat aaagcattcc cgacacccca gccggcacgt aacccaatca
    78781 gcattccgat attcccagat aatccgccaa gaccagcgaa tacaacgatg ataaacaatc
    78841 ctgtcatcaa tgtttttttc aaaccgatcc gactagataa gaaacctgta aatagcatca
    78901 ccacaccagt gactaacatg taactagtaa ataacagggt cgtttcagct ggcgtagcgt
    78961 ttaactgtgc agcaatcgtt tttaagattg ggtctactag acccactccc ataaaagcga
    79021 tcatacaggt agctgctaca actagcgctg aacttttccc ctttgtttct tcatttgttt
    79081 gttcttgtat atctatttga ttctccaata tttccatccc tttctctcta ttagcatcat
    79141 acatgattta ttttacatgt caatatgcac atgtaaaacg tggaaacttt actgtgatat
    79201 aataaagaaa ataagacgag aggtaggatt tttatgaata ctttagccta tatattatta
    79261 tgcgtgcttt tatccaaacc acgttctggg tatgaattga agcagctgat cacaattttt
    79321 tgggaagccc atcacagtca gatctataca acgcttgcca agttagacca gcagggttat
    79381 gtgaccgttt tggacaaaga cgagcactct caaaaaaaga tctaccactt gactgatgaa
    79441 ggacgtgctc ttgtagagga atggatcaaa gaggaaactc ccgctcctac gcaaaaagat
    79501 gaatttctag caaaaatcta tgctttttcg acgctcgata aaacaacagc tactggactg
    79561 ctattcacta gagaacaaca gctgaacaaa atcatgcaaa aaaatcaaaa aaaattgaat
    79621 gacctctcgc tagacaagaa acaagaattt ggacgttatg ttgtgatcca gcgcagaatt
    79681 atgctttgtc agcaggaact ccaatggtgt cagcaagtaa gagaacaaat gcagcagttt
    79741 tttgagtaag ggataaacag aacctttcta gaaatatcta ttgaagagca aattatcttc
    79801 aataaaagag caatacagtt ggaaaagaaa aagcgatccg aacgacaggc caaaacctat
    79861 cgttcggatc actatttttc tagaactgca ttcaagagac tatgacaaaa agcatgccaa
    79921 ggcctttttt caaataacag tgttccatca ttcattactt tgaattgctt ttagcacact
    79981 tcttgaaagc gggccaacga tgatcaactg caacggtaaa gcggcaatca cattcatttt
    80041 ccaagcattc atataagcag agaataattg atcaggtatt ccttgttcca tgatcacacc
    80101 gaataaagac atacatgtca ccattcctaa aaccatcaag catgaaatag ttaagatcat
    80161 ttggaccttg ctttctggat ttactggtag tttaaaggca atttttttcg ccagcacacc
    80221 gatgatgaag acatccaaaa tgaaagccac cacgaatcca ggcactagac caatcaacaa
    80281 acttgataaa tgaagatctt gatgcagcca taaattatac gcgctcatcc ccaagaccat
    80341 caaaaaacac atcattgttg taaaaattat tccttctttt ttatttgtag gcaatctgta
    80401 ccactccttt aaatttgtca cgaaaatcat cgtagcacat ttaaaaattt ctcgtaagta
    80461 ctttttttat tttctgccct tttatttcat aaacttcatc agccgtacgc tcgacaaagt
    80521 aagaatcatg agaagtaaac aaaatcgttc ccggatatat ttgcattagc ttctctaaag
    80581 cttcgatcgt tgccatatca ataaaattag tcggttcatc taacagcaac acattacttg
    80641 gcttagtaaa aagcaaagca atcgtcagac gggtcgcttc tcccccactt aatgtacata
    80701 acggtttcgt caaagtttcc tgagcaaacc ctaagtgatt cagcaaacta cggacaagcg
    80761 attctgaaaa ctctgtttgt ctcatgacaa aacgaatgat ggattcttca gatgtcattt
    80821 gataaccctt ttgctgatat acttgaaagc ttactttcgg agagagaagg attccttctc
    80881 cttgtttgcg gatatgttct aataaggttg tcttacctga accattttca ccgacaatcg
    80941 cgattttttt acctaaagaa aactgaaaat caccatttac cagtaatgtt ctcccacttc
    81001 tttccaattg gacattttgt cccatgatgg gatagcggct gtggagttca agagattttg
    81061 gtactggaaa acggatttgt ttcatctgct gcggcttggt tgtttctcct attttttgga
    81121 gtcttctctc taatgttttc gcattctttt ggatggcttt ttgtacactg tctttttgtt
    81181 tagaggaaga caaccgatcc agtctgattt gttgcttttt ctttttactg gacacttttt
    81241 ccaacttttc cgcttgtttt ttcttttctt ggatcgattt ttccaatcgt tttttctctt
    81301 tcatgatcga ctctgcttct cgtagctgag tctttttctc caattccttt tgagtgagat
    81361 aggcactata attccccgaa aactctcgga tttctccgtc ttttacttcc cagattttcg
    81421 atgctagctc atctagaaaa tagcgatcat gactaacaaa aaccagcgta ccataataat
    81481 aacgaagctc ttcaatcagt cgatcaatac tttttctatc tagatgggtt gttggctcgt
    81541 ctagaagcat cccttgttca taagaagaaa gaagacgtat caactcgatc tttcgttctt
    81601 cccctccgct ccatttccgc tctgaagttt cttccagtct taactggaaa tgactggcta
    81661 attccaaatt taggtccttt gcttcagcga gataggttaa ttgaggcagg tagttgaagg
    81721 tgatctctgt ttggattttc ccatgatcgg gaaaaagttc accggctatt agtttgagca
    81781 aagtcgattt accgacacca ttttctccta tgatccctat acgatcttgc tgatagacac
    81841 gaagagaatc aatagatagt tctagctggt tgccaaagct gacttgtaga tttgttatat
    81901 ttactgctaa attttccata tgttttacac tcctatttca tgtaaaacaa caattatcga
    81961 tactaaaaaa gagcagaaaa atctgtttgc aaaaaaactg catcacatct tttcctactc
    82021 tgaacgaaat aactatgact aaatcaccaa atctgtcata gctttcacct attctactgt
    82081 cgttcgaaaa aatggacata ctccatccat gaaattgttg tttatacatg tcttttgaat
    82141 ttatttagtt gttattcaaa agttcgaaac gtaatttcat cgatgcagtc atttttccga
    82201 cctccttttt tattaggtta ccacacacga ttcaaaaaaa gcaatagcta ctgaatagta
    82261 actgaaaacc ttttattcga acatagtgat cttttctggt gctaaacgaa cagactcgta
    82321 accttcttct accgcttttc ctattgataa aataataact ggaacataac ggtctttatc
    82381 caaaccaaat gcctctgcca actgatctgc ttcgaatcca ccaattggat ttgtttcata
    82441 gccatgatca cgcgcaacta acatgaattg catagccgct aagctagaat cgactttgac
    82501 tacatcgttc atttcttctc ttgaaaaact cttgtaataa ggaatgatcg cagctaattg
    82561 ttgatctctg acttcttttg gcatcttccc tgattcgtaa gcttggttgt agatttcttc
    82621 gccatattcg taacattgca tatcgccaaa aatcatgacc attgcagaag aagtatcatt
    82681 ttgtctcgta ttgaaacgga tcaaaggacg caagatttct tttgcttcct cgctttcagc
    82741 gaccacaaag cgccatggtt tcatattgac agaagaaggt gcagtcgtcg cttctttgat
    82801 catttccagc atttcttcgt gtgggatttt gtatgtttca tcatatacgc gaacggatct
    82861 tctaccagtc ataattgttg aaaaatcatt tttttgttcc attattatta acctctttcg
    82921 tttctgttgt tatattgcaa agttgggtat tcaatttatc taaaagtgtt agaaattgtt
    82981 tcatttctac atcgctgaaa gccggggata gcacggaacc tgtatcttta tggtccattt
    83041 cacaatgctt gattttcttc tgggcttttt ctgttagcgc tacatacact tcccggttgt
    83101 tctgaggatt tctctgacgc gaaacatagc catttgcttc caataccttc agatgacgag
    83161 taactgctcc ttgatcaatc tgcaactttt cttgcaaact gctttgtagc aatggatttt
    83221 cttctttcag tctcatcatg atctcgtatc tagtaagact tataccgata ttttcttcaa
    83281 agatctggac gattttttga tcggctaatt tgatttgata taaaaggtga ctaatctctt
    83341 ctaaagacat aatttcctcc tttctaataa ttgactcgtc aacgattgac ttgtcaataa
    83401 tagaataaaa aaagaaaaaa gtcaaagaat cagctgtgta ataaaaaaaa cgctctcaat
    83461 agaaaagtat agagaaaaga aattttttgt agaatgaacg gaaaaaatga taaagaaagc
    83521 acaacgctaa aaccaagatt attgattctt atcaaactat agaagatagc tcttctgcag
    83581 tagataattt tacaccgcca aaaatttccg aaatcgcctt ttgcaagaat cccgtcgaat
    83641 attagaaatt ggatcagtat gcttaaacag taataaaaaa gttatgacaa gatgttgtca
    83701 caaccttttt tgagtaaacg gtgttcaaaa acttgcatct gcggtaataa gttcaaccaa
    83761 acaaaaaaca tgaaaatctg tttttgtttg gctgttctta ctacttgatg cagggcagct
    83821 ttttcactac ctctttttaa taaccataaa atcctattcc ttcatatctc cagcccatcg
    83881 gtgttagcca atctctttcc ttagcactca aggtatagtg atgggtacca gttttttcat
    83941 ttggattaaa tagtcgataa attggcttgg aaccaccaga ataaaaactt agaccttcat
    84001 aacgccaacc gatttttgtt aaagagttga tctcagattg tgccattgtg taatgatggt
    84061 ctccactgta aggattgtat aaacggtaga caggttgtcc gctgtttggt gcttgccaag
    84121 caatcccttc atattcccag cctacagttg gcagataatt tttttctccg gcattcaatg
    84181 tatataaatg ttctcctgta tgacggttat acagacgata catcggagaa gttgaagttg
    84241 gtgctgtatc atactgtgtc agattatagg tttcgattac attgttcaat gtagaaccat
    84301 aattaggcgc agtggcataa cgacctgtta gccaagccgt agcatctttg taagagttcg
    84361 tattgctttt ccatgcaccg gaatagtagt aaacgcctgg ctgaaaagaa gtcgtcttca
    84421 ataccgttac gttatcttgc aatgattctt tgtacgaagg atattttcta aaagcggcat
    84481 tcaccgtaat ccattgccca ttcacatatt ccgaagtagg catcgtaaca gattggccat
    84541 tatagcttcc tttaatccca aatagattgt aattaggggc agaagccaaa gtactgttcc
    84601 cccagccact ttcaacgatg gcttgagcaa tcatgactga tgcatataag tcattggcac
    84661 ttgccaaact ttgtgcagtt gaggcaatac tatcaatgaa cgcttgttga gaattagcag
    84721 atgagcgagc ataaaaagca tagccagtat agttttcgaa ttcagacaaa tctgcttgat
    84781 gggtatgtgt caatgtttgc ccatctgtca attggttcgt gatttcttct gcattctctg
    84841 gattgttctg agcttctgct gatgtactgt cttcggtttg tgtttgttct gttgtttcag
    84901 ttgttggttc ttcggttgaa attgtatttt ctgagacagt agctgactgc aaagtacttt
    84961 ctgtatcgtt ttcaattcct gtttctgaag aactcgatgt ctgagttgcg acagtttctg
    85021 tcgattcttc agctagcact gttgtgttgg caactgctag atttcctaaa agaataacgc
    85081 taaataataa attctttgct ttcatctttt ttctcctttg aattatgaaa cttttcctaa
    85141 ataacagtgt aactaaaaaa gtaaaagcaa gtcaatgtcc atatttaaat aacatttgtt
    85201 tctttttaat aaatttgctt tttctgcata aaaagacgta aatgaagaat attcttctcc
    85261 attcacgcct taaattgatg gtcgtttgaa taactattta acaagtaatt ctctctggat
    85321 attatccgtt atggattata cttcctgtgt cgtcggacgg ataatcatgt tgctgacaga
    85381 catccggtct ggcgtttcta tcgcaaatgc tacagcagaa gctatatctt cagatgttaa
    85441 tccccattct ttttgcgctt catgaagttc aagagcagcc tttttgtcgc tgatggtttg
    85501 atataattca gtttgaacag ctcctggaga gatgatcgta gatttgatgt tattttgccg
    85561 ttgctcttga cgtaatcctt ccatgattgc acggacagca aattttgttc cgcaataaac
    85621 ggcggaatca ggataaacaa catgtcccgc cacagaatca gttgaaatga tatgcccaga
    85681 tttttgtttt tccatgattg gaagtacggc ggaaattcca tttaacacac ccatgatgtt
    85741 gatatcaagc atattttgcc attcatcacg gtgaccttca actaatggag cggttggcat
    85801 gattcctgca ttattgtaca atacatcgat tcgaccgaac ttttccatcg ctaaatcgat
    85861 aactgcttgg acttgtgcaa aatctcttac atctgctgtt tgaatatata gctcagcttc
    85921 tggtaaagat tcttttattg cttttaggcg atcttctcgg cgtgcagcta taactagttt
    85981 agcccctttt tctgctaata gcttcgttgt tgcttcaccg attccgcttg aagcgcccat
    86041 gatgacaatc actttttctg ataaatcatt cattctattc tcctcctgtt ttgaaaaatc
    86101 tcttgcttat actcactatc tcttatttca tcttactgtt caaataatcc gttcgacagg
    86161 tttgacgatt ttggcaggga ttcctgcaac gatggtattg tctgggacat ctttcgtaac
    86221 agttgcattc gctgcaacaa tggcattctc gccaatcgtt acgcctggca gaatagttgc
    86281 tcctgctccg atccaagcat ttttcttgat gtggattggc tttactgaca agcctcttcg
    86341 ttcttttgga tcggttagat ggttcaccgt gatgaggttg acacgaggac caatcaatac
    86401 tgaatcttct aaacagatgc cacctaagtc aacgaacatc acttgacgat tgataaagac
    86461 atttttccct atactaatat gtttgccgaa atctgtataa aaaggcagca gaacagtcac
    86521 cgtatcatct actttgtcac taatgatatt ttctagccgt ttgcggatat ctgctggttc
    86581 atggtaccca gtattcagcg ctgctaaagg ctcttcgttt tccgcttgga tctgatggat
    86641 cacttcaaag agcggatccg ttactcgaat ctctttattg acgatttgtt tttcgatgag
    86701 gcttgtcatt ttgctccctc cttttatcct tactttataa cggacggctt atgatgtcta
    86761 atacttataa aacatactta actattcctt ttaactatac ttagtggtat gcttttttaa
    86821 aaacaggagg gaaaaaatgg atattcgtat actgacgtat tttttagcag tagctagaga
    86881 aaaaaatatc agccgagcag caaaatctct gcatatcacg caacctactc tctcaaaaca
    86941 actgaaagat ttagaagaag aacttggtgt gacacttttc actcgaggct cccgagagat
    87001 acagttgacg gattctggtc gatatcttta ttcaaaagga aaagaaatct tgtcgttggt
    87061 agaaaaaacg gcgaacaatt taacaaatga cgcaatcatc tctggagaaa tctacattgg
    87121 cggaggcgaa actaaagcaa tctctttcat ttctgatagc cttcattcgt tgatcaaggc
    87181 gcatcctgat atccagtttc atttatatag cgggaatgca gatgatatca tagacaaact
    87241 ggatagcgga ttacttgatt ttggactcgt aatcgaaccg acaaacaaac aaaaatacca
    87301 gtcatttcga ctgccagccc aagatcgttg gggacttttg atacatcgga atcatccttt
    87361 agcaaagcaa acagtcatcc atccgcagga actgaaaact gttcctttga tcatttcccg
    87421 gcaaacgtca gtggacagtc aactagctga atggctaggt ttcagcatag atcagttatc
    87481 gatcgtcgga acatataact tattgtacaa tgcttctttg atggtcgata acgggacttt
    87541 tggtgcatta gctctagatg ggatcatcaa tacttatggg acggaaaaag tattcatccc
    87601 actcgatccg ccattacaag cttcactgaa tctcatttgg aaaaaagacc agcctctttc
    87661 tcctgctgct cgtaaatttt tagatgtcct aacggagaaa tacagttaag tagagttttt
    87721 ttccttcgct ttcagctttt taacaacgaa taagttaagc aaaagatcca atgattaaat
    87781 aacataagtt tcttaatttg ttccttcctt ttatttctga taattccagt aaattactat
    87841 aattataaaa aaagaattga caaaacataa ctgtctatat aaaattgatt acgttaacaa
    87901 taattcgttt catgtgacta gatcatacta ggcatgaaaa atctctgagg aacatggttt
    87961 ccctaggagg tttttcgtgt ctatttttgt ttggccgcaa tcaactggtc tagcaaacgt
    88021 gaaaaccaaa tcttcaaaaa gggtgcgcgc atgaaaatca aaaagatctt taatcaaaat
    88081 gcagtattgg tagatgacgg tggacaggaa aaagtagcta ttggaaaagg gattggattt
    88141 gacagaaaaa gaaatgattt gatttttgat cgtgatgtcg aacggatatt tgtcatggaa
    88201 ccagaaggtc aaatcaagtt gcaaaattta cttaatcaga ttgatgaacg ctttttattt
    88261 gcagcagaaa cgatcattga tcatgcggaa actgttttga tggaaaagtt gaatgaacat
    88321 gtattgatcg ctttgaccga ccacattgct ttttctgcgg agaacattaa taacggtatc
    88381 gtcatccgca acaaactttt aagagaaatc gaagtgcttt acagtgatga attcagtatt
    88441 gctcaatggg cagtagagta tctgacaaaa gagcttggga ttccatatac ttatgacgaa
    88501 gcaggatata tcgcaatcca tattcacagc ggacgaagcg gtcggaacaa taaccatcgc
    88561 agtatccgtg aagtgacgat tgtatctgac atcatccatt tagtggaatc agaattggaa
    88621 acagatatcc attcagaacc attttcactg aattattcaa gactggtgaa tcatttacga
    88681 ctgcttctac aacgaaccca tgcgcaacaa tatgctgttt tagacacgga aatcgtagaa
    88741 atggtcaaac gaaaataccc agaaagctat aagatttcta aaaaaatccg tgtgttgctg
    88801 accaaagaat accagctcgc gatcacgaaa gaagaactgg gttacttggc catccatatc
    88861 gagcgtttaa gaagcgcaat cgtacaaaca aatgttaaca atcatgagga ggaaaaaaat
    88921 tgaaagcata tctacaacga atgggacgtt cccttcaact tccagttgcg gtcttacctg
    88981 ctgctgcttt actagtaggg atcggaaact ggtgggcatc ttatagtaac gacattgtcg
    89041 ctcatttttt acaagctggc ggtaacgcag ttttaggtca attacctttg ctgtttgccg
    89101 ttgggttagc actagggatg tcagtggaca aatcaggtgc tgctgccttg gcaggtttgg
    89161 tcgcatttga agttccagta aatgttttaa aaactgattc agtagctact ttattgaata
    89221 tcaaaccaga atcagttgat ccatcttttg ctcagatcag taacgtattt attggtatta
    89281 ttgccggatt gattgcggca gctctttata atcgtttcca cgaagcaaaa ttaccgatgg
    89341 ctttatcttt ctttagcggc aagcgtctag tgccaatctt ggctgccttt gtcatgttgc
    89401 tgatcagtgc agtgctactg ctcgtatggc ctccggttta ctctgcttta gtttcttttg
    89461 ctaaattcat tttgagttta ggctggggtg gtgcaggtct ttatggcttc ttcaaccgtt
    89521 tactgatccc tacaggattg catcaagcaa tgaactccgt gttctggttt gacgtagcag
    89581 gaatcaatga tattggtaaa tttttggctt ctgaaggaac aaaaggcgta acaggaatgt
    89641 atcaagctgg atttttccca atcatgatgt tcgggcttcc agcaggagca tatgctattt
    89701 acagaaatgc acgtccagaa aacaaagcaa aaacagcttc cttgatgtta gcagcagctt
    89761 ttgcttcatt ctttactggt gtaacagaac cacttgaatt ctcatttatg ttcgttgctt
    89821 ggccattata tgtcttgcat gcaattttca ctgggatttc tttagcagtg agtgcattct
    89881 tccattggac agcaggattt gcctttagtg ccggatttgt cgattacttc ctatctttga
    89941 aaaatccgat tgcgaatcag ccattgatgt tgatcgtcca aggattagta acagcagtga
    90001 tttactactt tggctttaac tttgctatca aaaaattcca tctgatgact cctggccgcg
    90061 aggaagcaga tctttcagat gacgatactg caacgactaa ttcagacaat aaatatgcgg
    90121 cacaagcaag caaaatctac gctgcattag gcggagccga caatgtaact tcgatcgata
    90181 actgtactac acgccttcgt ttgcaagtca aagatacagg cctgatcgat caaaataaaa
    90241 tcaaagccac tggcgtacct ggtatgaaga tcatcgacgg aaaaaatgcg caagtcatcg
    90301 taggtacaga agtacaattc gttgcagatg agatggcaaa actacatggt ggtgctgcaa
    90361 cacgacctgc acaaacaaac accgtggtta aaacagaaac atttgccggt ggaacgatcg
    90421 aacaagatat ttacgctatc gcaaatggga aactgattcc aatcactgaa gtttcagatg
    90481 atgtattcgc ggaaaaaatg atgggtgacg gctatgctgt attaccagaa aatggagaaa
    90541 tcttctctcc aatcgctggt acgatcacaa acattttccc aacgaaacat gctgtcggaa
    90601 tccaaacaga tgctggtatc gaagtcttgc ttcatatggg catcaacact gttgacttaa
    90661 aaggcgaacc attcacttta tatgtaaaag aaggtcaaaa agtcgcaaga ggtcaattga
    90721 ttgctttagt tgatcttgcc gctattcaat ctgcaggcaa aaacacggat atggtcgttg
    90781 tattcacaaa tggcgacaaa gtccaaagct tagaaatcga acccgcacgt gatgtaaaag
    90841 caaatgataa aatcggctct gtttccaaca aagcctgagc catcgtcttc cccagacttt
    90901 tttatcgata aacaaacagg agctgagaca aaaatcttgt ctcagctcct ttttccgaat
    90961 aaaaacggcg ttctcctgcc aactccgcgg taataagtcc agccaaacgt aacatatgaa
    91021 gagctatttt ttatttgact cttcttatta cttgatgcag aacagctttt ttacaacctc
    91081 tgataaacgg tgttcaaaaa ccagtttatc ggtatgaagt caaatttatg caaaaatgtg
    91141 gaaagccatt ttcacaaaat ttttcttcat actcaaaact aatcggcttt ttcacaacct
    91201 ctttatacat tattcctgat ccaatatttc ttttaatgct gcttcaagag aagttaatgg
    91261 ttttcccaat actttttcta aatcatcaga ggaaatagct aactgatcct ttttaatatc
    91321 atgttggatc gctaaaaaca tgtcagctgc ttcttgaggg aatccggctt cttttagatt
    91381 ttcgacaaac gctgcatcac ttgcttcaat aatttctaac tttttacctg tcgcacgctc
    91441 taatgccttg gctaattctt catagtcagt tagattgccg gataattcta agatttctgg
    91501 agagtcactt tctactagta cttttgctgc agcttctgca tattcacgtt tcaatgccca
    91561 acctgttttt ccatttcctg cagcataaac gaattgacca gtttttaaag cctgcccaat
    91621 gataggtaat tcattctcta cataccaatt attccgtaaa aatgtatggg aaatacctga
    91681 atccttaatc attttttcag tgaattggtg atctggcgct aatacactga tcgagtgatc
    91741 ggcatctgca aaacttgtat aagcgatata agatacccca gctgcttgtg ctgccttcac
    91801 tacattctta tgttcggctt gacgatttcc tggaacgcca gagacaaaaa gcaatcgatc
    91861 tattcctttc aacgcttctt tcattgagtc taaatcatca taatcaccaa tacgtatatt
    91921 aaatccagct tctttcagtg cttctccttt ttcttcacta cgtactagta catagatttc
    91981 attttgtgga accatctttt ttaagaattc cagcgcataa ccaccaaaac ctccagttgc
    92041 tcctgttact aaataatgca tatttgccac tccctattct ttttatttgt taagatttac
    92101 agctgtacat ttataaatta cacctttatc ataaagagtg tggtaagata agtcaagcaa
    92161 aaaaaatgaa aggatgacaa ctgatgaagt attctctgca atttagtgat gcaatccatg
    92221 tacttgccta tattgaaatg tttcaagata cccgatcact ttctagtgag atgattgcca
    92281 gtagtatcga aacaaatgca gcaaatgtac gtaaaatcat gagtcagctc aaaaaatccg
    92341 gtttgatctt tacaaaaacc ggaaaaccgc agccttccct tgccaaaagt ccagatcaga
    92401 tttctttact agatgtctat cgcagcatcg aaggtaatac acagcttatc caagtcgatc
    92461 caaaaacaaa tccaaattgc gtcgttggtg cgaatatcca agaagcttta gaagaaagct
    92521 acgctcggct gcagaaaaag gcagaagaag aaatggctaa gatcacactt gatagtctga
    92581 tacataaaat agccgttttg gaaaaagaaa aaagaccaga aaacacaggc ctcgtagaga
    92641 gatttttata attctctcta ctgtgcctgc atttttctga tcggaatcgt ctacataaat
    92701 tcttttattc tccgggggac aaaagccttg tcatgcccct ttttcctctc taatgctcag
    92761 gtcaaagcgc tgaagtcatg acgtcttgat aaacggtgtt caagtagctg accctcggca
    92821 ttagttctga aaaatgcaaa atatggaaag ctatttccca tttttcctct ctaatgctca
    92881 ggtcaaagcg ctactttcac gacctctata ttatcatggt ttattgacta ccggtatcca
    92941 gatttctccc atatatttcc cgttggtaac tcccatttcg actacagcat ttggaccccc
    93001 aacataggcg taatcttcta cttctcttaa aacatgccca aaggccgtat tcgtcaaatc
    93061 atttcttaat tcttcaggcg attctgctaa agcgattaca acaagatacg ttccttttgg
    93121 gaatgggatg attcgggtag tgtttggaac atcctgactc gtttgaacac cgacatagta
    93181 catcattttc ccgttatagg gttcgttgac tgtaaagaaa taatgatttt cagcagcttg
    93241 tttcaatgca tctattgttc cattaccgat aactttttgc tcaaatgctt gtttctctgc
    93301 agccaaaccg acaaaatccg tattgctact cttcaattcc acaccaatac ccgtcaccgt
    93361 aaaatctggt ttttcttcga tcctatactt tgccatttct cccacccttt ctattatatt
    93421 aagttcatct tacataaaat taaagggaaa tgacacgatt acgctctttt ttctagggat
    93481 atttttattt tttaactatt tttttgcttt cactgcaatc caaatctcac tgtaaacatt
    93541 actgaaatcc tctccccatt ttgtaaaaga gatctcggga gcttcgacta actcataatc
    93601 tgaagaagga agccattctg catagatttt cccccaagta tcttgtaaag tttggggaaa
    93661 tggcccttta ttaggaaaaa tggcccaagt gtgttcttct atagcaagca tttctaaatc
    93721 agcgtacgga ttttcttttg tcgtagcaaa gccaatcatg tgcatcaaac tgcccttttc
    93781 ttccaagcgg gctccatcaa atccataaga aacgttgatt acttgatttg gatataaatc
    93841 tcctaactta tgcatctctt ccctttgagt ctccgtgatc gtctgcgcta acttttgtat
    93901 ttcttgattg actccttcaa atttgacagg aacttttttc gccacacctg ccacataaaa
    93961 ctgttctttc ttttcgatac gaaattccat cgattttcct cctctgacat caataaaaaa
    94021 tgtcaagcgt ggaaaagatt tttgtatgcc gtatctgctg atttctgaag gcagatatcc
    94081 tgaccaatca cgaaaagctc ttgaaaaacc ttcgactgtt tcatatccat atctaaacgc
    94141 cgtttctgtc actcttgatc catctaggag atcgcgatta gccaaagcca atctacggtt
    94201 tttgatatag tccattagcg acatccctgc aataaacgta aagatgcgtt ttaattgata
    94261 ttcagagatt cctgtatttt cggctattat tttataggaa agtccttctg tcaaatgttc
    94321 ttcgatgtaa tcgatcaatt ggttcagatc tttaagcata tttatcttcc tccttgcttg
    94381 cctttttatc atattatcaa agaaagtcaa ttacttgatg aatcaggaac caatttagtc
    94441 agatgtagaa aatgttgtat ggatctaaag aaaattctca agcagcgttt cgtaacggat
    94501 aattggtatt atctgcctat ctatgtttta cctttagaaa aataaatttt ggggaagaca
    94561 cattctaagt aaacaaagcg gtaaaaatat cttttattcc cttagttaat ccgcttacta
    94621 cctactgtac aaagcaaatt gttgttcaaa ctgctgatca gaacgctgct tggatttttc
    94681 tttgcgatac atcatacctc ttttatcaat tggaacaatt atttatttct aacaaaatca
    94741 cttcattttt gtcagataaa taaaaaacaa aaaaagttcc atctttaaaa cacgctattc
    94801 ttttactttt tctcacattc tctaagaaaa gaaaaggaga atgaattttt gacaattcga
    94861 gcaaaagtga ttatcaaata tgtaaaatca gctacttttt tcttaaacgt ttctttatac
    94921 taaatataaa taagtgtttc atgaaaggag aactagatga ataattggct tgagtatttt
    94981 cctgaaaacg ttttggaacg cggttacagc tatcatctgc acggttttgt ccgtcatttg
    95041 aactatacaa gcaagtactt gtccgcaaca gtttctggca cggaagatta taaggtagtg
    95101 atcacttggg atgaaaagac caacatgact tgtgattgtc tatatgccat agaaggaaaa
    95161 aaatgcaaac acatggctgc tgtcttattc gcttacgaag aacgtccaat aaaaaaatcc
    95221 aactactcac tttccgaact ctcgtccctt gtttcctccg ctagttcctc tcttgtacgg
    95281 gagcttttaa cagagattct tatagaacat ccgcaattta tcgaacgctt caaagttaag
    95341 atgccatttc atgcaataaa ttattcagat aaattaacaa ctatcatcca taaatacgat
    95401 catattatca agaaaaacaa aaacaggaaa acagcgaagt tcatcatgga gatgcgaaag
    95461 ttcatccaag aagcagttga atcgctcatt cagcaaaatg cctatcttcc cgcattcgaa
    95521 ttgatcaatg aagtgattgc tactctcgaa acattctatt gggagcctga ggatgaacga
    95581 acccttcttc tgatagagga ctgttattat ttatggaaag aattattagc agaagcacct
    95641 catgcagaaa aaaggcaaat gttctcttgg ttcgtctgcc aagtcgatca tactgacgcc
    95701 tcttattcaa aacgctactc cataaaaatc ctgaaagaag actttcggga aaaagaattt
    95761 tctaaccaaa agaaaaaaat agataaaaaa actaaagaaa cggtaaagaa agacgatttc
    95821 aatgaaaaat agcaagtaaa cgataacaac catcctaaat ccacaagaaa tacagcagac
    95881 cttgctttaa aaacacgaat catgcaaagg atgaagtaaa gaagacttaa cgcgtaccca
    95941 atattagtca tttgactatt aggtacgcgt tttgttttat aagtcatgac aaatttcctt
    96001 cgttgctggg tagattttcc ggcattgttg atagatttta tgatactttt ctacattttg
    96061 taagagaggt tccactgcat ctgtatattg gataaaattc tgacaacaac tttcaggtgt
    96121 gtcgaaccac tctaatcttt aaagataaat attaaaataa cgattaataa tattaacagt
    96181 ctttattttt caccaccaaa aacctatctt tgcatatact aaatagacgt atatacacag
    96241 ataggtttgt cttgtgaaaa ataatgatta tccttaccaa aaaatgtttg tttttctaca
    96301 tgttcgtact tatcaaaaaa tatgatcctt attgaaatta ctggctattt atattccaac
    96361 gacttcttgt gttaattttt gttatctcat agtaaattat gtttcatttt cacttaattt
    96421 agttgtcacg tgttcgtcaa ttcgtaaaaa cggtaaatat ataaacacac ttgcggctat
    96481 aattaatatt tgtaaaacag ctgctcgcca gtctccggct gttgctaaaa atcccgatat
    96541 aactggtggc gtagtccaag gaatttgcac tactacatga ttaattaatc ccacagcagt
    96601 tgcaaaatat gctactgtca aagaaaaaat cggtgcaagc acaaagggaa taatcagact
    96661 gatattaaat acaataggca atccaaaaat aataggttcg cttatattga atatagcggg
    96721 agttaccgat aatttagcaa agtccttata atcttttcta cgactgaaga taaatattgc
    96781 aatcaataaa gcaatcgtat ttcccgatcc acccattacc gcaaaggtat ctttaaaggc
    96841 catattgata atatgtggaa tttgctcttt gtttgcataa gctgccatat tttcttgcat
    96901 attctgaatc aaaaacggat ctaacaatga acctgatatt actgcttgat ggataccaaa
    96961 tccaaaaaat agattagcaa tagatgtaat taacaaaaat cctggtaaac cagttgtaat
    97021 tttacttaat ggctctgtaa ctatcgtggt aattagctta tttatatcca tattaaacaa
    97081 ttgaatgatt ataaatgaca ataaagcaaa cgaggtaatc gtaataatga ttgggattaa
    97141 tacattaaaa gactttaaaa cagcgggagg aatatttccg gatagctgaa tctgtagttt
    97201 cttattatta gaaagtttaa taaataattc tgtagccgct aatccaacaa atatacctac
    97261 aaacattcct gaagctcctg tataggatat aggtatcaca cccgtcactt caacagcttt
    97321 atccgcattt tcaggagtaa acatcatctg cataggtgtt aatacaacaa atgtcgaaat
    97381 agcaactaat accgctgcaa tatgatttgt ataatttctg cttgcacaca tatgataaga
    97441 tactgctgct acaactaata atgtagttat gcttaatgta ccattggcaa ttgaagtacc
    97501 aatttgttgt aacgtggtca atgtactagt atcgacaatt tcccccatga atcctgttgg
    97561 ttctaagatc actgaattaa taagtgtcac aaatcctgct aacatcataa atggcataaa
    97621 tgtagcaaac gcatctcgca aagttcttaa atggatctga ttccccaact tagtcgcaac
    97681 tataccaaat ttttcaaata caatgtcctt cctgctactt ttgcccatat tttttctcct
    97741 ttatgcttat tgtaatcgat tactttttcc acccaaataa tacatcactt atcaaaaaaa
    97801 gtaaatactt ttaattaaat atatatatct tttttagtat aaaaaaataa gctctgaaaa
    97861 aataattttc ccgagcttat ttttcaacaa aaacagcttc aaaaacaaag tcttgatata
    97921 aatgtctcga taccgaatac tcgaaaggtt taccagacga tagagcaaca actttgtcta
    97981 tctcaatcat aaattcacct ggatctattt ttaatatttt tgcgtcaaat tcattcgcag
    98041 tatctccttt gatacgtatg tgcgaagtct ttatttccag acccagttca tttgtgatat
    98101 aagcatatac agatttcttt aaatgttttg gttccaagcc tggtatgact gctaatggca
    98161 tgaatgtttg ctcaatcgag tatggttgac aatcaataaa acggcttcgt acaatattat
    98221 atacatagtc ttttacactg atacttaatt tatcagctac ttttttcgat ggaagttcaa
    98281 ttgagaaagt atggatttct gaatctacgt gttcttcacc aaccacgcta aacaaacctt
    98341 cgtttggacc aagaactcgt gagttatcaa ttggtgttct gacgacttca gtcccatacc
    98401 cacttctact tcgcaaaact ccttcggaaa caagtaagtc tacgcctttc tttactgtta
    98461 acttgcttgt atgataaata actgccaatt catctcctgt aggaagtttc tcaccaattt
    98521 tatactctcc atttacaatt tttttcttta tatctaagta aatttccata tacttcgcaa
    98581 tttttttcaa tggtgaccct ccaatcaaaa acatatcttc atctatactt taacataaat
    98641 aaaccgataa aatccacatc aaaattatac acacaataaa aaagatatat atatttaaac
    98701 aaaactattt actttaagtt gtaagcggtg ttatcattaa gtggaaacag gaggtaaaaa
    98761 aattatgaca actatgaaaa agctaacttt tccagatgat ttttggtggg gttccgcttg
    98821 gtcagctgag caagcagaag gaaaaggaga aacaggaaaa gcagagacta tctgggatcg
    98881 ctggtttaaa gaacaacctt accggtttta tcaacgaatc gattcctcta ttacaaccga
    98941 tcacatccat caatataaag aagatataga actaatgaaa aaaactgggc ataactcctt
    99001 tcgcgtttct atttcttggg cacgaatgtt tccaaatggc ggtaccggaa aagtaaatcc
    99061 caaagccatt tctttctatc gaaaattatt ttccgaaatg aataataacg gaatcaaagt
    99121 atttgccaac ttatatcatt ttgacatgcc tgctactctt caagataaag gaggatggga
    99181 atcacgtgaa gtagttgatg cttatgttca ttacgctgaa acttgtttta aagaatttgg
    99241 tgacttagtt tgtcattggt ttaccttcaa tgaaccactt gggcctattt taggtactta
    99301 tcttgaagat tttcattatc caaacctcat tgactttaaa cgcggagcgc aagcagcatt
    99361 cttcactata cttgcacacg caaaagcaat acaagtattt aaagaactag ctcttcctag
    99421 taaaataggc gttattctaa atttgagtcc tacttttcct cgtagtcaaa atcctgctga
    99481 tgtgaaagca gcagaaatcg ctgatttatt ttatacgcgg agctttttag atcctatggt
    99541 taaagggaat ttttctaaaa agcttatcct gttattacaa gaatataatc agcttcctga
    99601 agattatacg aaagaagatc ttgtatgtat ctacgaaaat accgctcaaa ttcttggact
    99661 aaactattac gagccacgtc gcgtcaaatc tcgttcttct atggtggata catctagtcc
    99721 atttttacca gagtggtttt tcgaaccaca tatcatgcct ggacgacgaa tgaacgaata
    99781 ccggggatgg gaaatttacg aaaaaggaat ttatgatttg tgcatggata tcaagaacca
    99841 ttatggaaac atcgaagcat ttatctcgga gaacggaatg ggcgttgcgg atgaagaacg
    99901 tttcatggat gatacagggc aaataattga tgattatcgg attgagtata tcaaagatca
    99961 tcttgcttac ttatggaagg caataaatga aggatgtaac attaaggggt atcatctttg
   100021 gacatttatt gattgctggt catggatcaa cgcctataaa aaccgatatg ggctggtttc
   100081 actcgacctt actactcaaa aaagaacaat taaaaaaagt ggcgaatttt acaagcaatt
   100141 aagtgataca aatggattta gatacgatgt agacttgtta gttgaataat attctaaaat
   100201 tccacttgaa gtgaacacat tagaaaacaa gaataatgag aaataccaat aacaaatact
   100261 ttttcttcat acttcattta tacttgtcag tataagagac tgtgacaaat gtagtgatcc
   100321 tcagaagtta ggtctggaaa tctaacttga gaagattttt ttaaactacg tccagtcttt
   100381 tttatttgtt taaaattgaa gttgacaagt cttcattaaa aatttagaat attcacaagt
   100441 ttgacgacaa ttatgaaaat ttatgtcgtg ctaaaggagt tttgttattg gatgaaaagt
   100501 tagatataaa aactgcgatc aaagacacgt tacctaccgt ttttggttat atcggtattg
   100561 gacttgcatt tggtatcgtt gggaaagctg ccgggtttca tccgctggtc gtcacgttga
   100621 tgtccctgct gatctatgct ggttctgccc aatttatcac ggtcagcatg cttgctagcc
   100681 atagtccact gctctccatc gttctctcga cctttctagt caattcccga atgattctga
   100741 tgagtatgac gattgctcct tatttcaaga aaaatcggct gcttcaaaat ctgctgattg
   100801 gcacattgct gacagatgaa agtttcgcac tgggaatgaa taaattgaac tatactggac
   100861 aaaagttaaa ctttcgttgg atgaatacag ctaattggat ttcttatttg acgtgggtgg
   100921 gttcttctct tgttggcgca cttttaggga attttattac tgatccgaaa aagtttggtt
   100981 tggatttcgc catcgtcgct atgtttatcg ggttacttta tcttcaagtc atttctgata
   101041 gaaacacctc taaacgatta cagttgatcc tgattggtct cactttgatt ctggtatatg
   101101 tcggactgat ttttatccca agtaacttag tgattttagt tgtaacactg attgggtgcg
   101161 gattgggggt gtggatcaaa catgccttct tttgagttta cattgctgac tattttaggt
   101221 tgtactttag caacttggct ttctaggatc ctaccatttg tcttactgaa aaaattcgat
   101281 ttgccgcaac cgttgcttga gtatttaagt tttgtcccga tcgtcattat gtctgcttta
   101341 tggttcagca gtctatttac ccaaaatatc ggacatctgc cgcagatcaa tctcgaaaat
   101401 gctttggctt cagttcctac acttttagct gctattcttt caaaaagctt attggtgatc
   101461 gtcttggtag gaattctttc cctttcgttg attcgcttat tataaataaa aaaacaagag
   101521 cttatggcaa attactgtca tgcgctcttg tttttatcaa agtcaaataa gaaaaaaatc
   101581 ggcgtattct tgcttatccg ttgaacggac cactaacaac gacttttcct aatatatgtc
   101641 ctgtttctac gtctttggtt gcttgtttca agttcttcgc attcatccca tctgaataga
   101701 ccttgctcaa tgtactgcgg ataatccctt catttgctaa agcagcaatg tgcgctaaag
   101761 cttctccttg cgtttcgatt tcatagttat agtctgtttt agcgaacata tactcccagt
   101821 cgaagctgat agattggttt ttccaaacac ctatatctaa cggctctttg atccctacga
   101881 tcgttcccac atgtccaaat ggtcggacaa ggtgtttgat ttgatcaaag tagcgggtaa
   101941 tatcgaataa tacagcgaca tactctactt gatcgattcc taattcacga aaacttttac
   102001 ttaagtcgtg atgataatcg attggatagt ctacacctgt ttttttcagc cattcaaaat
   102061 tcttcggact tgcagtcgcg tagacttcta ggccagccca atgcgctagt tgattcaaaa
   102121 tcgaaccgac gcccccagct ccgttgatca ctaagatttt tttcccgcgg ttggcatttt
   102181 cttctggagt cagaccaaat ttttcaaata acaattcata agcggtcaat gaggtcaacg
   102241 gcaaggctgc ggcttcttca tctgaaagat tttttggtgc aagagcgaca atacgttcgt
   102301 caaccagttg gtattcttga ttgcttcctg ctcttgtcgt tgtacctgcg taaaaaacgc
   102361 gatcgccgac agaaaatttt tgcacttcat cacctacagc aacaactttc ccgactccat
   102421 caaaccctaa gatacgtaaa gcatttctta tcccgttatc ttggcgaagt ttcgtatcga
   102481 caggattaac agatactgcg ttgactttta ccagaagatc ccgtgaactg ggtacaggta
   102541 tctgttcttt ttcatcaata aagctttttg gatcatcgat cgacaaccct tcataaaaac
   102601 cgactacctt cattaattcc ttttctgaca tacgaattcc tccttagctt catcaagttg
   102661 gagcatccat acagttttca tttcaatata tatagtatgc tatttgttcc acttttattc
   102721 atcataatta ttctcttact taaagtaaac tatttgcact tttttggtta aaaaagaggt
   102781 tgcgacaaga cttttgtcac aacctctttt aaacggtgtt caatcaactg accctcggta
   102841 ttcgctcaaa aaacgacaaa atatgaggag ctatttttgt ttggctgttc ttattacttg
   102901 atgcaggaca gctttttcac gacctctaat tcacggtgtt caagcaagaa atcattgttc
   102961 actgaaaagc gttggatgtt ctttttcaaa ggtgtctaag atctctcgta cttcatcagt
   103021 agatttcgta ttcatcaact gaactcgcaa gtcatttgct cctggaaatc ctttgatata
   103081 gattttaaag aaacgatgta gtcctgtgat ggaacgcggg atgatttctg aataatgatc
   103141 ttgcagatct agttgcagac gaagtagtcc gatcagttct ttttctgtat gttccctcgg
   103201 ttctttttca aatgcataag gattcttgaa aatcccccgg ccaatcatga tgccatctac
   103261 gccatatttt tcggccaatt cttctcctgt ctggcgatct gggatatctc cgttgatcgt
   103321 gatcagtgtt tgcggagcga tttggtcacg taaagcaatg attttaggga tgacttccca
   103381 atgtgcatct actttactca tctctttacg cgtacgcaaa tggacagaaa gattggctat
   103441 atcttgatga agtaggtgac tgatccattc ttccatctca gacatttccg tatagccgat
   103501 acgcgtcttg acgctgacag gcaaaccgcc agctttagcc gcttcaatca attgtgccgc
   103561 tacttctggg cgaaggatca agccactgcc ttttccacgt tctgctacat tagggactgg
   103621 gcagcccatg ttgatatcga ttccttggaa gcccatttct gccatagcaa tgctcatttc
   103681 tctaaaaaat tctggcttgt ctccccaaat atgggcaacc atcggctgtt catcttctgt
   103741 aaaggtcaat cttcctcgta cactgtcttt tccatctgga tgacagaaac tgtctgagtt
   103801 tgtaaactca gtaaagaaga catccggtgc tgctgcatgc tttacgacat ggcgaaatac
   103861 aacatctgtt acatcttcca ttggtgctaa aacaaaaaaa ggctttggca gctctttcca
   103921 aaaattagta gtcatttatt tgttactctc cattctatca agcagtgaag tcgcaatctt
   103981 tctcaaaaac attgtcatta tactaggaaa caaaaaaaga agcaaagtga acagcttaaa
   104041 agatgtttct gattgagcaa aaaaagactg tgacaaaaat cttatcacaa ttccttttcc
   104101 ggaataaatg gtgttcaaaa gcttgcatct gcggtaataa gtccaaccaa acgaaaaata
   104161 ggaggagcta tttttgtttg gctgttctta ttacttgatg cagaacagct ttttcacaac
   104221 ctctccacta aacggtgttc aatcagctga ccctcggtat tagctcaaca aacgacaaaa
   104281 tatgaggaac tattttcccg tttgtttctc taatactcag gtcaaaacgc tgatttcaca
   104341 acctcttttc taacttctca atcctcttcc tttattgatc aaataccaag taacggcgta
   104401 caaaacaacg atgaatagca caagtacgat catcgatgtt gctactggca catcgattgt
   104461 tccaaggaat ccgtaacgga aaccggagat catataaacg atcggattga ctttcgaaac
   104521 agcttgccaa aatggcggca acatagagat ggcatagaaa acgccaccta gataagttaa
   104581 cggctgcaag acaaatgtag gcacgatcga tacatcgtca taagactgag caaaaatccc
   104641 gttgagcagt cctgctaacg aaaacaagat tgccgtcatc aataatgtaa tgatgaccat
   104701 gaaccatgaa tacacatgaa gtggtacaaa gaacaaggaa atgatcgtta cgagagagcc
   104761 gacgagaata ctgcgaccca ctccgccaat cacaaagccc caaatgatca catgcgtagg
   104821 aacaggcgct accaagattt cttcgatgtt tttctggaat ttttgagaga agaaggacga
   104881 agaaacgttg gcatacgaac tagtgatagc agacatcata atcaaaccag gcacgatgaa
   104941 ttccatatat gaaaaaccac ccatgtcacc gatccgacca ccgatcattt ttccgaaaat
   105001 aacaaagtac aaggatgtcg tgatcacagg cggaaccagt gtttggaccc agatacgcaa
   105061 atagcggttc gtttccttga tagctaaact ttttaatgca gtaaaataaa gattaaacat
   105121 ttttctcctc cgtatgatta ttttcttctg tgattttcaa aaacagttct tctaaacgat
   105181 tcgacttatt cctcatagaa agaactttga ttccttgtct tgtcagctga tcgaagattc
   105241 cgttcacccc ttgatttcgt tcaacttcga cagcgattgt ctgttcatct tcaaatgtac
   105301 aagcgtatcc ttcaatcaca ggtttggtct catatggcgc taaatcaaag ataaatgttt
   105361 caaattgcag tttggataga agctctttca tactagtatt ctcgatcagt tcacctgatt
   105421 ggatgatccc gatgttgcga caaagcattt cagcttcttc taaataatgc gtcgtcaaaa
   105481 tgatcgttgt accattttcg ttcaattctc ggagaaactc ccacatctcg cgtctcaatt
   105541 caatatcgac tcctgctgtt ggttcatcca agatcagcaa acgtggttca tgcatcaatg
   105601 ccctagcaat catcagtctt cgcttcattc ccccggaaag catacgtgca cggacatttc
   105661 tcttttccca aagattggac tgcttcaaat atttttcgct gcgtttcatc gcttctttgc
   105721 gagagacacc gtagtagcct gcttgattca cgacgatttg ctggaccgtt tcaaagggat
   105781 tgaaattgaa ctcttgcggg actaatccaa tctgttgctt tgctcggact agatccgtat
   105841 ccagatcata accgaagaca ttcacttttc cagatgtttt attgactaaa gaagtaatga
   105901 ttccgatcgt tgtagacttc ccagctccat ttggtcctaa tagcgcatag aaatctcctt
   105961 ctttcacgga aagatcgatt cctcgcaatg cttcgacccc acttccataa acctttttca
   106021 aattatttat ttcaagcgca tttgccattt atttcctatc tccttataga catgattctt
   106081 tattgtatca tggaatacag cagatgaaaa aacaacttgg ttccagcgaa aaatcaggtt
   106141 gctgggctca ggaaaatctc ctaatgaaag acatcaatcg gacgaagtca gacaaccttt
   106201 tcagaaaaaa caaatcgaag ataaaggatt actattcata tgtgcaacaa aaggagcgtg
   106261 agacaaaagt aaagaacact tttgtctcac gctctaaaca cgtataaacg gcggaagcaa
   106321 aagccaagat ttttgatcca ataaatactt tcgatcactt cgcctatccc aatacatgcc
   106381 actgccgctt ttcatcaaat aacgcggctt ccgtttttgc ggtttctact aaagtctctg
   106441 ggtaatccaa aactttcagc aaggcaatcg catttcgggt ccttgaaggt ccttctttta
   106501 atttgaaatc aaaactgatt ccttttcctt ctgttacttg ttcttcaaag tggacattct
   106561 cacaataatt ctttaaaatc tctgtcaatt cgatatcatg tgtggcgaca aatgctaaag
   106621 atggatactc cgcaagccac cgaacgactg aagcggaaga agcaatccgt tcgatcgtat
   106681 ttgtcccttt taaaatctca tctacgaagc agtagcagcg ttctttggaa gccacttggt
   106741 ccaacaaacg tttgatcgat ttgatttctg aaacaaaata actgtcgcct tcaaataaat
   106801 catcttcgat tgccatggaa gtcaacacat gtccaggttg cagggtaaac tgttctgcaa
   106861 tcgctgtttg gatcgtctgt gctagaatac agctgatggc tatacttttg acatacgtag
   106921 attttcctga tgcattggaa cccgtgacta atgtattctt ctgccagttg accggattca
   106981 ctaccgcttc ttttaacaat ggatgataga tatctttcgc tgtcacaccg ccctcagtaa
   107041 actctggtcg gcaagtgatg ggcatataag tacggtaatt caatattgca gcggctactt
   107101 ctaattctcc cagcaattcc cacagcttga tggcttcagt tgaatgcttt tctaatttag
   107161 tgagaacgaa atgataggag ataaatggca gcatgaacat gatgttgaca tattcaaaaa
   107221 tcaactctgc ttcactccca ctcttcatac gaaatgaaaa acctaattta gggatgtctc
   107281 ttaatggttt agtttgctgt ttcagctctt cttgaagtgg tgtcggcagt tttgctagct
   107341 gattggcggc tgaaatcgtt gaaaccaaat aactcatgct attcagctct gtttctagtg
   107401 tttgtttctt cactagataa tagaccgtat tgaatactaa cccaccgatt gccaaataga
   107461 ttcctagtac ttgtcctaaa agaagcaaac ccaaacccac cagcggaagc aagccaagaa
   107521 aaataaataa acctacgcgt ccaatctttt tactttttcc atccgctaga tattgttttg
   107581 caaaattatg atcttttttt cctaaacgag cgaattgata ttggattttt tctctcagtt
   107641 gaggattttc ctgataaaaa gcaatcagtt tttctaactg ctgatcttca ccaaaatcaa
   107701 agctgcgtaa acgttgatac aacgcttctg aacctacact agaataggta ctgttgattc
   107761 cttcgaatac ttcgaacata tccaggtcat accaagtaag atcatcgatt tcgctatccc
   107821 atgaacggaa cttcttctcc gtgagccatg cttccttcaa gctttcttct ttatcaaatc
   107881 tcggttgata aggaattttt tcccatttgc tacgaactgt ttcctttaat ttcaaacgtg
   107941 aaaaaatgtc taaagcaact aataaaataa cagctgcaat aataattaaa acgataaatt
   108001 ctctttgacc catatccctc tccgttcctt tatttgttag ctttagtata gcactgttgc
   108061 gctatttgaa aagagggtaa aaaaacacct ttcaaaataa aaggtgtttt tttcttgtat
   108121 attacatatt tatctctcat ttatcaaaat tgacaaataa tcatagggag gaattgttgt
   108181 taattcttgt ttattctcca gtgcattgac aactgtccca agggaaagga tagcctcagg
   108241 tactattttt tcttgttctg ttggattagc taagcgaaga acaaatcctt gttcatgaaa
   108301 ataagaagga taaatcgatg atacaattaa gtcttcaggt aattcaatca atgaaaattt
   108361 acgaggaaca tcaagttcat tttgtaatgg ccaaatcttg ttatctaacc tgtgaataaa
   108421 tacattcagt ttctgctttt gataagaaat agattgttct aaccgttttt ctgcctgttt
   108481 tgccactttg aactcattaa atcttccttc ttctacatta aatccaaaag tgactttata
   108541 ctcacctatc tcttgagcta gcggtgtttc catcatgaca tgcccttcat ttgtcgtatc
   108601 tcctgaagct cgcccaggtc gccaagcaag attaggtttt ccaagttccc ctgttgttga
   108661 aaataaggtt atgattaatt gattttctat acgttcatac tcttttaaac catctgcata
   108721 aaacgtaaaa taatgatcat tttctgccac agagacactc ttatcgaata tttctaaatt
   108781 aacaggtttc tctaccatag tttctgacca attcggagga atgacatcag gggtattttc
   108841 aataaatccg ttttgaattt gtgcaattga tttttcagat ttatctaaaa cattaattgc
   108901 taagcgcata cgatgcgagt aaacagtatt atgaattttg agtgtgcctt caacgatttg
   108961 actttctccc agactgaacg atatttcata agatatttct tccatttcgg gtttttcaga
   109021 taaacgatct tttaaatctt taggaagttg agcttttccg taaacaacta atgtttcttg
   109081 taaagaatct ttatatactt tagctgtttc taattttaga gatagttctg tatctccttc
   109141 taatggtgaa taatcatacg tatcgccatc atttgctgaa tcgatcaaat gaacgaaatc
   109201 aagatattgt ctatctccaa ctatcaaatt caattgccca tctttaaaag aaagtttata
   109261 tttattgtta cttatctcag ttttgtctat ctcgattgct gtttctaatt tttcattatt
   109321 tttctcaaat tcaacaacag tgtatcctag tgctggcaca tttacattta tttttatgtc
   109381 aagttcataa taagctggtt catcaaaata ttcgaaacct gtagcaatca tccgataagc
   109441 atttttccgt tctggaaaat aaacttcttt ttcaatgata ttatagggac tacctttgaa
   109501 gtgtattttc tttgaatcag ctactacatg cacgattttc gatccactat aattctcagt
   109561 cgttgtgttg aaaacaagga cttcattcga ttttagcttt aatgcatcag ccatccgttt
   109621 tacaataagg ttttcgattc cgtcagctat ctcattagct tctttgattc gatggaaaat
   109681 atcttccgca acattatctg aaacacagcc accaatacta tcatgagcct ggttttgcaa
   109741 aatctttttc cataaccgac gaagtaggcc tttactgata tggataccat ttctttctgc
   109801 aatcagcatg agcggctcaa ctcgttttag aattttttgt tccaatttaa aattttctat
   109861 tttcattttt gttcttactg agccaataga acgatgaaca cgagagtaaa ccggctgacg
   109921 aagttcacct ttatattcag gtaattcttt tttgtttctg ataacttcta cataagaagg
   109981 ataatctgaa ataatattgt ggaatttact gtatttattc aacttctcta cgacttgatc
   110041 aaaatttaaa atcattgact tttgatctac acccgaaggt actaaaatat ctttgttttt
   110101 tccttgcata tgaagcattt caactgcttc atccaacttt tcttttgcaa attcaggaat
   110161 atctttaatt gcgtctaagg tcatcattcc agtcatataa ccaaatggaa aattcatggc
   110221 ataaacaaat ttatctccca atcctttcca gataaaataa ggagatggaa ccatcgtttc
   110281 aaagtttaat cctcgccaac acatgaaatt atcgatttct acttgatgca aaagtgtagg
   110341 caaattcgca ttgaacccaa acgtgtcagg caaataccct accatcattg gatctccata
   110401 tttaaggatc gtatcactga ttccaatcat taagtttctt aaaattgatt cagcatccac
   110461 taataaggca tctgtttgtg cataccacgg tcccacgaat agttgtcctg ttttcatcag
   110521 tcgttggata accttaagct tttgcggatt gatctccaaa tactcatcga cgattgaagt
   110581 ttgtccatct aaacaaaagt ttactttagg gttcctttcc aattcatcta gaacttcagt
   110641 aaagacctga tcagacaata cgatggcatc ttcatttgta aaataccatt ctctgtccca
   110701 gtgcgtgtgt tgaattatat gtgcatttac catatcagat tctcctactt tccttcttct
   110761 actgaattta cttgttgttc ttttttatac ttgatggatt ttagtgcatt gaccattaac
   110821 gctgtaacca ctcccccaat aacaattgat actaaatata aaggtatatt cgtaacaaaa
   110881 ggaattgcca taaaggttga aagcattgtt tcttgagtaa caccaaaaaa tccatttaga
   110941 ccacatgcta ctgcagtgcc caccacgatg cttggtatta ctcgtaaagg atctttcacg
   111001 gcaaacggga tcgtcccttc agtaatcccc acaaggccca taatcatagc tgtctttgca
   111061 ttatctcgtt ccgattcatc ataaagtttt ttgtttaaaa ttgttgctaa aaacattcca
   111121 aatggcggaa tagcaattcc taataacatg gctgtactag gtccaaagct tccgcttgaa
   111181 aaagaagcaa ccccaaaagc atatgcgatt ttattgatag gtcctcccat atcaaacgcc
   111241 atcattcctc ctaaaatagc cgacatcaaa gcagcatttg ctcctgacat gccttctagc
   111301 caattagtca gtcctgttgt cattgcttga ataggcgtag ctagtacata ccataatatg
   111361 attccaacaa ctaatgtagt aacaaaagga atcagcataa ttgattttag actaataact
   111421 tgcatcggta cttttacttt tttcaatgca ttagctaaat agccacaagc taatccagca
   111481 accattcctc caataaatcc cataccaaga ttttgacaca tcatcccagt gataaaagct
   111541 ggtgctagac cgggacggtc agcaattgaa tatgcgatat aggctgaaat catcggtacg
   111601 ataaactgta atcccgtctg accaatcatt cgcaggactc cccagaatgt atccgtctgg
   111661 tcccaaacac ctgtgccacc aaaaatgact gcaatagaag ttagtaaccc tgctgctacg
   111721 acaagcggga tcatatagga aaccccactt tggaaatgat ttagaatttc tcttccttgt
   111781 ttcttgaatt ccattagtaa ctcccccacg atatattttt tatttgttaa ttaatgcaat
   111841 tgcttcatca atcgtctctt caccatcttt tactacctct gaggtcccta ctgttaaaat
   111901 cggtttaccg tcaaagcgac ctcgttctga aacatttgta tctactgcaa atatgacaac
   111961 atctgcctcg gaaacatccg aaattgaaag tttgttttct atccccatag ccccctgtgt
   112021 ttctacttta atatctaacc ctttcttctt cgcaaacttt tctaaattag cttttgccat
   112081 ataagtatgg gcaatccctg cgatacatgc tgttactgct actatttttg tcatatgaaa
   112141 ttcctccttt taaaatgata gagcttttac caattctttt ttatttctcg aatcttttat
   112201 tcttttaaca aactcgtcat ccatcaatct tccagataat tctgctaaaa tacgtaaatg
   112261 attagtacct ttatcagtgt cttttattgc taacaaaaag acgagatcaa ctggttgatc
   112321 atctaatgcg ccccattcaa cagaccgctt taacttggct acagccactg ttgattcaat
   112381 tactgctagg cttttgccat gaggaatggc gatatttttc ccaattcctg tggtcatatg
   112441 gttttctctg tcaaatacgt ctttttgaaa ttgtttgtgg tcagacacaa acccattagt
   112501 ctctaacaat ttcgataatt tttcgactac acttttttta tcagatgcat ttaaatctat
   112561 cactatatta tttatattga ttttttcact gatcatttat aagccttctt tcaatatata
   112621 aactaatttt tcaaacgacg aactcgtttt taaatttgct aataactcat gattcgaagc
   112681 gatttcattg aatgtttcat aaattttatt caattcaggt tttacttttt cattaagtgc
   112741 aaaaaagaaa acagaatgaa caagtgtccc atcccaatca attccttctg gattaacgta
   112801 gacacagatt actggctttt ttataaaatc tacttcgata tgcggcatag caaaatcatt
   112861 catcgctgtt gaagatagtt tttctctttt gattgctccc tctagtatcc cttctttcgc
   112921 gtaattttct tttaccaatt ttttggtaat tatatttaaa acgttcactt gattatcctt
   112981 tatttggtgg gtaaaaaagc aaaatcgttt atctaataaa tttagaaaag catcttctgt
   113041 ttgttcattt aactgtagat actgttttac ttttctgaca tctgccccta acatcaaagg
   113101 actaacaaca ataacaggaa aatttgtatt ttcaatcgga atcgtgctta taacaagttc
   113161 atcagtgact tttctatctt gtagttcatt gatgcttagt acatcttcta tctcaaccat
   113221 atctgcaaaa ccgttattta ttctttgctc taataatttt gatgttccat atccgctact
   113281 acaaactaat atcactttcg ttttgtcagg tttgtaacga tccaaaagtg attgaatatg
   113341 gagtgttacg taagcgattt catcttcatt aaaatgtata cagaatctct cttcgatttc
   113401 ctctaataaa tctacactta tcataaatga ccttttaaaa gaatatttga ttttgtccgt
   113461 ataagggtta tagatattta ctcccaattt gagtctttta actgctgcat tgagatgtaa
   113521 tactagatta ttgatcaatt cttcatcagg ataaaattca tttaatttaa ttcttactaa
   113581 ctcttgtagc tcaacaccca tatctaaata ggaaagcttc gtttgatcta agtcgtgatt
   113641 catagcattt ttttcaatcg aagtaatgtg aatgtcaaca taagcttgtt catctattgg
   113701 cacaataatt gaaaatgctt tttcaatcat tttgattaaa ataagtgtat tctttgagat
   113761 ttcttcttca gaattattac tacgtgataa gaaattgctt gtttcaatcc tttctatcgc
   113821 aatagcaagg tggatagcta aagtttgaaa ttcataatct gtaaatttca attgtgtctt
   113881 attcatgtat cgattaagca attcggctac ttttttcaat atgtccttat ttaagaaatt
   113941 attcgcttca ccaatgaaat tgatattcaa gtctaagaga tctgttttac tgttagatgc
   114001 tgtaaagcca ccccaataat agttcacaac ttctgacatc aaccttcttt tacttttttc
   114061 atcagctttg atgcgcacgc catttcgatc tgaaactaag gacatcccat gcttgtttag
   114121 tctttttcta acatctttca ttgtgctttc taccgtcgac ctgctcacgt ataattcgtc
   114181 agcaagattt tgaatcttta gagaatcatt agtattcaat aatttagcaa acacataagt
   114241 tagacggtcc tccggagagt ctgcgatatt gattttatga ctggataata aatttcgaag
   114301 tgtttctttt tttccaataa gcgaaacgcc ttttttaggt tgaaccaaca tttgtacatc
   114361 tggcattttt tggattattt ctttcaaaat taaaatatct ttgctaattg ttttcgtaga
   114421 tacatataat tgttctgata attctttgta agttgtgtgc tcattttcaa tcaaaaagta
   114481 tagtattttc atttgccgtt cgctaaattc gatgcccatt atcttcacct cctgaataca
   114541 gcttaagtgt acaattatta tctctatttt catacagaag aaagttcttg attaatgtag
   114601 aagtttctaa tattcttgat tatttcaaat caataaaaaa gcctgcaata tttatatcac
   114661 aggctttttt ctctattaaa tatatataag ataatacatt tttctactag ttctcactaa
   114721 tcttgtataa ttaaaccctc cgcaacttga cggagatgga gaagatgccc ccgtctaatc
   114781 tagcggtcat ctctcctccc attccttcca ccaatttttt tgacaggtaa agcccgattc
   114841 cgctagattc cgtatttgtg cggctggtat tttcggtata aaaacgctgg aagacttttt
   114901 caacagaggt ttgcgttcct ggtttgatag gattggccac tgttaatcga atgaatggat
   114961 cctcttttga aaatgtcacc tttgcttgtc catctgcata acgcaataaa ttctgtatga
   115021 tattttgcag cactcgcagc aacatgagcg gatctgctaa tacagttgta tttatcgagt
   115081 gttcagcgaa cgctacctcg atatttttct cagaaaattg ttcataaaaa gagaaaaata
   115141 cttcttccac ctctttagaa aaagaaagcg tatggagatc catttctttt tgcttcgtct
   115201 ctattcgagc aagatcataa aactgatccg tcatactgag taatcttgca acagattgtt
   115261 tgatgatcgt taaatacttc tcccgtttct ccgtatcctc tacctgttcc agtaattgta
   115321 cataaccgtt aatagcagtc aaaggagttc tgagatcatg agaaaggccg acgatcgata
   115381 gtctgatgtt ttcttccatt tcttgaaatg cttgtccttt ttgttcattt tcatccaacc
   115441 atgtattcag tgcatctact aggtccatta gattcttttc tcgaaattcg actgaaagac
   115501 gaccaccata ttcttgtcgt tcagaaagag tggcgatttt cttagttaat ctcttgattt
   115561 ccctttgcag gaagaaaata aaacttccca taaagataac aacgagaagc aacagccatt
   115621 taatcaaatc taaaccccac tccccacacc gtatgaatat acacagcatg tgcctttgct
   115681 agcttccctc gaagattgga aatatgcata ttcactgttt tctcactatc aaaatatggt
   115741 tcttgccaaa ctgtttcata aagatttgct cgcgaaaata cttttttcgg atgttctaaa
   115801 aaaagcttca gcagatcgaa ttctcttcct gtcaaatgga cagccacacc attcacattt
   115861 acatccctcg actctttgtc cagtaagatt tccttgtaat agatgcgttg cgacagatct
   115921 tttacttgga cagaagtctg atgacgaagt tggatgccga ttcgtaacaa aagttcttcg
   115981 atatcaaatg gtttcgtcac atagtcatcc gctcctgctg ccaacaagga aactttatct
   116041 ctttgatcgc tttttgctga aagaacgatg atcggaacat tcgatgtctg tcggatttct
   116101 gctaacaatg cttcacctga aagccctgga agcatgagat ctagaaggat caaatcgaca
   116161 ggatatgtgc ttaacaataa ttttccttcc gtacctgaat aagcatcaag aagtttgtat
   116221 ctctgttcaa gaacctcctc cagtaaggaa tgaacagctt catcgtcttc gataatcaaa
   116281 atagtttcca gcaggaccac ctacttaatg tcagattttt ggaaaataaa cattcctaga
   116341 gctgatgata ccacgattgt tactagactg accagaatca ttttcggtgc ttgcgaataa
   116401 gttgcttgtt gcgcaaagtc cgtatacatg agccacgttt ccgtaaacca ctccgttaga
   116461 aattccaagc ctttgatttt tgcgaaaaca ccgggaatga aggccgttcc catgatataa
   116521 agaaaagaaa gaagcaaact gacactggta cttctagtga tgaatgtcaa agccactgga
   116581 acagataatg tccctaatgt cagcagaagc aatacaggaa atacttttag aacataattt
   116641 ccatagtttt tgattccctc aacttcacca aatccgaaag caagtgtgta agcaagcatg
   116701 gctagtcccg tgatcaaaac cacgccaagt gttgtgatca aaagcgtaac gagaagtttc
   116761 gacacataat aagtcattcg attccgtcct aaagataacg tattgcgaat cgtaccgttt
   116821 tgaaattctt ccccaatata aaagcacgca aatgctgcga aagccagaag aatccatgca
   116881 gccatttttt ctaccattaa aatccctgtt gcaccgttga tgactgtatc cgttgcttgg
   116941 tttaattcat tgccgtattt tgtatgcata taccattcgt tccaagaata aaaaagcgga
   117001 agtacgacca tcagtcctag tgagacccac attttacggc tcttccatac ttttattttt
   117061 tcagcagtta atagattaaa catgtggatt gcctccagtt aattgtaaga aataatcttc
   117121 cagtttttgc ccaactaggt gaataccatc cacaggaact tttgcttcta ccaatgcttg
   117181 attgatggct gctacttggt caattccttc aaaaagctgg ataacacggc tagattgtac
   117241 aaaataatcc ctataaccaa gagagtcgag aaccgttact gcttgttccg tcgccgaagt
   117301 gtcaattttt ataaattgac gagattcttg tgccaattct tctttcgata attctttgat
   117361 caagtgtcct tcatgcaaaa taccatagtg agtggcgatc tgtgacaatt catctagcaa
   117421 gtggctagaa agcaagacgg tgatgccccg ttcttttacc aaacgttgga tgatttctcg
   117481 catttctgcc atccctgctg gatccatccc attcgtcggt tcatccaaaa tcaaaaattc
   117541 tggattcgtg atcagtgcat ttgcaatagc taaacgctgg cgcataccta aagagaaatt
   117601 ctttgctttc tttttccctg tattttccaa tcgcatcatt ttcagcaggt cttcgatttc
   117661 tctatccgac acaccgccgt tcgctgcttg gatacgtagg ttatctcttg cagttaattc
   117721 tggataaaga gcaggggttt caatcgattg acccatacgt cgtcttgctg cctgcaaatc
   117781 cgtcgttcca aataattcga tcgaaccttc atcaatcgag atcaaaccca taatagttct
   117841 cataaaggta gacttacccg ctccattttc cccaatcaat ccatagatca ttccacgttt
   117901 gatttcgatt gatactttat ctaatgcttt ggcagcaccg tattttttgg ttataccagt
   117961 tgctttcaag accgtttcat ttccaaaatc catacttatc cttctttctt attgatgagt
   118021 gaagtatagt tgacgggtat aaagaaagca gccagaaatg tataaagaaa gtgtaaattt
   118081 tccaattgaa tgtcaaaaaa aacaatcgga caatacgtgt ctttcctatt atcaggcagt
   118141 ttgttatacg cttgtatcag tttcctgatt ctttcttttc gaccaaagtc gtttctctgt
   118201 attcctcttc actgaaaatt tttgcttctt tcagatcaag cttgagtaat tttaccagac
   118261 cggttataag gataactata gcaagactcc ctcccagaaa aattagactg tctcgcagac
   118321 gtggttgcgt tgtcttccaa tcaaagagcg caccaaacag tgctaatcca agtggactgg
   118381 ccaccatggt aatcgttgtt atcgttgaca taagtcgtcc ttgtatatgc gttggaactt
   118441 ctcgctgaag ccagaccata taaaaagcaa aagaaaacat taatccttaa aaacggactt
   118501 atgaaaaata atacatgccg tttgggattt acaattagct accaaataag aggttatgac
   118561 aaaagacttt tcacaatccc ttcttccgaa taaacggtgt tctcctgcca actcctcggt
   118621 cacaagtcac aatatttatc aaacatgaga agcaattttt gtaaattcct tcttatttct
   118681 tgaagctgac cacttctgtc acaacctcag aagcggataa ataatattgt ttgatgatac
   118741 tttatctttt tcccgtttgt ttatagatcg aatgatatta tagaccaaga atcctaccta
   118801 ttaacatagc taaaaacaca aaaaaggcac tttccaaatt gtggaaagtg ccagaaaagt
   118861 taggattaag gtaactgcgc tcagcattgc ttcgcccagt acgattctcg taactcgtga
   118921 actcgaacga taatcgcaat taacgttttg agaactgtga agctttacgg gctttcttaa
   118981 gacctggttt tttcttcgta tcattgaata agtttgaaaa accttgattt ataaaggttt
   119041 tcccgtaaat atattttatt atatttgatt aaatttgaaa tgtttgtgtt ctaaaatgtg
   119101 ttctaattta aaggcagtat atttcgtatt ttagattaaa tttttaggct cattcattct
   119161 caaatccatt ctattcagtc aataaaaatt ttaaaaagac tttataaaca aagatgttca
   119221 agcgagcatc ttattttttt gtgcttaatt tgaaaggaga acatttcatg tataaaaaac
   119281 aaaaaaagaa attatgtgta ttaactattt tgagtttggc tgttcaagca attgttggag
   119341 caattgctcc tacgattact tttgctgatg aaattaccca tccacaaacg gtaaccgtag
   119401 aactagattt agcacatcaa tatgctgttg aaggaacttt tagtgatggt cgtccaatgt
   119461 cagaagtcac tgttccgcat tatgcagtgt acaacggctt taaacaagat attttctgta
   119521 ttgaaccagg agtcccgatt tacaatgagt tcactcctgg ctatgagaaa aacccgttac
   119581 cagatatgtc cgataaagcc aaattagttt ccgttttatg gaaaaaagta ggtacagatg
   119641 cagatactca tattgtggca cagaagatga tctggcaaga agttaatggg tatacccttc
   119701 actcaataaa acgatcagat ggtagtgccg taaatatcgc agccattgag gcaaaaataa
   119761 atcaagccat tgacgattat cagaagaaac caaccttcca taatagtacg gctaaaacag
   119821 tattagggca atcgactact gtgacggata cgaataatct gaatttgtca gagttcgatg
   119881 aggttgtgga aaatgccgca aacattgatt atcgtgtgaa tggtaatcag ttgataatca
   119941 ccccaaatgc caattcaaaa gaaagtggtg tgctgacgct taagaaatct gctggtaccg
   120001 gaacacctgt cgcctataaa aaggctggcc aacagacttt aatggccggg gcgattgata
   120061 aacctaatac ctacacaatc aaaattgatg tggaaacgga gggttcttta aagatcaaaa
   120121 aagtcgataa agaatcgggt gatgttgtac caggaacggt tttccattta gactttggaa
   120181 aaactttacc tgcaaaagac gtgactactg acaaagaagg cattgctaca ttggatgaga
   120241 ttcctcatgg tacaaaagta accattaccg aaaaatcagt accggcgcct tatacgattg
   120301 ataccacccc catgactacc accattaaag caggcgaaac catttacgtg acttcaaaaa
   120361 acgcacggga aaaagggcaa atcattctgg ataaaagcgg agttgaaaca gggagtgatc
   120421 tttggaatga caattattcc ttagctggta atacgtttgc cattcgcaaa gacagtccaa
   120481 ccggtgaaat cgttcaagaa atgaccacgg atgaaaacgg tcatgcggaa acaccaaaag
   120541 agattgctaa tgcgttggaa ttgggaacct attatgtgac cgaaactaaa gctagtcatg
   120601 ggttcgtgaa tacgttcaaa cctgtaaaag tcgaattgaa gtatgccaat caaaccgtag
   120661 cccctgttac cagtaacgta aaagggcaaa atcaagaagt cactggcgaa accactttga
   120721 cgaaagaaga caaagatact ggggataaag cacaaggtaa ggcagtcttt gagggtgctg
   120781 aatacacctt gtttactgct aaggatggaa aagctgttaa atggagtgag gcttttaaac
   120841 cagagttagc gaagggaacg aaaggttctg atgaaacggt cactttgact ttagacgaaa
   120901 agaaccaagt tgccgttaaa catttagcta tcaacgagta ttattggcaa gaaacaaaag
   120961 cgcccgaagg atatagcctt gatgaaacaa agtatcctgt atccatcaaa aaggtggatg
   121021 atagcgaaaa aaatgccgtg attacccgaa atgttacggc aaaagaacaa gtgattcgct
   121081 ttggctttga tttctttaaa tttgctggat cagctgcggg cactaccgaa actggcttca
   121141 atgatctgac ctttaaagtg tcgccattgg aagggaccaa tgaaatcaca ggtgccgaag
   121201 atgaagcgac cacagcttat aacgagcaat tagggtttga tggttatggc aagtttgaaa
   121261 atcttcctta tggggattat ttacttgaag aagtagaagc cccagaaggt tttcaaaaga
   121321 ttacgccatt agaaatccgt tctactttta aggaaaacaa agaagacttt gtgaagagtg
   121381 agtatgtctt taccattacc gaacaagacc aaaaacaacc aattaaaacg gtgaccgttc
   121441 cttacgagaa gctgacgaac aaagcatttt ctgttagttt gaaccgttta atgctctatg
   121501 atttgcctga ggaagaagat agtttaactt ctcttgcgac ttggaaagac ggaaacaaag
   121561 aattaacttc tctggattct accgagctag ttgataaatt gagttacaat ctacatgaaa
   121621 tcaaagaaga ctggtatgtg gtagcgcaag ccattgatgt ggatgcgaca aaagctgccc
   121681 aagaaaaaga tgaaaaagcc aaaccagtgg tgattgcaga aacaagcgca acgttggcga
   121741 acaaagagaa aacaggaact tggaaaattc agcataaatt aaccgccgaa caagttttaa
   121801 ataaaactat tgtcttattc aactatgtgt atgaaaataa ggaagctttt gaagcaggcg
   121861 ataagccagt agcgaaggat gttagcttga ataaccaagc ccaaactgtc agttgtacag
   121921 tggaacacca tgtttctatc caaacaaagg cccacctaga aaacggttct cagaccttta
   121981 ctcatggtga tgtggtggat atgtttgatg atgtgtcgat tactcatgat gtactggatg
   122041 gctcaaaaga agctttcgaa acaattctgt atgctttatt accggatggt acaaacaaag
   122101 aaatttggaa atctggcaag attgattatg aagtaaatga taaagaattc accaaaactg
   122161 tgcttgcgaa aaaagtagat accggaaaat atccagaagg aaccaagttt acttttgcgg
   122221 aaatcaatta cgataaagat gggaatatca atggaaaaca caatgaagat ttgaaagaaa
   122281 aatctcaaac cttaacacca aaagaagttc caaccatact aagtacgccg aaacaaccgg
   122341 aaacaccaac tgttccaagt ggctctcaag aatctagtcc cacagtgaag accttccctc
   122401 aaaccgggga gaaaaattcc aatgttttac tgttcattgg ttttactttg atttttgcga
   122461 cggcgggcta ttatttctgg aatcgccgga actaaggtga tgagatgata caagtaaatc
   122521 ctaagaacca acgtgcgcga ccgcctccta aaaaagtagt cgcgctattt ttgtatccaa
   122581 aactaacaat gaaaagagga aaagaagatg gaattgaaat ttgtcgtgcc agatatggct
   122641 gaaacctttg gaaagttaag ttatgccggt gaaggagaaa ttataacaga aggatatgga
   122701 cggaatacta cggtgattgg tcgcagttat catttgtatt ccagtaagca acgggccgat
   122761 gatattgagg tggtagtagc tgcggaagcc ggtgaaaagg attttgatca agaccaaccg
   122821 ctaaaagccg tgaatcccca tttggttgcc aaaggctatg agattgagaa tcgtgggttt
   122881 actgattacg tgttgtatgt tgatgattta gtgaaagcat aggaggaaaa gaagatgaga
   122941 ttaacagaag gtattgtcgt agattcaggt ttaacatttg ggaagttgcg tttttccgca
   123001 ttacgccgag aagtacggaa gcaaaatgag gatggaacaa ttggtaatga ggtaaaagaa
   123061 cgaacctata atttaaaatc ctctgcacaa gggcgaatga ttcaagttag tatcccagct
   123121 aatgtaccct tacgcgagtt tgcttatgat gcagaggtag agttggtcaa tccaatcgtg
   123181 gataccgttg ccaattatgt ttttcgagaa ggaactaccg ttaattggtt cattaaggcg
   123241 gatgatttag tcttgaagcg gcagccgaat caaggaaatc ctacgaacca aaatgaaaga
   123301 aagaaatagg tgaagattat ggaaattaat gttgaacata ttttagattg tctcgatcaa
   123361 tatggaaaag gcgagctgac tgaggaacaa ctcgttaaag cattaacctc tgatgaaaaa
   123421 atgtttctga ttatacatca aggtttactt ggagaaaata gcgacagtga agaagactct
   123481 gatgtactag actggttagg agaagaagag tctttcttta tagttgtcga agtaaatgaa
   123541 aacttatgtc ggcaggcaga atccattttg gaagaaattg gtgtggagat gccggatgct
   123601 attgaaggct ttttaaatca attggttgaa acgaaacaac tcccctcctc gtagcagtaa
   123661 atgactagca taactttttg aaattgccta atgaaatcct attgggcttt ttcgattgga
   123721 ggtggaaacc atcaaaatgt acaaaggaca tcgcatacgc gcaggagatc agcacttggt
   123781 ttatcacttt gttcttggct ggctactcgc tctgttcatc ggttggatga gcgtctttta
   123841 ttttcaagag tttagacaat ttgatatttc taagctatca ctttctacta ttgaaatcgt
   123901 ttggtctata aaagatttag tatgtctgct tggaagtctc gctttttcag gagctatgat
   123961 attgctttat attcactttt ttcttgatca ttggcgaagc ttgtggcatc gacaaaagct
   124021 agctcggatg attctagaga accattggta tgaagtgaaa caaactcaaa gtgaaggctt
   124081 tttcaaagat ttgaatagta gccgaaccag agagactatc agttacttcc ccaaaatctg
   124141 ttatcgaatg aaagatggat tactgtctat tcgcgttcaa atttcacttg ggaaatacca
   124201 agatcagctt ttaaaattgg aaaagaagtt agaaagcgga ctgtattgtg agttagtaga
   124261 aaaggaactc aaagactcct atgtggagta tactttactg tatgatatga tcgccaatcg
   124321 aattgggata gacgaagtag tggcagaaaa tgggactctg cgattgatga aaaatcaagt
   124381 atgggcttat gattctttac cccatatgtt aatcgctggt ggcacgggtg gagggaagac
   124441 ctatttcctc ctcaccatta tcgaagcact attgaagtca gatgcagaat tgtttatcct
   124501 cgatcccaaa aatgcagatt tagctgattt aggtacggtg atgcctcatg tttattcaca
   124561 aaaggaagaa atttctgctt gtgtggaaga tttctatgaa cgtatgatgg ctcgtagcaa
   124621 ggcaatgaaa gaaatgtcta actacaaaac aggagagaat tatgcctatc ttggacttcc
   124681 acccaacttt ttaatctttg atgaatacgt ggcttatatg gagatgttaa cgacgaaaga
   124741 aagtgcggtg attttgaata agctcaaaca aatcgtgatg ttgggtcgtc aatctggttt
   124801 ctttctgatt ttggcttgcc aaaggccgga tgcgaaatat ttaggagacg gaatccgcga
   124861 tcaattcaac tttcgcgtgg ctttgggtcg tatgagtgaa ctcggatatt ccatgatgtt
   124921 tggggaggtc gaaaaaaact tctttatgaa gcacatcaaa ggtcgaggtt atgtggatac
   124981 aggtggcagt gtgattagtg agttttatac gccacttgta ccaaaagggt atgatttctt
   125041 agattcaatt agtaaattag aaaagatgaa tgattgagtg atcttcaata ctgactttat
   125101 acttcaagta acgtataata cttttatata gtaggaagaa aggggataat taatatggaa
   125161 agtaatgatt cttatttaga gtatgcaaaa gcaaataagg ataagtttat ttcttatatt
   125221 atcaaaggga aatcccccga agttggacga gacgcagttt ttatggcagg gagtcctggg
   125281 gctggaaaat cagaggttgc cattggatta gctgagaatt atgataacca tgtgattatt
   125341 gatgcggatt actttcgcac ccagtttcct gattataatg gaaaaaactc tagtctcttt
   125401 caaaaagcat cttcttggtt ggtagagcag gcatttagat atgtcttaga tcatggctat
   125461 tcttttattc tggatgcaac ttttgcaata ttaagtgctg aaaaaaatat ctcgcgggcg
   125521 ttgaaaaaac attttcgagt gacgattttc tatgtttatc aagaccctaa aatcgcttgg
   125581 aaatttacac aagaacgtga aattgcagag ggacgtcatg tgccgaaaaa ggcatttatt
   125641 aacgcttttt tcaaatcaag agagaacatt gcaaaagtaa agagtaaaca tccagatgta
   125701 ttgcttcata tcataataaa agattatacg aataatattt ccgaagttca ttatgctacg
   125761 gataatctag aattattttt accactaggg tatagtagga aagatttgga ggttcaatta
   125821 catgactgag aaagaacaag taacgaaaat tgtaaagaaa tacaataaga gcattgcgga
   125881 tttatcggaa aatgctactg caaaagagtt caaaacggtg attaaatatg tagccgatca
   125941 ggccaatgaa aaacaacgga aattagttgg attaaataaa aaatagtagg acaaattaat
   126001 aatgtatgag ccaagagcaa aatgttcttg gcttttttct ttgcaatgaa tgaggtaatg
   126061 tatgagattt ttagatttat tcgccggtat tggtggcttt cgtttaggta tggaacaggc
   126121 gagccatcat tgtatcggtt tttgtgaaat tgataaattt gctagacgta gttataaagc
   126181 aattcatgat acaagtaagg aggtggaaat gcatgacatc acaagtgtat cagatgagtt
   126241 tattcaatcc ctcggaccag tggacatcct ttgcggcgga tttccgtgcc aagctttttc
   126301 aattgcggga aagcggcaaa gattttccga tactcgaggt actttattct ttgaaatcgc
   126361 tcggttcacc actcttctcc gacctaagct tttattcctt gagaacgtcc gaggattgct
   126421 caatcacgaa ggaggggcta cgttcgagac gatcctccga acgctggatg gattggggta
   126481 tgacgtggag tggtaggtgc ttaactcaaa ggcctacatt ccccaaagcc gggagcggat
   126541 attccttatc ggacattctc gagacgcatg taccgaacaa gtatttccta tcattggacc
   126601 gtcttcaaca tctgatcaaa acatcagaaa tttggtaaat atcaatcctt ccaatcgagg
   126661 aatgggtgga caagtctatg gttcagatgg cgtagcgcca accttaacag gtgatgaagg
   126721 aatcaaaatc gcactgccag caagggatgg aatctctgta gcaggactat taccgggaaa
   126781 gtttgaacaa ggtaatcgag tttatgaagt tactggaacc gcccccacct tgtcaacgaa
   126841 acaaggtggt acaaaaatca tgattcgaaa aaatgaaaca gaatatcaag aggtgaagcc
   126901 agaagacagt gtgaatctgg cttttcctaa ttccacaagt cgccgaggtc gtctgggaaa
   126961 acagagtgtt cataccttac taacaggaga ccaacaagcg atcgtcacgg atcagtatca
   127021 aattcggaag ctaacaccta gagagtgttg gcgacttcag ggctttcccg attgggcttt
   127081 tgatcgagat tctcaagtca attcagatag tcagttgtat aagcaagccg gaaactctgt
   127141 aacagttccg gtcatttttg atattgccag aagattaaaa gagttggatg tacatggttt
   127201 atgatgagtt gattggagaa atttattggg tgattggaaa gattcagtca gacccagaat
   127261 tagaagaaca attgcgacgg ttaaaatttg atattcgcaa gaatggtgtc aaagtcgctg
   127321 gcgatccata tttaatgaat gaggagacgg atgctcgaat tgaaataaat caagtaattg
   127381 cagaatttga gcggattgcg gaccaagcaa aagaaccaga tattcgtcaa tacttgttag
   127441 aaatgaaagc agagttggaa gtaaatggta ttacagatga gtaacctaaa ccaacacaac
   127501 tgactgttag gcgctgaccg cggaggattc gcgaagcaga aatcctccgt ggtgctgtgc
   127561 ctgttcatgg acggcgttag ccgaccatga tgtctcaccc ccgtatctaa caggggggta
   127621 caaaaacaca aaaaataagt aagcaaccat taagaatgct tgttgtatca aagatagtaa
   127681 gtaatttgta taggtgttaa ctcatttgaa aaagttaaca ccttgaattt ggaggtgaga
   127741 acttggcaca acggaattta gattatcggc tattaaaaga ccgacgcaac gaatacggcg
   127801 tttcacaaaa taaattggct acggcttgtg gacttagtcg gccgtactta aatcagatag
   127861 aaaatggtgg cgtaaccgca tctataaaaa ccatgaggaa aatttttgac caactggaaa
   127921 gctttaatcc cgatttgcct ttgacgttac tgtttgacta tgtaaggatt cgctttccca
   127981 caacggatgc acgaaaaatt attcaagaaa ttctccattt gaaatttgag tatatgctcc
   128041 atgaagatta tgccttttac tcctatcaag aacagtatgt catgggtgat attgtggtga
   128101 tgttgtctca tgaagaagat aaaggtgtgc ttttagaatt aaaggggcga ggttgccgac
   128161 aatttgaaac ttttttactc gctcaaaagc gtagctggta cgactttttc gaggattgtc
   128221 taaaggccgg tggcgtgatg aaacgcttgg acttggcaat caatgatcga gtggggctat
   128281 tggatatacc tgagctaacg aaaaaatgtc agaaggaaga atgtatctcc ttgtttcgta
   128341 cctttaaaag ttatcgttcc ggggaacttt taaaggctga tgaaaaggac ggcatgggca
   128401 ataccttata tatcggcagt ctcaagagtg aggtttattt ctgtttgtat gaaaaagact
   128461 atgaacaata tatcaagtta gggattccat tagaccaaac tgagacgaaa aatcgttttg
   128521 agattcgact gaaaaatgac cgtgcttttc atgcgattca agatttgtta aaaggtcgta
   128581 gcattgagag caccacgttt tccattatca atcgttactt gcgatttgcg gataaagtag
   128641 aaggtaaaag gcgaaccaac tggcccttga atgaacaatg ggggcgtttt attggacgga
   128701 atcggaaaga gattcaatta acttccgagc caaaaccgta taccattgaa cgaaccttga
   128761 attggctagg ccgacaagtc gcccctacgt ggaaaatggc taaggagttg gatcgattga
   128821 atcggacaac ctatatccag gatatggtac agaatgcacg cttatcagac cgacataaaa
   128881 agattttgga gcaacaaagt atggcaattg aaaatttgat tatatgaaaa gaggaatcgt
   128941 catgggaatt gtaaaagata tttttttggt atttggtggc agtatgcttg gtgttactgt
   129001 gatgtgcttg atgaatgcaa gtgcagcagc ggatcgagca atggaaaaga aaggaaagtg
   129061 acaagatgaa tttcggacaa aatttatgtg cgactcgttc cttagtgaaa agctaaggca
   129121 ctaataaaag aacgaaaaag tttggttatt aggagaactg ataatctgac aggtggaatg
   129181 atgaagtaac gctctgaaac gcctgccctg agcctccgac aagcattgta tgaggaaact
   129241 cagaatgttt gaagctcggt aaagacggct gaaagatacc gtaatagttg atgaacatat
   129301 atcttctatc gaaaactatc cagaggtggg tagcgtatcc aacaggtcgg gggtctataa
   129361 aatatctatg gttagaatgt tctataagga actgacgaaa cagcgaatgt acgggtctaa
   129421 atttgaactt tgtagaaatg caaaggtacg agaaatcgta gctggtgtgg caaagtaaga
   129481 atataggtta tgaaatgcca tataacgtta caggcggtat caagccagca ggcttatagc
   129541 tagtgaccta aggatatata tgtatagata agattatcgg aacgaggaaa ggtattgggt
   129601 tctcatcaag agaataaact gacgaagaac aataagcagt tgaactaatg ctgaaaagca
   129661 gagggcgaac ctaagaaatt cttgtaatga gaatggagga atgccctcaa gtcgtgtata
   129721 tattagaaaa gtattatgtt gtttcaataa ggattacgag taagataaaa aagctcactc
   129781 aatttcaagt aaaggagtga agccttatgc ctaaaaataa aaatgaaaca ttgtgtgtag
   129841 aagatttaag acacgctgaa tattacgaaa tgcaaaacac ctttgatgat ttatatgcca
   129901 aaagtaagaa tggagatatt ttcactcatc ttatggatat tatcctatcg agagaaaata
   129961 tattactggc atatcgaaat atcaaagcaa atgcaggcag taaaacagca ggaacagacg
   130021 gtacaataat taaagatatt ggcaaattgc cagcagaaac agttgtcaaa aaagtaagat
   130081 acattgttgc aggcagtcca catgggtatc gacctaagcc agtgaggcga aaagaaatac
   130141 caaaaccaaa tggtaaaacc agacctctag gtattccttg tatgtgggac aggcttatac
   130201 aacaatgtat aaaacaagta ttagaaccaa tctgcgaagc taaatttagt gaaaacagct
   130261 atggttttag acctaatagg tcagttgaaa atgcaataaa agcaacctat aaccgcctac
   130321 aaatcagcca gctacattat gtgattgaat ttgatattaa gggtttcttt gacaacgtga
   130381 accattccaa gctgataaaa cagatatggg ctatgggaat acgggacaag cacttgatat
   130441 tcattttaaa aaggatatta aaagctccaa tcaaaatgac taacggtaca ataacatatc
   130501 cagagaaagg aactccgcaa gggggaataa tatccccact actagcaaac attgttctta
   130561 atgagttaga ccattgggta gaaagccaat ggcaggaaaa tcctgttaca aaaaactatg
   130621 tggttcatat caataaaagc ggtagcccat gtaaaagcaa cgcttacaaa gaaatgaaga
   130681 aaacaaagtt aaaggaaatg tatatggttc gttatgcaga tgattttaga gttttctgcc
   130741 gctacaagga aagtgctgaa aaagccaaaa tagcaatcac tcaatggatt gaacaacgat
   130801 taaaattgga agtatcacaa gaaaaaacaa gaattgtaaa tgttagaaaa agatactccg
   130861 actttcttgg tttcaagatt aaaatgatac cgagaagaaa gaagttagtt gttaaatcac
   130921 atataagtga taaacaattc aaaaaccaaa aagacaagct ggtatcacag gcaaagaaaa
   130981 ttgcttctcc ctcaaaaggg aaaacggaat tagaagaaac aagactttat aattcaatgg
   131041 tattaggtat gcaaaattat tatcagattg caacgaatgt aaatctggat tgtatgaaac
   131101 tgaatagagc tgtaatggct atcttcacta acagattagg tacaaacaaa aggggcagat
   131161 tgagaaaaac aggcagacaa cttacgacaa aggaggcaac aagatatggt aaatctaaaa
   131221 tgcttcggta tgttgctggc gagggcgaac ctattttccc tgttggatat atccaacaca
   131281 gaaaaccaat ggcaaaggtg tatttagcga attgctacac tctagaggga agaaaattta
   131341 tccacaccaa tctaagtgtt gataaattac tgatgtacca gttaatgaaa ttatctttgg
   131401 aaaatcgcac aatagaatac gcagacaatc gaatttcgct attttctgct caacatggaa
   131461 aatgtgctat aactctggaa gaatttcaac aagctaatga aatacattgt catcatattg
   131521 taccaactgg agctggtgga aatgacgatt ataaaaatct tattttggta aaagaggcgg
   131581 tacaccgtct aatacacgct aaaacagaag aaacaataca aaaatatata gctctattga
   131641 agctaaataa agtccagctc ataagactaa ataaatatag agtattagct ggcaatcaag
   131701 aattaaactt gatataggtc tactacataa atacttttca atataaacac gatggaacgc
   131761 ggagtgcggt gaaagtcgca cgctccgtgt gaatgggggg aaaagtttga gatatttata
   131821 atatcaggaa cttacctatc catatatcaa tggtttttaa ccaatgccca atccttagtc
   131881 ttactggcaa ttgtggtcat tggtttgttt ttaggattta agcgggagtt ttccaaactg
   131941 attggctttt tggtgattgc tttgattgcg gtcggattgg tctttaatgc ttctggggtg
   132001 aaggatgtct tactcagttt gtttaaccga attgtcggtg cgtaaggggg aagcacgatg
   132061 gaacagatgc gtgtttatat tgcgaacctc gggaaatata acgaaggtga attggtgggg
   132121 gcgtggttta ccccacctgt cgattttgat gaagtgaaag aacgaattgg gttaaatgac
   132181 gaatacgagg aatatgcaat tcatgattat gaacttccct ttgagattga tgagtatacg
   132241 ccaattgagg aaattaatcg gttgtgtggc ttagcggagg aacttgaagg aacgccagtt
   132301 ggtgaagttg cttctgagat tcaacatgct ttcttcaatt cttttgagga gatggtagag
   132361 catgtggatg atattatcta ttatccagat tgcgatgata tgagtgatgt agcatatttc
   132421 ttgattgtag aagctggtga ttttggagaa gtaccagaac acttgaagac gtatattgat
   132481 tttgatgcgt gtggtagaga cttggagatt ggaggcaatt atttggtaac gagtcgaggt
   132541 gtttttgagt atccatatta acaaaattat tgaagggtag ttgatttcta aactatcctt
   132601 ctttttaaag gaatgatttg atgaagaaaa taaaaagcta caccagtatt tgggcagttg
   132661 aaaaggtcat ttatgcaatt aatgactttc aactgccttt tcctgtgact tttaaccaga
   132721 tggcttggtt tgttttatcc ttgctgtttg tcatcgtatt tgcccatgtg cctccactat
   132781 ctatgataga gggggccttt ttaaaatact taggtatacc ggtggcagtt acttggttca
   132841 tgtcgcaaaa aacgtttgac ggtaagaaac cattgggatt tttacgatct tttattagct
   132901 atcacttacg atttaaggtc actttcgcag gaaagaaagt caaagaacag aagaaacgat
   132961 gggacgaacc cattactctg gtaaggagtg tgaactatgt acccgattaa gtatattgaa
   133021 aataatcttg tctttaatca agagggagaa tgttttgcct actatgagtt aataccttac
   133081 aattactcct ttttgtcacc tgaacagaaa tatcaagtcc acgataactt tcgtcaattg
   133141 attgcgcaaa atcgtgaagg caagattcat gccttacaaa ttgccacaga aagtagtatt
   133201 cgtgccacgc aagaacgatc aaaaaaggaa attaccgggc gattaacaga agtagcgaaa
   133261 caacgaattg atttacagac agaggcatta gtatccatga ttggcgatag tcagattgat
   133321 tatcgctttt ttattggctt caaactgatt gcgacagatg aagaggtcaa tctaaagaat
   133381 ctcaagaaat ctttcttctc cggctttcaa gaatttgtct atggagtgaa tcatcatttg
   133441 atgggcgatt ttgtttcctt atccaatgaa gaaattcgcc gatataccaa gcttgaaaaa
   133501 ctaatggaaa gtaaattggc tcgaagattt aaagtcagac gagtcacacc gagtgatctg
   133561 atgtatttga ttgaacatat ctatggcgaa aagggtacac catttgaaga atatgaattt
   133621 cagctaccaa agaaaaagct gaagtcggaa actttggtga aacgttacga cttattacgt
   133681 cccagtcgtt gtttgattga agaaaagccc cggtacttat gcatggaaca tgagaatcat
   133741 gaatcatatg tagcgtactt aacaattaat acaattgtgg gggaaatgga gtttccctcc
   133801 tcagaacttt tctattacca gcaacaacaa tttacattcc caattgacac tagtatgaat
   133861 gtggagattg tgacgaacaa aaaggcactt gctaccgttc gcaataagaa aaaggaatta
   133921 aaagacttgg acaaccatgc ctatcaatct gacaatgaaa caaattccaa tgtcttagat
   133981 gcattggatt ccgtagatga attggaaact accttggatc agtccaaaga atccatgtac
   134041 aaactgagct atgtggttcg agtaagtgcc gaatcagtag atgaactaaa gcgccggtgt
   134101 gatgaagtgc tagattttta tgatgatacc aatgtaaaac tagtccggcc ttttggcgat
   134161 atgatggggc tacatgaaga attcttacct tctagtaagc gatacatgaa tgattatatc
   134221 cagtatgtta cgtctgattt tctcgccgga cttggttttg gcgccactca gatgttaggg
   134281 gagttggaag gcatttactt tggttataac gtagatacgg ggcgcaatgt ttacctgaaa
   134341 ccggcattgg cctcacaagg ggtcaaggat tcagttacca atgcgctagc agcggcattc
   134401 ctcggttcac tcggtggcgg aaagtccttt agtaacaatc tcttagttta ttacgccgtc
   134461 ctttttggtg gacaagctgt gattgtcgat ccaaaagggg aacggggtgg ctggaaagaa
   134521 accttgccag aaattgcgga tgaaatcaat attctcaact taactagtaa gccaaaaaat
   134581 caaggattac ttgatcctta tgtgattatg gagaaaaaga aggattctga aagtctagca
   134641 attgatattc tgaccttttt aacaggaatt tctagtcgag atggggagaa gtttccagtg
   134701 ttgcgtaagg ccattcggac ggttacccaa agcaatcaac ggggattatt acaagtaatt
   134761 aatgagcttc gaaaagaagg ctcaccagtt gcggaaaata tcgcggatca catcgagtcc
   134821 tttaccgatt atgattttgc ccatttgctt ttctcagatg gttcgattac ccagtcgatt
   134881 agtttagata ggcagttaaa tatcattcaa gtagcggatt tggttttacc agatgcagaa
   134941 accacttttg aagaatatac caccatggaa ttgcttagtg tttccatgct aatcgtcatt
   135001 tccacttttg ccttggactt tatccatagt aatcgagaaa tcttcaaaat tgtagactta
   135061 gatgaggcgt ggagttttct tcaagtagcg caagggaaaa cattatcgaa taagctcgtt
   135121 cgtgctgggc gggctatgaa tgccggggtt tactttgtca cgcaaaatag tgatgattta
   135181 ctggatgaac gcttgaagaa taatatcggg ttgaagtttg cgtttcgcag taccgatatt
   135241 catgaaatca agaaaacctt ggaattcttt ggcttggatc gagaagatga aagcaatcaa
   135301 aaacgcctac gagatttgga aaatggccaa tgcttgatgc aggatttgta tggtcgggta
   135361 ggcgtggttc aggtacatcc agtctttgaa gaactcttcc atgcctttga tacccgtcca
   135421 cctgttcaag agagaatgga gtgaggggat gaaaaagaaa ctttttcgga ttgtgggaat
   135481 cgtttttatt agcatactca ctctgatagt tctattgagt ttagttggta cggtagccga
   135541 ggcgacaggg ctagttgatg atacagttga agcaggaaat ctatattcca aatattcact
   135601 gaacaactat caactagatt tctttgtgga tagctcttgg gattggttgc cttggaattg
   135661 gggtgatggc ttagggaaaa gcgtgatgta tggtctttat gccattacta atttcatttg
   135721 gacggtgagt ttgtatttgt cgaacgccac gggttatgtg gttcaagagg cttacaaatt
   135781 agatttcatt tcggatacgg ctgaaagtat tggaaagaat atccaaacat tggctggtat
   135841 tactgaaaat ggactccaga cctccggatt ttattttggg tttctattat tgatgatttt
   135901 agctctgggg gtgtatgtgg cgtataccgg attattaaaa cgagaaacca cgaaagcagt
   135961 tcgagccgtg attaattttg tgatgatttt tctactatcg ggttcgttca ttgcttatgc
   136021 gcctacctat atcacaaaaa tcaatgactt tagctcagat gttagtgaag cggcccttac
   136081 ccttggaacc gagatcgttg tacccaattc agaaagccaa ggaaaagata gtgtggattt
   136141 gattcgggat agtttgtttt cgattcaagt ccaacaacct tggttactac tgcaatttga
   136201 tgattccaac atagaagaaa ttggtgaaga ccgggtcaac aagattctat ctgtgagtcc
   136261 agatgaaaac aaaggcaaag atcgggaaga agcggtcaag gcagagattg aagacaatga
   136321 caatgcgaat ctcagtatta ccaagaccat gaaccgttta gggaccgtgg tctttttggt
   136381 attgttcaat attggcattt ccttctttgt ttttcttcta acagggatta tgttgttctc
   136441 gcaaattctc ttcattatct ttgcgatgtt tctgccaatt agtttcttat tgtccatgtt
   136501 gccgacttat gaaagtttag gaaagaaggc gattattcgt ttattcaata cgattatgat
   136561 gcgagcgggt gttactttgg tgattacgac tgcatttagc atctccacga tgtttttcaa
   136621 tatttcggca acctatccat ttttcatggt tgcttttctg caaattgtga cctttgccgg
   136681 tatctatttc aaattgggcg acattatgag tatgttcaac ctccagagta atgatagcca
   136741 gtcaatggga agacgcgtca tgcgaaaacc gcaaatgtta atgaatcgaa aattgcggca
   136801 actcaatcga aatgtgggac gagctttggc ttttggtggt ggtgcagcag tcggaaataa
   136861 gttggcaaag gaacaatcaa aatccaaatt taagccatcc ggttcttctc tacgaaagaa
   136921 ttcacgatta ccgaacgatc acgaaatact atctgactta actaaggaga atccagtttc
   136981 aaataataag aaacaatccc gaatgaattt ggctgggaga aaaatcggca aagttttgga
   137041 tacccaagct ttggtgaaag ataagactaa acaagtaaag gatcaggtaa ggaatacgcc
   137101 aacgaatttg aaatacaatc tccataaagg aatcgaaaag tcgaaaaaag caccagaaga
   137161 attcaagcgc ggactgttcc aagaaaaagc ggatcgagtg gatttgcgag aaaaacaacg
   137221 acaacgaaga aatgcgaaaa tggacgaaaa acgcaagata ctgagtgaag caacaaatcg
   137281 tcagggaaaa agaagggcga atattccaat agataaagca gctcaacctc agaaagatat
   137341 gatgctgaaa aaagaagcac caaagcggat tgtgagagca aatctgaatc ccgaaatcaa
   137401 acgaaaacta actagtcaag aaatcatttc aaaagggaaa agccaatcag caagtaagaa
   137461 aaattctttc caacaagtga aacagaggtc cactctgcca aagcagacca atcaaaaagt
   137521 acaaaaaaga atgaaccatc gtccaaaatc aaggtcaggt gagaaaaaat gaacttgaag
   137581 aaagtgggtg ttatttcatt aacttttctg accatctctt ttatgggtat tttgatgtgt
   137641 gtgggtttgt tgtttggtga agacagtgag ggaaatggta gttctggcac ttctcctggc
   137701 ggaactagtg tctcagaaga agtattgaaa caccgtgcaa tggtggaaaa gtatgccaaa
   137761 gaatcggata taacagagta tattccaatt cttttggcga ttattcaagt ggaatctggt
   137821 ggcacaatgg aagacgttat gcaaagttct gagtcagccg gattaccacc taattcatta
   137881 agtaccgagg catccatcaa acaaggctgt ctctattttg cgtctttggt taagcgttcc
   137941 aaagaactag ggtgtgatca agatagtatt attcaggcct ataactatgg tggcgggtat
   138001 ctagatcatg tcgggaaaaa cgggaagaag catagttttg ctttagctga atctttttca
   138061 aaggaaaaat caggtggtca aaaagtcgat taccccaacc caatcgcgat taaggaaaat
   138121 ggtgggtggc ggtataatta tggcaatatg ttttactgtt tattagtgaa gcaataccta
   138181 actacaactc agtttgatga caaaatagtc caagaaattt ttgatgaggc atttaagtat
   138241 gaaggaacgg cctatgtgtt tggtggctca agtccagaaa cggggtttga ttgtagtggc
   138301 ttgacccaat ggtgttatgc caaagttgac ctgaaacttc ctcgggtggc tcaggatcaa
   138361 tatgatgcca tgactcatat tgatctaaaa gatgccaaac caggtgattt agttttcttt
   138421 cattcaacct atgatgccgg tacttatgtg acccatgtgg gcatttacgc aggggagaat
   138481 cgcatgtttc atgcaggaga tccagtgggg tggacgaatc taacggaaaa ctattggcgg
   138541 cagcatctta tcggagctgg ccgatacaaa taagagaaaa gaggaaaaag aatgaagata
   138601 aaaattgaac ggaatcaaaa ggaaaagagc ccaaaaaaga aaaaagaacg agttgtatcc
   138661 gtgggtaagc atcgaaaaat ggtgcttgcc ctttggcttt tattgtcttg tagtcttgct
   138721 tttggcgttt ataaaaattt caccgccatt gatcaacata caactcatga aaaagtggtt
   138781 ataaaagaga aggtagtgaa tacttctggc gttgaaagtt ttacagagga ttttgcgaaa
   138841 gaatattttt catggaaaaa taacaaagaa gcaattgaaa agagaatgag taatctcgaa
   138901 cagtacctta cagaaaacgg tctcgcttta atccaagata tggttcgagc agatattccc
   138961 acgagttccg aagttcaatc tgtaaaaatt ctagatgttg aaaaacactc ggaagaattt
   139021 gtcgtttcat ttttagtgga gcaacatatt acagagggaa aaaagacgca atcaatttct
   139081 tctgcatatc gagtgacaat ctttgaagat gaaaacagga atcatttagt aactagtttg
   139141 ccaacaatga ttggaaagcc agacaaggca aaatatgaag caaaacaagt agaaaacgat
   139201 tcagaaattg atgccaaaac aacggaagaa atcaccgatt ttttagaaac attttttaaa
   139261 ctttatccat cagcttctga aaaagaattg gagtattatg ttgaaaatgg tgcgatgcga
   139321 ccaatcaata ttgacttaaa gttttcggag ttagagaatc cagtttatct acaaaacgga
   139381 aaaaattttc tagtgagtac aaagataaaa taccttgata atgtatcaaa aaccactagc
   139441 tactttcagt acaaattagt attacaaaaa aatggaaact ggaaaatcgt tgatgttaaa
   139501 taataatgac tcaatctaat tttattagaa gttataagta gtgtaactta tttcaggcag
   139561 aagtcgccca tcctctatag gtgggtgatg aatgccattc ggtaactcga aaaccgacaa
   139621 ttaagacata gtgccttttt attttaatcc atgtcataat cagtctatat aggaaatggt
   139681 tgatatacca tggaattaga tacaaataat cattcagttt ttcttcttgg ttaccccctt
   139741 attttagtag tgaaacattg taaacatgtc attgatgatg taatgtcagc ttatgcaaaa
   139801 actgcctttg aaagaatttc agaatcacat cacattacct tagatgaatg aaatcgtgat
   139861 aaagaatact ttcatattat gctcaaagca caacctaaaa ccgaattaac aaaattcagc
   139921 aatgcctaag ctcacgtctg ataaaatgag actttctaag ggtcaaaaat ttcctttgaa
   139981 tacgattatt gcttagataa aagtaaaagc cttagaacta cggggatagc ttggttaata
   140041 agagatatcg ttgttagtaa agacataggc ttgcaagtat gctctattcc caagaatctc
   140101 ccccttcaag caccaaggat cgttaaattc agctaagtgg caagtaattc actagacgat
   140161 aattatctcc atatttcaat ctcagctttt ccatttttca tagcaaattc cgttattttt
   140221 atagcatcta aaagattcag cttttccact gatctttcac cacttttcag cttttttatt
   140281 gtgcttaaat tgataccagt accttttgat attgaattgg aagtaaaatc attaagggtt
   140341 ttttttatta aattcatatc cgcaattcca gcgttcataa gaatgaagat tctcctctca
   140401 tagactactt tgaaaatggt actacagtgg ctgtttatat atttcagtag gttactgtag
   140461 tggtcatctt attataatta gaaaaggaac ctaaatcaaa aatgctaaag aaaattttca
   140521 tagtattaag cctctcatga ctaaagccac ggaattcttg ataaaagagt atacttgcaa
   140581 gcctaaacag cggtatctct tattaaccaa gctatccccg ttgttcctaa ggttcttgat
   140641 gttttctaag gcaatgcttg tattcatagc ccttggtcaa aatattgata ctatcgttga
   140701 cgtttcgatt atgatgtata cggcaaatag gacaagtcca ttctcgaatt gtgagtgact
   140761 tcttaccatc tgtgtgtcta cattctgaac caatttgact agacggaaat catttatcta
   140821 tcttaatgat tttttgacag aagtatcgaa aatctttaca taatctgggt gatgtattct
   140881 tatgcagatg agagcgttgg ctccgtattc ataaccagta gcctctaaaa cgtagtccat
   140941 cggtgggata cctagcttgc ggttgccagc ggctttcgca gtcttcttgt gatcaaatca
   141001 agcatctcat tgagcactag tattttgaag ataatacttg agtttttcgg cttttagaag
   141061 ttcacttcat cttccatcat ccatggaaat cccactcacc catacgcagg cctccaaaaa
   141121 ttcttcaaca gtggtttttt cagacatttt tctgaatacc tccttgtttt ttgatacgcc
   141181 agatagtcag gaaaaaggca acaaaacaca aaacaaagct gcctaaaaag gtaatcttca
   141241 ttccatataa aaagacatcc ggccgatttg cgatatagtt agttacttgc tggcccatct
   141301 tagcagacat cgcttgatat aagaccgtcg tagaaagcga aatcccgctg accatcccca
   141361 aatttcgggc aaaggaattc atcgagcctg ccagtcccaa gttttcgata gtgaccgagc
   141421 tcataaccat cgtattattg ggggactgga acaaggcatt gccggcaccc atgatggcag
   141481 tagcgacaat gtatagccac aaaggagagt ccactgacaa aaacatatac atgacctggg
   141541 ttaccgacaa taagcccaag cctactaata ccaaaatctc cgggccaacc cggtcggtca
   141601 ggtagccgct taaaggcgcc ccgacgacca tcatcaaagg aaagaccatc atcaacagcc
   141661 cagcatagct aggactcaac ccgcgagcat tttgcagata aaaaggaatc actacattga
   141721 caaagaagtt ggaagaaaaa atcaacaagg ctgtaatcaa gctcatggta aaaatcttgt
   141781 tcttaaaaat accgaaagaa atcaatggag aggctgcttt cttttcaact tttaaaaagc
   141841 tgacaaaggc aatcactgaa attacgaaca gtacaagggg gactggatgg aaaaagccac
   141901 tttcttgccc caaaaagatt gctccaaaaa agctgataat cgtagccgca atggcagcaa
   141961 agccccctcc atcgattgta tggccgctca tggtgatatc ttttggtaag aatttttcag
   142021 caatcaacat cgttacgatt cccaccggta cattgatcca aaaaatgtac gcccaagaaa
   142081 attgggacaa aatcaagccg ccaagacctg gtccagcaat cgagcctaat gaaacaaacg
   142141 cacctattgc tcccaatgcc cgaccacgtt catgtatggg aaagacttcc gtgatgattc
   142201 cggcatttgt agccatagtc atactagcac caatggcttg taccacccgt gcgaacaata
   142261 aaatacctag cgaatgattg aacccacaca acagcgatcc caagacaaag atcagcgtac
   142321 caatccgaaa tactttgatt ttcccacggc tatcgccaat tttaccaaac agcaacaaac
   142381 aagaacagac aatcatcaga taaacggaca ctacccattc cgcttgattc attggtatgc
   142441 ccatatcatc tgagatggta ggtagtgcaa tattgacaat actgccatcc aatgtggaca
   142501 tgaaggtaaa catagatata gcaatcaaaa tccaccagcg atttttttgg acttttgcat
   142561 cttcttgata actatacata ataggatttc ctttctaatg atcgtgtagc taagaacaat
   142621 ataacctatg tctactgccc aacaacttct cgcgactcta gccataggaa gcttgagtaa
   142681 tttcgatttg atatcctcat gtaaccatgt aagttggaga tgctttattt gaacttactc
   142741 tatagtaact agtgataatt cgctttactt tcttctagca atttctaaaa gtcgacttca
   142801 ttgttcttca gattaatagt gtgagctatc tcgtgagacg taagcaaatt tccattctac
   142861 tttttcccaa ttttttcata tttatggtgt tgcacctatt tgttttccaa tttgcttttc
   142921 aaatacattg ctatgatatt caattccata ggattatact aaatatcaat agtatgaata
   142981 atatattata gatgtttata tatcactgtt aattattatc cacaataatt aatgattacc
   143041 tcgatatttg tcaatcaaag gttgaaacaa tttattttca gcatcttttc tagcttgagc
   143101 tgcactctta atagaatcat acgatcctaa atagtacctc ttttttttta aagttatata
   143161 cgcaatctat ttctctttag aacgataaac tcccttaaca ccacttgtat tatttttcgg
   143221 taattttgac gttagacact ctattactgt cccttcaaca catgtccttg tttcttgcct
   143281 ttttaaacat ccaaaacttt gagtatgtcc aaaaaataag ttactataac ttatctcaca
   143341 catactgcca cactcacaat gacaaaccca ttttgttttc catgaacagt tattgtccaa
   143401 aggatacttt gcagtaagta atccgaattt tttattttca atgtgatgct tttttgattt
   143461 caaacatcca cagcttttta catcaccttt tagaagtcgc tttgccgata ctaacttttt
   143521 tctcccacac agacattgac attcccaaac aacagttcct tcacttcgca gtttagttgg
   143581 cttgattgca actaacttac caaaagtttt atttgtcaaa tttttatatt tatgcctatt
   143641 tttataattt ccacatccac aacttttggt tctacctgat agtaagtttg atcgatatac
   143701 aatcgtttca ttcccacagt cacataggca acgatatttt ttatatccat tatgagtaat
   143761 ctcctcaaca acagtaaggt gaccatatct ttccttcact gcacctaccc tcccaagaaa
   143821 gaagtaccat ataatttcaa ttaactttta ataaatcaga aaaaaatatt tccaattttt
   143881 cttagtctga ttttatgact aatttacaat acaagactga acgatacgta cacgaaatcc
   143941 tcaagataga taaattgttt tcatctagtg aaacctgctc aaaatatgag cataaagacg
   144001 gcaataatac actcgatatt cgataatgga cttgttttat ttgtcaaacc catcgtaatc
   144061 gagatatcaa ttccagtctc aatatcctga tcaaaggtct aagaatccaa ccattttctt
   144121 gttactttgt cagattgatt acctttttta gtctccgaat aataaggttt tcggatcaac
   144181 taacatgctc tgagaaagac tactatcttt gcaaatttcc aaatgaaggt gtgggccagt
   144241 actattccca gtacttccta catagccaat tatttgtcct tgcaaaacat tatctccagt
   144301 ttttactagg tattgttgct ggtgagcata taacgcggtt gatccatctt cgtgttgtat
   144361 caccacgtaa tttccccaag agtagtgaaa ctctgcttta acaaccttac cagctttaac
   144421 tgcatgaatc ggctcaccct gtgtagctgc catatcaagt cctcggtgaa attcatttcc
   144481 acgatttcca aacaaactgg ttattgaata attatgaata ggcacttggt atccagtctt
   144541 actcatttgt ggacctttaa cttctttatc atagttggtt aaatcgtagg ttttaattaa
   144601 ttcatttagc ttcaaatagt attgtgtatc tgttgcatac cgtcctgtaa ggaatttagt
   144661 tgcttctcga tatgttttac tattagcttt taatgctcct gcataaaaat ctttatttcc
   144721 actaattccc ttagttaata atttggcata atcttcaaag ctttcctcat agttttcata
   144781 cactctaaat tttgattggg tcgtataaag cgttccatta cccaaatctt cgtttgttac
   144841 cataatgaca aagtttccat tataagttcc ttttatccca aataaattgt aattcggtgc
   144901 ctgagctaac tggctttgac cactggcaga ttctaagatc gcttgtgcaa tcataacaga
   144961 agcatataaa tcatatttct gaccaatttt tctcgcagac tcaccaattt tcataataaa
   145021 attttctaca gattcatttt tgtcaaaatg aatttcttca ttaccagata gtattggttg
   145081 tgattggaaa gattctgttg attctatttg ctgtggtgtc gaaaaagttt ttgtttgtcc
   145141 ttccgttttt ggcgcttcct tttttgaaga ttctatatgg tttggttttg tcactttcga
   145201 agaagttatt tcacttgtac tacttgaagt tgttgaagat tcggtacttg aaatcgtact
   145261 actttcactt gacgaagttg ttgaagactc ggcatttgaa gtcgtactac tttcacttga
   145321 tgaagttgtt gaagactcgg catttgaagt cgtactactt tcacttgatg aagttgttga
   145381 agactcggca tttgaagtcg tactactttc acttgatgaa gttgtcaaaa gttcactact
   145441 ctctgctgtt acatcggaat tactcatttc agtcgtctcg gttctttctt ttgcaatttt
   145501 gtatgttgaa ttttcgcttg ccaacacatg gaaaggtgtt gctataagga gttgggacat
   145561 taatataact gctgatgcaa gttttaaaga ttttttcatt tgatttacct ctcttttttc
   145621 tctttaatag tgttttctat taaaaattat gataaatatt ttcaatgaat tgagtaatac
   145681 agtatatttc ttgatttcat ttagtaacga ttatgtttca atgtttaatc ctgttactgc
   145741 ctttaaaata aaattatagg gttggctaaa actaggatga aataaataat ctaacatttt
   145801 caatttgtct aatgtaattt gttcttctat agcaagagaa aacattgata atagtccaga
   145861 taaatcttct tgactacaaa gttgtacacc tactattctc tttgtatttt tttcaaagct
   145921 aattcttaat tttacacgac tattttttct caaaaaagca ggtctaatga aatcttctat
   145981 ttctatataa tctatagact cacttaataa tcgtgctgtt tttaaattca aacctgctgc
   146041 gtaaaaattg taattaaata tagaaaagcc atttgtaaat tgggaaccag aaggtgtaaa
   146101 atcttgattg ttaatatgtt gagttgcaat ataagctgtt cttagagcat tagaaataga
   146161 aaaatcaaca ctacttctat taatggacgt aaaaaaagtt gtagcacaat ccccaatagc
   146221 atatatatct tttatatttg tttgctggta ttcattagtt agatatgctc cactaacatc
   146281 tctcaagagt tccttttccc caattggact attagataga aatcctatag cttgtacgac
   146341 catatccata gagtattggg taccacttgt agtgactatt ttttcaatct tttttcttcc
   146401 taaatatttt ttaggacttt ctgatagaca aagatgtatt ccattttttg atagtatttc
   146461 ttcaacttta tctgaaaaac tacggtcgta ataagtcgac aacactctat ctgcaacatc
   146521 gaaaagatat acttctttcc ctctttttct tatggcttca gcaatttcaa ctccaatata
   146581 tcctgctcca ataattccta cttttttaat agtactatca tccaaagctt taaaaatctc
   146641 ttttgcattt ggaaaattct ttatcgaaaa aatattagct aaattattcc ccggtatatc
   146701 tagcataatt tgctttgaac ctgtagctaa tataactttg tcatattctt gagagaatct
   146761 tgtaccatct ttttttacac aactaatctt tttattttga atatcaattt tgtcaacttc
   146821 tgtctctaga aataactttt ttatctcaga atttagtgtc attctatttt gataaaaaag
   146881 atcttctaaa ttacttactt ctccttttat aaataacgat gtcccacatt ccaagtaact
   146941 aatttctgat tttttatcga ttagaataac ttcataattt gaatcgctta agtttagaaa
   147001 tcgagctgcg gctagccctg aatggtttga accaataatt actatttttt ccacttaatt
   147061 acattctttt cctttctata aaaagtatat tcatctttaa ctaacactta tttcccatca
   147121 taaaaaagca aaaagaggaa gaaaaagatt cttcctcttc tcagagaaga cttaagaaat
   147181 tgattttcta ttcattctct ttttttcgat ttttataccc taataatcct aacgttccta
   147241 acagtattaa accaccgcta atagtaaaga tattactgtc actctctccc gtcttaggaa
   147301 aaacttttga ggactggctt ttgcctctat ttttgtcttg attgctgttg ctaccttgat
   147361 tgtcagtctt actaccttta ctaccgtttt ttccactgtc ttttttgttg gaagaaacaa
   147421 ctacattagt aggttcacta gtattaccag attcatcagt tgcagttact atcacttttg
   147481 tccctgcctc taatttagga actttaactg taaaattacc atttttatca gctgtcccat
   147541 ggtgttgact tccgtctggt aatgtaactg tcacctctgc atttggttca gttttaccag
   147601 taacaatttg gtcaccctct gtaataggat caacttgagg tttattcggt gcttttttat
   147661 ctactacaga aatagtaact tctacttctt ctttagatcc atctggatat gttactacta
   147721 cagtaccttt tttgtttcca gctgtactaa catctacttt ttctttccaa gtataagtag
   147781 ttccttttgg tagatcttct ttgttcttaa ttccctcaga tgcatctggc tctttattta
   147841 agtctgtagt cactttttgt ccttcaggat tatatttatc tgcatcggaa cgagtatctg
   147901 tcactgtaac gtctacttca acttcatcag atgatccatc tggatatgtc actacaatag
   147961 tacctttttt atttccagct gtgctaacat ctactttctc tttccaagca taagtagttc
   148021 cttttggtaa atcttctttg ttcttaattc cctcagatgc atctggctct ttatttaagt
   148081 ctgtagtcac tttttgtcct tcaggattgt atttatctgc attagaacga ttgtctgtca
   148141 cttctactgg aactttcacc gtatctttcg taccgtctgg atacgttact tcaatgacac
   148201 cttcataatt gcctggtgtg ttggtatcaa ttgtaccgcc gggagtaaca tctgttactg
   148261 ttgttccttc tggtaacgct ggcaagttag taacattatc tgttaaatct actgcgcctc
   148321 caatttctac tttttcgcct tctactgttg gttcatattt atcggcgtca gaacgattgt
   148381 ctgtcacttc tactggaact ttcaccgtat ctttcgtacc gtctggatac gttacttcaa
   148441 tgacaccttc gtaattacct ggtgtgttgg tatcaattgt accgccggga gtaacatctg
   148501 ttactgttgt tccttctggt aacgctggca agttagtaac attatctgtt agatctactg
   148561 tgcccccaac ttctactttt tcgccttcta ctgttggtt
//
LOCUS       DBBGSZ010000002       123895 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.002, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000002 DBBGSZ010000000
VERSION     DBBGSZ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 123895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 123895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..123895
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.002"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(59..187)
                     /locus_tag="ACIZE5_000136"
     CDS             complement(59..187)
                     /locus_tag="ACIZE5_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HGC6107324.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="ACIZE5_000137"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="ACIZE5_000137"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGC6107325.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="ACIZE5_000138"
     CDS             complement(1674..2729)
                     /locus_tag="ACIZE5_000138"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HGC6107326.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="ACIZE5_000139"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="ACIZE5_000139"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HGC6107327.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="ACIZE5_000140"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="ACIZE5_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HGC6107328.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="ACIZE5_000141"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="ACIZE5_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HGC6107329.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="ACIZE5_000142"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="ACIZE5_000142"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HGC6107330.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="ACIZE5_000143"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="ACIZE5_000143"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HGC6107331.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="ACIZE5_000144"
     CDS             10491..12050
                     /locus_tag="ACIZE5_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HGC6107332.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="ACIZE5_000145"
     CDS             complement(12161..14092)
                     /locus_tag="ACIZE5_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGC6107333.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="ACIZE5_000146"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="ACIZE5_000146"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HGC6107334.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="ACIZE5_000147"
     CDS             complement(15021..15773)
                     /locus_tag="ACIZE5_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGC6107335.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="ACIZE5_000148"
     CDS             complement(15932..16141)
                     /locus_tag="ACIZE5_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107336.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="ACIZE5_000149"
     CDS             complement(16152..17480)
                     /locus_tag="ACIZE5_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107337.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     NQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            17616..17771
                     /locus_tag="ACIZE5_000150"
     CDS             17616..17771
                     /locus_tag="ACIZE5_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HGC6107338.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(17845..18432)
                     /gene="yihA"
                     /locus_tag="ACIZE5_000151"
     CDS             complement(17845..18432)
                     /gene="yihA"
                     /locus_tag="ACIZE5_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HGC6107339.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="ACIZE5_000152"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="ACIZE5_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HGC6107340.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /gene="tig"
                     /locus_tag="ACIZE5_000153"
     CDS             complement(20012..21301)
                     /gene="tig"
                     /locus_tag="ACIZE5_000153"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HGC6107341.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="ACIZE5_000154"
     CDS             complement(21455..22387)
                     /locus_tag="ACIZE5_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107342.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="ACIZE5_000155"
     CDS             complement(22544..23203)
                     /locus_tag="ACIZE5_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HGC6107343.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="ACIZE5_000156"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="ACIZE5_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HGC6107344.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="ACIZE5_000157"
     CDS             complement(24244..24534)
                     /locus_tag="ACIZE5_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107345.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="ACIZE5_000158"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="ACIZE5_000158"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HGC6107346.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /gene="glmM"
                     /locus_tag="ACIZE5_000159"
     CDS             complement(26821..28176)
                     /gene="glmM"
                     /locus_tag="ACIZE5_000159"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HGC6107347.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="ACIZE5_000160"
     CDS             complement(28200..29369)
                     /locus_tag="ACIZE5_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HGC6107348.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /gene="cdaA"
                     /locus_tag="ACIZE5_000161"
     CDS             complement(29366..30253)
                     /gene="cdaA"
                     /locus_tag="ACIZE5_000161"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HGC6107349.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="ACIZE5_000162"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="ACIZE5_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HGC6107350.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="ACIZE5_000163"
     CDS             34320..34841
                     /locus_tag="ACIZE5_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HGC6107351.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="ACIZE5_000164"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="ACIZE5_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="ACIZE5_000165"
     CDS             complement(36284..36940)
                     /locus_tag="ACIZE5_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107352.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="ACIZE5_000166"
     CDS             complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="ACIZE5_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HGC6107353.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38477..39475)
                     /gene="yvcK"
                     /locus_tag="ACIZE5_000167"
     CDS             complement(38477..39475)
                     /gene="yvcK"
                     /locus_tag="ACIZE5_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HGC6107354.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="ACIZE5_000168"
     CDS             complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="ACIZE5_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HGC6107355.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40491..41222)
                     /locus_tag="ACIZE5_000169"
     CDS             complement(40491..41222)
                     /locus_tag="ACIZE5_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HGC6107356.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41226..42491)
                     /locus_tag="ACIZE5_000170"
     CDS             complement(41226..42491)
                     /locus_tag="ACIZE5_000170"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HGC6107357.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="ACIZE5_000171"
     CDS             complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="ACIZE5_000171"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HGC6107358.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="ACIZE5_000172"
     CDS             complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="ACIZE5_000172"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HGC6107359.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47833..49335
                     /locus_tag="ACIZE5_000173"
     CDS             47833..49335
                     /locus_tag="ACIZE5_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGC6107360.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49337..50074
                     /locus_tag="ACIZE5_000174"
     CDS             49337..50074
                     /locus_tag="ACIZE5_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGC6107361.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="ACIZE5_000175"
     CDS             complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="ACIZE5_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HGC6107362.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="ACIZE5_000176"
     CDS             complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="ACIZE5_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HGC6107363.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="ACIZE5_000177"
     CDS             complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="ACIZE5_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HGC6107364.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="ACIZE5_000178"
     CDS             complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="ACIZE5_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HGC6107365.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(55573..56739)
                     /gene="hemW"
                     /locus_tag="ACIZE5_000179"
     CDS             complement(55573..56739)
                     /gene="hemW"
                     /locus_tag="ACIZE5_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HGC6107366.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNAHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(56755..56982)
                     /locus_tag="ACIZE5_000180"
     CDS             complement(56755..56982)
                     /locus_tag="ACIZE5_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HGC6107367.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            57466..58073
                     /locus_tag="ACIZE5_000181"
                     /pseudo
     CDS             57466..58073
                     /locus_tag="ACIZE5_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313657.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
     gene            58246..58959
                     /locus_tag="ACIZE5_000182"
     CDS             58246..58959
                     /locus_tag="ACIZE5_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107368.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(59074..60084)
                     /locus_tag="ACIZE5_000183"
     CDS             complement(59074..60084)
                     /locus_tag="ACIZE5_000183"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HGC6107369.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(60121..60603)
                     /locus_tag="ACIZE5_000184"
     CDS             complement(60121..60603)
                     /locus_tag="ACIZE5_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HGC6107370.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            60753..61121
                     /locus_tag="ACIZE5_000185"
     CDS             60753..61121
                     /locus_tag="ACIZE5_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HGC6107371.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            61586..62038
                     /locus_tag="ACIZE5_000186"
     CDS             61586..62038
                     /locus_tag="ACIZE5_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6107372.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(62162..63013)
                     /locus_tag="ACIZE5_000187"
     CDS             complement(62162..63013)
                     /locus_tag="ACIZE5_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HGC6107373.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(63026..63811)
                     /locus_tag="ACIZE5_000188"
     CDS             complement(63026..63811)
                     /locus_tag="ACIZE5_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HGC6107374.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            complement(64163..65104)
                     /gene="ribF"
                     /locus_tag="ACIZE5_000189"
     CDS             complement(64163..65104)
                     /gene="ribF"
                     /locus_tag="ACIZE5_000189"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006747 - FAD biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009398 - FMN biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HGC6107375.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            complement(65108..66031)
                     /gene="truB"
                     /locus_tag="ACIZE5_000190"
     CDS             complement(65108..66031)
                     /gene="truB"
                     /locus_tag="ACIZE5_000190"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HGC6107376.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            complement(66399..68761)
                     /locus_tag="ACIZE5_000191"
                     /pseudo
     CDS             complement(66399..68761)
                     /locus_tag="ACIZE5_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase"
     gene            68926..69382
                     /locus_tag="ACIZE5_000192"
                     /pseudo
     CDS             68926..69382
                     /locus_tag="ACIZE5_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035543.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            complement(69539..69886)
                     /gene="rbfA"
                     /locus_tag="ACIZE5_000193"
     CDS             complement(69539..69886)
                     /gene="rbfA"
                     /locus_tag="ACIZE5_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HGC6107377.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(69913..72219)
                     /gene="infB"
                     /locus_tag="ACIZE5_000194"
     CDS             complement(69913..72219)
                     /gene="infB"
                     /locus_tag="ACIZE5_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HGC6107378.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(72232..72543)
                     /locus_tag="ACIZE5_000195"
     CDS             complement(72232..72543)
                     /locus_tag="ACIZE5_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HGC6107379.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(72540..72833)
                     /locus_tag="ACIZE5_000196"
     CDS             complement(72540..72833)
                     /locus_tag="ACIZE5_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HGC6107380.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(72855..74030)
                     /gene="nusA"
                     /locus_tag="ACIZE5_000197"
     CDS             complement(72855..74030)
                     /gene="nusA"
                     /locus_tag="ACIZE5_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HGC6107381.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(74053..74526)
                     /gene="rimP"
                     /locus_tag="ACIZE5_000198"
     CDS             complement(74053..74526)
                     /gene="rimP"
                     /locus_tag="ACIZE5_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HGC6107382.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(74671..79029)
                     /locus_tag="ACIZE5_000199"
     CDS             complement(74671..79029)
                     /locus_tag="ACIZE5_000199"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HGC6107383.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            complement(79241..80950)
                     /locus_tag="ACIZE5_000200"
     CDS             complement(79241..80950)
                     /locus_tag="ACIZE5_000200"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HGC6107384.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            complement(81018..82286)
                     /gene="rseP"
                     /locus_tag="ACIZE5_000201"
     CDS             complement(81018..82286)
                     /gene="rseP"
                     /locus_tag="ACIZE5_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HGC6107385.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(82447..83247)
                     /locus_tag="ACIZE5_000202"
     CDS             complement(82447..83247)
                     /locus_tag="ACIZE5_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HGC6107386.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(83244..84056)
                     /locus_tag="ACIZE5_000203"
     CDS             complement(83244..84056)
                     /locus_tag="ACIZE5_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HGC6107387.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(84251..84808)
                     /gene="frr"
                     /locus_tag="ACIZE5_000204"
     CDS             complement(84251..84808)
                     /gene="frr"
                     /locus_tag="ACIZE5_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HGC6107388.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(84811..85533)
                     /gene="pyrH"
                     /locus_tag="ACIZE5_000205"
     CDS             complement(84811..85533)
                     /gene="pyrH"
                     /locus_tag="ACIZE5_000205"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HGC6107389.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(85669..86550)
                     /gene="tsf"
                     /locus_tag="ACIZE5_000206"
     CDS             complement(85669..86550)
                     /gene="tsf"
                     /locus_tag="ACIZE5_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HGC6107390.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(86649..87431)
                     /gene="rpsB"
                     /locus_tag="ACIZE5_000207"
     CDS             complement(86649..87431)
                     /gene="rpsB"
                     /locus_tag="ACIZE5_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HGC6107391.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            87790..88269
                     /locus_tag="ACIZE5_000208"
     CDS             87790..88269
                     /locus_tag="ACIZE5_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGC6107392.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            88486..89577
                     /gene="phnW"
                     /locus_tag="ACIZE5_000209"
     CDS             88486..89577
                     /gene="phnW"
                     /locus_tag="ACIZE5_000209"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HGC6107393.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            89570..89698
                     /locus_tag="ACIZE5_000210"
     CDS             89570..89698
                     /locus_tag="ACIZE5_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HGC6107394.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            89702..90247
                     /locus_tag="ACIZE5_000211"
     CDS             89702..90247
                     /locus_tag="ACIZE5_000211"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HGC6107395.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(90701..92392)
                     /gene="argS"
                     /locus_tag="ACIZE5_000212"
     CDS             complement(90701..92392)
                     /gene="argS"
                     /locus_tag="ACIZE5_000212"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HGC6107396.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(92812..93759)
                     /gene="arcC"
                     /locus_tag="ACIZE5_000213"
     CDS             complement(92812..93759)
                     /gene="arcC"
                     /locus_tag="ACIZE5_000213"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HGC6107397.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(93874..94893)
                     /gene="argF"
                     /locus_tag="ACIZE5_000214"
     CDS             complement(93874..94893)
                     /gene="argF"
                     /locus_tag="ACIZE5_000214"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HGC6107398.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(94984..96213)
                     /gene="arcA"
                     /locus_tag="ACIZE5_000215"
     CDS             complement(94984..96213)
                     /gene="arcA"
                     /locus_tag="ACIZE5_000215"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HGC6107399.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            96674..97375
                     /locus_tag="ACIZE5_000216"
     CDS             96674..97375
                     /locus_tag="ACIZE5_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HGC6107400.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(97984..99000)
                     /gene="tsaD"
                     /locus_tag="ACIZE5_000217"
     CDS             complement(97984..99000)
                     /gene="tsaD"
                     /locus_tag="ACIZE5_000217"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HGC6107401.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(98997..99461)
                     /gene="rimI"
                     /locus_tag="ACIZE5_000218"
     CDS             complement(98997..99461)
                     /gene="rimI"
                     /locus_tag="ACIZE5_000218"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HGC6107402.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(99468..100010)
                     /gene="rimI"
                     /locus_tag="ACIZE5_000219"
     CDS             complement(99468..100010)
                     /gene="rimI"
                     /locus_tag="ACIZE5_000219"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HGC6107403.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(99994..100716)
                     /gene="tsaB"
                     /locus_tag="ACIZE5_000220"
     CDS             complement(99994..100716)
                     /gene="tsaB"
                     /locus_tag="ACIZE5_000220"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HGC6107404.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(100907..101887)
                     /locus_tag="ACIZE5_000221"
     CDS             complement(100907..101887)
                     /locus_tag="ACIZE5_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6107405.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(101911..103395)
                     /gene="galT"
                     /locus_tag="ACIZE5_000222"
     CDS             complement(101911..103395)
                     /gene="galT"
                     /locus_tag="ACIZE5_000222"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGC6107406.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(103407..104396)
                     /gene="galE"
                     /locus_tag="ACIZE5_000223"
     CDS             complement(103407..104396)
                     /gene="galE"
                     /locus_tag="ACIZE5_000223"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGC6107407.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            104644..104811
                     /locus_tag="ACIZE5_000224"
     CDS             104644..104811
                     /locus_tag="ACIZE5_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HGC6107408.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(104873..106684)
                     /locus_tag="ACIZE5_000225"
     CDS             complement(104873..106684)
                     /locus_tag="ACIZE5_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HGC6107409.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(106681..107046)
                     /locus_tag="ACIZE5_000226"
     CDS             complement(106681..107046)
                     /locus_tag="ACIZE5_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HGC6107410.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(107209..107604)
                     /locus_tag="ACIZE5_000227"
     CDS             complement(107209..107604)
                     /locus_tag="ACIZE5_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGC6107411.1"
                     /translation="MVLWVINIILLLIVLAIIFWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(107622..108584)
                     /locus_tag="ACIZE5_000228"
     CDS             complement(107622..108584)
                     /locus_tag="ACIZE5_000228"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HGC6107412.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACANLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(108584..108796)
                     /locus_tag="ACIZE5_000229"
     CDS             complement(108584..108796)
                     /locus_tag="ACIZE5_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HGC6107413.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(108817..109515)
                     /locus_tag="ACIZE5_000230"
     CDS             complement(108817..109515)
                     /locus_tag="ACIZE5_000230"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HGC6107414.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(109535..110077)
                     /locus_tag="ACIZE5_000231"
     CDS             complement(109535..110077)
                     /locus_tag="ACIZE5_000231"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HGC6107415.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(110209..111213)
                     /locus_tag="ACIZE5_000232"
     CDS             complement(110209..111213)
                     /locus_tag="ACIZE5_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGC6107416.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIGLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(111210..112199)
                     /locus_tag="ACIZE5_000233"
     CDS             complement(111210..112199)
                     /locus_tag="ACIZE5_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGC6107417.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(112196..113002)
                     /locus_tag="ACIZE5_000234"
     CDS             complement(112196..113002)
                     /locus_tag="ACIZE5_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6107418.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKITLLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            113168..114124
                     /locus_tag="ACIZE5_000235"
     CDS             113168..114124
                     /locus_tag="ACIZE5_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6107419.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(114201..114719)
                     /locus_tag="ACIZE5_000236"
     CDS             complement(114201..114719)
                     /locus_tag="ACIZE5_000236"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0005542 - folic acid binding [Evidence
                     IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HGC6107420.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(114807..114956)
                     /gene="rpmG"
                     /locus_tag="ACIZE5_000237"
     CDS             complement(114807..114956)
                     /gene="rpmG"
                     /locus_tag="ACIZE5_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGC6107421.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            115184..115630
                     /locus_tag="ACIZE5_000238"
     CDS             115184..115630
                     /locus_tag="ACIZE5_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HGC6107422.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(115825..117720)
                     /gene="asnB"
                     /locus_tag="ACIZE5_000239"
     CDS             complement(115825..117720)
                     /gene="asnB"
                     /locus_tag="ACIZE5_000239"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HGC6107423.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKLDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(118045..119019)
                     /gene="bsh"
                     /locus_tag="ACIZE5_000240"
     CDS             complement(118045..119019)
                     /gene="bsh"
                     /locus_tag="ACIZE5_000240"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HGC6107424.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNINKEDLDRHELVSYPVIKEQQINYVN"
     gene            complement(119355..119442)
                     /locus_tag="ACIZE5_000241"
     tRNA            complement(119355..119442)
                     /locus_tag="ACIZE5_000241"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(119408..119410),aa:Ser,seq:cga)
     gene            complement(119587..120153)
                     /locus_tag="ACIZE5_000242"
     CDS             complement(119587..120153)
                     /locus_tag="ACIZE5_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6107425.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            120408..121739
                     /locus_tag="ACIZE5_000243"
     CDS             120408..121739
                     /locus_tag="ACIZE5_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HGC6107426.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            121705..122055
                     /locus_tag="ACIZE5_000244"
     CDS             121705..122055
                     /locus_tag="ACIZE5_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107427.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(122147..122566)
                     /locus_tag="ACIZE5_000245"
     CDS             complement(122147..122566)
                     /locus_tag="ACIZE5_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HGC6107428.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(122567..122911)
                     /locus_tag="ACIZE5_000246"
     CDS             complement(122567..122911)
                     /locus_tag="ACIZE5_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HGC6107429.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            123261..123857
                     /locus_tag="ACIZE5_000247"
     CDS             123261..123857
                     /locus_tag="ACIZE5_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HGC6107430.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT        34622 a        26400 c        21606 g        41267 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gattttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagac cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagccat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
    37021 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
    37081 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
    37141 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
    37201 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cagttataga
    37261 taaatacttg atcttatcta tatcaggact tctatattaa gcaaaaattt atgtacaaaa
    37321 ctaaaatctt cattcagttg tctccccgct ttttatacga ttgtattaaa aacaatagaa
    37381 gcctttccaa attatgttac tccagtaaag atggaattat agtttgacgg aagaaaagca
    37441 agtataactt ttaaaaaaaa ctgatacatt cgcatctcct gcttcatgta tcagtttttt
    37501 ctttggatta aactgcttct tcacgcagtt tttccgcaaa ttcatttatt ttgcgaattc
    37561 ggtgattaat tcccgatttt gatatcgcac ctgagggaat catttcccct aattctttca
    37621 agctgacctc tggatgttga agccgaagtt ctgcgatttc ctgaagtttt tcaggaaggg
    37681 catgtagacc gacctttgct tcgatcaatt cgatgttttc gatttgttta gaagccgcat
    37741 caatcgtctt gttcagattt gctgtctcac aattgactag acgattgacc gaatttctca
    37801 tatcccgtac gattcgaaca tcttcaaatc ggagcattga gttggttgca ccaatcaatg
    37861 ttaagaaatc agcaattttt tctgctcctt ttaaataaga aatatagcca ttgcgccgtt
    37921 caagcgttcg agcatgtaga ccgtaataat ttaacatatc gcaaatgtct tggttatgct
    37981 gttcataaat agaaaatatt tccaaatgat aacggctcgt ttccggatta ttgactgaac
    38041 ctgaggccat aaaagcacca cgtaagtaag aacgcatttt ttgcgaattt cccataatct
    38101 cgtccgaaac gtgtccattg aacatcatac catccatgat atcaagatcc atcaacacat
    38161 cttttgtgcc ttgcttcaac cggacgatat agacattgtt cttttttaat ttcatttttt
    38221 tacgaacgag tagctcactt cgtacctgat aatgatcttt caaaagagaa tagatacgtc
    38281 tggcaattgc agcattttct gtttggacgt tcaaaataaa ctgctggttc acaataccta
    38341 aagagccgtt cattcgcagc aaagcagcta attccgcttt cgcatgttct cgatgaactt
    38401 ccaaaccagt tagttctttc ttcacatctg cagcaaatga catcctattc tcctcctttc
    38461 tccaacaata aattgcttaa tattttgaac cgaaaactaa acggaacaat tcttctacta
    38521 ctttgtctcc atcgtggaag acaccaccat ctttcaattc caaaaagtcg gtggaaatca
    38581 ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc gacttgtact agatactcat
    38641 catagatctc tgggtccata taatcttcag gcactttttc cgtattgacc aatactgtat
    38701 cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat atgatcggca tctgtgaaat
    38761 gttccgtttc ccctttttgg gtcatgatat tacagatata gacggtttca gcagttgtct
    38821 tgagcattgc ttcgccgatt tctggtatca ctaaatttgg aaggatactg gtgaataaac
    38881 ttccgggtcc caaaacgacc atgtcggcgt ccataattgc tgaaacgact tttcgagccg
    38941 ctttggcttc acttttatca tttgtgttgc agacatacac acggtcaatg gttttacggt
    39001 cgatcgcgat tttagattct cctactgcag tcgttccgtc tttaaagaca gcatgcaagg
    39061 tcaaaggagt ttctgaagaa ggataaacat gtccatctac atgcatcatt tttgctaata
    39121 attgaatcgc ctcataagtg cttccccgca tctcggaaac tgcggcaatg atcagattac
    39181 cgatcgtatg attggctaaa aactgatctt cctttttgaa acggtattgg aaaatatctt
    39241 catagaattg tggcatatcc gataacgcca ctaagacatt tctcaagtca ccaggaggag
    39301 ccatagcgat cgattctctg attgcaccgc tgcttccccc atcatctgca acagtcacta
    39361 ctgctgtgat atctgctcct tgatttcgca aacttttcag gataactggc agaccagtgc
    39421 caccgccgac cactacgatc tttggttttc ttatccggta ggttttcatt ttcacgaccg
    39481 gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc acattgactt tatagttttt
    39541 ccctaaagca tttgccaaac gttcagtcaa tgccacagaa cggtgttgac cgcctgtaca
    39601 gccgattgca actgtcaagc tgctttttcc ttctttaatg tatccaggca atacagtttc
    39661 cagaagatcc aaaaatttat ggtagaatga ttgcgtttca tcaaaggaca tcacataatc
    39721 atagactggc tgatcttttc cggtcaatgg tcttagttcc gggatataat gagggttggg
    39781 caaaaaacgc acatccatca caatatccga atcgatcggc aacccgtatt taaaaccaaa
    39841 tgatacaaat tcgatccgaa atccttggtc tccctttgat ttgaatgact cattgatttt
    39901 ttcacgtaat tgtcgtggtg tcaatgtcgt cgtatcaatg atcacggaag cttgggcttt
    39961 caagtcgtct agtatcgccc gttctttacg tatcccttca gtgatcaaac cgtccatcgc
    40021 cattggatgt gctcgtcttg tttctttgta gcgagccact agttcttcgt ctgaagcatc
    40081 taaaaataag atagaagtgt cgatgaagtt cgtattttcg atttcgatca gcatgttttg
    40141 gatttcttca aagaaggaac gagaacgtaa atccactcct aaagccattt ttgtgacttt
    40201 gcctgattct ttgattaatt cccagaattt tggaatcaat cgaggcggca tattatcgat
    40261 acaaaaatag cccatatctt caaaactttg gatagctact gttttccctg caccgctcat
    40321 acctgttatg atgactaatt gcaaattatc tgtcataatt acgaactcct ctcacattgt
    40381 gcatagtaaa attatatcat tccgggcgta tcattaccag ttttcttttt cttttacaaa
    40441 aagatttgga ccaaatatct tttaggatat ttgccccaaa tccaattttt ttacttttcc
    40501 gatgctgtat ccaatgcctt gcttctttca gctagcgctc gttcaatcgt ccgatctgct
    40561 aaaatagatt gggcatcgat cactggataa tggttatctt cagcaaattc atgcatcaat
    40621 gacaattctg tgcaacctaa gataactttt tcacagttta ggcgctctac cgcttcttct
    40681 aagatttcgt aatatagctc ttgattcaaa taatccgatt ccttgatctc atgatagatc
    40741 agataattga ttttttcttg aagaacagta tcaggaatca ctgtttcgaa tccaagattt
    40801 ttgacttcgc gttcatagat tccagctttc atacttcctt ctgttcctag aatcgctact
    40861 ctccctgtcg tatgctgacg gacaagttca tttgctgctt ctcttggcat atgaaggata
    40921 ggaatatccg ttgccgcttg taattcttca aaaaagtagt gtgcggtgtt acaagtcaac
    40981 acaatgaagt tcggctgcaa taaattttgt ttctcaatat catccagcag aaacggcatt
    41041 ggattttctt ctgatcgatc taaaatataa gctgtacgat caggaactgt tgcatgattg
    41101 aataagacat aattcaaata ttcttgatct tttgtagctt tcgttcggtg gttgatcaag
    41161 cgaacaaaac tttctgtcgc catcgtgccc attccgccta aaatactgaa aaaattctcc
    41221 atgaactagc cttctttcac atgaaaatac tttttgaatc ttggaatata gttatggaac
    41281 atatatttca tcaacaacca gcgcttgatt gaccggtctt tttcataaaa cacagtagta
    41341 ccgtaacgat tttctttgat catttgctca gctagttttt tgtcttcatt ttcccgagca
    41401 tattctaaaa agattttttt gggcacaccc atccataatc ttgctttatc tgattgattc
    41461 gttccatagg tcgtttcaac aaagggtttg ttaaacactc gatcttctgt gacgaaacga
    41521 gccagattca agccgttcaa tgtcacaaag aaactgctac gaccttgtct caaattgatt
    41581 tcaaataatt tatattctcc atctctagga tcatacttca tatcgaaatt ggcaaagcct
    41641 gtatattcga ttttttccaa aaatgcctta atggtttgat agattttttc gttataatct
    41701 ggcatgatca caacgtaatt accaatcgat gctggtgtag gatcttctaa cagtggatga
    41761 ccaagacaca tcatccgaac ttgatgatct tcatctacat acgcatttag cacacgcata
    41821 ttactatcat cacccgggat aaaatcttgt acaatcattt cacttttata accggcttcg
    41881 tatatccggc ctaaaattaa atcgaactct tctctagtct ctaaaataaa agcttttttt
    41941 cttccttcaa attggacaga aagatactcc acactgtttg caggtttcaa agcaactggg
    42001 aattcaaaag gcaattcctg ttccaaatgt ccatttacta acatttcttc tctgacgatc
    42061 aatgttttag gatacggaag atcatattct tcacaaactt cataaaagct tactttattg
    42121 atcagtcttt caaataaaga ataatcaata tatggacaga taaaatattc tgacagctct
    42181 tgtttatgtt gggagatcaa ttctgcatat ccatcaccac aagcaatcaa aagatatttt
    42241 ttactcttat cagaatatct ttcttttgcc aaacgaagca tcgtctcgat aaacacaggg
    42301 tctttatcaa atcctggaat aacttctaca ttgacaattt tactgtagcg ggtaggggct
    42361 aactgatccg aagcatatgc ttggcagatt ttgccgtatg cttcattaaa agaacgtgcc
    42421 ataccataaa cgttcatgtc gcttcctaat aatataggga taaattcttc attttcaata
    42481 ctgttcatca ttatctctca cttactcata atctcttgtt tttcttttcc aactacacaa
    42541 ggaatatcat accataaaga aaaaagcaat caaaggaaac tcctccgatt gctcaattct
    42601 tttttgaacg gattgaactt ataggaagtt tttgtctata ccaatcagtg tagaaagaac
    42661 taccatgtaa tgattctaga acactgatat taataaaaca agcaaaaatt cattttttta
    42721 tgttttttta actatctcag ctatctatcc tctttatacc attatttttt tcaaatagtg
    42781 acctgtataa ctttctttta cgttaatgat ttcttctggt gttccagtcg caaggatcgt
    42841 tcctccacct tctccacctt ctggtcctaa atcaatgata taatctgctg ttttgattac
    42901 atctagattg tgttcaatca ctaaaactgt gttaccagca tctactaatc tttgtaatac
    42961 atgcaacaag cgggcgatgt catcgctatg aagtcctgtc gttggttcat ctagtatata
    43021 gaaattcttt ccattagaga ttttgtgcaa ttcactggca agtttcatcc gttgtgcctc
    43081 accaccggac aatgtcgttg ctggttgccc catcgtcaca taacctaagc caacatcaac
    43141 aatcgtttgc agtttgcgat gaatctttgg aatgtgcttg aagaattcta cagcatcttc
    43201 tactgtcatt tccaaaatat cagcaatgct ttttcctttg taatgcactt ctaatgtttc
    43261 agagttatat cgtttgccat gacatacttc acaaggaaca tagacatcag gcaaaaagtg
    43321 catttcgatc ttaataattc catccccgcg acaagcttca caacgaccgc cttttacgtt
    43381 gaaactaaaa cgccctttct tataaccccg catttttgcc tcgttcgttt gagcaaataa
    43441 cccacggata tcatcaaata cacttgtata agtcgctgga ttacttctcg gcgtccggcc
    43501 gattgggctt tgatcgatat cgatgatctt ttcgatactt tcgtagccgg aaattgtctt
    43561 gaatttacct ggcttagcag aattcttatt taatttttgc gctaacgatt tctttaagat
    43621 actattgacc aatgtactct ttccagaacc agacacacct gtgactgcta caaattctcc
    43681 taatggaaat tcaacactaa tatttttcag attgttttct gaagcaccag tgatcttgat
    43741 tgctttccca ttacctttac ggcgttcttt tggtacaggg attgattttt tccctgaaag
    43801 atatttccct gtcaaagaat tttcatcatt agctacttct tcaggagtgc ctgcagccac
    43861 gatttgtccg ccttgttctc cggccccagg tccgacgtca atcagataat ctgctgccca
    43921 catcgtatct tcatcatgtt cgactacaac gagggtgttg ccaagatcac gcattttctt
    43981 taatgagcca atcagtcgat cgttgtcgcg ttgatgcaat ccgatcgatg gttcatctaa
    44041 aatatacaaa actccagaaa gattcgatcc aatttgtgta gccaatctga ttcgctgcgc
    44101 ttctccccca gataatgttc cggaagcgcg actcaaagtt agatagtcta gtcccacatt
    44161 ttccaagaat gaaagtctgt catttacttc ttttaaaatc ggtttggcaa ttactttctc
    44221 ttgttcagat aacgttaagt ttgagaagaa atctactgct ttttgaatag acaactcatt
    44281 tgtttgcccg atattcgttc cattgatttg aacagataga gcttggggat tcaatcgata
    44341 acctttacat gtctgacaag ttaattctgt catataaaga cgcatttgct cacgcgtgaa
    44401 atcactgttc gtatcatgat aacgacgctc gatattcttc aatacccctt cgaaagtcgt
    44461 ttctacatcg cgaacgccac caaaatcatt ttcataatgg aaatggaaaa gatcatctgt
    44521 cccattcaag atgatatcct gatgctcttc cggtaattct tcgaatggtg tatctaaatc
    44581 gataccgaaa ctttcacaag cctgcgctaa catttgagga taatactgag agctgattgg
    44641 attccatgga acgatagcac cttgactaag tgtcttcgtt ctatctggaa tcactaaatc
    44701 ttgatcgact tctaatttga cacctaaacc atcacagtct ggacaagctc caaaaggcgc
    44761 attgaatgag aacagtcttg gttctagttc gccaacagta aatccgcaat aaggacaggc
    44821 atagtgttcg ctaaacaaca tttcttcttc accgatcacg tcaaccagag catagccgtc
    44881 tgccaatcgc agagccgcct ctaaagaatc aaatagacga gaacgaatcc cttctttcac
    44941 aatgatccgg tcgatgacga tcgcgatatc atgttttttg tttttctcca gctcaggcac
    45001 ttcacttaaa tcatagatct caccatcgac tcgaacgcgg acgtatccct ctttttggat
    45061 tcgttcgaat atttttttat gttgtccttt tttctttacc acgatcggtg ccaacacttg
    45121 gatctttgtg cgctcaggca aagccattac ttgatctgcc atttgatcta ctgattgact
    45181 ggtaatctcg atatgatcgt tgggacaaat cggatgtcct acacgtgcaa acaacaagcg
    45241 taaatagtca ttgatttccg tcacagtacc tactgtcgac cgaggatttt tacttgttgt
    45301 tttctgatca atagaaatcg ccggactcaa tccgtcgatg ctatctacgt ccggcttatc
    45361 catttgtcct aaaaactgac gagcataagc agaaaggctc tctacgtatc tccgctgccc
    45421 ttcagcgtac agcgtatcaa atgctaggga actttttcca gaaccggaca aacctgtaac
    45481 gaccacgaat ttatctcgtg gaatcgttac atctatattt ttcaagttat gggcacgtgc
    45541 accgtgaatc gtaattttat cgttagccat gttgtcctcc tactttgaag cttttaattc
    45601 taaaatcata tctcgcacat tagcggctgt ttcaaaatcc aatgctttcg ccgcattttt
    45661 catttctttt tctaatttca tcaataacgt atctttttct tctttcgtca tttcttcata
    45721 cgagacttgt accgcttctt ttgtatcatc ttccgattct ttcgtaatag aaatcaaatc
    45781 tcggatttct ttaatgatcg tttttggaac gatcccatgt tcttcattgt acttctgctg
    45841 aatcgtacgg cgtcttgatg tttcatccat cgctagacgc atagaatctg ttactttgtc
    45901 tgcgtacatg attactttac cttcttcatt ccgagcagct cgtccaatcg tttggactaa
    45961 ggaacgttca ctacgtaaaa agccttcttt atccgcatcc aagatagcaa caagggaaac
    46021 ttcaggtacg tctaatcctt cacgaagcaa attgattcca actaacacat caaattcacc
    46081 taatcgaaga tctcgaatga tttctgttcg ttccagcgtt ttgatatcac tatgcaaata
    46141 tttgactttg atccctaatt ctttgaaata atctgtgagg tcttctgcca tttttttcgt
    46201 caatgtcgtt acaaacaccc gctggtcttt ttcgactcgt tcatttattt cgcctactag
    46261 atcatcgatt tgtcccatga ttggacgaac ttcgatcact gggtcaagca gccctgtcgg
    46321 acggatgatt tgttggataa cggtatctgt ttgttcatgt tcatatggtc ctggcgtcgc
    46381 agagacataa atgatctgat tgacatgttt ttcaaactct tctaaccgaa gtggccgatt
    46441 gtctaaagca gatggcaaac ggaaaccgta atctactagc atctgttttc tcgctcggtc
    46501 accattatac attcctctga cttgaggcat ggttacgtgc gattcgtccg ccacgatcaa
    46561 aaaatcttca ggaaagaaat ccaatagcgt ataaggcggt tcaccttctt tacgtccgtc
    46621 catatgccga gaataatttt caattcccga cgtgtagccc atttctaaca tcatttcaat
    46681 atcgtaattg gttcgctgtt ctaaacgttg agcttccaga agtttgtttt catttcgcaa
    46741 gacagttaaa cgctgttcta attccgcttt gatattcgct acggcatgct ccatatgttc
    46801 atcattcgtc acaaagtgag tcgccgggaa gattgccacg tgttccgttt ctcctaaaac
    46861 ttcacctgtc agtgcattga cttctcggat acgttcgacc tcatctccaa aaaactccac
    46921 acgtaaggca cgttcatctc ttgaagccgg aaaaatctcc acgacatcac cgcgcactcg
    46981 aaaacgaccg cgctgaaaat ctatatcatt tctttcgaat tggatactga ctaagtcacg
    47041 aatcaactga ttgcgatcta gttctgctcc ctgtcgaatc gaaactactt gtttttggta
    47101 ctcaaaaggc gaacctaatc caaaaataca tgaaacggat gcaatgacga tcacatcatt
    47161 tctttctaat aatgaactag tagccgaatg tcgtaatttg tcgatctcat catttacact
    47221 tgaatctttt tcgatatacg tatcgcttga aggcacataa gcttcaggct gataataatc
    47281 ataataagaa acaaaatatt caacagcatt gttagggaaa aattccttga attccccgta
    47341 cagctgacca gccaatgttt tgttatgggc aataattagt gttggtttat tcactttctc
    47401 aataagattg gaaatcgtat atgttttccc tgttccagtc gcacctaata agatttgtgc
    47461 ttttttcccg ccgactacgc catccactaa ttggttaatc gcttcaggct gatcaccagc
    47521 cggttggtat ttcgagacaa gctcaaagtg tcgggaggta tctctctcaa tcattcttcg
    47581 tcctcctttt cattcattcc ttttcatttt acgaccaata aaaagaaaag gaaagcaaag
    47641 gcattcctta ctaaaaaatt ataccacacc gaacatactt tcgccacttt tttatcttat
    47701 tatgcatgtt acgttttata acataaaatg ttagaaactc gcattttttt cattttttcg
    47761 agcttacagt cttgtctgat tcagcacttt tcgcctataa taataaaata ttggaaattt
    47821 aggaggttga ttatgaaaag aaagcattta tttcactcat ttgttttctt aatgacagga
    47881 cttgtgacac ttgcgtttgg acatgttgca caagctgaca acactacaac ggcagagtca
    47941 agcacaagcg agacaatgca aaaaatagag cccaaaaaag acgtatacgt aattgccagt
    48001 gactctgctt ttgctccatt tgaatttcaa aacgcaaagg gcgagtacga aggcatcgat
    48061 gtaaaattga tggaaaacat cgccaaactg caaggattta acatccgaat ggactaccgt
    48121 ggtttctctg ctgctttgca agctttggaa tcaggacaag cagacggaat gattgccgga
    48181 atgactgtaa cagatgaacg aaagaaaagc tatgattttt ctgattctta ctttgatagc
    48241 gggatccaat tagctgtcaa aaaaggagat acttcgatca agtcttatga agatttgaaa
    48301 ggaaaaacag tcggagcaaa agttggtacc gaaagtgctg aatttttaag cgaccatgaa
    48361 tctgaatatg gctattctat caaatatttt gatgctgctg atcaattgta cgacgggtta
    48421 aaagttggcg caatcgatgc aatgatggat gattatccgg taatcggtta tgcgatcaaa
    48481 caaggacaag aattggaaac accgatcaaa aaagaatctg gcggaaaata tgcatttgcc
    48541 gttaaaaaag gacaaaatcc tgagcttctt aatatgttca atgaaggatt gaaagaatta
    48601 aaaagaacag gcgaatacga taagattatt aaagaatatg tagcggatgg ttcagaaact
    48661 tccagtgagt cttccactgc tgatgaatca acatttcttg gacttatcca aaacaactat
    48721 caagcattgt tgaaaggact ttggagaaca attctcctaa ctttgatctc ctttgctttg
    48781 gctatagtaa tcggtgtgat ttttggatta ttcagtgtag caccaatacg cgctcttcgc
    48841 acaattgcta gtatttatgt cgatatcatc cgaggaattc caatgatggt tcttgcgttc
    48901 tttattttct ttgggttgcc tggtatcgtt ggatttacga ttcctgactt ccttgctggt
    48961 gttatcacct tgactcttaa cgcaagtgct tatatcgcag agattgttcg aggcgggatc
    49021 aacgccgttc ctgtcggaca aatggaagct tccagaagtt taggtctttc ttataatcgg
    49081 acaatgcaaa aaatcatttt gccgcaagcg atacgcatca tgatcccatc attcgtcaat
    49141 cagttcgtta tctcattaaa agacacaacg atcatttccg caatcggtgt agtcgaattg
    49201 ctgcaaactg gtaagatcat tgttgcacgt acaacacaaa gtacgtatgt ttacttgatc
    49261 attgcgatca tgtacttgat tttgatcaca gcattgacaa aattagcaaa agttttagaa
    49321 aagaaggtga agtaagatgg cagaaaaaat cttagttgag catttagtca aaaaatacgg
    49381 cgataacaca gtattaaacg acatcaatgt gtccatcaac gaaggagatg tcgtctgtat
    49441 cattggccct tcaggttcag gaaaaagtac atttttgcgt tgcttgaatc gtttagaaga
    49501 accttctgac ggtgaaatta ttattgacgg cgcccacttg atggataaaa gcacagatat
    49561 caacttggtg agacaacata tcggaatggt attccagcac tttaacctat tccctcatct
    49621 ttctattttg gaaaacatca ttttagcacc gatggacctg aagaaagaat ctagagaaga
    49681 agcagagaaa aaagcaatca aattgctgca gacagttggt ctagaagata aaaaagatat
    49741 gtatcctgaa atgctttccg gtggacaaaa gcagcgtgtg gctattgctc gtgctctagc
    49801 gatgaaccct gacatcatgc tttttgatga gcctacatct gcactcgacc ccgaaatggt
    49861 cggtgatgtc ttgaacgtca tgaaaaagtt agcagaacaa ggtatgacga tggttatcgt
    49921 tacgcacgaa atgggcttcg ctaaagaagt ggccaatcgt gtcatgttca ttgacgacgg
    49981 aaacttttta gaagacggaa cgcctcaaca aatctttgaa aatccgcaaa atgaacggac
    50041 aaaagatttc ttgaataaag tattaaatat ttaataaaaa ccaaaaatgc ccggtcgctt
    50101 catgacgacc gggcattttt agtttcttgt tttttcactt aactgtacca gccgcatcgc
    50161 ttgttctcct gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat
    50221 cggttcattg acgatatcaa gtacatagtc gataccacct tcagaaacta tgatgattat
    50281 cttattctaa agctggcttt tttgttggta caaacatgac aactacaaaa aaaccaggcg
    50341 aacgtatgat tgttcgtctg gtttttaatt attaatgact tagcgttttt actagaaata
    50401 gaaaatttgg gcaagtctac tttatatttt tactagaaaa actacttccg ctttttcccg
    50461 ccaaaagcat ctttaaactt atcgaagaaa ccgtcttctt gctgttcttc aactttgatg
    50521 ccgccagctt cagcgaatgc acgtaatgct tctctttgtt gttcatttag atttttcggt
    50581 gtgatcagtt ttactttgac atgttggtcg cctgttgcac caccacgtaa cttcggagcg
    50641 ccttttccac gtaaacggaa gttcgtacct gtctgtgttc cagcagggat cttcaatttc
    50701 acatctccat ggacagttgg tacttggact tcatccccca aagctgcttg tacaaaactt
    50761 aaaggcaatt catagtaaat ttcagaacct tcacgatcaa agatatcact ttcttctaca
    50821 cgaaaaacca catacaaatc accaaatggt ccgccgtttt ctccagcttc tccttgacca
    50881 gctaaacgca tttgttgtcc ttcttctaca ccagctggta cattcacttt aactgaatgt
    50941 gctttcttct catgtcctga gccatgacag gttggacaag gttctttgat ttctttccct
    51001 gtgccatgac aaacatcaca agtttgacgg ctcatcactc gtccaagtgg cgtttggcgt
    51061 tctacattga tcgtacctgc accatgacat ttatgacaag tagttggttg tgtgcctggt
    51121 tttgcaccgt ttccaccaca agtatgacag atttcttccc gattatactt gatttctttt
    51181 tctacaccaa aaatcgcttc ttcaaaagac aagtcgaccg tatattgcaa atcagcacct
    51241 tgacgaggcg catttggatc gactgaccga ccgcctcctc caaagaaaga gtcgaagata
    51301 tcttcaaaac caccgaagcc gccaccagag aagccgccga atccaccaaa tccgccacca
    51361 gctccaccag caccgtaatt tggatctgtg cctgcatgcc cgtattggtc gtatgcagcg
    51421 cgtttttgcg ggtcacttaa aatctcatat gcttctgata cttctttgaa tttttcttcc
    51481 gcatcaggtt ctttattgat gtcaggatgg tattttttcg aaagcttacg ataagctttc
    51541 tttatttcat cttctgatgc tccttttgag agccctaaga cttcataata atcacgtttt
    51601 gttgccatag gctttcctcc tattggttct catcattttc acgtcgcttg ttatcatatc
    51661 atattttgtt tgaaacaaaa accgatactt caaactattt ttcaaaagaa aaagccaaag
    51721 tagcaacttt ggccttctct cgaaattcag tgaactgatt atttatcgtc gccatcgact
    51781 tcttcaaaat cagcatcaac gacatcatct gctccgcctt gagctgcttc tggattttct
    51841 tgagcttgtt gttgtgcagc ttgttcgtat agtttaacag tcaagttttg aacgatttcg
    51901 ttcaatgcat cgcgtttagt tttcatttcc tcgatgttgt ttgcttcaac agcggctttt
    51961 aattcgtcac gagctgtttc tgcttttttc acttcttctt cgtccacttt gccttctaat
    52021 tctttcaatg ttttgtccac agagaatagc aatgcgtcta catcattacg taggtcaact
    52081 tcctctttac gagctttatc tgcttcagcg tttgcttctg catctttcac catacgttcg
    52141 atttcttcgt ctgttagacc tgaagaagat ttgatcgtga ttttttgttc tttttgtgta
    52201 cctagatctt tcgcagatac atttacaatc ccgtttttat caatatcgaa tgttacttcg
    52261 atttgtggaa taccacgagg agctgctgga atatctgtca attggaatct tcctagagtt
    52321 ttgttgtcag cagccattgg gcgttcacct tgtaatacat ggatgtctac tgctggttga
    52381 ttatctgccg cagttgagaa tacttgtgat ttacttgttg gaatcgttgt attgcggtca
    52441 atcaatttag tgaacactcc acccattgtt tcgataccta atgacaatgg tgtaacgtca
    52501 agtaaaacaa catctttcac atcaccagtg atcacgccac cttggatagc agcacccata
    52561 gcaactactt catcagggtt aactgatttg tttggttctt ttcctgtttc tttacgtact
    52621 gcttctacaa ctgcagggat acgagtagat ccaccgacta aaataacttc gtcgatttct
    52681 gattgtgaca gacctgcatc ttttaacgct tgacgtactg gtacttttgt acgttctact
    52741 aagtcagctg ttaattcatc aaattttgca cgtgtcaatg tcatttccaa atgcaatggt
    52801 ccagattctc ctgctgtgat aaatggcaag ctgatttgtg tgcttgatac gccagataaa
    52861 tcttttttcg ctttttcagc agcgtctttc aagcgttgta aagccatttt gtcttgagac
    52921 aagtcaatgc tgttttcttt tttgaattct gctaccatgt agtcgatgat tttgttatca
    52981 aagtcgtccc cacctagatg gttgtcgcca gctgttgaca atacatcaaa gacaccgtct
    53041 cctagttcaa ggatagatac gtcaaaagta ccgccaccaa ggtcgaatac taagattttt
    53101 tcgtcgcgat ctgttttatc taaaccatag gcaagagcag ctgcagttgg ttcattgacg
    53161 atacgttcta cttctagacc agcgatctta ccagcatctt ttgttgcttg acgttgtgca
    53221 tcattaaagt aagctggcac agtgataact gctttttcga ctttttcacc taaatagtct
    53281 tctgcgaatc ctttgatata ttgaaggatc attgctgaga tttcttgtgg tgtatatgat
    53341 ttaccttcta catctacttt gtaacctgct tcaccgatat ggcgtttgat tgatgaaatc
    53401 gtatttgggt ttgtcacagc ttgacgtttt gcaacttccc ctacttggat ttctccattt
    53461 ttgaatgata caacagaagg tgttgtacgg tttccttctg ggttagcgat gatttttgct
    53521 tcgtttcctt ccaatactgc tactgcagag ttagtcgtac ctaagtcaat accgataatt
    53581 ttactcataa ttaacgtctc cttctttaat tgaaagtgta agttttatat ccgcacaatt
    53641 attgtgcaac aatgaccatg gttggtctta acacgcgatc atgtaatttg tagccttctt
    53701 gtagtacttc tacaatcgta tcggctggtg tatcttcagt cgctggaaca gtttgtactg
    53761 cttgatgaag attaggatca aaggcttctc ctttagcagg gattttttca attccttctt
    53821 cttccagtgc gttacgcaaa ctttccaaga ccatttccac gccttttttc aaacctgccc
    53881 cttgatcatc tgacacttct gtggctaatg cacgttccag gttgtcaatt gatggaagta
    53941 attttttggc taaatcttgt gaacggtatt tttgtaattg ctcacgctca ttttttcctc
    54001 gatttgccat atttgcgatt tcagcacgag cccgcaagta tttatcttcc atttcttcta
    54061 actcagcttt taatttcgct gtttcgaatt cttccgcttc agcttctgaa atacccgaat
    54121 cttctgcagc ttcgacatcg atttccggtt ctggctgagc atctgtcatt tctttatcta
    54181 gttcttcttg attttctttc acgatacagt cttcctttca ttattcagtc agctgtttga
    54241 ttgctcttac taagaaagag agaacgatca gctgcaaata gcttcgttat tcacattacg
    54301 agtttgacaa gtcaagcgaa cggtagtaat cagcaagttt agctgctagt tctcttcgat
    54361 aaacatcgac tagaccgaac atccgagaat aaggcatact agtaggccct aacaaggcta
    54421 ttgtacctct tccatgacca tctatctcgt aacttgcttg aatcatactc atattctgca
    54481 ataaatcatt gcctaattca gcaccaatct tgatatgaat attgctatcc atcggagtga
    54541 tcatttgtgt aagtccgtct gagtctttca taaaagaaaa catcgatttg aactgatcaa
    54601 gatcttgacg gggctcataa tccaagagat tcatttgtcc actgacataa accttatctt
    54661 caaaaacatg accaagaacg gtgtcaaata actgagacat cccttctgtc gtttggaaat
    54721 atttatgaag aatcatcgga atctccgtac gaagtttatg gtacaccgtc atcagaggat
    54781 ctccgactag acggtcgttt acaatctgta ccattttttc tagttcctga cttcccatat
    54841 attcgggaag agtgaacact tggctttcta cattccccat atctgttacg acgatagcaa
    54901 taatctgtcg attattcaag ggtacgatac gaaagccagt cagtcggcgg tcttttattt
    54961 caggtcccaa tgaaaaagtc gtatagcttg tcagctcaga taatatctca gcagattgct
    55021 taataatctc attgatttca tgaaattctc tgcctagaga ctgacgaatc agcagcaaat
    55081 catcttctgc tacgcgagca ggttttaaca aatgatccac gtaataacga tagcctaaag
    55141 cagatggaat ccgcccagaa gaagagtgag tcttcaacag caatccttca tcttctaatg
    55201 ctttcatatc attgcgaatc gttgctgagc tggccttgac tccctcagac atcaatgttt
    55261 tggaaccaac gggcacgcca ctactcgtat agtgttggat gatcagacgt aaaatgtcgt
    55321 tttgtcgctt tgttaacatc ttcctcacct ctcattagca ctcatatatt ctaagtgcta
    55381 atccacttat aaatatagca agaagccctt ctcctgtcaa gagaaagact ccatttttta
    55441 gcactctaaa cacaagagtg ctaattctaa ataattgatg taaatccagt tatatcaacg
    55501 tttcaatagt cctttattgt atttttgaac tttttttatt taaattcaga taaaaaacaa
    55561 atattcttta aactattttt caaacaaaaa gcgctcaaac acattgttcc ccaaaaaggt
    55621 ccctcttggt gtcaaataaa cacggtcttc ttcattaaca agtaaccctt cttgctctaa
    55681 ttcccttagc acatcaccgt acaccgattc aattgttttt tgatagcgat catagaaatg
    55741 ttttttagta atccctgttt tttttcttag tcctaagaac atttcttctt ctatttgatt
    55801 ttttcgtgtc aatttttctt cttccaatac cgggcgttca tttgctcgta atgggcgtaa
    55861 atagtgttgg attggtcctt tgttgcggta acgaatatct ccaagataac cgctagcacc
    55921 agctccaaac ccaaaatagt gggcattgtt ccagtacatg aggttatgtt gagattcatg
    55981 tccggagagc ccaaagttac ttatttcata ttggtgacgt ccatgctttt ccattgcttc
    56041 aatcgtctct tcaaacattc tggtttccgt ttcctgatca ggcagttcga gtcttccttg
    56101 tcgtacccag ttcatgaaca ttgttttgtt ttcgaggatc aatgagtaca aagaatagtg
    56161 aggcagatcc aaagccaaag ctttttccaa agtatccaga tatccttcta gtgtttgtcc
    56221 cggtaatgca taaatcaaat cgatgcttac attggtaaaa ttttctgctt ctaaaaattg
    56281 catagtttga tacacatctt ctgcggtgtg tttacgtcca atttttttca ataagcgatt
    56341 atcaaatgtc tgcactccca tggataaacg attgacgcca tagtttttca ttacttgaag
    56401 tttttcacgg gtcaaatcac ctggattcgc ttctacagta aactcattac cattttgaaa
    56461 aggcaggatc tctctagcac ctgataacag tcgatcaagt tgtttagcag ataaagaagt
    56521 tggtgtcccg ccccctacgt aaagtgtttc taaattcgct gtcggatgac tttctagcat
    56581 tattttcatt tcattcagca gcatttccac atactcatct actggctgcc cttctaaaaa
    56641 aactttatta aaatcacagt aatagcagat atgctcgcaa aatgggatat gaatgtacgc
    56701 agaaaccttg ttttctgcgg gatttattgt ttctatcatt gaaattcttt ctccttacgt
    56761 cgaaaagtcg tgcctgtttt cgaccttctt aaaatcgcgt tcaagcacca actcattgaa
    56821 ataagccgca tatttagaat caaggaaacc tagctctaaa aatgcttgct tattgtcatc
    56881 ggagctacac ggtgctttta cagcctctcg ataaacggta atcgcaaagc tgaccttcgg
    56941 cattaagtca aaatctgcaa aaatatgaaa agctattttc acagattcct ccttaagtgc
    57001 tcagaccaca acgctttgct tacaacctct catatacgca tactaaacgt atttggcgaa
    57061 caaatccact aaaaaatcca agaatcgact tcttggatga ttttttcttt cattaaactg
    57121 gttacctagt tatatatctc tagggttgtt ttcatgtctg agtgcccgat atgatttatt
    57181 tttcgtttct ataattactt tttgccttcc agtttctttt aatattgtac tcaagcaagt
    57241 gggaattggt tcttttgtca tccatgtatg caaaatgtta taatgctggt aaacaaaaat
    57301 gattacctgt catttttatt tagttcgtat ttaattaagt tgactatctg tatactctgt
    57361 ctaaaactta agaattgttg ttttcgctgt cgctacccaa ttttaatgaa tgtctgtagg
    57421 ttaaaactgt tgtccttgtt atagatagta aaggagagct tgaaaatgaa aactgcgatt
    57481 acgtttctat tagaggaata tgccgattgg gaaggtgctt atattactag cacactaaac
    57541 caaaatgaga aatggcaaaa caaaactgct tctatccaat cagaggtcac ttccattgga
    57601 ggattaaaaa caaaaatcga ttacttaatc gaacaaatac ctgaaaaagt tgaccttttt
    57661 attatgatcg gtggcaattc atgggacata aaaaatcatc atttatatca aataatcgat
    57721 aaattgttaa aaacagacgt accagtagct gctatttgtg gggcagttga ttatttagct
    57781 cagagcggat tattgcaagg ttacaaacac accggaaatg cgcaatttcc ttggttagaa
    57841 tcggaaaatt atcagaataa agaagatttt atagaacaac aagctgtgaa agatcgtaat
    57901 ttgattactg cgaatggaac agctcctata gaattcacag acttgattct tcaagcagtc
    57961 cattttgaaa cagaagaaat aagagaaaaa acgattcgtc tatacaaact tggattctat
    58021 gattactata aaaagtacgg agatcctttc tcctaatcat tctcttcaat taaatactcc
    58081 ttatcaatag tgtgacaagt aattttactg atgattattt gtcacacttt ttctgacatt
    58141 tatcaaagaa gatacactct atttatattc atagacaagg ttttacggat tcaaaaattc
    58201 aggattatgc tatactggta ttaaaaaaat aatgaggtat tttatatgaa aaagttaggt
    58261 tttattttat tgttggtctc tttattcctt gtaggatgta cgtctcctag taaagaaaat
    58321 agtgatccat ctgcgaccac agacaaaagt tcaatcagac aaaccagttc agctgaaaaa
    58381 tcaagtactc agaaatcagc ttctactgaa acgaatacat cttcaacaag cagtaaagtc
    58441 tcagagccca atacttcttc tacatctagt agtacagttg agacaaatat ttcttcttca
    58501 acaatagaca caacctcctc acagtcttct cagtcaatag atccgttagc aggatattct
    58561 gatctacaaa ttgagtacgc acgtgtttgg ctagctatta gaggtaatac ttttagagat
    58621 acatcgggtg atttcgaatt acatgttatt cattatcctg caggaacacc tatcgcccct
    58681 tatgatgcag ggagtgcagt ctatccgaaa gatgtggtta tgctcactgg gaaatacagt
    58741 taccagggag ttttagtgta ttcaagtaac catgacggga caatcactag ttatccagtt
    58801 ccttcacatt ggcaaatgcc tgcagatcaa acatcttatc cagcgttcat tagagaaaca
    58861 actcaagaaa tcattgataa tgcatctgta gtagctattc ctacaggaaa tcccaatgac
    58921 gtgaaacagt taatcgatgt gacagttata gataattaga ctttctaata tgttatacaa
    58981 aaagaagctg acagcatttt gtcagcttct ttcactttct tttctattta gatttattgg
    59041 tctttgatag actccaaggc aggaaaaaat tttttaaata aacgtttgca aaacagtcgc
    59101 ttttctatct tctaccgcta cttctgcata ggcaccatta atcaatgtca gttgtggcgg
    59161 tacatgacca caatcaatat catacaagat cggtagtttt aattcctttg acagatcttc
    59221 gtatacatcc ttcattttat aatctaacaa atcctctgcc gcacttctac cgaacatgat
    59281 ccccgagctg ccatcaaacc agcctgccag tttcatctga acaagtgatc ttcttaaatc
    59341 aactgacgat agctcacagt tttctagaaa ccacaagatc ggctttccat cattatactt
    59401 tcttttaaaa gattggacat ctccataagg agtaccgatt aaatgcctga tcgtatcaat
    59461 acaaccacct aataatcgtc ccttcatcct tactgcatct ccgctgactg attgccaatt
    59521 tgttggttca gtgagatgga aaacagaaga tgatgaatgc tcatggggcc acactttttg
    59581 atacttttca gaagattgct gtagaatcga ttctccttct cttgttttca gtacactttc
    59641 ccacattgct gtcgtttcat ccaagtactc tcctcttaaa tcaataaggt tagttccatg
    59701 tgcagtggct atccctgttt ttaatgtgac agcaagtagc aacgtactaa tatctgaata
    59761 acctactatc cattttggtt gtagagcatc aaaatcgaca aaatcgagaa tctcaatcaa
    59821 taattctcct ccccaagtcg gaaagatcat ttggatattt tcatcttgca tcatttgatt
    59881 gaattcatct gctcgttttc ttgctggacc tgatttttcc ttatcttgcg tccaaagcgt
    59941 ctttccagta actacttgga aagatttttc ttccattctc tttaaagctg attcgagtaa
    60001 cgaatggtgt tcctctgata cgcctgagga tggtgcagta accccaatcg ttgcatttct
    60061 ttctaataat ggataactta tcatgttgct tcacctccaa gtatgcacta ttttacttgg
    60121 ttaattgttt ttttcgtttg ccggcatcaa aaatatcggc atctcaagta gctggatgat
    60181 tttgtttaag tcaaccgttt ggatgaccat cgtttgatct ggtctacctg gtgcaaaaac
    60241 aagtttttca tttgataaga gctcttcatc aataataatc ggaatctgtt tttcataacc
    60301 aaacggagaa acagcgccct gcttttgtcc cgtttgttct tccatgcgtt ctgatgaaac
    60361 aatagaaagc cttttaccga cgatcttccc taatgctttg aaatccgttt gtttcgtagt
    60421 aaaagtcaga tatacgtagt tattatcttt tttatctttt aagaataagc ttttggtctc
    60481 tgtacctgta aatccttgtt ctttctttat taccaaagca tcttcatttg tataaatggc
    60541 tcgatgatga tacaactcaa aatatatatt ttcgtgtaag aatttctttg ccaagtcaat
    60601 catttttatg tctcttttct attttattat ttgagacatc ttatcatata aatatagcgg
    60661 ttacaacatt acttgtgttt tgttcgtttt ttatacataa ctattgtttt tctggtaaaa
    60721 taaatcaaac cacttaatgg aggcgtttta gaatggaaaa atttcagccg atcatcaatc
    60781 aaatcaaaga aaaagaacat caacaaaaga tcaaagacct ttttgctaag ataacagaaa
    60841 cgtatcccca gctagacaca actgtaaaat ggaaccaacc tatgtttact gaccatggta
    60901 cctttattat tgcatttagt tttgctaaaa atcatttttc tatcgcaccg gaaaaagcag
    60961 cgattcgtgc ccttgaaaaa aatatccaag aagcaggcta cgtatatacg gataacgtca
    61021 tcaaagttcc ttggaaaagt gtaatcaact gggaattgat tgaacaattg atttcattta
    61081 atattgaaga taaaaaaggt catgataaat tttggcgata aagctttata cgaataaacc
    61141 ttttactggc gaggaaacta ttcatcacct tatacaggtt ttgttcaatc ctatcctttt
    61201 tatcatccct ggttaaacac ttaattgaca aagtatctgc tatttttata aggagtcttt
    61261 cttgtgctga aaaaaatcac tgattgaatg gctttgaatt ttctacttag taaaattatt
    61321 ttttcagcaa ttttcctgca aaacttttga ataaggaaaa aatacgagaa aatatcagtg
    61381 atctttcata atactgccca ttattttcag gtatatttaa atataatatc actttaggag
    61441 agaacgaatt tctttagaga aataaaagtt agaattttct gacttgattt ttacaatgac
    61501 cttaattaaa atcgttcttt ctacatttcg tgattaagca aatatcaact aagtcagtag
    61561 aaccattcac ataggagggt gaacattgaa agatttttac tcagtaaatg aattagccga
    61621 acaattaggt gttactacac gttctatcag aaattatctt catgaaggaa aactaaaagg
    61681 aacaaaggtt ggcgggcaat ggaaattttc tgaacgtaat ctttttgagt tcctatacgg
    61741 agatcaagca gaggaagcag caaaagaaat gcagcgattc atgctaaatg caccaatcac
    61801 gatgcgtttc aaccttcaat atcgtgattt tacagcaatc aatcaattcc gagaacaatt
    61861 agtccagtac cataacgatg tttacgcaaa taaaaaagac cgtcttttac aatacgatct
    61921 ttataaagac aatcatgcgg agatactaat cggtggtaac ttcaattatg tcgtaaactt
    61981 tagtcaatgg atcaatgaaa aattattgat ccagacagat atttcccttg tatcttaaac
    62041 aattaaaaag cgctagaaat tccagagatg ttggaaattc tagcgctatt tttttataag
    62101 tacttactgt ttggttcaaa caaatatttt tttaataaat gaaattttac catctttatc
    62161 ctcaaataaa gaccgtgacc atgcttccta ctacgatcag caataatccg ataatcgtta
    62221 attttttttc ttttggtgtc ttattttcat gcaggatgta cataccgcct aatgtagaga
    62281 taactacgtt tagctgtgta atgatatatg cagtagcaac cccattttca tttgctgaaa
    62341 aaatataagc caatgctgac acactaaaga tggctccaac gatcgttgct ttccaactct
    62401 tgtcttcaga aaatgcggtt ggtttacgga aaatcacata aatcactgcc cctaaaaaga
    62461 caccgatcat ttgcggaaag aaaatggaaa gtccgcttgc atcaactagt ttaggcaatg
    62521 cactgtatac ccaataacca atacttgttg atgctaatag actaattcct tttgtgatac
    62581 cgcctttttt tccaggatca tcactgattg ccgttaaagc agaaccaaat acaagaagaa
    62641 tgattgctgc tgctccaatg attttcccca tacttccaga ccattctcca aaagcgaaga
    62701 caccaatcaa cgaggttccg actaactgta atgcagtcga aattggcatc gttttagaaa
    62761 caccaatcaa gttgaaagat gtatactgtc ctgtttgtcc aataacccaa aatgcaccag
    62821 aaagtaaact aatcaaaaat gtagtcactg aaataccagc tggagaagcg aataattgaa
    62881 cgagtaagcc gacaagcacc gctccaatac cagttcctaa tatctcattt gttggtctgc
    62941 caccaatctt tttcaaaatc agtggctgga tcccccagcc aactgccggg atcaatgcaa
    63001 tcaataaacc catttttatt cacccttatc cttttccacc ttggaaagaa ggatataaag
    63061 tcatcccacc atctgcaaat agtgtaatac ctgtaacata actggattcg tctgaagcca
    63121 accatgcagc tgtcgccgct atttcttttg gttcacctac gcgtcctagt gggatcatac
    63181 tttccaagag ttctttttgt tcaggatcat caaattttgc cgcattaata ggtgtacgga
    63241 tagcaccagg gcctatacta ttgattctga ttcccttcgg tgcatactcc attgctaccg
    63301 tttcggtaaa taattttacc ccgccttttg aagcagcgta atgagcaaac gttggccatg
    63361 ggatctgttc atgaacagaa gacatattga tgatatttcc ttttttatta ttctctgtaa
    63421 agtaatttaa agccgctttc gttccgataa aaacgccagt caaattgact tttaacactc
    63481 tttcccaatc ttcaaggcta agttcatggg ttggatgctg attttccatc ccagcattat
    63541 taacccaaac gtccagtgtc ccaaaatttt ctaaagccgt atcaagtaaa cgctgtattc
    63601 cttcttcaga actgacatct gcttgtacag agactgcttt tccgcctgcc tcttcgattg
    63661 ctttgactgc tttttctgct ccttctttat ccgagttata gttgacaact acattcattt
    63721 tttctttccc gaatcgttga gcaatcgctg ttccaatccc ctttgagcca ccagttacta
    63781 ctgcgacttt gttttctaat tccttgtaca tagtacccac tcctttttca tacctaaacc
    63841 tgttattacg gataactttt atttccgcct taaagtgagt gtacaccaag atatatagtc
    63901 taaagcaaat gatacgctct agcaatcgtt ttcatgaatt gctagtgtcc ttttatttct
    63961 ataaagaaag aggttgtgac agaagtggtc agcttcaaga aatttcggct tatttccgaa
    64021 gaagctactt ctgaaaaacc atttatttgg aaaaaaaggc tgtgacaaga cttttgtcac
    64081 agcccctttc ctgggcttat ttatcaccca ttttattgta attgctagtt atacataaac
    64141 aagagatttt atgcataatg ttttattgct gagaaaaata ttcagctgtt gcttgttcat
    64201 cctccttgag ttgttcaatc aattcctcta cactagaaaa tttcacttga tctcttaaaa
    64261 attgattcca gcgtaccgcg acatgttcac catagatatc ttgattaaag tccaaaatat
    64321 acaactctac agtcagctcc cgtccttcac cgaatgtatc attatgtcca attgaaccca
    64381 tggctggata ccatgtttcc ccaattttta tttccgacac ataaacacct tctttaggca
    64441 aatgaaccgt gctctttact ttgacatttg ctgtagggaa tcctagtagt ctgcctcgtg
    64501 catcgccatg gacaactacc ccttctacct catatgtgca acctaatagt tttgctgctt
    64561 cttttacttg tccgctgtct agtaatccac gaatacgggt agagctgatt ttttcacctt
    64621 gttcttcttc tttagaaact gtgacgattt tgaatcttcc tttggcatat tcaggaaaat
    64681 gagcgacatc tgcaatgtct tttggtccat acgtataatc aaaaccggaa acagcatatt
    64741 ttgcatgtaa ccctacgatg tattgatcaa caaattcctg cggtgctaaa tgagcaaaag
    64801 aagaagtaaa atcaacttca tataaataat ctatacccaa agcggccatt ttttcttctt
    64861 tttgcttaag gctagtcaaa tatttcacgc tgctaggatc gatcttttta aagacaatag
    64921 atggatgctg attgaaagtc atcaatgcta atttcaatcc ttctttttgt gcaatttcca
    64981 tacctgtctt tatgactttc tggtgtccga tatgcacgcc gtcgaaaaat cccagcacta
    65041 aaacgacatc gtcttctgga atttgttctg attggtaagg atgtctgatc ttgatgatat
    65101 tcattcgtta ttcctcattt ctcaatactt tactaggttt taatttgttt ttttctttcg
    65161 ggtttggctg ataaatactg acaacttttc ctttataaaa caaagcaatt tcttctgacg
    65221 gcatttctgg gagcgcaaat acagtataat caagtctcat accgtttttt actttctgcc
    65281 atacttcatc agtaatatct actcgtttga accgttccac tcctttttct attggcagca
    65341 aacaatcatc gattgtccca tttttcacag cttgagctac ttcttctaat gtcagagcat
    65401 ccttctggga cataccggca cttgctgttc gggtcagatc agacatgtgc gcagggtaac
    65461 caagtttctt gcctgtatct acagctaatg tgcggacata ggttcctttc ccgcattcta
    65521 cttcgaagcg ccaagaaatg gttcctgtca cttcgtctct tgtcaattca cttgtccgga
    65581 taaaacggta aatctgagcc tttctaacag gacgctccac tgtttcatta ttgcgggcat
    65641 attcatataa ccgcttaccg ttgactttta ccgctgagta cattggtggt atctgggtga
    65701 tctcaccaat aaatgaagcc atcacttcat ctattttttt ttcagataaa gacatatcta
    65761 ctggttttgt ttctacccgt tctccggatc gatcttccgt cgttgtactg aaacctagag
    65821 ttatctcgcc tacatagatt ttcccagaat ctgtcaaata ttcgataact tttgtggctt
    65881 ttccaataca aatgggcaac acaccgtcta cgtctgggtc aagcgtaccc ccatgtccga
    65941 tttttttcgt atgtaagatt tttcttaatt tgaatacgca atcatgactt gtcattccgc
    66001 gttctttcca taaaggtaat aacccgtcca tgtcttttct ccatttcatt tttgatttaa
    66061 ctgaattatt ataacacatt gcatcaatta ctgacgaatt tgacatcata atgaacggtt
    66121 tttatttttc ggcaataaaa acgtaacaaa attcatgctc acgtaaatag aaatcatgtt
    66181 atgctttttt aaaggaggga atagaatgga agattttttc tttgcaccat ttgattggat
    66241 ttatgggtgg cttacaggta aatagtttgg ttttcacttc ccaaaaacga aaaaaaagac
    66301 tggccattct tccagtcttt tttccgtttt ttttatttat tttttcagtt tcttaatcaa
    66361 tgtaaaaaat tctattttgc gggatcgatt ttatcatttt attggtcaag atttttccat
    66421 ttccaatcca atacttctgg cagatcaata ccattttcac gaatatagtt ttgatgttct
    66481 tgtaatttct gatccatttt tttcgcaaaa tcttctgctt gacttccttt gatttttaaa
    66541 gctgcgtctt ttgccaaatg ataacgatca agttcattta ctacacgcat gtcaaatggt
    66601 gtcgtgatat ctccattttc tttgtagcca tgaatcatta aatgatggtt atgacgatca
    66661 aagaaaatcg tgcggaccaa tgtttcataa ccgtggaaag caaataagat cggtttgtct
    66721 tttgtaaaat attgatcaaa ttcttcatcg ctcaacccac gcggatcttg acttggatga
    66781 cgtaatttca ataaatctac gacattgatg aaccgaattt ttagttttgg gaattcttcc
    66841 agcagcaaag ttacagctgc taatgcttct aagttagatt ccgttcctgc agcagcaatg
    66901 accaattcag gttcctcctc ttttgctgtc gaagcccaat caatgatttt caagccttca
    66961 ttcactaaga cggctgcttc ttctgctgag taaaattgag cacgcggatg tttggaagag
    67021 atgatcaaat tgattttttc tgacgagcgg aatgctttat ccatgactgc gagcaatgta
    67081 tttgcatccg caggcagata ttcacggatg aactccgcct tcttttctgc caaatgtgtc
    67141 aatattcctg gatcttggtg gctatatcca ttgtgatctt gctggaagac tgttgagctt
    67201 gcaatgagat ttagcgaagg ataatcattt cgccaagaaa ggtcatgtga tttccgcatc
    67261 catttgaagt gctgagtcaa catagagtca accactcgca agaatgattc gtaacttgca
    67321 aaaaaccatg ccgtccagtc agaacgtacc cttctaagaa cccttcatct tggtgttccg
    67381 ataattgact gtcgatgacg cgaccagatg gcgaaagcca ttcatcattt tctggttcga
    67441 ttttttccat ccattggcga tttgtcgttt tgaaaacttg attcaatcgg tttgattttg
    67501 tttcatctgg tccaaatata cggaaatttt ctggattttt ctcaatgatc tcgcgaacga
    67561 atttaccaag ttcggtcata tcttctgctt taacggagcc tggtttttca aattgcaaag
    67621 tatatttttt ccaatctggc ataataagcg gtcttggatc gattccacca ttggtgatag
    67681 gattttttgc cattctttgg tcaccagtag gcgcgatttc tctgatttct tctaaaatac
    67741 gtccttgtgc atcaaataat ttttctggtt cataggattt cagccaacgg agtaaagcat
    67801 ctgcatgatc catatgttct tgatctacag gaatcggtac ttggtgtgct cggaaggttc
    67861 cttcaattgg ttccccgtcc cattcttttg gaccggtcca tccttttggt gtgcgtacga
    67921 tcaatactgg ccattttggc atcacgacat ctgttgctgt cttcaggcga gcttcttttt
    67981 ggatggattt aattttctcg attgcttgat ccattttttc agccataaca ggatttaatt
    68041 tttctgaatc atttccttca ataaagaaag gttcccagcc aagtccgtta aagtaatttg
    68101 ctaattctcc atctgattta cgtgccaaga tcgttgggtt ggctattttt gcaccattta
    68161 aatgaaggat cggtaaaaca gctccatcta tcactggatt gataaagaca tttgagaacc
    68221 agcttccagc taaaggaccg gtttctgctt caccatcacc aatcacgaca gcagagatta
    68281 cttcaggatt gtctaataca gctccgactg catgtgaaag agagtatcca agctctccgc
    68341 cttcatggat agaacctggt gtttctggtg ctgcatgaga agcaatgcct ccaggaaatg
    68401 aaaatcgttt gaataatttt tgcattcctg tctcatcttc cgttacttct ggatagatct
    68461 ctgtgtaact tccatctaaa taagcattcg ataccatgac ttgtccgccg tgtcctggcc
    68521 cttcaatata aaacatgttc aaatcatatt tattgatgac tcggttcaaa tggacataaa
    68581 taaaattttg gccaggaatc gttccccaat gaccgattgg atgttttttg acatcttcgg
    68641 gtttcagtgt acgtctcagt aaggggttat ctttaagata aagttgccca acagaaagat
    68701 aattagcagc acgccaccaa gccgtcattt tatcaaagta ttctttacta gaataatcca
    68761 tacataacac tccttttcat tattactctt attctagcgc agatactccc aattgaaacc
    68821 taataagcac ttctgttcat ttgtttggat tttatatcta gccaaatgaa caggtataaa
    68881 aaaccacgaa atttttcctt tcgctgacgt tttttacatt gatccaaaaa acttgtcgtt
    68941 atcacaatgg ctgttccgca gttcatttcg ctcctcatca tgcataattt gctgaatgac
    69001 gctgggccag ttaacacatt gctggaaaac tggggctgga tcgagcaatt cctttcctga
    69061 ttgatccgtt ttatgtaaaa gtctctgtta tctttgtcaa tatgtgaatt ggtatcccag
    69121 ctactatgct aatttctaca gggattatcc aaaatttgga tcgtgaccaa atcgaagcgg
    69181 cgtaatcgga aatatcaata acttcaacgt gatttttctt ttaactgtca acggaccgac
    69241 aaactcaaac ttttatggtg caggttccac tgatcttcta gttacttggc tatacctgac
    69301 tgtcactaaa atagattaca atctagcttc cgttatcggt atcttgatct ttatctatat
    69361 gcaaaaattt atatactact agaaaaaaga aagtcgaatt ttttactttt ctttttctct
    69421 tttttggtta gctgacacgc cgcaagacta aagtcatgga actcttaggt aatacgtctt
    69481 aatgaaaaca aaaaaatccc gcaacccctg atttcacagg atttgcggga gtttttgatt
    69541 agtctttgtt caagtcgcga agcaattcat cgatatggtt gccatagaca actgattcat
    69601 caagttcaaa gaacaattca ggtgtcttat aaatacttag attgtgccct aactctcgac
    69661 gaatcaatcc tgatgcttta ttcaatccat cttgtgctgt tttcttatct gatgctaagt
    69721 cagataaaat gctgtaatag atcgttgctt gctgtaagtc ccccgtaact ttcacatctg
    69781 tgatcgttac gttctccaca cgagggtcac ggaccttttt gcgcaaaata tcattgactt
    69841 cttttaagat ttcttgaccg actcggcggt cacggtagtt agccataatg attggcctcc
    69901 ttttatcagt ttttagtcat ttttgacttc ttccatgata aatccttcaa ttacgtcatc
    69961 tactttgatg tcattgaatt tttcaatcat tgcaccacat tcataaccca ttttgacttc
    70021 tttcacgtca tctttgaatc gtttcagact tgcaagttgg ccttcataga ttacgattcc
    70081 gtcacggatt acacggacac cgctatctct acgaatatat ccttctgtta cataggcacc
    70141 tgcaatcgta ccaactttag aaactttgaa ggtttcacga acgatcattt gaccggtgat
    70201 tttttcttca aattcagggt ctagcatccc tttcatcgca gtttcgattt cttcgatggc
    70261 tttatagatg atacggtgaa gacgaatatc gacttcttca gtatcagctt gcacttttgc
    70321 ctgcggtgta ggacgaacgt tgaaaccgat gataatagcg ttgctggctg ctgctaaggt
    70381 tacatcactt tcattgattg ctccgacagc tgaatggacg atttttacac ggacaccttc
    70441 cacatcaatc ttcttcaatg atgcagccag tgcttctgct gaaccttgta catctgcttt
    70501 gatgattacg ttaacttctt tcaattcgcc ttctttcagg ctttcaaata agttatccaa
    70561 agtcacacgg cttgtggcag cacggttttc taataatgca cgtttcgcgc gttcttcacc
    70621 cgctgcacgt gctgtctttt cgtcttcgaa gactacgaaa cggtcacctg cttgaggtac
    70681 atcattcaag ccagtgattt ctactggcgt tgcaggtcct gcttctttat cgcgacggcc
    70741 aagatcgttt gtcattacac ggacacgtcc gtaagtatta ccgacaacga ttgggtcacc
    70801 aacatgaagt gttccttctt ggacaagtaa ggttgacaca ggacctttac ctttatcaag
    70861 acgtgcttcg atcactgttc cgattgcgcg ttgtgttgga tctgctttta aatcttctac
    70921 ttctgcgact aacaggatca tttccagcaa ttcttcgatg ttttggccga atttcgctga
    70981 gatctcaaca aagatcgttt ctccacccca tgcttcagga attaactcat actcacttaa
    71041 ttcttgcata acatgttgag ggtttgcacc tggtttatca attttattta cagcgacgat
    71101 gattggaacg cctgcagctt tggcatggtt gattgcttca actgtttgtg gcatgacgcc
    71161 atcatctgca gcaacaacta agatcgtgat atctgtgata cttgctccac gtgcacgcat
    71221 acttgtaaag gccgcatgtc ctggtgtatc caagaaagtg attggtttac catcaatatc
    71281 gatctggtag gcaccgatat gctgtgtgat tccgccggct tcgccgcttg ttacacgtga
    71341 atggcgtaat gtatccaata aagttgtttt cccatggtct acgtgtccca taatcgttac
    71401 gactggcgga cgtgagacta atttatctgg atcgacttct tctgcctcga agaatttatc
    71461 gatatcagca atgtcaactt ggactttttc ttgtggttcc atgccatagt ccgtcgctaa
    71521 cagttcaatc gtatctttat ccagtgcttg gttttgattg accatgacac caagcataaa
    71581 taatttttta atgatttctg ctggctcacg atgaattttt ttcgcaatat ctgctacgtt
    71641 cataccttca gtatactcta atacatctgg caattcacgg aatttgcgtg gtggtacagc
    71701 tggtttagtt gattgttgct gtttgccttt tttacctttt ttattataac gattacggtt
    71761 attattatta aatttgccgc gattgttatt gtttggtttg ttgttattgt tagtacggtt
    71821 ttgattgccg ccttggctcg ttccttgacg attttggctg ctggtatttc ccgtattatt
    71881 ttggtttgtt gttggttttt ttccttgatt cacttgaccg ctcccttgac cgcgatcttg
    71941 ataactgcgg ttatttttat ttttttgttg attgttcgtt gtttcttttt tacgttgatc
    72001 gttcggctgt tgattggctg gttttctgct tgcttgttgt gcagcttgtt gtttcgtgct
    72061 tgggtttttg aacgcttgtt gcaatttctt ctcatcattg ctagtaatcg cacccatatg
    72121 gtttttcaca tcgatgccaa gttgttgtgc tttttccacg acgtctttac tagatttttt
    72181 gagttctttt gctaattcat agattctttt gttgcccatg caatcacctt cctaaccttc
    72241 aattagctcc ttggtcttct tcgcaaatcc ggcatccatt attccgaata ccttgcgagg
    72301 ttttccgatc atctgcgtga tttctgcttc agaaaatagc tcaaagcaag gaacttcata
    72361 atatgaactc ttatctttta tcttttttct tgtattctcg cttgcatcgg ttgccacaaa
    72421 caccaatttt gctttttgtt tgcggatttc agcaatggtc agttcttcac ccgtgattag
    72481 ttttcccgcg cgcatcgcta gaccgatgag attcatggct ttttgccgat taactgtatt
    72541 cattttccaa ataactcttt acgtgctttt tggtgagtga catagtcaag aagttcttga
    72601 taaaactcat ctgttaatgt tgtttcgagt actcgatcga gaattttttt atcccaagct
    72661 tgttgtactt cttccggctc aagtgagaca tacgctcctc gtccaggcat ttttccagtt
    72721 ggatcgatcg atacttcccc ttcttttgaa cgggtgattc ggaccatctc ttttttaggt
    72781 ttcatttcac ctgaaaccac ggatttgcgt aaaggaattt tcctttgttt catctctttg
    72841 cctccttact aaagttaagc ttctggtttt tcttcgaccg tttcattgtt gaatgcaatt
    72901 gtttcatatt catcgtctgt taaatctgac tgaacgattg cttcatcatg cagttcttct
    72961 gtttcttttt gttgttcttg attttcataa aattccgtca tgtcagattc tgatttgata
    73021 tcgattttat ggttagtcaa tttagcagct aaacgtgcgt tttgtccgcg tttaccgatt
    73081 gctagcgata attggtagtc tggaacgaca actgtgcagg cctttggatt tgtctcatcg
    73141 aagatcacat ccatgacttg tgcaggattc aatgcatttg caatgaatac agctggatct
    73201 tcattccatt cgacgatatc catgttttcg ccttttaatt cattgacgat tgcttgaact
    73261 cgttgtccct ttggcccgac acatgtaccg actgcatcga tatttggatc atttgagcga
    73321 actgccactt ttgaacgatc gccagcttca cgggcgatgc tgacaatttc aacgattcca
    73381 tcatagactt ctggtacttc ttgctcaaat aagcggcgca ataggtctgg atggctgcgg
    73441 ctaacaaata cttgcggacc tttagacgta ttttctactc gggaaacata aactttgatt
    73501 cgatcatgtg gttgataaaa ttcatttggc atttgatctt gtttagaaag aactgcctca
    73561 attttaccaa gattgacata aatataacgt ttatcctggc gttcgacgat tccttgcatg
    73621 atgtcttttt cataagcact gaattcgtta taaataatcg ttctttctgc ttcacgtaca
    73681 cgctgtaaaa taacttgttt agccgtttgc gcagcgatcc gcccaaaatc ttttggtgtt
    73741 acttcaaaac ggatcgtatc accgatctca tatgctggat tgattaaaag tgcatctttc
    73801 aatgagactt ccaactgtga atccatcact tcttccgtta cttcttttac cgcatagaca
    73861 tggatctttc cttttttctg atcaaattcc acttcgacgt tttgtgcttg gccatagtga
    73921 cgtttgtatg cagaaaccaa tgctgcttct aaagcatcga tcacgatttc ttttgagatc
    73981 cctttttcag cttctaaagc gtctaacgca tttaacattt ctttactcat tttttctgat
    74041 tcctctccgt gattaaaatt ggatagctaa gcgagctttt gcaatatttt ttcggtcaaa
    74101 agtcaattct ttttctcgtg tttttatgcg tattttcaat gtaagctgtt cagcatcaaa
    74161 tgattgaaga aatccttcat attgtttttc gccatctact ggttggtata aggagacatg
    74221 gacataatca ccaagtgcct tttcatagtc gctttctttt ttcaatggcc gctctgctcc
    74281 cggggaggat acctccagga aataagcttg aggaatcgga tctggatctg ctgcatcaag
    74341 tttttcactc agtttctcac tgacaaaggc gcattcttcg atatcgatac cgccttcttt
    74401 gtcaataaat actcgtaaga accagctttt tccttctttt acaaattcga cttcgacaag
    74461 ttcaaaattt tgttcatcta aaatcggtgt caccatttct gtgactgttt caacgacgct
    74521 actcaaaagt ttcgcctcct taaaaaatta agtgcgtaat tccattaaaa agagtgagcg
    74581 aaaaatccgc tcactcacag ttagtatcat tacctataag aactatacca tactctgctt
    74641 aaaattacaa gcagacagga aaacagatgc ttatagcata tcgaataacg ataattgatt
    74701 ttcatctggt agatctttca atacgccatt gtcgttcata tattcgatca atgtttttga
    74761 aactttaccg cgggtggcaa gatcttcttt ggataaaaat ggaccgtctt ttcttgcttc
    74821 aacgatttgt tttgccacgt tggttcccaa acttgggaca gctctaaatg gtgcgatcaa
    74881 cgtatcacct tcaataacaa agttaacggc atccgattta tacaaatcaa tcattccaaa
    74941 tttgaatcct cgttccagca tttcattggc taactccagc actgtcagtt gattcttttc
    75001 ttttacggaa gcatctaatc ctttgtccgt gatttctttc attgcttgtt tcacagcatc
    75061 ttttcctttg cacatggaga ctagatcaaa gtcgtctgca cgtacagaaa agtatgcaca
    75121 gtaatacaaa atagggaaat aaaccttgaa ataagcgaca cgaagagcca tcaatacgta
    75181 agctgcagca tgggctttcg gaaacatata tttgattttt gaacaagaat cgatatacca
    75241 gtcgggcaca ttattttctt tcatcgccga tagataggtt tctcgcaatt catcagggat
    75301 cttgttccat tgtcctttac gaacagtttc catgatttta aatgccatcc cgctatctaa
    75361 tccagcatgg atcaaataaa ccataatatc atcacgacag ccgattactt ccgccagtgt
    75421 cgcatctcct cgtcgaatca attcttccgc atttcctaac catacgtctg taccatgaga
    75481 tagtccggaa atttgcagta gttctgcaaa agttgtagga tgcgtttctt ctagcatccc
    75541 tcgaacaaaa cgagtgccga attctggaat acctaatgtc cctgttttgg aataaatttg
    75601 ttcctgactt actccaagta cttcaggacc ggcaaatatc cgcatcactt ccgggtcatc
    75661 cgtagggatc gtttgtggat cgatccctga taaatcttga agcatccgaa taacagttgg
    75721 gtcatcatgc cctagaatat ctaatttcaa tacattatcg tgaatcgagt gaaaatcaaa
    75781 atgagtcgtt ttccattccg aattttgatc gtctgctgga tattggatcg gcgtaaaatc
    75841 atagacatcc atataatcgg gaataacgat gatcccccct ggatgctggc cggttgtccg
    75901 tttgactcca gtagcgcctt ttgctaatct gtcgacttct gcacttcgaa actgcagatt
    75961 attgtccctt tcgtatcctt ttacatagcc atatgctgtt ttgtcggcga ctgtaccaat
    76021 cgttccggca cggtaaacat agtcttcgcc aaacaatact ttcgtatagt tatgggcttc
    76081 tgcttgataa tcacctgaga agttcaaatc aatatcgggc actttgtctc catggaatcc
    76141 taaaaatgtc tcaaatggaa tatcatgacc gtctttgttt aagcgtgcac cacattttgg
    76201 acattgtttt tctggcatgt caaatccaga accatacgta ccatcttcaa aaaactcgga
    76261 atattggcac tctggacaat aataatgagg ggctaacgga ttaacttcag tgattcctgt
    76321 catcgtcgca acaaagctag agccaacaga gccacgtgaa cctactagat agccatcttc
    76381 attactttta tgcactagtt tttgggcgat cagataaata accgagaagc cattaccatt
    76441 aatagaattc aactcttttt ttaatcgttt ttgaatgatc tcaggtaacg gatctccgta
    76501 catttgtttt gcttttgtgt aactcaattc tgatatttca tcttctgaac ctggaatctt
    76561 cggtgtataa agttcatctt tgactggaat cacttcttcg cagatatctg cgattttatt
    76621 cgtattttct actacgatct ctttcgctgt ttcttcccct aaaaagtgaa atgcagttag
    76681 catctcatcg gttgttcgga aatggacatc cggcaaacta tgacgattca acggattcgc
    76741 tccgcccata gaattgatca aaatttttcg gtaaatggca tcttcttcgt tcagataatg
    76801 tacattacct gttgcaacaa cgattttatc caaacttttt ccgatttcta ccaaattttg
    76861 gataatttct tccaaatcat gttcattttt taccaattct tgctcgatca aaggcgcata
    76921 gaccgctttt ggcataactt caatataatc gtagaatttt gctcggtttc ttgcctcttc
    76981 tacccctttt tgcatcatgg cttcgaatat ttctccctta tcacaagctg agccgatcaa
    77041 tagattttca cgcatctttt tcaattggga gcgtggtatt cgtgggacgc gttcgaagta
    77101 ttcgacattc gacattgaaa tcagtttgaa caaatctttc agtcctgcct gattttttgc
    77161 taaaatcgtt acatggaaag gtcgagccct tttgtaagaa tctccttctc cgatatgctc
    77221 atttagctga tcatgataaa gcatgttatg attgtccatt gcctctttca caaagatcca
    77281 tgctaagtga ccagttgctt cagcatcata gattgctcgg tgatgctgtt ccaagctgac
    77341 accaaatttt ttagataaca cacctaatcc gaaacgtttg aattgaggat acagatatct
    77401 agctaattcc aacgtatcaa tgactggatt ggccgcttca ggaataccat accttgcgta
    77461 gctagtattc aagaacccca tatcaaaagc cgcgttgtgg gctaccaaaa ttgtatcttt
    77521 tgaaaattca aggaacatcc gcaatacttc ttcttccgac tttgatcctc gaaccattcc
    77581 atccgtgata ccagtcagat ctaccgttgt tcgtgacaaa ggatgtcctg gatcgataaa
    77641 ttcatcaaag ctttcgatca catttccttt atacattttg actgcggcta gctcgatgat
    77701 cgtgtcatat actgcagaca atcctgtcgt ttccacgtca aatacgacat atgtggcttc
    77761 actcaatgct tcatgtgcat cattataagc aattgggaca ccatcatcta cgacattcgc
    77821 ttccacgccg tataagattt tcacacctgc tttttttcca gcactatgtg cttccggaaa
    77881 ggcttgcgca ccaccgtggt ctgtaatggc gatagctcgg tgtccccatt tccctgcttg
    77941 tgccacaaga tcagagatgc tgtttgttgc atccatcgta ctcatattgc tatgaacatg
    78001 aagctctact cgtttttccc cttcaggagc ataatctttg cgaggtgtat gtttgacttc
    78061 tatgatatct tgcgcattca tgaccaaatc acggacaaac gtatcttctt gaatacttcc
    78121 tcgtaccttt aaccagctac cgacactgat cgcatcaaat acttgttcat ctttttcgcc
    78181 gttcgagaat tttttgacga taaatgatga agtataatct gtgattttca aagtcaagat
    78241 cttgcgtttt gaacgtagtt ctctgacttc tttgtcgaat acgtacccct caagtgtgac
    78301 tcttcgttct tcttcaacga tactgatcat tggtgtcgtt ggttcatcgg ctggaatatt
    78361 tcgtcctagc tggatgtgga tgggtccttc aagagctggc gattgctctt ttctttcctt
    78421 tttcttttgt tcgtggacaa ctagactttc agctgcttgc ttcataaagg cttctgcctg
    78481 ttcttgtttg cgttcttcaa aaagtttcaa tactcgttcc gcttgctgct catccacttc
    78541 tggttcgata cgaaattttg ggaatccgta actgacgaac aactcttcta ctaatggcaa
    78601 gtattgttgc ttcaaataag aaatagctcc tgtactgtcg attggcaaga tgactttacg
    78661 atcttttatc acaggtacct gcgttttcaa tacttgctgt gctagtggtg tatcgcattg
    78721 ctgattttcc aaagcttggg cccagtaatc ttgcaagagc tgttcatcga atgtctggtc
    78781 atctgctaag atattcagtt tgacttgtgc aatatcttta aaagcgatag tcagatgctg
    78841 agtcaatgac cgatatagca taataggcaa aattttggaa aaatgcagcg taaattccca
    78901 taaacgcgat ttacgatgga ccactacact atccatttca ccagcagtaa gcagtggatg
    78961 atttttttct gcttcctcta gttggatttg ttccaacagt ttttcaaata aatctcgttt
    79021 ttctgacaaa gatatacgcc ctttctgatg agaaacaatg caattgatcg catcttatcc
    79081 tcttcttttt cagtaccttt tagtatactc gttttttctg agttttacat taaaaaattg
    79141 gaactgcgat tcaaatcgca gttccaattt taaaagcgaa tcatcagatt gtcaaaaaca
    79201 gctgattcag ctatttttat tttctgtgtt ttaacgctta ttattcgcct tggttcaaga
    79261 ggattggtaa agtattcacc aattcttctt tacgtacttc aaccatttcg ccagttttct
    79321 tgattttcac ttctacgatt ccatccactg cttttttacc gacagtgatt ctgattggac
    79381 agccaatcaa atcagaatcc gcgaatttca ctcctgcgcg ttcatttctg tcatcaacca
    79441 gtacttcata gccagctttt gtcatcgctt cttctagttc attcgtcagg tttgtttggt
    79501 attcgtcttt tagattcatt tggacgatat gcaaatcaaa tggcgcaatt ccttttggcc
    79561 agttgattcc ttgttcatct gaatgttgtt ctacgattgc tgataataaa cgacttacac
    79621 cgataccata acagcccata atcacaaatt tttctcgtcc attttcgtct agtacagttg
    79681 ctcccataga ttcactgtaa cgagtgccga ttttgaagat atgtccgatt tcgattcctc
    79741 gagtaaaggc aagaacacca ttgttgtctg gtgaaggatc tccttcttgt acaaaacgaa
    79801 gatcttcata agaaagtaca gtgaaatcgc gttctggatt cacattttta tagtggaatc
    79861 ctgtttcgtt cgctccagta atggcattcg ctaaatcttg gacataacgg tctgcatata
    79921 cttttacgtc atctgaaaca ccgactggtc cgacagaacc aaactcagca cctagatatt
    79981 tttgtgcttc ttcttctgtt gcttcttcta aaaagtcagc agataaaaag tttttcagtt
    80041 ttacgtcatt gacttcatgg tctccgcgta ccaaaacaag gacaggttgt tcatccgcaa
    80101 tgaacaatac agacttgatg attttttgag gttcaacaga aaagaaatct gctacttcgt
    80161 caattgattt tacgttaggt gtagctactt tctccaattc aagctgtgtt tcatgcgatt
    80221 tttttgatac atagtagctt gtagccatct ccaagtttgc agcataatca ctttcagtcg
    80281 aataacagat cgtatcctcc ccgatttctg agatcgccat gaattctttt gagtctttcc
    80341 cgcccattgc gccaccgtct ccgataatcg agcgaaattc taagccacaa cgcttgaata
    80401 cttcggtgta ggctttttcg taatctttat atgtctcgtc caaactttct tccgttgcat
    80461 ggaaagaata cgcatctttc atgataaact ctcttccgcg aagcaaaccg aagcgaggtc
    80521 gtttttcgtc acgatattta ggttggattt gataaagatt taaaggtaat ttcttatatg
    80581 aattgatttc attacgcatc aaatcagtaa aagtttcttc gtgagttggt ccaaggatca
    80641 tttttcgatc attgcggtct ttgaaacgat acaagtttgg tccatatgtt tcgtaacgcc
    80701 cggattcttc ccaaagttct gctggcaaga tggcaggcat cagcatttct accgctccga
    80761 ttttttcaaa ttcttcccgc ataatgcgtt tcagtttttc caatacacga tttgctaatg
    80821 gcagatatga ataaataccc gctgatactt ggcggatata tccagctctt agcaagattt
    80881 gatggcttaa tacttctgca tcatttggaa cttcgcgtaa tgttggaatc aacatttttg
    80941 attgtctcat tctatatact cctttatttc ctcaaaatag ttatcgtttg ttattatacc
    81001 ctatttgtca actttttcta gaaaaagaat cgttgaatat cgttccatgt aactagcacc
    81061 atcaacaaca ttaaaaatcc aaagccagct aatgtcaata ttccttcttt ttcttgactt
    81121 aatggtttcc cgcgaatccc ttcaaaaata ttcaagacta atttcccgcc atctaaggca
    81181 ggaatcggaa gcagattgac gattccgaga ttcattgaaa gaagcgccat caaactaata
    81241 acagttgtta caccttgatt tgctgcttct gaagacaatt ggtacatcat gacaggtccg
    81301 cctaatttat ctaaactgaa acctgtaaat agtgatccta aggctttgaa aatttccaat
    81361 gaaccgctga aagcttgacg cgtccctcca atgatcttat ccataaaacc tgtattcatt
    81421 ggggctttta taccaagttg gccaactttt tcgccatttg actctacaga tttcggtgtc
    81481 acgtcgacag attgcacctg accttctcgt tcgatcttaa agtctaatgt tttatccgga
    81541 tttttcgtaa tgactgttgt cagatcattc catgaatgga tttcttttcc gtccacactg
    81601 actacctcat cattttcttt taagcctgct tctgccgcag ctccattagg catgatctct
    81661 cctacgcgat tagtgttcgt cacttgaaca ccaccttgca taaatgccag aatgatgaat
    81721 aacaggattg ccaaaataaa gttattcatg ggtccagcaa agttggtcag catacgctgc
    81781 cacaatttag ccgattggaa ctgtacgtct tttggcgcaa ttctgatttc tgttccgtcg
    81841 ttttcaataa tcgtcgcatc gtgatcaaca gggtaggtta ctacttctgt ttcgtctcca
    81901 ttcacataac cagtgatagt cagctcatct tctaaatcat aacggctcaa ttccatcggg
    81961 atagcatttg tcaattggat tttcttactt aaatttatct tctctacgat gccgtcagaa
    82021 tttagtaaaa gagaaagagg cattcctggt gccatttctg tttcatcatc cccattgcct
    82081 gccattcgaa cataaccgcc aataggtaat aggcgaagcg tatatgttgt cccgtctttt
    82141 gcttgatgcc cataaatttt cggacccata ccgatagcaa attcgcgaac gaggattcct
    82201 gatcgtttcg caaagaagaa atgaccaaac tcatgaacaa tcactaatat accaaaaacg
    82261 atgataaatg tcagaatcgt tttcatagct tttttctcct ttacttgttt tttgtgtttt
    82321 ttataaaaca acgataaaac actataattt taccatagta taccaaagac accaatagta
    82381 tcaatataat gaaaaataaa aacctgcgtc ttttatgaaa ttcacaaaga aacgcaggta
    82441 tacttactaa ataatgccaa ataaatgcat gataggaaat acaaacagca aactgtcgaa
    82501 acggtctaag attccaccat ggcctggtaa gatatttccc gagtctttca catcataatg
    82561 acgtttgatt gcagattcga ccaaatcacc aaattgtccg actgctgaaa aaataatcgt
    82621 catcagaagc atgacaaaca taccatgatt aaatagttct tttgctgggt atagcaataa
    82681 ataaagaaat gcgactacaa cagcactacc aataccaccg agcgcacctt caatcgtttt
    82741 gttgggcgaa atatcaggac ttaacttatg ctgaccataa cgtcgaccaa ccatatatgc
    82801 tccgatatca gttgcccaaa caataaatag accaaatatc aaaacagcca agctttctgt
    82861 tcgtgcattg acaaaattct ggaaacctat tcccacatac aagctgacaa gcacaggaaa
    82921 acctgcttca tcaatcgtat acgtattttt agaaataact gatgttccta aaagaatcat
    82981 aactataaga taaaataaca taaatgtact tacattctct ggaagaaaga aaaaccatct
    83041 ttcttttggc aaaacaagta acactgcacc aacggcggat aaaactcctt caaaacttaa
    83101 gagtgtcaat cctttcatcc gaaacagctc gtaaactcct attactgcta agattgctgc
    83161 tgtaagctca accgctatgc ctccgatcca tataatcgga ataaacaaga ctagcgccac
    83221 ggctgctgtg accacacgtt gtttcatgac tgatcccctt tctcatcttc tgtttttttt
    83281 acaccgccga atcgacggtc tcgattttga taagaggcga ttgcttcttc aagatgcgca
    83341 ccatcaaaat caggccaaag cgcttttgta aaatacagct cactatatgc gatctgccat
    83401 aacagaaaat tactaattcg ctcttctcca cttgtacgga tcatcagctc aggatcttgt
    83461 aactctttag gcaagaaacc tgtcattaaa tgcttagcaa tcaattcatc atcgatttct
    83521 tctgcgtgta tttctccttt tgctacttct tcggcaattt cttggacagc agtcacgatc
    83581 tctgctctgc ttccataatt caaagcaaaa ttcaatacca ttccagtatt gttttttgtt
    83641 tgctcaattg cacgtcttac agcatcttgc gtatgttctg gcaatacgtt ttcataaccc
    83701 atgacatgaa ctttgacatt ttctttaatc aattctggta cgaacgtatc aaagaagtcg
    83761 acaggtagtt gcatgagaaa acttacttca tcttttggtc gcttccagtt ttcagtcgaa
    83821 aaggcataaa gcgtcaacac tttcactcca agccttgatg ctttttttgt gactttcttt
    83881 actgtttcca tgccttcttt atggccagca actcgtggca aacgacggtt ttgcgcccaa
    83941 cgaccattgc cgtccatgat gatggcaatg tgctgaggaa ttggtccatc ggtattaaat
    84001 tgaaattcgc ttttttcttg aatatatttg tttttttgcg gaaaaaaacg taacattctt
    84061 tttcctccta tacttaaaag attcccacta tcttaagtat tatagcaata tctaactgtt
    84121 tttcctatga aatcattgtt tttttattta aaaactgaat aattttttct ttttttaatt
    84181 tttaaataaa agaaatataa ataaaaacag aggaagcgga atgatccgcc cctctgtttt
    84241 tatgatttta ttaaacttcc aataattctt tttctttatc agcagcgatc ttatctactt
    84301 ctttgatgct gttatctgtc aatgtttgta cgtctttttc taatccgcgc aaatcatctt
    84361 cggtaatatc accatttttt tgttgttttt tatattcatc gatcgcatca cgacggatgt
    84421 tacgaatcgc gatttttgca ttttctgctt cttttttaac atctttagct aattcttttc
    84481 tgcgttcttc tgtcagttgc gggataacta agcgaatgac atttccatca ttggttggac
    84541 tgattccgat atcacttgcc ataatagctt tttcaacatc ttgaagaatg ctcttgtcaa
    84601 aaggtgtgat cattaaaaca cgtgcttctg gaatttggat tgatgccatt tggttcaatg
    84661 gtgttggcgc accgtagtag ttcacagtaa tacggtccaa aaggctagcg ttcgcacggc
    84721 ctgcgcggat ttgcccaagt tcacgttgaa gattttgtgc tgcttttttc attttttctt
    84781 ttgcttctgt cataattgca tctgccattt ttatttcccc cttacagttg ttccgatatt
    84841 ttcgcctaag attgcacggc gaatatttcc gtgttcattt aaattgaaga caagcagtgg
    84901 aatatcatta tccatgctta gtgaacttgc agttgaatcc atgacttgta atcctttggc
    84961 aataacttcc agatgagtca gttcttcaaa ttttactgca tttgcatcta ctttcggatc
    85021 agcagaataa acaccgtcta cattgttttt agccatcagg ataacatctg cgccgatttc
    85081 tgccgcgcgt aatgctgctg ttgtgtctgt cgagaagtac gggttgccgg taccgcctgc
    85141 aaagataacg atccgtcctt tttctaaatg acgttctgct ttacggcgaa tatatggctc
    85201 tgcgatttga cgcatttcaa tcgaagtttg cacgcgtgtc ggtacaccca cgttttccaa
    85261 cgtatcctgt aaagctaagg cattcataac tgtagctaac atacccatgt aatcagcttg
    85321 agcacgttcc atgcccattt gtgctccgat ttgtccgcgc cagatatttc cgccgcccac
    85381 aacgattgcc atttcaacgc ccagctcgtg aacttctttg atttcttgga tgatttcttt
    85441 gattactggt ggtttgattc caaatcctgc gtccccagct aaagcttctc cactcaattt
    85501 taagactaca cgctgatatt tcggtgtgac catgttcatt cctccaatat tttctattgc
    85561 cattttacca tacttagatg atttcgacac tctaagactg gtttttcttg ttttgcttaa
    85621 aaaaagggag cgcacaaacc gtgcgttccc gtctgttatt caacagaatt attttttcac
    85681 ttggctcata acttcttcta caaagttatc ttcgcgtttt tcgatacctt cgccaacttc
    85741 gaaacgtacg aatgttttaa cagttgcgcc ttttgatgca acgtattttt caacagtcat
    85801 atcaggatct ttaacgaatg gttggtccac caaagcgatt tctgctttga atttcttcaa
    85861 gcgtccttct accatttttt caacgatatt cgctggtttg ccttcgttca atgcttgttc
    85921 tgtaagaaca gttttttcat gttctaattc agcttctgga atttgtgatt cgtttacata
    85981 acgaggattg atagctgcta cgtgcatagc tacgtctctt gcaactgttt cgtcagttgt
    86041 tccatctaga acagtcaata cggcaatacg tccgcccata tgcaagtatc caccaaatgc
    86101 agcattgtcg tctttttcta caacttcaaa gcgacggaag ctgatttttt ctccgataac
    86161 ttgagttgct tcgatcaagt cagattcaat tgtaccttta tctgttttga ttttcattgc
    86221 agcttccatg tctgctggtt tgttttcagc aacaagttct gcaatttctt ttactaaatc
    86281 ttggaacatt tcgtttttag aaacaaagtc tgtttctgag tttacttcaa cgattgctgc
    86341 agtgttacct ttcacagcaa ctgaagccaa tccttcagct gcaatgcggt catttttctt
    86401 cgcagccttt gccattcctt tttcacgtaa aagatcaact gctttttcca tgtcgccttc
    86461 tacttcaact aatgcttttt tcgcatccat cattcctacg ccagtcattt cgcgtagttc
    86521 ttttaccatt ttagctgtaa cgtctgccat gtttaactcc tcctgtgtgt ttttcttttt
    86581 aaaaaaagct gcttcaaagg agagtgaggc ttgtcgccca gcctttgaaa cagctccatc
    86641 attcaaaatt attctgctga agaattgtcg ccttcaacaa catctacgat ttcttcgatt
    86701 gatgttgctg tgttttcttc tgtgaaatct tcttcaacta cttgatcttc accttggttt
    86761 ccttcgatga aagcatcagc catttttgaa gtaatcaatt taacggcacg aattgcatcg
    86821 tcgtttgaag ggattactac gtcgatttca tctggatcgc agtttgtatc aaccatagct
    86881 acgattggga tatttaattt gtgtgcttct tgaacagcaa tacgttcttt acgtgggtca
    86941 acgatgtaca ttacatctgg gattcttggc atatcagcga taccgcctaa gaatttttca
    87001 agacgttcac gttctttgtt caaaccagca acttcttttt taggtagaac ttcaaaagtt
    87061 ccatcttctt ccattgcatt gatttgtttc aaacggctga tacgtttttg gatagtatcc
    87121 cagtttgtca atgttccgcc taaccaacga tggttaacga agtattgtcc tgcacgagtt
    87181 gcttcttctt tgattgcttc ttgtgcttgt ttttttgtac ctacgaataa tgctacgccg
    87241 ccttcttcag caacgctctt catgtaatca taagctgcat ctactaattt aactgttttt
    87301 tgcaagtcaa tgatgtagat tccgtttctt tctgtgaaga tatatttctt catttttgga
    87361 ttccagcgac gagtttggtg accaaagtgt acgccggctt ctagtaattg tttcatagaa
    87421 attactgcca tgtttgtttc ctccgatttg gttttatttt tcctcttctt atcttctacc
    87481 ttgccggcaa actttttcaa gcacctaccg acaatccaat aagaatgtgg atttgctgat
    87541 gcataaagca ccctcagcta ttatacagac aaaagatccg tatcgcaaga gcaaatatac
    87601 ttttctgctc aacattcaat agtttacctg aaagataaaa agaattcaag aaaaacagta
    87661 gatttctctt tgtttcttta ttatcctttt tccataaaat aattttaggt ataaaagacg
    87721 aatattattg ggcaatcctt cttttttttg ttatgataca tgtgaaatct ttcgtaaagg
    87781 agaaagaaaa tgcgcaaagc tcaaagacat ttgctgatta aacaagtcat tgaagaattc
    87841 ccgatccgta cgcaagaaga actattaaac aaacttgggc attatggcgt taccgccacg
    87901 caggcaacga tttctcgaga tatccgtgat ctaaaaatcg tgaaggcacc tgatgaaaat
    87961 ggcgtttccc gcttcgtatt gtttcgcgaa aaaggaactc ctgagactag gactgaggaa
    88021 gaggatcggc tggttcaaat gattgaagac attgtattga aagtcgaacg agtccacttt
    88081 ttgacgatcg tcaatacctt gccagacaat gctcatttat ttgcatctgt tttagatgag
    88141 atcaaacctc cctctattgt cagtacaatt gctggattcg atacgatcat ggtcatctcg
    88201 gaaaatgagg aggacgcaaa acgagtagaa gaatttcttc accatccaac tgaagtatca
    88261 cttttttaat cagagcacgt attcctaata tggaatgcgt gtttttttat tttcaatatt
    88321 ttccttattg aataaacctt tacactcttt acaaaaatac atcatttttt attcaaattt
    88381 ttcaacacct tgattgaatc acaataatca tcatttatat tggatgttaa caagagcagc
    88441 ttcttgctct ttgtgtattt caaaaaagaa atgaaaggaa atcatatgta taaattatta
    88501 acttctggac cattgacgac ttctgaaaca gtgaaaaatg ctatgctgat cgatcattgt
    88561 acttgggatc aagaatacaa agaaattaca caatggataa gaaaaaaatt attggatctt
    88621 gctcaagtat cggaaggaat atacacaacg gtcttaatgc aaggtagcag ctccttcggg
    88681 gtagaatcgg tattaagttc tgtgatcagg ccagaagata ctgtactgat ttgttcaaac
    88741 ggcgcatata gacaacgaat gatcaacatg tgcgaatgtc tgaaactgaa ctataccgtt
    88801 tatgaggtat cggaacatca aatcctccaa gctcatgtga ttacacagct gattgaagag
    88861 aatccgtcta tctccgcact agcaatggtc catagcgaga ctacttccgg tattttgaat
    88921 aatttggaag agattgctgc tgtcacacaa gaaagagatc ttttgtttat agtggacgcg
    88981 atgtcaagct ttggtgggat accgatttgt gtagccgaac tagggattga ttttttgatt
    89041 tccagctcaa acaaatgtat tcaaggtgtt ccaggctttt cttttgtact tgctaataaa
    89101 gcggaactgg aaaaacgaaa aaatgttagc cgaagtttgt cacttgatct atatgaccag
    89161 taccgcgtga tggaaaacga gaatggcaaa tggcgtttca cttcccctac ccatacggtt
    89221 ttggcttttc aacaagcgct gaaggaacta gaggcagaag gaggaatcga aactcgatat
    89281 tcacgttatc tcgccaataa tcatgtgcta cgacaaaaaa tgacagagat ggggttccag
    89341 cctttcattc aagaatatca ggggccattc atcacctctt ttctttaccc taaggactgg
    89401 cgatttgatt ttaatcattt ttatcagtat ttaaagcaaa atggatttgt gatctatccc
    89461 gggaaaatca gcgatcatga atgttttcgt atcggaaata ttggcgagat ctatccggaa
    89521 gatattttgg aactgacagc aattatcaaa gactataagg agaacgttaa tgattaaaac
    89581 tgtaattttt gattgggcag gaacaactgt ggactttggc tgtatggctc ctgtccacgc
    89641 ttttagaaat gcttttctag aaaaaggaat ccaactgact gacaaagaaa tccgctaacc
    89701 gatgggaaaa ttaaaatggg atcatatcca acagcttctt tccctccctt ctgtcaaaaa
    89761 acaatggata gctatttatg gacaactacc tcaggaaaaa gaggtggagg aattgtatca
    89821 acaatttgaa cattatctgt ttaaagattt ggtcaagcat tctaccttga aacccgacac
    89881 attggaaacg atcgaacggt tgagaaacgc tgggatcaat attggttcca cgaatggatt
    89941 taatgctcct atgatgacaa tcgtagcaga aaccgcaaaa aaagaaaggt attcaccaga
    90001 cttcatggca acttttgaag acgtcgaagg gtatggtcga ccgtttcctt atatgatcca
    90061 taaaaacatg cagtacttca aaaacaagtc ggttgatgaa gtaatcaaag tcggagatac
    90121 ggtctcagat atccaggaag ggaaaaatgc cggagtgttg acagtaggtg taattgaagg
    90181 tagttcgcta atggggattt cttatgatga gtaccaaaaa ttagagatgg ggaaaaagat
    90241 cgtttaaaac agtctgttgc tcttagattc caacaagccg gcgctgatat ttgtgtaaac
    90301 aatttaaaag agttaacaga atacattttg tacgctgaca tgaatccaga atgactttta
    90361 tacaaaataa gaggttgtga aaaagctgtc ctgtatcaag taataaaaac agccaagcaa
    90421 aaatagctcc tcatattttt cgtttggtta ggcttattac cgcagatgca agcttttgaa
    90481 caccgtttat tcgaaaaaaa aaagggagct gtgacacgac ttttgtcaca gtccccttat
    90541 ttgcaaacaa acagtgttta agagacaacc tctccactaa acggtgttca ttcagctgac
    90601 tctcggtatt tgctcaaaaa acgataaaat ttgaaaagct attttctctt ttgtttctct
    90661 aatactcgga tcagaacgct gatttcacat tctctttttc ttacatctta tctggtgcat
    90721 gaagtcctag caaacgaagg tcttctttca ataatacagt cactgcataa actagagcta
    90781 agcgtgcttc tttttgttca tcatcagcta aaatcttcgt atgagcatag tatttgttga
    90841 atgcttgtgc taatttgatt gcatgtttcg caatcactga cggttcgtat ttttccccag
    90901 cagacaagac cgtttcaggg tatttttgaa ctaatttaac cacttcccag ctggtatcgt
    90961 cattcaatgc atagtctgct gtttctgaag ggacaaatcc tgctttttcc aacaggctga
    91021 ctgcacgagc atgtgtatat tgcacataag gtccagtttc tccttcaaat cgaacaactt
    91081 cttccaggtt aaagtcaaat gtattcagtc gatcgttttt caaatcgtgg aaaatgactg
    91141 ccccaacccc aacttgttta gctacagcat ctttgttttc caaatcaggg tttttctcgc
    91201 tgatttgttc tttagcagat tggattgctt catttaatac ttcttctaat aagacgatct
    91261 ttcctttacg agttgataat tttttaccac cttgcgtgat caaaccaaat ggaatatggt
    91321 gcatgtcgtc agaccagtca aagcccattt ccttcaagac agctttcaac tgtttaaaat
    91381 gatagctttg ttcattccct actacatata gagattgttt gaagtcgtaa gtacgtttac
    91441 ggtacaatgc agcagctaag tcacgtgtaa tgtatagtgt cgcaccgtct gacttcttaa
    91501 tcaacgctgg attcaggtca taagcagata ggtcaacgat ctctgcacct ttatcctcgt
    91561 tcagcaaatg tttttcttct aaaagtttga cgatttcatc catcttgtca ttgtagaaag
    91621 cttcaccgtt caacgaatcg aaacgtactt ccagcagatc atagatttta ttgaattctt
    91681 tcatcgattc atcacggaac cattgccata attgaatagc ctctttatcg ccttcttcca
    91741 gacgtttgaa ccaagcacga gcttcttcat ttaattctgg ttctgtttca gctacttcat
    91801 ggaattggac gtataaacga agcaattcat tgattggttc tgctttaaca gcttcttctg
    91861 taccccattt tttgtaagcg acgatcagtt ttccaaactg tgttccccag tcacctaaat
    91921 ggttgatgcg gattggctga taaccgattt tttccataat gaaaccgatc gaattaccga
    91981 taactgtcga acgcaaatgt cccattgaga ttggtttggc aatattagga gaagacatgt
    92041 cgattggtac tgttccttga ttcccgatgt tgctatcccc ataatgttct ttttctttca
    92101 ctactgtttg caaaactttt ttgctgataa gttctttatt catgaaaaag ttcaagtaag
    92161 gtccgacaac ttcgattttt tcaaagttgg cagaatcgat tttttctgct aaatctgcag
    92221 cgatttgctg tggcgctttt cggtaaactt ttgctaatga aaaggctgga aatgcaacat
    92281 ctccgtgttc agctgatttt ggattttcta gtaattgctc gacttgttcc agtgttaaat
    92341 catctttgac agcgtcatag acagcttttg cgacaagatc tttattattc atctttattc
    92401 ctcctaaagt gttcccttga ttgttaaaca aaaaaaatct ctagcgacgg catacttagt
    92461 atgccatcac tagagacgag atttcccgcg gtaccactcc aattgtccta aaaaaggacc
    92521 agctccatct gatatcggta gacgaccgtc tgtttaaaac agaattctcc aagtgcgctt
    92581 cgttgtatct tcttcattcg gcttccacca cttccgaatt cgctagccaa gaatgataca
    92641 agtactctct tgttcaacaa atcttagtct tattaaactt tcttgaatta tatcagaaaa
    92701 aaaaacgaaa ggctagtcgt ttcataaaaa aacaatccag atggcctaaa ggagaagaaa
    92761 taccacctgg atagctataa atcatttcgt aaatacgaaa gacttaacaa attaatcagc
    92821 tacgataatc gttccttctt cagaagctaa aagattctcg atattttcta aagaagtgat
    92881 gattgcctta gcgtttggtt ttgcttcaac aaatgcaata gctgcttcta ctttcggaag
    92941 catgcttcct ggagcgaatt gcttttcatc aatgtattgt ttcatttctg aaacagtaac
    93001 agtttctaat ttcttttgat ctggtttttg gtaattgaca tacacattgt ctactcctgt
    93061 caatacgatc agcaaatccg catcgatgat ttcggctaat ttttctgaag caaaatcttt
    93121 atcgattacg gcttctcgtc cttctaatcc agtagctgtt tctacaacag gaatcccacc
    93181 gccaccaaca gagactgtga taactccttg atcgaccagc gtttcgatga cacgtgcttc
    93241 tttaatcgag atgggtttag gggaagcgac tacttttctc catccacgtc cagcatcttc
    93301 tttgaatgtc acagtggagt cagcattcat ttgttctttg gcttcttctt ccgtgtagaa
    93361 tggaccgact ggtttacttg gatttttgaa tgaaggatca ttttcatcca caataacttg
    93421 agtgactaaa gaaaccacat ctttatcgat ccctttttcc ttcagtactt cgcccatggc
    93481 gttttgtaac cagtaaccga tagatccttc tgtcattgca acacatgtat ctaaaggcat
    93541 tgccggtgtt ttctcagaat cagcagcttg ctgctgaatc aataggttac cgacttgcgg
    93601 accatttccg tgggagatga tcaattcatc tccttgttcg ataaatttca ctaaatactt
    93661 tgctgtttcc attaacgctt cttgttgggc ttttgcactt gcatccgtag acaagatggc
    93721 attgccccct aaagcgacaa ctacttttcg tttggccatt tcattcgtcc tttcttcagt
    93781 tctaccgaat tttctagata acaaaacgag ccagcgtttt gtgattttcc ctcaatgctg
    93841 actcgttttt tcgtgagatg aatgtggtta tgcttaaacg cgagggataa acaagttacc
    93901 taatgttgct gccatgatcg ctttgattga gtgcatacga ttttctgctt ggtcaaattg
    93961 acgagcatat ttgctgcgga agacttcatc tgttacttcc atttcagtga tgccaaagcg
    94021 ttctttcatt tgttcaccgt aaacagtgtt tgtatcatgg aaagctggca agcagtgcaa
    94081 gaagatcaaa cgatctgtgt tgtgtgtttt ttctaccatt tccatattga tttggtaagg
    94141 tttcaacaat ttgatacgtt cttcgaattt atcttcttca cccattgata cccatacatc
    94201 agaataaagg acgtctgctc cgtctacacc tttatcaaca tcgtcggtaa tcatcaattg
    94261 tgcaccggat ttttcagcaa agccttctgc cattttgacg atttcttctt caggttgtaa
    94321 ttcttttggt gcaacgatac gcatattcgc tcctaaaatt gcacctgtga ctaataaaga
    94381 gttagccata ttgtttcgac catctccgca gtaagcaaca gtgatacctt ctactgttcc
    94441 aaagttttct tggatagtta aaaagtcagc gatcatttgt gttggatgcc attcatcagt
    94501 caagccattc caaactggaa caccagagaa ttctgctagt tcctctacca ttttttgact
    94561 gaatccacgg aattcgattc catcaaacat acgacctagt actttagctg tatcttctgt
    94621 ggattctttt ttacctaatt ggatatcatt tgcacctaga tattcaggat gtgcacctag
    94681 atcgatcgct gcagtagtaa atgcagaacg agtacgtgta gatgtttttt caaataaaag
    94741 cgcaatattt tttccttcta gatagtgatg tgggatacca cgttttttca agtctttcaa
    94801 gtgttctgaa aaatcgatca aatattgtaa ttcttctttt gtaaagtctt tttctgctaa
    94861 taagcttctt ccttggaata ctgattcttt catattaaac attctccttt agattgtttt
    94921 tatttaagat taaagaggaa atcccgacgg cagctgacag taagaccgcc gtcaggaaac
    94981 aaattacttc aagtcttcac ggacaagtgg ttggctcatg cagcgtggac caccacggcc
    95041 tcgtgacaat tcacttgaat tgatttctaa cactttgatg ccatagctac gaagcaattc
    95101 gttcgataca taatttcggt tataagtgac tacaacacct ggagcgattg ccaatgtgtt
    95161 tgatccatca ttccattgtt ctcgaggtgc aacgatctca tctccattac cagttgggat
    95221 cagtacaaga tcatctaatc caagagcagc tttcatcgtt tcgtgtaagt tatctgaatg
    95281 agtaatcttg atatcatcac catctggttc gattgtaaag acatccatct taccgtcttt
    95341 actttgaatt gctggatgga tagtgaattt atcgtgatct accattgtaa atacggtatc
    95401 caaatgcatc attgcacggt tgtttggaat tttgattgct aacacttttt caaatcctga
    95461 attttttgcg aataggtggc gtgctaattt ttctaaagct ttcgcattag ttcgttgaga
    95521 aatcccaaca gctactactt tatcgcttaa gatcaattcg tctccgcctt cgatatgatc
    95581 tggattttca cgatccaacc atacttcgat tcctttattt gcaaatcttg gatgatgttt
    95641 caaaatatat tctgtaaaca tcgattcacg acgacgtgct tcaaaagtca tcttattgac
    95701 tgtcatccca tttcccattg atgcggaagg gtcgcgtgta aagtacaagt ttggcattgg
    95761 gtccatgtaa aatggatagt catcgtctgc tgacagatcg tatagactgc tagaacgtac
    95821 ttcaatatct tttgtacgaa ccccagccat gattttatct accatttctt gcgtttccat
    95881 tgatagaagg aactcatgaa gaccctctct tacagcattc gatgcaatat gagattcatc
    95941 caacatttta ttcaagaatt gttctttgac attgcctgcg tcaatcgctt ctgccgctaa
    96001 tttttccaag taaagagtct cgacgccttc attttgcaat gtcttcgcaa agttgtcatg
    96061 ttcttcttga gcaatcggaa gatatggaat atcatcgaac aacagacgat ccataatatc
    96121 tggtgtcaaa ttttccactt cttgtccagg ccgtttcagt aaaactgtct ttaatttccc
    96181 tatttcagag aaaacgtgaa taggtttatc catgttgtgt tgcctccttc tttttgatta
    96241 catgtatagg atatcctcct tttgtaatca ctttcataat tttgtctcat tcaaaatgag
    96301 acattcctca cattaatatt cgataattaa ataattaaac gtttttctat ttttaagcgt
    96361 aatttattca ttttttattc tgtatacact ttcaaaaaaa tatttattca ttgaaaaaat
    96421 ttttttgaat aaattaaaaa aataaattat attatcgttg ttagcgttta ctatatgtat
    96481 tattgttgtt ttttatacac aaatcattcg cttcaaaaca aattattcaa taccattgta
    96541 tattttttac ataataacaa attatatttg taaagtatta aaacttgttt ctaatgttgg
    96601 tatgttaaaa ctttacaaat tctttaaaaa aagtgacaat aaatatagtg aacaataagg
    96661 agaggacttt ttaatgcgtg ttaataaaat cgattttcac ttttcaaaac tcagatatca
    96721 acctgatttt gaacatttct cggatgaaga gttccaacag atcaaggaac atactgttct
    96781 tcgttcttat aaaaaaggac agatcctttt cgacgatggt gatcccagac aacggttgta
    96841 tatcttgacc aaaggactcg ttcgtttaga acgttatgat gaaagtgcaa cttattacta
    96901 ctatgactat gtgaatacaa ataacctttt tcctatgtca ggaatgtttg gagaagagac
    96961 ctacacttat acagctcaag cgatgactga tattgaaaca ttctaccttc ctgtttccta
    97021 ctatgaaaaa ttagcacgaa aaaatcccga acagttgatc tatatgatac aaaaaatttc
    97081 taaagtagtt gaaatacatg aattgcgtat ccaaatcgga ttgacctcta gcgcctttga
    97141 ccgggtaaaa caaaatttat tcattttgaa agaagaattg ggcgtaccaa caaaagatgg
    97201 tcatatcacc attccttatc cgatcacctt aaaagaatta gcagtgaata gcggcacgac
    97261 acgtgaaact gctggacaag taatcaaaca actacgtgat tccgggctgt tagattatga
    97321 caaaaagcgt tttactttct gtaagacagc tactactcca gctatgagag aataacgcga
    97381 acaaaaataa gcagtgaccc tgataaatat cagggtcact gcttattttc ctccctaaaa
    97441 cttctgaaag atccggcagt tttagatcac tggacaagac tcaaagattt tctatgtgtg
    97501 tttcagttat gtaatattca ctgtttgcaa aaaatactgt tagattaact agatgaagcg
    97561 tcttgtcctc atccgatcta gattattcga tattcctcga caataaacga ttactcagtg
    97621 agggcaatca gaggaacgga taatgataaa taagctgtaa aaaatagcaa aataacaata
    97681 atgattaaaa gtatgtaaaa aatagggctt tgacaaaaac gtgtcacagc cctatttcga
    97741 ttaaacggtg tgtacctgtc aactcttcgg tcacaagtca taatgttcat aaacatgagg
    97801 agctgttttt tgaaattgtt ccttgtgaat cagagttaaa cgacaggctt acgaactctt
    97861 gattaaacgg cgttcaaaag cttgcatacg cggtaataag aacagccagg tcaaaaacat
    97921 gagaagccgt ttttcctggg ctgttcttat tacttgatgc agggcagctt tttcacaacc
    97981 tctttattca gataaaacca agcttggatc agcattcaac tgatagctag caaaatttct
    98041 tttttgcatt tccacatgtg ctgctgctcc aatcattgca gcattatctc cacaaagtcg
    98101 aagaggggga atcactagtt ctacctcagg gagtttagct gccaaagcat cctgcaatcc
    98161 ttcacgcaac ccttgattgg ccgctacacc tccagctata atcagttgct tgactggata
    98221 attttgacaa gctcgaagtg ttttagtaat caatacatcg atcacacttg cttgaaagct
    98281 agctgctaaa tcatttttgt ctagatcttc tccacgctgt tgtgcattat gcaccaaatt
    98341 gataaatgca ctttttaatc cgctaaaact gaaatcataa ttatcttcat ggatcatcgc
    98401 tcgcggaaaa tggtaattat cttttccctg atgagctagc tgatcgattt cttttccgct
    98461 tgggtaagaa agacctaata ctcttccaac tttgtcataa gcttctcctg ctgcgtcatc
    98521 tcttgtctcc ccaatgattt catatgatcc atcttcttgc atatagacta attctgtatg
    98581 tcctccgcta acaagaagtg ccatcaatgg aaactggaat ggtttaacca gacgggctgc
    98641 atagatatgc cctgccatat ggtttacagg aataagcggc aattggtgtg cccaagcaaa
    98701 agccttagct gcagaaatac caatcagcaa cgagccgaca agtcctggtc cataagtgac
    98761 agcgactgcc gataaatctt ctgccgacac accagcttct accagtgcat cttccaagca
    98821 taaggtgatt tgttctacgt gatggcggct agctacttca ggtactacgc caccaaaacg
    98881 tttatgactg tttatttgag aagcaacgat gttagataag atctctgttc catttctaac
    98941 gaccgctaca ctcgtttcat cacaacttga ttcaatcgcc agaatcaatt cttcattcat
    99001 ttcatcgtct ccgtttttaa ctttctgctc ataatgatcg catcttccgt cggattgcga
    99061 taatatgatt tccgtttacc taatatacga aacttttctg attcataaag ttttcttgct
    99121 gcttcattag atagacgtac ttctaaaaaa acatgcagcg aatcttttat ttgttccgta
    99181 atcagtaatt gtaacaaatg ccgtgcatgc ccttttcctt gttctgaaac tgcaacagca
    99241 atatttgtga tctcgacttc atctattact ttcgagtatc caataaagcc acagatctgg
    99301 ttatcttcag ctaaaagcag ataatcagag tgaggctgtt ggatgtctgc caaaaactgc
    99361 attttcgtcc aaggtgaacc atgtggataa gcattttcgc taatcatcca tacgcattct
    99421 gccaagtacg cttcatcaaa atcttttttt ctgcaaatca actaatctca ctcattttct
    99481 aaaagtttta tcatatccaa cgcatcttct tttgtttcag tgtaatatct ttttttgatc
    99541 gttgttgctt gaaaccccaa tttccgataa agtctttgtg catcttgatt actcatacgc
    99601 acttctaatg acatcgtctc acagcgattc attatagcaa agttctcgat ttcgtcaata
    99661 agcagcgaac cgattcgttt acgctgatat gccggtcgaa cggcaatatt cgtgatatgg
    99721 caatctaaac cgaacgctct tgaaccgata aaaccaatca ttcttccatt atcaaagata
    99781 cctagatata gatgaggaag cggtgacttc aattctgata taaaggcact ttttgtccat
    99841 ggcaattcgc cattatagac ttctcgttcg acatccagca gctctttgat atcttctgta
    99901 gtcaattctc ttagtacgta acgacgatcg atttgttcga ctgttttttc tgtataaatc
    99961 attttatctt gaaaaaagct tctggcatac gctctaaatt ttttcaacat aactttcgtc
   100021 tccaggtgtg tgcgtctcca accatttttc ttctgcttct actcgtttta aatagcgagg
   100081 aagaaaagct tgtttctctg caactggttc aactaaagca cctaattgag ccacagttac
   100141 accacttgga atatcccatg ctggaactgt attaatcatc gcactaggca atatttcctt
   100201 tatttcagag aagaatttgt gacaatcact cccgacgaaa taaatagctt cattcagctt
   100261 ttgtagttgt gtgaacaaat cagaagcaga aatatgtaca tcttcaagta cagtttctaa
   100321 tctattttct ttccagcggt atgccccagc gtatacattt tttcttcgag catcaaacat
   100381 gggcacaata atattatcca caccgatgca attagccgcg atggttttca gactagatac
   100441 tcctactagc tctttatcta atgtataagc aatcgttttt gctgtcgtta cacctatacg
   100501 aagccctgta taagaaccgg gaccatcaga aaccgcgatt cggtcaatgt cttttggact
   100561 tatttgaaga tctgcaaaca attggtcgat tgcaggcatc agtgttacac tgtggttgcg
   100621 tttgatattt gtttgtattt gtccaagaat ttgttcgtct tctaccacac cgatcgccaa
   100681 agtttggttt gcagtatcta ttcctaatgt aatcatatat ttgatccttt ctgctatgac
   100741 attctcgcct tccattgtag catacttttt tattctgagg atgaaaatac caaaggcaaa
   100801 actagtacaa taatacatga ttatctgctg gcgggcaaat tttgcccctt cctgaaacac
   100861 aaaaaagctg cggtatcact ccattttccc acagcttttc catcttttat ttcgttgatt
   100921 ctcgaataat caactctgtt tccacaataa tctttcttga aaccggtgct ttggaattac
   100981 ttaattgaag aatcgtctcc actgctagct ctcccatcca ttcggtataa acttttacag
   101041 tagaaagcga gggcgttaca tatttcgcta cactgacatc attgaagccc atcacagaaa
   101101 tatcttctgg taccactaaa cctttttctt gaatcgcttt cagtgcgcca atcgctaatg
   101161 catcattagc tgcaaaaagc gcatcaggaa catgcggatt cgtttttaaa tattgcttca
   101221 ctgcttgata tcctgactcg acagaaaaat ctgcttcgat aattggacct tcgtcgtagc
   101281 ctttttctgc caaaacttgt tgaaatgcca taattctggg atcttttagc cgctgatggt
   101341 ttttcttcgt atattctgtt ccagcaagca tagcgatatg ttgcgcttta tgggagacaa
   101401 agtgttcaat gactttttga acacttgact taaagtcgac aactagagag tcgattcctt
   101461 gagaagtgcc gtcagaatct accaaaagca aggcattttg ggatcctttc atttctaata
   101521 actgagcttc gtcgaatttt cctagtgcga tcgttccatc tgccggaaga tcactaatgg
   101581 aatcccacgt ttctttcaat aaagtaacgt ttgcttcttc tgcctttttt tcgattccta
   101641 ggcgaataga taaataataa agatcttcaa gctcttccgt atcgtcgtac cactggatca
   101701 ggcgaagcgt ttgcttagta tttgctgcat ttttacgatg tttcgtataa tttaagcgtt
   101761 ctgctgcttc aaaaattttt tgctttgtgg ctaagccaac ggaaagatca ggatcatagt
   101821 tgagaactct tgaaacagta gcaggagaaa ctcctgccaa ctgcgcaatg tctttaattg
   101881 ttgccatttg tctctcctcc ttttttacgt ttataaaatc gcagtaaatc gttcaaacgc
   101941 tgcctgtcct ttttcatctc gcttgaatac tccagcgtct tccagtacac gtgcaaaaac
   102001 ctgacctaca gatttttgta cgacatcggt gaccgtatct ttcgtcaaat caggatgttc
   102061 tttttttaat tgttctgccc acggacgatg atattcagcc atctggtttt cttctcctaa
   102121 taagaaatgc tctacttcta ctagttctgg tttcaaacga ggtggtaaaa cagcaagccc
   102181 cattacttcg atcaacccaa tgttctcctt tttgatatgt tggacatctt tatgtggatg
   102241 aaaaatccca tcaggatgtt cttctgaaac attgttgtct cgaaggacaa ggtccaactc
   102301 aaagtaattg tcccttcttc gtgcaattgg cgtaatcgta tggtgtggtg taccatctgc
   102361 tgaaaaagct ctgatagata ctgtttcatc cgaatatgct ttccattttt ccaatactga
   102421 gttagctgct tcaataagca agtttttctc tgttgattgc aaacggatca cagacatcgg
   102481 ccatttcacg actcctgcga tgacttgcgg ataatcttct agtttgataa gtttttctat
   102541 cggtgctttt gccataggaa attcatgacg tcctgcctga taatgatcat gagaaagaat
   102601 cgatcctcca acaattggta agtcagcatt cgaaccaaca aagtaatgag gcaagacttc
   102661 agtaatccga agcagtctag caaatgtttc ctttgtgatt ttcatcgggc ggtgttgttc
   102721 tgataaaatg atcgaatgtt cattgtaata agcataaggg gaatattgga atccccagct
   102781 ttcaccgtct agattcattc gaataatccg gtgattggtg cgggctggat agttcaagcg
   102841 acctctatat ccttcgtttt ccatgcaaag catgcaggta ggatagtcta cttttaccgc
   102901 ctcgcgttct gctgcgattt gttttggatc tttttctggc ttagataaat tgattgtgat
   102961 ttccagttca ccatactccg actctgccgg aaatttgatg ttttttgcga tggctcttgt
   103021 tttgatgtag tcatttttct tacttaaatt aaagaaatac tcagttgctt cctctgggct
   103081 tttcgaatag tgctgtgcaa agaatgcatt gacgactgaa ggtggcggtg tgagaaaatc
   103141 cattaattgc gcttcaaaaa tctcttgttc tgctggcaat tctgaaagaa caccattttc
   103201 tcttgcctta gcgacaagct gatccaataa gtctacagat tcttccttaa ctggtcttac
   103261 ttcaatgctt tctagagcat cttctcctac catccctaaa agacgattct gtaaatataa
   103321 gcggtccatt tccatccatc cgccagcttc gatcgcaagt gtggcaaaat cacaaatcgt
   103381 ttgactgatt gacatatctc attcccctat tcttcataac catttggatg gctgacatgc
   103441 caatcccatg ctgttttgat aatcgctttg atatctgtgt attcaggttt ccagcccaga
   103501 atctctctcg ctttttcact tgaagcgact aatcggctag gatctccagc tcttcttggt
   103561 gctatttctg ctggaatttc ttttcctgtc acttctctag ctgcttctag catttccttg
   103621 actgagtatc ctttgctgct gcctaaattg aagaagttgc tttcatttcc ttctttcaag
   103681 tattccaaag ctaaaatatg tgcagcaatc aaatcttcta cttgaacata atctctgata
   103741 catgttccat ctggtgtatc ataatcgtct ccataaacag ccaaggcttt tctttgacca
   103801 agagctactt gtaaaatgat tgggacaaga tgcgtttctg gtgtatgatc ttctccgata
   103861 gatgcatctg cttttgctcc ggctacattg aagtagcgca aagcgacata gcgcatgcca
   103921 tatgcttggt cacaccactt catcattttt tccatcatca atttactttc accatacgga
   103981 tttttaggat tagctggtgt atcttctgtg attggagact ctttcggctc tccataagtt
   104041 gctgcagtag aagagaatac gattttattc acgttgaact cgtgcatgac ttcaagtaag
   104101 atttgcatac cgtatacgtt gttgttgaaa tacatcaatg gtttttcgac agattctcct
   104161 actaaagagc ttgcagcaaa atggattact ccttcaatcg gttccttttc aaatacggaa
   104221 cgtagaaatt ctttatcccg gatgtctcct tcataaaaat gagcatctgg atgtactgct
   104281 tgtttgtgac ctgtgagcaa attatctacc acagctactt gatacccctt ttgaactagc
   104341 tggtctacag cgtgcgaacc gatataaccg gctccgccta gtactaaaat tgtcataaaa
   104401 aacactcctt tgattagtaa aattgtgttt gttgattcta tataatttaa aaaacgaagt
   104461 ttacttttat ggtgaaaaca aacaaagtaa aatttcgtaa attcatatgg taaatttata
   104521 ataaaacatt tagtaaacat tttcaagggt tttttgcaaa ggtttacaaa caaacgtaaa
   104581 actagccttt ttttctcttt tgttccataa tagatataac aaataataaa tgaggtggat
   104641 tcaatgaaaa aatttgtatc tggaatatta gtaggaagtc tggcaacagc cgctgccgtt
   104701 gctggtttgg ttgcttctgt gaaaaaaaca gtgatcgatc caattgacga aaaagaagca
   104761 atgatcgaag aaaaccgtaa aaaagcaatg cgtaaacgcg tttctcgtta ataattattt
   104821 aaaaatacgc atgaagactt tctaaaaaac agataagtca tcatgcgtat ttttatttgt
   104881 cagtcaatat aagttgtgct attttatctg cctgtctcag attccatgga tctgtataag
   104941 gtctagctac tgctgcagtt agccaatcca caccttcaac aggtattcca tagcaataaa
   105001 agtcagactg gatttcccct gaagcatcaa tcacgcgatt cgtacctcgc tcaacatcta
   105061 tagcttctga atgataactt cctgtattat ctgaaaatga aaaagggcga acaagtttgt
   105121 tttccttcaa attttttatg acaggattac ttgaacgaga aaagcttgtt tgtggcaatc
   105181 gagcttcaat caaatagcga ctgctgattt ctttatcttg tagagaaata acatagcggt
   105241 tgtgcttttg ctgaatatca aatggcggtt cgatcaaatg aaaaataccc gcatctatca
   105301 gtgctgctaa ttctttcgtc cgaatgattg gcggaccgat cgttaaaaag ctatttagat
   105361 gagtaaacca tccccatagt atttctttgt attccttagc agaaaaaacg tgccattcaa
   105421 tagcctgccg gattggatca cgccagtctt ttaatgcatc aaatgttgaa gcaaatgctc
   105481 ctgtgcaatt gcctttttcc gcttctttta tctgcccttc aataaatatt cggctagctt
   105541 ctgaaaaggg ctcattctga taggcaagag gagtttctaa atacgaccaa tcccatctat
   105601 aagggattag tgctggatgc tttccgagac actcctctga agagagggag agaaaatcat
   105661 gctcaaaatt tttctttgga atcggcaagt gatattcttc gatgattttc ttgtaataaa
   105721 acaactcaac gtcttttttc agatagtcaa aaaatgtttc gccagtcaaa aatcccgact
   105781 gatgccattg ctccaggttt tcttttgtta gtaaccgtgg ccatgccatt gctccgcctt
   105841 gcttttgatt tcttcctcga gggtaataag ggagccccct tcttgatcca ctgtatacaa
   105901 tcggttcctt gcctgatgga tgatagacca gttttccctt ttcgttctcg aagcgccctc
   105961 ctcttgatac tgtaaacaat ccgacataat caaaaaaact taagcctaga cctcttaaaa
   106021 agacattttc tttaggcggt atcttcgaaa gatctacatc tgcaggatta gaaggaagct
   106081 gatacagtaa aacatttttc tttgcgtagt ctacccacac tctttcttct tctgtctcat
   106141 cattttccca gtgaccgctt gctaaaacaa gctgatcgat agaatagctt tgctgatctg
   106201 tctgtaaaag ataaccatct tttcttttgc ttactttttt tactaaagaa taaacaaact
   106261 gaatagaagc tggaaattct tcttgcaact ttgagaaaaa ccagcgttga tagagtccgt
   106321 ataaacatcg agtagattgc tgatcttttt ccagacgatt gatttcttct ataattagtt
   106381 gcttattttt ggttaccgtc tgttcgatat aatctgtagc aggtccttta ctccattgaa
   106441 acaagttggg tccctgtgtt accaatcctc cactggacaa tgtttcatct gtaaaaagcg
   106501 tcacttgttg agaaacagaa ttcattaata actccggtgg ctgattcaac cgccaaactc
   106561 gacctccagg accattggga tcgaaaagaa aaagttcaag agaatgtctg tcctgattat
   106621 tatggagaat cctttctgct acacttaatc ctctaggtcc ggcaccaatg atccctattt
   106681 tcatttgcat gcctccattt cgataaattt tttcaataaa acagcatggt tctgatgttc
   106741 attttttgca ccataaacaa aagtaatgac tggatgttct ttcataagtt gactgagttt
   106801 aaaaatagct tgcttctttt cttcttcgaa aatcaattct tgctggtatt tctttgcaaa
   106861 tgaagcaaat cgttctggta catggtcaaa agttttgcgt gcttcattac taggtgcaat
   106921 ttctttcaac cacagatcta actgcgcttt ttcttttgaa attcctcgtg gccagaacct
   106981 atccacgagt attctatagc catcctcttt ttcagcatca aggtaaacac gttttaattt
   107041 gatcatagtt gtttccttct ttctgccttt tcgcttagct tatatatgta gataatagca
   107101 caaaataaaa aaaatgaacg gcacaactat ccattgcgcc gttcatgtga tcttggtcaa
   107161 aatctaatga ttgattcggt ttttaaagct gtcatacaat catctgtttt atactttttt
   107221 acttttgatt tttccagacc atccgtcata tccaccctta agtaaataaa tctcttgata
   107281 acctgcttta cgtaatttat ttgctgtacg gatgctcaag cttttctttt gatcgtaaat
   107341 atagacaggc tggtcttttc gaatagatcc taatgaatct ttcaaaacag tgtaagggat
   107401 gtttcttgca cctaaaatat gcccagcatc aaacacatct ttttcgcgaa catcgattac
   107461 ttgtgctttt ctcattcctt ctcgaaattc ttcttctgtc aaagtcgttg ctgaacgctt
   107521 ggccattact cgtagataga cttcccaaaa gatgattgca agcacaatca atagcaaaat
   107581 gatattaatt acccataaaa ccatgtaatg cctccgtttt tttaagcaaa tttcaaggct
   107641 aatgaggcag caccaatgac accagcttca ttaccaagct ctgctaattt gatttttgtt
   107701 gattctctta cttgcgggaa agtaaattct ttaaaatatt tctctacacg gctacgtaaa
   107761 aattctcctg ctgccgatac tcctccacct aacacgatac ttgacggatt taatgtattc
   107821 cccaagttgg cgcaagctaa acctaagtag aagcatacgc gatcaacaac catcaatgca
   107881 aacggatcgt cttcttgagc catttcaaag atatctttac ttgttacttc ttcaccgttg
   107941 tctaacattg ctttcagttt tgaatcccct gcgtattctt ctgccaagaa acgacctagg
   108001 cgtaccacac ctgtagcgct agatacagtt tctaaacatc cgcgtttacc gcaagtacat
   108061 tcgaaccctt caggatccac agtgatatgt ccgatttctc ctccagctcc gctcacgccg
   108121 tgaatcaaat ttccgccagc aacgatacct ccgccaacac ctgttcctag agtaacgaat
   108181 acaacgtctg gatcgttttc tccagcacct ttccatcgtt cacctaaagc agcaacattc
   108241 gcgtcattat cgatagcgaa tttgattcct gttcctgcct cgatcagttt tttcacaaat
   108301 tgaacttctg tccagtttaa gttatacgca ccaataaccg ttccagcttc gctgtccacg
   108361 cttcctgggg tacccatgcc gattccgata aagtcttcgg ctttcatatt atataaattc
   108421 aaacgatggt tgattgattc aatgatttca ggaacgatat gcttaccatc atccaaaata
   108481 ttggtatcga tgctccattt ttgttgaatc tctccttctg gtgttaaaat tgcaaatttt
   108541 gctgttgttc cacctaaatc aatcccaata atcttcttgt ccattacaaa tttcctttct
   108601 ttcggctttc ttcaattcgg tgctctcttt ttaatatgcg ccacgctgtc atgtatgtat
   108661 catgatcaat caaacggcta tcatacagat tacgcaattc gatagtcatt aattcaatgt
   108721 catagatgcg tgcacccaca tagataaaga tgccaaattt tttgaacagc tgctgtacat
   108781 catataagct ctccatcttt aagcacttcc ttcatattat acaagtaaac catatttttt
   108841 taaacccagt aaaatacata ttacaaaaag aaatacaaaa actagtgtag aaagaatcct
   108901 ttggtgtatc gaatagcttg tctgttgttt cggtagaccc aaaacattcc ctaacactaa
   108961 tccgccaatt agcccaccga catgtcccca aacatctaca gaggtatcca gaagaccaaa
   109021 aacaaatgtc aacacaataa ataaaagaaa atgtctgact agctgctgga tcgctgggtt
   109081 atgtttaaaa tgaaacccta agataaacaa cgcaccgaac aaaccgaata tcgaagtact
   109141 tgcaccacca gacagaacat tcgcttcgtt aaaagcaaag cttgctgtat ttcccattat
   109201 cccgctgaac atataaatca agaaaaaacg ccaatggcca tagattgcct cgatttgctg
   109261 ccccataaaa tacagtatca gtgagttcat tacgaaatgc atcagtccaa aatggatgaa
   109321 gattggtgtc actaaacgcc accattcatt gaagtgaaca agataaggac catacattcc
   109381 ggcataataa gggatctcaa gtcgcggaaa taattccatc atgaggaaga ccgctgtctg
   109441 tatccctaaa aaagcatagg tccataacgg tcgtcttaac catgcacgca attttatttg
   109501 ctgttgataa ttcatgaaaa cctcccattt cattttagtc aataaacaat tgttggatct
   109561 tctgatcaaa gctctccggt tgccattgtt cattcaattg ttcacgaaaa acaaggctac
   109621 atgttttttt atgaaaatta tttaaatacc ggtcgtaata accaccgcca aaaccgattc
   109681 gataaccggc tctattgtag ataatacctg gtacaatgag gagatcgatc atctccggca
   109741 aatagagctt ctctgattgt ggctcaagaa caccaaaact cgaacgtaca agaacggact
   109801 gttcatccat ttcataaaac gccatctgac gtttcggcaa agttttaggt acaactattt
   109861 tcttttgttc tttttctgct cgttggataa ccggctgtgt atccagttca aattcattcg
   109921 ataaagtcgt ccctatcact tttgctgact tccagtactc gctggcgaat agctgtttat
   109981 agattcgctg ttctttttcc tttttcttgc cacttttggc cagatttttc agcttttcga
   110041 ttcctttccg gcgtaatctt actttcaatt ggtccaaaaa ctcacccttc cttctctcat
   110101 aaaatggtat aggaaaaaaa gaaaaatagc aatcgaactt tcaaataaat gcataaatag
   110161 aataaaaaga agacctagaa atgattggcc ttcctttttt aataaatttc aactgttcag
   110221 cgcgtgtttt tgtctgataa aaagtgcata cagaaaatat ggcgcaccaa aaagggcaat
   110281 caaaattcct gtaggtactt ccccacttgg tagaatcact ctagcaacca tatctgcact
   110341 aagcagaaaa atggaaccga acaaaccgct cagaacaaag gtccagttat tttctttacg
   110401 tacgactagc ttcgcagcat gaggagctag tagtcctaca aaagataaac tacctgtcac
   110461 cgctacacta ccgcttgcca aagcaacagc taacaacaaa aggatttttt gacttttagc
   110521 cacgttaagg cctaatcctt gcgcgcgttc ttgaccaaat gatagcaatc caatcctctg
   110581 tgcataaagt cctcctagcg gaattaagat aaccgcccat ggaagcaatg cccaaacata
   110641 aggccagctc gcaccccaga ttgatcccgc taaccatgca ttcacaaatc cataattttc
   110701 cttagataat tggatcgtgc atagcaatgt taatgcagaa aggccggcat taacggcaat
   110761 accggacaat aagattcgat tcatacccaa aaagccattt cgatcatagg ccgcaagata
   110821 gacacagcaa gcagctaaaa caccacctag aaaggctaca actagcaata gaaacggcag
   110881 cgaatagtgc gaaaagaaac ctaaataaag catcactaaa aatcctgctc cggcattaat
   110941 gcccaatata ctagaatctg ccaattcatt tcttgttact ccttgcaaga tataaccaga
   111001 aacgccaaga caagctcctg ctaataaact gatcagtaat cgaggaactc gaaattctct
   111061 aacaatcagc gccaaagaag atgattcttt ccctatgaac gtggcaaaaa gctgatccag
   111121 gtaaataaaa ggcgtaccaa tcattaaact acctatagac aggatgacaa gtacaaaaag
   111181 caagaaatag aacgtccaat atattttttt caccgttgtt ccctccttac ttgtatcagt
   111241 aaaaacggaa cgccaatcaa tgcaatgact aatccaaaag gtgtttcaaa agggggattg
   111301 atcatcctcg ctgtaaaatc cgccaacata accaatccac cgccaactaa aaaagagaca
   111361 ggtagaacat aacgatagtc cgttccaacc attccgcgaa caactggcgg aaccaacagc
   111421 ccaataaatg aaacaggtcc gactaacgaa acggcaatgg ctgctaacac tgcaactaga
   111481 cagaaaacaa tcaaccgcgt tcgtttagga tgacttccaa gagctaatgc atgtgtttca
   111541 ctcaaatgaa tcaaagatat tgcttttcct aatgaaaaag aaaccaaaac agcaagtata
   111601 tataaaggaa acaatactgc taattgtttc catgtgatat tggcagctcc gcctacaaac
   111661 caaaaagcaa gatcctgctg cagattaaag aattgggtaa gtgcttggct gatagcagta
   111721 aaaaaagaac taatagctac gccagctaaa atcagctgta aaggattcat gcccattttc
   111781 gaaaactgca aaaaaccaaa tacgagcaaa gttacagcaa aagaacctgc caatgacatt
   111841 agaaacacag aaaaatcaga agctttaggc caaaaagcaa aactaagggc cattgccaac
   111901 gaagcacccg cgttgattcc tagtaagcct gaatctgcta aaggatttct tgtcactcct
   111961 tgcatcaatg caccgctcaa tgcaaaacaa ctccctacaa gaaatgctcc cgccacacga
   112021 ggcaaacgaa tatttcgtat gatttggtga ctttgttttg atctatcaaa atcaaacaac
   112081 gcctgccaaa aatctgcttt tcccacagtc gctgcgccat ttgaaagagc aacaaaaaaa
   112141 ataatcaaaa gaacaaaaca gaccaaaagc aggagtctat ttttcttcat agtcctcata
   112201 attgatcctc ctgctctttt ggcaacaaat cataggttag aaaaactggt ttatttgttc
   112261 ttggaagcgt gacaatcgtt gcatcaatct caaatatttt tttcatacac tcttttgtga
   112321 tcacttcttc aggtgtacct tctgtgatca acttaccgtt tttcattgct aataaataat
   112381 ctgaaaaacg tgaagcatga ttaatgtcat gaatcgacat caagatcgtt gtttgtttca
   112441 tttgattgat ttcagtcaat aactgtagga tctctaattg gtgtgccgga tctaaaaatg
   112501 ttgtcggttc atccaagatc aagatatctg tttcctgagc aagcgccata gcgatccaga
   112561 cacgctgggt ttgtccacca gacagcgttg cgatatcccg catacgaaat ccagctagac
   112621 ctgtagcatc caacgcccac tcgattgctt catgatcttg cgtgtccatg ccactgaaca
   112681 gtttttgata agggtatcgt ccgtaagata ctacttcttc tactgtcata cctgtagggt
   112741 gttcactagt ttgtgctaat aatgtaattt tttttgcaag ttcttttgaa ctgtatgtag
   112801 agatatcaga gttattgaca atgatctttc ctgatttcac aggtagtata cgggtaaaac
   112861 ttttcaataa agtagatttt ccacttccat ttggcccaat caaactagtg attttccctt
   112921 caggaatcgt aacagacatg ttttcaatga tttttttgtt ttcgtagccg gctgcaatgt
   112981 cagctgctct taatctcgtc atttcaccca tcctttcgct gaaaatcatt ctcaattatg
   113041 acgctgtttc aacatttcgt caagcgctac tttcatatct atagccaaat gaagcggttg
   113101 acagcgttcg aaatatcagg aataataacc aatgagaaag attctcaatt atgttaggag
   113161 gaaagaaatg aaattaaaaa caaaagtatt cacattatct agcatattgc tgctggctgg
   113221 agtactgagc gcttgctccc cctcttcaga taaagaaaca gctacaactg ccaattcgac
   113281 gacttcatcc aatagtactc atacagtcac agatacactt ggacataaag tagagattcc
   113341 aaacgcgccc aaacggatca tcggcagtta cttagaagac tatctgattg cactagggga
   113401 aaaacctatc gcccagtgga ctgttggcag tggttccatt caagattatc tgcaagatga
   113461 tttaaaggat gtcccaacga tttcttatga ccttccttat gagaaagtgt taagctttga
   113521 gcctgatttg ctgttgattt cttcttccgc tactgtcgaa ggcgggaaat acgaacaata
   113581 tagcaaaatc gcgccaactt atgttgtaaa aaacggaaca gatgtcacat gggaagaaca
   113641 actaaaagat gtcggcaaag ctttggcaaa agaaaaagag gcagaaaaaa tcatttccga
   113701 ttatcaaaaa tccatcaaga aaactcgaga agaactagca gataaaatcg agaacaagac
   113761 agctgcagtg ttgtgggtga ccaacaactc agcctttatg gtcagcaaaa atcggtcaag
   113821 tggaagaatc gtatacgacg atctggaatt tggtgttcct gatctagtgg aagaggtctc
   113881 caaaaaagcc acttctgact ggtctgctgt ttcctctgaa aagctagctg aattagatgc
   113941 tgactacatc atccttgtga acagtgacaa agatgctgcc atgttcaatg aaccaagctg
   114001 gaagaatctt aaagcagtga cagacaatca tgtactgcaa ttcggacctg aatctagttg
   114061 gctatataac ggacctattg ccagtcagga aatggtcaat gatatcaaag aaaaactaaa
   114121 ttgattttaa ctaaaaaaag aatcttcacg attagtcgtg agatgctttt tttcttatta
   114181 acaaactaga cgcatagatt ttattcttct tttgaagcaa ccctattttt tactctttcc
   114241 catttttgaa aacgatgggc atatagattt tcttgatccg ttatcccctc atactcctct
   114301 ataagggcga agtctgaaaa atcaatattc ccaatatacg tatcgccttc aaacgtgcta
   114361 tcgatcaatg ttcgccagat ccgaccagtg taaggaagaa gttcttgaaa aatccgacta
   114421 ccacccgaaa catagatatc ttctgagatc gtttgactat acgacaaaag ttcatcgatc
   114481 gaatgcatta cttccgcatt ttctttcgtg cgaaaatttg gttgcgttgt caacacgatg
   114541 atatggcgat aaggaagtga aagatccccc attccttcat aggtctttct tcccatcact
   114601 aaaattcgat ccattgtatg ttcgcgaaag aaacgcatat catttggcaa tcgccatggt
   114661 aacaaaccat ttttgccgat cagaccattt ttatcttgtg cccacatgga aataaacata
   114721 ttatccgctc cttatgattt tagatgtttt gagataaaaa aagtctcaat tctttgacca
   114781 gcaaggaatt gagaacttta aaaacattat tttgtttcac ggtgcaaagt aactttgcgt
   114841 tcgcgtgggc aatatttttg tttttccaaa cgatcaggat tgttacgttt gtttttgctt
   114901 gttagatagt tacgttcttt acaagaagta cactctaaag tgatgtttac gcgcatgttt
   114961 ttccctccca tttttacaag aatcctctaa gatgactctc agacttgatt atcttaccat
   115021 gattttttct agattgctag tgtttttcac gattttgtta agtaaaacta cttgacgata
   115081 aatacaacgg ttttacttct caaacaaaat ctttttcttt ttgtataaat acccttacac
   115141 ttgtttatat agattatgtt ttttaataaa gggggatact aatatgccat ggaacatgaa
   115201 ggactttcct gcatcaatga aaaacttaga taaattgaca agaaaaaaag caatcgacat
   115261 cgcaaatgca ttattagatg aagggtaccc tgataaccgt gcgatcccaa ttgccattga
   115321 tcaagcaaaa aaatggtatg aagatgctag tgaatcagaa aaacgaactt tcgaaaaaga
   115381 aaaaaatcca agcaagacgg atgaacacga tacgaatcct cgtgctggaa aactgcttga
   115441 ttcagatgtg atcgtagaat atgaggaaga acaatggatc gtgaaatcta aaggggcaaa
   115501 aaaggcaagc aaccattttg atacaaaaaa agaagcaatc gaaaaaggaa agcaagtagc
   115561 acaaaacaaa gaatcaactt tgttcattta taaaaaagat gggacaaaag aaaaagaaat
   115621 cgattattga acatatgtaa aggggttgtg acgaaaatcg tgtcacaacc cccttatgtt
   115681 cgaaacaatg gtgttcctct gccaactccg aaccataagt cataatatct ataaaacggg
   115741 aagagctgtt ttttgaaatt gtttcttatc actcagtgtt aaacggtagg agaaaacctc
   115801 ttttttattg atatttgatt ttcatcaaac agtcacatag tcgattgctt ctgcttgcgg
   115861 aatcgtttca tctacaaagt agactttata ccatgtcaag aaactgaaga ttgtccagat
   115921 ttttctttgc tcttctttac gtccttcgtg atggtcatct agcaacttca tgattttttc
   115981 ttgatcaaaa aattcttttg caaaatctgc ttcgaataat gctttgactt gttcgtagcc
   116041 gtgttcttct ttcaaccaag ctttgattgg cacagggaat cctaatttca cacgattcga
   116101 ccattcttcc ggaagatgtt tgttcgcagc ttgtctgaaa atatcttttg tgttgttttg
   116161 attcaataaa aacttacttg gtatttgttg agccaatttc atgacttcga tatccaataa
   116221 aggtactcgg acttccaaag aacttgccat agaaagttta tctgccttta acaagatatc
   116281 ttttggcatc cattgatgaa gatcgacata ttgcatctta ttgacttcat ctttgattcc
   116341 ttctgttttc tcgtaatgaa cagtcatgat ttcatccaca gatggtgctg tttgatattt
   116401 tggtgttaac acttctgatg cttctgattc ttcgaacact cgagcatgac cgataaaata
   116461 ttcttttgca ggagcaagtg attcatataa atggatccgt ccatggaaat ttttcatttt
   116521 tccgatttta cgtcctaaat tatagcgtgt tccttttggt aattttttca atccttgagc
   116581 aatcacacgg atgaattttg aattcgtatg gaatccatac gtttggtatc ccgcaaacag
   116641 ttcatccgcc ccttctccag attggactac ccgcacactt tgtgaagcaa gatttgctaa
   116701 aaagtacaaa ggtacgcaag aaggatttga atcaggttca tctaagtgat actggatcaa
   116761 agggaatgct ttgaacgaca tgtctccgtc gatcactgct gctgtattat ctaagtccaa
   116821 tagttcggtt agttttctgg cttcaatcgc ttcattatag gttttatcat caaacccgat
   116881 tgagaaagaa tgatctggtt tcaatacaga ggttacataa ctggaatcaa ccccgctgga
   116941 taagaaagaa ccaacttcta catcactgac cgtatgtgct tcaatagaag cttgaacggt
   117001 ttcgtcgatt ttttcgatcc attcttgtcg ggaatgcgtt tcttttgttt caaaatctgc
   117061 atcccaatat tgctgaatgt ctagttttcc atctttatac gtataataat ggccttcagg
   117121 caaacgatag acatctttga agaatgtttc gccgtttaat ggagaatatt ggaaagtcat
   117181 ataaggtttc aacgcttctt tgttcaattc tttgttaaaa tcaggatgag gcagaaaact
   117241 tttgatttct gaaccaaaca taaatgttcc gttcatttct gcataataat atggtttgat
   117301 cccaaagtgg tctcttgcac cgaataactc attcttttca ttatcccaaa tagcaaaagc
   117361 aaacattccg cggatctttt gcaataattc tgttccccat tcttcgtaac catgcaaaag
   117421 gacttctgta tctgcatgtg tttgaaaaac gtggccagct gcaatcaatt cttctctcaa
   117481 aggctggtaa ttatagattt cgccattaaa aataatgatc tttgtccgat cttcattgta
   117541 aataggctga gtaccgccct ctaagtcaat aatacttaat cttctgaatc ctaaagcaac
   117601 atgtttatcg atatattctc ctgaactatt aggtccacgg tgaacgattc gatccatcat
   117661 tgtattaata attgtttttt tgttgtcctt gtcgttaaca aaacctacaa taccgcacat
   117721 ttaactttca catcctaata taaaattact gtttatttca ttcatatgca tcttatcata
   117781 gaataaatag cggacgaata ttttctctct tacaatttcg tcacgtgaaa acaaaagatg
   117841 aaagtttctg tttttacaga aaataaagtc ccaatatcta atttaccatg ttttcttttt
   117901 tgaggctacc ttattctctt cgtgttaaaa aaatattagt ggatgctatt tccaaaaaaa
   117961 acagcaaaaa aagacacgac ctaaagatcg tgtctaatta tgactgtatc agaaaatatg
   118021 ataccaaacg gatctattca ttaattaatt gacatagttt atctgttgct cttttatgac
   118081 tggataactg accaattcat gacgatccaa gtcttcttta tttatattta cagcagtaat
   118141 ttgactgtct tcatacgtac gataataata aatcccttta tcaacgttac agcaagaaga
   118201 ataaatcgta tattcgtatt ttccttctcc agtatcgcat actccttttt gttgctcgac
   118261 tgagcctagt atatgaaaaa attgactgat actttcagat tctgaatcac ctgatgcagc
   118321 attcatttta gtaaatgtgg cttttacaaa tcgagaaaca gaagagagat ctccaggtaa
   118381 gcccaatcct cccatcccac gactataaac attcaagctg atctggtttg aaaaatgatt
   118441 ttctggtgtt ccatttgata gcgagcgata attgttcaga ttaaataatt gataatcaaa
   118501 tggcggatta tttgtcaaca caccgacagg attatcatat aaatgaagtc catctttcat
   118561 actttcaatt actatcgatt tttctttatc agctaataac cagtgtaaag gtgacaaggg
   118621 tagtttttca ctaaaatcga tattgactag attgatagta gccaataatt ctttagcttc
   118681 gtctatggtt gagcattgcc ctagtatcca tggaataaac tcaaatggtg caacgttatc
   118741 ttttccttct tgtaattctt tataatcagc attgccagga aaattcagtc ctgccatact
   118801 caaccctttt tcatttgtag cctcataata gagtggatag ttggataccc cagctgctat
   118861 tcctatcatt gcataatgtt tatctaaatt ttttaccttt ctaaaatcga aacgataatt
   118921 tcttggagta atagtgacta cttcattata agacatctca taatcaaaat tccttccaaa
   118981 ataatggtct ttcgttgcat aagtgattgc ggtacacatc gttttccctc ctaaaacaaa
   119041 tcgtttttac acttttatct tacatctagt attttttttt atcaaaaaaa aggccaaaga
   119101 agattgattt actagcattt ataaaaaata gtactcaggg ggaatcaaaa aatattgtag
   119161 gttaaaagta caacaataag gggctgtgac aaaagtcttg tcacagcccc ttattccgaa
   119221 caaacggtgt tcaaaagctt gcatctgcgg taataagccc aaccaaacga aaaaatagga
   119281 aaagctattt ttgtttggcc gttcttatta cttgatgcag gacagcttct tcacaacctc
   119341 taatcgttga tataaggaag gtacaggatt tgaacctgcg cgccggtatt agccggttcg
   119401 ccggatttcg agtccggtgc attaccactc tgccaacctt ccgtaagtac tatttttaaa
   119461 cttttttcac gaaatgtcaa gcctatttct aatagataaa taacagaaat cgcttttttt
   119521 agcaaaaaag tccattgaca gtttgcagcc aacggactta ccgatcaaat tcatactgat
   119581 agaacactat ctgattattt caggattatc taatgctaaa atcgagtcaa ttgtccgttt
   119641 gatcagtgca atgatttgtt cttctgttgg atgcatgatg tttgatgaca tcaatgacgc
   119701 taagccagtc actgctaccc atgtaccagt atgcagagca tcgacatatt catccgataa
   119761 ttgattgtat ctttcatctt ctttaactat ttcacggaaa taattgtatg aaaaatcatg
   119821 cattttcttt ccgtccccat gttcatcaat gtacaatgcc atgtaaagac tatgatgctt
   119881 ttttgcaaag tagatatagt tcaaaccgag atcaatgatt ttatcaccag tacgttcaat
   119941 agggaaaaca tcttctttta gttgttcaaa gatagaatcc agcaacgtat tttttaaatc
   120001 ttccatgttt ttgaattcca gataaatcgg ctgtgtcgaa atccccatct ttttagcaat
   120061 atttctcgca gtaaatcctt taaacccttc ctttgcaaca acatcataag cagcttttag
   120121 aatttgatcc ttggtataga cttttcttct cattaaaact cccccacttc tttactgcag
   120181 tatatgttgt tttattgtac cctattttta gcattttttg caaacatttt actcaaaacg
   120241 ttatatttta aatttttttc agtcttcttt aacttttttt tgcaaaatta aaaaaatttg
   120301 gttaaattca atgggttccc ttacattttt agttttgacc taaatgatag ttgtccaaat
   120361 ctttcatttc aagttatagt taaagaaaat gaaaaagaag gtgtgtaatg gaaaacgaaa
   120421 ctgacgttat ttatattcat cctcaaaaac gaatcgtttc acagaaaaga aagtattttt
   120481 atcttggttt tacaggtgtt ttttttcttt ttattggctt gctttctaat actcctactg
   120541 ataattggag tggattgcta actattctta cctcgccaag caatcttttg acagattatt
   120601 ttgctttagg tgttttcgga agcgcattca taaatgtagg gattttgacc ttactttctg
   120661 tgcttttagc ttatcggcac aaggtgattt taaacggtcc cttatttgct tcgattctaa
   120721 cagttaccgg tttctctttt tttggcaaaa acctttataa ttctatctca atcattttag
   120781 gtgtgtatct atacgctgta tttgtcaata aacctttttc tcagtacatc atgatcggac
   120841 tgtttggtag cgtattatca ccggtcgtta gttatatcac ttttggtatg cgttttcctt
   120901 tactgatagg tattttattg gggaatttag ctggcatagc aattggtata cttcttccgc
   120961 ccttagctgc tcaaacttta gttttccatc gtggattcac actttataat attggattca
   121021 cctctgggtt gattgcgatg acttttactg ctgttttgag gttattcagc tattcaatcg
   121081 tcgaaaatac attggttttc aatgaatatc actttcctct catttggatt atttttggct
   121141 ttttttcgct gacagtcgga attggtttct attataattc ctttcggctt tcggggattc
   121201 gagaaatttt cgattcatct ggaaaattga caactgattt cattgctaat tctggtattg
   121261 gtgctacttt gatcaacatg ggcttagttg gtctgatgct gtcttcttat gttttgctgg
   121321 ttggcggtca gttaaatgga cctgtcatcg gtgctatttt atctgcggtg ggtttcagtg
   121381 cttttggttg tcatttaaaa aacagttttc cgatactagt cggaatattt attgcttctt
   121441 tgtttggaac ttttcatgag atcaccagta ctggcatgct tgttgcagct gtgtttggga
   121501 caggtcttgc gcccataagc ggtttttacg gcagttttta cggtgtaata gctggtgtgc
   121561 tacatattgc tcttgtccat aacgtcagca ctttgcacgg aggactaaat ctatataaca
   121621 gtggtttttc aactggtttc gttgcaggta tccttgtacc gatactagat aactttaccg
   121681 ctgtcagaaa ggaaaaaaag acacttggaa aaagaattat caaaaagaat catcgatgag
   121741 cttcttactt atttatattc ccatgaaata actgaaatac gtattggagt agaatttgct
   121801 gaggaagggc ttttcataga gatacagggt acggcagaaa ctcagccaga agatttagat
   121861 gtacttgctg atttgctgaa caatcctcgg gaccctagta tggaaatcta ctatcaagaa
   121921 ctattaggta atccccgaca tgatcgggaa gattatcatc tgttaggtag tttgattgat
   121981 gacgtggaaa tcatgtatgc ccagccgatt atcaatatta agatctttcg acgtgcttct
   122041 cattcctatt attaacccta ttttctattt ataaaagact gaatcaaaaa agcagctcct
   122101 gaaagttcga ttaaaatcta ctttcaggag ctgttcaagc ttgacattat tgattttcca
   122161 atccttcata cacttcatct gttacaggtt ctaaaaactc tgaattacca gcagtgatcg
   122221 ccaaatgttc aaaccaactg tcttttgtcg caccatgcca atgtttaatc cctttgtgcg
   122281 ttacgacgac atctccagcc attaatcgtc ttgctggctt tccttcttcc tgataccagc
   122341 cttctcctcc ggtcacaagt aagatttgat agccgtctgt atggacatgc cagtgattgc
   122401 gacaacctgg ttcaaaagtt acattaccta caccaacaga aacttcggga tcattcacta
   122461 acatattcag atagctttgc ccggtaaata cttgagcgta agcttcgttt ttttcacctg
   122521 ctggaaaaat cacgccattg tgtatttctt cgtgttttgt catcatttac gcctctttct
   122581 tatcttcgct attttcttct aaatagattt cttttgctaa actaaaagct gaccaagctt
   122641 ttggccattc tacataaaaa gctaaatggg taatgatttc tgctatttct tcactagtaa
   122701 tgccattttg cttgccaatc ttcagatgag ctggcaattg ttcaaaattt cctcctgaaa
   122761 ttaatgcaga tatggtgatg atactacgct gatgagcaga taattcttct ctggaccata
   122821 cttgtccaaa taaaacatca tcatttaatt ctgcaaattt tggtgcaaaa tctcctaatt
   122881 gatctcgtcc tgcggtttgt ttttctgcca tttctcttat tctcccttca cgactgttag
   122941 gtgattcaac tatggttcta aggcaacttt attttctatt gtttcttcgc atttcatttt
   123001 aaatgtagtc tttcagcctg tccaatgctt agtttattca gtcgatatgc tttttaagca
   123061 tagttgctaa cgcttttttt attttaaaaa aaacaagtta ttaaataagt ctttagttgg
   123121 atgttttttt gagatcaatc ttttatactt atgatgaact tacaaaattg tttgttttct
   123181 gtcatatcaa aaaatggcgc agttagttgc ttttctagta aagtatagtt aacaaagaac
   123241 ctctaaggag ttgatgaata atgaatattg ctgcctctcg aaaactgata aatttcatat
   123301 ccattatcgg attaggccta tcaatcgcgc tgacgattta ttttattaat ttaggtgttt
   123361 tcaaagattt gaatgcgtta agaggattag taggtgattc catcatttta ggaccgatta
   123421 tttttgtctt catccaaatc ctgcaagtag ttattccaat cattcctgga gggatcagta
   123481 ctgcagctgg tgtcctgata tttggccctt atgctggatt tatctataac tatattggaa
   123541 tctgcattgg ttcgattatc atttttctgc tagggcgtcg ttatggaaag ccattcatac
   123601 tttccatgat tagcgataag acatataaca aatatattgg ctggctggat aatcaaaacc
   123661 gttttgagaa gctgtttgct ctagctattt ttcttccagt tgctcctgac gatgcgttat
   123721 gtttgatggc tggattgaca aacatgtcag tgaaacgata tacactaatc attttgattg
   123781 ctaaaccact gtcgattttc ttatatagta tggccttgat ttatggaggt caatatctaa
   123841 gtggtcttct tggataatat ttattttgta aaattagtca ttgattgaca atgtt
//
LOCUS       DBBGSZ010000003       123207 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.003, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000003 DBBGSZ010000000
VERSION     DBBGSZ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 123207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 123207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..123207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.003"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(552..2165)
                     /locus_tag="ACIZE5_000248"
     CDS             complement(552..2165)
                     /locus_tag="ACIZE5_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGC6107431.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2306..3214)
                     /locus_tag="ACIZE5_000249"
     CDS             complement(2306..3214)
                     /locus_tag="ACIZE5_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6107432.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            3397..4521
                     /locus_tag="ACIZE5_000250"
     CDS             3397..4521
                     /locus_tag="ACIZE5_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGC6107433.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            4748..5665
                     /locus_tag="ACIZE5_000251"
     CDS             4748..5665
                     /locus_tag="ACIZE5_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6107434.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            5658..6491
                     /locus_tag="ACIZE5_000252"
     CDS             5658..6491
                     /locus_tag="ACIZE5_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6107435.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            6574..7692
                     /locus_tag="ACIZE5_000253"
     CDS             6574..7692
                     /locus_tag="ACIZE5_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGC6107436.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            7713..9584
                     /locus_tag="ACIZE5_000254"
     CDS             7713..9584
                     /locus_tag="ACIZE5_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HGC6107437.1"
                     /translation="MKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQIDYIHQGVG
                     YGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYWGEIHERDQR
                     MVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQFFKIIVGTII
                     QKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYGLIYSVLEPE
                     KPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAMLWADLLPFKL
                     GEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLWLNKIFLLLA
                     LPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPNFHTLTNEKY
                     LKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKTYGQFIVRNN
                     VRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLYETGFAIECS
                     PEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLMTWENTFIPG
                     LEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKNNKKRLKLC"
     gene            9578..10801
                     /locus_tag="ACIZE5_000255"
     CDS             9578..10801
                     /locus_tag="ACIZE5_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGC6107438.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(10887..12821)
                     /locus_tag="ACIZE5_000256"
     CDS             complement(10887..12821)
                     /locus_tag="ACIZE5_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGC6107439.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            13047..13703
                     /locus_tag="ACIZE5_000257"
     CDS             13047..13703
                     /locus_tag="ACIZE5_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HGC6107440.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(13777..14130)
                     /locus_tag="ACIZE5_000258"
     CDS             complement(13777..14130)
                     /locus_tag="ACIZE5_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HGC6107441.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            14322..15251
                     /locus_tag="ACIZE5_000259"
     CDS             14322..15251
                     /locus_tag="ACIZE5_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HGC6107442.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            15262..16098
                     /locus_tag="ACIZE5_000260"
     CDS             15262..16098
                     /locus_tag="ACIZE5_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HGC6107443.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            16346..17122
                     /locus_tag="ACIZE5_000261"
     CDS             16346..17122
                     /locus_tag="ACIZE5_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HGC6107444.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            17298..18041
                     /locus_tag="ACIZE5_000262"
     CDS             17298..18041
                     /locus_tag="ACIZE5_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6107445.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            18034..19614
                     /locus_tag="ACIZE5_000263"
     CDS             18034..19614
                     /locus_tag="ACIZE5_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HGC6107446.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(19865..20344)
                     /locus_tag="ACIZE5_000264"
     CDS             complement(19865..20344)
                     /locus_tag="ACIZE5_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGC6107447.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(20360..21112)
                     /locus_tag="ACIZE5_000265"
     CDS             complement(20360..21112)
                     /locus_tag="ACIZE5_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGC6107448.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            21229..21299
                     /locus_tag="ACIZE5_000266"
     tRNA            21229..21299
                     /locus_tag="ACIZE5_000266"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21261..21263,aa:Gly,seq:ccc)
     gene            21660..22385
                     /locus_tag="ACIZE5_000267"
     CDS             21660..22385
                     /locus_tag="ACIZE5_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HGC6107449.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            22640..22906
                     /locus_tag="ACIZE5_000268"
     CDS             22640..22906
                     /locus_tag="ACIZE5_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HGC6107450.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPSYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            22903..23334
                     /gene="ruvX"
                     /locus_tag="ACIZE5_000269"
     CDS             22903..23334
                     /gene="ruvX"
                     /locus_tag="ACIZE5_000269"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HGC6107451.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            23359..23664
                     /locus_tag="ACIZE5_000270"
     CDS             23359..23664
                     /locus_tag="ACIZE5_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HGC6107452.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(23745..24890)
                     /locus_tag="ACIZE5_000271"
     CDS             complement(23745..24890)
                     /locus_tag="ACIZE5_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6107453.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(24951..25598)
                     /locus_tag="ACIZE5_000272"
     CDS             complement(24951..25598)
                     /locus_tag="ACIZE5_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6107454.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            25792..26085
                     /locus_tag="ACIZE5_000273"
     CDS             25792..26085
                     /locus_tag="ACIZE5_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107455.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            26129..26440
                     /locus_tag="ACIZE5_000274"
     CDS             26129..26440
                     /locus_tag="ACIZE5_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107456.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            26437..27061
                     /locus_tag="ACIZE5_000275"
                     /pseudo
     CDS             26437..27061
                     /locus_tag="ACIZE5_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            27202..27360
                     /locus_tag="ACIZE5_000276"
     CDS             27202..27360
                     /locus_tag="ACIZE5_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107457.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            27361..27723
                     /locus_tag="ACIZE5_000277"
     CDS             27361..27723
                     /locus_tag="ACIZE5_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107458.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            27760..28608
                     /locus_tag="ACIZE5_000278"
     CDS             27760..28608
                     /locus_tag="ACIZE5_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HGC6107459.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            28598..30073
                     /locus_tag="ACIZE5_000279"
     CDS             28598..30073
                     /locus_tag="ACIZE5_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="HGC6107460.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            30339..30746
                     /locus_tag="ACIZE5_000280"
     CDS             30339..30746
                     /locus_tag="ACIZE5_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HGC6107461.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            30749..30964
                     /locus_tag="ACIZE5_000281"
     CDS             30749..30964
                     /locus_tag="ACIZE5_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107462.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            30968..31348
                     /locus_tag="ACIZE5_000282"
     CDS             30968..31348
                     /locus_tag="ACIZE5_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HGC6107463.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            31482..31637
                     /locus_tag="ACIZE5_000283"
     CDS             31482..31637
                     /locus_tag="ACIZE5_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HGC6107464.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            31706..32179
                     /locus_tag="ACIZE5_000284"
     CDS             31706..32179
                     /locus_tag="ACIZE5_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HGC6107465.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            32176..33870
                     /locus_tag="ACIZE5_000285"
     CDS             32176..33870
                     /locus_tag="ACIZE5_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HGC6107466.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            33836..34021
                     /locus_tag="ACIZE5_000286"
     CDS             33836..34021
                     /locus_tag="ACIZE5_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107467.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            34025..35200
                     /locus_tag="ACIZE5_000287"
     CDS             34025..35200
                     /locus_tag="ACIZE5_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HGC6107468.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            35193..36716
                     /locus_tag="ACIZE5_000288"
     CDS             35193..36716
                     /locus_tag="ACIZE5_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HGC6107469.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            36772..37056
                     /locus_tag="ACIZE5_000289"
     CDS             36772..37056
                     /locus_tag="ACIZE5_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HGC6107470.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            37043..37378
                     /locus_tag="ACIZE5_000290"
     CDS             37043..37378
                     /locus_tag="ACIZE5_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HGC6107471.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            37673..38299
                     /locus_tag="ACIZE5_000291"
     CDS             37673..38299
                     /locus_tag="ACIZE5_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107472.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            39041..39877
                     /locus_tag="ACIZE5_000292"
     CDS             39041..39877
                     /locus_tag="ACIZE5_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HGC6107473.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            39941..40372
                     /locus_tag="ACIZE5_000293"
     CDS             39941..40372
                     /locus_tag="ACIZE5_000293"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6107474.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(40434..41756)
                     /locus_tag="ACIZE5_000294"
     CDS             complement(40434..41756)
                     /locus_tag="ACIZE5_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HGC6107475.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(41910..43550)
                     /locus_tag="ACIZE5_000295"
     CDS             complement(41910..43550)
                     /locus_tag="ACIZE5_000295"
                     /EC_number="4.1.1.101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043883 - malolactic enzyme activity
                     [Evidence IEA];
                     GO_process: GO:0043464 - malolactic fermentation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malolactic enzyme"
                     /protein_id="HGC6107476.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            43883..44353
                     /locus_tag="ACIZE5_000296"
     CDS             43883..44353
                     /locus_tag="ACIZE5_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HGC6107477.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            44575..45678
                     /locus_tag="ACIZE5_000297"
     CDS             44575..45678
                     /locus_tag="ACIZE5_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HGC6107478.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLKDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            45962..46642
                     /locus_tag="ACIZE5_000298"
     CDS             45962..46642
                     /locus_tag="ACIZE5_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HGC6107479.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            46732..47766
                     /locus_tag="ACIZE5_000299"
     CDS             46732..47766
                     /locus_tag="ACIZE5_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HGC6107480.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            47780..48115
                     /locus_tag="ACIZE5_000300"
     CDS             47780..48115
                     /locus_tag="ACIZE5_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107481.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            48099..50579
                     /locus_tag="ACIZE5_000301"
     CDS             48099..50579
                     /locus_tag="ACIZE5_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107482.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWKLTAGPTS"
     gene            50635..52194
                     /locus_tag="ACIZE5_000302"
     CDS             50635..52194
                     /locus_tag="ACIZE5_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6107483.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            52191..53555
                     /locus_tag="ACIZE5_000303"
     CDS             52191..53555
                     /locus_tag="ACIZE5_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HGC6107484.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            53726..54796
                     /locus_tag="ACIZE5_000304"
     CDS             53726..54796
                     /locus_tag="ACIZE5_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6107485.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            54811..55479
                     /locus_tag="ACIZE5_000305"
     CDS             54811..55479
                     /locus_tag="ACIZE5_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6107486.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            55499..56077
                     /locus_tag="ACIZE5_000306"
     CDS             55499..56077
                     /locus_tag="ACIZE5_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6107487.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            56478..57389
                     /locus_tag="ACIZE5_000307"
     CDS             56478..57389
                     /locus_tag="ACIZE5_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGC6107488.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(57477..58394)
                     /gene="rnhC"
                     /locus_tag="ACIZE5_000308"
     CDS             complement(57477..58394)
                     /gene="rnhC"
                     /locus_tag="ACIZE5_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HGC6107489.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            58596..59033
                     /gene="zapA"
                     /locus_tag="ACIZE5_000309"
     CDS             58596..59033
                     /gene="zapA"
                     /locus_tag="ACIZE5_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HGC6107490.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            59092..59640
                     /locus_tag="ACIZE5_000310"
     CDS             59092..59640
                     /locus_tag="ACIZE5_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HGC6107491.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            59755..62115
                     /locus_tag="ACIZE5_000311"
     CDS             59755..62115
                     /locus_tag="ACIZE5_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HGC6107492.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEEQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLYDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            62202..62516
                     /gene="trxA"
                     /locus_tag="ACIZE5_000312"
     CDS             62202..62516
                     /gene="trxA"
                     /locus_tag="ACIZE5_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGC6107493.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            62698..64476
                     /gene="uvrC"
                     /locus_tag="ACIZE5_000313"
     CDS             62698..64476
                     /gene="uvrC"
                     /locus_tag="ACIZE5_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HGC6107494.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            64621..65520
                     /locus_tag="ACIZE5_000314"
     CDS             64621..65520
                     /locus_tag="ACIZE5_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6107495.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            65513..66775
                     /locus_tag="ACIZE5_000315"
     CDS             65513..66775
                     /locus_tag="ACIZE5_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6107496.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            66936..68834
                     /locus_tag="ACIZE5_000316"
     CDS             66936..68834
                     /locus_tag="ACIZE5_000316"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HGC6107497.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(69164..69883)
                     /locus_tag="ACIZE5_000317"
     CDS             complement(69164..69883)
                     /locus_tag="ACIZE5_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGC6107498.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     misc_feature    70073..70120
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF03071"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="sodium ion sensor (DUF1646 type); this
                     cis-regulatory element may regulate processes involved in
                     with the transportation of sodium ions; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF03071"
     gene            70220..70552
                     /locus_tag="ACIZE5_000318"
     CDS             70220..70552
                     /locus_tag="ACIZE5_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107499.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            70539..72542
                     /locus_tag="ACIZE5_000319"
     CDS             70539..72542
                     /locus_tag="ACIZE5_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HGC6107500.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            72561..73031
                     /locus_tag="ACIZE5_000320"
     CDS             72561..73031
                     /locus_tag="ACIZE5_000320"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HGC6107501.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            73052..73636
                     /locus_tag="ACIZE5_000321"
     CDS             73052..73636
                     /locus_tag="ACIZE5_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HGC6107502.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            73651..74637
                     /locus_tag="ACIZE5_000322"
     CDS             73651..74637
                     /locus_tag="ACIZE5_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HGC6107503.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            74627..74938
                     /locus_tag="ACIZE5_000323"
     CDS             74627..74938
                     /locus_tag="ACIZE5_000323"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HGC6107504.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            74960..76741
                     /locus_tag="ACIZE5_000324"
     CDS             74960..76741
                     /locus_tag="ACIZE5_000324"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HGC6107505.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            76734..78110
                     /locus_tag="ACIZE5_000325"
     CDS             76734..78110
                     /locus_tag="ACIZE5_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HGC6107506.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            78117..78752
                     /locus_tag="ACIZE5_000326"
     CDS             78117..78752
                     /locus_tag="ACIZE5_000326"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HGC6107507.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            78782..80137
                     /locus_tag="ACIZE5_000327"
     CDS             78782..80137
                     /locus_tag="ACIZE5_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGC6107508.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(80329..81723)
                     /locus_tag="ACIZE5_000328"
     CDS             complement(80329..81723)
                     /locus_tag="ACIZE5_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGC6107509.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRTQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            81815..82786
                     /locus_tag="ACIZE5_000329"
     CDS             81815..82786
                     /locus_tag="ACIZE5_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HGC6107510.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            82783..83565
                     /locus_tag="ACIZE5_000330"
     CDS             82783..83565
                     /locus_tag="ACIZE5_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HGC6107511.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(83734..84105)
                     /locus_tag="ACIZE5_000331"
     CDS             complement(83734..84105)
                     /locus_tag="ACIZE5_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC6107512.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            84239..84682
                     /locus_tag="ACIZE5_000332"
     CDS             84239..84682
                     /locus_tag="ACIZE5_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGC6107513.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(84725..85534)
                     /gene="yidA"
                     /locus_tag="ACIZE5_000333"
     CDS             complement(84725..85534)
                     /gene="yidA"
                     /locus_tag="ACIZE5_000333"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HGC6107514.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(85553..86920)
                     /locus_tag="ACIZE5_000334"
     CDS             complement(85553..86920)
                     /locus_tag="ACIZE5_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGC6107515.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(86904..87734)
                     /locus_tag="ACIZE5_000335"
     CDS             complement(86904..87734)
                     /locus_tag="ACIZE5_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HGC6107516.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            87897..88334
                     /locus_tag="ACIZE5_000336"
     CDS             87897..88334
                     /locus_tag="ACIZE5_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HGC6107517.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            88410..89030
                     /gene="rpoE"
                     /locus_tag="ACIZE5_000337"
     CDS             88410..89030
                     /gene="rpoE"
                     /locus_tag="ACIZE5_000337"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HGC6107518.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            89219..89725
                     /locus_tag="ACIZE5_000338"
     CDS             89219..89725
                     /locus_tag="ACIZE5_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HGC6107519.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            89742..90641
                     /locus_tag="ACIZE5_000339"
     CDS             89742..90641
                     /locus_tag="ACIZE5_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsiV family protein"
                     /protein_id="HGC6107520.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            90728..91612
                     /locus_tag="ACIZE5_000340"
     CDS             90728..91612
                     /locus_tag="ACIZE5_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HGC6107521.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(91804..91875)
                     /locus_tag="ACIZE5_000341"
     tRNA            complement(91804..91875)
                     /locus_tag="ACIZE5_000341"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(91840..91842),aa:Arg,seq:ccg)
     gene            91935..93269
                     /gene="rpoN"
                     /locus_tag="ACIZE5_000342"
     CDS             91935..93269
                     /gene="rpoN"
                     /locus_tag="ACIZE5_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HGC6107522.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            93418..94509
                     /locus_tag="ACIZE5_000343"
     CDS             93418..94509
                     /locus_tag="ACIZE5_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HGC6107523.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            94550..95551
                     /gene="gap"
                     /locus_tag="ACIZE5_000344"
     CDS             94550..95551
                     /gene="gap"
                     /locus_tag="ACIZE5_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGC6107524.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            95661..96851
                     /gene="pgk"
                     /locus_tag="ACIZE5_000345"
     CDS             95661..96851
                     /gene="pgk"
                     /locus_tag="ACIZE5_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HGC6107525.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLESKELPGLAA
                     INDK"
     gene            96955..97710
                     /gene="tpiA"
                     /locus_tag="ACIZE5_000346"
     CDS             96955..97710
                     /gene="tpiA"
                     /locus_tag="ACIZE5_000346"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HGC6107526.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            97826..99124
                     /gene="eno"
                     /locus_tag="ACIZE5_000347"
     CDS             97826..99124
                     /gene="eno"
                     /locus_tag="ACIZE5_000347"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HGC6107527.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            complement(99447..100022)
                     /locus_tag="ACIZE5_000348"
     CDS             complement(99447..100022)
                     /locus_tag="ACIZE5_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytS/YhcK type 5TM receptor domain-containing
                     protein"
                     /protein_id="HGC6107528.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(100027..101001)
                     /locus_tag="ACIZE5_000349"
     CDS             complement(100027..101001)
                     /locus_tag="ACIZE5_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HGC6107529.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(101025..101069)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            101284..102252
                     /locus_tag="ACIZE5_000350"
     CDS             101284..102252
                     /locus_tag="ACIZE5_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC6107530.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            102349..102642
                     /locus_tag="ACIZE5_000351"
     CDS             102349..102642
                     /locus_tag="ACIZE5_000351"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6107531.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIVDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            102760..102996
                     /gene="secG"
                     /locus_tag="ACIZE5_000352"
     CDS             102760..102996
                     /gene="secG"
                     /locus_tag="ACIZE5_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HGC6107532.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            103099..103854
                     /locus_tag="ACIZE5_000353"
     CDS             103099..103854
                     /locus_tag="ACIZE5_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HGC6107533.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            103857..106214
                     /gene="rnr"
                     /locus_tag="ACIZE5_000354"
     CDS             103857..106214
                     /gene="rnr"
                     /locus_tag="ACIZE5_000354"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HGC6107534.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            106236..106700
                     /gene="smpB"
                     /locus_tag="ACIZE5_000355"
     CDS             106236..106700
                     /gene="smpB"
                     /locus_tag="ACIZE5_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HGC6107535.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            107002..107721
                     /gene="atpB"
                     /locus_tag="ACIZE5_000356"
     CDS             107002..107721
                     /gene="atpB"
                     /locus_tag="ACIZE5_000356"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HGC6107536.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            107774..107989
                     /gene="atpE"
                     /locus_tag="ACIZE5_000357"
     CDS             107774..107989
                     /gene="atpE"
                     /locus_tag="ACIZE5_000357"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HGC6107537.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            108080..108604
                     /gene="atpF"
                     /locus_tag="ACIZE5_000358"
     CDS             108080..108604
                     /gene="atpF"
                     /locus_tag="ACIZE5_000358"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HGC6107538.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            108591..109133
                     /locus_tag="ACIZE5_000359"
     CDS             108591..109133
                     /locus_tag="ACIZE5_000359"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HGC6107539.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            109156..110712
                     /gene="atpA"
                     /locus_tag="ACIZE5_000360"
     CDS             109156..110712
                     /gene="atpA"
                     /locus_tag="ACIZE5_000360"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HGC6107540.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            110726..111628
                     /locus_tag="ACIZE5_000361"
     CDS             110726..111628
                     /locus_tag="ACIZE5_000361"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HGC6107541.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            111651..113057
                     /gene="atpD"
                     /locus_tag="ACIZE5_000362"
     CDS             111651..113057
                     /gene="atpD"
                     /locus_tag="ACIZE5_000362"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HGC6107542.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            113071..113493
                     /locus_tag="ACIZE5_000363"
     CDS             113071..113493
                     /locus_tag="ACIZE5_000363"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HGC6107543.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            113962..114192
                     /locus_tag="ACIZE5_000364"
     CDS             113962..114192
                     /locus_tag="ACIZE5_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HGC6107544.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            114289..115590
                     /gene="murA"
                     /locus_tag="ACIZE5_000365"
     CDS             114289..115590
                     /gene="murA"
                     /locus_tag="ACIZE5_000365"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGC6107545.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            115603..115779
                     /locus_tag="ACIZE5_000366"
     CDS             115603..115779
                     /locus_tag="ACIZE5_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGC6107546.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            115914..116210
                     /gene="yidD"
                     /locus_tag="ACIZE5_000367"
     CDS             115914..116210
                     /gene="yidD"
                     /locus_tag="ACIZE5_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HGC6107547.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            116274..116741
                     /locus_tag="ACIZE5_000368"
     CDS             116274..116741
                     /locus_tag="ACIZE5_000368"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6107548.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            116826..117710
                     /locus_tag="ACIZE5_000369"
     CDS             116826..117710
                     /locus_tag="ACIZE5_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGC6107549.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLIGAAANYLAVRQGEN"
     gene            117824..118060
                     /locus_tag="ACIZE5_000370"
     CDS             117824..118060
                     /locus_tag="ACIZE5_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HGC6107550.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            118148..118228
                     /locus_tag="ACIZE5_000371"
     tRNA            118148..118228
                     /locus_tag="ACIZE5_000371"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:118182..118184,aa:Tyr,seq:gta)
     gene            118235..118306
                     /locus_tag="ACIZE5_000372"
     tRNA            118235..118306
                     /locus_tag="ACIZE5_000372"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:118267..118269,aa:Gln,seq:ttg)
     gene            118432..118602
                     /locus_tag="ACIZE5_000373"
     CDS             118432..118602
                     /locus_tag="ACIZE5_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107551.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            118822..119529
                     /locus_tag="ACIZE5_000374"
     CDS             118822..119529
                     /locus_tag="ACIZE5_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6107552.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRRDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(119588..120232)
                     /locus_tag="ACIZE5_000375"
     CDS             complement(119588..120232)
                     /locus_tag="ACIZE5_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HGC6107553.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKNFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSANHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            120359..120646
                     /locus_tag="ACIZE5_000376"
     CDS             120359..120646
                     /locus_tag="ACIZE5_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107554.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            120754..121074
                     /locus_tag="ACIZE5_000377"
     CDS             120754..121074
                     /locus_tag="ACIZE5_000377"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC6107555.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIA
                     LIGE"
     gene            121155..122468
                     /locus_tag="ACIZE5_000378"
                     /pseudo
     CDS             121155..122468
                     /locus_tag="ACIZE5_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            122465..123184
                     /locus_tag="ACIZE5_000379"
     CDS             122465..123184
                     /locus_tag="ACIZE5_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HGC6107556.1"
                     /translation="MRCSCCGKDIIQNLTFSEIIGVSKSRLPQTCSVCRAQFHLLEAK
                     GCAGCQKPIHLKYEETKKKANTSFVYCNDCQEWKKKYPAYDFQHRAFFTYDEKMQAWI
                     NRYKFMGDIRLAGTFAYKWTQIKKDYPAYIYCPIPLSEKRWLERGFNQVSEMLKAAKI
                     PFQMLLKREQHLLAQAKNTRKERLEMPQPFELAVPLSKIQHKKILIIDDVYTTGQTLF
                     HAADCLQNAQPKIIRTISLAR"
BASE COUNT        40820 a        21121 c        25623 g        35643 t
ORIGIN      
        1 ttaaataaat aggaacaaaa aaattaaatt atttaataca cacattaggg atcattcatt
       61 gaaggattag aagacaacga ggatggcgaa aaatatgatt acaatagaaa agtcgttcta
      121 aaccaatcag ttcctagtat cacacaacgc aagccagtcg atttggtgag attagaggag
      181 tgaaagcaaa ctttattata taagaaaaaa tattcgaaag ggatgctagt ttaggtacta
      241 gtgctgatag attaatatga tgcctcgtaa tattaggcgt agttactcta gagacatcac
      301 tatggactat gatttgtctc agagtcacaa catgtttttt tatgaaaaga aacagctaaa
      361 ataattaaat tgcgcaatgt ttaaactttc ttaaactata acctaataaa tgtgaagaaa
      421 taatgcacaa tttcttcaca tttatcttct attctatata cataccaacc aacaacccta
      481 tatacttttt catttttact cctcaagtaa aaataactcc tagaccgcgg ctacccaccg
      541 cggtcgtttt tttattcttc aatcaaaatc gctttgatac ccaaacctgc caagattcgg
      601 gcagaagtat aagtattcaa tcctcttctg aaagtaatgt aaactttttt atcttttggg
      661 atttcattga ttcgatctcg taactcattc attggaatat tttttgttgc cgagatactg
      721 ccagaaggtg ctttattagg ttcacgtata tctaaaaaga acgcttcttt caaatcgttt
      781 tcgggtatat cacttgcttt gatcgtttct acgatattcg tcatttgatt gattgcgaca
      841 taaccagcta tattcaacgg gtcacgggta gtagaatacg gtggagagta aggcaactcc
      901 aaatcaggca aatcaaagac tgtcaagttt ccggtgattg ctacagaaag ttctcccatc
      961 cgtttatcga cacctttttc tccaaatgct tgtccaccta aaatacgacc gctatctgca
     1021 tcaaaaatca gctttagatt taatcttgta gcttctggat agaaataggc atggtcaaag
     1081 ggagtgataa aaacagtttt ataatttgtt atgcctgatg cttttaattc atgttctgtc
     1141 attcccgcat aacttgctgt atgatcaaag atttttgcga cacctgcacc aatatatccg
     1201 cgatagcgca taggcgtacc atttaaaata tctgccagca tatgtccttg acgattggcc
     1261 gcactggaaa gcatactttg gatcggctga ccagtcacta cactagtcgt ttcgataata
     1321 tcgccaatcg catagatgtc cggcagattg gtttgtaact ggtcatcaac aatgatctga
     1381 cctgtatctg ataattgtat gccggttgct ttcaccactt cattcttcgg agaaacacca
     1441 acagcaaaaa ttagcatatc agcagaaagg acggagccat ctgataatac tatttctcga
     1501 cctttatcac ggatctcagt aactcttgtt tctaaatgaa cggctaatcc ttctttcagc
     1561 aatttgtcat aaactaaatt agcaatttct ggatcataag ggaaagcgac ttgtggcaat
     1621 tgatcgatta aagtcacgtc taagccgcga tgcttgaaat tctcagctaa ttccagaccc
     1681 ataacacctg caccaagaat gacgacatgt tgtggatttt tttcttcaag gaacgatttg
     1741 attcgatccg catccgtcac actacggagg acaaagccgt tttctgcttc aaaaactccg
     1801 ggaatatccg gataatctgg tctagcacca gaagagatga tcaacttatc gtaatctgtt
     1861 tttatttctt catttgtgga taggtcttta actgttaatc gcttagtaga aggatcgatt
     1921 gctgttactt cgtgtttagt aaagacatcg atgttgtttt ttgttttcaa tatttctggt
     1981 gtacgttcga tcagcgagtc acggtcagtg atcacacctc ctaaataata aggcaaagca
     2041 caacttgcat aagaaatatt ttctccgcgt tcatagataa tgatttcgtg cgcttcattc
     2101 aatcgacgga aacgagtggc aaatgaagga ccgccagcta caccgccaat gacaacaact
     2161 ttcataaaaa catctccttt tctacgttga tcgtactatg ttatggtaaa aaacagcaaa
     2221 taattgtgcc ggaaaattat tgtttatttt gaatagacag aaaatataga gaaataattt
     2281 gtggataaaa cctaaaaatt tttttctatt ttaaggatag ataatacttt gaaggggata
     2341 accctgtata ttttttaaaa gctgaagaaa aatgatggat cgaatgaaat cctaatatat
     2401 ctgcaatttc tgtataggtt aattcatttt ctagcacgag acgttttgct ttttccattt
     2461 ttagttcttt aaaatagcta ataacacttt ttccattcac ttttctaaaa tgttttttta
     2521 agctggctgg actgataaaa aaaatttggg ctaattgttc aagcaaaaaa ttttctgaaa
     2581 gatgttcttc taaatatcgt atgattggat caactaattc atctgaataa agaatatgct
     2641 tttttttagg aatgactttc tcatttgaag gtattgtcaa taaagcaagt tcctgttgat
     2701 aatgccttgg taaggaagac aattgaattt tttgcagaca ataagtaact aataaggaaa
     2761 gcaaatgaat gctcatctgt tggcatagta tgaaaaaaga attgatttcc tgatcatagg
     2821 aaatagctgg cttactatgt tttagataat caattttgaa ctgttcattt ttcagaaaag
     2881 taatgataga tgttatttct tgatctatag aaaaagattg tcccgtaata tgtgctaata
     2941 attgctcatc aaaataaaac tggataatga taaaagtttg tgtttccttt tgagtagaaa
     3001 agatttggac ttcttgctgt ttatcaatga ataaaaggga aggattatct agttctatag
     3061 atttatgtgc aaattcagca tataaattag cgctttcatt tattagtagt cgaaaatagg
     3121 gagcagcaga taaatgaaga tgggtatcta tggaataggt tagtgttttt ttgacaagat
     3181 tggaggattg gttgtttgtt aacaaaagaa ccactttcct ttctcttttt atataaaaag
     3241 ctttctattt ataattaatg actattataa caaaaatgaa aagccaaaac gacaagtaaa
     3301 atattttttt atataaatat ttgtgttact aattccgtta atatacataa gtgaaagcgt
     3361 tttatataag aacttgaaaa gaaagaaggg atagacatga aaaaaagata caaattggtg
     3421 atagctttgc taaacattac cctattattc agcttaagtg catgtggaaa aactaacgaa
     3481 gaagtaacag caaacatcgc agatccaatg ataaaaaaag ccactacatt agaagtatat
     3541 gtcgcaaacg gcaaactgac aaactatgtt gaaaatgctg caaaaatcta taaccgcaaa
     3601 actggagcaa atattgactt aaaaattgtg aatgtagctt cgggaacagc aacagtacaa
     3661 atgatcaccc caaaattggt aacacacgaa gatatgccgg atattatctc catggcagac
     3721 acttcagcag caggtgtgct ggaaaaattt caagatgctt tttatagtgc tgatgaatat
     3781 ggattttatg acaaatatgg cgatcagttt tatgatcaaa aattgaatat tttgcgtcaa
     3841 caaacgagta atgaaacgat tattccttgg gctagtgatt ttaccccagc actttgttat
     3901 tatcaaccaa aaaaatttgc tgaaataggt gtagattttg aagaaatcag ttcttgggaa
     3961 gaatatatcc aggtggcaaa agcattaaaa gaaaaaactg gtagttttgg aattgccttg
     4021 ccagaatctg gggaccaaga attgtttatc aacatgctag cccagcagaa tcaatctttg
     4081 cttgatgaag aaggaaatat ccgtctgaat actaaagaag cgaaacatgc tgcaaagtta
     4141 atcaaagaaa tgatcgactc agatattgta catttctacg gtgcacaaga tgctgagaaa
     4201 gcatttcaag aatctgcaat gtttgttgct ggcggctggt atgctacgaa tatgtctttg
     4261 aattttcctg atgcatctga caaatggcgc atggctccac tgattccttt ttcaaaagaa
     4321 aatccaggaa aaggtgcagt atcaggagga tcaagttttt atgtccctaa agatgcaaaa
     4381 aatccacaag tggcacaaca atttcttaca tttatgctga cagatgaaga atgcttagcc
     4441 aacgcactgg agctgggcgt ggctacatct aactcattgg cctatcaaac agaagcagct
     4501 gagaaaaagt ttgactacta aggaggacaa aaatactatg aactattgaa taaaatcaat
     4561 gaaaatacat caaatactgt tttaccagcc acttattcag atgctacgtc ttatttgact
     4621 accgctgcat ataactattg gcaaacaggt gattttgaaa attcatatct aaaagaagca
     4681 gaaaattttg ctcataagta cggcgtaaaa ttaactggtg attaaaaaat attaggagga
     4741 cttaacgatg atgcaatctt cgttaccaag caagacaata aagaacagca agaaaaaagc
     4801 aacagatacg tctcataaaa aaagtgctta tggattggtc acaccttttg ttattttctt
     4861 tattgtgacg attttgattc ccatcattat ctcgtttgct tttagtttta tgaaaattgg
     4921 ctactcattt gaatttgttg gatttgacaa ttatctagct atcttccgag atccattgtt
     4981 tattaaatct tacacgaatg ttttgattat catggcagga tcaattccaa taacgatgct
     5041 attagctatt tactttgctg ttttattgaa ttcagcacag ttaaaaggaa aaggattttt
     5101 tagaactgtc tattatattc caaccattac atcaacggtg gctgtagctt ccgtattcat
     5161 gacttttttc aatccgactg ggttattcaa tggatttttg aatgcgctag gaattaacgg
     5221 tgtacagtgg ttaacaaatc ctttttggat acgaatatca atgatcatca cgatgatttg
     5281 gcttagtgta ggatataaca ctattttatt tttagctggt cttcaaggga tttctaaaga
     5341 gatatacgaa agtgctgaaa tagatggagc atcgaaattt cggcaattct ttttattaac
     5401 gatccccatg ctaaagccaa tcattttaat ggccacagtt ttagccacta tcaatggctt
     5461 gggtaatttc aatatcccaa atatattctt tgggacttcc aatggaccag aaaattcagc
     5521 tttggtcgta ggagtcaatt tatataaaac aagttttgaa atggttgatt ttggaaaagc
     5581 ctctgctatt gcctggacga tggtgtttgt atctgttata ttatcggcta ttcaatttaa
     5641 attcggaggt gataaaaatg actaaacaaa agatacaaag cagaattttt acgtacgtca
     5701 ttattgtgtt tggtgcctta atatttttga tgccatattt atatatgatt gtagcttcaa
     5761 cgcaaagtaa tcaagaaatt ttaagtggcg gaatcaattt caagtttggg gatatgctat
     5821 taaaaaactg gcaagccatc atggcgagat ataattatcc cttgattatt tggaattcga
     5881 ttgttattgc tgtaatcagt acagttttag ctacagccag ttctacaatg gcgggttatg
     5941 cattagcaaa gtatcgtttt atggggaata aactgttgtt caatacagtt atgctatcta
     6001 ggatggtgcc tttttttacc acattgattc ctttatttta cattatgagt cgtttaggat
     6061 tatcgaatac ttatgcaggt gtgatcatcc cttcgattgc cagtacaact tcagtgttta
     6121 tgatgcgaca atatagcagt caatttccta cagcactgat ggaggctgcc agaatcgatg
     6181 gtgccaatga gtgggtgatt tttacgaaaa tcgctgtacc gattttatca cctacgatta
     6241 ttactagtgg tttacttatc tttatgggaa gttggaatca atatctattt ccattagtca
     6301 tgctttcaga taaagataaa tatacggttc ccttaattat caaaaatatg acggtttcta
     6361 gtacaggtga gccaattaat tatggcgcaa ttatgctaat tttagcaact tcagtgatcc
     6421 caatggtctt gatttatgtg tgggcgcagt ctaaatttaa ggagaatgac attggagctg
     6481 caaataagta aaaaaaataa cgaatgttaa ccatctagtt cgttctagga gcaactccac
     6541 attcataaaa attaaaagaa tggcgggata tccatgaatg aacagacgaa ggaatggtca
     6601 agaaaaattt tgaatgtagc ttctgaaaag atagatgcgg aattagacag aatggggaat
     6661 aaaattccat atatttctta caacggaaaa tatacagacg taataaagga cagaggaatc
     6721 gactggtgga ccaatggttt ttggagtggt attttatggc agctctttca caagacaaaa
     6781 cgagaaaagt tcaaagaggc agcaatacaa caagaacaat tattagaatc tgccctgtac
     6841 catttttcag acgttcatca tgatgtaggt tttttattct taccatcggc tattgcacat
     6901 tatcaacagt ctcaaaacaa acatagtcga caactagggt tacatgcagc tacggtactt
     6961 gctggacgct ataatatttc agggaactat ttagtagcat ggaatgacca taaacctggt
     7021 tggatgatta ttgatagtat gatgaattta ccattactgt attgggcttc gagggaaact
     7081 ggtgatccga ggttctctaa aattgctcgg cagcatgcag atacaacagc taagtatcta
     7141 gtgaggaaag atggatcaac cgggcatatc gcagaatttg atgcagaatc agggaaatat
     7201 attcggttac ttggcgggca aggatacaat gagaattctt gttggagcag aggaaatgca
     7261 tgggctttat atggattcgc gttaagttat cgttacacaa aaaatccgta ctatctagct
     7321 atagcagaaa agatagcagt aaattttatt cagaaaatcg aaaaaactgg ttatattcct
     7381 ctcattgatt ttgctgtaaa agattcgaat attgatacca gtgctggagt atgcgctgca
     7441 tgcggtcttc tggaattagc aggatatgtt tcctctgtac gatcaaaaat gtatcatgaa
     7501 gctgctatca atatactcca aaagacagaa aagcactatg caaattggaa tatggatgaa
     7561 gatgggatca ttggaggcgg agcagaagca taccatagag aactgactta taatgtgcca
     7621 ctgatctatt ctgattattt ttttattgaa ggcttacttc gattagaaca gtcggaatta
     7681 gctatttggt agtaaaaaga ggagaaaata caatgaaaca tccagtacca ctattaagga
     7741 ccagacagga ttactttgac ttatttaaaa agataaatca accactccag ccgttttatc
     7801 gagcaagtgg cgcacaaatt gattatatac atcaaggggt aggatatgga aataaaattg
     7861 caggaatgga aggattctct cgggttttat ggggagcggg gcccgcaatt gaccaattag
     7921 atgaacgatg gttgaaatta attctatcag gaataaaagc tggaacagat ccttcccatc
     7981 ccgattattg gggagaaata catgaaagag accagcgtat ggtagaaatg cccgcaatgt
     8041 tattagcgtt atatcatcat gaacaattat tatggaaaaa attagataca ggagaaaaaa
     8101 gccagattat tcattggttc tcgcaaattt ttgaatatga atgtgcagat ggtaattggc
     8161 aattttttaa gataattgtc ggaacaatta tccaaaaatt tggttatcca gttaaagaat
     8221 cagcactgaa agaagcattt gataatatag aaaattgtta tcttcaaaat ggctggtatc
     8281 gagacagttc aagaggtcgc caagattatt ataatccttt tgcatttcat tattatggtt
     8341 tgatttatag cgtactagaa ccagaaaagc ccattagcca gatatataag aaccgagcta
     8401 ttgatttttc tagagactat attcattttt ttgcggaaga tggtgcaaat gtgccttttg
     8461 gtcgaagcat gatttatcgt tttgcagttt caagcttttg gtcagctatg ttgtgggccg
     8521 atcttttgcc ttttaaatta ggtgaaatca aggggttagt caatcggaat ataagatggt
     8581 ggatgcaaaa agaaatattt gatgaaaaag gtatcctgaa tattggttat acctaccctc
     8641 aattgacatt gactgaaccc tataatagta cgttatctcc attatggctg aataagattt
     8701 ttttattgtt ggcgctacct gaagaccatg agtattggac ggctaaagaa atgcctatgc
     8761 ctattcgtga aggaactaaa cttctttcag aagccaattt gctcatacaa catgataatg
     8821 gacatacatt ttttttgaat gcgggacaat tagggccaaa tttccataca ttgaccaatg
     8881 aaaaatattt aaaatttgct tattctagtc aatttggttt ttcgataccg cgagcgaatc
     8941 aattgaaagc agaaatggca atggattcaa tgctagggat tcagcgagcg gacacatata
     9001 tcacgaccag ttttaagaat gagagcatca aaacctatgg acagttcatc gttcgaaata
     9061 atgtacgaga cattgtatgt aagaaagagg tacttgcctc tacatgggaa cctactttac
     9121 aggcaaaaat cagaacttgg cttattcctt ttgaaggctg gcagattcgc gtacacaaag
     9181 tagaattaga tacagaatat gttctatatg agacagggtt tgctattgaa tgttctcctg
     9241 agaaagaagg aataatcata gaagaagaca aggaaaacta tagggtgagt gaagctggct
     9301 tttcaggtat tatctgttta agtgacgata ctattaaacg aaaatccaca gctattatgg
     9361 gtttgcccaa tacaaacttg atgacatggg aaaacacttt tattcctgga ttagagggta
     9421 catttggaaa aggaacccat tggctcggaa caggagtggt tgctcatcaa gatcgggatt
     9481 atagtttaga agtatggaac aatcgtccca aaattgattt tgatgggaca accgggctaa
     9541 ctatccaaaa taaaaacaat aaaaaaagac taaaattatg ctaaaggctg gtggggaaat
     9601 gcttgataaa gtgatgtttg aagagataat acatccagaa aaatggataa atgaatgtta
     9661 taaagaatta atggaaaaag aatggaataa tgagatcgag cgttgtcgca gacacacgga
     9721 gaggttaatc aaacgtatca gtaacagtca gtatcaattc ccaagcgagt gtcctataaa
     9781 aggacgttat ccattaagag acaatattgg ttggacagaa ggattttgga caggaattaa
     9841 ttggttgtta tttgagaaga cgggtgatcc tttatttcaa caaacagctg aaaaagcaga
     9901 tatagatttt atccacagga ttgactgtca aattatcact aatcatcacg atcttggttt
     9961 tttgtattct ttatcaaccg tagcagatta taaaataacg ggaaatcgaa aaatgaagga
    10021 agcttcaatt gatgctgcag aaacattact tcagcgtttt tgggagaagg caggagttat
    10081 acaagcttgg ggagatccta gtgatccttc acaacaaggt agaatgatca tggattgttg
    10141 catgaatctt ccattattgt attgggcgag tgaagaaact ggaaatcaaa aatataaaaa
    10201 agctgctcag gctcatattc aaaatgcagc agattattta gtaagagaag atggttcaac
    10261 ttatcataca ttttatatgg atgtcaaaga tggaaaacca agatatggaa gtacgcatca
    10321 aggttatagt gataattcct gttgggctag aggccaagca tgggggattt acggttttgc
    10381 attaagttat cgttatttga aagaacaaaa atattttgat ttaagcaaaa tattagccaa
    10441 ttattttatg aatcggttgc cagaagatac catttgttat tgggatttga tctttgatga
    10501 ttctagcaga gaagaaaaag atacatctag tatggtgatc atggtttgtg gattattaga
    10561 attaatagaa tcaggtctat tagacaaaac agaaaagaac ttataccagt ctgctgtttg
    10621 gaaaattatg cgacaattga aagaaagata tgctacaacg gaagaagaag atggcttttt
    10681 aacacagtct gtttataata agcccaaaaa taatggggta aatacacctt gtatttgggg
    10741 tgattactat tatttagaag ctttagtgag aatgactagt aattggtctt cttattggtg
    10801 aaaaaggtaa atatggaatt tttgtttgat aaaataaaaa aagaaaaacc aaaacagcat
    10861 gaatggtttc tgttttggtt ttttcgttaa ttttcatatt cttctaattc caagcttagt
    10921 tcttcccatt ccgtcaattt tgtttcttga tcttgtctag cagcttctaa atcttggttc
    10981 agctcattga gttttacgtg atcttccagg ttttctggcg cgaccatttc ttgttccaac
    11041 tgatcgatcc attcatcgat ccgcgccatt tcttcttcaa cctgagtaat ttttcgttga
    11101 aggctacgga taagcttttg ctgttctttg ctttggtaat aatcagattt gttcgtggga
    11161 gcaggagcag attctggctc atcttgtgcc aacaattcgg cgatttcttc ttcttcctgc
    11221 tttttctcta aataataatc atagtctcct agatagactt tgctgccatt ttcagagagt
    11281 tcgacgactt ttgtcgcgat ccgattgatg aaatatcggt catgggaaac aaaaagcagt
    11341 gtgccgtcat aatcgatcaa tgcattttct aatacttctt tgttgtcaat atctaaatgg
    11401 tttgttggtt catccaaaat caaaaaattt tctttgttca tcgctaactt ggctaaagca
    11461 acccgtgctt tttcaccgcc acttagcaga gggattggtt tttctacatc ttcgccagaa
    11521 aataagaaag cacctaaagc acttcggatc tctttttctg gagtggtagg atgctcatcc
    11581 cacaattctg ctaggatcgt cttgtttgta tgcagatcag cttgaccttg atcgtaatag
    11641 ccgatggtga catttgtccc tagcgtttct tttccacgga taaaagggat ctggtgaatg
    11701 attgatttca gcaacgtcga tttcccgata ccattcggac ctactagagc aatcgcttct
    11761 tgacgacgga tatctagatt gattggttca gataaggtga cattatcata tccgatagcg
    11821 gcatcttcga tttgcaagac tacatttcca gaaggctttt ctatactgaa tagaaagttt
    11881 gcttgttttt catccccttg aggacgatcc agccggtcca ttttttctaa tgtctttctg
    11941 cggctttgcg ctcgttttgt ggtagaggcg cgaacaaggt tccgagcaac gaagtcttct
    12001 aatttatgga tttctgtttg ctgcttttca taagccttcc attcacttgc taactgttct
    12061 gctttcaaat ctagatattt cgaatagtta cctttgtaat ggcgcatttt tcttctgctt
    12121 aattcataga cttcattgac tactttatct aaaaaataac ggtcatggga aacaatcaat
    12181 aatgcaccag tatagctttg cagataattc tcaagccagg aaagtgtctc gatatctaaa
    12241 tggttcgttg gttcatctag aatcaaaatg tcagggtgtt gcaaaagcat gcgagctaaa
    12301 gctaaacgtg tgcgctgtcc gcctgataaa gtatcgattt tctgatcata aaatgaagaa
    12361 tcgaatttaa acccatgcaa tacggaacga atttcatttt cataaccata gccgtttcga
    12421 tctgaaaaat cgtgttgcag ccggtcgtat tcttttaaat aagaactata agcaggtgtg
    12481 tctggcgtac cttcgctaat gaaaatctct agctcgcgca tccgctcttc catttgtcta
    12541 acttgttcaa aagctttcag catctcgttc caaactgttt cattggaatc aagtcctgtg
    12601 tcctgagcga ggtatccgag agtcgctgtt ttatttttag cgatctttcc ttcatcaggt
    12661 gcttcaattc cagcaatgat ctttaataaa gtcgattttc cagcgccatt tctgccaact
    12721 aaagcgacac gagcgcctgt actgatttct aaatgtatgt tttcaaataa gacttctgca
    12781 ccaaaatggc gagcaatctg attggcttgt aataatatca tggaatcctc ttttctactt
    12841 tgtgaattct cctcaaataa aaaactattt ttcaattagt agtctaccat aaattccatt
    12901 atactgcgag atttgcagaa atgataaata aatgaataaa gaataaaatt tcacaatatc
    12961 tgagcaatgg aattgatttt ttcctataaa tactgctatg atggagaaat caaagatgta
    13021 attagacaat acgtggaggt catttcgtga aagatcatat tattccaaag gcgacagcta
    13081 aaagactgcc tttgtattat cgctatttaa ggattttaaa taatgctgga aagaaaaaag
    13141 tgtcttcaac tgaattaagt gaagccgttc aagtagatag tgcaacgatc cgtcgagatt
    13201 tttcttattt tggcgaatta ggaaaacgtg ggtatggtta tgatgtagaa gatcttatgc
    13261 acttttttgc aaagacatta aacgacgatc aattgacaaa tgttgcgctg atcggtgtag
    13321 ggaacttggg aagtgcttta ctaaaataca aattccatca aagtaatagc atacgtatca
    13381 gttgtgcttt tgatgtgaat gaggaaatcg ttgggcgcat cgtagacggt atccccgttt
    13441 atccaatgga agatatgtca gaacaaatca agatccaaca aatcgaagta gcaattttaa
    13501 cgatacccgc tgaaagagca caagaagtag tcaatcagtt aacggaagca ggaatcaaag
    13561 gaatcttgaa ctttaccgct gctcgattga atgctccgtc agatgtattg atccaaaatg
    13621 ttgatttgac gaatgaattg caaaccttga tctatttctt gcattctgac gcaaatgcgc
    13681 attccgaaaa tacagcagaa taaaaataaa aagcgattga acaaatgaag gcaaaacttt
    13741 cacttgttca atcgcttttt tctgtttgga caacgattat tttgttcgga agatttcttc
    13801 ataagaaagg gaatcatctt ctgctgtcag ttcatctagt agataacgga tttttttaaa
    13861 gtcgatgaac cgtgcttgcc gaaagacttc ttttccttga tgaaaaatca ggacaactgg
    13921 cgcagtcagc acttcaaatt tactagctac ttctggtgtt tcaaatgcat ccaaatgaag
    13981 tgccggaata tcataatgtg tgagaagttc ctctagtcgt ggacgaacag cgtgacaaac
    14041 actgcaatta ggcatcgaaa gataaatgac ggcaacggat gactgttgca gtatgtcttg
    14101 aacttcagtc aagttagtgg tttgtttcat ttttattctc ccttttatga tagaagtgat
    14161 atgtatgaga ccttaattta atgggaataa cagaaaaagt caattgaagt gctttggtaa
    14221 aaaataagag ttgtgtaaaa atttacagag caacttgttt tttttgaata aaagcgtata
    14281 tttgcaaagc gaatgaacta gaaataaaaa ggaggaaact catgttttct tttattccaa
    14341 attcggtttt gcagatgagt acgattttct tatcgatcgt tattgaagca ttacctttcg
    14401 tattattagg ctgtcttatc tcaggcgcct tacaagtatt tttgacccca gaacgtgtga
    14461 agagatggct tcctgaaaat cgtatcttct ctatttttac tggttcgatc ttaggatttt
    14521 tctttccttc atgtgaatgc ggcatcgtac cgatcgttca tcaatttgtt aaaaaaggcg
    14581 taccagttca cacagcgttt gcttttatgc tgactgctcc gatcatcaat ccaatcgtga
    14641 ttttttccac ttttatcgca tttggcaatt cttggcagat ggcaagctgg cgggtgatag
    14701 gcagcttttt tgttgccctt gtgattggtg tctggcttgc ctattttcaa aaagacgctg
    14761 tattgaaaga aaaaatcacg tctaaagtag cagaaaatca ccatcatcat gtccatgaag
    14821 aagaacaaag tgagaagaat gaaccaaaaa atcagctgat ccatcaaact gggcatgtgt
    14881 tgacacattc aatcgacgaa ttttttgata caggtcgtta tttgatcatt ggcggattaa
    14941 tcgcagctgc gatgcagact tatttaccaa ctagaattat gctaacgctc ggctcaacaa
    15001 agattttagc cattatcatc atgctgttat tggcctttac gatgtctctt tgctcagaag
    15061 cagatgcgtt tataggatct tctttgttaa gtctgttcgg cacagcacct gtagctgcct
    15121 ttttggtctt tggcccaatg gtcgatatca aaaatctact gatgatgaaa cgatatttta
    15181 caggacgctt tattttatcg ctgatcggac tgattgccct tagcgttatt ggattcacat
    15241 tatttattta ggagggaaaa tatgctgcgg tttttgattt tatctgggta tttcgaattg
    15301 atgatgtact tgcaagtttc tggcaaactc gatcaatata tcaatgtcca ttatcgctac
    15361 ttagctattc tttcaatgat tttatctgct cttttggctt tagttcagct gtatttgtgg
    15421 gtcaaaaacg gaaaagcaga agaaaaggca cacgagcacg atcatgacca tgggttgtca
    15481 aaaccttatc aacgtggaat cgcttatgta ctgctagctt tgccagtaat cgtggggacg
    15541 ttgtttccaa cagttagtct cgacactacg atcgtagaag ccaaaggatt taatttccca
    15601 gtaagtaaag aatcagtagg ggatccggag atgcagacac aatacttaaa gccggatacc
    15661 agtatttatt tcaacaaatc agactactta gaccaaatga atgagttgaa agaaaagtat
    15721 ggggataagc aaactatcaa gatcacagat gaaaactatt tagaagttat ggagctaatt
    15781 tataattacc ctagcgaatt cattggcaaa aaaatcagct atgaaggatt tgtttaccaa
    15841 acaccgaacg atagcaatac agatatcttc ttgttccgat tcggcattat ccattgtgtg
    15901 gcagattcag gagtctttgg tttgttgacg catatgccgg aaggagtaac ggttaaaaat
    15961 gatgaatggt ataaaataga aggaaccatc caatcagact attatcaacc attcaagcgt
    16021 gaaatcccat ctgtagttgt tacaaacgct gagaaagtct ctgctccgaa aaatcagtat
    16081 gtgtatcgtt ctttttaaaa gaacaaaata aataaacata gctcagacag ctgacacgca
    16141 aggacgtcgg ttgtctggct ttttttgcat gatgtattca tttgtttgat atttatttta
    16201 gaagcagcat cctgaaagta tttgatatcg gtttcaaagg tgttggaaaa gattgtgaag
    16261 agaattacaa tttattccta acatgtatgt tgaaaagttg tatgaaatga ttttgatagt
    16321 aaaatatcga gtggaggtac tttttatggt aacgcgtata tttattttgg atgatagttt
    16381 ggtttttgaa aaaatgctag tagaaatttt ggaagaatcc agaattttat taagtccttg
    16441 gaaatttgag atcgttcagg gattgaacgt tatacaattt gttgaattca ttaaaaataa
    16501 tgaaatctat tcctcagata tttttttcct agacatcgat ttgaacgcct attatagcgg
    16561 tatcgaacta ggcgaaatgc ttagagaaaa gaatgaaaag tgtaaaattg tttatctaac
    16621 gtctcatccg aataaagcaa taactgttat taatcgaaag attacgccta gtggttattt
    16681 gataaaagaa ttcacttatg aaaaaaataa aaaaagcatc caaagttact tattgaaaga
    16741 aaaagaaaac tatcctgttc aacatgctac gaaaaaaagg tggacaactg tccgttatgg
    16801 taatagcgat cactatatcc attacgatga aatcctttat ctaatgagca tgccaggtta
    16861 taaaaataaa ataggcctag tattgaaaga tgaagagatt ctcgtaaacg gcacaattaa
    16921 aaaatataaa aaatcactcg aatatgagta tttatgtaaa gatttaaaag cttatatcat
    16981 taatactgaa aacattacat ctattagcag agtaaacgaa atagtaacat ttgcaaatgg
    17041 agaacaacta gagatgggaa agagaagtat tgataaacta aagaatttta tgcaagaaaa
    17101 gatagaaaat gaatcatttt aaagaaaaca aagactcata tcttacctgt tagaagagtg
    17161 ttttcctgta gaagagaaca acccaagtag cagcctagtc gtttctatcc ttttttgtta
    17221 tgcactcttt ttgacattta ctccaccaat aacgaagggt acaataaaaa gtaataacaa
    17281 acaaaaggag tacagaaatg attgaattca tcaatgtaag taaaagttac gggaaaaaac
    17341 aagcattaaa agacttgtct ctctcgataa gacaagggga aatttttgga tttttaggac
    17401 ataatggtgc cggaaaatca actacgatta aaagtttagt tagtattatt gaaccatcat
    17461 cgggaacgat tttagtagat ggaatgaaat tgacggaaaa tcgattgagt atcaaacaaa
    17521 aaatcggtta tgtgcctgat tccccagata tttttttaca attgacggct ggagaatatt
    17581 gggacttgat ttcagctgcc tatgaattag acacacaaaa aaaagaaaag cgtttagcag
    17641 aattgacagc gctttttgat atgtatagtc atcaaaatga aacaatcgca agtttttcac
    17701 atggaatgcg tcaaaaaacg attttgatcg gcacgttgct gccagatcca gatatttggg
    17761 tattggatga acctttgcaa ggacttgatc ctcaagcagc atttgatttg aaagaaatga
    17821 tgaaggctca tgccgcaaaa ggaaaaacag tcattttttc tacacatgta ttggataccg
    17881 cacaacagtt atgcgataaa ctggctattt tgaagaaagg tgaattgatt tatcaggggg
    17941 cagttagtga attattgaat ggctcacctg atgaaacgct agaaaagatt tatttgaaaa
    18001 tggctggaag gcaagcgaca ggagatggac cgtatgtata agcgacaatt attagaatta
    18061 attcgagtta atcttttata tgttaatcca cagctcacga ataaagcaag agagaaagga
    18121 aaaaagggaa agcgattaac tatctatctt ttgtctcaaa atcttttttc agggctgatt
    18181 tttttactga tttacggatt tgctatgttt gctatgaact ttgttaaatt gccaggtttc
    18241 tttacttatt acgtggcact ttttggtatg ttaggtttaa ctcaaagtat atcagtcatt
    18301 tataatatct tttttgaagg aaatgacctg caagtatttt tgcctctgcc ttttggacaa
    18361 gaacaggttt tttcagcaaa gattttggta gttgctttga ccatcattcc ttttgttttt
    18421 ccgcttctag tcatgtttat tttaaccgga tggcgagctg atctagggat tttgcttact
    18481 atcattatct caatcctttt gttttctcta tttttgatta ttcttttttg tctggctagt
    18541 ttgattgttt ttggtttggc tcgaacagca gtgtttaaaa aacatagaaa aacagtttct
    18601 agtatcttgc ttggcagctc gatgctgatc gcatttgctg gaatcatgtg gatgaatcat
    18661 caaacgggga ctattgaaaa tgagttaaca gatcggcatc cgatttcgat attattgcca
    18721 ttctatgatg ctgccagtca gccactttct caacaaggtt tattgggttg gggaatacta
    18781 gctatcacgg ctctgggatt tttccttgct gtaaaacagc tgatagtacc aaagcttaca
    18841 gagcaactga ctgattcaaa cagtgagttc aaaataaaaa gaacccataa aaagaaccaa
    18901 aatgtgcatc agcttttatt tagttacaat gctcaattag taaaagaacc taatttgatt
    18961 atgcaagttc tttcttcttc cttgttaact ccaatcattt ttattcttgc ttttgcccta
    19021 ggaggcgaaa taaaattaac tgatttagat aataagttaa tcggtgttgt tttcctggta
    19081 gggatcgcat tggctttctt aacagttaat cagacttctt ttatcagcaa tcttatttct
    19141 ttggatcaag aaaattttct gtttatccgt tctttgccaa tctctatgaa ccaatattta
    19201 aaagaaaagt tcagattcgg atggatattg cagagttttt taactggtgg gatcgcatta
    19261 ttaagcggac tgtcttttca gctgcctttg ttttttatcc ctagcttgct atttggttct
    19321 ttattcggct gctacttatt gtcactacgt tatttcgcta gagattatcg gttgctgctg
    19381 ctgaactgga ccaatattaa ccaattattt aacagaggtt caggaagttt gggtttagtc
    19441 gcaactatga tgggttcatt gatcatcagt attattctta tcgtcttata cggaatgttg
    19501 gctttgtttt atccattttg gttagtgaat attcctgtga tcggtttagt tctaatactt
    19561 tccgctctat ggatcgttta ttatcaacga acgttttgga aaaaatttga ataaagaaga
    19621 ggggccgtga caaaaatcat gtcgcagccc cttttttaca gatagagggt gttcaaaagt
    19681 cagtttctca gtattaagtc aattttatgt aaaaatgtga gaagctattt ttacaaaact
    19741 ttttttaata ctcataatta cttcttattg ctcctgcggt tacttgtcgc aatgtttgtg
    19801 agatattttg tcatcgctca aggctgaacg tctctttcac aaccttttct ttgttacact
    19861 tcgtttattt aaaaagccgt ttttttcgtt tcatcatgat tgcgtcacgc tttactttga
    19921 aattacggat gttatggtta aagacttctg ataatacaag acctaaagcg attgctccag
    19981 caatcataat tgcttggacc gcataatgag ccgcttctcg ataggattca gtaacgagat
    20041 ttcgaaccgc ttgataagct aaaccaccag ggactagagg aaccatcccg ggaatattga
    20101 aaatcgttac gggcattttc aaacgtttag agaaaagatc gctgatgaat gctactccta
    20161 aagaaccaag caatgaacca aaagcagcag atccgcctat ttgaacacag atccagtaga
    20221 tcatccagcc aaaagcacca gaaagaccac aacaaatcaa tgaacgccta ggtacatttg
    20281 taataacggc aaatgccgca gtcgctaaaa aactaaaaga aaactgaata aatatcgtcc
    20341 ccatacttgt gttcctttcc taataaaaaa gctggaaaat aaaagcaatc gcaaaaccga
    20401 tcatcgtagc agtcatcatc gcttctgttc cgcgagaaac tcctgagaca taatgtccag
    20461 ctagcaaatc acggatagcg ttcgtaattt gaactccagg aactaaaggc atcacacatc
    20521 cgataatgat tagatcctga ttgcttccta agccaaaacg tacgctgtag atagcggcta
    20581 tgccaatcaa taaagaagat aaaaattccg ataaaaattt gattctaaaa aatttcaaac
    20641 tatatagata agctgcgtat cccaatcctc caatgactaa agtcacaggt aaatcggtca
    20701 tctttccgcc aaataacacc ataattgttc cactgatcac tgccgcgcta acgatttgca
    20761 accagacagg aaagaaagaa cggtctcggt cgattgcttg cagttcgcag taaagttctt
    20821 ctaatgttag ctctgaagca acatatttac gtgaaagatc atttactttt actacttttt
    20881 ctaaattaat cgaacggttg gtaatttgtt ccattcggat ggtcgaggta cgatcaagac
    20941 caataaagag accggtttga gtgacatagc tgaccaaacg gaaatttcca gaagctaaag
    21001 caattcgact catcgtatct tctacccgat acatctccgc attgctttcc atcatgattt
    21061 tcccagcgag taaacaagtg tccagcaaca gatctaattc ttttcccgtc atagcatctt
    21121 ctccaataat tgattgatta gttttatttt actacaaaac ataccagaag cgtaaagaat
    21181 aaaaaaactt gaggaaggaa taaaagaggc gtatactgtt tttgtattgc gggtgtagtt
    21241 tagtggtaaa atcccagctt cccaagctga tgtcgcgggt tcgattcccg tcacccgctt
    21301 aaaataggtt gtgaaaaagc tgctctgcaa caagtaataa gaacagccaa gcaaaaacaa
    21361 cttcttatgt ttttaacttg gatggactta ttaccgcaga tgcaagcttt tgcgcaccgt
    21421 ttaccaagcg gttgtgaaat cagtgtattg tcttgagtat gaagaaaatt tttgaataat
    21481 aataaatacc ttacagatag agtggtgact gattagagac gaggaatccg tctctttttt
    21541 gtatttttaa gccatcttaa aacaggtttt attttttgct gtttctattt ctttctagta
    21601 tttatttata ggggaacata tgttaagatt tagggagctg ttagtaaagg agtaaagaaa
    21661 tgagcaaaaa aacaaccaag gcgatcgtgg ggatcgtcgc tgctgtgatt gcaggggcat
    21721 tcggtgtttc caccacacaa aaagattcag atatctttca gcagattaca actatttttg
    21781 attccacacc acaagcttct caagtagcgg atgtgccaga atatgatgga aaacatcaag
    21841 aaatagaaat caatgggaat cagccggaat ttacaaaaga ggatcttagc ctttccaaag
    21901 gaacatggga aagctattca aatattgata aattgaacag agtaggacaa gccaatgcta
    21961 tgcttggaaa agatttgttc cctactgaaa agagagagcc tttgtatatt gacccgacag
    22021 gttggaaaca aaagaaatta agtgacgggc aatggttata taatcgcagc catttaattg
    22081 gtttccagct gactggtcaa aataacaaca ttaaaaactt gatgacaggg acacgttcgt
    22141 tgaatgctcc atacatgctt gctcacgaaa atgatattgc ggcatatatc aaagaaacaa
    22201 atcatcatgt acgctaccgt gtcactcctc attttgaggg gaatgaactg gtagccaggg
    22261 gagtgcaatt ggaagcagaa agcattgaag acaaaaaaat tgaattcaat gtctttatct
    22321 acaatgttca agatggctac acgatcaatt atgagacagg acaagcaaca aaaacaaaaa
    22381 attagtagca gctattcgaa ttttttatga atattatgaa aaaattgtgt aaaaacatac
    22441 attcaaagaa atatagcgta tactttatga aaagagtact tttgataaag ctacagaaaa
    22501 aaggaaaaaa acatacaaat agtgtttctt aatttattcg gaagtttgga atatttgttt
    22561 gtagttttcc ctttcttcga gtaaaataag gttgtagaag gtaagctgga attaccttgc
    22621 gggaaagagg tgtagaatca tgggttttac agatgaaacc gtacgttttg gttttgacga
    22681 tagtcgcaaa aaagaagtga gcgaaacatt agcgattgtt tatcgggctt tggaagaaaa
    22741 aggctacaat ccaatcaatc agattgtcgg ctacttgctt tctggagacc cgtcctacat
    22801 tcctcgttat cgtgatgctc gaaatttgat tcgccgtcac gaacgcgatg agatcatgga
    22861 agtaattgtc aaggactacc tctcaaatca tggagtgaat ttatgagagt aatgggcttg
    22921 gatgtcggtt ctaagacagt aggtgttgct atcagtgacc cctttggctg gacagctcaa
    22981 ggagtagaga tcattcggat caatgaagca gaagaagagt ttggctttga tcggttgaag
    23041 gaattagtag cacaatatga agtagaccgg tttgtagttg gattacctaa aaatatgaac
    23101 aattccatcg gaccaagggc agaagcttcc atgtcatacg gagaaaagat caaagaacta
    23161 ttctccttgc cagttgatta tcaagatgaa cgattaacca ctgttcaggc agaacgtatg
    23221 ctagtagagc aggcaaatac ttcaagagcc aaacgaaaaa aagtcatcga taaattagca
    23281 gctgtgatga tcttacaaaa ttatttagac ggctcaggta agcaattatt ttaataataa
    23341 aagaaaagag gtaatcttat gacagaacat aaccattccc acgaccatga aggacacgaa
    23401 cacatcacat tggtggatga ccaaggaaat gaaacattat atgaaatcct actaacagtt
    23461 gacggacaag aagaatttgg acgtaactat gttcttttat atcctgctgg tgtttcagaa
    23521 gatgaagatg tagaattaca agcttatgca tacatcgaaa acgaagatgg aacagaaggc
    23581 gagttagaac aaatcgaaac agacgcagaa tgggacatga ttgaagaagt attcaataca
    23641 ttcatggcgg aagaagaaga atagactata aagctaggag aaaccttgat atgatagggt
    23701 ttctcctttt tttatttttt actgtatgcc atattgtatg ccatctagtc aatatttaag
    23761 tgttgtacta atttttcaac agtcttttct ttcgtttctt ttgccaagtg accgtaacaa
    23821 tcgatcgtct gactaatttt tgtatgccgt aatctagttt gaacttctac catagtagct
    23881 ccagcgtcca agagcattga agcatgagtg tgtcttgcta catgcacacc gagaaatgga
    23941 accatagctt tttcacaaat agtaatcaat cttgcataaa tagcgtggtg tgtgattagt
    24001 tctttataga taccacaaaa aatcatagtc ggatcagtta caccaagtgt cagcatatat
    24061 ttccgctgat taatctgcca tttttttaat atagaaattg ttctttcatc tagtggaaga
    24121 accccagcac tacaatcagt tttaggatca ctgattttat agccattttt ggattggctt
    24181 agtgttttat tgatggtgac cgtattttct tgaaaatcaa tgtctgacca attcaatgca
    24241 agggcttcac tgatcctaac cccgctataa aagagaaagc gtagtaacgt tttatcaaag
    24301 tcgtttcgat aagtttcagg tttgctgttt aggtaatcaa acaaggtgat cagttgttct
    24361 ttactgtaaa ctttgacctt ttctttatgc ttagtggtgg ttcttttagg cattaatacg
    24421 ttgtctagtg gattagtctc aataatccca agattgatag cgtagctaaa aatacgctta
    24481 gaagttgaat gaagtacctt gtattggtca gtagtttcag cccagctatt tacaatttgt
    24541 tgggcttttt ttaccgtgac ttcattcaca cgaagatttc catattttgg aagaatccac
    24601 tttctaaact tgatttcagt tttcatgaag gtggcttctc ggacagtggt tttatatgtt
    24661 tctagccaca agtcataaac ttctttaaac gtttcgttgt tcgctttttt aataccgttt
    24721 ttatcgtagt ccacttgcaa gcgtgacaag gcaagctggg cttctttttt tgttttgtaa
    24781 cctcgtctac gaaccttatc aggtttgcca gtcattttgt tcattccaag ataggcttca
    24841 tagagccaaa atttaccttt tttagtttca tattgcttga atgttgccat aatagttttc
    24901 cctccatagt gtagcaagcc gtgggggcgg ttggaggagg cagtttatta ttattttgaa
    24961 tagtgtttat ttagctcagt aacaagagct gtgaactctt ttagaagatc attttcataa
    25021 aattcttgat actctttttt ctcatctgta tttttttctg aatcattaat taatgagtca
    25081 tatcgtaaaa gcgtatttag aagagctgcg agataagcaa ttggggtact cccgtcagga
    25141 aattcaattc gagatcctgt tttaagatat tttattgcgt ttgttaaata aatcttctgt
    25201 gagacagtca ggttatcttc ttcgatgtta ttgatagcat tagaaagatt agaatcaatt
    25261 atagagttat ttttttcaat agtttttttc aattgctttt caagcacatt tcgcttaatt
    25321 tcgggcatca tatgcatatc tcttaatgta taagatccgt ttaatagata ggtagtggat
    25381 acatctaata cctttgaaag ttgtttaagc ctggtgttat tgggaagatt atagccattt
    25441 tcccaattac taacggcacc tttactggcc ggtggggata atttacctcc aagttgttcc
    25501 attgagagtc ccttttcaat tctagccagt ctaattcttt gtcctgtctc cactgcttcg
    25561 gggtattttt ttctagccac attttcacca ccattcatat attttctcta ctatatcacg
    25621 atttaaatat gtgtgaaaca taaaagttca aaaaagtatg ttaaaattct tgcaaatgaa
    25681 aaggtatgat ggtatattga gtttataaga ggtatagaaa tgtattcaag agcctcttgc
    25741 atttttttaa aatctttgta tagaaatgta tgctaacgag gggggataaa tatggaatta
    25801 aaaattgaca aactcacgct tgatgatcca gcttttaaaa ttattgacga tcgagttgtt
    25861 caacaagtag agcaaactca aggaacgtta ctttcattat tagaaaaaaa gtaccagttt
    25921 ccaaaatata tgaacaaggc acaagctgct aagtatatga acgtttcata caatactatg
    25981 atgcagaaat atgttcctaa cggtttaaag ttgattatag ttgatggagt cgtaagaatt
    26041 tcacaagatg aatgtgatcg ctttatggaa gaataccaaa aataaacgca agccgtgggg
    26101 gcaaagggat taataggagg aaataataat ggaatcgaca caaaataaag caatcgaaaa
    26161 agtattatca acaattctta cagaagacac agcggcagaa ttagcaaact tggaaggcaa
    26221 agcgctagaa gaaacgtttg aatgtttgta cgaacaaatg gactatcaaa aattgctacc
    26281 acaagaacca acggtaagcg gagtattgcg tggcttgaac gatttagtac aagcagagtt
    26341 taaagaacga ctttctattg aagagtatca agaaattttg tatcagcaag ttgagttgtt
    26401 agcgagcttg ctagggcttg aactggagga cgttgaatga aaactgaaat ttggaacgga
    26461 cacattataa gatttgtcga tattaatgat gaatggtggg cagtggcgaa agatgttgcg
    26521 gaagcgttag gtcttaaaca ggttactaga gccattcact ctttgcctaa agatggggtt
    26581 actactagta aggtcatcga ttcattgggc agaacacaag atgtaaacat catcaacgaa
    26641 aaaaaatatt taccgcatgg cattcaaaag ccgtaaaaaa gaagccgagg catttcaaga
    26701 ctggattttc gacatcatca aagaactacg ccagtccaca ggacttgaag gctttcaagt
    26761 attccgcatg ctagacaaag aacaccaaaa agaagcaatg actaaattaa gccacgctat
    26821 tactgaacca aaaccagtag actacattaa agcgaatgtg atagccaata aagctgtatc
    26881 aactatttat ggtcattcca aaatggtaaa aaagaaagat atgactcctg aaatgttggt
    26941 tgatcgtgaa cctattttag atgagacagt agaattaatg actgttaaag aaaaatatgg
    27001 gttgcagttt tcagtgagtg agaaaattta taatcgttct gctgaattgc agacaactta
    27061 ggagcattaa catgatcgag aacaaagaaa aagccttatc cataacagtc ttggcggaca
    27121 ggataaaggc aacttaattg ggataaaacc cgatattctt tgttccgatt ataccatatt
    27181 aaaaaatcgg agggaaccat tatgaaacga aacttaatta taggaagcat tttaatcggc
    27241 ggaattttcg gcttattacc attaattgca aaaatagcta tctttgcagg attagcgtta
    27301 tatctcttca ctgcttatga cgagtacgac tatcaattaa gaactggagg gcataagtag
    27361 atgtacaaaa caaaactatt aaaccaactc gatagccttg aattagagga aattaatcaa
    27421 gggatcgctg aactagaaaa taatatcggg aaaacctact ttggaaattc attcaatgaa
    27481 aaactaacag ttttgtatgt actcaaaaaa catgcagaac acaaaataat ttgtcgagaa
    27541 atcaacgagc taaaaaatca gattttaacc gcatggttaa acattactga tatgcaagaa
    27601 gcaagggtga aaacatttaa tacatgggta aagtatcaga atcaattaaa aggtgctgaa
    27661 tttgttcggg atgggttgaa atacgaactt gagcagttga agctcatgga ggtgtctgaa
    27721 tgatttatac cagtattttg aaaaaggagg agaggtttat tggcaaataa ttatcaagca
    27781 gcaacggaat tacaaaagtc gggatggtca atttatccct tatctcctgg aactaaaatt
    27841 ccaataaaag gctctagtgg ttggaatgat gcaactaacg attctaatca aattaatgaa
    27901 tggtggacgg aagatgcaac tagaaatatt gggttaatgc ttgaagatca tcaaatggtg
    27961 gtagttgacc tagatcaaca ttctgaaaca cgaaacggcg ttgagaatta taaaaaactt
    28021 gcttcaatgt atgatccatt tccttctact tatacggaaa tcacaccagg taaaggaatc
    28081 catttcttct ttaaaattcc tgatggtgta attatccaac aagaaacagg tgcatttgct
    28141 gatatcttcg ggcgtgatga taaaggtaaa agtttaagcg ggattgatat tatcactaaa
    28201 ggagttccaa tagcgccaac tatgattatt tcaagaagtg ttgggagagc atatgaacct
    28261 attgaaaacg tatctctaaa taatattgca ccagctcccg attggctagt gaacctactg
    28321 ctaaaaaaac cgcaagaaat aaagactcaa taccgacccg tagcaaaaac agggacagca
    28381 aaaaaattag atatgattgt tcaaggcgct ggcgaaggta gtagaaacga tcatttaact
    28441 aagttatgcg gttggttact atggcacggt gtagataatc aaactttagc agaattgatt
    28501 tatacagcaa atgcgtacaa tgaaccaccg ctaaaagata aagaagtgaa tcaaattatt
    28561 cgatcgatga ttaaaaaaga tttgaggggg aaagctcatg gctcataagc ataaattaga
    28621 tagtatttta gactttcccg aagccagcga gcgtgaagac aatatcattg aattgaaaac
    28681 ctggatgtca cgattaagat gcaataaaga cgatcagatt aaaagtaaca gtgttgtgaa
    28741 tgcagaattg attttaacca atgatagcaa tttagctgga acaattgctt ataacgaatt
    28801 tagcggatac attcacctat taaaagattc tccttggatc aatcgtaccg ctggagaatg
    28861 ggaagacagt tttgaggatg ccttaacggc atatattgaa gaaaactaca atgtagtttt
    28921 tgatgacaac aaaatacaca aagcagtagt aaatgtggct agaaagaatg ttttcaaccc
    28981 agtaaaagaa cgtatcgaaa aagttaaatg ggatcaacag cctagactgg aaacactgtt
    29041 tattgacctt ttaggggtag acgacaacct ttacacacga gaagtaacaa aacgttggat
    29101 agtcggatca gtcgcacgta tctataaacc aggaataaag tttgagatcg ttccagtttt
    29161 ggatggaccg caagggattg gtaagagtac cgttccagca ttactttaca cggatgattt
    29221 tttcaccgat tcattagatt cgctaggtga aaagaaagat gattatatgc agcttcaagg
    29281 caatgtaatt attgaacttg gagaattatc ttcaatgaac aaaactaaaa ttgaacagat
    29341 aaaaaacttc atcagtgcca agatcgataa aattagacct ccttatggtc ggaatgtcat
    29401 agcttgggca aggcaatgtg tatttattgg aacgtcgaat gatgggcagt atttgaaaga
    29461 tgatacagga aaccgccgtt tttatccttt gccttgtaag aataagccaa agatgaatcc
    29521 gtttaaaaca aaggatgaat attttcttca agtgttagct gaagcaaagg tgctttttga
    29581 taaaggacaa cgaatctatt ttagtcccga tgaagataaa gaagtcttag aaattgcaaa
    29641 agactatcaa gaggatgcca agatggagaa tccaattaaa gaagcaatca ctaaatattt
    29701 ggaaatggaa atcccgtata aatgggaaga agctccagcg tgggcgagac gttcttatta
    29761 tcagaactat cctgacagta aatgtaatga gaaaaattta cagcatttct ataatggagc
    29821 tactatgcaa caagagtttt atttagttga tagcgtactc accgctgata ttttggaagc
    29881 tgtttttgat aaacaagcaa aggatttatt gaatggtcga tcagatgcag aaactaaaaa
    29941 gattgccttg attattagca gtattcctgg ttgggaacgg aagcaactgc caaaaagaaa
    30001 taaacgacga ggattttaca ataagtcaaa tgcctatgaa aataaaaatc gagctggaaa
    30061 gtacaaaaag taacgggtag taacgggtca gtaacaccta gcccgttact agtttaccct
    30121 tactgcccca agggatacag caatttggta acggggtaac accttatttc cttaaaactt
    30181 ttgaaatagt tagctaatat gctggggaat aatgttactg gattttaccc gttacctgtt
    30241 accaaaacgc tagaaccctt gtccccgttg ggattgagtg gtaacgggta cctgttacgt
    30301 aggtgttacc acgtgttacg aatcaaggag gaaagtaaat gctcaatatt atttcaacaa
    30361 acaaagcacc gaactttcaa tatacagatg aaatggatcg gtttctaatg aacacgctgg
    30421 catttagtgt gggattggta acagaagatt attccacatt tgatccagaa gtattaaaga
    30481 taatggaaga agaacctgat tggctgcagg agtcagtagc gtggtgtcaa tcgctagtag
    30541 tgggatcatt ggtagatagt ggcaactatg atgatacagg tgagctaatg gatgaattta
    30601 attgtctgct taacctatat gatcgagcga gacaacgaga gcttacatcg aatgaggata
    30661 atttgttttt aaacatccat gataagttct tggctttgct actaacagat gatgaattga
    30721 taactaattt attggaggta gaataattat gcatatggaa agtattagat acttcgatgg
    30781 tgagaaacac attgagtatt caaacactca agaagatgta gactttatta gttttgagga
    30841 agataaaatc actaaagtta attttaaaga cggaacgtgc ttgaagatag tttcgcctta
    30901 tattgaatac aaatcaaaat gggaacaaga tgattctgac gaacgagatc gctttggttg
    30961 gtaatctatg gcagttaaaa aacaatgtaa tcatgctgga tgtaaaacat tgattgatta
    31021 taggcagaag tattgtggga agcataaagc aaagcaaacg gcaattaagc gtgaagaaag
    31081 aaagcaaagc gaaggtaaat attttcaatt ctatcaaagt agaacatggc gaaaggcttc
    31141 atacttgtat cggttaaatc atccagtatg tgaggattgc ctagaagaag gcttgataag
    31201 gaaagctgat gttgtagatc acaaaattga actaaaagat gattggaata gacggttaga
    31261 tgaaactaat tttcgttctt tatgccatgc acaccataat tccaagacag ccaatgaaag
    31321 acaaagacga gaaaagagta ccctttgagt taagggggca tagtgtgaaa cttactgaca
    31381 atcgatgcct actcattttg gtacaaataa ccgttgtgaa aaggcataag ggtaattaca
    31441 aataacgatt acacttgtaa tcacaagtga aaaagtatat aatgaaagta ggagatttat
    31501 tgaaaaatac aattgttatt actgataaaa cagggaaaca gcgcaccatt gagttacctc
    31561 attttggtca agtgaccatt caaatgcaga acggaaaaat catttatata gataaattag
    31621 ataaagaaaa attctgatcg aaaaacgaag gaatgtgagc ttaattgctt acgttccttt
    31681 ttcttttgtc tgaaaggagg acaacatggg acaccctaaa atattacacg atacaaaagg
    31741 caatatatca agtgaagaaa aagcaatccg tgtggacgct agagaagaat tgttcaagca
    31801 gcaaccatta ataaatatca cgccccctga ctggatggca gcgagcgcta gaagtgaatg
    31861 gaatcgtatc gtaccaacat taaaaaaaga ttatccattg agtgaagcag attatggttc
    31921 attggtagcc tattgtttag cctttgctcg aatgaaaaca gccgaagccg agataagaaa
    31981 atcaggtacg tttatcacat gcgaaaacgg agtaaagaaa gccaatccag cggttcgggt
    32041 tcaatcacaa gctatgagtg atttgaaaaa acaagccacc tcactaggta tgaccttaga
    32101 atcacgatca aaactagctt tgaacaaggt taaaaatgat gaacccgaag acccgttcaa
    32161 agagttgatg aattcatgaa tgattacatt gagaaagtcc tatcaggtaa gctgattgca
    32221 cccaagaaaa ttatccaagc gtgtgagcgt catataagcg atttggagcg ttctaagtca
    32281 gatagcttcc cttatgtgtt cgatgaagaa caagccacca aagcgattaa attcattgag
    32341 ttgctaccat ctacggacgg taaagcaatc aagatgttag gatttcaaaa attcattcta
    32401 ggcagtcttt atggctggcg tactaaagaa gggaattaca ggcgattcaa tcgagcgttt
    32461 accagtatga gccgtaagaa tgggaaaacg tatatcgcaa gtggcatggc tgccaatgcg
    32521 ttgattatgg aacaagaacc agcagaagca aggcaagtat tgtttgtaag taacgctttg
    32581 aaacaagcta aattgggcta tgatatgctg tctaattcac ttagaaacgt ggtcaagtct
    32641 agtaagtttt taagaccaca actgaaaatt atgaactcta agattcagca cttgccctct
    32701 aattcgttcg ctatggcact ggctagtgaa accagcacgc tagatgggtt tgcaccaaca
    32761 accgcaattc ttgacgagtg gcacgaagca aaaactcgta aaacgtacaa cgtcattaag
    32821 tcaggaatga cccaacaaaa gaacggctta ttgtgtgtta ttagtaccgc tgggcttgat
    32881 ttaaacgttc ctatgtacga ggaatactta ttgttagatc gtgtgctaaa aggcgaagaa
    32941 caagccgaca ggtactttat agcgatatgg gaattggacg atcccgaaga aattcacgat
    33001 caagagaaat ggatcaaagc caatccgatt tttgaaagtg aagaaatcaa aaaagtaatg
    33061 attccaacca ttcaagatga tgtgaacctt gctttgaaac aaaataacct taattctgta
    33121 ttggtgaaaa acttcaattt atggagacaa gcgagtgagg acagctatat gattgctgaa
    33181 gactggcagg caaccgaagt agaaccacaa gatattacag gcaagcccgt ttatatcgga
    33241 gtggatttat ctaaaacaga tgatttaact agcgtttcat ggatcgtacc gctagataac
    33301 ggcgaacttt attgtgattc acatagcttt gtagccacca aatatgggct tcaagacaaa
    33361 gaaaagcgcg acggtttgcc ttatcgagaa ctagaaaaag ctggtgagtg ttccattact
    33421 caattagaaa gtggaatcgt ggactatgac caagtatttc agtttattca agatttgatt
    33481 caagaaaatg atttggaatg tatggggatt tgttatgacc cgtataacgc taattcgctt
    33541 atcagtaaag ctgaaaaagc caactaccca atgttagaag taagacaagg aacgattact
    33601 ctaaacgttc cgacccgaac ttttagagaa caagtttatg aaggcaacgt tattcacaat
    33661 aaaaatacga ttctcaccca tgcagtgaac aacgctattt taaaaacgga taacaacggc
    33721 attcagatta ataaatcaaa gaacagtaac aaaattgatc caatagctgc attaatcaat
    33781 gcctatgtgt ttgcaatgga ttacttcacc acaacggaag gagcgaaagc agacaatgaa
    33841 ttttatacaa gtgaagaatt ttctttctaa ttacattcat accgttcttt tacttcttgg
    33901 attggtgtgt gtgttggttg ctatcacctt actaacaaat gtctactatg gcttgttagc
    33961 gctgggcata gtgcttattg gggtagcggt catgctaaat acagaacaga agggaggtta
    34021 aaagatggca ttttttaaag cgagacaaaa tacaacggga gatcctttcc tacaacatgt
    34081 ggtatcaatc caatcggatg attacaccac cagctttaca agcgttcgtg cattaagaaa
    34141 tagtgatgtg tttgcagccg ttcgaattat tgctagtgat attgcttcaa gtccgattca
    34201 attggtcaaa aacaatatgc cacaagctga taatgaactg gtgaagttac taaacgagaa
    34261 acctaattca gaaatggatg gttggcattt aaagtttgct ttggcggtca atatgttgct
    34321 aaacggtaat agctttgcag agattaaacg caacggtgaa aaggtagaag aaattcactt
    34381 attacctaac tcaagtgtaa cggttactca attagataat ggtacgttgt cttatcagat
    34441 tggtgataaa aaaagacgtg tgaagtctag cgatattttg cacttcaaat atttcaccca
    34501 agatggttta acaggattac caccacttta tgcgttacgt gatgaactga aaattcaaca
    34561 agctggcaac cgcacattgc acaatttctt tactcgtggt gtcagtgggt caggtatttt
    34621 gaaggttcat aagtcagatt tagacggatc agcaaagaac gcaattcgtg aaaagtttga
    34681 agaagccaac ggttcaagta gtggagataa tgctcttaga acgatcattc ttgatgaaac
    34741 aatggactac aaaacattag aaataaacac cgatgttttg aagcttatca attccaatga
    34801 ttggaacaca aaacaaattg ccaaggcgtt tggtgtaccg attgagcgtt taggcgttga
    34861 aaatgaacat tctagcaccg ttcaaagtaa tctccagtat atccaaagta cgctgattca
    34921 ttactttaat gtgtttgtga gtgaattaga tacgaaactt gaaaccaata tccgctttaa
    34981 ttccgatcag ttactagaga ctgatcctga aacaaaagta aaaaatgtat tggatcaggt
    35041 caaagggtca cttctcacga ttaatgaggg gcggtcgaaa atggggctac cccccatgga
    35101 tggtggcgat cgtttactag caagtttgaa ctttacgtat ttagatacgt tggagaaata
    35161 tcaattaaaa gaacaggaag gagttacacc agttgaataa tgaagaagaa aaggaaaaac
    35221 ggctgacaga agaagctgag ctaacagccg attctcccaa agtagagaaa gaaaatgaaa
    35281 aacaaccaac agacggcaaa actatttcag gctatgcgtt gaaattcggg caaccgtcaa
    35341 aagatttagg cggctttgta gaagtgatta cacccgaagc attaaaagag gtggatttat
    35401 caaatgtgtt cttattatat ggacacgatt attcaaagcc actagctagt gtcaaagcag
    35461 gtacgttgaa attgaatgtc gatgatacag gattacattt tgaagcagag ctaaccgaca
    35521 cgacctattc aaatgatgtg tatgagaata tctcaaaagg ggttgttgat tctatgtcct
    35581 ttgggttcgt gcttggatta gattcattcg acaaaaaaga agatggcaca attgaacgat
    35641 caatagataa aatcaaagca cttaatgaaa ttagtgtcgt gaccgttccc gcttatgatt
    35701 catcaaatgt ccaagtaaat aagcgttctt acgaatcgtt tatgagtaac aaccaagcaa
    35761 aacaaacaaa caatagctta gaatccactt ctaaagcaca aaaggagagt aataacatgg
    35821 aaaaaacttt aatcgataac gaaaaaacag aattgcgtgg gtatgaagaa tatatccgtt
    35881 cacaaggcga agtgcgtgat ggagtcacta ctgtaaatgc agcggcagtt gttcccgaag
    35941 aagtaatcgg tgaagtcttt gatttgaaac gttcaaatta taacttagct caatatgcaa
    36001 cagtaaaaac agtatcaaat ggacaaggta aatatccagt agcaactaac caacaagcag
    36061 tgttagcaac aaaagctgaa cttgctgaaa ttggtgatat tgacgctgaa atgtttactt
    36121 cagttgatta taaagtagaa actcgtgctg gtaagattgc cttatcaaat gaggttgtgg
    36181 aagattcagc agtgaatatt gtacaagagg tcaaagatca gttagcgaaa ttggtagaaa
    36241 acactgacaa taagcatatc atggatttat taaaaacatt cactaagaaa acggctgcta
    36301 cgttggacga tttgaaacaa ctatacaatg tggcattaga cccagcatta aataaaatgg
    36361 taattctaaa ccaaagcgga tattaccacc tagatacatt gaaagattca gatggacgtt
    36421 acattttaca acccgatgtg acagcaccta gtggtaaatc attattcggt atgccagtag
    36481 tattgattgc agatacattg tttgccaatc ctaaagctgg aacattccct atgattatgg
    36541 gggatattgc acaatctatc tttgttgctc gtagaaatca agtaacgact caatgggaaa
    36601 aattcgatta ctactcacaa ggacttgcag tgatcgttcg caacgattat aagaaaattg
    36661 atcaaaatgc ttcagtgtat attgagttta cgccagttgt aacaccaaaa gtatagaaaa
    36721 atattgggcg gcggtttatc ccactgcctt tttttcatta ggagagataa aatggtaatt
    36781 ttggatagca taaaaaaaag tatgcggatc gatcacacta ttgatgatga ctttattcaa
    36841 caattgattg atacagcagg cgaatatata aaaagtgcta ttgatagtag cgcaacggat
    36901 aaagatatgg ataattatca gcaatttgat ttggcggtgt cattacttac tcaacattgg
    36961 tatttgaacc gtcaagaagc cagcagcgaa cggataccag taacggtaca agcattagta
    37021 caacaaatga gaggtgctta ttatgccaat cattaagaat gtaaatgaat tgactgagag
    37081 agtcaagttt aaaaagacaa aacgggtaaa agatgaagat gggcagatgg tggatagtga
    37141 agaaactgta tttgaatgtt gggctaatgt gcgttcacaa atgctaaaag acgtgcttgc
    37201 tagtgtaggt accattcttg aaggaacgtt gacgtttatt attcgatacg atcaagatta
    37261 tgaactaaca aacgatatga aagtagcttg gaaaaacaag agttataaaa ttatttcaat
    37321 caatgaagga acggcgttta aagattatac aacgatcata gctaaacaga tttcttagaa
    37381 tgattacact tgtaaacgtt gtgggtattt agtataatta aggtagtaaa tgaagggtta
    37441 gctgcctgaa ttttgcaaga cttagctagt cgaaatctat tgttggactg aaaattgtag
    37501 gtgtggttgc aaacatgctg gactaagaaa gatgatagat gatgaacgtt caattttaat
    37561 acaggcatgc taggactgat tggatggttt tggcaagctg attgtgtaga aatcaaagaa
    37621 cacgtctgtt gtggacgtgt tttttttgtt ataattcaaa agaggtgatt taatggacaa
    37681 agcagagttt acaaattttt attggaagta ttatctacat ttagaaaatg agtttattaa
    37741 taccacagat tttgtgatgc tcgatgagaa taatttcaaa acattctcta ttgaatatca
    37801 aaaactacta ctagcgattg gttcggagtg tgagattatt ttcaaagaac tttgcggatt
    37861 tgatagcagt agcaataaaa gcataactga ttttaaagct gttattaaat ctagcgaatt
    37921 aatgtgtttg gataatggtg ttagggttat gaattcttta acattgactt cactaaaacc
    37981 ttttggagat gggtggcctg aagatacacc agattggtgg aaaatatata acagagtaaa
    38041 acatggtcgt tcttcaaatt ataaggaagc aaatttggaa aatgtgttgt atgctttagc
    38101 aagtctatat ttattagagg aatatttgca taagaaagta atactagaag gtgaagtaga
    38161 ctttataagt ccagagtcaa atctatttac gttatcttgg gaaagaaaac attcgtcgat
    38221 gcaaaaagtg acgtttgaaa aagtggattc aaattatgta gctccactca ttgattttaa
    38281 agaacaagaa gaaatttaaa aacccccacg gcttattgaa gtttttgtat gccatattgt
    38341 atgccatttg gtttaaatcg cttgaaaaat agtgatagat aactctaatt catttagtca
    38401 taaacgctgt tttgataacc tttatagttc tttgatatgg gtttctcatt catggcggaa
    38461 gaagaagaat agaacaaaag aatgaattaa taagatataa aaaaagggat tgtgacaaac
    38521 gtcttgtcac aatccctttt tccaaataaa cgatgttcaa tcagctgccc ctcggcattc
    38581 gctcgaaaaa cggcgaaata tgaagaacta ttttgccatt tgtttctcta ataatcaggt
    38641 caaaacgttg acttcacagt ctcttcctta aacggtgttc tcctgccaac tcctcggtca
    38701 caagtcacaa tattcaacaa acatgagaag ctgttttttg aaattgttcc ttgtgactcg
    38761 gagctgaacg gcaggctcac gacctctttc ttaaacggtg ttcaaaagct tgcatctgcg
    38821 gtaataagtt caaccaaacg aaaattatga ggagctattt ttgtttggct gttcttatta
    38881 cttgatgcag gacagctttt tcacaacctc ttttcgttta gcactaaatt tccttaaaaa
    38941 gtagaaaagc tttcgaagcc tcgtttgttt cttttactgt ataataaaag aaaagagtaa
    39001 caatcgctaa aagatataaa caagagaaag gaaatacaag atgattggtc tgatttattt
    39061 tgtggtgatc gttctggcga acacagttgg cgctatttcc gggatgggtg gaggcgtgtt
    39121 gatcaaaccg attcttgatc ttatcggcgc ccattctgtt gcagggattt ctttttactc
    39181 aacagttgcg gtattcacga tgtccattgt ttcgactgtg cgacaagtat caagcgggaa
    39241 atcactgaat tggcagattg tcggttgggt atctagtgga gctgttgttg gaggagtagt
    39301 cggcaacatt gtattcgaag tttttttaca gttatttgaa aacgagaagc atgtgcagct
    39361 gatccaaatt tttttgacgg tattgacctt ggtttttgcg ttcttctaca ccaagcatca
    39421 tcagccaaaa tttcatttga cgtcatggac ttggtacctt atatgtgggg gggttctggg
    39481 ctttttagct agttttttag gtattggtgg tggaccagtc aatgtttctt tgttgatgct
    39541 gatgtttgca ttgccaataa aagaagcaac actatattct ctatctacga ttttcttttc
    39601 tcaactggca aaattggtaa cgattgcttt aacaagtagc tttatgcgct ttgatttatc
    39661 tatgttgttt tatgttatcc ccgctgctgt tattggaggt ttgtggggag caagatttag
    39721 cagggttttg tctccaaaaa aagtgacctt tatttttcaa gtaattgtcc tcgtggttct
    39781 tttggtcaat tgttacaatg cctttgtcat cttacaaaca ttaggagaat ctagactaac
    39841 gcaagtcaaa atcactgaaa catattgttc taaatgaaaa aaggagtata ctgtgataaa
    39901 aaaattcatt taaaaaaata aaaattggct ggtgatttgg atgttgcggg aaatgcgttt
    39961 aggagatgca gaagcactac gagaaatcaa tgcggaacaa ttaggatatg atgtaccatt
    40021 aaccgttacg gtgagacaaa tgaagaaact gttgaaggag ccagaaaaaa attttttctt
    40081 ggtctatgaa gatcctactt ctaaaaaagc agctggctat gtacaagcgg agtcctatga
    40141 atcgattttc agcgatccga tgttcaatat tatggcactt gctgtgtcta aacatgctga
    40201 aaaaagagga atcggaaagg ccttgatgac tggcgtagaa gaagcgaaaa gacgaggaat
    40261 atcagcaata agacttaatt ctgcagaata cagagtagaa gcacaccgat tttatgaacg
    40321 catcggttat cattccgata aaatgcaaaa aagatttttg aaaatcctgt aaatttttat
    40381 caaaaaatac ctggtcatca agccgatact tgatgatcag gtattttttt tgactaagaa
    40441 agtaattgca tcaagaaacc tgagatgatc aaaacgatgg caccaccaag ccgattgccc
    40501 atttgagcaa aagcaataag ttccatccga ttagctgcag ataagacagc tacatttcct
    40561 gtaccaccca tcgagttgtt gcataagcca gcagtaatag ttgattcgat tggatataaa
    40621 ccaaacaaac gaccgacaaa tcctgaaact actgaaatcg cgataacact tgtcaaacat
    40681 aagacaacaa attgccatgt caaagcagaa gccaatacat ttagattcaa taacgcaata
    40741 ccgataccgg caagaacagc tgctgtcaag tttttgacaa tcaagttgtt gaacatgata
    40801 gctgcatctt cgtaatattc tggtaatagg tttgcgattt tacagataac aacgataatg
    40861 atcatgaatg cgtaagcatg gactttagga acaaaatagt tacagatttg tcctaagatg
    40921 aagaaagtca atgataccat caaaccgaca cctaattgtg gaatggaagg ttttacattt
    40981 ctaggttttc catcgccaag gtcgcctttt tccattaatt taccattacc gttgaatttt
    41041 ggcattgatt gtcccgcacg agcaactaac gctgcaccaa tgatagctag gacatttgtc
    41101 attgctgtcg caggaatcag gcgggaaatg atagaagaag cgtccgtacc taaaacattt
    41161 gcataaatcg ttgataaagg tacagctccg gctccaacac caccagccat tgcgggcaat
    41221 gagatatata aaacggaatt tgcaaaacca tttccgataa gcatacctac gagtcctacg
    41281 gcaaaaaagg agacgaccat tgaaataagt gcaacgggaa taaaacgaac agaagctttc
    41341 atcaatagat tacggttcat accaaggatg ctaccagtaa tcaaggcagc aatataaaag
    41401 tctaaaaagc ccatattgct gacaaagttt tctgtggatt ttactacata ctcaggtaag
    41461 atcccaaatg tagcaatcgc ggcagaggca aagatcgcaa aaacggagcc accacctaaa
    41521 taacttttga cgatagggat ttttgttccg ataaaatgaa ataaattacc gaaaatgacc
    41581 aaaacagcga ttgggccaat catattcgtc ggtaattttc ctaaagccat tgcaatgatc
    41641 aggacaagga ccatgatcaa ataaaggggc aaacttacgc cggtaatttt tgttgaccaa
    41701 aacccttctt ttttcttttc ctcaactgca gttgcggttg ttgttttttg tgccattttt
    41761 acagatcctt tcttattctg tatcgtatga aaaaagccaa agagaagcgg caaaagagca
    41821 gtagttggct ggctgctgtt ttgccgcagt cgcttttttc tttttagacg tcatacaaag
    41881 tttctgtatg ttcttttact ataacaatct taatcttcta aagatttata ttcaggaacc
    41941 catttagcag attcaacagc ttctttgata tccgtgattt cttcacgatt caatttttgt
    42001 gcaacaactg attttgcgac agtttcagca atcgtttgag agaattcagt gatttttgct
    42061 actggaggca agatagctgc tcctggtttt gttacatcaa cgattccgcc taatgctcga
    42121 ctagcttgag aaatgatttc agcatttact cgtgtagctg ttgaagcaat caaaccaagc
    42181 cctaaacctg ggtacatcaa cgcattattt gcttgaccga tttggtaagt tacaccgtta
    42241 tattccacat cagcagcagg gatacctgtt ccaactaaag cttttccgtc cgtccattca
    42301 atcaaatctt ttgcttttgc ttctgccaat tttgttggat tagacaaagg catgatgatt
    42361 ggacgtgggg tatgagccgc catttctttc acgatttctt cagtgaatgc tccaggttgg
    42421 gtagaagtac cgatcatgat cgttggatgg attgctttta caactgcttc taagtttgtc
    42481 aattcatcag cattagtgaa ttctgagcgt ttacgagcga atgggatttg accaggagtc
    42541 aatccttttg tatcttcaaa caataaaccc tgtttatcta cttgatagaa atgttggcgt
    42601 gcttcttctt caggtacacc ttgacggatc atttcatcta aaaggatgtt tgcgatacct
    42661 acaccagcag taccagcacc aaatgtcaag atcgtttgat ctttcaattg ctcacctgat
    42721 atattcaatc cacctaatac accagctagt acaacgattc ctgtgccttg gatatcatca
    42781 ttgaaagtag tgattttatc ttcgtatttt tctaagatcg ttgcagcatt tcctcgtcca
    42841 aaatcttccc aatgtaataa caattctggg aataattcag tagctgattg aacgaattga
    42901 tcaatgaatt cgtagtaagt ttcgccttct acacgagcat gacgattccc taagtataat
    42961 ggattattca ataattcttc gttattagta ccagcgtcga ttgatacagg caagacttgt
    43021 gcaggattga taccagccgc agcagtgtag accatcaatt taccgatagc gatgtcaaca
    43081 ccgttcacac cccagtcacc catacctaag attccttctg catctgtcac aacgatcaaa
    43141 cgaatgtcgc gtccatctgc tgcgtttttc aaacttgctt tgatattttc tggttcgtcg
    43201 attgaaagaa atgcagcatc ttgtggtttc aagaaaattt cgttgtattg ttcgattgaa
    43261 tccgcaacga caggatcata aacgacaggc atgaattcaa ctaaatgttc gcccatcaat
    43321 ttataaaaca atgtccggtt cgtattgaat agattcatta agaagatacg tttttccaaa
    43381 tcggtctgtt tgcttaagta ttgaccgtaa gcttggacag attgttgttc caatgtttgg
    43441 acagtacttg gaagcatacc agtgattccg tattttgccc gttcttcttt tgtaaaagct
    43501 gttcctttat ttagaaaagg attatttaat aagtttagcc ctgtaagcat gaatgattcc
    43561 tcctaagttt taatacaaac gaagtatagg agtcagatga ggatatagtc aaaaagagca
    43621 ggtataataa attttattta tatgagtaat agagtcaaaa gaaatcaaaa tagcggtatt
    43681 tgttcttttt atatcaacaa tccttgcttg attactatgc gtatctctta tatgctaaag
    43741 aaagaaaagt agaagaataa aggatatgtt agatagataa atagaatctc tgaagaataa
    43801 atcacgtgat cgtgacgata aaatacactt acgtcaggtg ataaaaaata cataagtaga
    43861 aaactaagag gaggaacaga aaatgaaaga agttcaattg atcagaaaaa gcgaactatc
    43921 agaaggtggt tgcaatgcat gcggcgtagt agaagcaaca agctatacat taaagcttgg
    43981 tgccaacaaa gcgataatct ctgagttgac agtaggcggt cttgtggaca gtctggcgct
    44041 tgctgaaggt tttattggag aagatattta tgagatgttt tcagaaatcc gtcagttaaa
    44101 aaaaggggaa aactgcatag aggttcatca tgagagcccg aatgtgagat tcaaacgtgg
    44161 tgataatgag atgatcttca ataatcatgt gtccgatcac accgagctat atggaatcgt
    44221 gaatcaaata ctaactgagc tttttggatt gggaccttat gcgttcaagg aagaaaacgg
    44281 taatccaaaa ttaaacgaag aatggcaaga aacgattgaa atacaaagaa acaacccgca
    44341 cttatttcaa taggcatcca cagtatttcg taaaagggac tttgacacga cttttgtcaa
    44401 agtcccatcg ttttttatct atttgtgttc taaacatttc tttcagagta gtaacaactg
    44461 gaatgactga aatgtaaaca gattatttgc ctgtatcaat acggaagagt aatataaagt
    44521 gtgtaaacgc tatcatatta ttcattcaat tttttataga gggaaggcat tgaaatggaa
    44581 aaaacgtatc aagcaggtac aaatgaagga atagtggatt ttatcaatat ggaagattta
    44641 gaaatagccg cttcacaagt gattccagct ggtggttatg gttacatcag cagtggtgct
    44701 ggcgacttat ttacttatca agaaaatgaa cgggcattca atcatcagct gattattcct
    44761 catgtattaa aagatgtaga attacccgat acaactacac attttgacaa agaaacgctg
    44821 actgcaccaa tcatcatggc accagttgct gctcatggct tagctcatgt gaaggcggag
    44881 aaagcttctg caaaaggtgt agcagatttt gggacgatct atacagcaag ttcttacgct
    44941 tcttgtacat tagaagagat aagagaagca ggcggggaga aagcaccgca atggtttcaa
    45001 ttttatatga gcaaagatga tgggatcaat ttggatattc ttgaagtggc caagcgtaat
    45061 ggagcaaaag caatcgtatt gacagcggat gcaacagttg gcggaaaccg tgaaacagac
    45121 cgcagaaatg ggtttacctt cccactgcca atgccgatcg ttcaggctta tcaatcagga
    45181 gtaggccaaa cgatggatgc tgtgtacaaa tcttccaaac agaagcttag tccaaaagat
    45241 gtagaattta ttgctgctca ttctgatttg ccagtctatg tgaaaggtgt ccagtcagaa
    45301 gaagatgtct atcgttcatt agaatctggt gctggcggaa tctgggtatc taatcatggt
    45361 ggccgtcaac tagatggtgg tccagcagcg tttgattcgt tgcaatatgt ggcagaagca
    45421 gtagataaac gtgtaccaat cgtgtttgac agcggtgtac gacgcggaca gcatgttttc
    45481 aaagcaatcg catcaggtgc agatcttgtt gctattggca gacccgttat ttatggattg
    45541 tctttaggag gaagtacagg agtccatcaa gtgtttgatt tctttaaaac agaattggaa
    45601 atggtcatgc aattagctgg aacacaaaca gtagaagata tcaaaaaaat aaaattgcgt
    45661 gagaatcgtt ttatttaaga aacaaatgac gaaaaaaata ggagtgcggc agatgatgcc
    45721 gtactcctat ttttatagtt caaggatgtc actaatagaa taatttgaaa cgaaaaaata
    45781 aaattgaaat attttttcat acttaataaa aaaggaagaa tattcatgta aacgatttta
    45841 ttgttttttt ctcttttata caaaaagggt cataatttca agtaagcgga tgaattcatg
    45901 aggatttttt gcatactgtc tctactatac ttaggtcact aagaaaaagg agtgatttat
    45961 tatgaaaaag aacatgattg ggacattatt actttcaaca cttcttctag gcggcttggc
    46021 aacaccagct tttgctgagg gtcaagcgac ttcaaaagga gatattacct ttactgaacc
    46081 aacaaatacc gtggagcctc ttaaccctac tgatccttca aaaccagtag agccagcaga
    46141 tccggaaaat ccagcaactg gccagacagg tcctttaaca ctggatgtag ttcccgaatt
    46201 gccatttggt acacacgaga ttgaaagcgg aacaaaaacg tatcaagtag acgcttcaaa
    46261 aaacgataca ccttatctcc aagtatcaga tcgtcgaggt gtaggtgcag atggccaagc
    46321 acaagggtgg aacgtgacag tttcggtttc agattttgta aacggttcac aagttttgca
    46381 aggcgctgaa ttagattttg gaacatccac tgttaaaagt acgtcagata acgaatccac
    46441 tggaccaact agtcaaactg taactgggtt gagtaaagca agtgcagcga caccaatatt
    46501 tacagcagca aaagatcaag gtctgggaac atggctttct gtttatgatc cagcaaatat
    46561 cacactgaaa gtgccgaaag cagcagctgg aacattcacg gctgatttga cttggaacct
    46621 cgtggctggc ccagtagcat agagtatgaa ataaattcaa caaactgcgg tgaaaatact
    46681 ataggtgaag gattttttac cgcagttttt gttgaaagga tgtggtggac aatgaatcaa
    46741 agtaaacgac tgtttgtttc gtttttttct attttaagtc tatttttcat ttttccgtca
    46801 atcagccaag caaaggattc agcaggagac tttggaatca aaccggtatt tccagagaac
    46861 caaatagata aagcaatcgg ttattttgat ttattagtgg caccggaaca aaatcagaca
    46921 ctagaagtaa ttatcagcaa ttcttcagat gaagaacgaa catttgaggt ctctgtcaat
    46981 ccggcggtaa cgagtgatgg tggaacgatc gattatagtc aaaaaaaccc aacgttagat
    47041 gagacattgc cgtttgatgt ccgtgacgtt ttgctcattg cgaaaaagga aatcaatgta
    47101 tcagcacatg cagaaacaac tgtacctata gaagtgaaaa tcccagcaaa aagctttaag
    47161 ggacgtgtat tagcgggtat tcatgtttca cctaaagaag aagctgaaac agaaaatgct
    47221 acagaaggag cacaaatcaa aaatcgtatt gcttataatc tcgcagtcgt tttacaagaa
    47281 agtcaagaga cgatagaacc ggatctgaaa cttttatcag gagatttgga cgaggtcaac
    47341 gcaaagccaa ctgttcagct tcgtttccaa aatcctcagc ctaggattat cagcaatttg
    47401 atatttacga gcaagatctt ttatgaaaat cagctttata ttgaaaatac gtctaatgca
    47461 tttttagttg caccaaattc gaattttcac ttgaatcttg atttagctgg tgataaagca
    47521 aaagccggcg attaccgcgc agaaatcata gcaaaatcag gcgacagtaa tgaatggcga
    47581 tttacacaaa actttacgat caaaaaagaa aaagcacaaa aagtaaatga aaattccgtt
    47641 tttgcagtac aagaacaatc tttcccatgg ctttatgcag gattggttgc tgcagttcta
    47701 gtgttatggt tgattttgct gtttttgtgg gtccacaaga aaaagaaaaa aggagaaaca
    47761 acatgatgag gtgatttcgt tgaaaacatc gatcttattg ggagggatta ttgcaagttt
    47821 gctgttcttc agctggcaag agccagtcca agcagatacc aaaagttcag gtacgattac
    47881 attttatgat ctaagtccaa ttccgcatcc aagtggttca gtcaatggcg catcaaaaca
    47941 gcagacacag ctaccgattt ataaagaatc taatcaacat ggcgtattcc cggagacgaa
    48001 tgaacaaaag atccgttttc tttatttgat cattggtata gaattatggc ttcttgcgtg
    48061 gttgttgtta tggagaagaa aggaaaagga ggatgaacat gttgctacaa aataaatttt
    48121 cattttttcg ctccttcttt tttacttcgc tttttgtttt aagtatattt atcttttcac
    48181 cttcggcaga agctgttgga gcaacgcctc ctgccatttc ttatgatcca tacacgtatg
    48241 aaaatatcgt acctccaaat ggtggacgta gtgcagtcaa tggcgggaag cttgtccaac
    48301 taactggggc taaccaattg cctaaattga ctgctactta tttgaacgat ggttcaaatg
    48361 atccttggaa aggtggcacg gtccgttttc attgggaaag ccatgtgaaa ctaacaaatg
    48421 tacttgattt ggtgaatatc actgcacaag gatttgcatt tgtggcgatc atcaatttgc
    48481 cggaacatgt atcaagcagt gatgtattaa aagcaattga ctggaacaac gcctacttgt
    48541 atattgccgg tgcccccatc aaggttacta gcggaagttt attatcagca ggaagccata
    48601 ccttgcgttt tgggatgggg tcgtgggata caaatactct attgacagat attattgcta
    48661 ttattacgcg aggcgaattc aacgtggacg atatcccgct tcaatttgat gttacagcta
    48721 atgtcgcgaa gatgacagaa aacggagata aatatgatac gagtccaaac aaaattttga
    48781 ccaagggtaa attacaacct tctatgtcta aaaaggccgt tttttctgtt gatttttatg
    48841 attcgaataa tattatccaa gatcgtatgt tcaattcgat tttagctcca gctgcaggta
    48901 gattttatcc taaattaact ggcggaaact tgaatccagg agcatatgca ttttctgcaa
    48961 gtgcagagat aaatacgtgg aatagttaca tctcaccaag tgattcaaca ggaaaatata
    49021 atacatttgc tgataccaca gaatacgtgg atggaaataa ccagaacctt ccaggctcta
    49081 ccaatagtcg gacattgacg atggggctga ctgaaggacg ttttgatcag ttgccattta
    49141 gtcgctttga tcgcgtagtc aactatttta caggaaaaaa cgttacacaa ggagcaatac
    49201 tgactcatac tccagcaagc acaagtggat tgaatcagac agccaatatc gtgtacagtg
    49261 ggaaagatgc gcaaggcgga ttgctttctc ctgttgcttt aaaggtattg gagcagtaca
    49321 agctagacgg aacggtttta ccaacaaact taacagccga tagtcagtgg ggaaagctcc
    49381 tttcttctgc atcgtaccaa gtcacggcca attggtcagc aactgaacta aaaaagggtt
    49441 cgatccatta caggctttat tcgaaaggaa cccaaaaatt agcgacagga tggacagatc
    49501 aacttttcca aacgatccaa tcaaataacg ggggtgtaaa tacagctact tctacactac
    49561 ctgcattggc ttcagggcaa tattattttg attatcgctt ggtggacgat gtacttacta
    49621 acatgtatcc gtcttttgcg tacaaatggc agtctgaaca agctggaatc accactcttc
    49681 ctcaaataac agtggctaat tttccatctg tgagtgcaga tagtcagcta aaaaacctta
    49741 gcagacaacc tgagacagga gatcccctgt ctgctctatc aggagatacg attcaagaaa
    49801 atgtgacatt cacgttaaca aaatctgggg atgcgataac cgacaaaaaa atcacgatct
    49861 cacttcctga aaatactact tatatcaatg gttccttaaa attaaatggt acaactatcg
    49921 cagataccgg cattcaacaa ggagtttctg tcccagcaga tctattgagc aaaataggag
    49981 ataccattca tcttacttac aactatcaat taaatactgt agatacttct ttacaatccg
    50041 tcagcatact gacaaaggca gctgtacttt ccagcaatat tacattagca gatggtgcta
    50101 agcttcctaa cccagttgtc caaacatctg ctaaaacaat tcttgtcccc aaacaagaat
    50161 taacattagt taatgtacca gatgatttta catttggtaa cgatctcccc aaaccgttga
    50221 agacaagtta ttatgaatca aaaggcgatt tttcttttga tgtgcgggat actcggcttc
    50281 caagcacgtc tccttggcaa ctgacaggta cattgacttc tttatttaag aatgatcaag
    50341 gtcaagaatt aagcggaaca aaattatact tcaatcattc tggatcaaag caattgattc
    50401 agcaaggtca aaacacgttg atttatgaga gtgatggaac agctaaagga gaggttctcg
    50461 ttgactttcc cgataccgat ggtttactct tagaggtaaa tagcagtacg aatgctcaac
    50521 ctggcgcaac gtatcaaggc atggtcacat ggaaactgac agctgggcca accagctaag
    50581 tgattagaat ttgtatggat ctgtgataac tgtcacagat cctctttttc aaggatgaga
    50641 aggaaacttc tgctgttaaa atcagaaatg cttgaaggag tggacttgga acttttcagt
    50701 ttgcttgaaa aaaatgaaca acggcaaatc aaacttttcc aacttttatt agaggaaaaa
    50761 ggagaggttt ccgttaataa cgtacttacc cgcttatcag ttgatcgggc taccttgaaa
    50821 gaagatctgt tttatttaca agctaacttg gaaaatatca aacaattgga aattgttatc
    50881 caagaaggga atattttatt aatcagacat ggaaatatag cagcagtcga tgtttattat
    50941 cattgttact tgcgctattc tacaaaatat cagatacttc tttatctgtt ggaaaatggc
    51001 tcatttgatc ggcagaaact tgtcatggaa cttaatatca gttcggctac tttgtctcgc
    51061 agagtgaagg aattaaatga ttctttaaat gagtttcatc tgaaaataaa aagcgggcgg
    51121 ctgaccggtc cagaaagtca aattcgttat ttttatttcc aattattttg gtttggacgt
    51181 ccctatcttg aaaacaaaaa agaatacagt gatttatcag gaaacacttt tttagatctg
    51241 ctgcaaaaag agtttagttt tgctattaca gaagaaggac gattgaaatt tgaaatatgg
    51301 ctttccatta tgaagaagcg aatgcgctgt acgaaaaaat ccaaaccaga ttatagcaat
    51361 cttcctgttg gattgtttca aacgacacaa tttttattgg acctccatac atttttgacc
    51421 cgttacttct ttcaatatgc ctttccttgg aatcaaaatg aaacgttggt tttttatctt
    51481 ttcatgatca gtaactttac attagataca cataactcgc atgtccagga gtttttgata
    51541 agcgaaaaat acaaagacga cgtagtagct caattgaatc gaacgtttaa acaatcgata
    51601 gaagaatatt tctcttttta tgtttttcca gaagagattt cgcaaaagat tgcgttgaca
    51661 gtgatgcaaa atcacgctca ttttgcctat tttagaggat ggatgaatat ttttggccaa
    51721 gaaggattaa aacagcggtt aactgaagta gaagataaac aattcctggt tttatgtgaa
    51781 agattggtca gacaaacatt tgctattgtt gattttactg aagtagacga ggaaaatgcc
    51841 cgctttgaat tatttgctcg ctatgcatct attttacgga cgctgatcaa gcagttagaa
    51901 ttacgtctgc aaattgctta tgatcttcct tatgaaaggc taatggcgga tatcgtgaaa
    51961 gaaatcatcc aggaacaatt gctgaatacg atcaaatatg atttagtcga atacgagaaa
    52021 gaaaagcagt atgatatcat tttgactagc caattgaaag agtacccgtc acagaagtcc
    52081 gctaaagttt ttgtattcac tagcaacgaa tataattatg atttccccta tttgaaccaa
    52141 tttttaaaag aatgttattt agaaaaattg aatttaagga tgaataaaac atgaaaatcg
    52201 tgatcattgg tgcttcccat gcaggcatca cagctgccct aaatctaaga aaacttcaac
    52261 cgaaagcaga agttttactg atcgatgaag atcataaaga tggactaggc tatgtttcaa
    52321 atggaatcaa cctttattta aaaggaaaga tacgtagttt agctgaagtt gcccataaca
    52381 tgcggactct tcaagaaagt ggggcaaaac tgatcaccga atggagagta actgaacttg
    52441 atccagacaa acatcagctc atcctcgcat ccaaagaagg aaaaaacgag accataacct
    52501 atgataaatt aatcgtagcg acaggttcct ctcctgtcac cttgtataaa caaattgaag
    52561 ctgaaaatgt ctacacctat aaaaatctag tgcaatctaa gcaagtactt gccgctttaa
    52621 aagaagcaaa agaagtagtg atcttcggtg ctggttacat tggattggaa ttagcagatg
    52681 ctttgagaaa taaaggatac attattcatc tagttgatta tatgccgaat gttttatcaa
    52741 gatatttcga taaggatatg atcaacagtt ttcaaaatca gctgcaaact aagcaaataa
    52801 atttttatcc aaatgaattc ttgatcgatt ggaaaaaatc agaagagaaa gtagtatccg
    52861 tacaacttct gtctcaaaca ataaaggcag atatggtcat tttttctgcc caaactcgtc
    52921 ctaatacgac attgttaaaa gaaaaagtgg ctttgtatga ggatgagact gtgatagtca
    52981 atgaatatct gcagacaagt gatccggaca tctatgcgat tggagatatc gtcccagtca
    53041 gttttgacaa aaataaacgg catctctttt tacctttagt tactcgagct gtacatatgg
    53101 caagagcagt agcgctaact ttgagtggtc agccaaccgc ttacgacctc agacaaaaga
    53161 taacagcagc agtcattata gactactttt taggaactgt agggctgaca gaagatgaag
    53221 cgccattctt ggaacaaaat accggttcgt gttcaggaga atttgatcta tttccacaat
    53281 acgacgaaga aaacaaaaca gtaaatgcaa agctgatcta ccatccggat acattagaaa
    53341 taattggcgg acagctgata agccaagaat tcttattatc agatttgaac ctgcttgcgg
    53401 atatcgtgaa acacaaaact acgattccac agctagcagt tgaggatttt ggatttctgt
    53461 ctgaatacac ctctcgtttt cactacctca atgagttagc ttttaaagta ctagctaaga
    53521 gagcaaatag caatagagta gataaaagac tgtgagaaat atcacggtct tttattgtgt
    53581 ggggatataa taaatattaa tcaatcgaga ataaaaaatt catataatga aatagcggaa
    53641 gaattttttg agcataatat tcgccaaaaa tttatcaagt gataaaattg ttgtataaaa
    53701 tgattatttc aggaggagga gttaaatgtt tttagcatta aatgaaatta tgcattcaaa
    53761 gttacgttat gcgttagttg caggggtgat gtttttgatc gcctacctgg tatttttttt
    53821 gactgggtta gcttatggct tagctcaaga taatcgaaca gcagtcgaca agtgggaggc
    53881 agattcgatt gtgctttcga aagatgcaaa ttcaaatcta gggatgtcca tgattactaa
    53941 gaagatagca gaagaagtcg aaggtgggaa agtggcgtat cttgcccaaa cacctggagt
    54001 cgtgactagt aaagacagta cagaagaagg aaaaatcaat gttagcttct tcggtatcga
    54061 taaaaatcaa ttcatcatgc ccaatcttgt tgaaggaaaa gcttttgata acgatgatga
    54121 ggcagtaggc gatattagtt tgaaagaaga atatggtcta gccataggag atacagttaa
    54181 gttatctggt agtgacaaga cgtttaaact aactggcttt acggatcatg ccaaattcaa
    54241 tgtctcacca gttctctata caaccatcaa tgcttaccaa gaaatccgct tcgaaaaaga
    54301 agatacaagt gaaaatgcac ggattaacgc aatagttgtc agaggtaaaa tcagtaattt
    54361 acctgaagat ttagaacaga tcaaaatttc taaattcatc aatgaattac ctggatataa
    54421 tgcgcaagta ttgacttttg gatttatgat cggatttttg atcgttattg cggctattgt
    54481 gatcgggatt ttcatttatg tactgacgat gcaaaagatt aatatctttg gtgtaatgaa
    54541 agcacaaggg atcacaggag gatttattgc gcgttctgta gtggcacaaa cattcatttt
    54601 atcatttgtt ggtattcttc ttggtctatt aggaacagtg ggaacatccc ttgttctacc
    54661 tgatgcggtt ccattccaaa gcaattggct gttttttggc gtcattagct tgttgatgtt
    54721 agtagtagct gtgttaggcg cactattttc tgttcggaca atcgtaaaaa tcgatccgtt
    54781 gaaggcaatt ggataagaag gaggaagaac atgaaagcaa tagaatttaa agaagtagaa
    54841 aaaagtttcc aagatggcga ccaagtagtt aaagcattga aagaaacaac catgagtatc
    54901 gataaagggg aatttgttgc aatcatcggt ccttctggtt caggtaaaag tacttttttg
    54961 actttggcag gcggattgca gacgcctagc agtggctctg tatttatcaa tgatcaagaa
    55021 ttcagtaatc aaaaagaaag cgaacgcgtt aaactacgtt ttaaagaaat tggctttatt
    55081 ttgcaagctt ccaatctggt tccttttctg acagtaaaaa agcagttatt attagtagat
    55141 aagattaaac atgaacatcg tcaaaaagaa gcaaacgaat tatttgagca gcttggcgtg
    55201 gataagttga tcaacaagta tccagaagaa ctatctggtg gagaacggca aagggtcgca
    55261 atcgctcgtg cattgtacaa tgatccgtcc attattctag cagatgaacc aactgctagt
    55321 ttggattcag aaaaggcacg agaagtagtc gatatcttgg caaaagaatc aaaagacaaa
    55381 aataaagcaa cgatcatggt tactcacgat acacggctga ttgacaaatg cgatagaata
    55441 tttatgatgg aagatggtgt attgaaagaa aaagaataac caaaaagcag gtggaaaaat
    55501 ggtccatcga tacaacaaag atacacagca aaaaattttg aaagaagcga ctgacttgtt
    55561 tatgtccaag ggatatctcg gcacttcaac aagagaaatc gcacaaaaag ttgggatcac
    55621 ccagcccaat ctctatcatt atttcggtga taaagaaaaa ctatatacgg cagttttaga
    55681 aaaccactta aaagatgttg gaaaagcttt gagagaaatc gttcaaacaa gcgaaacggg
    55741 atttcaagta accttgacaa aaatggcgca gtttttgatt gagacacatc tggtcgattt
    55801 gtttctgatg cttcacgatc ttgaaagcaa tctttcaaag gaaacaagag atcatctttt
    55861 ctttctatgg aagaaaaatt atcgtgaacc ttttgaagaa atcttttcag caaaccaatc
    55921 tgtgctaaga aatgggattt caaaagaaat cgcagcaagg cattttttct tagtgttagc
    55981 accttacatc actcggtcga aaagacctgt ggaagaaccg ctaaatgtgg cgcaattgat
    56041 cgatttatat ttgaatggtg tattaggaga agcgtaaagc tgttatatag ggagaaaata
    56101 gttaggtgaa gaagcaagat atgacgaaga tcgttatatc ttgcttcttt atataggtag
    56161 tttttcataa agacaaattt gttattctct catgattatc agggtatatt tttatttatt
    56221 atgtcggtgt tccaggaagt gttttaattt aataacgaag aaattaattg tttgtagaat
    56281 gaaggaaact atttattggg tagatgaatc accacgaata gtcaaaagga gatttcagga
    56341 tatgccaaaa atgaaaaaaa tcattttagc agtaatgtta ttttctacgg ttatatcttt
    56401 tacagcccct tttttgctta cttaagctga ttttaagttt tggcccttag tctggatcta
    56461 cgaggtgaga gtcaagaatg aaaaaaataa ttggagcttt tgtatttgca atcattatca
    56521 ttattatctg ttttcaaata gatgtttttg gtcaaaaaaa gatagttgga caaacggtca
    56581 gcagtacgaa cagtacggtt acaaagacaa aggaatcatt tgatgataca gaacaagaga
    56641 cattaatcaa aatcggaaaa aatgaccgta cactatatac agatgactcg ctaactaccc
    56701 cacttgcaac tataaacggc ggagagctgg cggagtttct ttctgaaaca aaaaatgctt
    56761 atcagatcaa gacaaatgat ggctatactg gatatttagc cctcgaagat ggaaccaaag
    56821 tcacaaagaa tatacaaaca aaaccggaag agctatctga tgcagtgatt gtattagatc
    56881 ctgggcatgg cggaaatgat actggggcat taagcaatga tgaacaaaca gaagaaaaag
    56941 atataacatt aagtacagcc ataaaagtaa aaaaggcgct agaggatgct ggagcaacgg
    57001 tttatttgac ccatactaca gatgaattag tacagcttgg agatatatgc gactacagtg
    57061 aagaaaaaaa ggcagatgtc tttatcagtt tacacgcaga ctctacggaa tatgcgaatg
    57121 aagcaactgg aatcacgaca tattattact atggacaaga ggaaacatta gcacagacaa
    57181 ttgctgactc cttcactgat ctgcctctgg attcaagagg aatctccact gggaactatc
    57241 aagttcttcg agaaaatctt caaccttcta ttttaatcga gatgggttat atgaataatg
    57301 atagtgattt aaaggaatta gtaacagaca gttatcagca gcagattgct gcaagtttga
    57361 cacaagcatt gaccacttat tttcagtaat aaataagccc agccaaacaa aaatagctcc
    57421 tcatattttt cgtttggccg ggcttattat cgcagatgca agcttttgaa caccgtttat
    57481 ttttttagta gcttcaaagc tttttctgta tttgcaaagt gaagtttggc atatttttca
    57541 agcataggca tgccgccttt ctccaatagt tttgccgcta cttggtcaga tttcgttcca
    57601 gctcctgatg gaagggtgat tccagcttca gctgatgctt tgtgtaactc ttccaaaaag
    57661 ctggcacgac tgatgataga agcagcagca acagctaaat gatattgttc tcctttagta
    57721 acgaagtaca gtttttcttg taattgattt ttttctaaac gcgcatattt tttaaaattt
    57781 gcttccggcg taaactgatc gatcaaaatc gcttctggtt tttctggctc gatttttttt
    57841 agcagcaaat ggatcgcttg attgtgcaaa gcgactttca tccgaacggc attgtatttt
    57901 ggttggatct cattgtattt ttctggagat aagacaagca gtttataggg gatggttttt
    57961 tttaagatgt cagcaagctg gatgatttgg ctatctttta actcttttga atctctaaca
    58021 ccaagtttac gtaattctgc aagctgatca cgtttcacat aagcagcaca tactgttagc
    58081 ggaccgaaat agctgccatt tccgacctca tcactaccta aaacggataa ttgactgata
    58141 ttttttggca aagaagaggc tgtttttgct ggcttggctt gtttatcctg tgcctccccc
    58201 catttatcag cttctattgc tgcattcgta ccttgaaaca tcacttttcc ggatgtataa
    58261 gcggtaatgg tcgtcccgtc tttttttgca gcaaagctag tataaggaat ctgtttattt
    58321 aacaaataag agcgatagta tgctttcatt tgactaagtt ggtcgtttgt tgctttgata
    58381 atgacgttgc tcataaaatt ctcctcgttt ttatacataa aactataccg caactcacga
    58441 cttttcgttt tctaagagat tgcgagacat agcatttttt taaagtttat catataatag
    58501 ttaagtatgt gaaaaatatt tgtggagaac ggtgaaagaa ccaacttcat ggtacactaa
    58561 ataaaacttt catcaaatag gaggaaatga ttcgtatggc gcacgaaaaa acacgctaca
    58621 aagcggtgat tgccaaccaa acatatacta ttatcggacg ggaaaccaag catcatatgg
    58681 atatcgtaac gaagctgatc aatgaacagt tagcagaatt gaaacaatta tcaccacaaa
    58741 tggataatga acaagcagca atcttgatgg ctgtcaatgc gctttcggat caattgaaga
    58801 aacaagaaag aatcttggag ctggaagaag aaacagcaga attaaagaaa aaaatgatca
    58861 aatttacaga gcttgaaaat cgtgtgaaac gcattgaagc aatcgagaac gaagctcggg
    58921 aagtattgaa agaaaatggt caagcagatc ataccattaa aaatcatgtg gaagcacaac
    58981 agattttaaa cgagaaacga aaaggacaaa ttaaacaaaa atcttctaat taagatcctt
    59041 ttatcaaaat aagaaaaatt taaaaaaagt tagaagagaa aggaacgtag catgctgagt
    59101 ttgctgattt tatttttatt gctaattgcg tttttttctg gagcacgtcg cgggtttgct
    59161 ttgcaaatca tattcgcgat tggatatgta ttgtcattta ttgctgccca gcatttttac
    59221 aaaccattag caagtcattt ggaattatac attccatacc cagctgtcac gccaacatca
    59281 aagttagcat tttttgatca ggtatttgcc tttcacctag atgaagcttt ttatgcagga
    59341 actgcttttc tgattatttt gctaattggc tggctgctta cccgatttgt gggggttttt
    59401 gtccatggat tgacgtatgt gccgatcttg agacaggtag actggattgc aggaggcatc
    59461 ctgtcactaa tcatggctta cgttactata tttttgattt tgcagttact tgcctttgtt
    59521 ccattagatg tggtccaaaa tcaattcggc gagcatagtt tcgctcgctt tatcgttgag
    59581 agaacgccat ttcttaccaa caagatgtat gagctttggg taacgaatat tttgaattaa
    59641 ggaaaatagt gctggaaaat atttcgtttt ttgtacagag tagattattt aagaaggctg
    59701 cgtagcgtat gtccggcaca gctctttttt catagtgaaa gataaggtga taaaatgaat
    59761 aaccgaatcc ttgaaacatt ggaatttgaa aaagtcaaac agatggtcag acaatttgta
    59821 gtgactgcac aaggaaaaga agaactggca gaattggtac cagtgagcga ggaacaaacg
    59881 atcacaaact ggcttcaaga aactgaggat ggattgaaag tgcaacgtct gcgaggcggg
    59941 atccctatac ctaaacttga aaatatccgt ccccatatga aacggattga gatcggagca
    60001 gacttgaatg gagtggagct tgcacaagtt tccagagtat tgtctacgac aagcgaattg
    60061 aatcgtttca ttgatgatct ttatgacagt gaaatcgaat ttgcacgttt gtatatgtgg
    60121 gcagatcagt tagtcacgat ccctgttttg agccgccgtt taaaggaagc aatcgatgaa
    60181 gacggacgcg tgactgatga cgcttctcct gagttaaaga gcataagaca gaacattcgg
    60241 cgaagtgaac aagctgttcg tgaacagtta gatgggatcg tccgtgggaa aaatgcaaag
    60301 tatttaagtg atgcgatcat caccatgcga aatgaccgct acgttatccc agtcaaacaa
    60361 gaataccgcg gtgtatttgg cggtgtagtc cacgatcaaa gtgcttcagg acagacttta
    60421 tttattgaac caaaacaagt ggtggatttg aataatcgtt tgcgtcaata ccaaatcgct
    60481 gaacgaaatg agattcaacg tattttaagt gaactttctg ctgaacttgt tccccatcgt
    60541 caagaaatca tccacaatgc ttatgtgatt ggtaaaatgg atctgatgaa tgcaaaagca
    60601 cgatttggta aagaagtaaa agctatcgtg ccgggaatca gtgaagacaa tcatgtcgtc
    60661 ttgaaacaag caagacatcc actgatcgat caggaaaaag tagtttctaa tgacatcaca
    60721 atcggaaaag actatcaagc catcgtcatt acaggaccta acacaggtgg gaaaacgatc
    60781 acgttgaaga ctttaggtct gttacaactg atggggcaag caggattacc gattcctgca
    60841 ggtgaagaaa gtcaaatcgg tatttttgag gaagtatttg cggatatagg agacgaacag
    60901 tcgattgagc aaagtctatc gaccttttct tctcatatga cgaacactgt agatatttta
    60961 tcaaaagtca atgaaaaaag tctggtatta tttgacgagc tcggtgcagg aacagatccg
    61021 caagaaggtg ctgctctagc aatcgcaatc ttagatgatc ttggtaaaaa gtctgcttat
    61081 gtgatggcaa caacgcatta tcctgaattg aaagtttatg gatataatcg ggcaaatacg
    61141 attaatgcca gcatggagtt tgatgtggat acattaagtc caacgtatcg tttgctgatt
    61201 ggcgttcctg gacgaagcaa tgcgtttgaa atctctagcc gattaggtct tgatacagaa
    61261 gttattgatg aagcgaagca gttgatgaat gatgagagcc aagatttaaa cgaaatgatc
    61321 acagatttag agaatcgccg gaaaatggca gagaccgaat atctggaaat gcgtcatttt
    61381 gtttctgagg cacaagaact tcacgatgat ttgaaagaag cttacagcta tttctttgaa
    61441 gaacgtgaaa aagaaatgga aaaagcaaag aaaaaagcaa atgaagtcgt gtcagaggcg
    61501 gaagaaaaag cagaaaaaat cattgctgat attcgtaaaa tgcaacagca gattgggcaa
    61561 ggaaatgtga aagagcatca gttgatcgat gcaaagaccc aattagcaaa tctacatcaa
    61621 gaagaaactt tgaagaaaaa taaagtattg aagaaggcga aagaacaaaa aacgttgaaa
    61681 ccgggagacg aagtgttggt tacgacttac ggccaaagag ggacgctttt acgtaaaaac
    61741 gggaatcagt ggcaagtaga aatcggtata ttaaaaatga atgtgtccga agacgagctg
    61801 acgcctgttg ctcctcaaaa agagccgaca caacgagtta tccatgctgt acgatctgaa
    61861 tctagtagtc acgtgccgaa tcaattggac cttcgaggaa aacgatacga agaagcgcta
    61921 agtgaggtag atcaatattt ggattctgcc attctagctg gttatcctca agtgactatt
    61981 gtccacggaa aaggaacagg cgcacttcgc aagggaatta ctgattatct taaaaaccat
    62041 cggagcgtca aaagctttga gtttgcaccg gcaaaccaag gcggaaatgg tgcgacaatt
    62101 gttaaattta agtaaagctt actaaaggta agcagatggt tcgctatcca agtatagaaa
    62161 tgctatacta gtcatagatt ttaaaaatgg aggtctttga tatgtcacaa gtaattacag
    62221 ataagacatt taatgaagaa acagataaag gacttgtatt gattgatttt tgggcaactt
    62281 ggtgtggtcc atgtcgtatg caagcaccga ttttggatca gttggaacaa gaatatgatg
    62341 aagaagaatt cagaattgct aaaatggatg tggatgaaaa tccagaaact cctcaacaat
    62401 tcggtatcat gagcattcca acattaatgt tgaaaaaaga tggtcaagta gtagaaaaag
    62461 ctgttggtgt tcattcaaaa gaacaactac gtcaaatgat cgatcaatat ttataaaaac
    62521 ttacagcaaa aataagctga gggtgggact gaatccagtt ccgtcctcgg tttttttgcg
    62581 gttgagttaa ggttattcaa attaatattt tttgagtata attacgttgt caggctggat
    62641 tgtttttttg acagacatgc tataataact ttaattgaat atgaagggga gtaccagatg
    62701 aacgaacgaa tcaaaaacaa attagcttta cttcctgatc agcccggctg ttacttgatg
    62761 aaagataaaa atggaacgat catttatgtc ggcaaagcca aaatattaaa aaatcgtgtc
    62821 cgctcatatt ttactggtag ccataatacg aaaacggaac ggcttgttag tgaaatcgaa
    62881 gactttgaat acatcgttac agaatcgaat atcgaagcat tgctcttaga gatcaatctg
    62941 ataaagaaaa atgatcctaa atacaacatt atgttaaagg atgataaaac ctatcctttc
    63001 cttaagataa cgaatgaaaa atatccccgt ttggtgatta ctcgtaaggt actaaaagac
    63061 aaagcactgt attttggacc atatcccgat gtcggtgcgg cgaatgagac aaagaagatc
    63121 ctcgatcgat tatttcctct gagaaaatgc aaacctagtc agacgaagga gccttgtctt
    63181 tactatcatt tgggacaatg tctgtgtcct tattatttcg acgtagatcc gaaagtctat
    63241 acgaaaatcg ttgatgaagt gaaaaacttt ttaaacggag gacacgaaaa aatcgagtca
    63301 gagatccatc agaaaatgga aaaagctgct gaaaacatgg agtttgaaaa agctgcagaa
    63361 taccgagacc agatccgtgc cattgagaca atcatgactc gccaaaaaat gacaaatact
    63421 gatttactgg atcgagatgt atttggttat gcgattgata aaggatggat gtgtgtccaa
    63481 gtgtttttcg taagacaagg aaagctaatt gaacgagatg tttcaatgtt tcctttctat
    63541 aacgaagcag aagaagattt cttgacttac ctcggtcagt tttatcagga aaatgagcat
    63601 ttcattccta aagaagtctt gattcctgat acgatcgaca agcccagtgt agaagctttg
    63661 ttagctacga aagtgctgca accaaaacga ggagaaaaga aaaaattagt tgaattggcg
    63721 agtaagaatg cctcagttgc tttgaatgaa cggtttgatc tgattgccag aaaacaggaa
    63781 cggacgatcg gagcagttga acgtttagga aacgcgatga atatcccgac cccaatacgt
    63841 atcgagtctt ttgataactc taatatcatg gggacgaatc ctgtggctgc gatggtcgta
    63901 ttcattgatg gaaaaccggc aagaaaagaa tatcggaaat ataaaataaa aacagtcaac
    63961 ggaccggatg attatgcatc aatgagagaa gtcatctatc gcagatattc gcgagtgatt
    64021 cgcgaagggt tgcctttacc tgatttgatc ttgatcgatg gaggaaaagg acaagtagat
    64081 gtggcaaaag atgtcttaga aaatcaatta ggaatcgata ttcctattgc tggcatggca
    64141 aaaaacgata aacataaaac aaatgagttg ctattcggta cagatttggc tgtagtaccg
    64201 cttgagcgaa attcaccaga gtttttctta ctccagcgaa tccaagatga agtccatcga
    64261 ttcgcaatca ctttccatcg gcagctacgc agtaaaaaca gttttgcttc ccgattagat
    64321 gaaattgaag ggttaggacc aaaacgaaaa aaaatgctgc ttaaagagtt caaatcgttg
    64381 aaaaatatca cagcagccac gacagaagaa ttacaagaaa tcggactgcc gaaaaatgtc
    64441 gcacaaaacg tatttgataa attacatcag gaatgaggaa agggcacttt acaaagaaag
    64501 taaagtgtcc tatcatttta tgtacaacaa aaagagcgtt tacgttttgt tggtaaataa
    64561 taaatcgctt acgtctggtg tctaaggata tatgtgattt cttgaagaag gagtgaagaa
    64621 atgttagaag tcaaggatct tgttaaaact tttgggaact acacagctgt cgatcatgtc
    64681 tctttccaaa tccccgatgg aaaaatcatg gggctaattg gccaaaacgg ggctgggaag
    64741 acaacgactt ttcgtttgat cttggatttt ttgacacaag accaaggaga agtgttatgg
    64801 aatggccatc atcttgggga gaaagattat gatgtcatcg gttatcttcc ggaggaacgg
    64861 ggactttatc cgaaagtaac gattcaagac caactgcttt attttgcaga acttagaggg
    64921 aaatcaagaa aagagattga accaaaaatc gacttttgga tggaaaaatt tcaggtaaaa
    64981 gggaaaaaga cggataaagt aaaatctttg tctaaaggaa atcagcaaaa agtccagctg
    65041 atcgccacgt taatccatga acctaaattg atcattttgg atgagccatt cagcgggtta
    65101 gatccggtaa atgctgaatt gctaaaagat ggaatattgg aattgaaaaa acatggttca
    65161 tgtgtcattt tttctagcca caatatggat aatgtagaaa aaatctgcga tcatttgatc
    65221 atgttgcgaa acggaaaaat ggttttgaat ggaaaagtac atgagattcg tgaatcattt
    65281 ggccgtacga agttattctt ggaatctggt ttaagccaac aggaagtaga agaaatcgaa
    65341 ggcgtgaaaa aagtgatcct tcatgaagac aatacgttag agattacctt agaagatcct
    65401 gaagctggga aagaaatctt tactcgtgcg actcagttcg gctacattcc tatgtttaac
    65461 cagcaaccgc caactttgga agagattttc aaattgaaag caggtgaaat cgatgcgtaa
    65521 gttttggatt attaccaaag atgtctattt aaaaaatgtt aagtcgattt ctttcttgat
    65581 catgatatta gtccctttta tcatgctggg tatcatttat gtagcaggaa actttgctca
    65641 acaaaatagt gatgtcaata aaatcggcgt attggctgat aatgagcaaa tcagtcagca
    65701 aatgagccaa gtcaaaacag atgattttga gttcaaagca gttgattctg aagaaaaagc
    65761 acaaaaagag ctttcggaag aaaaaatcga tgcgtattta gtagtctcaa ctgagaatga
    65821 taagataaat gggatgcttt atagcgaaaa ttcattagga caaagtacac aactactgat
    65881 acaacaacaa ctgactggct tgcaatcgat gcttcgagcg agtcaattag gcatttcacc
    65941 agaagaagta gctagcttga gccaacaagc aagtttgact cgacaaaaag tcaattttga
    66001 ttcaaaagga aaaatgacag tcggagaaga taactcgaca gtccaatacg tcgtaagtta
    66061 tgtagcaacg attgtcttgt tcattattat tttgacgtat gcgcagatca ttgcacaaga
    66121 gatcgcttct gaaaaaggca cgcggatcat ggaagtgatc ctgtccagta cgactgcaca
    66181 aaagcatttt tacggaaaat taacaggtgt tttacttgtt gcattaacgc aaatggcatt
    66241 atacggtatt atttttggta taggatacag tcaattcaaa gatatggaaa tggtcaaaaa
    66301 tatattagac ggtatctcat tggataactt gattggacca ttcttgtggt attctcttct
    66361 attcatgatc tttggcattt tgattttttc tgttttagca gctttatgtg gctctttggt
    66421 caacaaagca gaagatacag caaaagcaat tttgccagtg acttatctat ctctaggcgg
    66481 atacatgctt ggattgatac taggagcttc agatccaaac aatatcgtta ttcggatcac
    66541 ttcgtatatt ccattcttat cttcatatat tatgccggtt cgcttagcaa atgagacagt
    66601 cggtatgggt ggagcattga tttccttgtt ggtacttgta gccgtaacat tcttattgat
    66661 gatcttgtct gcaaacatgt acaaatcgaa tgtactcgtt tatagcgaag gcggattatg
    66721 gagttcattg aaacaatcga tttcaattat gaggaatgaa cgaaaaaaag cataaaacaa
    66781 tcctaaaata cagaaggaag ctggacatct attgttccca gcttcttttt gtatagacct
    66841 attttattta ttttactata ttggatatat attcattgaa aatagtgtat aacaacttta
    66901 taatattgag tataccaatt tttggaggcg ttttaatgga ccgttattta gatttacttt
    66961 cagaaaaatt cccctcaacg gaggatgtca tcacggaaat catcaatctc gaagcaattt
    67021 tgcagcttcc aaaaggaaca gagttatttt tgagtgatat acatggcgaa tttcctgctt
    67081 ttgatcatat tctgcgtatc ggttcaggaa atcttaaaga aaagatcaaa gacctttttt
    67141 ctgaacaaat gacggaaacg gatatcagcc aattcactat ttttacggct tatccagaat
    67201 atgcattaac gactgattgg tacaaagaac aagataaatc gcagctgatc catcatttga
    67261 tcgatctttt acggtttacg acagtcaaat atacccggtc aaaagttcga aaaggattgc
    67321 cgaaagaata tagctatatc attgaggaac tcttgtatat cgatgaccgt atcaatggaa
    67381 aaaaagacta tgtaaaaaaa atcattgaac aacttgtttt gatgaaggaa gaagaaaaat
    67441 ttttaacgaa acttgcacag acgatccaaa aatctgtcat cgatcatttg catatcgttg
    67501 gagatatttt tgaccgagga actcaagcag ccaaagtgat ggatcgaatc atggattttt
    67561 cttctgtaga tatccaatgg ggaaatcatg atattttgtg gattggtgcg tattgcggct
    67621 ctgaggcatg tttactgaca cttttacgga ttgcagcacg ctataattat ttatttgaat
    67681 tagagaaaga atatgggttg aatttacgtc cattgttttc ttttgctcat caaacttatc
    67741 agaagaatcc agtatttgcg cctaaaaaca gtaaaaatct atccgaaaga gagcaagaag
    67801 aattagaaaa aatccatcag gcactttcta tccttcaatt caaatcagaa catcagttat
    67861 tggatcgtcg acctgaattt aaaatggacg atcgtaaatt gctggaaaaa atcgactatg
    67921 aagcatcaac gattgattta gaaggtcagc tctatgagtt gaaaggaact tgttttcaaa
    67981 cgatccagcc agatgatcca aaaaaattct tggaagagga acaaaaagtg attgatagtt
    68041 tgatgtattc attccagcac tctttgagaa tgcaaaaaca tatgacgttt ttgatcgaaa
    68101 aagggggaat gtatctcacg aacaatcagc atgtgctgtt tcatggctgt atacctgtag
    68161 acgagaaggg acagctctta gcatttgaat tagaccaatc ttatcgcgga aaagaactgc
    68221 tgggcttttt tgaaaaacag ataactgaaa gcgcaaaaga tctgactgca aaagaagatt
    68281 tagcaaccga tttgatttgg tatgcgtgga gtgggccatt ttcgccttta ttcggcaaga
    68341 gtaaaatggc gacttttgaa cgttattttc tcacagagcc tcatacgcac gtcgagaaaa
    68401 gcaatcctta ttatcacttg cgagatgaag agtggttcag tgaaaaaatt ttagcagaat
    68461 tcgacacaaa agaagaaggg tcagcaatca ttaatgggca cacgccagta aaagtaaaaa
    68521 aaggggagtc accgatcaaa gcaaatggaa aagtatttgt cattgacgga ggtttatcca
    68581 aagcttatca aaaaacgaca ggaattgccg gttattcact attatgcaat tcttatggtt
    68641 tccaaatcgt gacacattat ccgtttttgc ctattgaaca acaatttgca aaaaaatccg
    68701 accaaacaaa tgtgaaaaaa gtaatcgaac agcaactacc acgcaaactc aatcgtgata
    68761 caacaaaagg tatggaactg cagcagcaga ttacccagct caaaaggctg ttggactatc
    68821 gaaaggacga ttgagaagaa ttccagtgaa cattgttcca tagactggag actgagacaa
    68881 aagtcgtgtc gcagtctctt tttccggata aacggtgttc ttctgccaac tcctcggtca
    68941 caagtcacac tattcaacaa acatgaaaag ctgttttttg aaattgctcc ttgtgactca
    69001 gagttgaacg gcaggctcac gacctcttgg tataaacggt gttcaaaagc cagtttctcg
    69061 gtattaagcc aaatttatgc aaaaatgtga aaagccattt tcacaaaatt tttcttaata
    69121 ctcgaaacta aacagctttt tcacaacccc ctcagaaagt ctattaaaat tcattcacaa
    69181 agaaatcgaa taagcgctgt tcagatggat gtacacggtg ggtaagttcc ggatgccatt
    69241 gaacaccgag gattttatgc atatcatctt tgctttgaac cgcttcaatg agtccatcgt
    69301 tagaaaaagc gatggctttt aataaaggtg aaagatcttt gactgcctga tgatggtaag
    69361 aattcacaaa atatggatcg gggagaaggt tgcttaacaa actgtctgaa acaatcttga
    69421 cttcgtgagt cgtaaattgc ggggcagtgg gctgttgttc atgttttact gaccactttg
    69481 gatataatga aagatcttga taaagtgtac cttccaaaac gacattcaat agttggagtc
    69541 cccggcagac tgcaaaaatt ggttttcttt gtttcaatgc ttccaagatc agtgcctgtt
    69601 caaattggtc tcgttgaata tttgtttccg ttagctttgg atgaggatct tccatgtaaa
    69661 gttgtggact gacatcttga ccacctgcaa gaataagttt gtcgatttgt ccaatcagtt
    69721 gaggagctga atctggagac atgactggca gaataagagg caatccttga gcatctaaaa
    69781 ctgcatccac gaatccttgc ggtgtatagc tcacttgatt tccttggaaa gtatctgttg
    69841 ctcgaatcag ttgatttccg gcaatgccga tgattggttt catttgtatt ccccctaaag
    69901 tagacttatt gtaacaagga tttaaaaaaa attaaactat gtaagacttg cccctatact
    69961 tatctgttct tgctgtgtta ctatctgtaa agagaaattt cgtgtgaaat tcatgacgat
    70021 agttgaaaat attgcttaat ttgttataat aaaaagtaag cagaaataaa aaggttgggc
    70081 gtaagcttca aggatctagt tcttcaaggg gtgagaagga cattttattg aaggggcctg
    70141 cctatactaa gttatcttta gaggtacata ctttcaatga aaaaagaaag catgtacctc
    70201 ttttttaaat cgaaaggaag tgaagcaagt gttagaagct ttggaacaaa tccgaaaagc
    70261 agaagaagaa aatgaaaagc gtgctcaaac actgcggcag cagctgaaga tctatgcaac
    70321 agaaaaagag caggaattgg aaacgatcca aacaaactat cgacaacaac taaaacagtt
    70381 ggtggaagaa aaagaacaat ttgaaataca agaattagaa aaagaaaaaa tgaaattgaa
    70441 agcagaagca gacaaggtgc aagcaacttt gaaagatcaa tatcaaaagc atcagagtca
    70501 agcgatcggt gcgatcattg aaagggtgaa agaaacttat ggccgtcact aagatggaaa
    70561 aagtgaccct catttcagat aaaagaaatc aggagaggat tttacaagca gtacaaggaa
    70621 tccaaaacgt tgaaatccgg gatctgtatc aaaatagaac aaacaaccag tgggtggaga
    70681 agtattttcc agataccacg attattgata aagaagcaaa attaagcgct ttaggtaatc
    70741 ggttgaaaga catccaagaa gctatccaat tcatacaaca ccacggcgat agccgtcaaa
    70801 agaaactcca tttgaaacgt caagaacttt ccttacaaga tttggaagcc aattattccg
    70861 aagaaaattt cataaataaa ttgaaagaag tccttgattt aaaagaaaag tgggaacaac
    70921 taactgaaga acgtgatcgt ttagaagaag aggaagaatg gcttcttcat tggcaacagc
    70981 tggatattgc tccaagtatg tatgcaagta agacgaccat ttttgagatg gggactgtga
    71041 gtgcagcaaa ttttgaaagt ttcaaggaag aactgagtaa gcttgatgac gtttatatgg
    71101 aagaaataga ttatacgcca aaacaagttt atctttcgta tgttgcttta aaaaaatcag
    71161 ttgctgttat agaagaaatt gctgggaaat acgggttcaa taaagaaacg tatccttatg
    71221 aacaaaatcc taaagaaaaa ctgcaagaga ccaagcagca attatccatt gttcacgagc
    71281 agcaaaagaa gataacgaca gcgttaggtc agtgcagtgg ctatatccaa gaatttgaat
    71341 gggtagaaga agtcacactt gccgttgcag aacgagaaaa aataaaagaa cggtttatcc
    71401 atgcgactta tctgatcgtt ttgcaaggtt gggtagatgc agaagaaaaa cagaatttgc
    71461 tgcatgtgtt aaacgaaacc gtatcagaag aagatatata cgtcagtttc gaaacaccaa
    71521 actcagaaga gattcagcag gaagtcccta ctaaattgaa aaaccatccg cttgtcgaac
    71581 cttttgaatt gctgactgaa atgtacagtc tgccaaaata tgaagaagta gatccaacac
    71641 cttggatgac accattttat cttgtcttct tcgggatgat ggtcgcagat gttggttatg
    71701 gtttgctgat gctcattggg acaatactag ctcaaaaact acttgttcta ccacgcggga
    71761 tgaaacgttt cgtaaaattc tttgagattc tctcgatacc atcgatcatc tggggattga
    71821 tctacagttc atttttcgga cagtcattac caaaagaact gtttggcatc cgcttgcctt
    71881 tcccaatcct atctacgacg gatgacgtca atacgatttt gattttatcc gtgattttcg
    71941 gtctgataca gattttggtt ggattatttg tggcagcaaa ggaaaatatc aggagaaaag
    72001 attacttgag tgctgtcagt gatggatttg cctggcaagg gatcctaatt gggatcgtta
    72061 ttgcgttggt tggtgccatg ttgataaaaa atacagcatt tgtttacctt ggcgctgggc
    72121 tatcgatcat tgctgcctta tgtatcttga tcgttccgat tatccaaacg ccgtctaaag
    72181 tcaaaggtgc tgccaaaggt gcgtataatc tttacggact gaccggctat atcggtgatt
    72241 tagtcagtta tacacgtttg atggcattgg gtatttcagg cggaagtatt ggagcggcat
    72301 tcaatatgct agttgctttc atgccgccag ctgctcgatt cagtgtaggg atccttttga
    72361 tcatcgcttt acacgcactg aatatgtttt tgacactgct aagtgcctat gtccatggcg
    72421 cacgattgca gtatgtcgaa ttttttggga agttttatac aggaggcgga cgtgcctttg
    72481 atccgctgaa aacggcggaa aaatacgtca acatcaatca caagaaaaaa aacaataaat
    72541 aattggagga tttttatata atgatggatt acttaattag tcaaaatggt ggaatggtat
    72601 ttgcggtatt agcgatggca acagcgacga ttttttcagg gatcggttca gctaaaggtg
    72661 ttggaatgac aggtgaggca gcagcagcat tgacaacaag tcaacccgaa aaattcgggc
    72721 aggctctgat tctgcaattg cttccaggta cgcaaggttt gtatggattc gttattgcct
    72781 ttttgatttt tatcaactta ggaaatgaca tgtcagttgt acaaggactg aactttctag
    72841 gtgcttctct gccgattgct tttacaggct tgttttcagg tattgcccaa ggaaaagtcg
    72901 cagcggcagg tattcaaatt ttagcgaaaa aacctgaaca tgctacaaaa ggaatcattt
    72961 ttgctgcgat ggttgaaaca tacgcgattt taggtttcgt tatttccttc ctattagtgt
    73021 tgaatgccta agcataaagg aggaaaagca gatgaacgcc attgaaaaaa tcatctctca
    73081 gatgaacgaa gcagcagagc aggaaagagc ggcgttagaa caagaagagc gaatgaagat
    73141 cgatcaaaac tttgaacaaa aacgtacgca agttgaaaca gaacatcaaa aacaaaaaga
    73201 aaaacaaatc gaattactcg aaaaaaaata ccgtcagcta aggaatcgcc agcaagtaga
    73261 agtacgacaa gaaaatttga atgcgaagca ggaattttta agacgattgt ttgcagatgc
    73321 ggtaactgaa atggaaaatt gggatgaatc tgaacaaatc cagtttatca aaaatgcatt
    73381 gtattcatta cctttgacag gaaaagtagc attcattgct ggagaaaaat cagcagccta
    73441 tctttctcag acgttgttgg atgaatggaa caatgaactt ccctttatga tggttttaag
    73501 tgatgaaact gttgctgatc aagcgggttt tctgataaac gatcaaggag ttcagtataa
    73561 ttttcttttc agcagccttg tacaagatat ccaaggaacg atgagttttg agattgccaa
    73621 tcaattattc gaataaggag ggatcagtgt atggaatacc acgaactaaa tcccttgatt
    73681 cgcggaagag agcttgaact tttgtccaat gagacatttg aacggatgat tcaaacaaat
    73741 tctgtcgaag cacttggtga aatattgaaa tccacgattt acagtccata tatttatgac
    73801 ggatatgaat atgacttcga acagaatctt ttaaaggagc agagccgtct atttcgctgg
    73861 ttaaaggaat cagcaccgga gcctgaaatc gtttggatct atacgatgcg ttatactttc
    73921 cataatctga aggttttgac aaaagctgag atgacaaatc aaaatctgga ccatttgtat
    73981 atcgacgatg gattttattc attagaaacc ttgaaggatg ccattcatac gcaagtttca
    74041 aatgaacttc ctgaaagcat tatggacagt atacgagaag tacgtgatta ttttgaagag
    74101 tctaccattc ttcagggaat tgacgtgatt tatgatcgac agtttttgac agagcagcga
    74161 cggcttgccg ataagctagg atatcaagaa ttgctgacag aagtcattgc ttttattgac
    74221 ttgaccaata tcacaacgat ggctcgagga atattgcaga aaagaacata tgggttcatg
    74281 acgacggtac tttccagctc gggaagtatc gaaaaagaag tatttttgaa ctttgtagat
    74341 aaagatatgg aagattacac gaattttcta ttagagacag attatgctga ttttctgcgc
    74401 cctgtcatcc gtgagggaaa tattgatctc gtaaagcttg aacagttgaa agatgattat
    74461 ctaagttcat tgtatcaaga agcacaaacc caggctttcg gaccactgcc actactagcc
    74521 tttttgaacg caaaagaggt agaaagcaaa aaccttcgtt tactggttat cggcaaaaga
    74581 agccatttcg aatcagaaac aatcagaaag cgggtgagac aagtctatga cgcataagat
    74641 cggtgtagtt ggcgacaaag attctgtttt gccattcaaa ttgtttggct ttgatgttcg
    74701 ttatggtaca accaagcaaa ccgttcgtca ggcaattgaa gaaatggcaa agaatgagta
    74761 tggcgtgatt tatgtcacag agcaatgtgc agcattgagc ccagaaacga tcgaacgtta
    74821 caaggaacaa atgatacctg ctatcgtatt gattcccaat catcaaggat cattagggat
    74881 agggctggaa gaaattcaaa aaaacgtaga aaaagcagta ggtcaaaata tcttatagta
    74941 tgaaaaggag atagaaattt tgcaaattgg aaaaatcata aaagtctccg gacctcttgt
    75001 aatggctgag aacatgtctg atgccagtat ccaagacatg tgtctagtgg gagatctagg
    75061 agttatcgga gaaattatcg agatgcgtgg cgatgtggcg tctattcaag tatatgaaga
    75121 gacttctgga attggtccag gcgaaccggt tcgctctact ggtgaagctt tatctgttga
    75181 attaggacca gggatcattt cacaaatgtt tgacggaatc caacggccat tagatacctt
    75241 tatggaaatc acacaaagta atttcttagg gcgcggagtt caattgcccg cattggacca
    75301 tgagaaaaaa tggtggttcg aaccaacagt agaagccgga gaaacggtga gtgctggaga
    75361 tgttatcggg atcgtagaag aaacaaaagt tataaaacat aaaatcatgg tgccaaatgg
    75421 gataaaagga acgatcaaaa caatcgaaaa aggttcattc actattgatg aaacagtatg
    75481 tgtcattgaa accgaaaatg gtgacaaaaa tttgacgatg cttcaaaaat ggccagtaag
    75541 acgtagtcgg ccaatcaaag aaaaattaaa cccggatgca cccatgatca ctggacagcg
    75601 agtgattgat acattcttcc cagtgacaaa aggaggagca gcagctgtac ctggtccttt
    75661 tggtgcaggg aaaacagtcg ttcagcatca aattgcaaaa tgggccgatg tggacatggt
    75721 tgtctatgtg ggatgtggcg agcgtggaaa tgagatgacg gatgttttaa atgaattccc
    75781 tgaattgatt gaccctaata caggagaatc gttgatggaa cgtacggtat tgattgctaa
    75841 tacatcaaac atgccagtag cagctcgaga agcttctatc tatacgggaa tcacaattgc
    75901 ggaatatttc cgtgacatgg gttatgacgt tgctatcatg gcagactcca cttcacgatg
    75961 ggcagaagca cttcgtgaga tgagcggacg tttggaagaa atgcctggtg atgaaggtta
    76021 tccagcttat cttggttcac ggcttgcgga atactatgaa cgatctggaa gagtcattgc
    76081 attaggatca gaaggtcgcg aaggaagtat aaccgcaatc agtgctgtat ccccgtctgg
    76141 aggggatatt tcggaaccag tcacacaaaa tacattgcgg gtcgtaaaag tattctgggg
    76201 tcttgattcc agtttagccc aaaaaagaca ttttccttcg atcgattgga tacaaagcta
    76261 ttctctttat tcaacagaag tagggaagta tatggatcat atccttcaag ctgactgggc
    76321 atccatggtc accgagggca tgcgtatttt gcaggaagaa cagcagctga atgaaatcgt
    76381 gcgtttggta gggattgatt ccctttcaga taatgaccgt ctgacattag aagtggcaaa
    76441 atccattcgt gaagattatt tgcagcaaaa tgcttttgat gatgtcgata cattcacttc
    76501 aagagagaaa caattcaaaa tgttgaagat gatcttgacc tttggtgaag aaggacgccg
    76561 tgcgttgtcg ttaggtgctt atttaagtga gatcatggac ggtaccgtat cgattcgtga
    76621 aaggatcgga cgaagcaaat atatcccgga aacagaatta gaaaaactag atcaaattat
    76681 tggtgaaatc aagcaaacga tgcaaacgat cgtttcagaa ggaggcatga gcaatgatta
    76741 aagaatatcg tacgatcggt gaagtcgtcg gtccattgat ggcggttgaa aaagttgctg
    76801 gtgtcaaata tgaagaatta atcgaagtcc gtatgcaaaa tggcgagatt cgtcgtggac
    76861 aagtattgga agtccaagaa gataaagcaa tggtccaaat attcgaagga acaagtggta
    76921 tcaatttacg tgactcttct gtacgatttt taggccatcc tttagaacta ggtgtatcgg
    76981 aagacatgat cggtcgagta ttcgatggtt tgggacgacc gaaagataac ggaccagaga
    77041 tcctgcctga aaagcatttg gatattaacg gagaagtaat caatccagta gctcgggatt
    77101 atccagatga gtttatccaa acaggtatct ctgcaatcga tcatttgaat acattagttc
    77161 gtgggcaaaa attaccagta ttttctggct ctggtcttcc tcataaagaa ttagctgctc
    77221 agatcgcgcg acaagcaacg gtactcgatt catcagatga tttcgccgta gtctttgctg
    77281 ctattggaat cacttttgaa gaagctgaat ttttcatgga agattttcgt caaacgggcg
    77341 caatcgaccg ttctgtcatg tttatgaatt tagcaaacga ccctgcaatc gaacgtatcg
    77401 ctactcctcg tatggctttg actgctgcag aatatcttgc ttatgaaaag ggaatgcatg
    77461 ttttggttat catgacagac atgaccaact atgcagaggc attgcgagag atttctgcag
    77521 cacggcgaga agttccagga agaagaggat atcctgggta tctttacacg aacttagcta
    77581 ctttattcga acgagcagga agaatccgcg gactaaaagg atcggttact caaattccga
    77641 ttctaacaat gccagaagac gataaaactc atccaatccc tgacttgact ggttatatta
    77701 cagaaggaca gatcatcttg actagagagc tttacaagag tgggattcag ccaccaattg
    77761 atgtactccc gtctctttcg cggttaaaag ataagggaac tggacccgga aagacaagag
    77821 aagaccatgc agctacgatg aatcagcttt ttgcagccta tgcacaagga aaacaggcaa
    77881 aagaattagc cgtagtttta ggtgaatctg ctttatctga tgtagacaag atctatgcga
    77941 agtttgctga gcggtttgaa aaagaatatg tcaatcaagg attctacacg aaccgttcga
    78001 ttactgaaac acttgatcta gggtgggaac tgctatcgat gttgccaaga accgaattaa
    78061 aacgaatcaa agacgacatg ctggacaaat atctgccaga agggaagtga gttctgatgg
    78121 cacgattgaa tgtgaatccg acccgcatgg aattgactcg attgaaaaaa cagttgacaa
    78181 ctgccacaag agggcataaa ttattaaaag ataagcaaga tgaactgatg cgtcaattca
    78241 tcctgttgat tcgaaagaac aaccagctgc gtcaagaaat ggaagagtct atgacagaag
    78301 caatgtctga ttttgtattg gcaaatgctt cgatcacgga acctttcatc gaagaattat
    78361 ttgttttgcc ggcggaaaac gttgatttgt ctatcgtaga caaaaatatc atgagtgtaa
    78421 aagtacctgt gatgaatttt gaatatgatg aacagctgac agacacacct ttggaatacg
    78481 ggtatttgaa ttccagtgcc gaactggatc ggtcaatcga tcggtttact accctgcttc
    78541 caaaactttt ggaactgaca gaaatcgaaa aaacttgtca actgatggcg agtgaaatcg
    78601 aaaagacacg tcggcgagtc aatgcattag aatatatgac gatccctcaa ttagaagaaa
    78661 cgatctatta tattcgtatg aagctggaag aaaacgagcg cgcagaagta acaaggttga
    78721 tcaaagtaaa aaatatgggt accactgact aagtggtatc tttttttaaa agaggaaaac
    78781 gatgattaaa caaagcaaac aaataaagaa acgtttgccg gctgttcagc ttctcgcatt
    78841 aggatttttt ctcctgattt tagttggcgg cggcctactt accctaccat tttttagtaa
    78901 tagtgggcat gggacaaatt ttatcgatgc gcttttcact gcaacttctg ctgtctgtgt
    78961 aacgggattg acaacattga atacagcaga gcattggaac agtgctggtc aatttttgat
    79021 catgcttttg attgagatcg gcggtcttgg ttttatgatg gttccgattc tatgctttgc
    79081 attgataaag aagaaagtca gtctcagcac acgtattata ttaaaagaag cgctgaatct
    79141 agaagaagta tcaggtgtga tgaagctcat gctttacatc ctaaaattgg cctttgtgat
    79201 ccaattgatt ggtacggttg ctttatcttt tgtatttgtg cctgaatttg gctggttgaa
    79261 aggtatctgg tacagtttgt tccatgcaat ctctagtttt tgtaatgcag ggtttgattt
    79321 gttaggagac agtttagcca atcaccagca aaatgtttat ttgatcatgg tggtatctgc
    79381 tttgatcatt tctggtgggt taggcttcat cgtatggcgt gatttactgg aatatcatca
    79441 gaaaaagaag atgacgattc attcaaaaat cgcattaacc gttacaggta cccttttatt
    79501 aggcggattc gttgtgttct ttttcacaga gcgcaatggg gcaacgctag tggaagggaa
    79561 tatgtttcaa cgattggcaa acaccttttt tatgagtgtg acacctagaa cggctggata
    79621 ttattcagtt gattacctcc atatgagcca tgcaggtctg attttaacga tgtttttgat
    79681 gtacatcggc ggaacatctg ggtcgacggc cggcggattg aaaacaacta cgttaggtgt
    79741 gttgctgatc cagatgcgtt cgatgttgaa aggacgtacg agagcggaag catttggccg
    79801 taccatccga caaggcgcag tgttgcgggc acttacttta ttttttgtta cgttgacgtt
    79861 gtgtgtagtc gccatcatga ttttatcggt gactgaaacg atacctaaaa cttctggcat
    79921 cgaatatatt gcttttgagg tcttctctgc gtttggtaca gtaggtctta cgatgggatt
    79981 gacgccagac ttgactgcaa tagggaaatt gatcattata gcgcttatgt acattggacg
    80041 agttggtgta ttgactgtgg tcttctctct gatgacaaaa gcacaaagaa cacaatcaaa
    80101 atacaaatat ccagaagaaa gtgtcatgat tggataattt catcttctga cagaaaccta
    80161 gtgatttagt aaaataagaa aataaaataa tttttcttgc ttcttggata ctttaagtgc
    80221 aaaatgttcg tttatttttt gaggcactac ccgttgttga acctcgggta gtgcctcttt
    80281 tttattgaaa ggaatcaata agatttgatt cctttattta tcaataggtt ataattcata
    80341 tttttttatt ttttctttta cgatacttag tccagaagct aaaatttcaa ggttattaga
    80401 ggatagggaa attcgaacga atgcatctgg ttgcgtacgt gtagtaaagc gtctggaatg
    80461 ataaagtcgg ataccgttag caagaaagtc attctcaatt atcttagggt caatctcagg
    80521 atcaactgga agaattcgat agtaagggac acgattcgtt ggtttttcta ctttgaaaag
    80581 agaatcaaaa agctgattgg ctctttttgt aagacttaat ttagtttcta agatcctatt
    80641 tgcttcattt gaatggagga tttgagtgat gacttccaca tctaatccag aagttttcac
    80701 atttatatta aaaattgctt gttctatctt gctttggaca tgtactggaa ctacaagata
    80761 agcaactcgc aatccagaac aaataaattt tgtcattcca gctaagtaga ttgtttggtt
    80821 aggtaataaa ttttggaaag gaggaatgat cgtatgttga tagtaagttg ttaaaaatga
    80881 atggatatca tcttcaataa cccatagacc ttctttttca atcacttcgg ctaattgctc
    80941 tcgtcttttg tgagagattt gaaaccctat aggattatta caagaaggca taagaaagac
    81001 accatgaatc ttcttttttc tacattcctg aatcaatata tcaggtcgca ttccttgctc
    81061 gtcaaaatca attggaacga tctctaaatg atataactga gccaattcaa tgaaattagc
    81121 gtatgtatat cggtctgttg ctattctatc acctggagag aaaagtgcag aaagtgtgat
    81181 agccaatcca ttttgaacac cggaaacaat agatagagat tctaaggacg gaatgactcc
    81241 ttgagttttt aaccaatttg ctgcagtagt caattgaaaa tttgtgcctt tgggatcttg
    81301 gtaattaagc aaaccaacaa gatttgggtt attactagtt gattgaataa acgggacaac
    81361 gaatttatta cattcttcaa aagaactaac cagaccaaaa tcaatgatat gttcggttac
    81421 ttcattggta gagatggtga tggactcaaa gacattggga gaaataaatg tgccacttcc
    81481 aatattcgta tacagcaaac ctttctcaat tccatattta taagccttgc caacggtagt
    81541 aaaatttaaa tctaaataat cagctagctc tctttgggag ggtaactgag tgtttttctg
    81601 taatttattc tttaaaatat cttgttctaa ttgttgaatc aacgatcgat aataaggacg
    81661 cttcaatttt tgtttgtctg gtcgccaagt taacgggtaa ttgtcataag aattaatagg
    81721 cattttctcc actccttaaa attgtatacc atacaatttt accattgatt gtattgattt
    81781 tagaagttaa tcttttgtga ggagggaatt gtctatgaaa attattaatt ttgaggaagt
    81841 agtagcttct tttagttttg aagaagcgat tcaagtaatg aaaaaatgtt tttttgatta
    81901 tgaaagtggt aaaatcagcc aaaatcctcg attggtggaa attttacctg acggaaaagg
    81961 caaaaatatg tttgcgatga tgcctgctta tttgggggag aacagatatt ttggcacaaa
    82021 agtcattacc gcttttccgg ataatcatca gtatcattta ccttctcatt taggagagat
    82081 tttcttgttt gatgctcaaa acggactacc caaagcattg ataaacgcaa atgcagtcac
    82141 ctggattcga acagctgctg tatctgcgct ggcaacagat tacttagcaa atccgcatgc
    82201 agaaacactt gctttaattg gagctggtca acaagcattg tcgcatttga ctgcgatttc
    82261 taccattcgt cccatcacta cagtgtttgt ttacgatatt ttagaagaaa gacgaaatac
    82321 ttttatcgct aaagctaaaa aacagtatcc taaaataacg tttataaatg caatatcagt
    82381 agaagatgca gtacgtccag cggaaatcat ttgtacgttg acctctagta aagaggcatt
    82441 tcttcaaaaa gagtgggtaa gggaagacgc acatatcaat gctgtgggca catttactcc
    82501 tgatacaaga gagataagta catcgttgat ggaaacttct caaatctatg tagatgatta
    82561 ctcagctgcc ttaacagaaa gcggggacct gcttatagcc atggcagaag gagatttaga
    82621 ggaatcttgt attgttggta cattaggcga attagtttct gagaaaaaaa cattttataa
    82681 aggagaatcg aggccgacga ttttcgacgc agttggtcta gctattgaag atctttgttg
    82741 tgcagaatat atttataaca aattagagaa aggggcttta aaatgaactt agattattac
    82801 gtagttgatg catttgcaga tgaggtgttc aaaggaaatc cagcagcggt ttatgtgcta
    82861 gaagaatggc tgccagaagg tacgatgcaa aaaattgcca ttgaaaacaa tttatctgaa
    82921 acagcattta cagtgaagaa aaaccaagaa tttgagctta gatggtttac gccagatcga
    82981 gaaatcgatc tttgtggtca cgcgacatta gcaacagcat ttgttttatt taactattac
    83041 aaaatacctg atgaaacgat taaattttct actcaaagcg gtaatctatt tgtgacaaga
    83101 attaaagatt attattacat ggattttcct agtattatgc cgaaaaaagt gccgatattg
    83161 tctgaatatg aagaagcgat tggggctaag attaaagaag cctacttagc acgtgattta
    83221 tttttcgtat tagaagatga aaaaacggtg gctaaattgc agccagattt tacagctatc
    83281 aaaaattttg aattaggaat aggagtcatc gtgacagcag aaagtgtgca aaaagacttt
    83341 gtttctagaa ccttctttcc aaaattaaca atcaatgaag atccagtatg tggatcagca
    83401 cattctaatc ttattcctta ttgggcagaa agaatgaata aaacaaaatt gtcagcttat
    83461 caaatgtcat caaggggcgg ggatctagaa tgtgaattaa aagaagatcg tgtgataata
    83521 ggaggaaaag cagttttgtt ttctaaaggt acctcgttta tttgatttct ttcaaatgaa
    83581 ttaaaaataa attggtggag agtggcaacc ttatagctac aatggttgtt aaaaaaagac
    83641 gcaaactttt tcaatttaat gaaaagtttg cgtctcattt taattattgg tgtttgtttt
    83701 ttattcaatc aagagtaaaa tgccccatac taactatcct cggatgactt cgattttata
    83761 accatcaggg tcaatgacaa agtagtaaga aggcgcagtg ccaggtaatc cttttaagtc
    83821 agtaatctca agaccagcag ctttatgttg ctcgtgtaat ttttctagat catcagctgc
    83881 tatagcgata tgaccatagc cgtctcctag atcatacgca ccatgatcat agttgtaagt
    83941 caactctaat tcatagtcat ccccaggaag tgtcaaataa acaagtgtaa atttgttttc
    84001 tggaaaatca cggcggcggc tttcttcaaa accaaatgcc ttttgataaa attcgattga
    84061 tgcttcaaga tctttcactc gaacacatgt gtgagccatt ttcatagatt catctctcct
    84121 tttcctttta ctcaatcata acaaaaagaa gtaaggaaat agttgatttg tgcttgttca
    84181 tgagaaattt ctcatgtaaa atggatagaa aataaaactg ttaaggtgga aactattcat
    84241 ggataaacca atttttggtg aaaaaaagca atttgctgat tatcaaaccc gttatgcagc
    84301 atatattgtc atagaaagag atcagcagat tgcagtaatc gaggctccaa atggtgcttt
    84361 ttttcttcct ggcggggaaa ttgaaggaga agagacgaaa gaagaagcga ttgtccgtga
    84421 gctgatagaa gaaatgggaa ttgtggcaga aatttcttct tatctgggag aagctgatga
    84481 gtatttttac tcgaattatc gtgcaactta ttattataat ccaggatatt tctttgttgc
    84541 tgattcttgg aagcgtatag gagaaccaac tgaaaagacc aataaaattt ggtgggtgag
    84601 ccctcaagaa gcgcttgtga aattgaaacg tggtagccac cgatgggcag tcgagagatg
    84661 gatcgaaaaa aataaaaact gaaagaaagc gagtagatca gctttctctc agttttttta
    84721 tttattacag tacatatttt ttgattgctt cagctacacc gtgctcgtcg tttgatgaag
    84781 tgatgacatt tgctgcttct ttgacaagag aaacggcatt tcccattgct actcctagac
    84841 cagcatattc aatcatggat aagtcgttct cgttatctcc gatagccatg atttcatctt
    84901 gatcaatacc aaggtgctgt gcgagattcg caactgccgc acctttactt gcttctttat
    84961 ttagtacttc gaagtaatag ggcgcacttt tgaccgttgt gtatttatca cggaaagttt
    85021 gcggtaaacg cgcaattgct gcatctaaaa tttctggttc gtcgatcatc atcattttga
    85081 cgatgttcat gtctggtgtc atttcttcag gtgttcgata ttttagcggc atcttgacta
    85141 aacttgcttc gtggatcgta taagcgctga tatctcgatt aggcgtgtag atcgctttgt
    85201 catcgatcga atggagatga ctgccgacac ggcgtgccat cacttcgatc tctaggaaat
    85261 cttcatgtgt cagtccgtga cgggcgatga ttttacctga tttcgtttgt tgtacgagtg
    85321 ccccgttata agtaataacg taatcattat cttgaaaaag gttcaactcg tttaactgtt
    85381 cctggacacc tggtaaggga cggccagtgc ataaaacgat cgaaacacct tttgcaacag
    85441 cagcggcaat cgcttctttt acttcttttg ttacttctct tttctcattt aataaagtac
    85501 catcgatgtc gatagcgact agtttgatag acataatttc ctccaatata ttttaattta
    85561 tttcaatcaa tgcgccatta cggatatggc tggcaaattc ttgataagtt tcgtcaaata
    85621 aatcataatg atcacgcaag gacggatcaa ccatttcttt tggaaagaaa aatcgctcat
    85681 ctccttgttc ttgtcccgct aatgcagcaa caagctgact aacctgtgat aattctatca
    85741 aagttccgtc atttcgcaaa atctcgattt gtgtgcgatg tctgccttgt tctgggcgat
    85801 aaaaatcata aggtagatcg tagctagaat tcacagcagt gtaataaaca ggattatatc
    85861 cgaccttttc tactaacaaa gtgagttctt ggactaattt tgaatcccgg ttgccagaaa
    85921 aagtagcaga tttcagtggt ttacgattca aaaaacgttt agctaaatca tttaaaatag
    85981 gatcagcaga ttcagaccat tgagtaaagt aagtgcccaa gaccccatca tcaagtttga
    86041 ggtattcttc taaagtaaag cttccgtcaa gaaatggcag aagtaattga gaatggagtt
    86101 caaaactgct ggcatcttct tgatacaact cgtgtgcgcg atgaagcaga tgctccaaaa
    86161 ttacttccat accacgggaa acaggatgga agtacacttg cacatacatt tgatatcggc
    86221 taacgatata atcttccact gcatgcatgc cactcatgga aaaagcgatc ccgccttcat
    86281 aaggacgaat cacacgtaat attcgggtaa gatcaaatgt tccatattct gttccagtga
    86341 aataagcatc ccgaagcaaa tagtccattc gatctgcatc gatctgacta gaaatcattt
    86401 ggacaacttg tgggttgggg taagtttttt ggatcacact agctaccttt tcaggaaaac
    86461 cttcttctac tcggttaaga atctgataca cttctgtttc tggagaagtg atgatctcta
    86521 cagtgatggc ttcatgattc gtatggaaga tatgttcaaa tgtatgagag taaggaccat
    86581 gaccgacatc atgcaacagt gccgcacata aagtcaccag ccgttcctga tcatcccagc
    86641 ctccgttgcc tattttttct tttgaaaaat ttcgagaaaa gatatcgcag attcgtcttg
    86701 aaatctcata aacgcctaat gaatgagtaa aacggctatg ttctgctccg tgaaaagtga
    86761 aagaagaagt gcctaattgt ttaatgcgtc gtagacgttg gacttctttc gaattgatca
    86821 aatctaagat tacttgatgc tggacatgga tatagttatg gactggatca cgaaaaactt
    86881 tttccatagg cagcatttga tatttataag gggttgtcat aatgtagctc ctttatgtta
    86941 ttacgttgtt ccattctctg gatttggttg ttccattgct ccagctggat ttcttttttt
    87001 agccagtcgg tagaatcctg taaatcactt gcagaataca gcttttcaaa agcttttgca
    87061 aatgcttctt tgacttcttt tacaaaaagg ggttggtcaa gcagttcttc aagtgttgcc
    87121 attgtagcag gatccactgc aggatagcca tttgtaccaa agtcttcttt taaagcagat
    87181 tgataaaatc gcttcatgac ttgcccgcgt ttttcctgat taccgttgac acttaagtac
    87241 atcataacag aaatcccatt tttgatccga cgctgagcga taccggcaaa ttttttgcca
    87301 tggatgctta aatcataagt tccaggacaa taagaatggg tgatttcgaa tgcttgtatc
    87361 ggtgcctttg gaaaagcgta tttagtcaat aggagcattt gctcgtaagc gtcatctatg
    87421 gttatttttt ttgtgtcact ttgggggaaa atcaaagaaa tattcaaaat tccttcatct
    87481 gatacgatcc ctaatccacc tgaatttctg atcactggag cgtaacctgc atctttcagt
    87541 gtttggatcc cgtcacttag aaaaggagtt cgaacatcct tcatacctaa gatgactgtg
    87601 cagtcatatt gccagaaatg taaaaagatt tgctggtgtt ctttagaata ttccgttaat
    87661 atatctgtta atgcaaaagg ggaaaagtcg tttttttgat aaatgtgctg atctagtcga
    87721 atcgcagggt tcattcaacc ggctcctttg tataaattca tattttctac aatattatac
    87781 tctaaaatca aagagttgtt ttggaaaaaa ggttttctgt aaaaatggac aagttggttg
    87841 acaaaacaaa agaaactagg aacaatgtag ctatgagaag taaaggagaa tgaataatgg
    87901 aattatcaca aggaacaccg atttcaatca aattgcgtac aaaagtaaaa cagcaagggg
    87961 aagtgcaaga tttttatttt gatttgaaag ggcaaatggt gacaattggc gatacgctgt
    88021 acatacgtta taaagagatt caggaggaga cgggcgatga gattcctgta acgatcaaat
    88081 tagttccaga tggtcatgta cagctgatcc gtgcaggaga aatgcggatg cgtttgaaat
    88141 ttggctataa agaacggtta gaaacatcct atcgaacacc atacggtatg atccagattg
    88201 ctacttttac gaaagaactg catgttagtt tgaaagaccg tcccacagca gggaaggttc
    88261 gaatcgatta tgatctgttc atgggaccgg aaaaaatcgg cgaatattat ttgaccttgg
    88321 attttacagc gtaaatataa aagaaaagtt tgattttttg tgtctgattt tgtatgataa
    88381 ggagtagact gtgaaaggac gtgtcctgat tggaaattag tgtatttgaa ggtgcaaaca
    88441 aaagcgaatt atcaatgatc gaagtagcac acgcgatctt agaacaacgt ggcgatgtca
    88501 tggatttttc tgatttagct aaccagatcc aaaactatct tgggaaatca gacagtgaaa
    88561 ttcgtgattc actcgcacaa ttttatactg acttgaatat tgacggcagc tttatctcat
    88621 taggggataa tcgttggggc ttgcgttcat ggtatgctat cgattcgatc gatgaagaag
    88681 taaaccatgg aatggacgaa gaggatgaag atactccacg tcgccgtaaa cgcaagaaag
    88741 tcaacgcctt tatcaatgat gatgaagacg cgatcgatta caatgacgat gacccagaag
    88801 atacagatct gacagaagaa gatgacgatg atctgtttga tgacgatgat gatgaagatg
    88861 aagaaatcgc tgcttataat tctgacttgc aagaaatcgg agcagatgac ccgacagatg
    88921 atgaagaaga cttgccagga aatatcgaag aagatttaag tatcatagac gaagacgatg
    88981 atgatgaaga ttatgaagag gaagaatttt ctgactctga aaaagaataa acattatttt
    89041 cttacgagag gttgtgacag agacgatcag cctatcagaa taaggaggtg tgacacgatt
    89101 tttgtcacac cttctttttt gtatataaaa atcccaagta aatacataaa aaataaaaaa
    89161 attgaaactt ttagcgcacc ttgtacgtca tattaagtga ggcagaaagg agtggagaat
    89221 gatttttact ggatataaga aaaaacggca gatcgaaaaa taccgtcacc tgctgaatgg
    89281 actcatcgaa actgattatc aaaaaatgtt ccgtatcacg atgaattacg tacatgataa
    89341 agaagaggcc ttagatgtga tgcaagatag ttttcataaa gccctgaact attttgaaaa
    89401 agaaaaagag atcgagcatt ttagtgcatg gttttatcgg atattgatcc gcacggcatt
    89461 agatagttgg cgcagacaaa aaaggacgcc tgtggactta tttgaaattc aagatatccc
    89521 ccaacagtta cctttagaaa cttccgttgc agagctccat atgattttag ataaaataga
    89581 cagtccggaa aaagagattc tgatcctcta cttttttgaa ggatttcgtt tgaaagaaat
    89641 tgcgactatc ttggatatga atgaaaacac agttaaaacg aaaatgtacc gctcattgaa
    89701 tgctttacgt caaatcctag aatgaaggag agaagagtgc catgtattcc caaaaagaaa
    89761 atttaaaaaa actaaagaaa acttataaag aacaagcaat tcccaaaggg cttaaagagg
    89821 agatccgcca gcgttttatt atcgaagagc aatcatttat aaaagcaaag cggagaaaga
    89881 gacgtctcca agggttcgga gtatctttgg ctatcgtaat gattacaaca agtagccttc
    89941 tttttaatag tcaagttcga agctttgcag aagatttacc catcttagga tcagtcattg
    90001 aattgatctt aggcgaacgc tttactgatc gatctgaaaa aatcgatatt caggtaccga
    90061 agatcaatac acaaaatgag aaagaaaata aaacaattca tggattaaat caaaaatact
    90121 ttcgcgaagg acaagcagat tttgaaaaag ctgaaaaaga atatggaaat tttgaaacgg
    90181 atcattacca agttttggga gattatcaga aaatcgtaga cgataaccgg tttctcgtga
    90241 ttgaaaggca gatcacccaa acagcagcag atagccatgt tgaaaaaaga tacgacacaa
    90301 tcgacaagaa aaacagtgtc cagctctcac ttccactttt attcaaagat gacacctatc
    90361 tatctgtttt gacaaaagaa gtcaaacggc agatggccga acaagtcaag gaagatccat
    90421 ctaagtacta ttggactgag caagatattc aagaagggac gatagaaaaa ccaacacttg
    90481 ttacgcctac acgaagtttt tatttgaaca aagagcatca attagttttg actttttctc
    90541 aatacgaaat tgctcctggt tatatgggta caccagaatt tgtcattcct aagtccgtga
    90601 caaaaacgat tttggcatcg gaagattatt tggatcatta gacgagaagt agttgcgact
    90661 agcagtttca attttcaagt aagtacaagt aaataataag aagagaaaaa gagaaagaag
    90721 agatatagtg aaaagaaatt atttagttat cagtattatt gctttatccg tgcttttgtt
    90781 tttcgaaatt acttcggtgg cctccttgat caccgaagta aaaggacaaa cacactcttc
    90841 ggagcattcg tcacaatctt tcaaacaatc agaacaatca accattaaaa gccaatcaac
    90901 tgaaacagct aacgtcaaag aagccattca agaatcagcg gaaaaggtac aaagtcagtc
    90961 atcacaatca acacaagaca gtacaaaaac gagccgagat ccggctgtca aaagcgtcgc
    91021 aatcagcttt gatgatggac caggagcgac cacaacaccg cagcttctgc gaatcttaaa
    91081 agaaaaaaac gtgcatgcca cttttttcgt cttaggagaa aatacggcgc agcatcctga
    91141 aatcgtgaag cagacagctg aagcagggca cgagattggc aatcacacat acgatcatca
    91201 gaatctggcc actctttctg cccagtcgat gacggaggaa gtgacgaaag cagacactga
    91261 gatcaaaaaa gtcactggca aaacccccac ttttgttcgt ccgccctatg gttctgtcac
    91321 gaatgtagga gcaacgatca tccagcgacc gatcatcgaa tggtctgttg attcagaaga
    91381 ttggaagaca agaaatcctg atttgatttt gcagaagatc caagcaacag tatacgatgg
    91441 ggcaattatt ttattccatg atatctatcc tgaaacgatt cgtgccgttc ctcaagtgat
    91501 cgattatctg aaagagcaag ggtatcgcat cacgacagtt ggggatttat tagggcatcc
    91561 aacggctgtc gagaactatt atggcagaaa cgatcatcgg ccagttcagt aagtgagaca
    91621 agtatcttta ataaataaca cattttaata agtagttgaa cacataacta ccttacttgc
    91681 aaaggcttaa caatatctat acaggtacaa caaaaaactg tccaccaatt ttctttggcg
    91741 gacagttttc acttaaaaat aaagaagcaa ctattcgtaa attatgctaa aatagcagta
    91801 gaacgcgtcc tgagggaatc gaacccccgt ctcaagaacc ggaatcttac gtgatatcca
    91861 ctacactaag gacgcaagca ctgggataat tgtaactaaa cagataaaaa attacaaggg
    91921 gattggacaa aaaaatgaaa tttgagcaaa atttttcaca aaaacagcag cagacacaga
    91981 aactagccat gacgcaacag ttgcaacagt ccatccaagt tttacaatat aacagtgagg
    92041 agctgttggc attcgttgag aatcaagcaa tggaaaatcc attggtggaa gttgttgagc
    92101 cggaatggca gccagattac ataaaagctt cttcatcttc ttatgaagga gaagagacaa
    92161 attacctaaa tcagattcct gatacaaaag ggtctttatt tgattcattg atcgaacaag
    92221 tccatttgaa ttaccgagat acttttttga ggaaaatcgt tctttatctt gtagaataca
    92281 tcgatttgaa cggatttttg acgattagtt tagaagaagc cggaaaagag attggagcta
    92341 cgcctatcca aatgctcgat gcgttgactc tgattcagca attagaacca gctggagtag
    92401 gtgcacgtag tttgcaagaa tgtctcatgc ttcaaacaga acgagatgat tatgcgccgg
    92461 aattagctta tatcgtgttg gaagaatgtt ttgaggaact ggtggagcga aaatggaaag
    92521 aaatcgcaca acgtttttct gttgatctac atgctgttca gcagatattc gactatttac
    92581 aaacgttgag tccaagccct ggccggattt tcgaccgtag cagcgaattg tacattattc
    92641 ctgatgtccg ggtattagtg gacgacgata aaaatgtaca agttatctca aaccgaaaaa
    92701 atcagccaaa tatacgcttt caagagagtt acttcaaaca aatgtcacaa caagcagata
    92761 aagaaactga aaattattta aaagaacgga aacaggaatt cgaatggttg aagaaaacga
    92821 tcctacaacg tggggataca attttgcggg ttgctcaagt cattgtttcc cggcaaaaag
    92881 ctttctttat cgacaaggaa cgtccaatca agcctcttac gttaaaggaa gttgcaactg
    92941 agatagatgt gcatgaatcc acggtcagtc gtgcagtcaa cgggaaatat ttggaaacag
    93001 acttcggtgt atttgaatta aaaaaatttt tcactacacg aattcctacg aatagtacag
    93061 aacagacaga agacctttca gcagatacag cgaagaaaaa gctgcaggaa ttagtcgatc
    93121 aagaagacaa aaacaagccg ttgtctgacc agaaattggt tgaattgctg aaaaaagatg
    93181 agatagcgat ctcaagacga acagtagcaa aatatcgtga tttattagga atcccgagtt
    93241 catcaaaaag aaaacgttat gataactaat cagtcaaaag actagaaaaa gtatttcact
    93301 ttttctagtc tttttagttg aaaaacgaga gcaaaactgt tagacttaca gtcgtgaggt
    93361 tgagatttcc ctttattgat gtgaaattcg aatagttaat ttcttttttt atcgtatatg
    93421 ggtcgtttta agtctacatt ggacgtaaag tgtccaacta aggagatcgc tatgctggat
    93481 gaaataaaaa tgattgaatc tgttgcacca gatattatcg aagtgttgca agaacgctat
    93541 aaaattttac gaaatatcta ttggatgcag ccgattggac gtcgaagttt atcggaaagt
    93601 atggggatca cagaacgagt attgcgaaca gaaacagatc ttttgaaaaa tctgaatttg
    93661 atcgacacct caaaaagcgg tatgacgctg acaactaagg gcgaagaagt ttatcaaagc
    93721 cttgaaaact tcatggatca gcttttaggt acgcatcaaa ccgaacaaca gttggcagaa
    93781 tattttggta accaacgctg tatcgttgtt tcaggaaaca gcgaagagca gaccaaagtg
    93841 gctgatgcat tcggcgaagc gctgagcgaa gccctagacc gactacttcc agaaggcgag
    93901 aatatcatcg ctgtgatggg aggaactact atggctgtgg tagccgaaca attgtctaat
    93961 ctggaaaata agaaacggca taacctgttt gtccctgcaa gaggcgggat tggtgaagcg
    94021 ataactgtac aggcaaattc tgtcagtgca agaatggctg ctaaagcaaa cggtaaccac
    94081 cgtgcacttt atgttccgga acaattaagt ctggcaactt acaattcttt actcaatgag
    94141 ccatctatcc aagaagtctt aaacttgatt agtgaagcga attgtgttat tcatagtatt
    94201 gggcgtgcat tacacatggc agcacgtcgt aagatgactg aaaaagaatt agtcatgctg
    94261 aaacaagcaa atgctgttgc ggaatctttt ggctactttt tcaatgaaaa aggtgaagtc
    94321 gtttataagg tccctagaat cggcatagaa ttgcaagatt tggaaaaagt cccgatcatc
    94381 atggcaatcg cgggcggaaa atcaaaagct aaagcaattc gagcttatat gaaaaatgca
    94441 ccaaaacaaa cgtggctcat cactgatgaa gctgctgcaa atgagatttt aaaaggggta
    94501 accctttaaa ataaatattt ttttgatttt cataaggagg aaatcttaaa tgacagttaa
    94561 agtaggtatt aatggttttg gacgtattgg acgtctagca ttccgtcgta tccaagatgt
    94621 agatggaatc gaagtagtag caatcaacga cttgacagat gctaaaatgt tggcacactt
    94681 gttaaaatac gacacaactc aaggacgttt caacggaaca gttgaagttc atgaaggttc
    94741 attcaacgta aacggaaaag aagttaaagt attagctaac cgcaacccag aagaattacc
    94801 atggggcgaa ctaggcgtag atatcgttct agaatgtact ggtttcttca cttctaaatc
    94861 agcagctgaa aaacatttaa cagctggtgc taaacgcgtt gttatctctg ctcctggcgg
    94921 aaacgatgtt ccaacaatcg tttataacac aaaccacgaa acattaactg gtaaagaaac
    94981 agttatctca ggtgcttcat gtactactaa ctgtttagct cctatggcta aaacattgaa
    95041 cgacaaattt ggtgttgttg aaggattaat gacaactatc cacgcttaca caggtgacca
    95101 aatgactcta gacggacctc atcctaaagg tgacttccgc cgtgcacgcg ctgctgctgc
    95161 aaacatcgtt cctaactcaa caggtgctgc taaagctatc ggtttagtaa ttcctgaatt
    95221 gaacggtaaa ttagacggag ctgctcaacg tgttcctgta ccaacaggtt cattaacaga
    95281 attagtaaca gttcttgaaa aagaagtaac tgttgacgaa atcaatgcag caatgaaaga
    95341 agcttcaaac gaatcttacg gatacaacac agacgaaatc gtttcttcag atatcgttgg
    95401 tatgacttac ggttcattat ttgatgctac acaaactaaa gtaatgacag ttggcgacaa
    95461 acaattagtt aaaactgttg cttggtacga caacgaaatg tcatacactg cacaattagt
    95521 acgtacttta gaatacttcg ctaacttata agatagacaa acgtacaagt gtaaattata
    95581 gacatgtaca tttaaaagcg gggaagcaat cgcgcttctt ccgctttttt tgataataag
    95641 tttattcagg aggaaataaa atggctaaga aaacagtgaa agatatcgat ttaaaagaca
    95701 aaaaagttct tgtccgtgtt gacttcaacg ttcctttgaa agacggcgtg atcactgacg
    95761 acactcgtat caaagcagca ttgccaacaa tcaactacgt tctagaacaa ggcggaaaag
    95821 caatcctttt ctctcacctt ggacgtgtaa aaacagaaga agataaagaa ggaaaatctt
    95881 tagctccagt tgcaaaacgt ctaggcgaat tattaggtaa agaagtaaca ttcgtacctg
    95941 aaactcgcgg agaacaatta gaagaagcaa tccgcaacat gaatgacggc gacgttgtcg
    96001 tattcgaaaa tacacgattt gaagatattg acggtaaaaa agaaagcaaa aatgatacag
    96061 aactaggtaa atactgggct tcattaggcg atgtatttgt taacgatgct ttcggtacag
    96121 ctcaccgtgc acatgcttct aacgtaggta tcgcttcaac tggtatccca acagttgctg
    96181 gattcttgat ggaaaaagaa atcaagttca tcggtgaagc agtagaagaa ccaaaacgac
    96241 caatgattgc aatccttggt ggcgcaaaag tttctgataa aatcggcgta atcgaaaact
    96301 tgattcctaa agcagataaa atcttgatcg gtggcggaat gacttacaca ttctacgaag
    96361 caaaaggaat caagatcggt aactctctag tagaagctga taaagtggaa ctagcaaaag
    96421 aattaatcga aaaagcaggc gacaaacttg tcttgccaat cgacaatgtc tgtgcaccag
    96481 aattttcaaa tgatgttgaa acacaagtaa tcgaaggaga cattcctgat ggtttgatgg
    96541 ctttagacat cggcccagca tcagtaaaat tatttgctga tacattacaa ggtgcaaaaa
    96601 cagttgtttg gaacggacct atgggtgtat ttgaaatgag taactttgct aaaggtacaa
    96661 tcggtgtttg tgaagcaatc gctaacttag aaggcgcaac aacaatcatc ggtggcggag
    96721 actcagccgc agcagcagaa caattaggat ttgctgacaa attcacacac atctcaacag
    96781 gtggcggcgc aagcttggaa ttgcttgaaa gtaaagaatt accaggacta gcagcaatca
    96841 acgataaata aacgaccaag tttgctcaat tctgacgagt aatcgaacaa aaggtgaagg
    96901 gagttttcat gactccctag ccatttttca ataaattaag gagtgtgttc ctcaatgcgt
    96961 aaacctatta tcgcaggtaa ctggaaaatg aacaaaactg catcagaagc aaaagaattt
    97021 gctgaagcag taaaaaacaa aatcccttca aatgacaaag ttgattcagt catcggatct
    97081 cctgcattat tcttacaaga attaatgaca tcagctgaag gtacagaact aaaaatctca
    97141 gcacaaaact gctactggga aaactcaggt gcgttcactg gtgaaacttc accagcagct
    97201 cttgctgatc taggtgttca ttatgtgatc atcggacatt cagaacgtcg tgaatatttc
    97261 catgaaacag acgaagacat caataaaaaa gcgaaagcta tctttgcaaa tggtatgaca
    97321 ccaatcctat gctgtggcga atctttagaa acctatgaag caggcaaaac tgctgaatgg
    97381 atcgaaggac aaattacagc tggtttagct gatctttcag ctgaacaggt gtcaaacatg
    97441 gttattgctt atgaaccaat ctgggcaatc ggtactggta aatcagctga cgcacaaatc
    97501 gctgacgaaa tttgtggagt tgtacgtcaa acagttgaaa aactttatgg aaaagaagta
    97561 tcagaagcag ttcgtatcca atacggcggt tctgtaaaac cagaaaatat tgctgaatac
    97621 atggcaaaag aaaatgttga cggtgcttta gtcggtggcg caagcttgca agcagattca
    97681 ttcttgtcat tgttagacgc tgtaaaataa ttgttgaaaa tttgcgaaaa atgcaagaaa
    97741 tgtttgcact aatgagcaaa attaactaaa atcgtatatg agggaaatcc cttaggaaaa
    97801 aacaaactca aaggagagac aaaacatgtc aattattact gatgtttacg ctcgcgagat
    97861 cttagactca cgtggtaacc caacaatcga agtagaagta tacacagaaa gcggagcttt
    97921 tggccgcgga atggttcctt caggtgcttc aactggtgaa tacgaagcag ttgaattacg
    97981 tgacggagac aaagctcgtt atggcggtaa aggtgtaact aaagctgtcg acaacgtaaa
    98041 caacatcatt gctgaagcaa tcattggcta cgatgttcgt gaccaaatgg ctatcgacaa
    98101 agctatgatc gctttagacg gaactcctaa caaaggtaaa ttaggtgcga acgctatttt
    98161 aggtgtttct atcgctgttg cacgtgcagc tgctgactac ctagaagtac ctttatacca
    98221 ctacctaggc ggattcaaca caaaagtatt gccaacacca atgatgaaca tcatcaacgg
    98281 cggatcacat gctgataact caatcgactt ccaagaattc atgatcatgc ctgttggcgc
    98341 tccaacattc aaagaagctc tacgtatggg tgctgaagta ttccacgcat tagcttcaat
    98401 cttgaaagct cgcggattag caacttctgt tggtgacgaa ggtggatttg ctccaaacct
    98461 tggttcaaac gaagaaggtt ttgaagtaat catcgaagca atcgaaaaag ctggctatgt
    98521 acctggtaaa gacgttgttc ttgctatgga tgctgcttct tcagaattct acgacaaaga
    98581 aaaaggtgtt tacgtactag ctgattcagg cgaaggcgaa aaaacaactg acgaaatgat
    98641 caaattctac gaagaattag tttctaaata tccaatcatc tcaatcgaag acggattaga
    98701 cgaaaacgac tgggacggat tcaagaaatt aactgacgta ttaggcgaca aagttcaatt
    98761 agttggtgac gacttgttcg taacaaacac tcaaaaatta tctgaaggta tcgaaaaagg
    98821 aattgctaac tcaatcctta tcaaagtgaa ccaaatcggt acattaacag aaactttcga
    98881 agctatcgaa atggctaaag aagctggcta cacagcagtt gtatctcacc gttctggtga
    98941 aacagaagat tcaacaatct ctgatatcgc tgttgcaaca aacgctggcc aaatcaaaac
    99001 tggttctcta tcacgtactg accgtattgc taaatacaac caattactac gtatcgaaga
    99061 ccaacttggt gaagttgcag aatacaaagg tttgaaatct ttctacaact taaaaaacaa
    99121 ataattcttt tctaatgaag atacatgatc gactattgaa agatagtcga gtatgatcac
    99181 ttagttaagt aatcgaactc tctacttgct gaaatatcag caggtagaga gtttttttgc
    99241 aactagcttc tgtatatgat gtttacaaag aatggtacaa gaaaagatca tccttgaaaa
    99301 agggctcttt gtcaataagg actgatgagt tgtgcaaaat caaatctgag ccagaatgtg
    99361 gttcattctg actcagattt gattttgcac aactcatcag tccttattga caaagagcct
    99421 tattttgcta atccagctct gtttattcag cctatttttc tttttgaata tatcaagcgt
    99481 tgtggcaaca tagtgatgac taatgaaaca acgacgatag acaacaaacg atcaaggtag
    99541 tctgtacctg cctgtaccaa gatcacactt gttgtctgac ttaaacctaa cccatgtaat
    99601 agctgaacga tcatactgga tcctgaggag gtgatcccgc caaataactg aacggtaatg
    99661 atcgaagaaa cgatcgttcc aggtaccgac aaaatcaaag cgagtaataa cagtttcaag
    99721 ctgtttttat ctttgccgag atatcttggc aaaatcaatc cagcaagcaa gcctgtgaga
    99781 atttggattg gcgaataata cagagaaaaa atatctgtag tcactccact taaaataccg
    99841 ctggacaatc ctgtcagcat tccaggtaca ggcccaagca atgcaccagc aaaaatcgtt
    99901 ccgatagaat cgagatagat tggcaaacga agccataaag caatcgttcc tccaatataa
    99961 ttgatcccaa tacacaaagc catcactgta agtacgcgag ttgccatttt gtttttattc
   100021 attttgttag cccatcttta acctttccaa atctttcata atcgtttctt cttgtgcatt
   100081 taaaagaacg gttaaaaact ttcggaaaaa aagacgagta tctacttttg tcataatttt
   100141 actgttagca ggtttctgcc aaaattcata acgatcaacc aatgtttgtc cacgacttat
   100201 tccttgagtt tccacagcag tgaagctttt gaaaccttca cagatggcct cctcgataaa
   100261 ataagcaaca gctaacggat cattgatgac acatcctaaa attctttctt gtttccagtg
   100321 gaagtcaaaa taaaaacgag tgatcgcttt tagatactct ccctcttcag gattcatttg
   100381 acagcagtat tcgaggatag tcggtgtcaa gacgatttct cttgtcacat ctaacccaac
   100441 catttctatc gtttgtttga gattctcgaa tacataagaa gctgcttcag gatcacacca
   100501 gtaattgtat tcagcaactg gcgaacagtt accatggctt ttgtaagttc cacccatcga
   100561 gacaaaacgt tccatatgtt tcccaatatt tgggttgact ttcaaagcag aagcgatatt
   100621 ggtcaaagga cccaaagcaa tgactgatgt atttgtcttt tctttgaaat aatcagccaa
   100681 aaaatcaacg gcatggagag gttctgcctg ttttctcaag atcatcggga aatttgtttc
   100741 ccctaaacca tccataccat gagtgtcttg tgcactgatg aaaggttgct tcaaaggttt
   100801 ttccattcct tgataaacag gaatgtctaa acgatcacag cgttccaggc atttcagcac
   100861 attctgcgta cctatatctg cagggacatt cccacaaact acggtaatag caactacttc
   100921 gatatcaggg gatttgacag ctaatgataa agctaaagtg tcgtcgatcc ctggatcgca
   100981 atcaataatt acttttcgca ttatttccaa tctcctttct ttagagatac ttagtttttt
   101041 attctgggaa gtttccgaac cagtccaaga cgagcgtctt gattataatg cacgaaatta
   101101 gtatactggc ttttattgcg aatgtaaatg ctctcttaca agtaaatcta ttgaggagaa
   101161 ctttaagtaa atgatacaat gaaaaagaaa tggaatttac gtgtgccgaa aataaagaat
   101221 cctatggatc ggtacattgg ataatagata gattatagtt tggcagaaag cggcgggtgt
   101281 acaatggtta ttttttattt cattcttatt ctgataatta tagggatcag ttaccatttt
   101341 ctttcttatt tttatgcaaa gaaattagta agagcgggag tacagagagg atatgactgg
   101401 tatgaagaca ctggtcatcg tttgatggac cctgctgcag tcacgtcagt agaaaaaaaa
   101461 cgacaaaaat tagaagaaga gtgtgaaagc ttttgggagc agggaacacc caaaacaatc
   101521 aaaagttatg acgggttgaa actagctggt cagatgttca tccatccaaa taagcagaat
   101581 aaatgggtca tttgcgtaca tgattaccga agcacaggga aaagagacat gtctcatata
   101641 ggtaaaagat atgcagagaa aggattcaac gttcttgtac ctgatttacg tgcgcacgga
   101701 gaaagtgaag gagaaatcat cggaatggga tggctagatc ggctagattt aattgcctgg
   101761 atccaactca tcttagatga acagccgaat gcgtccatta ttttacacgg cggatcaatg
   101821 ggagcttcta cgatcatgat ggcaagtggt gaaaaacttc catcagcggt caaaggattt
   101881 attttagaca gcggatatgt ttctgtttat gcagaattcc gatatatgtt aagtaaaatc
   101941 actgtctttc ctaaaaaaat ggtcatgaga tatgcgaatc attatgccca gaaatacgcc
   102001 ggttactcct taaagcaagc atcagctacg agacagcttg gcagcaatca tctgccttta
   102061 ttagtcatcc atggtgaaag agatcatttt gtccctacag aagcagcgta cacgattcaa
   102121 aatgctacgg caggggataa agcactgctg cttgttccgg aagcagaaca cttggaagca
   102181 tcgatgaaag atccgaaaac ctattggaca gtgatttttt catttattga acaaagaata
   102241 acgatgaatt aattttctct tcttttttgt aagtaattcg aggataaata attgtttata
   102301 gatcaggaga ctgctaaaat aaggtaggaa taaaaaaata tcagttattt gaggagtgcg
   102361 gcatatggaa atcaaagaag aaaaaatcgt cttgctttat tcaatgatga acaacaagag
   102421 atcggagaaa tgacatggtc agatgcgggc ccagacatca tgatcgttga ccatacattt
   102481 gtagatccag catatcgtgg tcaaaagtta gctgaaaagc tagtgtatac tggagtagaa
   102541 ttagcaagac gagacgggaa aaagatcatt cctttatgcc cttatgcaaa aaaagagttt
   102601 gaaaagaaac cagaatatca agacgtctta cgtcagtcat aagaataaca gctgaaagtt
   102661 ttgaactttc agctgttatt ccatttatat agagttgtca cggactttta tctatgataa
   102721 agttaaagag acgatatctt ttgggaagga ggctgcgata tgtataattt aattttggga
   102781 atcgtgatcg ttttatcgat tgttatggtc attgcgatta tgatgcagcc aagcaagcaa
   102841 aatagtgcag cgagtgcatt taccggcggt gcggatcaac tattcggcaa acaaaaagct
   102901 cgcggctttg aagctgtcat gcagcgatca actgcagtta tgggagctat ctggatgatc
   102961 ttattatttg tcctagcata tttatcttcg aagtagttga ataagcctct cgcaaaacgg
   103021 cgggcggctt tttttattgc aaagagaacg cttaagaaga agttatgaaa gaaactatgg
   103081 taaaatgagg cgaaagaggt gagacgagtg agacaattac caaaacccct ttatgcaaaa
   103141 catggaaagc gagcggtttt gctgcttcac gcttactcag gaagtccaaa cgatgttcga
   103201 atgctcgcac gatttttgga aaaagcagat tatacagttt atgcgccgct ttttaaagga
   103261 cacggaacaa tggagccata tgatatcttg caagaaaaag cagaaagctg gtgggcagac
   103321 actaaaaaag ccatccattt tttacagtct gagcagtttt ctgatattgc cgtattagga
   103381 ttatcaatgg gcggcatctt tgctgtacga gcactagaag aagaatcagt gattggcggc
   103441 ggttttttct gttcgccttt gtctcctgta aaaacaaacg tgcctgaaaa ctttgaaaaa
   103501 tacgtacgtc aagtgctgaa gacagcaggt aaatcagaga aagaaatcaa tgaaaaagca
   103561 gttgcttacc gctcgttagc tgaacaacaa ttaatggata tacaagatca ggcagcaatc
   103621 gtagaaagta ggttgtcaga tatccaacag ccgatatttt tagctcaagc tgggaaagat
   103681 gaaatgatcg accctaatgg cgtatttgaa actgcacgca agttgagccg tcagcgagtg
   103741 acacttcaat ggtatcctga aagtggtcat gtgattacag ttggtacagc aagacgcgaa
   103801 ttagaaaaag acgtcttgga atttttagaa aaattacctt ggaatgagga ataaatatga
   103861 caaaagaaac gataaaagag aaaattctct ttttcatgga aagcagtcgc aaacgcagtt
   103921 tttctatgga agaaatcgct gaaggtttag ggttccaaaa aagcgatgat tttaaattac
   103981 tagtacaaac gattgctcaa atggaaagag aacagagtat agttttcaat aaaaaaggaa
   104041 aagtgaaact tcctttaaaa ccaatcctga tcgaaggaac atttcgagca aatgaacgag
   104101 gatttggatt tgtaacgatt gatcccgaag aagatgacat ctatatccca aaagaagcga
   104161 ctggttttgc aatggatgga gacaccgtag caatcgatat catgaagcga gcaaatacag
   104221 atatggatcg cggagcagag gggaaagtag tcgagattcg agaccgggcg actactcagt
   104281 tagcagggga attcgttgct tattcagaag aagaaataca agaaacagat ctttacggcg
   104341 ttgttatccc gaaagataga aagctcaacc aatttaaagt atatgcagca gcagagggag
   104401 ttcgtccagt tgacggaagt attgtgctga tcgaactgac ccattaccct gaaaaagggt
   104461 atgcgactag tttagaaggg ataatcaagc aagtgattgg tcataagaat gaccctggca
   104521 tggatatcct ctcaattgtc gtggctaatg gtatccctac gaaatttcct gatgatgtat
   104581 tgtctgaagc agatgaagtt ccagatcaaa tcagcgaaaa ggatataact ggacgtagag
   104641 atttaagaaa tcagctcatt gttacgattg atggagaaga tgcaaaagat ctagatgatg
   104701 cagttacggt taaaaaatta gataacggta attattttct tggagtacac attgcagatg
   104761 tttcttacta tgtgacacaa ggcagtcaat tggacagaga agcatatgaa agagggacaa
   104821 gtgtatattt gactgatcga gtaattccga tgatcccgca acgtttatcg aatggtatct
   104881 gttcactgaa tccccatgtt ccaaggctga ccatgagttg cgaaatggag attgatccaa
   104941 atggacaagt agtctctcat gatattttcc caagtgtgat ccaaacaaca gaacggatga
   105001 cctacacagc tgtcaatcaa atcttagaag atcaagacga agaaacgatg caacgctatg
   105061 ctcagctcgt acctatgttc caagaaatgg gtgaattgca ccgaatcctt gaaacgatgc
   105121 gaatcaaacg tggcgcgatt tcttttgagg atcgcgaagc gaaaatcctt gttgatgctg
   105181 aaggacaccc aaatgacatc cagctaagaa gcagaggaat tggtgaacgc ttgatcgaat
   105241 ctttcatgct tgcggccaat gaaacggtag ctgaacatta taataaatta aatctgccgt
   105301 ttatttaccg aatccatgaa cagccaaaag aagaaaaaat gcagcgcttc tttgattttg
   105361 cttcagcttt gggcattctg gtccgaggaa cgaaaggaac gatcacacca aaagatttac
   105421 agcatgtgat cgaaggagta gaagacaaac cagaagctgc agttatcaat actatgttgc
   105481 taagaagcat gcaacaagca cgctattcag aagacaattt tgggcattat ggcttagcgg
   105541 cagattacta cacacacttt acatctccta ttcgacgcta tcccgatcta atcgtccatc
   105601 gtctgatccg ttcttacagt gaagataaaa gtgaaagcaa tcaaagttcg tgggctgcgg
   105661 aacttcctga aattgcagat catagttcta agatggaacg tcgtgcagta gaaacagaac
   105721 gtgaagtaga ttccatgaag aaagcagaat tcatgatgga caaagtggga gaagaattcg
   105781 atgggatcat cagctctgtt gtgaaattcg gcctgtttat cgaactgccg aatacagtag
   105841 agggattgat ccatatcaat gaattgaaac aggactactt ccattttgtt gaaaatcatt
   105901 tagctcttgt aggtgaaaga actggtctga cttttaaaat cggacagaaa gtgcgagtaa
   105961 aagtagtcaa agctgatcca gatgaacgag cagtagattt tgaacttgtt tccgcagaag
   106021 aggttacagc gttggaacgg ccaaaaacac gaaatggaaa atcaggaaaa cgcgaaggaa
   106081 aacaagcagg aaaacgccca gaaagaaatg gcaagaagaa caaacgatat agcgatagta
   106141 agcaaacgtt cggtaagaaa aaagggaaga agccatttta caaaggtgtt aaaaagaaga
   106201 aaaagaaaaa ataaaatgag ttggaggaaa cagctatgcc aaaaggcgag ggaaaattaa
   106261 ttgcacaaaa caagaaagct cgccatgatt attcgatcat cgacacgatg gaagcaggga
   106321 tggtcttgca aggaaccgag atcaagtcga tacgaaacag ccggatcaat ctaaaagatg
   106381 gatttattcg cgtccgcaac ggagaagctt tcttgcataa tgttcatatc agtccttatg
   106441 aacaaggaaa tatttttaat catgatccgt tgcgcacgag aaagttatta ttacacaaaa
   106501 aacaaatcat ccggcttgaa aatgaattga aaaatactgg aatcactgtt gttcctttaa
   106561 aagtctatat tcgtaacggc tatgccaagg tattgattgg tctggcgaaa gggaaaaaat
   106621 cttatgataa acgggaagat ttgaaacgaa aagatatcga tcgacaaatt gatcgaacat
   106681 taaaaaattt ctctagataa tttcattatc ctttttcgca tattcggtgc ttttgctttt
   106741 acttaatgat aaaatttgtt agcatttaat ctgataaaac atgattatca taggtttttt
   106801 cttagatcag gagcaccgtg tataaagaaa aattcgcttc gtttttgact gaaataaaaa
   106861 agtgtctaat tttcatgaaa atgttttgaa ttttctgttt catggtggta tgataccgtg
   106921 tggttagaaa ccgattggaa aaaaccagat acgcacatga attgatttta tgtgaatttc
   106981 ggggaaaaga ggtgaaatgg attggatgaa cgctcgctaa cgttccacat tggaccaatt
   107041 tggtttgatg gtacagtttg tataatggtg ttactgacct gtttgattgt tttcttctta
   107101 gcttactttt ttacaagaaa tcttaagttg aaaccaacag gcaaacaaaa tgcgatagaa
   107161 tgggtcattg attttagtcg aggaatcgta acagataatc tgcctagaaa agaattgagc
   107221 aatttccatt tgttggcatt tacattgttt ttatttgttt ttgttgcaaa caacatcggt
   107281 ttagtaacaa aaatcgtttt acctaacgaa acaacacttt ggaaaagccc gacagcagac
   107341 ccgtttgtta ctttaacttt ggcatttata atgatcttac ttactcactt attcggggtg
   107401 aaaaagttag gcttcaaagg atatttcgta aattcgttct tgaaacccta tagttttatg
   107461 tttccgatga aactgattga agaatttaca aacttattaa cacttgcttt acgtctttat
   107521 gggaatattt atgcggggga agttttgcta accttgattg caaaaatgat gacaagctta
   107581 ggctggttct cattaccatt agcaattcca ttagagatgg tctggatcgc gttctccttg
   107641 tttattggga gcatccaagc atttgtcttt gtcactttgt caatggttta tatgagccat
   107701 aagattgaag tagaagaata atactcggtt aaaaaacaaa ctactattta tctattttag
   107761 gaggaaaaca attatgaatt atatcgcagc agcaatcgca atcatgggag cagcaatcgg
   107821 agccggttat ggtaacggtc aagttatctc taaaacaatc gaatcaatgg ctcgccaacc
   107881 tgaaatgtct ggtcaattcc gtacaacaat gtttatcggg gtagctctag ttgaagctgt
   107941 tcctatctta ggggtagtta tcgccttgat tctagttttt gccgtttaat tgaatcagta
   108001 ttaaggcaga aacaacatcg tttgttactg cttttttaca tggaaactag aaatactcca
   108061 aagaaaggaa ggctcgccta tgctgaatca attggcaatt gcagaagttg gcaatgcgat
   108121 gttaggtaat atcatcgttg tcagcggctc atttttgata ctactggctc tcttgaagca
   108181 ctttgcttgg ggaccaatca gcgatatttt gaaaaaacgt gaagacaaga tcgccaatga
   108241 tttagattct gcagaacaat ctcgcatcaa ctcagcgaaa atggaacaag aacgcgaaca
   108301 acaattgtta gcctctcgtt ctgatgcagc tgatatcatc aaaaatgcga aagaaagtgg
   108361 agaattaagc cgccaaaata ttttgaagga tgctcaagaa gaagcagctc gtctaaaaag
   108421 caaagcccaa gctgatatca ctgtagaacg tgattcagcg ctgaactctg taaaagacga
   108481 cgttgcagaa ctctctcttc aaatcgcgga aaaaatcttg aacaaagaat tatctccaga
   108541 aatgcatgaa tcattaatca atcaatacat tgaaggtcta ggttcttcaa atgaaactag
   108601 ataaatatac agtaggaaga cgttacggga aagctttatt tgaactggcg atcgattcaa
   108661 atcaagcaga agaaatctat caagatctcg taagtttacg tcaaatctat gaacaagtac
   108721 ctggattagg gaatatgtta agtgatgttc gtctagaacc tcatgaaaaa cgagaaatca
   108781 tggacaagct tgtcagcggt tatgatggga tcgttaaaaa ctttttagaa gttgtttatg
   108841 agtataaccg aatggatgac cttttgttca tgatcgaaga atatgaacgt cgatatgatg
   108901 aacatcaagg gttactattg ggaagtgtca caacagcagt cccactttca gacgaacaac
   108961 gaatacaatt agaaaagaat gttgcaaaaa caatggacta tcaatcagtt gaattaaaac
   109021 aaatcgttga ttcttctatt attggtggcg cgattgttga agccaaccat cgagtaatcg
   109081 acggaagcat tcgcacgcaa ttagaaaaaa tgcgtaatca attaaacaga tagtacaaag
   109141 aggtaggtga atcgaatggc catcaaagca gaagaaatta gtgccttgat taaagaacaa
   109201 attgaaaatt atcaaaacgt gctttcagtc gaagaaatcg gtaccgtaac ttatgtaggt
   109261 gacgggatcg ctcgtgcaca tggtttagaa aacgcgatga gtggtgagtt gcttgaattt
   109321 tcaaacggct catacggaat ggcgcaaaac ttagagtcaa atgatgtagg tatcattatc
   109381 cttggcgatt tcgagtccat tcgtgaagga gataaagtaa aacgaacagg taagatcatg
   109441 gaagttccag ttggagaggc cttgatcggt cgggtagtca atccgctagg tcaaccaatc
   109501 gacggactag gtgaaatcgt tactgacaaa gctcgtccag tagaagcgat ggcaccaggt
   109561 gttatgcaac gtaaatctgt taacgaacca atgcaaacag ggctaaaagc gatcgacgcc
   109621 cttgtgccaa tcggacgcgg acaacgtgaa ttagtcatcg gtgaccgtaa aacagggaaa
   109681 acttctattg cgatcgatac gatcatcaac caaaaaggtc aagatatgat ctgtatctat
   109741 gtagcaatcg gacaaaaaga ttctacagtt cgtacacaag ttgaaacatt gaaaaaatat
   109801 ggcgcaatgg attacacaat cgttgtgaat gccggtgcgt ctcaaccagc accattgctt
   109861 tatatcgcac catatgctgg tactgcaatg ggtgaagaat tcatgtacaa cggtaaacat
   109921 gtattgatca tttttgatga tctttcaaaa caagctgttg cttatcgtga actttccttg
   109981 ctacttcgcc gtccaccagg tcgtgaagct tatcctgggg atgttttcta cttgcactca
   110041 cgtttattag aacgtgcagc aaaattaagt gatgatttag gtggcggttc aatgactgcc
   110101 ttaccatttg ttgaaacaca agctggagat atctctgctt atatcccaac aaacgttatt
   110161 tcgatcactg atggacaaat cttcttagaa agcgacttgt tctacgcagg tactcgtcca
   110221 gcggttgatg ccggactatc tgtatctcgt gtaggaggtt ctgcgcaaat caaagcaatg
   110281 aaaaaagttg ctgggacttt acgcctagac ttagcaagtt accgtgaatt agaagcattt
   110341 acacaattcg gttctgactt ggatgcagca acacaagcaa aactaaatcg tggacgccgt
   110401 acagtagaaa tcttgaaaca aaaattgcat gcaccgctag ctgttgaaaa acaagtagtg
   110461 attttgtatg ctttgacaca tggattctta gatagtatcc ctgtagacag tattttagac
   110521 ttcgaacatg aattattcga atatctggat accaatcatt cagatatctt tgaaacaatc
   110581 cgtacaacaa aagatcttcc agaagaagaa gcgttgaaca gtgcgattca ggaatataaa
   110641 gacatgttct tagctacaaa aggaagtaat tcctctacag aagataaatt gaaatccatt
   110701 caaaatgcat agtgaggtga gatgaatggg tgcttcatta aatgaaatca agacacgtat
   110761 cgcttcaacg aaaaaaacga gccaaatcac gcgggcaatg cagatggtgt ctgcttctaa
   110821 gttgacaaaa tctgaagctt cttcacagaa gtttcaggtt tatgcaacaa aagtaagaga
   110881 aatcgttacg catttgactg ctactcagtt aaatgatatt gcctcagaaa atcctagagg
   110941 ggatatcaat tacaacagca tgctgctcag ccgtcctgtg aagaaaactg gttatatcgt
   111001 catcactgca gatggcggtt tagtcggtgg atataacagc tcgatattga aacaaacgat
   111061 gtctatttta gaagaagacc accaatcacc cgatgattac gtgatgatcg caattggcgg
   111121 aactggtgca gacttcttta aagcacgcgg tatcaatcta gcatatgagc tgcgcaatct
   111181 atctgatcag ccaagctttg atgaagtccg caaaattgta aatatggcaa caactatgtt
   111241 ccaaaacgaa gtattcgatg aattatacgt atgttataac catcatatca attcgctaac
   111301 tagtcagttt cgtgtagaaa aaatgctgcc aatctcagac ttagatccag aagaagcaac
   111361 gactttcgaa caagaatata tttttgaacc ttcaaaagaa gaaatcttgt ctcagttatt
   111421 gcctcagtat gctgaaagtt tgatctacgg tgcgatcgtt gacgccaaaa cagcagaaca
   111481 tgctgctggt atgacagcaa tgaaaacagc aactgataat gctgctaata tcattgatga
   111541 gctgacggtt tcttataacc gtgcaagaca aggggctatt acccaagaaa ttaccgaaat
   111601 tgttgccgga gcttcggcac tagaatagta ttgagattgg aggaaaaaag atgagttcag
   111661 gcaagattgt tcaagtaatc ggtcccgttg tcgacgtgga attttcttta gaccaatcct
   111721 taccagatat caacaacgca ttagttgttt ataaaaatga cgaaaataaa tcaaaagttg
   111781 ttcttgaagc agcgttagaa ttaggggacg gagtgatccg gaccattgcg atggaatcaa
   111841 cagatggttt acaaagagga atggaagtca ttgatacagg caaagcaatc tctgttcctg
   111901 taggtaaaga aacattaggt cgcgtattca acgtactagg agatacgatc gatttagaaa
   111961 cacctttccc agaagatgcg gaaagaagcg aaattcataa aaaagcacca gcctttgacg
   112021 aattaagtac aagtacagaa attttggaaa cagggatcaa agttatcgat ttgcttgccc
   112081 catatttaaa aggtgggaaa gtcggactat tcggtggtgc cggtgttggt aaaaccgtac
   112141 tgatccaaga actgatccat aatatcgccc aagaacatgg tggtatttct gtatttaccg
   112201 gtgtaggtga acgtactcgt gaaggtaatg acttgtatta tgaaatgaaa gattcaggag
   112261 ttatcgaaaa aacagccatg gtgttcggac aaatgaacga accaccaggt gcacgtatgc
   112321 gtgttgcttt gactggtttg acgattgcgg aatatttccg tgatgtagaa ggtcaagatg
   112381 tactgttgtt tatcgacaac attttccgtt tcactcaagc tggatctgaa gtatcagcct
   112441 tgttaggacg gatgccttct gcggttggtt atcaaccaac attggcaaca gaaatgggtc
   112501 aattgcaaga acgtatcaca tctacgaaaa aaggttcgat cacatcgatc caagcaatct
   112561 atgtgccagc cgatgactac actgacccgg cgccggcaac agcattcgcc catttggatg
   112621 cgacaaccaa cttggaacgt aaattaacag aacaagggat ttatccagcg gtagatccat
   112681 tggcttcttc ttcaagtgct ttagcacctg aaatcgtggg agaagaacat tataaagtag
   112741 caacagaagt ccaacacgta ttgcaacgat atcgtgaatt acaagatatc attgctatct
   112801 taggtatgga tgaattatcc gatcaagaaa aagtgttagt ttctcgtgcc cgcagagtcc
   112861 aattcttctt gtcacaaaac tttaacgtgg ctgaacaatt tactggtctt ccaggttcat
   112921 atgtccctgt agaagaaaca gtgaaaggat tccgcgaaat cttggaaggc aaatacgatg
   112981 atcttcctga agaagctttc cgaagtgttg gccgaatcga agacgtcgta gaaaaagcga
   113041 aaacactagg ctactagaaa ggggtgcccc atggatcaat atttaacagt aaatgtggta
   113101 actcctgccg gtttggtcta tgatcaccat gcagctatcg tcgttgcacg tacgacagct
   113161 ggtgagcttg ggattttgcc taaacatgca ccaatcatcg ttccattgac gattgatgaa
   113221 gttcgtgtaa aacgaacaga ttcagatacc cacgtcgatt ggatcgctgt taatggcgga
   113281 atcatggaag ttcgtgataa tgttgtttca atcgttgctg atagtgcgga acgtgaacgt
   113341 gatatcgatg tatctcgtgc ggaacgtgca aaacaacgcg cagaacgcca aatcgaagaa
   113401 gcaaaagcaa aacaagatac gaacgaattg aaacgggcaa ctgttgcgtt gcaccgagca
   113461 atcaatcgta tcaaagtatc taagcactca taaaatgaga tgcggatgtt tatccgtgtt
   113521 taagaacagt aaaaagaggt tatgacagaa gtggtcagct tcaagacata agaaggaatt
   113581 tacgaaaatt gcttctcaaa tttttgtgaa atctcagctt atttttcgaa gaagctactt
   113641 ctggaacacc gtatatcaga ggttgtgaaa tcagcgtttt gtcctgagta ttagagaaac
   113701 aaatggaaaa tagttcctca tattttgccg ttttttgagc taataccgag ggtcagatga
   113761 ttgaacaccg tttatttgga ataagggact gcgacaagac ttttgtctca gtcccttttt
   113821 ttgcatattt ttagcattta tttcctaaaa aatgtaaggg gattcctata tttttaagta
   113881 tacttgtttt tccttttata cattttatgg tattatcatt ttattagtta ttataaaaca
   113941 atcgttagaa aggacgtcat tatgcaagta tacggaattg atgcggtgct tcgaatcgtg
   114001 agtcatttgg cgtttatcta cttagccttc tggtctttac gttcgttacg cattgaaact
   114061 tttttcagac caatgcataa tacgcaaatt agaatggcaa tcgtactttt ttcaattttt
   114121 ttagggtaca ctgcaagtaa ttttttctta gaggttatcg ctttatgccg aaatcttttc
   114181 gttagcctgt aaattttaaa aaaaggtact attttaaaag caaggatgtt ataatagaaa
   114241 agattttgag taagtgtatg ctcattggaa ttttttggag ggaacaacat ggaagagatc
   114301 atcgtaagag gtggcaatca attaaatgga acagtaagaa ttgaaggagc taaaaatgct
   114361 gttttgccta ttttagctgc tagtttgtta gcagaagaag gtattacgac attagacaac
   114421 gttccgattc tttctgatgt cttcactatg aatcaagtga ttcgtcactt aaacgtagat
   114481 gtagattttg atgaacaaaa gaatcaagta acaatcgacg cttcaagaca attagaaatc
   114541 gaagcgcctt atgagtatgt tagtcaaatg cgtgcttcaa tcgttgtgat gggtccgcta
   114601 cttgccagaa atggacatgc aaaagtagct atgcctggtg gatgtgcgat tggtaaacga
   114661 ccaatcgatt tgcatttaaa aggatttcaa gctttaggag caaaaattat tcaaaaaaac
   114721 ggctatatcg aagcaattgc ggatgaattg atcggtaaca cgatttattt agatttccct
   114781 agtgtaggtg ctactcaaaa tatcatgatg gctgccgtaa aagcaaaagg aacaaccatc
   114841 attgaaaacg tagctcgcga accagaaatc gttgatttag caaacatttt gaataaaatg
   114901 ggcgctcaag tctatggagc tggtactgaa acaatgcgta ttgaaggcgt ggatcattta
   114961 catgcagtca accactcaat cgtacaagat cgtatcgaag caggtacctt tatggttgct
   115021 gctgcaatga cacaaggcaa tgtgctgatt gcagatgcta tctctgaaca taaccgccca
   115081 ttgatttcta aattgatcga aatgggtgca gaaatcattg aagaagaagg cggagtccgt
   115141 gtcatcggac caaaacatat cttacctaca gatgtaaaaa cgatgcctca tcctggtttc
   115201 cctacagata tgcaagctca aatgacagct atccaattag ttgcagaagg tacaagtgtg
   115261 gtgactgaaa cagtgtttga aaatcgtttc caacatttag aagagatgcg ccgtatgaac
   115321 gctcatgtca aaatcgacgg aaatgtagca atcatggatg gaaaccatga attgcaaggt
   115381 gcagaagtat atgcaacaga cttgcgggca gcagcagcat tagttttagc tggcttgaaa
   115441 gcaaatggaa tcacacgtgt gcgtaacttg aattatctag accgtggata ttataatttc
   115501 catatcaaac tacagcaatt aggtgcagac gtcgaacgtg tagacatgga tcaaacttct
   115561 gctgaaaaaa cagcacaaac gattgcttaa ggaagtggct gaatgagtaa ccaacgatat
   115621 atcttattaa ctttgataaa gattttagtg gtgatcttat tgcttatcct tctttttgtg
   115681 gccggaacga tgatcggata tggtgtcatc ggtggcggca atccatttaa agtattccag
   115741 ccaagtttgt ggattcatat tcgagacttt tttcattgat aaataagaat cacagtggtt
   115801 ctagtcgata tgaagtgagc catgaagcag aacatgataa aagaaaacag aagggaacgt
   115861 tgacgttagt cgcgatccct ttttttagta aaagaaaaga aggaatctaa ttgatgaaga
   115921 agatattgat ttatttagtt agaggatatc agcgctttat ttcgcctgca tttccaccta
   115981 gctgccgtta ttacccaacc tgttccaatt atatgataaa agcaattcaa acccatggtg
   116041 cgctaaaagg gacggtaatg gggactgcac ggatcttacg ctgtcatcct tttgtcaaag
   116101 gcggtatcga ttatgtacca ttgacattcc gattaacgcg aaataagaaa gataaaaaag
   116161 aaccagatta taaaaaggtt gtgaaaaata cgggtagcac tgagcgataa agaaaaagag
   116221 gaaatttatt gtcaaagtaa caactccgca actacttata tgggggacaa aaaatgatcg
   116281 aagaactaaa caagaaagat ttaccatggt ccttgttatt agatgcagat cctgataaag
   116341 aaaaagttca agtatatgtt tccagaggga gtggctggat atggaaagaa aaagaaaaaa
   116401 caataggtgt actgatctat gtggcaaggg aaaaagaata cgaaatcgtc aatgtagcag
   116461 taaccccaac gtatcaagga aaggggattg gcggaaaatt acttgagaca gcttttcaga
   116521 agctttcaca gctagcttca aaccaaactc ggatcattat acgtactggc actactagta
   116581 gcgctgcgtt acacctctat caaaaaatgg gctatgtgga gattggtcga gtcaaagact
   116641 attttatcca tcattactct gagcccattt ttgaaaatgg agatcaatta agggatcaag
   116701 tgattttagc aattcactta cctaaaaata gctttaacta ataaactttc aattcgagaa
   116761 aatgctttca aatgctaaat agatacatta caatagcttt agcaaacaaa aaggagaata
   116821 tttttatggg aatattagtt tttgattttg gtggatcggc tgtcaaatat ggttgttggg
   116881 atggcaaaga gattaaaggt aagggacaat ttgcaacgcc tgaatcttgg gaagaaatga
   116941 aaacgcaatt atttcaagtt tataaaaaaa tactcgtttc ttttgaagtc gaaggaattg
   117001 gaatcagctc tcctggagta gtgaataatg agaaacaggt gattgaggga atcagtgcga
   117061 ttccttatat tcatggattt aatattttcc gagatttgga aactctgttt caactcccag
   117121 taacgattga aaatgacgcc aactgtgccg gaatggctga attttatgaa ggtgctgccc
   117181 gtgattatca agatgttgct tttgttgtgg caggaactgg gattggcggg gcgttgttca
   117241 cgaaaggaca aataaataaa ggggcacatc tttacggtgg agaatttggg ttgatgttct
   117301 tagatggcga taagacattc agtaaacttg gtacagcggt acagatggct tggcgttatt
   117361 gtgaacgcaa aggtctcgat aaaaatgctt ataccggaaa agatgtcttt gaattagcag
   117421 aaactggaga tgcaatagca aaagaagaag ttgagagttt ttatacgtat cttacaaagg
   117481 gattattcag tattcaattt tcgtttgatc cagaagtgat cgtattaggc ggcggggttt
   117541 ctgcaaaaga agggctcatt gatgagatca aaagccgaat gaagaagctg acagaacaat
   117601 tcgatctgca tgatttcgaa ccgcagattt tattatgtga gtacagaaac gatgctaatc
   117661 ttataggtgc agcagcaaac tatctcgctg tacgtcaagg agagaattaa gagctttaga
   117721 gaaggtgcag cttgcataaa agaagagaat gaaatgaata ggagattttt acctaaggaa
   117781 tgttttattt gctgcagtat gataaaatat ctgagaggtg aaaatgatgt caaaaaaaaa
   117841 taaagatatt gaagtgcgta tagaagaagt gaaaaaagat atcaaaggta agaattatga
   117901 agtcactcag ttatttatag ggaaaaaaat gattggtgag atcttagcct atgggccaaa
   117961 agaatatgaa attttctttg gtgaagaaga ttttggaaaa gaaaaaagtc ttgaaaatgc
   118021 gatagaaaca gtgattcgac actggaatct gcacgaataa aaaaatatca aaaaaacttt
   118081 caataaaggg ttgcaaaaat ctggaaaatt aggtattata actaagtcag gttgatacaa
   118141 acctttcgga ggagtagcga agtggctaaa cgcgacggac tgtaaatccg ttccttaggg
   118201 ttcagtggtt cgaatccact ctcctccatt tcattggggt atagccaagc ggtaaggcaa
   118261 gggactttga ctccctcatg cgttggttcg aatccagcta ccccagtata ccacaatcgt
   118321 aagctctcgt tagttcgaga gctctttttt tttgctttgc taccttgttc cttgaagatt
   118381 ctgctgaatt aagatagagt taagttaact acaagaattg gagggatcca catgaaatgg
   118441 aaagaaaaag tagacgaagc agctgaaaag ttatatgatt tggtcaaatc agaaaaatac
   118501 aatattgaag tgaatattcc gaaaaaaggc ggaaaagcgg tccaggtaaa atcaaaacgc
   118561 ccaacgaatc atacaaaaaa atggatggct aaaaaccgct aataataaca aaagatccat
   118621 aagtcggcat tttcatcgat tttagggtct tttgttattt tctaggttga acatatctaa
   118681 aaaattgttt ctgacaatag gagtagggag aacgatgtgt gtctaaatcc tctgttgatg
   118741 gatagaaacc tttatctttt tcagttgtga atcaggtata taccagttat aatagaagaa
   118801 acgaaaggac gggtgtacgt tatgtcgaat caattacctg tatatataca gattcatgac
   118861 caattaaaaa atgaaatcga acaaggtata tggaaagtcg gagaccgtct tccttcagaa
   118921 agagaattag cagtgaaatt caatgtcagc cgtatgacgt tgagacaagc aattcaaaac
   118981 ttggcagatg aaggaatctt agaaagaaag atcggttcgg gtacgtatgt tgcgcgagaa
   119041 aaagtacaag aaaaaatgtc tggtgcaaca agttttacag aaattatgga atcacaaaat
   119101 cgagtaccgt ctagtcggac aatctcttat ttcttgactt cgccaagctc aagtgaaatg
   119161 gaaaaactaa acttgagtaa agatgacacg atcttgcgaa tggaacgtat tcgtttcgca
   119221 gatgatgtcc ctatttgttt tgaagttgcc agtgttccac aaaagctgat cgatggctac
   119281 agcaaagcag agattactga atcgttgtat cgcacgctag aagaaaaagg cgggaaaaag
   119341 atcggtccag cgaatcaaac gattactgct gtgttggctt ctgagaaaat tgctgactat
   119401 ttagaggtaa aacgaagaga tgcagttctt cgtttgcgcc agatttctta ttttgaagac
   119461 ggtacgccgt ttgagtatgt gcgtacgcaa tacgtaggaa atcgttttga gttttatttg
   119521 gaaaaataaa aaacaggtga tccctgattc cttattagaa ataaaagaga atcagaatca
   119581 cctgttttta tatatgatca gttatcagtt gctcgtgata agaaacagaa ccctcttcaa
   119641 attggacttg tccgttcagc agctcaatga tggattcttt aaagtggtta gcactttttt
   119701 catctacagc acagatgacg ctaacttgat cagtatattg gatttctttt ataaaaaaat
   119761 gttggagttc aagataattc tgtaattttc ctagttgcgg atacgtgatc atcacagaga
   119821 tctcctgttg caaggtacct tctacgattc caatgtcaga caatgcttga gagaccgcat
   119881 gagtgtatgc tcgtattaat ccgcctgtgc cgagtttcgt tcctccaaaa tatcgagtga
   119941 ctactgcagc tacattgatc agttgatttt ttttgaggac ttccaacatc ggtacgcccg
   120001 ccgttccact tggttctcca tcatcgctgc ttcgctggat ttcatttttt tctccaatga
   120061 tgaaggcgct gcagttatgg ttcgctttcc aatgttcttt ttttatttct tgaatgaaat
   120121 tttttgcttg gtcctctgat tctattcgtc taagagaaca gataaagcgt gattttttga
   120181 tctcaatctc actttgtcca ttttctttta ttgtacgata gcgctcgatc atcttgtcac
   120241 ctcttttttt cattttcttt attcagtata aataaagttc taggttgttt caacactgta
   120301 acggttgcgc aattgctgta gtatgcgata ataaagacaa aggcaggtgg atctggggat
   120361 gcaggaacga atgaaaaagt acgatgcaat tacgcattat ttgaagaaca atggcggctc
   120421 tcaagtaacg ttgaccttta cccaatttga cgaactgctg tttcccagta acggacttcc
   120481 caaaacagca agggaaagta cagattggtg ggcaaatgat tataaacacc ctgaaaaagg
   120541 tgcctatggc tggataaatg caggctatga agtagttgtc atcaatttgg acaaagaata
   120601 tgtcgtgttc aataaattag tgaaatctag ttggctattt gattaaataa accgcgttta
   120661 gaaaacgttg acaaatttct ttctttttat ataataaagt aacagacgcg aagaaaacgt
   120721 ttgcgtagtt tgttttaaaa aggagagaaa aatatggcta aaaaaacaat catgcttgta
   120781 tgttcggctg gtatgagcac aagtttacta gtaacaaaaa tgcaaaaagc tgctgaagca
   120841 aaaggaatcg actctgatat tttcgctgtg tccgcttctg acgcagataa caatcttgca
   120901 aataaagacg tggatgtgtt gttattaggc ccacaagttc gctttatgaa agctgatttt
   120961 gagaaacgtc tggaaccaaa aggcattcct ttagatgtca tcaatatggc tgattatggt
   121021 atgatgaatg gcgaaaaagt gttagatcaa gcaatcgcgc tcataggtga ataaatagaa
   121081 cagtataact atcgaacaag cgatccaaaa aatagatcgc ttgttttttc gtatattttt
   121141 ttagggcgaa taatatgaat catttttggg gtagaaggct tctgacgaga gatattaaag
   121201 caatagactg tgaggaggta aatttaccaa attatgagaa gatcgcagca gtggaacgtt
   121261 tgggcaactg gattctttgt catcgctgtg gaatgaggac gtccgtcatt gttggacagc
   121321 ttgcagatta cggttatttt tgtacacatt gtctatattt agggtgatgc gacactcaac
   121381 aagatttata tttgtttgat cagcctgaag caaaacctcg agaagtcgtc tttttttgga
   121441 caggacagct tactgaaaaa caaacggaaa tcgcaaagag aatactttgc cattcagaaa
   121501 aaagacatca tcttatttgg gctgtaacag gtgcagggaa aacagagatg ctttatccta
   121561 ttttagtgga aactttaaaa gctggaggaa gagtagcgat ttgtacaccg cgagtcgatg
   121621 tttgtaatga attgttttta cgctatcgtt atgtttttcc agaagaaaaa atcacgttgc
   121681 tccatgggaa tacagcaacg gcttatacct ttacttcttt tgttatctgt acgattcatc
   121741 agctataccg tttttatcgg tcctttgatt taatagtgat cgatgagatc gatgcgtttc
   121801 cttataacgg ggatgctggg ctagctcacg ctgtgcaaac agcaatcaga tcaaacggcc
   121861 gattcatcta cttaagtgcc acgcctgatg agaagttact aaaggaaatc aagcagacat
   121921 ttgagctcca caaacttgcc ttgcgctttc atcggcgctt gcttcctgaa cccgtgcttg
   121981 ttttcatgaa taattggcga caaaaatgtg gaaacaaaaa gaaaatcaac tctttggtgc
   122041 ggatcattca gcaactaatc aaagaaaacc gtatcctttt attttgtcca agtattacga
   122101 tgatgcatcg tttaaaaatc acactgcaag aagcttttcc agaatatgag ataacagatg
   122161 tttcttcaca agacgatcaa cgggcaaaga aagttcagaa aatgcgagaa gcaatatacg
   122221 agatactgtt aaccacaatg atcctagaaa gaggagtcac atttgaaaga atctctgtca
   122281 tcgttttagg agcagatcat ccagttttta ctaaatcctc tttggtgcaa atcgcaggaa
   122341 gagctgatcg taaaggtcct tatacgaaca gtcgagtcta ttttttctat gaagaaaaaa
   122401 cttcagctat tcgaaaagcc tgtcaggaaa tcaaagaaat gaacgaagaa gggaagcaga
   122461 tgctgtgaga tgtagttgct gcggtaaaga catcattcaa aatttaacat tcagcgagat
   122521 catcggagtg tcgaaatcta gacttcctca gacatgttca gtttgccgcg cacaattcca
   122581 tttattagaa gcaaaaggtt gtgcaggttg tcaaaaacca atccatttga aatacgagga
   122641 gacgaaaaag aaagcaaata ctagtttcgt ttactgcaac gactgtcaag aatggaagaa
   122701 gaaatatcct gcatatgatt ttcaacaccg cgcctttttt acgtacgatg aaaagatgca
   122761 ggcttggatc aatcggtaca agtttatggg agatatccga ttagcaggga cttttgcata
   122821 taaatggact cagataaaaa aagattaccc ggcatatatt tattgtccaa tacctttatc
   122881 tgaaaaaagg tggctagaaa gaggattcaa tcaagtaagc gagatgttga aagcagcaaa
   122941 aattcctttt cagatgctgc tcaaaagaga gcaacatctg cttgctcaag caaaaaacac
   123001 gcgaaaggaa agattggaga tgcctcagcc ttttgagctt gccgtacctc tttctaagat
   123061 acaacataaa aaaatattga ttattgacga tgtctataca acaggacaga cgctttttca
   123121 tgcagcagat tgcttgcaga acgcacagcc gaaaatcatc cgaaccattt ctttggcaag
   123181 atgaatcaga tgtggaaatt tgatagc
//
LOCUS       DBBGSZ010000004       112928 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.004, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000004 DBBGSZ010000000
VERSION     DBBGSZ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 112928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 112928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..112928
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.004"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(99..1229)
                     /locus_tag="ACIZE5_000380"
     CDS             complement(99..1229)
                     /locus_tag="ACIZE5_000380"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HGC6107557.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="ACIZE5_000381"
     CDS             complement(1878..3080)
                     /locus_tag="ACIZE5_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6107558.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="ACIZE5_000382"
     CDS             complement(3140..3343)
                     /locus_tag="ACIZE5_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HGC6107559.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4552)
                     /locus_tag="ACIZE5_000383"
     CDS             complement(3485..4552)
                     /locus_tag="ACIZE5_000383"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGC6107560.1"
                     /translation="MLDSLQEEVVPVNRVLIDYLTIHFFSNQHLKLIEEIIEMPIERF
                     EELDYAPKGYIGQYVWNQVITIRYSIDDAVKGTVMEFSGQGCKHLARWLKTRKTNWQQ
                     FFRKVLDYQGNFTRIDFTLDDFVGSLSIPELKHKVILGHVWTTFQVSESHGGTDIINN
                     ESNGETLYLGSKKSQCRFCFYQKDHEQRKRRGIPLEEAKVKNRFELRYRKEKAQSLAK
                     IISKTHDLTKLFFELLNGAICFYDRDPNDLGAKVDAKWAAFISNYGAITISLDTIPQS
                     FEKTMSWLIHGVSPSLVFIAQVDQTFHSSLLPLIIEQGEMNPRQIKLLQNMKADPEYY
                     QEEVEYYERKLQSISNEKTSY"
     gene            complement(4610..4717)
                     /locus_tag="ACIZE5_000384"
     CDS             complement(4610..4717)
                     /locus_tag="ACIZE5_000384"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6107561.1"
                     /translation="MNQVNQHDLGEAIRVSREERGWTQRYLAEKVGISR"
     gene            4880..5692
                     /locus_tag="ACIZE5_000385"
     CDS             4880..5692
                     /locus_tag="ACIZE5_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6107562.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6066..6257)
                     /locus_tag="ACIZE5_000386"
     CDS             complement(6066..6257)
                     /locus_tag="ACIZE5_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107563.1"
                     /translation="MKQKFFIAIIATKKFHRGKRFGQKWKFPPKVTAPQLKSIKELEF
                     ENALVICMTCTDEVFRKHF"
     gene            complement(6502..6732)
                     /locus_tag="ACIZE5_000387"
     CDS             complement(6502..6732)
                     /locus_tag="ACIZE5_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107564.1"
                     /translation="MNFFGDRFFQPYKINRNSIIESCDYKKIARKKKKVSIHFKYFIP
                     ISIAKKVEILYLPLTLASLANVVSILIDNKLR"
     gene            complement(6716..6913)
                     /locus_tag="ACIZE5_000388"
     CDS             complement(6716..6913)
                     /locus_tag="ACIZE5_000388"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HGC6107565.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            complement(7059..7937)
                     /locus_tag="ACIZE5_000389"
     CDS             complement(7059..7937)
                     /locus_tag="ACIZE5_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGC6107566.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7976..9094)
                     /locus_tag="ACIZE5_000390"
     CDS             complement(7976..9094)
                     /locus_tag="ACIZE5_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HGC6107567.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9091..11190)
                     /locus_tag="ACIZE5_000391"
     CDS             complement(9091..11190)
                     /locus_tag="ACIZE5_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HGC6107568.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11241..12062)
                     /locus_tag="ACIZE5_000392"
     CDS             complement(11241..12062)
                     /locus_tag="ACIZE5_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGC6107569.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12059..12868)
                     /locus_tag="ACIZE5_000393"
     CDS             complement(12059..12868)
                     /locus_tag="ACIZE5_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGC6107570.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12889..13383)
                     /locus_tag="ACIZE5_000394"
     CDS             complement(12889..13383)
                     /locus_tag="ACIZE5_000394"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC6107571.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13395..13895)
                     /locus_tag="ACIZE5_000395"
     CDS             complement(13395..13895)
                     /locus_tag="ACIZE5_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC6107572.1"
                     /translation="MIKPMFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLS
                     SIQLLTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITK
                     TFLEKEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVN
                     EEEDFF"
     gene            complement(13960..16656)
                     /locus_tag="ACIZE5_000396"
     CDS             complement(13960..16656)
                     /locus_tag="ACIZE5_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGC6107573.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRT
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17084..18157)
                     /locus_tag="ACIZE5_000397"
     CDS             complement(17084..18157)
                     /locus_tag="ACIZE5_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6107574.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18154..18981)
                     /locus_tag="ACIZE5_000398"
     CDS             complement(18154..18981)
                     /locus_tag="ACIZE5_000398"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6107575.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18982..19788)
                     /locus_tag="ACIZE5_000399"
     CDS             complement(18982..19788)
                     /locus_tag="ACIZE5_000399"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6107576.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19800..20885)
                     /locus_tag="ACIZE5_000400"
     CDS             complement(19800..20885)
                     /locus_tag="ACIZE5_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6107577.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20902..21444)
                     /locus_tag="ACIZE5_000401"
     CDS             complement(20902..21444)
                     /locus_tag="ACIZE5_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HGC6107578.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21702..22691
                     /locus_tag="ACIZE5_000402"
     CDS             21702..22691
                     /locus_tag="ACIZE5_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HGC6107579.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22688..23425
                     /locus_tag="ACIZE5_000403"
     CDS             22688..23425
                     /locus_tag="ACIZE5_000403"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HGC6107580.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23422..23973
                     /gene="coaC"
                     /locus_tag="ACIZE5_000404"
     CDS             23422..23973
                     /gene="coaC"
                     /locus_tag="ACIZE5_000404"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HGC6107581.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23989..24621
                     /locus_tag="ACIZE5_000405"
     CDS             23989..24621
                     /locus_tag="ACIZE5_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGC6107582.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24706..25353
                     /locus_tag="ACIZE5_000406"
     CDS             24706..25353
                     /locus_tag="ACIZE5_000406"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding oxidoreductase"
                     /protein_id="HGC6107583.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25358..26341
                     /locus_tag="ACIZE5_000407"
     CDS             25358..26341
                     /locus_tag="ACIZE5_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HGC6107584.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(26744..28258)
                     /locus_tag="ACIZE5_000408"
     CDS             complement(26744..28258)
                     /locus_tag="ACIZE5_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HGC6107585.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28396..29202
                     /locus_tag="ACIZE5_000409"
     CDS             28396..29202
                     /locus_tag="ACIZE5_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107586.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWVFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29377..29946)
                     /locus_tag="ACIZE5_000410"
     CDS             complement(29377..29946)
                     /locus_tag="ACIZE5_000410"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6107587.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKSDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30029..32089)
                     /locus_tag="ACIZE5_000411"
     CDS             complement(30029..32089)
                     /locus_tag="ACIZE5_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HGC6107588.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(32366..33844)
                     /locus_tag="ACIZE5_000412"
     CDS             complement(32366..33844)
                     /locus_tag="ACIZE5_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6107589.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(34142..35077)
                     /gene="murB"
                     /locus_tag="ACIZE5_000413"
     CDS             complement(34142..35077)
                     /gene="murB"
                     /locus_tag="ACIZE5_000413"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HGC6107590.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(35150..36070)
                     /locus_tag="ACIZE5_000414"
     CDS             complement(35150..36070)
                     /locus_tag="ACIZE5_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC6107591.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            36183..36935
                     /locus_tag="ACIZE5_000415"
     CDS             36183..36935
                     /locus_tag="ACIZE5_000415"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HGC6107592.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            37799..38332
                     /locus_tag="ACIZE5_000416"
     CDS             37799..38332
                     /locus_tag="ACIZE5_000416"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HGC6107593.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(38822..39346)
                     /locus_tag="ACIZE5_000417"
     CDS             complement(38822..39346)
                     /locus_tag="ACIZE5_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGC6107594.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(39339..39812)
                     /gene="tsaE"
                     /locus_tag="ACIZE5_000418"
     CDS             complement(39339..39812)
                     /gene="tsaE"
                     /locus_tag="ACIZE5_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HGC6107595.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(39935..40915)
                     /gene="pta"
                     /locus_tag="ACIZE5_000419"
     CDS             complement(39935..40915)
                     /gene="pta"
                     /locus_tag="ACIZE5_000419"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HGC6107596.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(41068..41748)
                     /locus_tag="ACIZE5_000420"
     CDS             complement(41068..41748)
                     /locus_tag="ACIZE5_000420"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HGC6107597.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            41874..42743
                     /locus_tag="ACIZE5_000421"
     CDS             41874..42743
                     /locus_tag="ACIZE5_000421"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC6107598.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            42769..43284
                     /locus_tag="ACIZE5_000422"
     CDS             42769..43284
                     /locus_tag="ACIZE5_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HGC6107599.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(43331..43894)
                     /locus_tag="ACIZE5_000423"
     CDS             complement(43331..43894)
                     /locus_tag="ACIZE5_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6107600.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(43949..44128)
                     /locus_tag="ACIZE5_000424"
     CDS             complement(43949..44128)
                     /locus_tag="ACIZE5_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107601.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(44205..44714)
                     /locus_tag="ACIZE5_000425"
     CDS             complement(44205..44714)
                     /locus_tag="ACIZE5_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107602.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(44810..45190)
                     /locus_tag="ACIZE5_000426"
     CDS             complement(44810..45190)
                     /locus_tag="ACIZE5_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC6107603.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            45520..46269
                     /gene="pnuC"
                     /locus_tag="ACIZE5_000427"
     CDS             45520..46269
                     /gene="pnuC"
                     /locus_tag="ACIZE5_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HGC6107604.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(46453..47730)
                     /locus_tag="ACIZE5_000428"
     CDS             complement(46453..47730)
                     /locus_tag="ACIZE5_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107605.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(47809..48453)
                     /gene="pcp"
                     /locus_tag="ACIZE5_000429"
     CDS             complement(47809..48453)
                     /gene="pcp"
                     /locus_tag="ACIZE5_000429"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGC6107606.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(48652..49596)
                     /locus_tag="ACIZE5_000430"
     CDS             complement(48652..49596)
                     /locus_tag="ACIZE5_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HGC6107607.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(49598..50284)
                     /locus_tag="ACIZE5_000431"
     CDS             complement(49598..50284)
                     /locus_tag="ACIZE5_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HGC6107608.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            50758..51078
                     /locus_tag="ACIZE5_000432"
     CDS             50758..51078
                     /locus_tag="ACIZE5_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HGC6107609.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            51232..52137
                     /locus_tag="ACIZE5_000433"
     CDS             51232..52137
                     /locus_tag="ACIZE5_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6107610.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            52134..52907
                     /locus_tag="ACIZE5_000434"
     CDS             52134..52907
                     /locus_tag="ACIZE5_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGC6107611.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(53088..54512)
                     /locus_tag="ACIZE5_000435"
     CDS             complement(53088..54512)
                     /locus_tag="ACIZE5_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HGC6107612.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            54723..55169
                     /gene="nrdI"
                     /locus_tag="ACIZE5_000436"
     CDS             54723..55169
                     /gene="nrdI"
                     /locus_tag="ACIZE5_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HGC6107613.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(55234..57216)
                     /locus_tag="ACIZE5_000437"
     CDS             complement(55234..57216)
                     /locus_tag="ACIZE5_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HGC6107614.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(57230..58126)
                     /gene="murQ"
                     /locus_tag="ACIZE5_000438"
     CDS             complement(57230..58126)
                     /gene="murQ"
                     /locus_tag="ACIZE5_000438"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HGC6107615.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(58129..59190)
                     /locus_tag="ACIZE5_000439"
     CDS             complement(58129..59190)
                     /locus_tag="ACIZE5_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HGC6107616.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(59401..59928)
                     /locus_tag="ACIZE5_000440"
     CDS             complement(59401..59928)
                     /locus_tag="ACIZE5_000440"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGC6107617.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(59995..61497)
                     /gene="eat(A)"
                     /locus_tag="ACIZE5_000441"
     CDS             complement(59995..61497)
                     /gene="eat(A)"
                     /locus_tag="ACIZE5_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HGC6107618.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(61755..62876)
                     /locus_tag="ACIZE5_000442"
     CDS             complement(61755..62876)
                     /locus_tag="ACIZE5_000442"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HGC6107619.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            63002..63943
                     /locus_tag="ACIZE5_000443"
     CDS             63002..63943
                     /locus_tag="ACIZE5_000443"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HGC6107620.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(64093..64989)
                     /locus_tag="ACIZE5_000444"
     CDS             complement(64093..64989)
                     /locus_tag="ACIZE5_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HGC6107621.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            65258..66598
                     /locus_tag="ACIZE5_000445"
     CDS             65258..66598
                     /locus_tag="ACIZE5_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HGC6107622.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            66816..67259
                     /locus_tag="ACIZE5_000446"
     CDS             66816..67259
                     /locus_tag="ACIZE5_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HGC6107623.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(67763..69181)
                     /gene="nhaC"
                     /locus_tag="ACIZE5_000447"
     CDS             complement(67763..69181)
                     /gene="nhaC"
                     /locus_tag="ACIZE5_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HGC6107624.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(69584..70807)
                     /locus_tag="ACIZE5_000448"
     CDS             complement(69584..70807)
                     /locus_tag="ACIZE5_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGC6107625.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(70838..71677)
                     /locus_tag="ACIZE5_000449"
     CDS             complement(70838..71677)
                     /locus_tag="ACIZE5_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGC6107626.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(71694..72374)
                     /locus_tag="ACIZE5_000450"
     CDS             complement(71694..72374)
                     /locus_tag="ACIZE5_000450"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HGC6107627.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(72376..73449)
                     /locus_tag="ACIZE5_000451"
     CDS             complement(72376..73449)
                     /locus_tag="ACIZE5_000451"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HGC6107628.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(73505..73743)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(73786..74019)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(74096..74767)
                     /locus_tag="ACIZE5_000452"
     CDS             complement(74096..74767)
                     /locus_tag="ACIZE5_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC6107629.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(74854..77502)
                     /gene="mgtA"
                     /locus_tag="ACIZE5_000453"
     CDS             complement(74854..77502)
                     /gene="mgtA"
                     /locus_tag="ACIZE5_000453"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HGC6107630.1"
                     /translation="MEKKKDTQKIYAAFAGKTKQELFELFHASANGLTEEQIERSREN
                     YGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPGDKDLFGVAII
                     FTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEEIVCGDLVRLS
                     AGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSYENLVFMGSNV
                     ISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKFMSLMAPAVIV
                     INGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGTVIKNLNAIQN
                     FGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQTGLKNLLDVAI
                     IDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGAIEEMLNISKF
                     IDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFSVKDESDMVLI
                     GYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLEINELVTGEKI
                     SEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGINDAPAMKVADI
                     GISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKATASSNFGNMFS
                     VLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKWNASSIGEFMV
                     YFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAGWFVESLWTQT
                     LVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLMPLPGNYWLWL
                     FATVIAYLALVTAVKKIYIRRFQELL"
     regulatory      complement(77844..78018)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            78191..78628
                     /gene="ndk"
                     /locus_tag="ACIZE5_000454"
     CDS             78191..78628
                     /gene="ndk"
                     /locus_tag="ACIZE5_000454"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HGC6107631.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(78650..79516)
                     /locus_tag="ACIZE5_000455"
     CDS             complement(78650..79516)
                     /locus_tag="ACIZE5_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HGC6107632.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLSHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(79676..81769)
                     /locus_tag="ACIZE5_000456"
     CDS             complement(79676..81769)
                     /locus_tag="ACIZE5_000456"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HGC6107633.1"
                     /translation="MTQLKKMCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(82518..83141)
                     /locus_tag="ACIZE5_000457"
     CDS             complement(82518..83141)
                     /locus_tag="ACIZE5_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107634.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(83300..84697)
                     /locus_tag="ACIZE5_000458"
     CDS             complement(83300..84697)
                     /locus_tag="ACIZE5_000458"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC6107635.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(84729..85700)
                     /locus_tag="ACIZE5_000459"
     CDS             complement(84729..85700)
                     /locus_tag="ACIZE5_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6107636.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            86074..86499
                     /locus_tag="ACIZE5_000460"
     CDS             86074..86499
                     /locus_tag="ACIZE5_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107637.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(86987..87688)
                     /locus_tag="ACIZE5_000461"
     CDS             complement(86987..87688)
                     /locus_tag="ACIZE5_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HGC6107638.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(87704..88144)
                     /locus_tag="ACIZE5_000462"
     CDS             complement(87704..88144)
                     /locus_tag="ACIZE5_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HGC6107639.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(88144..88719)
                     /locus_tag="ACIZE5_000463"
     CDS             complement(88144..88719)
                     /locus_tag="ACIZE5_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HGC6107640.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            88960..89169
                     /locus_tag="ACIZE5_000464"
     CDS             88960..89169
                     /locus_tag="ACIZE5_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit beta"
                     /protein_id="HGC6107641.1"
                     /translation="MYYFKQQILVSFINEKIILFSCYVSLINDVSLNKKADELNDQNL
                     IIFVHQLLLKIFLLTINSWICKNIT"
     gene            complement(89567..90079)
                     /locus_tag="ACIZE5_000465"
                     /pseudo
     CDS             complement(89567..90079)
                     /locus_tag="ACIZE5_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014566402.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(90205..90906)
                     /locus_tag="ACIZE5_000466"
     CDS             complement(90205..90906)
                     /locus_tag="ACIZE5_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6107642.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(91014..92457)
                     /locus_tag="ACIZE5_000467"
                     /pseudo
     CDS             complement(91014..92457)
                     /locus_tag="ACIZE5_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            complement(92471..94336)
                     /locus_tag="ACIZE5_000468"
     CDS             complement(92471..94336)
                     /locus_tag="ACIZE5_000468"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGC6107643.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(94457..95307)
                     /gene="licT"
                     /locus_tag="ACIZE5_000469"
                     /pseudo
     CDS             complement(94457..95307)
                     /gene="licT"
                     /locus_tag="ACIZE5_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
     gene            complement(95617..96330)
                     /locus_tag="ACIZE5_000470"
     CDS             complement(95617..96330)
                     /locus_tag="ACIZE5_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HGC6107644.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(96398..96724)
                     /locus_tag="ACIZE5_000471"
     CDS             complement(96398..96724)
                     /locus_tag="ACIZE5_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HGC6107645.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(96847..97074)
                     /locus_tag="ACIZE5_000472"
     CDS             complement(96847..97074)
                     /locus_tag="ACIZE5_000472"
                     /inference="COORDINATES: protein motif:HMM:NF013777.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HGC6107646.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(97396..98649)
                     /locus_tag="ACIZE5_000473"
     CDS             complement(97396..98649)
                     /locus_tag="ACIZE5_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HGC6107647.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            98710..99450
                     /locus_tag="ACIZE5_000474"
     CDS             98710..99450
                     /locus_tag="ACIZE5_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HGC6107648.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(99536..100294)
                     /locus_tag="ACIZE5_000475"
     CDS             complement(99536..100294)
                     /locus_tag="ACIZE5_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HGC6107649.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(100291..100755)
                     /locus_tag="ACIZE5_000476"
                     /pseudo
     CDS             complement(100291..100755)
                     /locus_tag="ACIZE5_000476"
                     /inference="COORDINATES: protein motif:HMM:NF023225.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
     gene            complement(100774..101271)
                     /locus_tag="ACIZE5_000477"
     CDS             complement(100774..101271)
                     /locus_tag="ACIZE5_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HGC6107650.1"
                     /translation="MILLLGFILWQTPVHASEFNFAVDFELPANQIDKNKTYINVRME
                     PGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESKSKFDETLSYDMKNLAK
                     TVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKENVSNKSTVGVVNQFSQV
                     KAILI"
     gene            complement(101339..104506)
                     /locus_tag="ACIZE5_000478"
     CDS             complement(101339..104506)
                     /locus_tag="ACIZE5_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HGC6107651.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            complement(104730..105614)
                     /locus_tag="ACIZE5_000479"
     CDS             complement(104730..105614)
                     /locus_tag="ACIZE5_000479"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGC6107652.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(105709..106146)
                     /locus_tag="ACIZE5_000480"
     CDS             complement(105709..106146)
                     /locus_tag="ACIZE5_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107653.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            complement(106363..107274)
                     /locus_tag="ACIZE5_000481"
     CDS             complement(106363..107274)
                     /locus_tag="ACIZE5_000481"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGC6107654.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(107731..108159)
                     /locus_tag="ACIZE5_000482"
     CDS             complement(107731..108159)
                     /locus_tag="ACIZE5_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107655.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(108187..108825)
                     /locus_tag="ACIZE5_000483"
     CDS             complement(108187..108825)
                     /locus_tag="ACIZE5_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6107656.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(108829..110865)
                     /locus_tag="ACIZE5_000484"
     CDS             complement(108829..110865)
                     /locus_tag="ACIZE5_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HGC6107657.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLF
                     TDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLL
                     MNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYV
                     FLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFS
                     SSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSI
                     LVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRH
                     TDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSM
                     YLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLS
                     RSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNL
                     IKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            110991..111656
                     /locus_tag="ACIZE5_000485"
     CDS             110991..111656
                     /locus_tag="ACIZE5_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6107658.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
BASE COUNT        33147 a        23422 c        19243 g        37116 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaaccg tttttcaatc
     7381 gctggtcctg ctgccatccc ctctaaacaa tcttggtgga agggacagtt tcctgaaaaa
     7441 ttgtcctttg gatgtcgctt gatcaacata tgccccattt ccggatgact gaacccttcc
     7501 acgaaagtcc cattgaacaa ggcaccacct ccgatacctg ttcccacagt gaagtatgca
     7561 acacctgcta accctttgcc agaaccagca acatattcac catagcaagc cgcattgaca
     7621 tctgttgtcc attcaatcgg aatattgaaa tattgcttta gcgttcctac aaaattgaaa
     7681 ttttgccaag caagttttgg tgttgatgtg atatgaccga aactcgttga tttgcattga
     7741 atatcaattg gaccaaagca gccgaccccg atgcctgcca attgttcctt aaaaggttta
     7801 aaaaaatcaa tgacctgctt cattgtttca actggagttg ttgtgggaaa actgactctt
     7861 tccaaaatcg ttaattcctc agtaccgact gcacagacaa atttagtccc tccagcttca
     7921 attgccccat atatcatcat aggttcctcc cttcgaatat gtgaaaaaca cttcattaac
     7981 gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt tcctgaagct tctgttgaat
     8041 accagtaagc gacactagca acatcgtctt gccgctcaaa taagcgaaca tcatcgttgc
     8101 cgatttgttg taaagtgacc gataaatctt cggtaaaaca gatggggtct tgaagatgcc
     8161 aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa ggcatgaacg gcattcaatt
     8221 ttcccgtttc aaaacgatct cttgtggcat ctctatttga ttggtaagga taccctaaaa
     8281 aggctgttga atagtttttc gcatgtggac gtccgaactc atcgtactca tgaaaggccc
     8341 acgccccgcc aaaataatct tctgaacctg ttgaggttac ggtcggatac tcactatccc
     8401 catcaatgta gaatttaaac tcgccttcgc cccaccaata acgttctagg caggtaagcg
     8461 caaggtaagt acccacgtaa tagccttgac cctttaatcg atcaattaac ttataatcct
     8521 cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg aaaatatagg ctattttctt
     8581 ccaattcgtc caccaaagcg taatttatcg tataaaaaaa tgaggacata tccttcggat
     8641 gtaaattctc gatcgtaatt ttagcggatg tttggaaagg catttcgaaa taggaattaa
     8701 agccccctgt aggattaacc actatcggca acgagttcac ctcgcaacgc tctccaaacc
     8761 cattacaaaa gaaatcccct aaaggacttt caacagcagg gctatccgac ccatcccaat
     8821 aaattcttaa gattaaatca cgtaaaacaa aactgccaaa ttctgttcga tcacgaatcg
     8881 tcatccacat atgacgaatt attcccgttc cagtaatatc cgcaatcaca gtttcttcac
     8941 cagaagtcag cggaattgcg ccacgacctt tgcggcttgg tcctagctcg cttggcaaca
     9001 tcgcagcttt acctttctcg cctgttggat tttcgggagt gattgctcga ctctggattt
     9061 ttttaaattg ggtaatattt tttagtatac tcatcttttt ctcctttgaa tgtgaatcgt
     9121 ttttcccttt tctacgtgaa gaattttttt cgtatcactt attttcaatg gcttttctga
     9181 caaatttgaa atactcaact cggattgcgt acattcaatc gaaatgaagg cttgaccgaa
     9241 cttcaaattc ttccaagaaa acgttaaatt atcaacagga tcaatttgca atactccttt
     9301 tttgaatttc aatccgaaat attgactgat cattaggctg acaaaaagac ccgatgccca
     9361 gccgcatttg ccgcagccaa agtctcgcac gacttctcct tgttgagcct ctaagcgata
     9421 cggccaccac caccacgaac cgtctaaatc tgccaaacaa attagttctt ctaatcgggt
     9481 tacgaaagct tgagggttgt gcagctcgct cattaaaaca gtgataaagc caggaaaagt
     9541 ggcgccggat tctaatcccc aagtgatgcc tttgatttcc tcgctatagg ttggattgaa
     9601 agaactagca gaaaaggcca tggtgttctg atataaatga tctttattat ctaaaaattg
     9661 ataaaaaggc atcaacgtag tgtctgattc ttctccatca tgcatcaata aattaatttt
     9721 tccatccaca atcacatcac ttaaaaagat taacccttgc tcaagaatcg gtttttgata
     9781 gtgcttcact gaataggttg ttttctcctc atcaccgatt ccctccaaaa attgctcacc
     9841 aaaaggacca tcgatagtca tttgtttaca aattgattcc tttagtttac aggcaatgtt
     9901 tttgtatcgc ttgctaagac tcagttgttc tagggcttca aaaatttctg caagtccaat
     9961 acaggccttc caaagacaaa gattgctgcc ggtatgatac tttccaagtg caaaggcgtc
    10021 tgataaccaa acagatggaa aaagcattgg ttcccctgac cgacgttgag ctaatatgtc
    10081 ctcaataatt cttgaagcat tcagtagaac ctgcggacac cgctcaaaga attttgtatc
    10141 cccagtatgt tcaaaataaa gactagccag taacgcactg gataacgaat tactcagaga
    10201 atgattgata cctcctgtaa attttgaacc aggaaactta acgccatatt gatcaaacca
    10261 tagaaccgtt ttttgacata actccggttc aaacatggtg aatggcaatg atgcgtaata
    10321 catatcctta ttccaaattc gattagtagc aggatagctg ccccaattgc tgccgacgac
    10381 ctgtccctgt cgattcatac cgaaactaga aaagctttga taaagtgcac gacgatagag
    10441 atggacaact ctatcgtttg gcattgacag ctgcccaaat agctgagcaa aatagttcaa
    10501 tgtttccttc agccattttt cgatatcaga ttcctgaaaa gtcattactt cttcaaaagc
    10561 atttgggtcc acaaaagcaa tggcgaagct tgccacttcc tgttgtgcga tcgtgtcctt
    10621 atttcctttt tgagaaatca acacattttg ctgatccgaa tacttctctt gatacgaagg
    10681 cacatctttc actgaaactt gaaggctttc gtgtgtttca ttcacaatgt aaacctgttg
    10741 aacaagcata cttaaacgct tattagccag tatgggagca aaggatacta caatgacctt
    10801 aaacgtcgaa taatgatgaa tatatctagg caaacagtct tgaatcacat cgacttcaat
    10861 acgatgatcc gattctgaca aatggtagac aatcccgttt acttcaacct ttaaggataa
    10921 cgaattggtt tgagagagct gtttattgac ccaaacacct ggtttttcct cagttagtaa
    10981 attttctcga taaaaggtca acgtttgaat cgtcccgcaa acatcaaggt ttgctaatgt
    11041 cttttgatta cttacatcga aggtcaatcc ctttacatca ggaatattcc gatagtagct
    11101 gtattcgttt gaagtagtca catttccgtc gtttaactca gcattaaaaa atgggtgttt
    11161 gggtgaataa attacttcat taatagtcat cttttccctc cttgctaaaa aaactgcagc
    11221 ctagtagctg cagcttccta ctatgcgatt ccaagtaatg acaataaaat tcccaagacg
    11281 accattccaa aaataatttt gatgacgccg acttttttat ctagtaattt gaaacagctc
    11341 aatgttacca ataacggtac aattccttta aaaatactat cgaggatttc ttggacattc
    11401 attagttctt cgcccttcat tgaaaagctc aaaacggtat tgaatttgac catactgatc
    11461 gtcattgcac ctaccatgat cagacccaag atactagcag cttttgtcag aatttcaatt
    11521 aacccgttcg catacagctt ttcaatatat ttagagccta atgaatagcc taaaacgccg
    11581 ccatagtatc gcatcaagta attaggtata ttgaacataa ctaaaaagat aattggtgcc
    11641 aaaatatttc cggcattggc taagttgatc gctagtcccg cggtaacgac acgccaaact
    11701 ccccagaaca atgaatcgcc aattccagcc aatggtccca tcaaactcgt tttgatcgcg
    11761 ttgatacttt ccacgtcaaa accagctttt tcagaatttt ccttctccat cgatgccgca
    11821 atccccatga caaaggacgc gcaaggaatg gtcgtcgaaa aatactgtgt atgacgttcc
    11881 agcgccgcag ctcgatcttc ttcacttttg tagaaatgat taatgaaggg catcatagaa
    11941 taggcgaaac caccgccgcc catcgtcacc ggattcaccg aagcatacat agtcatcgag
    12001 cgccaaaaca tcttccgaac caattttttc tcatctttag aaattccatc agctaatttc
    12061 attgaaagaa atcctcctct tcttggtcaa gcgttgcatt tacagcagca tcgctttgaa
    12121 ctgcatgaac agatatattt tttagttgta gatctctttg ggctataaca attgcaataa
    12181 tcgttccaac tgcggcaatt gcaatcaatg gtaactcgag atacgccata acaacggccc
    12241 caaagaaaaa ccacacagca atatttttac tccaaagcat ccgtaacagc atcgccatcc
    12301 caactgccgg cagcagattt ccagcgactg ttaatccgtt catgatgacc tctggaatat
    12361 tatccaagac gcttttgaca acatctgctc caaataaaac ggcaaagaat ggaataagag
    12421 cataaagcgc atagtggaca aaccacataa agaagtgcag attgatgatt cctttttgat
    12481 caccagattt tgcaaatttg aaaaatttag cagccatcgg tccacataca aaagaaaaaa
    12541 tcatattcat taactgtaat cctaatactg ctagtggaaa gacaatggga ataatcgcat
    12601 ccacgtttcc tcccattttg attgcgaacg ctgtagccag cccagcagcc aaagaaggct
    12661 ccgccgtact agagattccg atattgacga cacccataaa gatggcttct agtgacgccc
    12721 cgacaatcaa ccccgtctgc aaatccccca tcaacgctcc tgctaacgga gcaacaacaa
    12781 tcggacgact cagcatggac atcccgaaca tttcatgtcc agcaactcca ataaaaacgg
    12841 ccaaagcgac tacaaatgca tcatacataa tttttctcct tcctttttct aaaaatcact
    12901 caaaatagag atagctgaac gtttttccat cgccggtgta ggctgaaaaa cggtatctgg
    12961 ataaagttca actaattctt ttaagtcttg aatttctgac gtcgttaaca tcacttcctt
    13021 tgataaggtt ttcttatctt ccgatggcgg tgtcattttc ccagcattcc ccacgttcat
    13081 taattcgatt tccgttggga aagctttcgc aacttttacc gcatctttga cattagggac
    13141 taaaaccatc aagcgcatgt ccttcgcccg cggatctttt aacaaatgaa tcgcgtcatc
    13201 aactgtttta ataatgactt tgacattcga tggtgcagcc atcttcaatg tcatcttttg
    13261 aatatcgttg gtagccgcct catcgcttgc tactactaac ccggttaaat ttagactctt
    13321 tgtccaagtc atcgctactt gtccatgaat taatcgttca tcaattcgca ctgctttaat
    13381 catttttctt cctcctaaaa aaaatcttcc tcttcattta ctacatgtac ctcatcaaga
    13441 atggtcatct ttaattcctg ttggcattta tttaccagtt cctgaatatc ctcctttgtt
    13501 aattccttgg ttgccaatac tatttcgagc agaattggca gattaaagcc agacaaaata
    13561 gttacagcaa tctctttctc caaaaaggtt ttggtaatct tctgattgac acttccgcca
    13621 aataaatcgg taaaaacaaa aatctgatcc tgctcgttca cctggtttac aaatacattc
    13681 aactcctgtt caaaatcaca ctcatccaca taagcattaa tcaccgtaat ctcttgaacc
    13741 ttccccgtca gtaattgaat actgctaaga aagcctgaag ctaagtgacc gtgagtcgct
    13801 attagaattt tcttcatatg gttaattcct ttctttctgt tcacttttat ataagcaatt
    13861 cctgtgccaa cttttaaaaa cattggttta atcacgttaa ttcacattaa aaaaagtgtc
    13921 taacctaaaa aaaacagatt agacactttt ttagacactt tatttttgaa tatacggtcc
    13981 taataattca tagagcagcg aaagctcata agcattgact ttaaaattat atttcatctc
    14041 cattgattga aaaatacttc tagaaacata ataaaattca tcttcatctg gtttcaaatc
    14101 ataattcggt tcttcagatt tttctgtccg agccaagaat aaacgttcca tcatcaatgc
    14161 cgtatgcata tagagattta gttttacacg gccatttaaa gtgaaatgat agtaattttc
    14221 atatttagaa atgactgttt ccacttcact catcacgatc gttgggttca gaaagttcaa
    14281 acggtccgca attccttcca acgaaaagaa ttttactagc tcctgaatca agcggttaaa
    14341 ttctgccggc ttcatttcag gactcaaaat atgctccaaa ttggctgctc catcaccgtc
    14401 taagatgtca taaacattaa tattaggaat tgaaaaggta cgtggaagat ccgaagtcgt
    14461 gatgaccaat tttgtcttgt caaaataagt ttcatcattt tggtcgatta attcacgtag
    14521 ttctctgtag tccttcgtga aaacttcgat ggattcatcc gataaatgat gacgaaaaac
    14581 atctttcaat ttgtccgaaa tccccaaacc cgacatacag gaaatgataa tgttgctact
    14641 ttgagaaaag ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc
    14701 aatctgttta aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt
    14761 cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat
    14821 ttgatttaaa gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt
    14881 cacgaaattc cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa
    14941 cgcttcaaaa acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt
    15001 actatctccg tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga
    15061 taaagtcacg acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa
    15121 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
    15181 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
    15241 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
    15301 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
    15361 gtgatgcacc aaatgctgta cttcattctt tatcgaagaa aaattttcat tgaaattacc
    15421 ttcatttatc agctgagtaa ttttttccaa aatcgaatca taatcaaacg gtttgattcg
    15481 atccgttttt atcttttgat ttttctttat caataaacta gcaatcggca agctttctac
    15541 ttcggattcc agcatattta actgaatcaa gatctcattt ttcccaatcg ttaatggttc
    15601 ttcttgtgtt cgactataca catccgcaca actgatttta atgatattct tcagcttacc
    15661 aatattccca ctaaagggat gagataacat taaagacaag gcttctcttg aaacaataat
    15721 atctttttgt aaaacatccg cttcattttg aaaaaataat tgaatcagct ctaatcgttc
    15781 tcgaatgggg cgatcttcaa aagttggcaa cataacacta atttgaatac gccgatcaaa
    15841 ggtgtctaat aaataatttt cacctttttc cgtcgtggcg aaaataaaac gaaccttagc
    15901 agaatgccaa tttacatttt caccgactgg acgatagttt ccagtatcaa taaatagaaa
    15961 gagcttttct tgattttctt tcgataggcg atggacctca tcgagaaaaa gatagccgtt
    16021 gttggccgtt gccaataaac catcggtatc cttttcagcc cccgtaaagg cccccttctt
    16081 gtatccaaac agtgttgccg aaagcagttc gggattgtcc gcataatcgg cacagtttaa
    16141 gatagcaaat ggtgcatctt tttcaataat ttgctcatgg atagcgtatt caaaaatttt
    16201 tgtggctaaa aaactttttc caacacccgt ggctccattt attaatacac tgagtccgtt
    16261 aggcggatat ttgacagcgg ctatacattt ttgaatgacc tctctcagac ttccgtcatg
    16321 accaactaca gaatgaaagg cttcgtttat ttgctccgta ttatctacaa ccgcatattc
    16381 atctaaaggc ttccacaaaa caggctttcc cggtaatttc tcgacctttt tatcttccac
    16441 taatctcgtc aaataatggc tggcattctg acgagagata cctagattct tcgaaatttt
    16501 ctcggcagtg acagaagaca tattccctgt tagtcgtatc agctcatcaa aaactcgatc
    16561 tttagcgctc tttttcattt tttcctccag tttaatgtgt ctaaaagcat aataaactat
    16621 cggctgcaat atgtctattc tatatttgta ttccaatttt tactttgaaa cacaaatagt
    16681 cgaatatttg cctcagatat ctgacaaaat aatttatcta ccaatttagt ttttatctaa
    16741 tatgattttt atgttttttc atagctacaa atattgaact ggattcatat attagtttta
    16801 ttaatagatt acagaagggt taagtatatt tgcatagttt ccaattactt tatccttctg
    16861 taactttttc aatcttagat ttactagccc gtctcgggcc ctattttaca atggttttgt
    16921 ccacttttct ctggtagaaa aacgtggtag aaaaaataaa ataacacaaa aaaagcggcg
    16981 tttcatccgc ttttggtaga agattggaaa actcagatag aaaaaggacg atttttagct
    17041 ctttagaacg ttgataagtc cccattctta ctgagttttg ccattatctc ctatacatct
    17101 tgaattctaa gaataggtca ttatagatgc ctaggtattt cgatcctaga tctttgtaga
    17161 cttcaagatg ggagatcgtg tcatcagatg gatagaattg ttcgtccgac gaaatgtctt
    17221 ttggcaataa cgcttttgct tcttcatttg gtgtagaata accaatatac tctgcatttt
    17281 gtgccgcatt ttccggttct agcataaagt tgatgaaatc ataggcacct tctttatttt
    17341 tcacggtttt tggcataacg atattatcaa accaaagatt ggatccttct ggtgggatca
    17401 cataatgtaa atgttcattt tcccacatca tatcggcagc ttcgccagaa aatgtcactg
    17461 ccacggaggc ttcttcattg atcatataca ttttgatctc atctgccacg attgctttga
    17521 catttggtgt taaatgattc aatttatttg ctgcttctgt cagctgtgcc atattcttac
    17581 tattcaaaga atagcctaaa ctattcaaag aaagccccat aacttctcgt gcaccgtcaa
    17641 tcagcatcaa actgtctttt aattccggct tccacaaatc atcccaatgc ttaatttgat
    17701 ttgcatcaaa gaatttatcg ttatatacga tccctaaagt tccccaaaaa tatggaatcg
    17761 aatactgatt atctggatca aaatccaagt ctaaaaatcg tggatcaata ttatttaatc
    17821 ctttgatctt cgaatgatct aatggaagta ctagtttttc tttgatcatt ttttggatca
    17881 tatattcact tggtatagcg atgtcgtagt ttgtcccacc ttgctggatt tttgtgaaca
    17941 tcgcttcatt agaatcaaat gtttcataat tcactttgta tccatattct ttttcaaatt
    18001 tcgtgatcaa actaggatcg atataatctc cccagttata gatggtaagt acctttgctc
    18061 cactcatgcc acttgttttt tcaagttgac gaacaccaag cagcagcacc gcaataatga
    18121 tgagaatacc taaaaacaga gattgtaatt ttttcatcgc agccgtgcca ccccctcgcg
    18181 tactcttctg tttttcttca gccgttttgg acggttttct ttactaataa agtagtatcc
    18241 aatgaccaat atcatggaga acaagaaaac taacgcactt agcgcattga tttctaaact
    18301 gattccttgt cttgcacgag aatagatctc tactgagagc gtcgtaaagc catttcctgt
    18361 gacgaaaaat gtaaccgcaa aatcatcaag agaataggta aatgccataa aatatccagc
    18421 tatgattcct ggagaaagat aaggcaaaat gatatttttg actacttgga aattattagc
    18481 accaaggtct ctagccgcat cgaccattga atcgttcatt tcctgcaatt ttggcaagac
    18541 catcaagacg acgattggaa tgctgaaagc aatatgggaa agcaatacac tctgaaaacc
    18601 taatccgaat cctagtagtg taaagaaaat caagaaacta gcaccgataa taacatcagg
    18661 agagactaat aagatgttat tcatgctcaa caacgctgtc cgtgcacgtc gttttttcgt
    18721 gtaatagatt cccatagccc caaatgtccc gatgatcgtg gcgatcaatg cagataagaa
    18781 agccagcatg aacgtattca atacgataat gatcaaacgt gtatcttcaa aaacagcttc
    18841 ataattttcc caagtaaatc ctgtaaagct gttcatcgtt cctccttcat tgaaggaata
    18901 aaaaatcaga tagaagatcg gtgcatatag gaataaaaag acgatcccta aataaagata
    18961 cgaccattta aattttttca tttatgagcg acctcctttt ttcttctcgc ctgtcaggag
    19021 catcacgatg aacatagcaa tgattaaaat cacaccgatt gtagaaccca tcccccagtt
    19081 ttgtgtaacc aagaaatgct gttcgatagc cgttcctaaa gtgatcaccc gatttccgcc
    19141 aatcagacga gtcagcatga ataaagaaag agaaggaata aatactgctt ggacaccact
    19201 tttcacacca tttaatgata acggaaaaat cactcgtcgg aaggtctcaa agctattcgc
    19261 gcctaaatct ctactagcac tgatcaaaga aggattcatc tcttccaatg cattgaaaat
    19321 tggcataatc ataaatggaa tctcgatata cgttgccacg aacagaaaac tgaagtctgt
    19381 gaataatatc tgtttcggcc cgatcccgat aaaatcaaag aaatgattca cgctgccgtg
    19441 cacactgaaa atcccaataa atgcgtaagc tttaagcagc agattcaccc atgtaggcaa
    19501 aataatcagc atcagccata attgcttgtg cttcagtttt gttaaaaaat aagcagtcgg
    19561 gtaactgatg atcagcgtga aaaacgtgat caaaaatgca taccatacag aattgatcgt
    19621 catagaaagc gatgtccccg acgtaaaata agatagataa ttattcagcg tgaattgccc
    19681 attcatatca aaaaaagatt gataaatgat cattaataca ggcgcgatca cgaataaacc
    19741 gagccacaaa atataaggga cggaatagat cctgcgcatt gttttcattc ttgtcccccc
    19801 tattcttcgt agctgtcaag acgtgcatcg aattcttctt cagactcgtt gaaacgcatg
    19861 acatggatat cttctggctc aaaggccaat cctactttgc ttccttcttt agcttttttc
    19921 gttgaatgga ccatccattc attttgctgt tcatcataac agatgatttc ataatggaca
    19981 ccacgaaaca gctgagtatc gaccgttacg actagttttc ctttatctgg tgtcgtgatc
    20041 gtcaaatcct ctgggcgtaa aacaacttca actggttcat ttagacgcat cccgccatcg
    20101 acacattcaa attgcttacc aacaaactca actagattat cttcgatcat tacaccgtcc
    20161 acgatattgc tctccccaac aaaatcagca acgaaatgat tgattggctc atcataaata
    20221 tctacgggtg taccactttg gacgattttc cctttattca tgacaaaaat ctcatcactc
    20281 attgccaacg cttcttcttg gtcatgagta acaaaaataa acgtgattcc taatcgttgt
    20341 tgcagatccc gcagttcata ctgcatatct gtacgtagtt tcaaatcaag cgccgataac
    20401 ggttcatcta atagcaatac tttcggttca tttacaattg ctcgtgcaat cgctacacgc
    20461 tgtctttgac caccagacat ttcactaatc tcccgttttt cgtatccagg aagctggacc
    20521 atacgcaaag catcttttac cttcttttcg atatctgatt tggacatttt cttgatcttc
    20581 aatccaaaag caacgttatc aaaaacattc atatgaggaa aaagtgcata atcttggaag
    20641 actgtattta cttgtcgctt attagctggc aaatcattca accgtttccc ttcaaaatag
    20701 atgtcccctt ctgtagcttc ggtgaatcca gctataatac gtaggatcgt tgttttacca
    20761 cagccggaag gaccaagcag tgtataaaat tttccttgtt cgatctcaaa acttactttt
    20821 tttaatactg tttcatcatc atagcgtttc actacttgat caaatgaaat gattggtttc
    20881 cccacgtttt taccccctat attacaaata tgattgcgtt gcaacaatca atacttttgt
    20941 tcgttttttg agatgattcc ttaattgatg ttgttttgtc gcttgataat agatcgactg
    21001 tcctgctttt gccacataga ccgtctctcc taagcttaac tctaattccc cttctaatac
    21061 aaaaataaac gtttcagata atgaaggttc aaacgtctta tattctcctg caccttcaaa
    21121 agtcagcaag acaggctcca tttctttttc attcgaatca gccacgagcc attccaattc
    21181 atacccgttt tcttcatcga aataaaccgt atgatcttct tttgaataaa ccacttgcag
    21241 attcgctgct tcttgatgaa aaaattcttc tggagtcaca cctaagactt caagaataga
    21301 aaagaatgtt tccattgatg gtgaacttaa atctcgttcc aactgggaaa tatacccttt
    21361 tgacaaatct gtgcgttcgc ctagttcttc ttgtgtcaaa ttcttttgga tgcgcaaatt
    21421 tcttaacttc tcaccaattt ccataatttc ctccgaatcg aagttttcta atagtaaact
    21481 tcctgtttac taccactcgt attagtatac gaaatttatt gaaaaaggca accctttgta
    21541 aaattttttt tgctgaatat ttctttatct tttggaataa attctagttg tttgattctt
    21601 tatttttcac ctaatttttg tctaaattta cggaagaaca agaataaaag agtaggcttt
    21661 atggtatgat aaaagaaaat tttaaaagga gtgtctcacg aatgaacgct tttcgatctt
    21721 ttcaggtaat aaaggaacct gttttccata cagcaatcag tgatctgcca tttactgagt
    21781 tggctgaaaa tgaagtcttg gtaaaaattg cctattctga tgtcaattat aaagatgcat
    21841 tggcaatgag cgagtctggt caggtgatac gaacatatcc gatgactcca gggattgatt
    21901 tatccggaac tgtcgtccaa agtaacaatc cacgtttttc aaaagaagat cttgtacttg
    21961 ctactggttt tgggcttggc gtcacccatc caggcggtta tagccaatat caaaaagtac
    22021 caggagactg gttagttcct ctaccaaaaa atatgacgct gcgtcaagcg atgatccttg
    22081 gtacagcagg gtttactgct atgttgtgtg tgaacgcttt aatccgtcaa ggtatgacct
    22141 ccgataaaaa agttgtcgtt actggtgctt ctggcggtgt aggcagtaca gcgatagccc
    22201 tgttacataa actaggattc cagtcaatca ttgccttttc cagaaaagaa gagtctgtca
    22261 catggctaaa aagtctaggt gctttgcaag tcgtacgacc tgatgaattt ctgccagaga
    22321 caacaaaagc tttaggaaaa cagcaaatcg actatgtcat cgacacagta ggtggcgagc
    22381 agctaagcag tcttcttcca ttgatctctt ataacggtgc agtagcttta tgtggcaatg
    22441 ctgggggaat caaactaaac gcgactgtct tgccttttat tctgcgaaac atccagttga
    22501 ttggaattga ttctgtcaat gtaccaatag atcaacgtct ttctttatgg caacagatgg
    22561 cggatttgca gattgcagat gaactggtcg tccaagagat tactctggat caattgcctg
    22621 aaacagcatc taaactactt gctggaacac accaaggaag aacactagta aatgtaggtg
    22681 accataaatg aagattctaa tcacagctgg aggaacgact gaaaaaatcg atcaagtacg
    22741 tgctattaca aatcattcga caggacgatt agggcaagca ttagctgatt atttagctgc
    22801 caatccggat accacaatcg attacgtgac tacgaaacaa gcactgaaac cgaaaagaca
    22861 ctccaatata acgatttata cgatcgaatc tgcactggac ttatttttac aattagaaga
    22921 actaacgaaa aaagaacact acgatgcgat tatccacagt atggcagtca gtgattttac
    22981 tcctgctttt agtttttcag aagaacagct ggcaaaaaac ctacccactt cttcaacgca
    23041 agaagaactg gacaattggt ttgcggaaaa tgaacagaca gataccactg tttcaaagat
    23101 ctcttctaac accgagcatc ttgtgctcgt tttgaagaaa acaccaaaaa tcatttctta
    23161 tctacgtgaa tggcagccaa aagcaaaaat cattggtttc aaactattag tagatgtacc
    23221 aaaggaatct cttctggcag tcgcaaaaaa tagtctgata aataacaaaa ctgattttat
    23281 tttcgcaaat gatttgacgg aaatccatgg cgagacacac cacggctatc tcttatctaa
    23341 agatggaaca gtggaagaag ctcaaagtaa atctgagatt gctgcattga ttactgagaa
    23401 aattagactg gaggaatcaa aatgaaaaag atcttactag gcgttactgg aagtatttct
    23461 gcttacaaaa gcgctgatct tacaagtcaa ttcgtcaaat taggtgccca ggtagatgtg
    23521 attatgtcta aaagcagcac acattttatc acgccattaa ccttgcaatc tctgtcgaag
    23581 cgcgcagtcc atacagacgt catgcaagaa tcaaatccgc aggtaatcaa tcatatcgaa
    23641 ctagcaaaac aagctgactt gtttctcatc gcgcctgcta cagcaaacat tatcggcaag
    23701 ctagcaaacg gcattgcaga cgatcttctt tcaacagtcg caatggcgct tccagtggga
    23761 acaccaaaat tgattgcccc tgccatgaac acgaatatgt atcaaaaccc gatcactcag
    23821 cgtaatctgg aaacattgag atctgtcggc tatcaggaaa ttgaaccaag agaatctctt
    23881 ttagcttgtg gagattttgg aaaaggtgcc ttagctgata ttcagacgat catcgaacag
    23941 gtcatgctga ctcttaatga aagaaatgct tagaaaaaag gagtacttat gaaaaataca
    24001 aaaaacttta cattaactgc gatgttttta gctattttga ttttattagc tgttacgcct
    24061 ttaggtttta tccctatcgg tccaatcaat gcaacaacca tgcatattcc tgtaatcatt
    24121 gcttcgatcg ttttaggacc aagactaggt gcttttcttg gcggtacatt tggactgatc
    24181 agcatgatcc gtagcacagt tatccaaaca cctttgtctt ttgtcttttc tccgtttatc
    24241 ccagtcatcg gaacagaaca tggaagctgg aaagccttgc tgatcgcgtt tattcctcgc
    24301 atcttgattg gggtggttcc ttatttcgtt tataaaggtc tgcgcaaact aatgaaacaa
    24361 aaagcagatt ccgtttcttt attcttagct ggactttccg gttcattgac caatacgatt
    24421 ttagtgatga atatgatcta ctttttattc cagcaagatt atgccaaagt catcggaaca
    24481 aatttaaatg ctgtttattc agctattcta gcggttattt ttacaagtgg tatacctgaa
    24541 ggaatcgtcg caggtcttgc gactgcagca gtatgcaatg tcttgttaag atacttcaag
    24601 cacccttctc ttactaactg atagtcatcg tagccgatct ctgatttttt tctcttttgg
    24661 tgttactatt gaatggaaag atttgacgtc gaaaggatga tccaaatgaa aatttttgtt
    24721 gtaggtgcaa acggacaaat tggccgacac ctgataaaag atttagctcc aagttcccat
    24781 gaaatttttg caggggtgag agatgttgct tcccaaacat tagtaaaaaa agagaatgtt
    24841 tcgtatgtct cttttgattt aacttggtcc gtggaaaaaa tgaccgaagc attcaaaggc
    24901 atcgatgtat tgatttttgc tgccggctct caaggaaaga atcttctgca agtagacttg
    24961 gatggcgcaa tcaaaacagt gatcgcagct gaaaatgcgc atgtctctcg ctatctgatg
    25021 gtcagtgctg tttatgcaga tgaaccagca aaatggcctg agtccatgac agattattat
    25081 attactaaac attatgcaga tgaatggctg aaacgaacta acttagattt tgtcattctt
    25141 caaccagtca cattgactaa cgatgaagaa gttacttcca ttcaattaac taagcctaat
    25201 gagaaggcat caaaaacgat cactcgctct acagttgctg ctgtacttgc cgctctagtg
    25261 gaagaaacgg atatttctcg tacgactcta gtactttctg aaggtagcaa agagttgaat
    25321 acagcattcc aagaatgggc aaaggaggaa tagatccatg cgtgccattt caatcaagca
    25381 tcctggttct gtagatgtat tagaacaaat tgaagtgcct gttcctaaac caaaacaagg
    25441 cgaattactg atcaaagtcc atacagcagc tgtcaatcga acagatatta tgaaaagaga
    25501 atcagtctct ttgaaacctc cctaccctat tttgggagtc gaagtagctg gagaggtagt
    25561 tgagaataaa agtgatatct ccacttttac tcctgggaca aaagtatacg gattagtcaa
    25621 tctaggtggt tatgccgaat atgctgtgat gcctgccgat cgtgcaatcc ttctccctga
    25681 tacgctagac tatgtttctg ctgctggaat ctcagaagtt tttttgactg cttatcaaac
    25741 actttactgg cttggaaaat tacaagaagg cgaaactgtc ttgatccatg caggagcaag
    25801 tggtgtggga acagcagcga tccaattagc tagacagctt tctcacgcga aaatcatcgt
    25861 tactgcagga tcagaagaaa aactcgcctt ttgtaaagaa cttggtgcag atgaattgat
    25921 caactataaa aaacaagact ttcaagaaga ggtacgaaaa atcactgaag gtcggggagt
    25981 cgatgttatt ttggatttca tcggcgcttc ttactgggaa aagaatttag cttctatagc
    26041 cgttgatgga cgttgggtct tgattggtat gctaggtggg accatcgtgc ctgagataga
    26101 ccttggtgta ttgattggga aacgtgtcca actgcttggt acattattga cacctagaag
    26161 tgatcagtat aaagcagagc tcgcacaaac ttttatgcaa aaagctgggc cttttctaga
    26221 aaatggcaag attcggccaa tcattgaccg tacattccaa ttcagcgcag tcaaacaagc
    26281 gcatgaatat atggaagcaa acaaaaacat cggaaaaatc attttgaaga taactgaata
    26341 aaatcatgct gatcaaaaaa gaggctggga cagaagcgtt taactccaag aaataagaag
    26401 aaattcacga aaattgcttt tcaaattttt gtgaatttca gcttatttcc gaaggaattt
    26461 cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc tttacttttg
    26521 tcccacgctc tttttccgaa taaacggtgt tcaaaagctt gcatctgcgg taataagtcc
    26581 aaccaagtta aaaacataag aagctgtttt tacttggctg ttcttattac ttgatgcagg
    26641 gcagcttttt cacaacctct tcactaaaca gtgttcaatc agctgaccct cggtattagc
    26701 tcaaaacgct gatttcacaa cctcttttta tttacgttct atttcattca ttttccgaag
    26761 caaatcgagc tgcttgtatg cccgcttgtc gcccaaaaat aatgatctcc gcaactgaat
    26821 ttccaccgat ccggttgttt ccatgtaagc cacctgtgac ttcaccagca gcatataacc
    26881 ccctaattgg ctggttttct ttatctaata cttcagtgtt cgtattgatt ttcacaccgc
    26941 ccatcgtgta atggattcct ggtgcgattt tgatcgcata ataattcgga gacgataagt
    27001 catgttccat ggctgtggca cggttgaatt gagcatcttt tttctccgca acatccgtat
    27061 tccatccatc aactgttttt gctagtgttt cttttggtaa atcgattttt tctgctaatt
    27121 cttccattgt ctttccagtt gtgacatatc ctttttggtc ataaaattca atagctgtgg
    27181 cacgatcacg cacgccttgg tcaaaaatca aataagctga tttttcaggc aatgctgtaa
    27241 ttgctgcaga tactttatcc cttgtatcca tttcattgac aaatcttttc ccctcttgat
    27301 cgaccaagat tgctccttct ccgcgaacaa cctcaccaat caagaccccc tcatcctgct
    27361 gcacagttgg atgaatttgt attttatcca tatcaacggt ttgtccacct aatttttcaa
    27421 tcatggtgat accatctcca gttgatcctt cttgatttgt cgtaatataa tcagctaaat
    27481 cgggacgata tttttcaata aattctttgc tggcaccaaa accgcctgtg gtaactacga
    27541 ttgcttttcc ggtgacctct tttggttctt ctccttgaac atgtacagtc acttcattga
    27601 ccgtttcccc atttttctta atgtctgtca catctgcgtt gacaaaaata gggatttccc
    27661 gctcatggac gttattcaat aacccctcca ctaagtatcc accaatagcc gagccatcag
    27721 acggacgatg tgtcctcttt tcactcatcc ctccagtgat cgttaagttg tccagtttga
    27781 taccgttttg atctagccaa tcgaccgcat cagcagagtg atcgacaaag tatcgaagca
    27841 tttctttatc attcgttcct ccaccacctt ttagcgtttc ttcatagaag gcatcattcg
    27901 agtctttgat tccttcttct ttttgaaatt ttgtttctga agcattcata ccgcttgatg
    27961 atttagatgt gtttcctccg gcaacaggca tcttttccaa aattactgga ttcaacccag
    28021 catcttttgc ttcgatagct gctgccatcc ctgcaccacc agctccaata atcacgacat
    28081 cataagattc tttcatttct tttggatctg tatatacttg ttcagaagcg cctgatgata
    28141 cttcggcaga ttccttcgta ctagaacttg tctgcgctgt atttttctga tctgcgccgc
    28201 atgcgctcat agcaagaagt gcaacggctg ttaataaacc agcaactaat tttttcattt
    28261 gtatccccct tttctcctta tactatatta agtgattttt ttcacaatat caactctgtt
    28321 tttctttaag tcatatagct ttggtaaaca cacgcttctt agtataatta aggatataca
    28381 tgaaggagtt attttatgaa tcatttgaaa acctttttta cgaacagtac aaaaactgca
    28441 ggtagaatca caaacggaat ctatatttta ttacgtatca tcgtcgttat tatgctagtg
    28501 gatcaggtct ggaaccaaca ctggggaaat acaatgcttt tattactgac attaatttta
    28561 tttgaaatcc cttattttct ggaaaagata ttaaagatac agattccaaa tatgctagaa
    28621 atcattttgt tatcttttat ttttagttca acagttttag gagagttaag tgatttttat
    28681 ggctattttt caatgtggga tacttttcta catgcattca gcggattttt agctgggggt
    28741 gtcggctttt cccttgttta tttgctcaat aaaaatacaa aaaccatgaa cttgactcct
    28801 ttattactag cagttgtttc cttctgtttt tcgatgacag ttggtgttat gtgggtgttt
    28861 gtggaatttt cagcagataa attactgcaa ttcgatatgc aaaaagatac gatcatccag
    28921 caaatcaata gtgtggagtt aagtaaagac ggaaacactg tctatcatgt tccagatatc
    28981 actcggacaa tcattgaaag tcaaaatgca gatggtaaaa cagataaaac aatcatccaa
    29041 aatggttact tagacgtggg aatcatggat actatgaagg atttatttgt taattttatt
    29101 ggagcagttg ttttcagtgt atttggttac ctctatagtc gaaacgatta ccaaaaattt
    29161 acgttcatca agaattttat tcctaaaaaa atcaaacgat aaaacatgct aaaaaacaag
    29221 agaaggggca gtgacaatac ttttgtcact gccccttctt ttttgaatgt atggcatgcc
    29281 attagttatc cgatagtatt aactcaaaaa agtaagatat gaggaatgac tatttcgttt
    29341 tttatcccaa tactgaggac ttatttcacc atttcgttat ttatctaatt tacttaaaac
    29401 ctgcataact ttttcataat ctggattagg tgtgccgtct agattttcag caataaaagt
    29461 aaaacccatt tttttataaa gagcaatcgc ctgatggctc catgtctgtg tgtgaagata
    29521 gattggtccg tccgtatgga gggtaggaaa ttcttgcaag actctggcag tcaatgcttt
    29581 tgcgagccct tttccttggt aatctgattt cactgctaac caatgaaaaa ccggatacac
    29641 ttgctctctt gatttttttc gccaagcggt acaggttgct actttttctc ctttttttgt
    29701 ctctacaaaa aacatccttc tttcaagttc ttcaggataa ggagcaaagt tttgttgaaa
    29761 atactcaagt gcttcatctg tcgtttgaaa ttccccaacg gaagtctcaa tctccgccca
    29821 agcagattca tcttcttttt gataaaatcg aaattcaaaa ccttccgcta aaggcgtgat
    29881 tggaacattt tgttgaagtg gtcttgtcat ccagatttct gcgtaaggta acgttttatc
    29941 taacattttt ctatccctcc tcgtctccat tatgccaaat aacatatgac tcagctactt
    30001 atttgactat aacagataga gatataaatc agaaccagtc atctgcgtca aattcatttc
    30061 gattagcgta tacccatgtt cctgccatac ctcgcatgaa atctcctaaa gcagaagaag
    30121 gaatacctcc accaggtgcg ggtgttcccg gactaggaag tggtacttgc ggctgcagat
    30181 gctcatcggt ggaatcaata gttgacaagc gttttttctt cgtttccttc tggtcatctg
    30241 attccttctg atcttccgac tgtttagcaa caaattcttt ttctgattgt tgttttattt
    30301 taggctctaa aatttcattt tccaatccag aaacttgtgg ggccaaatga gcttcttgcc
    30361 ttatcgtttt attagattct gagatttttc tagatattct tgctaactct aggcttcttg
    30421 tttgttttac tttccctgtt ggagaaactg catgagccat ttgttgtttt ttttctgaca
    30481 agctttcttc ttgtcttttt tgttcttttt gatctatctg tttgtttaat ggtaaaacat
    30541 gtaatagtga ctgagcatgg agttcttgga gtgaatacgg gtcatgataa ctatacataa
    30601 tcgtaaaatc acctgtttgt ttggtcaaat aaccatcctc caatggtact tcattgattg
    30661 taaccgatac atcctttaac ggtacgggtt tacctaagga atttgttgct gattggatca
    30721 actcttcttt gtttattttt tcgtttggat gaacaataag atcatgacct tctaatgaac
    30781 gattgtctgg tatataaaca taagtaaagg taatttcccc tcctgattgc ttcctattat
    30841 tcatcagttc tgagtgaagt acttcaagga tctccgacca gtgacttttt ctgtctaatc
    30901 cgtttgcttg catccaatca gaaatagaag tgactttccc attttgttca taagtcgata
    30961 aatctatatt tggcactcga tcagaaaatt cagcaggtag gcgcaaatca ggaatacgat
    31021 ttacactact catatgtgtt tctgcttgaa gttctttatt tgtttgacta tctataaaat
    31081 gagtgatgac agtcgatgaa gcagcagatg cttctacata aactacagct gttgtttctg
    31141 ccacatttga tgttttcgag tctatataag ttaatacaac gggatattct cccggagttg
    31201 tagtatctac tgtcccgttc attttgattt cttctttatt tcctgaagtt ccatcgcttt
    31261 ttgttacata ttcaacaaga tctttagggg cgtaactctc tcctgttctt aagtgaagat
    31321 cttttccttt gatagctgtt tgatcagcac gaacatggat cacagcagat gcagtcattg
    31381 tttttaaagc aattggatca aaataggaca aggaaatagt agatgttcct gtattagtcg
    31441 tatccacgat attcccattg tttgaaatta ctttggacat atctccttgt gttccatctg
    31501 cgttcttcag cctttctacc agatcagata tcgaaacttt tgtccctgcc agaacatcga
    31561 ttttctttct ttcaaactgt gaataatctt tttcatatac ataagaaact tgtgcgcttc
    31621 caccgtcctt tatatctgtc aaagcatgat tcaaaatatc agtgatctgt tttaactgat
    31681 caccttttgt aggatcagtc atatcggaaa agatagaaag cggcacactg cttccggttt
    31741 ccgatgtcca taatgttttg ttaggaatta accagtagtg gtttatcgtt ggaggataac
    31801 tgactttatt ataggaagtc aatgcaggaa gtagctgttt tccatttgca tcagtgaaag
    31861 tatgagtaat agtgataggg gaatcagtgg tctcagaaac agaggtacgt acgaccttga
    31921 tggtttgtgt cgttgcctga acgggtacat gcatatagac acctacagat aaactgatca
    31981 gcatcgtgcg catcataaac ttaacgtagt gtttttcaga acacgaccgt tccttatcta
    32041 aacgacaagc gtgtttattt agttgttttg aacgtctttt tgaacacatt tattcttagt
    32101 cctccctact cttgtctaaa catgaagtag taattttcat aagatgattt cattatataa
    32161 ataaaatcaa aagaagatgg actattagga gagtattttt tttgattttt tattgtttca
    32221 agaaaatcgg aataataact tatgtacttt ttaattttgt taagtaatat atctagttat
    32281 atctagttat atctagttac cttttctttg aaaaaaacat aaatcagcta ataaatatgt
    32341 gagacaaagc tgccatccat aaatactagc tgattttttc agttaaatgt ctattttttt
    32401 ctctgatgat ggtatttcca aaatattccc agtcatctgg agtcggtgga tttttccaaa
    32461 ttatctgttc tttattaaat ttttcaagta aacaatcaga taaataaata ttcgtacgag
    32521 aagtgattcg actctcaatc acaatattgt aatttttaaa tcctttcact tgagaaataa
    32581 tgtaatcggt ataagcagat ccttgcgaaa aatcaataca gacatgaatc ggtgcttcaa
    32641 aatatgatac cggacaaata ccgaccaata aaaagagata atcataaaat aagcgaatca
    32701 tgaaacgttc atcttttccc aagaaatagc gtttattctc ttgtatgacc ttttggattg
    32761 ctgtactgaa tattggatac gtctcgaaga aaaactgtag ctgcttttta gacgtaaagc
    32821 tagtcatctc aaagtcgaat atccaatttt ttcgattgac atgcatcata cccatacgaa
    32881 gttcttttcg tatatatagt ctttcttctt cagagatttc aatcgaaaat ggtaattgat
    32941 caatcaattc cactgacatt ttttgactaa tcatgtggat atcatgaaaa tgagcttccg
    33001 caagtccaaa tgcgccatct aattcaaatt cttcttccgt gatcaaaaac aacatgatat
    33061 aagaaatctc atcaatgatc tgctctttag ggatatgaag aaaagaaata tgtgataaat
    33121 ccttgatgat cttcattcct tctgagctct taaagtattc atctgaaaag aaacgttttc
    33181 cgattggttg attcccatag gccctcaaca aactaatagt ggttagcaaa ttgaatttga
    33241 ttcgttttgt tgcagacagt tttaaattga acagatattc aaaatattgc acgatactct
    33301 ttgcttcatt catgacgctt tctctaaatg gcatagaaaa accattaaag accccgaaat
    33361 ataccccaaa taatacgttc cgtatgttta tttcttcccc aactaatatg tttttcttta
    33421 actttatttg atgctgttca agaaaagaga ctaattctct tctttttaca taggctcttg
    33481 atatgcttaa aaaatgattc tctgcaaatt tttcgatcgt tacttttgaa tccacgatct
    33541 ccgttaacag tcgagcaatt tttgatcgtt gaaagtagat tcttcttaaa tttttgatat
    33601 ccgtcaaatt cagacgttcg acatggatct ctgcttcttc tgaaatttgg atctctggct
    33661 ttgttttgaa ttcagtaaat tctttattta attctatgat ataatttctt gttttaaatt
    33721 tagacaaacc taatgtttca tataacttag gcagcactac ataattcttt ttctcaaatt
    33781 ctaaatatct agctagcagc agtttttctc tatcttcctc ttctataagg taatccaact
    33841 tcatatccta cacctcaaaa aatgcctcat accaattact tgatatgcag atgaaagttc
    33901 atcttttcac ctatactgat tttatgatgg attatgcttg ttttttcatc agttattctc
    33961 attttttatc ttttttttga gaatattgca aaaaatggaa aaatttatga ggaaatattc
    34021 tatatttttt gttttattgt gttaaaatgt acaagatttg cgccatttgc gtaaacaacc
    34081 acaaaaaaga gcaggacggc caccgtcctg ctcttttact tattttaagt tccattactt
    34141 attaattggc taaacttctg cttgtttctg atattgcttg tttttctcca atgatccgca
    34201 cttctgtttc taaagacaca tcaaattttt ctttgattac ttcttggatg tgcgcaatca
    34261 attcaatata atctgtcgct gtcgcatgat cgatattgac gatgaatcca gcatgttttt
    34321 cagagacttg tgcaccgccc catttcaggc cttgcaatcc tgcttgttgg atcagctgac
    34381 ctgtatagtg tcctactggg cgcttaaaga cacttccgca tgaagggtat tctaatggct
    34441 gttttgattg acgcaattcg gtcaactcat ccattcttgc tttgattgct tcataatccc
    34501 ctgtttgcaa actgaatcga gcttccaata cgatagcacg taattcttgg actttactgt
    34561 gacgataaga aaataccatt tcgtcttttg tcaaagtttt caatgttcca tcttcaagca
    34621 aaagatccac ttcagcaaaa acatctttga tctctccgcc atacgcacct gcattcatat
    34681 aaaccgctcc accgacactt cccgggatgc cgcaagcaaa ttcaaatcca gtcaatgatt
    34741 ctgccaaagc tgcataagtc gtatcaatca gtgaggcacc tgcttccgca atgaccatcg
    34801 ttcctttgac atgaatctgt ttcatttcag tcagcatgat gactacaccg cgaatcccgc
    34861 catcttgaac gatcagattg cttgcatttc ctaataccat ccaaggtata tcatggattc
    34921 ggcaataatc gatgatttgc tttacttctt cttgtttttt cgggaatgca aggacatcag
    34981 ctggtccacc tgttttcgta aacgtatagt tcatcaatgg ttcatcaaac aatatagtaa
    35041 tcgtggctaa gctttcaact atttcttctt tattcactga ggattttcct ttcttttctc
    35101 aaacgtcctc attattctat cacgcttaat acaatcttgc cagtcttgtt caaagttgat
    35161 gacggtagtg atctttaagc acttcctcac ataattcatg acttcttaca acttcttttt
    35221 gtttaagcaa ttctgtttcc gatttaccta aacggatctg agaaaagaag gcctctacca
    35281 ttggctcaaa cccgcgtttg actagcgtgt ttgtccagtc gccaaattct ttcacttttt
    35341 ttccatcagc atcttgaatg acaagctggg tcagatcgtt tacttcataa gtaccatttt
    35401 tacttgttac ttgatatttt tctatattag cgccacttgc taaatccatc gttaaaatag
    35461 ccgtttgatt ttgtgtttct aattgtaaaa tggcatattc caaaaattcc tttgtttctc
    35521 ttatctggta ttttgttctc aaaatgggtt catctaataa atacacagct gtatcaataa
    35581 gatgtaaaaa caaatcataa aggacgaact ctgtcgtttc ttttgccgct attcgatttt
    35641 tttgcaggtg gatcaaccgc ttatctggga tacgtttcaa ttcttctacc ataggagcaa
    35701 agcgccggtt gaaaccgatc atcaaaatta tttggttctt atcagctaat tcttgcaatt
    35761 cacgaacttc atttagatgg acactcagtg gtttgtcaat ataaacatgg ataccatttt
    35821 ctagacattt tttggctaat tcataatgta cttttgttgc tgcgtggatc atacatgctt
    35881 cgattttttc ttctaaaagc tcatcgatcg tttcatatag atgttggaac ccgtactctt
    35941 tttgaattct ttcttttgtt tctttatttc ttgttgcaaa ataaaaatca agtgttcctt
    36001 gttttttcgc ataagttggt aaatatgctt tttctgcgat attccctaca ccgattacac
    36061 caatcttcat ctactttcct cctggatcat ttagttactt tcatcttaca ccattttttt
    36121 ctaaaatgag gtacaatagt atcgcaaagg taaggaaatt aattcgaagg agtgtgcttt
    36181 tattgaaatt tatctcttgg aacgtaaacg ggcttcgtgc catcgtaaat aaaaattttt
    36241 tagaagtttt tcatgagtta gacgccgatt ttttctgtct gcaggaaacg aaactccaag
    36301 caggacaaat tgatttagat cttccaggtt attatcaata ttggaattac gcggaacgaa
    36361 aaggctattc cggcacagcg atttttgcta aaaaaccagc attgaatgcc acttacggaa
    36421 tgggtatcga tatccatgat acagaaggcc gtctgattac tttggaatat tccgatttct
    36481 ttcttgtaac ctgttacacg ccaaattctc aaagcgaatt aaaacgttta gattaccgat
    36541 tagaatggga agaagccttt tataattatt tggaaaatct aaaaaaacaa aaaccagtca
    36601 tcgtgtgtgg ggatctaaat gtcgctcatc aaaagattga tttgaaaaac tggaaaacga
    36661 atcaaaaaaa tgctggattc actccagaag aaagagcggc tctttctcga ctgttggata
    36721 acgggtttat cgatacattc cgttattttt atccaaccca ggaaggtgtc tactcttggt
    36781 ggaactaccg attcaattca aggaaaaaca atgctggttg gcggatcgat tactttttga
    36841 cgagcaaaga tttagagcca ggactagctg atgcaaagat ccatacggac attatgggca
    36901 gtgatcattg tccagtagaa ttagatttga aataaagagg ttgtgaaaaa gtcgtttagt
    36961 ttcgagtatt aagaaaaatt ttgtgaaaat ggctttccac attttgcata aatttggcat
    37021 aataccgaga aactggcttt tgaacactgt ttatcgagag attgtgaaaa agctgtcctg
    37081 catcaagtaa taagaacagc caaacaaaaa tagttcctca tatttttcgt ttggttgggc
    37141 ttattaccgc agatacaagc ttttgaacac cgtttattaa gaggttgtga aaaagctgca
    37201 ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatattttt cgtttggttg
    37261 ggcttattac cgcagatgca agcttttgaa caccgtttat taagaggttg tgaaaaagct
    37321 gcactgcatc aagtaataag aacagccaaa caaaaatagt tcctcatatt tttcgtttgg
    37381 ttggacttat taccgcagat gcaagctttt gaacaccgtt tattgagaag ttgtgaaatc
    37441 agcgtcctga cctgagtatt agagaaacaa atggcaaaat agttcctcat attttgctat
    37501 tttttgagct aataccgagg gtcagctgat tgaacaccgt ttagtggaga agttgtgaaa
    37561 aagtcgccta ctttcgagtc gtaagaaatt tttttgaaaa tggttcctca caactttgca
    37621 taaatttgac ttaataccga gaagtcatga tccccatcta actccaaatc acaaggaatg
    37681 agttcaaaaa ctagcttttc tcaacaaata ttacataaaa aattctatgt tttttgttaa
    37741 atttatttgc ttttttcaaa agtatgttac agtaatttcc caaggaggtt ttacagaaat
    37801 gaattttgtt gccatggatt ttgaaactgc caatcatcag ccttatagtg cttgttctct
    37861 tgcgctagtc atggtaaaaa atagccagat cgttgatgaa ttctatacat tgatacagcc
    37921 tgagactcct tttttctggc gaaatgtcca aattcacgga atccatcaag aagacgtacg
    37981 caatgcgccg aaattcccag aagtctggca aactatccaa ccatattttc aaaaaaatcg
    38041 tttagtcgtt gcacataatg ctgcttttga tacaaaggtc ttagcgggat gcttagatta
    38101 ttatcatctt gaacagccta attatctttc tttatgtaca gtgaaaagta gccgtcgcct
    38161 gtttcctgaa tttccaaatc atcgattgaa cactgtgtgc gaaaatttga acatccaatt
    38221 agatcatcac catgatgcat tggaagatag tcgtgcatgt gcggaaatcc tgctttatca
    38281 agaaaaaaaa ttcgggacag atccattgaa aaaacttgtg actataaagt aaaagaatac
    38341 ttatgaaaca cacaaagagg tcgtgagcct gccgtttcac tccgagtcac aaggagcaat
    38401 ttcaaaaaat agcttctcat gtttattaaa tattgtgact ggtgaccgag gagctggcag
    38461 gagaacaccg tttattggag aggttgtgaa aaagctgttc tgcatcaagt aataagaaca
    38521 gccaaacaaa aatagcttct catatttttc atttggttgg acttattacc gcagatgcaa
    38581 gcttttggac accgtttacc aagaggttgt gaaatcagcg ttttgacctg agtattagag
    38641 aaacaaacgg caaaatagtt cctcatattt tgccgttttt tgagctaata ccgaaggtca
    38701 gctgattgaa caccgtttat tcaaaaaaaa tggactgcga cacgactttt gtcacagtcc
    38761 cttcgtgtgt ttttctgcct tctcaaaagg atgacagttt ctcactcttt tcctatttct
    38821 tctattcaat caaataactc attttatata catctaaaaa ttcacctaga tctgttcttg
    38881 cccctctagg catgaccgct tcgatttgga agcccatttt tcggtaaagg tgtacggctc
    38941 tttcattacg aacttgaacg tcaagctcca atcgaaaaag tacacccatt tccttcgccc
    39001 aactgatgat ttcttctagc ataagagtgc ctagtcccat tccccaatat tcctgcagaa
    39061 tactgatacc gacttctccc acgtgagaca aacgaaattg actgtctgcc ttgacagatg
    39121 ctgttccaat aatcgtccct tcatagattg caagcagcaa taaattatta ttgctttcgt
    39181 atatataatc caactcttct tctaaggttt ctggtggtaa caggagttct gcttcatcca
    39241 aaactaaaaa ttctgtctcc ttattaactt gtcccatcat caaaagaatg tcttttgcat
    39301 ctcctggcac tgcttcccgc aagatgatcc caacttcttc actcatgatt ttcagcccat
    39361 ttttctagaa ttcgctgttt gaaggtttca ctttgctccc cgtatgagat tagtttcaca
    39421 taccgctttt ctaaatctgt atcacttttt tctaaaatca gttccaaata atcctccggc
    39481 agtgcttctt ctaatagatt tccccattca acaacggaaa gcccatcacc ttcaaaatat
    39541 tcatctaacc ctaaatctgc tccgctagct gctacccgat aaatatccat atgatacaac
    39601 ggaatccgac cttgactata ttctctaata atcgtgtatg tcggactttt gatcatttgc
    39661 gttatcccta atccttgggc aattcctttc gtcaacgttg ttttacccgc acctagatca
    39721 ccagtcaata tcagattgtc acctggcatt gcggaatgac caattgcctc tgcgaattgt
    39781 tctgtcattg ttaatcctga tagttcgatc atttttcatc ttctcccgct cttctttctt
    39841 tttgccagta tatcgcgtaa tgaagttttt ttaaagaaaa aatgaactag tcaagaacag
    39901 cagctgctgt ttttggctag ttcgcgtgta tttgttaatc aatcaatgtt tgtgctgctg
    39961 tgataatcga taatttatat acatcttctt catttgctcc acgagacaaa tcagaaaccg
    40021 gtttgttcaa gccttgtaga attggtccga ttgcttcaaa gttaccgaaa cgctgagcaa
    40081 ttttatagcc gatatttcct gactgcaatt ctggaaatac aaagactgtt gcttgaccag
    40141 ctacttctga atctggcgct ttcagttgtg caactgaagg aacataagaa gcatcaaatt
    40201 gcaattcgcc gtcgatcatg tattgtggcg ctagtttttt agcgatttta gttgcttcaa
    40261 ctactttgtc tacttctggc gatttcgctg agccttttgt cgagaagctc atcattgcta
    40321 cttttggttc gatatcgaac aattctgctg tttttgcaga atctacggcg atttcagcca
    40381 attcttgcgc agttggattc acgttgatcg cacaatccga aaagacatat ttttcttgat
    40441 ctcttccacg taccatgatc atcgctccgc ttgtccgact gatgccaggc tttgttttga
    40501 tgatctgaag tgctgggcga acagtgtcgc cagtcgaatg gatcgctcca gagaccattc
    40561 cgtctgcaat ccccatatac gtaagcatcg taccaaagta attcacatct tttaaaatct
    40621 tttctgcttg ttctttggat gcctttccat ttctacgttc aacaaaagta tccaccattt
    40681 catcccactt atcgtaatta tcagggctga tgatcgtaaa gctagatgtt ttgattcctc
    40741 tggcatgcgc tgcatttctt atttcttctt cgttccctac taaaatgggt tccacaagtt
    40801 cttctgcttt caaccgggca gctgcgccta aaatacgagc atcagtagct tccgggaaaa
    40861 cgattttgat cccacggcga acaattttaa atcttaaact atcaaacaat tccacaagat
    40921 gacctccaga cgtttttata tgtattatca tacactattc cagaaaaaaa gaacagttta
    40981 ttttatctgt atcagtcaaa aatgctggaa aaattaagtt tttcacatac aaagcgaact
    41041 gcactataac aggaaagcgc tgttttatta cactgtttca ggcagttgcc aatcaatcgg
    41101 ttcttctcct aacgcaagga gcgcatcatt cgttttcgag aagggtttgg aaccaaaaaa
    41161 gccacgactt gcagataacg gactgggatg tggagatgtt atgatgatat ggcgactctt
    41221 atcgatcatt ttgatttttt cttgtgccgg ttttccccac aagataaaca cgattggttt
    41281 ttcccgttca tttaattttt caatgatcgt gtctgttaat ctttcccaac ctttcccgcg
    41341 atgagaatac gcttgccctt cccgaacggt aagaacggtg ttgagtaaaa ggactccctg
    41401 tttagcccat gacactagat ttccatgttg aacaggtgcg attccaagat catcataaag
    41461 ctctttatag atatttctta acgatggcgg gatctttacg ccaggttgca cagaaaaaga
    41521 taagccatga gcttgatttt ctccatgata aggatcttgt cctaaaatca ccactttaac
    41581 ttcttcataa ggagtcaatt ccaatgcttc atagatatga tacatatctg gatggatctt
    41641 ttgggacgca tattcttttt ttaaaaattc tcttagatgc agataataat cttttgaaaa
    41701 ttctgaggac aaaacttctt gccaactgtt atgaatgatt tctttcaaaa actccacctc
    41761 ctaataaaaa gaataactca cattttcttc aatcacaagg gacaatcttc accctcagca
    41821 cttgattaat atggtaaact aggaacaaga agcagaaagg aacgataatc attatgatca
    41881 aattaattgc atcagatatg gacggcacat tattagatgc ccatatgagt gtttctcctg
    41941 aaaatgccga ggcgatacgt tttgcaaatg atgccggtgt tgagttcatg gtcgctactg
    42001 gtcgaaacta tcaagaagct cgcgcagctt tagatgaggt aggaatcgat tgtgcgatga
    42061 tcactttgaa cggggcacag gtatttgata aagaaggaaa ttcattgttt accgtgtcga
    42121 ttccaaataa tcaagcaatc tctgttttag atattctaga tgctaacggt atttactatg
    42181 aagtagcaac caacgatggt ctttattctg aaaatcaagc gaaacgaatt gaaagttttg
    42241 cttccatggt ggctacccat ttacctcacc ttacgtataa aatggcgatt gccatggcct
    42301 cagctaagct ggagttattg cacatcacat acgtggacag tattcgtgct attttggaag
    42361 aaaagaatct ggaagtttta aaaattattt gttttcatac agaagggcca gctgtattag
    42421 gtccagttgg aaagcagatt tctcttttag gcgatctagc cgttacttcc tctggtcaaa
    42481 acaatatcga agtgaaccat aaaaacgctc aaaaaggaat tgctgttgcc catgtcgctc
    42541 acgagcgtgg gatttcttta gaagaagtca tgacgattgg cgataacttc aatgatgtca
    42601 gcatgctgca agtagcagga gtcagtttcg caatgggaaa tgcagaaatc gaagtaaaag
    42661 attatgccaa atatacaacg gacacaaacc ttgaatctgg cgtaggaaaa gccatattgc
    42721 gcgcgattgc agaagacttg tagttttatc tagaaaagag ggatatagat gtcagaattt
    42781 ttcattcagg aaaagcagct tggacgtgca actcggacaa ttgtcaaaaa cgaaaaagga
    42841 cattccctgt ttttgatggt tggtcgctgg ggaacaaagg gcgatgcatt gtctctttat
    42901 gccatgaatg gcgatctcgt tgctcacatc aagcagataa gcctgacatt cggtacgcgt
    42961 tttgagctgt ataaagagtt cgaaaaggtg ggaaccatgc agaaaatatt caattggccc
    43021 ggtgactttt attatattcg tagacttcac tggacagtcc aaggtgatat ctataatcat
    43081 caatatcaaa tccatcattt caatcagcaa atcatgaaaa tggataaagc aacacttttt
    43141 tcaggagatt actatgtatt ggatgtctca aatgatgaag atgctccagt ttgtatttgt
    43201 attgctgcgg ttttagatta ctggctctac cgtaaagaca aaagtcgcga taagcctgtt
    43261 tcttaccgac ttaacttaag ttaaaaagat gtacctgaaa tgcggaaata cgcatttcag
    43321 gtacatcttt ttagatattc ttttgcatat gatcataaag atgaccactg atcatccgct
    43381 gaccgacaac tttgaagtca tggcgttcgt ataatttttt agcctttgga tttttttcat
    43441 ccacacttag accgatgacg gagcgattag ctttcttcgc caatttaggt aatgcttcta
    43501 ataatcgcga accgatgcct tgtcctctaa aatcttctga tacactgata gagtccaaat
    43561 accattcgtt gggaaacgtt tctttatcaa tgaacaaacg tgtagacgca tctagctgat
    43621 atttctctaa gataggtacc agtggctgat cgatgattga ttcttcttca tctgtataac
    43681 cgtaagcaac tcctgcaact ttaccgtcta tttcttctac gatacctcgt gaataactgt
    43741 aacgataatt tggatcagtg attgcttctt ctaaaatctc taaagtcttt tgttcccctg
    43801 tctgcttcaa aaatggcagt tccatatctt ttagaatcac taagatcaat ggggcgattt
    43861 ctggagcatc ttcttttctc gcaaaacgaa tcatagtttc ctctcctttt ctccattcta
    43921 acatgcagaa aaagaaatcg caaaatcgtt attttaaaaa atcttcaatc ttttcagtaa
    43981 tgaaataacc atgagtaacg attcttgccg cttcagttcg gcaataaggg cagacgactg
    44041 gcatttcttt atcattatgt tcgactacat tattgacttc ttcgtatgca aatttttttc
    44101 cgcaattagg gcatttcatt ttttccatgt tatctcaact tcctttcatc tttactctct
    44161 tagcttactc ttatattgta aaaaagagaa gcaatatcct tcttctatgc agatatccat
    44221 acctgacggt cctgttctcc atctattaat cggactttat aataaggacg ttcatctttg
    44281 actagaagtg tccactcttt cacttttgct tttttcccgt agtagctgac tgcttccttc
    44341 atcgctgctt gcggttgttt gaactcttcc gttttttcta tatcaaaaag atgttctgcg
    44401 gccttttccg tgtcatttcg tacggttgtt ttcccagtgg atggattgac tgctatgact
    44461 tgtccttcac aaaaaaactg gtattcatat gttgcattcg taggattctc caaatctttt
    44521 tcaactgcaa aatgaatagc agatatgtta tgttcttttg tttcgttttt tacgattgct
    44581 gctgcttttt tcaatgagat ccgatattcc tggtcactaa tatcatccat gtgaaaagcg
    44641 gcattgagca gtcccgtcat accggtaatc cctattacga tgagggcagc aacaccaaac
    44701 atcatttttt tcattcttca ttctcctgtt tctttttttt aaagaatatc aagaaatgaa
    44761 cgaatgaaaa atcgaatgaa acgaaaaaaa agtgacaatt ttgttatctt tattcgtgca
    44821 gttctaatgg caatccgtct ggatcaaaga aaaacgtcat tttttttcct gtaaaggtat
    44881 cttctctaat cggttctgat tcgatcccta aggactgcaa ttctgcaatt gtttcttcaa
    44941 tatcgtctac tttgaaagca agatgacgca agccacaagc ttctggatag tttggtcgtt
    45001 gtggcgcatt agcaattcca aaaatctcca attcagcact tcctagtttc agatctaatt
    45061 tatagtcatc tcgttctttg cggtaatttt ctctgattac ttcaaatcct aatttattaa
    45121 cataaaaatc acgtgatttc tgataatctg aaacaatgat ggctatatga tggatcgttg
    45181 taaggttcat atgagcactc ctattcttcg tttaagctcg gatctatatt aatctccagt
    45241 tccattgtaa atgtgtcaga ttgaaaaaaa tagctgtttt tcctttttat aagaaaaaag
    45301 gcaaaaaaaa cagaaagtag gtcctccaag acactcttcc tgttcccaat ataataaatg
    45361 aaagtaagaa attatatttt caagaaaaca aacagaaaat tatcataaca caaattattt
    45421 ataattgaaa gactagtttt ttttcaagaa aagcatacaa tagattgtgt tagtaaatac
    45481 agaacacact acatttagtg tcttaaggag tcctcataca tgaagtcata ttttcagttt
    45541 ttagctcatc agctaaaagg ctggccgcaa caaaattatt atcttttctt tttcagtctt
    45601 ggctgccagg tcatgactct tgtcaatagt cccatcactt ggctgtccgt tattacattt
    45661 atcggtacca cgcttggtgt attgtgtatt ttatccatca atgcggcaaa atcagtcaac
    45721 ggtattttag gtattttgtc tgcgatttgt tttattatcg ttgggttttc agcaaagaac
    45781 tatttaagta tcggtgaaca gattgcttat atgatcacat tggatatccc cgtattgtta
    45841 agtaaagaat ggaatcataa tatggcttca aaaatccgaa aattcactgg aaaaagctgg
    45901 tttatcgcaa tcatcagtac tttccttgtc tatcttgttt caggattcct gattggtcgt
    45961 tatacagatg atcctcggcc gtgggtagat gccattgctt tttctattag cttgactgct
    46021 ggtatcatca gtttcttgcg ttacaacaac caatattact ggtggttagc ttcagggctt
    46081 gctcaaatgg tcctttggta tatttcattt acgcatggat ctgcaagttt ggcgatgttc
    46141 gtgaacagct ctgtttactt gctgaatgat gtccttgcat ttaccgtttc accttggtat
    46201 aaccaaaaag aacgtgaacg tatgcaaaaa atggaagaag aatactacaa cgcacaacaa
    46261 cacgcataaa aaaactgagc gtgggacaaa agtaaagaac acttttgtct cacgctctaa
    46321 acacgtataa acggcggaat cagaagcaac tccttcggaa ataagctgaa attcacaaaa
    46381 atttgaaaag caattttcgt gaatttcttc ttatttcttg gagttaaacg cttctgtccc
    46441 agcctctatt ttttatagta attccttcag atactttctt gcctcatcat tgaaacgcag
    46501 tgattcttct aacttctgat aatattccaa cgcttgtttc tgagcttcag taaaacgata
    46561 atgttttcct ttccatttgt cgattgtctc ttgcacattt ccagattgga tatctttcac
    46621 tactagttgc catttttctt ttgagactgt acggtctttc ttatcagcag attgtatagc
    46681 ttctcgttct ttacgcaata cttttaaaaa accatttctg actatccgag gaatgctgtc
    46741 gaagaaccct tctgtaaaac catagcgaca atattgcttc caaataaata gatagatttt
    46801 tggttggatg aatcgttggt ttttcgcaaa atattccatc tgagcagtga cttctggtgt
    46861 tcgttgacgt tttgtctttc tcaacacgga aataaatgtt tcaaaataag cattaggatg
    46921 tactggcact tcttcatata cgatggattg ccaatcttta cgtaaaaatg cgcgatagtt
    46981 gatcaagaat tcttctacat cctttactaa ttcttctgca aagtcgtcaa atagttcttt
    47041 ttttatctgt cgcttttttg actgcccatt gatgtgttca cttattttct tgatttcatt
    47101 ttccaatgct tgataatccg ctatgtaaat cggcatttct acttggcgaa attctgcgag
    47161 ccgctgagct aattttatat ccggtaaata tggctgtttc atccgacgat tttggtacaa
    47221 gacaaaacag tatttttgcc atagtccttc aggaaaatcg atattcttct gcttaagcca
    47281 taataattcg tctaaggcca gatcaacttt tgtcattccc tgatggatcg aagctgccac
    47341 tgtcggagag acatgcaggt gatcggcaaa gtggttgatg cctagtttta ggatctttcc
    47401 ggtttttggc gatttaacga tgtattgcac ttttaattct ctaccacact cacaatacaa
    47461 tttttgctgg cttcgttttg ttcgaaaaaa cggattgatc ttgaagtcag aaaacaccca
    47521 atctgttgca gctaaataat gttcttccat aaaacgagag ctgattagat atcggcggtg
    47581 cttatcgact agttcccgct gttttttcgt taattttgca tagatctccc aacgttgact
    47641 gcttgtgtat tgtttagaaa ttttgatggg atagcttttg ctgatttctt ttggaaacca
    47701 ttcttcaaag acggattgcc attcttccac ggctgtttct ttcctttcta attacaaaaa
    47761 gctggctact aacataacgt tagcaaccag ccagtgtttc ttgctaaatt agtgagttgt
    47821 tccggcattt ccggaaatat cttctttatt ttctactgct gcttcaactg cataagtcaa
    47881 agaagaagca atgtcttcta aagacataga aggcgtaccc actggacgat cgatcacttg
    47941 atcgggtgag aatggcacgt ggatgaaccc acctcgaatt gccgggaatt gtgtttcgat
    48001 caaatgaagc aaacgataca tgatatcatt gcagacaaat gttcctgctg tataagagat
    48061 gtacgctggt agaccatgat cttgtacatt ttttgtcatt gctttgattg gcaatgaggt
    48121 aaagtaagcg gctggaccgt tttcttctaa agccgtatcg aatggctgat ttccttcatt
    48181 atcagggatt cttgcttctg ctagattgat tgcgacacgt tcgaacgaga ctgctgaccg
    48241 cccacctgct tgtccgacac agatcacgac atctggttgg tgctgttgga tggcttcttt
    48301 gactacttga ctgctttttt cgaatacggt cggtacttcc actttgatga tttcagcacc
    48361 gctgatttca tctggcattt tttttactgc ttcataggct ggattcactt tgtccccacc
    48421 aaatggatca aaacctgtta ctagtacttt catctgttgt tcctccgtcc gattgattta
    48481 acatatggtt atcttttatc ataccatttt ccttgaacag cgtaaataaa ggaaacaata
    48541 gtttaaataa cataacagat caaacttaat atattcttat aaaaaaatag tgttccacta
    48601 caatgttaga agaggttgcg acaattattc tgtcacaacc cctctcttct attatttaaa
    48661 tagaatcata taagcaattt ggaaaactag cataaataac gcaataaaca actggttttt
    48721 gatcactccg tatttgtctt tcatctccag catcgctaca ggcacgatat tgaagttagc
    48781 agccatcggt gtcagcaggg tcccacaaaa accgcaagtc aatgcaacca ttcctattaa
    48841 cgctggattc gctccatgac taaatacgaa tggtgcaccg atcccaaccg tcatcacggt
    48901 gatggccgca aatgcattcc ccatgattac cgtaaatatc accatgccaa gagcgtaaat
    48961 gatgatgccg atgttcacat ttccttctgg aacgatcgta cctactgcat tggaaatcac
    49021 tgtcccaact ccagcgcttg taaataccgc acctagagaa gctaaaagca ttggcaacat
    49081 gcttaacggc cctactgtgc ccagcatatc tgctgcatca tctaaaaatg tacttggtcg
    49141 attatctcga gaaaagaaca tcaagattag catggctgca aaaacaccga cgcccacgcc
    49201 gactaaagca cctaaattgg taaatagagc aaacaagatc gcaaagacac cgatactcaa
    49261 agctggaata aaaattttca ttcctagttt gtctgacatt ttttccatat attcttttga
    49321 tggaagccgg ctttctcctt tgctgacttt cttagcaatt gctggtatgg tcatcgcaaa
    49381 gatcaagcca ccgttcacga ttgccggaag ccatcttcct cctgcaataa ctacccctaa
    49441 gaccgtccag aaaaaggctg acccataacg atgaggattg gttttatctg ttaaatttct
    49501 tactccagtg taaatcaata cgagtcccat cacgatataa aggatctcca gtaatttatc
    49561 gcctaataaa atatcaggat ttgtaaaaaa gtccatctta ttgccccttt cctggataat
    49621 atttcttcgc taatttcttt tctttaagat agaagtagac acttgccaca actaaagccg
    49681 tgatagccac tggaacttcc actaaagcaa gctgtcccaa tgttacgtca tatcctagat
    49741 ctttcagtgt tgattggact agcaacgccc ctgctcctcc gatgaatagt acttggccaa
    49801 agaaccagca gacattttcc atagctgaag ccataccttt tagttcttct tcatgcttag
    49861 gatggacttc taaccctttt gattcgatgg tccccaatgc catcggtaaa atgattggac
    49921 gaacaaatcc agcaactcca ccaaaactca cgttaaaagc cgcaaagatc attcgaaaga
    49981 tcccataaat atctacaatc ataccagcag atactttctt gaatcgcttg atcaaggaag
    50041 ccgctgattc tttcagacca tttctttcaa gcgttcctgt tgccaacata atgatgataa
    50101 aaatcgccat cccgcgattg tttacaaaac ttgtacctaa aagttctaac attccttgaa
    50161 tgccaagacc gccagtcaaa gctgtaacaa ctaaagcaac cattacgatc aatatcgagt
    50221 ctaatttaaa tgcaaacccg agaataacaa tcaagacgcc taaaaggcta agataatttt
    50281 ccatatattt tcctccataa aatgacaata tttttttaat tataaagcaa aacacataaa
    50341 aaatatagtt gttttctcac gaaatagaca ctatttttaa atatttttcg ttattttttt
    50401 atcacaaaaa ttatcttact tattgtaagg taaagctttt tttaatttat tgcccgataa
    50461 tatatagaaa taaggtctag ttactgtttt ttttaaatga ttaataaata acaacttctt
    50521 tctatgaaat tgcaaagcat tcatcttctt ttccgctaac gatatatccg tcagtgcttg
    50581 gtacacttta ctaaaaagta tgagattgcc gatatctgga taggtgtgct atactacaga
    50641 aaaagatata caatctgcca ccgggtagga taaagaggat gatcattcca ttaggtcttt
    50701 gaagggatga ttttcctctt tttgtgtatt tttttatagt taaggaggaa tgtaagtatg
    50761 gcatggatgg aattaatcat agcaggaatt ttggaagtat tctggtcaac gatgatgaaa
    50821 tggagtgatg gtttttctaa aatcaattat tctttttaca cagtgattgg catgattgct
    50881 agtttttact ttttgtcaaa ggcaatcaaa agtttgccga tgagtctctc ttatcctatc
    50941 tggacaggga ttggcgcagt tggttcggtc ataattggtg tggtcttgtt tcatgataag
    51001 ctgaatcttt ccacttggtt ctttgtgggg atgctactca tcagtatcat tggcatcaag
    51061 attactagcg gccactagac acttggaata agtactgatc agaaaaaata agccttttta
    51121 tttaatattc aattttttta tgaaaaaata agaaataagt ccaatgacct agcgacttct
    51181 ccactcatca ggtgtatgct tgtactatct atagaaaagg agtgaatatt tttgaaaagt
    51241 ctttcggtcc aagaattatc caagaacttt ggtcacaaac aagccctcag cgatgtcagt
    51301 tttagcttat cccctggcaa aatcgttgga ttagtaggtc ctaatggcgc tggaaaaaca
    51361 acgatcatga aagctatttt aggactgatc cattactcag atggaacaat ctgtattggt
    51421 gaaaatgaga tttctccctc tagtcataaa gggttggaac aagtaggagc attgatcgaa
    51481 tacccgggta tctatccatt cttaacaggc tatgatcatc tgaagttatt ctctgaaacc
    51541 aacgatgtat ctgctatcga cactatcgtg aatcagctca agatggaaaa gtacattcac
    51601 aaaaaagcga aatcctactc gttgggaatg aaacaaaaat tgggaattgc tcttgcctta
    51661 ctgaaccatc cgtctatcgt tattttagat gagccgatga acggtttgga tccacaagca
    51721 acaagagatg tgcgaaaaat cattaccgac ttggctactc agggcacctc tttcttgatc
    51781 tccagtcact tactcagcga gcttgaaaaa atggtcgatg agctgatcct gatcaatcaa
    51841 ggaaagatca tcaaacaatg tacaatggct gaattgaacc aaacagcgca agatttcatc
    51901 gttatctcta caacaaatga tctagctgct cgaacgatct tgacagaagc tggatatact
    51961 ttggaagatc ctgataaaat caagctttta aaagaaaacg aagaattatt aggaaccgtg
    52021 atccagctat tgtctgcaca aaatatccat gtgacagacg tccagcatct gacgaatgat
    52081 ttggaatctt ctctattgga aattctggat tcagtaaagg gggaagaaga aaaatgacat
    52141 tgcttgtaaa acaagaatta tttaaattga tcaagaaaaa gtcaactgct gttttatctg
    52201 ttctattagt tgttttgctc ataggaacag cacttctagc caaaaaatac acgacgatca
    52261 ttgatccagt tgaaatgact gctcagcttt ttagtgccac atcttggatt gtctttatca
    52321 tgattgcagc tgcaagcacg atcatttcga tggaagcaca atatggtaca ttgaaaaatc
    52381 tcctttatcg aaagtattct cgaggagaaa tattagtaag caaatggatc acattagtta
    52441 tttattctgt ttatttatac cttttagcta ttattgtcac tgtgttgatg aaactgattc
    52501 ttttcccttc gatttccttc acggagaagg tttctactgg tcaaacactg atccaaagct
    52561 tgttcactta tactttgggt agttatatcg gtttatggct gattttaagt ttagtgttga
    52621 tgattgcttg ctttatcaat agttccggcg catccatctc agcaggaatc gtcttttatt
    52681 ttgcttcgtc aatcatatct ggtatcctta ttgcactcat ccaaaaatgg gagtggatca
    52741 aatggaatcc gatcagtatg ttgaatctgc aaaaccaaat tggaaacgaa gagatcatga
    52801 agcaattgac tcatctttct actaatcaaa tgctattcgg taatttagct tacatcgttt
    52861 tgttcttagc attaggatat ctcgtattta agcgaaaaaa tgtatgatga ctcatcaaaa
    52921 aagaggctgt gaaagagacg ttcagcctta ttgccgattg gctgtctctt aaacaccgtt
    52981 tattctgaaa aaggagctgt gacaacattt gtgtcacagc tcctttccta gtatgttttt
    53041 gaataaacga caggctcaca acctctcttt atacttcttt tatacttcta tacgtgaagc
    53101 atcccagtgg caaataaaac cattgcaatc actccgacca tcgtcacacc tataagtaaa
    53161 atcttatcta agtggatatg ttgtacaggc tcgttttgct ccttacgtgc tttgaggtaa
    53221 aaataaatgc ctggcaagaa aagaacaaga acaagcatta cttcattaaa ggctacgact
    53281 agcatagccc atacttgaaa ggcacttgct aaaagcccta ctaaaaattg gacccattct
    53341 ttccgctgat aagaaagttt catttggtac aatcctaaga aaagccacgt gaagaaaata
    53401 gctgctgtac caagtgtgta agcaaagtta taagcactgt cagtgaataa taatgaaagt
    53461 aaaaagacat tcgtacataa cgtcgtcaat acgatagcat aagttggtgc cccatttttg
    53521 ttgagttttc cccatgcttt aggcaaaagt ccgtcttcag ccatgtttcc cattgtttca
    53581 atcggtaaga tcgtccatga gagccaaaca ccaactaaag aaatgatcaa accgccgttg
    53641 atcacgactg ctccccattt accaaccatc atttcaaaca catagcccat agcaggctgc
    53701 gccttgatcg tttgcagctg attcatcgtc attgtcccat atggaagcat ggaaaccaag
    53761 acgtaaataa taatcaagcc gaatatccct agaatcgttg ctttcccaac atctgattgt
    53821 ttttttgctc gtgaacctac gacagaggct ccttcaatac caacaaatac ccaaagcatc
    53881 accatgatgc aactcaatac ttgactggaa aacgggatcg gctgtccatt cgcattcaat
    53941 ataatgtcgc tagaaaagtt atcaatgaat tgttggatcg aaaacgtgct gatagctact
    54001 acaataaata aaaataatgg cactaattta cagaatgtga cgatagcatt gacgaaacta
    54061 gcattttcga ctccccgatt cactagccat gcatatcccc ataaaaagac tgtactcatc
    54121 acgatcgatg ccagattttg cccaccttca aatactggga agaaatatcc taatgcgctc
    54181 atcaacaatg ttgcaaaagc tacgttgcct aaccagcatg tgagccagta accccaaccg
    54241 ctgataaaac cagcgaaacg gccaaaacct tcttctgcgt aactaaagat cccgcctttt
    54301 aaatctggac gttttttatt gatattattg atcgacaagg agagcatcaa cattgctgtt
    54361 cctacgagta cccaactgaa aatagctggg ccgccagccg atccggagat gtccgtcata
    54421 ataccaaata cgccacctcc aatcgctgaa ccaattacta aggcagcaag tggaattaaa
    54481 ccaattcctt ttttctgttg ctctgtatcc atgtaagcat cctccaaaat aaaaccgctt
    54541 ttatcaaaaa gtataacaaa ccttttttat ttttacttaa ttaataaaaa ctttaataga
    54601 aatataattc taccggcttt tttctcatta tacaagcaaa gcgcctagtc cctttccaaa
    54661 ttacaccacc aaaaaactta aaaaagatgc tatactaaaa ggaaagaatt ggaggatgat
    54721 ccatgaacat tttatatata tcgatttcag gaaatacgcg tgcctttgcc aaacatctag
    54781 cagaatatgc tgaaaaaatg catgcagaag atcctgtcaa tcctgaagtt actttaaaag
    54841 aaatccatga aaatagtgat tttacgaaag aaacagaacc attttttact ttcgttccta
    54901 cttatttaga cggcggaaat ggtttagata acggtgatac agaaatcttg accgaaacga
    54961 tgcgtgaata tctggaacat gaagacaatc ataaactttg tcttggtgta gtcggtagcg
    55021 gaaataaaaa cttcaataat cagtattgtc taacagccaa acaatatgca caaacatttg
    55081 gctttccttt cttggcagat tatgaattac ggggaacacc atctgatgtg acacgaattt
    55141 atcagatttt agcagaaaac aataaataat aaaaaagaag aagctgaaaa atagatttca
    55201 gtttcttctt tcgtttctat tgtttctatc atattaagct ttgacatcca tcacaggtgc
    55261 ttttgctttt gctttacctg ttttttccaa gacaaagttt tttacacgat ccatattggt
    55321 taccaagacg atcatggatg tttctttgcc tgctgctttg atcgcttcta agtcagcttc
    55381 tgctacaagc gtatcaggtg tcacttgctg cccttctgtt actttcacat caaatggcgt
    55441 accgcctaag tcaactgtgt tgattcccat atgaagcaag atttctaaac catttggcgt
    55501 tgtgatccca atagcgtgtt tcgttgggaa gacagagctg actaccccag taactggaga
    55561 atagatatgt ccgttttctg gttctacaaa gtagccttca cccatcatct tttgtgcaaa
    55621 aactggatca cttgctttat ctaaagaaac aactgttccg tcagcaactg atgagaggat
    55681 agtcacactt tcagctgaag tttgaggtac tactttttca ggcacttcat ttactgtggc
    55741 tgtttcagtc gctaattctt ctttttctaa acggtcttta ggaataccga agaagaatgt
    55801 agcaacgaag ccaccagcat aagctgccaa taatccaagg atgtagccta accatttacc
    55861 gtcagagatc aatgggatca aagcggctcc tgaaggtcca atagcgatag ccccgacatt
    55921 tccgatcatt ccgatcactg ccccgccgat acctccaccg atacaagcag taataaatgg
    55981 gcgtcctaga ggtaatgtta ctccgtaaat caatggttcg ccgattccta ggatcccgac
    56041 tggtaaagct cctttgatca tttctgttaa ttctttatct tttttgcagc gaatccataa
    56101 tgccaatgct gcacccactt gtcctgcacc agccatcgca agaattggaa gcaatagcgt
    56161 acgaccagtt tcatcaatca tttgcacatg gattggagtc aaaatttgat gcagtccgaa
    56221 cataaccatc ggcaagaata atgtgcctag aacgaagccg gcaaatgctc caccaacgcc
    56281 aagtacccag ttgatcccac cgaccatgcc atcagaaatg aaacctgcta aaggcatgat
    56341 gaagaaaatt tcaatcagac cgatggcaat caatgaaaga gttggtgtaa cgatgatatc
    56401 taccgcatca ggtactactt tatgcagttt tttctcaacg attgacaata gccaaacagc
    56461 gaagatgaca cctaggatcc caccttgtcc agctgcaaga gcttcaccag taaataagtt
    56521 tttcagtggt gcttccggat tcatccctgt cagcatcaca acggccccga taactccacc
    56581 aagagttggt gttgcaccaa aaacttgtgc agcattgata cctgtataga taactaggta
    56641 gctaaacatc ccgtttttca agatgttcat cacatcgata tattgttgcc atgttgctgc
    56701 atcaagtgtt ccggctgtga ctaagtttgc taaaactgcg gcaatccctg ccacgatccc
    56761 agtaccgaca aatgcaggaa tcattggcac aaagatatta gaaatgtctt ttaataccga
    56821 tttgatttta gatggttttt gtttcgattt ttgtgccgct ttcatttctt gtgcccgttc
    56881 gtttacacgg tcttttccag atgctgatga atttgctgta gctgtactta cagaagaaag
    56941 tttttctcct aatttcacgc ctgccaaatc aaccatttgc tgtgctactt tgttcacttt
    57001 cccaggtccg atgatgactt gaagctgttc atcttctact acaccaagca ctcctggaat
    57061 cgcttttaat tcagagacat ttacaagatc atcattgatg atcttcatac gcacacgagt
    57121 catgcagtgg acaatgcttt ctacattgcc catgccgcct gcccctttat aaatttgttt
    57181 tgccagttct tccaaagtca gttcgttttt tgccatggtc ttttccccct cataaggtcc
    57241 cttttacaaa tccgtttgct tcagctaatt ttgcttgagc ttcctcttta tcactatttg
    57301 tcaaaatcat gacgatagcc agcttaacat tttgatctgc ttcttcaaag tacttttcag
    57361 ctgtttcgta atcagcttct gtcgcttgca tgatgattcg ttttgagcgt tcgattagtt
    57421 tttcatttgt tggtttgaca tcgaccatca agttattgaa tactttacct ataccaatca
    57481 tactgatagt agaaatcata ttcaagataa gtttttgtgc tgttcctgac ttcaatcgag
    57541 tagagcctgt caaaaattct ggacctgcat cgacttcgat tgggaaatcc gcgtgtttac
    57601 tgatttcggc ttgtttattg caagaaatcg ttcctgtgac agcaccgatc gattttgcgt
    57661 aatctaatcc accgatcaca tatggtgtac gaccgctagc tgcgatacca ataactatat
    57721 cattttttgt caaattcagc ttgattagat cttcttgccc tagctcataa gaatcttcgg
    57781 ccccttcgac agctacagtc attgcttctt ctccaccagc aattagacct atgaccattt
    57841 ccggttctac accgaatgtc ggtacgcatt cagcagcatc taacacacct agtcttccac
    57901 ttgttccggc tcccatataa atcagacgtc cacctttttt aaaggactca atcgtgttag
    57961 caatcactgg ttcgatactt gtcagttctt tttcaaccgc agcggccact ttctgatctt
    58021 ctttgttcat tagttgaacg gcttgagaaa tactcatctc atctaatcca aaagtttctt
    58081 ggtttctgcg ttccgttgtt aggttctcta aattgatttt gctcattttt atcttccttc
    58141 ttttcttata aattgatagt tcataccagc tttgatttgg ttgatcaatg gtagctcttc
    58201 tttgataact ttagctacta cattcacttt ttcatccgct ggcaaatcat atttggttaa
    58261 ttggatctca cccatatagc gcaaatactt ttcgttatct aaagtaatag accctttcat
    58321 acgcgtagct gtatttcttg ctgggatagg cggaatctct cgaaaacgtg catctacgct
    58381 tcgtatgaca tctcttgcat cgtcttgccg attcgtatgc ttccctaata tatattcgta
    58441 aaattcttca tctacaggtt ccgtatggag caagactgtc tgttcttttt ggaaagaagc
    58501 aaattgctcc tgaacgtttt ctgacagacc tgcatctccg atgtaaacaa tatccgtgtt
    58561 acttgctaat agatctagag cgcctgcaag aggatggatc cctcgatgtt cttccaaagt
    58621 tggcaatcct tgatatagtg ggcctctcaa ctctgtatct cctggtacaa aaccttggac
    58681 aaggagacct tgaattttga gccattgatt ttttttctga taccattctt tgtccagccc
    58741 tgtttcggga cgtggataat aattatgcca agcttcaatc tgtgagaaat cagcttctgc
    58801 ttctttcaat tcatcgatat ctttaggcgt gatcgtgcta gcattcaaac tgattttcaa
    58861 ttgatgtgac cagtcggcaa tctgctgatt ggaaatatga taatccattc ttaaacctgt
    58921 tacaccaatt gctttcaaag gcgttagatc ttctaatgaa aaacccgctc gttccaatgc
    58981 ctctcctgaa atatcgacca tcaattctag tttattcttt ttcgcttcgc ttcctagttc
    59041 gatcaatcgc ttttgatatg ccgaaacatc atcttctggt atatgcatgg aagtgaaaat
    59101 accgacaaag ccattggatg ccatttggcg gatatactgt ttcttctctt ctgacaaaga
    59161 atcgttcata aatattgaaa agccaaacat attatccctc tttttctgta tccgtcttca
    59221 tttctatgac tagagtatat atctaaagaa acaaaatttc aatactttta ttaaaataat
    59281 taaatttcat ttctaaaggt tgagtttata ttatcaaaag aattgtcata acctaaaaaa
    59341 ggcactgcta agcaaaagca gtgccttgaa atattttatt taaataacac aaaaacataa
    59401 ttactcataa gaaaccaatt ctgtattatc taccatgaat gtaaagaacc cctcattagg
    59461 catcggatga aaataagcat tgatcactct tatcaaggca ttatggcaaa ctaacagata
    59521 gacattttct tcgtcttcga tgcattcttt caataaagga acgatccgtg catacacatc
    59581 taagactgac tccccatttg ggaatcgtac agcgaacgct aaacgtgctt tttgaaagtt
    59641 ctcatctttg cttggcagtc catcataatc cccaaaatcc atttctacca atcgttcatc
    59701 aacggtcagc ggcaagctga gacgatcagc aactgcttgt gctgtatctc ttgctcgttg
    59761 aagaggggaa tggatgattt tcgtgattgg aacaggcaaa tctactacct tttctgctag
    59821 tttctgtgcc tgcatctgtc ctttttcagt cagcggcaca tctgcccgtc cgcaaactaa
    59881 tccttgtgcg ttccaagttg tttctccgtg tctcgttaca taaagcatgt gattctctcc
    59941 ttcgttggca aagttcccct taaccatacc ttgttgttct tgagattaca agggttagat
    60001 tctctcaaga gaaataatct cagtagatac tttatccagg aaggtttgat catgttccac
    60061 tagtaacatg gcaggtttca cgttcaagat cagttgttct aattgttctt gattgaagac
    60121 atccaaataa ttcaatggtt catcccatgt atatagttca gctggctgtg ataaagattt
    60181 agccaattcc acttttttcc gttggcccat actcatctgc tcgatcttgt tatgaaaaac
    60241 atctctttcc atcccaagct ttcggaggtt gttcaaaaat gcttggtagt ctacttggtt
    60301 tttctctgca aattccgcca acgttcctcg attgtcttca taattttggc ttgcataact
    60361 aatgctcaga tgttttggct ggtatttttc tcctataacc ttgccgttga atgcccccag
    60421 aagataatgg ataatggatg actttcctgc accgttagga cctgaaatcg ccacccgctg
    60481 atgaggctcg attgtaaaat gaattggctc gaataacaga ttttcatacc ctaattgaag
    60541 atcttctacg cttaaaagtc gcttatggtg agacgcttgg ctattcatcg tcaaagaatc
    60601 gatatattcg atatctttta atagtttttc tttctcgctg atctgggtct ccatccgatt
    60661 cacgattgct ttggatcgtt tcatcgtccg tgcagcatca gcacccactg ctcctttatt
    60721 cactcgtcta gattcagtat cgatgaatcc gacttgtttc tttgttttat ctccttctcg
    60781 ggaacgagac cattcggctt tttcagctgc tgttttcttt agcctactga cttctttttt
    60841 caatttttca ttttgagcca tttcaaattc atcacgaagt tttttctgtt cttcatagat
    60901 agagaaattc ccttgataaa gttccagttg acttttttcg attgctaaaa catggtccac
    60961 tacttcatcg ataaatcccc ggtcatggct gaccacgatg aagccttgtt ttttcttttt
    61021 caaataagcc gctacttgtt ttctaccaga gatatccaaa tgattcgttg gttcatcgat
    61081 taacgggaaa tgagtgtcat ccacaaataa aagtgccagt aggacttttg tcttctctcc
    61141 ccccgatagt gtgctgaatt ctctccataa gatttcagga tctgtttgca tcaattggag
    61201 ctctctttcg atttcccata tctcaaaatc cgtaatatca tttaacacgt aataggttaa
    61261 acgttcttta tcttttgtct gttgcgggaa ataggcaaat tcttgctgat ggattacttg
    61321 cccttgataa ggtagtttgt tttgtagaat attcagtaaa gttgtctttc ctcgaccgtt
    61381 tcgtccgata agtcctagtt tccattgtgt gtcaaaattt agatttgctt gttcaaataa
    61441 taatgtgcct tggctgtcgt agccgaatgt cagatttttt atttcgattt tagacatttt
    61501 ccatcacctc gtaaaaaaag accagtccta ttttcagaac tggctaaaga ggatgcaagg
    61561 gttggataca cacaaaaaga cccatacatc gaaaaaacca agccaatccc gaaaatctgc
    61621 acactgcttc cttgtctcca caaggtacag tctgaatgca gctttcatca atcgacttaa
    61681 tttttcaatg cacggatccc tcactttgtc ctatatttga aattacgata gcataaagaa
    61741 aatgattttg tcaactactt cgggaggatg gtgaaaaatc tgctaagtgt ctgtcctaag
    61801 atttttgttt tttctaatgt ttgcctgtgt tccattgctt cttctaaacc tattggaccc
    61861 aaatgaatac ttaagacaat tgggagaaaa tcagaaagtc cttctagctc ttggtctcta
    61921 cttccgcaaa tagcgattat tggttttcga tatttttttg caagcactgc tacaccgtat
    61981 ggaacttttc cgtggatcgt ttgctgatcg atccgccctt ctcctgtaat gatgacatct
    62041 gcttgttcga tctttttttc caatccagtg atttggctga ctaaatcgaa accagaaacc
    62101 atcttcgctc ccaacaaaaa aagggctcca ccaataccgc ctgctgctcc acttcctgga
    62161 atatcatcta aatccacctc ccagaaatct tttatttgct gagcaatctt tcctgcttgt
    62221 ttatctaaga aagctagcgt cgtatctatt cctccttttt gtcttccaaa ttgccaagca
    62281 gctccttgtt gacctgtata tggattggta acatctgcag cgataatcaa ttttacttta
    62341 gaaacaagaa cgtttcttcg atcaaaatga agttttttag tagataataa aggatttcct
    62401 tctgtgtacc cttctaaaga agcacccaag gattggagta atcctagacc accatcgcta
    62461 cacccgcttc ctcctaaagt gacaataatt tgttctactt cttgaagcag tgcatcttta
    62521 ataagttctc ctaaggcata actggaagca agtcggatag tttgatccgt tggtttatca
    62581 agtagatcta accccaatgc ttgtgcagat tcgatgactg cggtgttttt tccttgccaa
    62641 gttgtcaata aatagctgat ttttcgctga cggaataaga gatccatccc atcaatggta
    62701 cgccatgttc ccctgagcgc gtaatagatt gcttctgcag tattttctcc gccatctgca
    62761 atcggcacat tgatttttct tcctttacga tcttcccagc catttagaac tgcctgattt
    62821 agttcaaatg aagaagcact tcctttaaat gaatcaattg ccgccaaaat atccatctgt
    62881 atccctcact ttcttcttaa gtaagacact ttttttcatt tttttcaaac aaaacaatgc
    62941 tattttcttc catttttcta tatactaaaa gggaactcat tgaataaagg agagaaaaaa
    63001 catgaaaatc gcaatagctg gggccggagc aatgggcagc cgaatcggat tgatgctaca
    63061 tcaaagcgga aatgaggtcc tcttgatcga tcgttggcct gctcacattg aagccattcg
    63121 tacaaatggg ttgattgctg actttaacgg taaagaagtg gtcgcaaaac tgccaatcta
    63181 ttcaccagaa gaaatcatcg aaagcaacga acacgtggac ttgatcgtag cattaacaaa
    63241 agccaatcaa ttagatgata tgttttgttc gatccaatcc attattactg acaatactta
    63301 tgttttgtgt ttactaaatg gattaggtca tgaagatgta ctggaaaaat atgtgccaaa
    63361 gaaaaatatc ttatttggga tcacgatgtg gacagctggt ctagctggtc ccggaaaagt
    63421 cacattgtta ggtgatggag aaatcgaact agagaacttg gaaccagaag gcgaagcatt
    63481 tacaaaaaaa gttgtagaag tctttcaaga agcaaattta aatccgatct atagccataa
    63541 cgttcgttat tccatttggc gaaaagcttg tgtaaatgga acattgaatg gtttatgcac
    63601 gattttggat tgtaatattg ctgaactagg cgcgcaaaaa gcggcagaga gcatggttcg
    63661 aacaatcgta tctgaatttg cttctatcgc agcaaaagaa ggaatcatac tagatcaaga
    63721 agaagtgtac caacatattg cttctactta tgatcctgac aacatcgggt tgcattaccc
    63781 atctatgtac caagacctga tcaaaaacca tcgtttgact gaaatcgact acatcaatgg
    63841 tgccatttgg cgaaaaggac aaaaatatga tattgctaca ccatattgtg cctttttgac
    63901 ccaattagtc catgcaaaag aaggaatcct tggcgcagaa taaaaggctc tctgatgaga
    63961 atcagctgaa tcagcagctg gttctctttt tttaagccca ataaaagatc aaaaagaaaa
    64021 cacaactctc atgatgccat aagaattgtg cttgtttgtt tcagtacata atctcttcaa
    64081 aatgtaggtt ttttatttgt tttcaacaga ggagaggtca tattcgtatt gctcataaat
    64141 agtggaatcg ttagtgataa atcgttttgc ccaattttct gcatcataaa attccaatag
    64201 ctctgatagg attggcttaa atggtgtatg cagaaattcc ggtaattcat ctaaatcacg
    64261 ttctcgaagc aaaaaaatat tttcaggacg ataaaaatga taatgagcaa tcgcttgatt
    64321 atccgtcact agtttctttt gaaaatacat ggattcaaat gtccgcaaag tcactccttg
    64381 ctgaccctcc cgcaacagtt ccagaatccc gcgcgattcc cctgtttttt tcaggtactc
    64441 ttcataagta agatatccag gttgttcatt ccctcgatgt ggaagaatga aatagttggt
    64501 cgtaacatct ctttttataa attcctgctt atagctttct gctcgttctt ttctcccatt
    64561 attcgttgca ccaaaaaata gatccgtctt tggttcgcta gaagaaaaat tcatatgttt
    64621 cgaataaaat gaactattat gtttcagccc aagttctttt gcttccaaaa aatcaaaatg
    64681 ataaatctca tcgattgccg gttcatcttg tgcctgcttc agcatcgcct cgtgttctgc
    64741 tttgaagtga ttccaaaaaa ataacacaat ttttgcattg gtaaatgggc gcacgcgtcg
    64801 agccatctcc atatcaaatc cataatctaa aaaaacgatc agctgataat ttgccaactg
    64861 ttgtctagct gatttaatga attccgactg tagtaaatct tttccggacc aaacatctaa
    64921 agagcggatg gaaggcaaaa aataaagtga tttatttttt gcaactagca gtacgtcatt
    64981 tttgttcatc ttttccgcct cactttctct gtcacttttt cctatgatag cctgtttaaa
    65041 tagtaaaaag ccagtaaaac gtttcctata tttgtatgaa aatttaacat ttgtatgaaa
    65101 atatgatgaa ataaatcatt cttctattaa aattcgccta aaagttttct gaatagttgt
    65161 aattgtctga aaatttgtta tcattagtca ttgttaaata ttgctattta ttcttaatat
    65221 aaattttgat tgtgaattta aaagaaagag gtcatttatg gaagataaaa aattgaaaaa
    65281 acaacttagc tccagacata tcaccatgtt agctttaggt ggagcaatcg gtgcaggtct
    65341 atttaaagga agtggcgaag cgattgggat cgccggccct tctgtattga ttgctttttt
    65401 gattggtggg ctgattttat atatcgtgat gaaaggtctg ggaaaaatcg ttttaagcgg
    65461 tggcgacacg catcacggat tatctggttt gatacgccct tatctaggtg ctcattctgc
    65521 tgattttact gattgggtct actggtctat gtggattatc aatatcatcg ctgaagctgt
    65581 tgcagctgct tcctttttgc agttgtggtt cccgcacatt ccagcctggg tatttgtttt
    65641 tatgttggct gttttaacta cgatcatcaa tctttattcg gtacggttat tcgcagaaac
    65701 agaatattgg ctggcttttg ctaaaatcag tgtcattatc ttactgatca tttttgctac
    65761 ttatcttgtc ggtcagcaaa tgttgggcac aggcgttttc cctacccttc agcaattgac
    65821 tgaccatggt gggtttactc ctcatggtat gaagggaatc atcagttctt tgcttgtagt
    65881 tatctattct tacggcggtt ctgaactgat tgctatcacg gtaagcgaag cagatgatcc
    65941 taaacgtgcg attcctaaag caatcaaagg tgtcatggga agaatcattt ccttttacat
    66001 cattcctttg tttttgcttt tgattctttt tccttggaat actttagcag gcacgaatgt
    66061 cagtcctttt gtgatggtat ttgaaaaaat gaatatccca tttgcagcgg atatcgtcaa
    66121 ttttgtgatt gtccttgctt tgttctcatc tatcaattcg ggtgtgtatg catcttcaag
    66181 aattttgttc ttccgtttga aggatcgaaa aggttcctct agaaaactag ctgttttaaa
    66241 caagcatcaa gtaccgcaac gtgctgtttt attttgtacc agtgttcttt atcttggtgt
    66301 agctctttct tattttgtcg gtgacaaatt atttggctat ctggcaggtt ccctttcgta
    66361 tacagtatta ttgatctgga tcattatcag tgcggcatcc tttgtactgg cactaagaaa
    66421 aggaacatta tgggataaag gaatcagctt ttttgcatta gctgtcttag gattgatttt
    66481 ccttggtatc ctgttcacga actccattgg ggtaactgta ttgactggcc tgctttacct
    66541 gttcatttat ttcagttatc aaaaaaagaa tgatgcgttc gtattgacga atgaatgaaa
    66601 tcgatagaaa attttatttt atttatgtgg aatagatgga gctattgaag aaaggagttg
    66661 tgacaaaagt cttgttgcaa ctcctttttc cgaataaaca gtctcatgac ctcttggtaa
    66721 acggtgttca aaaaccctct gtgcaaaata attgattgtt ctccatgctc atgacatgat
    66781 agaagaaagg aatgaaaaaa aggagtttgt tttaaatgaa aaagtattgg aagtttttgt
    66841 tgatgatcgg tgtttcaacg gtagttatgt ttggtatgat gtacttgaat gtctatgcgc
    66901 tcgatcatat cttcttcagt cgtacacgag tattcatggc gttgatgatg ggtgcagtca
    66961 tggcagtcat catgctgttg ttcatgtgga aaatgtatga aaacaaaaag ataaatgtta
    67021 tgatcttagc cgctagtctt cttgtttttg ccggttcctt gtttatggta cgaagccaaa
    67081 ctactgtcaa cgacacagct tggatgaagg ccatgattcc tcatcattct atcgctatcc
    67141 tggcaagtaa acgagctgat ttaaaagatc ctgaagtaaa aaaattagcg gaagaaatca
    67201 ttcaggcaca agaagaagag atcgacaaaa tgaaaaaaat gatcaaagaa atggaatgac
    67261 cattatccgt ccaaataaaa aaagaggatg ttccagaagt tatcagcttc aagaaataag
    67321 aagaagctac ttctggaacg ccgtgaataa ggggttgtga aaaagctgcc ctgcatcaag
    67381 taataagaac agccaaacaa aaatagcttc tcctattttt cgtttggtta ggcttattac
    67441 cgcagatgca agcttttgaa caccgtttat taagaggttg taaaatcagc gttctgacct
    67501 gagtattaga gagacaaatg gaaaaatagt tcctcatatt ttgccatttt ttgagctaat
    67561 accgagggtc agctgattga acaccgttta tcgagaggtt gtgaaaaagt cgcttagttt
    67621 cgcgtattaa gaaaaatttt gtgaaatggc tttccacatt tttgtataaa tttggcttaa
    67681 taccgagaaa ctggcttttg aataccgttt attcgtaaaa gggattgtga caaaagtctt
    67741 gtcacaatcc ctttttatgt ttttattgtt ctaattgcgc tgtcttgctt actgcttctt
    67801 gcggtttcac aaattttttt gagattcccc aacctgtgaa ggcactgacc atcgaaaaca
    67861 caggagaaag caaactgaaa aatacgaatg gcaagtaagt gagtgtagga ataccaaatg
    67921 tacttgctac gaaacttccg gcaattcccc aaggcactaa gtagttgatt actgttccac
    67981 catcttctag cgttctacct aatacagttg gatcaaatcc tgctttttca taagtttctt
    68041 taaatgcatt accaggcaga ataacagata ggaattgttc accaataaaa atatttactc
    68101 cgatacttgt catcaatgtt gtaaaaatca aatttggtgt gttcgtcatc tttcttgata
    68161 ctcgttccat cacggttgag atcaagccaa attcgatcaa caatccacct aatgacaaag
    68221 ttagaataat caatgacaca gtaggcatca tactttcgat tcctccgcgg ctaagcagtg
    68281 aatcgatttg ttggtttcca gtatttgaaa caaaccctga ttcgatgacc ccagccaact
    68341 tcgttaagga agtttgtggg ttttgaataa aaatcattcc tactgctaca gcgatattca
    68401 acaaaatcgt taaaattgcc ggcacctttt tccatgcaca cagtaacatt aaaaataaag
    68461 gaatcagtga ccagattgaa atagtaaagt ttgcttctag aacatcagtc acttcacgaa
    68521 tagatgaaag acttgcggct ttacttgtgt gtcctaaaat catgaataaa aagaaagaaa
    68581 caacaaatgc cgggacagtt gaccacatca tatgcttgat gtgtttgaac aaatcggcat
    68641 caacaatagc tgctgctaga tttgttgatt cggataatgg agacatctta tctccaaaaa
    68701 cggcacctga aacaatagct ccaacaacca gcgctggatt taagcctagt gttgtcccaa
    68761 taccgaaaaa tgcaatccca atcgttgaca taacagtaaa ggcactccct acagcgctac
    68821 ctacgattgc acacacaaca aatacagaag ggacaaacca ctggacactg atcaatttga
    68881 acccaatgac cattagagtt ggaatgatcc ctgcttgtat ccatacagca atcaatgaac
    68941 cgactaaaat aaaaataaag attgggatga ttcctggttt gatgccattg atgattcctt
    69001 cgtgcagcca atctgtcggg tatcttttta tcactgcata caacatgacc attccgatcg
    69061 ctgctaagat cgtgatatta ggtgagacct ttaatccgac aacgccaatc gcaatgccta
    69121 aaacaataac cattaataca agtgttgctt ctaaaaaact tggtgttcct ttttttccca
    69181 tgataatctc tcctttttta gttgttctta tgttctaaaa aagttaagat atcggattac
    69241 tccgccgcaa ttcatccgcg attcctcctt tataaaaata aaaagacctg ttttaaacta
    69301 aggacgaatg actccgcggt accaccttaa ttaaaaacag atctgttttt cactttcaaa
    69361 cttttattca aatgtatgga ctttccatgt aattcgtcaa ttaggcttga tcggttcaca
    69421 gcgaccaccg actttctgaa caaaacacct aaccgctact gcgtgaaaag ttgacttgta
    69481 cgaagtttac cttccataag atcatttgtc aatgaaaaag aaaatatttt ttcatttttc
    69541 tgaaaattat ttttataact ttcacacaca agtttatttt ttactagaaa gtagcgccct
    69601 cttgtttttt tcttgctact atttcttgat gttcttgctt gattctttct aatagctttg
    69661 gctctttcaa cagatcaaga gctgtattgg cgagtagttc tgctgcaatc gcaatagaag
    69721 caaggccttt gtcactttta gcagcagctt tgaattcttc tgtgtgtccg gcaatatatg
    69781 tctcagagat tgctaccgta ggctggattg ttggtatgac ttggctgaca tttcctacat
    69841 cagaagaacc gagacttgtt ctttgttccg tttctatttc ttcatctgga acacctgctt
    69901 cttttgcatg ctggaagaat aagtcatcaa aagaaggagt aacgatgaca tcatcaactg
    69961 cattttggaa caatccaaac tcaaaagtcg tgcccgtact tatcgcagca cctcgtacga
    70021 tattttccac tttttcatat actttatcta atgtttgccg atttcctgca cgtaaataga
    70081 aacgtccagc agcgtaatct ggaatgacgt tggcagctac tcctccgtct gtaatgatcc
    70141 catggatatt gacatctttt ggcaattgca agcgtagagc gttgattcca ttaaacactt
    70201 ggatcaatgc ttccaaagca tttactcctt tttcaggtgc tgctgctgca tgggaagcga
    70261 caccgtaaaa tttgatgtcg actggatcat tcgctaaaga ttctgtcgtt ttcccataac
    70321 gaaaagctgg atggacgcat aacgctacat cgacatcctc aaaaaaacct tctcgaacaa
    70381 agctgccttt agctgatccg ttctcgcccc cttcttcccc tggggtgcca tatacacgga
    70441 tttctccacc agtttcatca atgaattgct tcactatgct ggcggctaat acggagtaag
    70501 taccaaacaa attatgcccg catgcatgac caatacctgg taaagcatcg aattctgcca
    70561 aaaaggcaat tgtgggaccg ggtttattgg aaatataacg tgcatcaaag gctgttcggt
    70621 gtccagctac ttctttttct acccaaaacc tttctttttc taattgttta atcaacgctg
    70681 ctgaggaata aaactcatag ttacttactt caggatgttc gtggatatct agagcaagtg
    70741 cttgatattc tggtaaacga tattggatta gatccttcaa ttggtttgtt gagattgttg
    70801 ttgtcataaa aaattcctcc tatgctagtc atttttctta ttttctcccg aatgtttccc
    70861 atgcaggcac gcttgatcct tttgatgttt tctcgattac tttgactgtg tcttctgttt
    70921 gataagcgtc tactattttt tgatacgttt tattgttttc atcttctttt cttgcaacga
    70981 tgatattcac ataaggacgt gcatggtcat ccactggttc taagaagatg gcatcagaag
    71041 caggattaaa tccagcatct acagctacac cgctattgat cactgaaatg tctacatctg
    71101 acaaagcacg tgctgtttgg gaagcatcta attcagaaat gtctagattt tttctattct
    71161 cggtaatatc agaaacagtg ggcgcttgtc cttttgcctt atccactttg atcaatccag
    71221 cagtttgcaa taacagaaga gctctgccgc catttgtaac atcattaggg attgctactt
    71281 ttgctccgtc tttgatatca gctacatcct tcaaagtgtt agaataaatt cccagcggtg
    71341 cattgacagt atttccgatc gatactaaat cagttccgtg ttctttattg taattgtcta
    71401 aaaagaattg atgttggaaa gaattcaaat caatcgatcc atctgctaaa gccacatttg
    71461 gttgattgta atctgtaaat ttcacgtatt ccaaattaat gttctccttt ttcaaacggt
    71521 ctttcacgtt gtcccataca tctgtatctt ctccaataat ccctagtttt acgatagttt
    71581 cttttttgtc agttgtatct gcttttcctt ggctacaccc tgccaaccaa ataattgcta
    71641 caaatgtaat gactacaaaa cgaataattt ttttcatttt ttctcctcca ctttcaatgt
    71701 gtaatttttt taatcagttg attactgata aattgactta aaaaaactaa gattagaatc
    71761 aataatgtag ccacaatcgt tacatctgtt tggaatcgat tataccctct cgatatagca
    71821 agattcccta atccgcctgc acctactgct ccagccatgg tagtcagtcc gatcacgttg
    71881 atgatagtca acgccgagac ccgaatgata ccaggcaaac cttctaacaa atacacacgt
    71941 aaaatgatac cgattggact ggttcccatc gcttctgccg cttcgatcac cccaggatca
    72001 acttctagca gtgcgttctc gatttgacga gcaaaaaacg gaacaactcc aaaaatcaat
    72061 ggcactaaag ctgctttcgc accaatcgtc gttccaacta agaaacgagt agtcaatgct
    72121 aaaagagaaa gcaagataat gaaagggatg gaacgaatga tattgatcag cttatcaagt
    72181 atttcaaata gcagacggtt agctagtaat ccattagggc gtgtcactac taacgtcaca
    72241 cctaagatga ttccaatcat cccgccaatg aatgctgtcc aaaaagacat atatagtgtt
    72301 tgcttcgtcg cttcgacaaa ttcatccgga atcaaataaa cattgggcaa atatgtttta
    72361 aagaaatcag tcattttatc ttcctccttc gatcactttg atacgactat ctaaatcgtt
    72421 tttttgtaaa atatttattt ttacaccaga tttgatcaaa taatccaatg cttttttccg
    72481 ctgtttggtt tctccagcta aagtaacgat caaactccct aacggcgttt cttgtaataa
    72541 ctctacattg ccatataaaa tattcgctgt tacttgatat ttgctgtaca gatgagcgat
    72601 tagaggttcg ttcgtctgat ttccaatata acttaattcc accagccatt tattggcgat
    72661 ctgatcggca aaagcagaat gggcaatgat cgtttctaat gcttggtcaa gatgagtagc
    72721 tgttcgaata aaatctttgg tcaattcttc ttcaggattg ctgaagatct ggatgctgct
    72781 acctttttca acgattcttc catcttccat aaccgctacc ttgttgcaga tttctttgac
    72841 aacttgcatc tcatgagtga tcaggacgat tgttaaacct aactggcgat tcaatttttt
    72901 taacaatgca aggatctgaa gggtcgtttt cggatcaagt gcactggttg cttcatcaca
    72961 taataatacc ttaggttcat tcgccaaagc tcgtgcgatt gctactcgtt gtttttgtcc
    73021 ccccgacagt tgtttaggat aagcagatgc tttttcttcc aaaccgacaa gttccagtag
    73081 ttcattcact ttttgacgac gttcctgttt cgattttcca gaatacttta aagaaaaatc
    73141 aacgttgtca aaaatagttc ggctttccat tagattgaaa tgctgaaaga tcataccgat
    73201 ggcctttctt tcttttcgca attctttggg agagagctga ctcagattcg tctgattgac
    73261 aatgacttct cctgctgttg gtttctgcag caaattcatc acacgaacta acgtactttt
    73321 ccctgcacct gagtaaccga cgattccata aacatcgcct ttttcaatcg ttaaatctac
    73381 agaatctact gcctgtatct ctttttcttt ttgtttgaaa catacagaaa catctcgcaa
    73441 ttcaatcatt aaaattcctc cttatctaaa aaaagcgtcc tcaagaaaat gaaaatgtca
    73501 ttttcttgag gacgcttttt tgcgtgttac cacctcatgt tcaagctgtg ttcacacaca
    73561 actcctcttc aagtacgatc atactctagc aagatatcgg tcgcagccgt catcgcctta
    73621 catctatgct cgggatgaat tgctcgatgg ccattttcca atagtcgttc cttgcttctt
    73681 ctcagctacc gaagctctct gtcaaaggtt cttctatcgt acttaccatt tcaatgcaaa
    73741 taatattcaa aaaaaaagtc cttttactaa cataaactat gtcagtaaaa ggacgacgta
    73801 tcgcggtacc accttttttc ggaagtttcc ttccctcaag cccaacatct caaaaagaga
    73861 gattggcgtt cgttttaacg gtcgaacagt tccgaatttg cctacttatc gacaaattat
    73921 tctccaaggc cattttcagc ttttcttact tgactcttct caccagccag agcctctctg
    73981 caaagtttcc aaacttactt tccttttcaa cgaaatcgat attttgttgt tgggattaat
    74041 ctacatgagg aaaactgaaa agtcaagtac gaaattcaaa ttattttttc tatatttatt
    74101 tttctgtttt tttatttaac atttcaataa cagttcgaag atcttttcct tccgcaagaa
    74161 gtttcaattt ttccttttct tcgacggtat aatttcggac aaaactggaa tcaggtatca
    74221 aaacaacgcc taatcctgct cgtgaagcag ctgttgctcc tactaaagaa tcttccactg
    74281 caaaggctga actagcttct aatcctgttc gttccaaagc tgtcagataa ggaatcggtg
    74341 aaggcttgtt ctccgacact tcgtctccga atgtaaacgt gtccaagtaa tcagctaatt
    74401 taaagtgatc caagatatct gttgctcttt tcgtaacagt ggtcgtagca atgcctagtt
    74461 tcatatgacg ttcttttaag tctgccaata tttcttttgc atatggtttt aagtggatgg
    74521 ctccgcttgt cagctgttga taaaaatatt cttcacgctt cgctcggact tcctgtactt
    74581 tttcagggct acctgctgct ttcactaaaa tatcaaaact ttgtttccag ttttttccgc
    74641 cccaagcgtc aacgatttct tttgggatat ggatatcaaa ttgctgaaat ccccaaagcc
    74701 agccatcacg atacgttttt tctgtgtcaa ctaacaaacc atctaaatca aatattgcac
    74761 ctttcatcta tacattaatc ctttccaaaa caatacacat agtttagcac gactggtcca
    74821 aaaagaacag aagcaaagaa ccagccttct cgtttataag agttcttgga atcgacggat
    74881 atagattttc ttcacagctg tcacaagcgc cagataagcg atgactgtag caaataacca
    74941 taaccagtaa ttgccaggaa gtggcatcaa gcctaattca gcaccaaaac ttgtaaaagg
    75001 aaggacagaa ccgacaataa ttcctaatgt agtgataaca aacatggcaa atgttgcgtt
    75061 gctttggata aatggtactt tcggtgtacg cagtgcatgg agcactaagg tttgtgtcca
    75121 tagtgattcg acaaaccatc ctgcatggaa taatgcgatg aaaatcactc gctgtgaact
    75181 atccaatgta tggaaacttc cgcccactac agcaggacaa ataacaaaat acatcaacaa
    75241 gtaagtagta atatcaaata tcgaacttgt tggaccaaag taaaccatga attccccaat
    75301 actagatgca ttccattttt ttggctcgtc caaatattct ttatccatcc gatcccatgg
    75361 caaggaaatg caggaaacat catagatcag attcaaaaac aaaagttgta aaggcagcat
    75421 tggtaaaaat ggcaggaacg tacttgcaat cagcacggaa aacatattgc caaaattaga
    75481 acttgctgta gccttgatat atttcatgat attcccaaaa gtttctcgtc cagaaagaag
    75541 gcctctttcc aaaatcgtca aatctttttc taaaaggatc acgtctgcag attctttcgc
    75601 aatatccaca gctgtatcta cagaaatacc gatatcagcc actttcattg caggagcgtc
    75661 attgatacca tctcctaaaa atccgacagt atgaccattt ttacgtaaag ctgtcgtcaa
    75721 acgtgctttt tgctgaggat tcaattttac gaatacttca tggtcttcag ctacttgtgc
    75781 taattcatga tcactcattt ccgagatttt ctcaccggta accaattcat tgatctctag
    75841 acctacttga cggcacactg aacgtgtaac taattcgttg tccccagtca gaacttttac
    75901 agctacacca tgttctttca gagctttcaa cgcctgtttc gttgtttctt ttggtggatc
    75961 aaggaaagca agataaccaa tcaaaaccat gtctgactca tctttgactg aaaattctcc
    76021 aacgacgctt ggattggtct tttgtgcgac accaatcact cgtaagccat cttcattaag
    76081 tgactgtact tttgcaagta cggcttcttt tcgttctttt gttaatggtg taacagtacc
    76141 gccaagatca ataaatttag aaatgttcag catttcttca atcgcgcctt ttgtgatcat
    76201 ttgtgtttta ccagctggat cagcaaccac aacactcata cgacgacgtt caaaatcaaa
    76261 aggaatttca tccacttttt gataattgat cttatctgta tctaaagttt ctgttgcttc
    76321 atcaatgata gccacatcta acaaattttt cagccctgtt tgatagtagc tatttagata
    76381 cgcatggcgc aaaacacgat catcttcatt tccttcacaa tccatatgat attcaagaat
    76441 gattttatct tgtgtcaatg tccccgtttt atccgtacat aacacatcga ttgcaccaaa
    76501 gttctggatg gcattcaaat ttttgatcac tgttcctttt ttggccatca cacttgctcc
    76561 tttgaccaaa ttcgtcgtaa cgatcattgg aagcatttca ggtgttagac caactgctac
    76621 agatagtcca aaaagaaaag cttctagcca atcccctttt gtaagcccat tgatgacgat
    76681 aactgctgga gccatcaatg acataaattt gatcagtagc atggatgttt tatggatgcc
    76741 taattcaaag cttgattgaa ttggtttttc agatagcgtt tctgctacat gaccaaatag
    76801 tgtttcattt ccaacagaaa caatgattcc ttccgcactt ccactgatga cattacttcc
    76861 cataaagaca agattttcgt aacttgtttc gctttgctga tcgtcttcac atactttcgc
    76921 atgcttttct actggatagc tttcccctgt caatgctgct tgggaaatga ataaatcctt
    76981 tgcggacaat aaacgcatat ccgctggtat catatcccct gctgaaagcc gaacaagatc
    77041 tccacagacg atttcttcca taggaatctc tgtgtacttt ccattacgtt ttacagctgc
    77101 cgttactttc acaagtgatt tcagtttttc agccgcttga ttggaacgta cggactgaat
    77161 caacgtcatt gtcccgctga cgataaccat agtgaagata atggctacac cgaaaagatc
    77221 tttatctcca ggagctgcta atacatattc cgtgatgaat gaaataattc ctaatgcgat
    77281 caacactaat gtaaatggcg tgatgtatgc tttcaatatt tctacaatga atggtgtttt
    77341 tttgccatat gaaatcgcat tttcaccgta attttctctt gaacgttcga tttgttcttc
    77401 tgtcaatcca tttgctgatg catggaatag ttcaaataat tcttgtttcg tttttccagc
    77461 aaaagctgca tagatttttt gtgtatcttt ctttttttcc atctcaatct ctcctttgtg
    77521 tccaaaagac agctgttctc gctgcttttg gtctttagct attcatcgga tcgatagaga
    77581 aaaaactgaa aggggctgag aacagataga taatagccct ggcctttcct ctagatcctt
    77641 gtttttcgaa tgactgtcat ccatttgttc tcatctcctt tactaagtaa ttttaattca
    77701 tgacttccaa tcatttttcg aatagttatt tttccaatta gaccacctcc tttttatttt
    77761 tcaccgatgg ggatttgcgg caacaaaaaa acctctcgcc aaatactcag cgaaaggttt
    77821 gaaaaagcat attaaaaaaa gcttctcaga tctcatcgtt gagttttgac actgtacaac
    77881 gtaaaaagca gatacctgct tttagctacc ttatgaaaag ccttatctcg acaattcctg
    77941 ttctacccat tggcgtctct cgacgttttt gggcagtagc ctatgtttgt ataggagcct
    78001 cacctaacaa atcttattcg gttttccttc gttaatataa caactaaaaa agaggatgtc
    78061 aaatcaattt tccatgtttt tcatactttt tttaaaatac acacgttata ttcctgtctc
    78121 acgcggtttt atttgtctca ttttccacct cccgctataa tagaaatata gtaggaaacg
    78181 aggtgctgtt atggaaagaa cacttgttat tatcaagcca gacggcgtga gacgccattt
    78241 agtcggaagc atcatccaac gttttgaagc aaagggactg gccattgctg aaatgaagtt
    78301 tgaaactatg actcctgaat tagcaaaaga acattatcag cacttgactg agcgcagttt
    78361 ttttgatgaa ctgatcgatt acatgacttc cggtcctgtc gtttatcttg tgctggtcgg
    78421 cgaggaagtg atcgatatcg tccgtaagat ggttggagca acaaaagctg ccgatgctgt
    78481 tccaggtacg atccgaggag actacgcgct gccggggact gaaaacatca ttcacgcttc
    78541 tgattcccgt gatgctgcgg taaaagagat cgcccgcttt ttcccgccat tcgatataaa
    78601 caaaccgtct gaaaaagcgg cgaagtgata caaattctaa actgctggtc tagttgctgg
    78661 gttcagcaat ggccagcagt tttttctcta aggacctccg ttgattcttt cctaacatat
    78721 attcgagcac tgtgaagaat tcttggtagt ctttcgtctt ttcttcccct aaagcagcag
    78781 aaatcaatct ttgataataa tctgccatca atgtttcata gatcactgta cttctttctt
    78841 tatgtgataa gctccgtttc atatcttcat tcacactacg tgcctttttc aaccgaccat
    78901 tttctatata aaacgaagtc aggttcatta aaaaagtaaa gagatactgc tcatgattgt
    78961 tcaactgtgc taatcgtcgc attctttttt tgattttcaa ataattgttc tcaatgaacc
    79021 gatcactgaa tatccaagga aaatcagcta gaatagatag ttcaaattga ccatagtctg
    79081 gtatctgcat caagtattct tcaatgattc ggcattcata acgtaaaaat tcaaattctg
    79141 tctcagatac ttctgttttt tcgaccatgt gaagattcaa aaccaaataa tacagatctt
    79201 ctgttttctt aaaatgccta cggttattgc tgatctcttt ataaggatca aagctgtctt
    79261 cttgtacccg atctagcatt cgtctttttt tctttaactt tattggttca tccagctggt
    79321 ttcgcatcca ttcatattct gcaagtgtca tgttcattcg ctctaaaaat gatctcaatg
    79381 ttacaaatga catttttttc actgaatttg tctcaatccc gactagagaa gtcttaaaac
    79441 agattccttc cgctaattgg gactgtgtca acttcttgtt gactcgaagt ttcttgatca
    79501 attcaccatc atacataata gttctccttt ttaatttaaa tttttccaca ttcaataaat
    79561 agatacgtta aaaaggaaaa atacacgaaa aaaataaaaa aatgtttttt tcataaaaaa
    79621 taccaacctt caagcattag aatgttgtct aactactgaa ggttggtttg attgtttatt
    79681 gattattttt ttgctgttca acgtctgttc ttgttactgg atataagttg gttgttgttt
    79741 tattaccatt ttttgaaaag acacttgtcg aatgttcgcc tttttgcttt tcgattgctt
    79801 cattacgttc cgcttcattt ttatagtcat attttttcgg atcaatcgtc tcaaatccgt
    79861 ttggcacata aaaccgcaag agattttcct gattcagctt atctgaaaga cttaacgcag
    79921 tcttgacttt ttcctgatct ttggagattt cctcatcgat tcctgctgct ttcgtatcga
    79981 tgatttctcc tgtctgatta ttgtaagctt ttcctcctag gacggtgtat ttgggtgtca
    80041 caaagttccc atttcgaaaa gcaactactt gatcatgctg agaagataat aagtctgtac
    80101 caaaatgaag ataatcttta tcatcgattc ccaatagatg tagtaatgtc ggcaaaacat
    80161 cgatttctcc accgtattca tgattgactg tccctttagt ataaccaggc atatggatca
    80221 tcaatggcac tcgttgcatc tgtgcgttgt caaattcatc ccatgtatct ggatctttac
    80281 caagagcgct tgctaaatct ttattatctg tattcgagat cccaaaatga tccccgtaaa
    80341 tcacaaagat tgaattttgg taaataccag attttttcaa atacgtaaaa aattgttcca
    80401 atgattgatc cagataatgt gccgttcgaa cataattatc tactgtgcta ttgccagtat
    80461 tcaaagatgg aaagtcgaaa ttcttgtcat ccgtataata aggcgtgtgg ttggttacgg
    80521 aaagaaattt cgtgtaaaac ggctgttgta gatgctcaag atattgggca gattctctga
    80581 ataaatcttt atctaatatc ccataaccta acgtttcgtc ggattcatca aaataagatc
    80641 gatcaaagaa attgtcataa cctaagtttt tatatacatg atctctattc caaaaactag
    80701 ctacattccc atggaaaaca gcgcttgtat agccttgctt ttgtccaagg atcgctggtg
    80761 cggcttgaaa gacattgtct gacccaagtt ctgtgaataa tgagccttga ggtaaaccaa
    80821 atgtgccagt ttccaacata ttttcagcat cacttgtctt tccctgtcct acttcatgaa
    80881 agaaattgtc aaagctgatc gttgcttgat tctggaaaat actatttaaa aacggtgtga
    80941 cttcttgtcc gtctaccttc atattaatca aaaactgctg gaaactttct aaatggagaa
    81001 cgatcacatt tttcccttta gcgatcccaa atgtttcggg atttggctct gcataatgtt
    81061 tctttgtata atctaaaact tcatcaatcc cattactgct tgcatgcgcg cgaacactgc
    81121 tagtcattcc tgttttgatt ccgtcataaa tagtatacgc atcgattcct agatatttga
    81181 caatatatga acggtcaaat gttcgctgca gcaattgtgg acggttggct tcgctcagcg
    81241 ctagatttcc tgaaaaaata agccctgaaa gacaggtaac agcgatagcc atcggtttgc
    81301 cgacagggtt gcttttgata ggtattttct tgaccttcaa ccaaaccagt agcccaatga
    81361 acacagcgat atccagccag tagatgacat catggggctt catcaaagaa aaggagcttc
    81421 ctgacaatcc ttgcgacact ttcgaaaagc ctaatacaga tttgactgta atgaaatctg
    81481 tgaattcccg ataaaaaata atattcaagt acaacaaaag cgtatttaaa atatcaatga
    81541 tcaaaagaat agctaacgct ggctttggct ttttaatata caaagaaagg ccaaaaaaca
    81601 ataaggtagt cgcaattggg ttgatccaca agataaagta ctggatcgta ccttccacac
    81661 ctaatgaaaa atctgcatag taggcaatga tcgtcttcag ccagaaaaag aaaacagctg
    81721 tcaaaacgat tgctaaacga ttttggcaca tttttttaag ttgtgtcacg tatatcactt
    81781 ctctctattc acattttttc ttattttgct cctgaaaaat gaaaatttcc taaaaaagtt
    81841 gttatcttaa gattttttta ttctttctaa agattattcc gtccactttt cacagcataa
    81901 aaccgctgcg atgtaagcga ttaaactaat gaagagataa aagtcttgtg gtgaccgctt
    81961 cactccacgg tattcaaaag ccagtttctc ggtattcgta caaaaaaaga ggctgtgaca
    82021 aaattcttgt cgcagctcct tatttcttga tgcaggacag ctttttcaca acttcttcct
    82081 taaacggtgt tctcctgcca actcctcggc cacaagtcac aatatttata aaacatgaga
    82141 agctgttttt tgaaattgtt ccttgtggct cagagttaaa cggcaggctc aagacctctt
    82201 gatacacggt gttcaatcag ctgaccctcg gtattagatt atgtcaggac gctaatttta
    82261 caacctcttg gtaaacggtg ttcaaaagct tgcatctgcg gtaataagcc caaccaaacg
    82321 aaaaatataa ggagctattt tttgaaattg ctccttgtgg ctcagagtta aacggcaggc
    82381 tcaagacctc ttgatacacg gtgttcaatc agctgacctt cggtattagc tcaaaaaacg
    82441 gcaaaatatg aggaactatt ttgccgtttg tttctctaat actcaggtca aaacgctgat
    82501 ttcacaacct ctgtttttca ttgtccatag gattgatatt gtccttgtga tgactcattc
    82561 gtaataattg aggcttgatt ttcttcactt cccgttatcg tttgtccact gccagaatct
    82621 gaaggacttg ttcctgtcga ctcgtttttt tgagaagaga cagttgtttt cttgacttgt
    82681 tcatttgtct ttttccattc cgctaaacga tcggcgacca cttttttgtc tactttttca
    82741 gaataagcgg tgatcacttt tccatttttc aaacgggcta ctttgtcgcc atcatgagtc
    82801 aaaagcaaaa cggtcaaatg cttgtcttta aattgatatt gtctgagaga aatcgcacta
    82861 agtacgtcat cgatattaat aaattgattt tcttcttttc cttttggcaa ataaatgtcc
    82921 aattcgcctt tttcgtaatt ggcagttatt ttatactccg cccaccaata agttgagaat
    82981 tcttttttga aattatctac tgattctttg cttgctacga ttttttctgt ttctttctga
    83041 gcaagatctg ctgtcatttt tcctgaaaat gctgcggata aaataagcag taagaaaaaa
    83101 ccgaataacc aaaagagaag aaacggtctt tttttcctca tgctttcctc cactcctatt
    83161 taattttgac tattctatta tatacaaaaa atgaaataga aagacaaaaa agttgaaaaa
    83221 gatcgtaaat aattgaactt ctttttcaca aaatggtaag aatggagaat ttcacgcatt
    83281 tgctctcaac tattctttct taagcctcaa atccgttttt atctgatacg tctttgaacc
    83341 aatgacccga ttttttgatt gttctttttc catcttgtgc taagtctact gaaataaagc
    83401 catatcgatt cttatatgca ttggtccacg accagttatc catacatgtc cacatatgat
    83461 agcctaaaca attggcacct tcttgaatgg cttgatggac atatttcaga tgagattgga
    83521 caaattcgat ccgataatca tcgtggatca tgccatcttc tttgataaat cgtgcttcgt
    83581 tttctacacc cataccgttt tcagaaataa agcagtcgat atttccataa tgatctcgta
    83641 cattgatcaa aatatcatag attccttgtt catagatctc ccatccgcga taaggattca
    83701 ttttacgacc aggcatttca taattgtcga aataatcctc aggcattgga ccgtttttag
    83761 tatcgattgg tgtttctttt gcttttaccc ggcgtggctg gtaataattg atacctaaaa
    83821 gatctactgt attttctttg ataaccgtca aatcctctgc atggatcaca ggcatgagat
    83881 caagttcttt tactatctca atcaattcac ttggaaactc gccttttaca gctggatcaa
    83941 ggaatgaacg attgaagaac gcatctgcta tttgcgctgc tttaacatct tcagggtttg
    84001 attcgtctct tggatagctt ggtgtcagat tcaagatgat accaataaca ccaccttgct
    84061 ccatttcatg gtaagatttg atggctaacg ctgaagccaa cgcttcatga tagccaactt
    84121 ggatcgcttt tttcatatct gactcttctg gataatgcca tcgatataaa taacctgctt
    84181 cgactggaac gattggttca ttatgagtaa accatttttt tactttcgaa ccaaacaatt
    84241 caaaacaact tttggcatat ttttcatagg cttcaaccgt ttctcggttc aaccatccgc
    84301 ctttttcttg cagatacatc ggcatatcga aatgatacag attcacaaag ggttcgatac
    84361 cgttttcaat caactcatca aaataacgat gatagaaacg aacggcttct tcgttgattg
    84421 ttccagattc atcaggtatc aaacggctcc attggataga tgttcgaaat gaattatgcc
    84481 cagtctgttt catcaactgt acatcctctt gatacttcgt ataaacttgc gaggtttttt
    84541 caggtcctac ttgatcaaag aacttttgcg gttctttttt gtaccaataa tcaaaaatgt
    84601 tctctccttt tccatcgcct gaaatccttc cttctgtttg tgggccactt gctgcagaac
    84661 cccaccaaaa atttgctgga aattgatatt ttttcatcaa agcacctctt tttctttttt
    84721 agttcgtttt agttgattcc atgtatgata ttttccatca caatcacttt ttcattttct
    84781 tcctcttctt ttttgattcg ttttaacagc tgttctgctg ctcgttcccc gattttatct
    84841 gttggtggcg tgatcgtgat tttcggaagg atactcagat cgtttttatc taaataatca
    84901 tagtgactga acgcaatatc cttcccgatt ctgacacctt cttgattgaa acattcgatg
    84961 gcaccaatcg acatattgta attgctgaca aaaatagcag ttgccccttt ttctaataat
    85021 gcttttgccc cgtaatagcc gctttttcta gaatagtctc ctgtaaagac ctctaattgg
    85081 atcgatggat cattttggac cgcttctttg gctcctgcta aacgttctct tgctacgtag
    85141 tctgtttgag tggcagcaat aaatccgatt tttttatgtc cttgttcacc atgatgagcg
    85201 atcacttttg ctacactttc tcgatcattc actaatattg tatcaatacc tgctggtcct
    85261 tctggacaat tcaatgcgat aactggaata ctcatttttg tgagcatttc aaatccagac
    85321 cactcttctt cggataagaa gacaatcagc ccatcgatca catgcttcat caggtattca
    85381 attttttgtt caattttttc tggctgatcg gcaaacccgc ttaataataa gctataccca
    85441 ttttcttcag ctactctttc gatccctgag acaacttccg acccaaaacg gctggaaatc
    85501 ccgtttatca aaagtccaat agagaagctt cgattattct tcaacccttt agcaatgatg
    85561 ttttctttat agtccaacgc tgaaatcgct tctgctattt ttttcatgtt cttttccttc
    85621 agttgctgac cattcaagta acgggaaact gttcccactg aaacaccagc catcttagcc
    85681 acatcacgga tcgatgccat acattctcac tcctgccagt tacatttgat ttctctttct
    85741 tgttgttcga ttatgatgac cgcattcttt gcatagtgtt gcttgtcatc aatatccata
    85801 taactaaagt cttcagtaga gcaacttcct ctcactatta attatactta aacaagtatt
    85861 tgaaccggtt catttttaat atagcatttt tttaaaagat tgcaacactt ttttaaaacg
    85921 ctttctgaaa gtggcggatt ttttgccttt ttaaaatttt attctaaaat ttactctatt
    85981 tgtgggtgtt ttgtgcgttt ttctcttcca tccgtttgaa gttttacatt ccaatggtat
    86041 aatttcttta tcctatcaaa tgggggaagt attttgaaga aattaatcgt actatttatt
    86101 ttgtctgcgg gacttttgac attgactggc tgtgatttgt ttggcggctc tgaccaatcc
    86161 tcggacgaaa caaccgattc ttctgtctta aaagcggaaa aagcagatac caccaacagt
    86221 gtatatacgc taaaagtacg taaagatatg gatttatccg cgggacagtt gacatttaca
    86281 gataaaaaaa tggaatggac acgcacgtat cagacacaag gaactgattc ttctgaatca
    86341 tctgaagaaa aaacagtgct gacagatatc aagatcacta ccaaagatga cgaatatatt
    86401 atttcaggaa aagaaaataa aaaagaaaca acagtcatat ttacaaaaat cggtaattac
    86461 cgtttgaagg atgaggatgg caacatctac agtctatagt gccgtctgtt ggatcttctt
    86521 ttgtttctcc ccttcttttc tgctatagta aagaagcaag atgattgtaa aggagacgaa
    86581 atggatgatc gatagtcctg attattgtac atgtaataac aacaaaaata tccatacaga
    86641 atttaatgac caaggaagct tgagcatatg cgacaactgt cacaaactag tcaaagattc
    86701 atttaaaaca tttgaatctt atcctgttca aaattatgta aaaagtagaa gaagataaac
    86761 aaatccaagc aaaactcact atggctgatt tttatgaact tcaaactcag cttcttcctt
    86821 tgatcaagct tcatcagtaa aacaaacagt ggatcatttc agtttacaaa tcaaagagta
    86881 aagatttatt tatttcaaat atttgaatat aaaataacca aacgatagaa aggcttattc
    86941 tacatcacgt agtaattttt ctttcccgtc gtttggtttt ttatttttag cctaattctt
    87001 gaccttttgc atgctggtta tccgtaaaat attttccagc aggctttcct tccaattcag
    87061 ctaatttttc ttggatctga cggatcacct tttttgcatc ttctggattt tctacaaaat
    87121 cgaatttatc cccatccact tgtattttag gacatacatc aaaatcttca taccattgat
    87181 tatagcgggt gttcaacgtt tcataatagg tatataacgt ctcatcgctt tctagctgtt
    87241 catagtcacg cccacgtttt ttgatacgtt ctagcatcgt gtccaaagaa actttgatat
    87301 ggaccatcaa atcaggccgt ttttttggag caacatcatc taactcgttt agcatcgtat
    87361 ctaataagct atcgtactgc tgtacttcga tatccgttac ccgacctaaa tcagcgttta
    87421 gatggaacaa caggctatct tcatagatgg atcggtctag cacattgtca tcgttcacta
    87481 aagcattttt cattgctaaa aatcgcttgt tcaaaaagaa gatttgcaat aaaaaagcgt
    87541 actgctcagg atttgaataa aagagcggca atacttcgtt atcttcgaca ttttcataaa
    87601 atggtttaga atcaatctct tttgcaagca tatccgtcaa actgctctta cctgcaccaa
    87661 tcgttcctga aatcaaaatc actgacatac aacccttcct cttctataag tactcgccta
    87721 cgtaagtttc aacaggcaat gtttcaaaat catattcacg tacagcttgg tctgatttta
    87781 aatacgtatg gagactttgt gtaatcatca agttcgtagg taccgtctct tcttgtacaa
    87841 tgatcatcgg ttttttcaac atagttgcca cacctaattc gtaagccgtt cctggatcga
    87901 ttgtttgatg ctcaaagtca aggatagcaa caacaaattc tgcatttgtc agttcttcca
    87961 tatctttttc gtatacttcc tgcgcccatc cagcgctgaa tagttcataa ttgctttctt
    88021 ggtgatgacg tggagagtag aaacttgtga ctgttttgtt ttcctccaac gctttttcga
    88081 tacgacttac tcgatcgatt tgctcctctg aaaaaaatgg tcctgctaaa tatatttgac
    88141 tcattatttt gcctccttca ataataactg atttttaata gatactgctc gtaattcatt
    88201 gaccagttcc aatggattgt tggaaaagat tacttgatcc aaccattttt tatccataaa
    88261 atcctctttt gcaaaagttt ctaataattg ttgcaagccg ctgtaataac cgccaatatt
    88321 caatattccg attggcttgt cgggcgtcag accgattgct atccaagaaa gaagttgtga
    88381 gaattcctcc aatgtaccta gacctccagg gaaaacgagg acagcatctc ccttttcaaa
    88441 taataatacc tttctttcat cgatcgtttc tgtaggaata aatgtagtaa catcttttcc
    88501 aggcaattca gtttcaaaaa gcccattcgg atagatacct gtgacttttc cgttattttc
    88561 cagtactgtt ttactaatca ctcccataat cccggagtat gaaccaccgt aaaccagttc
    88621 gatttcttct tgtgccatgt attttcctaa cgtttgcgca ataaatttgt aactttcttt
    88681 attaccaaaa cgggaaccgc aaaaaacagt aagtttcata aaaaaacact ccctaactca
    88741 aaagtctatc ttcattctac acgtgttttt ttaaaataaa agactagatt ttgtagtttt
    88801 ttagtggtat ataggataga cgccactata tatagtattt agaaaaaaat catttttcag
    88861 ccattttata gataaaacaa aaataaataa cgtgttttca tcgatatgaa atgacttact
    88921 tatagaagat actgggattt cgtcctatat gccaataacg tgtattattt taaacaacaa
    88981 atacttgttt cttttattaa cgaaaaaatc attttgttct cgtgttatgt ttcactgata
    89041 aatgatgttt ctctaaataa aaaagccgac gaactaaacg atcaaaattt gatcattttt
    89101 gttcatcagc ttctcctaaa aatctttttg ttaacgataa atagctggat ttgtaaaaat
    89161 atcacttgaa tcgtcactgc tggaagaaaa ttcagtgata accgcacctg ttgcgcctgc
    89221 ctggaactag tgtttgatat tgggctcgaa cgtgtactga tctctagcat gaagaataat
    89281 ttcttttttt actgtataat aactttcttt cctttttgga atagtacagg aaagtttttt
    89341 tgtttccttt ccttcgacat aaggtatacc agaccctttc gacaacgaaa ggttctcatt
    89401 tttccttcat cgtcatttca aggagggtgc cgatgctctg gacagtttcg atcgctccta
    89461 aaccaaaatc tgtatattcg attctttcta actctgattc tttcatacca ttcctgtctc
    89521 aaggtacatc tattgtactt ttttcttgta atccattctg cctctcctaa ctaattgtca
    89581 aatcatccca agatatgtct tcttcctctt tttcttcttg gatgatttct gcattcggat
    89641 ctactggttt tttcaataat aaaatggtta ttcctgtgac aaaagaacca gctaacaatg
    89701 caccaatgaa tgcccatggt ctggtcatcg tagcgactgc aaacattccc gatgccggaa
    89761 tacggctatc tgcgccccaa aacatgctta atccgccacc tactgtccca ccgactcccg
    89821 ttgctatgac attgcgtgcc aagtcgttca atacgatagg gaaacatccc tctgtgatct
    89881 gacagatccc cataggaaaa gcggtcttca atgtatcgat ttcttgacga ttgagtatat
    89941 ttttacgaat gattttccct aagaaataag cgatcgtcaa gccgaatggg gttaccatcg
    90001 aagctaaaat caatacagtg attggttcat agattccttc tgaaaatcgt gccacacccc
    90061 cttatccaga ataaatggta atccagaaac agccgtgtat ctgcggtaat aagcctaacc
    90121 aaacgaaaaa tatgagaagc tatttttgtt tggctgttct tattacttga tgcagggcag
    90181 ctttttcaca acctcttttt ttatttatgt ttcataatca atatggtaag gatgcagctc
    90241 cgtatggtag accgcctccg aatattcaat catttcccca atttgcgtag acgatttccg
    90301 tatccgtttg atgccgatct gtgcgtctgt tttcagaatt ccttgttctt cttctgttaa
    90361 aaatactgcc gagaaatcat cagaaaatga gtcaatagta tatccttttt tcgtcagcaa
    90421 acgatacaaa gattctttgc caaattcttc tctgctgaat tgcatcattt cttgtggaag
    90481 ataatgaaca aaataaatat aaggctgatt gttcaaataa tataagcgct taaaacaaac
    90541 agcttgctca ccgaaaaagg aaaacaaagg atcttccttc tttatatgga ccaattgcaa
    90601 atccagcgtt tctttccgga cttcatatcg ggagttctcc aagatttgcg taaagcttgc
    90661 cgctttggat aatcgattgt aaggacgatt gcttagaacc gtcgtcccac gaccactttt
    90721 ctttgcgaca tattcatctg atgccagcag ttcgattgcc tttcggacag tgattttgct
    90781 gacttgaaac agttcttcta attcactttc tgtcggcaac atcgaaccga ctggatattt
    90841 tcctgagaaa atatcttctt taattttatc tgcgacttcc aagtatagta cacgtgtcct
    90901 tttcataacg tcaccctttg ctttactatt actaaaagaa tagcacataa aaaataaaaa
    90961 aagaacacaa atcacatgtg agaagtgtgt tctttttcat tcagctgctt taattacaag
    91021 tttacgccat ttgaggcaat tacttcttta taccaatcaa aagatttttt ctttgatcga
    91081 ttcagtgtcc catttccttc atcgtctaga tccacataga taaagccgta acgtttactc
    91141 atttctcctg ttgatgcact gacaagatcg atacatcccc aaggcgtata gcccatcaaa
    91201 tctacaccgt ctgctactgc attagccatc gcttcgatat gacgacgtaa ataatcgatc
    91261 cgataatcat caataatcgt gccatcctct tccatatgat caatggctcc aagaccgttt
    91321 tcaacaatga ataatggttt ctggtaacga ttgtataatt cattcaatgc gattctcagc
    91381 ccttctggat cgatctgcca gccccattca cttgcctcaa gaaacggatt ttttactcct
    91441 cccagcaagt tcccttctga agttgctgct tgtggatcag tctcattgat tgccgtagac
    91501 atataataac taaatccgat gtagtccact ggatattctt ttagcaactg gaagtctttt
    91561 tccgtttgct ctaatttttc cggatcgact ccatattttt tatgggtacg cgctgtgtat
    91621 gcagggtatt ctccacgtac ttggacatcc gtgcagaaaa aattgaattc ttggttttgg
    91681 atcattgttg ctgcctgatt gactggattg gcatcgatgc tgtaagttgt tgcatagata
    91741 atcatgcagc cgatttggat atccgaacgc aattcgtggc cgatttttac ggctttgcta
    91801 cttgcaacga attgattatg ccatgcttgg aaaatatttt ggtactctcc tgctccattg
    91861 ctttttacta atccttgact taaagctgga aagtgaaagg ccgaattgat ttcattgaaa
    91921 gtcatccaat atttgacttt actgctgtat ctctctaata ctgtctgagc aaatcgttca
    91981 tagaagtcga tcagttttcg atttttccag ccaccgtatt cttttgccaa atgaagaggc
    92041 atttcgtaat gagaaatcgt gatcacaggt tcaatatcat attttaagca ctcatcaatc
    92101 agctgatcat aaaattctaa tcccgcttcg ttaggagtac cttcgtctcc atttggaaaa
    92161 attcgtgtcc aggcaatcga aaaacgataa catttgaatc ccatttccgc aaacaaggca
    92221 agatcttctt tgaaacgatc gtaatgatcg attcctcgat gattcgggta aatatatttt
    92281 tcttgatcaa tcgtccagtc aaattcttca ctgccgataa tcgcaaagcg ctgcttacct
    92341 ccaggcatag catctgcaac ggatagtcct tttccgtctc gatcataagc cccttctaat
    92401 tgatttggca gcagttgctc caccccataa aaatttttct gaaaaacgtg attgcatcct
    92461 gatttcctcc ttattttaca attgccagaa catcttcgtt tgcaataatc tctttttggt
    92521 ctaattcaag tatatcggca aatgcatcag tattcgtaat gacaactgga gtgattacgc
    92581 tatagccagc tgctctaatt gcttcgatgt caaaacgaat caataaatct cctgctttga
    92641 cgagatcccc ttgtttgact aagatctcaa agccattccc atttaattct actgtatcca
    92701 tcccgatatg aatcaaaatc tccgctccgt cagtcgttgt gatccctaca gcatgtccag
    92761 ttggaaaaat agtcgtgatc tctccgtctg caggtgcaac tagttctcct acttctggat
    92821 caatagcgat accttttccc atcacgccag aagaaaaaac ttggtctggt acttcactca
    92881 atggcagtac tttacccgtt aaaggacttt ttaaggtatg ccgtgctgaa gtaatcggtt
    92941 ctcctgcatt cgcatgtttg ttttctaatt gattgtcttg tgtttgttcg tcaaatccta
    93001 aaatcaatgt acctacgaat gcaagaacaa aagcaattcc tgtagctatt actgctactg
    93061 tcacatttga ctctacacca tccaccgtat taatgaaagt cggaatcgtc aataagctga
    93121 ccaaactgct ggagaaagct tttactccgg aaaatccgat aatagctcca ccaatacctc
    93181 cagaaataca agcggcaatg aatggtttct tcaaaggtaa tgtcacacca tacacagttg
    93241 gttcagtgat tccaaataac gaagtcactg tagaagaaat ccctaatgct cgaagtttcg
    93301 tatcttttgt tcgcaatgct acagctaaag cagccccacc ttgtgccaag atggctggaa
    93361 gaagcattgg catcaataca tcaaacccat attgttcgat attcaaaaac atgatcggta
    93421 cgaatcccca atgcatgccg aacatcacga atacttgcca taaacttccc atgattagac
    93481 ctgctacgat tggactaaat ccataaatcg agttgaagag accgcctaaa gcattaccgg
    93541 caaccgtccc gattggtcct aaagcaagaa atgttaatgg aaccatcact actaaaacga
    93601 caagcggaac taaaatcatt tgcagaaatt gcggaatcac tttttttacg aatggctcta
    93661 atttactttg aacccatacg gctagaatga ttggtatgac agaagaagta taaccagatg
    93721 gtgaaagaat cactgggatc ccaaagaaac tgatagcttc tcccgcacca gcaactgctg
    93781 tgatagctgg atacacaagt gccatagcaa ttgctactgc taaaaactgg ttggctttga
    93841 actttttagc tgctgtaaaa gcaagcatga caggtaagaa ggtaaagaca ccatctgctg
    93901 cagcaaacaa tatttgataa gtaccgctat cagctgtcag ccagcccatc accgttgcca
    93961 atgataagaa tcctttcaat accccggcgg ctgccatcgc ccctagaaaa ggtgtaaata
    94021 tactagagat aatatcgatc agacgattca aaatattttt ggactcttct tttccatcct
    94081 ccgaaactgc aagaccttcc tcatccacga tcgattgata aacatctgct acattactgc
    94141 caatcactac ttgatactga ccgccacttt gtacgacttg gatcacgtcc gggtcttctt
    94201 ttaacttttg cgtatctgct aaagattcat cttttaatct gaatcgcaac cgcgtagcac
    94261 aatgtactaa acttttgaca ttcttttgtc ctcctaccgc ttcccataca cgacgaccaa
    94321 ctgcttgatt atccattgtt ttttccttct ttctttttta tttaaaaaat aaaaacccag
    94381 attgaaaaaa acagtcacaa acattcgtga acctattttt tcaatccagg ttttgcctgc
    94441 catacagtaa caatccttat gattggatgc tttttttctc acttactact ctttgaatat
    94501 gaatcgttaa ataaatctgc tctgcgatcc ccatttcctg tttttgcgtt tgtcgaagat
    94561 actcattgat ccgttcgaca caatgaaacg cttttggata ctttccttga actaatgcgt
    94621 agagaaattc atcttgctcg tcagatcctt cccctttgag ataacgctgg gcaaaaaact
    94681 gcagatgagt aatgatacgc tgataattca aagattcttc atcgaacacg atgccgaaga
    94741 atttactgat gatactcagt atatctctta ccattgtggt agcggtcatc gtcacttgca
    94801 tgtcttcgtt tccttgttgg ctattcacaa aatgaaaggc aataaaaccg gcttcatcct
    94861 cagaaagttc cacacccgtc ttttgtttca cgaacaaaag agcctctttc gctgcttgat
    94921 attctttcgg ataaaatttt tttgtttcaa ataataatgg attaggcagt tggatatttt
    94981 cttttgctcg tgtgatcgca taatgaagat gatcggtcaa tgtcagataa atattaggcg
    95041 aaaattcaac ttttagttta tcttcagcca gttcgactac ttgtttgacc cattcgatct
    95101 cctctgccgg aatatcagcc atcagctgct ggaattggtt tttagcaaaa gaatctctta
    95161 aacaaattct ttttggaccg cttctggcga aatctcgtcc ccaatctttt tttgaaaagc
    95221 tagtcctttt cccatacaaa cgacttcttc cccgaatcca tttttcgaaa tgacgacatt
    95281 gttattcaaa attttatcaa ttttcatttt gcttcgccct ctcaagaaaa ataaaaaaac
    95341 ctagaattcg cctactgttt cttagctgaa ttctggtttt gcctgccgta cagtaacaat
    95401 ccatttctta ttcaaaatca tcataccatc gaatttttat ttatgcaagc cttttcatat
    95461 aaaaaataaa aaaactggaa cacaagtcta tctagaaaac aaccaaatca gagatgcacc
    95521 tctttgcgtt tctctttttt tcagcaaatt ggtttttcct tatcgattca tatcctttgg
    95581 ctgtttttaa tctgtaacga cttatgtccc agtatcctaa aatgtttttg tctctagatt
    95641 gaaagcagat ctcatatcat ctgtcgcatc ttttatcgat gtaacacttt ccagttctcc
    95701 ttgtacaact agtcgcgtga cggcgtccat gtcgccacaa gtaattagtg tgacaatttc
    95761 ttttccctcg acttcattca gtaattgggt atctgtagga gcaacttttt ctttaaaaaa
    95821 tgttttgtat gtatacacat tttctaaatc tgtcaaatag atcttggcac ccatctctaa
    95881 attttctagc ggtgtaaaca gcaattcagg gttcgttgca cgatggcttg ctaaggcata
    95941 atttcctttt cccatttctt gatctggaga taatgttcct gctccgtaaa gtagtgacgt
    96001 attatccaag cctttgaaaa ccggtaaatt gattgaaact gaagggactg cgatactagc
    96061 aatcactggt agatctgttc ctctcatttg cgacctcatg accccttctg tcgtcattgg
    96121 ttctaccgca tcaaagtcaa aactgacatc tttatcgtta ttctttttca gatcttcttt
    96181 tgttacattc gctatagcat atttatctcc tgtctctctg acaaaataat ccttgatctg
    96241 ttcattgaaa atcaaagcta gtcctactaa taacaagagg aacaagagga tattgactag
    96301 ccatcttttt gcttttcctt tttttttcat tttctctccc tccagactca ttttactgtt
    96361 tttcttttgc tctttccaac agccgaatga cacatttcta caactctgtg tatttttttc
    96421 gtacacctgc gcttttttct acaggatatt tcaaattatt tttgatcaat ttttcttcaa
    96481 tgatctcatc tagatccagg tgaaggttgt ctgccatcat gtatgaatag atcaatacat
    96541 ctgccagttc ttctttgatt cgttctaatt gtgtttcttt tacttcttcc ggcgttttcc
    96601 attgaaaaag ttctaacaat tcagatgctt ccaaagaaat agagatagcc aaatcttttt
    96661 cgttatgaaa ttgtcgccaa ttacgttcat ctctaaactg gttgactttt tccatactat
    96721 tcatttgctt gccttcttcc aatcacttct tacttgatta atcataccat ttttttacat
    96781 aaaaaataga tgatgctttt aaaaaaactc ctgttttctt ttatttaaaa taaatgtcat
    96841 agaaaatcaa taatttaggt agccaccatg tgtatgcagt agcgtgtctt cttcccttga
    96901 ggctttttgt ttttcgatac gttcttcttc ccaaacagac aacgctacta gaatctctct
    96961 taatgatttt ccttcttcgg tgagcgagta ctctacttta ggcgggactt ggttataggc
    97021 ttttcgatgg atactttcat cttgttctaa ctctcttaac tgctgggtca gcattttttt
    97081 tgtgatcgta gggatttgct tgcttctcca cgcctaaaat aagcgatatt gctcttccct
    97141 ttatctggtg taagcaaagc agttagcatt ttgacgatcg tgggttccgc ttttcacttc
    97201 ttatctactt agtatcatga agtatacttt cgtactaata ctaagtagcg gaagtgtcaa
    97261 ctactttgtt taactacata gcaaaagaaa cagaagggtg acaacggtca tcacgcttct
    97321 gtttcttttg aatatgctgt gttgttgtct ctatctccgt gtagactttc ctcaaactta
    97381 tcctttgaca gtaagtcagt aggctgattt gctctttcta gatgccagat acatttctac
    97441 aaaaaaatag tgattctgtt ttgaaaattc gatttttagt tctgcatttt cgtaaacatc
    97501 caacattttt ttcgcactgt atagacctaa cccgccattt tttttagagg tttttcctct
    97561 tttgaccatc tccgatagcg tcaaattcgt tggatttgcc ttgttcgcta tactaaaacg
    97621 tgatccctct ttttcttcca gcagattgat cgtaatcgga ctctgatcgg ctacacgatg
    97681 atcgaatgcg ttagaaataa aaatagataa acagcgaata aaaacaacca gatcaatcgg
    97741 gattgttttc acttcgacag gaataactac ttggatcggg attttctccg attctgcttt
    97801 ttctagaaat tttaaaaaga cacccctgac agctggggat acaatatttg ttagctgttg
    97861 tatttgcggt ttttcaaaaa tagctgcaga atgatcttct aatatttcta aaaattccaa
    97921 cgtttctttt ttattttcct gaagagtaat ttttaatgaa aacagtagac ttttataatc
    97981 atgtttgaat tcctctagat gatggtaata ttcttcattt atttgataca gttgaagcga
    98041 ttcctgatgt tgtctttctt ttacttggaa actgatcaac ataatggaaa aaaacaaaga
    98101 aaaaaaactg atgactatcg acaaaagaga tagaagcaga taattagatg agcggaagtg
    98161 aacacttccc aataccaagt aaatcacgcc ccagcttaat aaaatacaaa tacctccaaa
    98221 atagtgttca gttggataag taaaaagcaa gttgagaaat ctcgtctgtt tgtctatact
    98281 ttttactaat agatagaaaa taaatgcgat aagtagtgca aaaaaacttg ctgttccaag
    98341 atgtctcttt cctaaataat ccatcagatc aaaaaccaga aaaaagctga gtccagtgat
    98401 agcaaaaaaa agattactga tcaaacagct gataaacagg tttttcgtag taaaataaaa
    98461 aagaaacatc aataataagc caactaggta aggaaagctc actttaggga taggaagtaa
    98521 aagtgtcacc accatcaaag ctatacaacc aaagctgttt tttactagca gttgtttcga
    98581 aaagaataaa tagataccta aatctaaaat caaagtaaag gtcaaataaa gtgtcactgt
    98641 tgcgaccatc ttattcctcc attgttttgt ttcaaaatgt acacatattt ttttaatagg
    98701 agcctgcata tgaaaaagta ttttatcata gaagataacc agtttcacag cgaatggatc
    98761 atcagagaat tggtcaatca tcatatcgag aatatcgtgc agctcacttc tatctctcaa
    98821 atcaatcagt tgatccagtt gggcactatt gataatcacg atgttttctt tatcgatatc
    98881 gacttgaagc aatcactcac aggtattgat gtcgccgaac aaatacgtaa aaaaaatgca
    98941 catagtaata ttgttttttt caccgcttat acgaattttg cagtagagat catcaatcgg
    99001 aaaatccttc cgattggata tatcagaaaa gacaggaatt tatctgaaca aattcgtcaa
    99061 gtgctagaac agatcaattg gaaagaacag cagatcgtaa atgtcgataa aatctttatt
    99121 gatcaaaaag gtggaagtct cgtcctgtat cctcgggaaa ttttatatat tgaaagtatc
    99181 aaaggtttga aaaaccaagt tatggtcaaa acaactacag aagataaatt agtgaatact
    99241 tctttaaaac aattgaagac agagttagaa aagtatgctt actttttact tttaaaatct
    99301 tactgtatca acttatcgca attgcagaaa attgattctg ctcattatgt gttagaattt
    99361 ttcaacggtg actccttact cgttggtcga aagatctttg aaaagacaaa ggaacgtttc
    99421 catgacttcc aaaaaactgc ttcgagttga tgaataagag ctgagacgta agcatagcag
    99481 atttcaggga gtgggccttg aatcggctcc actccctgaa atcgttgata tgattttacg
    99541 cttcctcttc tgtaggagca tctgttaacg accatgtgaa tgttgaaacg tagttgtcta
    99601 cagcataatt ggatacagga acaaataatt ccactgattg tctcccttgt tccacattct
    99661 ctcctaatga ataaatccat gtgccaatcc cttcatttgc tcctgcagtt actagatcta
    99721 ctgcctgatc tgctgggatt tcgattcctt cagcgccagt tccagaaacg gtagatggca
    99781 ttccactgct attagttgcg ctatttcgaa tcacggcgtt tttgaatttc acctttgaac
    99841 cagttagttt attcgtatca gatgttgtac caataaattc tgttcgtttg actgataatt
    99901 tccaaccggc ataatttccg cttttatccg ttacttgtac gaaattctgt acttgtgttt
    99961 gtgctccagt actgtccgtt ccgctttgta atgcagcata tactgttttt gctgtaccta
   100021 acttgattgt tccaaaatca agatctggag cttggtcaat cgtcagtaat ccggatgttc
   100081 cctgatttgg ttcgtcaggt gtaaaaggag tatcaggatc atttggatca acaggaggaa
   100141 ctggaacaac gtcttcagga tttgcagcat ctggtttggt cacagaaatc gttccttctg
   100201 tagtggctga gctcttattc tcagcaaaaa cactttgtgt acataataat agacttccag
   100261 ctagaacggt acttaatgca attgtttttt tcatttcttt ttccttcttt cttttaaaat
   100321 aaataatcca gcaaataagc caataagaat gactccaaca agtatcagcc atcgccagtc
   100381 aaatgtttct ggctgatttt ttaaatcaat atccttttca ttcaattggt ccgctgcatc
   100441 atcagttatt tcaaaatcgg tatggagatt ccagcgtttt tctttccaag cacccttcac
   100501 aaccgcttga taatgtcccg gagctaattt ttttccttct aatgggacaa gtaaatcaaa
   100561 atttgtattg ggtgctacat ctattttttc tttttttatt gaaaggtaag gctcttttgt
   100621 ttcttttttg tagatttcaa ccgatgtagt caagccgaac atataagaag catttggatt
   100681 ttgaagattc gccttaatca catttcttcc atcgctttga tccgcataag ctttttttaa
   100741 tttcaaatct ggggaagact ctttttcgct atttcaaatc aagattgctt tcacttgaga
   100801 aaactgattg acgacaccaa ctgtactttt gttagaaacg ttctcttttt tttcttgaaa
   100861 cgtgatccct cctgcgacca caccagccag ctctttttct ggcgctttca gtgaaagtgt
   100921 ctcagtgacc gcactttgag gaggaacagt tatttctccc actgtttttg ctaagttttt
   100981 catatcataa cttaatgttt catcaaattt actttttgat tctccatatt cgatcacacc
   101041 gtttgaattc gtcgtagcgg agtggatcaa tgtctcaact gttactgatt tatctgttcg
   101101 gttaaagacc gtgtagggga tttcctgtgt tttcccaggc tccatcctta catttatata
   101161 tgttttgttc ttatcaatct gattagccgg taattcaaaa tctaccgcaa aattgaattc
   101221 ggaggcatgg acaggtgtct gccaaaggat gaatccaagg agaaggatca taagtaaaga
   101281 gcagttgttt cgatgacttt tattccatat tcgattcatc aatcatcctc cttgatcttt
   101341 attctgtcgg cgcatctgct aatgtccatg ttatctctgc tgagtaatta ccagctatct
   101401 gattttcttt ggttaagaca agtttaaacg cccgaccgtt atttaaatat tctgaataat
   101461 ctgcttgcac attcgttgaa ttttgtcctc tgacaatttc cagttcttct tcattcacta
   101521 attgatactc ctctcctttc ttgaaatata ggacatcctg catagaaaat cctgcatcat
   101581 ttgtgaaagg ctgagataat tttatcgtta agatccacgg atttttcgtt tctcgctgat
   101641 cataaatcca taatttttcc tgtatatcca tttggccaaa tgcttcttgt gtcaaaccag
   101701 ttgctttgat ctgaccaaaa tcgagtttgg aaggggcaag aaatgagaga ccaccttcta
   101761 ctacgatctt cgtagcaggt gcaaaaggcg gggcatcatg ataaacaact ggcgtatcac
   101821 ttggattgtg attcccaatt tcatcgttgg tacttggctt gttctgcaca cccttagcag
   101881 tagcttctcc tgcttggtcg tttaatacaa tttctaatac atctcctgca aaaagttgat
   101941 tttctgggat agaaagaaca aattcccctg tatcatcaat agttgtttct gacaaaacag
   102001 cttgattttt tttcaatgaa accaaggctc ctgcttcacc tgtacctgtg atcgtgcgag
   102061 aagctgcatt gatcaatgtg gtacttaaat tagcaggttc aggaggaatc acatcgactg
   102121 tcgttttggc agagtccagt tctgtcactt cttggccacc tcttactttt ttagcagcaa
   102181 caacttgcac ttgatcctcc gtttttaatc tctcatcatt gggtacttga acttcgaaca
   102241 agccgccttg ttcgccttct ccccatgggt tatatcctgc cccttcattt tcatctgttt
   102301 gtccttgcgt gagagcagta atttctacag atgatttcgt cgtatctgcg taagtaatac
   102361 gtaaagtcac ttctacttcg cctgtccaag catctcttgg ctttgcctcg acaccttcgg
   102421 gaacaacgac atgcccatag atttttttat ctgcattcgt tggcactctt aaggattcaa
   102481 tcatcgggag ctgattattg gcactgattc gattataatt tttcattccg gcacctgtct
   102541 gagcaaattc atttgttaaa cctgcactag ggcttgatac gaaattgcct aagtcggtcc
   102601 cattgatcga taagtctgtc atatcagaaa aataatccgg gtctttttca aagttatcga
   102661 atgttgcgcc tgtttttcgc cataaagcga tttctgaatg ggcgatcttt aaagaagaat
   102721 ctccatttcc ttggaatacc cagccgccta tgccattggt ctcgcttcca atccgtttgt
   102781 tttggaaatc aaaataggta ggagattcta agtccacatt caacacatcc ccactgatga
   102841 tgccggtctt atcttcccct gttttcccga ccatgactaa ataagttttt tcacctgccg
   102901 taaaatttaa atcaatatct ccagttgtat ctacagttgc tccggaatct gcgcgtatat
   102961 cgatatttga tttttctcca gtgactgtaa aatcagctga acctggactt tctagaaaac
   103021 cagaagcgtc ataaaattgg atcgcttgat ttccttgatt gagtctgttc acgtaagatt
   103081 tgccatcacc tgtatttctt accctcaatg agcctccatt ggttactgtc agcttttgcg
   103141 taccattctc aaaacgaact gcgctggaac gcccactctg cttatcgatg tcgataactg
   103201 atccggctcc ttctacgatc aaagaaaggc cttttcctac aaaacgcatc ccattgttcc
   103261 cgggttgatc gtcatctcca gccattttga ccgagatttg tccaccactt gatacatgga
   103321 tttgactaga atctccttgc aagcgaaatc cgcccgtagt tgctgtattg atggtgattt
   103381 tcccaccatt cgatacagtg actttcgatc ctgaacctct catttggatg attccgcgat
   103441 tgttgtcatt ggtaatattg atctttgtat ttaccgaaaa ttcgcttccc gaaccactga
   103501 cttcaaacat gacattacca ggtagcgtat cgactgcctc tccttcatcg ctaacgccat
   103561 ctgcccgatc ataatcaaga gagacctttg aaccgcttaa gatatggatt cctggcgctg
   103621 tttttccact accagtctca tctcctgaat ctagaaaacc gtagaatttc cctagatacg
   103681 gtccataaag ttgactacca ttgatcacat tcaattgata gcttctacaa aaataggctt
   103741 tacccggagc ggcattcagt ccttccttca ctggttggac atccaacaca ccggaaacac
   103801 catctaatgt gacagttgca cgaggagcgt aaatcagtcc taatttggac ccatcataca
   103861 aatcaagtgt cccggtaaat tttatttctc ccgtaaaatg atatctgctt ccccaaaaat
   103921 cggtcatata agcaatgata atggcatttc catcgatatt tggtgtcaat ccacctggat
   103981 gtgcagctgt tcctttaaaa ttctggaact cgatcgactg aggtatctca ttgatataaa
   104041 tatggtgtgt gccgaaattg tgagcgaatc caccaaaatc aataacgata tctcgtttga
   104101 tctctaattc cctgtctaaa gtcaaaggct gaatcagtcg gatcttagtt actgattcgt
   104161 ctgcgagaag ctgcgccagt tcttctgttg tggcagcttc gctgtaccca tccgctgaaa
   104221 cagctcttgc cagtgccgct tcactgctat cagacgtttg ttcagctact tctgaggtct
   104281 cacttgtctt attttcttct tgccttttat tagtagaagc ctcactttga gattctgtag
   104341 tttcagaagt aatcgattct tctgaaaaag tagtcttgtc aaaactttga ttctctgatt
   104401 gcgttgattc gtttgttttc tctacatcgg caaaaacgga tgtcaccatc aagagaggga
   104461 agacaaacaa aatcgacgca atcagctttt ttacacattg attcattctc caccatcctc
   104521 tctgacgttt tgacaatttt attttatcgt tttaatctat ttccaattgt actttcatat
   104581 ttaaaatatg tatttttatg gaaaaatttt tctattaggt gtaaatttct tttttgtaca
   104641 aaaaaaaggc tgtgacaaaa gtcttgtcac agtcccttat cccgaacaag cggtgttctc
   104701 ccgccaactc ctcggtcaca acctccattt taacaataaa cctgtaaatg tgagggcaat
   104761 actttgattg tcacaggtaa tttatcccct tcatctccat caacattcgt cgtcaattct
   104821 tcctcatcag ctaatgacac aactaattgc tcacaagtaa ggtaggctag atttttcgta
   104881 gattcatcta ctccttttaa taggtctggc aatgttttaa gcgtatcgat caaagaagaa
   104941 tcttttaaat aaaccaaatg gagcttacca tcatccactt ttgcatttgg aagtaatgtt
   105001 tcaaaaccgc cgactgagtt agttagtcct atcagcaagg tactgctctc aatttcttcc
   105061 ttctttccat caacttctac gtgaaacgag taggattgtg tggaagctaa ctgtttgatt
   105121 cctgacatga aataagctag ttttccaaat ttcgtcttct tctccgcatc tacatcattg
   105181 attgattcag ggatagagcc aattgcgacg acattcataa aatagtcgtc atttattttt
   105241 ccaatatcca atggcttgac tgattcaatc gaaaaatgat tgatcgcttc ctcaggttct
   105301 agcggtatcc ctaatgctcg agccaagtca ttcaccgtac ccaatgggaa aaatccgaaa
   105361 tttggccgat gttcttgttc agcgattcca ctgattcctt cgttgactgt tccatctccg
   105421 cccatgacaa acacactatg atacccttcc gtagccgctt cgcgagtaaa gttttttgca
   105481 tcccctgctt tttttgtatg caagacgacc acttcatcaa acaccgattc caattttgct
   105541 atcgctaatt gctcaaattc ctttgcttgt tcaccgcctg aactggggtt taccactaat
   105601 aaaacttttt tcatcacttt ctttcccttc tgattgattt ctttaatata acgatagcat
   105661 aaagaaaaaa attaggctgt gatgaagtac tgttcatgaa acattcattt attttttgac
   105721 aagataaaac atccatacta tgaaactgag gaaaattaaa acaatgatat aggaaataaa
   105781 agaaaatgat aggcattgta tacctaataa agtaaaaatc ttaggtggca gataaaaaca
   105841 caaaaatagc aagagaatgt aatagcgttt cttccacttt ttgttatcag accttatagc
   105901 gatcagagga ataccaaatg cataactgaa aaactcttga tgtactgtta atatgtcacg
   105961 gccttgaata ataaatgcga caatccccgc tataattagt gtgcctaaca ccaaaacgga
   106021 aaattgatga atatatttta tatacaaatg atccattgta cttcctgcct ttttatttgt
   106081 gagaaaaaca aatccgtata cgtgaataac ttctagaaat aaaagaaatt tgcaaaacca
   106141 ctccatttat ctacttctac gtgcattttt tgatattgtt ttctttattt aagattatac
   106201 agaaaaatat ctagggtcgc tggattctaa gtaaaaaaaa tttttaaaat aaaaagaact
   106261 aaatcaagta gtaattaaac tactgttgat ttagttctaa taaaaagatt tagatgaaca
   106321 gttttattga tttaaatagt tcatattttt tatttatacc gcttatttac tacttgctgt
   106381 actagaatct gaagtgaatg tactcaaaac attttcaaag tctttgtctt tgatttttac
   106441 attagcgtct ttcaatactt cgccaattac tttattctgg aaggtactgt cacttaattt
   106501 tgtgtctgtt gcaatttctt tcaattcttt tttgtattta tccatgtcgt tgcctttgtt
   106561 ttggtttttc accattttaa ccacataata ttccgtagta taagttgaag cattggtaga
   106621 agtgatcaca tcagaaactt gaccatcttt caacttaaag gctgcttctt tgacttctgc
   106681 cggaaccgtt gtagtagtgg aatcaaattt cacttttccg ccatcttctt ttgtcgtagt
   106741 atcagttgac ttgtctttgg ctaatttaga gaaatcgtct cccttatcag cagctttctt
   106801 cacatctttt gcatcatctt cacttgctac ttggataatt tgagcttcca cttctggatg
   106861 gaaagattcc caagccgttt ttaaatcttc atcggtcaat ttgatatgtt tctttagacc
   106921 ttcttgaaag gctagacttt gtttgatact gtctttgaat gtttgttctg tgtaacctgc
   106981 agatttcaat tgtgaatcaa atgaatcacc caattgtttc tttgtttgat catattgaga
   107041 atcgatttct ttggttgata cgtcatctcc atatttatct tcaaatactt gataaacgat
   107101 caactgttgc acagcggaat ctgctccttg catttttttc aagctatcca ttacttcttg
   107161 ttcgctgatt gtaccgcctt tataactaac ggctgttttt tcaccggcat tcgtacagcc
   107221 tgacaataag ccagtgccta gtacgatggc aagtgctaaa aatctttttt tcatttatca
   107281 attctcctac ttttcgtttt ttgcgaattg ctaaaaacaa aggtgttcaa gatgaaaatc
   107341 atcaagaaca cctttactaa tctgctcgat acgtcctgaa tagatataag gctacacaat
   107401 ccagaaagtt cgctcagcag aataaatgtc aagtagcaca tcacacctta atatactact
   107461 tcttttgtta ccgtttttca agtctatctt gcgttccgta tttaacgtaa ctaattctta
   107521 gaacaaatgt tatcgatttt gtttttcttc ttccgctgct gggatattca aatcagacac
   107581 ttttatgttc gattttccag acattttttt gttgttttta ttatgatata tttttataca
   107641 actaaaaatg aatatattaa aactaccaaa aataactttt aacgctgttt cattatatgt
   107701 tttttctatt ttatataaac ttttggatac ttaataccaa ccggttggat tgtaccaaca
   107761 tgagaatgtg tcagttctat ttcctgtcgc acttgcatag gcccatactc cttttgttgc
   107821 atttgctgat cgaatagagt ttccaacttt cgcttttgca ccgtgacgat tatagacacg
   107881 actatagtgg ttagaatgac ctgtttttct cgtacaagtt gtatcactat aataaaccca
   107941 tcttccagag ctatgattaa ttgctgttct agaaatttcc cggtctactg gtaaatttga
   108001 cttaataata ttacctttag catcaaaatg aatctctcct ggctttaaag atttgtaata
   108061 gatttcaccg tgaactgaat ttgcttccac ttcagatgac atagcgtttc ctccaacaaa
   108121 acctatccct agtgcacaaa taataactgc ttttttcata aaacgacatc ctttcctttt
   108181 tgatttttaa agcatgatct tcttgtttcc tattttggtc agatatggat catgcgtgac
   108241 tacgataact aacgtacctt gggaagcttg ttgcgataag atttcaacta ctttatcctt
   108301 atttctttta tccaatgacc cagtcggttc atcggctaaa atgattttgc tattcttcaa
   108361 taagactctc gcacaggcga ttctttgctt ctcaccacca gataatgtgt agataggcgt
   108421 acttagcttc ttgtttatat ttactttttt caatgcctca tactttgctg ttcgcttatc
   108481 tgaaacattt aaattcgaaa acttcaatcc aatatctaaa ttaaaatcga ttgtttcata
   108541 ttcaatcaac ccaaaatctt gaaaaagaaa agatatggta tttcttttta tcaagcgctt
   108601 ctctctccca gttaattgtt tcgtctcttg atcgaacaaa tagaattgtc ctgaactgaa
   108661 ctgatcattc aatcctaata tattcaataa cgtactttta cctgctccac tttctccaac
   108721 aacagtcaca agatccccag catccgcagt gaaacgatcc aaatgaagaa tcgttttgtt
   108781 tcgaatgatt tttttcgcac cttttatcac tatcaacggc tccaattgtt aacctccatt
   108841 catcagcaat aactgacttt tcttttctgt agacaaaata aaaacaactg aaagaataaa
   108901 atcaatgaag ctaaagaaaa aaatattaaa aagatattta ggctctcttt ctataagaaa
   108961 aaggaagatt acacttgtcg ttccccattt gatgaggttc atcatgaaga aatctttata
   109021 cgtttcaaag agcgaataac cacttgaacg aaagatagcg attttccgac aattgtagac
   109081 aaaatatatg cataacatga catagctcaa caagaagaaa gaaaagaaag tgagtaaaaa
   109141 tatctgtatc aagtaatgaa atgatctgct taacactttg acagctatct cttcagtctg
   109201 agtatacgga aatgataact gcaagttatc acgtaactga ctttcttcaa tcagctcaaa
   109261 taacctttct ttcgacaaag agcctatctt gatctttaac ggtggataga tttctccgct
   109321 gagaatattt ctttccaaat acatactgtt tttcaatgtc agtatttcaa caaccggata
   109381 atgttcgatc caggggatag aaggaataaa tgtataaatg ggttgattgt tttttataaa
   109441 tagaaatttc ggttcttttt cactgatttc ttgataatat tctgttattt gcgccaggtc
   109501 attttttaaa tctgtatgtc tatatcgttc agggatcaat ataacagggt gcgtttcttt
   109561 ttcggttatt tggatcaacc ttccagagac atcaatcaaa ggaaatttct taagataatt
   109621 cagatttatt tttatccctc tgccaaactg ttcattttct tcattcaagt aatctgatac
   109681 attgactaat atacttccgt ttttattcaa agtttcatat aattcctgat ctgctgctga
   109741 tgcaaaacga ttggaataaa taaaatccac gtggtttttc ccgatggtta ctggataaaa
   109801 tacatgatag tcctcaccag cgatttcttt tggtggttca tgggaaacag ctaactgtga
   109861 agaagaaaaa acgatagttg ctaattcgac attggcaacg gtcaaaagaa gagaaaacaa
   109921 caatccaaat gtaaaaagaa tgtattggat atagttgaac gcttctctta acgaagcgat
   109981 tttttcaact aataaaagag aaatcaaaga gataccatat attccgctga acaagaaaac
   110041 gtacatctgg aacaaataaa gaaattgctc cttataatac ataaaaataa aaccaccaat
   110101 gattcctgca attatgaatg taataatgat tttctttttc cccaataaac accacaatac
   110161 ttgatgtaat gaaaagtcat tattcaacaa taaactgatt tctttattca tcaataagaa
   110221 aaaggatgat aacaaaagga ataaaagaat caatccaata gttaaataca ctcgataatt
   110281 atatacgtct gtatttgaaa taaccgaata cgaatagcta ttttcaaagt cttcaaaaat
   110341 attagtggca taatcagtgt gaaatgcttg attgaatcga tcagtgaata gtgaaatgaa
   110401 ccgttcatag gcttcttttt ctctcgtcat caagaaaaat tcaccttcaa aatcttttat
   110461 tttgatcgat tcttcaatgg acgttacgcg aaaggaggta ttagaatagg gtaccttctc
   110521 gtgagaagat ttgacatccc cttgataata caatgtcatt tcaagctttg gctgtatctt
   110581 gaagttccaa gatgtatcta cttcattgga ttcatttact gtttttttca tataagaaag
   110641 ctcagtttct gatgagacat tttcaaatac catgattagc tgctcatatt cttcttgccc
   110701 aataaaatgt tgtggcaatc gaatcggagt ataagtatct gtttgatgga aaaattcatt
   110761 tgtccgatag agtacctgtt tatttatact aaccaaggca aaaccactca tgataccggt
   110821 cactatgatt gtgagtaaaa ctgtgaactt ttttttgatt atcaccactc tcccttactt
   110881 aaatgattct ttgataaaat cataccgttt ttcatcaaaa aaacgtatct atcaagtgta
   110941 taggtcatgt agaataaatc tatatactgt agaatcgaaa ggagaagaag atgaacaccg
   111001 gagaaaaaat acgaacttac cgcagaaatt gtaagcttac gcaaaaagaa ttaggcgaaa
   111061 aaattggtgt ttccgataaa acgatttcta gttgggaaaa ttctcgtaca atgccagacc
   111121 ttgaaatgct gtcactttta catcatactt taggtctgcc gattgatttt ccttctattg
   111181 aatcagctac cgaatcaata gaaccaacat tgccagatga acctcttgtt aacaagaaat
   111241 cttattcatc aaaacaaccc ttctcactca aaaagacact atctttcttt ctgctcgtct
   111301 tttgtttggt ctatcttttt cttatcaatt atcaatacaa aaatgaaacg atcgatcgat
   111361 tcaatccttt tttgaaacca caaatcggct ataccacact ccctgtagga tacgtggaca
   111421 attccatcga acgttgggta tgtaatgata tctttggcca tggtacatgg ctgtcttttc
   111481 acgctggaga ggtagaaaaa gagaaaaacc atgctgtaat caaacacaaa ggaaaacacg
   111541 tcatgaacgt tcgcctgctc acttgggaag ccattccctc agattaccaa gaaatcctca
   111601 gccaagacta tgacgacgcc ttaaaaagaa gccctcagga gccagatagg cattaagtag
   111661 gagatgaacg tagagataga aaaaatcaat gcacatgatc ttatccaaaa aacaggggta
   111721 caaattaatt gaaaaagcct tgagatgaaa gttcctaaat aaaaaagttc agaatgatag
   111781 gtatttctgg cttatagtat aatatttacg ccacagcctc ccaatgattc tttttggaat
   111841 cataatcaag gatggacatt cacaaaaata ttttgctcat tcgatccgaa tagattaacg
   111901 accaatctag taagtaatat agattggtac gtagtcaagc tgcacataat ttagatcaat
   111961 tttagttctt ttttatattt ctatgatctg ctcatttact tttatatgat ggcttacagt
   112021 aacataaata aatatgataa tcgctggtag tttatccaag agtactcaat aaaatacaaa
   112081 atggattgtt caagcgccta tcataatgat aaaatgaaac aaataaacga tacaaggagg
   112141 aagagacttt gagtaatggc agaacaattt tttcattgta aaaattgttc agttgttaat
   112201 ctatgggatt tcggtagcat gggcattttt ttatagagga atcacaccaa cctggccgtt
   112261 ttatctcttg ttagtgggaa tattagtagg aaattttgcc cctcttcact atcgtacgaa
   112321 cttttttcca actgattctg gcctttttct taaaacaaag acgcgaaaat tagaaaacat
   112381 tattgaaatg acaattacct gtataatcat tttcttagtt atattcctaa acgtcttcta
   112441 ataagaatct cttaaaatta gcttgttaca gttagttacc tagtttatat aacacagtta
   112501 tcttatcttc cttatcaaca tcttttgcca actctttgtc ttaaattcga aacatataag
   112561 cagagctacg aacaccaaga ctgtttcggc tctgtttttt gcatcaaatt cactcttata
   112621 tagctgataa tctcggctct ttaaaagaaa ttattttcgc ttcattttat tataaaaagg
   112681 ctaggaacct tgatgttatc aggttcctag cctttattta agtattaccc cacagaccct
   112741 tccatataga tttttaaatt acacactagt ttaaactaaa acaaacaagg aaacacttac
   112801 catttaatca taaaattagc tcatatgaat atattagaat gtaaaataga ctggtcaaaa
   112861 tctggtcaaa aaagaggact aatacaggta gtcctcagac tgtagacaaa gtccatttta
   112921 tggatgat
//
LOCUS       DBBGSZ010000005       109391 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.005, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000005 DBBGSZ010000000
VERSION     DBBGSZ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 109391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 109391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..109391
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.005"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(28..1419)
                     /gene="sufB"
                     /locus_tag="ACIZE5_000486"
     CDS             complement(28..1419)
                     /gene="sufB"
                     /locus_tag="ACIZE5_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HGC6107659.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKCEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(1424..1894)
                     /gene="sufU"
                     /locus_tag="ACIZE5_000487"
     CDS             complement(1424..1894)
                     /gene="sufU"
                     /locus_tag="ACIZE5_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HGC6107660.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(1881..3116)
                     /locus_tag="ACIZE5_000488"
     CDS             complement(1881..3116)
                     /locus_tag="ACIZE5_000488"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HGC6107661.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(3113..4399)
                     /gene="sufD"
                     /locus_tag="ACIZE5_000489"
     CDS             complement(3113..4399)
                     /gene="sufD"
                     /locus_tag="ACIZE5_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HGC6107662.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(4412..5185)
                     /gene="sufC"
                     /locus_tag="ACIZE5_000490"
     CDS             complement(4412..5185)
                     /gene="sufC"
                     /locus_tag="ACIZE5_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HGC6107663.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(5382..6230)
                     /locus_tag="ACIZE5_000491"
     CDS             complement(5382..6230)
                     /locus_tag="ACIZE5_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGC6107664.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(6254..6940)
                     /locus_tag="ACIZE5_000492"
     CDS             complement(6254..6940)
                     /locus_tag="ACIZE5_000492"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HGC6107665.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(6933..7967)
                     /locus_tag="ACIZE5_000493"
     CDS             complement(6933..7967)
                     /locus_tag="ACIZE5_000493"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HGC6107666.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(8030..8286)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8362..8700)
                     /locus_tag="ACIZE5_000494"
     CDS             complement(8362..8700)
                     /locus_tag="ACIZE5_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HGC6107667.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(8702..9058)
                     /locus_tag="ACIZE5_000495"
     CDS             complement(8702..9058)
                     /locus_tag="ACIZE5_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGC6107668.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(9064..10251)
                     /locus_tag="ACIZE5_000496"
     CDS             complement(9064..10251)
                     /locus_tag="ACIZE5_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGC6107669.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(10442..11287)
                     /locus_tag="ACIZE5_000497"
     CDS             complement(10442..11287)
                     /locus_tag="ACIZE5_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGC6107670.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            11521..12486
                     /locus_tag="ACIZE5_000498"
     CDS             11521..12486
                     /locus_tag="ACIZE5_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HGC6107671.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            12863..13906
                     /locus_tag="ACIZE5_000499"
     CDS             12863..13906
                     /locus_tag="ACIZE5_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HGC6107672.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(13968..14432)
                     /locus_tag="ACIZE5_000500"
     CDS             complement(13968..14432)
                     /locus_tag="ACIZE5_000500"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HGC6107673.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            14678..15625
                     /locus_tag="ACIZE5_000501"
     CDS             14678..15625
                     /locus_tag="ACIZE5_000501"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGC6107674.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(15836..17908)
                     /locus_tag="ACIZE5_000502"
     CDS             complement(15836..17908)
                     /locus_tag="ACIZE5_000502"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_function: GO:0098847 - sequence-specific single
                     stranded DNA binding [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0051304 - chromosome separation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HGC6107675.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(17841..18218)
                     /locus_tag="ACIZE5_000503"
     CDS             complement(17841..18218)
                     /locus_tag="ACIZE5_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HGC6107676.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(18347..18907)
                     /locus_tag="ACIZE5_000504"
     CDS             complement(18347..18907)
                     /locus_tag="ACIZE5_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6107677.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            19057..20349
                     /locus_tag="ACIZE5_000505"
     CDS             19057..20349
                     /locus_tag="ACIZE5_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HGC6107678.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(20409..21527)
                     /locus_tag="ACIZE5_000506"
     CDS             complement(20409..21527)
                     /locus_tag="ACIZE5_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HGC6107679.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(21541..22962)
                     /gene="arcD"
                     /locus_tag="ACIZE5_000507"
     CDS             complement(21541..22962)
                     /gene="arcD"
                     /locus_tag="ACIZE5_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0043858 - arginine:ornithine antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA];
                     GO_process: GO:1903826 - L-arginine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HGC6107680.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLITDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(23208..24329)
                     /gene="mnmA"
                     /locus_tag="ACIZE5_000508"
     CDS             complement(23208..24329)
                     /gene="mnmA"
                     /locus_tag="ACIZE5_000508"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HGC6107681.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            24733..25332
                     /locus_tag="ACIZE5_000509"
     CDS             24733..25332
                     /locus_tag="ACIZE5_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGC6107682.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(25470..26756)
                     /gene="efmA"
                     /locus_tag="ACIZE5_000510"
     CDS             complement(25470..26756)
                     /gene="efmA"
                     /locus_tag="ACIZE5_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HGC6107683.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(27027..27371)
                     /locus_tag="ACIZE5_000511"
     CDS             complement(27027..27371)
                     /locus_tag="ACIZE5_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HGC6107684.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(27508..28653)
                     /locus_tag="ACIZE5_000512"
     CDS             complement(27508..28653)
                     /locus_tag="ACIZE5_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGC6107685.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(28833..29807)
                     /locus_tag="ACIZE5_000513"
     CDS             complement(28833..29807)
                     /locus_tag="ACIZE5_000513"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGC6107686.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(29887..30762)
                     /locus_tag="ACIZE5_000514"
     CDS             complement(29887..30762)
                     /locus_tag="ACIZE5_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HGC6107687.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            30892..32799
                     /locus_tag="ACIZE5_000515"
     CDS             30892..32799
                     /locus_tag="ACIZE5_000515"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M13-type metalloendopeptidase"
                     /protein_id="HGC6107688.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(33340..36618)
                     /locus_tag="ACIZE5_000516"
     CDS             complement(33340..36618)
                     /locus_tag="ACIZE5_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HGC6107689.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(36889..37434)
                     /locus_tag="ACIZE5_000517"
     CDS             complement(36889..37434)
                     /locus_tag="ACIZE5_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGC6107690.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(37446..38138)
                     /locus_tag="ACIZE5_000518"
     CDS             complement(37446..38138)
                     /locus_tag="ACIZE5_000518"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HGC6107691.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(38157..38441)
                     /gene="macP"
                     /locus_tag="ACIZE5_000519"
     CDS             complement(38157..38441)
                     /gene="macP"
                     /locus_tag="ACIZE5_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HGC6107692.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(38454..39017)
                     /locus_tag="ACIZE5_000520"
     CDS             complement(38454..39017)
                     /locus_tag="ACIZE5_000520"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGC6107693.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            39245..39907
                     /locus_tag="ACIZE5_000521"
     CDS             39245..39907
                     /locus_tag="ACIZE5_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HGC6107694.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            40031..41227
                     /locus_tag="ACIZE5_000522"
     CDS             40031..41227
                     /locus_tag="ACIZE5_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HGC6107695.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(41328..42704)
                     /locus_tag="ACIZE5_000523"
     CDS             complement(41328..42704)
                     /locus_tag="ACIZE5_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HGC6107696.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(42741..43607)
                     /locus_tag="ACIZE5_000524"
     CDS             complement(42741..43607)
                     /locus_tag="ACIZE5_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HGC6107697.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(43696..44721)
                     /locus_tag="ACIZE5_000525"
     CDS             complement(43696..44721)
                     /locus_tag="ACIZE5_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGC6107698.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(44739..45413)
                     /locus_tag="ACIZE5_000526"
     CDS             complement(44739..45413)
                     /locus_tag="ACIZE5_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC6107699.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(45597..46490)
                     /locus_tag="ACIZE5_000527"
     CDS             complement(45597..46490)
                     /locus_tag="ACIZE5_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HGC6107700.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(46564..48261)
                     /locus_tag="ACIZE5_000528"
     CDS             complement(46564..48261)
                     /locus_tag="ACIZE5_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HGC6107701.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(48254..49567)
                     /locus_tag="ACIZE5_000529"
     CDS             complement(48254..49567)
                     /locus_tag="ACIZE5_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HGC6107702.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(49567..53508)
                     /locus_tag="ACIZE5_000530"
     CDS             complement(49567..53508)
                     /locus_tag="ACIZE5_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HGC6107703.1"
                     /translation="MEKLDEPIVPSGQALQRIQRQLFNGILERLGPTATQDPYEYIYP
                     SGEVENEQHRYPKFTTNDYTKVLGNWTQSNERYQGDKGSPYDGENLIDDSDYTNGGAN
                     WRNYDYATNNGSTAGEEDRNVPAQTVQLWGNERNFENSYLDYNGAYIKKWVEPVLPSS
                     TASDLHPEDATTLYNVYLDVIGGEKKEISPIDIVFVLDKSASMSELTAGTNSQTKNAA
                     LIEAVNEMSKDLLSDPSLDIRIGMVNFYHNSTAINNHEQISSDIFPLTNDINRLTGSE
                     NTALNRTPIGGTPLTLGLKNGYETLYKDNGGENRNPEKILIVVGDGTPTFSYAPIQSS
                     YRTSTNGAWSNWTVMEDKIAEDNDVLFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDE
                     VNVHYRYGEVKEGDNKATHWVGDGSSNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQE
                     NPPSIFSIGLGIDGNVSGRQRLDAIGRNVLKNIADLEEDGVTPRYYNANNKNDIVTAL
                     EDISSTFKRTIQQATLYDETGFNVSPFGAGRSADIQFYHLDPGENGMKYQEPEIWDEE
                     RHGQAPPEVVATPTTYVGRENQAYKFSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVN
                     NMAYIQNLEDYENDITTGRMYFPSSSIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQ
                     NPESGEAEPIETSKTTTDGIAIFETKMPILGDETGAVSDIFWIREIAGPPRYQLVDET
                     YQFQIKKYAANEDEMLGHYELVDEYTSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNI
                     EGTEYDELYVKLEMRNEFKPIHMNINKLIEGSNMPINGAEFELYETDGNGLEIGYPVA
                     KGLSGVNEVEEEKGRLTFYSVDEDGKYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAE
                     YKIIESQNPEGFKEPDENDTWILRLYDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWV
                     AFTAYNTFDYREIRVRKLDHEGHTLDGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKR
                     LPGIGYFYSRAVGVEKYVDLNYDQPLHLSIGEYEVSESVAPNGYRLSDQVFQFALNEE
                     GKFIIEDTVIEDETAPLPEGYEIIDGVLQVTLEDELAPIDLELLKIDSMNSRRLEGAE
                     FSIEKQNSAGEYEIIEGGLAPDPNDSSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFI
                     LEISYREEPDIENDRVVPGKEAGTLKVEISYYPNEEAETPDLQQELEYELLETNRIRL
                     QLSVGNDPENPLPATGGSGRLFYILLAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(53617..54075)
                     /locus_tag="ACIZE5_000531"
     CDS             complement(53617..54075)
                     /locus_tag="ACIZE5_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGC6107704.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(54373..54891)
                     /locus_tag="ACIZE5_000532"
     CDS             complement(54373..54891)
                     /locus_tag="ACIZE5_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGC6107705.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(54893..55509)
                     /locus_tag="ACIZE5_000533"
                     /pseudo
     CDS             complement(54893..55509)
                     /locus_tag="ACIZE5_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
     gene            complement(55506..56294)
                     /locus_tag="ACIZE5_000534"
     CDS             complement(55506..56294)
                     /locus_tag="ACIZE5_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6107706.1"
                     /translation="MTVIGIILIIPLLWMVFTSLKPMEEIVRYPPTFFPEKIVWENYL
                     DTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYGFAKLDFPGKKLMFALVLSTMMI
                     PGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFNIFLMRQFYLSINNELIEAAEID
                     GANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFLGPLLYIQDQEKYTLQIGLQVFQ
                     NQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGMDLTGGSKG"
     gene            complement(56356..57267)
                     /locus_tag="ACIZE5_000535"
     CDS             complement(56356..57267)
                     /locus_tag="ACIZE5_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6107707.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(57308..58642)
                     /locus_tag="ACIZE5_000536"
     CDS             complement(57308..58642)
                     /locus_tag="ACIZE5_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6107708.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKIFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            58850..59680
                     /locus_tag="ACIZE5_000537"
     CDS             58850..59680
                     /locus_tag="ACIZE5_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HGC6107709.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(59924..60173)
                     /locus_tag="ACIZE5_000538"
                     /pseudo
     CDS             complement(59924..60173)
                     /locus_tag="ACIZE5_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(60364..60558)
                     /locus_tag="ACIZE5_000539"
     CDS             complement(60364..60558)
                     /locus_tag="ACIZE5_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107710.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(61063..61248)
                     /locus_tag="ACIZE5_000540"
     CDS             complement(61063..61248)
                     /locus_tag="ACIZE5_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107711.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(62098..62439)
                     /locus_tag="ACIZE5_000541"
     CDS             complement(62098..62439)
                     /locus_tag="ACIZE5_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HGC6107712.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(62439..62669)
                     /locus_tag="ACIZE5_000542"
     CDS             complement(62439..62669)
                     /locus_tag="ACIZE5_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGC6107713.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            62956..63294
                     /locus_tag="ACIZE5_000543"
     CDS             62956..63294
                     /locus_tag="ACIZE5_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107714.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(63499..64061)
                     /locus_tag="ACIZE5_000544"
                     /pseudo
     CDS             complement(63499..64061)
                     /locus_tag="ACIZE5_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
     gene            complement(64793..65374)
                     /locus_tag="ACIZE5_000545"
     CDS             complement(64793..65374)
                     /locus_tag="ACIZE5_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6107715.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(65557..66183)
                     /locus_tag="ACIZE5_000546"
     CDS             complement(65557..66183)
                     /locus_tag="ACIZE5_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HGC6107716.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(66205..67536)
                     /locus_tag="ACIZE5_000547"
     CDS             complement(66205..67536)
                     /locus_tag="ACIZE5_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HGC6107717.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(67691..68092)
                     /locus_tag="ACIZE5_000548"
     CDS             complement(67691..68092)
                     /locus_tag="ACIZE5_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HGC6107718.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(68178..68384)
                     /locus_tag="ACIZE5_000549"
     CDS             complement(68178..68384)
                     /locus_tag="ACIZE5_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107719.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(68479..69981)
                     /locus_tag="ACIZE5_000550"
     CDS             complement(68479..69981)
                     /locus_tag="ACIZE5_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HGC6107720.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(69999..70454)
                     /gene="argR"
                     /locus_tag="ACIZE5_000551"
     CDS             complement(69999..70454)
                     /gene="argR"
                     /locus_tag="ACIZE5_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGC6107721.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(70552..71169)
                     /locus_tag="ACIZE5_000552"
     CDS             complement(70552..71169)
                     /locus_tag="ACIZE5_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HGC6107722.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            71390..72763
                     /locus_tag="ACIZE5_000553"
     CDS             71390..72763
                     /locus_tag="ACIZE5_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6107723.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            72838..73950
                     /locus_tag="ACIZE5_000554"
     CDS             72838..73950
                     /locus_tag="ACIZE5_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGC6107724.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(74022..75659)
                     /locus_tag="ACIZE5_000555"
     CDS             complement(74022..75659)
                     /locus_tag="ACIZE5_000555"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HGC6107725.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(75827..76435)
                     /locus_tag="ACIZE5_000556"
     CDS             complement(75827..76435)
                     /locus_tag="ACIZE5_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGC6107726.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(76819..77970)
                     /gene="queG"
                     /locus_tag="ACIZE5_000557"
     CDS             complement(76819..77970)
                     /gene="queG"
                     /locus_tag="ACIZE5_000557"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HGC6107727.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(77989..78741)
                     /locus_tag="ACIZE5_000558"
     CDS             complement(77989..78741)
                     /locus_tag="ACIZE5_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107728.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(78882..79832)
                     /locus_tag="ACIZE5_000559"
     CDS             complement(78882..79832)
                     /locus_tag="ACIZE5_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HGC6107729.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(79833..80672)
                     /locus_tag="ACIZE5_000560"
     CDS             complement(79833..80672)
                     /locus_tag="ACIZE5_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGC6107730.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(80669..81415)
                     /locus_tag="ACIZE5_000561"
     CDS             complement(80669..81415)
                     /locus_tag="ACIZE5_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGC6107731.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            81653..83023
                     /locus_tag="ACIZE5_000562"
     CDS             81653..83023
                     /locus_tag="ACIZE5_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HGC6107732.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(83078..83974)
                     /locus_tag="ACIZE5_000563"
     CDS             complement(83078..83974)
                     /locus_tag="ACIZE5_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGC6107733.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(84088..84258)
                     /locus_tag="ACIZE5_000564"
     CDS             complement(84088..84258)
                     /locus_tag="ACIZE5_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107734.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(84255..84932)
                     /locus_tag="ACIZE5_000565"
     CDS             complement(84255..84932)
                     /locus_tag="ACIZE5_000565"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGC6107735.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(85023..85928)
                     /locus_tag="ACIZE5_000566"
     CDS             complement(85023..85928)
                     /locus_tag="ACIZE5_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HGC6107736.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            86103..87557
                     /locus_tag="ACIZE5_000567"
     CDS             86103..87557
                     /locus_tag="ACIZE5_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015486 -
                     glycoside-pentoside-hexuronide:cation symporter activity
                     [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide (GPH):cation
                     symporter"
                     /protein_id="HGC6107737.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVDPSH"
     gene            87573..88604
                     /locus_tag="ACIZE5_000568"
     CDS             87573..88604
                     /locus_tag="ACIZE5_000568"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGC6107738.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            88611..89798
                     /locus_tag="ACIZE5_000569"
     CDS             88611..89798
                     /locus_tag="ACIZE5_000569"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HGC6107739.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            89954..91336
                     /locus_tag="ACIZE5_000570"
     CDS             89954..91336
                     /locus_tag="ACIZE5_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HGC6107740.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            91373..91693
                     /locus_tag="ACIZE5_000571"
     CDS             91373..91693
                     /locus_tag="ACIZE5_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107741.1"
                     /translation="MGDCFCDGRTSQRYQKNEEEARKQPLPKQQMTLQEIDSILTEAF
                     LSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYFMIDHQPILWEDVRYIELKETKK
                     WFVT"
     gene            complement(91893..92561)
                     /locus_tag="ACIZE5_000572"
     CDS             complement(91893..92561)
                     /locus_tag="ACIZE5_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HGC6107742.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(92750..93547)
                     /locus_tag="ACIZE5_000573"
                     /pseudo
     CDS             complement(92750..93547)
                     /locus_tag="ACIZE5_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(93828..95207)
                     /locus_tag="ACIZE5_000574"
     CDS             complement(93828..95207)
                     /locus_tag="ACIZE5_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGC6107743.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            complement(95382..96551)
                     /locus_tag="ACIZE5_000575"
     CDS             complement(95382..96551)
                     /locus_tag="ACIZE5_000575"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGC6107744.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            complement(96526..97677)
                     /locus_tag="ACIZE5_000576"
     CDS             complement(96526..97677)
                     /locus_tag="ACIZE5_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGC6107745.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            complement(97637..98998)
                     /locus_tag="ACIZE5_000577"
     CDS             complement(97637..98998)
                     /locus_tag="ACIZE5_000577"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HGC6107746.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            complement(98995..99996)
                     /locus_tag="ACIZE5_000578"
     CDS             complement(98995..99996)
                     /locus_tag="ACIZE5_000578"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HGC6107747.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            complement(100012..100707)
                     /gene="dapD"
                     /locus_tag="ACIZE5_000579"
     CDS             complement(100012..100707)
                     /gene="dapD"
                     /locus_tag="ACIZE5_000579"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HGC6107748.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            complement(100713..101429)
                     /gene="dapB"
                     /locus_tag="ACIZE5_000580"
     CDS             complement(100713..101429)
                     /gene="dapB"
                     /locus_tag="ACIZE5_000580"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HGC6107749.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            complement(101426..102307)
                     /gene="dapA"
                     /locus_tag="ACIZE5_000581"
     CDS             complement(101426..102307)
                     /gene="dapA"
                     /locus_tag="ACIZE5_000581"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HGC6107750.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            complement(102310..103110)
                     /gene="dapF"
                     /locus_tag="ACIZE5_000582"
     CDS             complement(102310..103110)
                     /gene="dapF"
                     /locus_tag="ACIZE5_000582"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HGC6107751.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            complement(103097..104356)
                     /gene="lysA"
                     /locus_tag="ACIZE5_000583"
     CDS             complement(103097..104356)
                     /gene="lysA"
                     /locus_tag="ACIZE5_000583"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HGC6107752.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            complement(104571..104741)
                     /locus_tag="ACIZE5_000584"
     CDS             complement(104571..104741)
                     /locus_tag="ACIZE5_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107753.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            complement(104842..105405)
                     /gene="efp"
                     /locus_tag="ACIZE5_000585"
     CDS             complement(104842..105405)
                     /gene="efp"
                     /locus_tag="ACIZE5_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HGC6107754.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            105833..106750
                     /locus_tag="ACIZE5_000586"
     CDS             105833..106750
                     /locus_tag="ACIZE5_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HGC6107755.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            106763..107907
                     /locus_tag="ACIZE5_000587"
                     /pseudo
     CDS             106763..107907
                     /locus_tag="ACIZE5_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
     gene            108078..108536
                     /locus_tag="ACIZE5_000588"
     CDS             108078..108536
                     /locus_tag="ACIZE5_000588"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0043768 - S-ribosylhomocysteine lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HGC6107756.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            108695..109165
                     /locus_tag="ACIZE5_000589"
     CDS             108695..109165
                     /locus_tag="ACIZE5_000589"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HGC6107757.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(109218..109333)
                     /gene="rrf"
                     /locus_tag="ACIZE5_000590"
     rRNA            complement(109218..109333)
                     /gene="rrf"
                     /locus_tag="ACIZE5_000590"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT        30925 a        23098 c        19644 g        35724 t
ORIGIN      
        1 tcaacgtttc gagcaatgaa atagttatta acctacagac ccttccatct cataactgat
       61 caatcgattg agttcgactg catattccat tggaagttct ttggtgaatg gttcaacaaa
      121 gcccatgacg atcatttcag ttgcttcaga ttcggtcagg cctcggctca tcagatagta
      181 gagttgttct tctgagattt ttgagacttt ggcttcgtgt tctaaagaga cttggctgtt
      241 gtggatctca ttgaatggga tcgtatcgga tttcgaccat tcgtccatga tgatcgtgtc
      301 acattcgata tgagagatcg aacccgcact gtttttggca aaggttactt gtcctcgata
      361 gtttacttct ccgccgtctt ttgaaattga tttagagacg atagagctag atgtatttgg
      421 tgcattgtgg atcatttttg cacccgtatc ttggatttgg tttgctcctg caaaggcgat
      481 ggagagcatg gtgcctcgtg caccttttcc atctaagtaa acacttgggt atttcatcgt
      541 tgtttttgca cctaggtttc cgtcgatcca ttcaacggtt gcgccttcgt atgcttttgc
      601 tcgtttggtt actaagttgt acacattgtc tgaccagttt tggatcgttg tgtaacggca
      661 atacgcatct tttcttgtaa agatttctac gatggcggca tgcaggctgt tacttgaata
      721 agtaggtgcc gtacaacctt cgacatagtg gatgcttgct ccttcgtcaa caatgatcag
      781 cgtacgttcg aattgccccg tgttttccgc attgatccgg aagtacgttt gtaatggaac
      841 atcgactttg acgccttttg gcacgtaaat aaaggtccca cctgaccata cggctgaatt
      901 cagcgctgct aatttgttgt cggttggcgg tacaagtttt gaaaagtact ctttgaataa
      961 ttcagggtat tctttcaaag cagagtcagt gtcagtaaag acgattccta acttttcgaa
     1021 ttcatctttc atattatggt acacgacttc tgattcatat tgtgcggaag caccggctag
     1081 ataagctcgt tcagcttctg gtataccaat cttttcaaat gtatctttga ttttttctgg
     1141 tacgtcttcc cagtcacgag cgggtttgtc acttggtttt tggtaatatt tgatggcatc
     1201 gaaatcgatg tctgaaaggt cggggcccca tgtttgcatt ggcattttgt taaatgtttc
     1261 tagagatttc agacggaatt caagcatcca ttctggttcg catttgattc ttgacatctc
     1321 acggatcact tcttctgtca agccttctcc tgtactgaaa accggttcga catcatcgtg
     1381 aaacccgaat ttatattctt ctaattctgg tacgcccatg ttctcactcc tcttccttgt
     1441 ggtaatgatg gaaagctgcg gtaccatcgt tttccattgc ttttcctagt gctttccagg
     1501 caagtgtcgc acatttgatc cgagcgggaa atttagctac accaccaagc atagcagcat
     1561 cgcctaattg gtcgggatct ttgacttctt ttccttggac aagctgtaga aagtctacag
     1621 ttaaatgttc tgcttcttct attgattttc cgatgacggc gtctgtcatc atcgaggcac
     1681 ttgccgtact gatggagcag ccactgccgt caaaggcgat atttttgatg attccgtctt
     1741 ttacatcgac ttgcaattcg atcacatctc cacatgtggg gttgttcaat tcgatcttgc
     1801 ttgtcgagtc agtcaagctt ccacgatgat gcggatggga agaatgatcc aagatcactt
     1861 gacggtataa attgtctaat ttagatagtc ccatgttgga aaaactcctt tgttgccatg
     1921 attgcttcaa ctaaacggtc ggcgtcttgc gttgtgttgt agaaataaaa gctcgcgcga
     1981 gcagtcgctg atacttcaag gtacttcaat agcggttgcg cacaatgatg acctgctctg
     2041 acggctaccc cttccatgtc taaagctgtc gcgacatcat ggggatgtaa cccatccaaa
     2101 ttgaatgcaa cgactcctgt ccgaaaattc gggtcttgtg gaccataaac agtcaatcca
     2161 tcaattgctt gtaattttgg caacacataa gcggctagtt cttcttcata tcgatggata
     2221 ttgtccatac cgagtttttg caaataatcg attgcatggc ctaatgcgat agcgccggcg
     2281 atatttggtg tccctgcttc gaatttccaa ggtagttctt tccatgtact gtcgtataat
     2341 tcgacaaaat cgatcatttc gccaccaaat tcaacaggtt ccatttcttc taaccatttt
     2401 cgtttaccat ataaaacacc aatacctgtt ggtccgcaca ttttgtgtcc gctgaaagca
     2461 aagaaatcac agtctagtgc ttggacatca atggccatgt gcggggcaga ttgagcacca
     2521 tctactacga tgaccccgcc gttttcatgg acaagttcag ctaattcttg aacaggattg
     2581 aagacaccta agacattgga tacatgagca atggagacga ttttggtttt gtccgtaatc
     2641 tttttcgctg catcctccat atccaggaag ccttcttctg ttagttcgat atatttcaag
     2701 acagcacctg ttcgttttgc caactgctgc cacgggataa cattagaatg atgttccatg
     2761 taagagagca ctatctcgtc tcctgctttg atatagcggt cgccgaaggt tctggctacc
     2821 caattcaagc ttgtcgtcgt accacgagta aacagcactt ctgctgtttc ttttgcatgg
     2881 atgaacgccc gtactttttc tcttgcttgt tcataatcat gggtcgcgcg ttctgctaac
     2941 gtatggacac cgcgatgaac attggcgtta tcgtgttcgt aatagtacgc taatgcctgg
     3001 agtacttgtt ttggcttttg ggtcgtcgct gcattatcca gataaactaa aggttcatca
     3061 ttgacgtctt gaaataagat aggaaaatca ttgcgtagct ttttagcatc gatcatccat
     3121 tcaacttccc ttcgattact tcgactaatt ctttccgaac ttgttctaca gggattgctg
     3181 ttaagacaga accgaggaat cctcgaatca ctaagcgctc tgcttcttct ttatgcaatc
     3241 ctctactcat cagatagtac atttcttctg gatcaactcg tcctacactg gcagcatgtc
     3301 cagcagttac ttcgttttca tcgatcaaaa gaataggatt cgcatcacca cgtgctttat
     3361 cagaaagcat caagacacga ctttcttgtt gggcatctgc accttttgcc cctttcaaga
     3421 tgtggccgat accattaaag gtcaatgttc ctttttctcg gatcactccg tgttgcaaaa
     3481 tatgcccgat cgtatgaggg gctttattgg ttactcgtgt atcgattcct tggatttgtc
     3541 tgcccgagct gattgccacg attttgactt ctgcgtgtgc accttctcct gctaaatctg
     3601 agtcaaagtc agcgatcaca tgaccgtcat tcatgacacc aattgcccag tcgacagaag
     3661 catctcgtaa aatgtgccca cggcgattca tataagaagt aatattttct cctaattgat
     3721 ctacggctga atatttgatt tttgaaccag ctttagcgat gacttccacg atgatattac
     3781 ctgatgattt tgctacttgt tctttggttg tctggaaacg ttccagataa gaaaattcac
     3841 tatgttcatc tgccacgatc aacacatgct tgaagaagtg ctcatcggat gcgccatctt
     3901 gaatgaataa ggactcgagt ggttcatcga tcacgacatt tttaggcaca tacaggaaaa
     3961 taccgctgtt cataaaagct acatggagtg cagtcaattg gtcttcgttc atgtttactg
     4021 cttttttcat ataatattct tggactagtt ctggatattc gatcattgca gtgaacaagt
     4081 cggtaaaaat gactcctttt tctgctaatt ccacaggcag ttgttcaaaa atcgtccatg
     4141 aaccttgttg gacaagcaca ggattgtctt tcattgcatc aaatgccgga atcgtgcctg
     4201 tttcactgat ggtttgtgtt tctttcacat caaataacga ccagcgatgg aatttcaccc
     4261 gatcgatatg cggcaatggc agttcatctg ctttcgctag tgcgtcttga cggaaggttc
     4321 tcatccaatc aggttcgcct ttacttaaag aaaaatcatt taccgcgtca agataatcga
     4381 gccagttttt ttctttcatt cttgctcccc cttacgcttc ttcttcttta tagtcgattc
     4441 ctaattcttt actgatacca gcgtagcctt ctgcttccag acgtttagct aggtcagcat
     4501 tccctgtcat gactactcgg ccttccatca tgatgtgaac gacatcaggt gtgatatagt
     4561 tcaataatcg ttgatagtgg gtgatgatca atgcaccgaa attgtctccg cgcatttcat
     4621 ttactccttt agcaacgact ttcaaagcat cgatatccag acctgaatcg atttcgtcta
     4681 aaattgcaaa tgtaggttct aacatcaaca attgcaggat ctcattccgt ttcttttctc
     4741 cgccagaaaa accttcgttc agataacgtt cagccatttc ttctggcata tttagtaaag
     4801 ccattttttc atctaacttt ttcaaaaatg ccataacaga aattttgtcg ttttcatcac
     4861 gtttcgcatt gatcgctgca cgcatgaatt ccgcattcgt gatacctggt atctcacttg
     4921 gatattgcat agctaaaaat aagccaagtc gcgcacgttc atctacttcc aagtctaaaa
     4981 catttttccc gtcaaacaaa atttcgcctt ctgttacttc atagtttgga ttgcccatga
     5041 tagcggcaga taaggtagat tttcctgtgc cgttaggtcc catgatggca tggatttctc
     5101 cggttttcat tgttaggttt acgcctttaa ggatttcttt ttcctcgatc gacacatgta
     5161 gattttttat ttctaagaca gacatgcatt atacccccaa attctctttc gttctcactc
     5221 attttagact aattgagaat gaagcgcaat gaccttcctt actaaaatca aatatctttt
     5281 atttattatt aaacaatttt gatttctaaa ttagaatagg tataaaaaag atgagaaata
     5341 agccattaca gacttatttc tcatcttttt tgttccatac cttattttgc atcagccttt
     5401 actggtttaa cagagccgcc ccatttgtct gtgatccatt cttggacttc tttgcggtga
     5461 agcacttcaa tcagtttttt gattttgtca ctgtcttcat cacctttacg agtcgcaata
     5521 atattcacgt aaggagagtt gtccttttca agcaatacgg catcttctaa tggattcaac
     5581 cctgcgccgt aagcgaagtt tgcgttgatt gcaactaggt caccttcatc attttggtac
     5641 gtagaagcta aaagtgatgg gtcgatcgta tggttgaact tcaagttctt agggttttct
     5701 tcaatatcat cgaatgttgc tgtttccaga tctactccat ctttgacttt gactaagcca
     5761 gcatcttgta gaattgtgat gatgcgtccc cagtctgatt cagaatttga agtaatgatt
     5821 gttgcaccat cttttaattc ggaaacatct ttgacttttt tagagtacaa gcccattggt
     5881 tcgatgtgga cagcaccggc attgacaaag tcatatcctt tttctttgat ttctttgttc
     5941 aaataaggaa tatgctggaa gtaattggca tcaatgtcgc cttcttccaa agattggttc
     6001 ggtaatacat agtcatcgaa tttgacgatt tcaagatcga ttccttcatc tttcaataat
     6061 ggtttcacat gttccaaaat ctctgcgtgc ggtgtcggtg aagcgccgac tttcaatgtc
     6121 gtgtcgtctg ctttatttgc tgaatctttg ctgtcgctgt tgttaccgca tgctgctaat
     6181 cctacagtca gcaaaagcgc tgctgcaaat ccaaaaattt tctttttcat atcctacatc
     6241 cccctatatc ctattatctt ttgtctgttt tcttagttaa gaaatcaccg attccttgaa
     6301 cgataaatac gattagtaaa ataattaaag tcgcaacgaa tgtcactgtt agattaccac
     6361 gctggtagcc ttcctgccaa gcaagacctc caagtccacc tgcgccgatc gcgccggcca
     6421 tcgcagtaaa tccgatcatc gagatcgttg taactgttaa tccagaaatc aatgcgggaa
     6481 tactttcagg tatcaagacc ttccagatga tttcccagta acttgctccc attgcatctg
     6541 ctgcttccag tacaccaggg ctgacttcac gaaaagcaat ctctactaga cgggcataaa
     6601 atggtgctgc ggataaaaca agagctggaa tggctgcttg cgcacctagc atagtgccta
     6661 cgattgcttt agtaaatgga atgatcaaaa ccatcaggat cataaatggc gttgaccgga
     6721 aaatattact gatgatcgat acgattccat aaatgattcg agcatacggt ttgtttttgc
     6781 gtccaataga gtaaaggatc aatcccaaaa ctaatccgat gatcgtcact aagaccattg
     6841 agattaatgt catatatagt gtatcaagga tagcctgatt catcgtttcc gggttgattt
     6901 gtttaaaatc tagatatgtt tctgaaaagc ttttatccac gatggatcac ctcaattcct
     6961 actccttgtt ctttgatgaa cacttctgct tgatctaatt ctttggtttc accagtcatc
     7021 aagacagtca atgaaccaaa ggaaccttct ttcacttgtt tgatctttcc atacacaacg
     7081 ttgacatcga tgttatagcg tcgaatcgct tgggaaatga ctggctcgtt ggcatttctt
     7141 tcgctaaagg tcaaagttgc caaacggccg cttggatttt ctttgatgag ttcagctaat
     7201 agttctgtcg aatcagcttc tggttcgatg tcttgttgta caaagcgttt ggttacttct
     7261 tttttcggtt gtctgaagac agtcaatacg tctccttctt ctacgacttt ccccaactcc
     7321 atcacagcga ctttgttgca gattttgcgg atcacattca tttcatgtgt gatcaagacg
     7381 atggtcaaat tcaatttctt attgatcgct aacaataagt ctaatacttc ttctgttgtt
     7441 tgcgggtcca atgcgctagt agcctcatca caaagcagga tctcaggatc atttgccaat
     7501 gctcgtgcga taccgacgcg ttgtttctgt ccgccggaaa gttgtgaagg atatgcttgt
     7561 ccgcgtcctt ctaacccgac taaacgcaac agttcttctg cccgttcttt acgtttgctc
     7621 tttggtacgc cagctaattc cagcggcagc tggatatttt caagtacagt tcttgaccat
     7681 aacaggttga aatgctggaa gatcataccg attttctttc ggaatgtacg taattctttg
     7741 ttttttaatt ttgtaatatc ttgatcgttt acgatcactt cgccgctcgt gggaagctca
     7801 agtccattca ggagacggac taatgtactt tttcctgcgc cagaatagcc gacgattcca
     7861 taaatatccc ctttttcaac gtttagtgaa acgtcattga cggcttggat gtttccgttt
     7921 ttcccattga atgtcttttt gacattcgtt agttggatta atgacatgcc attcacatct
     7981 ttctcttata atttttcaaa caaaaaagcc ttcgccctct tgccttaagc aaaaggacga
     8041 aagcttgaac ttccgtgtta ccaccttgat ttaccgttac ttcgcaataa cagcctcttc
     8101 cagtacttgg acttagcttc tttccgtata ctgtcgcgct gtaacgggca ctcccgtagt
     8161 aagtttgctt acgctcgctt actctgctct aagaccatct tccatctcat tttcgttacc
     8221 cattttcagc aaacagggct ctcttcaaac gtccgtgaca tgtactcttc ttttcaaagc
     8281 tttctcgttt catataggat tgcttatgat tatagcaact ggaagaatca gtgtcaactt
     8341 ttttcaagtg attttctgat tttataattc gtcaaattct tttggatcaa catctttgaa
     8401 acttaagatc cacgcattca tttcatctga atcattcaag atattgatat cttcaccgat
     8461 tttatcatta acagaagaaa ctgtacccgt tagcgggctg gcaaattcat tgaccgcttt
     8521 ttccgcttca acttcgatca gaggttcatc tttttttagc gattgtcctg cttttggcag
     8581 attggcaaac gtgatgtctc caagttcttc ttgcgcttca tttgtcaaac caacacagta
     8641 ttcttttcca ttaaataaga tccaaaggtt gtcctttttc ttcaaatgct tgcctgccat
     8701 tttatatcag ttctccttca taaatttttt cattgaatcc aattgcaaca agctggtcct
     8761 ctcgtaagat cagtggtcgc ttgatcagca taccatctgt cgataagact tggctcgctt
     8821 ttgaagccgt aaactcgcct acttgatctt tcagtccaag ttcccgatat ttcatcccgc
     8881 ttgtgttgaa caggcgacgg attggtactt gactcgtttc tagccaagtc tcaatcgttg
     8941 aggccttcgg tacttctttg atcatatcaa cggtttgata actaacgcca tgctggtcta
     9001 accacgcttt ggcttttttg catgttgaac atttcgggta ccagtaaaag gtgtacaatt
     9061 ttcttacctc cttgaagatc ttgcaggtgc ttcattttgg tatctcatcg ataatatcaa
     9121 cccgataccg atcatgttcc ctaaaatcga ggatcctccc tgactaatga aaggcaatgg
     9181 gatccctgtt aaaggaagta atccgatatt tgctccaata ttctcaaaga catggaacag
     9241 cagcatcatg atcaaaccgc ttgcgatata ggcgtaaaat tcattattcg tatcgaaaca
     9301 cacccgaatc atacgataga ttaaaataaa atacaagaaa atgacgaatg caccaccgat
     9361 aaagccgaag ttttcaccga taacggtaaa aatcatatcg gactcacgaa caggcacata
     9421 gatattgctt acgttgaatc ctttaccaaa caagccaccg gtaccaattg ccaaaagtcc
     9481 ttgggccggc tgataactca ttcctgacgt atcatggaaa gggtccagcc atgaatcaat
     9541 acgtgcaaac tgataagatt tgaatccaac tttataaagc aagtctcttc cgccttcagt
     9601 cgtaaccaag aagatcgttc ctgctccaac gactactgcc aagattacta caggtgcgat
     9661 gatgcgccaa gagattccag acatcaggaa aatcccgcca aagatcgcaa gaaagacaag
     9721 catcgttcca aagtcatctt gggccatgat caatgctaaa accggtattg tcacgatcaa
     9781 gagcttccca atcagccaaa agtccgattt catcgtccgt tcttttactt gcgtattatg
     9841 tttagttacg atcagtgcca tcatcaagat gtacgcaatc ttcatcaact ctgctggctg
     9901 gaaagtaaac gcaccgaatc gaaaccagtt tttagaccct gttgaagcag ctaaattctg
     9961 atcatagaat ttgagcaaga gtcccattac cactaacccc aaaccataaa ggtaaggagt
    10021 cagtttccag atccatttgg aattcaaatg catgatgaca acgattgctg ccgctccaac
    10081 taaataccag acaacttgca tccctacgcc tttcaagact gctggattgt tcggatcatg
    10141 gctaagtgct acatataatg agagcagacc aatcaaacat aacagaaaga ctggtaaaat
    10201 cacgccataa tcaatacgat tatcgttcga agcttttaat tttttttcca tgtttcatcc
    10261 cttttcttaa aaaccatact gctgattatt atagcggtcc agttagataa tggaaagtct
    10321 ttccatagac atttgggaaa aattaacttt ccgtttgtgc agttgcttga gcaaatgcag
    10381 tacaaaagcc tactgcttat ctttagtgta tcatagaact ttttttgata catgcaatta
    10441 tctaccagct gagattctcc tcgctgtgag aagtttctgt gctttcattg tatcgaagga
    10501 tctcttcggc aatctctagc agctgatcag aaaccagatt ggttcgttgg atgaaataaa
    10561 aatatcgatg gaaattcaac ggagtcattg gcacattttc tggaacagag cgcttagaca
    10621 aaatcgagcg accgattcct tccttcagca acgcaacaat tacatcgtta cttttcacga
    10681 tcatcttctt atcttggata ttcatctctt caaaataacg ctgcgtgtaa tgaaaaacac
    10741 cagagtttgc ttctcttaca agccacaatt tgctttttgg gtccccagcg atgactagct
    10801 ggtcttccat caaagagtat ctttgtacgc cggaagtctc taatggcttt tcgataaaac
    10861 caaaatcgga ttcatgtttc gctacttgtt ctaatgattc atgagaattc gtgatttcga
    10921 tctcaaaatg cactttagga aaccttttga tcagatgttt catcaactga ggcaaaagat
    10981 agacagcaaa ggtgtgggaa gcaacgatcc gacatacttc ttcttcattt tgttcattga
    11041 gcaatttttg ctgagtttct tcccattctt ctaacaaaac cagtgtccgt tcatataata
    11101 agtcggcttg cttagttgga agcatctctt ttcttccgtt acgttgaaaa agatcgatat
    11161 tcaattcccg ctccaactgt ttgatttgat tcgagactgc tggttgagat aaaaacagta
    11221 cttctgctgc tctggaaaaa tttcttgttt catatactgc tcgaaaagtc gttaataact
    11281 taaacatggc accacttcca taacttttta tgataattac tataaaaact atttgattta
    11341 aatatacaaa aaaccatcta taatagaaat gtacaacaaa acagttgctg atccaactag
    11401 taacttagat gaagacaatc agctgtctgc ttgctcgtaa tcatacattc ctattcattt
    11461 tacaatgtat tcgttcatct tggtactaaa atctattaaa taaaaaggag aatattatat
    11521 atgaagaact ttttgaaaat tattccgatc ccgatctgcg ggttgatcct tgggttagct
    11581 tcccttggaa atctgtttaa agactatcac catgttgctt taggcaatct aactggcggt
    11641 atctctatga ttcttatgat attcattttt gttaaattgt ttatcttatt cgaacacacg
    11701 aaacaaacgt tgcatgatcc aatcatcgcc tccgtttcac caacttttac gatgtcactc
    11761 atggttattt gtacttattt tgtttcatat gaaagtattg caccaattgt caaattcatt
    11821 tggctgtgcg ctgttatctt ccaagtgatc cttgtctttt atttcaatta tcaccatgtt
    11881 atcaaagctg atctttcaat tgaagcaatt tatccaagct ggtttatcat ttacgttgga
    11941 tttggggtca tcactgtaac tgccgggaac ttcttcccac ttattggaaa aattttcttt
    12001 tggatttcat tgatctgcta tgcgttctta ttgccgatca tcatcaaacg tgtctttttc
    12061 gtaagaaata tggctcatcc gacacgtccg ctgattacga tcgttgcagc acctggttct
    12121 ctttgcctaa caggttatct taaaaacttt gctgaaccta atttttatct tgtcgtagca
    12181 ttgttcgctt tatctcaagt attgtatttc gttgtgctgt ctatgcttcc acgtttgttc
    12241 aagcttcgtt tttatccaag ctatgcagcc tttacattcc cgcttgttat ctctgcaaca
    12301 gctatattta ctactgttca ttacttcaac agtttaggta tctatagtag cgtattggat
    12361 ttcttaaaag ttgcggaatg tctgtttgca agtgtagttg tcttctacgt tcttgctcat
    12421 tacgtacgtt tcttaattaa agaacatagc aaacatggaa aatttgtttc taaaaaaatc
    12481 gcttaataat cgattcaata ggttgtgaaa aagctgttct gcatcaagta ataagaacgg
    12541 ccaaacaaaa acagctgttc atgtttttgt actggttggg cttattaccg cagatgcaag
    12601 cttttgaaca ccgtttacca agaggtcgta aaagaagtgg tcagcttcaa gaaataagaa
    12661 ggaatttacg aaaattgctt ctcaaatttt tgtgaaattt cggcttattt ccgtagaagc
    12721 tacttctgga acaccgttta ttcgaaacaa gaggtcgtac aagacttttg tcacgacctc
    12781 ttgttctttt gtcaaaatac tggtttagtg ctactatgtt cgagtatgct tttagtattt
    12841 attgacgaaa ggaaccgatc aaatgaaatc attgtcacat ccaataaaat ctgtaaagga
    12901 ttcagcggtc cgcgaaatct tacccggttt actgctttct tttgccatcg ctgccttcag
    12961 caggcttctt gctatttatc tgccacagtt aggtggagcg actattgcta ttttattggg
    13021 tattttatta ggaaatactt tttttaaaca gcctgttcta gcaatcggca caaaatttgc
    13081 tgaaagcaaa ctattagaat tctctgtttt tttactaggt gcaactgtca cagctcaaac
    13141 gattgctcaa attggtgtaa aaggaattgt ttttgtgtta ctgcaaatgt cagtcactat
    13201 catcggtgct tacttgattg gtaaaaaact gcaattcagc gatacttctt ctttgatgat
    13261 ggctggagga aacgctgttt gtggttcttc tgctattgct tcaatcgccc cttccatcca
    13321 tgcgaaagag gaagaaaaag gacagatcat cacactagtc aatctactgg gtactgtgat
    13381 gatgttgact ctcccttttc ttggattaca gttgtttggt ggaaatctca ttgaaaaaag
    13441 tgcacttttg ggtggtacac tccaatctgt tggtcaagta gtcgctgggg caagcttact
    13501 tgacaattct gttgtcgaat tcgccatgct atttaagatt ctacgtatta tgatgctcgt
    13561 tgttgttgtc tatctgtttg aaaaattcat gcacaagaaa caaccagctc tgtttgaaac
    13621 gccaactgat acgcagaaaa aacgaaaatt accgcttcct tggtatgtat tagggtttgt
    13681 gatcttttgt ttggtcaaca gcttgttttc tttacctgta gttattgacc aatcggcaca
    13741 ttttatcagc agctggtttg agatcactgc tttagcggca attggtctgc gtttagactt
    13801 tgcaaaattc atgaaagaag gtacacgctt cttatcttat ggattagctg tcgggcttct
    13861 ccaaacagtg atggctttac tatttatttg gctgatcaaa gtttagaatg aacatgaaaa
    13921 aacagttgtg attctcgcat ggaacaatgt ccgaatcaca actgttttta attttgcaga
    13981 tatccttcta acaacaacaa ttggcgtttg atttcaaccc catctattgc gtttcccata
    14041 tatcctgtca gttttccatt ttgcccgatc actcgatgac aaggaataac gattggcaat
    14101 ggattggttc gatttgcctg cccaatcgct cgcacagctt tcggactatc aacagcaacg
    14161 gctacttctt tatacgttcg gatttctcca taaggaatgg tcgacaaagc tttccagaca
    14221 ttttgctgaa aaggcgtacc tctctttata gataaaggaa catcaaattc ttttcttttt
    14281 cccgcaaaat attcttcaaa ctgttcttgt gtgcgcgtta aaattcgctg attcgctgat
    14341 tcgctttctg aaattggctg aaaagataca gcagtcaatc cggattcatc tgcatctaac
    14401 cataaaaagc cgataggtgt gtgtattttc attttgtttg ctcctagtca atagactgga
    14461 acttcctcct ttttctctat ccaaaactac ttgccaacta ataaaaattg ttcttaaaag
    14521 tttgataaac cgaggaaaca tggtaaacta aatacgttag tttacaaaaa gaatacctgt
    14581 tcttttacgt aaaatcaaat tttaaaggtg ttatttaagg tttattaaat tttgaatgta
    14641 aaccatatat aaacatacga ttgaaaggat agaaacgatg aaagtatcaa ttgttgtccc
    14701 atgttttaat gaagaaaaaa ctgttcctct tttttttgat gaggttgaaa aattcaaagg
    14761 tgcccatgag ttcgaatatt tgtttattga cgacggatca aaagacggta cgttagcagc
    14821 aatcaagaag ctagcctcag cttatcctta tgtccgcttt gtctcatttt ccagaaattt
    14881 tgggaaagaa gcggctctgt acgctggatt gcaagcttct acaggagatt tagtgaccgt
    14941 gatggatgtt gatctgcaag atccgcccga actgcttcct gagatgatca accggatcac
    15001 tacttctgat atcgattgtg tcggcacccg gcgttcgact cgtgaaggcg agcctgcgat
    15061 acgcagtttc tttgcgaaaa aattctacca gttgatcaat aaaatcagcg atacagaaat
    15121 ggtcgatggc gctcgtgatt tccgcttgat gactcgtcaa atggtggatg ccgtcctaga
    15181 attaacagaa tacaaccgat tttcaaaagg attatttagc tgggtcggat ttaaaacaga
    15241 atatatttct tatgaaaacc gcgaacgtgt ggctggcgaa acatcttggt ccttctggaa
    15301 attattcaac tactcgattg atggtatcgt gaacttctcg gatgcaccgt taacgattgc
    15361 ttcatttatc ggcgctttgt cttgtgtcgg ttctggtatt gcaattttgt tcattatttt
    15421 gcgggcattg ttgtttggtg atcctacatc aggatggcct tccatggtct cgatcttcct
    15481 gttcattggt ggaatccaat tgttatgtct tggaatcatc gggaaatata ttgggaaaat
    15541 cttcttagaa acgaaacagc gtcctgttta tatcataaga gaaacagaaa aagtgaagcc
    15601 aaatgaattg aagcctcacc aataatatac gtcaaatgaa gtaaacattt ttttaaatga
    15661 aaaaggactg tgacaaaagt cttgtcacag tccttttttc cgaataaatg gtgttccaga
    15721 agtagcttct tcggaaataa gccgaaattt cacaaaaatt tgagaagcaa ttttcgtaaa
    15781 ttccttctta tttcttgaag ctgaccactt ctatcacaac ctctttcata tcttattact
    15841 tcttcattgc tgcttttagt gctgctgcta atgggctttc ttctggttct tctgcttgtg
    15901 catatttttt cagcaagcgt cgttcttcat gtttggtcat tttcttcttc tgctcttttt
    15961 tatcaagcaa tttttctgtc gttccatcgt atttacaacg gaaataagca ccgtttttac
    16021 cttcgatgat ttccattttc cggtgacatt gcgggcatcg atgattagag acttttggat
    16081 cttttcttct gcggtagttg caatctgaat tggtgcagac atagattttg ccgtcacgtg
    16141 tgtttttctc gcgcagattg gccccacatt ctgggcattt cttttgggta atcgagaaat
    16201 cttgatattc ttgtttgctt gatttgatct cattcaccaa gcgttttgtt tctttttcga
    16261 ttccattcaa gaaggttcct gcttgtttct ttcctgcagc aatagcttca aggtcttttt
    16321 cccagctttc tgtcaaatct ggtgttacta aagagggatt taccaatact aataattgct
    16381 tacctttagg agatacttgc agtccttgag gggtacgttc catcagttca gatttgatta
    16441 gtttctcgat aatctctgca cgcgtagctg gggttcccag actgtatttt tccatttgac
    16501 caagcaagct tgcttctgac aatggtttag gcggtgcaga tagttctttt ttgatggcga
    16561 aatcgggatt gattctcatt cctttttccc atttgactgt ttccgtctca gtttcagttt
    16621 cgcctttcca tcctgcttgg acgacacgat tttgccgaaa aatgaatcgt tctttaccaa
    16681 attcaaccgt aacttttgtt tggctgactt tatggggttg agcaaacagt cctaaaaaac
    16741 gagagacaat catttgatag atttttcgct cttcattact taatttttca taacgtgctc
    16801 tgttttcagt tggcaaaagt gcatggtgat cggtcacttt actgtcttgg aatacttttg
    16861 tctgttggac gatggctccg tttttcaaat actgcttgac ctcaggagca aagtcgctga
    16921 ctgcttgcaa tcgttctttc atcgtacttt tcatgtcatt tgtcagatat ttgctgtctg
    16981 tacgcggata agtaacgatc ttatgggtct catacaaact ttgtacaaga cttaatgttt
    17041 tctttgcaga atagccatag cgttgattgg cttctctttg gatctctgtt aaatcataag
    17101 gcaatggcgc agattccgtt tttaattttt cttggacttc tgtgacagtt cctttgcttg
    17161 tactgatcaa ttgaacaagt ttttgtgctt cttcttgtgt ttttaaagca aattgatttt
    17221 tttgaagcat tttggcttgt tcttttccag cttgcaacgt gatcgtgaaa tacgtttgtg
    17281 gacggaactg ctcgattttc ttttcttggt ctctcactaa tgctagtgtc ggtgtctgca
    17341 cacggcctgc tgataaatta tccgcgtact tcacagttaa ggctctggtc acattcaatc
    17401 ctaccagcca gtccgctttt gcccgggcaa gagcagattc atacaatgca tcatattctt
    17461 tcgcaggtct tagttgcttg aatccagttt tgattgcttt atctgtttga gaagagatcc
    17521 ataaccgctt cactggttta ttgaaatgca catactctaa gatccagcga gcaacaagtt
    17581 ccccttctct tccggcatct gtcgcaatga ctgcttctga gacatctttt cgctgagcca
    17641 gctgcttgat tgcttttaat tgatgtcctg ttttaggaag tggtttgatt cctagttttt
    17701 tagggatcat tggcaacgtg tccatttgcc agctctgcca ttccttattc agatcttccg
    17761 gcattttcaa tcctaataaa tgaccaaggg cccaagtaac gatcaccttg ggtccttcat
    17821 aataattttt gtgcttttga ttagcaccaa gcaccttgct taggtctttc gcaacgcttg
    17881 gtttttccgc tagaattagt tgtttcataa aattcctttc tgctttctac tgtgatgggc
    17941 tgatgatttt tcaacaacgc aagtcccttg tattgctgta aatcatcgtc acactcttca
    18001 caccagcgct catctccgtc attccaaaag gcgctgagaa agttactttt tgcattgata
    18061 tattcataat tttgatggat ttcgttccat tgtttttcgt acgcttgtcg tgcttcttcg
    18121 aaagactcga atgtttcttc ttcttcaata tcttcttccc agtcttcaaa aaaccaccaa
    18181 ggctcattgt ccccgaacat ggtaattact tgatacatac tcgtgctcct tctttcagct
    18241 tttctagact catcttagtc acttttcaag aaagttgcaa gaattttctc ttataaaagg
    18301 gtcatttaat gaacatctta aaattgttac aaatgaatct gattgtttaa ggcaaagtag
    18361 cgataaagtt attgatcatc caaaaatagc tgtcttctgg atcgattgtt ggttcttttg
    18421 taaagtatcc taaaaaacgt aaggaaagat aaccgtggat catactacga agttccctgc
    18481 ttcgatgaac tttttcttct ttcgttaatt gaaaagcctc aaatatctgc aaaatgatct
    18541 gattcgtttc atggattcca tctaataaaa cagcttcatt ggtatgcggt acactgatca
    18601 gtaactcata cactgcttga tttgaaaaag caaaggatcg ataagtttct gcatagatct
    18661 gcagtgcttc ctgaccactt tttcccacaa gagcccgtcg cagctggtca ttaagttcct
    18721 gcagaagttt cgctgttagc gctgttttga catcacgaat atttttgaaa tggttataca
    18781 gcgagggagc cttgatatcc aagcgtttgg ctaaatgctg aaaggttatt tgctgaacat
    18841 ccatctcttc tgctagttct cgaaagcagt cgatgatttt ctcttgagac agatttcttt
    18901 ttttcatttc catgtttcct ctcataaaat aaatccttca ctctttcagt ttaccacgaa
    18961 aaagaaagag aaaaaagaga ctttcattga taaactacat attgtagttt ataataaaga
    19021 gctgtagatg aaaattttca gaaagaagga gtctaattgg ctgcaagaat aaaggaaaaa
    19081 ttatttagga aaagagaaac ttgggaacaa aacttgtttg tcttatggtt tggaacattt
    19141 atggctggta tcggatttag tttagtcatg ccttttatgt cactttacat agatacgtta
    19201 ggtaattata gtacgtcaca attgaacttt tggagcggat tgactttttc atctactttc
    19261 ttggtgacta cgcttatctc tccttggtgg ggaaaattag ccgaccaaaa aggaagaaaa
    19321 ttgatgctgt tgcgtgcttc attaggaatg gcaatcgtca tttctttgat gggttgcgtg
    19381 actagtgtgt atcaattagt cgcattgcgt ctgcttcaag ggattttttc tggttatatc
    19441 agtaatgcca ctgcccttgt cgcaactggg acgccaaaag aaaaaagtgg tcaagttctt
    19501 ggaaccttag caactggttc tgttacagga acattacttg gaccgcttct tggcgggatc
    19561 tctgcttcag cgtttggcta tcgccctacc tttttcatta cagggatcat cttatttttc
    19621 gtcttcttgt tgagtctgtt tttcgtccat gaaaaatttg tcccagtgaa aaaagaaaac
    19681 atggtttctg ccaaacagat tttcaaagac ttgaaatatc cacacgtcgt catcggtatg
    19741 ttcgtcacaa cgatgatcat ccaagcatcc aacaattcca ttagtccaat catcagtctg
    19801 tacattcgcc aattgctgca tggacatggg aatgttacgt tgatcagcgg aatcattgct
    19861 tcgatacctg ggattgccac tttgatagcc gctccaagat ttggtcgctt aggtgacaag
    19921 attgggagtg aaagaatact tgcgattggt ttgggttttg cgattctggt ttatatccca
    19981 atggcattcg tcacgaatgt ttggcaatta gctgccttac gttttttgat tggtatctct
    20041 gatgcttgtc tgctccctgc tgtccaagca ttgatcacaa aatattcgcc tcatcaagct
    20101 gctggacgga tcttcagtta taaccaatct ttccaagcaa ctggtaacgt agtagggcct
    20161 atgatcggct ccagtgtttc cagtgcattt ggttatcgcg gcgtctttct ttcgacttct
    20221 cttcttgttt tggtcaactt cttgcttgta cgacacaata cacaagagat ccatcagcaa
    20281 gaaactgcag aagaaaaagc ttcaggagtc tccatagctt cagggcactc tccttctcat
    20341 agacaataag cgtaaatgaa aaacactgct tgaacagttg tcacagactg tccttgcagt
    20401 gtttttgttt aggcctgttt tttcaagaac tcagataaga ggaataatcc cttttccaag
    20461 gtttcttttt tacaacagta acctagtcgg gcatgcttcg gtaaatcaaa ggcacttcct
    20521 ggtactaata gtactcctgt ttcttctaat aaattgatac aaaatgtctg gtcatcttct
    20581 tcgatggcta atttaatgaa agaagtagag acgtaattgg gagcgacaag ttcaactttc
    20641 ggttcattgg ctacccattg ttttaaaatc acaaggttct ctgtaatgat ctttttgttt
    20701 cgcgccaata ttttttcttt attcttcaat gcatgtacag caagatcatc tgacaggact
    20761 ccgccgcaaa tcatcgtgta gtctcgatac tttcgaaaaa cttctgccaa ctcaggtcca
    20821 gtagctgtcc agccaatacg aatacctgga atggagtagg ttttggatag ggaattggtt
    20881 gctatacctt tttcatagac atctacgatc gacaagaatt cacctttatc cgttaaaggc
    20941 gcatatactt catctatcaa tacatatgca tctactgtac gagcaatttc tgcgattttt
    21001 tctaaagttt tccgatctag caatgtgcct gtaggattgt ttgcactatt caaacagatg
    21061 atttttgttt caggtttgac taaggcttct agctgttcta aatcaaactg ccaatcttct
    21121 tcttccttca aatgaacaaa gtcaacagcg gcacctaaag atttggggat gtcatataat
    21181 tgctgataag taggaagcat cgaaacaaca tggtctcctg cttccactaa cgcgtataga
    21241 gctaaaagat tagcaccagt cgctccattc gtttgtaaga tgttttccgg atcgacggtt
    21301 tgataaagag aagcgacttc ttgtttgaaa acatctgatc cttcgatcca gccatagtcc
    21361 aatggttcgt ttttgcgttt ttcgaaaaat ttacttacgc tagtcccatc taagccaacg
    21421 agttcgtcta atgtcaatgc ttcgatcgag ctttgtgcaa tatcatatac cgctttcttt
    21481 tcccatttat ttagccattc ttctacaccg aaatttgcga ttttcatgtt tctttccccc
    21541 ttatatcttg atccagccta cagcaagcaa cccgattgaa agcagtgcgg ccacacaaat
    21601 cagcccaatc attacttttt cttttcccgt aatttgatgt ttggtttcac gacaagcgat
    21661 ccagtagaag caaaaaccag gaagataggc aatactacat aaaaggacat aagaaaatcc
    21721 tgctaaaatg atgcccatca attcaaaaac tacagcaatc ccaccgatca ctacttgttt
    21781 tttgattcct tcttttaaag aaaactggac ttgatagatc ccgacaagta gataacaaat
    21841 caaaattgcc gctgtacata aagaataggc aaattgatag gcataatcag taattaagaa
    21901 agtcaataag aatagattag tcaagattgc agtaacaact aacgaataag ttggggcatt
    21961 ttttttattc gtttttcccc aacctttcgg caacagaccg tctcgagcca tcaacatcgt
    22021 tgtttctgct gggagcatcg tccaagacaa ccaagaacca atgatcgaaa taatcaagcc
    22081 gatattgatc agcgctgctc cccaatttcc cacgattcct tttaaaatat ttgccatagc
    22141 aggttgtgaa atagttgcta actcttcttg agataagacg ccgtatggca agatcgaagc
    22201 aaggatatag ataaacaata aacaaagcag accaatgatc gatgcttgct gggcttctga
    22261 acgtttcttc gcgcggttgg ctaaaacact tgcgccttcg atccctacaa agacccacat
    22321 cataaccatc aaacaacctt taatctgcaa ccagatcgtt ccttgctgcc ctgttccatt
    22381 cactagatta tcagatacgt taccccaaaa atcagcagtg aatatattca ctttaaatgc
    22441 gataaataca aatattaaaa ataggaataa tggcactaat ttacagatcg tcacgattgt
    22501 attgatgacg ctcgctcctt caactccatt gtttactaat aaagtcagac cccaaataaa
    22561 aatacttgca aataaaatag aaggaacatt ttgtccacct ttgaatatcg ggaaaaattc
    22621 tcccatggcg ctcatcagca tcgttgcaaa agcaacattt cccagccacg cagacaacca
    22681 gtaaccccaa ccactgatga agccacctaa tttaccaaat gaagcttccg cgtaaccgaa
    22741 aataccacca tctagatctg gacgcttttc tcctaaatga ttcagcgata ataccaaagc
    22801 taaaatacca atcccaacga ttatccatga aaggatcgct ggccctggag ctgcagaact
    22861 agccagatca cttgtgatcc caaacacacc gcttccgatt gacgaactga caaccagagc
    22921 aaccagtccc catttgctaa tacccgtcga tttcttttcc atttccatca ccctcactta
    22981 taaaattgaa caaatcactt gcaaaagatt cccttctatt ttgcaactgc tcttgcttaa
    23041 caaaaagcaa ctttattcat attattggat attatgaact ttttacacaa gtatttcaag
    23101 tataaaatga ataaaaatta attttattgc aaaaaaacag ctatgctatc caaaagaaaa
    23161 ggtgtttctt ttgttagcca tagctgtttt gattcattta atatcgctta aacgtattgt
    23221 aaaacttttg tttcttgata tgcgtggtcg atcaaaccac cacccagaca ttccattcca
    23281 tcataaaata caactgcttg tccaggagtg attgcacgta caggttcgtc gaatacgact
    23341 tctgcacgat tatcatccaa taagcgaact gtcacaggaa cgtcttgctg acgataacgg
    23401 aatttcgctg tacacttgaa ttcttttggc attggttcat tcgtcgtaaa gtggatttca
    23461 cttgcatcca agcttgtggc atacaatgca ggatgatgga acccttgccc cacatataat
    23521 gtgtttgtcg ctagatcttt tcctacaaca aaccagggtt cttgcgaatc tcctccgcca
    23581 ccgatcccta gtccttgacg ttgaccaatc gtataataca tcaagccagc atgttgtcct
    23641 ttgacttcac catcaagagt gaccatattt cctttttttg ctggcagata gttgctcaaa
    23701 aattgtttga agttcttttc accaataaag cagattcccg ttgaatcttt tttcttagca
    23761 gtcgcaaggc ctgcgcgttc agcaattgcc cgtacttctg atttttccat gccgcctaga
    23821 gggaacatcg tttttgaaag ctgttcttgt gataattggc taaggaagta agtttgatct
    23881 ttattattgt ctactccacg aagcatgtgg accacgccgt tttcatcgcg agtgacttgc
    23941 gcataatgtc cagtagctac ataatcggcg ccaagatcca ttgcataatc caagaatgct
    24001 ttgaatttga tttctttgtt gcacatcacg tctgggttag gtgtacgtcc tgcgcggtat
    24061 tcggctagga aatattcaaa tacacgatcc caatattctt tttcaaaatt cacagagtaa
    24121 taaggaatcc cgatttgagc agctactttc gctacatcct tataatcttc cgtggccgtg
    24181 catacaccgt tttcgtccgt gtcatcccaa tttttcatga atattccgat cacgtcgtat
    24241 ccttgttcct ttaacaaaag tgctgttaca gatgagtcga caccgccgct catccctacg
    24301 acaacgcgtg ttttgctgtt gtctgtcatg atatcaccat catttcaatt agattctgaa
    24361 acatctacga gttgaaggtc gcaacttttc agtattttac attatacgtc atatttctga
    24421 aaatttcatc ccttaattat caagtcgtaa aaatactgtt ctactggacc tattcagtac
    24481 acaaacatga tagtcaacca aaaaatcact catcttttga gcattcgata taaaaaattg
    24541 gcatactcat aaaaagggcc agcctttcgg caataaggaa taattttata aattgtgaaa
    24601 aactattttt caaaattgct tcttatcgct taaagctgca cgtctcattt acaacctttt
    24661 ctttttagat gttatgagtt gctcagataa gtgattttgt ttactctaag aaaaaaggga
    24721 ggcaaaagat acatgaatta ctttatcagt gatatgcact ttttccatga acgcttatta
    24781 ggaaaaaacg actttgctcc gcggctcttt gcaaatgtgg atgaaatgaa ccaacagttg
    24841 atcactagct ggaatgcagt aataaaagaa accgaccatg tttatcatct aggcgacctt
    24901 gctatgcatc cgcaatatga aaaagcaaat gcagaaattt tggaactggt cactcaactg
    24961 caaggaacaa tccacttgat caaagggaac catgacagtc gcgctttttt ccgttattta
    25021 gaaaaaaatg atcctaggct tactgacgga agtcccaaat tttattttta tgatgtaggt
    25081 gccatcgtta aattcgacca tcaacaatat tacttgactc attatccgat gttgctcggg
    25141 cctaacgaca ctatccgcaa tcttcatgga catatccatc attacagcgt acctatcgag
    25201 aacgatgtca atgtaggcgt agacgcaccg gaaagagaac tcttaaagga aaaactacca
    25261 tttggcactc cgttatctga gcaacaaatc aaagaaatct atgaagcaaa gaggaagtac
    25321 gataggtcgt gaaaaaactg ccctatatca agtattaaac aaataaagat aattactcat
    25381 atttttcatt tgagtaggct tattgccaca ggaacattag gatcagaaat ggagttgtaa
    25441 caagacttct gtcacaactc cattccatac tattcgtctt tttgctcatg gtgttctttt
    25501 accagttttt tctgtaattc tttatcataa tttcgggcag ctgacgttaa aaataaaacg
    25561 attccgcata ataaaatccc gattccggaa aacaagaaca ttttttctac ccctaaacga
    25621 tcagctaatg gtcctgcaaa taataatcca attggacctg ccaggttcat caaagagttg
    25681 aagttcccta agacacgacc taaaacattc gattcataac tctgctggat cattgccatc
    25741 agcagtgtat tgaaatatgg cgttgcacaa cctgctcctg cattcaagat aagaaagtac
    25801 aagaaccctt gactatcgtt tggaaccaat ccgcttgcac cgatcgtcag gcccataatg
    25861 atgtaggcta taataatagg tttcattcgg tctttccatg ttcctataaa actgatcagt
    25921 gcaccgccta agagcattcc gactgcgtag actacttcca ctgctcccgc ctgtccaacg
    25981 gaaccaccaa agtaatctag cgtcatcaat ggatacagac tgattgctgg catgaacaac
    26041 agcatcacaa atgcaccatt gatcgttatg taccataacc ctttattatc catcaattgc
    26101 tgcagcccaa attttgcatc tttaaaaata gtaagcggaa cttccaatat ttcaggagaa
    26161 acttttggga tcttcacaaa aatcaataag ccgacaccaa aaactgcccc caatacatct
    26221 aataaaataa ggtaattgac aggaacgact gaaaacaaag ccgcacctag agctggcgca
    26281 atgatgaaat tcgctgattg gaccattcct aactgtccat tcgtccttgt tatgtgagaa
    26341 gatggaacga ttgtcggcat aatcgactgg atcgttggca tttggaatgt ttgtgcgacc
    26401 gaacgcataa acaaagacac aaaaactagc caaatcggga aggattctga aatcgttccg
    26461 actactgcta aaataagcgc gaaaatcgct acaataatat ccgtgacaat caaaagagct
    26521 tttttatccc agcgatccac tagcggtcct acaaatgggc ttagtaaaac catgggaatc
    26581 attcctagta aagtagcaaa actcaaaatt gtcgccgaac cggtttctct tgtcaaatac
    26641 cagatgatcg catattggac gaccatacta gtgattcctg acaaaaactg tcccgataaa
    26701 aagaacaaat aatttctctt ccaattcgtt aaaacgaccg actgttcatt ttccataaac
    26761 atccctcttt tctttttcat tttgtatagc gtttgcacaa caatcattat acgggattct
    26821 tttttcaaaa aatacctttt tccctaaata acaatcgttt caatttaaat ttctttactt
    26881 agaaacaata aatcagcaaa atattaaaaa taacaacatg tgttaaattt aaaaataaaa
    26941 aagacaacta atttgcgtcg tccttacaaa gttagtcatc taacaatagg ccgtttcaaa
    27001 actagttgtc tttttatatc cacagatcat tcgacttttt cgaataaccc acggctaatc
    27061 atcccatcca tcagaaaata aaatttatct tggctcattt tctgttttgg atctttgaaa
    27121 atattgactg ctttcaatcc atttgctgta gtgatcgaca ttttcaatgt ttgaatatct
    27181 tttgatacag tgatttttaa tttgaatcct tctttgcttt gcggcgtggc atctaatggt
    27241 cggatcaatt gataattgcc tccgtttgtt tctgtaaatc cattatcgcg caatgtatat
    27301 ctttttgcat caggatgcaa acgatagcta attggtgcgc ccagtaccgt tgctgttgtt
    27361 tcaaatgcca tgattttcac ctcgataaaa ttagtttctc tttattataa aagtttatcc
    27421 tgatttttac taggtttttc agttaagttc cctaaaaaat gaaggcgttc tctcagacat
    27481 ctgttcatat aagaatgact tcactagtta ttttttgaca gcacgaacta attgatcaag
    27541 gaaatactgg atgtcgtctt cggtatttcc caaaccaaag ctgatacgga tggattcttt
    27601 tagtatcggt gtatcttctc catacattgc ttctaatacg tgtgaaggct cgatatttcc
    27661 tgctgtacaa gctgaaccag tagaaatagc gaccccatta agatcaagct tcatcagtag
    27721 caaatcattt gcttcgccaa ttaagcgaag attcaacaca tgagggagtt tattcgttaa
    27781 atcaccattt acttgataag ggatttcgtt tgcttctaat gtatcaagaa tcaattgctg
    27841 gaatccttta tatttgttgt tacgtgcttc acgttcttca ggtgacagca gttcaactgc
    27901 ttttgccata ccccagatcc ctgctaaatt ttctgtacct gcacgccgct tttcttcctg
    27961 ctccccgcct aaaagcaatg cagggatatt tactccgtct cgtttatata agaaaccgac
    28021 gccttttggc ccattgattt tatgagcaga gatacttaat aaatcgattc ctaattcttc
    28081 tggatggatc gtttggtttc cgtacgcttg taccgcatct gtatggaaat aagctggatg
    28141 atccgctaaa agttcaccga tttctttgat tggcatcaaa tttccgattt cattgttccc
    28201 gtacatcaca gagaccaaga tcgtatcttc tcgtaacgct tttttgacct cttcgatcga
    28261 cagattccct ttttcatcta caggcagata tgtaacgtca aacccctttg tctctaaata
    28321 tttcatggta ttaagaacag caggatgttc gatagctgta gtgattagat gtctgccttc
    28381 tttttgacgc gaaaacgctg tttctaagat agctgtatta tccccttctg ttcccccact
    28441 gttaaagatg atctcgtgag gttttgcttg cagactgtct gcaatgattt gtcttgctgt
    28501 ttccaatttt tcatgcgcgt ggcgaccaaa tccatgtatg cttgaaggat ttccaaacgt
    28561 gtcttgcatg attgccgtca tcgcttcaat tacttgtgga tgcatggggg tagttgccgc
    28621 atgatccaga taaatagttt tcacttcatt catcccttcc aaattattgc taggcacatt
    28681 ctagcataaa atagcgaaca aaccaaagaa gagctcattt ttgtctagag gacgtttcat
    28741 gggcatagaa aaaaggagct gtgacaaaag tcttgtcgca gctccttgaa gctgctcact
    28801 tctgtcacaa cttctttccc tctttttttt gtttattcga attctttttc ttccagacgg
    28861 aataacggac tcatcggtgt attttcatgg atgcgtttga ccgcttcacc cattaattct
    28921 gaacatgtaa cgattgttaa gttttctgga tgacgatttt cttctgtgaa aacagaatca
    28981 gtgatacaaa tatctttgat tggtgcattg tctaaaatac ttttcgcatg atcggacaat
    29041 aatccatgtg acgcacaggc atatacttct tttgcgccgt tttcttttaa tacatttgct
    29101 gctcgtgcaa gcgttgctcc tgtgttcaag atatcatcta ccatgataca tgtctttcct
    29161 tgaacatcac cgatcacata accaccctca gttgaagcat catctgcatg atctacgatg
    29221 gctaatgtgc tgttcaaata ttctgaaaga ctacgtgcac gctgaacacc gctgtttttt
    29281 ggcgaaacaa ctacgatgtc atctcccgtc agacctaatt gacggtaata atgagcaaac
    29341 aacggcatcg taaataaatt atctacagga atatcaaaga atccttgtac ttgaaccgtg
    29401 tgcagatcta aagtcagtac tcgagttgcc cctgcttctt cgatcaagtt agcgatcaat
    29461 ttcgcagtga tcggttcatg aggtttcgcc gtgcggtctt gcctagcata cccatagtaa
    29521 ggcaatacga cattgatcgt tttcgcactt gctcgcttca ttgcatcgat catgatcagt
    29581 agttccatat agtaatcatt gacaggtgca ttcgttgatt gaacgatata cacatgatcc
    29641 cctcgaatac tttcttcgat attgatggaa atctcgccat cactaaattg cttcacgacg
    29701 cttttaccta attctgttcc gaacactttc gcgatttttt cagctaatgg acggttgcca
    29761 ttcaaactaa aaatcttcaa cgtgtcatcc tgatacttat tactcatgta gtcctcccca
    29821 aaacttctct attcttcgat agtttaacat atttttccaa gattttctgt taatttcagc
    29881 aaattcttaa ggaagtgaaa ctgttccgtt actccaactg gcaggaatga ctttatgata
    29941 atcgccccag ttgtcgtgta ctttgtaata acgttctcct gtttcagttt caaaataagc
    30001 gtacgctgtc acccaatgat tgccatatgt actgccaagt actttcaaaa taccaatcat
    30061 cacaggtttg ccttcacgta tacgttttgt agctcgctgc catgaaccta gaagagttgc
    30121 tcgtgcacgc tcatgattgc cattcttctt taaaaaacta gaaatccctg tactaacctg
    30181 aaaaggaatc gtaggaagtc ctagtggttg gatctggcta cgcaatgcct tcgtcaaaac
    30241 caacgaatca gccgtatttt tcttgcgaat ctcatttgga agcatccacc ccttacgata
    30301 gtcttgataa taggcaagga gaactgctgc cgcgtaagta ccacaaagat agcctgaggg
    30361 ggtagcccat ttcttatacc tcaaaaaacg ttcttctggc aatcccaccc agcaatttgc
    30421 gagttccttt cctgaccttt tttcttcgat caaaacggga atatcttctt ttctgttgat
    30481 ccatctagat aactcgattg gctcttcatt gatcagcttc cattttttac aagaaagacc
    30541 ctcttgataa gtatattttg ctggagaata ttctaccgga tgtcctgatt gatcgataat
    30601 cacataactt tgatcttcaa aaaccagagc taaaaaaagc aatttacttt ttcttgactg
    30661 cagctgctga gtgctggcta attttttaat ttttttatct actttgaaat ataaaggttt
    30721 atccactact tgattcagtt gggatcgcct cctttttttc attataagtg aaggattgaa
    30781 aaaaacaaat cagtttgatt gttcgaattt tcaatttttt atgttctatt tgttaattcc
    30841 ttcattttgt aagataatgg gcacacgaaa caaaaaagga gcgatcgatg aatgaacaaa
    30901 gaacgattga aacaagattt ctatgaagca gtcaatgaag aatggcaaaa aacagcaaaa
    30961 atccctgcag ataaaccagc tacaggcggt ttccaagatt tagttgacgg gatcgaccaa
    31021 cttttgatgg gagaaacaga cgatctgctt gcccatccag aaaaagtgtc ttcagaaaaa
    31081 atgaaacatt tccttgcata ttatcaactg gcaaacgatt atgaccgaag aaatgagttg
    31141 catgctcaac cgcttcaacc tataatcgaa aaagttgaat cattgcagtc tttcgacgaa
    31201 ttgaataagc aatttccaga atggctgttg gatacattac cattgccatt taatctggat
    31261 gtagatgcag atatgaagaa tgcgcaaacg aacgccttct ttgcttatcc gccttcttta
    31321 ttccttccag ataagacgta ttatgcatca gaccatccca acggtgcaca actaataggc
    31381 gttttctttg atatggctgt tcagttatta gagcttgccg gcaaagaaaa aagtcaggca
    31441 gaagcaatca cggaacaagc agtgcaattt gataaattga ttgctcctca tgtaaaaagt
    31501 gcagaagaaa acgcagatta cagcaaaatg tataatccgc aatcttttga tacatttatt
    31561 aaatacacag ataaactgga cttgaaaaaa cttgtcacgg gtttgattgg gacaactcca
    31621 gataaagtga tcgtaactga tccagtgtac ttcgatcatt tgaatgacat cctgacagaa
    31681 gctcattttc cgttattcaa aagctggatg atcattaaaa cagtacgttc tcttagtggt
    31741 tatctatcag aagaattccg ccaagtcagc ggaatctatt ctcgcgtatt gtctggaaca
    31801 gacgaagcaa tgcctcagaa aaaagcagcg tattaccttg cctctggaca attcgatcaa
    31861 gtagttggcg attactacgg aaaaaaatat tttggcgaag ctgctaaaaa agacgtagaa
    31921 caaatggtga aaaaaatgat cgccgtttat aaaaaacgtc tagaagaaaa tgactggctt
    31981 ggggatgcaa caaaagaaaa agccgtcata aaattaaata acttaggtat ccaagtaggc
    32041 taccccgata agatcccagc attattcgac cagttcaaaa cagtacctgc agatcagggt
    32101 ggtactttgc tttcaaatac tcttgttttc agcaaactca cattaaaaga tcgtttcagc
    32161 aaatggaaca aaccagtgga tcgttcagaa tgggaaatga gtgctgacac ggtcaatgct
    32221 tattatcatc catttcggaa tgtgatcgtc tttccggcag cgatccttca agcaccattt
    32281 tacagtctag aacaatcaag ctctgctaat tatggtggaa tcggagctgt tatcgctcat
    32341 gagatttccc atgcatttga taataacggc gctttatttg acgaatatgg caacttgaac
    32401 aactggtgga cagaagaaga tcttacacaa tttcaaaaca aagcacaagc aatgatcgaa
    32461 gaattcgatg gtctgccttt tgctgacgga aaagtaaacg gaaaattaac cgtttcggaa
    32521 aatattgctg atgcaggcgg tctaagctgt gcattggaag cagcaaaaac ggaatcagat
    32581 ctttctatcg aggaattctt tgtcaattgg gcaacgattt ggcgtacaaa agcaaaaaaa
    32641 gaataccaac aacttttact gcaaatcgat gtccatgccc ctgctaaact ccgagcaaac
    32701 gtgcaaccaa aaaaccttga cgaattctat gaaacatttg gtatcacgga acaagacgct
    32761 atgtatctag cgccagaaaa aagagtgcga atctggtaag aggttgtgcc agaagtggtc
    32821 agcttcaaga aataagaagg aatttgggaa aatcgcttct caaatttttg tgacatttcg
    32881 gcttattttt cgaagaagtt acttctggaa taccatgtat tagaggttgt gaaaaagctg
    32941 cttagtttca agtagtaaga aaaattttgt gaaaatggct ttccacattt ttgcataaat
    33001 ttgacttact accgagaaac tggcttttga acaccgttta tcgagaggtt gtgaaatcag
    33061 cgtcctgacc tgagtattag agaaaaaaac ggaaaaatag ttcctcatat tttgccgttt
    33121 gttgagctaa taccgagggt cagctgattg aacaccgttt agtggagaga ttgtgaaaaa
    33181 gctgtcctgc atcaagtaat aagaacagcc aatcaaaagc agcaaggaga acctcatcta
    33241 taaaaagata gaaggaagtg agacatctat tggtctcatt tccttctatt tttactttcc
    33301 tcagtcaatt gttttacatc ataaaaggag aaattccact tatttttttc gctgtttcat
    33361 gacataaaca actacaccga ttaacaaaat tcctccagct aatgctagca acgggttatt
    33421 aaattctccc gtttttggga gtccttgagt gccatttttt tcactttctt ttgctgtcct
    33481 atccggatga gaaggttttc catttggttt tccatttggt gattcatttc ctggattttc
    33541 tctttctggt ttgtcatttc ccgggggcac atcggcagtt tctcgcacag tgatcgcttt
    33601 ttgctgggta acagattctg tatgagcaga ccatttttcc ccatcaaata tttccgaacg
    33661 ataagtgact tctagcgtat attctccttt tgaaggtgct gaaaaaatag cggtatgatt
    33721 agaaaattga gcacttgact gtgtttcaac gatttggatc ttttctggga aataacgcat
    33781 atcttcaaag acaggcgttc cttgatttgg tgtgaaagtt gacacaaaaa ctgtaaaagg
    33841 cttcagttca atgatatttc cttctgcatt ctccgccaca ccatttgctt cttgtataat
    33901 aatcggatta ttttgttcat ttggttttgt ctgatttggt tcttgtacga ttgcatactc
    33961 tggatattcc gaagacggtg aggtttctcc gtcaaaaata gcacctacag ataatggaag
    34021 accatccact ctttcctttt ctgtttgacg attccccggt ttaatctgca tcagtccatg
    34081 aacatggata cttccatttt catagcgcgt aacaggctgc tgaccttctt tcgaacatgt
    34141 atttagagac tcgatccaat cttttgatat ggtatgtcca agagtatttt ctgattgttt
    34201 ctctcgttca ttccaatagt agttcaacga gtggtagatt tgatcttcgt tttgattcaa
    34261 tgggcggatc tgctctctca tctcaagatt ctctgttcgg aaagataaga taccagaagc
    34321 atggtagtct gtgtttcctg ctgaagaggt ataaagagcc acattatatg aaccgttatt
    34381 aaaacttgta ctgctattga cgataatatc tgttccgcta ttggaatcga ttcctttcgc
    34441 aagattttcg aaagacaaac tattgatcaa ttcatgaggg cccgttaaag aagaaccgcc
    34501 cattttgaat ccattaccgt taccttctcc ctcaattcct ggtacccagc cgtttcgata
    34561 agcaactgag tttttgatga ttacttttcc gatcgaacct gtttcatttt tagcaaaaag
    34621 gtcccaaccg tcatctgcat tatgatacgc gatacaaccg tcaaatacat ttccttctcc
    34681 tattgtcagt ttggccgcaa atccatcggc atcttcaaat cctggatcgg cattttcaaa
    34741 agatgtacag ttcttgacta agttatgcgc gggccatgct tcgaaaggat catttgagct
    34801 accgctgatt tggattcctg tatttccatt ccgataagca tgaatctctt cgatcaaatt
    34861 atgatttcca gaaatctgta atcctttttg catagctgca ctatttgtaa tgtcaaaccc
    34921 tcgtaaaccc cagtagtgac tgaacagtgt catcccattt ccagttcctt taaaatcaag
    34981 tacaggacgc ttgttttctg gatttttctc tgcaatcaac tgaatcgggt tttctcttgt
    35041 cccgttaacg ccttttggaa tcgtcaatcc tctttcgaag gaataagttc caggcgccat
    35101 gacgattgtc tgcccagcat atgcgtatct caatgcttgt gtcagagata atggattttg
    35161 tctgcttccg tttcctgcat ctgacccttc tggtgttaca taaactgtcg aatatttagg
    35221 tttacggtag tccactgtat gaagaatctc ttttgtttca taactagtca tctctacgta
    35281 ttcttctggc ggatagtttt tatctggcgt aaaactgaaa gtaaattcgt tcgttccttc
    35341 catcagtttt gtctgataat caaattcccg attcgcagtg atagccaagt tttttgcgtt
    35401 cttaagcacc tctcctgttg ctttattttt aattgtcaat aatccgtcag catttgctct
    35461 aaaggacata gtatgatctt ggtttcctga atgattacta gaggtcacag tgtaaatcgg
    35521 atcaatcaag cgagtaggtc tttcttgccc aggaggatct gtcgcaggat ctgagtaagc
    35581 aacttcgatt ccttctacct tgatcgtcat attccttgct gcagcaaatc ctgcataaat
    35641 aaccgattca tctgaagcgt ataatttttc ccagtcatac atgatgtcag aagccatttc
    35701 ttctcctgtt tcaggatcgt aataatatgc ctctaaacca gtattcgttt ttttcatctc
    35761 tacgtccagt ttagtaatcg agttcgtggc cggaaacaga ttcccatgac cgtttccgaa
    35821 tatattataa gaacctgttt ctttttccaa gaaccctgct gaagtctcta aaggtgttgt
    35881 ttccactgag acactcccag gagctggcgc agcttgcgga tcttcagatg atattcctgt
    35941 gattgcccgt gtccccaatc caagtcgcat cgtatatttg ctgccgctcg tgttgaccac
    36001 ttcttgtcta tccgagtccc agacatattc gatccgactg cctagtatgg caaatgaatt
    36061 tgaataaaat gcctgcccaa acaaatgatt ttttggtact gcgtctctta ccattaaagc
    36121 aaatccttct tgggcattcg tataggtcca agattctatt tcgatcgtcg cccgcatcct
    36181 aaagttgatg tctttgggga ttgcttgata ataataggtc attccatctg atccgcttga
    36241 ctggaatttt ccgccgttat tcgtggaaga gagccgcacg ccgtcttcta atggttcaat
    36301 ggcataccta ctagcacttg tgctttctcc gaaaacaacc cctttccact cttcatttgc
    36361 ttcttcagat tgcttttttg tcttttcatt ttctgattct ttcatcatag gatcatttcc
    36421 ttcttccgta tccatatctt cactagttct tggtatttcc tccattgttg acatcccttc
    36481 aatgttcacg tgtgcatttt cttcgttcac agactgttgt tcgttagcag caacttcaac
    36541 gacagaaatt aaaaccgggg tactgagcat aaggagattc atcattagcg cactgtattt
    36601 tatacgtttt tttaacaagt gtattcctcc cgtaacaaat tagaaagcgt ttacttaaag
    36661 tattacctaa tttattttta ctgtcaataa aaaacaaaat tataataagt gtattttata
    36721 aaaagaaaaa atataactta agttgttgat aataaagaga tttattaacg gaaaaagaat
    36781 aagttttttt aaaataacgt ataaaaaaga gcataaaaca aagtcgtttg ttttatgctc
    36841 ttcttttatt attttgtgct ttttatttta tcaaatcact ttgttttttt ataaaatttc
    36901 tgcgcctagt gtggactcaa aatgtctcaa tgcccattca tgtccaacgg gatcgaaact
    36961 tgccacggaa tctttgaaaa tatggagttt gtatcctaga ttatacgcat cgactgctgt
    37021 atgcaacaca cagatatctg tacatacgcc ggtcaaataa atatctgtga tctggcgttc
    37081 tcgcaaacgg atgtctagat ctgttccact aaaagcggaa taatgccgtt tgtctatcca
    37141 ataaacattt tcctcttgct catagtcttg gtataaactt tttaaagagc cgtacaattc
    37201 ccgtccaccc gttcctatca cattatgcgg aggaaataag cggttctccg gatgaaagga
    37261 atcttttgga tcatgcgcat caatggcaaa aacgacaaaa tccttttgat caataaactt
    37321 ctttgtatga gcagtcagct ttttttcaat tacttgtcct gctgtcccag tagtcagctt
    37381 tccatcctct gcaacaaaat catatgtgta gtcaatcgag atcaatgcgt tcatcttagt
    37441 cctccttata cgagatgttt gacaaattcg atcaccattt ctgctgatcg tttgcctgcg
    37501 tcttcgataa attcgtcaaa gctttgtgtc gccgagtgat ctgctgtgtc gctcattgca
    37561 cgtacgatca aaaatgggat attgaactga cgagctgttt gtccaacagc ggctccttcc
    37621 atttcgcaag ctaatgcttc agggaaattc gttaagattt ctttgatttt atctggcgag
    37681 tcgacaaatg tatcacctgt aacgatcaat ccttcttttg cgttcaaatt cgttgctttt
    37741 gctgctttaa ccatttcact gcgcaaatat gtgcttgctt cataatatag aggcattcct
    37801 ggtaattgtc ctgggttgta gccaaatcct gttgcatctg catcaaaata agctactttg
    37861 tctgatataa cgatgtcacc tacttgtaag ccttcaccga ttccgccagc tgaacctgta
    37921 ttgatcacca tgttcacgcc gtattgttgg atcaacagac ttgtggtaat agatgctaag
    37981 acttttccta taccggaacg tacgacgatc acttcgtggt tacctaatga acctgaaata
    38041 aataaagcgc ctgcgcgttc ccatgataat ggttcgctta ggttctctct caaaattttt
    38101 acttcttctt ccattgcgcc gataataccg attttcatct ttttaattcc ttctttctat
    38161 ataaatgcga ttgctaaaaa aaccacacat aacattagga taacaataat aagagatttc
    38221 atcaaaaaag agttccattt ggtcgtcttt tcccgttcgc tgatccttgt tttcgtgatt
    38281 ggtttattct ttttgctttc tttacgataa aagctggcaa tctttttttc ttcttgctga
    38341 taagctgttt ctgcttttcg ctgttttttt aatgactcgc ttgcttgtgc ttgttgtcgc
    38401 ttgcgaagtt cgcttcgcgt aataagcggt cctttggcca taagccgatc cctctacttt
    38461 cctttggtca atagttccca gtattgaatc gcataaatcg tctttgcatc acaaatcaac
    38521 tgatctttca tcgcttgttg cgcctcttca agagttagat gatacaactc cagtacttcg
    38581 tcttcatctt gtgctaaagg attctcgacc ttctctaccc cttgtgcatg ataaatatga
    38641 aggacttcat ttgcaaaacc tggtgaaaga tacatcgaag taagatggct cagcgacttc
    38701 gcacgatagc cagtttcttc ttctaattct ctagctgctg tcatttcggg attttgtcct
    38761 tctcctggat cgatttttcc agctggaatc tccaaaatca ctttttctaa aggttttcga
    38821 aattgtttga caagaagcag acgatcttgt tcgtcaaaag caatgatccc gacaccgcca
    38881 ggatgaaata ccagttctct cttcgaagtt cctccatctg gcaaacgaac ttcgtctaca
    38941 gcaacatcaa taatttttcc gctatagatt tctttgcgac tgattgtttt ttcttcaaat
    39001 tgctcattgt tcagcatatc ttctcctgct ttctttgtaa tcataactgc ttttttttca
    39061 tttttcaatt tttctcaaaa actccttatt agtttaccat agataaacct tagattttct
    39121 ctaaatatag aaaatccttc tttagtccga tactctttct agtagtccgt atgctaaaat
    39181 aagtatgtaa tcgaataacg aaaagaattc aatactcaac gataaatgac atggagggtt
    39241 tattatgata aaacgaaatt ggccgtggct tctagcattg gtcttgctat ttctctttgt
    39301 ccgaaacaat agtttttctt ttgttctagg acttttattg ataggtgtag ttttagtttt
    39361 gtggggactc tttggttcgc gcaggaaaaa gggaaaacaa gaagaaattc ctgcactgac
    39421 tgacgaactt gaaactcact atgaaaaaag cggtatgaca gcgaatgaaa tttcattttt
    39481 tcgacaaaca atgaatcaaa caaaaaatga gatcaatcaa ttgcaaatga atatgcagca
    39541 gacagccaaa cttaaagcaa tcgatctccg ccatgatcca gtcaaagcag cgaaagcttt
    39601 attcaaagaa ttggtgaaag aaccaaaccg actgcatgaa gcaagtcagt ttctttatac
    39661 gcatctgccg aatctagttg atttgacaaa taagtataat gagatcaatg accatgagat
    39721 caaaaacaaa cagacctatg aaaaactaga agaaagcgcg cagatcatcg accagctgtc
    39781 agctttaatc gcacaagatt atcaaaaatt cgttgctgag gatctagatg atatcgacgt
    39841 agagatatct gttgcgaaac agagcttaaa gcgtgataat aaatatgaac cagaacaaaa
    39901 ggattaactc ttttgttcat aaaagaagac tcggaacatt cagatgatgt ctggctgttt
    39961 cgagtacttt ttctaaagta gagacattca tgtaagaatc gagaacagat tcaacaagga
    40021 ggaatttttt atggatcata aaccgactga aacaaaagat gttacaccag ttaacgatac
    40081 acttgaagat ttattgaaca acccgttttc aactccaaca gatacgctga ccacttcaca
    40141 acaagcggag attgatcagc tccaagagca acagacagct gctcgtttaa ttgacaaact
    40201 accggcggaa cgccaagaac aagctaaaca gctagcagca aaaatcgatg ctaatgatgc
    40261 acagtctgtc atcagctacg gatcggctgc ccaagcaaaa ttaagtgaat tctcacaatc
    40321 gatgttgaat catgtgcaag cacaagatat tggtcctgta ggagattcct taactgaact
    40381 gatgtatcgt ctccaagaag ccaatcctga cgaactgcgt gccggagaag ggaacatctt
    40441 ccagcgtgtc ttcgggaagg tcaaacaatc gatctatgaa gtgacagcaa aatatcaaaa
    40501 gattggtgca caaattgaca agatttcagt gaaattagat aaagaaaaag acggtctgct
    40561 aaaagataat ctgatgttag aacagcttta ccagaaaaac aaagactact ttgatgcact
    40621 gaatatttat atcgctgctg gagaattgaa aatggaagaa cttcaaacaa cgatcattcc
    40681 agaagcgatg aaaagagcag aagaaactgg cgatcagatg gatgttcaga ttgccaatga
    40741 ttacacgcaa ttcctagatc gtctggataa acgtacgcat gatcttcgct tagctagaca
    40801 gatcacgatc cagcaagcac cacaaatccg tttgatccaa aacacaaatc aggccttggc
    40861 tgaaaagatc caagcatcta tcgctacagc cattccgctg tggaaaaacc aagtcgtgat
    40921 cgcattgacc ttgcttcgtc aaaaagatgc agtaactgct caacgccaag tctctgaaac
    40981 aacaaacgac ttattgaaga aaaattcaga aatgctgaaa atctcagcca tcgaaacagc
    41041 gaaagaaaat gaacgtggaa tcgtggatat cgagaccctt caaaccactc aaaatgattt
    41101 gatcgaaaca atccaagaga cattgcgtat ccaaaaagaa ggaaaagaaa aacgtcgtca
    41161 tgcagaagta gagcttggac acatggaaga agatctgaaa caaaaactgt tggatttaac
    41221 ccaatagatc acctttcgct tgttactaaa acaaacgccc aacaacagtt tattacaact
    41281 gttgatgggc gtttttctta tctttcttct aacttctcca ttggagtcta tttctcattc
    41341 atcttgctgt gtccatagcc atagccaaaa taaatgatca gtccaataac cattacgata
    41401 ccgaacacga tccatgtcac agtttgcaga cgaagcatca atacaataca agtcaagatg
    41461 gagacgattg gcaatagcgg aacgaatggc actttgaatt ctccagcttt tggtttgcca
    41521 aacatttttc tcaacttcag taagcctaga ctaacaagca tcaaataggc gagcgccatg
    41581 atattcgtta gttccgctaa tacattcaat gggaaaaatc cggcaaagaa tacagctgcc
    41641 acaccagcgg cataagtcgc ttttttcggt gtacgatgct tttgatcgat ttctgtcata
    41701 aacttaggaa gtaagccatc cttgctgaca gcaaacagta aacgagcaag tgaatacatc
    41761 atcgagatcg ttaccgtcag tagcgttaaa attgccccta cagcgatcac cgcgcccact
    41821 gttccatgtc ctacatacct cattgcaaaa gccactgggt cattgactcc tagttcagta
    41881 tacggaacga ttcctgtcaa gatcagcgtc acgatgatgt aaaggacagt agcaatcagt
    41941 atcgaaccaa tgattcctct tggcacatct ttttgcgggt ttttgacttc ctcggctgcc
    42001 attgcaacgg catcaaatcc caagaaagca aaaaacacaa gagctgcacc atctagcaca
    42061 ccggaaaaac caaaaggcat gaatggctgc cagttatcag gtttaacgaa aaatattcct
    42121 acaatgataa acaacgcgat gataccaaat ttgacatata ccatggcatt attcaaacgt
    42181 aatgctttct tggcttcaag cgacacgatg taagtgacga atatcactac gagcaccgca
    42241 atcaagtcaa tgtatgtacc attttccgga ttgtacccgc cagttaatgc ttgtggaagt
    42301 tcggccccta aacttttcaa aaaaccttgc atatagccag accatccgga agcaacagag
    42361 gaaaccgcta gtaaaaattc cccgatcaac aaccaccctg tcagccaggc agcaaattca
    42421 ccaaatacaa catacagata ggcatatggc ccaccaatca ctggcactcg cgaagcaaat
    42481 tctgcgaaac ttagtccaga caaaatgaca acgattgcag ctaagacaaa tgaaagtgac
    42541 agtgctggac cagcattttg attggccgca acccctgtca ccacaaatat tcccgtaccg
    42601 atgatcgcac caattccaag catgatcaaa tcagacgttt ttagttcttt tttcatctca
    42661 ctcgtatgat tgagattgat ctctttctta cgaaacaaat ccattgaagt tcctccccat
    42721 tttaggttgg aaaacagcga ttaaactgtt ttcatatacc ctaaaaggat accacctaaa
    42781 atgactaaaa ggcaaccaac aataacataa atgagctctt ttttcgtttt tctttcgcca
    42841 aggatgaaaa tcccacctaa agtagagata atgatcccca tttgtgaaag tgagaagcca
    42901 acagctaaac caagtgattt gactgttaga agcatgcaga tgtttcctaa gccccataat
    42961 aatccacaga tcatgttttt ccacacaaac tgatcgactt taactttacg gaaagcaaag
    43021 aagcttgcgc ctaagatcat tccgatactt tgaggtaaga taattgacat cgcatccaaa
    43081 ttcgcccagt tgacgatgat ggtatataca ccataaccaa tcgtagagaa gatcaatgct
    43141 ctaaaaccct taccaaaatc aagcatttta ttatctgtat ctatttttcc ttcgtcatct
    43201 tgtcgggcag tcaaatacgc accgcttaca agaagagcta aagcaataat accgtataca
    43261 taatctttcg tttgtgtcca ttcatggaag aaaacggctc ccgcaatcgt attcaaaatt
    43321 aattgaaaac cagtagacaa tggtagccct acagaaacac ccatgtactt cattccatgg
    43381 aactgtccat tttgtccaac actccaagct aagccggata aaaatccgat caagaaaatc
    43441 caaggggtga ttacaggact aacaacgaaa aagacaacta aagaaaacag aaatgcaccg
    43501 atcgtcattc ctagtgtttg ttgattggca tcgccaccaa ttttaccact tactaaacca
    43561 atactacccc atgccaacat agggactaat gctattaaaa tttccataac caatctcctt
    43621 ttatttcaca tgataagaaa cttatcagcg aaaacgttaa caacacaagc actttttttc
    43681 gtttctaacg attttctaac gtttttcatt ataaaaattt aagattggga aaaataaagt
    43741 cattgttgtc ccttttcctt cagttgattc agccgtcaaa tggataccta atttttcggc
    43801 cagatttttt gctaaataaa gtcctaatcc tgttgaatgt gttttgctaa gtcgaccatt
    43861 tctcccagta aatcccttat caaagatccg tttcaagtct tccgctggga taccgatccc
    43921 tgaatcttta actgaaaggc tgactccttg cgcttccttt tctatgctca caatgatgtt
    43981 tccgtgatcc ggcgtatatt tgatggcatt actaagcaat tggttgaaga taaaagcgat
    44041 ccatttagca tcggtcaaaa cagtatgatc ctcaccaacg atctcgtagc gaatattttt
    44101 ttggataaaa taatttgcct gactgcgtat cacaggctga atgattcctt ttagtccata
    44161 ttcttggatg aggtagtccc gcgagaaact gtcgagtctt gcataataca aaacttgttc
    44221 tacgtattca tcgatttttg ataattcatt ttctagtaat gtatactttt gatcgtcaat
    44281 atcgaactcg atcgaacgaa ctagcaattt agaagcggaa agtggcactt tgatttcatg
    44341 gacccatgag tcaatataat ctttttggtc ttgttgatta ctgattgctg attgcattac
    44401 ttcttggtgt tcacggatca gctgattgat atattcttct accagttttt cttcttctgt
    44461 cctcccacca ctcaaataat tttgcaaagg ggaagttttt tgtatgtcgg ctaattttcc
    44521 ccaccatctt ctcttgctca agtaaccacc cagcagataa aaaatcagaa agacgccctc
    44581 aatcaaagct aaataagcaa ttgtgctcaa atcaactttg atgtttggcg ccagccacat
    44641 cacaaagatc gtcaatgcaa taaaaaacag ccatcccaag atcaatgtcc actgatcttt
    44701 caaatattta aaaaaattca tcttaaccgc tcatcctttc agggaacgat atatccctgt
    44761 cctacttttg tttcgatata tccttggata cctgcctgtt cgatttttcg gcgtaaccga
    44821 ttgatgttga ctgtcaatgt attgtcatct acaaatcgtt cgtcatccca cagtgctcgc
    44881 agcaattttt cccgacttaa gatctttcca ttgtgcttca tcaaaataaa taatagacga
    44941 tattcatttt tgctcaaatc aatgatctct ccgttgattt ccatacttcc gttgtcaaca
    45001 ttcaacgtaa tgccattgtg gctcatcatt tcactagata attctgtgta gttgtaagaa
    45061 cggcgaagta atgcattgat ttttgcaatc agtacatcga tttggaaatg ttttgtcaca
    45121 aaatcatctg cccccatgtt catagccatg atcatatcca tattcgtatt cctgctggag
    45181 ataaaaatga tcggtacttt cgatacttca cgtatttttt gacaccaata atagccatcc
    45241 aaaacgggaa gattaatatc tagtaataca agctgtggtt cttctctttc aaagtctgag
    45301 aacacttgat tgaaatcggt cgttccaaag gtttcaaatt gccatttctc aagttcctcc
    45361 atgatcaatt gtcgaatgat ctcttcgtct tcgactacca tgatttttgc cataaaaaat
    45421 ccctccatct ttcttcttgc tactacaata tcaaagaagc ccttgtgaaa caagttggct
    45481 tacctggaaa atgtcatttt agcaaacgtt aaaaaaaact ggaaatatgc gatttaatcg
    45541 cgtttgtctc ttccaagcag cttaaattta ttatgttatt cttaataatt ggtctattat
    45601 ctgttatttt tctttcgttg tttttgtctt ttaaattttc gataacacca ataaccgaaa
    45661 agcgttagca ctagcaatat acctagaagg agtataagta atcgataaag atggtatttt
    45721 tttgtctgtt ctatctttga agagacttct tctgtaaagg gaactcgtct tcctgtcact
    45781 agtaatcggt gagtgttcac ggtgtaaggt gtacaagtga taagtgtgac tagatcctgc
    45841 ttttctctaa ttgctaatgt atttgttttt gttggaagga caacaatttt ctcaacgact
    45901 tcataagcga gcatccgacc atacacttca agatagaatc ggtcatcttg ctccatttct
    45961 tcaagatccg taaagagttt tttctcagca ataccgctat gggcggtaat cacggaatgt
    46021 gtactctctc ctccagttgg aaaagaggtg ccttgcagga ctgtcgctcc tctatctaac
    46081 aaaagatcat tcgtttcatc aaataaaggc aagctaacat tgattttcgg aatatagatg
    46141 gctccgatca tatgttgttc gtaatattct tttcctggat tttggacatt tctaaccgct
    46201 tgctcaaaag gatctttgac ttgtcccatt cctgggatta ctgatgtatg agcaagcgtc
    46261 tgatttttct tttcatgcac tgctaattgt tgctcatgtt tttcttcttt atcgcgttca
    46321 agctgctttt gataattctc gatccttctt tgatccaaat aattgctgag agcatctgct
    46381 aaaaatggat atgtaaaaac tgcagctccg gcaagaaaca tcactgccat aaataattgt
    46441 aataaaagac tgatttgggt ttgaggtcta ttacctattt tctttttcat tttcttcacc
    46501 ttcttattta aaaaaactgc agcaaccttt ataaaaccga ttgctgcagc ttatttttgt
    46561 tgcttatact tcagacttca ttttagattt acggtaccag ctgtacgctc caatcatcaa
    46621 acttattccg attagtaaga atgccaagag cccgttccca ccagtagcag gaagtgaccc
    46681 gcgtttcata ttcggtactc tttctggccc tggattttct actcctacga tctgaatttc
    46741 ttcattatag cttccataag agatgataaa ttcagtaaag gctgcctcac ctgttggaag
    46801 tacataacct tctggcgcca tggtctcttt catttgatag gttccataat ctaacccttg
    46861 aacctcaaag tatccatttc catctgcgac aaattctgtt gcttgtccgc ttgttgccca
    46921 ctcaattcta tctgctcctg attcataaac agctaaaggc gactcccctt tataaaatat
    46981 tgcgtattca gaacggtctt cattccacaa ttcgaatctt gcatctttaa gcaattcact
    47041 gcttgatgca tcatattttt caaactttct tccacctgtt gtgactttct ctggcggctc
    47101 tactccttct tcataatcaa attcatcatt tcgtccgatt tcaataaccg ctgtgttgtt
    47161 atggaaatca tccgcttcta gttctgtgga aaccttcaaa ttatacgtga tcgttaaatc
    47221 tcctccacgt gcatctgcta atctacctaa agtatctact ttggctactc cattttcttc
    47281 tgtcaaaatc gtcacgacaa acccgttgct tactacttct actatataat cttgtccttt
    47341 tgttaaaatc gtctcgccgg ctcgcacttc tatttcctga tcataataag ttagaccaac
    47401 tgtaggcgta tctgtgattt tgtaattttt gataacagcg cttccgtttt caaggacaga
    47461 atcgatgaaa taaggaatag gtgctgtgat cgtgtaagaa gccgtttttc ctctttctag
    47521 atcaatataa gaaatcgttt cttgttctcc agcttcatta ataatcgtta cttgtctaag
    47581 gtcgctttcc tctacattca tctgtttatc tgcttctctg atttcgtttt tcggatacaa
    47641 atgcacatct gtattgtatg tgtctttcca tgtagaacca tcccacacgc catccaccat
    47701 atcaggcatc atcactggca tcataacaac cattggagac gcgattctgg aaatatgagc
    47761 tggcgaataa gtttctaaga aaagatagac tttatctcta gaagaaggtg cttcttccgt
    47821 cacttggacg gtagagaata ccgcttctcc agcttcattc gttgtttgtt tgtcaatact
    47881 tgtcagtcga tattttaaaa accaactttc tgtgtgccgt ttttgaatcc attcaatcgc
    47941 ttcggcagaa ttaagaccgt cttctcgttc cggtgttaaa ggattatctc gaatcaaatc
    48001 gtaatatact tccgttacgt caaacaaatc aaaatcgact cctggaatat tttcttcacc
    48061 aaaatccgta gaaaccaatc cgctattcgg tcgttcttcc ggaacagatg agaaaccttt
    48121 tttgtgtaat gtaatcgtca cttcacttgg tttttgtgcg acttcttcgg ctttgactag
    48181 ttttccgttc ccgaaaatcc ctattcccgc agtaacgagt aacagtacac tcattcccgt
    48241 gacaatcatt tttttattca tttttttctc cccgttcttt ttttattaat aaaacagcac
    48301 ctaacaataa aagaattcct agtaaagaaa tcaacgttct tgcttcattc gtttgcggga
    48361 atacggacca ttttcctgat tgacctggat tgcttggacc actcggctct ttcggtttgt
    48421 ccgttgtttc ttttacggtc tcgttataaa cacgtggtgt tgcggattca taggcagaga
    48481 ctggaacttt cccggattct aattcagcca tctcctgtcc gttaactact acatattgtg
    48541 gttggccttt tgcatccacc caaaattcag ggatgatgac ctcgattctc ttacttgctt
    48601 catccatctc gtaaccttcc acacctttta attcttcaaa ataataggtg ccagaaggca
    48661 agaaacgttg tcctgtcgta acaaggccct ctttatccga aatgaatttg cttacatttt
    48721 tgtcattcaa aggatcattg tctgctggtt tgatccattg atttttcaag tcattagcag
    48781 gagccatatc taaataatat ttcccccctt ctatcatctg atatagagca aaaacagcac
    48841 cttctaatgg ttttcctttt tcagttgttc ctctttgacg tccatacttg aagaagtatg
    48901 gatctcttag ataaccgaca tttttaggat agatatgaat ctcttgcagt tcctcggttg
    48961 attctgtcgg gtgataaatt ggcaaaatag cagcaattgg gatagctgtc tgatcgatat
    49021 caacatccaa tccaacttct ggatcaatcg attcttcgaa aatcaaataa actgcatccc
    49081 gatcttggtt tttcttaggt gctttgatac gtgcaatccc gtctcctaat ccgccaaccg
    49141 tatctttccc agttgttacc gaagtcccta tttggacaag cctttcttct gtgattagct
    49201 gacggatatt gtttctgttc gtttcagcga tttgctggac gaattcttta ggagtcatgt
    49261 tttcagcagc ttttttttca tgataataat cggtcatgtc gtaaatggca aatgtcgctc
    49321 catttagtgg caccgtctgt gaaatgatat ctgctgtttc ccctgcttcc tcagagatag
    49381 ccaagccatc attttcatgg tattcaaatt gatcgttata atcgatatct cgaatcatcc
    49441 gtttatgcaa cacgaattcc acgacatctt cccctgattc ttctgccgac atcgcatgtg
    49501 gaagaaggac tgctgcaagc ggtagtaaaa caagtaattg aagcatcaaa cacaacagct
    49561 ttttcattac cttgctccct cctttttaga ttgtctgaca aacaaaccat aggctgctcc
    49621 tgcaagcgcc atgaagaatg cagcaagcag gatatagaat aatcgtccgg atcctcctgt
    49681 agcaggcaac ggattttcag gatcgttccc gacactaagc tgtaatctga ttcgatttgt
    49741 ctccaaaagt tcatattcta actcttgctg tagatcaggc gtctctgctt cttcgtttgg
    49801 ataatacgaa atctcaactt ttagtgtacc cgcttctttt cctggaacta cccgatcatt
    49861 ttctatgtca ggttcttctc gataactaat ttctaaaata aagtaacctg gaagttttct
    49921 atagctgtca ggtgacttca cttccttgat ccgatagacc ccttccaaca agtctgaagc
    49981 attgaatagg gaagaatcgt ttggatctgg tgccaagcct ccctcgatga tttcatactc
    50041 tcctgcacta ttttgtttct caattgaaaa ttctgcgcct tcaagacgtc ggctattcat
    50101 actgtcaatt ttcaaaagtt ccaaatcgat tggcgctagt tcatcttcta aggttacttg
    50161 tagtacacca tcgatgattt catagccttc cggcaaggga gcagtttcgt cttcgatgac
    50221 cgtatcttca atgataaact taccttcttc attcagtgca aactggaaca cttgatcaga
    50281 tagccgatac ccatttggtg cgacagattc cgagacctca tattcaccaa tagacagatg
    50341 cagaggttgg tcgtaattta aatcgacata cttttctact cctacggcac gagaatagaa
    50401 gtatccgatc ccaggcaaac gtttcgattc ttctggttct aacggattac cagtgtatgc
    50461 tcgatacagc gggaaggaag aatcccccac tttcctgata tcgaaacctg caccatctaa
    50521 tgtatggcct tcatggtcta attttctaac tcggatctcc cgataatcaa acgtattgta
    50581 agcagtgaat gctacccata aacgatcctc ttcatctgtt gtatacgtga gatattgcca
    50641 attttcttca cctgtttgct tgagttggat agtccctata gcattatcgt aaagtcgcaa
    50701 gatccatgtg tcattttcat caggttcttt gaaaccttct gggttctggc tctcaatgat
    50761 tttgtattct gcatagttgg tagtttcttc actatcctta taaacaaatg aatctggctc
    50821 tccgattgga tgaataactt tctcaccatc cacgattaca tatttcccgt cttcatctac
    50881 tgaatagaac gtgagtctcc ctttctcttc ctctacttcg ttcacaccag aaagcccttt
    50941 cgctactgga tatccgattt ccagtccgtt accatctgtt tcataaagtt caaactctgc
    51001 gccattgatt ggcatattac tgccttcaat tagtttattg atattcatgt ggattggctt
    51061 gaattcattt cgcatttcca gtttgacata caactcatca tactctgtgc cttctatgtt
    51121 aggctcttgt acaacagaaa gcttgtgata ttctccttca taataggaat tcggatcttt
    51181 accttccggt ccgccgactc tcgaaccaga tgtatattca tctacaagct cgtagtgacc
    51241 taacatctca tcttcgttgg ctgcatattt tttgatttgg aattgatacg tctcatctac
    51301 taactgataa cgtggtggtc cagcgatctc tctgatccaa aatatgtcgc tgactgctcc
    51361 agtttcatct cctaaaatcg gcatcttcgt ttcaaagatc gctattccgt ccgtggtagt
    51421 tttacttgtt tcgattggtt cggcttcccc actctctgga ttttggtcat ataatgcaaa
    51481 ttcgactcca gccaacggct cgccattttg acccttcttg ctgacttgga aattacggcc
    51541 tttatgttcg taacgaatgg aagaagatgg gaaatacatc cgtccagtag tgatatcatt
    51601 ctcataatcc tccaggttct gaatataggc catattgttc actgtgcaaa aatttccgtc
    51661 ttgagctccc gcatcaagtt ttacttggta cttgatcctg accatttccc cttcacctaa
    51721 agaaatcgga gaaaatttat aagcttggtt ttcccgtccg acatacgttg tcggagtcgc
    51781 cactacttct ggtggggctt gtccatgacg ttcttcatcc catatttctg gctcttggta
    51841 cttcatgccg ttttctcctg gatctagatg gtaaaactga atatctgccg atctgccagc
    51901 tccaaatggt gagacattaa aaccagtttc atcataaagt gtggcttgct ggatcgttct
    51961 cttgaaggta gaagagatat cctccaaggc tgtaacaatg tcattcttgt tgttcgcatt
    52021 gtaatatcgc ggtgttacgc catcttcttc taaatcagca atatttttca atacatttcg
    52081 tccaatagca tctagtcgtt gtctcccgct aacgtttcca tcgattccta aaccaatgga
    52141 gaagatactt ggcgggttct cttgatactt gtttttcagc caatgatgat aagcaactgt
    52201 gttgatcgca gatgactttt cttgcgaagt aggactgcca ttcgtattgt tattagaaga
    52261 accatcacca acccagtgag tcgctttatt atctccttct tttacctctc cataacgata
    52321 gtgtacattt acttcatctt ctggacggtt aaagtcagat gcataggtaa ctggatgagt
    52381 aaaccctgca ttagaagtat tcccagaaaa ctcctcaaaa tttctgaaca aaacgtcatt
    52441 atcttcagca atcttatctt ccatcacagt ccagttgctc caagctccat tagtgctcgt
    52501 acgataactt gactgaatcg gtgcataact gaaggtcggt gtcccatctc ccacaacgat
    52561 taggattttt tctggatttc tattttctcc gccattgtct ttatacaatg tttcatagcc
    52621 atttttaagc cctagtgtaa gcggagttcc tccgattggt gtacgattta atgctgtatt
    52681 ctcacttccc gtcaaacgat tgatatcatt tgtcaatgga aagatgtccg aactgatttg
    52741 ctcatggtta ttgatagctg tactattatg gtaaaaattc accataccga ttcgaatatc
    52801 cagactcggg tcagagagca gatctttact catttcgttt actgcctcaa tcaacgcagc
    52861 atttttagtt tgactattgg tcccagcggt taattcactc atactcgctg acttatctag
    52921 aacaaaaacg atatcgattg gactgatttc ctttttctcg cccccgatga catctagata
    52981 gacattgtaa agggttgttg catcttcagg atgtagatca gatgctgtgc tgcttggcag
    53041 aacaggttct acccattttt tgatgtacgc cccgttataa tccaagtaac tgttttcaaa
    53101 attccgttca tttccccaaa gctgaacggt ttgagctgga acgtttctat cttcttcgcc
    53161 tgcagttgat ccattattag tagcatagtc gtaatttcgc cagttcgctc ccccgtttgt
    53221 ataatcacta tcatcgatca agttctctcc gtcatatggc gagcctttgt ctccttgata
    53281 gcgttcattg ctttgtgtcc aatttcctaa cacttttgta tagtcattcg ttgtaaactt
    53341 cgggtagcga tgctgttcgt tttcaacttc tccgctagga tagatatatt cataggggtc
    53401 ttgcgtagct gttggcccaa gacgctccaa aataccgttg aataactggc gttgaatgcg
    53461 ctggagtgct tgaccgctgg gtacgattgg ttcgtccagc ttttccatct cattttcttc
    53521 gctacgttga atttcagcgg aatcttctgt atcagtttca ttttcttgta attcttggtt
    53581 atctattctt tcatcaacca ccacttgaag aggtagttac ccttcgttca catcggggat
    53641 cttttctgtt tcaaaaatca atgtgccggt ttctgcttct tttgaataaa cttttccgac
    53701 ataccattct tgaccatcga tcgtctcgac ttttaggtct tctccatctt catcatagga
    53761 ggatagacct gttccacgaa cgttttttac ggtaccaatc ccggcggctg ccgcatcgat
    53821 tgctaaacgt attctacctt cattggcact ttcctttttt tcaaaagcca gatgccattc
    53881 aagggtttct tctttttcaa tatacttccc ttcaattttt gcatagtcct catctaagaa
    53941 tacctcatcc tcctttgttt ctgttgactc agcagctaca tccagggtcg tcatatgata
    54001 gactgactgg aaatatggtc caaatagcaa actgacagtt actaactgca aaagcttcaa
    54061 ttttaaccct ttcacatcct tatactcctt tcaaaaatat ttgtcttctt tcacaacaat
    54121 caacaaaaca atgcccatct aattataatt taatttaatt ttaattttaa atcaaatgat
    54181 atccttttta gttaaaaaac accaattata caacatttat tattaaaatt aaattataaa
    54241 attttataac gttctcattt aacaaaactt aagttattaa gacaaatgaa taaacaacta
    54301 cgctttcctc gaaacaaaaa aataaagcac aaatgcgcat ttacgcactc atgctttatt
    54361 cgtacaatta attcagataa cggcagcgca taggatgcca ataacacttc ctaaaatagc
    54421 tcctcctaaa atgtcagtag gataatgtaa aagtaaaaaa atcctcgaat aagcgatcaa
    54481 acaagcaaat aaaaaggcta atattcctgc aactggactt aattcgaaca acgcagctac
    54541 tgataaaaag gctagcgctg tatgtcctga aggaaaagaa gaagtcttcg gtttacttgt
    54601 gtaaaggaca agccgacgat ttttttcata aggtcttttc cgtcttgtcg tttttttgat
    54661 aaaaagcaaa ccaacaaaaa aatagatcaa actgccgata agaatggcta gaccatattc
    54721 tctagtatca ggtatcaaga ctaaaacagc agcaaggagc aaccaaataa aaccaccatt
    54781 agagatatta ctgataaatt tcaaaaaatt gatttttcga ctatccgttt tccgttgctt
    54841 ggcgaacttg ttgataatac tatcatcgat tttagcaatc aaacgcaaca tgttattcct
    54901 cctttttaag aaccttttct tgcgtacgat ggataaaaag caggacttga aaataaaaca
    54961 agaaactgaa acctaataaa gcaaaataga ttggtcctgc aaaccagaat gcgacaagaa
    55021 ggatcaacgt gcctgccaaa tagaaaagcg cgcttttgaa atcattaaaa aacaagaaaa
    55081 atgcagtaat ccaagaagct tctttttgtt ccagttgaag caagattttg taactaaaga
    55141 gaagcgcgct taatagaagc aaaaacaacg tagtatacat caatgtatag ccaattcccc
    55201 caccccaata gcggaaaatc tgataatcga tcaatagaag aagaaaataa acacttgcta
    55261 aactatcttg ctttccataa agagagaagt tctcacgaaa ctttttccag aatagtgaac
    55321 cgagcttttt ctcttcattt ttttgtaatg ataaatcata tacagaactg ttcgacttgc
    55381 agttcctaat gtgaaaacag gcaagacgca caggaaccat agtagctgta aatggataag
    55441 acgtggaatc cattcaatga tttctaagaa ataatcattg gcttttttac caatcgatcg
    55501 attcatcatc cttttgaacc tcctgtcaaa tccatccctt caatgaaata acgttgtgca
    55561 aaaaagaaca gcaaaatcgt cgggatcaag acaagtgttg ctcctgccat cagataattc
    55621 cattgtgtcg ttgcttggtt ctgaaaaact tgcaagccaa tctgtaacgt gtatttttct
    55681 tgatcttgga tatataacag aggacctaag aaatcattcc aagctgcgtt gaaggaattg
    55741 atcgcaatgg taatcaaggc aggtttcgtc aatggaagca tcaaatgact ccaaatatac
    55801 aaatgattcg ctccgtcgat ttcagcagct tcgatcaatt cattattgat cgataagtaa
    55861 aattgacgca tcagaaatat attgaacgca ttgccgaaga acgatggaac gatcaggggc
    55921 aaataagtac ctacccagcc gatcttggag aataatacat attgagggat catcgttaca
    55981 aaccccggga tcatcatcgt agaaagaacc aaagcaaaca tcagcttttt cccaggaaaa
    56041 tcaagcttcg caaatccata agcaataaaa gaatttgaaa ggacattacc gatcactact
    56101 agcacagtga tgaataatgt atttcttgca tagcgccaaa aaggaaaggc ggcaatcgta
    56161 tccagatagt tttcccatac gattttttct gggaaaaagg tcggaggata acgaacgatt
    56221 tcttccattg gtttcaatga agtaaacacc atccaaagca atggaatgat caaaatgatt
    56281 cctattactg tcatgaggac ataacttagt atttttttgt ttgccgattc acactggtct
    56341 ttttgaaata atccatcatt tgccgtcacc tccagaataa tagacccact taggtgcaag
    56401 cttcaaattg acaaacgtca gaaccaacac gatcagaaac aggatcattg acatagccat
    56461 cgcataaccc atatcaaaag ctacgaacgc cttgttccac atatgcagat tataaaaaag
    56521 caaagaattt gcaggtccgc ctgttccatt tttcgtcatg acataagctt cttgaaaaat
    56581 ttggaaagaa ccgatcgtag aggtgatcac atcgtaaaaa ataataggag tgattaatgg
    56641 caaagtaata cttttgaact ttccccaaac gcctgctcca tcgatttctg ctgattcata
    56701 taaagatcta ggaacatttt gtaatgtagc taagtaaagt agcattgctc ctccagaact
    56761 ccatattttc atcaaaatca acgcaggttt cgtccattgt ggatcaaaca gccaagctgg
    56821 tccagggata tggaaccagc ccagaaatgt gttgatcaat cctgcagatg gagaaagcag
    56881 ctgcatccat aagatgtaga ctgctactcc tgataagact gccggtaaat agaaagctgt
    56941 acggaataca ctgattcctt tgattttttg attgagtact gtggctaaaa acacactgaa
    57001 aatcgtcgtc agcggtacat tgaagatgac gaaataaacg gtgttgtata acgatttcca
    57061 aaataaatca tcgtgaacga acattctttt gaaatttgct agaccaatga aattcatctt
    57121 ggatgtcaaa ttataatcgg tgaaactacc aataactgaa aaaagcatag gccctagcat
    57181 aaataccaag aacccgataa taaaaggcga gataaataaa taggcccatc ttgcttcttt
    57241 tttctttcgg atagataaac gcttcaaatt ttcttgcctc ctctgtacct agacagtcaa
    57301 aaatggatta ttgattttgc ttgactaagt tttctactgc tttttgtgca tctgccaatc
    57361 cttcttttgg tgattttgtt cctaaaagaa tctggtcaat ctgttcattc actaatgtcg
    57421 tgtaatccgg agcatctaaa ggaactggtg tgatcaccgt atttttaaag ttttcgtccg
    57481 ccatttgata gatcattttt cctttatccg ttaggttgtc attattcact aaattctcat
    57541 tggctgtctt gctcgccatg atatcaaaac ttttttcgcc gaatttttct tgtacttctg
    57601 gagaagaaag atatttgatg aattcataag aggcctcagg atcttttgct ccgtatggta
    57661 cttccaagac gaatccgcca ccccacgacc aatggcctga accttcttct ttttctggga
    57721 gctgcatcac gccaaaatca aaatcatccg gtgcattttc catcaaacta gagtaataat
    57781 tgatattttg ggcacgcatg gctactaatc cggaaataaa tggatcagat acaccagacc
    57841 caaattcggc ttctaattta ttgatcgtat ttttcccata ataatcttgc cagtcttgga
    57901 tccactccaa ggcttccact ttatttttag tatcaatctt gactttttca tctttgtcaa
    57961 accaactagt cccgttatct gcgtttagcg cccatacatc agcccctaaa ttccataatg
    58021 gataaaaacc gatgcgtgta aattcttttc cttctttttt atctagttta cgtgctgttt
    58081 cttctaattc atcccaagtt gtcggtagat cttgttcact gattccagct tctttaaata
    58141 tctttttatt ataaaaaatg acttgtgtat ctgtattgaa tgggatcgca taaggatcac
    58201 cttcatattc tactgtatcc caaagctgcg gataaaaatc cttagaagtg tctttttcta
    58261 catatttgga gagattagtt gcttgctgtg cttctgctct ttgggcaacg gaatttatgt
    58321 cctgtacaat aacatcgggt gcatttccag ctgttattgc agataaagat ttagtccaga
    58381 tgtcacccca tggctgatac ttataattta catggatctc gttttgtgat tgattgaaat
    58441 cctcaatgat ttcttcgata gcttcttttc gtgcaccgga tccccaaaag gaccagaaat
    58501 caatattttt tcttccatca cttgtttttt cagaagaatt tgctgcactt gaactggcat
    58561 cgcttgcatt acttgatccg catcctccta ataaaaacaa tgctgaactt gccagcaacc
    58621 ctgtaaacaa taattttttc atattttacc tccaaatttt aatgtaaccg atgccggttt
    58681 taatataacg atatcatttt gttctgaaaa taacaattta taaggtatga ttctaaaaaa
    58741 attattaatg ataccaatac tttatataat tcgcgagcgc tttctttgaa ttttttaatc
    58801 tttcgtagca gaatgagaat gtattaaaaa tagattagga ggaattttga tgtttagaca
    58861 ccagaaagaa ttgcagtttg aagcaaaacc agatcgtccg aatccattaa tcgcgaaata
    58921 tctgcaggag ctgatcggcg gccaatatgg cgagatgagt gtagctatgc agtacctgtt
    58981 ccaaggctgg agctgccgag gagaagaaaa atataaagat atgctgatgg acattgcaac
    59041 agaagaaatc ggccacgtgg aaatgttggc gacaatggtt gctcgtttat tagagggtgc
    59101 gcctgttgaa gatcaagaag cagcgatgca aaaagatcca acaatcggtg ccattatctc
    59161 tggaatgaat ccacagcacg cgatcgtagc tggcttagga cctcgtcctg ctgacagcgt
    59221 gggcaatcca tggagcggtg cctatatcat tgcgagtggc aacttgttag cagactttag
    59281 agctaattta aatgccgaat cacaaggaag acttcaagta gcacgtattt acgaaatgat
    59341 cgatgatcgt ggcgtaaaag atatgctgtc tgttctcctt gcaagagata gctatcatca
    59401 aaatctatgg gaatgtgcag tgaaagaatt agaagaaaaa gaaggttcaa tcttagtccc
    59461 aagtactttc ccgcgtgaca aagaacgaaa agacattgct tatgacttct ataacttctc
    59521 agagggagac caaagtagtg aaggttcttg ggctagtggc aaagcactgg atggcgaagg
    59581 cgaatatcaa tggttgaaag aacctaagat cgaaggcgct gcaccaaaat tagaaccagt
    59641 aacaccaaaa atgtatggga cacctccatt caagaaataa atatctaccc gtagaaacac
    59701 ccgttttttg ttccacacgc tttgtgagca aaactgacta aagtcattaa tcataaccac
    59761 ccttcaaaag ggtggttttc tctagagcta taagctcaaa tcaccggcca gcgcctaaag
    59821 acgctggctt tcatatttta tgttcaagcc atattgcctt tgccagtttt gcccacctct
    59881 taaaaggttt atgtactact ccttagccct taaaaggatc gtcttactct cgtacactca
    59941 gcttatctaa cgcactatca tgtttttctt gttcttgaat gtactttttg atggtcgctt
    60001 cattttgtcc tacttttgtc acatagtatc cttccaccca aaagtgtcga tacccaaatt
    60061 tatattttag atttgcacaa tctcttgatg atctcctgaa tattggctcg atattgatta
    60121 taaattattt ttcttctata ctttggtgtg aatacaatgt ggtatttaca catctacttt
    60181 gtacgggcta aactatttcc ctttattgct ccacccgcat agcaagtggt tttgtatttc
    60241 aatcgctcgg cgcgctcaat taggtctaaa gacaataaat ctaaaaaccc gctgcttcac
    60301 tgacagaaac aacgggtttt cagaaaaaaa tgaaatgaaa aagatctctt acggcaatct
    60361 attttatttt tttgattttt tataaatgga aaatgcttca agaagtccaa gaaataaagc
    60421 cgtataaaaa caagaaccta tgaaatcttt atttattaga tattcaacag aaatcccgat
    60481 aacactagcc aacaatatat ttatcagaag tgtaaaataa ggatgctttt tatagaatag
    60541 aactagtgtt gttttcatag actctccttt cttcatattt ccaattaatc acaaattcac
    60601 ggcattacta gaaaaattaa aggggcgcag aagtggaaaa atactcttcg actttcccta
    60661 caaaccaggc catcttgtgt ttaataacta taccaaatct aaggtacctc taaatctaaa
    60721 ttccatttgt ggcggtgacc tccaattttt aactcttcta tctcccatcc agtatacata
    60781 accttgatac ttcgaccact tatatatcga acacacaaat acctatccat tgcaggagta
    60841 ctacctaact tagttgctac ttgcatctaa ataacagctg aaaagatagg acttactctt
    60901 agtaaagtat ctgaactatt aatttttaaa ctatcatttt tatcctcaac tacatgcaca
    60961 tctgttgcaa cttcactttc tgtctcatcc agataaatga ttaaggaatc gggaattgca
    61021 atatcttcag ctgacgctgg aatagttgag ctaaattagt catcatatct ttattataaa
    61081 ataaccaaca gcaaaaaata caatgaaaaa caaacttgga actaatgtat cattaataaa
    61141 tgttgaaaaa ttcagcaact cattactgta tgattttagc agcccaacca acatataccc
    61201 tataaaagct aataagatgg ttaggaatcc tttagaattt ttactcattc atagacactt
    61261 ccttaaataa cttttattat agaaggtatt gtaaataata atattgacaa aaagtgactc
    61321 aaaataaaaa aaaccttaca ttatactgga atgaactgta ttgatagtgt acctaaaagc
    61381 tctactgaca taagatcgtg taatcggtaa agtaatttta ttaattatac gggatgtaat
    61441 caattagaga ataaactaat cataaaaggt acttttacat tcataattgt cgctttgaga
    61501 ttctactttg gttcactatc tgacccaatt gcacattttc gatcattaca agtattggtg
    61561 tcgttagaac aactaaataa aaactagcgg tagatttttc agaatctatg ctaatttctg
    61621 tatggatgtt ccagtgatgg caaatttctc ttttcattgt ttttcttgtc gcatgatatg
    61681 cctttttgtg ttattcagtt aaactataga aattctttcc tagacagatc ttgatcccaa
    61741 attttacgtt tttgagcatc gatatagttt aaaatgacat tactcatatc taaagagttt
    61801 agatttttta ggactaaaac tgtcagttgt tctttttctt ctttctgtta aagtattgtc
    61861 gcgacttttc gtatacgtta agatatgtcg tgaaaaaaca agttttgtga cacaaaaaaa
    61921 cgaatgactt gaggaaatca cctcaatcat tcgtttaaaa tgctatatat tctttagttt
    61981 aagatacgga aattaatgcc atcgaccaca ctagtagaat gaacgacatt tacttggcct
    62041 ttttttaatt tcgttatgtt tagcatataa aaatattata gagtttactt acaatgctta
    62101 aaacatatac tgtataatct gatcaatttt agccatgtct tgcaatggta agttttctat
    62161 ttttttgagt tttcgttcct taaaatcaag agattttaat tgtgtaataa ttacttgtcc
    62221 ttttatatct agctcttcag gtaatgagta acgtgtcggt aaattcttta tagtggaagt
    62281 aattggacat atgaccgaaa acattgtttt acggttaaat tcataacgag agacgactag
    62341 tcctggtcgt cttttttgaa tttcttttcc tacggaggga tcaaaatcaa tccatacaat
    62401 atcacctttt ttaggaatat aaattctttc ttctgacact ataaaatttc tctcccttca
    62461 ggagttaaat cttcccattc gtctttctca taatactcgg cctcttcccc accactaaat
    62521 ggatcttcaa tttttggaac taacgtaatt gttccatcat cagaatacac aacgatatat
    62581 tcttggtttt ctgaaggttt ctttccgtta tcagaaggta aagttaccac tacagaactt
    62641 ccttgtaatc tagattttgt aacaagcatt atcatcactc ccttaataaa agtatactat
    62701 ataacactaa gtaacgcaaa attccccttt gtaaactatc tagaaaattg ttttgtttaa
    62761 agtatatctt attggatata aatagaaata aattgtagcc agttcatttt ttctttaact
    62821 aaaaaaataa tccaagaaac attgaaccta tggatccaaa agctacccaa atactatagc
    62881 taaccccccg ctaccttcaa ttttgcagat aaaacgcttt gggagaaaat ttcaaagaca
    62941 acaggccatc ctatcatgcc cgattataaa caaaaagctg gctattcctt ttgctctgac
    63001 aaatttcaat tgggaaagtt cacgaaacta gcaggtgaag aagtttcaac tgttcggatc
    63061 aaagaatgcc cgcttcaaat agaaacattg gttcaacgaa tttcaactag acaagacttt
    63121 gctattgtag aacgtgagat cgtagctatt tttgtagaag aagggatttt acatgatcca
    63181 actcatatca atgtggataa atggcaacct cttatctata aattcagaga atatacaact
    63241 gccaaccagt cgttaacttt gaattttaga ttccaagaat tcaaagagtc ataatgataa
    63301 acatcgttag gtataaataa aaaagactcg cagcacgagt aaaaaacaaa tagaagctat
    63361 acattagaaa ggtcgactgt gaccctatag atgcagtata tgcagcttat gagcatttct
    63421 tctgttctct ttgtttttgg gatctgtgct gaagtctttt tcgttttttg ccgctctttc
    63481 tttgaaaaat cgattatgtt ataccttctc cattactaat tcaggcatct gctgagtaat
    63541 gatttttcgc gcaaaagaaa tatctgttac ccaaggttcg atttgttctt cagtcaagac
    63601 aagcggcatt cggtcatgga ttggtgcgac tgtgcggtta ggttcagtag tcattatgat
    63661 tgattctgcc attttttcat cctgatggct acgataaaaa ccgccaatat acactatttt
    63721 ttccttattt gaaaacataa atttgtcttt ttcttcattc cactcattgg gaaaacacaa
    63781 cgattttgca aaaatggttg atgaaaggtc tttttttctt ctactgtctc tgcacgggca
    63841 ttaatcatca attgtccttt tttaaatccg gtaaatcccc acttcatgat ttccggagtg
    63901 aggatgtttt cttcctcttt tcttaacgtc acaacaagat ttgacggaaa aacttctcca
    63961 gctgctaatt ctgctgcctg cttcggttgt ttcgtctggg cttctcgata ataattctga
    64021 aggagctctg actctagatc aaaaaaataa cgaccacaca tcctaatccc tcccaatctt
    64081 tttttctatc atacactgca acaagaagtt cgcaccaaca aaacgctttc aatttttgta
    64141 gaactaaaaa agttgtgaca agtgacaaac tctccagtga atggtattct cctgccaact
    64201 cctcggtcac aagtcacaat attcaacaaa catgagaagc tgctttttga aattgttcct
    64261 tgtgactcgg agtgaaacgg caggcttacg acctctgggt aaacggtgtt caaaagccag
    64321 tttctcggta ttaagccaaa tttatgcaaa aatgtagaaa gctattttca caaaattttt
    64381 cttaatactc gaaactaagc gactttttca caacctcttc cttaaacggt gttcaaaagc
    64441 ttgcatctgc ggtaataagc ccaaccaaac gaaaaatatg agcagctatt tttatttggc
    64501 tgttcttatt acttgatgca gggcagcttt ttcacaacct ctccactaaa cggtgttcaa
    64561 tcagctaacc ttcggtatta gctcaaaaaa cggcaaaata tgaggaacta ttttgccgtt
    64621 tgtttctcta atactcaggt caaagcgctg atttcacaac ctctaataca cggtgttcca
    64681 gaagtagctt cttcgaaaaa taagccgaaa tttcacaaaa atttgagaag caattttcgt
    64741 aaattccttc ttatttcttg aagctgacca cttctgtcac aacctctaat tattaaagaa
    64801 ccttttgcga agttaacaat ctttctttga tcaattgaaa attctgccta agtagtgata
    64861 gatcctgtgt gactttcaac aataagatac ttccctggat ttcagcaatc aacgctttgg
    64921 cttgacggtc tgcttcttca tcggacagtt tttcttcaga aagtgccagg atattttgtt
    64981 tcgtatactt gacccattga ttgactaatt ctagtagcaa cagacggtat tcttcatcca
    65041 ctgtactcaa ctcaataatc aaattaccta caggacaacc atgataagtg atctgtgtct
    65101 catgatcagc gaaaatccag tccaacattt cttctaatgc ttcttctggc tgttttccag
    65161 catttaagat gtcttcgaac aattctgtct gccatacgtc catatgcgca tggatcaccg
    65221 ctagacaaac ttcttttttt gaagaaaagt aataataaaa ttgacctttt cctgtatcag
    65281 aagctgctag aatatctcgg attgacgttt catgatagcc ttttttataa ataagatctt
    65341 tggtcgcttc caagatcttt tcctttgttt tcaatgatat tctccttttt catttctcat
    65401 agtcctatat tatacagtaa attcatcatt ttttcttctt aatcgtttaa aaaagactgt
    65461 gccaaattat ctgacacagc cctcactata aaactgttct catatagcta gatgttcatt
    65521 gattcaagaa ctgcgaggac aaaagcaatt cctatcttat gatagttgct ctaatacttc
    65581 ctctgttgtc atcacttgat ctgcaataaa gccaaagttc gtcaacgctg catccattgc
    65641 ttcttggcca ggagcaccaa ttgcatctgt cgctaccaca acattgaatc cactctctac
    65701 caattcacgc atatgggaat cgctacacaa gtttccgttc attccaccaa gaattactgt
    65761 gtcgattcca ttttttctca attggagcgc caaatcattg ctttctggtc caaagatttt
    65821 atgaggagag ctgatgatcg tattttcatc caaataaggt ttcaattctt cgataaaatc
    65881 ggctcctgaa ccttcttcca ctgattcata ttgacttttt ctagcaaaca tctgctgctc
    65941 aagcatcata tgttctcctg caccgccaaa ttgccattta tggtcatgtg ggtaaaaata
    66001 atgaggagaa ataaagagtt tgtatccttt ttcttttgct tgttttacca tttcaatcat
    66061 attttcgatc gtattgtatt tttctaagat atcttttgtc aaaccaaagc caccgcctgc
    66121 tggtttcaag aactcgactt gcgggtcagt gagaactact gctgtatttt tattattgaa
    66181 catggtggat tctccattcg ttatttattt taatacatca tttagagctt cactcattgt
    66241 cggatgagaa tagatttgat ctctcaataa cgtataagga agttttccat tcatagctag
    66301 cgaaatcaag ttgatgactt catgagaatc ttccgcatag atacttgccc ctagaatcaa
    66361 gtcagtttca gggtcgacta aaactttgaa tacaccttta ggatcttcta atacttgtgc
    66421 tttagggaca ccgcttgtca tatacttgaa taatttgtaa ttgacgcctt gtgctttggc
    66481 ttgtttttct gttaaaccta cattggataa agtcggagtg ataaatacac tgtaaggcac
    66541 agctttccgg ttattcgttg ttcgtttatt ctcgcccttc aactgatcca taatgattcg
    66601 ataatcatct agagagatat aagtgaactg caatccgcct ttgacgtctc caatcgccca
    66661 aatgttgtct gcatctgtac gaaggtattc atccacagcg attgctccgc gatctgttag
    66721 tttaacatct gtattttcta atccaagtga tgctgtactt ggttttcttc cagttgcagc
    66781 caaaactttt gacgcttgga ttgttacttc ttggccatct tctgtaaagg tgacggcagc
    66841 tgttgattct tggtctgcta cttgatctac agatacacct agatggaatt cgattcccgc
    66901 atttgtcatg tcttctaaaa tcatttgcgc gatatcttca tcttcacgtg gaagaaattc
    66961 agaatgggca tcaagaacga caactttaga tccgtattca ttgaacattg atgcaaattc
    67021 caagccaata tatccagccc cgatgatcac taatttttcc ggtaattgtt cctgatccat
    67081 cgcttgcgta gaatcaatca agtagcgact tgtattcaat cctttgattg gtaaaatgat
    67141 tggttcagaa ccagtattga tgaaaatccg ttcgccttca acaatcactt tttcaccatt
    67201 attcgtcact tcgatttgat ggttagaaag aaaacgtgct gtaccgtcca tcactgtccc
    67261 agttgcctca tcgctgatca tatgataatt tttggcgcga agcatgcccg tcaatttttc
    67321 tttccgagca acagcctctg taaagtcgat tcctctttct ccattgaaaa tcaatgattt
    67381 agaaggaata cagccgatgt tgatacatgt tccgccatac atacgtgttg acttttcaac
    67441 gactaaaacc gattcacctt ttgaagctaa cgccttcgct aaagtcttac cgccctttcc
    67501 aaaaccgatc acaatatttt gatatttttc catcattttt ccctcgcttc ttttttacct
    67561 accgattggt acaaaaatat gataaccgat aattgtctat tctccaaatc atctgcttta
    67621 tttgtcaaaa aaaaccagac aaaaagcggt cctttcacgt ttttagtctg gttcgatttc
    67681 ctttattctt ctaaacaatc gttacttcta catcgatatt tcctctagtt gctttggagt
    67741 aagggcagaa ttcatgcgca tcttctgcaa ttttttgggc ttcttcttcg ctgatgccat
    67801 cgatatgcac ttctaatact acaccgatct gatagccgcc atcatctaaa ttataaagag
    67861 agacacgtgc ttttactgtg gactctgctg tcattcctgc ttctttgatc atatgttgta
    67921 ccgccccatt gaaacaagaa gcataacctg ctgcaaataa ttgttctgga tttgttcctt
    67981 ctgcatggat tcctggagga gtgattttca tatgcatcga gccatttggt gcctcgactt
    68041 ctccattgcg cccgccatgg ttgatcattg ctgtttcgta tgcttttttc attgtactgc
    68101 tcctttcgat tgaccatttg ctacttggct ataattatag tgtatgacaa gtaaggcgct
    68161 ttctacaaaa attctgctta ttcgaatacc agaatgccgt cttctactat ttttccaaaa
    68221 aacaaaaaaa tactactcgt gaacaacagc gtcatatttg ttccaaaata aatagcaatc
    68281 ttttctacat aatcttttat atgattgatt ttaagataca tatataccag aaagttgacc
    68341 ccataaacca atactgttaa aaaaataacc atattcgtta ccattttttc ctccttttgc
    68401 tggtctccct accagcactc gatttaacca taccactttt tttgccgtcc aagcaactag
    68461 cctttcaaaa agactggttt attctgctgt taatgattca agatcagaaa aatgtccgaa
    68521 taattttgct aattttacta acgccaactt gttctttccg aattcatcat tttctatctg
    68581 taatactagt aacggctcat gtaagcttaa acggatcaaa aaccagccgt ttccgtatgg
    68641 ctcttctaga tcatatcgaa taccttcttc attttccggg tcgaagttca tccctttttc
    68701 ttcttccaac agtcgcttca tttcttctaa tatcttgttt ccttgttcgc gtggttcatc
    68761 gctgaacaat tttaatcgga tttcttgtac ttctacgggc tgtttcaact ctttgatttg
    68821 ttcatctaat gtgatacctt ttctttttaa ttctggcaaa agcatcagga tctttgcgat
    68881 gacatatgca ccatcatcca gaaaatagtt ttccttgaat gcagcgtgtc cgcttgtttc
    68941 gatggctagc tgtgtatctt tcccaagacg gttaagttct aatgctttat tgattacatt
    69001 tcgatagccg gaaatataac gaacttggat gcctcctttt tcttcaatga atctttgtag
    69061 atgagaagaa gtaggggaat tcgtcacgat tcttgttcct ggatgctctt ttaatacgat
    69121 tgtacttaat actgcgatca aattatttcg attgatcact gttccagaag cactgacaac
    69181 tgcagaacga tccacatctg tatcgaaaat gatcccaaga tctgcttcat ttgctaaaac
    69241 agcctgcttg atactttcca tcgcttcttt attatcagga tttgggatat gattaggaaa
    69301 tcggccatct ggttccaaaa attgggaacc tgttgaatcc gcacctaagc tattcaatac
    69361 tttttcagca aagaatccac cagcaccatt tccggcatca acaatgattt tccaaccatt
    69421 tagtggtttg ctttctagtg ttccaatccc ctttttaatt tttgtgacta aatcttgcgc
    69481 ataaggtgtc aaaaggtctg ctttttctac gcttccagtt tgttcgcttt ttattttttg
    69541 ctgctgtgat aggataaaag caatatcttc tttttctgct cctccttctg aggtaaagaa
    69601 ttttattcca ttataataat agggaagatg gctagcagtc agcataaccg cagcatcgca
    69661 cgagaactgt tcaaattgag tggacataaa catagcaggc gtagtagcta attcgaaatc
    69721 gatgacatgt atcccttgtt ctttcagact ttggatcaac gcctctttca gtgctggtcc
    69781 gcttatccta ctgtcatgac caatcccaat cgtccatttt ttatttggat cggttgattt
    69841 cttctttttc tttatccagt ttgctagtcc ccagccgatc ttttttacca tgtctgtcgt
    69901 caagtttact tcatatcctt caactggtaa tgcgattcct cgaatatccg atccattttg
    69961 cagcgctttc atatctttca tataaaagtc ctcctcattt attccctcat tttttccagc
    70021 ttttctgcaa atcgctgtgc ttcttcttct gagcggcaaa taataatgaa tgtatctaca
    70081 ccggccatcg ttccgacaac ttcagggtaa gccacttcat ctagccaatt cgttaccaca
    70141 tcggcaccat ttcgttcagt caatacgata accatgaact gaacagactg gatacgcaaa
    70201 acctcgcgtc taattgctgt acgcaaacgt tcttcattta aagaaacaga tggctggtta
    70261 aataatgtat agcgtactat tttgttttca ttttgacttt ttactaactt catttctcga
    70321 atgtctcgag aaatcgttgc ttgagtcaca tcggcgcctg cttcatgcag ccgcgcaagc
    70381 agctcttcct gtgtcccaat aggttgttct gtaatgatct ggcggatcag tgcttgtcgc
    70441 tgtttctttt tcatattaga cacctctcaa tgttgattat agcaaaagat aagtaatatt
    70501 tcttcatatt ttggtatttt ttacttttat tttttgtttt cattcaggtt gctaaccttt
    70561 ttctatttta acacgcaaaa tcgtcttcat tttttcaggt gctgattttc ttggatcgct
    70621 gatgtaaatc tctttgtgtt ctttagaagc tctttcatag ccttcttttg cgatgaatgc
    70681 ttctaatttc tcaaacgttg ctggttcttc ggcatagggc ccgacgtgta agatttgggc
    70741 acaaagacct tcttccatct ttttgaatac tacttgttct ttcaagtctt ccggaagttt
    70801 gctagaacgc tgaatggctt cttgtgctat cgcttctgta acaaagtcag gctgtcggat
    70861 catcaattga taagaaaaat gttctttttt catcactggt tcatgcaaat acttttcttg
    70921 cagtccccat tgtccttcca gtggatagac agtatacatc tgataatcag gaatcagcca
    70981 atttttttta ggcgacatgc gtattgcata gctgactgca tatagacagg ctactcttcg
    71041 tttaaagtct tcctgattcg ggtcgccgat ccctctgatg ctaaagaatg attttttagg
    71101 aacctctagt atttgcgggc tttttttcat actatagctc ttgtctttac gccattcaat
    71161 tttttccatt tttcttcctc cgcgaaattc catttagtta tttattatca tacctctttt
    71221 tgagtgactt ggctaatcgt gttgacacta tttttcagtt tgtgctagaa taagtgaagt
    71281 aaataaatcg tacagataac acgtttcggc gtgtcgagag agaggcggtt tctattttta
    71341 taatagaaat cactctcttt ttttacgaaa ttttttagag gtgatgtaaa tgacaaaaca
    71401 aaaacagctg cttttagtac ctgcagtaat tgcaacaggg atgatgtctt ttgcgggcgt
    71461 attgatcgag acggccatga atgtaacttt cccaactctt atcagacagt ttgatttaac
    71521 gactgcacaa gtccaatggg taacaacgat ttatcttttg atgatttcga tcattgttcc
    71581 gctgtctact tatttgaatc gcaattttag tctcaaaaaa ctctttttag cttcaaatct
    71641 gcttttcttg gcaggtataa tgatcgattt cttctctcct accttcatgg tcctattgtt
    71701 tggtcgattg ctccaaggtg cagcgacagg tatcgctctt ccgttgatgt tccatattat
    71761 cttgacattt gcccccctca atcgacgagg cgcgatgatg ggtgtcggta ctttgacaac
    71821 ggccattgct ccagcaattg gccccactta tggaggcatt atgacttcac attttacatg
    71881 gaatcatatc ttcctgtttc ttgtgcccgt tttgtttctt tctttgatta tcggctggtt
    71941 tgctattccc gagatggcag tacaaaaaag tggttatttg gattggataa gcgttttagg
    72001 aatttgtctt ttgtttagtg gaagtctaac atttttgagt acgttgggaa cagtttccag
    72061 ctggattgct ttaatcatcg gcggtattgg ctggttcctt ttttactatc gaagtaaaaa
    72121 agtggagcat ccactgatcc gactgtctat tctttcaaat aaaacattcc gcttgttttt
    72181 gattggcttc ttagtttatc agtttttatt acttggtgta tcttttgtct tgccgaattt
    72241 ccttcagatc gttcaaggaa gtagtccttt tgtcgctgga ttagcgatgc ttcccggcgc
    72301 agcggttggt gctttgcttt ctcctttttc cgggaaaatg ctggatcaat atggtccgaa
    72361 gaagccaatt tttgctgggc tgattctttc tttgattggt tggctagcat tattcctact
    72421 cataggacac gcttcagtgg gtgtattgat tgcttgtcat gtgttttata tgatcggtat
    72481 cggattatct tacagcaata tgatgaccac cggaatgaat gcactgaatg aagaactaca
    72541 aggagacggg aacgcaatgt tcaatacctt gcagcagttt tctggcgctg tggctacttc
    72601 attagtagcg gtcattatca attacgtcca gcatcatact tcccataact atgaagtgtc
    72661 tactacatta ggatcaaaag cagcattagg cgtcttgttg ctgttgcttc tcgtaagctt
    72721 tgctcgattc gcctattatc tgttctttgc taaaaaagcg tagattccat atacggcagg
    72781 tgttgcatct gccgtttttt tgtgtgaaaa tggttgtttg taaaaggagg cttttttatg
    72841 gaaaaaattg ccattatcgg tggcgggatc attggtatga ccctagccag ttacttagat
    72901 acatcaaaat tcaatgttgc tttatttgat gaagggacag gacaggcaac taaagctagc
    72961 gctgggatta tctccccttg gttgtcgaaa cgcagaaaca aacaatggta tcgtctggct
    73021 aaagacggcg ctgctttttt ccctaaactt ataaaagatt tccaacttga tcaaacgatt
    73081 tacgcacaat cagggacact tttgcttcga cctgaaaaag atttagctga attggctgtt
    73141 cttgccgaga aacgaaaaga agaagcgcca gaaattggaa acatcgaatg gctttcacct
    73201 gaacagacat ctcaagcact tccgttattg aaaccagcag tttcactgcg tatcagtggt
    73261 ggtggtcgtc tggatggaaa agcatattta gaacatcttg gtcagcgttt agcacaaaaa
    73321 caaatggagc agatccaggc aaaagtcact ttgcataaga agagcgattc ttggctcatc
    73381 aagggaccgt ttggagaata cacagctgat cgtgtaattt tgacacctgg cccggcactt
    73441 aagcctttat tacaagaatt aggctatgct gcagatatac gtccgcaaaa agggcagctc
    73501 ttagcatttc agacatctta taagatgagt caagactggc ctgttgctat gcttgacgga
    73561 gaagctgatt tcattccttt catggatgga aagatccttt taggtgctac ccatgaaaac
    73621 gatcaaggct gggatttggc tcctactagc gaagcttata agggattgac taagagtaca
    73681 gaacagttct tgactgatcc agatcagata aaaaactggc catacgagtt ccgtgtaggt
    73741 acccgtgctt atacgtcaga tttttcccca tttttcggcg tactgccaga tgatccaagc
    73801 ttactggctg ctagcggtct aggctcttct ggcttgacca caggtcctta tatcggctat
    73861 ctattagcca acttcttaaa tactggtcat tggcctacgg aagattatca aaaggacatc
    73921 tccacctata ttacgaaaaa tccatcatag aaaaacagct ttttcaagta aggatcccga
    73981 gcgatattgc gcatggatta cttcttgaaa aagctgttat tttagttcaa tttctgaatc
    74041 aaattctcca aactttcttt tgcttcatct ggcaagagat cttttcctat ctgagcttca
    74101 atgaatcgta aacgaatatc aagtcgttgt ttcaccagat ttttatagga cgtatcctca
    74161 aaagaaacag gaaaatctgg tataggtaaa tagtggatgt cttcaaatgg accaaacgac
    74221 ttgaattctg ccgtttgttg cacgattctt tcaacgattg acaatgtcgt ttcaggtttg
    74281 atttttttat catcgaaata tccagtattc aggacatagc aggctgtttg ctgtttcaaa
    74341 aacaactctc gaaaagcttg atagtcttcc ctaagaggat agacacggaa aggattagca
    74401 aatggttcaa tgactagctc atctagctgt ctttttgtag tgatattttc cgcgtctgat
    74461 cgttttgttg ctaatgttgc accaaaagac gctgctaaaa ctgggtcatt gatcttgata
    74521 attggcggaa gcgaatcatc tttcatgatc caaaaaacag catcgatctt ttcgctaaga
    74581 tgatcgactc ggtcgggtgt cgcataacgt gatttgactg tccgcccatt tccgtttcgt
    74641 atatctcctg ttactaggac tttttctcct ttacttgtac atgtcacgcc cacattctga
    74701 caagtaagga aagaagaaat ggccggatca tcagacggat agtcttgtgt tttatcaaag
    74761 taagaaggtt ccaaggcagt agcaaaacca ttttttcgag aaataacgaa agcatcgtca
    74821 tgcaagatcg aaacagagtg accttccgta tgttttgcta aggtaatcgt tgattttcca
    74881 gaaccggaca acccaaatac agccatcgta taggtctggt cattactagc atattgtttc
    74941 atcccaccgt ggcaggcaat aaagccattg cgatttccca atgcccaagc aagcgtcaaa
    75001 gtcgcttttt ttaattctcc aaagtaacgt aatcctagca cagccgctgt attatggaga
    75061 gcatcaaaca aaatgagtcc atttggaaat gtttcatgtg tccattcggg atcacaaaag
    75121 atataaagat ctccctcatc aaaggaaaca gacttttgat aagtctctaa gatcttcgaa
    75181 ttcgctggct gaaaattcag caaataagaa tacaaattgt tctcaaatcc ttctggaatc
    75241 agcaaatgac tttgcacaga aaattcttca gataggccaa cgattacttt tgtatggtaa
    75301 aactggcgct tgcgactttg atacacagct tctcttaaaa ttttctcgta tttgctttgt
    75361 tccttgtcta agtcctcaaa gatccgccga gcacttgctg ttcttcccac aatgcttcca
    75421 tcattgaata ctagtgtcct aacatcagct ggtaaatcta gttcttcagc atgtgagatt
    75481 gttaaatctg tgatgatcgt tcctggactc ccttttgcta gttgataagc tgtcttccta
    75541 tcaaaaactt catgaacatt attaccgtaa aatgtcgttt ctacaatcga tcgaatactg
    75601 gataacagtg gatttccact tgtgatttcg tttaattcga gactctcttt tgtactcatg
    75661 gctcctcctc attccctaaa caaaaaaacg ttttctttat tatacattat tcgagttttt
    75721 atttgtactg ctgcgctgtg ggaagcaaac gagttatttt tcacacaaaa aaaccgagaa
    75781 cttgaataaa caagtttctc ggtttcatca ttttcctttt atcggcttag taccagccgt
    75841 ttgctaacca gaatgtttta gcagcatccc atgaaccata acgagatgtt acatattgtt
    75901 ctgctacacg ttcttgattg gcagctgaat agtcgccgtt taagtatgaa gcatctaatt
    75961 gataacggcc gatgtaacgt ccgttagtag ctgtgtatga accgcctgat tctttttgtg
    76021 cgatccattc ttttgcagag cttgaagttg gcgctgttgc agcagctggg gcagcaggag
    76081 ctacttcaac tgtttcaaca ggtgcaacgt atgtatgttc ttgcgttgct gtttcagttg
    76141 tagatgctgt attttctgtt gttttgtttt ctgttgttgc tgaagaatca tttgaagttg
    76201 ggattgttaa ttgttcacca acataaatgc ggttgatgtt tgcgatcgaa tttttttcag
    76261 caattgcatc gatcattgag ttgtctcctg caaatttttg tgagatctta gataatgaat
    76321 cacctgattt tactgtataa acttcatcag cgtgagcatt tgtagttcct acaaacattg
    76381 cagtagcacc agcagcaaaa gttgtaccta aaacaatttt cttaaatgaa ttcatattaa
    76441 actccttttt ttctccgttt tttattcttt cgacgctatt aactttatca tttagaaata
    76501 tttcataggt aaaagaaaca tgacatttaa tgacaaaata acgaattatt taatatttgt
    76561 aacatttaaa caaatatttt tttgatacaa aaccataaaa gccttgttgt ataagcaaag
    76621 taatcgtttt tctatgtttt tttatttttg aatgaaaaac gcagattctg taacattcac
    76681 tgcaataatc cataaaaaaa agcaaaaaaa tttttgattt ttatcaaatt ctcttaaaaa
    76741 aatgtaaaaa atacaaaaaa accagtaatt gttacaacaa ttactggaca aaaactttga
    76801 ataatgttaa ctattttttt attttaactt tctccgcaat aatttctggg catgttccaa
    76861 ttcgtttata acgacttctt ctgtttcttt agctaatatt tcatctaata catcaagcca
    76921 tttttccggt tcttttgttc ctagacgtcc aatagcccaa gctgctgttc ctctgatgac
    76981 agggcggaca tctgttaaac attctgaaat ctcaggcaat gccgttcgat cacctagatt
    77041 agctaaagca atcaatgcgt ttctctgcaa aggtttcttc ccacgccatg aaccagctaa
    77101 atgcccaaat tgctgtttga agtctttatt agacatcgaa agcattggct ttaattttgg
    77161 atatatttcg tctacttttg gttccatctc ttcatgaaaa tgaaaatctt ttccttgatt
    77221 gtaagggcag actaactggc agatatcaca tccataaatg acatttcgca tttttttacg
    77281 atattcttcc ggcatcatcc cttttgtctg agtttgataa gacaaacatc gctgggcatt
    77341 cattcttccg tcaccaagca atgcttttgt cggacaagca gtcacgcagc gcatacagtc
    77401 accgcaacca aattctcctg gtttatcagg ctcaaataca atattagtaa cgatctcacc
    77461 aagatagaca aatgaaccga actcttcagt gatcaacaat ccgtttcgtc caataaatcc
    77521 taaaccagct cgctgtgcta cagcgacatc gatcagttct ccagtatcta cttgcggagc
    77581 tagacgccat tcctcttctt tttgccattt ttctgctctt gtttggatga attcgatcaa
    77641 tcggttcaaa cggtctctga gtatatcatg gtaatcgatc ccccaagaag cacgagcaaa
    77701 ctgcccgcgt ttttcatccc taggcacttc ttcatggatc ctagtaggat acgcaagtgc
    77761 aatggaaatg atcgatttcg gctgatcaaa tgtcatttct ggataaagac gctcatcgat
    77821 atttggatgt tcaaagccag aagtatggcc agctgctttt tgttcttcca acgattcttt
    77881 taatgaatca aaaggttccg ccgtggtgaa cccgattttg tcaattccta atcgtttgct
    77941 ttcttgtatg atttcttctt ttaatgtcat ggtcttcctc gcttgctgtt aacggctgta
    78001 taacccataa tatagttttt cttttttcag ctggacaaac tggatctgct gatcggcaat
    78061 cttcttttct tccatccatt tttttcttgc agcaaatact tcccaataat ttgttgaaat
    78121 taattttctt ttgttatcta atgcattaaa aaaattcaat gaaactggtt ttgtacttaa
    78181 cagttcatgg agccttacct cttcccatgg cgaaaactca gacagatcgc gggaatacaa
    78241 tacttcttca tagagatttt tttgctgtgt gtacgtgaat gtttgcggga ttttcccagg
    78301 cctagcaatt tctactagac gattataaaa catattcatt aatttgctgt tggcaataaa
    78361 ttgactttta taataggccg actggatctt tttgattact ccttctgctt tgatgactga
    78421 aaataatgca ggccatgctt tgacggttat ttcgtcgttt tgtttaacta atacgccagg
    78481 tgtgaagccg actggagaaa ggaacacaaa ataaccgata ccggtatttt catctaaagg
    78541 ctgaaattca tcaaacaacc atttgcctat gtacagctct tcatctggtt ctgttgtctc
    78601 attttgattt gctatgaata atttagctaa ttctgcttca agaaattgaa ggtcttgatc
    78661 cttgtcggta ttttcctgct ggctgatcaa tcgaaagact tcttctttaa tcgtatattt
    78721 atctttacgt gtaaaattca tagccacacc ttccttcctt actctaacta taacggaatt
    78781 tcttcaaaaa aggtatctgt acgacgaaaa acagcataat tttttttcat atctcttata
    78841 aaaaatgcaa ggtctgctcc tcaagctaga ccttgcactt ttcagctttc ttttgtttgt
    78901 gacaaacctt catggatcgt ttcaatattc catttcatca tctgatagta agaatctcct
    78961 tgttctcctt cttttgctat ggaatcagtg aacagtttat catagatttt caaacccgtt
    79021 tcttttgcta cccgttccat gcttcttgag tctacactgg tttccacgaa taaaaccggt
    79081 acttcttttg ctcttatctg atcaatgatc gctttcattt gatcaggcgt accttgactt
    79141 tctgtattga tctcccatat ataagctgct ggcaaatcat atgctcgtga aaaatacttg
    79201 aatgcccctt cacttgttac taataatttt ttgttctctt cgatagaagc aaaactttcc
    79261 ttcgcttgtg tatctaattc ttttagtttt tccacatatg cttctgcatt ttttttatag
    79321 agtgtcgcat tttctgcatc tttttcagag aatatacgtg cgatttcctc cacatatttt
    79381 attccgttag ataggtctag ccaagcatgg ggatctgctt ttgtatgttc ttcaccgcta
    79441 gttaaataaa gaggttctac atttttgcta actgcaaaat aatcttttcc ttcttctttt
    79501 ttagccgttt ccatcaagtt atcgaaccag ctgttacctg tttcaagatt caaaccgttg
    79561 tataaaataa catctgcatc gcttgccttt ttgatgtctt ctggtagtac ttcatattca
    79621 tgcggatctg ttccgactgg tacgatactg tggatatcta tttgatctgt tccgacctct
    79681 tttgccatgt ccgccaagat cgaattggta gccacgactg acaacttttc tttacttcct
    79741 tcatccgctt ggtcagaagc ctgctttccg caaccggcta ataccaagaa actaactgcc
    79801 aagattaaaa agagtgattt ttttgttttc atctatctgc ttcctttctg aaataaaatt
    79861 ccttttgttg gagaaaataa aaaagcaagg ataaaaaatg cggtacatgc taacacgatc
    79921 gtagctcctg atggccaatt gtaactataa ctgaaaaaca caccgacaac tgcacttagc
    79981 ataccgattc ctgcagctgt aatgatcatt ttcagtaaat ggttcgttag caagtaagcc
    80041 gtggcggctg gtgtgatcaa catggcaatc accaagattg ttcctactgt ctgtaaactg
    80101 actacagcca ctaatgtcaa aaagaacatc aaaagataat ggatcagcga tgtgttcagc
    80161 ccataagctt ttgccattgt cggatcgaat gatgtgatct tcaattcttt ataaaagaaa
    80221 aagacaaata tcaagacgat tccactaacg agtgctgtca gcaacaaatc gctttcccta
    80281 acagctaaga cattcccaaa taaaatatga tacaaatctg tcgcactctg ggcatatgaa
    80341 atcaagataa tccctaatgc aaaaaaggag ctaaagacaa ttccaatcgc tgtatcattt
    80401 ttcaatcggc tccgctgagt cacgaaacca atcactgctg ctgttagcat cccaaaagca
    80461 gtggctccaa agatgtaact aaaaccaaac atataagaaa tggctacacc tggaagaact
    80521 gcgtgagaga tagcgtctcc catcaaagac atccctcgta aaataataaa agaaccgatg
    80581 actccagaag caagtcctac aagcatggaa gtgaccaaag cgtattgcag gaattgataa
    80641 ttcattaatc catcaataaa ggattggatc attttttctc tcctcctttt actaaatgtc
    80701 tgatgatctc accataggcc aattgaaggt tcttcgatgt aaagacttct tgtactggac
    80761 cggaagcgat cagctgttta tttaaaagaa taacctcatc gaaatattct tctactttat
    80821 gaagatcatg atggacgatc aaaatcgttt ttcctgaatt cttcaattcc tgcaagatgt
    80881 caaagatctt tcgttcactt aacgcatcaa tccctacgaa tggttcatct aaaaagatcc
    80941 attctgctcc ttgggctaga gctcttgcaa taaaaactct ctgaagctgt ccacccgata
    81001 gttcgctgat ctgtcttttg gcatattctt ccatccctac ttttttcaaa gcttgtcttg
    81061 cacgttcttt ttcttttttc ccaggtcttt gtccaattcg taaagatgga tatgttccta
    81121 aaagtacaac gcctaataca tcaattggaa aggaaagatc caattcactt cgctgttcca
    81181 cgtaggctat ttttttacgg actgagttta ccgactgtcc agaaaaggtg actttaccag
    81241 tagtagctgg tatcaactct agcaaagatt tcataaatgt tgattttcct gcaccgtttg
    81301 gtccgataat accggtaatt ttttgtggat ttatcgtcaa gttgatagtt ttcaaaacag
    81361 ttttcccttg ataagcggct gaaaggtctt gaattacaat ggccgtacgt tccaaatctt
    81421 acactccttt ttaggtttac ctaacttttt atttaaatat agtttaacta aaatggaaag
    81481 cattttcaag tagaatgatg aaaaagtttt tttcgaattt tcctcgcatt ttatgaaaat
    81541 tttctgtaga atcacatcaa gagttcaata aggctaacct aataatgaaa aacatgtgtt
    81601 gaaacgtttg attatttttt cttgttgact caacaacgaa aggagttttt gtatggaaga
    81661 agaaaagtta actcgaagtc ttagtgcccg tcatatccaa atgatcgcac taggtggaac
    81721 gatcggtgtc ggtctgttta tgggtgcctc ctcaaccata cgttggacag ggccctcagt
    81781 gatgggagcc tatgcgattg caggattctt tttgtatttg attatgcgtg ctttaggcga
    81841 aatgctttac gttgatcctt cgactggttc ttttgcaaat tacgcgagcg agtacatcca
    81901 tcctgtggct ggctacttga ccgcttggag taatattttt caatatattg tcgtaggaat
    81961 aagtgaagtg attgctgtag gatcttatat gaattattgg tggcctgatt tgccggcaat
    82021 tattcccgga atcattgtcg tcttgtttct tatgctggca aatcttattt ctgtcaaggc
    82081 gtttggcgaa ttagaatttt ggttttcgat catcaaagtc ataacgatca ttttgatgat
    82141 cattgcaggt cttggggtaa tcttatttgg atttggtaat catggtcagg cagtagggat
    82201 ttcaaatctt tggaaaaatg gtggattctt cactggaggc gtcaaaggat ttttctttgc
    82261 attatcgatc gttgttgctt cctatcaagg aatcgaactg atcggaatga ctgctggtga
    82321 agcagagaat cctaaaaaga cgatcattga agctgtccag tccactatcg gtcgaatctt
    82381 gattttttat attggtgcta tttttatcat tgtgagtatc tatccgtgga atcaattgag
    82441 tgagattggt tcaccttttg tacaaacttt ttctaaagtc ggcattacat ttgctgcagg
    82501 actgattaat tttgtcgtga ttacagcggc attatcaggt tgcaattcag ggattttcag
    82561 cgcaagtcgt atggtctata cacttgccat aaatggaaag atgtctaaaa aatttctgaa
    82621 actatctcgt cacggtgcgc ctttttatcc tgtcgtagca atctcaggtg gaatcttaat
    82681 tggtctgatc ttaaattatc ttctaccaat gttcatcaac cagtcagaaa atattttcgt
    82741 tttcgtatac agctcaagta ttttgcctgg tatggttcct tgggtagtga ttttgatcag
    82801 cgagattcgc ttcaaaaaga agcacgcaga taaaatgcat gatcatcctt ttaaaatgcc
    82861 actatctcct tatacgaatt atgtgacact tgctttttta gctatcgtat tgattttcat
    82921 gtttatcaat cctgaaacga gaatctcatt gattattgga ctcgttttct tgctttacat
    82981 gacgatccat tactttgtac gcgaaaaaag aaccggaaaa taaaaaaaga acgaagcttc
    83041 accttagtgg aagcttcgtt cttttttatt gcttttatca attcaatttt agcgtctcac
    83101 cgggagtcag gaaataattc tccatgctca tcccattcag cgacaagatc gtttctactg
    83161 gtacgccagt tcgttcggct atttgatttg gaccttctcc ttccaaaact acggttgtcg
    83221 cagcctgtga agtcgcgctg ttggtattag tttcagagga atctgttgtg tcttgtgttg
    83281 ttcgagcttg catttcagaa gcttctaccg actctgctgt ctcagaatca gaagatgttg
    83341 tgtcttgtgt gcttgttgac tctgcttgaa gagaggcgct agtctgcaaa taaatatcgg
    83401 aaatcttagc gacatgattc gtataattag ccgataattg attgatcaaa gtatctaagt
    83461 ctacaccgtc tttattttct gctgcctgat acgctgcacg taattttctg atcccttcgt
    83521 cggagattgc ttgaagctca cgtgcttttt ggttagcaac tgctgataaa ccagctattc
    83581 cctcttgatt tccctgaatt tctgtctggt attcttcaat caatgcaggc gtcttttctt
    83641 cgatcttttt cgaataatca tttacgattg cttgaagttg ctctggcaaa ccatttgctg
    83701 ttttttcttc agaagtttgt gtctcttttg ttttagttga tgactcactt gtttgtttcg
    83761 tctctgtttt ctttgtcgtt gtttccgtta tggtcgtact tttcgcttct gacgaatttt
    83821 ttccatgaaa atatagaccc gcaactcctc ctgctatgat caaaaacacg gcaactgctg
    83881 ccccaatcat gatcatccgc ttacgagctg cctgtttttg ctgtcttctt cgggtcatcc
    83941 gaacattttc tccccactca ttttcatcat acattttttt caccaccaat ttttatgtat
    84001 aatagcgtta tcaaacgctt catattctta ttgtagcaaa taattgtcgc tgtgcacatt
    84061 tttatctttg ttatttataa gaaaatttca ccagttgaga tgattccaag attgtccgtc
    84121 gatttctcct tgcagctgca ttgttcgttc gtctatctca gccatcagtt tctttatttc
    84181 atataagagc gcacggtctt gatattctga tttttcgctt aattcatcta attgttggat
    84241 cagccaatca tttgtcataa tgaagttcct ttcatttctt gcagtgtaaa ggtcaagtct
    84301 tcgatctgct cttttgcctc agtcagtgct tctacgatat atgcttgttt ttcagattct
    84361 tcttcctgca ttttctgatt ttcctgtact ctttgaataa accagtcaat ccgctgagtc
    84421 agcgatggtt tgccttccaa tgagagatac tgctgataag caattagctt ctcccaacgt
    84481 ttttcctggg ataaatacat aaattgtgct aaaacgaatg gcggaagata ggtcatatgg
    84541 aatttatttg cgattcgctg atacggcctc aaaaattcgg aaatcgtata ttcttctttt
    84601 cctccagctt ggtattcttt ttccgccaca cctgttgtca atacgattcc tagttctttc
    84661 ccttttaata catgtgctgc tcgttccaag acattatctt gccaaatttt taaatgagca
    84721 ggagaactat accagtaaaa cggaaactgg aaaatgatcc gatcatgctg ggccaagagc
    84781 tgtagttcag tctctatatc tatttttccg tctggataac ttgattccaa atgatgccaa
    84841 gtagctggta aaccagcaga agcttctttg aaaaattgct gatttaaaga ttcttcgatc
    84901 gttggatggc taatgatgat aagtgtacgc atcccttttc ctccttttta gtcttcgctt
    84961 tacagtgtag cataaccgcc acaagtttct tttgccgatg cttgtcattt taaccagact
    85021 aatcaggttg tccaagaaac tgcggtttgt ttttccaact gttttttcaa ggtatccaaa
    85081 gcaatattct taaaattttc gtttttcata cgtttacgat agttcgtagc cgtttctccg
    85141 gtactctttt tgaacattcg gctaaatacg actagactat tgaaccctac ttgataggca
    85201 atactttcca cggattcatc cgtcagagaa agaagaaacg cccctcgatt gatccgtacc
    85261 ccgatcaaat attccttgat actggtaccc atatgatttt tgaatactcg cgacaaatgg
    85321 ctccgattga ccgctaaatg ctgggcgatt tcctcaacag acaatttttc agcataatgt
    85381 gcctcgatgt atttgactgt ttcaacagct aaagaggaat gaaccttttg tacaccaccg
    85441 ctgacctttc cgccatcttt taaaaggact gataaaaaac ggtaggttaa tgctgttaac
    85501 tgtaattcat tttccaaggt ttcttccgta tctttcatgc attctaaaat aatgtcgata
    85561 tatttttgta tgtcagaaga gaccatcgtg tattggtctt ctctgaaaag cgactgccga
    85621 atgatttctt ctgcagcact cccaccaaat gaaagccagc aatacatcca cggatcttct
    85681 ccatctgata agtaaaacgt cgagtctcct ggacgaatca agaacagatc accttttttc
    85741 aattggaatt gttgattttt cacatgataa gatcctttgc cttccatcac gacatgcagg
    85801 atgtaatcat tgcgaatagc aggaccaaaa gaatgaaacg gcatcgtttt agagaaacca
    85861 caaaaatcaa aatacaattc tttttctact tgttgatgtt ccttttttaa aaaaatcgat
    85921 tgctccacgt ctatccctcc ttactccttt agtataatgc aacaaaaagt taaataaaag
    85981 tcacagaaat atattaaaaa ggaagcgatt tcttgttaag tttaagtcat taaaagatct
    86041 ttgttattcg ttgtaaccgg tttacttagt attatatatt gaacaggaga ggaatacaga
    86101 ttatgaaaag caaaatgatc caacgtgtgt cctacgcttt aggcgctttt ggacacgaca
    86161 cattctatgt tacattaagc acttatttta tggtattcgt gacaagccag atgttcgcag
    86221 gaacagataa ggcaacgaat gcaaaaatga ttgctacagt tacaagctta gttgtaggta
    86281 tccgcttagt tgaaattatt tttgatcctt tgattggtgg catcatcgat aatactcgta
    86341 caaaatacgg taaattcaaa ccatggttag ttatcggcgg cgttgttagt tccgtactct
    86401 tggtagcaat ctttaccaat ttctttggct tagctactca taatacgact ttatttatca
    86461 tattatttgc aatcgttttc atcttattgg atagttttta ttcatttaag gatatcgctt
    86521 tttggtcaat gattccagct ttgagtacgg aaacaaagga acgtgaaaaa tttgctacgt
    86581 ttgctcgttt cggctcttct ctaggtgcaa atggtactac tctagtcgtt gtccctatcg
    86641 ttactttctt tacctatctt gttactcata aacatattga aggcgcttca ggctggttct
    86701 ggttcggtgt gattgctgct gttatttcag gcggtactgc gattatcact gccttgggca
    86761 caaaagaagt cgatactgcg atccgtcagc aaaatgaaaa agctgggatc aaagatgtgt
    86821 tcaaagcagt tgctcaaaat gatcagttga tgtggcttgc ccttgcttat atcgcttatg
    86881 cgattgccaa tgcagcaaca actgccgtat tattctactt cttcaaatat gtacttggcc
    86941 aaccaactga attttggatc gttggtctag ttgctgcctt acttggttta gtagctgttc
    87001 cactattccc aatgcttaca cgcgtcatct ctcgtcgcta cgtttacctt ggagggatcg
    87061 caatgatgat ttcttcttac tttttcttta cgatcgcagg ttcaagtttg ccaatcgtta
    87121 tcatcgggct agtattgttc tacttccctc aacaattgat tttcttatcc gctttgatga
    87181 cgatcacaga ctctgttgaa tatggtcaat ggaaaaatgg tatccgtaac gaagctgtta
    87241 ctctatcaat tcgcccttta ctagataaaa tcgctggtgc tttgtctaac gggatcgtag
    87301 ggtttgtcgc tatcgcttct gggatgactg gtaatgctac tgctgctgat atcactgctc
    87361 atggcgtaac gactttcaaa gcttatgcat tctatgctcc tgctgctttg atgattttct
    87421 ccgctattat ttttgcttgg aagattacat tgacagagaa aaaacatgca caaatcgttg
    87481 agaaattgga aaacaaattg gctccagctg atacaatgga agatgaactt cacgatgcag
    87541 tagatccttc ccattaagaa aggatcttga aaatgaagat tacagaaaaa gattttggcc
    87601 aaggttatca cttgataacc ttggagaaca aaaacaagct agcactttct atctctgatt
    87661 taggtgctag aatcgtcagt ttaaaatcaa atgatcgaga attagttttg ggatttgaca
    87721 ccgctgaaga atatatcgaa aaagatccgt atatcggtgc ttctatcggt cgcaccgcag
    87781 ggagaatcga aaatggccgc ttttctctca atggaaaaac ttaccaatta gccacagatc
    87841 caaaaactgg acataatctg catggtggtg ctcctggatt tgaattaaaa aaatggtctt
    87901 atgtcatttt gaatggcgaa aatgaagctt ctgtcatttt tactactaca agtcccgacg
    87961 gagaacatgg ttttccaggt acaatggatg tggaaatccg ctatactttg acaaaagata
    88021 atatctggcg agtgacctct cgcggcacca gtgaccaaga tactttattc aatccgacaa
    88081 atcatgttta cttcaacttg acgggagatg cttctcagtc aatcgatcaa catgagcttt
    88141 ggctcaatag cgaagcttat gctcctttgc gaacagatag tattcctata ggggtaaaag
    88201 aaaatgctgc aggaagtgct ttcgattttc aaatacctaa aaaattagcg tccgtttttg
    88261 ctagtgattt ggatcaaaaa aatcttgttg acggaatcga tcatccattt ttcttaaaag
    88321 aaaccggctt gggtaaagaa gccgctcgct tgactagccc cgataaaaga atccaagtag
    88381 atattgctac agatgcttct agtgtggtta ttttcactgc aaatttcggc acagaaacac
    88441 cagaaatgcg caaccgaaaa ctggcacatc acggtggcat cacatttgag actcaaacag
    88501 ctccaggtgc agagcgcttc tcagcatttg gttcgattca tttaaaagcc ggatcagtat
    88561 ttgaaacagt aacagaattc aaaatcaaaa caagaaagga ataactcatc atggaaatca
    88621 aaagaagctt aaacacaaaa tttgccgaaa cattcggacc taaaaaaact acacaatact
    88681 tctcaccagg acgcatcaat ttgattggtg aacacacaga ttacaatgga ggccatgtct
    88741 tccccgcttc catcacttat ggaacgcaag gtgtagcagc acctcgagac gataataaaa
    88801 tattagttta ttccacaaac tttgacgata tcggtgtcat tagttttact ttagatgagc
    88861 tagaatatga taaaaaagca aactgggcaa attacgtaaa aggaatggtc cttaaattaa
    88921 aagaagctgg acactcaatc gatcatgggt ttgagttatt agtggaagga acaatcccta
    88981 atggtgcagg actttccagt agcgcttcat tagaattatt agtaggtgtt gtattagaag
    89041 atctgtttga tttaaaaaca gatcgcttgg aactagtcca aacaggtaaa aaagtagaaa
    89101 atgaattcat cggtgtcaat tcaggtatca tggatcagtt tgccatcggc ttcggtgagc
    89161 tagatcatgc aatcttatta gatacaaata cgctgaaata cgaaatggtt ccagtgaaac
    89221 tagatggtta tgcaatcgtc atcatgaata cgaataagcg gcgggaattg gcagattcaa
    89281 aatacaatga acgccgtagc gaatgcgaag aagccttggc acgtttgcaa aaaactttgc
    89341 ctatctcttc tttaggagac ttagatgaag aagaatttga atcaactatt gaccaaatcg
    89401 gcgatgatac attgatacgc agagctcgcc atgccgtttc tgaaaatcag cggactttga
    89461 aggcaaaagc tgaattagaa gctgggaact tagaagcatt tggtcaactg ttaaatgatt
    89521 ctcaccactc tcttcgctat gattatgaag taactgggat cgaattagat acactagtag
    89581 atgctgctca aaaacaagaa ggtgtcttag gtgcacgaat gacaggagct ggatttggtg
    89641 gctgtgcgat tgctcttgtc aaagaagaaa atatacctgc cttcaaaaac aatgtctatg
    89701 atgaatacat gaaagttgtc ggctatgctc cggaatttta tgttgcacac attggaaatg
    89761 ggacaacaaa gatcgatcca gaagctgttc atgtttgata aaaaaatcaa cgatctcagc
    89821 taaaaacaaa tagataaaaa taacctctca gcaatttcca aatgtgagcc ttttgctcgt
    89881 atttgaaaat tgctgttttt tattgacacg gaaagagaac gtgtgttcta attgtgttga
    89941 agaggtgatt gttatgtggg cgaatcaaaa tccggtattt gtttatgaaa aagaaccttc
    90001 aagagatatt ttatgtattg actgcaaatc tttttacgcc tccgtagagt gcgttgaaaa
    90061 ggatcttgat ccccttacaa ctaaattagt agtcatgtcc tatccgtccg attcgacaga
    90121 aacacggggt agcggattaa tcttggcttc cagtcctgca gcaaaaaaag cttacggcat
    90181 caccaatatc agccgtgcca gagatcttcc cttcccctat ccaagtgatt tatatattgt
    90241 tgccccaagg atggcctatt atatggaaaa gaacagagaa atcaattcta tctataaaaa
    90301 atatgcagac gaagcgaacc atcatgtcta ttccgtcgat gaaagcttcc ttgatgtaac
    90361 aaatagcatg gcactctttg gtaaaacaaa tgcgtacgac atggctaaac tgatccataa
    90421 agatgtgttt gagcagaccg gaatctacac gactatagga attggcgata acccgctact
    90481 tgctaaacta gccttagaca atggctcaaa agacggaaag caaatgtttg ctgaatggcg
    90541 ttatgaagat gtaccagaaa agttatggaa aatctcagat atcactgact tttggggaat
    90601 cggcaaacga acagcaaaac gtctgaaaca aatgggtata cattctgttt atgatttagc
    90661 tcacgcggat tattatcact tgaaaagcaa gctaggggtc atcggtactc agctttatgc
    90721 ccatgcttgg ggcatcgatc gaagtttttt gggacaagaa tatacaccaa aatcaaaaag
    90781 tatcggaaat agtcaaatcc tagatagaga ttatacaaga cgagaagaaa tcgagatcgt
    90841 tatcaaagaa atggccgacc aagtcggcac tcgcttgaga cgatctgcag caaaaacaca
    90901 agtagtcagc ttatgggtag gatactcttt aggctatctt gatccaaatg gcaagaccgg
    90961 gtttcaccag caaatgaaaa tcgaagcgac aaatgctagc agagatctag cagatgcttt
    91021 attgaccatt ttccaccagc attaccacta ccaggatatt cggcgtgtag gcgtgaactg
    91081 ttccgacctc gtatacgcga caggtttaca gcttaacctt tttgaagatc ctgaaaagca
    91141 gataaatgaa gcgaaagttg attttgttgt cgatacgatt agaaaaaaat acggctttca
    91201 atcaatcatc catgcgcata gtctcttgca aggaggacgc gccatcgcac gtagttctct
    91261 cgttggcggg catgcaggtg gtatgagtgg attagaaggt ggaaaagatg agacggacag
    91321 caaaaaaatt cattgactat aacgagtatc gagatcggcc atttggatta aaatggggga
    91381 ctgcttttgc gatggaagaa ctagtcaacg gtatcaaaaa aatgaagaag aagcacgcaa
    91441 acagcctctt cctaaacaac aaatgacatt gcaagaaatc gatagtatac tgacagaagc
    91501 ctttttatct cgtaaagcag taatcattca gctcaattta aaagatgaat ttggaagact
    91561 cttggatgag gtcgaagggc acttcattgg tgaagcctat gaagattact ttatgattga
    91621 ccatcagccg atattgtggg aagacgtacg gtatattgag ttaaaggaaa caaaaaaatg
    91681 gtttgtgaca tgagaggttg tgacagaagt gatcaacttc aaaaaataag aaaggatttt
    91741 tcgaaaattg cttcttaaat ttttgtggaa ttttggctta tttttcgaag aagcaacttc
    91801 tggaacaacg tatattagat atcagaggtt gtgaaaaagt cgcttagttt tgagtaacaa
    91861 gccaaggcgc tgatttcaca acctctgtct atctatccat ctattcggta agattcatgc
    91921 atgacgtctt ctttatttag tatgtagagc cctttttctt ctgaccattc aacataaatc
    91981 agctgtttta catctgcata gccttctttc ttcaagttct ccataagcca tgcttcagtc
    92041 aattgattgg actgaagcac tttatgctga atttgccctt catctacaag caggatcgat
    92101 aaagctttgt cttcatctga ttttttcaat acactcattt gaccggcatt ctctaggata
    92161 acatgtttgg cattttcaag aaaaaagcat tcttgctgtc ttaagattgc tcgcaactgc
    92221 tccatctcga tatggttatt tgtcaactct gtcatgttga tgacgccgtc tttgattaga
    92281 acagatggct cgcctttgac ccaacgattg accttttcat ttttttggac gatacgttcg
    92341 ataccataaa tcattactgc ccaaagcgca atggcaaata ggacatgccc tacatggaca
    92401 ttgtcatcat aggttgattc ttctaagatc ccacctaaaa caagcgtata gactaaatca
    92461 aacggtgtga tttctgacat ggatttcttc ccaagcaaac gtaccactaa taataaaccg
    92521 atcaacccga acaccagttt cattgtaatt gaaaaaatca ttttttctcc ccctaactat
    92581 ctgttaatta aattatatat gctttctcac gaacacgcat ggaatataca aggaagaaat
    92641 gtatcctttt actaaaaaaa ggactgtgac actgtagtga cccccaaaag ttagactttt
    92701 ttggagtgga gaaatccact cctttttttt atgctctaaa atgatatttt tacacaaccg
    92761 ttacggttgt tttacgaaat tggacgagac tttgccagtt taatttctgt tttatccgtt
    92821 cattattgta gtaatagata tagctatcga tggctgattt taattcctcg aaacagttat
    92881 aaactttccc gtgaaaaatc tcttgtttta ataagccaaa aaaattctcc ataagtgaat
    92941 tatctaagca gttccctttc cgagacatgc tttgaaagat tttgtactcc ttcaatttgt
    93001 ttctataagc tttcatttga tacgcccaac cttgatctga gtgaaacgta cgacgatagg
    93061 gacaatcgtt agtggtctgg atagcttcct ccaaaccttc cattaccgct aatgcattgg
    93121 gcttttcaga gatacgatag gataaaatct cactattgaa catatccata aaaggatcta
    93181 gatacaattt cttttgacgg ataatgcctt tggcatccac ttcatggtat ttaaattcag
    93241 ttgtatccgt cgtgattttc tgatggcaga tactggtgta gaaacgacga tggatccgat
    93301 ttttggctac tgctccaact tttcctcgat aagaattgta gcgacgtgat ttacgcgtgt
    93361 atgccgttac ttttattcct agcttcttga tcaagcgctg aactttcttt ttattgatag
    93421 agaaaccgcg gtttcttagt tcattggtca tccgtaaaca gccataatcc ttgtgcttct
    93481 cccgaatttt aagcatttcc gcttcaatct cttgatctgg atttttacgg tccaatcgcc
    93541 tttgccatcc aaataatcat gaacgatctt taatttaagt tcaaaagtat atttaaccat
    93601 aaaaaatacc gacctccaaa agttagattt tttggtctaa cttttggggg tcggtacaca
    93661 aatcgtgtca cagtcccttt tttgaaaata aacggtgttc aaaagcttgc atctgcggta
    93721 ataagtccag ccaagttaaa aacataagaa gctgttttta cttggctgtt cttattactt
    93781 gatgcaaggc agctttttca caacctcttt tcaaatattt cgttttctta ttctacaaat
    93841 ggttcttctc ctaacgcttg ttgagcggct agattcaaca tgctccattg tcggtcaaag
    93901 cctggctgga agaagaagtc agcttctgct agttcttcta aagtcagttt gttttggatc
    93961 gctagtgcca atacatttcc ttgacctgta acatcatagg tagataatac tgctcctcct
    94021 agcaattgat gggtcattgg atccgagaat aattggatgg acacttttgg atttccttgt
    94081 tcttctggta catattttgg tcgtaacgta tcttcataat aagacactcg tacatctact
    94141 cctgcttttg ctgctgtaaa gctattcaat ccgcttgctg caaaatgata gtcaaagaca
    94201 cttaatgcag aggaacctac gactccgccg aacggtttgt ttggtacttc ttcaaaaaga
    94261 tgttttacta cataacgtgc ttctctacgt gcaacagtcg ctaaagcgat cggcattttt
    94321 ttgcgtgctg ggatagaata agcaagtgta gcatctccta ctgcatacac atctggaaga
    94381 ttcgtttgca agtattcatt tgtttggatc cagccacgtt catctaagtc gacgatccct
    94441 tttaaccatt ctgtatttgc cttcacaccg gcagcttgaa tgactagatc tgctgggatt
    94501 tctttttcac ttgttttgat tgcctcaact tttccgttac cagtaaaagc ttcgattttt
    94561 gcatttgtca aaacttcaat accgttttca tttaggtgtt gttctaaaat atctgtcatc
    94621 tcagcatcta aataagtgcc taaaggtcta tcgatcacat caagcaatac gacttctttc
    94681 ccagcttttc ggcttgcttc tgctgcttcg atcccaatgt aacccgcacc tacgacagcg
    94741 atttttttaa tagccggatc atttaatttt tctttgattt tggttgccca attgtatcca
    94801 cgcatcaagt agacattttc tagatctgct cctggtactg gcagattgtt tggtttgaca
    94861 ccagaactca aaatcaattt gtcataagga tattcttttg tttcgttatc tgatgcgcta
    94921 gtaaccgtta ctgttttttt atcggcatcg atcgttttta cttcgtgatt atttaaaata
    94981 tgaacattgg attgcggaaa gttttctggt ctgaaattac gtacatcatt tacatctgtt
    95041 accttgtctt ctaaatacag ctccatacca catgacatga aggaaatata gtctcctgct
    95101 tcaaatagcg tgatatctac attttcaccg tatcgtgtca atagttccaa gatcgattga
    95161 tgccctccat gagatgcacc tacaatgaca actttgattt tttccattga tgaaacctcc
    95221 ttgaatattc ttttaaaatc attctaaaca atttaaactt aacattacat tagttatgaa
    95281 tcaaaagaaa cgcgttcatt tgaactaaat ttaaaaaaca atcgtctcct tgcagaatat
    95341 accgcaaaat taacgattgt ttttttgata aaatctatga atcactgttc tgttaaaaag
    95401 tctttgatcc gtttgcaggc ctcatgtaat ttttccatgc tgctagcata agaaatccgg
    95461 atataacctt ctccttctgg gccaaatgca attcctggga tacacgcaac ttttgcctgt
    95521 tccgctaatt ctacacaaaa ctgccaagag tcagtttgaa tggcagctgg gagtttgcaa
    95581 aacaagtaaa atgcaccgtt tggctgggtc acttcaaatc ctaaaggcgc caattgctgg
    95641 accagatagt ctcttcgtgt ttgatattgc tctttcatat tctcgctatc tttcacccca
    95701 tttattagcg cttcagccgc agctttttgc gacatcgttg tagcggcagt caccagatat
    95761 tgatggactt taattagttc gtcaataagg gctttttgag caaaaataaa gcccactcgc
    95821 caaccagtca tcgcatgtga cttggataac ccgcttatca cgattgtttg ttctggaaga
    95881 taagtagcta tggacatatg cgttccacta taagtcaatt cagcatatac ttcatcactt
    95941 ataacaaata ccggatattt ttttaaaacc tcagcgattg ctttcaattg ttttgcagac
    96001 aatgtcgtcc cagtaggatt gttaggatag tttaaaatga ctgctttgac agctgatcca
    96061 tattgttcaa atgctcgttc aaattgttcc ggctgacaga caaaccctgt gtcagaagta
    96121 tctatcggga tcaattcagc accagctagt tccactaatg gctgatatcc tgaataagca
    96181 ggcgctggaa taagaacctt gtctccttct tccaaaacag ataacaacgc agaggcaatc
    96241 gcttccgttg caccaactgt cgtcaaaact tccgtttgcg gatcataagt taatccataa
    96301 cgctgttgct gaaatataca agccgcttcc cgcagttcct ctaatcctct cattccggta
    96361 tagtgagaaa agtcttcttc aatcgctgct attcctgctt gcttgacatg ttcaggagtt
    96421 ggaaaatccg gttctcccag ggtgagtttg atcacatctg gtatcgacga tatttgctga
    96481 tcgaattgtc gtatttttga tacttctatt ctagaaagcc taggactaaa tcgattggat
    96541 aaattcatca ttatttactc gctcctcttt tgaactgcta tcgattttta caagaagatt
    96601 ttctgtaaaa agaatcgttt tgtaccattc tacaccattt tctaaaacat ccatatcaaa
    96661 atcgaacgtc ggatcatgta aagcaggggt atcaccgaca cctaaaaaga aaaatacaca
    96721 tggatattgt tgcgtatata tgccaaaatc ttcggcttga agaactggag catctaattc
    96781 atgtagtttg tttgaatcta acagtgctgc atataagcct ctatggttga ttacagctgg
    96841 atagccgtca ttatagcgaa aagaaatagt agctgtagag tgaaactgtt ctgctaaatg
    96901 gtctaatccc ctcttcaaat aattttgcat atctgaactg taagaacgga tacttccgga
    96961 tacaataact tctccagcta aaacatttcg gatcgttcca ccttggattt ggccaaattt
    97021 cattagatga ttccactctg ccggtaattg ccggtcaaaa tcataaacat tcttcaaaaa
    97081 tcgtacagct gcctccagac tatcgattcc tttttcacta gaagcaatat gtgcagactg
    97141 gcctttaatg ataatgtctg tttcactgct ttgtgccatc aaaggtcctg gtcgagagaa
    97201 aacttctccc ttagctagtc caggccatag atgaaagcca aatattgctt gtacttcata
    97261 tttatccaac aatcctgact gaataacgct ttgtgcgcca ccggaaattt cttctgatgg
    97321 ctgatagatc agtactacat tataaataag atcctcaatg tgtttagtta taaagtcagt
    97381 caaccctaaa agcatcgcca tatgtccgtc atgaccacat gcatgcatat aaccttcatg
    97441 cttagaagca aaagagagat tcgtttcttc tttgactggc agtgcatcga tatctgttcg
    97501 aaaagcaatc gtttcttctt gctgattatc aaaataaagg agtagtcctg tttcgccgat
    97561 ttcatggata acggcctcgc tgttttttac ttgttcatat aaatattttt ttgtcttgaa
    97621 ttcatgaaac ccgatttcag gaatttgatg gagtgccatt cgatattctt tcagcatccg
    97681 tattcaccat cccttcatag atacccttca ctactgtttc atattgatta ttcggtacac
    97741 cgatgatcag attcaactcc tgtgctcctt gtgataagat cgatgtgcga atttctaatt
    97801 tgttcaatat cgataacact ttcccagata atccaatcaa ttctttatgc ggacccccaa
    97861 cgacagagat caaagctaag tcttcgatca cgacgatttc ttccacgcca agtgtttctt
    97921 ttaattcttt cgtgatgaga aataacttat cggcaatcgc ttctgctgag acgatcactc
    97981 cgatattgtc gatccctgaa ggaatatgtt cgattgatat ctcatgttta gcaaaaatgc
    98041 tcattgcttt ccagataaac ccgatttcat cggacatatg acgtttgaat aaagtgatgg
    98101 aaagaaaatc cttgcgtcca gctattcctg tcagtccatt ttccttttct atttcgtgat
    98161 tcgatatttt tgtcccttga gcgaaaggat cattggtatt ttttatttgg atggggatat
    98221 cagcctcttg aactgggaaa acagctgctt catgaagaac gttagccccc atataagcca
    98281 tctctctcag ttctctaaaa gagatttcct cgatgatttt aggatgatcg atgattcgcg
    98341 gatcagccat catgattcct gaaacatccg tccaattctc ataactttcc gcttgcaaca
    98401 tcttcgccag tatcgcgccg gtaatgtcgc ttcccccacg gcccaataat ttttcttttc
    98461 ctgcagggtt cgccccgtaa aaccctggaa caaccatttt cggatatctt ttaaatgctt
    98521 ttgtgatttc ctgtgctgtt ttttcctgat cgattttccc atcatagtca aagaaaatca
    98581 ggtcttttgc gtcaataaac tggtaaccaa gatactcagc catcagttga gcagtcagat
    98641 attcacctct acttactaaa taatcttcag ttatcttttc gtcttccagt tgtttctgta
    98701 tgcgtgctag ttcatcttca ataggtaact gcagggcaag aacatctctt acttgaatga
    98761 aacgatcaca aatccttttc caaaggggtg tccaatcaac atgatgctga aggtaagcat
    98821 aaatcaaata aagtaagtct gttactttgt catcatctga cgtacgtttg cctaaagcag
    98881 aaacaacgat cacttggcga ttgggatctg aaagaacaat tgtacggact tttttgaatt
    98941 gctcttcatg agacatcgat gttccgccga atttcgctac tttcagcgta ttactcatct
    99001 tgccacctcc gctattttct gcattaaagc tgcagcaatc tgtacggcat tcgcagcggc
    99061 tcctttgcgt atgttatcgg cagtcgtata gaacaacaat ccgttctcta aagaagtgtc
    99121 ttttctgatc ctcccaacat aaaccatatc tgttcctcta gcaagaatgc tcgtcggata
    99181 tttatgtgct gctagatcat cttctaattg aatccctgga aactggctga gacactctct
    99241 aatttcttcc gtcgtaaact ctttttgcag ttgaactgcc acagagactc catgtccatt
    99301 ttcgattggc acacgtacgc aggttgctga tactggcaaa gcaggctgat gcagaatctt
    99361 acgggtctca tttatcattt tctgttcttc ttttgtatac ccattttcca aaggctgatc
    99421 gatttccgga atcaccgttt ggctaatatt ataaggatac aaaactggtt cctcgtcatt
    99481 ttgcgtacga tgaagatctt caatgccttt ttgcccggaa ccagaaactg cttgataggt
    99541 cgaataattg actcgctgga taccaaaggc ttcttgtaaa gctttaagcg gaagtaccgc
    99601 ttgaatggtt gaacaatttg gatttgcaat cagccgattc aatgtatagt cttccagatt
    99661 gacctctgga acgattaatg gaatatccga atcttcccgc catgctgagg aattatctat
    99721 gacaaatagt ccctgacttc gtgcgattgg cgcaaactct ttggatacag aagcacctgc
    99781 agaaaatagc gctaaatcat atccttcaaa tgaagtttct gtcaattcct gtacagtgtg
    99841 tttctttttc ttgaatacac aaactttacc ggctgaacgt tttgaagcta ataatttcaa
    99901 tcgtcctact ggaaaatcat attcttctaa cactttgagc atcgtttggc cgactaatcc
    99961 ggttgccccc acaatacagg tatctatttc gcgcattttt ctccatctcc tctataattc
   100021 gcgtaacgca gcaatcaatg ctgtattttc ttttgtctga tcatcactta tttttaatac
   100081 acgtgcaggt attccaccga caacagtttc tgctgccaca tcttctaaaa ccactgctcc
   100141 tgctgccacg actgcatctt ttccgatatg gacaccttca acaatcactg cattcgcacc
   100201 taccagtacg ccgtcttcta cgataaccgg tttggccgat gctggttcga tcacacctgc
   100261 taagacagct cctgcaccaa tatggcagtt tttgcccact gtcgctcgtc cacctaagac
   100321 agcacccata tcaatcatcg tgttttcacc gattactgca ccaatattga taatcgctcc
   100381 catcatgatc acggcattgt tgccgattga cacttgatct ctgataatag cacctggttc
   100441 gatacgagca ttaatttttt taatatctag caaaggaact gcgctgtatc ttgcagcagt
   100501 ttcgatttcg atttcaatga ttttttctga ttcagcttct aaaaccggag caatcgtctc
   100561 atagtcacca aaaacaacga agctgcttcc ttcaccaaaa actttacttt ctttaaattc
   100621 gattggctcg gttacattca gatagacttt cacaggcgtc tttttagatg ccgtttgaat
   100681 gtagcggatg atttcttgag cttccacgtt ttttacaccc ctttgtccat taataaatct
   100741 tctaatttgt aataacctgg tgactgatct ttcaaccagt ccgctgcttc tactgcgcct
   100801 gcagcaaaga ttcgattaga aaaagattca tgtttgatcg taaatatttc atcagtagca
   100861 gcaaacaata catcatgttc accaggtaaa gaacctgcac gaatactgtg tacaccaatt
   100921 tggttttctt ctcttttttt cccttgccag ttgtatacgg gctgcagctt ttgcacttct
   100981 tggattgttt gaagcagcat atttgcagta ccagatggtg catctttttt acgactatga
   101041 tgtttttcaa tcagttcgat ctgccagcct tgcaacattg cagctgcttg cttgattagt
   101101 tgattcatca ccatgatgcc gaacgaaaaa ttagcactat acatcacagg tacatgtttg
   101161 gcatgttctt ttatttcttg gaactgtgat tgtgtataac ctgtcgtgcc aatgactaac
   101221 ggaagttgat atgataagct atacgaaagg attttctcta aattatctgg atgagaaaaa
   101281 tcaataagca gttctggcag ttccgtaaaa gcaagcgtag ttgcttcttt aggtgccgtc
   101341 cgtaaaagaa ggaccgtatc tcctctttct tgtgcaactt cttcgactct atttcccatc
   101401 tgtccactgc caatcagtcc gattttcatt tttcaaccgt cctttctttt aacaaaagct
   101461 gagctaattg tttctttttc tcttttgaaa gagaaactaa aggcaggcgt agaggtccgg
   101521 aaggtaagtc taataatgac atggctgctt tgacaggaat aggattggtc tcactgaaca
   101581 aggcatggat cagttcaagt gcatttaatt gcttttcttt tgcttgctgc catcttccgt
   101641 cctgcgtatc ttttactaat tcatggacta ttttaggttg gatattcgcc catacactta
   101701 ttacaccgct tcctcctaca ctcattactg gtaggatcaa atcatcattt ccactgtaaa
   101761 ggaagaattc ttctccaatc aaccgagcgg catccatcac ataagccata tctcctgagg
   101821 cttctttcaa accaatgata ttaggatgtt ctgctaaatt tactaataca tggattggaa
   101881 tcgacatgcc tgttctagaa ggaacattat acaaaataag cggaatcggt gaggcttctg
   101941 caattgctgt aaaatgagca gctagtcctg catcacttgt tttgttgtag taaggggtga
   102001 tgaccaaaag tgcgtctgcc cccaaagaag caaaatgctt cgctttttca atcgtttctt
   102061 tcgtattatt cgttccagct cctgcaatca ccggcacacg gccagccact ttctttactg
   102121 tcagttgaag gatctgctcc tcctcagatt gtgtgagcgt agaagattct cctgttgtac
   102181 ctaaaactaa taatccatct gtttgttcat ctaaatggaa ttggatcaat ttttccaaac
   102241 cagcataatc tactgatccc tcttcattca tcggcgtgat cagcgccacg atcgaacctt
   102301 ttatcatctt cattcctcca atattcttgt ccattcatga actgctgggc cagccatttg
   102361 tatcgcatcc tcaccagaga tcatcaagtc tccttgttcc aagtgaacaa ctacctgatc
   102421 tgctgaaatt ttcccagttt ccttagcaac cacataagag gcacagcaac ctgtaccgca
   102481 agcaagtgtc caacctactc ctctttcata ggtacggacg atcaattctt gttcattgac
   102541 tacttctaca aagttgacat tggttttttc tttgaacaaa ggatgatgac agatcagttc
   102601 acctcttttt ctccagactt cctcacgcgc attttcaaca aaaacaacgg tatgaatcgt
   102661 tcctaaaaat aaactagtga tcgttacttt ttcaccattg atctctattt cctggttttt
   102721 tattggataa gtttgattag ctttgatttt ttccggagaa tcatctggca ctcccatatc
   102781 tacgctgcaa taaaaaggtg agggatccaa caccgtaatt tttcttgtgc ctgctaatgt
   102841 ctctacgttg aattcctgtt cattcatcat gttctgatca tttacgtatc gagcaaaaca
   102901 gcgaatgcca tttccgcaca tcggcgcgcg gctgccatct ttgttgtaat agatcatttc
   102961 caacggatcg atttttacgg cgatcaatcc gtctatatca tatttttctt ttgtgcataa
   103021 agaagcggct aattgactat aatctgtgtc ttctgcgtaa tctaataaga taaaatcatt
   103081 tccgcagcca ttatatttat gaaggatcat aggaaacttc cccccttagt agatcagaaa
   103141 atgcttgtct gcgaacaatc agtcttgatt ggccattatt gacaaaaaca actgctggtc
   103201 gtgtcgctcg attgtagttg ctgctcatcg agtatccata agctcccgtg gaataaacag
   103261 ctaaaagatc acccgattct gctttcggca aataagcttc tttaattacc acatcgcctg
   103321 attcacacat ttttcctgca atcgtcactt tctctgtttt ttcttccgac agttttgctg
   103381 ctaaatcaca atcgtattct gcctgataca gagctggacg gatattatct gtcatcccgc
   103441 catctacaaa gtaatatttt ttatgtggtg tctttttgat gaaaccaatc gtgtatagtg
   103501 ttgtaccagc ttctccaaca atacttctac ccggttcgat cagtaattga cgaatggtca
   103561 gttttcgttt ttccaaagct tcttccgtat attcaatcag tttttttagt gcctcttcga
   103621 ctgggatcgg ctgatcattt tgtgtataac gaatcccaaa ccctccgcca agattcaagg
   103681 aaagaggttg gtcaaaatcg gttaagtaat tcgtcaattt gtcgatttca gctaaccaag
   103741 cagtaacatc aaaaatttgt gacccgatat gagcatgaaa tccttctaac tctagatagc
   103801 tgctttcttt tatcaactga agggcttgtt ggcactcttt actttcatag ctcatgccga
   103861 attttgaatc aatatgcgca gtgacgatat attcatgagt atgtgcttct actccgacat
   103921 tcaaccgaag catgatacag atttttttta aatagcgttg gcttaattct gctaataatt
   103981 caacttccat caaattatcg gcaacaatat gcaacaaatc attttcaagt gcatagatca
   104041 gttcctctgg cgtcttgttg ttaccatgga agtagatagt atctctagga aaatcagctt
   104101 gcaaagcggt atagatttcc ccaccactga caacatctag cccgaatcca tattcacgaa
   104161 ctaaatgcag catctcaatc gtttggaatg ctttagaggc gtaaagcact tttgtatcaa
   104221 aacgtttcga tacaaagcct cgcttgaatg acagcatcgt ttgtctcatc ttttcttcat
   104281 catacacata cagaggtgtc ttatactttt ctgccaatgt gcttgctgtg actccgccaa
   104341 ttatcaattc tgtcattttt tcattcctct tttcactttt tttccgtttt tattggaatt
   104401 tcatttgata aagatttgaa ttttattgga ataatattaa acaaaatttt ctgaattgtc
   104461 tagtatattt cgaaatattt ttttaaaaat aagaataaaa atggttataa aaacaaaata
   104521 cccgaactat tagaagctat ttatacataa aaacataaat tcaacactat ttagtgatga
   104581 aaaaatattt tcgcttcaat atagttcgga atagttcgga tattttcaat tttatgaatc
   104641 atttcaattt cttcataaat aagtgcagtt ttttctttct ctagcttttg ccattcatct
   104701 ttcaaaatat aaataaaatc aaatactttt ttatttttca atttgctgat tccacaaaaa
   104761 acctcttgaa aggcagatcc gatgatctgc ctttcaagag gtcaagctct gttttcaaat
   104821 tcttatcaat ccgttagcga attattttga cgcacgtttt acataagaac cttctgctgt
   104881 attgatttcc aacaattcat ctgtttcgat gaagtcagga acattgacta ctaagccagt
   104941 ttccattgtc gctggcttac ctgaaccagt gactgttgca cctttgatgg aaggttgtgt
   105001 ttccacaaca cgtaatacga cagttgttgg taattgaacg ccgatgactt cgctaccgaa
   105061 aaattggatt tttacttcca tgttttctag gatatatttc atttcttctt ctactgtttc
   105121 tacaggaatt tcatattgct catatgtttc caaatccatg aagaaagctg tatcatccat
   105181 cgtgtacaaa tattgtacag gttttgtgtc gatatgtgct ttttcaaatt tttcttctgg
   105241 tctgaacgtt gtgtcgtatg ttgcacctga acggacatct ttcagtttca tacgcataac
   105301 tgtatttcct ttaccaggtt tatggtggct tgcatccaga actttaatca gtttgccgtc
   105361 ttgtacgaaa gtcataccgg ctcttaaatc acttgctgag atcattattt ttgctccttc
   105421 ttttctttat cataatcaac tttattgtat cagacaaccg gccagaaaac tagagtattc
   105481 tctatctttt aaggtctcat gcctatttgt cagaaaaata aacacgggta aacgatgcta
   105541 tcgaaatatt tttttctttc aagcctttga cttttatttt ttttcatgct atcgttaata
   105601 aaaattttac ttggagggat acacatgaca gtcagcaacc aaaaacaatt gaatcgttgc
   105661 tgttgtatgg tgcataaaag cagcatacta tttgtcatgt ctattaattg cccttcatag
   105721 aatgagtacc aggtaactta tctttttatc tactcaattt ttctctatgt ctttcaagga
   105781 gctgatttaa tagtcagctc ctttttttat tatctttttt taggaggccc acatgattat
   105841 ctcgacaatt acagaagcta ttggttccac accgctttat cgctttgaca atcagcacta
   105901 ttctatgcct aaaggttctg ctatttatgc aaaactagaa tatttaaatc ctggaggaag
   105961 tatcaaagat agattgggca gttatttgat caaagaagga tttgcccaag gaaaaatcaa
   106021 tgaaaaaacg acgatcatcg aaccaactgc cggaaataca ggaattggga tcgctctggc
   106081 cgcactcaca tacaaattaa gaacggtttt tgttgttcca gagaagttta gcttagaaaa
   106141 acaacaattg atgaaagcat tgggagcaaa gatcatccat tctcctagtg agcaaggaat
   106201 catcggtgcc atcagcaaaa gtaaaaaact tgcagaggag atatcaaaca gctatctgcc
   106261 tcttcaattt gaaaataaag ataatcctgc tgcttactat catacgttag ggccagaaat
   106321 ctttcatgaa atcaaagaaa atatccatag ttttgtagca ggaattggga gtggtggaac
   106381 ctttgctgga acttctacct ttttgaaaga aaaatatccc gacattcgaa taatcggtgt
   106441 agaaccagag ggctctgtgt taaatggtgg tgatccagcc cctcacgaaa ttgagggtat
   106501 cggtgtagaa ttcattccgc cgtttctttc tcccctttca atcaatcaga tcgagacaat
   106561 ctctgatgta gaagggttta actatactag gcagttagca cgagaacaag gactattagt
   106621 tggaagttcg agtggtgcgg cttttgcagc agcattaaga gaaattcgtc gtttaccacc
   106681 tggtcatcgt gtcgttacga tttttccaga cgcagcagac cgctatttat caaaaaacat
   106741 ttacttatag gaggaaagaa acatgcacat tcaaacaaaa ttgatccacg gaggcatcag
   106801 tgaagatccc acaacaggag ctgtcagtgt acctatttat caaacatcca cttatcggca
   106861 agatggcgtc ggccagccta aacaatatga atattcaaga tctggtaatc ctactcgttt
   106921 tgcattggaa gaactgattg ctgatttgga aggcggtgtt cgaggattcg ctttttcttc
   106981 tggtctttct gggattcatg ccgttttttc tctttttcaa gctggcgatc atatcttatt
   107041 aggagatgat gtctatggag gaacattccg tctatttgac aaagttctta ctaaaaatgg
   107101 tctcgagtac acgatcatag atacgagtaa tcttgataaa atagaacaat ccatcaaacc
   107161 caatacaaaa gcactttatc ttgaaacacc tagcaatccg cttctaaaga ttactgattt
   107221 agaaaaaagt gccactctgg ctcatcaaca tggattgata gttattgctg acaatacatt
   107281 tgctactcct tattttcaaa gacctttaga tctcggttct gatatcgttg tccatagcgg
   107341 taccaaatat ctaggcggac acagcgatgt agtagctggt ttagtgactt ctaaccaaaa
   107401 gatctagccg atcagatcgg attttaccaa aatgctatcg gagccgtact tggtccccaa
   107461 gatagctggt tacttcagcg cggaatcaag acactaagtg ttcgtatgga ggaacatcaa
   107521 aaaaatgctt ttgtggtagc tgattttcta ttttctcatc cagcagtaga aaaggtctac
   107581 tatccaggat tacccgatca tgaactccat ggagttgcta agcagcagat gagcggcttt
   107641 agcggaatga tttcttttac tttaaaaaat gaagaatctg ctattccatt tgttgaatca
   107701 ctccaactat ttactttagc agaaagttta ggtggcgtag aaagtttagt ggaaattcct
   107761 tctgtcatga ctcatgcgtc tattccaaaa gaaaaacgag aagaggctgg cataaaggac
   107821 ggcttgatcc gtctttctgt aggaattgag tatggtcagg atctcataaa cgatttagct
   107881 caggcatttg acagaatcaa gaactagaag tcccaataaa cgacttagca gaaaaatcta
   107941 aaaaatattt cagattgcta caccttggaa acgataagtg ttagaatcaa gtagaaagac
   108001 gtttttgtaa atttcactaa ataattcttt agtgaaaagc atcaaaacga atgaacaaac
   108061 agataggagt cttacaaatg agaatgaatg tcgaaagttt taatcttgac catacaaaag
   108121 tcaaagcacc ttatgtacgt gtagctgatc gaaaaacggg tgcgcatggc gatgtcatca
   108181 ttaaatacga cgtccgcttt aaacaaccaa ataaagaaca catggacatg ccaagtctac
   108241 attcacttga gcacttgact gccgaactaa tccgcaatca cgcagattac atcgtagact
   108301 ggtctccaat gggatgccaa acaggctttt acttgactgt attgaatcat gaaagctacg
   108361 aagacatttt agatgttctt gaagcaacaa tgaaagatgt tcttgaagct actgaagtac
   108421 ctgcaagcaa tgaaacacaa tgtggctggg ctgccagcca tacactagaa ggtgcacaag
   108481 ctttggctcg tgaattttta gcaaaacgcg atgaatggtc tgaagtagaa gcatagtttc
   108541 taaaagaacg taaagatgag aagcaatata gctatcttat cttcgtattt tattaaatat
   108601 ttattgtctg aaaagagttc taaacgggaa aacaaatagc tagttttcag tttagcgctc
   108661 tttttattat ataaaataga aaggagaaaa ctttatgtct atttataatt ttgaaactac
   108721 tttagaagac ggcactgtct attcattgaa aaaatatgca ggcaaaccga taatcattgt
   108781 taacactgca acaaaatgcg gtctagcacc tcaatttaaa caattagaag aactttacca
   108841 agcttatcag acacaaggtc tggttatctt aggctttcct tccaatcaat ttaaacaaga
   108901 gctagattca gcgactgaag cagcagaagc ttgtaaaacc acttatggcg ttaccttccc
   108961 tatgcatcaa ttgattgacg taaatggaga aaatacagat cctcttttta cttatcttaa
   109021 aaatgaagct cctggtactg tcactaaagc aataaaatgg aattttacta aatttttgat
   109081 tgatagaaat ggcaaagtaa tcgaacgatt tgcaccacaa acttctccat tgaaaatgac
   109141 cgctgcaatt gaatccgttc tttaacttaa taaaaataaa aaaagatgaa ctatttctag
   109201 ttcatctttt tgcctttgcg tggcgacgtc ctactctcac aaggggcaac ccctcactac
   109261 aatcggcgct aagaagctta acttctgtgt tcggcatggt tacaggtgta tccttctcgc
   109321 tatcgccacc acactgtggt gttatctttt attgagtaaa ttttgttcac tcaaaactgg
   109381 atttgaagtc a
//
LOCUS       DBBGSZ010000006       106938 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.006, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000006 DBBGSZ010000000
VERSION     DBBGSZ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 106938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 106938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..106938
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.006"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            212..604
                     /locus_tag="ACIZE5_000591"
     CDS             212..604
                     /locus_tag="ACIZE5_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGC6107758.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="ACIZE5_000592"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="ACIZE5_000592"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HGC6107759.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            2698..2943
                     /locus_tag="ACIZE5_000593"
     CDS             2698..2943
                     /locus_tag="ACIZE5_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107760.1"
                     /translation="MKEKDCFYDKLYKLLLQVGKSSSLLGGILSIIMFVLFFYLLFHL
                     KFFSNDFLICLGLTLAMFISSLLCGLNFFCTHKGLKK"
     gene            3165..4775
                     /locus_tag="ACIZE5_000594"
     CDS             3165..4775
                     /locus_tag="ACIZE5_000594"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HGC6107761.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(4752..4964)
                     /locus_tag="ACIZE5_000595"
     CDS             complement(4752..4964)
                     /locus_tag="ACIZE5_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107762.1"
                     /translation="MKMKIFKKFFAKNKISNSALIEKSLLLSIFFPTNNNKSEKEKSD
                     KKIAYPLLLLLFSFYQVQKLFCFVIC"
     gene            5067..5936
                     /locus_tag="ACIZE5_000596"
     CDS             5067..5936
                     /locus_tag="ACIZE5_000596"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HGC6107763.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="ACIZE5_000597"
     CDS             6101..7372
                     /locus_tag="ACIZE5_000597"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGC6107764.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="ACIZE5_000598"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="ACIZE5_000598"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HGC6107765.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="ACIZE5_000599"
     CDS             8763..9026
                     /locus_tag="ACIZE5_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HGC6107766.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="ACIZE5_000600"
     CDS             9471..9920
                     /locus_tag="ACIZE5_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC6107767.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="ACIZE5_000601"
     CDS             9977..11395
                     /locus_tag="ACIZE5_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HGC6107768.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="ACIZE5_000602"
     CDS             11395..12255
                     /locus_tag="ACIZE5_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HGC6107769.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="ACIZE5_000603"
     CDS             12429..13202
                     /locus_tag="ACIZE5_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGC6107770.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="ACIZE5_000604"
     CDS             13349..13714
                     /locus_tag="ACIZE5_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HGC6107771.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="ACIZE5_000605"
     CDS             complement(13862..15070)
                     /locus_tag="ACIZE5_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6107772.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="ACIZE5_000606"
     CDS             complement(15089..15367)
                     /locus_tag="ACIZE5_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107773.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15560..16216
                     /locus_tag="ACIZE5_000607"
     CDS             15560..16216
                     /locus_tag="ACIZE5_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HGC6107774.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16658..17455)
                     /locus_tag="ACIZE5_000608"
     CDS             complement(16658..17455)
                     /locus_tag="ACIZE5_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HGC6107775.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="ACIZE5_000609"
     CDS             complement(17452..18636)
                     /locus_tag="ACIZE5_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HGC6107776.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="ACIZE5_000610"
     CDS             complement(18661..19908)
                     /locus_tag="ACIZE5_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGC6107777.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="ACIZE5_000611"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="ACIZE5_000611"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HGC6107778.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="ACIZE5_000612"
     CDS             21888..22202
                     /locus_tag="ACIZE5_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HGC6107779.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="ACIZE5_000613"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="ACIZE5_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HGC6107780.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /gene="tmk"
                     /locus_tag="ACIZE5_000614"
     CDS             22887..23531
                     /gene="tmk"
                     /locus_tag="ACIZE5_000614"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HGC6107781.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="ACIZE5_000615"
     CDS             23546..23875
                     /locus_tag="ACIZE5_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HGC6107782.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="ACIZE5_000616"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="ACIZE5_000616"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HGC6107783.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="ACIZE5_000617"
     CDS             24863..25687
                     /locus_tag="ACIZE5_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HGC6107784.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="ACIZE5_000618"
     CDS             25680..26027
                     /locus_tag="ACIZE5_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HGC6107785.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="ACIZE5_000619"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="ACIZE5_000619"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HGC6107786.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="ACIZE5_000620"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="ACIZE5_000620"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HGC6107787.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="ACIZE5_000621"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="ACIZE5_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HGC6107788.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="ACIZE5_000622"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="ACIZE5_000622"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HGC6107789.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31684..32451
                     /locus_tag="ACIZE5_000623"
     CDS             31684..32451
                     /locus_tag="ACIZE5_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6107790.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="ACIZE5_000624"
     CDS             32441..34483
                     /locus_tag="ACIZE5_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6107791.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="ACIZE5_000625"
     CDS             34764..34913
                     /locus_tag="ACIZE5_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HGC6107792.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="ACIZE5_000626"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="ACIZE5_000626"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HGC6107793.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="ACIZE5_000627"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="ACIZE5_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HGC6107794.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="ACIZE5_000628"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="ACIZE5_000628"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HGC6107795.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="ACIZE5_000629"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="ACIZE5_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HGC6107796.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="ACIZE5_000630"
     CDS             39330..40412
                     /locus_tag="ACIZE5_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HGC6107797.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="ACIZE5_000631"
     CDS             40412..41215
                     /locus_tag="ACIZE5_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HGC6107798.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="ACIZE5_000632"
     CDS             41285..42025
                     /locus_tag="ACIZE5_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGC6107799.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="ACIZE5_000633"
     CDS             42036..43040
                     /locus_tag="ACIZE5_000633"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017118 - lipoyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HGC6107800.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44929)
                     /locus_tag="ACIZE5_000634"
     CDS             complement(43085..44929)
                     /locus_tag="ACIZE5_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107801.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            45140..45658
                     /locus_tag="ACIZE5_000635"
     CDS             45140..45658
                     /locus_tag="ACIZE5_000635"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGC6107802.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            45786..46469
                     /locus_tag="ACIZE5_000636"
     CDS             45786..46469
                     /locus_tag="ACIZE5_000636"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HGC6107803.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            46778..46851
                     /locus_tag="ACIZE5_000637"
     tRNA            46778..46851
                     /locus_tag="ACIZE5_000637"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46812..46814,aa:Arg,seq:tct)
     gene            47010..47369
                     /locus_tag="ACIZE5_000638"
     CDS             47010..47369
                     /locus_tag="ACIZE5_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HGC6107804.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            47492..49123
                     /locus_tag="ACIZE5_000639"
     CDS             47492..49123
                     /locus_tag="ACIZE5_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HGC6107805.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQFPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(49185..49826)
                     /locus_tag="ACIZE5_000640"
     CDS             complement(49185..49826)
                     /locus_tag="ACIZE5_000640"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HGC6107806.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    50012..50088
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            50108..50416
                     /gene="rplU"
                     /locus_tag="ACIZE5_000641"
     CDS             50108..50416
                     /gene="rplU"
                     /locus_tag="ACIZE5_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HGC6107807.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            50443..50787
                     /locus_tag="ACIZE5_000642"
     CDS             50443..50787
                     /locus_tag="ACIZE5_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HGC6107808.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            50800..51093
                     /gene="rpmA"
                     /locus_tag="ACIZE5_000643"
     CDS             50800..51093
                     /gene="rpmA"
                     /locus_tag="ACIZE5_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HGC6107809.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            51527..54334
                     /locus_tag="ACIZE5_000644"
     CDS             51527..54334
                     /locus_tag="ACIZE5_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGC6107810.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            54525..55016
                     /locus_tag="ACIZE5_000645"
     CDS             54525..55016
                     /locus_tag="ACIZE5_000645"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HGC6107811.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            55119..56108
                     /locus_tag="ACIZE5_000646"
     CDS             55119..56108
                     /locus_tag="ACIZE5_000646"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HGC6107812.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            56141..56944
                     /locus_tag="ACIZE5_000647"
     CDS             56141..56944
                     /locus_tag="ACIZE5_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HGC6107813.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            56965..57879
                     /locus_tag="ACIZE5_000648"
     CDS             56965..57879
                     /locus_tag="ACIZE5_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGC6107814.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            57962..58336
                     /locus_tag="ACIZE5_000649"
     CDS             57962..58336
                     /locus_tag="ACIZE5_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HGC6107815.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            58475..58720
                     /locus_tag="ACIZE5_000650"
     CDS             58475..58720
                     /locus_tag="ACIZE5_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGC6107816.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            58892..59956
                     /locus_tag="ACIZE5_000651"
     CDS             58892..59956
                     /locus_tag="ACIZE5_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGC6107817.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            60202..60627
                     /locus_tag="ACIZE5_000652"
     CDS             60202..60627
                     /locus_tag="ACIZE5_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGC6107818.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            60620..61069
                     /gene="nusB"
                     /locus_tag="ACIZE5_000653"
     CDS             60620..61069
                     /gene="nusB"
                     /locus_tag="ACIZE5_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HGC6107819.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            61166..62020
                     /locus_tag="ACIZE5_000654"
     CDS             61166..62020
                     /locus_tag="ACIZE5_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HGC6107820.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            62021..63358
                     /gene="xseA"
                     /locus_tag="ACIZE5_000655"
     CDS             62021..63358
                     /gene="xseA"
                     /locus_tag="ACIZE5_000655"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HGC6107821.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            63363..63587
                     /locus_tag="ACIZE5_000656"
     CDS             63363..63587
                     /locus_tag="ACIZE5_000656"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HGC6107822.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            63589..64479
                     /locus_tag="ACIZE5_000657"
     CDS             63589..64479
                     /locus_tag="ACIZE5_000657"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HGC6107823.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            64488..65306
                     /locus_tag="ACIZE5_000658"
     CDS             64488..65306
                     /locus_tag="ACIZE5_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HGC6107824.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            65413..65862
                     /locus_tag="ACIZE5_000659"
     CDS             65413..65862
                     /locus_tag="ACIZE5_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGC6107825.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            65880..67562
                     /gene="recN"
                     /locus_tag="ACIZE5_000660"
     CDS             65880..67562
                     /gene="recN"
                     /locus_tag="ACIZE5_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HGC6107826.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(67617..67733)
                     /locus_tag="ACIZE5_000661"
     CDS             complement(67617..67733)
                     /locus_tag="ACIZE5_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HGC6107827.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(67806..68762)
                     /locus_tag="ACIZE5_000662"
     CDS             complement(67806..68762)
                     /locus_tag="ACIZE5_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGC6107828.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            68933..69301
                     /locus_tag="ACIZE5_000663"
     CDS             68933..69301
                     /locus_tag="ACIZE5_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HGC6107829.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            69471..69902
                     /gene="mraZ"
                     /locus_tag="ACIZE5_000664"
     CDS             69471..69902
                     /gene="mraZ"
                     /locus_tag="ACIZE5_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HGC6107830.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            69923..70882
                     /gene="rsmH"
                     /locus_tag="ACIZE5_000665"
     CDS             69923..70882
                     /gene="rsmH"
                     /locus_tag="ACIZE5_000665"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HGC6107831.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            70887..71288
                     /gene="ftsL"
                     /locus_tag="ACIZE5_000666"
     CDS             70887..71288
                     /gene="ftsL"
                     /locus_tag="ACIZE5_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HGC6107832.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            71289..73481
                     /locus_tag="ACIZE5_000667"
     CDS             71289..73481
                     /locus_tag="ACIZE5_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HGC6107833.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            73507..74469
                     /gene="mraY"
                     /locus_tag="ACIZE5_000668"
     CDS             73507..74469
                     /gene="mraY"
                     /locus_tag="ACIZE5_000668"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HGC6107834.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            74483..75844
                     /gene="murD"
                     /locus_tag="ACIZE5_000669"
     CDS             74483..75844
                     /gene="murD"
                     /locus_tag="ACIZE5_000669"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HGC6107835.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            75870..76958
                     /gene="murG"
                     /locus_tag="ACIZE5_000670"
     CDS             75870..76958
                     /gene="murG"
                     /locus_tag="ACIZE5_000670"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HGC6107836.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            76973..78193
                     /locus_tag="ACIZE5_000671"
     CDS             76973..78193
                     /locus_tag="ACIZE5_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HGC6107837.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            78349..79674
                     /gene="ftsA"
                     /locus_tag="ACIZE5_000672"
     CDS             78349..79674
                     /gene="ftsA"
                     /locus_tag="ACIZE5_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HGC6107838.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            79697..80938
                     /gene="ftsZ"
                     /locus_tag="ACIZE5_000673"
     CDS             79697..80938
                     /gene="ftsZ"
                     /locus_tag="ACIZE5_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HGC6107839.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            80955..81632
                     /locus_tag="ACIZE5_000674"
     CDS             80955..81632
                     /locus_tag="ACIZE5_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HGC6107840.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            81646..82245
                     /locus_tag="ACIZE5_000675"
     CDS             81646..82245
                     /locus_tag="ACIZE5_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HGC6107841.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            82326..82547
                     /locus_tag="ACIZE5_000676"
     CDS             82326..82547
                     /locus_tag="ACIZE5_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HGC6107842.1"
                     /translation="MVYALLSWFPGGYQSGLGRLLAKICEPYISLFDRLPLRIGPLDF
                     TILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            82580..83377
                     /locus_tag="ACIZE5_000677"
     CDS             82580..83377
                     /locus_tag="ACIZE5_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HGC6107843.1"
                     /translation="MGGENFDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFL
                     DPRQSYILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYP
                     SKFASLSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVA
                     VRLEPIKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNW
                     TENTRPDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            83398..84105
                     /locus_tag="ACIZE5_000678"
     CDS             83398..84105
                     /locus_tag="ACIZE5_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HGC6107844.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            84367..87165
                     /gene="ileS"
                     /locus_tag="ACIZE5_000679"
     CDS             84367..87165
                     /gene="ileS"
                     /locus_tag="ACIZE5_000679"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HGC6107845.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMCMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(87214..88740)
                     /gene="zwf"
                     /locus_tag="ACIZE5_000680"
     CDS             complement(87214..88740)
                     /gene="zwf"
                     /locus_tag="ACIZE5_000680"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HGC6107846.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(88755..89402)
                     /locus_tag="ACIZE5_000681"
     CDS             complement(88755..89402)
                     /locus_tag="ACIZE5_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HGC6107847.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(89586..89915)
                     /locus_tag="ACIZE5_000682"
     CDS             complement(89586..89915)
                     /locus_tag="ACIZE5_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HGC6107848.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            90092..90820
                     /gene="sfsA"
                     /locus_tag="ACIZE5_000683"
     CDS             90092..90820
                     /gene="sfsA"
                     /locus_tag="ACIZE5_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HGC6107849.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            90836..91849
                     /locus_tag="ACIZE5_000684"
     CDS             90836..91849
                     /locus_tag="ACIZE5_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC6107850.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            91849..93126
                     /locus_tag="ACIZE5_000685"
     CDS             91849..93126
                     /locus_tag="ACIZE5_000685"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGC6107851.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            93189..95891
                     /locus_tag="ACIZE5_000686"
     CDS             93189..95891
                     /locus_tag="ACIZE5_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGC6107852.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            96043..96360
                     /locus_tag="ACIZE5_000687"
     CDS             96043..96360
                     /locus_tag="ACIZE5_000687"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC6107853.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            96390..96710
                     /locus_tag="ACIZE5_000688"
     CDS             96390..96710
                     /locus_tag="ACIZE5_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGC6107854.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            96818..98278
                     /locus_tag="ACIZE5_000689"
     CDS             96818..98278
                     /locus_tag="ACIZE5_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGC6107855.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            98346..98567
                     /locus_tag="ACIZE5_000690"
     CDS             98346..98567
                     /locus_tag="ACIZE5_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107856.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            98598..98780
                     /locus_tag="ACIZE5_000691"
     CDS             98598..98780
                     /locus_tag="ACIZE5_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HGC6107857.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            98780..99193
                     /locus_tag="ACIZE5_000692"
     CDS             98780..99193
                     /locus_tag="ACIZE5_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HGC6107858.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            99316..100497
                     /locus_tag="ACIZE5_000693"
     CDS             99316..100497
                     /locus_tag="ACIZE5_000693"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6107859.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(100568..100732)
                     /locus_tag="ACIZE5_000694"
     CDS             complement(100568..100732)
                     /locus_tag="ACIZE5_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107860.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            100886..100959
                     /locus_tag="ACIZE5_000695"
     tRNA            100886..100959
                     /locus_tag="ACIZE5_000695"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:100920..100922,aa:Arg,seq:cct)
     gene            complement(101028..102167)
                     /locus_tag="ACIZE5_000696"
     CDS             complement(101028..102167)
                     /locus_tag="ACIZE5_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6107861.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            102339..102473
                     /locus_tag="ACIZE5_000697"
     CDS             102339..102473
                     /locus_tag="ACIZE5_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107862.1"
                     /translation="MIKVIFKRITELPEFRLFVDYWYVWFFIVALLIGLDVILERKLK
                     "
     gene            complement(102466..103101)
                     /locus_tag="ACIZE5_000698"
     CDS             complement(102466..103101)
                     /locus_tag="ACIZE5_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107863.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(103214..103849)
                     /locus_tag="ACIZE5_000699"
     CDS             complement(103214..103849)
                     /locus_tag="ACIZE5_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HGC6107864.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(103883..104344)
                     /locus_tag="ACIZE5_000700"
     CDS             complement(103883..104344)
                     /locus_tag="ACIZE5_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HGC6107865.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(104474..104905)
                     /locus_tag="ACIZE5_000701"
     CDS             complement(104474..104905)
                     /locus_tag="ACIZE5_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGC6107866.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(104923..105243)
                     /locus_tag="ACIZE5_000702"
     CDS             complement(104923..105243)
                     /locus_tag="ACIZE5_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6107867.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            105542..106318
                     /locus_tag="ACIZE5_000703"
     CDS             105542..106318
                     /locus_tag="ACIZE5_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HGC6107868.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            106333..106536
                     /locus_tag="ACIZE5_000704"
     CDS             106333..106536
                     /locus_tag="ACIZE5_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6107869.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            106552..106890
                     /locus_tag="ACIZE5_000705"
     CDS             106552..106890
                     /locus_tag="ACIZE5_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HGC6107870.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
BASE COUNT        34906 a        18259 c        22352 g        31421 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtag ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcgaaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg tgcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac
    44881 gtaaataaaa agattctttt ttattatata tgttattaaa aaaagacata aaggtattcc
    44941 tttctaaaac ttgtaatgtt agggtaaacg ttttttaaac taacgtcaat tatttataat
    45001 aaaaaatgag ataaagatga ggaaatagaa ttagaaacat ataattatta aagggaaaca
    45061 tttttacagc tataatttga aaaaatttat cgttattata tgattaagaa ggattgaata
    45121 aagaaagaag ttgaaaacga tacctgatta caaaaaaata acttttataa gttctataac
    45181 gttgattata tttttaattc ttattcttct cgtcgtcttg gttccccgaa tttttggttt
    45241 gactccttat attattgagg acaaagaaat gagtccatat tatgcacaag gaaatctgat
    45301 atatgtacga ccgaaaaata caaatgagat tttagtcgga gatattatta catattatga
    45361 aaattcagga aaaaaaatct cgacgcgtcg cgtaatagcc gttgaaaaca accacgaaga
    45421 tttttataca aaagctgata caaagactta tattgagcct ggagtagtaa aaaagagaaa
    45481 tattatcggt agtcccatct ttcagattcc atatattgga ctagtccttt caaaaacggc
    45541 atttgcatgg attcaggggt tattctttac gattgctttt tgcctaacag gaatcacagc
    45601 atggaatacc tttgtagagt tgaaaaagaa gcggagacga acacagaaat ttttgtaaga
    45661 atgttaaaaa cataaatgta ttccagagat ccaacgactc ttctgaacat gaaacacgag
    45721 aaaacactca tgcagcttgt agatttagtc agttgttcgt ataatgtgtg aagaggagga
    45781 gtagtatgcg caatgaaatg atgcatcgtc ctgtagtcaa agaagaacta ttggatttta
    45841 tgcgtaccca gcaaaaaaaa ttaccgggtg agctaggcaa actggaagaa gaagctcatg
    45901 tagcagaagt accagttatt ccccatgaaa cagttgtatt tttgaaattt ttacttggac
    45961 agcttcagcc tgaacgaatc ttggagatcg gagcagctat cggtttttca tcaagtgtca
    46021 tggccacgac aatcggagaa aacgctcatg ttacgacaat tgatcgtttc gatgtcatga
    46081 tcgagaaagc taaaaaaaac tatgaacgtc taggactgac agataaagtg actttgcttg
    46141 aaggtcaagc agcagatatc ttgccggagt tgtctggtcc gtatgacttt atttttatgg
    46201 atagtgcaaa atcaaaatat attgaatttt tacctgaatg cttacgtttg ttaagaaaag
    46261 gtggcgtttt gatggtagat gacatcttcc aaggaggaac gatcttgctc ccagatgaag
    46321 agattccccg tggcaaacga gctatccatc gtaaattaaa tgaatttctt cgtgttgtga
    46381 tggatcatcc cgatttgaca tcgacaatct tgccattagg tgatggtgtg atcttaatga
    46441 caaaggaatc agaaacaatc gagttgtgat acatgattat ggcagcctgt agataatcga
    46501 ttgaatcgag ggctcaattc gaacttgatg taaaagtttc tatatttgta agtcaattaa
    46561 aggatacagg aaatctaaat aaacaggagt agcatgaagt caatgtagct cctgttttca
    46621 attgataacc ttagaacagc tgaaggagaa tgtctcgttt taaaagattg atttagtagt
    46681 tgggccaaaa taattcatta tttgctaatt aaataactat ttcgtattga cagaagcaat
    46741 ttaattatct ataattattg atgttccgct gattcttgtc atagtagctc agctggatag
    46801 agcatccgcc ttctaagcgg acggtcgggg gttcgaatcc ctcctgtgac gctaaaaaac
    46861 cgttagaaac tgaggtttct aacggttttt ctttgttttt tgtgccaata ttgtttgttt
    46921 tcaaaggcaa ataaaataaa aaaacatcct tatcgagtac aattataagg agcaaaaaaa
    46981 taaaactcat cagaaaagag gaagaagata tgacgatact atctagaatt ttagtgactc
    47041 tagttgcaat tgaatttttt tatatcatgt atatcgaaac ggtgagaact gattctgaca
    47101 cgacaagtag ggtttttaaa atgagtaaag aagagttaag cagaaaatct gttcaaacat
    47161 tgtttaagaa ccaaggagtg tacaatggac tattaggagt gggactactt tatggagctt
    47221 atctttcttc cgcatctaaa gaaatcacaa gtatgctatt aatatctatt ttttttgttg
    47281 cattatatgg cagtttgact agcgatcgtt ggattttact caaacaaggt gggctagctc
    47341 tgttggcatt gctttctatt ttcttataaa tatagaaaaa ataagaattt atctaacagg
    47401 aaactttgtg aaaaatatta ctttatctca tgaaatatga tattctaatg aatggtattt
    47461 tagaaaattt catgaaaaag gagttagata ggtgttcaaa aattatgttt cctcactaaa
    47521 aaaagaattt tcaggttatg atctttcaag atttcagaaa gatcttttgg ctgggatcac
    47581 agtagctgct gtagcattgc ctttagcctt ggcttttggg gtatcaagcg gagctgatgc
    47641 ggccgcaggt ttgattacgg ctatcattgc cggtatcgtt attggcggtt tatcaggcgg
    47701 tttttatcaa atatcaggtc cgacaggtgc gatggcagct atcttgatgt ctattgcggc
    47761 aacaaaggga atgcaaggtg tattgcttgc tactttttta gcgggtctat ttttacttgc
    47821 agcaggactt ttccgattag gaacactgac ttcttttatc ccagcacccg taattacggg
    47881 gtttacttca ggtattgcta tcattattgc attaggtcag atcgataatt tatttggtgt
    47941 tcactcggaa ggtacaaacg ttattgaaaa actaagtagt tatcaaacga taggatttcc
    48001 gataaacaca gcctctttga tcatgggagg gctagtcatt ttagggatgt ttatctatcc
    48061 aaaaaaatgg gcgaaacgaa tgcctagttc gctgctggct atcattttgg caacagcagt
    48121 tatgctattg ttccatttac cagtagcaac tgtgggtaag attccacaaa cattgatcag
    48181 tagtaatcgt ttgaatatgg gagattttag cttttctgcc ttgcaacaag tggcagttcc
    48241 agctattagc attgctttat taggaatgat tgaaagcttg ctatgtggtg cttcggctgg
    48301 ccgaatggca aataagccct tagatagcaa tcaagaatta atggcgcaag gaattggaaa
    48361 tctgttgctt cctttctttg gcgggattcc tgctactgcg gccatcgccc gtacaagcgt
    48421 ggccatcaaa tctggtgcac aaactagatt agctggtatg atacatgcag ttgtcttact
    48481 gctctccatg cttgtttttg cgccagtgat gtcacagttt ccaatgccag cacttgcagg
    48541 tgttttgatt gtgacggctt ggcgtatgaa tgaatgggaa acgatcaagg agctatttac
    48601 taataaatat tggtcagcag ttctattgtt tatccttacg atgatttgta cagttatctt
    48661 tgatttaagt attgctatcg tgatcggggt gatcggcggc tgtgtatttt ttgttgtcaa
    48721 aagcgctgct atcacgattt cattagaaac gatcgattgg caaagaatgg ggctgccaga
    48781 aacggaaaag ctgaataact ggacagtagt gtatattagt ggtccactgt tttttatgtc
    48841 ttcagaaaaa ctcaaaaata aattggaaga actaaatcat cacgatggtg tcattttctc
    48901 catgcgaggc gtaccaagta ttgatttgac ggcacgtgca gtttttgatg aatttcaaga
    48961 aaaagcagag caaagaggac aaacgattat ctatacttcc ttgcagccag aagtagaaaa
    49021 acaactttct cacttgtggg aacatacatt cacgcatcaa catcaaacag ttgctcatgc
    49081 gttgacagct ttacatgcga aatatactgc aattagccat taaaacaatg aaaaagaaca
    49141 gacaagactg taaactgaag attttatggt cttgtctgtt ctttttaata ttgctgtaaa
    49201 agtgaagcta gtacttgcca gtcttgatgg ataacaggta caagggagcg attgtagaaa
    49261 atagctgctg gatgaaaaag tggaagaatt cgatagtttt tttctgacca ttcgtaggca
    49321 tccttttgtt ctgttaattg taagacaggc cctgtataga gttgaccatg atttttggta
    49381 accgtatatt ctttgccaag taaacgttga agaccaatgt ttccaagtgt cgcaattaat
    49441 tttggctgga ccttcatcag ttcgtaatcc aatattggtg catgcgcaaa tacttcggaa
    49501 cgagtaggtg tccgatttgg ataaacagtt tctgactgtt gtgtccgttt attgatccga
    49561 tgagtcacgc gatacgggcg gctccttaca gcactggtga tatacacctc ttctcgtgtt
    49621 aagccagttg aagaaagtgc ctgcatcaat tcttttccag cttgaccgct aaaaggaaca
    49681 tgcgtatcaa tctctgtttt ccctggggct tctcccacga gcatcagttt aggatgaaga
    49741 ggtccttgcc cagcgataaa tccttctaca ggacggccgt tcattcttaa agaagcttct
    49801 tgtatcagtt cttttgggta ttccatttat gctcctcctt tttcttttat tataagaata
    49861 aaagaaacac aatgcgacta ttttatttgg tagaactgtg aggatagaaa agcagaagta
    49921 ttgcttgaat ttttgtttta ctttttgatt ttaaatttag ttgactaacg gttgctgttc
    49981 tggtaagcta gtactgttgt aattgtggac tccacagcta caaccgctca gaacaagtaa
    50041 taagcacagc atatgctgtc acttcggatg gcgagtctaa gtatatcaga aggaggtgct
    50101 ttatagcatg tacgcaatta ttaaaactgg tggtaaacaa gtaaaagttg aagtgggaca
    50161 agcaatctat gttgaaaaac ttgacgttga agcaggagaa aaagttgttt ttgacgaagt
    50221 tatcttagta ggcggagaat ctacaaaagt aggcgctcca actgttgcag gtgcaactgt
    50281 tgaaggtact gttgaaaaac acggcaaaca aaagaaagtc gttactttca aatacaaacc
    50341 taaaaaacat tcacaccgta aacaaggtca tcgtcaacca tatacaaaag tggttatcga
    50401 cgcgatcaac gcttaatagc gtttgagaaa gaaggcctat atatgatcaa aggaacattt
    50461 aagcgaaatg acgcaggtca gatcgtttca ttcactttga ccgggcatgc tgatgctggt
    50521 ccttatggaa gtgatatcgt ttgtgcgggt gtttctgcgt tagcgatcag cactgtcaac
    50581 gggattgcct cattagccgg ttttgagccg attgttgaaa tgaatgaaga agaaggcggt
    50641 tatctttata ccgaagtcac ttcaggaatg acacaagaac aaaacaatat tgctgagatt
    50701 ctattagaaa atcttttatt aggattacaa tcgatagaag ctgaaaactc agaatatatc
    50761 caaattaaaa caattaatga taaataggag gtgcagacca tgttgttatc tatgaatcta
    50821 caattatttg cccacaaaaa aggtggcggt tctacatcta acggccgtga ctcagaatca
    50881 aaacgtctag gtgctaaacg tgctgatgga caaacagtta caggtggatc aattctttac
    50941 cgtcaacgcg gtacaaaaat ctatccaggt gtaaacgtgg gtatcggtgg agacgacact
    51001 ttatttgcaa aagttgatgg cgtagtacgt ttcgaacgta aaggccgtaa caaaaaacaa
    51061 gtgtctgttt atccagtagc tcaagaagct taattgaatc ttatgattaa agaggttgtg
    51121 acaagacttt tgtcacagcc ttttttgttt ataaaaataa aagttgtagt ggaggctacg
    51181 aagtttactt tgtcttttta cacttaatat ttttttgcca atttggaatc aggatgtttt
    51241 gataactatc gttttcaatt gatggaagct atattgtttg ctatcagtga aataattata
    51301 tggtaaacag tgttcttttt cttgtttcca ttataaaaat cgtatcggga tttttcgttc
    51361 ttttaaattg aacatttcta tctatccgcg tgttatcaac aaaacaaaat caggtaaata
    51421 gttgacgaaa cagaaataaa tacatagtat tatgttttga agcctaagta caatagtcta
    51481 tagaaaagga gcgataccat tggcaaaacg cattgaccga atttatatgt atgtcaaaga
    51541 aaaaaccgct catttaacaa aggcagaata tgatcaagga gtaacaacac aggaaattgc
    51601 tgaagtgtta gggattcagc gaacaaatag cagtaaagat ctgaatcagc tagtgcgcga
    51661 aggaaaactg ataaagacag acggacgacc agtacgttac atatatcaaa cactcgttac
    51721 gcacgtaaag ccagttacaa aacatgtagt cagttacaaa gaaacgccgg tctctgaaga
    51781 aaaaaataca ctccaaatag atactaagga tatctttgca aaaatcattg gagctaacgg
    51841 cagcatgaaa aattcagtgg aacaggcaaa agctgcgatt ttgtatccgc caagaggatt
    51901 aaattgtttg attacaggac ctaccggatc aggaaagact tattttgcac acgcgatgta
    51961 tcattttgca aaagcgcatc atgtaataga tgaggaaacg gaactgattg ttttcaattg
    52021 tgctgattat gccaataacc ctgagctttt gatgagtcat ttatttgggt acgcaaaagg
    52081 tgcttttaca ggcgcagatg aagaaaaaat ggggattatc gatcaagcgg atggcggtat
    52141 gctgtttttg gatgagattc accggttgcc gcctgaaggt caagaaatga tcttttactt
    52201 tatggatcat ggaacttaca gtcgtcttgg ggaaacaacg aaatcccatg aagcaaatgt
    52261 acggatcgta ggtgcgacca cagaagaccc aggttcttct ctattagaaa cttttgttcg
    52321 gcgtatccca atcaatatca aacttccggc ttttgaaaaa cgtcctgcaa atgagaaagt
    52381 cgatttagta aaaatcatga ttgcccacga agcaaaccgc acgcagcgaa agatttcttt
    52441 gacagaagat gtagcaaaag cattgatcgg cagtgtgacc tatggaaata taggacaatt
    52501 gaagtcaaat atccagttag tatgtgcacg aggatttcta aatcatatgc aatcacccga
    52561 aatctcgatc acaatcgatg atttgacaga agggattcgt agcggattga ttcaattagc
    52621 aagcaaccgc agtgcaatgg cagagctttc taaaatattg gagccaaaga taactgtagc
    52681 accaaatgat acgatcatga aaatccaatc ggactcctat gagttacctt ataatctata
    52741 tgatatcatc ggagataaag cagctttact gaagtcggat ggtttggatc aagaagcaat
    52801 caatcatttc atttctacag atatcaacat ccatctgaag tctttctata aagaccatgg
    52861 tttttctttt aatgcagaca gcaaattagc agaatttgta gatccgaaaa tcatagaagt
    52921 gaccaatcag atttatgtaa tggtcaaaag atctttacca tatgagtttc agcaaaactt
    52981 tatttatgct atgagcttgc atatcagttc ttttttgaaa aaaatcaact taggagaaga
    53041 acggcatacg aatgataaca tccgtgagat ggcttttgat tttccagatg aatatgctgt
    53101 tgcgaaagaa gtgcgtagtt atatcgaaac gtattttcaa gtggagattc cagaaagtga
    53161 agactattac ttgaccgttc tactcgtctc gttacgggca aatcaagcaa gcggcagaat
    53221 cggtgtagtc gttgcagctc acggaaacag cacagcaagc agtatggtcc aagttgtcca
    53281 acagttgtta gatgcagaga acgtacgagc agtagacatg cctttggata tggatccgaa
    53341 aacagcattg gaccgaattg aacgcaatgt acaagaagta gatgaaggaa gcggggtcat
    53401 actcttagta gatatggggt cccttgcgtc gtttaattcg caaattcaaa gagacactgg
    53461 aattccagta cgtactgttg atatggtaac aacttctcta gttttggaaa ctgtacgaaa
    53521 ggtctcagta ttagggacag atctagatat gttgcatgaa tcattgaaaa attttcgagg
    53581 ttacgcagaa atatcttctg tagaatctgt tcaggaagca aaacctattc ataagaaaaa
    53641 agctgttttg gctatctgcg catctggcga aggtacagca caaagaatca aagaattgat
    53701 cgaacgagcg gtaaacaagc gtcaagaaac agaattagaa gttctagctt tgtcgattgt
    53761 ggaagtgaaa gaagaactgc cagttatcca aaaagaatat cagatcatag ctactactgg
    53821 gattactgat ttgaatatcc aagccccatt tattccttta gaacgtttta ttgatcaaaa
    53881 tatcgaagtc attttggatc agttgctgat ggaatcagaa ttggaggaaa ctgaattcat
    53941 ctccctagat gaagagtcag ctaaaaatac gtgtgttgag tttatctctg ataacttcat
    54001 ctttattaat ggtagtaagt taatcgatcc aatgtggcaa ttttctacac aaatctctca
    54061 gacgacggga atcggcgatg aagaatatgg attcaaaatc aacctagtga tgcacacagc
    54121 aggaatgatc gaacgtatta ttcggaatga accattgact gtggaagaaa acgaattgac
    54181 aaatacaacg aatgatcctc tttatagcca attggcagcc tcagttgttc tgttggaaga
    54241 tcagataaaa gtaaaagtgc cgatagaaga aatgtattat ctgctacgtc tagtccataa
    54301 tcagttagat aaaaaagaat acactgtgcc atgaatacac aaaaacgata cacttttata
    54361 gtgtatcgtt tttgtgtatt ggttaagaat cctttaaatt caattagtgt atcgtaaaaa
    54421 agttggcacg ctttttgctt atagtagtgt gtgctaggag gtggttgttc acacagaaat
    54481 gataggggtt tctgtgaagt agtgaggaag aaggagtttt gcagatggat attcgattgg
    54541 cacgtataga tgatcgttta atccacgggc aagtcgcaac agtttggtcg aagcaaacag
    54601 gtgttgaacg tatcattgtg atcagcgatg tagtcgctca agataaattg agaaagtttc
    54661 tactaaaaga agctgcaccg ccggggatca cagcaaatgt aataaccgtg cagaaaatga
    54721 ttcaaatcta tcatagtgga ttattatcac gagcaaaagt gatgctttta ttcaccaatc
    54781 cccaagatgt tgaagcggtt gtccgctgcg gtgtacagtt gaagtcgttg aatatcggcg
    54841 gtatgagttt tactgaaggc aaatcaatga ttaccaattt tgtttcagta aatcaacaag
    54901 atattgattc ctttcgttac ttgaacagtc aagaagtgga gttagagatt cgaaaagtac
    54961 ctgctgacag gaaaatcctt ttgatggaac tactagcgaa aatcaaaaag gtgtagcaag
    55021 aatggttgtt ggaaaaggtc aaataattct gttgtaatgg ttagcaatta ttaatatttt
    55081 tgaatttgtt acaacaaaag taaataggag gtataaatat ggtagggatt atcctagcaa
    55141 gtcatggaca atttgctgaa ggaatcttac aatccggttc aatgatcttt ggcgaacaag
    55201 aaaacgtcaa agccgtgatt ttgaaaccaa gtgaaggtcc agatgacttg agagccaaat
    55261 tggaagaagc ggttgcttct tttgataatc aagacgaagt gttattctta gttgatttat
    55321 ggggcggaac accgttcaat caatcaaaca cattattcga agagcacaaa gataaatggg
    55381 caatcgtcag cggtttgaat ttaccaatgt tgattgaagc ctacgcatca cgcttttcaa
    55441 tggaatctgc tcatgaaatt gcagcacaca tcattgaaac agcaaaagac ggtgtaaaag
    55501 taaaaccgga agaattagaa ccggcagaag caccgaaagc agcagttgaa gacgcacaac
    55561 ctaaaggagc acttccagaa ggaactgtgg tcggagacgg aaaaatcaaa tatgtattag
    55621 cacgtgttga ctcacgtctg ttacatggac aagttgcgac agcttggaca aaagcagtgc
    55681 aaccaaaccg tattatcgtt gtttcagatg cagtatcaaa ggatgatctg cgtaagagac
    55741 taatcgaaca agctgctcct ccaggtgtaa aagcaaatgt tattcctatt agcaaaatga
    55801 tcgaagtagc aaaagaccct cgttttggaa ataccaaagc attgctttta tttgaaaatc
    55861 ctgaagacgt attgacagct gttgaaggtg gcgtagacat caaagaatta aatgttgggt
    55921 caatggcgca ttcggtcggt aaagtcgttg taagtaaagt attgtctatg ggacaagaag
    55981 acgttgaagc gtttgagaag cttgaacaaa aaggtgtgaa attcgatgta cgtaaagtac
    56041 ctaatgattc acgcgataac atggatgata ttttgaaaaa agcaaaagct gaattagcaa
    56101 aagcgtaata aataatatta aaatttatag gaggcttatc atgtctatta tttcaataat
    56161 tttagtcgta ttagttgcct ttctagctgg tatggaaggt attcttgatg aatttcaatt
    56221 tcatcaacca ctagtggcat gtacattgat cggtttagtt accggtaacc tcgaagctgg
    56281 tatcgtactt ggcggtacgc ttcagatgat cgctttaggt tgggcaaata tcggtgccgc
    56341 tgtagcacca gatgctgcat tagcatcagt agcatcagca attattttag ttttaggtgg
    56401 acaaggtgtt aaaggtgttc cttctgcgat cgcgattgcc gttcctttgg ctgttgcagg
    56461 gttgttctta acaatgatcg tacgtacaat cgctgttcca atcgttcatt tgatggatgc
    56521 ggctgctgaa gaaggaaaca tccgtaaggt tgaaatgtgg cacatcattg ctgtatgttt
    56581 acaaggggtt cgtatcgcgg tcccagcagc agcgttgcta tttatcccag cacaaactgt
    56641 gcaatcattc cttgaatcaa tgccagcatg gttaacagat ggtatggcta tcggtggggg
    56701 aatggtcgta gctgtaggtt acgctttggt aatcaacatg atggctacaa aagaagtatg
    56761 gccattcttc gttattggtt tcgttgtagc tgcaatttct caattaacat tgattgctct
    56821 aggtgcttta ggtgttgcat tagctcttat ttacttgaac ctttctaaaa tgggtggttc
    56881 atcaaataat ggaggcggaa gcaactctgg tgacccttta ggcgacattt tgaatgacta
    56941 ttaatcttga aggaggaaaa taaaatggca gaagaaaaaa tcaaattatc aaaaaaagat
    57001 cgtttagctg ttgcgtggcg ctctaccttc attcaaggtt catggaacta cgaacgtatg
    57061 caaaacggtg gctgggcatt ttctatgatt ccagcaatca aaaaattata caaaacaaaa
    57121 gaagaacgtt ctgcagcatt aaaacgtcac ttggaattct ttaatacaca cccatacatt
    57181 gcttctccaa ttttaggggt tacattggct ctggaagaag aacgtgcgaa tggcgcgcct
    57241 gttgatgatg tagcgattca aggggttaaa gtaggtatga tgggtccttt agctggtgtt
    57301 ggtgacccag tgttctggtt tacagtacgt ccaatgctag gtgcactagg tgcttcatta
    57361 gctatgggag gaaatatcct tggaccaatc atcttcttct taggttggaa cattattcgt
    57421 tgggcattca tgtggtatac acaagaattt ggctacaaag ctggttctaa aattactgat
    57481 gacctttctg gcggattgtt acaagacgta acaaaaggtg cttcaatttt agggatgttc
    57541 gtattagctg cccttgtaca aagatgggta tcaatcaaat tcttaccagt tgtatcaact
    57601 gtaaaattag ataaaggtgc ttacatcgaa tgggataaat tgccttcagg tggtgaagga
    57661 atcaagagtg catttgaaca agttaataat ggcttagccc tttctcctga aaaggtaaca
    57721 acattacaag acaacttaga ccaattgatt cctggtttag ctgcattagg attaacattg
    57781 ttatgtatgt ggttgcttaa gaaaaaggtt tctccaatcg ttatcatcct tggtttattc
    57841 gtagtcggtg ttgttggaca cgtcatcgga cttttataat ccataaaaat atagctcggg
    57901 cgttgtcccg agcttttttt atatagtata ctgttcataa acaaatatct ggagggagaa
    57961 aatggttcaa tcaatcaata caaaagtaga cttggtaatt gatgctactt cgtttacggg
    58021 tctgacagat tacgggcaaa tcatgatagg taataatggt tttgagtttt accatgcgcg
    58081 agatagacgc aaatatatcc aaattccatg ggaagaagtg gattatgtac tagcatcagt
    58141 catgctaaag ggaaaatgga ttcctcgata tgccattcaa acgaaaaaaa atggtacata
    58201 cacattttct tccaaagaac ctaaaaaagt gcttcgtgcg atcagagaat atgtagatga
    58261 agatagaatg gtacaatcat tgagtttctt tgatgtagtg aaacgtggta ttcgtagtat
    58321 gtttaaacgc aagtaaaaaa taaagaaaac ttctaagagg aggttttctt tattttttta
    58381 ctttgcagaa gaaaatatga aatagcaaaa ccaattattt gtccccttta aatcccatat
    58441 gctaaaattg attagcaaag aaggaggtta tattatgagt tggttatgga cattgattgt
    58501 tggagccgtg atcggagcaa ttgcaggtgc gatcaccagt aaaggaaatt cgatgggctg
    58561 tgtaacgaat atcattgctg gactagtcgg ttcaagtatt ggacaagcga ttttcggcga
    58621 atggggacca aaagctgcag gtatggcact tattccatct attttaggcg cagtgatttt
    58681 ggtagcagtt gtctcatttt tctttggaaa acgatcataa gtttttacaa aatagtaaac
    58741 taaaaggagt tgcagcgaga ctgtgactcc tttttggctt tatttattta aaataaaaag
    58801 aagttttccg gaaattttta tttaactgtc gtgtacgaag aaaagtttgc tataatggaa
    58861 aaaagcgtgc aaagaaagag ggagtttcat tatgatgcta cgtgtagaaa aattgcgcaa
    58921 aaaaatgcaa gaagaaaatt tggattcatt tttggttacc agtccgtaca atcttcgtta
    58981 cttaacgaac tttacaggta cgacaggatt agctgttatt actttggaaa aagcattttt
    59041 tattactgat tttcgttata ccgagcaggc ggcagcgcag gctcaagggt ttgaaattat
    59101 taaaaatgtc ggacctattt ttgatgaggt agcaaactta gtacgcaaag aagaactgca
    59161 ctcattagct tttgaggaaa caacagtctc atttttagaa tattcggttt tagaagaaat
    59221 catcgatgcg gaattagtac ctgtttcaca gatgatcgaa gaactcagag aagtgaaaga
    59281 tgaagaagaa atcgctatta tcgaaaaagc atgtcatatt gcggatatgg catatgatca
    59341 catcctgaaa atgatccaac cgggcatgac tgagattgaa gtcgcaaatc aactagactt
    59401 ttatatgcgt tctcttggcg cttcaggtgt ttcttttgat acgatcgttg ctagcggatt
    59461 gcgttcggct atgccgcatg gtgtagcaag caaaaaaatc atcgaacaag gtgacttgat
    59521 cacattggac tttggttgct attacgaagg gtacgtttcc gatatgacac gtacattcgc
    59581 tattggtgat cctggggaaa aattaaaaga aatttatcaa atagtcttag atgctcaatt
    59641 agcagttatt gatgctgcaa aaccaggaat gactggtgtc caattagatg cagttgctag
    59701 agattatatt tcaaaacatg gttacgggga agcatttgga cattctacag gacatgggat
    59761 cggtttagag atccacgaag gaccaaacgt ttcttctcgt gcagaaaagc aatttgtacc
    59821 aggaaatgtg atcactgatg aaccagggat ctacttacca ggaatcggtg gagtacgtat
    59881 tgaggatgac ttgttgatca cagaagatgg aaatcgtgtg ttgactcgtt caccaaaaga
    59941 attgatcatc ttatagtttc atcaatagaa gaagtaagcg taaaaatcag tgttcacaga
    60001 ctttgttata gaaaatcact cgatttaatg atacactata gaagaacttt taagctgtaa
    60061 gagataataa agttgggtgt tttctccaat tcatagcagt ttgcagctga tcggcggcag
    60121 ttttcttacc acgtgatcac tatgccgcat catagagaat tcggatgtat ctcgtgctta
    60181 ggcaaaggga ggaataaata aatggcagat gaaaaaaatt tgattttaaa cgcaaaccaa
    60241 gatttaggag agatcgtgat cgctcctgaa gtcatcgaag taattatcgg gattgcagct
    60301 tctaaagtag aaggcgtata cggaatgcgc ggaacttttg ccagcaatgt cactgaatta
    60361 ttaggacgtg cagctcacgg aaaaggtgtt tacttagcaa acgaggaaga tggcttgaaa
    60421 gtagatcttt actgttatct agaatatggt gtttcagttc ctaaagtagc aatggaaatg
    60481 caggaacggg tcagccagca agtccttttc atgacggata tcgatttatc tgaagtcaat
    60541 atccatgtag tagctgttgt tcctgaaaaa ttagaacaac caacaatcga agaacttttt
    60601 gaagacgaag aggaagagaa tgaataaaga attatcaaga cacgagattc gggaaatggc
    60661 attgcaggct ttatttccat tagacttcaa tgcagaccta acaaaagaag atgcgatttt
    60721 caacgcaatc gaattagacc accgcgacat gatcaacgaa gatgaatcag agtttgttcc
    60781 tgtttatctt gatacgctag ttggcggtgt ctgtgcaaaa aaagatgaat tggataaagt
    60841 gattgaaaaa catttaaaaa acaattggca catcaatcgg atctcaaaaa tggatttggt
    60901 gatcttgcgt atcgcgattt ttgaaatgac ttatgtgaca gatgtaccag cggctgttgc
    60961 tttaaatgaa gcaatcgagt tggcaaaaac atttagtgat gaccgttcac gtaaattcgt
    61021 caacggtgtt ttatccaatg tattgaaaga attagaagct ggggcgtaag tcctagcttt
    61081 tttctatgaa tcatcataaa cctgttataa atcgggaaaa ttctatggta gaatgaaaac
    61141 acaaaaaata tctgggagtg gttagatggc agaattgatt aacggaaaag aattagctga
    61201 aaaaatgcag gcagagattg ctgaaaaaat ccaaaaattg aaagataatg gtatccatcc
    61261 cggattagtc gttttattgg taggggaaaa tccagccagc caaatctatg taagaaataa
    61321 agaacgtgta gcaaaagaaa tcggaatcca ttcattggta gagcgttatc ctgagacgat
    61381 ttctgaagac gaactacttg cagaaattga aaaatacaat caagatccta gttttcatgg
    61441 tatattggtc caattaccat tgccaaagca tatagatgaa gaaaagatcc tgttagctat
    61501 ccgccctgaa aaagacgtag acggttttca tccgatgaat ttaggcagac tccttgcggg
    61561 taaaccggac aagattcctt gtactccata cggcatcatg aaaatgtttg aagcttattc
    61621 tatcgatccg gcgggtaaac gagcagtagt tatcggacga agcaatatcg tcggtaaacc
    61681 gatggctcag ctactcttga tggcagatgc aactgttact gttgctcatt ctaaaaccga
    61741 aaatctggct gaactggcac aagaagcaga tattttagtc gtagcaatag gacgtggaca
    61801 ttttgtcaca aaagaattcg taaaaccagg tgctgtagtg atagatgtag ggatgaatcg
    61861 tgatgctaac ggtaagctga tcggtgatgt gaaatttgat gaagtggagc ctattgcagg
    61921 ctggatcact cctgtgccaa agggtgtagg gccaatgact atcacgatgc tgatgtatca
    61981 aaccgtaaaa tctgccgaag cttttggagc aggtgaatag atggcacaag aatatttaac
    62041 tgtcactaca ttaacgaagt atttgaaaag aaaatttgat gccgatcctt atttagaacg
    62101 cgtatattta acaggcgaaa tatcgaattt ccgtttacgt gccaatgccc atcaatattt
    62161 cagcttaaaa gatgaccatg caaaaatatc tgctattatg ttcaaaggag cattccaaaa
    62221 attacgattc cagccaaaag aaggaatgaa agtccttgtc gttgggcgta tttcattata
    62281 tgaagcggga ggttcttatc aaatctatgt agagcacatg gagcctgatg gaataggtgc
    62341 tttatatcaa gaattggaag aacgaaaaga aaagctgatg aaggaaggcc tttttcaagg
    62401 gcctaaaaaa atgctgccac gtttcccaaa gcgaatcgcg gtccttacca gtccaagcgg
    62461 agcggttatc cgcgatatca tcacgacggt gaaaagaaga tatccaattg tccaattggt
    62521 tttgttccca acagttgtac aaggaaacca agcagcggac aatgttgtca ggaatatcca
    62581 gagagtagaa gagatgggca atttcgatac aatgatcatc ggtcgtgggg gtggttcgat
    62641 tgaggattta tggccgttta atgaagagcg ggttgctcgg gcgatttatc aagctaatac
    62701 gccggtgatt tcatctgtag gacatgaaac agataccacg atcgctgatt tagtagcaga
    62761 tgttcgggct gccactccaa cagcagctgc agaattagct gttcctgttt tgtcagaaga
    62821 gttgatgcgc attcaagaac ggcaagctag attgcagcag gcgtttgtac gccagatcca
    62881 gcgcaaacaa gaacggttcg agcgtgctcg acgttcctat gtatttcggc agcctgaaag
    62941 attgtatgaa ggtcagacca tcaaattaga ccagttgaaa cagcgattat atcaagctac
    63001 acagcaaatt tatcatgcga aagaaaaaca aacgatcgca ttaagccacc aattggaaca
    63061 agtggctccg ctttatcgag ttaaagcagc tcgccaagaa actgcttatc tagaaaaacg
    63121 cttagaagag aaaatccaac aatatatgaa acaacagcag cagcgttttg ctcaagctgt
    63181 tcaatctctt gatttgttga gtccattgaa aatcatggga agaggctaca gctatacgac
    63241 gttaaatgat caagtagtaa aaagtgtcac cgagattcat caaggggatt tgctgacgat
    63301 ccattatcaa gatggaatcg ttaaaggaca agtacaagag atagacaaag gagaataaaa
    63361 atatggaaaa tccaactttt gaagagtcac tgcaagaatt agaaaaaatt gtcatgcagt
    63421 tagaacaagg agacgttcca ttagaatcag ctctagattc gtttaaacga ggaatggaat
    63481 taagcaaaca ttgccaagat acattagcta aagcagaaga gaccttgacg aaaatgatga
    63541 cagaatcaaa tgaagaagtt gattttgacg gaaacgagga aagctgagat gagattaact
    63601 gacttttcag ctattcatct acctgctgta gaaaaagaaa tcttgtcttt tttagatgag
    63661 catacaacgg atagaggact ctatgatgcg atgagttatt cagtgaaagc aggcgggaaa
    63721 agaatacgtc ccttattact tttaacggcc gttgcttcct ttgatgagcc tattgatgtt
    63781 cccgtctatc aagtagcagc tgctttagaa atggtgcata cgtattcctt gatccacgat
    63841 gatttgcctg cgatggacaa tgatgatctt cgtagaggaa aacctaccaa tcataaagta
    63901 ttcggcgaag cattagctat attggccgga gatggtttgc ttacaggagc attccagcta
    63961 atcagtatgg cacacttagg taattctcct aagcttctgc tgcttcagca attagctgtt
    64021 tgtgcgggat cacaaggtat ggttgctggg caagctgcag atatcgaggg cgaatcgaaa
    64081 aagctttctt tagaagaatt agcatttatt catgaaagaa agacagggca tttgattcgt
    64141 tatgccttgc tggctggtgg catattagcg aagcaacctg aagaaatctt attgctactt
    64201 caacgattag ccgaacattt aggtttagct tttcagataa gagatgatct actcgatgtg
    64261 attggtacaa cgaaaacatt agggaaaaca gctggtaaag atgaacgtat ggaaaaaaat
    64321 acttacccgc gtttattagg cctagaaaag acacgtgagg cgttggagat tgagctgtta
    64381 tccgccaaca agatcataga caaattagaa gaggacgttt tttcttttga tggcgggctg
    64441 atgcgccaga tgatcaagca atttgatgtg gagaaatgag ggaaagaatg gaaaaagaac
    64501 gcgtagatgt attagcggtc aaacaaggat tatttgaaac aagagaacaa gccaaacgtt
    64561 cagtgatggc tggtttgatt tacaacgaaa aaaacgagcg gtttgataaa ccgggagaaa
    64621 aaattccagt gagtagtgaa ttaagagtca aaggtaaaaa acttccttat gtttctcgag
    64681 ggggattaaa attagaaaaa gcactcaaag catttgatct atctgttgaa ggaaaaacat
    64741 tgttagatat tggtgcatcc actggcggat ttactgatgc agctttgcaa aatggcgcaa
    64801 aaatgagtta tgctttagac gttggctaca atcagctagc ttggaaaata agacaagatc
    64861 ctagagtcgt cgtaatggaa agagtgaatt ttcgttatgc aaaacccgaa gactttacct
    64921 taggaattcc agaagttgct gttatcgatg tttcttttat ttcactaaaa ctgatgctgc
    64981 ctccattaca tgctatttta aaagaagagg gagaagtgat tgctttaatc aaaccccaat
    65041 tcgaagcagg cagagaagct gtagggaaaa acggaattgt tcgtgaccct cagacccatc
    65101 aaaaagtttt agaagacatt ttgtcatttg cggcacaagg tggatatgat gtgctggaat
    65161 taagttattc tccgatcacg gggggagaag gaaatatcga gttcttggct cacttgagga
    65221 aagtacccga aagcggaaca atcaattcag ctattaatat ggcagaagtg gtttcaaatg
    65281 cacacgaaca gtttgaccat aaataaattg taactgtgaa aatcaagtga gaagtatgcg
    65341 gattcttctt tattatacca aggaaataag ctatcattga ttaagaagaa tatgctaagg
    65401 agcgaagacg taatgagaaa aaaagatcgg catcgtttga ttactcgatt gttgagtgag
    65461 caagatatcc gaaagcagga agaatttgtt gaaatcctga aaagcaaagg aatatctgtt
    65521 actcaagcta cgatttccag agatataaag gaactgaaac tgatcaaggt accggcttca
    65581 gatggcggct accgttatag cataccagct gaaacaaacg aagatgtaaa tactaaattg
    65641 gaaaaactat taaaagacgc tttcgtggca gttgaccaaa tggaaaaatt tgttattttg
    65701 aaaacattgc cgggaaatgc ttcggcagca gcaaatttga ttgataaacg ttacaagaaa
    65761 gaattatttt cgattatcaa tgatgacgat aatgttttga tgattacacg aactgaagac
    65821 caggcagttt tattgaagaa agacttcctg cattaccttt aagttgagga gcgaatgtga
    65881 tgctacaaga aatcagtatt actaactttg cgattattcc ggaattgcgg ctttcttttc
    65941 acgaaggaat gaccgcgctg accggagaga ctggtgcggg taaatccatt attatcgatg
    66001 ctttaggtct gttagcagga ggaagaggtt caagcgatta tatacgtcaa ggagcagaaa
    66061 aatgtgtgct tgaagggttg tttgaactac caaaacaaga aggattctct gaactgatgg
    66121 ttgaattagg gatcgaaaca gatgaggaca atctgattgt tcgacgggat atgtccttaa
    66181 ctggaaaaaa tgtttgtcga gtgaatggtc atattatcac attagctaat ctgagaagaa
    66241 tcggcagtta tttagtagat atccaaggac aaaacgaaca tcaggaactg ctccagcctg
    66301 aatcacatct tgctttattg gatcgttttg gagatgtagc tttccaacag aagaaaaaga
    66361 gttatcagca agaatatatc tcttatcgtg agctggaaaa aagggtacga aaagtgcagc
    66421 aaaatgaaaa atcctatgtt cagagaatag atatgctcca tttccagcaa gaagaaatag
    66481 ctgctgctga tttgcaagtc ggagaagaag agaaattaaa agaagaaaga gaaaaactta
    66541 gcaattatca aaaaattgct gatggattag ctgcaggtta cggagcactg acgaataatg
    66601 aacaaaacag tgtagatggt gttggcttgg ccgtttcaga actgcaaggg atcgcccatc
    66661 tagatgtgga gtatgaagca atttatgaaa atatccaaag tgcttactat ttgctgcaag
    66721 atgcaatcgg cgatatgagt cgtcagattg atttattgga gttagatgag agtcgtttag
    66781 aagaagttac gcaacgttta gaattaatcc gacagttgaa acgtaaatac ggcgaatcca
    66841 ttgagtcaat attggcttac tatgacgaaa tcaccgaaga gctagcttct tctgattttt
    66901 cagaaggtca attggacaaa atgaaagagg aactagagca aaaagagctt ctacttcagc
    66961 aacaagccgc agatcttcat gaagcgcgta aaaaaatcgc aaaagaattg gaaaaatcca
    67021 ttctgcatga attgaaaagt ctgtatatgg aaaacactga gtttgaggta cgtttcttaa
    67081 aagaagaaaa tagacaattg aatcatgatg gatttgacca aatcgaattt tacattacga
    67141 ccaatccagg agagccactg aagcctttgg tgaaagtcgc ttctggtggc gaactgtctc
    67201 ggatgttgct tgctttgaaa actatttttt cttctgagca aggtgtgaca agtattattt
    67261 ttgatgaagt ggatacaggt gtgagcggaa gagttgcaca ggccatcgca gataaaattt
    67321 ctcaaatatc gaaatactct caagttttgt gcatcactca tctgcctcaa gttgctgcag
    67381 tcgccgacta tcaatattat attgtgaaag cagtgattga tggacgtacg caaacttctg
    67441 tttcagagtt gaaaacaaaa gaaagagaag aagaaattgc acgtatgctg gctggaagtg
    67501 agattacaaa actcacactc gaacatgcaa aagaactatt gaaactcgca aaaaggacct
    67561 gagccacctc gcagtggttc aggtcctttt cagcagctga tagctatatt ttatttttac
    67621 atgacactca ttacagcagt caatacaaca gatccaatcg ttaaaatcag cattgtccaa
    67681 atgacaaatt ttgttacttt agcaaaagta cttgtttgtt ttttttcacg cattgttttc
    67741 aacctcgtca ttaattagtt gattcaagtg tacaatcttt tttccatttc cacaagaggg
    67801 cttttttata aaaacttccc tttttttaaa taataggtag ttacgataca aataaataat
    67861 gttaatagaa ctagccatat aaaggcatca tccctttcag caataggtaa cttaatgttc
    67921 attccataga tactgccgac gattgtcggt atagttaaaa taatcgttaa agaagttaaa
    67981 attttcataa tattattcag attattcgat acgattgctg aaaaagtctg attcatttgt
    68041 tctactagtt ttaattgaat gcgagaagta gtcattgcct gctctgtttc caccaataca
    68101 tcacgtaaat gatttttcaa agcatgattt tcttggaaaa gtttattttg cgctagttct
    68161 ttcaatgcat ctaaattagc agaagtcgct tctctgaaat aaacgaggct tttttggata
    68221 tccatgattt gataaagttg tttgttttca gtggatactt gaagtttggc ttccaaagta
    68281 tcgcattgag attgaagcgt agctaaataa ctgttgtaag agagtgtgac ctgccaaatg
    68341 aattgaaaga agatattgag attaggcgaa atatcacttt ttggaaaggt ctggctaaag
    68401 actttcttta aaaacagtgg ttcatgattc gtaattgtga taagcttctt tttgggcgtc
    68461 aaaataatag agagcgggta tgtatccact tgaaaataac cgctaggact tgttttagca
    68521 aaaggatatt gtaacaataa taacgctggc tttgtcaact ttgattgatt gaattcttct
    68581 gtacgggaat tttctgcatc gtccaatatg gaagtgatgt aatctgacgg aatttcaaat
    68641 tgatgtgtca gctgatgaat ctcttcttga ttaggacgtt ctacacaata ccagatcgtt
    68701 tggtcagttt cctttccggt attacgcagt ttctcattat ctaatgtaaa atatttgatc
    68761 atgattttcc tcctgttgcc tgtttctttt attataacgg atagggaatt ggaatacatg
    68821 gaatgtgttt gtaagatata gaatataact gcataaattt aaataaaatg aaacagttgt
    68881 gtaaagtata tacagtatac ttgaagcaac gataaaaaag gagtttacgt tcatgggcac
    68941 attcacacca cttatcttgt tttggtatat ttacccggta atcgttttgt ttggttgcca
    69001 atttcttgta aaattatttt cgttaaatcg tcgttttaaa ataaaagccc ctgatttggc
    69061 gattcctttt ttgtggggcg gtatgcatgc attgtctaga aatacaggga caatttctat
    69121 cttaccgttt ttctttattt ctgttttgct aatgggaatt tgtattgctg ttttccaagc
    69181 atattattat gaagaaatta tttatccgcg ttatttcaag atgacttggc gtttggtttt
    69241 tctgttgaca atcgtcttgt acgctgtctt gatcattgtg aacatacttt cttacctatg
    69301 aaaaaaatag aaaagctgta aaaagtcttt taaaaggctt tttgcagctt gatttttaaa
    69361 aaaatgttta tgaataaaaa aagttgttcc cggatttccc agaaaaggtg gtagaaagtg
    69421 ggggattgtg gtagactaat tttagttagt ggaggaatgg ggggctttca atgttgatgg
    69481 gtgaattcca acataatatt gatgcaaaag gacgtttaat cgtgccctca aaacttcgtg
    69541 aagaacttgg cgaaaagttt gttctgacac gcggattgga tggctgtctt ttcggctatc
    69601 cgatgagcga atgggaaaat ctggaagcta aactgaacga aatgccgttg gctaaaaaag
    69661 acgcacgtac ttttgtgcga ttcttctatt cggctgccac tgaatgcgaa cttgataaac
    69721 aaggacgaat caatataccc agcacgttaa gaaattatgc agctttgaca aaaggttgcg
    69781 tagtcatcgg tgtatctaac cgaattgaaa tttgggatga gacacgatgg caagattttt
    69841 ctgcagcagc agaagagaac tttgacgaaa ttgctgaaag tatgattgat ttcggactat
    69901 aagaatagga agaggctgac taatgactga aacatttcaa cactatacag tcatgttgaa
    69961 agaaacggta gatggattga acatcaaacc ggatggcgtt tatgtagact gtacactcgg
    70021 cggtgccgga catagtgaat atttattaag ccaactaagt tctaaagggc atctgtatgc
    70081 gtttgaccaa gatcaaaaag caatcgatca cgccaagctg cgtttagctt cttatgtcga
    70141 acaaggtatg gtcacattta tcaaagcgaa cttcagagaa ttagaagaac gcttgagtga
    70201 gcatgtagat aaggtagacg gcattttgta tgatctaggg gtttcctctc ctcagctaga
    70261 tgaagcagaa cgtggattta gttatcatca agatgcaccg ttggatatgc gcatggatca
    70321 gtcagctcct ttatccgctt atcacgtaat taatgaatat tcctaccatg aattagtaaa
    70381 gattttcttc cgctatggcg aggagaaatt ttccaaacaa attgctcgtg aaatcgaacg
    70441 agtacgaaaa acaaaaccaa tccaaacaac tggtgagctt gtcgaaatca ttaaacaagt
    70501 catcccagct cccgcaagaa gaaaaggcgg gcatcctgca aaaagaattt ttcaagctgt
    70561 gcggattgca gtaaatgacg aactcggtgc cgaagaggcc tctttagaac aggcaatccg
    70621 gttattgaaa gtcaatggaa gaatcagcgt aatcacattc cattcattgg aagacagaat
    70681 tgtcaaaagt atgtttaaag aatatagtac ggtacaagat ctaccaccgg gacttcctgt
    70741 catacctgac gaattccaac cagaactgaa agtcattact cgtaaaccaa tccttccttc
    70801 agaggaagag ctaacagaaa acaatcgatc acgcagtgca aagttacgta ttgcagaaaa
    70861 aataagaatg aaagaggagt agaatgatgg cagaattaaa gaaaatgcaa gattacgaat
    70921 atgatttacc tgaattggtg gatcagccgg aacaacaaat gcctgattct tcttcgaatc
    70981 aagaaatcat tcttccacaa tcaccggcaa aacgattaaa gcagatttct gctttggaaa
    71041 aaattgctgt ggcaagcgtg gcgattgcta ttgttgcttt atgtgtttta acagttatgc
    71101 tgcgcacaaa tatcagcgga gctgaaaaag aaatcacgtc aatacaaaca gaaatcaatg
    71161 ataaaaagca agaaaaaacg agtttagaac aagaaaaaaa cgaactttct cgtactgaac
    71221 ggattaaaca aatcgcagaa gaaaaaggat tgtctattaa tgacgacaat ttaaggaaag
    71281 tgaagtaaat gagtcttaaa aataaaattc ggcggtttat ggaaaagaaa aatctaaatc
    71341 cgatgaacaa tcgcaaaaaa gtaggtatca ttttatttgc tacgagtatt ggattgttct
    71401 ttttatttgc cgtccgtttc tcgtatatcg ttattggagg tcatgttgct ggtacctcat
    71461 tagctgaaaa aacaaaacag ttgtaccaag gaagtgaagt agtaaaagca aaaagaggaa
    71521 cgatttatga tcgtaacggt gtggcgctcg cagaagatgc ctcctcttat tcaattaaag
    71581 cgatactctc aaaaacatat acctctgggg ataaaaaact gtatgttgaa gaaaagaatt
    71641 ttgataaaat agcagaaatc ctgcataaga atctttctat agacaaaaaa gatgcactga
    71701 atattttaga ggacggcgca aaaaaagagc tgtatcaagt tgaatttggt agctatggga
    71761 aaaatatctc ccaagaaacc aagcaaaaca tcgaagcgga catgaaaaaa gaaggtgtcg
    71821 ctggtcttta ttttgtcgac catcaggctc ggatgtatcc aaatggcgtc ttttcttctc
    71881 attttattgg atacgcagtt ccagacaaag atgagaatgg cttagttggt aaactaggtt
    71941 tggagtctgc ttacaatgat atcttgagcg gtaaagatgg taagattatt tatcaaaaag
    72001 ataattttca aaatcctctg ccaggtacag tggcagaaga agaaaaagct gtcgacggac
    72061 aagatatcta cacgacttta gacagcagac tacaaagtta tttagaaaca ctgatggatc
    72121 aagtaaatga agaatatcag ccagaagaat tgacagcagt cctgatgaaa gcaaaaaccg
    72181 gagaaatctt ggcaatggga caacgaccta ctttcaatcc tgaaacaatg gaaggattga
    72241 ctggaaaaga tgctatctgg cgtaatttct tggtacaaga tagttatgaa ccaggatcaa
    72301 ccatgaaagt tttcactact gcagctgcta tcgaagaagg agaattcaac gagaatgaaa
    72361 ccttccaatc tggaaaaatc caagtagaag atgctacgat caatgaccat gactttggtg
    72421 aaaaaggtgt gctgaccatg cgtcaagctc tttcatggtc aagtaacgtc gggatggtca
    72481 tactggaaca gcgattaggc ggacgatggt ataactattt acaaaaactg ggatttggac
    72541 aaagtactca ttctggatta gatgatgaag taaacggtgc tttacctaca ttaaatattg
    72601 tcgaccgagc aatgagtgct tatggacaag cggtaggtgt gacgaatttc caaatgatga
    72661 aagctttcac ttctattgcg aataacggta caatgattca acctcgatat atcagcaaag
    72721 tggtggatcc ccaaactgga gaagagcgaa caactcaaac agaagttcta gggcaacctt
    72781 tttcaaaaga aacaacagaa aaagtccgtg aatatatgag agatgttgtc gaaagcgaaa
    72841 actacggtag tgcttatggt gtatatagtg tacctggata caatgtatcg gcaaaaaacg
    72901 gaacagccca aatcgcttct gatacagggg gatatcaaac aggagataca gcctacctgt
    72961 attcgattgt ggagatggtt ccttctgaag atccagacta tgtcttgtat ctaacaatga
    73021 aacaccctaa gacatatgat cgaatggcat tggctaaaat cgcaaatcca ttgatgaaac
    73081 gggcaatgga ttttaaagaa actgaagaag attcagatac agaaacaaaa acagaaaaag
    73141 tatccgtagc cgattatcgt aatcttgaag cggacgttgc agcagctgat gctcaaaaaa
    73201 gtggactgca acctgtagtg atcggtaatg gtaaaaaagt acaaaaacaa tctactgcca
    73261 acggtgatca gttgatctct ggagaaaaac tgatcctata tactggtggt gataagctga
    73321 tgcctgacgt aacaggatgg tcaaaagcag atatcatgaa gctggggaaa atcctcggta
    73381 ttgaagttag ttttgatgga gatggttatt gtgtcaaaca agaacttgct ccatatgaaa
    73441 aaatcactga agacaaactt agttttactt tagaagaata agaagagaaa taggagagaa
    73501 aagagcatgg aatggacaca agcattgatt cccattgtca gcagttgtgc aatgacaatt
    73561 gccgcaatgc cgctatttat tggttatttt caaatgaaaa agcaaggtca ggcgattcgt
    73621 gaggagggac caaagtggca caatagcaaa gccggaactc ctacaatggg cggcttagtg
    73681 tttctgatcg gctctatttt gacaggaatt tgggttggag cttggcaaaa acagctaact
    73741 cctactcttt tcatcttgct ttttgtatta gcgttatacg gagtaatcgg ctttcttgat
    73801 gattttataa aaatattcaa gaaaagaaac atgggactga actcgaagca gaaattgatt
    73861 ggacagattc tagggggaat catcttttat cttgtttacc gttctgaagg ttatccaggt
    73921 gtattgaatt tcttcggact agatctacct ttaggaatca tttatggtat tttcgctctc
    73981 ttctggcttg ttggattttc aaatgcagta aatctgacag atggcatcga tggattagtt
    74041 gctggcttag gaagtatctc ttttgcagct tacggtctaa ttgcttggca tcagcatcag
    74101 tatgatgtat taatcatttg cttaagtgtt ttaggaggtt tactgggttt cttcgtctac
    74161 aacagaaaac ctgccaagat ttttatggga gatgtcggtt cattagcgtt gggcggactt
    74221 ttagcggcaa tttctataat gctaaaccaa gaatggacat tgcttttgat tggtttgatc
    74281 tatgttatgg aaacagcaag tgtgatgctt caagttactt cctttaagct tacaggaaaa
    74341 cgaattttta aaatgtctcc aattcatcat cactttgaaa tgtgcggatg gtcggagtgg
    74401 aagattgata cagttttttg gttgatcagc attgtgactt cgttgatcac attatggatc
    74461 gtttggtagg agatgacggg aaatgaaaaa aatatcaaca tatgaaaata agaaagtgct
    74521 tgtcttagga ctcgcaaaaa gcggagtaag tgcggccaaa ttattacatg aattgggcgc
    74581 acttgtcacc gttaatgatg gaaaaccttt tgacgaaaat ccggaagcac aagagctgct
    74641 ttctttaggg ataaaagtaa taacaggtag tcatccaatc gaattgttgg atgaagaatt
    74701 ttcattgatg gtcaaaaatc cagggattcc ctacagtcat cctttagtag caaaagccca
    74761 agaaatgggt attccggtaa ttacggaagt tgagctagct tacgaagtag cggaatgccc
    74821 aattattggg attacaggaa cgaacggaaa aacaacgaca acaacgatga caggactact
    74881 actgaatgca ggagcagatc aaggaattgc acgtttagcg ggtaatattg ggtatccagc
    74941 aagtggtgta gcgcaagaag caaaatcaga agataaaatt gtgatggaat tgtctagctt
    75001 ccaactcatg ggaatcacag atttccgccc tcatatagcg gtgattacca atatctatga
    75061 agcacatatt gattatcatg gtacaagaaa agaatatgtc aaagctaaat ggaaccttca
    75121 aaaaaacatg acagaaaaag attatctgat ccttaactgg aatcagtcag aactacaaga
    75181 attagcgcaa agaacaaaag cacgcgtact gcctttctcg acaaaagaag tgttggaaga
    75241 cggtgtgtat gctgacgatt actcaatata ctataaaaaa gaaaaaataa tggaaatatc
    75301 tgaacttggc gtaccaggta agcataatgt agaaaatgca ctagctgcta tttctgtagc
    75361 aaaattgtat ggtatatcaa atgaagctat acgagaaacg ttgcattttt tccatggcgt
    75421 accacatcgt acgcaatatg taggagaaat ccaaggcaga aaattttata atgattcaaa
    75481 agcaaccaat attttagcga ctaaaatggc tctaagtgga tttgaaacgt ctaaggtcgt
    75541 gttattggct ggcggattag acagaggaaa tacatttgat gaattaattc cttcattaaa
    75601 aggaatcaaa gcaatggtcg tatttggcca aacaaaagaa aagttgatgg atgctggaaa
    75661 aaaagcaggc atcgagacaa tagtaacagc cgattctgta gaacaagcag ttcctttagc
    75721 attagaaaac agtacagatg gtgatgtagt tttattatca ccagcgaatg ccagctggga
    75781 tcaataccca aattttgaaa ctagaggaaa cagattcatg gaagctgtga accgattaaa
    75841 atagaaaaag tagaagcgag cgataaaaaa tgaaaatttt ggttacaggc ggaggaacag
    75901 ggggacatat ttatccagct cttgcctttg tcaattatgt aaagactcaa gaaccgaatg
    75961 ctgaattcat gtatgtggga gcaaaacgag gtctagaaaa caaaatcgtc cctgatacag
    76021 gaatgccttt ccataccttg gagattcaag gatttaaacg aaaaatttcc atgcataaca
    76081 tcaagacggt ccgattgttt cttaagagta tccgtcaagc aaaaaaaatc ctcagtgatt
    76141 ttcaaccaga tatcgttatc ggtactggag gatatgtttc cggagcggta gtgtacgctg
    76201 cagccaaaat gggtattcca acagttatcc atgaacaaaa cagtgtacca ggtgttacca
    76261 ataaattttt aagccgatat gtggatcgga tcgctctttc atttaaagat gcggcttcct
    76321 tttttcctga aaacaaagca gttcttgtag gtaatcctcg agcacaagaa gtagcagata
    76381 ctaaaaaatc agatattttg aaaacatttg atttggatcc agaaaagaaa acagtcttga
    76441 tttttggcgg tagtcaagga gcacttaaaa tcaatcaagc agtatcagtt tttttaagtg
    76501 aatatattcc ttcttcttac caagttttgt atgcttcagg agatagatat tatgaagaga
    76561 tcctaaataa aataaatcct gaaatacaaa atattagtgt ccagccttat atcaaaaata
    76621 tggcagaggt catggcttcc agtgatctgc tggtggggcg tgctggtgca acttcgatcg
    76681 cagaattcac agctctgggg ttaccggcag tgttggttcc cagcccatat gttacgaatg
    76741 atcatcagac taaaaatgca atgagtcttg ttcacgcagg agcagcaaaa atgattgcag
    76801 ataatgaact aacaggtgaa tcactaagtc agacagtcaa cgaaatcatg ggtgatgaag
    76861 aattgcaaaa gcaaatgtgc cgagcttcta aagaacaagg aatccctgat gcttcaaaac
    76921 gtctttatga cttagtaaaa caaataatca aaaaataaag gcggtggtct tagtgagtaa
    76981 gaaaaaagaa ccaaaaaaat tgtctcatcc gtcttctgat gaaaacaatt tgactccttg
    77041 gcaaaaggct aaccgaaaat atctggcaga acaagagatg aaaaaccaag agccaaaaaa
    77101 agaagacata acattagata cacccctttc agattctgaa gaagaaaaaa cggttcaaga
    77161 ggaacagcaa gaagaaagcc agtccgagaa aaaaatcgaa ttttttgaag agatcaagca
    77221 aaagaaaaac ggtggaccat ataacggttc ttttttgaac cggctgccca atttaaaaag
    77281 tcaacggcac aaagtactat ttcgtcggtt agctttgatc atcactgtat tgggtatacc
    77341 gctgattttt ttgatctatt atgtttctcc ttatagcaaa ttacaagcag ttgcagtatc
    77401 aggcaataag acagtcaaca gccaagaaat catctctgat acaaaattgt cattaggaga
    77461 aaatgtttgg ggacagtatt ttcatcgatc tacttatatc gatcgcctta aaaaagcaca
    77521 gccaagaatc gaaacagcaa atatacattt caaagggatg aatgaattcg atttggatgt
    77581 aacagaatat aaagagattg ctttgatcgc aaaaaacaat caatactacc cagtgattga
    77641 aaatggaaca gtattagatg aaaaagtagc aaatcctaca aaaaatctcc ctatcttgga
    77701 agagttcaaa gactctgcaa aaatcaaaga attaacaaag caatacaatc agttatcatc
    77761 agaattacaa aaagcaattt ctgaaatcaa gtacacgcca agagcaagca ataaaaatct
    77821 gatccaattg aatatgaatg acggcaatca agttattgta aatatcaata atcttgcgaa
    77881 ccaaatgaaa tattattcgc aagtagccaa agatatggat gaaaaaggtg tgatcgacat
    77941 ggaagttggt atcttctcgc atccttacgg tagcactcaa gaaacggaag aatcgggcca
    78001 atcggaagaa acaactgaaa gtgaagaaaa tgcggatcaa acaaacgaat caagtgaaga
    78061 ggcagaaacg caaaaagcac aaacacctgg atcgtctagc acaaacggat catctgattc
    78121 aaatgattca agtgaaacaa gtcaaataga agataatcca agtacaactc cgtcaagttt
    78181 aaatgaaaat tgataaaaca actttaaaaa gtaagaatgt actttctaaa aaccagtaat
    78241 ttatggtaga attggaagca gtgaatatat ctattaataa gtatatttta aaacggacgc
    78301 tagttgttcg cttgtatatg gaatagtaag taggagggaa tcccattcat ggcaaaaaca
    78361 ggaatgtatg taggccttga tattggaacg acatctgtta aagttgtcgt ggctgaatat
    78421 atcgacagcc aaatgaatat tattggagta ggaaacgcaa aatcagaagg gattaaccga
    78481 ggcattatcg ttgatatcga taaaacggtc caagcgatac aacgagcagt acgacaagca
    78541 gaagaaaaag caggtatcca gatcaaaggc gtaagtgtcg gtttgccagc aaacatgctt
    78601 gaagtagaaa attgccaggg aatgattgca gttaacggag attcaaagga aatcaccgat
    78661 gaagatgtca gaaatgtggc ttcagctgcc cttgttcgtt caatacctcc tgaacgtcaa
    78721 atcgtgtcaa tattgccaca agattttact gtcgatgggt tcgagggaat caaagatcct
    78781 cgtggaatga tcggcgtaag attagaaatg tacggtctgt tgtttacagg acctaaaacg
    78841 atcatccata acatacgtaa atgcgtggaa aatgccggat taatcgtcaa cgaaatggtg
    78901 attactcctt tagcgctgac tgaatcaatt ctttctgacg gagaaaaaga ttttggtacg
    78961 atcgtcattg atatgggtgg cggccaaaca acaacggctg ttatgcatga taagcaattg
    79021 aagtttacca atcttgacca agaaggtggc gaatttgtca ctaaagatat ctctattgta
    79081 ttaaatacgt catttaacaa tgcagaagcg ttgaaaataa actacgggga tgcataccca
    79141 gaacggacat caccagatga agaatttcca gtagatgtga ttggtcagtc agaaccagtg
    79201 aaagtcgatg aacgctactt gtcagaaatt atttcagctc gaatggaaca gattttcaac
    79261 aaagcaaaag atgcattgga ccaaatcgaa gcattagagt tgccaggtgg cgtcgtattg
    79321 acaggcggag ctgctagtct tcctggtgtt gtggacttgg cacaagaaat cttcggcgta
    79381 aatgtaaaat tgtatgttcc aaatcacatg gggctgagaa acccggtatt tacaaatgta
    79441 ataagtatcg tggattattc agcaaacttg agtgaagtgt atcaattggc aaaaattgct
    79501 gttacgggtg aaacctcagc agctcgtcaa atggtagttg aacaagaaac aacaaacaca
    79561 tatgagagct atgaagcacc tgaagaaaca atctacgatg agccggaacc aaaagagtcc
    79621 ggagaaaatg taaaaaataa aatcaagggt ttctttacaa atatttttga ttaattcatc
    79681 ctgggaggaa taagatatgg aattctcaat tgataataat atcaatgacg gcgcagtaat
    79741 caaagtcatc ggagtcggtg gtggcggtgg aaatgctgta aaccgaatga ttgaagaaaa
    79801 cgttaaaggt gttgaattca ttacagccaa cacagacgtg caagcattaa aaaattcaaa
    79861 agctgaaaca gttatccaat taggccccaa atatactcgt ggtttaggtg ctggttctca
    79921 gccagaagtt ggacaaaaag cggcagaaga aagtgaacaa tccttacgcg aagctttaga
    79981 cggtgcagat atgattttca tcactgcagg aatgggtgga ggaaccggta caggtgctgc
    80041 accaatcgtt gcaggtatcg cgaaagaatt gggcgcattg actgttggtg tcgtgacacg
    80101 tccattcact tttgaaggac cgaaacgtgg ccgttttgct gcagaaggta tcgctcgttt
    80161 gaaagaaaat gtggatacat tattaattat ctcaaataac cgtttattag aagttgtaga
    80221 taaaaagaca ccgatgcttg aagctttccg tgaagcagat aatgttttac gacaaggtgt
    80281 acaaggtatc tctgatttga tcacagcgcc aggttacgtt aaccttgact ttgctgacgt
    80341 gaaaacagtg atggaaaacc aaggtacagc attgatgggg atcggtgtgg ctagtggaga
    80401 agatcgcgta gtagaagcaa cgaaaaaagc aatctcctct ccattgcttg aaacatctat
    80461 tgatggagct gaacaagtac ttcttaacat cacaggcggt ttggatatga cattgttcga
    80521 agcacaagat gcttcagata tcgtagcaaa tgcagcaact ggcgatgtaa atatcattct
    80581 aggtacatct atcaatgaag aaatgggcga tgaaatccgt gtgacggtca tcgcaacagg
    80641 tatcgatgaa tcaaaaaagg aacgcaagtc tagccgacca gctagacaag cacaaatgca
    80701 atcacctgct caaaagactg tattagatat ggatcaagct aaaccaactt cttcagaaga
    80761 agaaaacagt tttggcgatt gggatatcag acgtgaacaa aatgttcgtc ctagagttga
    80821 tgattccaat tttgacaata tcgaaaaaaa agaatttgat acattcaacc gcgaagaaac
    80881 aaaatctcat ggcgatgatg aattaaatac gccaccgttt ttccgtcgta aaaaataaag
    80941 gagaggaaga gcacatgatt gctgacaact tgcagaaaat caagcaagaa attcaggatt
    81001 cgtgtgctct tgttcatcgt gatccgaaag aagttacatt agtagctgta acaaaatctg
    81061 ttgaatccgc tcaagctgaa gaattggtta gagctggcgt tatgaattgt gcagaaaacc
    81121 gagtagataa attattagaa aagaaacaag atttatttga ttttcctgaa ataaagtggc
    81181 atttaattgg taatttacag cgcagaaagg taaaattgat tgtaaatgaa attgattact
    81241 ttcatgcgtt ggacagttta agattagcag aagaaatcca gaagcggtta gagaaagaat
    81301 tatcctgttt tattgaagta aatgtttctg gtgaggaatc aaaacatgga atttcaccag
    81361 atgagctttt accgtttgtg gaatctttag ctgcctgcac aaaaatcaag gttgttgggt
    81421 tgatgactat ggcgcctaaa gaagcttctg atgagcaaat ccataaagtg tttggtacgc
    81481 tgaaagaatt gcgtgatctt gttcaagcaa aaggttatgc ccatgcacca tgtagtgaat
    81541 taagtatggg gatgagtcaa gactttcaaa ttgcgattga agaaggtgca acatttatcc
    81601 gtgtaggaac agcgctattc aaagacgaat aaaggaggaa caaaaatgcc gcttttaaac
    81661 agaggagcaa ttgctaattt tttcggatta gctgatgagg aagagtacga ataccaagat
    81721 tatcctgaaa caacaaaaaa ggctgtacag ccaactaaaa aaaatacaac acagaatcaa
    81781 tcaactcatt ctgtatctgc tgcgaatact catgaaaaac aaaaaacggc gacttcacgt
    81841 cctgtaacgc atgaaagtat tcagccggct gaaaagaaaa aagtaattga actacatcaa
    81901 tcacctacaa aaactgtagc gaaagaaaga acagcttcaa gaacctctac acaacctaaa
    81961 gcaaatcttg ctggaaaaat cactgtaatg gaaccaagag cttattctga agctatggcg
    82021 attgctaaac gaatcattgc tggagaagca accttagtga attttcattt agtagaagaa
    82081 aaacaagcga gaagaatcgt tgattttcta acaggaacag tttatgcact agatggagat
    82141 atcaaacgtg ttggagatga gatttttctt tgtacaccga ctgggatgga gattgacagt
    82201 tcaaccgctc aatcttttgc agatgcgaat ttgtttgatc tgtaagagga ggaactacga
    82261 tttatactat tgcactatta cttcatttac ttcaacgggc agcctatttc tatagcatta
    82321 tcttgatggt atatgcattg ctctcttggt ttccaggcgg gtatcaatca gggctaggac
    82381 gattattagc taagatctgc gaaccgtata tcagtttgtt cgatcgtctg cctttgagga
    82441 ttggaccctt ggatttcaca attttagggg caatcctgat cttgaactta gccgtacaag
    82501 gtttagcaca gatcgttata tggataactg tccatttagt ttattgattg aagcaacaaa
    82561 atctttattc tcagaataga taggagggga aaattttgat gcaaatgtat accagcactt
    82621 tcgggcagat gaacgtacat ttatcgattc ggtaggcgat tggattgaac aggttcaagg
    82681 acaatatgca ccctatctga ccgaatttct tgacccaaga caatcctata ttttagaaac
    82741 actgattcga caaagcagtg atttgcgttt catgttttat ggcggatatg aacaggcaga
    82801 aagaaaaaga tgtttgattt tccccgatta ttacgaacct gtagaggaag attttgaaac
    82861 agcattgtat gaaatccatt atcctagcaa atttgccagc ctaagtcatg ggaaaatcct
    82921 tggaacttta gtgggaacgg ggatcaaacg ctcttacttt ggcgatatca tctcggacgg
    82981 tgatcgctgg caagtattta ttgcaaatga ggtggatcat tttgttgctg cacaagtaac
    83041 aaagattgga aaggttgctg tacgcttgga accaatcaaa tacacagaaa tgattatgcc
    83101 gaaagatagc tggacacaag aaagaggaac agttagttcc atgcgactag acagtgtgat
    83161 ctctgagatt tataatattt ccagacagcg gtccaagcag ctgatcgaag ctggtaaagt
    83221 aaaagtgaac tggacagaaa atacaagacc tgattttgta cttgaactat tagatattat
    83281 ttcagtcaga ggttatggca gagtccagat ccaagaactt gaggggaaga cgaaaaaaga
    83341 aaagtacagg gtactgttcg gtgtattacg taaataaaat aaaaaggtgg tttactcatg
    83401 gctttaactc cattagatat ccaaaataag acattcccga caaaaatgcg gggatataat
    83461 caagacgaag tagatgattt cttagattta gttgttcgtg actatgagga attgactcaa
    83521 agaaatcgag aattagaaaa agcagtcaaa cattctgaag aaaaacttga gtacttcaat
    83581 gaattaaaag atgctttgaa ccaatcaatc atcgtagctc aagatacggc tgataaagta
    83641 aaaacaagtg caagcaagga atccgaagtg atcgttactt ctgcacaaaa caaagcagat
    83701 gagttagttg cgaacgctga aaaacgtgca catcaattaa caactgatgc agaagaaaaa
    83761 gcaagaaaaa tcttgacaga tgcaacagaa aaagcaagac agcttgcgac agaaactgaa
    83821 gatcttaaga aaaaaacacg agtattccat caacgtatca gcttgatgct tgagtctcaa
    83881 ttagaacaag tgaaaagtcc ggaatgggat gaaattttac aaccattctc cagctacgtg
    83941 actgacagcc atgaagtgat caaagaagtt ttagcaaaac agcttgacaa tgaaaatgat
    84001 actgatgtaa actcagacac aggagtcata gaagcaccta tgacggcatt tgatacacag
    84061 gctattgata tctcgatcgt gcctggtgaa aatgaaaacg agtagaacag aaaagcactt
    84121 tgttattctt aaagcgagcc gatgagagtg gaagttcggt aagacactgc atggtgaaag
    84181 atcctctact tgagacctgc ttttccgaaa ttagagtaag aagcagcggc tgacctcgtt
    84241 attggtcaca gagagtttgc actagataga tgcaactaaa tttgggtggt accacggcat
    84301 gttcgtccct tgcggctgaa catgcttttt tgtgtccgga aaacaaataa aggagtgtat
    84361 ggttgaatga aaatgaaaga aaccttgcaa ttaggaaaaa caaaattccc tatgcgtggt
    84421 aatttgccaa accgagaagg cgagtggcaa aaagaatggg aagaaaatcg aatctaccaa
    84481 aaaagacaag agttgaacga aggaaaacct agctttgttc ttcatgatgg acctccatat
    84541 gccaatggta atatccattt aggacattca ttgaataaaa tcagtaaaga cattatcatt
    84601 cgttcaaaat caatgtctgg ctatcgtgca ccatatgttc caggatggga tacacatgga
    84661 ttgccgattg aacaagtatt ggctaataaa ggcgtgaaac gtaaagaaat gtgcatggca
    84721 gaatacttgg aaaaatgtcg tgaatatgca ctttcccaag tagataagca acgagcagat
    84781 ttcaaacgcc taggagttgc aggagattgg gaacatcctt atgttacatt agatccttct
    84841 tatgaagctg cacaagtacg cgtatttggt aaaatggctg aaaaaggcta tatttacaaa
    84901 ggattgaaac caatttactg gtctccgtca agtgagtctt ctttagcgga agctgaaatt
    84961 gaatataaag atgtaaaatc tccatctatt tttgtagctt tcaatgtcaa agacggcaaa
    85021 gatattcttg atgaagatac agcttttgtc atttggacga caacaccatg gacattgcca
    85081 gcaaaccaag gtattgctgt aaatccaaaa tttacgtatg tattggtgga agccgatggc
    85141 cgtaagtttg tcgtagcgaa agatttgcta gaaacagtcc aatcagaaat cggttgggaa
    85201 aatgtaacag ttctaaaaga atttgctgga caagaaatgg aatatatgac tgcaagtcat
    85261 ccattctatg aacgtgaatc acttgtgatt ttaggcgatc atgttacttt agacgctggt
    85321 actggattag tccatactgc tccaggacat ggggaagatg actatatcgc tggtagcaaa
    85381 tataaactat ctgtagtgtc acctgtagac tcaaaaggat tgtttacaga agaagcacct
    85441 ggatttgaag gtatctttta tgacaaagca aatcctatga tcactgatct attaaaagaa
    85501 aaaggagctt tgctgaagct agatttcttt actcatagtt atcctcacga ttggcggacg
    85561 aaaaagcctg tgatctatcg ggcaactcca caatggtttg catctatcga taaattccgt
    85621 cagaatattt tggatgaagt agaaaaagta gagtgggtta tcccatgggg taaaacacgt
    85681 ttgtataata tgatccgtga ccgcggcgat tgggtaattt cccgtcagcg tgcatgggga
    85741 gtaccacttc cgattttcta tgctgaaaat ggagaagcaa tcatcacacc agaaacaatc
    85801 gaacatgtgg caaaattatt tgctgaacat ggatcaatta tctggtttga aaaagaagcg
    85861 aaagaacttc ttcctgaagg atttacccac ccaggttctc ctaatggcga atttacaaaa
    85921 gaaaaagata tcatggatgt ctggtttgat tctggttctt ctcatgaagc tgttttacgt
    85981 cagcgaccag aattatcatt cccagcagat atgtatttag aaggatcaga ccaatatcgt
    86041 ggctggttca actcaagtat cacgactagt gtggctatca atggtgtagc accatacaaa
    86101 tcagttattt ctcaaggatt tgctttagat ggtgaaggcc gtaagatgag taaatcttta
    86161 ggaaacatca ttgcaccaga aaaagtgatc aaacaatttg gtgcagatat ccttcgctta
    86221 tgggtatcta gtgtagatta tgaagcagat gttcgtgttt ctatggatat cttaagtcaa
    86281 gtggcagaag tatatcgtaa aatcagaaat acgatgcgtt tcttattagc gaatacagaa
    86341 gatttcgatc ctaaaaaaga tactgtttcg tacaatgatt tacgttctgt agacaaatat
    86401 atgaccgttc gattgaacca agtaatcaaa gaaatccgag aagaagggta cgacaaatat
    86461 aacttcatgc atatttaccg tacagttatg aacttcttga cggttgatct atcgtcattc
    86521 tacctggatt ttgctaaaga tgtagtttat attgaagcag aagatgatta tcaacgtcgt
    86581 tgcatgcaaa ctgttttcta tcaaacagct gtagctttga caaaattatt gactcctatc
    86641 attccgcata cagcagaaga aatctggtca ttcctgaaag aagaagagga gtacgttcag
    86701 ttaagcgagt ttcctggtta tgaagagttt gcaaaccaag aagaattgat ggatacctgg
    86761 actgctttca tggacttccg tgataatgtc ttaaaagcat tggaagaagc aagaaacagc
    86821 aaattgattg gtaaatcttt ggaagcaaaa ctaactgttt atccaaaaca acaagttcgt
    86881 gaaatgttaa aagctttgga tgcagatatt gcacaattat tgatcgtttc accagactac
    86941 tttgaagtta tggcagcaga tgaacaagtg ccagataacg ctatggtatt tgatgatgtt
    87001 gctattacag tggaaaaagc agacggggaa acttgcgatc gctgtcgcca agttcgtaaa
    87061 gatgtaggag tagatgaaaa acttcctcat ctatgcggtc gttgtgcaaa aatcgttgaa
    87121 gacttctatc ctgaagctgt agctgaagga ttcgaagaaa agtaaaaggg aaaagggggt
    87181 gtgacatgtt ctttgtcaca cccccttttg ttatcaatcg tttaattttc cacgttcacg
    87241 ataccagtta tctggttgcc agatccattc gaatccgtct ttttcaagta gttcgaaagc
    87301 tgctttaggt cccattgatc cagctttgta gttgggaaaa tccggttgtg tttggtccca
    87361 agcttttcga atgacatcca cgatatgcca agattgagcg acttcttccc aatgagagaa
    87421 gttcgttcca tcaccattca acgcatctaa tagtaatttt tcgtaagctt ctgggctatt
    87481 ttcaaccatt tctgcactat ttctaaattc caatttgatt ggttccgttt caaatccttg
    87541 ccctacttct ttcccattca aggataaaga aaatccttca gttggctgaa tatagatcgt
    87601 tagaacatta ggtggaagtg tcgtatcgtc acatggttca tcgacagatg ttttgaatac
    87661 attaacagga acttgtttga atacgatgtt gatccgagtc cctttttcag tcaaacgttt
    87721 gcctgtacgt acatagaaag gaacacctga ccaacggaag ttatcgatag tgaatttgcc
    87781 tgcgacgaat gtttcagtct ctgattgagc atccactttg tcttcttcgc gatagccctt
    87841 gaattgtaca ccatccaatt caccttgagc atattgcccg cgaacgaagt tttctaacac
    87901 ttcttcttcg ttataaatgc ggatagcttt caatgctttg atcttttctg tacggatttc
    87961 tttttcggaa aatgctactg gcggttccat tgcaagtaat gctacaacct gtaaaatatg
    88021 attttgcacc atgtctttaa gtgcgccact atgatcgtag tagcccccgc gatcttctac
    88081 accgaggttt tcgccaaaag taatttggat attgtcgata tagcgattgt tccattgagc
    88141 ctcaaaaata ttattggcaa aacggatagc tgagatgttt tggatcattt cttttcctaa
    88201 ataatgatca atcctgaaaa tatcttgttc tgggaatact tctctgattt gctggttcaa
    88261 ttcaaaagca gactggtaat cagaaccgaa cggtttttct atgatcaaac gattgaagcc
    88321 attttttgtc ataatatttt gtgatttcaa atgagaaacg atcgttccaa aaaattgagg
    88381 tgccatagcc aaataataga cacggttacc gtttaattga tagtgtccat ctaatcggtc
    88441 agacaattct tttaatgtct gataatgcgt tgaatcattt acatcatggg attgatagta
    88501 aaaatggctt gcaaaggtag ttgcttcttc atctgaagga ttcaatgcac ggattgtttc
    88561 tttgacaact tcacggtagt gctcatcgct ccagggacgg cgagcggttc cgattacagc
    88621 aaaatgctcg cctaaatttc cttttctgta aaggcggaac aaagacgggt acaatttacg
    88681 ctgggctagg tcacctgtac cgccgaatat cgtaaacaat acattttttt cattagacat
    88741 gtggatacac tcctttatat tttatcgaca aaaatcgtgc tggccgcctt aaagctgacg
    88801 gggattttct ttctatcatt ttggatagtg atcggtcctt cataagctgc gatgtcaacg
    88861 atctcatatt cttcgttgat attcaggtca atagtgacta agtaatccaa caattctttt
    88921 tcatcaagca ctcgtgcgat acgcactttt gtaccgacag gataggactc caatgtttgt
    88981 cggcgttctt catggacaac ttcctctttt ttaggaatcg atcctccatg aggacaatgt
    89041 tcaggatgat tcaaatagtt ttctaaatga tctgcaagat gttccgaagt cacatgttcc
    89101 aatacttcag catcatcatg gacttcattc cagctatagt ctaaatgttc aactaaaaaa
    89161 acttcccata agcgatgttt gcgaatcaga ctgctagctt tttgcagtcc gcttgcagtc
    89221 aattgtacac cttgataagg ggaatgttct acaagctctt ctttcacaag tttagaaatc
    89281 atttcactga cagatgcagc tgagacatct agactagata cgatttgttt attgttgact
    89341 ttcgttgtat ctccacctag ttctaaaatg attttcaaat aatcttctcg atttggtgtc
    89401 atattcgatc atcctttcat ggtaaaaaac catcattagt aagtgtaaca aaaaaaacgt
    89461 taattgacta tttttctaaa taaaaaacaa aggattttta gacgttttta caacaaaaaa
    89521 cgaaagatga tagagaagac tcattctttc gtttataaag gatatatata tacattggga
    89581 gggatctatt tttcagataa caacttatat gaagtgtctg cagattcgtc ataaagagtt
    89641 tgttcgggat aagaaaagat aagataaaaa ccatactgat cacgtacgac taaacgatat
    89701 tcatctattt ctaccacaga tgtgccaaga gactgaccgt tgatcaaaaa cgtgtaatca
    89761 gatgtaatct gtaattgttg tttttgctgg ctatcactaa agaaccatgt accttgatac
    89821 tttgagagtc cttctgactt ttccgcttgt tttttctttt tcaagtaaat aaaacttgag
    89881 agaacggtaa tgagtgaacc aagaaaatag atcatttttt ttatcaccaa atcactcctt
    89941 tatgagaaaa taatcgcata gacatattct ttcttcttta tttcattgta ccgaataaaa
    90001 gctaaaattt ctctaagact ttcgactggt ttttttactg tttttctaca aattatgata
    90061 ggatacatag taggaagaaa ggtgacataa tttgaagtat cagcaagtgg aaatagcttt
    90121 ttttattgac cgcccgaatc ggtttatagc acattgtatg aaaaaagacg gagaaataat
    90181 tattgcgcat gtcaaaaata caggtagagg aaaagaggtc ctgataccag gcgctgaagt
    90241 ggctattgta tttgctcctg gacctaaacg gaaaaccgcc tatgatctga ttgctgtaaa
    90301 aaagaagggt gactggttta atatcgatag tcaattgcct aatcggctgg caattgatgg
    90361 tattttagac ggcacgatcc ttttaccagg attaactggt ccatttacgg tatacaagcg
    90421 tgaagtaact tatcttcact ccaaatttga tatttattta gagacggtgg tcggacaaaa
    90481 agcatttgtt gaagtcaaag gtatgacact tgaaaataaa gcgattggtg cttttcctga
    90541 tgcgcccaca ctcagaggat tgaaacatat aggagaatta acgtatgccg cacaagatgg
    90601 ttatgccgct tatgtcttgt ttattgctca gttcgaacat cttcatctgg caacgatcca
    90661 tgaagaaatg caaccagcac tagctgatat ggttcgacat gcgcagcaaa gcggagttca
    90721 aatcctcgcc tataattgtc aagtatcggc agatgaggta actgtcaagc aggccattcc
    90781 atttgatgta gatatccctt ttgaagatcc tatacaatag aaagaaggta aaataatgat
    90841 caacttaggt attatcggaa caaattggat tactcatcaa tttgtccaag cagctttaag
    90901 cacaaaaaaa tatgaattga cagcggtata ttctagacat ttggaaaaag cacaggaatt
    90961 tggttctcat tatgaagggg atatcgaatt cgcaacagat ttgaagactt ttttcaatat
    91021 tactcatatg gacaccattt atattgcttc tccgaatagt cttcacttta gtcaagctaa
    91081 gcaagcaatt ttggcaggaa aaaatgtgat agttgaaaag ccagcttttt cgacgccaaa
    91141 agaaatggat gaaatcatcc atttggcaaa tgaacacaat gtgtattttt ttgaagcagc
    91201 aagaaatatc catgaatcag gttttaaaaa gattgccgat tacttaccat taaaagacga
    91261 gataatcggt gcaaatttca gctatatgaa atattcttcg cgctatgacc aagtattaga
    91321 tggagaagaa ccgaatatct tctcgactca tttctcaggt ggtgcattga tggatttagg
    91381 tgtttacctt gtatatgcag ctgttgcttg gtttggaatg ccaaaagaag tccattattt
    91441 cccaagaaag atttctactg gtgtagatgg tcttggatgg gggatcttac gttatgagaa
    91501 ttttgatgta tcgatccagc caggtaaaat cggtgattct tatttaccgt cagagattta
    91561 ttttgactca ggaacgctag tgatgaatgg agtcaatgca attgaacaag cacaatttca
    91621 tgatcgcgcg cataaagaaa tcattgattt ggcggtaaca gctgcagaaa atccaatggc
    91681 agatgaagca gaggattttg ccaatgtcat ggctcatccg aaagatccag cttggggatt
    91741 gttgtatgaa gagtggatcg agctagctag aaatgtgaac caagtgattt atgatttaag
    91801 aaaaaatggc ggcatcaaat tcgatgcaga taatgaggaa gatttttaat gaacgaattt
    91861 gtacaagtat ttcccgaaaa ttggcagaaa aaatatgagg ataaagggtt tatctcacct
    91921 tctcttattc aacgagcagt ttttcagcca ctaagtaata aacaaagtat agtagcggtt
    91981 tctcctacag gttcaggtaa aacactggct tatctttggc ctctactact aaacgtggaa
    92041 ccaggtgaag caagtgcgtt ggtcattttt gcttcttctc aagaactagc tattcaagta
    92101 gcagatgttg cacgtgaatg gggaaaagac aaagagttga aagtccaatc tttggtgggc
    92161 ggagccaacg tcaaacgtca gattgagggt ttgaaggaaa aaccagaaat cttgattggt
    92221 acaccaggaa gaatattgga attgatgaaa gcaaaaaaaa taaaagcaca tcaagtgaaa
    92281 acaatggtat ttgatgaagc agaccagcta tttgacgctg ggaacagcca aatcattgat
    92341 caaattcttc atcaagctcc aacagagtat cagctagctt ttttttcagc gacagcagat
    92401 cgttcccttg aaagcattga aaaaatcact gggaaaacgt ttgagacaat tgacgtgaca
    92461 gcagaggacg attctcgaaa aggactgaga cattactttt tacgtgtacc gatacgaaag
    92521 aaagatgact acttgagacg tctcacgcat atagaagatt ttcatggtct gattttcttt
    92581 aatcaactga ctgaattagg cgtaatggaa gaaaaattgc tgtatagagg tgtaccggta
    92641 ggaagtctgg cctctgatca gaacaagcta ctccgaaaag cagcgctaga acaattcaaa
    92701 aagaaaatgg tcagagcact tttgaccaca gatgtggcgg ctagaggttt agatattaca
    92761 ggtcttcctt atgtagtgaa tgcagaagtt ccgttaagtg aagaagctta tttgcatcgt
    92821 tcgggaagaa ctggtcgaat gggtaatgaa ggaatagtaa ttacactcgt acaagataat
    92881 aatctaagag atttaaaacg gcttttacgt ccatcaaata taacacttga agagattttt
    92941 ttatacggag gtaagctgca aactgagcag ccaaccaaag aagatgcagc tcctgcagta
    93001 aataaaaagt atgcgaaaac tttttctgga aaggagcaga acccagaata taacaaagaa
    93061 aaaataagaa aaaaagttaa aaataaatca aaaaaagaga gaaataaagg agcaaggcgc
    93121 aaataagcgc ctttttatgc tatgattatg aaaacgggaa caaaattggt tgccagagga
    93181 ggggttatgt gaaagaacgt caagaagaga tcttgcagct attgacagaa aaccaacaag
    93241 gattgacagc aagtgatgta gctgagcgct taactatcga tcgaagcaat gcaagccgat
    93301 atttaagtga actatacaag gcccatcata ttgtaaaaac cgctggccga ccagtcgttt
    93361 actctttgcc aacggaaaag tcaaaatctg atgaagtgca tgtcgactct tctacgcaag
    93421 tgacttttga aacactcgtt ggagaaaatg attctttaaa agtcagcata cagcaggcaa
    93481 aagctgcgat tctttatcca ccgcgggggt tgcatacgat tatttttgga gaaactggta
    93541 cagggaagtc gatgtttgct gaatgtatgt atcattttgc aatcgattca gagatgcttt
    93601 ctgcagatgc gccatttgtt tctttcaatt gtgcggatta tgctcaaaat ccgcaactgc
    93661 tctttggaca catctttggg atcaaaaaag gggcttacac aggagcagct caagatagtc
    93721 ccggtctaat agccaaagca gacggcggta tattgttttt agatgagatc caccgtttac
    93781 cgccggaagg gcaggaaatg ctgtttactt tcattgataa aggtatttac cgtccgcttg
    93841 gagaaagtgc acaagtacat gaagcatctg ttcagatcat tggggcgacg actgaatctt
    93901 cagaaagttt cttatctacg ttcaatcgac ggattcctat ggcaatcacc ttgccgaatc
    93961 ttgcttcacg ttcactggat gagcgttatg aaatcatctc tctttttatc aaacaagaag
    94021 cgaatcgttt gaatcaacgt atcgatatcg aaaaagaagc gattcttgcc ttcatgcttt
    94081 atgatgcgga aggaaatatc ggtcaagtga aacgagactt gaaactagtc tgtgcaaaat
    94141 cttttttaca ttaccgtact catcatgaga aaaagctaat cattcgaaaa gaagaacttt
    94201 cccttcaagt acaaaaagga ttactgaaaa tcaaggaaat accggaacgt ctcgaccgat
    94261 tcatggacag caaaagtcag tatttgacat ttgaaccagg atttgctgat gttgtctggt
    94321 cacaagatcc agaacgaaac atgcaggtct ataacgatat tgaggaaaaa gtcacttctc
    94381 tttccgaaac cggtgtggag aacattgatc tagagaccct catttcaaaa gatgtggatg
    94441 cttatttcca gacatatgtc aaagaattga ctaaaagttc gattcccaaa gatcttttgc
    94501 cagatgaaat ctggcggtta accaatcaat tgtatgatgt ggctgaaaaa cggttagacc
    94561 gtatttataa tgaaaaagct cgttttgctt ttgctttgca tctgcaaagt acattggatc
    94621 gtgtgagaga aggtcatatg atcgtccacc cagatttgaa taacgtacgg aaaaatttta
    94681 agagggaatt ccaggtagca atcgatcttt caacgatcat tgaagaagaa gaacaagttg
    94741 agattccttt tgatgaaatc ggctttatta gtatgtttct ttctatcaat ctaggagaaa
    94801 gtgagcctgt taaagaaaac aaagtagatg ttctcatatt gatgcacggc agacagactg
    94861 cttcaagcat gttggagatg gcacaagaac tattaggaac aaaagtaggg aaagctttta
    94921 atatgccact ggttatggaa gttcaaacaa tgtatgaaga agtgttacaa tatgtcaaaa
    94981 actatcaaga gcatttgacg aatggcctac tcttgttaac agatatggga tcattaaaca
    95041 ccttcagtga tttgatttat gaagagactg gcattcggac gaaagctatc acgatgacaa
    95101 gtaccatgat tgtgatagaa gcgatacgga tggcaagtgt tggaagaagc ttagaagata
    95161 tttatcaaaa tatccagctt tcctttgaat cgatcgtacg tgatcagttc aaagcggaaa
    95221 agtctgaaac tttacagcgt aaaaaagccg taatcgtgac atgctttact ggtgaaggag
    95281 tagctgccaa attatatcag cgtattatgc cagtgattaa tcaaaataag gtagaactga
    95341 tccagatgca gtttttagaa cgtgaatcat tcaaaaaaca catcgatgcc ttattggaag
    95401 aatatgagat caaagcaatt gcgggaacag ttgatgttga ttatcaaaat atcccatttt
    95461 tttcagccta tgacgttttt gatgatgaaa aactaaatat tttaaagcgt atagctgatg
    95521 atgagatccc gacagctaaa attgtcgatt cacttgctgg atcattaagc gatgtctttt
    95581 ctattgatga actgatccgt tcattgcaaa agacagttca gcagatccag accgatttgt
    95641 cgattatcgt ggaacctgga gtagatactg gaatcgttat ccatttagcc ttcatgttag
    95701 acggattgat caaacaagaa agccatcggc aatttgagaa actgtctatt ttctcaaaaa
    95761 tttatcgttt ggaaatggat atcgttcggg caaacttgat ggcactagaa cgaaaatatc
    95821 aggtaaaaat tccagaagat gatatcgcat ttcttacaca aatgtttctt gaaaataaaa
    95881 taaaaaaatg aacacactaa tcatactgtt tacacactaa acatctgtgt gcgcactata
    95941 aaaaagagct aaaaagcatg aaaacgctat ttcagctctt ttttttattg gcatgcttct
    96001 tgcgttatat aaaagtgtaa aaaaataaaa ggagtgttaa aaatggcaaa aaaaacaatc
    96061 atgttagttt gttcagcagg gatgagtacg agtttattgg tcacaaaaat gcaaaaagca
    96121 gcagaagaaa aagggatgga agccgatatt tttgcggtct ctgcctcaga tgcagataat
    96181 aatttagaat ctaagaatgt cgatgtatta ttattaggtc ctcaagtacg tttcatgaaa
    96241 gctcaatttg aacaaaaact tgcgcctaaa ggtattccat tagatgtcat caatatgcaa
    96301 gactatggca tgatgaacgg agaaaaagtt cttgcacaag cagaaaatct aatgaaataa
    96361 atcaagtatg cagttggggg tataacaacg tggaagatca acaaaatcta gaagccatca
    96421 tggggttaat catgtttggc ggtaatgcaa agagcgatgc aatggaagcg attgcggctg
    96481 ctaaaatcgg tgattttgag ttagcggata ggaaaatcgc tgatgcagaa gaatcactta
    96541 tacaagcgca tcatgcacaa acagacatgt tgacacaaga agcacaagga aatcatatgc
    96601 aagtgacatt attgactgtt cacagtcaag atcacttaat gacatctatt gcgtttactg
    96661 atttagcaaa agaaatcatc gaactttatc gtcgcgtata cagcgaataa atacaacttc
    96721 ttttttgaac ggaagaagaa aaatttttga acggattttt tattttgtta taaggagaac
    96781 tctctttata taaaaaactt ataggaggaa gtaaaaaatg aacggactat caagttggat
    96841 ggagaaatac atcctgccgg ttgccgcaaa aatcggagcg caaaaacatt tagttgcttt
    96901 gcgtgatgct tttatcggca tactgcccgc aacaatggcg ggatcagtcg ctgtaatgat
    96961 caatgcaatt attcgtgatt taccgcaaca gtttaacagt acctatgctg acagtttagc
    97021 agcagacaaa ggaatctttg ccgtattgaa tgtcatcatc ggaatcaatg gttttgtctg
    97081 gaacggtaca ctagcaatcg ccggattgat ctttgccttt tcttgggggt ataatcttgc
    97141 ccgagcttat ggagtaaatg atctagctgg ggggatcgtt ggtttagcta ccttgattca
    97201 aggtatttcc tttggtccag cattatcagc agcattagat gtgaatgttc cttcaaatgt
    97261 cgcagatgca atcaatagtt ctgagattgg tgcaacgatt gcagatggca cactgtcagt
    97321 tggattatgg ggttggctaa aactagatca tttgaatgga aacgcttatt ttacagttat
    97381 gatcatggga gctatttcag tcattatttt ttgtaaattg atgcttgcca acattacgat
    97441 caaaatgcct gattcagtac caccagcagt atctaaagca tttgcagcca ttttaccagc
    97501 gacgatcgct ttatacgtca ttgctattat caattatatc gtaggtcgtg tagctgatgg
    97561 gcaactgatc attgatttgg tgcaaaaata tattgcagaa ccattcctag gattatctca
    97621 agggttggga gcagtattga tcgtcacagt atttgttcaa gtattctggt tctttggtat
    97681 tcatggatca aatgtattgg caccagtgct agagggaatc tggggacaag cacaactaat
    97741 caatattgat attttccaaa aaggttataa cggaaaaact ggtacaccag ccgtgttaga
    97801 tgcaatcgaa gatggaaaag cttatatgtg ggtccgcgga tcgttcgatg cttttgcatg
    97861 gtttggcgga tcaggcggaa cgatcgtctt actgatagct atcttgattt tctctaaacg
    97921 tgcagattat ctaacagtag ctaaattatc cattgggcct ggtatcttca atatcaacga
    97981 accagtgatg tttggtctgc caatcgtatt gaatgcaatc atgtttatcc cattcttgat
    98041 tgctccagta gtagcaacag caattggatg gacagctact tatcttggcc tagtcgctcc
    98101 ggtatcgcag caagtcacat gggtagtacc gccgttctta ttgtcattct tagcaacagg
    98161 agcggattgg cgggcaccga tcgtaacatt agtatgtatg gtcgtgactt tcttgatttg
    98221 ggcaccattt gtcatctctg caaacaaaat ggaccctgcc gcaggcgaac aacaataaga
    98281 tgaacgtgag gagcgggacg ctttaagttt cgttcctcat aatgaatttt cgaggaggaa
    98341 ctgaaatgat tacaattgcc agtgcaatgc aacaagatga aatcaaagaa ttgttagaag
    98401 gatacaatga agaaggaatg acttttacat ttaaagaaaa acaaggaatc aagctgttct
    98461 ttgaaacaag tgcagaagat ccggaagttg cggctaaaaa agcaaaggaa ctaatcaaag
    98521 cacagccttg gggaacagtc ctttattttc aatcaacagc tgtttagaaa atggtttaaa
    98581 aagataggat ggttgagatg ataaaaaacg gtttattttt atgtagtatt ggttctttga
    98641 tcgtgttgta tagtttgaat ccacattcgc aaaggtatga tttgtatagt atggtcacag
    98701 gtctttttct aacaggatta ggaatctatt tcttcatgaa ggggaaaaaa agagaagaag
    98761 caaaggagaa aaataactaa tggaaatcac gaaaaaatta aatattccag catcgttttt
    98821 ttacgataaa gttatggact ctgtcctttt cgatgtacgt aaagcgaccg gcaaatcagt
    98881 aactagaaaa cagctgaaaa atttggagta cgtcaaacaa ttctcgcaaa ataaccgggc
    98941 tcgcataaaa atcgaagaag tcattgaaaa ccagtcttat aagtttcgta catcgacaac
    99001 gaagaatgaa ttcgtcgttc attatcaaat caaaccattg gacgattcga cctgtgaggt
    99061 tcattacaca gaaaaaatgg agtcttatgg catgcttcaa aagttgaatg atatgctttt
    99121 aggaacaatc ttgatgtatt ttaaacggag acgtttcaaa aaaatgctag atatgatcga
    99181 agcaacgtat taaatcaatg aaacatggta ctatttagtt attgaaaaat gaagtaagct
    99241 agaaggaatt tttcatagga agatagatct ttcctgcgaa tcctcactag cttttttgta
    99301 ggaaggggca gcaaaatgac aaacaaagta agagagctag gtgtatcttc gattgaggaa
    99361 atgtttgatt tagccactta tgcatttaat ggggcagata cacctgaaag gcgagaacgt
    99421 tttcgtacac ttgcggagaa ttcttggaat tacggatttt ttgatgagga ggatcggcta
    99481 acaagtcaag tcatggcgac cccttttcca gtgaattttt acggacaaga gtacctaatg
    99541 gccggcattg gctatgttgc ttcttatcca gaagcaaggg gacaaggcgg gatcaatcag
    99601 atcatggaaa agatccttga agattgccgt gatcgtaaag taagcttatc ttatctggcg
    99661 ccattctcct atcccttcta tcggcgctat ggctatgaac aatcatttga taaaatcagt
    99721 tatcaactaa acagtcgtga tgtgccgttt atcaaaaaaa aatctggaaa aataaagcgt
    99781 atggattttg aagatgcaaa agctgcaatc agaagaattt atgaacagat gccggaaaac
    99841 caacgagctg gtctgaagcg cgaagactgg tggtatacgt ataaattcaa gcaaaaaggc
    99901 aattaccagt ttgctttgca ttttgatgat aatgaggaag caacgggata tatcgtttat
    99961 cagcttgcaa cgtcttcctt tattattgcg gagtggggat ttttggatca tgatgctttt
   100021 tgcagccttg ttcgcttcgt aagttctcac aatggtgctt ttgaaacatt tgaatattca
   100081 tgcggctacg gcggtaatga tcaaaattat ctattagaaa atccatttgc ttctgtaatg
   100141 atcacacctt atatgatggc gaggatcgta gatatttctt tgtttttgga aaattatcca
   100201 tttaaaaaga gacaagctgc atttgcccta caaatagaag aagatcatta tgcgaaatgg
   100261 aatgaaggaa tcgtggaagt aacaatcgaa aatggaaaaa atcatctctc aaaagtagaa
   100321 caaacaaaac tcccaatcgt tcgaggaagt atccaacata tcacgcagct attattaggg
   100381 tatcgtaaag tggaagagtt ggtattccaa gaaagaatac aggtgacaaa agaatatgaa
   100441 gaaacgttaa gctcaatctt gccacagcaa cagccaattc ttaatgacta tttttgataa
   100501 aaaacgggtg atgacaatat ttttgtcacc acccttttgt ttttcatttg gcatttgaag
   100561 gaaaatgtta aagtaaatcc tcttttttcg taaatttgaa ttttttgttt tcttttgttt
   100621 tagggttttc ttttttgtgg tcttggattg cttctttcgt aatcttttcc cgattttttt
   100681 tagatgaatc taagcgttct gcgtatactt tttcttttgg cttatcattc attggaaagg
   100741 acctccctac attatttcat tctacctcta gtttatcatc tgttaaggac tagtggaaac
   100801 gttttgccta acttataagc tgattttttt agcagataag cttgcaagta aaaaacaaac
   100861 aagctacaat tgatttattg aaattgttcc tgtagctcag taggatagag caatcgcctc
   100921 ctaagcgata ggtcgctggt tcaattccag tcaggaacgt ataaataacc cctgtatcct
   100981 ttgcggtaca ggggtttgtt ttgtatttgt gccaaaaatg tgccaaacta gttatcattt
   101041 ttatataaac tatcgaacac agtattgatt ttttctttat cctgatcttc aagctctcga
   101101 acaatatgaa gataagtaga cattgtagtt tctaaactgc tatgtcctaa acgtttcgat
   101161 acgctaagta tatttactcc ttgataaagt aaaatagatg catgtgtatg ccttagtcca
   101221 tgcaaagtaa attgcttttc aatccctaat tcttttaatt ttttgcgcaa atatttgctg
   101281 acggcgtttg atgaaactaa tccatttttt aagttgaaaa aaacaaaatt atgagggttt
   101341 ttgatttcaa aattctcgaa taattctttt tgattgattt taaacttttt taagagatca
   101401 atcgtatgtt tatcaatgga aattttccta tttgaagttt cgttttttgt ttttccccat
   101461 tcatttaatt tataattcca tgttttatta atagtgatga tttgatcttc gaaatcgata
   101521 tcttcccatg ttaatcctag aagttcagca aatcgcattc cagtggcacc agcaactaac
   101581 acgagcatag gagaagagta ctgcgcagaa aggttttctt ctacgagttt cattaaagat
   101641 ttaaattgat cataatctaa atatttatct tcttttggct tcaatgaatc ttttcctttg
   101701 attactgctt ttctagttgg atcaaacgga attaatcctt cttctacggc atctttcaac
   101761 gacgctctaa tatggttatt aaacttaata acggtagatt ttacatggtc tttagcatac
   101821 ttatttaaaa agcgttgata tcccactcta tctaaatcag aaatcaatac cgctggcata
   101881 tatttcttta tgttcattaa cgtatcttcg tattttctat aagtgatagg agatactgtt
   101941 ccttctttat aaagttgcat ccaatcctca aagtaatctg ataataatag atttttgcga
   102001 tcccctttaa ggcctttgtt caagttatat tctaattcgt tggcggcatc ttttgcttct
   102061 ccttttgtct taaatcctga ttttcttatc ttcgtgtatt ttccgtcatc ttttttgtat
   102121 gaaatttcgt attgccaact atttccacgt ttgactaatc ttgccataat tgaatcagct
   102181 ctctttctct gatacaatag gaactataaa gaagcccatt gtttgggttt tattattttt
   102241 tgcacatcct ttttgcttgc cggcgcaagg atgtgctatt tgtcgtttta atggtataat
   102301 tggatgtgta ttagatcatc caatcagagg tgtttattat gattaaagtg atttttaaaa
   102361 gaataactga acttccagag tttagattat ttgttgatta ttggtatgtc tggtttttta
   102421 ttgttgcatt gctgataggt ctagatgtca tattagaaag aaaacttaag taagagttga
   102481 gttaataaat tgaattccta aatgagatat tttgtagccc atattttgtt tgccgacatc
   102541 acctaatact atggagctaa tcgttttttc taacagacca aaatcagata atctatttaa
   102601 gctaccatct attagctctt gtgaatagcc agacatgctg atatttccag tgaaattttc
   102661 gtttccacga ctcattaagc atgctaacaa ttgaatctca atcgatgtta attgattcag
   102721 tacaagaaga taatactcct cgttatccca tgaagcgttg ttaattcgaa gtaaacaatt
   102781 cttataaaga tttttataca tatctatttt attttgtgcc tttgattttt ctacctcgtc
   102841 atttatccct tcgaatattc caatgagttg gtccttgttc tctaagttga aaacatcttc
   102901 tggaatttga tcgcgaatgt tttctaatga ttcgtttaaa tttttgtaga atttctcgat
   102961 gcgtttgaaa cgcttctcgt ttttagaccc aaaataaagt gactgcacaa cgccaccaat
   103021 ataaggaatt gctccaatac cgccttcaac tattaattca agatattctt ttttggttag
   103081 tttttcattg ctattatcca tagttacctc ctattttgtc atttccttta caagcattgt
   103141 gactcctgat ggcactcttt tgtataggtt ttattattgt gcacaatcta actcttagtg
   103201 gggcgtggtt catttatttt ttacttactt tactattaat catatcccat tgagcatagg
   103261 atttttctat gttcgatcct cttgaactaa tttctcctgt aaaagttact ttatcgccct
   103321 ttgtaaaggt atcagcattg tttaagtcct tcgcaaaaat tacatatgaa actttaggtg
   103381 ttgcagaaat atcattccaa cttttatcat cgtactcttt gtctgctata atggctattc
   103441 tagtagtcat tgattcgata acagttcctt caaaagtata tgttttacca ctaatatatt
   103501 tagtaaaagc tgtattttgc tcagtagctg gagtaataga ataataacta tctaagaaag
   103561 caccccagtc atgattattt gtctctaaaa attcttcaaa ttgagttagg cttttattgc
   103621 tgctgttaga tgtagtagtt tgagtatcag atgatgagct ttcctgtttg ttattgtcat
   103681 ttgcctcgtt tgatgaggaa agcgagaaac ctacggtagt aaaaataatc ccgataataa
   103741 ggagaatcat aggtgttttc ttatttgttt ttttgataaa tcttacaatt aacatgatta
   103801 aacctataat aaataaaaca ataccagtaa aaccaaatat accgtccatt aatagatcct
   103861 ctttctcttt tgatattgaa tattataaac caagcaattc ttttttctta aaatcgaatt
   103921 cttcttgatt aataatccct tcatctaaca actctttata ctttttaatt tcatctgcac
   103981 ttgaaatttg tgtttctttg gaattattat ctaatataga ttgttgcttc tctatatatt
   104041 tttttaaatt ttccatttca ttccaatatt tttttgtaaa cataacggtg ttttcatctt
   104101 tcgtggccgc taatatacct ccgcgacttt cgtttccgcc tagcaaggta aattgtatat
   104161 aaccattact catacctggt ttttttaatt gtacggctga tatattttta aaggggatag
   104221 ttttttctcc tttaatacct tgattaacta aatttataaa tccttttcta ataattgaaa
   104281 tagaatcatc agttacttta atcaaggttt ttcctggaga ttttattaaa atctcttttt
   104341 ccattttttc ttcctcattt ctgtgatatg attttttttg tagaagctca tatatgagga
   104401 aagagcccgt gttgcagcac gggctttttt aatgttttgc tgaaatcggt ttttttaata
   104461 attcttgatg tattcataca tattgccttg cgtaagaata ttttttctta aaatagcatt
   104521 ggcagacagc ataacaagtg tatctgagct tattctgaat agaataatac tccataaatt
   104581 tttcgagatt aaactgagat tcatcagtca gttcgttctc aatatagata tttaataaaa
   104641 ttagaatagc tattttatct gcttctgttt caaattttga gtgaaaagtt gtagaagtat
   104701 cgtacaaaac tgaaaattca aaatgagagg cgctgaaatg tgcaagttca tgagataaat
   104761 gaaaggcttc tgcagtttca ccgtatagat tttcattcaa aaaaatgatt ctgggttttg
   104821 gatagtagaa accaggctct ttcatctcca tataaactac tttcaaattg tattcgctca
   104881 acatttcttt caatttcaaa tacatacaaa ccatcactcc aactattcat tttcctctaa
   104941 agctttagca attgcaatcg ctttacgcat tgtctcctta gatatttctt ttccatcaaa
   105001 agaaaaaaca gtatcgtctt ctgataaatc cacatgttta ggggtttctc tttcttctct
   105061 acctagaagg tagtctacag agacatcgaa atagtcagca atccgactta attcatctga
   105121 attaggagta ttatttttcc actttgctag ataaccgtta gaatatccaa aattaatttc
   105181 taactgccgt atagatatct ttttcctctt cgccaagtct tttattattt cataggtatt
   105241 catcgataaa acaacctttc taaatgttta caaaaaaagt ttagaaaaat acgcagaaat
   105301 aatttgacta attctgagta atgagctata ctatatcttg taaacagatt taacaactaa
   105361 aaagacaaca aaaaacacta ttgatatgta aatgcagacc gccaagaaag ctttaaaatc
   105421 aatgttttta tgtcttattt aattatgctc ttagtataga gtattactca gatactgtca
   105481 attgaattta gaaaaaagtt gttaaatttg tttacgaata taaaagaaag gaatgagaaa
   105541 tatgaacaca ccgcaaattt ttaatttcga acaaaacgaa gttcggacaa ttttagtaaa
   105601 tgatgaacca tattttgtag gcaaagacgt tgcgagtgtt ttgggttatt caaacactaa
   105661 agatgctttg tcgcggcatg tagatttgga agataagatg gggtcgcgaa tcacgacctc
   105721 aggtcaatca agagagatga caatcatcaa cgaatctggt ttgtacagtt taatcttaaa
   105781 atcaaaactt ccctctgcca aaaaatttaa acgttgggta acaagtgaag tgttgccagc
   105841 aattagaaaa catggaggtt atctaactcc agaaaaagta gaagaagctt tgcttaatcc
   105901 agatacaatc attcaattag caactcaact aaaagaagaa agaactggaa gattaatcgc
   105961 agaacaaaag attgcagagt acgaacctaa aatctcctat ttagatagca tattatcttc
   106021 tacagattca gtaacaatta gtcagattgc agcagattat gggatgtctc cacaacagat
   106081 gaataaatta cttcataaac taggtattca gaaaaaagtc ggtaaccaat ggttattgtg
   106141 caaaaaacac atgaaccaag gatacacaaa atctcataca actgagatcc cgaaagccga
   106201 tggtggcact aaaattgtaa tgaataccaa atggacacag aaagggcgtc tatttatcta
   106261 cgaattacta aaaaaagaag gatattaccc tcaaatggat ttagaggaaa ttggttagaa
   106321 aggagtttta gtatgactga cattgcagaa atcactcaac gagatagaga aaaaatcaaa
   106381 gaatatgtcg aaagttcaaa gttcttaact tacaccatgc ttgctgaaag atttggaatt
   106441 agcaaaagct acttatcttt aattttaaac ggtaaaaaga cttctgcaga agcaaacaga
   106501 attatagatt cgattatcac tatgtacgaa ttgtaaaggg aggaacagct aatgcaatat
   106561 ctagaagcaa aaatcccaat tccagaaggc tatgtaatta tctcccaagt ggattatgag
   106621 gagttaaaaa aagctgatga tactggtaga tggatgacgt tgccagaagt gctagaacgg
   106681 attaacagaa aatatgattg gtttacttct agagttttaa agaacccaag atatagaaat
   106741 attatcgata tcgagaaaaa caaaaatgga tttgtctatt atccagttga aggaagagac
   106801 acatatctat ttttaagaag taaaacactt gaatttttag aaacaaattt ttcggaaatc
   106861 ttaaggaggc aagcggatgg gaaaatttaa tagagcgcta gtgttcagcg caccgctaat
   106921 catctacgct ttaggact
//
LOCUS       DBBGSZ010000007       104587 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.007, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000007 DBBGSZ010000000
VERSION     DBBGSZ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 104587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 104587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..104587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.007"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            158..2692
                     /gene="secA"
                     /locus_tag="ACIZE5_000706"
     CDS             158..2692
                     /gene="secA"
                     /locus_tag="ACIZE5_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HGC6107871.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            2818..3919
                     /gene="prfB"
                     /locus_tag="ACIZE5_000707"
     CDS             join(2818..2889,2891..3919)
                     /gene="prfB"
                     /locus_tag="ACIZE5_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HGC6107872.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            4024..4710
                     /gene="ftsE"
                     /locus_tag="ACIZE5_000708"
     CDS             4024..4710
                     /gene="ftsE"
                     /locus_tag="ACIZE5_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HGC6107873.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            4703..5587
                     /gene="ftsX"
                     /locus_tag="ACIZE5_000709"
     CDS             4703..5587
                     /gene="ftsX"
                     /locus_tag="ACIZE5_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HGC6107874.1"
                     /translation="MIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFMAVI
                     MNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELKKIQ
                     NEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEKAADLKNVSRSDYGGASSDRIF
                     QIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFF
                     LEGGWIGLIGAILPILIITFGYAWFYQLINPSLLRSHYSLIHPENIVWKINLLMVGIG
                     VIIGSLGSIISMRRFLKF"
     gene            5739..7187
                     /gene="cls"
                     /locus_tag="ACIZE5_000710"
     CDS             5739..7187
                     /gene="cls"
                     /locus_tag="ACIZE5_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGC6107875.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDTLGE
                     EVREALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPEFFPTIHSTGDMAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEVYENRGMMIKMKEGLARLISPLL"
     gene            7524..8381
                     /locus_tag="ACIZE5_000711"
     CDS             7524..8381
                     /locus_tag="ACIZE5_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HGC6107876.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQAENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            8496..9416
                     /gene="pstC"
                     /locus_tag="ACIZE5_000712"
     CDS             8496..9416
                     /gene="pstC"
                     /locus_tag="ACIZE5_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGC6107877.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            9416..10300
                     /gene="pstA"
                     /locus_tag="ACIZE5_000713"
     CDS             9416..10300
                     /gene="pstA"
                     /locus_tag="ACIZE5_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGC6107878.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            10315..11121
                     /gene="pstB"
                     /locus_tag="ACIZE5_000714"
     CDS             10315..11121
                     /gene="pstB"
                     /locus_tag="ACIZE5_000714"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGC6107879.1"
                     /translation="MKKYNWNETNVITMPKDKEVALYTNDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYKDVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            11137..11895
                     /gene="pstB"
                     /locus_tag="ACIZE5_000715"
     CDS             11137..11895
                     /gene="pstB"
                     /locus_tag="ACIZE5_000715"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGC6107880.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWEDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            11908..12585
                     /gene="phoU"
                     /locus_tag="ACIZE5_000716"
     CDS             11908..12585
                     /gene="phoU"
                     /locus_tag="ACIZE5_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGC6107881.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            13149..13841
                     /locus_tag="ACIZE5_000717"
     CDS             13149..13841
                     /locus_tag="ACIZE5_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HGC6107882.1"
                     /translation="MLLIGGKQGVFALGSLIINIVLLLLLLLLFTKTEGISLLNIAIL
                     FVVIGIIVSILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYL
                     TRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKQQPKISAKQLWLSGRQVGRDVI
                     GSMANILLFVYISGAIPSLLLYLGNQWSFKETVERHLSLELLRVIAGSLGIVLSIPIA
                     VLFFLAVRRLKK"
     gene            13838..14605
                     /locus_tag="ACIZE5_000718"
     CDS             13838..14605
                     /locus_tag="ACIZE5_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HGC6107883.1"
                     /translation="MNVLIILVGIFAISVLFVGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILVLSIIGFLLIAVVILFFINGYNLKMRAAFASILIFLFCFLLLIPITDFLAI
                     QGFTSIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     MSFNQLRHASFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDISFQQIINEKSFVL
                     EYTMAILTTLAALLVLPLTCVTTAYLFTKKKEHLKME"
     gene            14705..16273
                     /gene="liaX"
                     /locus_tag="ACIZE5_000719"
     CDS             14705..16273
                     /gene="liaX"
                     /locus_tag="ACIZE5_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HGC6107884.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDELENGEEKISEPVDPKEKERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEATGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSDDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVNQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATPENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDSIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDDEIAQVQL
                     STTTGSIYLKDTDK"
     gene            16449..16757
                     /locus_tag="ACIZE5_000720"
     CDS             16449..16757
                     /locus_tag="ACIZE5_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0080135 - regulation of cellular response
                     to stress [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGC6107885.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTKKRKEAEKIDDDEWSDF
                     "
     gene            16757..17107
                     /locus_tag="ACIZE5_000721"
     CDS             16757..17107
                     /locus_tag="ACIZE5_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HGC6107886.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALFVAILM
                     SLVNVIVSEHNSRK"
     gene            17273..18211
                     /gene="hprK"
                     /locus_tag="ACIZE5_000722"
     CDS             17273..18211
                     /gene="hprK"
                     /locus_tag="ACIZE5_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HGC6107887.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            18226..19056
                     /gene="lgt"
                     /locus_tag="ACIZE5_000723"
     CDS             18226..19056
                     /gene="lgt"
                     /locus_tag="ACIZE5_000723"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HGC6107888.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLVLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGSLPDYDRSLGKNQQII
                     "
     gene            19100..20125
                     /locus_tag="ACIZE5_000724"
     CDS             19100..20125
                     /locus_tag="ACIZE5_000724"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HGC6107889.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHHLPDSIRAFTDMEDAVKDADAVLFVIPTKAIRSVAKELVAKLNTKPVI
                     IHASKGLEQGTHKRISEILLEEIPTEKRKAVAVLSGPSHAEEVAKHDITTITAASTNV
                     KAAKYVQELFMNHYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            20140..21078
                     /gene="galU"
                     /locus_tag="ACIZE5_000725"
     CDS             20140..21078
                     /gene="galU"
                     /locus_tag="ACIZE5_000725"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGC6107890.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYIMSLGKTLEAEGSKINHNPKGITEIKEEKKK"
     gene            21203..21652
                     /locus_tag="ACIZE5_000726"
     CDS             21203..21652
                     /locus_tag="ACIZE5_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HGC6107891.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTQDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIVTKVGGIGKTTAKATVAGKVGGTAMKFLKTKNILKRQEENKNG"
     gene            21645..22259
                     /locus_tag="ACIZE5_000727"
     CDS             21645..22259
                     /locus_tag="ACIZE5_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGC6107892.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSSELTGIAKEKAQDLSQQAGDLAGNVKQKVSESAEEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDLKKPADELGSIAKDTSEDIMIDVKDAADKAGETVNEG
                     MSEAKPVADDTKEMLKMAKEDAKEDAKEAKKEMKDTMTDSTTNH"
     gene            complement(22322..23425)
                     /locus_tag="ACIZE5_000728"
     CDS             complement(22322..23425)
                     /locus_tag="ACIZE5_000728"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HGC6107893.1"
                     /translation="MNNVKINELRQWMAQHQLELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVDRFDAISDILTGTDSYTDLTSIIQRLQLIKTVEEKDKLIEAGKWADVAF
                     EIGFKTVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGSTKVSP
                     NELVLFDLGVIWNGYCSDATRTVAYQKPTEFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLE"
     gene            23635..24636
                     /gene="ccpA"
                     /locus_tag="ACIZE5_000729"
     CDS             23635..24636
                     /gene="ccpA"
                     /locus_tag="ACIZE5_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HGC6107894.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            24990..25385
                     /locus_tag="ACIZE5_000730"
     CDS             24990..25385
                     /locus_tag="ACIZE5_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107895.1"
                     /translation="MPKKRRKTIVIILTILTIGIGGKFYMDKREAQKQQDLLAVEKQS
                     VKVLKNTFADIKEVKIEQFEKNDMTGIYEALITMTNTEGKAVYFDYSFTKESNEIDGY
                     GVENEEVQKEGITVDEIIVIYTDGSEEKV"
     gene            25382..26638
                     /locus_tag="ACIZE5_000731"
     CDS             25382..26638
                     /locus_tag="ACIZE5_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HGC6107896.1"
                     /translation="MTITDKQYKGISNKVYWLDPKHPQYSKSYKEGAIKNFGETKFQI
                     LKIKNSFDGMQAMAVAPIKNGKVDISQVVIAFAGTNLSDWKDLETDARSVMNLYGNRP
                     GASFSEKATTNKILSVSGLKTAGQINSAIAFANEVKKEYGEAAISTTGHSLGGFLALY
                     VAAEKQWKNVGFNGPDPYDLLSPEAKKWVEENPGMLTNYRNHADFIGNFGGNGTGAEV
                     RISMETAYLNLLASHSLTSWKFDENGKLIIPENENNVKARKQQKENQATQLFSYQLQE
                     LNNIRKKLRLSGGRLTVNEQIYLDDTQARLVVEKLSVKMKSAMEEVIRINQRGIFELE
                     KKWQEGLRQARVVAPSLTEQEIIEALASVGATKENLVDSAKEVYLLRINKARRMGEAF
                     DTLAKEIQDKINEIVARDRELAQQFN"
     gene            26650..26973
                     /locus_tag="ACIZE5_000732"
     CDS             26650..26973
                     /locus_tag="ACIZE5_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107897.1"
                     /translation="MKLEELERDYRSERRQLEAQEDELIHFKNQGLRLMEQEEQRLHH
                     VLKNLALDNEPLFQARRSYSNYQEHYQQALQVERRKLYQQQDELERSYRQKIRQITME
                     KSSYE"
     gene            26966..27232
                     /locus_tag="ACIZE5_000733"
     CDS             26966..27232
                     /locus_tag="ACIZE5_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107898.1"
                     /translation="MNEFLMQLLKELEKNLHRSNVRSVGMGISQQTWAEKRLTDQNHQ
                     MTAEEATQEFSNRHAHLKESVKGQFAEKLTELFQRQEKKLKQFR"
     gene            complement(27395..29740)
                     /locus_tag="ACIZE5_000734"
     CDS             complement(27395..29740)
                     /locus_tag="ACIZE5_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HGC6107899.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLLFAA
                     LGIGIGAGYFAYLVEDTQLPTKKELQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIVLSAQVEKHFSKDEIITTYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSEAYYQKAQQTIQNKGYTIHSTIDKDIYAALQTGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLVGSES
                     RVSDYATTWQEGKNAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINEKITTPFKDVISSLNGNLGNA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSQARIRSANYLANLINQAY
                     QANPEIFGTDEKFDLSSDVMKKKVSGFTGQTAGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANPETKESDDKDD"
     gene            30019..30921
                     /locus_tag="ACIZE5_000735"
     CDS             30019..30921
                     /locus_tag="ACIZE5_000735"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HGC6107900.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAFMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGAEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKVIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     ISMFKAQAFDPEVFPELLAEEVTL"
     gene            31132..32907
                     /locus_tag="ACIZE5_000736"
     CDS             31132..32907
                     /locus_tag="ACIZE5_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HGC6107901.1"
                     /translation="MLNILNPLIDQLKKKHTYFILGIAVLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIHYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     ILASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPTVEIIIA
                     CLLAIYYRKYNSSKKLLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYGIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFDFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVIGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIAVTSMLVFSKLNLKKALSSK"
     gene            complement(33216..34802)
                     /locus_tag="ACIZE5_000737"
     CDS             complement(33216..34802)
                     /locus_tag="ACIZE5_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HGC6107902.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            35053..35277
                     /locus_tag="ACIZE5_000738"
     CDS             35053..35277
                     /locus_tag="ACIZE5_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HGC6107903.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            35419..37170
                     /locus_tag="ACIZE5_000739"
     CDS             35419..37170
                     /locus_tag="ACIZE5_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HGC6107904.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQQLEAKIEGGEA"
     gene            37170..38954
                     /locus_tag="ACIZE5_000740"
     CDS             37170..38954
                     /locus_tag="ACIZE5_000740"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6107905.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGVYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFVAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            39289..40140
                     /gene="licT"
                     /locus_tag="ACIZE5_000741"
     CDS             39289..40140
                     /gene="licT"
                     /locus_tag="ACIZE5_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HGC6107906.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQNNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            40237..42123
                     /locus_tag="ACIZE5_000742"
     CDS             40237..42123
                     /locus_tag="ACIZE5_000742"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGC6107907.1"
                     /translation="MGKYQELARKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTAFLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLKAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYMDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(42164..43066)
                     /locus_tag="ACIZE5_000743"
     CDS             complement(42164..43066)
                     /locus_tag="ACIZE5_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGC6107908.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            43296..44699
                     /locus_tag="ACIZE5_000744"
     CDS             43296..44699
                     /locus_tag="ACIZE5_000744"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGC6107909.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMATMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     DLIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            44699..46132
                     /locus_tag="ACIZE5_000745"
     CDS             44699..46132
                     /locus_tag="ACIZE5_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGC6107910.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFPV
                     ITGKKKMFEFDKDHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     NEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDTVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            46277..47203
                     /gene="trxB"
                     /locus_tag="ACIZE5_000746"
     CDS             46277..47203
                     /gene="trxB"
                     /locus_tag="ACIZE5_000746"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HGC6107911.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            47417..49144
                     /locus_tag="ACIZE5_000747"
     CDS             47417..49144
                     /locus_tag="ACIZE5_000747"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HGC6107912.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLIDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDDEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAMRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     AIIKKMTEE"
     gene            49160..49510
                     /locus_tag="ACIZE5_000748"
     CDS             49160..49510
                     /locus_tag="ACIZE5_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HGC6107913.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(49604..50464)
                     /locus_tag="ACIZE5_000749"
     CDS             complement(49604..50464)
                     /locus_tag="ACIZE5_000749"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HGC6107914.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLMQALQDALKEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            50556..50984
                     /locus_tag="ACIZE5_000750"
     CDS             50556..50984
                     /locus_tag="ACIZE5_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HGC6107915.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            51146..51322
                     /gene="rpsU"
                     /locus_tag="ACIZE5_000751"
     CDS             51146..51322
                     /gene="rpsU"
                     /locus_tag="ACIZE5_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HGC6107916.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            51349..51795
                     /locus_tag="ACIZE5_000752"
     CDS             51349..51795
                     /locus_tag="ACIZE5_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HGC6107917.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(51951..53330)
                     /gene="brnQ"
                     /locus_tag="ACIZE5_000753"
     CDS             complement(51951..53330)
                     /gene="brnQ"
                     /locus_tag="ACIZE5_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGC6107918.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            54036..55007
                     /locus_tag="ACIZE5_000754"
     CDS             54036..55007
                     /locus_tag="ACIZE5_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HGC6107919.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            55031..57223
                     /locus_tag="ACIZE5_000755"
     CDS             55031..57223
                     /locus_tag="ACIZE5_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HGC6107920.1"
                     /translation="MLNKTLQKLQKKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSVV
                     LMKFFQLFQTEQAAYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTVILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIIYQGMSFGD
                     ATTWLTLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYVKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKSEVEKIKEEQEE"
     gene            57240..57716
                     /gene="ybeY"
                     /locus_tag="ACIZE5_000756"
     CDS             57240..57716
                     /gene="ybeY"
                     /locus_tag="ACIZE5_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HGC6107921.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLELPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISTER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            57700..58095
                     /locus_tag="ACIZE5_000757"
     CDS             57700..58095
                     /locus_tag="ACIZE5_000757"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGC6107922.1"
                     /translation="MDLKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFSVIVGLILFVPKIYHLLFN"
     gene            58110..59009
                     /gene="era"
                     /locus_tag="ACIZE5_000758"
     CDS             58110..59009
                     /gene="era"
                     /locus_tag="ACIZE5_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HGC6107923.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            59152..59964
                     /gene="recO"
                     /locus_tag="ACIZE5_000759"
     CDS             59152..59964
                     /gene="recO"
                     /locus_tag="ACIZE5_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HGC6107924.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRHIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICERHWSMDDHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRELIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTSEKDMSEKDLPKKEE"
     gene            60350..61267
                     /gene="glyQ"
                     /locus_tag="ACIZE5_000760"
     CDS             60350..61267
                     /gene="glyQ"
                     /locus_tag="ACIZE5_000760"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HGC6107925.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            61269..63344
                     /gene="glyS"
                     /locus_tag="ACIZE5_000761"
     CDS             61269..63344
                     /gene="glyS"
                     /locus_tag="ACIZE5_000761"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HGC6107926.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKESKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIDAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            63729..64508
                     /locus_tag="ACIZE5_000762"
     CDS             63729..64508
                     /locus_tag="ACIZE5_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107927.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHFNNQRQHHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSLIEQIRNEKIRAAYASKAETVAQQMGYSNTSY"
     gene            64549..65493
                     /locus_tag="ACIZE5_000763"
     CDS             64549..65493
                     /locus_tag="ACIZE5_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGC6107928.1"
                     /translation="MAKRRRRSRGKKIFLIILAILVVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGHDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYRDAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            65509..66288
                     /locus_tag="ACIZE5_000764"
     CDS             65509..66288
                     /locus_tag="ACIZE5_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="HGC6107929.1"
                     /translation="MEETISLKEIFETLRKHVITILISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQATSTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAPTQPKATNDKTAPSRRSRSRV"
     gene            66301..66999
                     /locus_tag="ACIZE5_000765"
     CDS             66301..66999
                     /locus_tag="ACIZE5_000765"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0004715 - non-membrane spanning protein
                     tyrosine kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HGC6107930.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENMSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            67027..67791
                     /locus_tag="ACIZE5_000766"
     CDS             67027..67791
                     /locus_tag="ACIZE5_000766"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsB/CapC family capsule biosynthesis tyrosine
                     phosphatase"
                     /protein_id="HGC6107931.1"
                     /translation="MIDLHCHILPGIDDGAENIDASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIDRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEQLFFELLQLGKTPVIVHPERNAHFRKDPNHMLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKMMVKHNLVQMAASDAHGVSKRTFYLKECYKQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEIKKKKFGLF"
     gene            67804..69621
                     /locus_tag="ACIZE5_000767"
     CDS             67804..69621
                     /locus_tag="ACIZE5_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HGC6107932.1"
                     /translation="MFVLTRRRKIATLVVVDSLLLIAANIAAAKFMKPFVAIPMDLIL
                     ISTGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFGSLSASDVSSILILLFINRQYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYVSADSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIQVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESAHVKVNTMPSIEELASGKISVSKLKTIDVVDLLGRDEVKLDIESI
                     KDQITDKVILVTGAGGSIGSEICRQIIQFNPAKLLLLGHGENSIYLIDRELRTHHQNC
                     PTEIVPIIADIQDREKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAKGGPITVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSIQKVMDFVKSLPQDDEQLAKDIVTFANASNK"
     gene            69635..70858
                     /locus_tag="ACIZE5_000768"
     CDS             69635..70858
                     /locus_tag="ACIZE5_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HGC6107933.1"
                     /translation="MNKLEKRQIPFSPPDITDLEIKNVVEVLKSGWITTGPKTKKLEK
                     KITKWLGTSKVVCLNSQTAAAETGLRLLGIGENDEVIVPAYTYSASASVVCHIGANLV
                     LIDCQQDSLEMDYDALEAAITEKTKVIIPVDLGGIPCDYDRIFEIVEKKRNLFQPSNE
                     IQKAYGRIIVMADSAHAFGANWHDQMVGNVADLTTFSFHAVKNFTTAEGGALVWKEHD
                     KLDNEAMYHQCQLLSLHGQSKDALTKTQLGAWEYDIVGPWYKCNMTDVTASIGLAQFE
                     RYPNILKRRKNIIKRYDEAFQQLGIEVLMHYTDDYSSSGHLYITRVPNISSEQRNEII
                     IKMAEQGIACNVHYKPLPMFTAYKNMGFDINNYPNAYAHFVNEITLPLHTKLTDEEVE
                     YVINNYSKIVKDLVG"
     gene            70872..71606
                     /locus_tag="ACIZE5_000769"
     CDS             70872..71606
                     /locus_tag="ACIZE5_000769"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003508523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGC6107934.1"
                     /translation="MRKWEDLPKEMQNDEIRYYYDILSKKKFSLVVKRVFDILVSATL
                     LLTLSWLFFILAIVIKIDSPGPVFYRQERITRYGKKFKIYKFRTMVINADKDGTLVTV
                     KNDDRITRVGKVIRKYRLDEISQLINVLVGDMSFVGTRPEVGKYVKSYSPLMLATLLL
                     PAGITSETSILYKDEDKLLHDKNNIDKTYIEKILPSKMYYNLKSISEFSCMNDLKIMC
                     KTIFVIFGKEYHADLEGEREFINQIK"
     gene            71626..72234
                     /locus_tag="ACIZE5_000770"
     CDS             71626..72234
                     /locus_tag="ACIZE5_000770"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF012792.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6107935.1"
                     /translation="MIEEIKSSDKELINSIVDIHMRTFTNFFLTFMGKKFLELMYRSY
                     TEYNDSGILVAIQNDKPIGFLAYSGDMSGLYKYMIKKRIIPFGFYSCVAFIKKPNILM
                     RLFRAFLKPSETKRDENYVELASIGVNPKEKSIGVGSMLIDNLKSRIDFSKYEYIALE
                     TDALNNDVVNNFYKKNEFILERKYSTNEGRIMNEYRFYMEKN"
     gene            72237..73382
                     /locus_tag="ACIZE5_000771"
     CDS             72237..73382
                     /locus_tag="ACIZE5_000771"
                     /inference="COORDINATES: protein motif:HMM:NF012744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGC6107936.1"
                     /translation="MKLLYILNVANKVNNFSKASMMAAKQTGLEFYIAGNWKYKSDEE
                     RKADEVKYGIKIYQVDFYRNPLNLKNIKAYHQIVEIIKNEKIDIIHCNTPIGGVVGRI
                     AGLKCKVKKVIYQAHGFHFYSGAPKINWFIYYPMERWLAHYTDVLITINHEDYTLAQK
                     LRLRKGGKAYYIPGVGIDTNRFMSSTSIRNFRESICKELNIPDTAKIILSVGELNENK
                     NHLSVIHALQKIPLHTDIYYIIAGVGEMRETLQNIANELGLHQRVFLLGYRSDIPKLL
                     AAANIYILPSLREGLNASLMEAMASGLPCIVGNIRGNVDLIEDGKGGFLINPKDEEEI
                     AGAINRLADNKLLCESMGAHNLDKIKDFDLSVVINQINNVYHEIVSK"
     gene            73405..74457
                     /locus_tag="ACIZE5_000772"
     CDS             73405..74457
                     /locus_tag="ACIZE5_000772"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGC6107937.1"
                     /translation="MKKIKIMHLLQSNRFSGAENIVCQIMSLFQNNEKFEMIYVSPDG
                     PIANILNIRGLSYLPLKKFSRKEIDRAVHELNPDIIHAHDFNASVRASRYKKQIILSH
                     LHNNPLWLPKLDIRTIIYSLCSSRFNSVIGVSNSVKEEFRYKQLIKDKFVLLPNTVNT
                     ERIIKMGNEFVEDDIDILYVGRMAEPKNPIGAINVLENVVKKYSKHLRVVMIGEGPLF
                     DEVKMQIQKRNLTDVIELKGFKSNPYKYMKKSKVLLMPSLWEGFGLVSVEAMLLETPV
                     VAYNVGGLKDIIDETNGFLCGSEVELSNSLMKLLNSEELRKKMGENAAISAKKFSNMN
                     RYQGVLEKIYVSAALK"
     gene            74986..75762
                     /locus_tag="ACIZE5_000773"
     CDS             74986..75762
                     /locus_tag="ACIZE5_000773"
                     /inference="COORDINATES: protein motif:HMM:NF016800.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HGC6107938.1"
                     /translation="MAFQVYLQRVYILSTGVIIGHYAEMGLNRIAYAGLMGDFSFAGL
                     YLATGCLYAFLKYVDLKNWKLLFFIIIEVFLLGAILCVSARTGLVSLFVTMTLYYLFN
                     INRISVPHLLVLIGGIITTPYILVMLMAGRSGQSLLDSSGRLENYMSSLNAFSDKYLI
                     GYGLGLNNLYTLLGVAVPHNFFIQYLLQTGIIGTLIILSGFFKFTYEELKKSGCYKWL
                     FLMIVVGAMFIPDIVSSRFLYAIVVLCMISASERTIKKES"
     gene            75773..76234
                     /locus_tag="ACIZE5_000774"
     CDS             75773..76234
                     /locus_tag="ACIZE5_000774"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HGC6107939.1"
                     /translation="MRRKAEKWADKACRQYRNGQNKMSKISCYILRIIYGCEFYGQVD
                     FSSNAQLVHNGLGCVFHPKTKIGNNCKIYQNVTLGGNGKIINGKETVGAPTLEENVAV
                     FAGACVLGPINIGHDSIIGANAVVTKSVPPYSLVYGNPAIITELKFDYKFD"
     gene            76293..77750
                     /locus_tag="ACIZE5_000775"
     CDS             76293..77750
                     /locus_tag="ACIZE5_000775"
                     /inference="COORDINATES: protein motif:HMM:NF024832.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HGC6107940.1"
                     /translation="MGNNIHGKTAKALKWSSLAEIIAKIITPISNMILARLLTPDAFG
                     VVATVTMVISFADMFSDSGFQKFLVQHEFDNEEHMFSSTNVAFTSNLGISLLLWLFIC
                     VFNNKIAHLVGNSGLGLVIIVAGVSLPITSFSSIQSAIFRRNFDYKILCYARIISALI
                     PLVITVPLAIIGLSYWSLVIGSIIGNLVTAAILTKLSEWKPKLFFSKKEFYEMFSFSA
                     WSLVESLGTWLSSYIGTFIVGGILSVYYLGIYKTTMTTVNGIFAIVTSATTTVLFSTL
                     SRLQNSKTEYDKTYLDFIKIVSIFIIPLGIGIYVYRELVTNILLGSQWKEAVPFVGIY
                     GLMSCFTLVLGQYASEYYRGLGKPKANVLMTILHLAVLIPVLIIYSRKGFIELAYGRS
                     FVKIEQIIVFWIILWFGFKFNPFKILKQVWKSCASALLMGVLAKIMLEFCTNYVMQLL
                     SVCLCVILYFFIYSCIFKGKTEIINMVRMFTGKGY"
     gene            77785..78954
                     /locus_tag="ACIZE5_000776"
     CDS             77785..78954
                     /locus_tag="ACIZE5_000776"
                     /inference="COORDINATES: protein motif:HMM:NF045194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGC6107941.1"
                     /translation="MKKVTILIPGMYYGGMERVAFITRQILLKNNYNVSFVTLFDNDA
                     DYQPNFEYLSLKCDIKPSKFGKVINIFKRVYKMKSVKKKLKTDITISFGQSCNLVNVL
                     SKRDDKVYVGIRSYDWLFQYIFHYYVDKFVYKKADAVVSVSQLIKRDAENIFNFNKDK
                     SYFLYNPYDLELINNKSKEKITEIEVPTDKKIIVTVGRLEDQKGLYHLIKAISMLKNK
                     DNVVVYILGHGTKKELLENLIKAYQLQNVIFLLGGQSNPYKYMSRADLYVMPSITEGF
                     PNALVEAMSTETAVLCADCKSGPREILSNRTLDTICENIEYAESGILVCPMTDSRNYS
                     PQYEECDKNLANAIEELIENDNLRNKYAKAAKKRAELYSYDAFEHNLLQIMKTFN"
     gene            78992..80083
                     /locus_tag="ACIZE5_000777"
     CDS             78992..80083
                     /locus_tag="ACIZE5_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HGC6107942.1"
                     /translation="MLKKNTSLQNKTILITGAAGFIGSNLVLELLRTQSSIKIIGIDN
                     MNDYYDVSIKNYRLSEIETEAKNHPGSTWNFIKGSIADKATIDFLFDNYKPSIVVNLA
                     AQAGVRYSITNPDMYIESNIIGFYNILEACRHSYDNGESGVEHLVYASSSSVYGTNKK
                     IPYSTEDKVDNQVSLYAATKKSNESMAHAYSKLYNIPSTGLRFFTVYGPAGRPDMAYF
                     GFTDKLRAGDNIQIFNYGNCKRDFTYIDDIVEGVKRVMQCAPEKIDGEDGLPIPPYHI
                     YNIGNNTPENLLDFVDILQQELIAAGVLPEDYDFESHTELVPMQPGDVPVTYADTSAL
                     ERDFEFKPSTSLRDGLRKFAQWYKSFYEV"
     gene            complement(80151..81629)
                     /locus_tag="ACIZE5_000778"
     CDS             complement(80151..81629)
                     /locus_tag="ACIZE5_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HGC6107943.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRVESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIATLLA
                     QHNQVTAVDILPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGAAAYREADFVV
                     IAAPTNYDSKQNYFDTSAVESVIKLVLEVNPKAIMVIKSTVPVGYTESIRKKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQTDKTLREASHTFADLLQEGAIKKDIETLFM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQEIIHGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDVPQNMISAIVDSNRTRKDFIADRVLELAGTYEANSSW
                     NAEKEKEVVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGATIVIYEPTLENNTTFFG
                     SKVINNLDDFKNISHSIIANRYDSNLDDVKEKVYTRDLFQRD"
     gene            complement(81895..82643)
                     /locus_tag="ACIZE5_000779"
                     /pseudo
     CDS             complement(81895..82643)
                     /locus_tag="ACIZE5_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
     gene            82786..83736
                     /gene="pfkB"
                     /locus_tag="ACIZE5_000780"
     CDS             82786..83736
                     /gene="pfkB"
                     /locus_tag="ACIZE5_000780"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HGC6107944.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQKKQIQTEFIEVPGMTRINVFTQVNQTREE
                     YKLVNQGPEIPQAAVHNFLNQIRALQAEDYLCVSGSLPRGMSPKVLVEISRICQEKEI
                     HLIIDSSDQEVMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVESGAENV
                     LLSLGEKGAILFTKDRVIRGNSPKGKVVNTACAGDAMLGTFLVGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIKEERFERWENIN"
     gene            83718..85181
                     /locus_tag="ACIZE5_000781"
     CDS             83718..85181
                     /locus_tag="ACIZE5_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HGC6107945.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGITIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFAGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTILADNEAVDTLESETISGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSFDPDHAQYNATAAMLKTVGDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     SGGTGFLVGILAGFLAGYFILFLQKLLTILPKQLDGLKAIFLYPVIGVVFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGPINKAAYVTGTALLAQGN
                     TTFMAGVSVACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKMDNKAANRTVIEEGRAGGLS"
     gene            85178..85636
                     /locus_tag="ACIZE5_000782"
     CDS             85178..85636
                     /locus_tag="ACIZE5_000782"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose PTS transporter subunit IIA"
                     /protein_id="HGC6107946.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIAHDEKEVYRK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSMIIVTLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRKAKSKTEIATILTKEIGEDL"
     gene            85633..86607
                     /gene="lacD"
                     /locus_tag="ACIZE5_000783"
     CDS             85633..86607
                     /gene="lacD"
                     /locus_tag="ACIZE5_000783"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HGC6107947.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPECGLPAAALREKECGLLLAYEKTGYDTKMPGR
                     LPDLLNIWSVKRLKEAGADACKFLLYYDVDEPAEINVQKQIVIERIGSECDAEGIPFF
                     LEILSYDATIGDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QETCYSQAEASAYFYEQSKVTEQPFIFLSAGVNATLFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLKETATPVYVDR"
     gene            complement(86786..87736)
                     /gene="yidC"
                     /locus_tag="ACIZE5_000784"
     CDS             complement(86786..87736)
                     /gene="yidC"
                     /locus_tag="ACIZE5_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0051205 - protein insertion into membrane
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGC6107948.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(88174..88449)
                     /locus_tag="ACIZE5_000785"
     CDS             complement(88174..88449)
                     /locus_tag="ACIZE5_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HGC6107949.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            88557..89321
                     /locus_tag="ACIZE5_000786"
     CDS             88557..89321
                     /locus_tag="ACIZE5_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HGC6107950.1"
                     /translation="MKEIQSAKNPKIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLAEVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            89444..89947
                     /locus_tag="ACIZE5_000787"
     CDS             89444..89947
                     /locus_tag="ACIZE5_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGC6107951.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            90355..91002
                     /locus_tag="ACIZE5_000788"
     CDS             90355..91002
                     /locus_tag="ACIZE5_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HGC6107952.1"
                     /translation="MEQTIKPYQYFFIKREVEQLLNAYSSVNDPKTVQTVQALATEKI
                     RDILEHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMIYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     regulatory      91044..91110
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            91165..92433
                     /locus_tag="ACIZE5_000789"
     CDS             91165..92433
                     /locus_tag="ACIZE5_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HGC6107953.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     gene            complement(92460..93659)
                     /locus_tag="ACIZE5_000790"
     CDS             complement(92460..93659)
                     /locus_tag="ACIZE5_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HGC6107954.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYAWQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(93778..95085)
                     /locus_tag="ACIZE5_000791"
     CDS             complement(93778..95085)
                     /locus_tag="ACIZE5_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HGC6107955.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            complement(95201..95323)
                     /locus_tag="ACIZE5_000792"
     CDS             complement(95201..95323)
                     /locus_tag="ACIZE5_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107956.1"
                     /translation="MHLIMIFSLLSIISLFAFSASRLLDAETQPIPVKVRKNDR"
     gene            95556..96674
                     /locus_tag="ACIZE5_000793"
     CDS             95556..96674
                     /locus_tag="ACIZE5_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107957.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            97058..97378
                     /locus_tag="ACIZE5_000794"
     CDS             97058..97378
                     /locus_tag="ACIZE5_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107958.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            97830..98030
                     /locus_tag="ACIZE5_000795"
     CDS             97830..98030
                     /locus_tag="ACIZE5_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HGC6107959.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            98177..100966
                     /locus_tag="ACIZE5_000796"
     CDS             98177..100966
                     /locus_tag="ACIZE5_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HGC6107960.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFIYVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGTGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMTTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            101013..101540
                     /locus_tag="ACIZE5_000797"
     CDS             101013..101540
                     /locus_tag="ACIZE5_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HGC6107961.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            101561..102751
                     /locus_tag="ACIZE5_000798"
     CDS             101561..102751
                     /locus_tag="ACIZE5_000798"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGC6107962.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFLKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            102791..104089
                     /gene="asnS"
                     /locus_tag="ACIZE5_000799"
     CDS             102791..104089
                     /gene="asnS"
                     /locus_tag="ACIZE5_000799"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HGC6107963.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVPEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
BASE COUNT        34405 a        18033 c        22020 g        30129 t
ORIGIN      
        1 gagtttcctc ctcttttaga tgaaatatga ataaattatg aagttcttac tttaatacgc
       61 ttaagatatt tcaattatct ataactaatg ataaaatgaa aagtaaagtc tacatagtct
      121 ggataataca cagaaggaaa aggagattac acaacgcatg gccaatttga ttcgttcact
      181 tatcgaaaac gataagaaag aactaaaacg tttagatagc attgcaaaaa aagttgaagc
      241 atacgctgac caaatggcag cattaactga tgaacaatta caggcaaaaa ctgctgaatt
      301 caagggcaga taccaaaaag gagaaacatt agatcaatta cttccggaag cttttgcagt
      361 cgtccgagaa gcagcaaaac gtgtattagg tttatatcca taccacgtac aattgatggg
      421 tggaatcgtg cttcacgatg gaaatatccc tgaaatgcgt actggtgaag gtaaaacctt
      481 gaccgcaacg atgccagtat atctaaatgc tctgactggc gaaggggtac acgtagttac
      541 cgtcaatgaa tatttagcaa cccgtgactc gacggaaatg ggcgaacttt ataatttctt
      601 aggattaaca gtggggttga atatcaactc aaaatcttcg gatgaaaaac gcgaggctta
      661 taattgtgat atcacttata gtacgaataa tgaattagga tttgactact tgagagacaa
      721 tatggtcgtt taccgccatc aaatggtaca acgtccgctg aattatgcca ttgtcgatga
      781 agttgactca atcttgattg atgaagcgag aacgccgctg atcatttcag ggcaagcaga
      841 aaaatccaca gctttatata caagagcaga caacttcgtg aaacgtttga aagaagaaga
      901 agattataaa atcgatgtac aatcaaaaac aatcagttta accgaagcag ggatcgaaaa
      961 agcagaagaa acattcggtt tggataactt atacgacatt gaaaatactg cattgaccca
     1021 tcacttggat caagcattga gagccaacta tatcatgctt ttagatatcg attatgttgt
     1081 ccaagacgga aaagtactga ttgttgacca gttcactggt cggatcatgg atggacgccg
     1141 ttattcagat ggacttcacc aagcaatcga agctaaagaa ggcgtagaga tcgaagacga
     1201 aacgaaaacc atggcgacga tcactttcca gaactatttc cgtatgtaca agaaacttgc
     1261 gggaatgact ggtacagcta aaacagaaga agaagaattc agagaaattt ataacatcca
     1321 agtataccag attccgacaa atcgtccggt tatccgtgat gatcgtccag atttgcttta
     1381 cccaacatta caaagcaagt tccacgctgt cgtgcaagat atcaaagatc gctaccgcaa
     1441 aggtcaacct gtgttagtcg gaactgttgc ggttgaaaca tctgagttat tatcagatat
     1501 gctgaatcaa gaacgtattc ctcatgaagt gctgaatgcg aaaaatcact ttaaagaagc
     1561 agagatcatc atgaatgctg gtcaaaaagg tgctgtgacg attgctacca acatggctgg
     1621 tcggggaaca gatatcaagt taggacttgg ggtaagagaa cttggtggtc tagcagttat
     1681 cgggacagaa cgacatgaat ctcgtcgtat cgataaccag cttcgaggac gtgcaggacg
     1741 tcaaggagac cctggtatgt cacagttcta cttgtcattg gaagatgatt tgatgaaacg
     1801 attcggttca gaacgaatca aagctttctt agatcggatg aagatcggtg aggaagatgc
     1861 tgttatccaa agcaagatgc tgacgaaaca agtagaatct gcacaaaaac gtgtagaagg
     1921 aaataactat gacacacgta aaaacgtctt acaatacgat gatgtgatgc gtgaacaacg
     1981 tgaagtaatc tataaacagc gacaagaagt aatcatggaa gaaaaaagct tatccaagcc
     2041 actaatgaac atggtcaaac ggacaatcag tcgtgtagta gatgcgcata cacaattaga
     2101 gaaagaaaat tggaatttgg aaagtatcat cgattttgcc ggcagtactc ttgtccatga
     2161 agatagcatt actcttgcag atatcgaagg aaaaacagct caggagatca aagagtatct
     2221 aaacgaacga gcacaagaag tatttaatac caaagcggct caactaaatg gtccagagca
     2281 actgttggaa tttgaaaaag tcgtgatctt gcgtgttgtg gactctaaat ggacagacca
     2341 tattgatgca atggatcaat tacgtcagtc aatcggctta cgtgcttatg gacagaacaa
     2401 tccattagtc gaatatcaaa cagaaggcta taagatgttt gaagatatgg taggcgccat
     2461 cgagtatgaa gtcactcgaa tctttatgaa agctgagatc cgtcaaaacg tacagcgtga
     2521 acaggtttct caaggaacag cttctcactc agaagacgga gatgccaaag aaaatagtaa
     2581 tactagcgcg aaaaaacagc caatccatgt gaataaggtc ggaagaaatg atccttgtcc
     2641 ttgtggaagc gggaaaaaat ataagaactg tcatggaaaa aatgcaaact aatttctgac
     2701 agcaggattg gtgagacaaa ttcttttttt aagaattcgt ctcaccttct ttctgttatt
     2761 tgctgattct gttagactag atataatgaa aaaagtatag tgaaagaagg aaaaaacatg
     2821 gaaatatccg aaattcgaaa tctcctgaca gaaatgcagg aaaaggtcac aagtttcagg
     2881 aggtctcttt gacttagatc agctggaaga agacatcgcg gaagcagaag caaaaatggc
     2941 tgaacctggt ttttgggatg acagcgaagc cgcacaaaaa gtgatcagcg aaaataacgc
     3001 taataaagaa acctatgacc aattccattc tcttgccgaa gaactagaag aaatcgaatt
     3061 gatggtggag atgctgcaag aagaacctga tgcagcaatg caagaagaag cagaaacacg
     3121 tatcaatgca ttagatgaaa aaatgaagac gtatgaatta tctatgctgt tagacggacc
     3181 ttatgatcga aacaatgcga tcgtcgaatt gcatccaggg gctggcggaa cggagtccca
     3241 agactggggc agcatgcttt tacgtatgta tacacgttgg gcagagcagc atggctatca
     3301 agtagaaaca ctagattatc aagcaggtga tgaagcaggg atcaagagtg tgaccctgct
     3361 gattaaagga cataacgctt ttggttatct aaaatcagaa aaaggtgttc atcgccttgt
     3421 acggatttcg ccttttgact cagcgaaacg acgtcatact tctttttgtt cggtagatgt
     3481 gatgccagag cttgatgaaa cgatcgatat agaaatcaat ccagatgatt tgaaaatcga
     3541 tacgtaccga gcaagtggtg caggtggtca gcacatcaat aaaacagaat ctgctgtacg
     3601 gatcactcac ttgcctacag gaacagtagt agctagtcag gcacaacgct cacaattgaa
     3661 aaaccgtgag caagcgatgg ggatgttaaa agctaagctt tatcaattag aagtggaaaa
     3721 gaaagaacaa gaagcagctg cacttcgagg agaacaaaaa gaaatcggct ggggttcaca
     3781 gatccgttct tatgttttcc atccctattc tatggtaaaa gaccatcgga caaacgtaga
     3841 gacaggaaat gtccaagctg ttatggacgg agatcttgat ttatttattg acggctattt
     3901 gaaaatgcat ctgcaataag agccctttgt taaattgaaa taaaattgta agattttgca
     3961 agcaagttga aacattgcca tgctataata gctaaagact gaaaaagata tggagagaac
     4021 gccatgattg aaatgaagga tgtaatgaag aagtactcaa acggtacgac cgctatccgc
     4081 aatctctcga ttgtcatcga acaaggagag tttgtgtatg ttgttggtcc gtctggagct
     4141 ggtaaatcta cattcatcaa attgatgtat cgagaagaaa aagcttcaaa aggaactttg
     4201 aacgtcgcag gtcatgatct aatagccatc aaaaaccgcg aagttcctta tctacgcaga
     4261 gaaatcggcg tggtgttcca agactataaa ttattaccaa gaaaaacagt atatgaaaat
     4321 gttgcgtacg ccatgcaagt tatcggcaga aaacctcggg atatcaaaaa acgagtaatg
     4381 gaagtgctgg atcttgttgg tttgaaacac aaagtccgag tctttcctag cgaattatct
     4441 ggtggggaac aacaacgtgt ttctattgcc cgagcaatcg taaatacacc taaagtactt
     4501 atcgcggatg aaccgacagg gaatctagat ccggaaaact catgggaaat catgaaacta
     4561 ttagatcgga tcaatgcaca aggaacaact gtcgtgatgg ctacacataa cagtacgatc
     4621 gtaaatacga ttcgacaccg agtaattgct atcgaaaacg gccgcattat tcgagaccaa
     4681 gcggaagggg aatatggata cgatgattag aacctttttc cgccatttat tagaaagtat
     4741 caagagtttg aaacgtaacg gctggatgac agtagcttcg gtcagtgcgg taacgatcac
     4801 gttgacttta gttggtgtgt tcatggcggt catcatgaac gcaaccaaac tagcacaaga
     4861 tatagaagga aacgtggatg tatctgtgtt cgtagacatt ggtacaaaag acgaagagat
     4921 gaaaaaatta gaaaaagaat taaatgactt agatcatgtc aaaaaagtcg aattttcaag
     4981 caaagaacag gaattgaaga aaatccaaaa cgaaatgggc gattcttgga aattgtttga
     5041 aggggataat aacccgttat atgatgtata cgtagtaagt gctaccgatc cttcttatac
     5101 aaaacaagta gcagaaaaag cggcagattt gaagaatgtt tcccgttctg attacggtgg
     5161 ggcttcctca gatcggattt tccaaattgc tggtgcagtt cgaacatggg gattagttgc
     5221 ggcggcattg ctgctgtttg tagcaatgtt tctcatttct aacacgattc ggatcacgat
     5281 tttatctaga cagcgtgaaa ttcaaatcat gcgtttagta ggggcaaaaa atggatatat
     5341 ccgctggcca tttttccttg aaggtggttg gatcggctta atcggtgcca ttcttccgat
     5401 actgatcatt acatttggtt acgcatggtt ttaccaattg atcaatccgt cattattacg
     5461 atctcattat tcattgatcc atccagaaaa tatcgtttgg aaaatcaatc ttttgatggt
     5521 cggtattggt gtgatcattg gttcactcgg ctcgatcatc tctatgagac gtttcttgaa
     5581 attctagtgt cacaagataa atataatcag aaagttggac gatttcgttc cagctttctt
     5641 tttttatcag ctaggtggag taaatggggc ggcttttttc tctttacttt aaaaaacaac
     5701 ttgggtattc ttaagttggt agaaaaagag gtgaagccgt gaagattatc gttgacaatt
     5761 tttttacgat ccttttgatt atgaatattt tgctttcctt tattatcgtt tttcgagaaa
     5821 gaaaggaaac tgcgcaaaca tgggcatggc tgctcgtttt gatgttcatt ccagttgtag
     5881 gatttatttt atatattttt ttaggaagag ggatttccaa agagaaaatc tttgatttga
     5941 agatccaagg gaaaatcggt aagaatctag aaatcgaaga agataaacaa gcattgatgc
     6001 gagggcttta tcctcatccg cctactggac aagtagatgt gaaacaattg atctatatgc
     6061 ttactgtatt tgaaagtacg ctttatacga ctaaaaatga aatcacttta tttacagatg
     6121 gtcgtgaaaa attcgatgcg ctgatcgagg atatcaaaca ggcagaagac catatccatt
     6181 tccaatatta tatttaccgc agtgatacat taggtgaaga agttcgagag gcattgacag
     6241 aggcagcaag acgcggagta aaagtcagag tccttcttga tgcatggggt tccacacaag
     6301 tttcttctag tttttttcag aatttgaaaa aagcaggtgg agaagtcgca tttttctttc
     6361 ctctattcgt tccgtatatc aatcctcgaa tcaattatcg caatcatcgt aaaatcgtag
     6421 tgattgatgg gaaaatcgga tatacaggtg ggttcaatgt tggaaacgaa tatctaggat
     6481 tggtaaagaa atttggttat tggcgagaca atcatctgcg tatctatgga gaagcggttt
     6541 acaccttgca aaaccgtttt ttgatggact ggaattctca gcatacaaaa gaagtaggat
     6601 attcaccgga atttttcccg accattcatt ctacaggtga tatggctgtt caaatcgtga
     6661 caagcggacc agataccgaa catgagcaaa tcaaaatgac atatttgaaa atgatttcgt
     6721 tagccaaacg ggagatattg atccaaacgc cgtattacat accggatgga tcgattcatg
     6781 aggcattgaa gttggctctt ctctcaggcg taaaagtcca tatccaaata cctaacaaac
     6841 cagatcatct tctcgtttac tgggcaacgt attctttcgc tgcagagctg atcgagtatg
     6901 gggcaagaat cgaaacatat gaaaatggat ttatccatgc aaagacgatg attatcgatg
     6961 gcggcatcgt ttccgttggt tcagctaata tcgacgttcg ctcatttaga ttggattttg
     7021 aagtcaatac actgatctat gatgaacgaa tggcttctcg cgtaagaaaa gcattctttg
     7081 aagattcaaa gatttcgacg catctcacaa aagaagtgta tgaaaaccga gggatgatga
     7141 tcaagatgaa agaaggatta gcaagactga tttcgccgct cctttaaaat acaaaaagga
     7201 caggagagcc atcaatagat ggaaatctcg cgtccttttt tctcggggcc atttctgaga
     7261 gtacgtcaga aatggagaaa gcgtctcgca tgagcgaaat taactttggg gtatctcttg
     7321 ttttttgggg aaagcaagaa ataagctaat atatgctatt aaaagagaca catttcaaag
     7381 ccagtatagc atagaaactt ttaatgagat agcttttttt gcaattatga gaatttattt
     7441 tgttatttaa tgattttgat tcgttttcat caagtaatga aaatgataga ataaacatac
     7501 tttaggatta aaggagattt ctaatgaaaa aactaaaatt attcttacca ataataggat
     7561 tagctattct tttatcaggc tgttcaaagt ggattgatcg aggagaatcc attactgcag
     7621 ttggctcttc tgccttacag cctttagtag aaacggttgc tgaaacctac caggcagaaa
     7681 atcctggaaa attcatcaat gtacaagggg gcggaagcgg aactgggttg tctcaagtac
     7741 agtcaggagc agtcgatatc ggaaattctg atttgttcgc ggaagaaaaa tcagggattg
     7801 atgcttcggc attagtcgat catcgagtag cagttgttgg aatcactcct attgtgaaca
     7861 aggatattgg cgtaaaagat atcagtatgg aaaacctgaa aaaattattt acgggcgaga
     7921 tcaaaaactg gagtgaagtc ggtgggaaag atcagccagt agttatattg aaccgtgcat
     7981 caggaagcgg gacccgtagt acgtttgaaa aatgggtatt ggacggagaa acagctgttc
     8041 aggcacaaga acaagattca agcggaatgg tgcgccaaat cgttgcggac acacccggag
     8101 caatcagcta tgttgctttt tcttacgttt ccgatgatgt ggatacgttg aacgttaacg
     8161 gtgtggaacc aacagatgaa aatgtgacaa cgaacaaatg gacgatttgg gcatatgagc
     8221 atatgtacac aagagaccat ccaaaaaaac tgacaaaaga atttttagac tatatcttat
     8281 ctgatgaagt acaagataat attgtcggag agctaggcta tatccctgtt tcacatatga
     8341 aagttgaacg tgattggcaa ggaaacattg ttaaagagta atctttacac aaaatttaca
     8401 aacttagcta aacttttaca tgttattaaa accaaattga tgttcaattt gtacactgag
     8461 tgagtatgtt aaacctgatt aagggggagt catctgtgga agatgtgaaa aaagtattat
     8521 taacaaaatc aaaacgttca aaaatggaac agcgcggaaa attcattagt tttttgtgta
     8581 tcgcgctgat cgtgttggtt gtattatcta ttttttattt tgtcgctagt aaaggattgg
     8641 ccaccttttt tactgataag atcaatgtat ttgattttct gtttggtaca gattggaatc
     8701 caagccaaat aggagcaaat gggaaaccca tggtaggggc attgcctatg atcacaggtt
     8761 catttattgt gaccttttta tctgctattg ttgccacacc atttgctatt ggagcagcag
     8821 tgttcatgac ggagatttct cctaaaaacg gaacgaagat cttgcaaccg gtcatcgagc
     8881 tacttgtagg tattccgtct gtcgtttacg gatttatcgg tttatctgtt atcgtgcctt
     8941 ttgtcagaag tatctttggc gggacagggt tcggtatctt agctggtaca tttgtgttat
     9001 tcgttatgat cttaccgact gtcacaacga tgactgtgga tgcattaaag gcagtgccgc
     9061 gacactatcg ggaagcttca ttagcgctag gtgccacaag atggcaaaca atctacaaag
     9121 tggtgctgcg agcagcagtg cccggaattt taacagcagt cgtttttggt atggctcgtg
     9181 cgtttggcga agccttagct atccaaatgg ttattggtaa tgcggcatta atgccaacag
     9241 gacttactac tcctgcttct acattgacgt ccatcttgac aatgggaatc ggaaatacaa
     9301 tcatgggaac agttgaaaat aatgtgttat ggtcattagc gctgatcttg ctattgatgt
     9361 cattattctt taatatcgtg atccgtatga ttgggaagaa aggagagctg aaataatgaa
     9421 cgcaaaacgc tcagataaaa ttgctacagg tgttctatat gtggtttcag ggatcatcgt
     9481 attgatctta gcagctttat tactttatat cttagttcga ggaataccgc acatttcatg
     9541 gtcattcttg actgaacctt ccaaagccta ccaagaaggc ggtgggatcg ggattcaatt
     9601 atttaactcg atttatttgc ttttgattac catgatcatc agttttccta tctctttagg
     9661 tgcgggtatc tacctttcgg aatatgccgg aaaaaactgg ctgacagacg tgatccgtac
     9721 gtctatcgaa atcttgagct ctttgccttc tgttgttgtc ggtttattcg gtttcttggt
     9781 tttcgttatt caattccagt atggtttctc aatcatttct ggtgcattag ctttgaccgt
     9841 attcaacttg cctcttttga ctcgaacggt cgaggaatct ttacaagcgg tccattacac
     9901 acaacgagaa gctggattgg cgttaggttt gtcacgctgg gaaacagtga taaaagtggt
     9961 tgttccagaa gcgacaccag gaattttgac tggtgtgatc ctaagttcag gaagaatttt
    10021 tggtgaagct gccgcattga tttatacagc tggtcaaagc gcgccagcat tagattttac
    10081 gaactggaat ccattaagtg tttctagtcc gatcagcatt ttccgccaag ctgaaacact
    10141 ggctgtccat atttggaaaa tcaacacaga aggtacgatg cctgatggtg tttctgtttc
    10201 ggctggcgct tctgccgtgt tgatcattgc tgttttactg ttcaacttcg gcgctcgtgc
    10261 gattggcaaa cgattatacc gaaaaatgac ttcagcctaa ggagaagaag taaaatgaaa
    10321 aaatataatt ggaatgaaac aaatgtcatt accatgccaa aagataagga agttgcatta
    10381 tatacgaatg atctgcatgt ttggtatggc gacaatgaag caatcaaggg agtggatcta
    10441 gaattcgaaa aaaataagat cactgcattg attggtccct ctggctgcgg aaaatccacg
    10501 tatcttcgtt ctttgaatcg tatgaatgat gggattgcta atacgaaaat tactggaaag
    10561 attatgtata aagacgtgga tatcaatgcg cctcaagtgg atgtttatga aatgcgtaaa
    10621 cggatcggca tggtgttcca acgccccaac ccttttagca aatcgattta tgacaatata
    10681 acttttgctt tgaaacagca tggtgaaaaa aacaaaaaga aattagatga aatcgttgaa
    10741 acaagcttga aacaagcagc tttgtgggat caagtaaaag atagcttgga taaaagtgcc
    10801 ttggctttat ctggcggaca acagcaacgt ttgtgtatcg ctcgtgcaat cgcgatgaaa
    10861 cccgatatct tgctgttaga cgagccggca agtgccttgg atcctatttc gacaggaacg
    10921 gttgaagaaa cacttgtaaa cttgaaagaa gactacacga tcattatcgt gacgcataat
    10981 atgcaacaag cagctcgtat cagcgactat actgcctttt tctatctagg aaaagtaatg
    11041 gaatatgaca aaacaaacaa gatatttacc agaccaaaaa ttcaggcaac cgaagattat
    11101 gtgtccggtc attttggtta agacggaggc ctcaacatga caaaagaaat tatctcatcc
    11161 aaagatcttc atctgtatta tggaaagaaa gaagcactaa agggaattga tctaagtttc
    11221 aatcaaggtg aaatcacagc gatgatcggt ccttctggtt gcgggaaatc tacctatcta
    11281 cgttcgttga atcgaatgaa cgatctgatt ccaaatgtaa cgatcaccgg aagtgtttta
    11341 tataaagaca aagacatcta tggtccgaaa acagatgttg ttgaactaag aaaagaaatc
    11401 ggcatggtgt tccaacagcc aaatccattt cctttttcta tttatgaaaa tgtcatctat
    11461 ggattgaagt taaaaggtga aaaagataaa aaagtccttg atcaagtagt ggaagaaagt
    11521 ctgaaggcag cgtccgtttg ggaggatgtg aaagataaac tgcataaaag tgccttgtct
    11581 ttatccggtg ggcagcagca gcgtgtatgt atcgcacgtg ttttggcagt gaatcccgaa
    11641 atcatcttat tggacgaacc aacaagtgca cttgaccctg tttctactgg gaaaatcgaa
    11701 agtatgctgt tagaattaag agagcggtat acgatgatca tcgtgaccca taatatgtct
    11761 caagcttcac gtatttcaga taagacggca ttctttttag atggtcactt gatcgaatac
    11821 aacgatacga agaagatatt catgaatcca gaaaaacaag agacagaaga ttatatttca
    11881 ggtcgatttg gataaggagg aaacggaatg ctacgtacac aatttgaaga agaattgctg
    11941 aatctccata atcagttcta cgaaatgggg atgatggtga gcagcgctgt gcacaagtca
    12001 gttcgtgcat acatcaaaca cgataaaatc ttagctcaag aagttatcga aaacgatata
    12061 aatatcaata atatggaaac gcgtttggag aagaaaagtt ttgaaatgat tgcattacaa
    12121 cagccagtta caactgactt gcgtatgatt atcacggtca tgaaagctag ctctgattta
    12181 gaacgtatgg ccgatcatgc ggtgtccgtt gctaaatcca caatccgcgt aaaaggacag
    12241 acgagaatac cggaaatcga aaaagagatc tccgatatgt ccgattacgt gaaaaaaatg
    12301 gtggacaacg tcctagttgc gtatgtcaaa acagacgaaa aagatgcgcg tacaatcgcc
    12361 aatatggatc aaagagtcaa tgactatttc aatcgaatct ataatgcaac catcaaaaac
    12421 atgcaagaaa atcctgaaac agtcatcagt ggcacagact atttgaatgt tgccagctat
    12481 ctagaacgaa tcggagacta tgtgacaaac atctgtgaat ggatcgtcta cttggctaca
    12541 gggaaaatca ctgaattaaa tacgaaccac aatgagattt tctaaactga agttgtgatt
    12601 ctgctgttta tttaggaaaa gaggttgtga aatcagcgtt ttgtcctgag tattagagaa
    12661 acaaacggta aaatagttcc tcatattttg ccgttttttg agctaatacc gaaggtcagc
    12721 tgattgaaca ccgtttattc tggaaaaggg tttgtgacaa aacatgtcac aaaccctttt
    12781 cattattcca atagaaagga taaagaatgc aaaaaaagat tagcatcatc atcactctat
    12841 tttttatttg tatacttgct tcatggttta ttcagcgtca agctgctcta tatgacgtac
    12901 ctgtcatcga gatcgaaaga gtgagaatag aagaggatca acaattgatt acaggaagat
    12961 tgatgaatac ggaccaaaaa ggagaagtga tttctttaac ggctccttat caaaaaaatc
    13021 aaatcgaaac agcaaatata acaacaagac aaatctatct tgtccaaatg catggagatg
    13081 aatggcaact agtagcaaaa aaaaatgatg gctggctttt tttctttaca agtgtcttca
    13141 ttggcaccat gttgcttatt ggtggaaaac agggcgtatt tgctttagga agtctcatca
    13201 tcaacatcgt tttactttta cttttgttgc tcctctttac caaaacagaa ggtatttctc
    13261 tcttaaatat agcaatctta tttgtcgtta tagggataat cgttagtata ttggcgttag
    13321 acggatggaa tagaagcagt ataatcaaaa tttcggctgc agttacaagt gtttttttag
    13381 cattttttat ttgtcttttg acaatgaatc attggaaaga tcaaggactg cgctatgaag
    13441 aactgaatta tctgacacga ccgtatcgtt ctgtttttct ttccagcgtg ctgattggga
    13501 cagctggagg gacactcgat accgtgatca cagtcattgc gacattagaa gaattgacca
    13561 agcaacaacc gaaaatatca gcgaaacagt tatggctttc aggaaggcaa gtgggccgag
    13621 atgtgattgg ttcgatggct aatatccttt tattcgtcta tatcagcgga gcgattccat
    13681 cgcttctgtt atatttagga aatcaatggt ctttcaaaga aacggtagaa cgacatttat
    13741 cattagaact tttacgcgtc attgctggca gcttaggaat agtattatca atccccatcg
    13801 cggtcctctt ttttctcgct gtaaggaggt taaaaaaatg aatgtactta ttatacttgt
    13861 tgggattttt gcaatcagtg tgctatttgt cggtggtacg caaggtatgt atattctttt
    13921 aggattattc attaatttag gaatcttttt cctattatta ttcggctatc atcagaagtg
    13981 gccgatattg gtattgtcga ttatagggtt cctattgatc gctgtggtta tcttattttt
    14041 tatcaatggt tataatctga aaatgcgagc cgcttttgcc agtatactga tctttttgtt
    14101 ttgtttccta ctattgattc ctatcactga ttttttagcg atccaaggct ttacttcgat
    14161 agaactagaa gaactatctg gcttagataa gacgttagca attgatttta gactacttac
    14221 gaggtcgttg cttctgatca gtcttagcgg agctgtttta gatgcgagtg tagcgatttc
    14281 tagtggaaca ttcgaagtat atcaggcaaa tccgcaaatg tcttttaacc aattgcgcca
    14341 tgctagcttt gccattgcta aaaaaatatt ggcatcaaca gtgatgacgc ttctttttgc
    14401 gtttatgggg agttctttag cgttgattct ttggtttatt gacttagaca tttcttttca
    14461 gcaaataatc aatgaaaaat catttgtctt ggaatatacg atggctattc ttaccacact
    14521 ggccgcacta cttgtcctgc ccttaacttg cgtgactaca gcatatctct ttacaaaaaa
    14581 gaaagaacat ctcaagatgg agtaaaagtt acaacttaag tcctatgaca tttttactga
    14641 atcagtgcat aatatggatg taaggaaaag cttgcaaaca attttgctta aggaggcaat
    14701 ttccatgaaa gaaagagaac gtattttaga cttagtgaaa aaaggaatcc tttcgactga
    14761 agaaggctta gatttattag aaagcatggc aactgaaaaa gacgaaaaac aaatcaaaaa
    14821 agaagcagac aaggtaactg ctagtcataa agaaaaagat caggcaagtc aattgatcga
    14881 tgaacttgaa aacggtgaag aaaaaatttc tgagccagtt gatccaaaag aaaaagaaag
    14941 acaagatcaa gaaaacttag aaaagatctt agatgaacta gcaactgaag cgaataaaac
    15001 ttcggcgcgt ctagacgaag taaatgctca attcgctgac aataaggcag cacgtaatga
    15061 gaaacaggaa gcattgatgc agctgaatac aaaagaagaa ttaggcgagt tgacagaaga
    15121 agaattagca cagcgtcaaa cgttagaagc agaaatcaaa gagttagaag caaccggcga
    15181 tacactatta gaagaacaat tgaagctgga agcagaatta aaagatatcc gcaagaatca
    15241 atggtctgag aaaaaagaaa catttacgga taagtttgaa ttgccagatg attggaaaga
    15301 tcaagcgaca gatacgctga atcaagtagg cgaaaaaatg tcagaagctg gatcacagtt
    15361 aggcaaattc ttgaagaaaa cattccaaac tgtttcagaa acagtaaatg ataacatgga
    15421 atggaaagat gtcagcttac gcgtccctgg aattgcgaca acgaaatttg aacacgaatt
    15481 ttattatgaa gctcctgcag caagtatcct tgatatcaag gcagcaaacg gaaacgtgac
    15541 gttaaaaacg tgggacagtg atgatgtgaa agtggaagcc aagatcaaac tttacggaaa
    15601 aatgggtgct gaaccatttg aagcattctc tgaacggagc cagatcgagg tcaatgaaga
    15661 tcatatctcc ttccaaattc caaataagcg tgtgcgtgca gaccttgttt tctacttgcc
    15721 taaacgagta tacgaccatg cagctatcaa acttctaaat ggcaacatca tgattgagac
    15781 attggaagct aaagatattt atacaaaatc tacgaatggg aacatcatcg tgaaccaatt
    15841 aactgcaacg atgctggaag tagaaggtgt aaacggcaat atcgatattc gaaacgggaa
    15901 catcttagat tctattatag aaacagtaaa cggtacagtg acatttggtg ccacaccaga
    15961 aaacctttct gtgtctttag taaatggtga tgtacgtctt acgattaaag aagataattt
    16021 gaaaaaagta gaagcaagtt cagtgaacgg gaatgtcaaa gttgctttac cagatagcat
    16081 cggtttggaa ggacacgcta aaacaagtct tggaagcatt aacagccgtc tgtccaatta
    16141 cgaagtagtt cgtgagaaaa aagaacggac aaaccaaatg ttgcaattcc gtcgtgtttc
    16201 agatgatgag atcgcacaag tgcagctttc aacgacaaca ggaagtatct atttaaaaga
    16261 tacagataaa taaagaggtt gtgaaagaga tgttcagcct tgagcaataa gaagcgattt
    16321 tttaaaatag cttcccctat tttaaaaaaa tgtgccttat tgccgatagg ctatctcttg
    16381 aacaccgatt aagaagaagg ttgtcacaac gattttcttc atttaaaata gtagaacaga
    16441 ggtgagacat gatgaaaaaa aagttgacaa aatccaataa aaatgttgtt ttgacaggta
    16501 ctttagcagg gattggggaa tatatcggga ttgatcccac tgttatccgt gtgctttatg
    16561 tattcttaag cttagttgct tttggaagtc caatcatttt atacatttta ttagctttga
    16621 ttatcccatc tgcgcgttct gcacgaacaa actatggaca taacaatgca tattatgaaa
    16681 aaaacaatta tcgtgaacaa acaaaaaaac gcaaagaagc ggaaaaaatc gatgatgacg
    16741 aatggagtga cttttaatgt cgtactttca gcgtattttg gttaatacgt taacattcat
    16801 atcgttggct gttctttttc ctgcgatggt ccatgtgagc agtatttgga cggccgtcct
    16861 tgccagcttc gtattatctg tgttgaacat gtttgtcaaa ccgattttga cgatcctgtc
    16921 cctgcccttt acattagtca cattgggatt gtttacgttt gttatcaatg cagcgattct
    16981 taaaatgact tccttttttg taggagcaga acattttagt ttttcttcat ttggtgcagc
    17041 gttattcgta gctatcttga tgtcacttgt caatgtaatt gttagtgaac ataacagcag
    17101 aaaataaaaa aagctgtgcc gagatctcgg cgcagctttt ttgtttagaa taaagaatgc
    17161 gttttctatt acattggtaa ttaaataaaa acgttttttt taattggtag tacttttggc
    17221 tagacaatga taaaatgata gagaacactc taatagaaat gaggtagcat gaatgtcaga
    17281 agttgtaaaa gttagccaat tagtaaaaaa attatctttg gaaatcgtca caggcgacga
    17341 gaaaagttta gaccgcgtca tcgtgactgg ggacatctca cgcccaggac tagagttgac
    17401 cggttatttt aattattatt cccataatcg tttacagcta tttggcagta aagaaatcag
    17461 ttttgcggaa cggatgatcc cagaagagcg tttgatcatt atgagaagat tatgtagtga
    17521 agatatgccc gcatttatta tttcaagagg attgccggct ccggaagaaa tgatccaagc
    17581 agccaatgaa aatgggatag ctgtgctgcg ttcgcctatc tcaacgtccc ggctgctagg
    17641 tgaattatct agttatttag atggacgctt agcccctcga acaagtgtcc acggtgtgtt
    17701 agtcgatgtc tacggattag gtgtactaat tcaaggggac agtgggatag ggaaaagtga
    17761 aacggcgttg gaactgatta agcgcggaca tcgattgatc gcagacgatc gagtagatgt
    17821 ctatcagcaa gatgaactga cggtaatcgg agaacctcct aaaatcctgg aacatctgat
    17881 tgagattcga gggatcggta tcatagatgt aatgaatctt ttcggtgcga gtgcggtacg
    17941 aggctctatg caagtccagt tagctgttta tctagaagca tgggcgaaag ataagaaata
    18001 cgaccgtctg ggctctgaag acacgaccgt tgaaatcgcg gaagtgggca ttccacaaat
    18061 aaaaatccct gtcaaaacag gacgaaacgt tgcaatcatc attgaagtag ccgcaatgaa
    18121 tttccgcgca cgtacaatgg gctttgacgc aacgaaaaca tttgaagaaa gattaagtcg
    18181 cttgattgaa gaaaactcag gcaatgacta gcaaggagtg acaatatgtt agcacaaatc
    18241 aatcgagttg cttttgagct tgtaggaatt cctatctact ggtatgcatt gattatcgta
    18301 tcaggaatca ttattgccat gtggctcagc agcagagaag ctgttcgggt aggattaaaa
    18361 gcagatgacg tgacagattt tatgttgtgg ggattgccga tttccattat tggtgcccgc
    18421 ttgtattatg ttttattcga tcttccccaa tatatagctg atccaatcca gatattcaat
    18481 atccgttcag gaggattagc gatttacggg ggattgattg caggtgcaat cacactgtac
    18541 ttttttacca aatatcattt tatttctttg tggacctttt tagatatcgc tgcaccaagc
    18601 gtattattgg cgcaggcaat cggacgatgg ggaaatttca tgaaccacga agcgtatggt
    18661 ccagacacga cacgaagttt cttagaaagt ctgcatttac cgcaattcat cattgataac
    18721 atgtatatcg aaggaatcta tcgacaacca acctttcttt atgaatcact ttggagtttg
    18781 attggattta ttctgctttt ggttttgcgg aagaaaccac atcttttgaa aaaaggagaa
    18841 gtccttttat gttatctaat gtggtatagt ttcggacgtt tctttatcga agggttacgc
    18901 acagacagcc tttacttttt aggtgtgatc cgcatttctc aattattgtc tgctgtttta
    18961 tttgtcggca cattgattct gtttatttgg cgtagaaaaa aaggaagttt accggattat
    19021 gaccgctcat taggaaaaaa tcaacaaatt atttgatttt cagagcgtta aaaatgaaaa
    19081 aaatttcagg agtggtaaaa tgaattatag agtagcggtt ttaggaccag gctcttgggg
    19141 gactgcttta gcacaagtcc tcgctgaaaa cggacatgac gttcggattt ggggacatcg
    19201 tgcttcacaa gtagaagaaa tcaacaccca acacaccaat caacgttatt taccagatca
    19261 tcatctaccc gattccatcc gagcattcac cgatatggaa gatgcagtaa aagatgcaga
    19321 tgcggtacta ttcgttatcc cgacgaaagc gatacgttct gttgcaaaag aactagttgc
    19381 caaattgaat acgaagccag tgatcatcca cgcaagtaag ggattagaac agggaacgca
    19441 taaaagaatc tctgaaatct tgttagagga aatcccgaca gaaaaaagaa aagctgttgc
    19501 tgttctttct gggccaagcc atgcggaaga agtagcaaag catgacatta cgacgatcac
    19561 agcggcaagc acaaatgtaa aagcagcaaa atatgtacaa gagctgttca tgaaccatta
    19621 ttttcgaatc tataccaacc ctgatgtgat tggtgtagag atgggagcag ctttgaaaaa
    19681 tattattgcc attggagctg gtgctattca cggcttaggg tttggcgata atgcaaaagc
    19741 ggcaatcatg acgcgcggat tagctgagat cagccgttta ggtgtagcaa tgggtgccaa
    19801 cccgctgacc tttattggct taagcggagt aggtgatcta gtcgttactt gcacaagtgt
    19861 tcattccaga aactggcgcg caggcaactt gttaggacaa ggtcagcctc tagaagaggt
    19921 gctagccaat atgggaatgg ttgttgaagg tgtgaatact actcaagcag cgatggaact
    19981 agcccaaatg atggaaatcg aaatgcccat cactcaaaca atctatgaag tgctgtatga
    20041 acaaaaagaa atcaaaacag ccgcaaaaga aatcatgtta cgtgatggga aaaaagaaaa
    20101 tgaattctca ttaacaattt tttgaaggag cgaatgtata tgaaagtaaa aaaagcagtt
    20161 attccagcag caggattagg aacaagattt ttaccagcaa caaaggcgat ggcaaaggaa
    20221 atgttgccaa tcgtggacaa accaacgatc caattcatcg ttgaagaagc gttgaaatca
    20281 ggaatcgaag acatcttgat cgttacagga aaagctaaac gaccaatcga agatcacttt
    20341 gattcaaata tcgaattaga aacaaaccta agtgaaaaag gaaaaaccga attattgaaa
    20401 ttagtagaag aaacgacaga tgtcaatttg catttcatcc gtcaatctca tccaaagggg
    20461 ttaggacacg ccgttcttca agcaagagcc tttattggaa atgaaccgtt tgtcgttatg
    20521 ctaggcgatg atatcatgga agacgaagta ccattgacac agcaattgat cgatgactat
    20581 gagcgtacac acgcttctac gattgccgtt atgcaagttc ctcacgatga aacttcaaaa
    20641 tacggaatca tcaacccagg ggaagtactg gaagatgggt tatacaatgt caaaaacttt
    20701 gttgaaaaac cagatccaag caaagcacca agtgatttag ctattattgg gcgttactta
    20761 ttgactccag aaatctttga tgtattatca gaacaacaac caggcgctgg aaatgagatc
    20821 caactaactg acgcaatcga tacgttgaat aaaacacaac gcgtatttgc ccgtaaattc
    20881 acaggtaaac gttatgacgt tggtgacaaa tttggtttta tgaaaacaag tattgaatat
    20941 ggtctgacac atccagaagt aggggcacct ttgcgtgaat acatcatgtc tttaggtaaa
    21001 acattagaag cagaaggaag caagatcaat cataatccaa aaggaataac agaaatcaaa
    21061 gaagaaaaga aaaaataatc tttttttcta acgagcttca gctgctaatt gaataaaaag
    21121 tagttgaagc tcgtttttat ttgtttaaaa aacacgaaaa tgctatcctt atagaaaaga
    21181 gagacaagaa gggagtttga tcatgtcagg aggagaaatt gcaggattga tcgcagcaat
    21241 cgcctttgcg atacttgtcg ttttcatcgt tcgcgtattg ttgcaagttt ccaaaacttt
    21301 agaaaaagta gaccagactg tcgcagaagc aaatacgaca attgagatcg tcacacaaga
    21361 cgtagatctt ttatctagac aagtagaagg cttgctagtc aaaagtaatg agctgctctt
    21421 ggatatcaat ggaaaagtcg caacgatcga tccattgttc acagcagttg ctgatttaag
    21481 tgaaagtgta tcggaactta atcattctag taaaaacatc gtgacgaaag tcggcggaat
    21541 cggaaaaacg acagctaaag cgactgttgc cggaaaagtc ggtggaacag cgatgaaatt
    21601 tttaaaaaca aaaaacatac tgaaacgaca ggaggaaaat aagaatggct aaaaaaggtg
    21661 gatttttatt aggtgcagta gttggaggta cagccgcagc aatcgccgca ttattgttag
    21721 cacccaaatc tggtaaagaa cttcgggatg aattggctgc tcaagcagat gatttgatgg
    21781 acatggcttc agattacaca gatatggcaa aagaaaaatc atctgagtta acaggtattg
    21841 caaaagaaaa agcgcaagat ctttctcaac aagcagggga tctagcaggc aatgttaagc
    21901 agaaggtaag tgaatcagca gaggaagcag gaagcgaatc agatgatatc ttgttaaacc
    21961 tcaaagaaca atcagctgat ttatctaatc gtttcaaaaa aacagcagaa gatctgaaaa
    22021 agccagcaga cgaattaggt agtattgcta aagatacttc agaagatatc atgatcgatg
    22081 taaaagatgc tgcagataaa gcaggagaga cggtcaatga aggaatgtca gaagcaaaac
    22141 cagttgcaga tgacacaaaa gaaatgttga aaatggcaaa agaagatgca aaagaagatg
    22201 caaaagaagc taaaaaagaa atgaaagata caatgacaga ttcgactacc aatcactaag
    22261 attactcatt tctagaataa aaaaggtgag agcggaccag ctctcacctt ttttattttc
    22321 attactctaa aacaagtaat tcttttggtg tagtcgtgaa tggcacacaa ccatcacttg
    22381 tcacatacac acaatcttcg atacgtaccc ctactttttc aggaatatag attcctggtt
    22441 caagagagaa gcacatccct tcttcaatca ctaagtcgtt tccttctaca agagaaggga
    22501 attcgtggac ggttgttccg attccgtgac ctaaacggtg attgaaatat tcgccgtagc
    22561 catagctgtt gatcacgttt cgtgcgattt gatcaagttc acctgctgtc acacctgggc
    22621 gaactgcctc ttgtgcggca agctgtgctt caagagtgat gttatagatt ttttcttgga
    22681 attcagttgg tttttgataa gcaactgtac gagtagcatc actgcaatag ccattccaaa
    22741 taacgccaag atcgaataac actagttcat ttggtgaaac cttcgtgctt cctggtgtac
    22801 catgagggct tgcagcattt gctcctgcaa ggactaatgt gtcgaaagac atttgtgaaa
    22861 caccttgttt ttttaattgg tattcgattt ctgcgataat tgcttgttca gttacgcctt
    22921 cttttactgt tttgaagcca atttcaaagg caacatcggc ccatttacca gcttcgatca
    22981 gtttgtcttt ttcttctacc gttttgatca gttgcagacg ctggataata gaagttagat
    23041 cggtgtaaga atctgtacct gtcaagatat cagagatagc atcgaagcga tcgacagtca
    23101 gagcattctt ttcaatacct acattaccag gttgcccata gcgtgcgcga agctcttttc
    23161 cgatgatctc ccaaggattt tcgctgtcta agtagccacg tacatcgtac gcccagctgc
    23221 tgttttgagc atcttcaact tccagagcag gagtgaaaag gaaaggatct tgttccagag
    23281 ggataaaaag agctagtaca cgctcgtgag gatcactttc atatccggaa aagtaagcga
    23341 tgtggccagg gtcgctgata taagccaatt ctaattggtg ttgtgccatc cattgacgta
    23401 gttcattgat ttttacgtta ttcatttggc aacctacttt ctaaattaat tttgtattca
    23461 ataattgtac cactgattga ttaaaagacc aacgttctta aaactgaaaa aagtaaaaat
    23521 tttcatgaaa acagagataa aacggttgca attgttgaga ttatttgata tcctatttta
    23581 gaaatgtaag acgtattttc agaaaacata taaaatatga ataggagaac acaaatggaa
    23641 aagcaaacaa tcactatcta tgatgtagcg agagaggcaa atgtttcgat ggctactgtt
    23701 tcacgtgtcg taaatggcaa tccaaacgtc aaaccagcaa caagaaaaaa agtcttggaa
    23761 gttatcgatc gcttggatta tcgtccaaat gcagtcgcac gtggcttggc aagtaagaaa
    23821 acaacaacag ttggggtaat cattcctgat gtcagcaata tgttctttgc ctctttagca
    23881 cgtggtatcg acgatgtggc aacaatgtac aaatacaata tcatcttagc aaactcagat
    23941 ggcaacgatc aaaaagaagt caatgtattg aataatttat tggctaagca agtggacggc
    24001 gtgatcttta tgggtcacca tatcacagac gaaatccgtg gagaattttc acgttcaaaa
    24061 acgcctgttg tactagctgg ttccattgat ccagatgaac aagtaggtag cgtaaacatt
    24121 gattatgtat cagcaacaaa agatgcagta aataaattag caaaaagcgg caataaaaaa
    24181 atcgcttttg tcagcggtgc gctgattgat cctatcaatg gtcaaaaccg tctaaaaggc
    24241 tataaagaag cattaagcga aaacaatcta ccatatagcg aaggattgat ttttgaggca
    24301 caatacaact ttaaagatgg tctgtctcta gttgaccgga tccataatag cggtgcaaca
    24361 gctgtctatg tttcagacga tgaattagcc attggtatct tggatggttt attagaccgc
    24421 ggcgtaaaag taccagaaga attcgaaatc atcacaagca acaattcttt actgacagaa
    24481 gtagctcgtc ctcgtttgac aagtatcaca caaccattat acgatttagg agcggtatcc
    24541 atgcgcctat tgacgaaaat gatgaataaa gaagaagtcg aagaaaaaac gattatcttg
    24601 ccttatggaa tcgaagaaaa aggatcaact aaataataaa agatcaatca tttaaaggtt
    24661 gttcccaaag tggtcaactt ctggaacaac ctttatacga gaaaaggggt tatgacaaaa
    24721 ttttgtcata accccttttt ttgtgacttt aaaaaaaaga gagaatggcg gaaacaaacc
    24781 ttacgtccat cgtatacgac acaatctgtg cgtagatgct acattttgtt cactactatc
    24841 aaaattactt taaaatgaaa acgtgataaa aaagaaagta gaaaagtaga aaagtaactc
    24901 taaaaaatcc aaaaaaatcc aggctcgatt gcgtacttat cttaaaggag aaacaatcca
    24961 tcatacataa cccgaaagga gacttctatt tgcctaagaa aagacgaaag accatagtca
    25021 tcattttgac cattcttact ataggaatcg gaggaaaatt ttacatggac aaaagagaag
    25081 cgcaaaaaca gcaagattta ctcgcagtag aaaaacagtc cgtcaaagtt ctgaaaaata
    25141 cctttgcgga tatcaaagaa gtgaaaatcg aacaatttga gaaaaacgac atgacaggaa
    25201 tctatgaagc attgataacg atgaccaata cagaaggaaa agccgtttat tttgattata
    25261 gctttacaaa agaaagcaat gagatagatg gctatggtgt tgaaaatgaa gaagtacaaa
    25321 aagaagggat tacggttgat gagattatag ttatctatac agatgggagt gaggaaaaag
    25381 tatgacaatt actgataagc agtataaagg aataagtaat aaagtatatt ggctagatcc
    25441 aaaacatcct caatatagta aaagttacaa agaaggcgcc attaaaaact ttggagaaac
    25501 aaaattccaa atcctaaaaa tcaaaaactc cttcgacggc atgcaggcga tggctgtagc
    25561 gccaatcaag aacggtaaag tggatatttc tcaagtagtg attgcttttg caggaacgaa
    25621 cttaagcgat tggaaagatt tggaaacgga tgcaagaagt gttatgaatc tctatgggaa
    25681 tagaccagga gcaagttttt ctgaaaaagc aacaacaaac aagattttat ccgttagtgg
    25741 attgaaaaca gcggggcaaa tcaattcagc gattgcattt gctaatgaag taaaaaagga
    25801 atatggagaa gctgctattt ctactaccgg ccattcatta ggtggattct tagcattata
    25861 tgtagcagca gagaaacaat ggaaaaatgt cggcttcaac gggccggacc cgtatgatct
    25921 cttatcacca gaagcaaaaa aatgggtgga agaaaatccc ggtatgctca ccaattaccg
    25981 aaatcacgcc gattttatcg gtaattttgg tggtaatggc acaggtgctg aagttcggat
    26041 cagtatggaa acagcatact tgaatctgct tgcttcccac agtttaacct cttggaagtt
    26101 tgatgaaaat ggaaagctga ttattcctga aaatgaaaac aatgttaaag ctcgaaaaca
    26161 acagaaagaa aaccaagcga cccagttgtt ttcctatcag ttgcaagaac tgaacaacat
    26221 acgtaaaaaa ctacgattaa gtggcggccg gctgacagtt aatgaacaaa tttacttaga
    26281 tgacacacaa gctaggttag tggtggaaaa gttatcggta aaaatgaaaa gcgctatgga
    26341 agaagttatc cgcatcaacc aaagaggaat ttttgagcta gagaaaaaat ggcaagaagg
    26401 cttgcggcaa gcacgtgttg tcgccccttc gttgactgaa caggaaatca tagaagcatt
    26461 agctagtgtg ggcgccacaa aagagaactt agtcgattct gcgaaagaag tctatctgct
    26521 acgaatcaat aaggcaagac gtatggggga ggcctttgat acattggcga aggagatcca
    26581 agacaaaatc aatgaaatcg tggcacgaga tcgagaatta gcacagcaat tcaattaaag
    26641 gagaagtaga tgaaactaga agaattggaa agagattatc gaagtgaacg aagacaatta
    26701 gaagctcaag aagatgaatt gatccacttt aagaatcaag gattacgatt gatggagcaa
    26761 gaggagcagc gactgcatca tgtattaaag aacttagctt tagataatga gcctctgttt
    26821 caagcaagac gaagttattc gaattatcag gagcattatc aacaagccct acaagtagaa
    26881 cgacgaaaac tctatcagca gcaagacgaa ctagaacgtt cctatcgtca aaaaatcaga
    26941 caaataacta tggagaaatc atcttatgaa tgaattttta atgcaattac taaaagaatt
    27001 agagaaaaat ctacatcgat caaatgtacg ttcagttggt atggggatat ctcagcaaac
    27061 ttgggcagaa aaacgattga cagatcaaaa ccaccaaatg actgcagaag aagctactca
    27121 agaattttct aaccgacatg cacacttaaa agaatcagta aaagggcaat ttgcagaaaa
    27181 actaaccgaa ttattccaaa gacaagaaaa gaaattaaaa cagtttcgtt agtaaagtta
    27241 tatagaaaaa ttttgtgaaa atggtttttc acatttttac ataaatttgt cttaatatcg
    27301 tagatgtaag cttttgaaca ccatttattc ggaaaaaggg agctgtgaca agatttttgt
    27361 cgcagctccc tttaattctg attaatctat tagatcaatc atctttatcg tctgattctt
    27421 tggtctctgg attcgctcta gcataagctg aagcggtgtt ccagtaatct gtatagtttt
    27481 catcagtacc gccaacgccg aatttaaagg cgcttttctt cggaccattt tttgcccaaa
    27541 gtgattccac tgtttttcct ggcgtttgga tagatttttt attgacagta acttttccag
    27601 ctgtttgtcc tgtgaaccca gatacttttt tcttcatcac atcggatgat aagtcaaatt
    27661 tctcatcagt gccgaaaatc tcagggtttg cttggtaagc ttgattgatt agattggcaa
    27721 gataattagc cgaacgtatt cttgcttggc tgtccattcc agtattgtca tcgtgtcctg
    27781 cccaactact gatagtgata gatggagttg agacgatcag ccatgaatct cggtattcat
    27841 tggtagaacc agtttttccg acccaatctg catttcctag atttccgttt aagcttgaga
    27901 tgacatcttt gaatggtgta gtgatttttt cattgatcac actacgcatc atgtcattca
    27961 tgatcgatgc cgttgcttcg gaataaatac ggacagaatt actttcatgt ttataaatca
    28021 cattacctgc attatctgtg atggaatcaa tgatatagcc ttcttcgtag actccaccat
    28081 ttgctaaggc ctggaatcca tttgtctgtt gaagcgtcgt tacatctact gtccctaaag
    28141 gagccgattc aacgccccaa ttatcatttg ctgggtagtt catcttcgcc aagtagtgct
    28201 cgtaagcgta ttgtttcgat ccaccggaat tcaacacatc ttgatataag tgataagctg
    28261 ggatattgtt ggaccattcc agtgactcac ggacggtttg gaaggtgttc gacccttcat
    28321 tggtcgcatt gacgattttc tcaccagcat tttttccttc ttgccaagtc gttgcataat
    28381 ctgatacacg ggattctgat ccgacaagtc ccatatcgat tgcaggaccg taaacaagaa
    28441 ccggtttgat ggatgaacca gcttgacgtt ctgtatcaaa ggcgtggtta ttttgattct
    28501 ggctgtaatt ccgaccaccc acgaagccat agatacgtcc ggttctgtta tccatcaata
    28561 catttccagt ctccacttgg ctaccagcac catcatctaa catgtagcca taattttcta
    28621 cgccggtttg caatgcagca tagatatctt tatcaatcgt cgaatggatc gtatatcctt
    28681 tgttttggat cgtttgctgt gctttttgat aataagcttc actgaccgat gaatctgaca
    28741 tatcagcatt atctttttct gccaattgtt gtgcaataat ccttgttgct tcgttcatca
    28801 cggtataata caagaattct ctgtcagtct gttccgcgat ttgttgtggg agaaagtctt
    28861 ttgtaagatc ataggctttc gcttcttcgt attgttcttt cgtaatttgt ccttcacggt
    28921 acatactgaa taaaacaaaa tcttttctgg caagaccggc agaaagatct tcttttagcg
    28981 cgcctgtatt cgtgtatgga ctatacgtga tagggctttg aggcaaacca gcgatataag
    29041 cagcttgcgg cagagtcaca tcctttgcat ctacaccaaa gattcctcta gcagcttcct
    29101 ggactccagc aatattttgc cccttattat tccgaccaaa tggtgagaca ttcaaatacg
    29161 tagtaatgat ctcatctttt gaaaagtgtt tttctacttg tgcagaaaga acgatctcgt
    29221 ttgctttacg tttgaatgtt gtttcatcgg ttaggatctg ttgtttgact aattgctgtg
    29281 tcaaagtgga tcctccagac gagccgatgc cagtcgcttc tgaaactagt gctcgtaaaa
    29341 cagctttagg gacataacct tggtgtttat cgaagtattc atcttctgta ctgataatcg
    29401 cggttttcaa taaaggcgaa atcttatcag atgaaatagt cgtccgcatc agatctgtct
    29461 ggatttttga tatctctgta ttatctgcat aaacaatctt tgacgtttcc gtaatgtttc
    29521 ctagttctgt ctgcagttct tttttagtcg gcaattgtgt gtcttcgaca agataggcaa
    29581 agtagccagc acctattccg atacctagag ctgcgaacaa caaaagaaga acagtaataa
    29641 aaacagtcaa tgattgaaac actctaaaaa taatcttagg aacaaaccat ttttcttttt
    29701 ttcttctatt ctgttttttt cgagtatttt tgcgtggcaa aagggtcacc tcaactaatg
    29761 gttttatttc gctaattata gcaaataata ggacaaaaaa acagacaagg ctgtttttga
    29821 caggaatttc tttttcgaat gagataaaac gtgaggaaat gatctttttt atgaaagagt
    29881 tcttaagctt ttctttaggg aaagtttcag ttactatgga gaacagggca aagaaaaaca
    29941 aactattttc tttgtacatc atcttatcaa tatacaggaa ttgttcgaaa caattgcctt
    30001 tcaaggagga atccatccat gttattaggc tcacacgtca gcatgagcgg aaagaaaatg
    30061 ctgttaggcg cggcagaaga agcagccagt tacggatctt cgacctttat gatctataca
    30121 ggcgctcctc aaaatactag aagaaaagct atcgaagaga tgaatattga tgccggaaaa
    30181 gcatttatgg cagaaaacgg actaacaaat atcgtcgttc atgcgcctta tatcattaat
    30241 ttgggaaata cgatcaaacc agaaatgttt ccatttgctg tacaatttct gagagaagag
    30301 attgtccgtg cggaagcttt aggtgctact caaatcaccc ttcacccagg cgctcatgta
    30361 ggagcagggg cagaagctgg gattgctaga attattgagg ggttgaatga agttttgaca
    30421 aaagaacaga cggcacagat cgctttggag acgatggcag ggaaaggtac ggaaatcggt
    30481 cgaacatttg aggaattagc gcaaatcatc gatggagtaa aattgaatga aaaattatcc
    30541 gttacttttg atacatgtca tacgaatgat gccggatata atataaaaga agatttttca
    30601 ggtgtaatgg aagagtttga taaggtcatc ggattagatc ggcttaaagt actgcatatc
    30661 aatgattcta aaaatcctca aggttctcat aaagatcggc atgccaatat cggttttgga
    30721 acaattggat ttgacacatt gaacaaaatc gtccatgatc caatgtttga caacatttcg
    30781 aaaatattag aaaccccata tgtcggtaaa gataaaaaga aagcttacgc accatatgga
    30841 aaagaaattt ccatgttcaa agcgcaagca ttcgatcccg aagtgttccc tgagttatta
    30901 gcagaagaag tcacacttta agttttctac ctgacagcaa caaaaaagga ttgggcagtc
    30961 tgccttgtcc ttttttgttt aagaaacaaa ggagtgcttt ttgcattcgt tttcgccatg
    31021 ctccttttgc cccctctttt taaattcaga caaacagggt atactgatag aaaagtaaaa
    31081 aacgaaaagt ttcacaaaca agtagcaaaa cgtgattgaa aggacgaaaa gatgctgaac
    31141 attttaaacc ccttgatcga ccaactaaaa aagaaacata catactttat tcttggcata
    31201 gccgtattat ttacaattat tcggttgtat ttatatagta aagcaatcta tggaacagat
    31261 atgtcggcga cctatgatga tcagctgctg attcactatg ctcaaaatat tttggatggt
    31321 aaatggctag gggagtacac gactacgaca ctttcaaaag ggatttccta cagcttgttt
    31381 ttagtacttg cacataaact gcatctttct tatgcagttt tattcggcat gttcagtatt
    31441 cttgccagta tattggttgc actagcgttt aaaccaatcg tgaagaacaa gtatcttctt
    31501 ttaagtatct atttttattt tttgttttct ccgattagtt ttacacatga atattccact
    31561 cgaacatatc gtaatgctct cgtgatcccg actgttgaga tcattatcgc ttgtttacta
    31621 gctatttatt accgcaaata taattccagc aaaaaattgc tgccgtggtt tttagggcta
    31681 gctgtttctt ttcctttctt ttggttcatt cgcgaagatt ccatctggct tcttcctttt
    31741 actgtagtcg cgttaggcat cagtttcgtt cagatcttgc taggacaaga cttttctttc
    31801 aaagaagcaa agaagttaaa agaacgacca tttctccttt cgaaacaaga atggctgaaa
    31861 ctttcattgt ttttactccc tctagtcggt ttctccatcg tctatcagtg gatcgaatat
    31921 aaaaacgaga caacatatgg tattgcagcc atcaatgacc gttcgagtgg cgaatttgga
    31981 cgtttgatga aacagctgat ccgaatagat gacgaaacaa acttaaataa agaaaacagt
    32041 gagatatggg tctcgcatgc tgcattaaat aaagctttag acgcatctcc tacatttcat
    32101 actgtttcta ctcgtattga cgaattgtat acgactcatg cgtggaccca aggcggaaaa
    32161 gtaaaagaat taccaggaga tatcattttt tgggcattgc gagatgtggt aagcgaatct
    32221 ggttattacc aaaacaatgc aaaagaaacc aatgattttt ggaaaaaagt caatcaagaa
    32281 ttagaagaag cctatcaaaa gggaactatc aaaaagaaaa aagaattcta tctgatggga
    32341 tcaggggatg gaaagacgat gaatgatctg ccaatcgtat ttgattttct gaaatcagga
    32401 tatgcttatg catggcgata caaagatttc catcaagggg ggaattatag ttttgggacg
    32461 caagaacaag tcgaacaggc acaagaatta ttgaatcttc cactaatgga taattggatc
    32521 gatagcagtg atccgagaac acctgatttc cagttgacaa aaacagcaaa agtcgcgaat
    32581 gtcatgataa aaatttacca agttctggcc attcccgtgc tgattgcttc aatagcaggg
    32641 atattactta tgatactagg aaccgtattt gcaaaagctg atcgtgccta ttatagttcc
    32701 tctttgattg tagtcatcgg attaatactg acacaattgg tttttctttt cggtgtctcg
    32761 tggttttgtt cttatgcgcc agaaaaaaag gattattttt taagtgtcta cactggcgca
    32821 ggcgtgccat taacgcaatt catcgcagta acaagcatgc tagtttttag taaattgaat
    32881 ctgaaaaaag ctttatcttc caaataaaaa gggaactgtg acaaaagtct tgtcgcagtt
    32941 cctttttccg aataaacggt gctcaaaagc ttgcatctgc ggtaataagc tcaaccaaac
    33001 gtaaaatatg aggaactatt tttgtttggc tgttcttatt acttgatgca gggcagcttt
    33061 ttcacaacct ctgatacacg gtgttccaga agtaacttct tcggaaataa gccgaaattt
    33121 cacaaaaatt tgaaaagcaa ttttcttaaa ttccttctta tttcttgaag ctgcccactt
    33181 ctgtcacaac ctcctttgtg taaaagaatc agtttctatt cgatttcttc tatcgtttct
    33241 tgcaaacgct gttcatattt tttgtttcct ttatataaat caccaatcgt ccatgccaac
    33301 aggagaagga caagaacaat gattacatag gcgatttgat cagccaatgc tagttgagct
    33361 gaggtggctt gctcgccgaa gaaactttcg atttgacctg gtaatcctcg taagttcaag
    33421 taagtcagac taatcacaga gaaccagcca agaagtttta caacaaatga atttttgaat
    33481 cggctcccca tctccgcttg gctattggtc atcatcagta aaggaatcat cgagaatggc
    33541 aatgcaaaag ccagaaaaac ttgggattca ttcatcaagt tattcaaagc ggtatgttct
    33601 tcgatcgttc cttttgtact tgtaaacaaa acacaaatca atacaggaat cacagaaagc
    33661 aatcgtgtga ctagtcttct tagccaaatc gggatacgca tatggatgaa tccttccatg
    33721 atgacttgac cggtcaacgt accagtaata gtagagttct ggccagaagc aagaagtgct
    33781 acagcaaata aagtagacaa gataccagat tttgctacag caatcaagat accattgctc
    33841 atagctgatg gatcagataa agcttcatac agaccaaaaa aggaaggatc ttggacagaa
    33901 ccggttttga atacagcgac acccatgatc aatagcagtg cattgactaa aaaagccatt
    33961 gacaactgga tattagagtc ccaagtagaa aagcgtaccg cttgtgctac atcttcttcg
    34021 tcttggtgat cgatcttccg agtttgagaa actgctgaat gaagatataa gttatgcggc
    34081 atgactgttg caccaataat ccctaacgct ccagtcagcg gagtttcacc acctatgaca
    34141 ggtgagtctg agaatgtatg actgttaggg ataaagccag caaataaact gtgccaatca
    34201 gggttagaca agccaacttg atagacgaaa acgaataaaa tgacgaaaat caagcagaca
    34261 accaaagctt cgattttacg aaacccgact tttgtcagca ataaaaggac gaaaacatct
    34321 aacacagtga taaatacggc aattaccaat ggaatatcaa aaagtaagta gagggcgatt
    34381 gctgcaccaa tgacttctgc gatgtctgtt gccataatgg ctaattcagt caagatccat
    34441 aaaatgacac ccaatgtctt acttgtccgt gctcggattg cttgggccaa atccatttgg
    34501 gtcacgattc ctaattttgc tgccatatac tgtaaaagca tagcaattag actagacatc
    34561 aaaataactg acatcaataa atattggaaa ttttgtccac cagtgatcga agtggaccag
    34621 ttacctggat ccatataacc aactgctact aatgcacctg gtccagagta agcaagaagt
    34681 gttttaaaaa aactttttcc ctttggtaca tccactgttc catttacttc agctaaagat
    34741 aaaccatttg tatgttcaat aagtcgatgc ttatgaaatt gtttgttgga ttgattattc
    34801 aagaaaaaac cacctttcct atttatctac gattacattc tacacctcag aaagaaaaaa
    34861 ttaaagaaaa agattcggta tgcctaattt tttttcgtgg cgtgtcttgc tggttaatga
    34921 aagaaatttt gttcttctct aaaaaaacca ctattttttg catgaaacta aagaatacgc
    34981 ctttcttttt tcaataaact ttagtaaaat aaatcattga gagcaattcg gaaatagaaa
    35041 ggagagattt atatggtatc aacaggtatt gtcgtactta ttgctattat tgctttgcta
    35101 atcggcgcag taggtggctt tttcctagcg cgtaaatata tgaaagacta tttagaaaaa
    35161 aatcctcccg ttaatgagga catgttgcga tcaatgatga tgtcaatggg gcaaaaacca
    35221 tctgagaaga aaattcgcca gatgatgcag caaatgaaga accaagggaa aaaataggtt
    35281 ctgacccaaa gactttttgc gggctgattt tttcagtccg ttttttattt cgtaatttgt
    35341 tagactattc agactattca gcaaaaaaga caaggacaga caatcctatg ctcttgataa
    35401 agacaaagga ggagtaaaat gtcgattttt agaaaattag gttggttttt tcgtcaggaa
    35461 aagaaacatt atttaattgg gattttctcc ctattcgcag tggccttggt acagttagtt
    35521 cctccaaaag tgattgggat catcattgat gagatcgccg ataagaattt atcaataaag
    35581 atcatttctt ggtggatctt actattgatc cttgcagctt tcttacaata tctttttcgt
    35641 tatatctggc ggacgaatat ttggggaagt gcagctcggt tggagaaaga acttcggcag
    35701 cagctattca aacattttac agaaatggac aatctctttt accaaaaata tcggactgga
    35761 gatttgatgg ctcatgcaac gaatgatttg aatgcaatcc agaatgtagc aggagctgga
    35821 atcttgacct ttgcagattc agtgattacg ggcggaacaa cgatcattgc gatgattttg
    35881 tttattgatt ggcgcttaac actgattgcg ctgattcctc tgcctttgct agccgttact
    35941 tcacgagtgc tggggtcaaa actccacgat gcttttcgtg attcgcaaga agctttttct
    36001 agtatcaatg ataagacaca agaaagtatc actgggatca aagtcattaa aacatttgga
    36061 caagaaaaag aagatctcgc ggattttgaa gaaaagattg aagatgcaat tattaaaaac
    36121 aaacgagtca attttttaga ctccttattt gatccattca ttaccttgat tatcggtctg
    36181 tcttatgttg caacaattat tttaggtgga aagtatgtct tggaaggcac gatctcgatt
    36241 gggcagatgg tctcatttat tagttatatc ggtatgcttg tttggccgat gtttgcgatt
    36301 ggccgattgt tcaacgtatt ggaaagagga aatgcttctt atgatcgcgt taatgaactt
    36361 ttgcatgaaa agacgcatat cgtggaacaa ctgggtgcag tgcagacccc ggcaaaaggc
    36421 gagctgaatg tagctatttc ctcttttaac tatccgaaag aagaatcacc agcattagaa
    36481 caaatcaaat ttgcgatcca agaaggagaa acattaggta ttgttgggaa aactggtgcg
    36541 ggaaaaacga caatcatcaa attactgatg cgtgaatacg atgattatca agggaaaatc
    36601 caatttggcg gacgttcgat caaagaatat tcattgaatg ctttattagg atcaatcggt
    36661 tatgtgcctc aggatcactt cctgttttcg atgaccattc gagataatat ccgtttttct
    36721 aatccaaaac tttcagaaga agaagtagag catgcggctt ctttagcatt tatcaacaat
    36781 gaaatcaagg aattgccaaa aggttatgat accttagttg gagaacgtgg agtctcttta
    36841 tctggcggac agaaacaaag gatttcgatt gctcgagcat tgatcaaaaa tcctgaattg
    36901 ctgatcttag atgatgcact ttctgcagta gatgccaaaa cagaagaagc tatcttgcat
    36961 aatttaaaag aaataagaaa agagaaaaca accatcattg cagctcaccg tttaagcagc
    37021 gtgatgcatg caaaagaaat cattgttgtc gatcaaggga aaatcattga acgaggaacc
    37081 caccacgagc tgcttgcatt aggtggctgg tatgaacgaa tgtgggaaaa acagcaatta
    37141 gaagcgaaga tagaaggagg cgaggcctga tggatgaaaa ttatcaatcg gaatggacaa
    37201 aatcgattcc acttaaagaa cagaagaaga tcatcaaacg actgatgaag ttcgccaaac
    37261 cttttagaag aacgttcatc gttgctatct tatttgcgtt tgccctgtct gtgatcaatg
    37321 tcctattgcc aaggatcatc caaactttta tggatgatca tctggctaaa cagtcagcta
    37381 cgacacaagt tattttgttt tttgctggtg tgtacttgtt tggagtcata gtcaaaagta
    37441 tcatttggtt tttccaatgg tatttgtatt ccatggcttc attgaagacc tatcagtatg
    37501 ttcgggtaag attatttgaa aagctgcata cactaggtat gcgttatttt gaccagacac
    37561 cggcaggatc gaccgtttct cgagtgacga atgacacaga aacgctattt gaattttggt
    37621 atgtcttttt gatggtattg actgggatct ttgcagtcgt ttcttctttc gttgccatgt
    37681 ttcaaatcaa tggagaaatt gccttgtgga ctttggtgtt cttgccgatt ttaggaatcg
    37741 tcatctggta ttaccagaaa ttcagttctc gtatttaccg aaatatgcgg gaaaaattaa
    37801 gtcagctgaa cacgaaattg aatgaatcga tttccggcat gcgtattatc cagcagtttc
    37861 gccaagaagc tcgtttagct aaagaatttg aacaagtgaa caacgagtat ttagacacgc
    37921 gctatgcgat gatcaaaacg aattcgattc tgttaagtcc gatcatcaat tttctctatg
    37981 cattggcgat tgcgttggcg ttgactttgt ttgggatcga tgcgttgcat tctcccgtag
    38041 aagttggact gatctatgca tttacgacct atgtccaggg attttttaat ccaatgtctc
    38101 aaatgatgga ctttttgagc acctttacag atgggatggt tgccggtagt cgtattttga
    38161 aaatcatgga tacagaagaa tatgcaccgc aacaaaatcc tggagcagat caagcgatta
    38221 cttcaggtaa gatcgagttt cgcaatgtaa gcttttctta tgatggagag cacaatgtat
    38281 tgaacaatat ctcttttgtc gctaatccgg gtgagaccgt tgcattagtg gggcacaccg
    38341 gaagcggaaa aagctcgatc atcaacgtat tgatgcggtt ttacgaattt tatgaaggcc
    38401 aaatcttgat tgatgatcat gacattcgag aatatccaat ggaagagtta cgtaagaaaa
    38461 tgggattggt cttgcaagat gccttcttgt tttatggaga tattgcagga aatatccgga
    38521 tgatgaatcc agctatcaca gacgaacaga ttcgccatgc agctgagttt gttcaagcaa
    38581 acaagttcat cgatgaatta ccaaaaggat atcactcaaa agtgatcgaa cacggtgcca
    38641 gctattctag tggacaacga cagctgatca cttttgcgcg aacaatcgtg acagatccta
    38701 aaatactagt attggatgaa gcaacagcaa atatcgatac tgaaaccgaa ggattgatcc
    38761 aagaaggatt ggcaaaaatg cgacaaggac ggacaacgat tgcgattgcc catcggctgt
    38821 ccacgattcg ggatgcagaa ttgattttag ttttagacaa aggtcatata gtagagcgtg
    38881 ggaatcatga aacacttcta gcgcaaaatg gtttgtatgc agatatgtac aaactgcaaa
    38941 gcagtggtgt gtaaaaagag gttgtgacag tagcatagta gcattttgtc ctaagcgcta
    39001 gagtgaaaat aaaacagagc ttcccagatt cttcatctgt gagcgttagt ggcgtagtca
    39061 cccgatttaa aaaagacgac gacagctagt caaaagtgcc taatagccac taagaaagcg
    39121 ttgacaaaag cgtttgcttt cgataatata aagaaaacga tacaacttgg atagtgattg
    39181 cctgatgcaa gctaaacctg atgagtctcc catggttcca tggacggctt tttgggtttt
    39241 tctttttgtt ttgaatacag ccctatatat catggaaagg agcaaaacat gctgattgag
    39301 aaagtactga ataacaacgt cgtaataacc agggatgaaa gaaatcagga aatgatcgtg
    39361 atgggaaaag gtttggcatt caaaaagaaa gtgggtgacc cgatttttga ctcatgcatc
    39421 gacaaaaaat ttcagttgac aaatgacggg ctttcacaac agttccaaga attggcacaa
    39481 gcgattcctc ttgagtactt agaaatttct tgtgaaatca ttgaatatac aaaagaggct
    39541 ctacaagtcc agttgaatga ttctgtgtat attgcattga cggatcattt gtatacggct
    39601 atcgaacgtc acaaaatggg aatatttgta ccaaatgtat tgctgtatga tatcaaacaa
    39661 ctatttccta aagagtatgc catcgggaaa aaaacagtga agaaaatctc ggataaatac
    39721 cacatcaagt tatcagaaga tgaagccgga tttatcgcat tgcatttagt caatgcacaa
    39781 ggcattcaaa gccaacaaaa caatacctac ctgtttacta taacaataca ggatattcta
    39841 aatatcgtcc gctattacta taagattaca tttgatgaag attcagtcca tttttttcga
    39901 ttcgtcacac acttacgttt ttttctgaca cgcgtcctag atggagaaaa atcagaagtg
    39961 ggagaagttt ctgaggaatt gtttcaggtt attcaaaaaa aatataagga tacgtttggt
    40021 tgcgttgaga aaatagcaga ctttttagcc gagacgttca actaccagat gtccacggac
    40081 gaaaaaatgt atttaacgat ccatactgcg cgtttagtgc atgagaatcg ttgtaaataa
    40141 ataaaaaaag gaggataaat taacaagaac gtatgaaata agggtagtga cattcagttg
    40201 gctaaacctt ccactaatat attggaggga atagaaatgg gaaaatacca agaattagcg
    40261 agaaaaatcg tagaaaatgt cggtgggaag gaaaatatca atggtttgac acattgtatc
    40321 acaaggcttc gtttcaaatt aaaaaacgaa gaaaaagcaa atgatgagat cttgaaaaat
    40381 atggacggta ttgtaacggt aatgcgagcg ggagggcagt atcaagttgt catcgggaat
    40441 catgtgccag tcgtgtttga agaggttata aaagcaggaa accttacttt tgatgaggct
    40501 gtttcaacag aaaaaatgag accgtttgat atgcttattg atggaatatc gggctgtttc
    40561 caaccattcc ttgctatctt agctgctggc gggatgattc gtggactgac agcattcctt
    40621 gtcttcttag gcgcgtttga ccgcggttct ggcacatttg ttatgtttga taatatcggt
    40681 gattctgtat tccaatttat gcctgttatt atcggtttaa cagctgcccg taaatttaaa
    40741 gtaaatgaat tcgtagggat gttgcttggc gcagcattaa tgaatcctag cttgtcgctg
    40801 gaagctttga gtggtgcagc agaagcacca ctaacgacca tattttctgg cactattttt
    40861 gaagcaccta tttatcaaac agtattcggc attccctgga ttgcgcgtaa ctacgcttct
    40921 tctgtcattc ccattatctt tattgtgttg ttagctagcc aaattcagaa accaattaaa
    40981 aagttagtac ctgagatgat cgcgaatttc ttcgttccat tcttcaccgt tcttattaca
    41041 atgcctttag gttttttact cgttggacca gtattcacat tcgcaactga tattttaatg
    41101 gctggatttg aaacactttt agcactttcg ccagttattt atggagcaat cgtaggcttc
    41161 ttctggcaaa ttctggtgat gtttggtctc cattgggcaa tcgtaccaat gggattgatg
    41221 caattttctg tgaatggttg gcaaaatatt atgacacctg ttgcagtagt gtcttttgga
    41281 caaactgcag cacttaccgc actctacttt aagcttagaa atccaaaaga caaagcaatt
    41341 gcaataccag ccattgtttc tggtattgtg gggattacag agccagctat ttatgggttt
    41401 acattaccac gtaaaaaaat atttattttt acttgtgtcg gtggtgcgtt agggggcgcg
    41461 tatagtgggt taatgaattt aacttcttgg aatcaaggtg gactaggcat ctttacaatt
    41521 cccaactata ttagaccaga tggtgattta acagatgtga ttaatgtatt gattgggatc
    41581 gccattgcga tggtggtatc ctttgcgctg acttttttct tttggaagga ggaagcaggt
    41641 gaaacagatg acagacagaa aagatcaggt aaagaaattg taaaaacacc gatacaagga
    41701 caaatcgctc cactgaaagc agcaaaggat gcagcttttg cacaaggaac actaggtcga
    41761 ggaatcttga tctaccctga aaaaggagaa gtacgtgccc cttttgacgg aacagtcatg
    41821 accctgttcc ccacgaaaca tgcaatcgga atggtttctg aaacaggtct ggaattgctg
    41881 attcatgtcg gattggatac tgttcagttg gaagggaaat attttgaaag cttggtgcag
    41941 caaggagaaa gagtgaaaca aggcgatctg ttgctccgct tcgacaaaaa gaaaatcgaa
    42001 aaggaaggat acagtttaga aacacctgta atcgtcacca attacatgga ttatttggat
    42061 attttggaaa atcaagggga gacggtcggg ccagacgatg cacttatcac cgcactgacc
    42121 tgaacggtta ggtgaaagaa tggaatagac ttaactattc tttttagtcc acttctttat
    42181 tttcaaaatt gaaaggctct ttcatgatgg ctgagctgat agggcgttta tcaaattttt
    42241 gtcctacaga aattagatgg actaaattct gttgataatt ttctgcaaaa acacaactat
    42301 ataacacgtc tagaagataa caaatcgatg tattgatcgt aaaattacca atttttgaat
    42361 acagtcgttc gcgtgtcgta agtcgcaaag cggctgtact cattgaggat agcgttgaat
    42421 caccgatact ggtcaacgct aaaattggaa catgattttg tttcaatatt tctgcggtac
    42481 gaaggatcac attgttttca cccgtataag aaatcagaat cccgcacata tcactcgtgc
    42541 aattgtacgc ttcatagaac gattcaccaa aagtggtgac aatcgtgaca tccattttga
    42601 tgcgcttcat tttcagcatg aaatcttgag aaatcaaagt attcgagtta ctggcgaaaa
    42661 tcacgatttt ttttgcttga agcattagtt gtttggcttt ttgcagttgg tcatgatgaa
    42721 tgagagaaag tgtatcttga atcgtcatct gttctaaaga agccatttta tttgcgatcg
    42781 tcataatacc gtctgtggtg gaaaaaggaa gattcgcatc tacgtcttga aaattccctt
    42841 caagataggc tgtttcagct aaaaaagcat tacgaaaact gacccagcca tcaaaaccca
    42901 ttttttttgc tacacggatg agtgtggacg ggtggacata acatcgctca gcaatctctt
    42961 ggatggtcat ttcgccaagt gctggagaat cgcttaagag aaactgaatc acttcatttt
    43021 ctgaaggaga aaaggagatt tctttgattt tttcacgtaa taacatgtag ataccttctt
    43081 ctagtttttt tacgtaaatt ataacttttt tgaaaatgat ttgtaaacgg atttatgtta
    43141 tatagcttaa taaagtcatt ttttgacaag atatttacaa aaatccagta gaaaacacta
    43201 acttttgtaa atgttactgg aaagaaacga atttctattg tttgttttgt ttacaaaaaa
    43261 gataataaaa gtgtaaaaag caaaggagtg agaacatggc aaaaggaatc aaaatcgcta
    43321 cgattggtgg aggcagcagt tacacccccg agttgatgga aggatttatc aaaagatatg
    43381 aggaattacc gatacgagaa atctggctcg tagatgtaga agaaggaaaa gaaaagcttg
    43441 agatcgtcag tcagatgtct cagcgtatgt gggatgcttc tccgtatgaa gtcaagatct
    43501 atgcaacttt ggatcgggaa gaagcattga aagatgcgga ttttgttacg actcagtttc
    43561 gtgtcggtca attagatgca cgaatcaaag acgagcggat ccctagttat tatgggatga
    43621 ttgggcaaga aacaaatggt gctggcggga tattcaaagc ttttcgtacc gttccagtgg
    43681 ttttggcaat cgttgaagac atgaagcgtt tatgtccaaa tgcttggctg atcaatttcg
    43741 cgaacccaag cgggatggtg acagaagcag ttatcagata tggcaaatgg gataaagtga
    43801 tcggattatg caatgtgcca gtaatggcga cgatgacaga accagcaatg cttggcaaga
    43861 aaaaagaaga gctgatctac aagtttgccg gtctaaatca cttccattgg cacaaagtag
    43921 cagataataa aggaaatgac cgcacagcag atttgattga tcgtttatac gatgaagaca
    43981 atggattgcc gaaaaatatc tttgacatcc cgtttttcaa agaacaatta aaacaaatga
    44041 acatgatccc ttgtggctac caccgctatt actaccgtga agaagaaatg ttggaacatg
    44101 ctttagaaga atatcaaacg attggtacaa gagcgcaaca agtgaaagaa acagaagcag
    44161 agctgtttga attatacaaa gatccagaat tggatcataa acctgaacaa ttgcaaaaac
    44221 gaggtggtgc ttattattca gatgctgcct gtgaaacgat tgcttcgatc tatggaaata
    44281 aagaaacaca gatcgtggtg tctacaaaga atgatggagc tgttcctgat ctgccggcag
    44341 attgtgtagt agaagtcact gcctatgttg gcgcacaagg cgcacgaaat gtagcgtttg
    44401 gttcccttcc tgctgctgaa agaggctggt tgcaagtaat gaagaatatg gaattgctga
    44461 cgatcgaagc agccgtgact ggtgattatg gaacagcttt acaagcgttt acgatcaatc
    44521 cgcttatacg atcaggaaag acagcaaaac ggatcatgga tgagttgttt attgcacatc
    44581 agcagtattt accgcaattc aaggaaacaa tcagccggtt aaaagcagaa ggaatcgaag
    44641 tccaagatga actggcaaga gaattgtcaa gcaatacaca tgtaatggag gaagtatgat
    44701 gggattcaga aaagattttt tatggggcgg tgctacagca gccaatcaat gcgagggtgg
    44761 ttatgatgaa ggcggacgtg ggttagcgaa cgtagatgtt gtgccaatcg gagaagaccg
    44821 ttttcctgtc attactggaa aaaagaaaat gtttgaattt gataaagatc atttttatcc
    44881 agcaaaaatt gcgatcgata tgtatcatca ttataaggaa gatattgctt tgtttgcaga
    44941 aatggggttc aagacttatc ggatgtccat tgcttggagt cgtatttttc caatgggcga
    45001 tgaaaatgag ccaaatgaat ctggtttgaa attttatgag gatgtcttta aagaatgtca
    45061 aaagtacggg atcgagccgc ttgtgacgat tacacatttt gattgtccga tgcatttgat
    45121 caaagaatat ggtgcgtggc gttctagaga actcgttggt ttttatgaaa atctgtgccg
    45181 agtcatcttc aatcgctata aaggacttgt caaatattgg ttgacattca atgagatcaa
    45241 tatgatcctt catgcaccat tcatgggcgc agggctgtat tttgaagaag gagaaaatga
    45301 agaacaaatc aaatatcaag cggcacatca tgagttggtt gcaagtgcca tcgcaacgaa
    45361 gattgctcat gaagtagatc cggagaacaa agtaggctgt atgctggcag caggagcata
    45421 ttatccatac acttgcaatc ctgaagatgt ttgggcttct agaaaatcag atcgagaaaa
    45481 ttatttcttc attgatgtcc agtcacgagg agaatatccc gcttatgcat tgaaagaaat
    45541 ggaacgaaat ggcattcaga tcaaaatgga acctggggat gccgcattgc tgaaagaaca
    45601 tactgttgat tttatctcct tttcttatta ttcttctcga gtttcgacta ctgacaacga
    45661 actcttggaa cagactgcag gaaatatctt tgcttctgtc aaaaatccat atctggaagc
    45721 aagtgaatgg ggttggcaaa ttgatccatt aggcttgaga ataacgatga atgatattta
    45781 tgatcgttat caaaaaccac tatttattgt agaaaacggc ttaggtgcag tcgatacgcc
    45841 cgatgagaat ggttatgtgg aagatgacta tcgaatcgac tatctggcag cacatatcca
    45901 ggcaatgaaa gatacagtag aattagatgg agtcgatcta ttaggctata cgacttgggg
    45961 atgtattgat ttagtatcag ctggtacagg tgagatgaag aaaaggtacg gattcattta
    46021 tgtcgatcgt gacaacgaag gaaatggcac attagcccgt tcgaagaaga aatcattcaa
    46081 ctggtataaa aaagtaattg attcaaatgg agaaaatctt tcgaatgatt gatcaatgat
    46141 ttgtaaaagt ctattgtttt tcagcggatt tttcgagtat aataaagcta ttcgagaaac
    46201 gcaagcagaa caatagactt tttttcgcat tggctgtaaa gtatgcttac ttgattaagt
    46261 aaaggagaat ctacatatgt atgatgtaat cgttattggc gcaggtcctg ctgggatgac
    46321 tgctgcttta tatgcttcac gttcaaactt atccgtattg atgatcgaac aaggcgcccc
    46381 tggcggccaa atgaacaata cggcagaaat cgaaaactat cctggtttcg attcaatcat
    46441 gggtcctgat ctagcttata agatgtatga aggtgtttca agatttggga cagaaaatgc
    46501 ttatggaatc gtgcaagata tcaaggatca cggcagccac aaagaagtta tttgtgaaga
    46561 taaaacttac gaaggaaaaa cagtcattat cgcaacaggc tgtatccacc gtaaattagg
    46621 cgtacctggc gaggaagaat ttgctggacg tggcgtttct tactgtgcag tttgtgatgg
    46681 tgcgtttttc cgtaacaaac gtctagtagt gatcggagga ggagactcag cagtagaaga
    46741 agccatctat ttgacacaat ttgcttctga agtagtcatc gtccaccgta gagatgaatt
    46801 acgtgcacaa aagatcatcc aagaccgtgc atttgcgaat gaaaaaattt cctttatgtg
    46861 ggatacagtc gttgacgaaa tcgttgggaa tgaaatggta gtgacaggtg tgaaagcacg
    46921 taatgtcaaa accggcaatg agtttgattt ggcagcagac ggagtattca tctatgttgg
    46981 actggatcca ttaactgcac catttagaga agcagggttg acgaacgaag ctggctggat
    47041 tccaacagac aacgaaatga agacgaatat accaggcgtt tttgccatcg gagatgttcg
    47101 tgaaaaagat ttgcgacaaa tcactactgc tgttggtgat ggtgggatcg ctggacaaca
    47161 agtgtataaa tacttggaat ctttagaaga aacaactgca taagtttaaa aagagtggaa
    47221 gaacggtttc aattgttctt ttactctttt ttttcgcgtg aaatctactg aatccgattt
    47281 atgcgaatac ttgcaaccgt gcttgataaa agaatccttt cttgatttaa gcgtttttta
    47341 gacctcgtac tttcatatct aataagtgaa tgctatactt attaagaacc atatttcaga
    47401 aagaggtgtt attttcatgt cttgggaaca agtgtatgaa caatgggtac atgaagaaaa
    47461 tttagaagaa aacttaaaaa aacaattaat tgatctgggt gaagatcctg aaaaacttga
    47521 agatgctttt tatgcaccgt tggaattcgg tactgcaggc atgcggggaa tcttaggacc
    47581 tgggatcaat cgaatgaaca tctatacggt aagacaagca acagaaggac ttgcacgttt
    47641 catggataca caaggtgaag aaacaaaacg ccgaggtgtc gctatcgctt atgactcacg
    47701 ccatcaatca ccagaatttg ccatggaagc agccaaaaca ttagcacatc acaatatccc
    47761 ttcttatgta ttcgaaagtt tacgtccaac accagagctt tcttttgcag tccgtcattt
    47821 gaagacgttt gcgggaatca tggtaactgc atcccacaat ccagcagctt acaacggata
    47881 taaagtctac ggagaagatg ggggacaaat gcctcctgca gacgcagatg cattgacgaa
    47941 atatgtccgt gaagtcagca atccgttaaa agttgaagta ttatctgacg acgaagctga
    48001 acatagcgga ttgatcacga tcatcggaga agaagtggat gccgcttatc tagaagaaat
    48061 caaagcagta acgattgatc atgaattggt ggaaacaatg ggtaaagatt tgaaacttgt
    48121 gtacacacca cttcacggaa caggaaaaat gttgggcgaa cgtgcgttga aacaagctgg
    48181 attcgaacaa ttcgtactag ttccagaaca agctgtcgca gacccggatt tcactacagt
    48241 caaatcaccg aatccagaag aacactctgc tttcgagtat gcgatgcgac ttggcgagaa
    48301 agaaggcgct gacttactga ttgcaacaga tcctgatgca gaccgtttag gcgcagccgt
    48361 tcgtttgcca aatggctcct atgaagtatt gacagggaac caaatcggag ccctgtttgc
    48421 tcaatatatt ttggaagcac accaatcgcg aggcacttta cctgaaaatg cagcggtatt
    48481 gaaatcaatc gtttctagcg aattgcctac agcaattgcg gaacactatg gggctaccat
    48541 gttcaatgta ttgacaggat tcaaattcat cgctgaaaaa attcaacaat ttgaagaaga
    48601 tcattcccat acttttatgt tcggattcga agaaagttac ggttatttag ttaaaccttt
    48661 cgttcgcgac aaagacgcga ttcaagcatt gctcttatta gcagaagtag cagcttacta
    48721 taaaaaacaa ggcaaaacgt tgtatgacgg cttgcaaacg atttttgaaa catatggcta
    48781 ctacgcagaa aaaacgattt ctgtgacaat gagcggacaa gaaggttctg caaaaatctc
    48841 tgctttgatg gaaaaattcc gtgaagaagc accgacagaa tttgccggag caaaagtcat
    48901 ccaaacagaa gacttcaaag agttgacgag aacagaccgt gaaggaaacg tagaaaaact
    48961 aacgacaccg ccatctgacg tattgaagta tacgctggaa gaaaatggct ggatcgctat
    49021 ccgtccttca ggaactgagc cgaaaatcaa attttatatc ggtgtaaaag gaaactcttc
    49081 agaagacgca gctgaaaaag tagccgctta tgaagcgatt atcaaaaaaa tgacagaaga
    49141 ataaaaaaac ttgagactga tggaaaaagt ggtaaacttt agaagtcagt cttttttcaa
    49201 gttggaggtg aatggattgc cagacacgca aaaaacaaaa gtagagaaag tcagccaact
    49261 attcaaaatg ttgagtgacc ccactcgtct caaaattctg ctgtatctga aagacgggga
    49321 acaaaatgtg acagcaatca cccaagcagt agaaatggaa caatctgctg tatcgcatca
    49381 actgcgttta ttaagagaaa accatgtcgt caagtcccat cgtgagggaa aagcgatttt
    49441 gtatagtctt gatgattctc acgtactgga tattttgaac cagacgctca aacatgtgga
    49501 acatcaataa cgataggtgc aaatagagac aaactggact gtatcaacga atcttcttcg
    49561 ctgacacagt ccagtttttt taagaaaaag acaagaaaaa ctgttagtct gtttcttcgg
    49621 tggtttcagt tccataataa ctatgatctt ctaggtctaa agcattcaaa ataagtgaag
    49681 ctgtttcttc gatagataaa gaagcgacat tgattactac gcagcccaat ttttcataaa
    49741 gatcattcgc aaaatcgagt tcagctcgta ttttttcgat atcggaataa gcagtatcag
    49801 gatttaatcc gtaagagcgc atccgttctt tacggatatt gtttaaaata tctgggttat
    49861 tcgtcagtcc cacgattttt ttaggatcga tctcccaaag ctgtttggga atatgtgctt
    49921 gtgggatcaa aggtagattg gcaaccttta aatttttgtt agctaaaaac aagctcaaag
    49981 gcgttttgga agttctggat acgcctagca aaacgacatc tgcttctaga aacccacgag
    50041 gatctttccc gtcatcgtat tttacagcaa attccattgc tttgatccgt ttgaaatagt
    50101 tctcattcaa taaatgaagg gcgccaggtt gccgaatggg cttgatacca gttaagcgct
    50161 cgatttctga tatcggcgga gtcatcacat caaaactaaa taattgatgt tcttcacaaa
    50221 aagaacgcgt catctcgatc aattcttgat tgatcaatgt gtgcaggaca agggcttttt
    50281 cttttagtgc atcttgcagt gcctgcatca atgttttctc atctgtcaca aatgttctgc
    50341 ggaataaatt gaactcaacg gtaggatatt gggccatagt ggcttgcgct aattttgtcg
    50401 cagtttctcc agcagagtca gagatgacaa aaaaagtaac gatttctgta gaatcggaag
    50461 acatggataa aacctcactt gcattttttt tatgtttatt ataccatact ctagaatgtg
    50521 tacttcgtaa tcattttgat ttggaggaat aagtcatgaa aaaacagaca ttgattgaac
    50581 aatcactaga aacattgaaa aataacggtt ttaaatatac taaaaaaaga gaagcattgt
    50641 taacttattt agtgaagcgc aatcgctacg tatccgctaa agaagttttt gactatatga
    50701 atcaggaatt caaaggagta agttacgata cgatttatcg aaatctccat gattttgcag
    50761 aaatcgattt actggaagaa accgatttaa atggagagat gaagtttcgt tttcattgct
    50821 gtcaagggga aatcggccat caccatcact ttatctgtac ggtgtgcgga acaacgaaag
    50881 aaatccatat gtgtccaatg aattatttcg aagaacagct cggtggatgt acgatcgaag
    50941 ggcatagatt cgagattttc ggaagatgtg aaaattgtca ataaggattt aaataaaata
    51001 acatttgata attttaaaaa aaagcaagat ttccttgacg gtcaaaacag cattagatat
    51061 aatatttaca ggacagtctt gttttttgag atatatttca ataacaatta cggttacttt
    51121 ttaagctcgg agggagggaa ttaacatgtc aaaaacagtc gttcgcaaaa acgaatcact
    51181 tgacgatgct cttcgtcgct tcaaacgttc cgtgtcaaaa gcgggtactt tacaagaatc
    51241 tcgtaaacgt gaattctacg aaaaaccaag tgtaagacgc aagaaaaaat ctgaagcagc
    51301 tagaaaacgc aaaaaattct agttctgtga tgaattggag ttggtagtgt gtcactacta
    51361 agtagattaa acgatgacat gaaaacagcg atgaaagcga aagataagga atctttacaa
    51421 gtcatccgaa tgatcaagtc atctatacaa aacgagcaga ttaaagaagg tcacgacttg
    51481 acagaagaag aagaattaac ggtgttgtct cgcgaaatga aacagcgacg tgattctttg
    51541 catgagtttg aagaagcagg acgtgacgat ttagctgaaa aagtaaaaag tgaaattgtg
    51601 atagtcgaaa aatacatgcc ggaacaactt tccgacgaag aaattcgaca acttgttcaa
    51661 gaagcaatca cacaaactgg tgcttcatca atgaaagaat ttggcaaagt catgggtgcg
    51721 atcatgccta aagtcaaagg aaaagcagat ggaaaccaag taaatgccat tgtgaaagaa
    51781 ctattacaat cttaatttta tcatttaaac tgcggacaat cattgtccgc agtttttttg
    51841 tgcgcgtaaa aaagagaaca aaaaaatagc tagacgaaag aataggattc tttcatctag
    51901 ctggtttttt cctgtttaat atttcttatg ttaaattgtg tttgatttgg ttattcttct
    51961 ggtagttcat ttgcttcttg tttataccct gataggcgat aggcgtaata aaacagtagg
    52021 ctgccagcgt aaccaagtaa cgttgggacc atccagccaa gtcctaatgc agcaaaagga
    52081 acgtgatgat gataaaattc gagcatgctt gctacaactc tttgttgact cactaaagca
    52141 ggcgaatttg ccagcatatc caatacggca ggaacagcag caaacaacat cgttacttga
    52201 tagacaaatg gtgtcttttg gaaaaatttt gctgttaagg aaagcaagat caacgcaagc
    52261 gacaatggat acaaaagcat caatactggt aaagaccatt ggatgatatt gtctaaacca
    52321 gcatttgcaa cgacaaaaga gacgaaagtc gttaaccgca gccatgtcat ataactgact
    52381 ttagggaaca gtttatggaa atcttgcgca aaagaaacaa cgagtcccat agcggtagtg
    52441 aagacaccta atgtgaccat cactcctaag aagctagcgc cgaagttacc taaataaaaa
    52501 ttagtgatct gagaaagtgc agttccgcca ttttctgata aagacatctt attcaaactc
    52561 atcgcaccga gaagaacaag accaaaatag atcatgactt ctagcgcaac gctcaggcta
    52621 ccagcttttg ctgttaattc tgtgactttt ttatctttga aaccaaggtc acggactgca
    52681 tggacaaaag tgacacttaa ggcaagcaag gctactgcat caaccgtgtt ataaccttct
    52741 aggacaccat ttgttaaagc gtttgtttgg taagtatctg cagcagattg atttagattt
    52801 cccattgggt ggaataaaga aacgacaaaa atgattgcta acaatgcaag aaacaaggag
    52861 tttagatact ttccgacgta tttgaccaac cgtgtgggat ggacagtaag gaaataagca
    52921 agtaaaaaga aaagagcaga gaataaaaac atacctaatg aattatattt ttcaggcaaa
    52981 aatggtttag cagccatttc aaaagcagta gcagctgtcc gtggtgtacc gaaaaatggt
    53041 ccgatcgtca aatgaacaag gattaagaac aaggcagcat accattttcc gacaggttta
    53101 gctaagtcat acagaccatc actttttgtc actactacag ctaagatagc tagtaatggg
    53161 aaaagagcgc ccgagatggc aaatcctacg ccagcactga cccagtttgc gccagccatt
    53221 tgacctaagt ggacaggaaa gattagatta cctgacccga agaacatccc gaagataagt
    53281 gaactgacca tcaatagttg tttccatgaa taagtttttg tttcttccat aaatttttcc
    53341 tccaataatt atcattttga ttgacgatat aaacgttgca gcaattagta atgccactaa
    53401 tatcagattc catgaaaacc accaccttaa aatataaaaa aagccctttt ccacttggga
    53461 aaagggctct agattctaga acggtaccac cttttttcgc ttaaaaaagc ttcttcattc
    53521 acggacgctt tttgataaag ttatccgcta gcctgataat ggaggcagcc acaatgatct
    53581 acgttttcga cattgactcg gaaatgatgt tcgtctattc gatttattgt catttctcac
    53641 ttacatgact cactgggaat aaatcgttga atagcctact gttttcctcg acgctttgct
    53701 gtatgtttat ttgttgacgt aataatacac ctgttttttt tgaaatgcaa gaatatttta
    53761 actattttgt tttctttttt tgaaacaaga aaaataccta gagaatacct gctgaatgaa
    53821 acggaatatt ttgttctcca ctttcatata acttacattc tcagcttctt tttatcaaaa
    53881 cgagaccttt agcgaatgga aacggctatt ttttaacgtt tcttggtacg tatggttaaa
    53941 cgactctttt acaacctttt cttatttgct atatagtttc ttctgagtat ggtaaaatag
    54001 gaaagaatga atcgaaaaaa aggggatgtc tatttttgac ggaagagtct agttctttag
    54061 agattagatt gacagctgct gatgatgtca gcatgctttt aggtgcacac gacaagcata
    54121 taaaactgat cgaggaaaca acggaaacaa ccatccatac acgtggagaa atcattcaga
    54181 tcattggtga gcaatcccag atttccttgg ctgcctcagt cattcggaca ttacaggaat
    54241 tgatcaaacg aggaatccac gtaagtacgc cagatgttgt gacggcattg aagatggggc
    54301 aaaaaggtac attagattat tttgttgaga tgtatgagga agagatcgtc aaagaccgta
    54361 atggaaaacc tatacgggta aaaaacagcg gtcaaaagaa atacgttgaa tcggtagcca
    54421 aacatgacat cgtatttggt gtagggccag ccggaacagg gaaaacgttt cttgccgtag
    54481 tattagcaat tgctgcccta aaaaaaggcg aagtgcaaaa aatcattttg acgcggcccg
    54541 ctgtggaggc aggggaaaac ctaggctttc tacccgggga tctgaaagaa aaagtggatc
    54601 cttatctgcg gcctgtttat gatgctttat accaaatttt tggattggat catacgaacc
    54661 gattgatgga acgaggcgtg atcgaaatcg cacctttagc ttacatgcgg gggcggacat
    54721 tggatgatgc attcgttatc ttggacgaag cacaaaacac gacagtcgct cagatgaaaa
    54781 tgttcttgac ccgtctcggt tatcaatcaa aaatgattgt caatggggat acaagtcaga
    54841 tagacttgcc tcgtgggacg acaagtggtc ttgttcatgc agaacgaaca ttaaagcaaa
    54901 tcaaaaaaat cgattttgtt aattttgaag caagtgacgt tgttcggcac cctgtagttg
    54961 ccgaaatcat caaagcttat gaaaaggcgg atcttcatca agaataagct ttgcttagga
    55021 ggataagcac atgttgaata aaacactgca gaaactacaa aaaaaactcg gaaaggcagc
    55081 attgcctttc cttctgttct tgttttttat cattgtctgc ggcgttacat ttagtagtgt
    55141 caaacaaaag gccaatgatt tcagagaagg ccaagtagca gaagagagta tccgtgcgaa
    55201 taaaacgatt gagaacacgg aagaaaccga acaaagaaga aaactggcag cagaagcagt
    55261 gactccagaa tatacttatc aaaaagatct ggcagatgac cagaacaatc ggatcaagca
    55321 attattcgaa ttgatcgata agacgaatga taccatcaac aaatcttata atgacaaggt
    55381 agataaggcg aaggaagatg aaaatatccc gaaacctact acagaagagc ggattgctac
    55441 actgaagaaa aattttgaaa acgtgaatgc agaaaacgtt gcgttttacc aaaaactgcc
    55501 gaacaatttt tattcgacga tatttgaaat gactgaaacg gaaattcaca cggttaggga
    55561 tgaaagtttg aagctcattg acgaacagat gagtaaacaa gttcgtgaaa gcgaattgga
    55621 agcttttaaa caagaagcag aagatcagat tcaatatttg aatgtcacaa cagagcagca
    55681 acaaatgatt cgctacttag tggatcaagg cattgtagtt aatgatgtat tgaatgagaa
    55741 aaagacagaa gaattaaaac aatctgcacg agaagctgta caaccagtga tgatcttcca
    55801 aggagaaatt attgttcgcg aaggaaatca aattgatgct tcagcgatga aaaaattgga
    55861 attactagga ttgacgaatc aaacgacttc tattttccca ctcattgcca tggttttagc
    55921 tgttttgctt caaatcggtg tactgattta taattcactt caattccaaa atgcaggaga
    55981 aagaacaaaa tacgtacttt tctacgtgac ggcaatgtca gtaagcgtcg tactaatgaa
    56041 atttttccaa ctcttccaaa cagaacaagc tgcttatatt ccgctgtttt accccgcggc
    56101 ttttgctcca cttgttttaa gctttttctt gaatcgaaga gcagggatca tggctggtat
    56161 ttttcaagca gtatccgcac ttttcatttt ttatgattcg attggcacga actttctgac
    56221 agttattttg atgtcctatg tattttctgg tctcatggca acgatcgtca gacgcaaacg
    56281 gatctcagaa caagggttat ccgctgctat gtgggtcatt atttttcctg tgatgatgga
    56341 tgtcattttg attatctacc aaggaatgag ctttggggat gcaacgactt ggttaacgct
    56401 agtatgcgga ttcacaggtg cactgttctc attcttgctg acgataggtc tgcaccccta
    56461 tattgaattg atggtcaatg atgatagtgt gatcgtatta aatgaactca gcaatcctaa
    56521 tcatccttta ttgaaacagt tgctggaaga agcaccaggc acgtatcacc atagcatgat
    56581 ggtagccaat ctaagtgcta atgctgtagc agaaatcggt ggacgttctt tactaactcg
    56641 agtagcttgc tattatcatg atatcggcaa gatcaaacac gccagctttt tcgttgagaa
    56701 cttgccttca ggagcggaaa atccgcacaa tttcttattg ccagaagaca gtaaacatat
    56761 tatctttgga catgtgacag atggtgccaa aatattggaa gattataata tgccgcaaat
    56821 ggtgatcgat atttgcagac agcatcatgg aaccacgctg atgcgttatt tctacgttaa
    56881 ggcaaaggaa cgcaacccgg aagtcacgga agagcaattc cgttatcctg gaccaaaacc
    56941 tcaaagccgt gaagcaggaa tcgtcaatat agctgacagt tgtgaagcgg cagtacgagc
    57001 aatggaccat ccaacgagcg aaaaaatcga aagttttgtc cataatctta ttgaagagcg
    57061 tatttccgat ggacaattgg acgacagtgg attgacgtta aaagaaatcc gtaaagtaga
    57121 aaaatcattg atcagcggtt taagcagtac cttccattct cggatcaaat atcctaaaat
    57181 gaaatcggaa gttgagaaga taaaagaaga acaagaagaa tagaaagaag cgatgtataa
    57241 tggatattac tttcatggat gaaacaaacc aagtctcaga agagaaaatg aaagaaatcg
    57301 acgacttgct gcaatttgca gcatcatatt tagagttgcc agaagaaaca gaaatgtctg
    57361 ttactttcat ggacaatgca gcgatccaag taatcaatcg tgattaccgt ggaaaagatg
    57421 caccgacaga cgtcatcagt tttgccttgg aagaagaggg cgaagacgaa atcccagtga
    57481 tttttgaaga tggagagaat ccattgcctc gtgtactggg agacatcatg atctctactg
    57541 aacgtgctgc agagcaagca gaagcttacg gccattcgta tgatcgggaa cttggctttt
    57601 tagcggttca tggattcttg catatcaacg ggtatgacca tatgacacca gaggatgaga
    57661 aagaaatgtt tggtttacag aaagagatct tagatgccta tggacttaaa agataaaaac
    57721 gtagagaaaa acaaacattt cctgatgtcc gtggaatttg ccgtccaagg agtcaaaacc
    57781 gtttttgagg aagaacgcaa catgaggaaa catgttgcgt tcggaatcct cgctttgttt
    57841 atgggcgtga ttttccagct tgatcggata gaatggttat ggctgctttt agctgttttt
    57901 ctcgtatgga tagtagagat catcaatact gtttttgaaa atgtcgtgga catgtttacg
    57961 gattttcatt ttcatccgat tgggaaaaaa atcaaagata tggcagctgg agcagtttta
    58021 gtgaccgctt gtttttccgt catcgttggg ttgattttat ttgtccctaa aatatatcat
    58081 ttgttgttta attaaaaagg agaacgtata tgccagaaca taaatcaggg tttgtcgcaa
    58141 tcgtcggccg cccgaatgta ggaaaatcca cattattgaa tcgaatcgtg ggtcaaaaaa
    58201 ttgccatcat gagtgataag gcgcagacaa ctagaaataa aatccaagga gtatatacta
    58261 caccagaagc tcagttgatt tttattgaca caccaggaat ccataaacca aagcatcgtt
    58321 taggagattt tatggtagaa gcagcttaca gtgcgttgaa agaagtggac gcggtcttat
    58381 ttatgatcag cgctgatcaa aaacgcggtc ggggagacga ttttattatt gaacgtctaa
    58441 aaaacgtgca ttctcctgtt tatctgatta tcaataaaat cgataaaatc catccagacg
    58501 agttgttggg aatcatcgaa gattattcaa cgcagatgcc gtttgcacaa gtgattccaa
    58561 tttctgctac agaaggaaac aacgtcgaac gtttgatgga tgtattagtc agtgaaatgc
    58621 cagagggccc acaatatttt ccagatgatc aagtgactga tcatcctgaa tacttcatcg
    58681 tttctgaatt gatccgtgag aaagtcttgt ttttaacacg agacgaagtg cctcattctg
    58741 tcgcagtcgt tgttgattcg atgaagcgaa acgagaatga taaaatccat atccaggcta
    58801 cgattattgt cgaaagagat agccaaaaag ggatcattat cggcaaaggc ggaaaaatgc
    58861 tgaagcaagt aggaacgaaa gcgagaaaag atatcgaaaa tcttttagga gacaaagtct
    58921 ttctagaact ttgggtcaaa gttcaaaaag actggcgaga caaaaaagtc tatctgcaag
    58981 acttcggcta ccgaaaagac gaatattgat attctgagct tcttgtaagt taggtataga
    59041 aataaactgg ataaaaatcc gcgtgttgag aaaagctgcg gaagatcgca acataaatga
    59101 tctggatcgg cagaatctgc ttttccagat ttatttttta ggagggagaa tatgagccag
    59161 cttgcagaat caaaaggctt gattttatct agccgtaatt acaaagaaaa agataaatta
    59221 gtcaaaatct ttacggaatc ttctggcaaa atgatgtttt atatcaaagg gatccatcgg
    59281 caaaatcagc ccttagctcc ggctttgctc ccttttactg aagcagttta tatcgggaat
    59341 tttcgaagtg aaggtttgtc atttttaagc agtgtcaaag atgtccacgc gtttcgacac
    59401 atccaagaag acatcttttt gagcggctat ggcacatatt tattgaatct agtagatgcg
    59461 gcaatcgaag atcatcagta cgacccgcat ttgttccagt ttacgcaaca agcactgcaa
    59521 cggatggacc aaggagatga tgcagaaatc atcacgaata tttttgaagt ccaaatactg
    59581 caacgcttcg gaattgcacc aatctggaca cactgcgtcg tatgtgggga aacaaaagga
    59641 aaatttgact attcttccaa atatggtggt gtgatatgcg aaagacactg gtcgatggat
    59701 gatcaccgtt atcatgcaga tcctcgagct gtttatttcg ttcggatgtt ttcagctatt
    59761 tcttatgata aaatcagtgg aatccatctg aaagaagaaa ccaaacaagc aatccgtgaa
    59821 ctcatcgacc agctgtatga tgaatatgtc ggtatccatt tgaaaagcaa aaagttcatt
    59881 gatcaaatga agtcttgggc acacgtatta aagacgtcag agaaagacat gtctgaaaaa
    59941 gatctaccta aaaaagaaga atagtaaatg aaacatacaa caaaaaatca aaaccatttg
    60001 acaaacacag ggagttccgt ctattattaa ccgtagatca aatagatcgt tcactgagag
    60061 gatctattat agaaacaaga aaactgcaaa atgaatacgt acattgacca agatcagtaa
    60121 aaaacacgtg gtttagcgag ttcgggagag tgggagccgg acccaaacga tttttgaaga
    60181 ggcacttgcg agtacgataa atgaagctgc cgaatcttta ttcggaagta gggtggaacc
    60241 gcgaattatt cgtccctatg tctgtaatca gacataggga ttttttgtcg ttttctttcc
    60301 tgtattctta tttgacagca acgctttaaa attgaaaggg gcaaaacaga tgagtaaaaa
    60361 attgaccgtc caagatatga ttttaacatt acaaaaattt tggtcatcaa acggctgcat
    60421 gctgatgcaa gcgtatgaca cagaaaaagg agcaggtacg atgagcccat ataccttttt
    60481 acgggcaatc ggaccagaac catggaatgc tgcttacgta gagccatctc gccgaccagc
    60541 tgatggacgt tatggcgaaa acccaaaccg tttgtatcag catcatcaat tccaagtcgt
    60601 gatgaaacct tcacctgaga atatccaaga gctttattta gaaagcttgc gccttttagg
    60661 aatcgatcca ctagaacacg acatccgttt tgttgaagac aactgggaga acccatccat
    60721 gggctgtgcc ggtgtgggtt gggaagtatg gcttgacgga atggaaatca cacaattcac
    60781 gtacttccaa caagttggtg gactgccttg taaaccagta acttctgaga tcacttatgg
    60841 attagaacgt cttgcttctt atatccaaga agttgaaagt gtctatgatt tagaatgggc
    60901 tgatggcgtg aaatatggcg agatcttcaa acaaccagaa tatgaacatt ctaaatattc
    60961 ttttgaagta agcgaccaag acttgctact aagcaacttt gatcgttttg aaaaagaagc
    61021 taaacgctgt atcgatgaaa atcttgttca tccggcgtat gattatatct tgaaatgtag
    61081 ccatacattc aacttattag acgcccgcgg tgcagtatcc gtaacagagc gtgccggtta
    61141 tctttctcgc atccgcaaca tggctcgtgc tgtagccaaa atctttgtgg cagaacgcga
    61201 aaaattagga ttccctttgt tgaataaaaa cacagcaaat ccagaaaacg tgaaggaggc
    61261 tgaataagat ggcaaaagac ttattacttg aaatcgggct ggaagaaatg cctgctcatg
    61321 ttgtcacacc aagcatgaaa caattagaag aaaaaacagc aaaattttta gatgaaaacc
    61381 aattgactta tgatacgatc gaaacatttt ccacaccgcg ccgtttagca atcaaagtaa
    61441 caaacattcc agaacgacaa gcggacagtg aagaagaagt caaaggacca gccaaaaaaa
    61501 ttgctttgga cgcagatgga aactggacga aagcagcgga aggatttgtc cgcggacaag
    61561 gtctgacgac agacgctatc acttttagag aattaaaagg tgtggaatat gtctatgtaa
    61621 cgaaatacac tcatggtaag gaatccaaag aagtattgac aggtttagca gatgtcatta
    61681 aaagcctgac tttccctgta acgatgcatt gggcagaata cgattttgaa tatatccgcc
    61741 ctattcactg gatcgtggca ttgttagatg acgaagtaat cccattcgaa atcttggatg
    61801 tcaaaacagg cagagcctct cgaggtcatc gtttcttagg cgaagatgtg acatttgcgc
    61861 atgcaaaaga atatgaagaa aaattgaatg aacaattcgt cattgcgtct ccgcaaaaaa
    61921 gacaagaaat gatcgttaca caagccaatg aattagccga aaaaaatcat tgggttattg
    61981 atctagacga agatttacta gaagaagtca acaatttagt cgaatatcca actgtctttt
    62041 ctggcgactt cgaagaaaaa tatctttctg ttcctgaaga agtactagtc acttctatga
    62101 aagaacatca acgttatttc gaggtacgga atgatcaagg tatgctgctt cctcatttta
    62161 tttctgctcg taatggtgat cgggtaaaat tggaaaatgt ggttcgaggc aatcaaaaag
    62221 tattgacggc tcgtttagaa gatgcggaat tcttttataa tgaagacaag aaagcttcaa
    62281 tcgaccaata cgttgaaaaa ctaaaaactg ttactttcca tgaaaaaatc ggtagtatct
    62341 atgagaaaat gcaacgggta caagtcattg cccgtatcat tggcgaacaa gtaggactat
    62401 ctgaggaaga attgatggat ctgcaacgag ctgctgaaat ctataaattt gatctagtaa
    62461 ccaacatggt aggggaattt cctgaactgc aagggatcat gggcgaaaaa tatgctctgc
    62521 tgaaaggcga gaaacctgct gtagcgacag cgattcgtga gcattacatg cctatatcca
    62581 gtgaaggaga gctacctcag tctacagtag gttctgtttt agcgattgca gataaattag
    62641 atagcatctt ttctttcttt gctgttggga tgatcccaag cggttcaaac gatccttatg
    62701 ccttacgtcg ccaagcatac ggtgtcgttc ggatcatcga atcgaaaaaa tgggcctttc
    62761 ctttgtctgt tctgcaagaa acgattagcg atgttatcag taaagatacg gatcgtttcg
    62821 gcattggttt atcagaaggg caacaacaag tgatcgactt tatcaaaggc cgtctgcgcc
    62881 aattattgac aacgaagaat attcgtcatg atgtcatcga tgctgttttg aatgcggaac
    62941 aaaaagatct gacaaaagta tttgcagcag cacaattgtt caaacaacat cttgcagatg
    63001 aagacttcaa accttcaatg gaagctttga cacgtgtcgt gaacttagcg aaaaaagcgc
    63061 agcttgaaaa acaatcagaa gtagatcctg agctgttcga aaacgacgca gagaaagaat
    63121 tacacaaagc agtagaagca atgaaagcaa gttttgctga ccaaacgatc cacgaaaact
    63181 acgaccagct tgtcgctctt cgtccactga tcgaaaatta ttttgatcaa acgatggtca
    63241 tggctgatga accagcagta cgtaagaacc gactaacaca acttagtcaa atagctgcca
    63301 tggctttgtc attagcaagc ttggatcaaa tcatcacaaa atagtctttt gtttgaaaaa
    63361 cagagagcat gcacgaaacg tgctgtgtct ctgttttttt gttataaata taaatagctg
    63421 ttattaattc tattttaata atttttgtta ttttattctt tgttcgaatt ttcaaaatgc
    63481 tcatgaaaag agaggaaata aaaatgaaaa cgattaatca tgatcttgtt actgttttat
    63541 ttacttttaa attaggaatt tccctagtca agaaaacttt ttgtggtatg attatatagg
    63601 gaaaacctgt ttataaatat ttctatgaat atattagttt aattatgctt ttaaaataaa
    63661 aagcgctcat tctgatggga atgaatcaca tctttattta tctatcatca atatttagga
    63721 gtgaatctat ggaaaagccg ttcgtcaagt tattggctac tgtggcggta ggcacaggcg
    63781 ctattgtgat ttgcttgttt ggataccatt tcaataatca gcggcaacat catcaacgga
    63841 tcaattacgc agaatctgcc atcaccaatc aaaaagacac cgtgacctct ttatcaaaag
    63901 aagtagataa gctgtacagt acaaaagaaa aaattttcct aaatcctgaa ataacagaag
    63961 aaacagtttc aaatttgtca cataaactat cttctatcaa actttcggca gatgattatg
    64021 acatcaagga atcagaatta cctaaagaag ctgctgcgat ccaagaagaa aagaaagcag
    64081 tcttaacgca gttagaggat gcagaatcaa aactgaagat ccagacagct gtcaacgatt
    64141 tatttactaa aaatgtatca aactggcagc aagctgtaga cgatgtcgtc atcaaagaaa
    64201 aggtgacaag tgcagatgtc gctcgtgtac gtgaaaatat gagctttttt aaagatagtc
    64261 cttggaaaac ggttgttatg caatatctag gattcgctga tacccaaatt gcgcaagtca
    64321 cgcaactaga tcagctattc gatacgatgc tgaaagacgg tcaagtaaca gctactgcta
    64381 cttacgatca atatttgacc gcactcagtc tcatcgaaca gatccggaat gaaaaaataa
    64441 gagccgcata cgcgtcaaaa gcagaaacag tcgctcagca aatgggctat agcaatacga
    64501 gctattaata agcgagaatt caagcaaggc tagcaaacgg aggaaactat ggcaaaacga
    64561 agaagaagat caagagggaa aaagatattt ctaattattt tagcaattct tgtcgtatta
    64621 gtattagcaa tcgtaggagt aggagcaaaa ttatatctag atctctcaca ttctattgaa
    64681 aaaacttacg aatcagtgga acgaacccaa ggagaacgaa caaaaccagt tgatctggac
    64741 aaacaagaat ctttctctgt tctattgatg gggattgata cgggagattt aggtcgggtc
    64801 gatcaaggaa gatcagatac gatgatggtt gccacagtca gtcctgaaga caaacagaca
    64861 acgattgtca gcattcctcg tgatacgtat gtcgacatcg ttggacatga cacaaaagac
    64921 aagatcaacc acgcttacgc attcggcgga gctgccatgg cgatggatac cgtacaaaaa
    64981 tatgtagaca tcccaatcga tcactatgtt tcaatcaata tgaaaggtct aaaagaactc
    65041 gttgatgcag ttggtggtat cgaagtcaat aatgacctca ccttctcaca agatggctat
    65101 gattttacga tcggtaaaat cacattgaac ggggatcagg cattgtctta ttctcgtatg
    65161 cgttatgaag atccaaatgg tgactacggc agacaagaac gtcaaagaaa gatcgtagaa
    65221 ggtgtagcga aaaaagtgtt gagtctgaac ggtgtaagca actatcaatc cgttttgaat
    65281 gctctagagt cgaatatgaa aacagacatg agctttgatg aaatgaaaaa gattgcttta
    65341 gattatcggg atgcatttgg tacgatcaag caagatcagc tgcaaggaga aggcttcatg
    65401 caagacaata tctcatacca aaaagtcagc gatcaagaac ttgatcgtgt gaaaaaagaa
    65461 ttaaaagatc aaatgaatct agagaataaa taggaaagtg gagaaaaaat ggaagagaca
    65521 atcagcttga aagaaatttt tgaaacatta cgcaaacacg tgataacaat cctcatctca
    65581 atgtttgctg gcttggccat ctcaggcatc gtgacgtttt tcatcttgac gccaaaatac
    65641 agctcacaag cccaattgat cgtgacactg ccgcaatcag atactgcaaa tgtcaatgat
    65701 gtcaatacga acctgcaaat gatcaatacg tataaggata tgatcgtcag tgatctagta
    65761 ctaaatgaag tcaaagatcg tttagaaaca gaagacaatg taaaaatgac tgctggacaa
    65821 atcaaagatg ccatctccgt caatcagtca caaaattcac aaatgttctc gatccaagca
    65881 acaagcacaa atgcagtgac ggctcaacaa atcgctaata caacgtcaca agtattccaa
    65941 gagaacgcca aagacgtgat gaatgtcgat aaaatctcga tcatctcagg tgcagttgcc
    66001 aatacgacac ctgtttcgcc aaataataaa ttgaatctag tgattggctt agtgttagga
    66061 atgatggtag gcgtaggtct agctttctta tttgaattac tcgaccggac agtaaaagat
    66121 gaaaaatatg tgacggatac attgggcttc ccgatcttag ggactgtacc agaaatgtca
    66181 gcgaaagaat tgaatgctgg tatccgtaaa aaaggaccag ctccgacaca accaaaagct
    66241 acaaacgata aaacagcgcc atcacgcaga agccgctcaa gagtctagga ggaaagaaaa
    66301 atggcacgaa cacagaaaca aaaagcagcc caaactcatg cagtcagttt ggtcacactc
    66361 acaaacccct cttcaccaat cgctgaacaa tatcgtacga ttcggacgaa tatccagttt
    66421 gcctccgcag ctggtcagca aattaaaacg attgttgtga cttcatcagg acctggagaa
    66481 gggaaatcga ccactgcagc aaacattgcc gttgtttttg ccaaatctgg tcaacgggtg
    66541 ctgctagtcg atgcagactt acgtaagccc gtcatctata aaacgttcaa gttgaacaac
    66601 gcaagcggat taagtaccgt tcttagttca tcaggaagtg tagcagatga gatccaacga
    66661 acaccagtcg agaatttgtc gattctgcca agtggaccta aaccaccaaa tccatcagaa
    66721 ctactaagtt cgccaagaat ggatcagatt ttagcagaag caagacaact atttgatgta
    66781 gtgatcttcg acatgccgcc agtagttgcc gtaacagatg cacagatcat gtcttccaaa
    66841 acggatggca ccttattggt cgtacgtgaa aatatgtcac ggaaagaatc attgactaaa
    66901 gcaaaagaat tgctggatat ggtacaagcg cgagtccttg gtgttgtata caatggggca
    66961 gaacacagca aagatgctgg ctattactac gggaattaag aaataaaaag agaggagaca
    67021 agagaaatga tcgatctaca ttgccatatc ctgccaggaa tcgatgacgg agcagaaaac
    67081 atagatgcca gtatcgccat ggctgaaaaa gcgattcaac aagggatcac acatatttta
    67141 tgcacacccc atcataataa tggaaaatac agcaatgaaa aatcacaagt catttctcta
    67201 gtcgcttcgt tacaagcaga attagagaaa agacaattgc ctttgacgtt attggaagga
    67261 caagaagtac gtattaccgg aacactgatc gaagacatcg accgagatga aattttattt
    67321 acagatttag atgatacata tcttctaatc gaatttccga cactggaagt gccgttatat
    67381 gcagaacagc tcttttttga gttgttacaa ctaggaaaga caccagtgat cgtccatcca
    67441 gaacgcaacg cgcattttcg taaagacccg aatcatatgc tgccattcct agatatggga
    67501 tgcttggccc aactcaccgc accaagttat gtcggtgtat ttggaaaaga catccagaaa
    67561 acagccaaaa tgatggtcaa acataatctt gtgcagatgg ctgcttctga tgcccatggg
    67621 gtctctaagc gcacctttta cttaaaagag tgctataagc agattgccaa ggactttggt
    67681 aaggaaaaag tagtacagat gaaacaagtc gcaaaggatc tgatcaacgg ggatgaaatc
    67741 agttatccag tctatgaaga gataaaaaag aagaagtttg gtttatttta gggggagtgt
    67801 aaggtgtttg tattaacaag aagaagaaaa attgccacat tggttgttgt ggacagtttg
    67861 ttattgatcg ctgcaaatat tgcagcagct aaattcatga agccgtttgt agctatacca
    67921 atggacctta ttttaatctc taccggtttg tcgattggtt tttatttatt ttatggtagt
    67981 ttattcaaag ttttcactcg gatcaatcgc tatacaaatt taagagagat cattgcaatt
    68041 tttggttcac tatctgcaag tgacgtctca agtatcctca tactgctgtt cattaatcgg
    68101 caatacagtt tacggttagt tatctttgct tatctgcttt cgctcttatt gatcatcggt
    68161 agccgattga tctggcgtat ctacatcgaa acaaaaaata tgagatatgt atcagcggat
    68221 tctgctaaaa atacattgat cgttggtgct ggcgaaggcg ggcgtatttt atacaacagc
    68281 tttctgggat ccaaaacggc tcaagatatc caagttgtcg gatttgtaga tgatgatccg
    68341 aataaaagaa atacgtatct ttcaggaaaa aaagtattag gtgcattaaa agatattccg
    68401 gaattgattg aaaaatatga cattcaaatg gtaacgatcg ctatcccttc cttatcaaga
    68461 aaaaaattac gaagaatctt cgagttagtc gaatccgctc acgtgaaagt caacacgatg
    68521 ccttctatag aagaacttgc ttcaggaaaa attagcgtat caaaattaaa aacaattgac
    68581 gtagtggatt tactgggaag agatgaggta aagctggata ttgaatccat caaagatcag
    68641 atcacagaca aagtcattct tgtcaccggc gcaggaggat cgatcggttc agaaatctgt
    68701 cggcaaatca ttcaattcaa tcctgcaaag ctattgcttt taggacatgg ggagaactcg
    68761 atctacttga ttgaccgtga gttacgcacg catcatcaaa attgtcctac agaaatcgta
    68821 ccgatcatcg cagatatcca agatcgcgag aaaatcaatg agatcatgga acaatatcat
    68881 ccagatatcg tctaccatgc agctgctcat aaacatgtac cactgatgga atataatcca
    68941 aaagaagcag tcaaaaacaa tattttcggt acaaaaaatg tagcagaagc agctaaagca
    69001 gcaaaagtga aaaacttcgt catggtatcg acagataaag ctaacaatcc tccaaatgtc
    69061 atgggttcaa caaaacgaat cgctgaaatg atcgtgactg gattgaatga agaaggctgt
    69121 acgaaattct cagctgtcag atttgggaat gtccttggtt ctcgcggtag tgtgattcca
    69181 gtattcagag aacaaattgc taaaggtggt ccaatcactg taacagactt tcgtatgacc
    69241 cgatacttca tgacgattcc tgaagctagt cgtttagtta ttcaatctgg cgcattagca
    69301 aaaggtggcg aaatttttat tctagatatg agtgaaccag tgaagattgt agacctagcc
    69361 aaaaacatga tccgattgag cgggtatagc gaagacgaaa tcgaaatcat tgaaacaggt
    69421 atccgtccag gggaaaaact atatgaagaa ctactgttgg ataaggaaag aaatgatgaa
    69481 gcagtttatg agaaaatctt tgtaggaaac atcaaaggtt actcaataca aaaagtgatg
    69541 gattttgtca agagcctgcc gcaagacgat gaacaattgg ctaaagatat cgtcactttt
    69601 gcaaatgctt cgaataaata ggggggaaat ataaatgaat aaattagaaa aacgtcagat
    69661 accattttca ccgccagata ttactgattt agaaataaaa aacgttgtag aagtattaaa
    69721 atctggatgg ataactacgg gaccaaagac aaaaaaatta gaaaaaaaaa ttacaaagtg
    69781 gttaggaact tctaaagtag tttgtttaaa ttcacaaact gctgctgcag aaacagggtt
    69841 acgtttgctg ggaataggag aaaatgatga ggttatcgtc ccagcttata cttattctgc
    69901 cagtgcatcg gttgtatgcc acataggcgc gaacctagta ttaatagact gtcaacaaga
    69961 ttctttggag atggattacg atgcattaga agcagcaatt acggagaaga caaaagtgat
    70021 tattcctgtt gatcttggtg gtataccttg tgactacgac cgtatttttg agattgtgga
    70081 gaaaaaaaga aatttatttc aacctagtaa tgagattcag aaagcttatg gtcgtataat
    70141 tgttatggca gattctgctc atgcatttgg agctaattgg catgatcaga tggttggtaa
    70201 tgttgctgac ttgacaacat tttcatttca tgctgttaag aattttacaa ctgcagaagg
    70261 tggagcttta gtatggaaag agcacgacaa actagataat gaggcaatgt atcatcagtg
    70321 ccagctgctt tctttgcatg gacagtcaaa agatgcactt actaaaacac agttgggtgc
    70381 atgggaatat gatattgtgg gtccatggta taaatgtaat atgactgatg ttactgcatc
    70441 aattgggttg gcacaatttg aacgctatcc taatattctg aaaagaagaa agaatataat
    70501 taagaggtat gatgaagcct ttcaacaact aggaattgaa gttcttatgc attatacgga
    70561 tgattatagt tcttcaggcc atttatatat tactagagta cctaacatta gttctgagca
    70621 aagaaatgaa ataattataa aaatggcaga acaagggatt gcttgcaacg ttcactataa
    70681 accacttcca atgtttacag catataaaaa tatggggttt gatattaata actatcctaa
    70741 tgcctatgct cattttgtaa atgagattac attaccattg cacacgaaac ttacagatga
    70801 agaagtagaa tacgtaatta ataactatag taagattgta aaggatttgg ttggatgata
    70861 ggagaggcaa aatgagaaag tgggaagatt tgccaaaaga aatgcagaat gatgaaatac
    70921 ggtattatta tgatatcctc agtaaaaaaa aattcagctt agtggtaaaa agagtatttg
    70981 atattttagt gtctgcaact ttgttactga cactttcatg gttatttttt attcttgcaa
    71041 tagtgataaa aattgattct cctggacctg tattttatag acaagaacgt attactcgtt
    71101 atggaaaaaa atttaaaatt tataagtttc gtactatggt aataaatgca gataaagatg
    71161 gcactcttgt tactgtgaaa aatgatgatc gtattacaag agtaggaaag gtaatccgta
    71221 aatatagatt agatgaaatt agtcagctaa ttaacgtttt ggtcggagat atgtcttttg
    71281 taggaaccag accagaagtt ggaaaatatg taaagtcgta ttcaccatta atgttagcca
    71341 cattattatt accagccggg attacatcag aaactagtat tttatacaaa gatgaagata
    71401 aattgttgca tgataaaaat aacatcgaca aaacttatat agaaaaaatt cttcccagta
    71461 aaatgtatta caatttgaaa agtatcagtg aatttagttg tatgaatgat ttgaaaataa
    71521 tgtgtaaaac tatttttgtt atatttggta aagaatatca cgccgactta gaaggtgaac
    71581 gagagtttat taatcagata aaatgaatgg aggataagag ttttggtgat tgaagagata
    71641 aaaagttcgg ataaagagtt aattaattcg attgtcgata ttcatatgag aacatttaca
    71701 aatttttttt tgactttcat gggaaaaaag tttttggaat tgatgtatcg ttcttacaca
    71761 gaatataatg attctggtat attggttgct attcaaaatg ataagccaat aggatttctt
    71821 gcatattctg gagatatgag tggtttatat aagtatatga taaagaaaag aataataccg
    71881 tttggatttt atagttgtgt agcctttata aagaaaccca atatccttat gaggcttttt
    71941 agagcttttc taaaaccaag cgaaacaaaa cgtgatgaaa attatgtgga attagcatcc
    72001 attggagtta atccgaaaga gaaatcgata ggagtaggtt ccatgcttat agataactta
    72061 aagagtagaa ttgatttttc aaaatatgaa tatattgcac tagaaacaga tgcattaaat
    72121 aatgatgttg tgaataattt ttataaaaag aatgagttca ttttagaacg taaatattct
    72181 actaatgaag gaagaattat gaatgaatat cggttttata tggagaagaa ttaattatga
    72241 aattattgta tattttaaat gtagctaata aagtaaataa cttttctaaa gctagtatga
    72301 tggcagctaa acaaacgggt ttagaatttt atatagctgg taactggaaa tacaaatccg
    72361 atgaggaaag aaaagctgat gaagtgaaat atggaataaa aatataccaa gttgattttt
    72421 atagaaaccc actaaattta aaaaatataa aagcttatca tcagattgta gagattataa
    72481 aaaatgaaaa aatagatatt atccattgta atacacctat tggaggtgtt gtcggacgga
    72541 ttgctggtct taaatgtaaa gtcaaaaaag taatttacca ggcacatgga tttcattttt
    72601 attcaggtgc tcctaaaata aattggttta tatattatcc tatggaacgt tggctagctc
    72661 attatacaga tgttttgatt acaataaatc atgaggatta tactttagct caaaaacttc
    72721 gtcttaggaa aggtggaaaa gcttattata ttccaggtgt gggtatagat acaaataggt
    72781 ttatgtcttc cacatcaata aggaatttta gagaaagtat atgtaaagaa cttaatatac
    72841 ctgatacagc aaaaatcatt ttatctgtag gagagctaaa tgagaataaa aaccatttat
    72901 cagtaataca tgcattacaa aaaattccgc tgcatacaga tatctattat attatcgctg
    72961 gggtaggaga aatgagggag acactacaaa atattgctaa tgaattagga ttacatcagc
    73021 gagttttttt actaggatat agaagtgata tacccaaatt attagctgct gcaaacatat
    73081 atattctacc ctcattaagg gaaggcctca acgcctcttt aatggaagcg atggctagtg
    73141 gtttaccatg tattgtcggt aatataagag gaaatgtaga tcttatagaa gatggtaagg
    73201 gtggatttct aatcaatcct aaagacgaag aagaaattgc tggtgcgata aatagattgg
    73261 ctgataacaa attattgtgt gaatctatgg gggcacataa tttagacaag ataaaagatt
    73321 ttgatttatc agttgtgata aaccaaataa ataatgttta ccatgaaatt gtaagtaaat
    73381 aattgaattg aaagtgatat taatatgaaa aaaataaaaa ttatgcattt gttgcaaagt
    73441 aatagatttt ctggcgctga aaatattgtt tgtcaaataa tgagtttatt tcaaaataac
    73501 gaaaaatttg agatgattta cgttagccca gatggtccta tagcaaatat tttaaatatt
    73561 agaggtttaa gttacttacc attaaaaaaa ttttcgagaa aagaaattga cagagccgta
    73621 catgaattaa acccagatat aattcatgct catgatttta atgctagtgt aagagcaagt
    73681 agatataaga agcaaatcat cctttcccat ttgcacaata atcccttgtg gttacctaaa
    73741 ctagacataa gaactattat atattcttta tgttcgtcta ggtttaattc agtaattggt
    73801 gtttcgaatt ccgttaagga agaatttcgt tacaaacaat taataaaaga taaatttgtg
    73861 ttgttaccta acactgtaaa tactgaaaga attataaaaa tggggaatga atttgttgaa
    73921 gatgatattg atattttata tgtaggacgc atggcagaac ctaaaaatcc aataggtgca
    73981 attaatgttt tagaaaatgt agtaaaaaaa tattcaaaac atttacgtgt cgtgatgatt
    74041 ggtgaaggac cattatttga tgaagttaag atgcaaatac aaaaaagaaa cttaacagat
    74101 gttattgagt taaagggatt caaaagtaat ccctataagt acatgaagaa atctaaagtt
    74161 ctattaatgc catctctttg ggaagggttt ggcctagtat cagtagaggc aatgttgtta
    74221 gagacgcctg ttgtagctta taacgtagga ggattgaagg atattatcga tgagacaaat
    74281 ggatttctgt gtggtagtga agttgaatta tctaattcac taatgaagct attaaattca
    74341 gaagaactta gaaaaaaaat gggagaaaat gctgctatta gtgcaaagaa attttctaat
    74401 atgaatcgtt atcaaggagt attagaaaaa atttatgtat ctgcagcttt aaaataaaat
    74461 atgaattata aaaatagaga tcaattagtt ttacgaaaaa taatacccat tagtattttg
    74521 tttcaatcag gaatgatttt ttattcactg atgccctcaa tagcaattgc agttgtttct
    74581 ttttttatgt ttttgtatta tatgtggtgc ttaaaaaagt atttttgttt agcagatagc
    74641 ttattgttaa catcaattct tttcattcca acatcaacta tatctatatt aggaactagt
    74701 tattctagct taccattgac gtggcataat ctaataataa taattttgat gttatatatt
    74761 attatagaag gaacattaaa tcgttcatac ttgattattt tatttttatt tatttgtttt
    74821 ggaatatcga cgtctatgtt cttacctttt ttaatagatg cattaaagca attaatgact
    74881 atttcgttgt ttatctgtag ttttttaata ggaaaacgtt ttaaaatgta tagcaaaaac
    74941 ttaactatga ttgggtggaa tttctatttc ataggagtag tatctatggc gtttcaggta
    75001 tatttgcaac gagtatatat tttatctact ggtgtaataa taggccatta tgcagaaatg
    75061 ggtttaaata gaattgcata tgcaggtttg atgggagatt ttagttttgc agggttatat
    75121 cttgctacag gctgtctata tgcttttcta aaatatgtgg atttaaaaaa ttggaaatta
    75181 ttattcttta taataataga agtattttta ttaggtgcaa ttttatgtgt tagtgcaaga
    75241 acagggttag tttccttgtt tgtcacaatg acattgtatt atctatttaa tataaataga
    75301 attagtgttc ctcatctttt agttctaata ggtggaatca taactacacc ttatatacta
    75361 gtaatgttaa tggcaggtcg ttctggacaa agtcttttgg attcttcagg cagattagaa
    75421 aactatatgt cctctttaaa tgcttttagt gataaatact taataggata tggattagga
    75481 ttaaataatt tatacacgct actaggtgta gcagtaccac ataatttttt tattcaatat
    75541 ttattacaga caggaattat tggtacgcta attattttaa gtggcttctt taaatttacg
    75601 tatgaagaat taaagaaatc aggttgctat aaatggttat ttttgatgat agtagtggga
    75661 gcaatgttta taccggatat tgtatcttcg cgttttcttt acgcaatagt tgttttgtgt
    75721 atgatttctg catcagaaag aactataaaa aaagaaagtt gaggtagaaa aaatgagaag
    75781 aaaagcagag aaatgggcag ataaagcttg tagacaatac aggaatggtc aaaataaaat
    75841 gtcaaaaata tcctgctata ttttaaggat tatttatgga tgtgaattct acggacaggt
    75901 agattttagc tctaatgctc aactagtcca taatggtctt ggttgtgtat tccaccctaa
    75961 aacaaaaatc ggtaataatt gtaaaatata tcaaaatgtg actttgggtg gaaatggcaa
    76021 aataataaat ggaaaagaaa ctgttggggc accaacgcta gaggaaaatg tggctgtttt
    76081 cgctggtgca tgtgttttag gaccaattaa tatcggacat gattcaatca taggtgcaaa
    76141 tgctgtagtt acaaaaagtg ttccaccata tagcttagta tatggaaatc cagcaatcat
    76201 aacagagttg aaatttgatt ataaatttga ttaaaaagta atgtttaata tgcgaaaggt
    76261 tgctatattt atttagcaaa atggggtaat aaatgggaaa taatattcat ggaaagacag
    76321 caaaagcttt aaaatggtca tccttagctg aaataattgc aaagattata actccaattt
    76381 cgaatatgat tttagctaga ttattgactc cagatgcttt tggagtagta gccactgtaa
    76441 ctatggttat tagtttcgct gatatgttta gtgattcagg atttcaaaaa tttttagtac
    76501 agcatgaatt tgataatgaa gaacacatgt tttcatcaac aaatgtagct tttactagta
    76561 acttaggtat ttctttatta ttatggttat ttatttgtgt gtttaataat aaaatagcgc
    76621 acttagttgg aaattctgga cttggattag taattatagt agctggagtt tctcttccaa
    76681 ttacttcttt ttccagtata caatcggcaa tttttagacg aaattttgat tacaaaattt
    76741 tgtgttatgc tagaataata tctgcattga tacctttagt tattacagta ccgttggcga
    76801 taattggact aagttattgg tcactagtaa ttggatctat aataggaaat ttagttacag
    76861 ctgcaatatt aactaagtta tcagagtgga aaccaaaact ttttttttca aaaaaagaat
    76921 tttacgaaat gttttccttt agtgcgtggt cactagtgga atcattaggt acatggttgt
    76981 catcttatat aggtactttt atcgtaggag gcattttaag cgtatactat ttgggaatat
    77041 acaaaactac aatgacaacg gttaatggta tttttgcaat tgtaacttca gcaacaacaa
    77101 ctgtattatt ttcaacatta tctcgtttac aaaatagtaa aacggagtat gataagacat
    77161 atttagattt tattaaaatt gtttccattt ttattattcc tctgggtata ggtatatatg
    77221 tatataggga actagtaaca aatattctac tcgggagtca atggaaagag gctgtaccat
    77281 ttgttgggat atatggatta atgagctgtt ttactcttgt cttgggacaa tatgcctctg
    77341 agtactatcg tggtttagga aaaccaaaag caaatgttct tatgactatc ctacatttag
    77401 cagtattaat tccagttcta ataatctatt caaggaaagg gtttatagaa ctagcatatg
    77461 gtagatcttt cgttaagata gagcagatta tagtcttttg gattatttta tggtttggtt
    77521 ttaagtttaa tccatttaaa attttaaagc aggtttggaa atcttgtgct agtgcattgc
    77581 taatgggagt tctagcaaaa attatgttgg aattctgtac taattatgtt atgcaattac
    77641 tttcagtgtg tctttgtgta attctatatt tttttatata tagttgtata tttaaaggaa
    77701 aaacagaaat aattaatatg gttagaatgt ttactggtaa aggatattaa gagagatttt
    77761 tatggcaagg ttgtgattag gaaaatgaaa aaagtaacaa ttttaattcc tggaatgtat
    77821 tatggtggaa tggaaagagt agcttttata acgcgtcaaa tacttttgaa aaataattat
    77881 aatgtatcat ttgtaactct ttttgataac gatgcagatt atcagccaaa ttttgaatat
    77941 ttatcattaa aatgtgatat aaagccatca aaatttggta aagtaattaa catttttaaa
    78001 agagtttata aaatgaaaag tgtcaaaaaa aaattgaaaa cggatataac tatatctttt
    78061 ggacaaagtt gtaatttagt aaatgtttta tcaaagagag atgataaagt atatgttgga
    78121 atccggtcct atgactggct atttcaatat atattccatt actatgtaga taaatttgta
    78181 tataagaaag cagatgctgt tgtgtctgtc agtcagttaa ttaaacgtga tgctgaaaat
    78241 attttcaatt ttaataagga taaaagctat tttttatata atccatatga tttagagttg
    78301 ataaataata agagtaaaga aaaaattaca gaaatagagg ttccaacaga caaaaaaatt
    78361 atagtgacgg ttggtcgatt agaagatcaa aaaggtttat atcatctaat taaagctata
    78421 tctatgttaa agaacaaaga taatgttgtt gtgtacatct taggacatgg gacaaaaaaa
    78481 gaattattag aaaatttaat aaaagcatat caactacaaa acgtaatatt tttgctaggt
    78541 ggccaatcaa atccttataa atacatgtca cgtgcagatt tatatgtcat gccatctata
    78601 actgaaggtt ttcctaatgc attagttgaa gcaatgtcta cagaaactgc tgtcttatgt
    78661 gcagattgca aatctgggcc aagagaaata ttatcgaata gaacgctaga cacgatttgt
    78721 gaaaatatag aatatgctga atcaggcata ttagtatgtc caatgacaga cagtagaaat
    78781 tattcgcccc aatatgaaga atgtgataaa aatttagcga atgctataga agaattgatt
    78841 gaaaacgata atttgaggaa taagtatgca aaagcagcaa aaaagagagc agaactatat
    78901 agttatgatg cctttgaaca taacttgttg caaattatga agacatttaa ttaattcata
    78961 tgatgaaata aaaataaggg agtataacta gatgctgaaa aaaaatacat ctttacagaa
    79021 taaaacaata ttaataactg gcgcagccgg ttttattgga tcaaatttgg ttcttgagtt
    79081 attacgtact cagtcatcaa taaaaatcat tggcattgac aatatgaatg attactatga
    79141 tgtctctatt aagaactata gattatcaga gatagaaacg gaggcaaaga accatccagg
    79201 atctacttgg aattttatca aaggttctat tgctgataaa gcaacaattg atttcctctt
    79261 tgataattat aaaccaagta tcgtggtgaa tttagcagct caggcaggag tccgttattc
    79321 aattactaat ccagatatgt atatcgaatc taacataata ggattctata atattcttga
    79381 agcttgtcgt cattcatatg ataatggaga atctggtgtg gaacatttag tgtatgcctc
    79441 atcgtcttcc gtttatggta ctaataagaa aattccttat tctacagagg ataaagtaga
    79501 caatcaagta tcgttgtatg cagcaactaa gaaaagtaat gaatcaatgg cacatgcata
    79561 ttctaaactt tacaatattc cgtctacagg gctacgtttc tttacagtat atggtcctgc
    79621 tggtcgtcca gatatggctt attttggttt tactgataaa cttcgtgctg gtgataatat
    79681 ccaaatattc aattatggga attgcaagcg tgactttacc tatatagatg atattgttga
    79741 aggagtaaag agggttatgc agtgcgctcc agagaaaatt gatggggaag atgggctacc
    79801 aatcccacca tatcatattt ataatattgg taacaatacg ccggaaaacc tactagattt
    79861 tgtagatatt ctacaacaag agctaattgc agcaggggtg ctaccagaag attacgactt
    79921 tgaatctcat accgaactag ttccaatgca accaggagat gtgccagtta cttatgcaga
    79981 tactagtgcg ttagaacgag attttgaatt taaaccaagt acaagtttgc gtgacgggct
    80041 tcgtaaattt gcgcagtggt ataagtcttt ttatgaagta taattgtatt tttttactta
    80101 taaaagttta tagaaacacc tcagacacta caaatctgag gtgttatttt ttaatctcgt
    80161 tgaaataaat ctctggtata tactttttct tttacatcat caagattact atcgtaacga
    80221 ttagcaataa tactgtgact gatattttta aaatcatcta aattatttat tacttttgaa
    80281 ccaaaaaatg tagtgttatt ttcaagtgtt ggttcataaa ttacaatagt tgcccccttt
    80341 gctttaattc gcttcataac tccttgaata gatgactgac ggaagttgtc tgaattactc
    80401 ttcattgtaa gacggtatac acctatgact acctcttttt ctttttctgc attccacgaa
    80461 ctgttagcct catacgtgcc agcaagttct aacactcgat ctgctataaa gtcttttctt
    80521 gtacgattac tatcgacaat tgcacttatc atattctgag gaacatcgtt atagttagtg
    80581 agaagttgtt ttgtatcttt cggtaaacaa tagcctccat atccaaaaga tggattatta
    80641 taatgtgtgc caattcttgg atctaagcaa accccgtgaa tgatttcttg tgtatttagt
    80701 cctttcattt ctgcataagt atccagctca ttgaagtaag atactcgaag tgcaaggtaa
    80761 gtattagcga ataatttaac tgcttcagct tctgtgaatc ccatgaaaag agtttcgata
    80821 tcttttttga ttgctccttc ttggagtaaa tctgcaaaag tgtgagaggc ttctcgtaaa
    80881 gttttgtcag tttggtccgt gccgacaata attcgcgaag gatatagatt gtcatataat
    80941 gccttagatt ctctgagaaa ttctgggctg aatagaatat ttttagtatt gtatttttta
    81001 cgaatacttt cggtatagcc tacgggtacc gtcgacttga tgaccattat tgcctttgga
    81061 ttgacttcta acaccaattt gattactgac tctacagcag aagtatcaaa ataattttgt
    81121 ttactatcat aatttgttgg agcagcaatg acaacaaaat cggcttctct ataggcggct
    81181 gcaccatcag tcgttgcaat taaattaaga tttttttcag ctagatattt ttcaatgtaa
    81241 tcgtcttgta ttggagattt cttattgtta atttgtttta ctttttcagg aagaatgtct
    81301 actgctgtta cctgattgtg ctgggcaaga agagtagcaa tggaaagacc tacgtaacca
    81361 gtaccggcta cagcaatatt cttcgactga tgttttgttc tgtttgattt atttgattca
    81421 tttataaata gatctgttgg ttcaaaattt agaacttctg ctaatgattc taattgttgt
    81481 attgacggga taaaatcgag agattctact cgactaatta aggcacggtt gataccagta
    81541 gctactgcaa gttgttgttg tgtcattttc agagattttc tagaatcaat aatgatttga
    81601 gctaaacgtt tttgagataa ctttttcatg atgcactcct ttttttgttg ctaataataa
    81661 caaacaattt tttcttctat aacagaatag cttattatta ataaaactgt caattttttt
    81721 attgattaaa aagatatttt ttgattttaa gtattttcaa ttattttttg ttacttaaaa
    81781 taactttata gattgtgaat aactttatac ataaaaagtt tacgtgagtc catacaatat
    81841 aaagaataaa aaatgtgatg ttttaaactg taaccaacca taataaactg cttctcaatt
    81901 ctccctcata cgcaatacat aggcgtcaag caggattctc gcgatgatct ggagaggcaa
    81961 gcgtgaacgt acttcataat cagggaaata agaaccttct gatttgaaac ctacgagatt
    82021 tatctcgcaa taatctttga gtgtagagga atgattggct gtaactagaa tcgaaccaat
    82081 ctctgcatca tagcagttct ttgcggcggt gacgagttct tttgtctcgc cgttcaaaga
    82141 aacaaaaata acgctgtctt tcttagttag tttccgactg atgcttttga taatctctgg
    82201 atcagtatgc atttgacaat tttttcctgt taattgaagt tttacgagca tctcttgacc
    82261 aatcatttct gaaaatcctc gggcaaagac aaaaacccgg tcagtaaatt tgattctttg
    82321 tattgcatct tcaatgttcc cgatttccaa catattgatc gtacgtacca cttcttgttc
    82381 attttttaga atggctcgac ggataccttt gtctacttta tctaaaaaga aaaattgatg
    82441 ttcttgtttt ctccttcttt tagatggtgc ttaaacgaag taaatccttc atagcctttt
    82501 ttcttcattg tccgcacaat ggtggctgtt gagacatttg cttgttcact tagtttcacg
    82561 atggagtagt tagggatctc taggatgtgg tgttcgataa agttccagag gtactgttct
    82621 gtttcactta atttgtgatc catattcttt ccttctttca ctaaaagtta gttaaaaaat
    82681 agcacgatgt gtttataaat gtaaaggttt tctttgtgtt ggaacgatta agaaaacatt
    82741 ttctctttcg cgtatttcat aatagattca aggaggtcat tggttatgtc tatctacaca
    82801 tgcacgatga atttggcaat tgatctattt attgaaacag aggagatgca tccttttatg
    82861 gtaaaccgta caaaggagga tgacattcag gcaaacggaa aaggagtaaa tgtgtcacta
    82921 gtattaaaga tgctagattt cccaagtacg gcattaggtt tttctgctgg tttcacagga
    82981 aaatatatag aagactattt acagaagaaa caaatccaaa cagagtttat tgaagtgcct
    83041 ggtatgacgc gtatcaatgt atttacacaa gtcaatcaaa cgagagaaga atacaaatta
    83101 gtgaatcaag gacctgaaat accgcaggca gctgtccata attttttaaa tcaaataaga
    83161 gcattacaag cagaggatta tctttgtgtt tctgggagtt taccaagagg aatgtctccg
    83221 aaggttttag tggaaatcag tcggatttgt caggaaaagg agattcattt gattattgat
    83281 agcagtgatc aagaggtcat ggattgtttg ccctatcgac catttttgct gaaaccgaat
    83341 gaggaagaac tttcttcttg gttcggacga aaaatggtta cagatgaaga ttactttgtt
    83401 tatggacaac gactggtaga gtcaggtgca gaaaatgttt tgttatccct tggtgagaaa
    83461 ggagcgattc tttttacgaa agacagggtg attcgaggaa actcgccaaa aggaaaagtt
    83521 gtcaatacag catgtgcagg tgatgccatg ttaggcactt ttttagtagg atacatgaat
    83581 cgacgaccgc ttgatgaaac gttacgtaaa agcatagcag caggcagctc tactgctttt
    83641 cgtaaaggac tgactgattt tttggatgtg gaggaattaa gtaaacaaat caaaatcaag
    83701 gaagagaggt tcgaaagatg ggaaaatatc aactaattgc agcaaccggt tgtccgacag
    83761 gaattgcaca cacctacatg gcgcaagagg cattagagca agcagctaga aaaaaaggca
    83821 tcacgatcaa agtggagacc catggacaaa ttgggatcga gaatgaatta acggctgaag
    83881 aaatcaaaca ggcagatgct gtcattattg ccgcagacaa agatgtccat tcagaaagat
    83941 ttgcgggaaa acgagtcatt gatgtttctg tcagtacagg aatcaaggat gcacaacggc
    84001 tgattgacga agcattggca ggaaaaggga ccatcttagc agataatgaa gctgttgata
    84061 ctttagaatc agaaacgata agtggtgcta attttggtcg cagcatctat aaaaatttaa
    84121 tgaatggcgt ctctcatatg ttgcctttcg tggtagctgg cggagtattg attgctattt
    84181 catttgccgt ttggggaatc tattcttttg atccagacca tgcacaatac aatgctacag
    84241 cggcgatgtt aaaaacggtt ggcgatgcag caatggggat gatggttcca gttttagcag
    84301 cttatattgc agaagggatc gcgaaacgtc cagggttagt cgttggattt gttggtggaa
    84361 tcgtggccat gagtggcggt actggatttt tagtaggtat tttagctggg ttcttagcag
    84421 gttattttat cttatttttg caaaagctac tgacaatttt acctaaacaa ctagatggct
    84481 tgaaggcaat cttcttatat ccagttattg gtgtagtgtt tatcggcatc gtgatgtctt
    84541 tgctggcggg tccaatgaag gctataaatg aaggaatgat gagcttttta gctggatttg
    84601 aacattcgaa tccacttgtt cttggcgtga ttgttggttg catgtgtgcg tttgatatgg
    84661 gaggaccgat taataaggcg gcatatgtaa caggtacagc tcttttggca caaggaaaca
    84721 cgacttttat ggctggcgtg tcagtagctt gcattgcacc accgttgatt actggttttg
    84781 caactttatt gtttggtaaa tattttgata ctaatgatcg taatgcaggt ttggttaatt
    84841 ttattttagg atcaactcat attacggagg gagctattcc gtttgctgcg aaagacccga
    84901 tccgagtatt accaacgatg atgttaggct catcaattgc tgctgtcttg acctatctgt
    84961 ttggtgtcca agtaccagcc ccacatggcg gttttttagt gttacctgta gtgacgggaa
    85021 aaatccaatg ggttacagcg attcttattg gttcgatcgt tggtggagtg atactaggtt
    85081 tgatccaaaa gaaaagagta actgataaag acaagaagat ggataataaa gcagcaaatc
    85141 gtacagttat cgaagaagga agagcaggag gcttatcatg acaatcattc atgaagagaa
    85201 cattttttta caacagccat tagatagtca agaagaagca tttaagtttt tagcaaagca
    85261 aacattctgt ttaggaatcg ctcatgacga aaaagaagta tatcgaaaac ttctagaaag
    85321 agaaaaagaa ggtactacag gaataatgtc aggttttgct atccctcatg cgaagtctca
    85381 aacaatcaac gaacctagta tgattatcgt cacactgaac aaaggaattg aatggaacag
    85441 tttagataga cagtcagttg attttatttt tgcgttattt attccagatt cagaagcagg
    85501 aacgactcat ttgaaattat tgtctctcgt tgcacgatca ttgatgcgaa aagaggttac
    85561 agaacagttg agaaaagcaa aatcaaaaac agaaatagcc acaatattaa ctaaagaaat
    85621 aggtgaagat ctatgaagaa gatgagtata gaaaagcagg aacgtttgaa gcgattgacg
    85681 gatgaagctg gaattattag cgcgttagca atcgaccagc gtggtgcttt gaagaaaatg
    85741 atcaaccaat ataaagaagc tacatcagaa gacatcatcc aatttaaaca gatggtttct
    85801 caatacctga ctccctatgc ctcagctatt ttacttgatc cagaatgcgg cctgcctgca
    85861 gcagcgctta gagagaaaga atgtggcttg ctgctagctt atgaaaaaac cggctatgat
    85921 acgaaaatgc cgggaagatt acctgattta ttgaatattt ggtcggtgaa aaggttaaaa
    85981 gaagctggtg cggatgcttg taaattttta ttgtactatg acgtggatga accagcagag
    86041 attaatgtgc aaaaacaaat agttatagaa cggattggtt cagaatgcga tgcagaaggc
    86101 atacctttct ttttagagat cctttcttat gatgcaacta ttggcgatcc gtcctctctt
    86161 gcctatgcaa aagtaaaacc ccataaagtt attgaagcca tgcgagaatt ttcaaaagaa
    86221 cgttatcaag tggatgtatt gaaagtagaa gtgccagtga atatgagatt tgtggaagga
    86281 tatgggcaag agacttgtta tagtcaagca gaggcatccg cgtatttcta tgaacaatcg
    86341 aaagtgactg aacaaccgtt tattttttta agtgcgggag tcaatgctac gttatttcaa
    86401 gatacattac gttttgcaaa acaatcaggt tcgacattca atggtgtctt atgtgggcga
    86461 gcaacatggg cgaagggagt ggcacctttt gttaccgaag gcgaagaaaa agcgagtagt
    86521 tggatgttag aagaaggaaa acaaaatatt aaggaattaa gtacactatt aaaagaaaca
    86581 gcaacacctg tctacgttga tagataagaa aaagttgttt cttcataaaa agatgctgct
    86641 gcaattagat agcgatcaat cgatgattca aattatacat tcacttaaat aaaaatatcg
    86701 actagatttc tttttcaaaa atcttggtcg atatttttaa ttgctaaaac tgttaatgaa
    86761 tttttattac actcttattt actatctact tccgcttctg ctgctttcct gcgttgcggc
    86821 ctttgttatt tgtactgttt tttggttgtt tgatttgttt tgttgcttgt ttgttgtcag
    86881 ctggttttgc tgattctgtc acgtcttttc ttggagtgac gacttgtttt ggcgggtttt
    86941 gtttcaactc ttctgccact tgtgctttca agcgtggttt catcataacg tttgtgatga
    87001 atgtttgcag acagctgaac acaccaccga ctacccagta aagtgtaacg ccggctggcg
    87061 cactgatcga catgaagacg atcatagcag gagagacgat cagcatcgta cgcatcgtct
    87121 ttttctgttc ttcaggaata ccgattgttg aaatatatcc ttgaagcaga taagcgaccc
    87181 ctgcaatggc cacaagcacc atacttggtg agcctagatc gatgccgtaa aaagatgatt
    87241 cacggatacc ttctgtgtag cgagccgtaa aatacaaggc agagaagatc ggcatttgga
    87301 tcaatagagg cagacagccg attccgccgg tcatactcaa tccgttttcg cgatatactt
    87361 gctgcatttc tgcttgtgct gccatttgtt cttcacgtgt tgttgcagct tttagctttt
    87421 gttgtgctgc ttcaacttgt ggttttaacg cttgcatttt ttcagattgg atcattgttt
    87481 ttttcgattg actgatacct agtggcaaga tgatgatacg aacgatcaca gtcattgcaa
    87541 taactgccca gccgtaagac caattgaaat tctcaactag atatgtaatc gcttggccca
    87601 taggatggac gagtactcga taaacgattc ctgaagtgtc agggtttccg tttgaatcca
    87661 tccgcacaca gccagataaa aagagcagga tactgacaag tccggatccc aataaccagt
    87721 ttttccattt attcatagaa tacttcctct tctataattt ttacacaaac ttaactatac
    87781 taaaaaagcg catggaattc aatcaacttc atagaaattt catataaata ttctttcttt
    87841 ttcgtagcga aaaattttga aaaaagacaa aaaatcaaga aagaaatact tggaaagaaa
    87901 agagtgattc caagtgtttc tttcttatat aaaaaactaa aaactttttt gttctgtctg
    87961 gaaaatatgg gttaagcaaa tttattgcaa gttatagatc agctttttta ctacctatct
    88021 ttaatacttg aggcaaagcg cctcaaaaac aacctgatcg acggtgttca aaagtcagtt
    88081 tctcggtatt aagtcaaatt tatgcaaaaa tgtggaaagc cattttcaca aaattttcct
    88141 taatactcaa aactaagcga ccttttcaca accttatccc accacatcaa atttctttcg
    88201 ttcctcaatc atcggatctt cttggacatc cacatactgc actcgtccac ttgggctcgg
    88261 agacttcttg acttcttcga taaatttttg gatgatgtcg tcatttccga ttgcttcgat
    88321 tgtgactgag ccgtcgtctt cgttttttac cgttccggtc acgcctaact gatcagcaac
    88381 catcttggtc atatagcgaa atcccacgcc ctggacacgt ccttggacat tcattttaac
    88441 tttgcgcatg ttcgtcacct ttctttcctg ttttataaat caatgatacc gattttttta
    88501 ggatgaaaca agctcaagca cctattccat gatataatca ggtgaggtga aggaatgtga
    88561 aagagatcca atcagcaaaa aatccaaaaa tcaaagaatt aaaaaagcta cataaaaaga
    88621 aatacagaga agaaaaggca gaatatcttt tggaagggtt ccatctgatc gaagaagctg
    88681 cgtcgtctga tgcagaaata aaagaacttt ttgtgacaca gagaggtatg aaagaatggg
    88741 gagactggct ggctgtaaac aaagagattt ctacttttct agtttcagat gaggtcatga
    88801 ccgctatgtc agatctacct acaccgcaag ggatcttagc ggtgatgacg ttaacatctg
    88861 aagatacgcc agatttttca ggaggctggc ttttactaga taatgtacag gatcctggaa
    88921 atgtgggaac gatgatccgt acggcagatg cgtttggtat ggctggtgtt ttattaggta
    88981 aaggaacggc agatatttat agtacaaagg tgctgcgaag catgcaggga agcaattatc
    89041 atttgcctgt gttacaaaaa gatttggcag aagtgatccc tgtaatgaaa ggcaaagggt
    89101 ttacggtgta cggtacagaa ttaaatgaag aagcacatgc attagacaaa gtagaaaaaa
    89161 cagaggattt cgctataatc atgggaaacg aaggtcaggg agtaagtcag gaaatcttgt
    89221 ctttgactga tcagaacgta tatatcccaa tgaaaggaaa tgcggaatca ttgaatgtcg
    89281 gagtcgcagc agggatcgtt ctttatcatt tttctttatg attaaggaac tattaagctt
    89341 tagctatttt atctagagcg actagaataa tccgaacact ggtggtatac ttagatcaat
    89401 ttcagaagaa aatgaaattc aaaaaggtgg cagatcgata attatgacag aaaaatggcg
    89461 tgaagacgaa gaatatatgt cttatgtaca agatctttta gaaacagaag cagtgaaaaa
    89521 attagcgaat tacacacagc atgttcattc cactcgtttg gagcattcca tcagtgtttc
    89581 ttactatagt tatctgctcg caaaaaaatg gggtggcaat gctaaagcaa cagcgcgtgc
    89641 tggacttttg catgatctgt tctactatga ttggcgtacg acgaaatttg acgaggggac
    89701 acatgcgtat atccatccaa gaattgctgt aaagaatgca gaaaaaatca ccgatttgtc
    89761 ggatcttgag cgagatatca ttttgaagca catgtggggt gcaacgatcg caccgcctaa
    89821 gtataaagaa ggatatattg tgacattcgt ggacaaatac tgcgcagtca aagaagcggc
    89881 tcagcccatg tctgcaagta tgcgtaagag atggcaacgt tactttggga aagaatcctc
    89941 gatttaacag gtaaaaccaa taatagacca tattgaggtt gtgacagaag tggtcagctt
    90001 caagaaataa gaaggaattt acgaaaatta cttctcaaat ttttgtgaag tttcggctta
    90061 ttaccgcaga tgcaagcttt tgaacaccat tcattcgaaa caagggactt tgacacgact
    90121 tttgtcacag tccttttttc tgtttgcagt tgactatctg ttcaagatac ggtttacttt
    90181 tatttatcga atgaatcatg tacatagaag aataagcatt aaagggggtg atgataagat
    90241 gcaaaacgta tcttatttaa aagagtccgg gatcttcagg taacacatac tttgcagaag
    90301 atcacttttt tctacaaagt atgcactttg gttagaagaa aggactttaa aatcatggaa
    90361 caaacaataa aaccatacca atattttttt ataaaaagag aagtagaaca gttattaaat
    90421 gcgtactcat ctgtcaatga tccaaaaacg gtacaaacag ttcaggcact agcaactgaa
    90481 aagattcgag acatattaga acacgaactg ccagaaatcg atacattttt aacgacagtt
    90541 ttagacgtaa aactgacaaa agcgcaagca gaacgagcat tggaggagct gaagcaaatc
    90601 gttcagccgt ttatgcagcc tagcaaacca caaatcgaga aattattccg aaaagtgaaa
    90661 aaactcaaac aaccagcttg gaatgaaatc gacttgcaag aacatacgta catcggctgg
    90721 aatgatccag gtacgcagaa aaaattcatg atctattacg aagatgaaaa attaaaaggg
    90781 attagtggta ctttatcacc aacgataaat aagggaatct gtgcaatctg tcagaaaaca
    90841 tcgaatgttt cgctttttct ttctacaacg aaagcaggtt ctgatggcac gtatacgaaa
    90901 aaggggaatt atatttgtca tgatagtgac caatgtaatc aacagttaac gaaattggct
    90961 cctttctatg aatttgctga acgtgtaaag aaagaacgat aattttattg ttttttacag
    91021 aaaaatatgc tatcttttaa tggaagtgaa taggtgatgg tgttcgcctt taaatgctaa
    91081 cgaaagatag ctaatgacgc ctactaaagt ctggggacag cccctttctt tagtaggcgt
    91141 ttttttattg aggaggaatt ttttatggaa aaacaattac cgagtccagt acgcatttta
    91201 gtgtacatgc tgaagtggct ggtgatcaca gcgattctcg gtatattcat ggggagcttg
    91261 tctgcttttt tcttaaatag cctgacagtt gtgacagata tccgactatc acatccttgg
    91321 ctcctttatc tactaccagt tagtggtgcg ctttttgctt atctctatgc gtatcacggc
    91381 ggtctttcta gtcgtggaaa caacttagtg atcgatcaag gaaatggtgg agaagaaaaa
    91441 atcccgttgc gacttattcc acttacactg tttggaacca taactaccca tttatttggg
    91501 ggatctgttg gccgtgaagg aacagcagtc caaatggggg gagcgttagc agataataca
    91561 gcacgtttgt tccgattgga taaatcagaa cgggaaatct tgattatcag tggaatcagt
    91621 gcgggtttta gttctgtatt tggcacacct ttagctggaa cattatttgg attagaagtg
    91681 ttggcaatcg ggaaagtccg aacagaagcg atcttcccta gcttctttgc tgcactgttt
    91741 gcaaatttca tgacagaaag ctatggtgtt tctcatctac attaccaaat gggtgtgatt
    91801 cctgaatgga gtatgttgct gttcttcaaa gtttttgttg ctgggattgc ttttggtttg
    91861 attggttggg tattcagccg ttcgatcgtc tttttaaaag cgcgatatgc acaatggatt
    91921 cctcatcctg tttggcgaaa tacgataggt ggagctgtag ttgtggcagc agcattgatt
    91981 ttgcaaacac aacgttatct cggattgagt cttccgttac ttcaagaatc atttaatgga
    92041 caggcacatg tctatgattt tattgggaag ttattcttca cagttttgtc tttaggcgcg
    92101 ggatatcaag ggggagaagt gacaccattg tttgaaattg gtgcaacgct tggtgcagca
    92161 ctagcgcctt tgctccatgt ttctgttcct tttcttgcag gattgggctt tatcggagta
    92221 ttttctggtg cgacaaatac accgattgcc tgctttgtga tggggatcga attgttcggt
    92281 tcacaagcgg cagtatactt ctttatgatc tgcttgatca gctttatgtg ttcaggcaac
    92341 agcggtattt attctgctca gcaagtagcg gtcaaaaaag ggatactctt tttgccaata
    92401 gttaagagaa tgaaagaaaa aaacaaggtg tgacatatgt tttgtcacac cttgtttttt
    92461 tagaaaagta aagtaatcag cgataagaat gcggagcctg cgaaaagcaa tccgcaaatg
    92521 atcatatgtc tttttttgtt catcatcaag atggcgatgt attctcttaa aaacgcatta
    92581 ggcaagtagt agaaagctgt ttttgcacca ataccatttg ctttcaattt ggcttgccac
    92641 gcataaagac cggctctaaa aatgtggtaa ttgttggaac taaagatcgc gcggtatggc
    92701 cctttcattt gctgatccat gatttccttt gaatagagca tgttctccaa agtggttgtc
    92761 gaattggttt cgacaagaat gtctctttca gggattcctt gttccatggc atattgtttc
    92821 atcgcaatgg cctctggtac tttttcgtct gctccttgcc cgccagacat caataagatg
    92881 ggcggattta atgtagcacg gctttgagcc cgataaaaag caattgcctt attgattcgc
    92941 ttggctagaa gaggagaaac tgtttctcca ttgatcaacc cagcgcctaa cacaacgatg
    93001 aagtcttgat tgtatcgagg ccggttgaac tgatacaaga atgagacagt caaaaagttg
    93061 tagaatacga taaatagata gatcaagatc aggggaacgc agaaaaacaa agcatttatc
    93121 cattgcggca aatattttaa caagaaaaag tcaaaaacaa gaaacagtgt aagaaaaatg
    93181 gctagtatca acgttaaaag attagctaat gaatgcgatt ctctacgtaa aactgtgacc
    93241 ccgttccaaa aaagaaaaac aatcaatcca taaataccaa ataaaaggac aagtagcaat
    93301 ggaatcgtga tcaaggcgat cagtccgcca aggaaaatat tttgcgtttc atacagcaag
    93361 acaaacaagt agatgccgaa actgatgagg aaaacattga ataaaagacc attcagcagc
    93421 cttcgttttt ctgtgaaata agaaaaagca aagatactaa agaacaacaa tggaatcaaa
    93481 aaataaaagg tcgaataaaa aatttccaac acgacaaaat aagttaagat taccgtaaat
    93541 gtccacgtac tgccgtaaaa gaacaaggaa ggatccttct tctgttttcg ccaataaacg
    93601 atagagaata ccccaataag atagagaact aaaaagatca gatctctggt tagattcata
    93661 aattcaactc ctttttctta tacagtataa cgaaaataga tgaaaaaagc tgttatttaa
    93721 actagaaaaa gcaaaaaaac atctttccga tggaaagatg tttttcttat tgttcaatta
    93781 aaacaagttg ccgaaaaatt ctgcgacgcg tcgccagcca atcacgaata tattcgcttt
    93841 ttccactgtt ttatccgtaa tgatctctgt tgaaggtgca ttgttgtctt ctaaatagcc
    93901 taatttatcg tctgccaagg tgatcgtagc ggtaccgatt tttgtacctt tatccatagg
    93961 tgcttggatc tcattgtcag tgacttgctt cttgtcaagt gttggcgtga tcgttaattt
    94021 gccagtatcc atatcgtttc gtacccatac ttttacaggg cttttaagca caacaggaac
    94081 tgttgattct tttccgtctt ttacatcaat ggtttttaga ctaggaatac ttgcgttagc
    94141 ttttcctagc tctttttctg accaattgtc atagcagtag tccatcaaac ggtctgtttc
    94201 attgaagcgg gcactcgggt tttccgcatg gccgtccgca ttcaatacga cagtgatgat
    94261 ccgttgatcg tttttagtga tcgtaccaac gaaacaagca cctgcaagct cagtcgtacc
    94321 agtttttaat ccgtccacgc cttccttgta attaacgaat cctgggagca tccagttcca
    94381 gttgaccatt tccactggtg attgcgtatt ttcgccaaac atttgggtcg tagtacttga
    94441 tacatccagt atttctggga aatccaagat caaatggcgg gcaacgatgg ccacatcttg
    94501 agcagacatt tgattttcgt cgttttctcc agtgccttct ggtcggtttt cgccaagata
    94561 agagttgttc aatcctgatg cattaacgat tgttgcatct ttgattcccc aatctttcaa
    94621 ttgttctttc attcgttcag tgaatttagc ttcgctgcca gagatttttt ctgccaaggc
    94681 caccattgaa gcattggctg actggatgat tgcagagtcg aataattctt tgacagtgta
    94741 ggtgttttct ttatgcaaag gaacattcga taaatctggg gtgatactca aattttctgc
    94801 ataatctgaa atcgaaactt tatcatccca tgacagtttt ccttctttta cttgatcaag
    94861 gacgatgtaa agaccgatga tttttgtgat tgaagcgatc cccatggttt tttctccatc
    94921 ttgatcataa agaatcttac cgctttgcgc atctacagca aaagctgctt ttgcatttac
    94981 tttgaacgta tcttcagctt gcacagcaac agctggtaga aaagaagcaa ggcaaagaat
    95041 gagactagcc aataatagga ctagacgtgt tttttttatg gacatatccg atctccttgt
    95101 aattaatttg tttcgctaca aattaaaatt ttatcagaga ggggagagag tttcaatgtt
    95161 tctgaaaaaa ctttaggata agaacgcgcg ttatggaagt ttagcggtcg tttttacgta
    95221 cttttacagg aataggctgt gtttccgcat ctaataagcg ggaagcgctg aaagcaaata
    95281 aactgataat acttaataaa ctgaaaatca taatcaaatg cataagatcc acctctttta
    95341 ttctttttct tagtttatca gcatttcatg aagaatagtt gaagactggg gctaaataat
    95401 tgaggaaatt atgaagataa cttaaaaaaa tagctaaatt taaaaccgta gaaaccgttt
    95461 tattttttta gatacgtttt attgtatgga aaaatagtgt tgtggtagac tttagataga
    95521 aacaaaggaa tgattttttt aggaggggta cgtttatggc aaaaaaggat aaagaattat
    95581 tgacacaatt gacttcagaa ggcgctaaag gaccattcgt cacgatcatg ctgaatacgc
    95641 atgtcgccca tcaagatgtg gaaaaagatc agatcaaatt caaaaatttt gcgaaagaag
    95701 caaagaaacg ttttgagaaa aaatattccg aacatgactg gtccccgttc caagaaaaaa
    95761 ttgaaaattt gttaggagat ccttcgtttt ggcgtagtgc aactacgagt gtagcggtca
    95821 ttataactgc tgaccagacc tatatccatc gtttgagtat cccggtagac gatcaatact
    95881 atgtaagtga tcttccttat ttactggcta ttatcaaaaa tgggcagttc aactattctt
    95941 attatttatt gggattgaac cgcgactcca tgaaattgta tgaggtcagc aacaaacaag
    96001 taaaagaagt atctctacca gaaggggcac cggttgatgt cgttactgca ttgggatctg
    96061 aactgacagg tggcggtttg aacttctctt ctaatggagg aggcggagcc cgagatggag
    96121 taactttcca tggcgtaaat ccaaaagatg aagaagtaga gatcgattgg gtcaactatt
    96181 accaagctgt tgatacgtac ttgaaggatt ctttcgaaaa tcctgaacaa tggccgattt
    96241 atttatttgc attaccagaa aatcagacga tgttcaaaaa aattgctaaa aatccctatt
    96301 attgtgcaga cgttgcgatt tctgcttctc ctgcgcagct atcctttaga gatatcgaag
    96361 aaggggcgaa gaagctgtca agtgaactcg cagctcaaga atcaaaagaa tacaataaac
    96421 tcttagataa gaaattcatc gatcagttag ttgatatcgt tccagctgcg aaagaaggaa
    96481 aagtgtcaca tttatttatc gctacgtcaa acttagctga tggtttcggt gaagatcctg
    96541 aaacagaata tgatcggcgt caagtgttga atgcattagc agatgatgtg atcattaatg
    96601 gcgggaaagt gtttattttg gatcaaaaag atgcgccaga tgaaaagagt ctgacagcga
    96661 ttcttcgtta ttaaaagagg ttgtgaaatc agtgttttga cctgagtatt agagaaacaa
    96721 acggaaaaat agtttcacat atttttccgt tttttgagct aataccgcag atgcaagctt
    96781 ttgaacaccg tttaaggaag aggttgtgac agaagtggtc agcttcaaga aataagaaga
    96841 gattgacaaa aattatttct caaatttttg tgaaatttcg acttatttcc gaagaagcta
    96901 cttctggaac accgtttaaa aaagaggttg tgacgtggtc acgacctctt tttgacgatt
    96961 atgatacaaa aaacatcatt tatgaacaaa atgtgaataa cgggcgttct tgagatatga
    97021 ttttaattgg gaaaaactta tcgataagga ggtctttatg aaaaaaagac tgttatggtg
    97081 tttgctgttt ctatccctaa gtttaacaag tcagccagtt tttgctgaag aaacacagcg
    97141 gtctcctatt acaggcacac gtctgtacaa aaatgtttat gtacagacaa cagatcttga
    97201 ttctgcgatt cctgaaacag aagaacggtc tttgcagcca agatttggtt acttttggta
    97261 ctgtccgacc tgtgattatg aaagttgctg gcatttctta cattctacag ctgcagcttt
    97321 tgcttttact catactcaga aatatgatgg acatcatcct gttatttatg aggtatagat
    97381 atgagcaaaa aagaaaaact aatctcgttg atcgtattgg tttgccttgt tcttctggta
    97441 actgtcatag gctatcagaa ataccatgag aacatcagac ctactaaaga atcttcccca
    97501 gcctcgaccg ttgaaacaga accgataagt agtcagaaag aataattttt ttagtttaaa
    97561 gaagaacatc agagcaaaaa aacaccaact gaacaatatg tcgtttattt taaaaaaagt
    97621 tcggtttttc actttatgta atcgctgaga aaactttttt taataaaaaa agtcgaaaaa
    97681 ctctagcttt tttgtaaacg gtatgatata ctataggagt agtttttgtt cggtaatctg
    97741 tggtagcttg tttcaaataa acatcttcca gatatacacc attcaagtaa ttgcaaaata
    97801 tgtgttgata cacaaggagg atttttatta tggaaacagg tacagtaaaa tggtttaact
    97861 cagaaaaagg atttggattc atcactgcag aaaacggaaa cgatgtattc gttcatttct
    97921 cagctatcca aggcgacgga ttcaaaactt tagaagaagg ccaagcagta actttcgatg
    97981 ttgaagaagg ccaacgcgga cctcaagcaa caaacgttac taaagcttaa ttaacctata
    98041 ctaaaaaata aacgcccaga catttgcgtg tctgggcgtt tttgtctatt ttctttaaaa
    98101 agcgatgaga gtatttttct gcactttgta gtataatttc aaaagaacat tagaggcagg
    98161 agaagaggaa gatattttga aaccaagaac ttatgcagtc gttgatatcg aaacgactgg
    98221 gacgaatcca aaagaagatc ggatcatcca atttggctgc gtcatgattg aatcaggtcg
    98281 gatcacttca cgtttttcga tcgatattca tccagggcgg aagatttcaa aacaaatcca
    98341 gcatttaaca gggatcacga atcaacgcgt ccaaaaagcg ccttatttcg aagatgtcgc
    98401 ccaaacgatt tacaatcttt tggcagacac catatttgtc gcgcataata tttattttga
    98461 ttataatttt ttgaaccatg aactcatgcg atgcggactt cctagtttga agataccagg
    98521 catcgataca gtagaacttg cacaaatttt cttgccgacg gaaccaagct ttcgcttagc
    98581 tgatttgtca gaaagccttg gatttattca tgagaatcct catcaggcag atagtgatgc
    98641 cgaagtgacg ggtcaacttc ttttgctgat cgaagaacgg atgagaaaat tgccaatcat
    98701 cacgttagag cagattgcgc gattaagtag acacacaggt atggatacga gtcgtttcat
    98761 ttatcatgtg attgaagaaa tgaaagaaaa accagagcca cttgatccct cattagaaat
    98821 cgtcgatggg ctagctttgc agaaaaaaga agtggaacta ttcatatacg tccattatgg
    98881 cgagcggaca tatccaagaa aaaaacaagc aaaagaaaaa atgtttggta aaacactgat
    98941 gtatcgaaaa gaacagaaca gactgatgaa tgcggtctac gaccatttca caaaagatga
    99001 atcaaaagat ttgatgatcg aagcagctac aggaatgggt aaaacaatcg gttatctgct
    99061 gccattgagt tatttggcta cacctgaaaa acccgctgtc atcagtaccg tttcgctagt
    99121 tttgcagcag cagatcatag aaaaagacat tccattgctg aatcaattgc tagatcagcc
    99181 catacaacct gtaattatca aaagctatcg ccactatatt gatttacagc gttttaaagg
    99241 cacacttgtg gaaccgccag aacaaaaaca atatgctttg tatcaaatgg cggtcttagt
    99301 ttggctgacg caaacgaaga ccggtgattt ggatgaatta catttaacaa atttgaacca
    99361 ttcattcttt gcagatatcg cgcacagagg cactggattt ttagcaagaa atcagtcatt
    99421 ttacgaacaa gactttgttc gtttcttgca aaagaaaatc aggcaaagta attttttgat
    99481 tgtcaatcat gcgtttttaa tacaagaaac acagcgaaaa gaaccattgc ttccagctag
    99541 tccatttttg ttgatcgatg aagtacatca tttgccggaa atcgctgaaa aagtaaatga
    99601 caaacgatta agtattaact atttccataa acaaatccag caattagaag aaccaaatca
    99661 gctgtttgac cgaatacaaa gctatttacc gaaagaacat gaagccttac gctggttatc
    99721 gatttatcga gaagaacttt ctgcgctatg cgaagcacag atttgtatgg cagaaggatt
    99781 aatgagttta gtgagcggca agcaacctaa cggacagtat ccagaagaag tcatgacgac
    99841 aaaagagatg ttggatcagc tgccactgga atctgggaca gccattgatc acctgcagct
    99901 tttttatcag gagatccagc agctacagtc acaaatgcgt ctgacttttg agattatcca
    99961 agaaagctgg acaaaccaga tgcggatcga tttagcaagt ttatatagct tatttgatca
   100021 attagacaag cagtacttgc tgatggatca atggctggaa gactggcgag atcatttgat
   100081 ccattggttc gttcctggga acacagcgca gcagatgatt tttcatctcc atgattttca
   100141 agcggctatg ttgccgtcga ctgtttggta tcctcgatat gatcgtattc tttatattgg
   100201 aggaacgctg aagatcggcc ctaatcgaca ctatctctct aagcggcttg gcattgaagc
   100261 agcacctctt aaagtgattg cctctcctta tgattatgag aaacaggcaa ggatctatgt
   100321 gccaaaagag gcacctgccg tccatcaagt cagcaatcaa gcatatatcg attatttaga
   100381 gacagcactt acaggtctga tcgaacaaga agatcggcca atacttgtgt tattcacttc
   100441 tcatgatgtt ttgcagaagg tctatcagaa aatgcatctg tctatgctag aaaaaggacg
   100501 agaaatacta gctcaagggt ttggcggaag ccgggagaag cttttgaaac gcttcatttt
   100561 gtcagaaaaa agcgtattgt ttggcgctga cagtttttgg gaaggtgtag atttgcctgg
   100621 agatgctttg cagatcgttg tagtcacacg tttacccttc gataatccgc ttcgcccgat
   100681 ggtcaaagct aggaacgctt atttagaatc agaggggatc aatccttttt accaggaatc
   100741 cgtacctaaa gcagctttga agttacgcca agcattagga cgcttgataa ggacggagac
   100801 agatcgtggc gtattgctta ttttggatcg aagactagtt actgcaaaat atggtgcacg
   100861 gatcatccat gcattaccga aaaaagtacc gatcaaagag ctagctatgg aggaaatcta
   100921 tcaggatatc catgaattct taaagaaaaa tgaagaagga agttagagga gctgtctttt
   100981 ttcataatta aaatctgcta taatgaaaag gaatgaagat aaaggagcga cgacccttga
   101041 agaaaaaaca gacaaaggaa aaaacgatta atcgcgtgtt acttggcttg atcgtatttt
   101101 tattagcggt catcgtgatc agctcgattt tttacttgcg ttccagtcgt ccggcggtgc
   101161 aggcgaagaa agaagcagta gaaatcgcaa agaaatatgc aaatcttgag gaagccgatc
   101221 atttttattg gtttactcga aagaagacat acttttcact gacaggtaca aatgataaag
   101281 gaaaagaaat cgccgttatc attcctaaat ctggtgaaaa agtaaaagta ttggatcaaa
   101341 caaagggact gactgaaaat gaagcaaaac agacaattgc tgcggcccat cctgaaatcc
   101401 aaatcgaaaa agctgcttta gggatgtatg atgatcagcc tgtgtgggaa gtagtaggaa
   101461 aagaaacaaa tgggaaactg aattattacc tgattggctt tgaatctgga gatgaagtca
   101521 agacaatcaa gggaatttaa aaggtaaagg aatgaatggg atggagttat caaaaagaac
   101581 aaaacgatta gaaccgtctg tcactttggc agctgcggca aaggccaagg cattaaaagc
   101641 caaaggcaga gatgtgctga gtttgactgt gggagaaccg gattttgcga caccagaaaa
   101701 catccaagaa gcagcaatcg aagcaatccg caatgggaaa gctagctatt atacaccaac
   101761 agcaggaatc ccagagcttc gacaggcaat cgttgattat ctgaagaaaa actatggact
   101821 tgtctatgaa ccttcacaaa cagtcgtaac agacggagcg aaatttgctt tgtataccct
   101881 tttccaaacg atccttgacc cgcaagatga agtcatcatt cctgtgcctt actgggtcag
   101941 ttacggtgag caagtaaaac tggcagaagg acttcctgtc tttttgaaag gagaagaatc
   102001 caatagctgg aaagttactg ttgagcagct agaacaagca cgttcagaaa aaacaaaagc
   102061 cgtaatcatc aattctccat cgaatccgac tggaatgatt tatagcaaga atgaactgca
   102121 ggcaatcggt gaatgggcag taaaaaatga tattttgata gttgctgatg atatttatgg
   102181 ccgtttagtt tataatggca atgagtttac tccaattgca acgatttcag aagcaatcaa
   102241 aaatcagacc atcatcatca acggcgtgtc taaaacatat gcgatgacag gctggcgcat
   102301 tggttatgcg gtgggaaatc ctgtgatcat caatggaatg atcgctgttg cttcccaatc
   102361 aactagcaat ccgacagcag tcagtcaata tgcagctgtt gaagcattga aaggcgagca
   102421 agatacagtg gaagaaatgc ggaacgcctt tgaagaacgc ctgaatacgt tatatccgct
   102481 tgtggcagaa ctgccgggtg tttctcttga aaagccacaa ggagcttttt atctttttcc
   102541 taatgtaaaa gaaacgctac gcatgtgtaa atatgaaaat gtcacacaat gggtagaaga
   102601 tcttttagaa gaaacagggg tagcgcttgt gactggcgaa ggctttgggg caccagaaaa
   102661 tgtccgcatg agttatgcca ctgatcgcgc tacgttagaa gaagcggtac gcagaatcaa
   102721 gcaatttatt gagagtaaaa gtcaaaatta atcctgaaga aattcaagga atataaaagg
   102781 agagtcatac gtggaacaaa ttcaaatcat cgattcgaaa aaccatgtgg gagaaacagt
   102841 aacaatcggc gcttgggtcg caaataagcg atcaagcgga aaaatcgcat ttttacaatt
   102901 aagagacgga acagcctttt tccaaggtgt agttgtaaaa agcgaagtgc cggaagaagt
   102961 tttccaaaca gctaaaaatc tgcaccaaga aacatccgtg ttagtaactg gagaaatccg
   103021 tgaagacagc cgttcaaaat ttggttatga aatcggaatt acaaatgtgg aagtggtaag
   103081 cgagagccac gattatccga tcacaccaaa agaacacgga acagacttct tgatggatca
   103141 tcgtcattta tggctacgtt cttcaagaca acatgcgatt atgcagatca gaaatgaaat
   103201 cattcgtgca acgtatgaat tctttaatca acatcatttt gtcaaaatcg atccgccgat
   103261 cttgactggt tccgcaccag aaggcactac ggatctattc gaaacaaatt actttgatca
   103321 aaaagcttat ttatctcaaa gtggccaatt atacatggaa gctgctgcta tggctttcgg
   103381 aaaagtcttt tcattcggtc cgactttccg tgctgaaaaa tcaaaaacac gacgtcattt
   103441 gattgaattc tggatgatcg aaccagaaat ggctttcact catcaagaag aaagtttaga
   103501 agtacaggaa caatatgtag cattcttagt acaaaatgtt ttagatcatt gcgaatacgc
   103561 attagatgta ctaggacgag acaaagaagt cttaaaaact tatacaaaat tgccattccc
   103621 tcgtattact tatgatgatg cgatcgaatt actgaagaaa aatggatttg atgacatcga
   103681 atggggcgaa gactttggtt cacctcatga aacgttcatt gcgaattcat tcgaacagcc
   103741 tgtctttatc ctaaactatc caaaagctat caagccattc tacatgaaac cacatccaac
   103801 aagagaagac gtggtaattt gtgcagatat gatcgcacca gaaggttacg gtgaaattat
   103861 tggcggaagc gaacgggcaa cggactatga tttcttgcta gaacaaatcc gtaatcacgg
   103921 tttggatgaa aaagaatatt catggtatct tgatctacgt aaatacggtt ctgttccgca
   103981 ctctggtttt ggtctaggcc ttgaacgaac agtcacttgg attgctggta tcgaccatgt
   104041 gcgtgaagct attccattcc cacgtttgtt gaaccgaatt tatccataag aggtgatgaa
   104101 aaagctgttc tgcatcaagt aattagaaca gccaagcaaa aacagctgtt catgtttttg
   104161 aattggcggg acttattacc gcagatgtaa gcttttgaat accgtttagt ggagaggttg
   104221 tgaaaaagct gtttagtttc gagtattaag aaaaattttg tggaaatggc tttccacatt
   104281 tttgcataaa tttggcttaa taccgagaaa ctggcttttg aacaccgttt aaggaagagg
   104341 ttgtgaaatc agtgccttga cctgagtatt agagaaacaa aacggaaaaa tagcttctca
   104401 tattttaccg tttttttagc taatatcgag ggtcagctga ttgaacaccg tttatatcaa
   104461 gaggttgtgc gcctgccgtt cagctccgag tcacaaggag taatttcaaa aaacagtttt
   104521 tcatgtttga tgactattgt gacttgtgac cgaggagttg gccggagagc accgtttatt
   104581 ctaaaaa
//
LOCUS       DBBGSZ010000008        83647 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.008, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000008 DBBGSZ010000000
VERSION     DBBGSZ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 83647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83647
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.008"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..566)
                     /gene="ytpR"
                     /locus_tag="ACIZE5_000800"
     CDS             complement(<1..566)
                     /gene="ytpR"
                     /locus_tag="ACIZE5_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HGC6107964.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILV"
     gene            complement(771..1235)
                     /locus_tag="ACIZE5_000801"
     CDS             complement(771..1235)
                     /locus_tag="ACIZE5_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGC6107965.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(1257..1577)
                     /locus_tag="ACIZE5_000802"
     CDS             complement(1257..1577)
                     /locus_tag="ACIZE5_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HGC6107966.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            complement(1721..2800)
                     /gene="pepA"
                     /locus_tag="ACIZE5_000803"
     CDS             complement(1721..2800)
                     /gene="pepA"
                     /locus_tag="ACIZE5_000803"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HGC6107967.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            3000..3350
                     /locus_tag="ACIZE5_000804"
     CDS             3000..3350
                     /locus_tag="ACIZE5_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HGC6107968.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            3573..4520
                     /locus_tag="ACIZE5_000805"
     CDS             3573..4520
                     /locus_tag="ACIZE5_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGC6107969.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(4577..5995)
                     /gene="pepV"
                     /locus_tag="ACIZE5_000806"
     CDS             complement(4577..5995)
                     /gene="pepV"
                     /locus_tag="ACIZE5_000806"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HGC6107970.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            6144..6989
                     /locus_tag="ACIZE5_000807"
     CDS             6144..6989
                     /locus_tag="ACIZE5_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HGC6107971.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            6993..7433
                     /locus_tag="ACIZE5_000808"
     CDS             6993..7433
                     /locus_tag="ACIZE5_000808"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HGC6107972.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            7483..7677
                     /locus_tag="ACIZE5_000809"
     CDS             7483..7677
                     /locus_tag="ACIZE5_000809"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107973.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            7813..8499
                     /locus_tag="ACIZE5_000810"
     CDS             7813..8499
                     /locus_tag="ACIZE5_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6107974.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(8907..9596)
                     /locus_tag="ACIZE5_000811"
     CDS             complement(8907..9596)
                     /locus_tag="ACIZE5_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6107975.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(9571..11700)
                     /locus_tag="ACIZE5_000812"
     CDS             complement(9571..11700)
                     /locus_tag="ACIZE5_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HGC6107976.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            complement(11748..13085)
                     /locus_tag="ACIZE5_000813"
     CDS             complement(11748..13085)
                     /locus_tag="ACIZE5_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HGC6107977.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            complement(13338..13697)
                     /gene="rplT"
                     /locus_tag="ACIZE5_000814"
     CDS             complement(13338..13697)
                     /gene="rplT"
                     /locus_tag="ACIZE5_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HGC6107978.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(13750..13950)
                     /gene="rpmI"
                     /locus_tag="ACIZE5_000815"
     CDS             complement(13750..13950)
                     /gene="rpmI"
                     /locus_tag="ACIZE5_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HGC6107979.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(14022..14546)
                     /gene="infC"
                     /locus_tag="ACIZE5_000816"
     CDS             complement(14022..14546)
                     /gene="infC"
                     /locus_tag="ACIZE5_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HGC6107980.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(14590..14715)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            14866..15498
                     /locus_tag="ACIZE5_000817"
     CDS             14866..15498
                     /locus_tag="ACIZE5_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HGC6107981.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(15500..16405)
                     /locus_tag="ACIZE5_000818"
     CDS             complement(15500..16405)
                     /locus_tag="ACIZE5_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGC6107982.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(16490..17149)
                     /locus_tag="ACIZE5_000819"
     CDS             complement(16490..17149)
                     /locus_tag="ACIZE5_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HGC6107983.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            17465..18409
                     /gene="mvk"
                     /locus_tag="ACIZE5_000820"
     CDS             17465..18409
                     /gene="mvk"
                     /locus_tag="ACIZE5_000820"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HGC6107984.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            18402..19379
                     /gene="mvaD"
                     /locus_tag="ACIZE5_000821"
     CDS             18402..19379
                     /gene="mvaD"
                     /locus_tag="ACIZE5_000821"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HGC6107985.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            19392..20477
                     /locus_tag="ACIZE5_000822"
     CDS             19392..20477
                     /locus_tag="ACIZE5_000822"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HGC6107986.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            20474..21538
                     /gene="fni"
                     /locus_tag="ACIZE5_000823"
     CDS             20474..21538
                     /gene="fni"
                     /locus_tag="ACIZE5_000823"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HGC6107987.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(21787..22590)
                     /locus_tag="ACIZE5_000824"
     CDS             complement(21787..22590)
                     /locus_tag="ACIZE5_000824"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HGC6107988.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(22610..23452)
                     /gene="kduI"
                     /locus_tag="ACIZE5_000825"
     CDS             complement(22610..23452)
                     /gene="kduI"
                     /locus_tag="ACIZE5_000825"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008697 -
                     4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0045490 - pectin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HGC6107989.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(23468..24475)
                     /locus_tag="ACIZE5_000826"
     CDS             complement(23468..24475)
                     /locus_tag="ACIZE5_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="HGC6107990.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(24482..25126)
                     /locus_tag="ACIZE5_000827"
     CDS             complement(24482..25126)
                     /locus_tag="ACIZE5_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HGC6107991.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(25226..25984)
                     /locus_tag="ACIZE5_000828"
     CDS             complement(25226..25984)
                     /locus_tag="ACIZE5_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HGC6107992.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(26111..27262)
                     /gene="fucO"
                     /locus_tag="ACIZE5_000829"
     CDS             complement(26111..27262)
                     /gene="fucO"
                     /locus_tag="ACIZE5_000829"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008912 - lactaldehyde reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HGC6107993.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(27344..27655)
                     /gene="rhaM"
                     /locus_tag="ACIZE5_000830"
     CDS             complement(27344..27655)
                     /gene="rhaM"
                     /locus_tag="ACIZE5_000830"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0062192 - L-rhamnose mutarotase activity
                     [Evidence IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HGC6107994.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(27657..28502)
                     /gene="rhaD"
                     /locus_tag="ACIZE5_000831"
     CDS             complement(27657..28502)
                     /gene="rhaD"
                     /locus_tag="ACIZE5_000831"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008994 - rhamnulose-1-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HGC6107995.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(28516..29772)
                     /gene="rhaA"
                     /locus_tag="ACIZE5_000832"
     CDS             complement(28516..29772)
                     /gene="rhaA"
                     /locus_tag="ACIZE5_000832"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008740 - L-rhamnose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HGC6107996.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(29769..31229)
                     /gene="rhaB"
                     /locus_tag="ACIZE5_000833"
     CDS             complement(29769..31229)
                     /gene="rhaB"
                     /locus_tag="ACIZE5_000833"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008993 - rhamnulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HGC6107997.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            31382..32251
                     /locus_tag="ACIZE5_000834"
     CDS             31382..32251
                     /locus_tag="ACIZE5_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGC6107998.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(32377..33276)
                     /locus_tag="ACIZE5_000835"
     CDS             complement(32377..33276)
                     /locus_tag="ACIZE5_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6107999.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(33441..34265)
                     /locus_tag="ACIZE5_000836"
     CDS             complement(33441..34265)
                     /locus_tag="ACIZE5_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HGC6108000.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(34276..35571)
                     /locus_tag="ACIZE5_000837"
     CDS             complement(34276..35571)
                     /locus_tag="ACIZE5_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HGC6108001.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(35587..36066)
                     /locus_tag="ACIZE5_000838"
     CDS             complement(35587..36066)
                     /locus_tag="ACIZE5_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HGC6108002.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(36072..37100)
                     /locus_tag="ACIZE5_000839"
     CDS             complement(36072..37100)
                     /locus_tag="ACIZE5_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HGC6108003.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(37117..38223)
                     /locus_tag="ACIZE5_000840"
     CDS             complement(37117..38223)
                     /locus_tag="ACIZE5_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGC6108004.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(38452..41049)
                     /gene="adhE"
                     /locus_tag="ACIZE5_000841"
                     /gene_synonym="adhC"
     CDS             complement(38452..41049)
                     /gene="adhE"
                     /locus_tag="ACIZE5_000841"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HGC6108005.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(41354..41734)
                     /gene="yajC"
                     /locus_tag="ACIZE5_000842"
     CDS             complement(41354..41734)
                     /gene="yajC"
                     /locus_tag="ACIZE5_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGC6108006.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(41831..42976)
                     /gene="tgt"
                     /locus_tag="ACIZE5_000843"
     CDS             complement(41831..42976)
                     /gene="tgt"
                     /locus_tag="ACIZE5_000843"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HGC6108007.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            43194..43892
                     /locus_tag="ACIZE5_000844"
                     /pseudo
     CDS             43194..43892
                     /locus_tag="ACIZE5_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
     gene            complement(44060..46699)
                     /locus_tag="ACIZE5_000845"
     CDS             complement(44060..46699)
                     /locus_tag="ACIZE5_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGC6108008.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(47318..48349)
                     /gene="queA"
                     /locus_tag="ACIZE5_000846"
     CDS             complement(47318..48349)
                     /gene="queA"
                     /locus_tag="ACIZE5_000846"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HGC6108009.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            48542..49717
                     /locus_tag="ACIZE5_000847"
     CDS             48542..49717
                     /locus_tag="ACIZE5_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HGC6108010.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            49721..50362
                     /locus_tag="ACIZE5_000848"
     CDS             49721..50362
                     /locus_tag="ACIZE5_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6108011.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            50359..51276
                     /locus_tag="ACIZE5_000849"
     CDS             50359..51276
                     /locus_tag="ACIZE5_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC6108012.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYDQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            51273..51944
                     /locus_tag="ACIZE5_000850"
     CDS             51273..51944
                     /locus_tag="ACIZE5_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6108013.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATDGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(52486..52974)
                     /locus_tag="ACIZE5_000851"
     CDS             complement(52486..52974)
                     /locus_tag="ACIZE5_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HGC6108014.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(53175..53441)
                     /locus_tag="ACIZE5_000852"
     CDS             complement(53175..53441)
                     /locus_tag="ACIZE5_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HGC6108015.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQSNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(53441..53704)
                     /locus_tag="ACIZE5_000853"
     CDS             complement(53441..53704)
                     /locus_tag="ACIZE5_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HGC6108016.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSGFTNIDDIDWEAL"
     gene            complement(53849..54172)
                     /locus_tag="ACIZE5_000854"
                     /pseudo
     CDS             complement(53849..54172)
                     /locus_tag="ACIZE5_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016609629.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 127 protein"
     gene            complement(54335..55525)
                     /locus_tag="ACIZE5_000855"
     CDS             complement(54335..55525)
                     /locus_tag="ACIZE5_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008376093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinan endo-1,5-alpha-L-arabinosidase"
                     /protein_id="HGC6108017.1"
                     /translation="MTAINGVHDPTIIEHEGTFYLYSTDTQQPKTAGVPIRSSKDLIH
                     WQFEKQALSEMPEPAVKWSKAQGLWAPEVIRYKDEFRMYYSASTFGSTTSFIGLATAS
                     DPLGPWEDQGEVVKTNATLAQHNAIDANIAFDRSGEQWFVYGSFFGGIYIAPLNKETG
                     KLQEKSYGQRIAFRPKTVDTAIEGPFIYYHPETDYYYLFVSFDSLNDSYNIRVARAKE
                     ITGPYLDWHGTAMTDQEKTPTEVGTKLLGSYQFSEETVVYAPGHNSIFTQSNKESFVV
                     HHARRKPFSDQFHLQIRKLYWLESGWPVISASIYQGSVSRMPEQETLLGKWEIIQFDY
                     ESQIISSQQHEITELKKEGRSYLWEGNEFVPYYEYIDQKERLFFSGINDQGVAFLGRK
                     VCEE"
     gene            complement(55578..55844)
                     /locus_tag="ACIZE5_000856"
     CDS             complement(55578..55844)
                     /locus_tag="ACIZE5_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6171 family protein"
                     /protein_id="HGC6108018.1"
                     /translation="MTCKGCEVKDVAVAAQEDIESLIAEQLSLERDLALPEIVSRRIA
                     VCETCPLRLNHTCTKCGCFYRFRANLAKKNCPAGMWEQTGQLVK"
     gene            complement(55849..57294)
                     /locus_tag="ACIZE5_000857"
     CDS             complement(55849..57294)
                     /locus_tag="ACIZE5_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008376098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HGC6108019.1"
                     /translation="MTIKILHTKSGTTISKYIYGHFAEHLGRCIYEGLYVGEDSPIPN
                     KNGMRIDVVEALKNIQIPVLRWPGGCFADEYHWKDGIGPKENRKTMVNTHWGGVTENN
                     HFGTHEFFELIKQLQCDAYVNGNVGSGTVQEMSEWVEYITMDGISPMADLRRENGHEE
                     AWEMKFFGVGNENWGCGGNMRPEYYADLYRRYQTYVRQYGDKKIYKVAGGANVADYHW
                     TETLMKNAHWLMDGLSLHYYVHPQGWEEKGSALEFNEAEWQVTCEKAAYMDELLTRHS
                     AIMDQYDPEKRVGIIVDEWGTWFSAEPGTNPGFLYQQNTIRDAMVAAITLNIFHKHAK
                     RVHMANIAQTVNVLQAMILTDGEQMVKTPSYHVFDLYKVHQDAETIDSHGTSSDTITY
                     TISKKEDTIHLSVCNFATQGTEELSFSLETAINKVKEARYIVGDKMNAHNDFDHPEDV
                     AIQDFTAYDVEENKVSLRVPAMSVLTISLTV"
     gene            complement(57305..58927)
                     /locus_tag="ACIZE5_000858"
     CDS             complement(57305..58927)
                     /locus_tag="ACIZE5_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008376100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HGC6108020.1"
                     /translation="MTTKINMISRMIPVFLTSFFLMGCQTGEAAEQLIQKEWETTSKE
                     RVSIHDPSITTIHEENQELFYVFGSHLAQAKTSDLRTWEVPFSHEYESMEDNIIYGNT
                     KENLAETFKWAGYDDADSKGGYSLWAPDVIWNADYEWSNGDKGAYMLYYSASSTWRRS
                     AIGLAVAKTIEGPYSYSDTVIYSGFTEKDSTDGSDRNTNYQNTHLAKLIKDGKISGFS
                     ENWSIEAGLTYNTDYAPNAIDPALFYDEEGKLWMTYGSWSGGIFLLEVDPATGKPMYP
                     GEDSTTEDGRIIDRYFGIKLSGGYHQSGEGPYIVYDEKTDYYYLFVTYGGLAAKGGYN
                     MRLFRAEKPEGPYLDAQGNSPILDKGEQNVNYGIKLIGNYQFSFQQMGYRAAGHNSAI
                     IDENGQWSLVYHTRFNNGTEAHEVRVNRMYMNEEGWPVPAPYEYRGNEQVADALTEDE
                     IIGRYEIINHGTDNGTTMLKTQMIEFQKDGNVTGDLTGTWTYDAGYLVLTFEETTFKG
                     ILLTQEITEFEQQKLTFSTIGDNNESIWGIKE"
     gene            complement(58946..59902)
                     /locus_tag="ACIZE5_000859"
     CDS             complement(58946..59902)
                     /locus_tag="ACIZE5_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HGC6108021.1"
                     /translation="MAENYLEPIVLERADPWIYKHTDGYYYFTGSKPGYQEIELRRAK
                     TLKGLTDGEVKVIWTAHAEGSMSELIWAPEIHFIQGKWYIYFAAADHGEVRNDQHHHR
                     MFAIENAKENPFEGEWVEKGQIKTQFESFSLDATVFEHRNRLYYVWAQVDPNIPGNSN
                     LYLSEMENPWTLKGKQILLSIPYYEWEKIGFKVNEAPAALIRNGKVFITYSASATDEN
                     YAMGLLWADEESDLLNGYSWNKLKEPVFSSSERNSLYGPGHNSFTIDEEGKQDILVYH
                     ARPEKNDYSDPLENPNRHAYVQPFTWHKNGLPNFGEPGVIKA"
     gene            complement(59918..60334)
                     /locus_tag="ACIZE5_000860"
     CDS             complement(59918..60334)
                     /locus_tag="ACIZE5_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008376104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108022.1"
                     /translation="MNRKLERNLLRASAVWDVCIGLVTMFGYYPWFEEQGIAAFQNQN
                     QYEYLQSSLIGMISKVVLIVALATILMGVISWINAKNMRDKQINKGTIRWMIACVIIH
                     LIIYDVIGVVLYLLATTMYMSKNKAIKILKTENGIF"
     gene            complement(60343..61194)
                     /locus_tag="ACIZE5_000861"
     CDS             complement(60343..61194)
                     /locus_tag="ACIZE5_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6108023.1"
                     /translation="MNTQKKHIPSMIIAYLFLIVLCIIWVIPLIFSFATSFRSQTEIV
                     STGFRLLPVNWILDNYIAILTNTSTAPIMQWLWNSLFIAVTHTVLVVIVVSVTAYGYG
                     RTRFKYRDRIFYLLMGISMFPGVVNLIPSYKIIETFGWVNSSLAMIVPGLAGMGNIFL
                     VRQFMKGIPLEFDESARMDGADEFTIFSEIIVPLIKPVLIVAGLFSFTGSWNDFLWPV
                     IVYTDVSKMPITAGLLLLQDIYGNYRMIGQLMGSALIAIIPTVLLFLFAQKYFIESMN
                     LNAGIKG"
     gene            complement(61206..62096)
                     /locus_tag="ACIZE5_000862"
     CDS             complement(61206..62096)
                     /locus_tag="ACIZE5_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6108024.1"
                     /translation="MKGMKKKSINWASIAFIGPHMVLFIIFVCIPTVYGIYASFTQWN
                     LISDPVWVGLNNYKTLLFDSSSTFYTQFWNGLKNTFIFVLIMVPLQIIIPLMIAAALQ
                     HKKVKLKGLFQAVLYIPGLISVSAGSLIWSLIFHSRLGAVNNIFGFDFSWASRQPYAW
                     ILIFAVSIWGAIGGNMIIYRSALAGVNEDLYEAAEIDGAGSFQKFLNVTLPSIRFPLL
                     YTIVMTTAGAFNVFAQPLMMTGGGPNQSTTVLMMYIRSLAFSQGESIAGMASAMAVIL
                     GLIIMCVSVFQYFLLDRSNT"
     gene            complement(62141..63391)
                     /locus_tag="ACIZE5_000863"
     CDS             complement(62141..63391)
                     /locus_tag="ACIZE5_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGC6108025.1"
                     /translation="MKKKLIIIGALVAVVAIAFAGFKRYQSSEKEKYTINFWSPLTGD
                     DGAYMDKIVDEFNEQSGSDYKINHVITSDMYTKLSTVVSSKNGIPDLTLMHSYKVEEF
                     VNSNILDTVEPLVSHQPELQKGNYLDTAWNAGTIGGTQYTIPLDIHASAMYYNQDLLE
                     KYDVTSWLDDNIVTFDEMMSLAGKMDEGDYVVNNALLSWVILAQIRNLGGTISDEAGN
                     PTVNTPEMKEALERIKALTDAGLMTPYGEDGYLMFQGGNVLLSTDGTWTSTAHDAVEG
                     LNWGVTNIYSTSDDIATNRAASHMFGMLKSESRTDEKEEVIAQFLEFVRTNSIEWAKA
                     GQIVASKDILESDDYQQYPQSFFTSTSEEEDTLYIFDYVYFSYVLEALDVYCTDIAYS
                     ELDLDEGLATMQQYVEDKIAEVAK"
     gene            63705..64595
                     /locus_tag="ACIZE5_000864"
     CDS             63705..64595
                     /locus_tag="ACIZE5_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HGC6108026.1"
                     /translation="MQLEINQEALPVYEALASNVRIKIIQLLAKNKMNVKELAQELGL
                     SSAIITVHIKKLEEAKIIKTERVGQKKISSLRVDHIDINFPEKIFNAFDTRETSIPIG
                     HYTNYFVEPTCGLATLSGFIGPVDEPKFFMDPNRMDGRILWFTKGFVEYQSPNFLSPD
                     EKLEMMEISMEISSEFPFSNNNWPSDITFSLNGITLGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRIMEHGTYMEGEPLSDVTIKDIPTYEDTWHLRVEVKEEAENIGGCT
                     LFGKGFGNYDQDIKIKMFYS"
     gene            complement(64737..66560)
                     /locus_tag="ACIZE5_000865"
     CDS             complement(64737..66560)
                     /locus_tag="ACIZE5_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGC6108027.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(67158..69863)
                     /locus_tag="ACIZE5_000866"
     CDS             complement(67158..69863)
                     /locus_tag="ACIZE5_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HGC6108028.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(70169..71116)
                     /locus_tag="ACIZE5_000867"
     CDS             complement(70169..71116)
                     /locus_tag="ACIZE5_000867"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HGC6108029.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            71306..71575
                     /gene="rpsN"
                     /locus_tag="ACIZE5_000868"
     CDS             71306..71575
                     /gene="rpsN"
                     /locus_tag="ACIZE5_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HGC6108030.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(71751..72113)
                     /locus_tag="ACIZE5_000869"
     CDS             complement(71751..72113)
                     /locus_tag="ACIZE5_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HGC6108031.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(72124..73245)
                     /gene="alr"
                     /locus_tag="ACIZE5_000870"
     CDS             complement(72124..73245)
                     /gene="alr"
                     /locus_tag="ACIZE5_000870"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HGC6108032.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(73261..73611)
                     /gene="acpS"
                     /locus_tag="ACIZE5_000871"
     CDS             complement(73261..73611)
                     /gene="acpS"
                     /locus_tag="ACIZE5_000871"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HGC6108033.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(73741..75252)
                     /locus_tag="ACIZE5_000872"
     CDS             complement(73741..75252)
                     /locus_tag="ACIZE5_000872"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGC6108034.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(75574..76926)
                     /gene="murF"
                     /locus_tag="ACIZE5_000873"
     CDS             complement(75574..76926)
                     /gene="murF"
                     /locus_tag="ACIZE5_000873"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HGC6108035.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(77079..78155)
                     /locus_tag="ACIZE5_000874"
     CDS             complement(77079..78155)
                     /locus_tag="ACIZE5_000874"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HGC6108036.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            78351..80096
                     /locus_tag="ACIZE5_000875"
     CDS             78351..80096
                     /locus_tag="ACIZE5_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/UbiB family protein"
                     /protein_id="HGC6108037.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(80376..80813)
                     /locus_tag="ACIZE5_000876"
     CDS             complement(80376..80813)
                     /locus_tag="ACIZE5_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HGC6108038.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(80797..82170)
                     /locus_tag="ACIZE5_000877"
     CDS             complement(80797..82170)
                     /locus_tag="ACIZE5_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108039.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(82492..82980)
                     /locus_tag="ACIZE5_000878"
     CDS             complement(82492..82980)
                     /locus_tag="ACIZE5_000878"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6108040.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(83002..83604)
                     /locus_tag="ACIZE5_000879"
     CDS             complement(83002..83604)
                     /locus_tag="ACIZE5_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HGC6108041.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT        23965 a        18016 c        15259 g        26407 t
ORIGIN      
        1 aatactaaga ttcctttttt tgctggagca tttggcaaat gcaattcacg agcggaacag
       61 atcattccat agctatctac ccctcgcaaa gttcctggcc agatcatcat tccatctggc
      121 atcatagctc ctggttttgc aacgacaact ttttgtccag cttcgatatt gggtgcaccg
      181 caaacgattt gcaatactgt accattgtct acttctgtct cagtaatcga taaatggtca
      241 gaatcaggat gtgggacgca tgtttttacg tacccgacaa cgatcttcgg ttcatgatca
      301 gcttcaagct gttcttcgaa tcctgcttct ttgatcaatc gattcaattt cgctaattcc
      361 tcatctgtta agcttacttg gccgttccct tcgattgtta gatgatcgga gatatggaaa
      421 aagttccaag caacaacttg accttgttca tctttgatcc gagcaacatt ccatttgcgt
      481 tcaacagtgt tttctgttcc tttatcgtcg gctataataa ccatcaaggt gtctccgacg
      541 tgtgctttgt tataagcaaa aatcatgttc tttcctccat tatcctttgc tgagatttat
      601 cttaacaaaa aattgcattc actgcatgaa atttttttca tgctttattt ccgaagaagc
      661 ctcttctgga acaccattta ttcgtaacaa gggactgtga caagactttt gtcacagtcc
      721 ctttactgtt ttagttaatt gattaaaaag gtcgtacaag ttccacttgc ttaattactt
      781 ggctgttctt cttcgtcaga aacgatcaag acatcacaag gtgaatgacg tatcacgtag
      841 ctggctacac ttcctgtcat aaagcgttcg actgcattta gacctgactg cccaaccatg
      901 attagatcga tctcatattt ttttggcaat ttgactgcca tggattcacg aacagaacca
      961 tatgcaataa ttccttctat atttgtgtaa tcaacagatt tcccatattc tttacattct
     1021 tcgatcattt ccttggctgt ttcagtttgc tgatcgacta gattttgatc aataggtgca
     1081 tagcccataa agttataaaa ttgctgatcg attacgtttg ctacatatac tttcccatta
     1141 ttacggcgag ccacttctac cgcttttttg aaagcagcaa gtgcttgttc actaccgtcg
     1201 atacctacta aaatattctt atattcttga ttcatcttga cccctcctaa cagatgtcag
     1261 ccttttgtta cactttctag gaacgattcg atttcctgtt ttgttttacg atctttattc
     1321 actagacgac ctaattcttt tccgtcttgg atcacgacaa aacttgggat accaaaaatg
     1381 ttccattcag cggctacatc tatgtacttg tcacggtcta cttcaataaa ttgccaatca
     1441 gaaaagtcat tttcaatttc aggcatttgc ggtttgataa aacggcagtc tccgcaccag
     1501 ccggcagtaa agaaaaatac actctttcca gtttctacgt agcctgctaa ttcttctaaa
     1561 ctatttggga taatcattct ttgtcctcta ctttctgttt atgtattttt caattaaatt
     1621 atacaccttt ctttcgaact aacaaacatt gatcctcttt ttataaaaaa aatctggcaa
     1681 aaagcaatct tttgccagat tttatagttt cactatcgca ttattttccg tatacgatcg
     1741 tatttactgt tgatttatcc aaacctttca gtgtttgaat caacatttct cgtgcagctt
     1801 caaaatcgcg aatactgaac atcgtttgat gcgtatggat ataacgtccc actacgccaa
     1861 tcactgtact tgggattcct tcgttttgtg tatgagcagc acctgcatct gtaccgcctt
     1921 ttgaaacaaa gtattgataa gggatattgt ttgtttcagc gatatccagc aagtactcgc
     1981 gcaaacgagg aagcatgatc aaacctggat cttggatacg catcaatgta ccttctccta
     2041 aatgtccgaa tgtgccattt ttcgtcactg tatcatctgc tgcagagcag tctactgcaa
     2101 agaacagatc tggcttgaat ttattgacag aagctttaga accacgcaag cctacttctt
     2161 cctggacatt cgcgcctgca atcaatgtat gacctaatgt ttcattttgc aacgcttcta
     2221 aagcttctaa taccattgta cagccatagc ggttgtccca tgatttactg ataatattct
     2281 ttccgttggc tgttttgatc gtttcagcgt aaggaacgat tgtgtctcct ggaaggacac
     2341 cgtaactcat tgcctcttct cttgattcaa acccagcatc gaacaaaata tcggttactt
     2401 ctactgattt ttgtccgctt gttcctcgca ataaatgtgg gggaacggaa gaagaaatac
     2461 atggataatt cttaccagta gaggttttaa gtgtaaaacg ctgagcagaa acaacgtaag
     2521 gattccagcc gcctagaggt acgactttaa aaagcccgtt ttcttggatt tgtgtcagca
     2581 tgaatccgac ttcatccata tgtgctgcga ccattacacg gggtgcatcc gcttcttcat
     2641 gatggcgcag accaaaaatg ccgcccaaac catctaactg taactcatct accagcggtt
     2701 ccatatgact ttccatataa gcgcgaacat cttgttcaaa accgcttgtt ccttgtaatt
     2761 ctgttaactc tttgattcgt tgaaatgttt tttcttccat atgctattcg tctaaatttc
     2821 agactaaact cctctcagac ttatattgat ctgcggataa aatatgattt tttctgcaga
     2881 ccgatcgtat ttattatagc ttattttttc tggtagcggt tatttatttc aaagaaaata
     2941 tgagagtgtg gtaaaataag cacaaggagt aacaagtgag aagaaggagg tatgtccaca
     3001 tgtatgaaga aagcgaacta agctatttta aaggcgggtt agcagttgga atcggtctag
     3061 gattattgag cggggtagct tcaacgattt ggtatcatcg caaaaaagta ttgtcagcag
     3121 accaagtact tgaaaatatc aagtcatctt ttctaaaaga aggtgcaatc gaaggttctt
     3181 ggatctcttt tgaaaaggaa cctattagga aattcgccgt tcggtcgagt gcttatcggg
     3241 gaggtctttc tcgaatagaa gatggcgaaa ctgtttatta tgaattttta gcagatgctc
     3301 atacaggaac cgtattagaa atttcaagaa aaaaaggtgc aacagattaa tacgtcaaaa
     3361 aagtgagaga acgaatacgc acccactatt caaaagagag gtatcatgtc cttcttttgt
     3421 agtgggtggt tttttagata gagctttcca aacatatatt ccagtatttt ctttttaaat
     3481 aaatgatatt tagcgggaaa aactagcatt tcctttgatt atgaggtatt tttaatttag
     3541 cttttgtttt ctatagttaa ggagagtgaa aaatggaaca acaagaaaaa attgctgttc
     3601 tgattccttg ttacaatgag gaagcaacaa tttcaacagt cattgcagac tttaaacgag
     3661 aattaccaga agcagatatt tatgtctatg ataataattc gaccgatcga acatacgaat
     3721 tggccgttca aggtggagca atcgtaaaaa aagaacctcg tcaaggaaaa ggaaatgtga
     3781 tccgccaaat gttctttgat atcgatgccg actattattt aatggtagat ggcgatgata
     3841 cttatcctgc agaagctgta catggtttgc tcgagaaatt acgttctggt gaagcagata
     3901 tggtcattgg tgatcgccta tcaaatggaa cctactttga tgagaataag agacctttcc
     3961 acgattttgg aaataacctt gttagaaata caattactag aatgtataaa acaaaaattc
     4021 ttgatgtcat gaccggctat cgaggattca atcgtatctt tgtcaaaagt tttcctatta
     4081 tgagttctgg ttttcaaatc gaaacggaat tgacgatcca tgctttagat aaaaaattca
     4141 agttcgttga aatcccaatc gattatcgtg atcgtcctga aggcagcgaa tcaaaattga
     4201 atacattctc tgacggattc aaagtgatca tgatgattat taaaatgttt aaagattata
     4261 agcctttgct tttctttggg atttggacca tcttcttctt tttatttgga ttggtcacgg
     4321 ggattcctgt gattcgcgaa tatatgctga caagctttat tacacgcatc ccttctgcga
     4381 ttttaagtac tggattgatg actttagcac ttctttcatt agtaacaggg ttgattttgg
     4441 atacagtcgt cacgaacgct aagaaagaat atgaattgaa tctatatcat gtttatcatg
     4501 aataccacag tagaaagtaa aaaaaggatc aagactgcaa aaataatttg caattcttga
     4561 tcctcttttt aattaattat ttcgccaaac gatagatggc atctgcatag attgctgttg
     4621 ctctgaacaa gtcatcaaga ctcataaatt cgtttgcttg atgcattgta tcagtatatc
     4681 ctgggaacat cgctccataa gcaacgccac gtttcaacaa acgtccgtaa gttccgccac
     4741 cgatgatttg ttcgtagcct ttttctccag tgtggtcttc atagacttgc aataatgtag
     4801 ccaccaatgg atcatccatt ggtacgtaat gtggttccat tacgcgagca cctcgagtaa
     4861 ctgttgcgcc ttcttgcccc actgtttgtt cgatgtcact ttgcaatccg tctactgtta
     4921 caccttttgg aaaacggaaa ttcatattga tgaagttcgc ttcctctgta ccattttctt
     4981 caaaagcaaa tagtccagca ttcattgtca atttgcccat tttttcatct tcataagcga
     5041 ctcctagttt ttctccataa aaatcttcat ggacataagc agctgctaca tggataaatt
     5101 gtttagcaga tcctaggaat tcatagttat ctaagaacaa tgccaagaaa gaacctgcat
     5161 tgataccaga ttgtgggctt gcaccatgtg cgcctttacc aactaattcg atttttacat
     5221 acgtattgtc cgcttcaatc gttccgctta ctggatttgc ttcgatgaat tggtaaaatg
     5281 cttcttccat cgcgatagct gcatctgcac ttggtacttg aagtgctgca gttgctgttc
     5341 ctggcaccat attttcgcga agtccggaaa caaaagattt caagacataa tctcctgcat
     5401 tgtcgccttt gaagcgtaaa gctaaagaaa catttccttt ttcaccattg atgattggga
     5461 attcagcatc tggtgagaaa ccaaaatctg gttcttcttc atgttcgaaa taataagcca
     5521 tatcgcccca gccgctttct tcatcgctgc cgactacgaa gcgaactttt tttgatagtt
     5581 tcaagtcaag ttctttaatg atcttcatcg catagtaagc tgccatactt ggacctttgt
     5641 catcgcttga tccgcgtgca aagatctttc catccttgat tactggttca taaggatctg
     5701 tgtcccagcc atctcctgca ggaacgacat ccatgtgtcc aaatatccct agcgtttcgt
     5761 ctccttcgcc aagatcaata tgccctgcat agttatcgac attttttact ttaaatccat
     5821 cacgttcgcc ataagctaac atatgtttca atgcgtcgcg aggtccaggt ccaaatggtg
     5881 catctggtgt tacttttgag tcatcgcgct cgctgttgac acgtaaaaga tttttcaagt
     5941 cttcaagcaa gtcttcttta cgtgcttcta cttctttttg ccaatcaatt gtcataaagt
     6001 taatcctcca cttatttaag tcttcgtgtt catgatacca caaattacag aaaaaaatag
     6061 ttcaaaaaat ctgacaattc cttttcttat ctgtttttct ctaaaaaaaa tatacgctat
     6121 aatgagtaaa aggaggtttt tagatgctga taaacgaaca actagtgaaa agagtcatca
     6181 cacctcgtcc aaaaatttca cataaaggaa catttggacg tatcgttttg attggcggca
     6241 atgaacaata tggcggagca atcattatga gtgctttagc tgccgtacac agcggagcgg
     6301 gtctcacgac tgtagtaact gatgaaaaaa atcggagtgc tcttcacagt catctgccag
     6361 aagcaatgat tgtagtttgg acggatactg accagtttct ttccgtaata aagcaagcag
     6421 atgtactctt gattggtccc ggattgggta cttcttctaa gagtttggaa cgtttcaaac
     6481 aagtactaga aaaccaatca aaagaacaat ggctggtgat tgatggctct gctttaagtt
     6541 tacttgctgc taatcatctt ttgctaccct atcccgaaca aactgtactt acacctcatc
     6601 aaatggagtg gcaacggttg agttctctac cgatacaaga acaacgggat aaagaaaaca
     6661 aaaagaagca acaggaaatc ggtgctgtgc tcgttttgaa aagtcatgag acaaaaattt
     6721 atggtcacca gcacttctac accaatcctt taggttctgc tgctatggca acgggcggca
     6781 tgggtgacac tttagctggg atgatcacag gatttttagc ccagtttcct caaaatgacc
     6841 aaacgattgc agcagctatt tatcttcata gtttcattgg agaccagctg gcaaaagaac
     6901 aatatattgt tttgccgaca caaatcagcg aagcacttcc gaaatggatg aattattttt
     6961 gtaaaaaatc aatggaaaac gaggcatgag tcatggagaa atttacaggt tatgtgcgag
     7021 aaccttttta ttatgaaaca gatcaaatgg ggattattca tcacagcaat tatatccgct
     7081 ggtttgaaga ggctcgggta gccttattgg tacatctagg gtttccctat aaaaaaatcg
     7141 aagaatctgg gatcatcatc cccgttctgg aagtaaattg cagctataaa gaaatgatcc
     7201 attacggaga aaaagtgagc atccatccaa ctatccaaaa gtatacgggg acacggttgg
     7261 attttagcta cgaaattgtg ggaactgaag acaaaaaatt aaaaactact ggcagtagta
     7321 aacactgttt tttactttct gattcgcaac gattagtgaa gctgagcaaa gtcaatccgg
     7381 agttagatca gttattccaa gcgtacgctt ctttggatga tgtaaattct taataaagac
     7441 cgtctaagca tttttcttgt attgtgtcga gtagttcgta taatgaaaag aaaaaagcag
     7501 gtgatcccca tgtatgtcgt taaagtaatg cacggttaca tcgataaaac tggctgtcgc
     7561 actcgggaaa aaaacttaga caatctgctc attttcaaag acaaaaaaga atccgaagct
     7621 tttgctaaaa gaatcggcgg tcgtgtcaaa ccgatccaag aggtacgacc agattgattc
     7681 aatatttttc ttttcgaggc tctaataggc atgcctatca gggctttttt tgcagactgt
     7741 gtttttatgc ccacacgatt tgtaagcgat ttatgttata atagattata tctgcataga
     7801 aaagaaggtt aaatggttat caataatttg caacagcaag cttatgaatc tatacgtaaa
     7861 caaatcattt attccgagtt agcacctgga agtaaaatct ccgataaagt gttagaagaa
     7921 caactagcta tcgggcgtac accgattcga gaagcactga tccaactgcg caatcaagag
     7981 cttgtaaaaa ccattccaca gtccggcact tatgtttcaa aaatcgatat ccgatctgct
     8041 tcattagccc gttatacgcg ggaaaagttg gaaaaaccga tcctgcaaga atgcagtgcg
     8101 aaaatgacca agcaagatca agctaaacta gaaaaaatac tagaacaaac cgatcaggca
     8161 gtaatcgctc aaaataaaaa agcttttttt gatttggata ctgattttca ccgaacttgt
     8221 tatgaaattg ctggaaaacg agaaatttgg gattggctag aaagttatag tacgcacttg
     8281 aaccgtttca gatggttacg tttgacgatt tcagaattag actggggtcg agtattagat
     8341 gaacatcaga caatgcttca atcaatgatt gatcataact ttgatgaagt cggatttctt
     8401 tgcacgatgc atttacatat gattatcgag gagcaagaat acgtgattca taattacccc
     8461 gattattttg aagatattca ggacagaccc atcaaataag aggttttgga atcagcgttt
     8521 tgacctgagt attagagaaa gaaacggcaa aatagttcct catattttgc cgtttttttt
     8581 gagctaatac cgagggtcag ctgattgcac accgtttatt gagaggttgt gaaaaagctg
     8641 ccctgcatca agtaataaga acagccaagt aaaaatagct tcttatgttt ttaacttggc
     8701 tggacttatt accgcagatg caagcttttg aacaccgttt tccaagaggt cgtgagcctg
     8761 ccgttcatct ccgagtcaca aggaacaatt tcaaaaaaca gcttctcatg tttgttgaat
     8821 attttgactt gtgaccgagg agttgacagg agaacatcgt ttattcggaa aaaaaggact
     8881 gtgacacgac ttttgtcaca gtctctttat ttgtaatcta aatcatactc cgtacatctt
     8941 ttttctattt tttttatttc ttctaagatc ccttggctac gaatttcatt atatggccaa
     9001 agtaagactg cctctaatac ataaggcgaa aaatcgcttt gattcatctc ttttgaaaaa
     9061 ctcatcgctg ctatctcgct caatgcacga atgtttgatt gatgtgtata aaaaggcaac
     9121 cgccacagca caattttttc gctttgcgta taaattccct taacagaagc ttcgatgtgg
     9181 tgaaatagtt catgtccaat aatcaaagct tgcgctgttt ctttagagat cgaagctagt
     9241 cctgaacatt ttaatttttc taacggctcc gtcatcaatc gaatcccttc atcttctgca
     9301 taagttgcaa aagtgattcg ttcgtttatt tgctctgatt cacaggaaac gattggaaca
     9361 gccatttgtt cacaaatttc tcctacatcg gcaaaagggt actttttttt gatgctacat
     9421 gccgtttcga taccacaatc gattgattgt tgtataagaa ttttctgctt ggacaaagga
     9481 atctttttcc aaaataaatc tcgccgaaac tggtagaatc cccaaatttc ttcggggatc
     9541 tgttgtaatt cgtttagtaa ctcttctaac ttatgtttgt ttgatatttc cggcaacgac
     9601 gatcacttct tcctccggtt ccatagtaga tacttccaga tccatcaaaa gctgtagttg
     9661 ttccagatcc gtcgctgtaa aatcagagac tcttgctcct aagcagagat aaaattctgg
     9721 tcgggcaatc aattcagttt gataaactgc catatcttcc caaagttgtt cgacagctgt
     9781 catataattg gctgcagttg ttttcataca tgaagcatgt ccacgttgga ccttgataaa
     9841 tcctttttga tcgatgatcc gaagacttcc agcatttttt gaacgattct gttcgccgca
     9901 tacataaaag aaaggtgtat tttccaataa gcaaacttca tttttattta atcgcatatc
     9961 ctctgcagca agctctagtg cttcttctgt tgtgatctcc ttggttagat cggttgcttt
    10021 cacttccgta gaaccagtag cgatagccgt tacttttgaa gtctgtggat cgatttctac
    10081 gtggacttcg atcgattctg gtgtagcgcc tgattcaatc gctttattca tcgcttcatt
    10141 tttcaacgat cgtatatctt ctttacttgg cgaagggatg atacgttcta caacatctcg
    10201 gaccattgca agtgctacac caatagaaga aatcacttcg gcgttttcag gaatcgaata
    10261 tttcacaccc attttattac taaagtaagt aatcaatgag gcagcgccgc cccctacacc
    10321 tacaagagaa atctgatctt tctccaagtg atacttgtct gccaattcta aaatcaccgg
    10381 ttcaatctta gcataggatt tttccatgat ctgttctgcg atgtcttcaa ccgtcgtatg
    10441 acaataatca gctaatgctt ggatggcttt tcgtgcagat gggacatttc cataagaaaa
    10501 atgttcttct tgcactaatc caaggacatt ggctgcacat gtatttgtaa tagtcacttc
    10561 ttctccgtct tccatcacta ccttgacgta atcagcaggg tctccttctt taggagagaa
    10621 aaattcaacc ttaggacctt tgattttttc tgtctccgta aatactgcat aatctagacc
    10681 ggcaatatgt gcagaacgtg gaccgacatc gatgattcct gactgattag cccgtaccat
    10741 cgaaccgcct gccacaccta gaacccgaac atctaatgaa gagatatatg ttgggtggcc
    10801 acctacaatt gaataatcga ttgctggacg tccattttta atgaccccga tattggttgt
    10861 tgttccgcct acttcaaaat aaacaccatt agacgctctc aagtacatca aagagcccat
    10921 gactgatgct gctggaccgg aaagcatggt taaaacaggt cgttttttca tttcattgat
    10981 ttccattact ccgccgtctc cgcgcataat catcaaagaa acattgaccc ctgcttctcg
    11041 tacggaatct tctgtagagg ttgccgtatc tagcattttt ggtaaaatag atgcattgat
    11101 tgctgctgtc cgagttcttc ttgtcaatcc atataatttt gtgatgtcag aagccatcgt
    11161 tgtagggatc gattttaccg atgctgcttc ataaacaact cgttctggtt ccccattatc
    11221 tactccaaat gccatagaag aaaccaagac ctccgctctt tctctttcta aagaagaaat
    11281 cgtttctgaa acacggtcta catttaagtg tttgacaggt aagaatgcat tgacaatctc
    11341 tatttttttc ttattcccta aatcgatatc gttcaatcta gtttgtcgtt ttgctaaaaa
    11401 accttctaat ccaccttttg ccatcccgat tacgccgact tttgctacgt ctccttcaat
    11461 cagtgcatta gtcgcttgtg tggtagaatg tgcaacaaac acaacatctt ctggactgat
    11521 attattttcc agcaaacaat tttgaaaaga ctgaacgaca cctgcggcta ctccacggac
    11581 atcatcgtgg gttgttttca ctgaagattt tccgatgatt tcgtgcgtcg cattatcgat
    11641 tgcgactgct ttcgtatgtg taccgccaac atcaattccc attcgcacaa aacgtttcat
    11701 tttcttttcc tccattcatc taatcgtttt tatcgacgtt ttgtttacta ggcgttcccg
    11761 tacaataaga acgtgatcag gcataagatc gctccgatga tccaaccagt tgggatggat
    11821 ttcttcatat attctcgaga agttactttt gtataaccta atccccaagc aacccaagat
    11881 tgtgtaatat ctaaatgctg aggagcaatc gttgtgattg caaataacgg gaacaaaaag
    11941 gctggcgaca tcgttggatt aacagctaat acgacagcta aaatagctga gcctgaaccg
    12001 actagattca ttggaccgcg gaaaaatcct agtggtgtca atatagcaaa tacgattgcc
    12061 aagactaatg gtgattgcgg tatccaatct ccaaaaatag ctgaaaaata aggagaagca
    12121 tacgcagctg aattattgaa catcgctaag gtcatcaaga aaccaaccat tggcgcaaca
    12181 tctactgcgc catctgtaaa taatttcgca aactgacgac agatttcttt ataacctccg
    12241 cgcaattttc cagtaaacag caatgcccag atacctgcta gaataaaacc taagatgatt
    12301 ggaagatcta aaagaacgac ccctaaaact ggtaataata cggctaacca tgagatcatt
    12361 ggtgcgtcgc caccttcagc tggtacgttt gctgccattg catagcgttt ctttttgttc
    12421 attgatatat tagcgaccgt tagtaccaca actaagctta caatcatccc aatcatacca
    12481 atttggaaat agtcattata agtatagctt tcagccgctg gattgaaacc agcataaatc
    12541 gtttgatatt gtttgaaatt gacgatatta gcaaagattc cagccataat cgagcccata
    12601 aatgagaaca gtgcaaccgg tactgaaata cctaatgaca tcaagattgg caacacaata
    12661 actgcaatag aaatcactgg tccgattcct gtcatcgaca tgaatataac agcggttaca
    12721 atacatagta agctcatcgt gattcttggc ttgtcccctc caagttcaac tacctttcga
    12781 atcagggtag ctgcgattcc gctatctact agaacacgcc cgaaaaaggc accaaagaag
    12841 acatttacca agatcgattt ggcgtactca gctggccccg tcgtatagat atgcgtcaac
    12901 acatcaatta ctccttgccc ttccatcgcc gggtttggtg aaaacgtgtt tccgactagc
    12961 gctaatccca tccatacagt agccatgatg gcaaagccga ccatcaagtt gtagcctttt
    13021 acacagtacc agaccatgaa aaagaatgag ataactaaca aaataccaat aataatatca
    13081 ctcatgttat tcctccgtcc attttgtttt tctgataagc aaactaatat atcagtcaaa
    13141 ctcattctaa cttatgtagt tagcgctttc attaaagggt gaccataaat tgttcagttt
    13201 tcaattaaaa aaccttaatt atgctatttt agacttatac gttattgtcc tgtttcattt
    13261 gatggaggat tgtaaataaa aaaagaggaa agaacataac ttttcgttat cttctttcct
    13321 ctttataatt gtttagctta tttagccaaa gcttcttttg cttggtcagc caatgcagta
    13381 aatgctgctg catcgttaac agccaagtca gctaacattt tacggttgat gtcgatttca
    13441 gcaactttca aaccgtgcat taattttgag tagctcaagc cattcatacg agctgctgcg
    13501 ttgatacgag caatccacaa tttacggaag tcgcgtttct tttgacgacg atcgcgatat
    13561 gcgtagttgt atgaattcat tacttgttct tttgctgttt taaataaagt gtgttttgaa
    13621 ccgtagtaac cttttgctaa ttttagcact cttttacgac gtttacgagt tactgttcca
    13681 cctttaacac gtgccatgta taattcctcc taataaaaat aaatcttcag attctgttat
    13741 ttgtacttct tatttcattt ttgctagttg ttggcgaata cgtttgaagt cgccactaga
    13801 aaccatgctt gctttacgca attgacggcg ttgttttttt gttttgccgt ggaaacggtg
    13861 acttgtaaac gcgcggaagc gtttcaatcc gcctttacca gtacgtttga aacgttttgc
    13921 tgatccgcgg tgtgtttttt gttttggcat gactatattt cctcctcaaa atctttcgtt
    13981 atccgactat cggctgtcca acagccagtt agtcattcaa attacttact gtcgtttttc
    14041 ggtgccagcg tcaagaacat gctgcgtccg tccattttcg ctttttgttc cactgttgca
    14101 atatccgcag tttcttcagc taagcgattc aagacttttt gaccaatttc tttatgggta
    14161 atggcacggc ctttgaaacg gatagaagct ttcactttat cgcccttttc caagaactta
    14221 cgtgcattac gaagttttgt attgaagtca ttcaagtcga tcgtaggact taagcgaact
    14281 tcttttacat tgatcacttt ttgtttttta cgcgcttcgc ggtctttctt ttgttgttcg
    14341 aaacggtatt taccgtagtc catgattcgc gcaactggtg gtttcgcacc aggggcaact
    14401 aacacaagat ccaagtttgc ttgttctgca atattcaatg cttctgcttt tgtcttaact
    14461 cctaattgct caccatctga accgatcaat cgtaactctc gtgcacgaat gccgtcgtta
    14521 accatcatat cctttgctat ggtcattcac ctccaaatat tatgagagaa agaaaagctt
    14581 accgaataaa cggcaataaa aaaacgagtt ctcttacaga acccgcgcgt acttcaccta
    14641 atagaaccag tgaaaactat ctagcccagt gacattatca actaaggcga gaagcgggtg
    14701 cttctgcttt tatttctcaa ccatcatagt atagcaaaaa ctaatctttt tgtcaatgtt
    14761 tttcatacag tttgtcttcc ttttctgaaa atgattagat tagcagactt tctagcagtg
    14821 attcccgctt ctttgctata ctaaagaaaa acgaggtgaa cccacatgaa aaaaatcgaa
    14881 cctattccac cttctcttcc tcttcttaca aagggagagt tttatttaga agatgaggag
    14941 atcttctctg gtcttctgat caacgggggt gaccaaagct atctcgatgc caaaaatatg
    15001 gtattaagag agagtcatat ccaaaaactt acgatgcaaa aaacagtttt acgtcatttt
    15061 gaatgcagta atgtcatttt tgaaaaatgt gatttttcca atctggagtg gattggtggc
    15121 agtttccacc aagtcgtgtt tcatcaatgt aaattaacag gtacgaattt tgccgaaagt
    15181 tatcttcgag actgtacttt cactgattgt attgcttcga tggcttcctt tagtagtaca
    15241 aacttgaaag ctgtctcctt cgatcattgt caattagaag acagcgaatt ttatgaggtc
    15301 acttggaaaa accttttttt gtctgacaat cagttgaccg gttcgaactg gtttcgaact
    15361 tctctgaagg gattagactt tacgactaat ttcttcacag caatcgcttt atctcaagat
    15421 tctttggcgg gactaatcgt caaccaagag caagcacttg tgatcgccca agcccttggt
    15481 ttgcagatca aagactagat caacgaatcc gccgccacag tgcaataagc atccaaatag
    15541 ataagaccaa actgatgatc aaggcgattc cccatccgaa aacggaatgg gtaaagggta
    15601 actggagatt cattccgaag aatcctgtca caatagttgg aacggtcaag atcagcgacc
    15661 agaccgtcaa aaatttcatc gtgtcattca agttgttatt cagcaaatta ttataagtgc
    15721 cagagagctg gtctaaaatc tgcgaagcta agttcgtcat ttcaactgct tgtcgtgctt
    15781 cgatcagcgc atcgtccaac tcttcttttt ccttttctga caacttgcga taaatagcca
    15841 atgccttgat ttgttctaaa agtactacat tttgttttgt tcctgtaact aagtaaacca
    15901 aaccgatctc taaatctgaa agttgcagca gattcttgtt cgttgttttt tctcttaatt
    15961 tcagattaag ccgctgacgt tcactattca cttcctcgat taaaggaaaa aaggaatcag
    16021 aaatcaaaaa caatgtacga aacaataaac tgtatacact catgtctggc attcgttcca
    16081 aaagcgatcg aattagtcga atcacgtact cggtattcgg cgtggtaaat gtaaacaaac
    16141 cgtcttcttt taaaataaaa gcgataggac tagtttcata atgattatcg actttttgct
    16201 ggtgcggaac atttgataca agcagtaacg cttcatcaaa agaatcgtac tctacgcgcg
    16261 cccgttcatt tttatctaga gaataagtca gcatctcgtc actaatgcca tattcttctt
    16321 ttaagttttt aacagctagc acatcgtttt gctgtacatt gatccaaaaa ttacggtctt
    16381 gattaaaata gtgtttttcc cgcatactct atcctcctga catttgtttc cagtataaag
    16441 aaaaaagtcg ctcaaataaa ggtttaccct ttatttgagc aactgtaaat caaatggcta
    16501 ctttggtttg gcgaatctct gctaattttt cttcgatcat tttcaagact tcttcttttg
    16561 cttgaggatc ttccacaaaa ttatagcggt ctccatcgat ttggattttt ggactttctt
    16621 tgtattcttc ataccattga tcgtaacgtc tgttcaattc tttgtaataa tcgtatagac
    16681 ttggatcaaa ggacaattgt tcatacgaac gaccacgttt ttcgatacgc tccaacatcg
    16741 tatcaaaaga tacacgaata tgaactaata aatccggatg ttttttatgg gcagcatagg
    16801 gaagttcttc catcatgttt tccagcagtt catcatacac acgaacttct gtttctgttg
    16861 ctcttcctag atctgcattt agatggaaaa gcagtgaatc ttcataaatc gaacggtcca
    16921 atacattatt gtcatctttc attgcttgtt tgatgcttgc aaaacgttta ttcaaaaaat
    16981 aaatttgcag caaaaaagca tactgttcag ggtttgcata aaataagggc aagacttcat
    17041 tatcatcaat cgattcataa aatgcctgac tatcaaagtg ttcagccatc atttctgtta
    17101 aacttgattt tccggcacca attgtacctg ctaaaacgat cacgctcatt tacctccagc
    17161 tcacttcatc actaaatatt gtgtttaact ccaacctttt taaatatacc cccaatatct
    17221 agtagtgtca attgtatttt tttctagtca aagaagaaaa aaagtcaaaa aattcttaag
    17281 aaaaaagtgt tttttcttta gaaaacgtat tcttagtttt acttctgaga tggttttagt
    17341 aaaataaagg aggaatgttt tttgagaccc ttagtggaca aaaaaattcg tgaagcagcg
    17401 caactcgttt tgggcgcttt attttttgct taaaaatcac ttttacgtga gaaggagtta
    17461 gattatggca aactatggcc aaggagaatc aagcggaaag atcatattga tgggcgagca
    17521 cgcggttgtt tatggagaac cagcgattgc ctttcctttc tatgcaacaa aagtcaccgc
    17581 attccttgaa gagctggatg caatggacga tcaactggtt tcttcctact attcaggaaa
    17641 tttagccgaa gctcctcatg cattaaaaaa tatcaaaaaa ttattcattc acttaaaaaa
    17701 acagcatgac atccaaaaaa acttgcaact gaccattgaa agcacgattc ctgctgaacg
    17761 tggaatggga tcaagcgctg cagtcgccac agcagtcact cgtgcttttt atgattactt
    17821 agcatttcct ttgtctcgtg aaatactatt agaaaatgtc cagctttcgg aaaaaatcgc
    17881 ccatggtaat cctagtggaa tcgatgcagc cgctactagc agcttgcagc cgatttattt
    17941 tacaaaaggg catcctttcg actacttttc tttgaacatc gatgcttttt tgattgtcgc
    18001 tgatacagga atcaaaggac aaacaagaga agccgtcaaa gatgtcgctc acctctttga
    18061 aacccagcct catgaaactg gacaaatgat ccaaaaatta ggatacttga cgaagcaagc
    18121 aaaacaagca atcattgaaa attcaccaga aacgttggca cagacaatgg atgaatcaca
    18181 atcacttctg gaaaagctga caatcagcaa tgattttctt aatctattga tccaaacagc
    18241 aaaagatacc ggggcattgg gtgccaaatt aactggcggt ggacgcggtg gctgtatgat
    18301 tgcattagca caaacaaaaa caaaagccca agaaatcagt caagcacttg aagatgcggg
    18361 tgctgctgaa acttggatac aaggattagg agtacatacc tatgtttaaa ggcaaagcac
    18421 gcgcatatac caacattgct ctaatcaaat attggggtaa gaaaaatgaa gaactcatcc
    18481 ttccaatgaa caacagcctt tcgttaacat tggatgcatt ttatacagag acagaagtca
    18541 tcttttctga tagctatatg gtagatgaat tttatctaga tggcaccttg caagacgaaa
    18601 aagcaacaaa aaaagtcagt cagtttcttg acctttttcg taaagaagcc ggcctctcac
    18661 taaaagcttc agtaatcagt cagaatttcg ttcctaccgc agctggatta gcctcctctg
    18721 ccagcgggct agctgcttta gcaggcgctt gcaatactgc tcttaagctt ggattagatg
    18781 atctctctct ttcaagattt gctcgacgcg ggtctggttc agcttgccga agtattttcg
    18841 gtggtttcgt cgaatgggaa aaaggccatg acgacttaag ttcttacgct aagccagtcc
    18901 cttccgattc tttcgaagac gatttagcaa tggttttcgt tttgatcaac gaccagaaaa
    18961 aagaagtgtc cagcagaaat gggatgcgtc ggacagtcga aacatccagt ttttatcaag
    19021 gctggttaga ttccgttgaa ggggatctat atcaattgaa acaagcaatc aaaacaaaag
    19081 atttccaact tctcggagaa acgatggaaa gaaacggact aaaaatgcat ggaacgactt
    19141 tagctgccca gcctccattc acttactggt ctcctgacag cttaaaagcg atggatgcgg
    19201 tgcgacaatt gagaaagcaa ggcattccat gctactttac gatggatgct ggccctaatg
    19261 tcaaagtttt agtggaaaac agccatttat ctgaggtaca agaaacattt accaaattat
    19321 ttagcaaaga acaagtaatt actgcacatg ctggtccagg aattgcgatt attgaataaa
    19381 gggagatttt tatgattgaa gtatctgcac caggcaaact ctatattgcc ggagaatatg
    19441 cagttgttga aacaggccat ccagcagtta tcgctgcagt cgatcaattc gtgacagtca
    19501 ctgtagaatc tgcacgaaaa gtcggaagta tccaatctgc acaatatagt gggatgcctg
    19561 tacgttggac aagacgcaac ggagaattag ttttagatat tcgggaaaat ccttttcatt
    19621 atatccttgc tgctattcgc ttgactgaaa agtatgcaca agaaaaaaac attcttttat
    19681 ccttttatga tctgaaagta acaagtgagt tagacagttc aaatggccgg aaatatggat
    19741 tgggttctag cggtgccgtg accgttgcaa cggtcaaagc cttgaatgtt ttttacgcgt
    19801 tgaatttatc tcagttggag attttcaaga ttgcagcact agccaattta gcagttcaag
    19861 ataatggttc ctgcggcgac atcgctgcta gctgttatgg tggctggatc gctttctcaa
    19921 ccttcgacca tccttggctc caagaacaag aaactcagca ttctatcagt gagttacttg
    19981 ccctggattg gccaggtcta tccattgagc cattgattgc tcctgaagat ttacgtttat
    20041 tgattggttg gacgggtagc cctgcctcta cttctgattt ggtcgatcaa gttcaccgtt
    20101 cgagagaaga taaaatggtg gcttatcagc ttttcttaaa aaatagtaca gaatgtgtca
    20161 acgaaatgat caaagggttt aaagaaaata atgtaacgtt gatccaacag atgattcgaa
    20221 aaaaccgaca attactgcat gatttatctg caatcactgg ggtcgtcatc gaaacgcctg
    20281 ctttgaacaa attgtgtaat ttagctgaac agtatgaagg agccgcaaaa tcttctggtg
    20341 caggtggggg cgattgcgga atcgtaattg ttgaccagaa atctggcatt cttcctttaa
    20401 tgagtgcatg ggaaaaagca gaaatcactc cactgccgtt acatgtctat agcgatcaaa
    20461 gaaaggaaaa ccgatgaatc gaaaagacga acatgtttca ctagctaaag cctttcatga
    20521 taaacaaaaa aacgaatttg acttcgtacg gatcatccat aaccctttgc cgcaaatagc
    20581 agtttctgat gtcgatctaa gtacacaggc agttgggttt acactaagca gcccatttta
    20641 tatcaatgcg atgactggcg gaagcgaaaa aacaaaaaaa atcaaccaag atcttgcaat
    20701 cgtcgcaaga gaagcagatt tgatgattgc cactggttca gtcagcgctg ccttgaaagt
    20761 cccttcttta gccgatactt atacgattat gcgacaagaa tatcctcacg ggaaaatcat
    20821 tgccaacatc ggtgcaggga cttctgtcga aagagccaaa gaagctatcc gattgtttca
    20881 cgcagatgcc ttacagattc atttgaatgc acctcaagag ttggttatgc ctgagggaga
    20941 ccgtgatttt accaattgga aagtacttat tcaagaaact caaacagcca ttgacgtccc
    21001 cctcatcgta aaagaagtcg gttttggcat gacaagagaa acgctcaatg atctagctgc
    21061 tttaggagtt catacagttg atatcagcgg tcgaagcgga acaagcttca cccagatcga
    21121 aaacgcccgt cgctccaagc gggaactgag ttatttagct gactgggggc aatcgacagt
    21181 ctcttcattg cttgaagcaa atgaagcaga cacttctatg gaaatcctag cctccggagg
    21241 tatccgcaat gcctatgaca tatttaaagc cctttgtctc ggcgcaaatg ccgtgggtac
    21301 ttcaggaacc gtactgacgc atctgatgaa tcacggcgta gaagaaacta ttatactgat
    21361 gaagcaatgg caagaagagc ttcgtctgct ttatactatg gtcggcgcaa cgaataccgc
    21421 ggccctacac caacaatctc tgatcttttc cggaccagtg aaggattggt gcgaagcaag
    21481 agggatcgac ttagtgaagt atggaagacg cacagaaaag agcgtgggac aaaagtaaag
    21541 aacacttttg tctcacgctc taaacacgta caaacggcgg aagtaaaagc aactccttcg
    21601 gaaataagct gaaattcaca aaaatttgaa aagcaatttt cgtgaattcc ttcttatttc
    21661 ttggagttaa atgcttctgt cccagcctct tttttcgaat aaatgatgtt taatcagctg
    21721 tccttcggta ttcgttcaat ccgctgattt cacaacctct ccactaaaca gtgtactaaa
    21781 gctcttttaa ggttgttttc cgatataggc aagtatgcct ccgtccacat acaagacatg
    21841 gccgttaacg aaatcagatg cgctagaagc caagaagaca gatggtccag ccaaatcgat
    21901 tggctcgccc cagcgtgctg ctggcgtacg tccaacgata aattgatcga atggatgacg
    21961 ttcaccgttt tcttgtgttt cgcgtaatgg agcagtttgc ggtgtagcaa tataacctgg
    22021 tccaattcca ttacattgga tattgtattg accgtattca gaagcgatgt ttttcgtcag
    22081 catttttaat ccgccttttg ccgcagcata agcactgacc gtttcgcgtc ctaattcact
    22141 catcatggag cagatattga tgattttacc gccgcctttt tcgatcatat ccggaataac
    22201 tgcttttgaa acgatgaatg gggcatttaa atccacgtcg attacttggc ggaagtctgc
    22261 cgcatccatt tcgatcatcg gtgtccgttt gatgatccct gcattgttga ctagaatatc
    22321 aactgaacct acatcttctt tgatctgttg aaccatcgct tgaaccgctt cttcatcggt
    22381 cacatcgcag acataacctt ttgcatcgat gcctgcttct ttataatgcg ctataccttc
    22441 atcaactgat tcttgattca agttattaaa tacgattttt gctcctgctg tagctaaaga
    22501 gcgtgcaatc tcaaatccaa taccatagac agcaccggtg actaatgcta cttttccatc
    22561 taaacgaaac atatccatac taaattccat cattttctct cccttatgct tattttaatt
    22621 gatccatttg caccatatcc atgtctgtat aggtgatatt ttctccgcac attgcccaga
    22681 tgaatgagta attgcttgta cctacacctg aatggatcga ccagcttggc gaaataatgg
    22741 cttgttcatt gtctacaact aaatgttttg tttcatctgg tttgcccatc atgtggaaca
    22801 cacgtgtatc ttcattggca taatcaaagt agacataagc ttccatacga cgttcatgtg
    22861 tatgacaagg catcgtattc caagcgcttc ctggttctaa aatcgtataa cccatttgta
    22921 attgacagct ttcgcataca tttggatgga tgtattggta gattttacgt tcattcagtg
    22981 tcaggccttc accagtctcc attggtttta cttggtcgat actgattttt acatttggat
    23041 atttatgatg agctggaaca gaactaatat agaatttagc tgggttttca gcatcttgag
    23101 aagaaaatac aacatgtcgt gtttcttttc cgatatagta tccgtcttgt tttttcattt
    23161 cttctttttg cccatcgatc tcgatgaatc ctggtccacc gatattgatc acacctagtt
    23221 cacgacgctc taagaagtaa tcaacaccta gttctttgtc taatgtgatt tctaattctt
    23281 tttcagtagg tgtcactcca ccaaagatca ttcgatcgtt gtgcgtataa gtcaaactga
    23341 ttttccctgg ttcaaatacc ttttctacta aaaattcttt tctcaattgt tccgttgaat
    23401 aatgacggat atcttctgga ctgtgtgtat aacgtgtttc catttcttgc attttcttct
    23461 actccttcta tcgaatgatt tttccagagc cgcatgctaa aaattgtgcg acttcttctt
    23521 gactaaattg gttgcagtcc ccatggatcg tatgcttcaa ggcagaagct gccgtagcaa
    23581 aatcaatgat ttcttgcgga gacatattgg ataaaatccc atggagcacg ccacctgcaa
    23641 aagcatctcc gccacctact cgatccacga ttggggtgat tctatggact tgggattcca
    23701 catattcatg gttcatccac aatgtcccct tcaattcatt ttcacttgct gaatgaacgg
    23761 tacgcttggt cgaataaaac acctgaatat tcgggaactt ttcctgcatt ttttgataat
    23821 aataaattag aggttgttct tctgcttctg gcgctttctc gatacctaac aaataaagag
    23881 catccatttt tccagctgag cagatatcta ctaaaggtaa aagctgatgg attacttcgc
    23941 tggcttcttg ctgtgtccat aattttccac gatagttgat atcgaagctg atcaggcagc
    24001 cagctttttt tgcagcttct atcacctgtt tcgtcatttt ttgccatttt ttagacaaag
    24061 ctggggtgat tcctgaaaca tgaaatatat ctattccttg gaataactcc tctagcgacc
    24121 attccaaatg atccatttca gcaaaacttg atccggcacg atcatagatc actgaggcgg
    24181 cgcgttcgcc actaccagtt tccatataat aagtacctag tcttgatcca ccagataata
    24241 cctgtttcgt atctactcca taacattgca agtgcttttt gactgctttt cccaatgcgt
    24301 tatcaggtac ttttgtagca aaaatcgctt catgtccgta attagctaaa gaaattgcta
    24361 cgtttgcttc ccctccgcca taatgggcag cgaatcgttc acttgaatcg atacgggttc
    24421 cctgctctgt ggacaatcgc aacatgattt ctccgagtgt cactactttt cccataagca
    24481 gctacctctt gatttctttc atttttgctg catactgttg cgcgacttcc gttactttgt
    24541 caaaatctcc tgtagctgcg ggtgctaaaa ggttcccacc tactccgact gttacgacac
    24601 cagcatcgaa ccactctttc atattgtcca gactcacacc gccagttggc atgatattga
    24661 cttgaggcat cggcgccttg aaggcagaaa tgatacttgg tccataagcg cttccaggaa
    24721 atagtttgac gatatctacc ccgcttttca gcgctgtttt gatctcggta atagtcatac
    24781 atcctggtaa gtaaggaatt tgatacagat tgcacatctc tgccgtttct tgatcaaagg
    24841 aagggctaac aatatactct gcgccagcta agatagccaa gcgagctgtg acagcgtcta
    24901 atactgtgcc tgcgccaatc actatttctg gttggtcttt gtagaatgac aaaagttctt
    24961 tgattacttg atctgcttga gggactgtaa aagtcaactc aataccagtt agaccacctt
    25021 tgatgattgc gtggcaagca ttcaaagctt cttctttgct ttttccgcgt accaccgcaa
    25081 tcactccggc gtttttcaat cgagataaaa tatcaatttt tttcatcttc tccacctatt
    25141 tcctatttag aaattttatt ttataacttg gaaatctata cccatattat acggcagaaa
    25201 agaaaaattg caaacgcttt tttcattatt tttgaattct ttgctcgatt tcgctttttg
    25261 tttgcttgag ggcactgatt atttgttctt ttgtctcatc tgttaaacga tatttcggca
    25321 tacttacact aaatgcacca atgatttgtt cgtttttcac gattgaggct cctatacaaa
    25381 aaatatcacg ttcgatttct tcatcgtcaa atgcgatgtg ggtttctttt accgttttga
    25441 tttccttttt caaccgtaat gcattggtga tcgtatattc tgtgtaaggg atcaacggat
    25501 gcttttcaag ataatcagtg tactgctctt cactgaattc tgctaatacg gctttgccca
    25561 tcgcagaatt gtataatggt cgggtgattc cgatttttga agacatgcgg atcgtttgat
    25621 gttttggatc tagtttgttc acgtacaaga tctcattgtt gtccaatacc cctaagtgga
    25681 tagtctcatc gatcttttgc tgcagctgtt ctaaaaacgg taaagtcaac tctaccaaat
    25741 cgatttgttc aatgttttta ttcgcgtagc gaataagctt tgcacctaaa cgatagtttt
    25801 tctctgaatt tttatttacg tagccgatca tcaacaaagt atctagtatt ttcaagactg
    25861 tagaagaggt cattcccaca ccctttgcga tcgtctgcaa agagacatct tggttttccg
    25921 ctaaatagtc tagtatttta gaggctttga tcaatacagt tccataaggc tttttatttt
    25981 ccatataata ttctcctatt tctttataag aaaaattata gcggaaatac catcaattta
    26041 aaagagatat ccagatataa actaccattt ctctttacag gcaatttaat gttgaagatc
    26101 cgcttcgttt ttacatcaaa ctttgatata aagcaatgat ttcttctact gtcgtttctc
    26161 ttggatttcc tggtgtgcat acatctcgca aagcatcttc tgcaattgct ggaatatctg
    26221 cttcttttac acctaattca gaaatggttt ctgggattcc aaccgctttg ctcaaccgat
    26281 cgatctcacc acaagccgct tctcttacat cttctaaaga catttcagct gctcctttaa
    26341 tccctagaac aagagcgatc tcacggtact tttctccagt atattctttg ttatatttca
    26401 tgacagttgg caaaagtgct gcacacgcta cgccatgagg aatgttgtac catgcactta
    26461 acgggtgagc catcccgtgt accagtccta aaccgacatt tgagaagccc attcccgcaa
    26521 tatactgtcc taatgccatt ttttctcgcc cattttgatc gccatctaca gaagcttcca
    26581 aagaatggcc gatgatttcg attgctttta aatgcagcat atcagtcatt tcccaagcgc
    26641 cttttgtgat aaacccttca atagcatgcg tcatagcatc catacctgtt gatgcagcca
    26701 attttttcgg cattcccatc atcatatcgc tgtcgatgaa cgcgacgatt gggatatcat
    26761 gaggatcaac acaaacaaat tttcggtgat ttacttcatc tgtgatgacg tagttgatcg
    26821 ttacttctgc tgctgttcca gaagtcgttg gtatagctaa tataggtaaa catggatttt
    26881 tcgtatcagc aacaccttct aaactaatga cgtctgaaaa ctctggattc gtcaaaataa
    26941 tcccaatggc ttttgccgta tcgattggcg aacctccacc gattgcgatc aaacagtctg
    27001 cctctgcctc tttaacaaaa gccactccat cttttacatt ttggatcgtt ggattaggta
    27061 cgatcccgtc gtataaagca taagcgattg ctgctttatc tagaagttct gttacttttg
    27121 ttgctatacc gtgctcgatc aatcctttgt cagtaatgac agctgctttg ccgaatcctc
    27181 gctgctgaaa ttcagggacg atcgactcaa tcgctccttt tccaaaatac gatgtttcat
    27241 ttaaaatcat tcgattactc attttctatt cctcctaatt tgtattattt ttcacaataa
    27301 aaacgaaaga accccaagca accggttgcc cagttgcttg ttgctacagt tcaaagactg
    27361 gcatcaattc ccaactgact ggagaggcat ctggatttgt ctccatgata tcttccatgt
    27421 acttccacca tttttgattg atagatgtat ttgccatttt ttcccataac ttttcatctt
    27481 cgatcactaa gtaaccaaat aacaaacttg tactcggatc aagatagatc gaatagtcga
    27541 tgaccccgtg ttcacgaagt gctgtacgca tttctggcca aagttcatca tgtctttttt
    27601 tgtattcttc ttgtttttct gggtaaactt tcatgcaaaa agcttttttc accatgtcag
    27661 acacctgctt tcgtatgaac ttcctccaaa taacctgctt ttggagtgac accaaacgca
    27721 tctgctaaat gccacaggtt ttcgtccgtg attgtttgca agattggtcc ttgcgctttg
    27781 acgtacgtat agacttctgc tgccttttct gctgtctcga tcaaaccaaa gacttcatcc
    27841 atgtcttttc ctgacccgta gattccatgt tgtggccata aaaccaatcg agtttctttc
    27901 attttttcag ctgttgcttc cccaatctca tttgttcccg gaaccatcca cggaatgatg
    27961 gaaattcctt ctggaaaaac aactaagcat tccgtacaca tttgccatag cgtacgacta
    28021 aaggaacgtt cgtctaattc atgcgtaaaa ctcatcgcta atagatgact agcatggcaa
    28081 tgcataacga tccgattatc tgggtctact tctaaacggg cgatatgact catgaaatga
    28141 cttggcaact cgcttgtagg aaggcattcg ttttccagcc cccacaaaag ttccagtgtt
    28201 ttgccatctt cagcaactcg aacgattcca agattctcgg caggttcgct cgctacattt
    28261 ttaaaatatc ttcctgaacc agttacaata aaatagcatc ctgctaaacg gctggcatca
    28321 aaaatcatcg agatgcggcg gatcactttt tcaggatcca agaacggtgt gatctcttct
    28381 tcttttagta aataagaaat attcccgcca tttctttcat cccatcccaa gcgataaaga
    28441 ttcgacgtcg tttcgatcat ttctttcaca taaggcgctt gtaaaatatc tatttttttc
    28501 aatatagcca cactcctatt ttcttaattc caacacgtct ttttgatatt cctggacttc
    28561 ttccagccaa tccaaaccaa ctggaacttg atttttgtaa cagaaataat tccatacatc
    28621 ggcatacggg aaatctttca attcttccgt ataagccatt cttgaagtaa agtcaaaagc
    28681 cagctccatt tctttcaatc gctcaactgg ttccagcata gctttcagca gtgctttttg
    28741 tgtatttctc gtaccgatga cccaagcagc gatacggttg atcgttgcat caaagaaatc
    28801 cagaccgata tttgtttttt ccaacaattc gttacggact aattctttag cgatttcctg
    28861 caattcatca tccatcaaaa ccacatggtc tgaatcccaa cgcactggac gggaaacatg
    28921 caacatgatt cctttgctga ataaagctaa tgaagataat ttattggaaa tcacttctgt
    28981 tggatgaaaa tgtccagcat ctagacaaac aagtttgtca cgagtcaacc cgtaacccat
    29041 ataaaattca tgggaaccga ctgtataagc ttcagcgcct aaaccaaata gtttgctttc
    29101 tactgcatct tgtacatacc gttcatctaa ctcttctgta aaaatttcat cgagtgattc
    29161 cattaaacgt tcccgtgggg taaaacgatc aatcggatta tctttcatcc catcaggtac
    29221 ccaaaagtta ttgatacttg tttgcccagt ttctttccca aagtactccg cgattttgcg
    29281 gcttcttttc ccgtgttcga tccagtattc acgaacttct ttatctggat gagccaatgt
    29341 aaagccgtct ttcatcattg gatgcgaaaa gaaagtcgga ttgaagtcaa gaccgatttc
    29401 ttcttttttt gcccactcta cccatttttc aaaatgtttc ggctcaattt catttagatc
    29461 gacagattct tctgtatcca aatagatagc atgaaggttc aatttgtgtt tgcccggtat
    29521 caacgaataa gccttctcca gatcttgtct aagctcttca ggtgttcgtg cggctcctgg
    29581 aaaattccct gtcgccatga ttccaccggt caattcgcca tccggtgtca agaaaccttt
    29641 gacatcatct ccttgccagc aatgcataga aattttgatg tcctgtatct tttctagtac
    29701 agcatctgta tctacaccga tagttgcata tttttctttt gcttgttcgt aatttctttc
    29761 aatcgtgttc atacgattac tcctttgatt ttattcacgt accattccat cgtgttttgc
    29821 ttattttcat ctgggtaaaa agtttcacat ggaaacgact gtttgattac atttcttgct
    29881 tgttctatat tcgaaaactg acctgtactg agcatttgca tggcaacatt cccgattgct
    29941 gtggcttcac taggtcctgc ttctacaatg attccggcat aatctgctgt caattgattc
    30001 agtagacgat tattcgatcc gccccctacg atgtgcagct tttccaattt cgttccagtt
    30061 aagtgttcta ctttgatcag ctcttgtgcg taacaaagag caagattatc atacacacaa
    30121 cgagcgatag ctcccgatga gacagggact ggctgctctg tttcaaaaca gtattgctga
    30181 atctcttcta tcatatttgg gggattcaaa aatcgagggt cattgatttc catcacttgc
    30241 tgcagcggtt tttcttttgc agcaagctct gccaattccg cataactgta ctcgtactct
    30301 tgcattcggg caacttcctg gatcaaccac atccccatga tgtttttcaa aaaacgcacc
    30361 gtgttatggg caccccattc attcgtataa ttttcagaaa aagcattgcg agaaacattg
    30421 gcgatctttg tttcaatccc taaaagcgac catgtcccac tgctgatata accccaacgt
    30481 tctccttgac ctggcgttcc taatacagct gacgccgtat catgacttgc tactgtgata
    30541 aaggtcacat ctggcaaatc atattttgaa aattgttctt tttgcagatc tcctagtatc
    30601 gttcccggct ctgtcaatgg tggaaataat tccttcgaga caccgatttt ttcaagaagt
    30661 tctatttccc attcttttgt ccctgcattc agcagctgca tagtagatgc attagttttc
    30721 tccgtcacca tgttaccagt aaagacatac cctaaataat caggtatcag taacaattta
    30781 tgtgcttttg ccaaattttc tttttcttca gcaaacaatt ggaacaaggt attgaaaggc
    30841 tggatctgaa tccctgtctg ctcatacaac ttatctagag aatagatttc agaaaactgt
    30901 tctactgctc cattggtacg cttgtcccga taagcaatcg gatcatttat ccgatcccct
    30961 tgttcatcaa tcagacagta atcgactgcc catgtatcga tccccgcaaa aaggcgatca
    31021 atccctgtct gctttaattt ttcaaatcca atcaaaatct ctttgataag ataatcgatc
    31081 ttccagcgat cgtgaccgtc tttgttccga aagccgtttt tgaaccggtg tacttcttcc
    31141 aagatcaaag aaccttttgc atccctcgta cttttcatta gtcgtccgct tgatgcaccg
    31201 atatcgatgg caacaaatgt tggattcatt tctccacctc ttttacttta ttgttgatta
    31261 gcactttatt aataaagcgt tatcatttat tgacaatgct atcataatac agaatcttat
    31321 attttgcttc acactatttt ggtatataat tgcattatct tgacaagttg ggagtgttta
    31381 catggattac tgggaaaaag ccaaccactc atggtcggaa gactcaaaaa gagtgatctt
    31441 gacgcctaca caaagaagca ggaatttatt tttttatatc caagaaatcg gttacttcaa
    31501 agcaccaatc ccttactata ctgaacgagc acatttacct tcttacttga taaagtttac
    31561 tttgtctggc aaaggttcgc ttacatataa tgataatcag caacagctaa aagctggaga
    31621 cttatttttt attgactgcc aagaatatca gcgttatcaa acgatcagcg aagaaccatg
    31681 ggaaatggat tggatccatt tgaatggtca gaacgtccaa tcattttatc aggagttcac
    31741 aaaagacggc cataacacct tccattcaac aggagatcca tcagaaaaca agatccacca
    31801 tttgatcaca gaattgatcc acatgcaaca aggcacgaat gcccgtaccg atttccagtc
    31861 ctctgtagct atccacgagt tgctgaatga actgattttg caaaagtatc agctagattt
    31921 cgaagaagag gatattcccg cctacgttta caaactgaag caatacttag acgaacattt
    31981 caaagaaacg attacacttg atcaattaga acaacaattc ttattgaata aatatcagct
    32041 gagcaaagat ttttccaaat ttatcggttc tccaccaatc gattatttga tcagcaaaaa
    32101 actttcttac gctaaagacc ttcttcggta tacagaattt acggttcgaa tgatttccga
    32161 agaaataggg attgagaatt ttgcttactt tagccgcctg ttcaaagcaa aaacaggact
    32221 atcgccgaga gactttcgta aattcagctg attcatataa tatgtacgtc attttttcaa
    32281 aatattttga aatatataga taaaaataaa ataaccgcag tttctgcttc tatgtaaaca
    32341 acagcagcta ctgcggttat tttttagtga tcattctcat tgttcatctt caaaatgttc
    32401 ataatgaacc aactgtttct gtgtatcacg tttcaaaaat tctttaggcg ttatgccgaa
    32461 ctctctcttg aatgctttca gaaaatgcgg ataagaagaa aaaccacttt tactatatac
    32521 agcactagag ctgcggtatt ctcgcaacaa gtgcttggca tagatcagct ttttcttcat
    32581 tacatactga tgaaacgtaa atccagtgta ctttttaaat tctcgtgtga tatggtattt
    32641 gctgacaaaa aactgctttt ccatttcctc taaagaaagc ggatgagata aattttttga
    32701 gatatattgt aacatttgtt ccacacgctc attaggaact acagcattct gttcttgcgc
    32761 actctcttct ttttgtacaa cttgattgag aaaaatcaag tattctacca gagcttgttc
    32821 atattttatg tcttcaccgt aaattttttt atcaggagga tggtcgataa atgataattt
    32881 ttgcttcaat acttcctgtt ctatttgcaa tacacgactc ctcttctctc ccattggttg
    32941 aaaacaagcc gatagattag accatggcgt ggaacgactt tctagaaaag aaggggtgac
    33001 aaagatatag acacgctcga atacatctga agattggcgg acgatacgat gcaaatcatt
    33061 ggaatggatg agcagcacac ttcctgcttt gatcgtaaat tgtcgtccgt tcaaataaaa
    33121 agtcgcttct ccctttaatg tagcatggat ctcatagaaa tcatgatgat gatagatcgt
    33181 tttattttgg ctgacgacat ctttgacatg atagatttca tactgatcag aaaccatcgt
    33241 attgacttgt tcaccgctga ttttcttttg gagcatgtgc cgcacctcct tttgttcact
    33301 tatgcacaat tttattatac cacgtttttt gtaatcaaaa agagctgctt ttatatactc
    33361 ttataaaaaa gaagagacgt ggcatcttct agccccgccc cctccattct aaatattagt
    33421 taaccaacgt cttctttaca ttattcaaga agacttcttc cataacgaat cccatcatct
    33481 tttgtttctt caagaaccac atacaggtac ggacgattct tcatgatgat ttctttgatt
    33541 tttgtgtact cgatcacacc gtctcccaaa tttaccggca cgattttttc ctgttcgaca
    33601 cgaaaatctt tcaaatgaac cgcacatatc ttttcaccaa aacgttcaaa agcttcttct
    33661 accaattgga cttgttcttg ataatcacta cttgtgatca aattggtcgg atctaaaatg
    33721 attcctagat agtccgaatc tactgcttgg atcagctgct ctacccttgc taaagaatac
    33781 accggatgat tcaaacctgg ttctatcccc accatcattt ggtatttttc tccagctttt
    33841 accaagcgac ggataacgga cacagcttca gcaaatgctt catctgtgaa attttcttcc
    33901 gtatattgga tttccggcaa aacacatcca gtttccgaag caaccatcga cgcaccaaag
    33961 gaagaagcat agcgaagata ctgctcgaac tttgtcagca actcttgtcg tatcgttaaa
    34021 tctggatgaa tcatattgat atagcaactt aaaattccta cggtcacttc ttgcttttct
    34081 aaaactcgtt tgacataatt tcccatccca gaattgatct catttgcgcc agaaggtatt
    34141 tcaggaaacg aaagacctaa ggcgagctgc agtgtatgaa tcccttgttc ttttgttttt
    34201 tctgcaagat cttctatcgt ttggacttcg gaaagatcat gtcctctaat tgtaatgttc
    34261 aacataacta ttctcctaac tcagcatatt gggtagccac atgacgattt gcgggaagta
    34321 agtaatcaaa aacaagacga ctaagataac cccataaaaa ggaagaagcg gtttcagcat
    34381 tgcctctgct tttacgcctc ctacacttgc accgacatat agtcctgtac ctactggcgg
    34441 cgtgatggag cctacacaca gattcatgat tgaaaacaac ccgtaatgta caggatcaac
    34501 ccctacactt gtgacgattg gtaaaaatat tggtgtaaaa atcaagatag caggcgccac
    34561 atccataaac atacccacca gtaataacac aagattgact aataacagaa taataaattt
    34621 attatccgtt acgcccataa tcaacgaact aattgcctga ggaataccgg taaacgccat
    34681 ggcgaaagac atcatggaag aagtagccaa taagaacatg atcgtccctg acattgctac
    34741 tgattgaaac aacatattag gtatatcttt tagttttacc gttttatagt aaaacatagc
    34801 aatcaacagg gagtaaatga cagctatcgc tgaagcttct actgctgtaa atatccccgt
    34861 caagatacca ccgataatga tgacaatcaa tagaaggcta ggaatcgcct cttttattat
    34921 ttttccagca tgagccatct gtcctttttc gacaacaggg tatttattct ttttagcaac
    34981 gatgaatgct actagcatga ttcctagcgc ccacaaagcg cctacgagat aacctcccat
    35041 aaacaaagca gagatcgaag caccaccagc aacaagtgaa tacatgataa aagcagtact
    35101 tggaggaatg accatacctg tcggagctga cgcgatattg accgctgtcg caaacttccg
    35161 gtcatatcct tcttccactt gctgagggat caacactccg ccaatcgcgg tagaagcggc
    35221 aatggccgag ctagagatgg aaccaaataa agcattccct aacacattcg tatgagccaa
    35281 agcccccggc acgcgcccga cgaacaacat cgcaaaatcc actagtttct tagctatccc
    35341 tccattattc atgataatgc ccgagagaac gaaaaacgga atagcgatca gcgaaaaact
    35401 attgatactt cccaccattt tttgagctga actaaaagca gaaacatcaa acggtataac
    35461 taacaataaa gtcatcatcg atgagaatgc aatacttata gcaatcggca tccctaatac
    35521 aagcaacaca acaaatacaa aaaataacac taatccggct tctattgcca ttttattcct
    35581 ccatttttat attttttctt gaattgctgg cttgttgctt aatgtatcga ttagattgat
    35641 caggctatag ataatgatga gtacccccga tacaggtact gacagataaa catatcccat
    35701 aggaatactt aaagaaggcg agatctgccc cattgtcaat gtgacagcat tccatccgcc
    35761 atacaccatg atcatcgcag caaataccag aaataaactt tgaacaacaa cttctaaaat
    35821 tttacttttt ttgccagtta atttttcact taaaaccgtt acggctaaat gtgctttttg
    35881 tcccacaaca tacgcggaag acaacatggc aaaccagaca agaccgaatc gaacaagctc
    35941 ttccgtgacc gtatttggat ttcctaaaac cgttctggaa aatacttgcc ataaaacaac
    36001 agcgaccatc ccaacaagca aaacagctcc caggatctct aataccttgt ttaaaatcat
    36061 tttcatcaca gctacgctcc ttgctcttgg atcttttgat aaaggtcttt gtaggtagga
    36121 tcgtttttga atatatcatg aagtggggca actgcctctc gaaacggtgt attatctaca
    36181 tcattgaatt ggactccatg ttcttcttgt gctaaagctt tttcttcttc aattgctttt
    36241 gcaaaagctt caatttcaaa aaccgttgat tctttcgctg cttcttcaat ggctttttcc
    36301 tgctcatcag ttagctgttc tttgatggca tcattcatga tgatgatatc tggcacacgt
    36361 gtatgctcat cataggaata gtatttagcc acaccaccat gtccagctgt atacaagaca
    36421 aattcattgt tttctgatcc gttgatcaaa ttggattgaa gagacgtgta cacttcatca
    36481 cttcccatag gtacgggcga accgcctaaa agctctacca ttttgatagc ggtttcgctt
    36541 tgcatcacac ggatcttctt tcccttcaaa tcttccggcg tatggatcgg accgtctacc
    36601 atataaaagc tgcgctgacc agaatcataa taggtcaatc cggtaaatcc taaatttttg
    36661 gtcgattggt agattggctc cattatttct tcattatcca tcaccttaaa gaaatgttct
    36721 tcatcattga atagataagg aactgaaaaa atcgaataat ctttagagaa actttccaac
    36781 gctgaggcac ttacttttgt gaaatctact gctcctgact gtgtcaattc gatcagttca
    36841 cgttctccac ccagttgtcc atctgggaaa tactggatct gtacggaacc atctgttttt
    36901 tcttttacta aacgcccaaa ttcattcatt gcatcaatta ctggctggct gttgcttgca
    36961 taagcaaagc gcaaggtaac tatctcattt acatctgcat ctgcgacagt tgccacacta
    37021 gaattatttc cgcagccgct tagacctagc agacctaggc taagcgaact tgctgcaaac
    37081 agcagtgatg tttttttcat atgggtttcc tttcttttaa caataagaga cgagcaattc
    37141 tgtcaaacaa agcaccgtta acgactgtcc ataaggcatt gctgtgattc cgatattccg
    37201 ataaaaatct aaactgtccc ccattcctgt cccgattgaa acgttttgaa cttctccttt
    37261 ttcatcgatt tgttcaagca atccttggat agcacgataa gcgacttctt tatattcttg
    37321 tggtaaataa cgtttatgga ccgctttcaa aataccgtaa gcaaatcctg cagttgcaga
    37381 agattctacg taagaagaag gatcatccaa caacgtatgc cataaaccgc tttcagactg
    37441 ataagttttt aatgcacgca cttgtgcttc aagtgtttcg atcaataatt tgcgcaatgc
    37501 atcttctttc gataattcta agatttcaat gatctctgga atagcaatcg tcaaccagca
    37561 gtttccacga gcccaaaatg cttcggcata gttatgattt ccttcaaacg tccagccgtg
    37621 ataccacaat cctgttcgtt tatccatcaa gtatttgata tggatcataa actggtaacg
    37681 agcttcttct aaatattctg ggcgattcaa cagtttcccg atttttgcca aaggaagcac
    37741 tgtcatcatc aatgtatcgt cccacaactg attcttattt tccggtccat atgtggcatg
    37801 ctgtaacccg tcttcatttg tccgaggcat gtcattcatg acccattctg cccattgttc
    37861 taaataaggc aaatagcgtg aatctttcgt gtcttcatac aagtaagcca tagtcaatag
    37921 cggtgccatt gtattgacgt ttttgggcgg agcgccttct tccatacgat cctcaaacca
    37981 ttcattgacc acttgataag cgcgaggatt ttttgtcatc tggtaatttt tataaatacc
    38041 atatagaccg acaccttgtg gccaattcca cactgtccag cttttgtcat ctactttcag
    38101 tccatcaaag tccaacaaaa attcaccatt atcgtctttg atcgttgtca ggttttcaac
    38161 gagcaggtca attttttctt tcactaattc tttaggtaca aaaatctctt ctttaataat
    38221 catctttacg ccaccttttt aaacgctttc attttatatc cttaatatag cagtaatacc
    38281 gtccactata aatatcgctt tttgaacaaa aactgtctaa aattgaccta aatgttaaat
    38341 aacaaaagta actttcagtt acttggaaat taaaaaaaga acttggagaa acaacgtttt
    38401 ccaagttctt tttcatctat tttcttatct tttttctacg ctttcttttg cttatccgtt
    38461 gtaagcatca atgatgatct gtttcaattc agagatcaat ggttctttcg gattagctgt
    38521 cgtacattgg tcttcgtaag ctaattcagc catacggtct acggttgtat ctagtgtttc
    38581 ttgtgtgact ccttgagctt ttagactcat gttgatgccg acagattttc ctaattcata
    38641 aacagccgtt gctaaagctt cgactaattc ctctgttgtt tcgcctttca gacctaagaa
    38701 ttttgcgata tctgcgtaat ctgtatctgc acggaaatag tcatatttag ggaacatcgc
    38761 atgtttttgt ggatcttttg cattatagcg gataatatgc ggtaaaagaa tcgcatttgt
    38821 ccgtccatga gggatcccgt attccccgcc gattttatgt gcgactgagt gacaaatacc
    38881 taggaatgcg ttagcaaacg ccataccagc cattgtagaa gcgttgtgca ttttttcacg
    38941 tgattccata tcaggtgttt ttactgattt ttctaaatag tcaaagacta acttgattgc
    39001 ttgtaggctc aatccacgtg tataatctga agccatgact gaaacatagg attcgattgc
    39061 atgtgttaac acatccatcc cggtatctgc tgtgacagat gctggaactg acatgacgaa
    39121 ttgaggatcg acgattgcga catctggcgt caatgcataa tctgctaacg gatatttcac
    39181 atgtgtttca ctgtcagtga tgaccgcaaa tggcgttact tcagaaccag tccctgatgt
    39241 tgtcgggata catacgaatt gtgttttttc tggtttgtcg atcttatatg tccgtttacg
    39301 gatatccaag aatttttgtt ttgcaccaaa gaaagatgtg tctgggtgtt catagaacat
    39361 ccacattccc ttagctgcgt ccattgcaga accgcctcca agagcgatta ctgtatctgg
    39421 cttgaagtct gccatcagtt tcgttcctgc gtatacggta tttgtcgatg ggttcggttc
    39481 aacatctgag aagacttcga tcttcacatc atttttacgt cgtgccaata cttcacgaac
    39541 tgtatcgcag taaccgaatt ggaccatacc agggtcacaa acgatcatga cacgttcaac
    39601 gttttccatt ttctctaagt acaatagaga gttcttttca aagaagattt ttggcggtaa
    39661 tttgaaccat tgcatgttat ttctccgttt cgctacagtt ttgacattga ttaagtttac
    39721 agcagagacg ttacgagaaa cagagttctt accataagaa ccgcatccca aagtcaatga
    39781 cggaatcatt tcgttataga tatcaccgat gccgccttct gcagatggtg tattcactaa
    39841 aatacgacaa gctttcattc gaagaccgaa tttgacatgc aactcttcgt tttctgaatg
    39901 gataactgct gtatgtccta atcctccaag attcaacata ccttcacaca aatcaaacgc
    39961 atggtccgtg ttgttagctt tgatcatggc aagaactgga gaaagttttt ctcttgatag
    40021 cggataatct gggcctacgc cttccaattc agcaatcagc attttcgttc cttttggtac
    40081 actgattcct gccaattttg cgatttccat cgcagaatgt ccaacgattg atggattgac
    40141 cgcatatttt ccttcgttca tcactgcatc ttctaatttt tgcaattcat ctggttttac
    40201 gatataaact tggtgtgctt ggaattctgc ttttactgct gcatagattt ctttatccac
    40261 gatcacagct tgttcagaag cacaaatcat tccattatca aatgttttcg aaacgatcaa
    40321 atcgttcact gcacgtttaa tttttgctgt tttttcaata taagctggta cgttacctgg
    40381 acctacacct aaagctggtt ttcctgtaga gtaagcagac ttgaccattc cagctccacc
    40441 tgtcgctaag acgatcgcga tacctggatg gttcattagc atagaagtcg cttcgatcga
    40501 aggatgttcg atccattgga tacaattttc aggagctccg gcagcgatag cagcatcacg
    40561 taccactcgt gctgcttctg cagaagattt ttgggcactt ggatggaaag caaaaacgat
    40621 tggatttctt gttttcaacg cgatcattga tttgaaaatc gttgtggaag tcggattcgt
    40681 tgttggagtt actccgcaaa ccacaccgac tggttcagca atttcaatca accctttttg
    40741 gacatcttca ttgatcacac caactgtttt atcatgtttg atattatgcc aaatatattc
    40801 ggacgcatac atatttttga ttgctttatc ttcgtaaaca ccgcggcctg tttcctctac
    40861 agccatcttc gctaatggca tatgttgatc caaagctgcc attgccattt catgcacgat
    40921 atggtctact ttttcttgat caaagctttc catttctttc aatgctgcat ttgctttttc
    40981 tgccaaatca tcaatcattg cttgtacgtc aattgtcttc gttttttctt tttctattac
    41041 tttagccatc attatcctcc taatgggtca tggttatttg ttaaataatt cacatgtata
    41101 tcatacaata tttatttttc tatgtaaaca cttttttgtg atttttttca cagttatttt
    41161 taaatataaa attgctttat ttacaggtgt ttgtatagaa aaatatataa agttatttat
    41221 tattatttat atgacacacc cgattattca atattgagca atatatccca tgctcttatc
    41281 tctttctttt ttgaataaaa aatgaggtag gacatctttc tgccctacct cgtctttaaa
    41341 taagctttga tacttatttt tcttccttct cttctgtctc ttccagcgtt tctgttgttt
    41401 cagtttttac ttcaactgtc tcagctggtt cttctgttgt ttcaacagta gtcgttgcat
    41461 catttgttac gacagtccct ggtttgaccg ttttgattgc tgcacgatcg tactcaagga
    41521 agatcccttc gcagtctaaa acaactgtcc gtttgtcatt gtcgatttct gaaacaactc
    41581 catgtaatcc gccgatcgtt acgactgaat cacctggttt catgctatct aacaagtttt
    41641 gacgttcttg ctgttgtttc ttttgcgaac gtgacataaa aaaccacatt gctaatagcg
    41701 cgataaacat cacaagcatt ggtaatgttc ccattttttt cacctcacta attctgtatc
    41761 tacaaaaaac actttagcag aaaaatgctg ataacactag ttttttactt aatttttaaa
    41821 agattttcct ttagaagctt tttgcgtttt ctttattgaa cccgtattct tcaaaaaagg
    41881 cttctctaaa ttcaagcaaa ttatcatcca tgattgcttg acgtacttgt ttcattagat
    41941 tcaacaagaa gtataaattg tggtaagaag tcaaacgaat cccaaatgtt tcatcacatt
    42001 tgatcaaatg gcggatatag gcacgtgtat agtttttaca tgtataacaa tcacatttct
    42061 catcaattgg acggaaatca tgggcatatt tcgcattttt cactactaga cggccttgag
    42121 aagtcataca tgtgccattt cgagcgattc gagtaggcaa gacacagtca aacatgtcta
    42181 ctccacggat aacaccatcg atcaatgaat cagcagcacc gacacccatc aagtaacgtg
    42241 gtttgttttc ggggatcaac ggtgtagtga attctaatac acgattcatt tctgatttag
    42301 gttccccgac agataacccg ccgattgagt aaccagggaa atccatcccg actagatctt
    42361 tcgcgctttg acgacgaaga tcttcaaacc ctgctccttg gatgattcca aataatcctt
    42421 gacggtctgg attagcatga gctttcaatc ctcgttctgc ccatcgagac gtacgttcta
    42481 ctgatttttt cacgtagtcg taactttcat cgaatggtgg acattcgtca aaactcatca
    42541 tgatatcaga gcccaattta ttttggatgt tgattgcttt ttctggtgat aaaaacatac
    42601 gcgaaccgtt caagtgattt ttgaaatgca cgccttcttc ttcgatattc cgcatatcac
    42661 ttaatgaaaa aacttgaaag ccgcctgaat ctgttaaaat cggttgatcc cagttcataa
    42721 atttatgcag tccgccagct tcttctacta agtcttcacc agggcgtagc cataaatgat
    42781 atgtattact taaaataacg ccagcaccca tttctttcaa ctcttctggg gacattgttt
    42841 ttactgtagc taatgttcct actggcatga acattggtgt ggggaaagtt ccgtgtggcg
    42901 tgatcaattc ccctaaacgc gcgccagtat gtttttcttt cttgattaaa cgatagcgaa
    42961 tggcaggttg cgtcattcat ttccctactt tctatataaa atatcttgac aactcccacc
    43021 atcataatcg tttcaagtgc tttttgcaag ttccctcggc ttccttctac tttatttaat
    43081 attctttttt ttatcctttt tttatgaata acaaaaaaaa gaaaaacatt atgacagaaa
    43141 tattttttga tacatggtat attggtgtta ttaaagaaaa ggagggaaaa atcatgcaat
    43201 cttctgcaga attaaaacgc caagcaaaag agagtctaaa aggacgttgg ggacaagctg
    43261 ttttactaaa tctaatccct acattgattg gtattgctac tattcttctt attatgattc
    43321 ctattatctt gtttgccacc accatatatg atggatcagc gagcgtctca gaagcgacaa
    43381 cttcaggagg cggtagttca ggaggcggtg gcggaattat ttccagcatc attagcgctt
    43441 tgttcatgag cggtatttct tggacttatc ttgatatttt acgtggataa aaagatcaga
    43501 tcgaaccatt caaagatgca tttcgtggat tcaaaggttt gtttatcggc ggagtgatca
    43561 gcttagctgt gctgatctcg atctttacaa cattatgggg tttgctatta gttattcctg
    43621 gaatcattaa aagctattct tattctcaaa gctattttat ttactacgat atcgtccaag
    43681 aaacaggaca aacacctaaa gtactggata cgatcactgc aagtcgaaaa ttgatggatg
    43741 gttataaagg acaacttttc tggttagatc tttcatttat cggctggcat atcttagcat
    43801 tagcaactgc tggtattggt tatctatggc tcagcccata catttctgca acaaaagcag
    43861 cattttatga acaattgcca aaagatattt aaaagagagt gtgacttgtg accgaggggg
    43921 tggcaggaga acaccgttta tcgagaggca gtaaaagaaa cattcagccc attagcaaaa
    43981 aggaggtgtg acaacattca tgtcacacct cctttttgta tagttccagt aaaaagaaaa
    44041 tcaacttaga aacagttaat cattcctctt cttctgcttc cggtaatcga tggaacttga
    44101 tcagttcatt caccgcgatt ggtacgatag ataaaatccc taccaagaac cagtgattca
    44161 aactgatgtg tactaggccg aatagttctt gcgtaaatgg cagcaaagca acagccgttg
    44221 taatagctaa tgccagtaac gccatttcta ccaaagcttt attggtcgct aaattgactt
    44281 tgaagatcga ttggctgctg cgtacattga acacatgcag aatcgatgaa taagctaaga
    44341 tcaagaatgc aacagtttga ccgacatgct gacttgcgtc tacccatggg ctgatagtat
    44401 cgacataact acctaaataa taaccaaaca aggttacgat ggtgaagacc cctgcattta
    44461 tggcaatttt ttgcaataaa cctcgagcaa agatcccttc atttttcgga atgggtggct
    44521 gatccatgat gccgtgttcc gctggctctc ttcctaaagc aaatcctgga agtccatcag
    44581 caactacatt gacaaacagt agttgcacag ctgtaaatgg tgctccccat cctaacagca
    44641 tcgcaatcaa aacaataaag atctccgaaa tattacagct tagcaaaaag ttgatagctt
    44701 tacgaatatt ctgataaacc gaacgtcctt gactgacagc gtctacgatc gtcgcaaagt
    44761 tgtcatccgt caaaatcata tctgcggcac tttgcgccac atctgttcct gtgatcccca
    44821 tggcacaccc aacgttactt gctttcaacg ctggtgcatc attcacacca tccccagtca
    44881 tcgctacgac tgcacccgta cgttgccaag atttgacgat ccggatcttg tcttctggcg
    44941 ttacccgagc atagacagag agagctttga cacgcgcatc taattcttcg tctgataatt
    45001 gatgcagttc tgatcctgaa agtgcttctg acggatcatt caagatacct aattctttcg
    45061 ctatggcact ggcagtcacc acatgatctc cagtgatcat gactgttttg atgccagcct
    45121 ttttcgctcg cttgattgct cctttacttt ctggacgtgg tggatcgatc attccgatca
    45181 gaccaatcaa acgtaagtct ttttccagtg cttcagaaga aatatcttgc ggttcttcgt
    45241 cataagtagc ataaccaaca gcaatcactc tcagtgcccg tttaccaaag cgatcattaa
    45301 cgatcgccgc ttgttctaca tcgcctgaac taaagcgcgg agcaagaaca tcgaatgctc
    45361 ctttggtgat tgagatgtat ttttcgccca tttggtgaac tgttgtcatc atttttcgtt
    45421 cagaatcaaa aggaagctcg tttactcgtg gatatttttc ttctaattct gcctttgtat
    45481 gataattctc ttcaacagcc cttacgatgg ctacttctgt tggattacct ttgataacaa
    45541 ggtcgtcatc ttcttgctcg accgtcacat ctgtacatag tgcagccatt ttcaatattt
    45601 ccatcgcgct gttcgtcatt gaatcttcga tattcgttac ttcatcttct ttgctccata
    45661 cccggcggac gcgcatttca ttttgtgtca gcgttcctgt tttgtctgag cagataacat
    45721 tagcggttcc tagcgtttca actgctggca actgtcggat gatcgcatgt ttcctcgcca
    45781 tcttctgcac accgtatgca agtgtcaacg taacaataac agtcaaggtt tccggtacag
    45841 ctgcaacagc caaggaaatc gaagtcatga acatctcaag gagtggttct ccttgcagtt
    45901 caccaatcac aaatactaaa gccgcagccg ctaaagcgat catactgatt cgtttgccta
    45961 gctgattcaa tcggacctgt aaaggtgttt tttgcatagt attttcgttc aaaagatccg
    46021 cgatcttacc catttctgta gccatgccaa tggcagtgac gatcgctttc ccacgacctg
    46081 cagcaaccgt acatccttta aataccatat taagttggtc acctaatgac tcatcttctt
    46141 cagcaataaa tgctgcatct ttttcaactg cttcactttc tccagtcaac gccgattctt
    46201 ctacacgtaa ttgtgatgct tcgatcaaac gggcatcggc agaaatagca tcaccggact
    46261 ctaaaacaag aatatcaccc actaccagtt gctctgactc aacagtggtc actttgccgt
    46321 ctcgtatgac agttgccgtt tgtttattca tatcttgcaa ggattccagt gctttttctg
    46381 cgtttccttc ttggacaatc gccaataccg agttgatcac aacgatagcg atgatcagca
    46441 gtccttcaaa taaatcccca tgttctgtag caaatgcggt ataaaaggaa atcaccgctg
    46501 ctacaagaag gatgatcgtt gtaaaatcgg acaagcttcg aaagaatttt ttgatcatcg
    46561 attctttcgg cgcctcatcg aatttattca atccctgctt ttttcgccgt tcatccactt
    46621 cttgtgaaga caacccagta tctggatctg cttctgttac cttctttact tcttctattg
    46681 tctgcttgta ttcttccatc ctattcctcc tttaaaatct tcgtacaaaa aaaggtactt
    46741 attttactat aacatccttt ttttatttac ttcaaataaa gggcttatcg attatttgtt
    46801 aagaaagcgt aaaatttaaa gtgcttatat ttgcaaacgc taccaaagga tgctattata
    46861 tagatgtaag gaaggaggat accatcaaat agacagaaga atttctcgat agaacagtgt
    46921 aagcaaacaa agttgttaga agtacaggtt tcacccagac atgcgtgtag agtacaaacc
    46981 tataaatagt gaatgcgtat ggatgtttgg atcacgaagt atccgaaaca agaagtaatg
    47041 cgatacgtaa caattgaata acgtaaacgt ctgaaaattg aataggaaca agagatgttt
    47101 caaatgttga agatgtaacg aaaacaaaat ttttgtttaa catgaagaaa ttcaacaccg
    47161 tgctttgcat gtatgatgga aagttacaat catttctgtt tatttgaatc cttccgaggt
    47221 acaagaaagc cgagcttatc gagagctcgg ctttttcttt gtcataaaat ctttgtaaag
    47281 cttttttgtt attcaaaact agcggttttt cataacctta tttcacgaac atcgcatctc
    47341 caaaactaaa gaaacgatag cgctcttcaa tcgcatgctg gtaagcagat aaagtcaatt
    47401 ctcttcctgc aaaagcacta actaacatga ctaaagtcga ttttggcaaa tggaaattag
    47461 ttgagaaagc ttctaccact ttgaattcat agccaggcgt aatgaaaata tcagtccatc
    47521 cgctgtctgc tttgatttct ccattaaatt tcgttccaat cgtttctaat gttcgaattg
    47581 aagttgttcc gacagccacg attttcccgc catttttacg tacttggttc aatcgctcag
    47641 ctgcttcttc cgtcaaacgg tagaattcac tatgcatatg gtgttcttca attttatcta
    47701 cgctgacagg tcggaatgta cctaacccta catgtagtgt cagatagact aattcaacac
    47761 cctttgcttc gatctcatca agtaattctt tcgtaaaatg caatccagct gttggcgctg
    47821 cagcagaacc attttctttc gcatagacag tttgatagcg atctgggtct tccagacgtt
    47881 ctttgatata tggaggcaat ggcatttctc ccaatgattc aagaatctct agaaaaattc
    47941 cttcatactc aaagtcaatg atccgtccgc cgtgttccaa ttcttctttc actactgctt
    48001 gcaatctgcc atcaccaaaa gagattcttg tcccaacttt ggcacgtttc gcaggtttga
    48061 tcaatgtctc ccacgtatct ccttgtgtat tcgttagaag aaggacttct aaatgcgcac
    48121 cagtatctgg tttttctcca tataaacgag caggcagaac tcgtgtatta ttcataacta
    48181 gcgcatcacc aggctgtaac tcttcaatga tttcatggaa atgtttatct tccatctctc
    48241 cagttttccg atccaaaaca agtaaacgag aatgatcgcg gtcttttaat ggtgtttgtg
    48301 cgattaattc ttccggcaag tcaaaatcaa aatcttctgt tgttaacata tcgtcactca
    48361 ctttctatca tgtgcttcat cattctatca tgtttttcgt tctgttggca aaatcagcac
    48421 tttttcactt ctattttttg ttttcctaaa taaaaaaact accctatttg tattttttca
    48481 ttgttttagg catactagta atagatagtt cttcattgaa aatagaaaaa gaggtggcac
    48541 catgattgaa tttcaaaatg tgtcaaaaat ttataaaggt ggaaaagtcg ctgtagagga
    48601 cgtcaatctt tcatttgaaa agggtgagtt catttgtttt atcggtacga gcggaagcgg
    48661 aaaaacgacg acgatgcgga tgatcaaccg aatgactgat ccaacacaag ggaaaatttt
    48721 gattgatgga aaatccatcc aagaaattga tccagtggaa ttgcgacgtc agatcggcta
    48781 tgttatccaa agtattggat tgatgcctca catgacgatc cgtgaaaata tcactcttgt
    48841 ccaaaaattg ttgaaagtca gtcaagaaga acggaataaa acagctgaaa aaatgattga
    48901 tcttgtggaa ttgccccgtg agatgttaga tcgctaccca catgaattat ctggtgggca
    48961 gcagcagcgt attggagtcg ttcgtgccct tgcagcgaat caagatatca tcttgatgga
    49021 cgagccattc ggtgcgcttg atcccatcac tcgtgattcc ttgcaagacc ttgtcaaaga
    49081 tttacaagag cgtttgggaa aaacgatcgt atttgtaacc catgacatgg atgaagcgat
    49141 taaactagca agccgtatcg ccatcatgag tgaaggccgt gtgatccaat ttgatacacc
    49201 agaaaatatt ttacgtcatc ctgcaaacga tttcgtagaa gagttgattg gagaagatcg
    49261 cctactacaa gccaagccaa atgcgacaag agtcggagaa gttatgctaa atacagcaat
    49321 cacgattaca ccggaaaaat cattacaaga agcaatcaaa cttatgaggg aaaaacgtgt
    49381 agatacgttg ttagttaccg ataattcgaa tgtattaaaa ggatttatcg atgtagaaac
    49441 gttgaataaa aagcgaggaa aagtatccag tgtcggcgac atattaaata aacatgtttt
    49501 ttacgtaaaa gaatccgcct atcttcgtga taccttgcaa cgcattttaa aacgcggact
    49561 gaaatacgtg ccggtcgttg atgaacagaa caaagttgta ggtatcctga ctcgtgcatc
    49621 attagtggat atcgtctacg atgtgatttg gggagaagat cccgcaacta ctgatgttgc
    49681 agagtcagct actcctgaag aatctaagga ggtctgacct atgcagcagt tttttcatca
    49741 acacggttca gaaattctct caaaaggttt tgaacatctt tatatttcgg gacttgcttt
    49801 gatcattggt atcatcattg ctgtaccgct tggtgtctta ctgacacgtt ttccaaaagc
    49861 tgccacgatt gtgattggct taaccagtgc cttgcagaca atcccttctc ttgctttatt
    49921 ggcattgatg atcccgctat ttggcgtagg taaattacct gcgattatcg cactctttat
    49981 ttattcatta ttgccgattt tacgtaatac gtacattggg atgaaaaatg tcgattggaa
    50041 ttatcgggat gtggcaaaag gcatgggaat gactgagttc caatccattt tttccgttga
    50101 attgcccatt gctatgccaa cgatcatggc tggtattcgt ttagctgccg tttacgtgat
    50161 tgcatgggct acacttgctt cttatatcgg ggctggtggt ttaggtgatt tgatttttag
    50221 tggactgaat aattaccaac cagatctcat tttggcaggt acgatccctg taacgatttt
    50281 agcactattg gctgattggc ttctaggtct cttggaacac cggctgacac cgatcgcact
    50341 tagagaggag aatgaagaat gaaacgtata ctaaaaatga ccatggttct tttctctctt
    50401 cttatacttg cgagttgttc tttccctggt cttgccagca atacagatga agacaccatt
    50461 tcgatcacag gtggaatcac ttcagaagca cagatcttag caagcctagt tgccggaatg
    50521 gttgaacatt atacagataa aaataccgca atcatcaaca atctggctac cacaactatc
    50581 aaccatcaag cgatgatgaa cggagatgct tcaatttcag cggctcgcta cacaggaaca
    50641 gatttaacga ctacattgaa ccttcctcct gaaaaagatc cgaaaaaagc gtttgctacc
    50701 gtgaaagatg aatttgagaa aagatacgat caaacgtggt tcccgtccta tggttttgaa
    50761 aatacgtatg tctttcttgt tcgaaaagac accgcacaaa aataccattt atctaaagtc
    50821 agcgatctga aaaatgtagc ggatgaatta gtagctggtg tagatacttc ttggatcaat
    50881 cgtaaaggag acggttatga cggcttccaa gaaacttatg gcttctcctt caattcgata
    50941 ttacctatgc agattggact tgtttatgac gcagtcgaag caggaaaaat ggatattgtt
    51001 cttggctact ctacggatgg acggatcgcc agttatgatc tagtcatgtt ggaagatgat
    51061 cgtcaattct tcccaccata tgatgctgct ccagttgtag acaacaagat attagctgat
    51121 acgcctcatt taaaagaagc cttaaataag ttaggtcata ccatcagtac ggaaaaaatg
    51181 caggaattga actacgaagc agataataat ctagtggaac catcagtagt agcacaacgt
    51241 ttcttacaag aaaaccacta ttttgaaggg aagtgaagca attggataaa atgaatgtct
    51301 ttcaacaatt tttctattat ttccaggaaa atggctccta tatctttgca caatttatcc
    51361 gtcacttcct gatttctatc tatggtgtcc tctttgcagc agttgtcggg attccggttg
    51421 ggatcatgat ttctaggaga cgtaaattag caaactgggt gattcgtttg gcgaatatca
    51481 tccagacgat cccttctcta gccatgatct ccattttaat cattggatta ggcctgggag
    51541 tcaatgtcgt gattgttact gtatttttgt attccctctt accgatcatc aagaatacgt
    51601 ataccgggat gatccaagta gataaaaaca tccttgatgt cggcaaaggc atggggatga
    51661 ctgctagaca acgactattc atggtagagt taccactctc tgtttctgtt atcatggcag
    51721 gcataagaaa cgcgttagtt gttgccatcg ggataaccgc gatcggtgca ttcgtcggtg
    51781 ctggtggtct tggagatatc attatccgag gaaccaatgc aacagatggc acatcgatta
    51841 ttttagcagg tgcattgcca actgcattaa tggcgattat cacggactgg cttttaggta
    51901 ttttggaaag acggctagat ccagccagcc gtacatcacg ctgatgttat tgtaaaaaac
    51961 aaaagcttct gcgaccattt gttggtcgca aaggcttttt tagttctgtc attttttaag
    52021 gcaataatcc actctgattc ttccctcctt atgggcaaag agttgctttt cttagctatt
    52081 tatccattct gtatactcca acttcatact gccaacgggt tcatctctgc atccaccgac
    52141 taagtttttt tcttatccgc taaggcattt tgccaatcca ttttcccatc actcgtcatg
    52201 gaattcatac cacatgatct ctaaatactc gtctgcttgt tctttgaatt gggcatcaat
    52261 tcttacatcc tttggcgtgg ctttcattta agccttttcc atcagtcctc gattgttcga
    52321 tgccttcagc tgcatcatca aaactggtga ctgccgtatc ggtaacttcg atcatctttt
    52381 atacaatcgg gaacttgcca tcctcatcct tggctaaaaa catatctagc cattccagct
    52441 tctcgccatg ggaggtttgc ggttcctaaa accggtacac gattcttatg gactgcatcc
    52501 gtcgcaacta gacttggcga tacgatgatc cttcaccaga agagcacccc cgtaaaccaa
    52561 ttgatcgata tattgccaat aagaaaagac attggcgtaa aagatatcga tccctcgtga
    52621 tgcattgccg ttgatactgc tattcatggc cgaaagcgcc acgactttga cttcttccgt
    52681 ttgagtgaca ttcatgttcg gcaatgtcgc tttggatacc cgctctgcta aaggaacgac
    52741 actggtattg tatttcgtat ctgtatcttt tccaaaagac catgccaacg aatcctctgg
    52801 gaaccaataa gacgactccg gttgattgtc cattgctttt ttcaacatac ttttggctgt
    52861 ttctcgataa acgacatttc caattgtctt cgcctcactt tggcgataat cgatggtcgt
    52921 tgccactgcc aacactaaca acgatgctcc aattttactg attttccttg tcacacttct
    52981 tcctccttgt tttacataaa cccgtcaaca ttccattcct aaactcaaac aatgaccctt
    53041 caaaggtgga gatataggaa caaattaaag aaatcatgca ataaatccaa gaaggttggt
    53101 tttagaacaa aaaaagagtc tcctttttgg ggagactctt tgttaactat ctaaaaaggt
    53161 tggctcttct cacttcactc ataatgtgtc caggcagaat aaatttccac aactttattt
    53221 tcctcatcaa ctttgtaaac cactcgatgc tgtctattca gcctgcgtga gtatctgcct
    53281 tcatgtgtag gtctcagctt ttcaaaagac tgcgtgggca tatatggatc ttccttcaat
    53341 gtctgaatca cttcttcaaa ttgtttcttt aaattcgatt gcttgatttt tcttaaatcc
    53401 actttcgcag agtttttgat tgcgactgta tagttactca tcaaagagct tcccaatcaa
    53461 tatcatcgat attcgtaaag ccactgtcat ctttttcgcg gtctcgtact ttatctaaag
    53521 tacctgtttg ctcaagaaaa agggtttctt gaatcgctct ccagtcttcc agcccaatca
    53581 atacagcatt gtttccacta cgatcactaa taatctcgat ttcagtatga ttttcattta
    53641 cctctttcaa taactgataa aaatttttac gagcagtgct aggattcatc gttgtattag
    53701 ccattgtctc tcctcctttt tctgatataa ttatagcgta cttgattaag tacgtcaaaa
    53761 aatacaataa agcacttaaa ttcagcaaac ttttcctctt ttttacatag agaaaaagac
    53821 ccctttttag ggaggatctt tgtccacgct cacttcttac tcctttacga ctagcggtag
    53881 ccaaacgtaa agtaattggt aacaacgtat catctttagc aaaggtcgaa tccaaagcct
    53941 gtgagtctat gcaacaacac caatacacga aggttcctcg ttgcagtgtg acttgattga
    54001 tatcttgaat aacctgagga tacgcacgaa agatttgtaa cggttattca aaactgattt
    54061 tggccgtcaa gtcttctact gcctcaaaaa tgattgcctc tttcgtctcc tgtcattcat
    54121 gttcactatc gatttgatac ttgcttagac cgttgggttt gtgaatcacc aattaaaaat
    54181 ggcactgagt tatggtaaca aaaaatggtc acttgacgag gctgagattc ctacttatgg
    54241 cgccagatta ttaaaaggca gtatttagta aaaagggcag cagtatacgt ttataagcag
    54301 cacaatgcaa tctgctcatt gtgctgcttg ttttttattc ttcgcacact tttcgaccaa
    54361 gaaacgcaac gccctgatca ttgattccag agaaaaacaa cctttctttt tggtcgatgt
    54421 actcataata tgggacaaat tcatttcctt cccacaagta acttcgtcct tcttttttta
    54481 attctgttat ttcatgctgt tgagaagata taatttgaga ttcgtaatca aattggatga
    54541 tttcccactt tcctaacaga gtttcttgct ctggcattcg tgaaacactt ccctgataga
    54601 ttgaagcaga gattactggc cagcctgatt ccagccaata gagtttacgt atttgtaaat
    54661 ggaattggtc actaaatggt tttctccgtg catgatgcac aacaaagctt tccttattgg
    54721 attgcgtaaa gatcgaatta tgaccaggag cgtatacaac tgtttcttct gagaactgat
    54781 aactgcccaa cagtttggtc cctacttcgg ttggcgtctt ttcttgatcc gtcatggccg
    54841 taccatgcca gtccagatat ggccctgtaa tttcttttgc tcgggcgaca cggatattat
    54901 acgaatcgtt aagggaatcg aaagaaacaa acaaataata ataatcggtt tcaggatgat
    54961 aataaataaa tgggccttca atagcagtat caactgtttt cggacgaaaa gcaatccgtt
    55021 ggccatagct cttttcttga agttttccag tttctttgtt caatggagca atatagattc
    55081 cgccaaagaa agaaccatag acaaaccact gctcacccga gcggtcaaaa gcaatattgg
    55141 catcgatcgc gttatgctgt gcaagagttg cattggtttt aacaacctct ccttgatctt
    55201 cccaagggcc caaaggatct gatgctgtag ctaagccgat aaaagaagtg gtactgccga
    55261 atgtcgaagc agaataatac atacggaatt cgtccttgta gcgaataact tccggtgccc
    55321 atagtccttg agctttgctc cattttactg ctggttcagg catttctgac aatgcctgtt
    55381 tctcaaattg ccaatggatc aaatcttttg agctacgaat tggtacacca gccgttttgg
    55441 gctgttgtgt gtccgttgaa tataaataaa aggtgccttc atgttcaata atcgtaggat
    55501 catgaacccc attgatcgct gtcatgtctt tccctcatct cctaattgat ttatactatt
    55561 ttataaaaac aggacagcta cttgacgagc tgtcctgttt gttcccacat tcctgcagga
    55621 cagtttttct tagctaagtt tgcgcgaaac cgataaaaac agccacattt ggtacaggta
    55681 tgattcaatc gcagtggaca ggtctcacaa acagcgattc tcctactgac gatctccggc
    55741 aaagccaagt ctctttctaa agaaagttgt tctgcaatca aggattcaat gtcttcctgt
    55801 gctgctacag caacatcttt cacttcgcat cctttacaag tcatgggatc agactgtcaa
    55861 tgagatcgtt agaacactca ttgctggcac acgcaagctg actttgttct cttcaacatc
    55921 gtaagcggtg aagtcttgga tcgccacatc ttcaggatga tcaaaatcat tgtgtgcgtt
    55981 cattttgtct cccacgatat aacgagcttc tttcacttta ttgatcgctg tttcaaggga
    56041 gaaggataat tcttccgtgc cttgggtagc aaaattacaa accgatagat ggatcgtatc
    56101 ctcttttttc gaaatcgtat acgtaatggt atcgctgctg gttccatggc tatcaatggt
    56161 ttcagcatct tgatggactt tgtacaaatc aaatacatga tagcttgggg ttttcaccat
    56221 ttgttcgcca tctgtcaaaa tcatcgcttg caggacgttg acggtttgtg cgatatttgc
    56281 catgtgcact cgcttggcat gtttatggaa aatattcaag gtgatcgctg cgaccatggc
    56341 atcacggatc gtattttgtt ggtataagaa gcctggattc gtaccaggtt ctgctgagaa
    56401 ccaagtgccc cattcatcaa caatgattcc gacacgcttt tctgggtcat actggtccat
    56461 gatagcgctg tggcgggtca ataattcatc catgtaggct gctttttcac aggtcacttg
    56521 ccactctgcc tcattaaatt ccaaggcgct acctttttct tcccagcctt gcggatgaac
    56581 gtagtagtgc aagcttaggc cgtccatcaa ccaatgggcg tttttcatca gcgtttctgt
    56641 ccaatgatag tctgcgacat tcgctccgcc agcgactttg tagatttttt tgtcaccgta
    56701 ttggcggaca taggtttgat agcggcgata cagatccgca tagtactctg gccgcatatt
    56761 gccgccacaa ccccagtttt cgtttcctac gccaaaaaat ttcatttccc acgcttcttc
    56821 atggccattt tctctgcgaa gatcagccat cggagaaatg ccatccatcg tgatgtattc
    56881 cacccattct gacatttctt gcaccgttcc gctgccgaca ttgccgttga catacgcgtc
    56941 acattgcagc tgcttgatca attcaaaaaa ttcatgggtc ccgaaatgat tgttttcagt
    57001 cacgccgccc cagtgagtgt tgaccatcgt tttgcggttt tctttaggac caatcccgtc
    57061 tttccaatga tattcatcgg cgaagcagcc gcctggccaa cgcagcacag ggatttgaat
    57121 gtttttcagt gcttcaacca catcgatccg catcccattt ttatttggga tcggcgaatc
    57181 ttctccaacg tataatcctt catagataca acggcctaga tgctctgcaa aatgaccgta
    57241 gatatatttg ctgatcgttg ttcctgattt tgtgtgtaga attttgattg tcattttcct
    57301 actcctattc tttgattccc caaatggact cattattatc gccaatcgtt gaaaacgtta
    57361 acttttgctg ctcgaattct gttatttcct gagttaataa gattcctttg aaggtagttt
    57421 cttcaaaagt caacaccaag tatcccgcat cgtacgtcca agttccggtc aagtctccag
    57481 taacgtttcc atctttttga aactcgatca tctgcgtttt tagcatggtc gttccattgt
    57541 cggtgccatg gttaatgatt tcatagcgcc cgataatttc atcttctgtc aaagcatctg
    57601 ctacttgttc attgcctcga tactcatagg gtgctggaac tggccagccc tcctcattca
    57661 tatacattct gttgacccgc acttcatggg cttcggttcc attgttaaag cgcgtatgat
    57721 acaccaagga ccactgacca ttctcatcga tgatcgccga attgtgtccc gctgctcgat
    57781 accccatttg ttgaaacgag aattgatagt tcccaatcaa tttgatacca taattcacat
    57841 tttgttcacc tttatccaag attgggctat ttccttgggc atcaaggtaa ggtccttctg
    57901 gtttttcagc gcgaaatagt cgcatattgt aaccaccttt tgctgctaaa ccaccgtaag
    57961 tgacgaatag gtaataataa tcggttttct catcataaac aatgtaggga ccttctcctg
    58021 attgatgata gccacctgag agtttaatcc caaaatagcg atcaatgatg cgcccatctt
    58081 ctgtagtgct atcttcacca ggatacattg gttttccagt ggctggatca acttccaata
    58141 aaaagatacc gccggaccaa gaaccatagg tcatccatag tttcccttct tcatcataaa
    58201 acaaagcggg atcaatggca tttggcgcat aatcggtgtt ataggtaaga ccggcttcga
    58261 tagaccagtt ttcactaaaa ccacttattt ttccatcttt gatcagtttt gccaaatgag
    58321 tattttgata gtttgtatta cggtcactac catccgttga atctttttct gtaaatccag
    58381 aataaataac tgtgtcagaa tagctgtatg gtccttcaat tgtttttgct acagctaatc
    58441 caatcgctga acgccgccaa gtagaactag ctgagtagta aagcatgtag gctcctttgt
    58501 ctccatttga ccattcataa tcagcattcc agatcacatc tggcgcccaa agactatagc
    58561 cgccttttga atcagcatca tcatatcctg cccatttaaa tgtttcagct agattttctt
    58621 tggtatttcc ataaataata ttgtcttcca ttgattcata ttcgtgagaa aaaggaactt
    58681 cccacgttcg taagtctgat gtttttgctt gagcaagatg tgaaccaaat acatagaata
    58741 attcttgatt ttcctcatgg atagttgtaa ttgaagggtc atggatcgat acccgttcct
    58801 tagatgttgt ttcccactcc ttttgtataa gctgctcggc agcttcccct gtttgacatc
    58861 ccataagaaa aaaactggtc aaaaaaacag gtatcatcct actgatcata tttatttttg
    58921 tagtcatttt tttcctctct ttttcttaag ctttgattac accaggttcg ccaaaattag
    58981 gcagtccatt tttatgccat gtaaatggct gaacatacgc atgtctgttt ggattttcca
    59041 atggatcact ataatcattt ttttctggtc gagcgtgata aactaaaata tcttgctttc
    59101 cttcctcatc aattgtaaat gaattatgac caggaccata aagagaatta cgctcagaac
    59161 ttgaaaacac tggttctttt aatttgttcc acgagtagcc attcaacaaa tcgctctctt
    59221 catctgccca taaaagcccc atcgcatagt tttcatccgt cgcacttgct gaataagtga
    59281 taaacacttt tccatttcta atcaaagcgg cgggtgcttc gtttactttg aagccgattt
    59341 tttcccattc ataataaggg atactcagaa gaatctgctt tcctttcaat gtccaaggat
    59401 tttccatctc tgataaataa agattggaat tgcctggaat atttggatct acttgtgccc
    59461 agacataata caatcggttc ctatgttcaa ataccgtagc atctaaactg aaactctcaa
    59521 attgcgtctt gatttgtcct ttttccaccc actctccttc aaagggattt tctttcgcat
    59581 tttcgattgc aaacatccga tgatgatgct gatcatttct gacttctcca tgatctgcag
    59641 cagcaaaata gatgtaccat tttccctgaa taaaatgaat ctctggtgcc cagatcagct
    59701 cactcattga gccttcggca tgagccgtcc agatgacttt tacttcaccg tcagtcagtc
    59761 ctttcaaggt tttcgcacgt cttaattcga tttcctgata ccctggtttt gatccagtga
    59821 agtaataata tccatcggta tgcttgtata tccatgggtc tgctcgttct aatacaatcg
    59881 gttccaaata attttctgcc ataaattcta caccttctta aaaaattcca ttttccgttt
    59941 ttagtatttt tattgcttta tttttagaca tatacatcgt cgtagctagt aaatagagga
    60001 cgacaccaat cacatcatag atgatcaaat ggatgatgac acaggcgatc atccaacgta
    60061 tcgttccttt gtttatttgt ttgtctcgca tattcttcgc gttgatccaa ctgataacgc
    60121 ccatcaaaat cgttgctaat gcaacgatca acactacttt tgagatcata cctataagac
    60181 ttgattgtaa atattcatac tgattttgat tttgaaacgc tgcgatccct tgttcttcaa
    60241 accaaggata atacccaaac atcgttacga gaccaataca gacatcccag accgcactgg
    60301 cacgtagtaa gtttctttcc agttttcgat tcatgatctt cactatcctt ttattcctgc
    60361 atttaagttc atagattcaa tgaaatattt ttgggcaaat aaaaacagca gtactgtggg
    60421 aataatggca atcaatgctg atcccattaa ctggccaatc atccgataat tcccataaat
    60481 gtcttgtaat aaaagcagcc cagccgtaat tggcatctta ctaacgtctg tgtacacgat
    60541 tactggccat aagaaatcat tccaagagcc agtgaaagaa aagagtccgg caacgatcag
    60601 aacaggtttg atcaacggaa cgataatctc tgaaaaaatt gtaaactcat ctgcaccgtc
    60661 cattcgcgcc gattcatcaa actcaagagg aattcccttc ataaattgtc tgacaagaaa
    60721 aatattcccc attccagcca gtcctggaac aatcatggca agagatgaat tgacccaacc
    60781 aaatgtttcg atgattttat aggaaggaat caaattcaca acaccgggaa acatcgagat
    60841 ccccatcaaa agataaaaga ttcgatcacg atatttaaag cgcgttctgc cataaccata
    60901 agctgtcact gaaacaacga tcacaactaa gacagtgtga gtgactgcga taaacagtga
    60961 attccataac cactgcatga taggcgcagt agaggtattg gttaaaatcg ctatatagtt
    61021 atctaatatc caatttacgg gtaacaagcg aaacccagtg gagacgattt cggtctgaga
    61081 acgaaaagaa gtggcgaagc taaaaatcaa tggaataacc cagatgatac ataaaacgat
    61141 cagaaacaaa tatgcgatga tcatactagg tatatgtttc ttttgtgtat tcatttttta
    61201 cccccttaag tattgcttct atctaaaaga aaatattgaa atacggacac acacataatg
    61261 atcaatccta atatgactgc catagccgaa gccatccctg caattgattc cccttgacta
    61321 aaagccagtg aacggatata catcatcaat acagtcgtgc tttgattggg tcctccacca
    61381 gtcatcatca aaggctgtgc aaagacgtta aatgccccag cagttgtcat cacgatcgta
    61441 tataacagtg gaaaccgaat agacggcaag gtcacgttca aaaatttttg gaacgatcca
    61501 gctccgtcga tctctgcggc ttcataaaga tcttcattga cacccgctaa agctgagcga
    61561 tagatgatca tgttaccacc aatcgctccc caaatgctga cagcgaaaat caagatccac
    61621 gcataaggtt gtcgcgatgc ccaagagaaa tcaaacccaa aaatattatt tacggcacct
    61681 aatcgagagt gaaaaatcag tgaccatatc aaagaaccag ctgatacaga gataagacct
    61741 ggaatatata gaaccgcttg aaaaagtcct ttcagcttca cttttttatg ttgcagtgcc
    61801 gctgcaatca tcaaaggaat aatgatctgt agtggtacca tgatcaaaac aaaaataaag
    61861 gtatttttca aaccattcca aaattgagta tagaaagtgg acgaactatc aaataacaac
    61921 gtcttatagt tgtttaggcc gacccaaaca ggatcagaaa tcaaattcca ttgagtaaat
    61981 gaagcataaa tcccatagac tgttggaatg catacaaaaa taataaagag aaccatatgc
    62041 ggtccaatga atgcaattga agcccagtta atgctctttt ttttcattcc tttcattccc
    62101 ttccaaaaat cagaaagggg ataaaattat cccctttcaa ttatttagcc acttccgcaa
    62161 tcttatcttc tacatattgt tgcatcgttg ctaaaccttc atccaagtct aattcactgt
    62221 atgcaatatc tgtgcaatag acgtctaatg cctctaatac ataggagaaa taaacatagt
    62281 caaagatata aagtgtatct tcttcctctg atgttgaagt aaagaaggat tgaggatatt
    62341 gttgataatc atcactttct aaaatgtctt tactagcgac aatttgtccc gcttttgccc
    62401 attcaatcga attcgtacga acgaattcta agaattgcgc gatgacttct tctttctcat
    62461 cggttctaga ctcactcttc aacataccaa acatatggga agcagcccga tttgttgcaa
    62521 tatcatcaga tgttgaataa atgtttgtga caccccaatt cagcccttca acagcatcat
    62581 gcgcggttga agtccaagta ccatctgtgg acaatagaac atttccacct tggaacatca
    62641 gataaccgtc ttcgccataa ggagtcatta acccagcatc ggttagtgct ttaattcttt
    62701 ccaatgcttc tttcatttcc ggagtattaa cggtcggatt gccagcctca tcagaaatag
    62761 ttcctcctaa attacggatc tgagccaaaa taacccagga aagtaaggca ttgttaacaa
    62821 cataatcgcc ttcgtccatt ttccctgcta atgacatcat ttcatcaaaa gtaacaatat
    62881 tatcgtctaa ccaagaggta acatcatatt tctctaaaag gtcctgatta tagtacattg
    62941 cactcgcatg gatatctaac ggaattgtat actgagtgcc tccaattgtt cctgcattcc
    63001 aagcagtatc taaataattg cctttttgta gctctggttg atgcgaaacc aaaggttcaa
    63061 ccgtatcgag aatattcgaa ttaacaaatt cctctacttt gtaggaatgc attaatgtta
    63121 aatcaggaat accattttta gagctaacga ctgtacttaa ttttgtatac atatcagatg
    63181 tgatgacgtg attaattttg taatctgatc cagactgttc attaaattca tctacaatct
    63241 tgtccatata agcaccatca tcccccgtaa gaggagacca aaaatttatt gtgtattttt
    63301 ctttttctga agactggtaa cgtttaaaac cggcaaaagc aattgcgact actgcaacca
    63361 atgcaccaat aataataagt ttcttcttca tgttcttccc tctttcattg aaattgaatt
    63421 atgacctagc cgaacactcc tatcctcctc atcactattt actatcaatt cgtatataat
    63481 ttcattactt attaccaaaa tttgcaaacg ttttctattt ataaataaat cataacttta
    63541 tttgtaaccg ctgtcaacaa cattttaatt aactttacta gaataattgc tactttaatt
    63601 aataaatata ttaatcaata aacgaaataa acaatgctat ttacacaaat tagcaaatat
    63661 attaacattc aagtaaatca aacagtttaa acggaggcga cacgatgcaa ttagaaatca
    63721 atcaagaagc attacctgtc tatgaggcac ttgccagtaa cgtgcgaatc aaaattattc
    63781 aattgctggc taaaaacaag atgaatgtca aagagttggc acaagaatta ggtttaagca
    63841 gtgcgattat tacggtgcac atcaaaaaat tagaggaagc caaaatcatc aaaacggaac
    63901 gtgtggggca aaaaaagatt tccagtttga gagtggatca tattgatatt aactttcctg
    63961 agaaaatatt taatgccttt gatactagag aaacttcgat tccgatcggt cattatacaa
    64021 attattttgt tgaaccaact tgtggattag cgacactctc tggttttatc ggtccagtag
    64081 atgaacctaa attttttatg gacccgaatc gaatggatgg tcggattctc tggttcacga
    64141 aaggctttgt tgaataccag tcacccaatt tcctttctcc agatgagaaa ctagagatga
    64201 tggagatttc catggagatt tcttctgaat ttcctttttc taataataat tggccgtctg
    64261 acattacctt tagcttaaac ggtatcacat tgggcacctg gacaagcccc ggagattttg
    64321 cagatattcg aggcaagtat acgccagatt ggtatccaga caacttaaat caatacgggt
    64381 tgttgaagac gattcgaatc atggaacatg gaacttatat ggaaggcgaa ccattgtcag
    64441 atgtcacgat caaggatatt cctacctatg aagacacatg gcacttaaga gtcgaggtaa
    64501 aggaagaagc tgaaaatata ggaggctgta cattatttgg caaaggattc ggaaattatg
    64561 atcaagacat caaaatcaaa atgttttaca gctaaatagg aagaataata acatttcata
    64621 cgctgttccc atctttaatg gcttatagag ggcaccttta gctgagaata agacaaaaca
    64681 gaccctctag cttcaattaa gagctagagg gtctgttttt gattttaaaa cttggtttat
    64741 ttcttcaaat ggtagctata ggtgctgaca acgatatttt cacgccaaga caatcgcaat
    64801 cttaaccgca aacttgtttg gttatggaga atattctgcc agcgtctgtt tggtacaaat
    64861 tgaggaatca acacagtagt tgtatagttt tgtttcgctg catttttact tacgatatct
    64921 acataacgga taattggatt ttcaatcgag cgataagaag agtggacgat tgaaaaacgg
    64981 acatctggga aatgcttttt aaattctgct tcgatttctt tttctttttc gacatcttcg
    65041 tctagcgaaa catgcatcgc aacgacataa tcaccgatcg aacgtgcgta attcaacgca
    65101 ccgatattta cccgtgtcac attcccgact aatacaagaa cggtattccc gtcataatca
    65161 tgtagttttg catcattttc taaacgaagc tgttctgcta cttttttata atgatcatgg
    65221 atcttataaa aaatgaacat aacgattggc ataatgatga agaaaggcca aatgtcccct
    65281 aaccgataga caaacaaaat cgcaatgatt gcatatgaga tgaacgcacc cgtaatattg
    65341 gcaatcgatt tgcttaacca tctttttcct tcttttttcc atttgacgac catccctgtt
    65401 tgagataaag caaatggaat gaacacgccg atagagtata acggaatcaa gcgttctgtt
    65461 gagccatgga aaataaacag caatacgatc gaacctagcg ctagtgtgat aatcccattg
    65521 gaatagccta gtcgatcccc acgatcttga tacatgtgag gcatgaattt atcttttgcc
    65581 agattgtatg caagaactgg aaaagcagaa aaaccggtgt tagcagcaac tgctaaaatc
    65641 agcgctgtag caaattgaag gacgtaatac aaaataccat gtccaaagac agctttacca
    65701 atttgagaca aaacagtgac ttctttttca ggaacgatcc cataccaata gttgataaat
    65761 gtgatcccca cgaagaagaa acctaagatc aatgccatca tcgtcaatgt agcagcggca
    65821 ttttttgctc ttggcttctt aaagaatggt acagcattac taatcgcctc caccccagtt
    65881 aaagaggaag aaccagaaga aaatgctcgt aaaatcaaag cgatagaaac acccggcaca
    65941 gccgctcctg gaagtgcagt agcttgcaat ggcacagcac ctgtcacgat attatataaa
    66001 ccaacaacga tcagtaacga gatcacaagg ataaatgtgt acaccggaaa taataggaac
    66061 gatgcagatt ccctcagccc acgaagattc agcatcatca gtagcaaaac gattgtcaca
    66121 gaaatagcga cttgatgacc gtagagtgct ggcaccgctg atgtgatcgc ttcagcacct
    66181 gctgagacag atactgctac tgtcaacatg tagtcgatca ataaagagcc accggaaatc
    66241 aagccagcat tctttccaag attctcactg ctgacgacat atgctccccc gccatgagga
    66301 taagcatgga tgatttgacg atatgatagc gttaatgaaa tcaataaaat aataacaaaa
    66361 gcggcaatgg gtagcgaata ccagatggct gcagcagaca aagcgactaa aacgacaacg
    66421 atttgttccg taccatatgc aatagatgat aacgcatcag acgacaataa tgccaaagca
    66481 gcaaatcggg ttaatttgtg ctcatcattt tcagcagatt ttaaaggctt acctactaac
    66541 aaccttttta agtaatccaa tttctaaact cctttacaca caattttact tcaagtttta
    66601 tagtcgaaaa tttatagtaa acaagatgtt atagtacgct cactgacctt aaaagtcaat
    66661 aaactttaag aaaataattg gaaaaaaaca gaaaaatatc aagcgctttt tcaaacgctt
    66721 taatacagca aaaatctaac atttttttat gggctttttc tttgaattct ataataaaag
    66781 gatagaactt gacttagaaa atcaagttct atcctttttg atatcttaac ttttggaaga
    66841 gagatgtaag gctgctttct acccatcatt cttactactc gaagcatagc gcagttgtca
    66901 caacctcttg ataaacggtg tttaaaagct tgcatctgcg gtaataagcc caaccaaatt
    66961 aaaaacataa gaagctgttt ttatttggtc gttcttatta cttgatgcag agcagctttt
    67021 ttacaacctc ttggtacacg gtgttcaatc agctgaccct cggtattagc tcaaaaaaac
    67081 ggcaaaatat gaggaactat ttttccattt ttttctctaa tactcaggtc aaaacactga
    67141 tttcacaacc tcttttttta atgaaaaata tggctctcat gcgccgcttc tttgaatttc
    67201 gtcatttttt cttcgatgaa cggatagatt gccgttccta cgattccaaa gacaacaaac
    67261 aaaccgatca tgatccagat tgctttcgta gcatttggcc aataaattcc tcctgcagat
    67321 tcccgtaaca agtttaccgc atgagtaaat ggcaagaacg gattgatcat ttggaagaat
    67381 ttccctgaga cttggatcgg atagttcccg cctccgccag agatcgacag tactaagatg
    67441 ataatagcga tccctttacc gacattatcg aataatgcag ccaagacata gacgatcatc
    67501 atgaacgcta aggcgatcaa gacagcaaat gacacgctgt agaccggatt ttggacatct
    67561 actcctagta agaaaatatt ccctaatgta acgatcaagc tttgcgcaat cgccattgtc
    67621 aaaaatgtca gcatacgagc aacgaattgt tctcgtttcg taaaattgtt tcggtctttc
    67681 tttcctaaat agtattctgt cgtagcaaca cttgaaagaa gaacagcgcc gacccacaga
    67741 catagtgcag tataaaacgg ggtgctagct gaaccgttat ttgcgattgg ataaagcgca
    67801 ttggtttgta gctcaacagg ttgtgtaaag aagtcacttt cttttgttgc gtctagtttc
    67861 aataatttga tgacttcgcc tagatcgact tcttgttcgc cttttcggat cgcgtctgct
    67921 gctttttgga taccagcttt gatatttggc cagtcattgt tgatcaagtc cgcagcagcg
    67981 ttcacagctg tttcgacttc tggcattttt tcatttactg ttgtcaatgt accggtgatt
    68041 tcatttttta gtgctggcca atcattttgg ataaaatcag cggccaatcc taatttttgc
    68101 tgaatgatcg gtaattcatt gttgtatagg tctgcccctt cattgatgcc attgacgatg
    68161 gtatccatat ttccattcag cattgtattg gcatcatgga tttcttgtcc aattgcaggc
    68221 atttcttttt gatatttttc taaaattgcc actgcattcg ttacagttgc tttcgttgag
    68281 ctgagaagcg aatcaaagtc gatctggtcc gctttgctca gtgcgccttg tgcagtccca
    68341 atcgtatcga tgacttggtc tagtagagaa gtgacagtgg aactgatttg acctgtattg
    68401 ataccagcaa tgatgccatt gatattatta acaacggcat caatttgatc tagcaattca
    68461 tcaatagcct tcgtgtcttc attttgaaca gctgtgttca aagcagatag gcggttttgc
    68521 agattgctta gcaagggttt taattgattt agctgatcaa taattggctg taatttcgta
    68581 tttccagcac ttgtttgcaa tttagtcagg aactcgacca gtttatcgat tgcattttgt
    68641 tgttgagata ttccgtcaat aaagccgttc aatacattgc tgatgttttt cttttcatca
    68701 tcagtcagct taccatcttc aatagctgtt cttacagtat ctattaacga acctgtcgtt
    68761 gttgccactt gtccaattga cttcaatgta acatctacac tgtttgtgat gcttggtatc
    68821 gcatctttca gctgagaggc acctgatttt gtttggtttg ctagatcact tgcctgattt
    68881 tctaaatttt tcacatctgg caagatatct tgtacttgtt ggatgatcgt caagccttgt
    68941 tttgcttcat cgattccttg gttcattgtc tcttggatcg aagcaaaatc gccgtcgatc
    69001 tctgctagtt gcttaccggc attttggatc tctgggattt tttcttgcaa atcaaggatg
    69061 atttttgctt gatctttcaa ctcaggcatt ttgtcattca atgcaacgac tttttcaccc
    69121 atctcatcta ctttagggat gtaatccacg aattcatttg ctttattcag tttttccttg
    69181 atttcaggta gttgactttg taattcgagg acttgttttg tgtagccgtc gatcgtgtcc
    69241 aaattttcat ctgttgataa aatcatatct ttaactttat tgatacttac taggttcgta
    69301 tcgatgtcgt aacctatctc attgaatact ttcaataaag tcgaactggc tgttttgata
    69361 aattcatttg tgatttgcga ttggatcgaa cttgctcctt tatcggtgat tttcggtgca
    69421 atcgcattga ttttttcatt taccgtatat tcgatttttg gtttcttgat atcaccacta
    69481 gtaaaactca gcagatcttc tgagaaatcc tttggcaagt aaatacctgc gtaatacttt
    69541 ccggaacgga ctccgtcttc taattgttct tttgaatcaa cgaattgcca tcctaattgt
    69601 ttatttttat gaagcgattc gatgacttgc tccccaatgg ccacttcttt accttgaaac
    69661 tctgctggct tgtctgcact gtaaacagca attggcagct ctccagtatt tccatatgga
    69721 tcccataatg ctttgatgtt aaaccacgca tatagcgaag ggatgatcat gatcgcgatg
    69781 atcagaagtg ttgcaatcgg gtttttgaaa atccgtttcc agtcaagcaa atataatcga
    69841 agcgtatttt tgattgactg catagttctc ccccttcttc ttttttcagc tgaattactt
    69901 taccatgtat ttcatacttt tttcaatcgg cttttttcaa aaaagtcgaa tttttggaca
    69961 tatcacggca attgtctcat tgtaatctct tacatattga gaaataatta aggattacag
    70021 cctttacttt atcatgaaat aaaagggaaa gataatttta tgccaaagtt tttatctatt
    70081 atacgtatac gcaaaaaagc taaaacattt tttgtctttg cccctacaaa aatgtttcag
    70141 cttttttcgt tttttattcc tgtatttctt atttttcgaa tgacaggatg attttcccag
    70201 caggaggatg tccttcaact agctgatgtg cttggatgac atgcttaagt gaagcagaca
    70261 gattcattga aataaaaaca tgaaaggctc ctttttggta ggctttgatt atgccagcaa
    70321 aggcttctgc atctagatat tcctttcttg gaacaaacga ttcataaaag ccttcctttt
    70381 tttgccgcaa atctagatct gggaggtcat ttaatgcaac atacctgccg cctggtttca
    70441 tgatctggat gccggtttct cctttgatac ttcctttcgt cgcatcgatt acaaggtctg
    70501 cctgatcagc aaattgcaga cctggatttg ttttatcata agcagcaaat gctgaagctc
    70561 ctaatttttt taccttttcc tcatttttac tggatgcact ggttaagatt cggattccct
    70621 tttcatggag aagctggatc agacttgacc cgaccgcacc tgatgctcct agtatcatta
    70681 cagtatctgt cggctggatt tccgtcaaat ggttgattag attataagcc gtaattcctg
    70741 gcgtgaccat tccggctgct tcttcccaac tcattttatc tggaattttt gctacttttg
    70801 ctgatggcaa cacgacttct tctccgtaag tcccgccgac tgcatggaca gctactcgat
    70861 cacctacatg aacagttgtg acatctgaac caatctctgt cacaatacca gcgccatcat
    70921 tacctggtac ataagggaat ttcaatgttc gtatctcttt catttctcct aaacgcaagg
    70981 caacatcata aggattcaca ctgaatgctt ttatttctac acgaacatgt ccagaaccga
    71041 cttctctggg atgagcatcg atttcttcaa aaacatcttg tgcttctccg taaccgttaa
    71101 ttgcaaatct tcgcatggtc accatctccc tttttcttta agtttacgtt tatgccttta
    71161 ttttgacaaa aaaaatgtct tttcgttttg gcgcatgatt caaaacaaaa tagttgtctt
    71221 ttttcgcgta acgtgttaaa ttatttatct aaaagcgtaa agattacgat ttacgctaat
    71281 aaaaaataat tggaggaatt tgttgatggc taaaaaatca aagattgcca aagcaaaaaa
    71341 acagcaagaa acgattgaac gctatgctgc tttacgccag gaattaaaag cgcaaaaaga
    71401 ttacgaaggc ttgcgtaaac ttcctttaga tgctcgtcca gaacgattga aaaatcgtga
    71461 tttaatcgat ggacgccctc gcggatacat gcgtaaattc gggatgtccc gtataaaatt
    71521 ccgtgaatta gcacataaag gtttgattcc aggagtaaaa aaagccagct ggtaatccaa
    71581 gtctggctgt aatgtaaagg aggagggcgc atggaccact ccttggatca tcaaaaaaga
    71641 tacgttcgct tcttctagca gaaatgctgg tactagaagc agacgtatct ttttttacgc
    71701 acagctggtc cttttttata tgtaaaggct gcatggttac ttcgctatat ttatttagta
    71761 acaggagtca gtgcttcgat acccacacta attttcaatg ctcggtcaac ttctgccata
    71821 atgggtcgat ccaaatggca gaccttttct ttcaatcttg atttatcgat cgttctgatc
    71881 tgctccaaca ggataacgga gtctctttct attcctgttc cagtagcttt gatcccaatg
    71941 tgagtcggaa gcttaggttt agccattttt gccgttatgg ccgcaacaat gatcgtcggg
    72001 ctaaaatggt tacctagatt attttgaata accaaaactg ggcgtgttcc gccttgctcc
    72061 gatcccacga ctggagaaag atcagcaaaa taaatatctc ctctttttac cataggatcc
    72121 tccttattct tgatattctc ttggtatccg ctgtcctaat ccgcaagcca cttcatagtg
    72181 gatcgtacct aattgatctg ctatatcctg catagtgatt tctttgtctg catttttgcc
    72241 gataagcgtc acttttgttc cgacaggaaa ttcttgaggc aatcggatca tcagttgatc
    72301 catacataca cgcccaatcg tttcacagta gttcccttct accaatagag aaaaaccctg
    72361 catctttcgt ggccagccat ctgcataacc gatcggtatc gttccgatcc actctgcttc
    72421 aggagtgata tatgtttctc catagccgat tccttcacct gctgggagtt ttttgacttg
    72481 aatcaattca gaaaccagct caagtgctgg ctgcaatgga taaacttccg gtagtgcgtg
    72541 cccagaggga ttaagtccgt acattgctac tccataacga atcatattgc cgattgtttc
    72601 atcatgccat aaagccgttg cactattgct gacatgtaca tatcgaggaa gttcgggaag
    72661 ttttttcagc acttctataa agcgttcttt ttgcagattc caatatgtat catctgcctg
    72721 atctgctgta gaaaaatggg taaataaacc ttcccattct aatacacgac tttctttgat
    72781 gaatgcagct gcctctttta cttcttcagg tgtacaaaat ccgatacgac ccatcccagt
    72841 gtctgctttt agatgaatcg aaagaggcgt ctctagctta cttttctcta aaacagcagc
    72901 tgctgcttgc aaccattccc gtgtacctgc agttactgat aaatcatgag caacagctac
    72961 agtcagtgcg tcgtaaggaa ccatattcaa gataaggatg ggctgagtaa atccagcttc
    73021 tctcaactcg actccttcat ctaaatttga aacacaaaag cccgaagctc cacctgcaac
    73081 tgctgcctca gctgtttcaa tagctccatg accgtatccg ttcgctttta ctactgcaaa
    73141 caattctttt ccttgcggaa gtcttgcaac ttcatttgct acattttcag ttatagcttt
    73201 tttatgtatc actgctttcg ttgggcggtg ccaagcgaca accatcgttt ttccttcttt
    73261 ctagtcttcc aaaataattt gtgcaaaagc tgtttcattt gtatgagtaa tactgaccca
    73321 tacattgcct tcatgaggtg aacgcgtcac aacaggctga ccattttcat tttttaaaat
    73381 ctcgacatct tgaaaggtaa cttttccgat cccagttccc caagctttag agaaagcctc
    73441 tttgcaagcg taacgcccgc ctaaaaattc tacttggcga tgaaaaggca aggactggaa
    73501 tagtttcatt tcatcagagg tcaagattcg tgcaatgaat tttggttttt cttcgatcag
    73561 ccgagtgatc ctaggaagtt cgactgcatc gatcccaatt ccttttatca tatgcttttc
    73621 tcttttcaat aaatttagaa cactctcatt ctaccaaatt ataaccattt tgccacaaat
    73681 aagtccacaa ataacaaaaa tgaaagtttc tcttaaaaaa gagaaacttt cattttatgt
    73741 ttaatcgtta tttgaacgga ttacaaatcc gcgtttttta tcattgtgac gtttaccgcc
    73801 atctttttgg ctgttattat ttttgctata accgcctttt gatttgtttc cacgataatt
    73861 accgccgtca cgacgattac ggttgtttcc gccaccacgt ttgccatttt tattgtatcc
    73921 ttttttctgc attggcaatg ggcgttctgg tgtgatcttc actggcactg catcagctgg
    73981 atcttttgct gtcgttttta gcaaaagtgc aactaaatct tgtgcagaat attcttctaa
    74041 taatttatct gctgtttgca ggtatttatc tagaccattt tctgcaagtt ttgtttcgat
    74101 ttgttcaact gcagcaccta attgaccttt gaatgcttct ttttcggttg gtggacgtaa
    74161 agtcgtcatc cgttttttcg tcaagttttc aatcacatgc aagtagtcca tttcatttgg
    74221 tgtaacgaaa gtcacagaca taccgccttt tccggcacgg cctgtacgtc cgatacggtg
    74281 aacgtagctt tctggatctt gagggatatc atagttgtac acatgagtga cacctgaaat
    74341 atctaatcca cgtgcagcaa cgtctgtcgc tacaaggata tctaaatgac cgctcttaaa
    74401 tgaacgcaat acgctcattc gtttttgttg agacaaatcg ccatggattc cttctgcacg
    74461 gtaaccgcgt gcttctaatc cgcgtgccaa ttcgtctaca cggcgttttg tacgtccgaa
    74521 gacgattgtt aattcaggtg tttgaacatc aaacaagcga gtcatgatat cgaatttttc
    74581 gtattctttt gcgcggacat agtattgatc gatcaagtca gctgtcattt ctttcgcttt
    74641 gatcttcaca tgatgtggat ttttcatgaa tttaacgcca atattcttga tagctggcgg
    74701 catcgttgct gagaaaagta atgtttgtct ttgatcagga acttgtgaaa tgattttttc
    74761 gatatcttcc aagaagccca tattcaacat ttcatctgct tcatccaaaa ctaatgtttg
    74821 aacggttcca agtttcaatg tgtggcggtt aatgtggtca agcatacgtc ctggtgtacc
    74881 cacaacgata tgtggacgat ctttcaagcc acggatctga cggccaatat ctgctccgcc
    74941 gtaaacggct tgtacacgta cttttttgtc gcgccctaaa cgatataatt cttcttgtgt
    75001 ttggatagct aattcacgtg ttggtgcgat aactaaacct tgtaattcgt gacgatctgg
    75061 atcgattttt tctaacattg gtaatccaaa tgcagctgtt ttccctgtac ctgtctgtgc
    75121 ttgtccaata acgtcttttc cagctaatgc tagtggaatc gtttctgctt ggataggcgt
    75181 tgcttcttca aaaccagcgc gttcgactga tttcaacaat tctggtgata attctagttc
    75241 tttaaatttc aaatgaatcc tcctatatgg ttgttaactg aggatgtagc ttttttgcta
    75301 ccccgtcgat ttgttcggtc aaagtgtatt gtttcttttt gacagtggcc acgcacgttt
    75361 ttatccattc ttagcccctg tggcaccacc gaaaaatcac tttgcgaagt ttaggcatta
    75421 gaaaagccaa acgggtcgcg ttcagcttta tcattattat gacatctggc ttcaacaagt
    75481 tgtttctatg gcaaaaccag tccaatttct cttcatcttt cggcaatagg ttattctaac
    75541 atagtttttc gttttctgca agtttacaga tttttatttc atttgctgaa gttgttctac
    75601 cacttcaaat aagcccatgc tgttgctgcc ttttagcata atactatctg ttgcttcaag
    75661 attttgtttg atagcatcaa tcaatttatt cttttctttt tcaaaataga acacaggtag
    75721 ttgggggtat ttttggttca attcttcttt tagtgcatgc atttgttccc cataaaggaa
    75781 aatcatggcg aatttctcag gatcgatatg ttcactcatt tgcgcatgca tatttaaaga
    75841 ctctttccct aattccagca tatctgctaa cacagcgatt ctgcgtcctt ttgttggcag
    75901 atttttaaaa gtatctaata ccagtcccat ggctgttgga tttgcattgt agacatcgct
    75961 caaaatagct gcaccatttc ctgccgttag ccattcggtt ctgttttgag tgatagaaac
    76021 atgggcgagc ccttggcgta tctcaggtat ggacagtcca aagaagcgcc cgatcgtata
    76081 cgcaatcaaa gcattcgtta cattataact tccaggcagc gggatcgtaa atgtttctcc
    76141 ttctactaca aaatcggttt gtgcttttcc ttttgctgtc acttccgcat gaacatcgcc
    76201 atttccaata ccgaatgttg tgactgtttg tactaatgtt gccgttaaag gtgtcagcaa
    76261 cggttcatct gcgggcacaa cgagtaatcc gtctgataca agtccgtcag tgatttccat
    76321 tttggcttta gcgattcctt ctcgcgaccc aagattttct atgtgtgctt caccgatcat
    76381 tgtgattgct gcagcttttg gttgagccat aagtgaaagt tccgtgattt cattggcgtg
    76441 atccatgccc atttccaaaa cgatcttttc tgtatcttgg ggcatgtgca aaatcgtgta
    76501 aggaagacca atattattgt tgtaatttcc ttgcgtctta tatgttttgt atttttcaga
    76561 caagacagac gcggttagat ctttcgtggt ggttttacca ttgcttcctg taattgcaac
    76621 gacttctgcg cctacttttt ccaagtaata ggttgccaat tgctgcatgg ctttcaaagg
    76681 atctgctaca ggaataactg gaaaattttt tggagcttgt tcaacaggca agctccaaaa
    76741 tgaagcagat gctccgtttg tgatcgcttg ctggataaat tcatgtccat ctcgcgtacc
    76801 agcaagagga acgaataaac ttccttcggt tatcttccgg ctgtcaaatt cgacattggt
    76861 aatctttgtc agtgcagagc attcgctgcc cacggcttgt gcaatttctt gtattgttag
    76921 attcattgag atctctccta aaaaaggttg tgaaaaaagc gtttggccta aacggcgggt
    76981 tcgcatgact ctcacttcca agtaaatttc tctattcgta tttagaagct agaatgaacg
    77041 cggttacgca atcactccag cctcttcttt atttctcttt attcattttt ttcaaaaaaa
    77101 gattgacgct gatggtatcg attcattcct aactggatca gttcttcaat caaatcaccg
    77161 tatttcaagc ccatattttc ccataagagt gggtacatac tgaactccgt aaatcctggc
    77221 atagagttta attcattcag gaataattca tttttatttg tcaaaaagaa atcgcaccgg
    77281 ctcaatccgc ttccacctaa catcgtgtaa gctaacttcg cgtactcttg cgctttttga
    77341 taaacttctt ctggcacttc ggctggaatc tgcatttcga ttttattatt gatatatttt
    77401 gcttcataat catagaatgc tacgtctttt acgacttcac caggcaaagt cgtccgaacg
    77461 tcttcatttc ctaatacagc aacttcgatt tcgcgcgctt caattccttg ttcaacgatt
    77521 gctcgagaat catactgata ggctgttgct aaagcatttt gcagctcttc tcggttttct
    77581 gcttttgtaa tgccgacact agaacccata ttcgccggtt tgacaaacat cggataaagc
    77641 aaagaacctt cacattgatc aaatactttt ttaggatttt ctttccattg attcttaagt
    77701 actggtacat aaggaacttg cggcacacca gcagcttgta aaatatactt ggtcatgatt
    77761 ttatccatgg cacatgcact ggtcaatacg cctgcgccga cataaggcat attcaatgtc
    77821 tctaagaagc cttggatcgt tccatcttcc ccgtttggcc catgtaaaac tggaaaaacg
    77881 atggctcctt cttctttgat ttcgcccgga ttgatcactt ttcctgtaaa gccttcctct
    77941 gtctgtccac ttgggtccca tgaaagatgc aagacatctt tgctggcagg tttttctgtt
    78001 agtaatggac ctttgaccca ttgtccttct tttgtaataa atacgagttg aacttggtaa
    78061 taattataat aaatggcatt taaaactgaa aatgcggaaa gaatggacac ttcatgctct
    78121 gcgctgcgtc cgccatatag taaagtaatc ttcaaaagat tgtcctcctg tattctaaat
    78181 cgttcagtga tttactctca tattttagca caaaacaaaa ataaacgaat aacttattta
    78241 taaaaaaacg agccagcttc taaaagaacg agcgtcattt attttttgtc agctagatta
    78301 tttgtcccgt tttttataaa aagttatgat aaagaaaagg agggatgatg atggcgcaaa
    78361 caaatccacg cagccgcttg gcagaaatca ttcgagtgtt catcaattac aatgtagtgc
    78421 caaactttgt acagcaaaaa aatcccgaac aggtaaaaaa agcctttgaa gaactaggcc
    78481 ccaccttcat caagatagga cagatgcttt ctgttcgaga agatttgctt tcttctgcct
    78541 tcactcaaac attcaaaaca ttacaagata gtgtacctag cgacacattt tcaacggtca
    78601 aaaagacgat cgaaacagaa ctttctcttt cattatcaga tatattcgat gatttttcaa
    78661 aatcgccttt tgcctctgct tctatggggc aggctcatcg tgccaagctg aagaacggtg
    78721 acgcggtagt cgttaagatc caacacccta acatcgccga agagatccga cttgatcttc
    78781 aactatttga acgagcgatc cctttgatca aatacattcc tgaaactagc gtagttgatc
    78841 taaaaggggt actccaagaa gtaaaacgtt ccttgatcaa tgaaatggac ttcttaaaag
    78901 aaagtcaaaa tggcgaacaa ttctatcaaa agaacaatgg ctggaaagag atccgcagcc
    78961 ccaagattta tgacgctttt tgttcgaaaa aagtgatcgt gatggaagaa atgtctggta
    79021 aaaacttgaa tcatttaatg aacgccgaaa acaaaactga aacttttatc actggaattc
    79081 aaaacaagca gctgaaacaa gaagttgcaa agcttttagt tgagaacttt atgaaacagg
    79141 tgtttgatga tggttttttc catgctgatc ctcatccagg gaatctgcta ttccatgtac
    79201 taacaaaaga agaacagaca caagctagcc gaaaaactga aacagtccat gaaaaagagt
    79261 tcggttcctt tgcttttcga gcctccactt ctgcagaaga ccctgttgcg ccatatacca
    79321 tcaactacat cgattttggt atgatggggc atctttctgc aggacttagg caaaaactca
    79381 cacaagccgt tttagcgctg tatacgaaag atgcttatcg aatcgaaaaa gcggtccttc
    79441 gactttgtca gcaagaaggc tcgtttgatg aaagtcggtt ccaccaagaa ctgacaagtt
    79501 ttcttgaaca gtattatgat tctcctattg atgaaatcaa cttgcaagaa gtattcacac
    79561 atgtcgtgac gatttgtcat caaaataatc tgcagttcga tcgtgatatc acgcttttgc
    79621 tgaaagcatt tgggacatta gaaggggtga tccgcgtcct cgatcctgaa gtttccctca
    79681 tggaagtcgc ttcgcctttt gctcaacatt attttctcac tcatctggat gtagaagata
    79741 cattgaaaca aagcggatta gacttattgg aagggatgaa ggctgcgcct aagatccctc
    79801 aacagctcca ccatctatta gaaatgtgga cttcgggaca aggaaaagtc aatttggaat
    79861 tgaaaaagca agacaaatta ttgagcagga tcgaaagtat gatcaatcgg cttgttttcg
    79921 gtatgatttt agctgcattg atcgtagggt cctccctgct tgtccaagca gcacctgtag
    79981 aaaacgcaga ggtcgtttcc ttattaggga tatttacgta tgctattgcc gcattcgtca
    80041 ttattttttt ggcaatcgat gcattgatcc aaatgtataa gaagaggaaa aagtagaaaa
    80101 aggttgtgac agaaagaatc agcttcaaga aataagaagg ggttttacat aaattgtttc
    80161 tcaaattttt gtgaaaattc ggcttatttt tcgaagaggc tacttctgaa acaccgagaa
    80221 taaaaaatgt gaaaaagctg ttctgcaccc agtaataaga acaatcaaaa agggaacatg
    80281 gaacacattt atcctgtttc cctgttccct ttttgatgta ttcgagcata aataaaatac
    80341 cttcgttacc tactatcttc tgtacttggt aaaccttagt caattgcctt ttttaacgct
    80401 tgacgaaaag acatatgatc tttctccgta aagggttttg gaccctttgt ccttatgcca
    80461 gcttttctta actttccact atgataacgt tgttctagaa gcgtgccgat attcgcttcg
    80521 tcaaattctt ttccagagtg atggaacact cgcacaccct tcggcaatac aagtgaagct
    80581 aaaccataat cttgcgtgat caaaaagtca ttcttcttaa ccataccgac gattttataa
    80641 tccgcactat cagctccgcg gtctacgtag acgatttgga catgattagc gtattctttg
    80701 gtcgtataat ggtccacact ggtcacgata accacgtcaa gaccatagga ttctcctaat
    80761 tttatgacat cttcttttac tggagaacca tctccatcaa tgaatagcct cattcttttt
    80821 cgccttcttc cataaatgat aaacagttac taatccgctc agtaaaagac caacattgat
    80881 ccattttgcc aagataagca gttgtacact ttctatcggc actgattcat ggttcagcgt
    80941 gatcaataat agatggattg gctctcccat ttcttttgct aaaacaaaca aaagcgtcat
    81001 caataaaaac tggtggatca cactcccttt attttgagta gtatacttga caacgatccg
    81061 gcgatccatt ggaatagctg tatcagtttg ataatattcc ttatttagcc agctgcctgt
    81121 tactacgtgc cagaaactaa gcagaaagac acctatcgca aaaccatttg gaatcaagag
    81181 gaccaataaa gaagaactca gtccaagcaa ttgcatagcc aatggagacc atgttaaacg
    81241 tttcaaaatc catggtccga ctatttttgc tgcaatcaag cctgctgcat aaggcaaata
    81301 cataaaaatc gaaagttttt ctaatccgta cagtatgcca acataaaaac tgctaaataa
    81361 aaaaaggaaa ttccctagca ttccatttag aaaagtaaac agatttagcc agcttggcaa
    81421 cttccattcc ttcttctggt gtcctaaaac aaacacgaac aagatgaaca gcagcaagaa
    81481 accataaata gcaagatcaa aaagcctttc atcgaataac aatcgggcat ttctcaaaag
    81541 aaacaataag ccaaagaata tcaaaaataa aacaagctct cgcgtagcta ccagatttct
    81601 tttgatgtct ttgaaatcca gttcgtaacg cggataatga ctaaccgtat ggtaggccat
    81661 gacgtaaaaa agtgtataaa tagtaaagct tgctgcaatc tgagtcggtg caggcaactc
    81721 aatcgcttga tacaggagaa atagccagat agctgcaaat aagtactttt tcccatccat
    81781 attgataaaa ccttgcgtct tttcgtgaaa attgaccgtg gtattagcag gtacaagcca
    81841 tgctgcactc agccctagca aaacacttga aaaataaaat aaaggaaaat aaaatacgcc
    81901 taatattcca agcaatgaac cagcaccacc aatcagcaga gcgatcatca gcaacgtgta
    81961 actatctaga ccaaatcgta gactgttgac taaaaatagt ccagtcatcc gaaaggcata
    82021 aaacagcgta aatggcaaaa tcgtcagcca attatgcgag tctgttagtc ccaaaaataa
    82081 aagataagga ataaaaataa ccgtgttact taagataaag ggcgttgttt gtgtaaaatt
    82141 acgcccaaat cgtttgagtt tttcgaacat gacaatggct ccttaaacag tcttataact
    82201 aatctgctct tcgattttag cattaaaggg gaaataaacc aattttacag aatatattct
    82261 tgtaaaaaaa aatacagaaa gaagcataag cttctttctg catttttacg gtacttgatt
    82321 actcaagcag acaagccctt ctccacaaaa gtcttgcccg acacccctgc atccggcagg
    82381 tgataaagat agaaatcaat tatcctgtgc ctccaaaatc aattaggagc tctgtaaacc
    82441 agagtccttc tcgacccgtc gcataaattt actttaacac agttcctatg tttatgcgag
    82501 agcttttttc attttataat cgaccatttg aaatccttga ccgatatctg aaataagttc
    82561 ttctgtaatc tcaaatcctt catgcttata aacctcgatt gcttgatgat tcccctgatt
    82621 cactcgcaaa aagatctctc tttcctttgt ttgcgcagca agttcttcat accagcgaaa
    82681 aactgaagaa gtcaatcctt gaccacgtac tttatttagc aaatataatt tacttaaata
    82741 aatttttcca tttatctctt cataagcagt gtaaccgaca gtcttttctt cgctttttaa
    82801 taaaaagtag gacacacctt ctgtcagttc tttttgaatc tgtttttttg actgataagt
    82861 tttcagcatg taatccactt gtttttgacc aatgatcggc acaaaaactt ccggccatac
    82921 ttcttgtatg actgccatca gctcatccag ttcattttct gttactttta ttttttccat
    82981 acacccacgt ccttttttac attataaatg accttgcgct tgatggaata aaaagagcat
    83041 gatcatgcta tacacaccca ccgaccacgg tttcaagaaa atcacaatct gcataaattc
    83101 cctaaaagat aatttcgtca aaccagctac tagacagatc aagtcgtctg gcgcaaaggg
    83161 aagcagcaag gtaacaacta gtactttttt aatatctttc gtttttcttg tcagcaattc
    83221 atcaaatttc tgatactttt ttggcgataa aataagctgg acaaaggcta cgccatagta
    83281 acggacaagc aaaaatccga ttgcttcccc aatcactagg ccaatacaac tatataaaag
    83341 cccaaatcca ttgccaaaca tcagcatgcc cgctactgag gagatccctc ccggcaaaat
    83401 aggaatgatc acttggatca cttgcaacag aacaaatatc atcactgcat acttgccaaa
    83461 ttgctggata aacgcttgca aagacgtgct cgatcgaaaa atcccatgat gataagcata
    83521 aagaatcaac acaaagaaaa aaaacagacc aataatgggc atgatctgaa gacatttttg
    83581 taaaactgat ccttttttag acatctatat tccccacatc ttttttcatt tattaaaact
    83641 gcctcct
//
LOCUS       DBBGSZ010000009        79442 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.009, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000009 DBBGSZ010000000
VERSION     DBBGSZ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 79442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79442
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.009"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            318..1187
                     /locus_tag="ACIZE5_000880"
     CDS             318..1187
                     /locus_tag="ACIZE5_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC6108042.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMINFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1396..2421
                     /locus_tag="ACIZE5_000881"
     CDS             1396..2421
                     /locus_tag="ACIZE5_000881"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGC6108043.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2460..3410
                     /gene="manA"
                     /locus_tag="ACIZE5_000882"
     CDS             2460..3410
                     /gene="manA"
                     /locus_tag="ACIZE5_000882"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HGC6108044.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            3504..5207
                     /locus_tag="ACIZE5_000883"
     CDS             3504..5207
                     /locus_tag="ACIZE5_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC6108045.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5209..7242
                     /locus_tag="ACIZE5_000884"
     CDS             5209..7242
                     /locus_tag="ACIZE5_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HGC6108046.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7253..7693
                     /locus_tag="ACIZE5_000885"
     CDS             7253..7693
                     /locus_tag="ACIZE5_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC6108047.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(7893..9020)
                     /locus_tag="ACIZE5_000886"
     CDS             complement(7893..9020)
                     /locus_tag="ACIZE5_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6108048.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLLDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(9023..9700)
                     /locus_tag="ACIZE5_000887"
     CDS             complement(9023..9700)
                     /locus_tag="ACIZE5_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGC6108049.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9964..11730
                     /locus_tag="ACIZE5_000888"
     CDS             9964..11730
                     /locus_tag="ACIZE5_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HGC6108050.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11745..12182
                     /locus_tag="ACIZE5_000889"
     CDS             11745..12182
                     /locus_tag="ACIZE5_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC6108051.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12195..13346
                     /locus_tag="ACIZE5_000890"
     CDS             12195..13346
                     /locus_tag="ACIZE5_000890"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HGC6108052.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(13408..14106)
                     /locus_tag="ACIZE5_000891"
     CDS             complement(13408..14106)
                     /locus_tag="ACIZE5_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HGC6108053.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(14099..15451)
                     /locus_tag="ACIZE5_000892"
     CDS             complement(14099..15451)
                     /locus_tag="ACIZE5_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurT ligase domain-containing protein"
                     /protein_id="HGC6108054.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(15674..17074)
                     /locus_tag="ACIZE5_000893"
     CDS             complement(15674..17074)
                     /locus_tag="ACIZE5_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGC6108055.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            17235..17972
                     /locus_tag="ACIZE5_000894"
     CDS             17235..17972
                     /locus_tag="ACIZE5_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HGC6108056.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            18097..18576
                     /locus_tag="ACIZE5_000895"
     CDS             18097..18576
                     /locus_tag="ACIZE5_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HGC6108057.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            18573..19340
                     /locus_tag="ACIZE5_000896"
     CDS             18573..19340
                     /locus_tag="ACIZE5_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6681 family protein"
                     /protein_id="HGC6108058.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            19570..20139
                     /gene="lepB"
                     /locus_tag="ACIZE5_000897"
     CDS             19570..20139
                     /gene="lepB"
                     /locus_tag="ACIZE5_000897"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGC6108059.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(20243..20845)
                     /locus_tag="ACIZE5_000898"
     CDS             complement(20243..20845)
                     /locus_tag="ACIZE5_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HGC6108060.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            20951..21181
                     /locus_tag="ACIZE5_000899"
     CDS             20951..21181
                     /locus_tag="ACIZE5_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108061.1"
                     /translation="MPISFVKDREEKGKCVREILLDLPEWFGLPESTEKYIEESSKLP
                     LWCEKRKEEYLGFITLSQTSEDTAEIYSIVWE"
     gene            21172..21420
                     /locus_tag="ACIZE5_000900"
     CDS             21172..21420
                     /locus_tag="ACIZE5_000900"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6108062.1"
                     /translation="MGIKKDYHHQGLGTKLFKEAEGYAAKHYKYLQVKTVDEGHYSIY
                     DQTICFYESLGFSRLEVFPNLWDEWNPCLVLVKKLEQK"
     gene            21526..22110
                     /locus_tag="ACIZE5_000901"
     CDS             21526..22110
                     /locus_tag="ACIZE5_000901"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HGC6108063.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            22113..23186
                     /gene="prfA"
                     /locus_tag="ACIZE5_000902"
     CDS             22113..23186
                     /gene="prfA"
                     /locus_tag="ACIZE5_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HGC6108064.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            23179..24018
                     /gene="prmC"
                     /locus_tag="ACIZE5_000903"
     CDS             23179..24018
                     /gene="prmC"
                     /locus_tag="ACIZE5_000903"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HGC6108065.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            24011..24190
                     /locus_tag="ACIZE5_000904"
     CDS             24011..24190
                     /locus_tag="ACIZE5_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108066.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            24212..25237
                     /locus_tag="ACIZE5_000905"
     CDS             24212..25237
                     /locus_tag="ACIZE5_000905"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HGC6108067.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            25428..26672
                     /gene="glyA"
                     /locus_tag="ACIZE5_000906"
     CDS             25428..26672
                     /gene="glyA"
                     /locus_tag="ACIZE5_000906"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HGC6108068.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            26825..27772
                     /locus_tag="ACIZE5_000907"
     CDS             26825..27772
                     /locus_tag="ACIZE5_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase fold domain-containing
                     protein"
                     /protein_id="HGC6108069.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            27906..28535
                     /gene="upp"
                     /locus_tag="ACIZE5_000908"
     CDS             27906..28535
                     /gene="upp"
                     /locus_tag="ACIZE5_000908"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HGC6108070.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(28674..28916)
                     /locus_tag="ACIZE5_000909"
     CDS             complement(28674..28916)
                     /locus_tag="ACIZE5_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108071.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            29037..29109
                     /locus_tag="ACIZE5_000910"
     tRNA            29037..29109
                     /locus_tag="ACIZE5_000910"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:29070..29072,aa:Thr,seq:cgt)
     gene            complement(29228..29866)
                     /locus_tag="ACIZE5_000911"
     CDS             complement(29228..29866)
                     /locus_tag="ACIZE5_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HGC6108072.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(29989..30621)
                     /locus_tag="ACIZE5_000912"
     CDS             complement(29989..30621)
                     /locus_tag="ACIZE5_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HGC6108073.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            30972..31271
                     /locus_tag="ACIZE5_000913"
     CDS             30972..31271
                     /locus_tag="ACIZE5_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGC6108074.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            31766..33931
                     /gene="acm"
                     /locus_tag="ACIZE5_000914"
     CDS             31766..33931
                     /gene="acm"
                     /locus_tag="ACIZE5_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HGC6108075.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(34203..34688)
                     /locus_tag="ACIZE5_000915"
     CDS             complement(34203..34688)
                     /locus_tag="ACIZE5_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HGC6108076.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    34778..35123
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            35168..35809
                     /locus_tag="ACIZE5_000916"
     CDS             35168..35809
                     /locus_tag="ACIZE5_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGC6108077.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            35828..36463
                     /locus_tag="ACIZE5_000917"
     CDS             35828..36463
                     /locus_tag="ACIZE5_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGC6108078.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            36481..37296
                     /locus_tag="ACIZE5_000918"
     CDS             36481..37296
                     /locus_tag="ACIZE5_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC6108079.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            37615..39051
                     /locus_tag="ACIZE5_000919"
                     /pseudo
     CDS             37615..39051
                     /locus_tag="ACIZE5_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            39240..41687
                     /locus_tag="ACIZE5_000920"
     CDS             39240..41687
                     /locus_tag="ACIZE5_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HGC6108080.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            41917..42984
                     /gene="rlmN"
                     /locus_tag="ACIZE5_000921"
     CDS             41917..42984
                     /gene="rlmN"
                     /locus_tag="ACIZE5_000921"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HGC6108081.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            42974..43180
                     /locus_tag="ACIZE5_000922"
     CDS             42974..43180
                     /locus_tag="ACIZE5_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108082.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(43177..44280)
                     /locus_tag="ACIZE5_000923"
     CDS             complement(43177..44280)
                     /locus_tag="ACIZE5_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HGC6108083.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            44832..45380
                     /gene="aac(6')"
                     /locus_tag="ACIZE5_000924"
     CDS             44832..45380
                     /gene="aac(6')"
                     /locus_tag="ACIZE5_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HGC6108084.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            complement(45628..45747)
                     /locus_tag="ACIZE5_000925"
     CDS             complement(45628..45747)
                     /locus_tag="ACIZE5_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HGC6108085.1"
                     /translation="MVFQKPLNNFRYIVYYCHTKIKKNKQKETVTKVLSQSLI"
     gene            45926..47587
                     /locus_tag="ACIZE5_000926"
     CDS             45926..47587
                     /locus_tag="ACIZE5_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC6108086.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(47657..48004)
                     /locus_tag="ACIZE5_000927"
     CDS             complement(47657..48004)
                     /locus_tag="ACIZE5_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HGC6108087.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            48088..49029
                     /gene="opp3b"
                     /locus_tag="ACIZE5_000928"
     CDS             48088..49029
                     /gene="opp3b"
                     /locus_tag="ACIZE5_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HGC6108088.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            49030..50073
                     /locus_tag="ACIZE5_000929"
     CDS             49030..50073
                     /locus_tag="ACIZE5_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6108089.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            50079..51149
                     /locus_tag="ACIZE5_000930"
     CDS             50079..51149
                     /locus_tag="ACIZE5_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6108090.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            51139..52092
                     /locus_tag="ACIZE5_000931"
     CDS             51139..52092
                     /locus_tag="ACIZE5_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6108091.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            52104..53114
                     /locus_tag="ACIZE5_000932"
     CDS             52104..53114
                     /locus_tag="ACIZE5_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HGC6108092.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(53399..54220)
                     /locus_tag="ACIZE5_000933"
     CDS             complement(53399..54220)
                     /locus_tag="ACIZE5_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGC6108093.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(54317..54595)
                     /locus_tag="ACIZE5_000934"
     CDS             complement(54317..54595)
                     /locus_tag="ACIZE5_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108094.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            54863..56872
                     /gene="metG"
                     /locus_tag="ACIZE5_000935"
     CDS             54863..56872
                     /gene="metG"
                     /locus_tag="ACIZE5_000935"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HGC6108095.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(57351..57938)
                     /locus_tag="ACIZE5_000936"
     CDS             complement(57351..57938)
                     /locus_tag="ACIZE5_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108096.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            58113..59435
                     /locus_tag="ACIZE5_000937"
     CDS             58113..59435
                     /locus_tag="ACIZE5_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGC6108097.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            59590..60366
                     /locus_tag="ACIZE5_000938"
     CDS             59590..60366
                     /locus_tag="ACIZE5_000938"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HGC6108098.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            60359..60928
                     /gene="rnmV"
                     /locus_tag="ACIZE5_000939"
     CDS             60359..60928
                     /gene="rnmV"
                     /locus_tag="ACIZE5_000939"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HGC6108099.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            60921..61805
                     /gene="rsmA"
                     /locus_tag="ACIZE5_000940"
     CDS             60921..61805
                     /gene="rsmA"
                     /locus_tag="ACIZE5_000940"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HGC6108100.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            62256..62885
                     /locus_tag="ACIZE5_000941"
     CDS             62256..62885
                     /locus_tag="ACIZE5_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108101.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(63009..64118)
                     /locus_tag="ACIZE5_000942"
     CDS             complement(63009..64118)
                     /locus_tag="ACIZE5_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6108102.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            64327..64749
                     /gene="mgsA"
                     /locus_tag="ACIZE5_000943"
     CDS             64327..64749
                     /gene="mgsA"
                     /locus_tag="ACIZE5_000943"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006007 - glucose catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HGC6108103.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     regulatory      64936..65034
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01831"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="THF riboswitches regulate genes encoding folate
                     transporters and folate metabolism; They are most commonly
                     found in Clostridiales and Lactobacillales; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="tetrahydrofolate"
                     /db_xref="RFAM:RF01831"
     gene            65072..65608
                     /locus_tag="ACIZE5_000944"
     CDS             65072..65608
                     /locus_tag="ACIZE5_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HGC6108104.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(65648..67411)
                     /locus_tag="ACIZE5_000945"
     CDS             complement(65648..67411)
                     /locus_tag="ACIZE5_000945"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6108105.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(67414..69129)
                     /locus_tag="ACIZE5_000946"
     CDS             complement(67414..69129)
                     /locus_tag="ACIZE5_000946"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6108106.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(69908..70132)
                     /locus_tag="ACIZE5_000947"
     CDS             complement(69908..70132)
                     /locus_tag="ACIZE5_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108107.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            70323..73100
                     /locus_tag="ACIZE5_000948"
     CDS             70323..73100
                     /locus_tag="ACIZE5_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGC6108108.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            73181..73600
                     /locus_tag="ACIZE5_000949"
     CDS             73181..73600
                     /locus_tag="ACIZE5_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC6108109.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            73612..74082
                     /locus_tag="ACIZE5_000950"
     CDS             73612..74082
                     /locus_tag="ACIZE5_000950"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC6108110.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            74099..74878
                     /locus_tag="ACIZE5_000951"
     CDS             74099..74878
                     /locus_tag="ACIZE5_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGC6108111.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            74865..75686
                     /locus_tag="ACIZE5_000952"
     CDS             74865..75686
                     /locus_tag="ACIZE5_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGC6108112.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            75703..76752
                     /locus_tag="ACIZE5_000953"
     CDS             75703..76752
                     /locus_tag="ACIZE5_000953"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGC6108113.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            76765..77769
                     /locus_tag="ACIZE5_000954"
     CDS             76765..77769
                     /locus_tag="ACIZE5_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGC6108114.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            78402..79421
                     /locus_tag="ACIZE5_000955"
     CDS             78402..79421
                     /locus_tag="ACIZE5_000955"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HGC6108115.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT        26646 a        13810 c        16215 g        22771 t
ORIGIN      
        1 aaatttttct tactactcga aactaagcga ctttttcaca acctcttcct taaacggtgt
       61 tcaaaagctt gcatctgcgg taataagccc aaccaaacga aaaataggag gagctatttt
      121 tgtttggctg ttcttattac ttgatgcaga acagcttttt cacaacctct ttttataaga
      181 gtttttactc attaatttac aaaaaacaag caaaatgcga attttctcac atttttttta
      241 acaaaatcaa agttattgct tgaaagaaga agaatccatc gttaaaataa agcttgacgt
      301 agaggggagc aagaaatatg aaagattttc aattgggggc tgccacctat ttaaaaagtg
      361 tagccattcg ggtgaaagac cgagataaaa tgattaattt ttacaagaac gttgttggct
      421 ttgatttgaa aagagaagaa aacgaattag ccattttagg aacagaagaa gctggaagtg
      481 aaatgttgct gctggaagaa agtcctagag cgaatgatca catgggggtg atcaaaaagc
      541 tgaaccgttt ttcattgatt atccctagca cagaagaaat ggcagatatc ctttgtcgta
      601 tccgtaaaat gaattatcca atcaaagaag ctttagaaga tcatggacgt atggggattt
      661 tgctcgtaga cccagaagag aatgaattgg aaatttacca tgaagagaat aagaacgacc
      721 aaagagaaat tccagaaaca atggatcaag aagcattatt aagaaaatct gaagaaaaat
      781 tcagtaaact atcaacaggt tcttattttg aaaaaatcca tttaaatgtt actaacttaa
      841 caaaagaacg ccaatttctt aatcatgtac ttggtttgaa ggtacataat gaagaagagg
      901 gcatccatgt attgaatgaa ggagatttcc atgttggttt gacagaagct agcggaggcg
      961 caattgattt gcctacagat gaagtgattg gacttgattt tctgaaattc atgatcgata
     1021 ctgaaagcat ggaaggactg attgctcact tgcagcaact atcagttgat ttcttcttag
     1081 acaaaaagca cacagtactc acaatctatg atgctatagg aatcgaatgg tggttcgtca
     1141 gtgagccaaa agaaaagaat aaaactgaca ttcgatgcga cgcttaactt tttctttctt
     1201 aacgattgtc gcatgtctcg tcattttatg aacggtcata ctatcgctta ttctagagat
     1261 agaaagagaa aatagtatac cgggggaaac tgcgcggttt ttcgcgcagt ttttttgtgt
     1321 aaaaaaggtt gattcctcat agattaagct ttaagcttgg actgtaagaa tctgatagaa
     1381 aagcaggaga aaaagatgta tccacacacg aaacagctta ttttgaaaaa gatggaagaa
     1441 ggattttatc caggtgtagc agtcgccttc ataaaagaaa atcaagtaga aacatttaca
     1501 gccggctttg cccaagtcgt tcctgaaaag cagctgatga cagaagatct gttgtttgat
     1561 gcagcctcac tgacgaaagt cgttgcaacc acttcattag ttttacgtct attagaagat
     1621 ggaaagatag aactcgatca accgcttcat aaatatcttc ctgaatttga aaatcagaca
     1681 atcactttgc gtcatttact gacacatact tctgatatca aaacatggat accaaacaga
     1741 gataagctat ctcaggaaga attgatcgcc gcttatttga agctagaacc aggtgagcaa
     1801 ctaggaaaag aagtaaaata tacagatgcc ggtacgattc ttcttgggtt gatgctagag
     1861 gaaatttacc aagaaactgc agtggaaatc tttcaagaac aagtattgga accattagga
     1921 atgatgaaca gcttatttct tccttttcct tccaaaaaaa tcgttcccac agaacaactg
     1981 ccttcgggtg aggttttgcg tggacaaact catgatccga aagcaagagt tttggctgaa
     2041 catgcaggta acgcgggtct ctttattgat ttgaaagaca gcattacttt tgtccaaatg
     2101 tatttgaaca agggaaaaat ccgtaatggt cgttttttag aagaagagac gattgattct
     2161 ttactgcaag atcaaacacc gaaaaaaaat ggctatcgtt ctttaggatg ggacttaaaa
     2221 aaggatgtag aagacggtca tgcgattctt tttcatactg gttatacagg tacgtttttc
     2281 ttgattgata taaaaacaca agaagcgttg atatttttgt caaatcgcgt acatcctgtc
     2341 gatcatcgtg cggagtatct catatgtcga gatgaaattg ttgaaaactt tttgaaagag
     2401 aaagcggtat taccgaaata atgctataat agctatgaaa aatgagagga gtttgaatta
     2461 tgcaggaacc tatgttttta aaaccagttt ttcaagaaaa aatttgggga ggaagtcgtt
     2521 tacgttcagt ctttggtttt gatatcccta acgataaaat cggagaagat tgggcgatca
     2581 gtgcgcatcc tcatggtgtc agtgtagtag aaaatggcga attcaaaggg aaaagattag
     2641 atgaactatg gtcagaacac aaggaattgt ttggccatcc ttcagaacca gtgtttccat
     2701 tattgatcaa gatcttagac gcagaagatg atctatctgt acaagtacat ccagatgatg
     2761 cctatgggat gaaacatgaa ggtgaattag gaaaaactga atgctggtat atcatcgatg
     2821 ctgaacctgg tgcagaaatc atctatggtc atcatgcaaa gacaagagaa gaactagctg
     2881 agatgatcaa agatgggcgc tgggatgacc ttttgaagaa agtaccagtt aaaaaaggtg
     2941 atttctttta tgtaccaagc ggaacgatcc atgctattgg taaaggaatc atgattttag
     3001 aaacacagca aagttctgac acgacttacc gcgtgtatga ctacgacaga aaagatgcgc
     3061 aaggacaaac aagagagctg catatccaac aatcgatcga tgtaacaact gtccctgcga
     3121 aaacaccaga attacaaatc aaagaagtcc gaaaagggaa ttcatcgatc gtcacttatt
     3181 tagaaactga gtttttcaat gtatatgagt gggatattaa aggaatcaca tctttcaaaa
     3241 aacaagcccc ttatacattg atgacggtaa tcgaaggagc aggagacctt gtcgttgacg
     3301 gaaaaacata tccattagaa aaaggaacaa gctgtattat tccaaatggc gtttctgagt
     3361 gggcggtcca aggtgaacta gcaatcattg cgtctgaacc aggcaaatag ttcccagata
     3421 gctgaaagca gcagacggtt tttcgtttgc tgctttttct acataaaatc cgtccatcaa
     3481 taaatagaag tctggtgaaa aagatggaat acaaatggaa agcaaacaac agcagtcgcg
     3541 tgtctatgaa acaactgaga aaagctggac atcacttaaa tgaaatgatc atgccaaatc
     3601 taagtctgtt tatcgcttgg ggaatcttgt cattagcaac aaaaggtgtg tctggcgatt
     3661 tgcacaccac attagaagag gtatgccatt ggatgatcca gctgctttta cccatcttga
     3721 tcagttattc aggcgggaaa tcggtagggg gacaaaaagg ggcagtcgcc ggtgcaattg
     3781 cttctttagg gttgatcgct cgttccaatg ctccacaaat cgtaggagcg atgattatcg
     3841 ggccgcttgc cggcatcgta tatgaacaat ttgtttctag attccatgtg aaattcaagg
     3901 ctggatatga aatgcttgtc agcaacctac tagtaggact gactggtagc gttatttgta
     3961 taattggaat cgtttttatt gaaccagttt taaatagtgt tcacttgttg ctcgcctccg
     4021 ttgtgtcttg gctagtcaca atgaatctgt taccacttgt cagtctgatc ttagaacctc
     4081 taaaagtact atttttcaat aatgcaatca atcatggtgt attgacacct ttaggaatcg
     4141 aattctcaca aacagtcggg tactcttcct tatttttgat ggaggcaaat cctggacctg
     4201 gtttagggat cttactttct atcctttgtt ttgcagaaaa acaggaaaaa gtaaatgcga
     4261 gtggagcatt gatgatccat gcgattggcg ggattcacga aatctatttt ccatttgtct
     4321 tgctgcgacc gtatctattt ttagctgtaa tggctggtgg ggcaagcggc acgttgatat
     4381 ttcaatggtt agatacggga ttagctgcac ctgtatcgcc tgggtcacta ctcgtgattt
     4441 ttgccaatgc gccttatcca caactagctg gggtaagtat agggatagca atcagtacat
     4501 ttgtgacctt catttgtgca gcgatactat tgaaattacc aaataaagaa aaagagaaca
     4561 aaacggtcaa agaaagggga gaaatcttgg aaccatctat cattcattcc gtcatttttg
     4621 cttgcgactc aggtatggga tcaagtgcta tgggagccgc cctgctgaaa aagaaattag
     4681 cagcagaaaa aatcgatctt tctgtcggat acagctctat ctatgaattg aataaccaag
     4741 taaatcagct ggttatcgtg caacatgaac tagcgggtct tgcaagagaa aaagtacctc
     4801 aaagtcaaat ctatgtactg gatcactttt tggaaacaga tatcttgctg tcacgaataa
     4861 aagaagcgat ccaatttcca aagcgggaag aaaaaaaaga gatagcagat atcacagaac
     4921 aaaaaacgtc gcctgctaat attgtatttt tgtataaaaa caacagacgc ggctcacaaa
     4981 ctatgggcat gacgatttta agtcaattag caaaaaaagc gaaaaaacag tttgttatct
     5041 caaaagaatc aatagaaaaa atcaaaatcc aagaagaaac gatttatatc gcacaaagag
     5101 aactagctgt aactgaacag ctagaagaaa agatccctcg gctagttcta gttgaacatt
     5161 gggtagctac gaatgaatac gaaaaactcg tgaagggaga aatataagat gtatttatcg
     5221 cccagagaaa aacaattatt agcagaattt ctcagtagcc cgtcacctgt atctatccaa
     5281 aaaatgatga atttattgaa ggtcagtaaa cggactattt accgcgaatt agataatctt
     5341 gaagtctcat tgaaatcggt aaatgcttct ttgaaaaaag cagctagagg ctcatttgtc
     5401 attgaggcat cagaagaagt attagagcaa ttaaaagaaa atacagatgg gaaaagtaat
     5461 gacttatcca ctgctaaacg acaacacgcg attttagccg agttgttact gacgacagag
     5521 ccgttgagtc ttgctcattt catggaatca tatcgcatca gtaataccac tttttatgca
     5581 gatatcaaac agttggaaga aagtattcgc caactgcctt tggaaatcat tcggaaccag
     5641 ggatacgaga tcgaaggacc ggaaaaatac cgccggcttc tgacagcgaa tgtattagaa
     5701 ttagaaatca atgaatatga actttttcat agtatttctt tcgatgcatc actgaattat
     5761 ttttttcgat tcgttgatcc gcaacatcta tctcttgcac gcaaagtaat cggggaagaa
     5821 ttgatccaaa aaaagaccaa tctaagtgat agaaagcttg aacatttggt tttgatgctg
     5881 acattgacga tggagcgtgt gacgaaaaat catttactga caaatgagac atataatagt
     5941 ctggcaaaca aagaattact acagacagct aaacgattgt tttcacggat cgcttctgag
     6001 acaaaacaac tttatccagt aaatgagatc gtcttttttg caggattatt aaatgacttc
     6061 acgaactcat ttgatcagaa tttctttgaa gagacgttcg atacacagct tgcttattta
     6121 gtaaaacaac tgattcaaga agtaagtgaa gagacgaatg tccattttta tgaagatgaa
     6181 actttgtaca aaatgctgtt gactcattta tctggtgtgt tttcaagagc cgttttacaa
     6241 gaagagacac tgaccaatcc gattttagaa aaaatcatgg ttcaatacga ggaagttgcg
     6301 aatgcaatcc gtaaagcagt agagcggatt tttcaagaaa aaaaattatc cgaagaagag
     6361 atcgcttata tggtccttca ttttgcgaat tcattggaac gaagtccgaa agaaagcaat
     6421 atcagtattg caggattttc gccaagtgga ttagcttcta ctagcatgtt ggaactacga
     6481 ttgaaaaggt attttccctt catccaacaa attcatttct atcggattgc tgatttaaaa
     6541 aaaatcgatt tacaagaaga atatgatgtt gttatttcta catctatttt accaggatac
     6601 ggtggaaaat atattttagt ctccccgcta ctgctagaag atgaagtcaa gcagctaaaa
     6661 gaagcttttt cgcatattga gaagaaaaaa aggcaaaaaa ttacgtataa cagcaataac
     6721 gagtggatga tagaagatac ttatgaggaa acaatgcatt tcatggatca aatcaatcaa
     6781 ttactcggtc gtttttttat ccaagaactg gataatcctg agacgatttc cgaaacgatt
     6841 cgcagcttat ttccttattt tcctgaagga ctagtaacgg atgaagaggt ggttcatcgc
     6901 cggctgctta agcgatatga acaagcacct atcggtattc ctcatacaaa tatggggtta
     6961 ttccatacat ccagctcatt gatttctaaa ccgatctttt gtattttcaa tttgaaacat
     7021 ccgttgacca ttgaagggat ggatagacag ccagtcgatt tgtcccgtat gttagttatg
     7081 ctggcgcctt cgccaatcca agaaaaagac gggattcttt taggaaagat cagtggagca
     7141 atcatcatga atgacttgaa caccgagatc ttccgctcag gaaataaaga aatcgtttat
     7201 cagttgttag cgaaaatcct gattgaagaa ataaagaaat gaaggtgaaa agatgataca
     7261 gctaccagca gaaaaaatat tgctcgatca atcctatcaa aattggaaag aagcgttgac
     7321 cgagatcggc cagtggatga cccaacaagg gggaatcaaa ccggcatata tccaatcaat
     7381 gatcgaaaga caagaaaaag cgagtgtcta tatcgggaat ttcgtagcct tgccacatgg
     7441 gactgacaaa gatgaagaag tagtagaaga aggaatctat ttagtccaag tgcctgatgg
     7501 tgtggacttt ggaacaaaag aggaaccaaa aatcgcgaca ctcttatttg tagtggcttt
     7561 aaaaaaagaa catcagttag cggtgctcca agatttagcc tttttctgtt cagacatcga
     7621 ccaagtaatg gcgctcagtg atgcggaaac cattgaagaa gtccaaatga tttttgaaca
     7681 tggacatata taaccaatgt tcacagtaaa aaaagctgcc ttgcatcaag taataacttc
     7741 aaccaagata aaaataagag gagctatttt tgttgggagg ttcttattac tgcggatgca
     7801 agcttttgaa aactatttat tctagaaaac cgtttatttg aaatagggga cggtgacaag
     7861 gtttttgtca ccgcccctat tatttttgtg ttttaatagc tcttttttat atagatagtg
     7921 cccataccta tgaataataa aacgatactc catataccaa gtgtcaagat accattcatg
     7981 aaagtaacct gttctgaagc tagtggcgag aaaatatctc ctcctatgat cacattttga
     8041 aaatcaacat aagaagttgg caagtaatga ctgattgatt ctatccatcc aatcgaagaa
     8101 aacaagcgat actctgctaa gaaaagacaa agaagtgtac ctaaaagatt gactagagaa
     8161 tgttcaaata aagcagatag aagaaaactg attgtactta aaaagagcac ccacaacaac
     8221 aggaacagaa agctctggaa aagatactca tacatcggca ggattcgtat ctcctgacca
     8281 atgatcgttc ctacaggata acggaagtct cccaaaccat ttttgattat tactagtata
     8341 gagacgatca aaaatggcat cacgagactt agcatagctg caccataata aatggtaaaa
     8401 cggatgctat gtttctttac catactatcc agtaatagat tgactagaga gattacctgc
     8461 tttctttttt cataagagat gatggaagaa agaaacaagg cggttataca taaaatcaaa
     8521 aaactagaaa tcattcctga aaaaatattt tcgtagtaat ttgctaaaga gagatgcgct
     8581 ggcaagtcaa aaatagaata tctttggatc tgatgttctt tcatataacg gagcaactcg
     8641 acacgttttt gttgttcaat gattggaatt ccttgtcttt gaccagaaat cagtcgatcc
     8701 agtatatctt tttcataatg ataagttgct tcgaccattt gctggacatt ccctgtgttt
     8761 tttgcatgta agattgcttc gatcagtttg ttgcttttct ctaaactttc cacaaattct
     8821 ttctcattct catcttcttt caacgtttca atcaaacgtt gcatctcttc atagttatga
     8881 ttcagttcat cgaattctgt ataagcaagt ttatgatcaa aaaaaagtgg gaatgcaaag
     8941 agcacgacca acaatagagg aaataaaaag tttactttgt tttttagtaa gagattgcgt
     9001 tcaaatgtaa gtaaagacat agttacacct catataattt acgataaata gctaaaatct
     9061 cttccatatt tgaggattct gtgacgattt ctccattttt tagaaaacat gctttagaac
     9121 aaatcgattg gatattcgcg atagcgtggg aagaaagaag aatcgtcttc ccctctttct
     9181 gccattgtct gatgaggcta ttcaagatat caatacttcc tgggtctaat ccgttcaacg
     9241 gttcatcgaa taacatgaca gatgaatcac tgatcaagta agcagcaagc aagacatgtt
     9301 gtttcattcc tagagacatt tttccaatcg gcaaagtaag gtactcagtc atcttcaatc
     9361 gttggaaaac agtttggcat tctactttgc tctgccaata gtatttgatc aaagtcaaat
     9421 aatcaacagc cgatagatag tcggataact gattcgttga ttctagaaaa aagaaagacc
     9481 ggcgataatc tgtataagca gtaggagaga tgttgtgaag ggacaattga tcataagttg
     9541 ttggcagcag ttgggcaatg ccattcagca aagttgtttt gccaaatccg ttcggggcaa
     9601 tcaaagcagc tacttctcct gattctacta aaagattcaa ttgtcgaatc acacgttttt
     9661 taccacgttt catgttcatg tttttgatca gtaatgtcat agataggcct ccaatataaa
     9721 atttaataac ataatagaat ggaaaacatc taaattaaat gctaacaaaa gttattgttt
     9781 gcatattata aaaaaattaa aataacagtt ttatttaaaa ttgaagtttt ctgataccga
     9841 aatcttttta ttttgctgac atactcaaac ctttggcaca aagtttcgtg ccaaagtacg
     9901 actatttctc tttttagtaa gcggatacaa ttagagtatc aaaaggagag agggagagac
     9961 aaaatggaac ggacgattcc caaaaacaac atttcgctaa aagcgagggt acaaaaatta
    10021 ggcagtactt tatcaagcat ggtcatgcca aatattggag cactgattgc ctggggtgta
    10081 ttaacggctc tatttatccc agatggttat ttaccaaatg aggctttcgc taccatggta
    10141 agcccaatgc taacttatct gattccttta ttgatcggtt atactggcgg aaaagtaatt
    10201 gctggtgacc gcggatcagt tgttggggca attgcaacga tgggtgtgat tgtcggaaca
    10261 gatattccaa tgatgctagg cgcgatgatc atgggacctc ttggtggata tgccatcaag
    10321 aaatttgatc agctattcca aaaacggatc aaatccggtt ttgaaatgct agtcaataat
    10381 ttttcagcag gtcttatcgg ttttggatta gcgttattag gtttttctgc gattggtcca
    10441 gttgtcgatg cattgactca agcaatggca aaaggtgtag agatcatttt atctgcccat
    10501 ttgattccat tgacaagtat ttttattgaa ccagcaaaaa tcttattttt gaataatgca
    10561 atcaatcatg ggattttgac accattggga actgaacaag tagcagaggc tggaaaatct
    10621 attctattct tgcttgaagc aaatcctggt ccaggacttg gcgtattact tgcttttact
    10681 ttgtttggca aaggagcagc aaaatcttca gcaccaggag ccatgatcat tcacttttta
    10741 ggcgggatcc atgaaatcta ttttccttac gttatgatga aaccgttatt attcttatca
    10801 gttataggcg gaggaatgtc aggaagtttc attttccaat tgatggatgc tggactaaga
    10861 gcgccagctt ctccagggtc gatcattgcg attctagcga tgacaccgtt caattcttac
    10921 cttcctgtta ttttgggcgt gattgttgcc gcagctgttt cgtttggtat ttctgcagta
    10981 attttgaaag cggatgcgaa agatacaaat gaagacttcg aaaaatctgt tcaagagaca
    11041 aaggcagcta agcaagcttc caaaggtgcc caaggtattc ctcaaggagc tacattctct
    11101 ggcgtacaaa aaatcatttt tgcttgtgat gcaggaatgg gatcaagtgc gatgggcgct
    11161 tcgatcttga gaaaaaaagt acaggaagca gacttgcctc aaacggtgac caatcaagca
    11221 atcagccaac tgacagatga ctcgaataca ttgatcgtta ctcaggtcga actacaagaa
    11281 agagcaaaac aaaaagcacc gagcgcgcgt tttgtctcag tagaaaactt tttgaattca
    11341 cctcgatatg atgaaatcat tcaagaatta agcagcaagc agaaaacatc agtttctgaa
    11401 attgagaatg agccagcaga agagtttctt tcagcaaaca tcaaacaaat caaagagatt
    11461 ctacttgtcc acgatgatcg ttccggatca gcaacaatgg ggatgaccgt gctcaaagat
    11521 atattagaca agaaccattt aactatcccg ttaagaaaag tcaatatcca agatttaaaa
    11581 gatgaacctg attcactgat cgtagccaaa gaaagtttag cggaaaaagt acagatggct
    11641 gcacctcaat ccattcattt atcagtcaac agcatggtca atccgcaaaa atacgaatcg
    11701 attgcacaat atttgaaaca gacagcttaa gggaggaaaa cagcatgcaa agtttgccat
    11761 tcgacatgat cgagctcaat cgatctttta aaaccaaaga agaagcgatc cgctattgcg
    11821 gtcagatgct tgtagaagca gggtgcgttg atgaggaata tatcgatgcc atggtagata
    11881 gagacaaaat gttatctgtt tatatgggga attttatcgc gattcctcat ggaacagatg
    11941 aagcaaaaaa atatgtgaaa aaatccggca tctgtgtcgt tcaagtacca gatggtgtag
    12001 attttggtac cgaagaagaa gaaaagattg cgactgtttt gttcggtatt gcaggagtcg
    12061 gagatgagca tttgcaactt gtacagcaaa tcgcacttta ttgcagtgat atggacaatg
    12121 ttgtccagct agcagacgcg ctcagcaaag aagaagtaac ggaaaatcta gcaattgctt
    12181 aaggagagag aaaaatgaga gcagtacatt ttggtgcagg aaatatcggt cgaggattta
    12241 ttggagaggt tttggcagct aatggatttg agattacttt cgtagatgtg aatcacacga
    12301 tcattgatgc tttaaatgaa agaaaagaat acgaaatcga attagcagat gaatcaaaag
    12361 aaaaaatcac tgtaaaaaat gtcaaaggaa tcaacaatca aacaaatcca gaaaaagtaa
    12421 tccaagaaat cgctgaagca gatttagtta ctaccgccat tggcccgaat atcttacctt
    12481 ttattgctga gttgattgca aaaggtatcc aagaaagaga aaaggaagga agcacaacat
    12541 ctttagatat cattgcctgt gaaaatatga ttggcggttc agcatttcta gaaaaagaag
    12601 tgtataaata tcttccggaa acatcattta ctgacaaata tatcggcttt ccaaatgcag
    12661 cagtcgatcg aatcgtccca ttacaacacc atgaagatcc tttattcgtc caagtggaac
    12721 ctttcaaaga atgggtcatt gacgatagcc aaagaaaaaa taaaaaaatc caattaaaag
    12781 gggttttata tgtagatgat ctagaaccat atatcgaacg caaactattt agtgtcaata
    12841 ctggtcatgc gactgtcgct tatacaggtg ccttgttagg ttaccagacc attgatgaag
    12901 caatgcaaga tgcgttagtt gtggcacaat taaaatcagt tttgcaggaa acaggaagtt
    12961 tgctgattgc caaatggggg tttgatgcag agcagcatca tgcgtatatt gaaaaaatca
    13021 ttcatcgctt ccaaaacaaa aatatctctg atgcgatcac acgtgtcgct cggacaccat
    13081 tacgtaagtt aggttatcaa gaaagattta cacgtccagt gagagaacta caagaacata
    13141 acttgacttg cccacatttg acggcaacaa tggggattat ttttaattac tatgatcctg
    13201 aagatgaaca aagccgtcaa ttgcatgaaa tgaagatcca tgaaaacttg gaacaattga
    13261 ttcaagaagt cacaggaatc aatgatccga aaacaatcgg gaatatcaag caaaacgtga
    13321 accgttatgc caagcaagtc gcttaaaata ggatacgaaa aaggggaatg tgacgaaatt
    13381 tttgtcacat tccccttttt cgaataacta ggctgtttgt ccttcaagat agggcagatc
    13441 caattcttta ccgtaacgtt gttctaaagc taggcggatc aaacgagctg ccaggttctc
    13501 atttcttgca aggataggtc catggaaata agaaccgaag acatttcggt aaatgacacc
    13561 ttcagattgg tcttcaccat tatttccttg accttgtacc actttcccca aaggtcgttc
    13621 accttcacct aagaaagtcc gaccattgtg gttttcaaat ccataataag tttcattgaa
    13681 ttcttcgtta tggataacga tatcaccgat aaaccggtta ttttcctgac ttaacgtgta
    13741 gtgatccagt gcactgattc cttggatctt ttctccatta gctcccatgt agtagtgacc
    13801 tagcaattgg tagccaccac aaatggctaa catgacgcca tcattttcga tatagttgat
    13861 caaagaatct ttctttttct ggatgtcttt tgaaatgatt aattgctcaa agtcttgacc
    13921 accgccaaag aaaaccaagt catatttatc agcatcaaaa ggttcatgta tactaacgat
    13981 ctccgtatgg caagaaaccc ccattttttc tgctatatat ttcaacatca aaaggtttcc
    14041 gttatcacca tatgtgttca tcaaatttcc ataaaggtgg gcgatattga gttcataatt
    14101 agccacggtt cattcctcct ttgataaatc cttgagcagc tagttcttta cgaagctgca
    14161 atacagcagt gtaagtagct aaaatataga catgctcagt tggcaattct ttgatttttt
    14221 cgattacttc tggtaattct tttgtttctg tcaatttatt ttctggaatc ccggcaactt
    14281 ttagacgtaa agtcatatct gtatgacggt ctcctccaga aataacagct gggatatcca
    14341 tatcggcaaa gttttcaaaa ttaccatccc aaatccagct gacatcgatt ccgtctgcgt
    14401 aattggcatt taataaagcc actaaagaaa atggataagg agctagacca atcatatcga
    14461 ttacttgatt gatacctaca ggatttttga caagtactaa tgtacatttt ttcccattga
    14521 tattgatgac ttcttgtcgg ccgaatactt tctcgtcata tcctaaacct tgtttgattt
    14581 tatcaggatc gacattgaag tactctgcca ctgcagtagc tgctaaagca ttgtagacat
    14641 tatacatacc gccaacttcg attccgtatt catgaccatc gatcacgaaa tctgctgaca
    14701 cattgtccat ccgtaccata tcagttaatc gataatccaa ttcaggacgt ttgaagtcac
    14761 aatttggaca gtaatatttc cctaagtttg cataagtgat cattttataa tgcaagatgt
    14821 gatgacaatt tggacataag acaccgtctg tattgtaatg agccatttgt tcacgatctt
    14881 cttcatggtc aaagccataa tattttctag gattgactgt ttcgatagaa ttgaagattg
    14941 gtgaatcacc gttactgata atcgttgcat ttggtgactt tgcggcaccg tctacaatca
    15001 ttttataggt cgtatagatt tctccatacc gatccatttg atcacggaaa atatttgtaa
    15061 ataagaacag ttctggtttc atatattctg tgactttgct caaacttgct tcatctattt
    15121 ctaggacagc aaactttttc tgtccttttt ttggttttgc ctgcaagaaa gtcgatacaa
    15181 ttccctgtac catattcgca ccagtagggt tggttagaac ttcatcgaat tgctggcgca
    15241 aaatattgac tgttaaagcg gtagtcaatg ttttaccgtt tgttccggtg acaacgacga
    15301 cttggtagtc ttttgccaaa ctatctagta tatgtggatc gactttcagc gctagtttac
    15361 ctggtaaact tgatccgcct ttaaaaaaag tttttaatgc ccattgcgac gtttttccaa
    15421 ctgcaatcgc aaaatgactg cgtattccca ttatgtaacc tccaaaaacg atttgctgac
    15481 gaataaattc aactaatcat accatatgtt gaaaaaaagg ttaaattgct tttcttattc
    15541 ttaagaaaag gttacggctg aaagtgcatg aaatcggaca aaatcgcatg atttaacaaa
    15601 aaaacagctt gaaacaaaat gattgtttca agctgctgtg attttattat tccctcttac
    15661 ctatattccc attttaaccg ataataattt tctcgcttgg atattcatag cctagatctc
    15721 gtgtttcttt tggcacgaat aacatcaatg tatatagcat tccgatccgc ccaataaaca
    15781 tcagtgtagc aatcgtgatt ttgcccacaa cagacaagtc tccggtaatc cctaaagata
    15841 aaccagttgt tccaaacgca gaagttactt cgatgatgat cgagatcagc gtttgttctt
    15901 ctgtagcaga taaaaaaacg atacaaaaga aacacatacc aagagaaagc ataaagacaa
    15961 cgactgattt tcgcacatca tcttgatcga ttctccgtcc aaaaatattg atgttatctt
    16021 cacttttgag gaaggaatat agatacaaac cgatgattgc tacagtagtt gttcgaatcc
    16081 cgccgcctac agaactagga ctgcatccga taaacatcag taaagaaaaa atgatcagtg
    16141 ttgtgatttg aaaatcaccc aaatcgtgaa tctgcagacc agcattacga gtcgtaatcg
    16201 aataaaacat cgaattgatc catttgacac tcatattgga atcttggaat aaatggtcct
    16261 tttccaatag ataaatcaag acagttcccg aaacaaacaa gataacaaaa gctaacacag
    16321 ctaatttggt aaacaaggaa aaacgaaacg gaagcttcgc attggaacgt ttgtataata
    16381 gccattcccg gcactccatc aatacaggaa aaccaattcc tccgacaaaa atcaaaaaca
    16441 tgatcaggat caagaaaaaa tagtcatgtg caaagggctt gatggaatcc ccagtgacgt
    16501 caaacccaga gttcgtgaca gccgatatcg cctgataaaa accgtaaaaa acggcatcac
    16561 gccaacgatc aaaatagcct ctgtaataaa aataaataga aaagaatgtc ccaaaaagta
    16621 attgaaacca gattaaaata gcaaaagtga tccgaatcag tcggacgata ccagacaaac
    16681 gcggttgatt catatccgtc atgatcagct gtcgctgttt cagtgtgatc cgtcgtttag
    16741 aaaaaatgac aaaagcagta gaaatcatca tgatccccaa accaccaact tgaaataata
    16801 tttccagcag tataataccg ttatcattga acacagaatt gatatcaaaa gtcgatagtc
    16861 cagtcacact cactgtactg attgccatga acagcatgtc cacaaaagaa acatggctat
    16921 ctggttcgcg aaaaatcggc atataaaata gaacgagtga taagaccgtc atcaatatat
    16981 aataaaaaac gatgatttgg atcgatgaga aatgattggc agcaaacttc tgtcctcgcc
    17041 gctgcagcct tcgaaagaat aaatcaacat gcacagtact atcctcctga caatagtcgt
    17101 ttctaccagt atacaagggg aattaggaat actcaaagaa attatcaaac agataacaat
    17161 acagctttcg attaaaatag aaatggctta taataaggaa aatcctagaa aaaagaagga
    17221 ggaggaataa caaattgatt aatgctcaac aaatcgtaga aaaaatgaaa aatcaaaaaa
    17281 taaattatga tacagttctg aaaaaaatga tcatgcaatg ggagaaagaa gaagtaaagc
    17341 ctaagatatt aatacataca tgctgtgctc cttgcagtac gcacacattg gaattcatgt
    17401 ctcaatatgc agagatcacg ttattttttt caaattcgaa tattcatcct aaaagtgagt
    17461 atttgcgaag attacatgaa caaaaacgat ttgtagacca atttaatgag aaaactgacc
    17521 atcatgttgc gctaatcgtt gatgaatacc gtccaaatga attcaccaaa atggttttaa
    17581 caaaccatct tgaaaacgaa aaagaaggtg gtgctcgctg cagtgcatgc ttcaatatgc
    17641 gattagatct tgttgcgcaa aaagcgcaag aactaggata cgattacttt ggaagtgccc
    17701 tgaccatctc gccaaagaaa aatgcagctt tgatcaatca gatcggaatg gatatccaaa
    17761 agatttacgg gacacaatac ttgccaagtg atttcaagaa aaacaaaggc tatgaacgct
    17821 ctttgcaaat gtgcaaagag tatgatattt atcgccaatg ttattgtggt tgcgtgttcg
    17881 ctgccaagca gcaaggatgc gatctgaaag aaatcaatcg ggaagcaaaa gcttacttaa
    17941 aaacatcaac cgtagttttt gaggaaaatt aaagaaatct ttcggaaaaa cgtaagaaaa
    18001 aaataaagaa tttatggtag aaataaggta gactgtataa tttgtccgta gtaaagtaag
    18061 gaaacaagaa taaatttcaa tgaaggaaga gataagatgc gaaaagtagc acctattttg
    18121 aagccaatcg ctgtattaac aatctcgacg attgtcgcga ctactacagg tattgtgaat
    18181 agttccagct accgtgcacc aagttcaagt tctagtactg tagaagaaac aacaccaact
    18241 acttcagtct cgacatctga accaacaaca acggaaagtt tgaatgaaac cactacgaca
    18301 agtacatggg acgatacaac aactagttcg tcgtatgatg agacatatac aactgacagc
    18361 tcaagcgaaa caagtaatac ggtaccagat ggcactccat cggattcaac caatccaagt
    18421 acaagtccgg atacaagtgc tagctccgaa acgataccaa gcagtacgac tgtagatgat
    18481 aacacgcaaa atgatgatgc agcacgtaca gcacagcaaa accaagattc aggaaatacc
    18541 caaacgtata accagcaagc aggtgattct caatgacatt tttactagac cttatcaacg
    18601 gggtgcataa attccttggc tatttagaca tcagtcctaa atatcttaac cgtggatata
    18661 cgattttaag tgtgattccc acgctttatt tattgagaat tgtttatgga ctttggcaaa
    18721 accaaaacta tcttcaattt ttcttatatg gacttgcatt tctagtgctt gtttatttta
    18781 ctgttttaaa tgtattttat tactttttag ataaaaacac gaaagccgat gtcactcagc
    18841 tttttgtgaa gtatttacct gatgaagcgt tcaacatcca gacagaagaa tcgatagata
    18901 atggaaattc gatcgataaa gtgaatacac aagaggtcat ggtttcttat gacgaagatt
    18961 atcaattgaa attagccgag aatatgcggt atttgattgg aaatggtgag atcaaaacaa
    19021 atgaactcgg tcgcatggat ggatttctgg tcgatagaaa tacattgtat ccttattact
    19081 atgtcaagaa aacaggagag aaagagtatg ttctaaatat tggacgaagc tactcggaca
    19141 tggaaaaagt agggaccatt cgacttgact caacagaaga cacattggaa cctgtcggat
    19201 tgttcatcgt cggcggtgat tttgtcaaag acgggttacg ctatcatgag ccttatcgtc
    19261 tgaaattgat tgcaaaaaag gcacagtcgc aggaagaacc agtggtttat agtcgtagcc
    19321 aaagaagaag acattcataa tgtgatgaaa cgccgtgtat cagtggttgc gataaaaacg
    19381 tttattcgga ataaggggga tgtgacacgt cttttgtcac gttccttttt tatataacga
    19441 gaaagataag acgaacacat cacttattct ttcctttcat ttataaacat tgtagaataa
    19501 agaaagtaca acgaagtatt gtgaaaaaac gtaataaata acgaggaaaa tacaagtagg
    19561 aggtaagctg tgaaagaatt tttgaaaaat tgggggattt tgatccttgt attagcggct
    19621 attttattag ctagagtgta cgtgtttaca ccagttactg taaacgggca ttcgatggac
    19681 cctacattaa gtgatggaca acgattgatt tcatctaaga tctcaaacta tgaacgaatg
    19741 gatattatta ctacaaagga accgggggat gaagaacgga tgattgttaa acggatcatc
    19801 ggtatgcctg gagatacagt caagatggaa aatgaccagt tgaccattaa tggcaaaaag
    19861 tatgatgaac cttatctgga tgagttcaaa aaagaatttt cagaagataa gttacaagga
    19921 gaatatgctt atagctcagg attccaagca caagcagaaa gttcatccac ctttacgagt
    19981 gactttgaat atactgtgcc aaaaggaaag tatcttgttc taggcgataa ccgcttgatt
    20041 tcaaaagaca gccgaatgtt tgggttagtc gacaaagata tgatccaagg aaaagttgtt
    20101 ttccgttatt ggcctctttc agaaattaaa atcatgtgat gaaaaaataa aaagaagctg
    20161 tgacatgttt tttgtcacag cttctttttc cgaaaattcc ttcttatttc ttggagttgc
    20221 tcactttttt tgcaatctca ttttaagctt tttggctgat ggataagaaa agcgaagcgt
    20281 ttttgttcat aaatagcttt tccccacgat ggaaggtatg actagtagca gagacaaagc
    20341 ccgttttttc caatcgatta ttcaattctt cttggctaaa gccattatgg actttcggat
    20401 gactaatttg ttcattcttg tcaaagtcta cgatgatcaa ttgaccgcca ggagctaaaa
    20461 tttcataaag ttttgtaaga atattctccg tatcaggaat gtgtaaaagt acaagtgata
    20521 gaaggatgag attagcttgg acagcaggaa attcgacaga agcatcagcg tggatcgttc
    20581 ggacattttt cagatctgct gcttggatct tttcttctgc cattttcagc atagtttctg
    20641 aagcatcggc aatgatcagt tctttgaatc tttccgcaag cggtaaacta acaagcccag
    20701 ttccgcctcc gtaatccagc aggacttttt ggtggctgtc gcgcggtaga taagtagtta
    20761 gttcttcgcg aataatcttg gctaatgctt gacggtcagg ggaatcataa tggttagcga
    20821 tggaatcaaa aatatttttt gtcatcaaat agctccttac gtaaaacttt gaaattttaa
    20881 cttattatag cacgtgaaaa gaaagaaagc atgctatact caattcaaaa agggagaatc
    20941 tagaaagaat atgccgatat cgtttgtaaa agatagagag gaaaaaggaa agtgtgtccg
    21001 agaaatatta ctagacttgc ctgagtggtt tgggcttcct gaatcaacgg aaaaatatat
    21061 cgaggaatca agtaaactac ctttatggtg tgaaaaaaga aaagaagaat atttaggctt
    21121 tatcactctt tcacagacaa gtgaagatac tgccgaaatc tattctattg tatgggaata
    21181 aaaaaagact atcatcacca aggattagga acaaaacttt ttaaagaagc agaaggttac
    21241 gcagcaaaac attacaaata tttgcaagtg aagactgtag acgaggggca ctactctata
    21301 tatgatcaaa ctatttgttt ctacgaatca ttaggatttt caaggttgga agtttttcca
    21361 aatttatggg atgaatggaa cccatgttta gttcttgtca aaaaattgga acaaaagtga
    21421 gcaatagatt taatactaat ctgtgcttga tgaaaattct cactgtaaaa aatgctgaaa
    21481 atcaagtata ataccatagg aacaaactgg aaggtgaaaa agagcatggc acaactattt
    21541 tttaagtatg gcgcaatgaa tagcggcaag acgatcgaga tcctaaaagt cgcacataat
    21601 tatgaagaac aaaataagcc agttgtctta atgacaagcg gtattgatac aagagatggt
    21661 ttaggcgttg tttcaagccg aatcggactg aaacgtaatg cgatgccgat atttgaagaa
    21721 acagacgtat ttgacgtaat tcagaaaatg gaaagcaaac cctattgtgt gctgatcgat
    21781 gaagcgcaat tcttaaaaaa gaaacatgtc attgctttta cgagaattgt ggacgaattg
    21841 gatattccgg ttatggcatt tggtttgaaa aatgattttc gaaacgagtt atttgaagga
    21901 tcaaaatatt tattgcttta tgcagacaaa atcgaagaaa tgaaaacaat ctgttggttc
    21961 tgccacaaaa aagcaatcat gaatttacat tatattgatg gaaaccctgt ttatgaaggc
    22021 gatcaagtgc aaattggcgg aaatgaagct tattaccccg tttgtcgaaa acattacttt
    22081 cacccatcaa tgattacaga aggagaataa gcatgtacga tcaattacaa gcaattgaag
    22141 accgttatga agagcttgga gaacttttaa gtgacccaga agtgatttct gatacaaagc
    22201 gttttatgca gctttcaaaa gaagaagcaa acacgcgcga aacagtcgaa gtttatcgtc
    22261 gttataaaga agtagtacaa ggaatcaccg atacagaaga actgcttggt gaaaaactgg
    22321 atgatgaaat ggctgaacta gcaaaagaag aattatctga attaaaaaaa gaaaaagaag
    22381 tcttagaaga aaaaatcaag atcttgcttt taccaaaaga tccaaatgac gataaaaata
    22441 tcatcatgga aatccgtgga gcagcaggcg gagacgaagc agcattattc gctggcgatc
    22501 ttttcaatat gtaccaaaag tatgctgaag cacaaggctg gaaaacagaa gtgatggaag
    22561 ctaacgttac cggaatcggt ggatataaag aagtgatcat gatgatcacc ggagacaacg
    22621 tatattcgaa attaaaatat gaaagtggtg cgcaccgcgt ccagcgtgtt ccttcaactg
    22681 aatcgcaagg gcgtatccat acttccaccg caacagttgt cgtgatgcca gaagctgaag
    22741 aagtagagat cgatattgaa gacaaagata tccgtacaga tatctatcat gcttcaggtg
    22801 ctggcggaca gcacgtcaat aaaacagcat ctgctgtacg tttgactcac ttaccaacag
    22861 ggatcgttgt tgctatgcaa gatgaacgtt ctcaaatcaa gaaccgtgaa aaagcaatga
    22921 aaatcttgcg tgctcgtgtg tacgataaga tccagcaaga agcacaaagc gagtatgatg
    22981 ccaatcgaaa atcagcagtc ggaactgggg atcgttcaga acggatccgg acgtataatt
    23041 tcccgcaaaa tcgtgtgact gatcatcgta tcggattaac tatccaaaaa ttagatcaga
    23101 ttttagcagg gaaattagat gagatcgttg atgcattgat catgtatgat caaacatcaa
    23161 aactggaagc tatgcaaaat gggtaaaatg acctatcgag aagtcctgtc acgggcttct
    23221 tcttttttag aggatcatgg gaaagaagca tatagtatcc aatttttatt tttggaacga
    23281 aaacaatgga aaaaacttga ttggctcctt catatgaacg aagagatttc agaagaagaa
    23341 cagcggttga tcgaaaccga tctgcgactt ctgcttgcag atcatccacc tcagtatttg
    23401 ctaggatatg cagattttta tgatcatcgg ttaaaggtaa ctgaagcaac actgatccct
    23461 cgaccagaaa cagaggagtt agtcgaatgg tgtttagacg agacgcctgg tgtaccgtta
    23521 gaagtgatag atattgggac agggactgga gcaattgcta ttagtttgaa agcagcaaga
    23581 aaaaattggc atatatctgc tgtggatctt tcagaagaag cattagaagt agcgaaagaa
    23641 aatgctcaga aagaaggaac gaaaatcagt ttttatcatg gagatacatt aggaccagta
    23701 atggatcagc aatttgatgt gattatttct aatccgccgt acatcagtcg gaatgaatgg
    23761 gaactgatgg atgaaagtgt ccggtcattc gaacctaaaa tggccctttt tgctgagaac
    23821 gatggattag ctatttatga aaaaatagca gttgaagcac caagcgtact aaaatcaaat
    23881 ggaaagattt ttttagaaat cggatttcgc caaggtgaag cagtaaaaaa aatatttcag
    23941 caagcatttc cagataaaaa agtggcgata aaaaaggatc tttttggcaa tgaacgaatg
    24001 atccaagttt atggttgaag ttgtggatga aaaatttttt atttgttttt ttattataaa
    24061 aaaacactta tttgacaagg atgtaaacga ctttttggtt tatcaacaag tttatccact
    24121 attgacaaat agattatcca caaacagtgg aaaacttgag gataaactca gacaaaataa
    24181 gaatgtatga aaaaggggtt gtggataaac tgtggaaacg aaacgatatg atgaaacaga
    24241 attgcaagag gcagccgaag cactgaaaga aggagaactt gttgcttttc ctaccgaaac
    24301 agtatacgga ttgggcgcca acgctctttt accaaacgct gtcaagaaag tgttttctgt
    24361 aaaagggaga ccgcaagata atccattaat cgtccatgtc gcctcttttg aacaagtaaa
    24421 agagtatgtg gacaactttc atccggcagc agagaagatt gtgaagaact tctggcctgg
    24481 accattaact ttgatattta agatcaaaaa agacactttg ccctcagttg tgacgggagg
    24541 attatccaca gctgcatttc gtataccgga taacaaaaaa acactagaag taatcgaact
    24601 ttccggtgtt ccgcttgtcg gtccaagtgc aaatacgtcg ggaaaaccaa gtccaacgac
    24661 tgcagatcat gtatatcatg atctacaagg aaaaattacc gggattattg atgatggagc
    24721 tacgcgaatt ggtgtagaat ccactgttct tgatttaagt gatccaacag ccatgcctat
    24781 gattttacga ccaggtgcag taacgaaaga acaaatcgaa gcagtcatcg aatctcctgt
    24841 tgctattgat cagcatcttg taaaagaaaa tgaaacacca aaagcccctg ggatgaaata
    24901 caaacactac tcacccgata cacgtgttct gatggtcaga gatggcgatt ggtcaactgc
    24961 agttcaatgg gcaaaaaata agaagatccg tgcaggtgtc atagcaagcc ccgaaattgc
    25021 ggatcaagtg cggacagata ctgcagctgt ttatatgtat aacgacaact cagtagaagc
    25081 ggcggctaaa ggattgtttg caggtctaag aggattagat gaaccaacac ttggattaga
    25141 tttgattttt gtacaagtgt atccagaaac tggattgggg aatgcttaca tgaatcgctt
    25201 gaaaaaagca gcaggacaaa attattttga aaaatgatca attggttatt gtcgcattct
    25261 tttagtatga tacaatgcta tcaagtaaat cttctatcag tgaacgaaaa actaagcgta
    25321 actaatcgta atagaagaga tacgaatatt tggcaatttg tttttgatgg gaaaaataaa
    25381 attgtaggaa aataaaattg taggaaaata aaaaggagct gttgtttgtg gtagattaca
    25441 aaacgtttga ccctgatctt tgggctgcga tcgccaaaga agaagaaaga caagaacata
    25501 atttggagct gattgcctct gaaaactttg tctccgaagc agtgatggct gcacaaggaa
    25561 gtatcttgac aaataaatac gcagaaggtt atccagggca tcgctattat ggtgggtgtg
    25621 aatttgtcga tatcgttgaa aatttagcga ttgaccgtgc aaaagaatta ttcggagcga
    25681 aatttgcgaa cgtccagcct cactccggct ctcaagccaa cacggctgct tatctcgctt
    25741 tggtagaacc aggggacacg atcttaggaa tggatctttc cgcaggcgga catctaacac
    25801 atggatcacc agtcaacttc agtggcaaaa cctatcactt tgttgcttac ggtgttgatc
    25861 cgacaacaga agttattgat tataatgtgg tacgtatttt agctagaaaa catcaaccaa
    25921 aattgatcgt agcaggtgcc agtgcttacg gacgaacgat cgactttgcg aaattcagag
    25981 aaatcgcaga tgaagtaggc gcaaaactga tggtagatat ggcacatatc gcaggattag
    26041 tagcagcagg acttcatcct aatccagttc cttatgcaga tatcacaacg actaccactc
    26101 ataaaacatt gcgtggccct cgaggcggca tgattttgac aaacgatgaa gcattagcaa
    26161 aaaaaataaa tagtgcggta tttcctggta ttcaaggcgg ccctctagag catgtgattg
    26221 cgggtaaagc agtagcattc aaagaagcat tagatcctgc atttaaagaa tatagtgaac
    26281 aaatcatcgc caatgcaaaa gcaatggtca aagttttcaa tcaagcaatt ggaaccagag
    26341 tcatttcagg ggcgacagat aatcatctga tgttgatcga tgttcgcgag ttaggtataa
    26401 atggaaaaga agcagagagc attttggaca gtgtgaatat cactgtaaat aaaaactcga
    26461 ttccttttga aacactaagt ccattcaaaa caagcggtat tcgaatcggc acgccagcaa
    26521 tcactactcg cgggttcaaa gaagaagatg ctgtaaaagt ggctgaacta gttgtcaaag
    26581 cattacaagc aaaagatgat aacgctcaac tagacgaagt caaaacaggt gtacgcgaat
    26641 taactgaaaa atttccgttg cataaaaaat aaaaatttaa attccattag taaacagaaa
    26701 agttcaatgt tgggcttttc tgtttatttt ttgggaaaac ggattctttg acaatatcgg
    26761 tgatgctctc tagtatatga ggtgtaattt tagtcttcac actaaatctc agggaggaaa
    26821 agtcatgact gatcgtatct cgttagaaaa ggaagcagta gcattcagtg atgcaaatgc
    26881 gcctcatccg cgtatctatg aactagcacc ggaagaagga agagttttac tagaagaagt
    26941 acaagaatca cctgtgaaca aatattccgt cgatattgaa gacttgatgg tggatactgg
    27001 cgaatgggga aaactcaata ttcgtctcgt acgaccagaa gggaatatgg ataaattacc
    27061 agttattttt tatattcatg gagcaggctg ggtttttggc agtgctcaaa cccatgataa
    27121 attgatcaga gaacttgcgg ttcgtacgaa ttccgtcgtt gtctttccag aatatagtcg
    27181 atcaccagaa gcaaaatatc caacagcaat tgaacaaaat tatgctgtgt tgcaacagct
    27241 gaataaatta gccaagtcaa aaaatctgga tctcgagaat ctaatcgttg caggagattc
    27301 agtaggtggt aacatggcta cagtcatgac gatcttaaca aaagaacgaa agggcctccc
    27361 aatatccaag caattgctgt attatccagt cacaaacgct gattttgata cagattccta
    27421 tcatgaattc ggagaaaact attttttgac aagagaagga atgatgtggt tttgggacca
    27481 atatacgacg aatgaagaag agcgtgctga aatcacagct tcgcctttga gagcaaatat
    27541 aaatgaacta aatgatcttc cttcagcaat gattttaacg ggagaagcgg atgtattaag
    27601 agatgaaggt gaggcttatg cgcgcaaact tcgtgatgca ggggttcctg ttacacaagt
    27661 acgcttccaa ggaatcatcc atgattttgt catggtaaat gctatggatc agacaaaggc
    27721 aacgcgtgca gcaatggcat tatctacttc ttggatcaag aaaaaagaat aagctttgct
    27781 tgtccgcagg aaaacttctt ttcaaaaacg gattttctta ggaaaaatgg cgagtttgac
    27841 tagtcaatca cttgattttg ttttacaatt aaaaagaaac gacagaacaa aggagagctt
    27901 aaaaaatggg caaatttcaa gtgatcgatc atccattgat tcaacacaaa ctaactatta
    27961 ttcgggacaa aaactgcgga acaaaggttt ttcgtgaagt agtcgatgaa atcgctatgt
    28021 tgatggcata tgaagtatca cgggatatgc cattggaaga catcgtgatc gaaacaccga
    28081 tcactgaaac aacacaaaaa acgttgtctg gtaaaaaagt agcgattatt ccaatcttgc
    28141 gcgcaggtat tggaatggtt gacggtatct tggaattgat tccagctgct aaagtgggac
    28201 atatcggtct ttatcgagat gaagaaacat tggaaccaca tgaatatttc gtcaaacttc
    28261 cagaagacat tgatgcacgt cagttgtttg tagtagatcc aatgttggca acaggcggat
    28321 cagcaatcat ggcaatcgat gcattgaaag aacgtggcgc gtcgaacatt aaatttgttt
    28381 gtttggtagc agcacctgag ggagtaaaag ctttgcaaga agcgcatcct gatattgaca
    28441 tctatacagc ttctctagat gaaaaattga atgaacatgg ttatatcgtt cctggactag
    28501 gggatgcggg tgaccgtttg tttggtacaa aataagtaaa tacgaaaaag ggtgtgacac
    28561 aacttttgtc acatcctttt ttggtcattt ttaacgtttg atgcagaaca gctttttcac
    28621 agctttcgtt tgcatataaa aaaaccatcc caaaaatgca gagatggtca aattcaaatc
    28681 ttttttagtt ctttgtagtt aacgattact acacccttac tttgcgtcat caagttcgca
    28741 ttttctgcag tttcatcaat ctcaacaaca gcggaatttt tcaattgctt tgaaatcgtt
    28801 ccagtttgcg acttgccgtg aattgtgaac attacgtgag tattgatctt gaatttttca
    28861 ccaatttccg atggtacgat agttgtatca aattttccaa aagttgccat tttcataaaa
    28921 cctgcctttc acatcaatta taccacgttt tatgaaaaat atcatgaaat taaactaatt
    28981 ttccatcgga ctctttacaa tcagccaaat agagtatata atttcttttg gataaggcca
    29041 gcttagctca gttggtagag caacgcactc gtaacgcgta ggtcgtaggt tcgatcccta
    29101 tagctggcat taaaagagaa gacagatata tcaaggattt ttaatccatt gatacatctg
    29161 tctttttgtt taaaggaaat aaagtatgct ttcttagcaa tagagcatgt attatttcta
    29221 taaaaattta ggagaataaa acgactagca atatagctgt gaaatcaaat atcacatgaa
    29281 ctgcccaact tgtaatgatc gagttgcttt taatggcagc ttggttgaat aacaatcttg
    29341 ccaccccttg tatcaaaagg atgtgtgcta cagtgtgtaa aatatttcca ttatcataag
    29401 tactgtaatg gataaatcca aagatgattg ctgacaagaa actagcgaca ggaatgctga
    29461 acttactaga aaaaatagcg agaaaataca ctgagaacaa ttcttctcca agtatcatga
    29521 taggcaaaat aataaataat aacgggctga aagcctcatt tattggattg cctgttaaac
    29581 cccatttcaa aatttgttgc aaaaataccg agactgcggc actgattact acattgataa
    29641 aaaaatattt ggctatattt ttgacaggag cgacaggttt cgagaacatt tttttcgtat
    29701 cttttttacc aaaaacaagt gtaaatgcta taaatccagt gatagttaaa gaaaaaatgc
    29761 taataatgga tggcgcaaat agcaacccta acaaaccgag tacaacgaca atagtgccca
    29821 atatcccttt tttaagttct attttttttc ctaaaatgtt attcatgata ataactccta
    29881 ctattcagtt tttgaagata gagtcagtat acatgaagag ttaaaatagg caatgttttt
    29941 ttatggatat ttgtattgct aaaaatttat cttatatatt cattttgatt atactacttt
    30001 tatttgtaaa aattttctag caaaaccaag tgcttgcaac tgattaagcg tacaattttt
    30061 tagatgttcc gagcgtactt caatcatttc aaaggagttg ctacttaaat cgatattttt
    30121 taaatcagta tcaaaaaagc tagcattttc taaatcatta gtagaaaaca ttattttagt
    30181 gagggaacag tctacaaaat ctgcgcttga taagacagag tgctcaaagg tactttcttt
    30241 tatgtttgaa ccagataaat ttacatagtc cattttacaa ttctcgaata acgtgttccc
    30301 aatataactt tccatcaatt tagtacctgt taatttacaa ttgacaaatt tcacgcgatg
    30361 caacatgctt tttgtcaata tacagcctga aaaatcacag ttttcgaata tacagtcggt
    30421 aatctccatt ctttgaaaat cattggaagc aaaaaatgca tacttgaaaa tagatttgta
    30481 aataattgga tggcagatta tttggttttc gatgacctct ttttgtgaaa ggatattata
    30541 cagttcaaaa tcttcgtttt catagatatg aaaaaaggat cctttattca agcttgcttc
    30601 attaacttta ggaaaaatca tatttaatta cctccatttt cataaagtca tattaacaaa
    30661 agctaaacca acttacatta gcagaaaatg agataggttt tcgccttttt cgataacgat
    30721 agtgtcgcta tctcttgaaa cgttcttaga attgccctga gagacacaaa ttaggcgtaa
    30781 ttctaataaa aatcttagaa taaaaatttt tactgattta atttagaatg tttttaaaat
    30841 aaaaatcgtt gccataacag tgtattgaaa ggttttaaca atccagtaat gatttaaaaa
    30901 aatctagatg tagcgtatac tttgtttata gaatgtagtg ggaagaaata tatttttggg
    30961 aggaaatcgt gatgtctaaa agtgaagaaa tagaaaacat ggtactaaaa ttatatgatc
    31021 tcgttttaaa tccagagatc aaagaaaagg aacgtatact tttgatagac gcaaagacag
    31081 gcttagaaaa aggtcagtat tatcctaaag tcataaataa tttggaacgt agtttacgtc
    31141 cgttagcaat caggggagaa ttgtctaaac cagtatcacc gttttatatg gagatatcaa
    31201 caataggaaa atttgaaaaa gaattaggtc gaggaatggc ttcggcaccg attacttttg
    31261 ggcatttata aaaacgagtt attcatctca atgaattaaa aagtatagtc aatctcataa
    31321 tgcaggctag gttcatttat ttgaacagag tctgtatttt tttattctaa ataaagaaac
    31381 agatgtttct ttatattgta ttttatcctt taattaacac aaaaacagct agtataaact
    31441 aataatgtta attaaaagtg tattttatga aactatcgtt atttattaat gttgcatttt
    31501 tgtaagttaa aaattggaaa tatagattga aaaaatgaaa gcaataagta aaataaaatg
    31561 aatatatgcg aaaaaataat ttacattagg aaaaaccttg taaaaacagt tttttggcat
    31621 atttattttt tataaatatt tgtaaaataa ctatcaattt tttagttaaa agattggaaa
    31681 tgagtggggg aggaattgaa gaaaggattt ttgagagatg atatagtagg ttttattttt
    31741 agttaaaata ggggagatag aaaaaatgaa aaagtgtaga aatattattt tatcaatgtt
    31801 atttattatt actaatataa catcactgat tcctgttcat gtctatgcgg atgcaggcag
    31861 agatatcagc agtaatgtca cttcgttgac cgtggaccca acgaatatta cagatggagg
    31921 aaacataaaa gtaaaattct cgtttgacga aaaaaaacaa aatatccaac caggtgatta
    31981 tctttggatc aattggccaa gtgaaggaaa tattcgcggt gaaggattcc aaaaagaaat
    32041 cccattaatg attgaaaata aaaatgttgg aactttaacg gtcagaaaag attctgcgca
    32101 ggttgtgttt aatgaaaata ttaaaaacct agactcagta gaaggttggg ggcaatttga
    32161 gatacaggcc agaaacgtaa ccgataccgg tgaagaaaat acgggaccat tcaccgtgac
    32221 gagcggtgat aaaacagcta ctgtaaatgt gacaaagcca gcttctggtt cttcttctag
    32281 cgttttttat tataaaacag gagacatgct acctgaagat actaagcaca ttcgatggtt
    32341 tttgaatatt aacaataacg gcacttatgt tgaacaacca gttaaaatca gtgatgaaat
    32401 ccaaagtgga caaagattag atccaagtac gtttgaaatt aatcaaatac acttaggtga
    32461 acagaaggtt tatagaggag aagagggaat ccaacaattt ttacaagatt tccccagcgc
    32521 tacatttaat ttttcagtaa ctgataatta cattgaaata actataccaa aaaactttgt
    32581 caatcttagg aaaataatgg tgagttataa gacgatcata gaaaacccag aacaaataaa
    32641 ttttgagaat cattcggaag cttggtttaa agaatttaat aaacctgctg ttgatggaga
    32701 aagtttcaat catacagtta aaaatatttc agcttctggt ggagtcaacg gtacagttag
    32761 aggcgaattg aagattttca aatatatcaa tgacacagag attggtatcc caaatgtgac
    32821 tttcgaatta agacgagcag atgaacagcc tattcaagga cagtctagta tcctgttgac
    32881 ttcgaatgaa cagggagaag ctagtatcaa aggcctgcaa gtaggagact atgttgtaaa
    32941 agaaaaagaa gcacccaatt ggattgattt tgatccacta agttcaaatg aactcaaatt
    33001 ctccataaac gaaaatgata cagagggagt cagtttacct atttataaca agaaaaaggt
    33061 tacgaacatc acagcaacta aaatttggaa cggtggaacc actccaagac cgagtattta
    33121 ttttaaatta ttcagagcaa gtacaaacaa ttgggaacca gttcctgatg cagaaacaaa
    33181 acgattagac aatggaataa cttcagtgac ttgggaagat atccaacagt atgatgatag
    33241 tggaaacgaa tatacgttta aagtgcaaga agtagatcaa aacggaaatg attatgtccc
    33301 ttcaggttat caaaaaattg aaaacgggct agtcgttaca aatgagaata aagaagtcat
    33361 ttcagtctca ggacaaaaaa catgggaaga caatgagaac caagacggca aacgaccgac
    33421 gacgatcaca gtaaatctat tagccgacgg tcaaccgatc caacacaaag aagtaagtga
    33481 aaaagatgat tggcgctatc gtttcacaaa tctgccaaaa tacagagacg ggcaagaaat
    33541 catctatact gtaacggaag acaacgtgcc cgaatacagt acgacgattg acgggtataa
    33601 catcaaaaac agttatacac cggaaaaaac aaatatatct ataccaggta gccatataac
    33661 accgtggaaa aattttccag agaagacaga gagagagaaa attagaaatc tattctctca
    33721 aaaattgcaa atatttgctc atacaggaga atccagcgaa caaagaagca attatattag
    33781 taagagagct gtacctaaac agataacaaa taaatcaaaa agcattcttc ctaaaacaag
    33841 tagtaaaaaa tctagttttg ctgtaatcat tggtttattg atagtaacta tctgtgctgg
    33901 gatattctta caaaaatata aaaaagttta gttagaatat aatatttttt gttaaatatg
    33961 actgaaatca aaagaataaa attccgattt ataatcgaaa aaagaagcat ttttatatat
    34021 gcttcttttt tcgtagaatc aataaatatg gatttggcta actatggaag aatactcgta
    34081 ttagttttca gcgttcatac tagttgttac attgtttgat tggccaaaag aatttctgat
    34141 atattttgtg ctaaataaag aaaaagacgc ttgaattggg aaataagaaa actactctat
    34201 cattacaaat tttcataaac tggcagatgt tctaagtaaa caagtatctt ttcaaagtcg
    34261 gaaaaatcca taatcaacgt agtggtattg atatttggat gaaagcctac ggtatcttga
    34321 cgatcaatag cagcatcgat cacgacttgg atttttttct ctttgtcgtg catcaatgct
    34381 aatggagtca ctgtacctgc tggaacgcct aggaggtcag gaagctgttc ttcagaaaca
    34441 aaagataagc gcttttcttt taattgttca gctagttgtt ttaaatcggc gtgcttttca
    34501 tcaggcaaga tgacaagata gatttgtttt ccttttcttg atttcaataa tagatttttt
    34561 acttgcggac caggtaggga aaaagggaca tttttgactg acgtaatcgc aggatgatcg
    34621 actttttgaa aagagatacc cagttttttt agtagttcat aagcttcttg ttcggttgca
    34681 cgactcatcg cgcatcaccc tccttttttt attagtgtat cataaaaaag agttgacaaa
    34741 tgaaaaataa tcatgtaaat tacacgtaaa gttaaaacaa atgacatcga aaagaagagt
    34801 agccgttagg tgtttttaga gagtctctgg ttggtggaaa gaggcagcag ttaaccgtga
    34861 aacacatctt ggagtcgatt ttctgaagcg tatagtagga aaatccgggg agcccgttac
    34921 agctgcggtc gttgctagat gaccagataa ggctggcttt tccgtgagga gtcggtaaaa
    34981 aaaggtggaa ccacgtgatt aacgtccttt gatcttcgga tcaaaggact ttttgttttc
    35041 atctgaacgg caacgactgt gtgaggtttt ttctgcaagg aaaaaataaa cagaggtgga
    35101 accacgtata atacgtcctc ttggcatttg ccaagaggat ttttttattt taaaggagga
    35161 aaagaagatg gagtatttga ttgaagttat gccgcaatta ttagtaggag cactcacaac
    35221 attgaaatta tttttattta ccttgattgg ctcattacca ttagggattg ttttagcatt
    35281 aggattgtct ttgcatttta agccgctacg ctacttgctt caaacatatg tatgggttat
    35341 gcggggaaca ccgctgttgt tgcaactgat ttttattttt tatgggttgc cgacgattgg
    35401 gatcgttttt gatcgtttcg aagcagcact cattgccttt atcttaaact atgcagctta
    35461 ttttgcagag atctttcgtg gagggataca atcgattcct caaggtcaat atgaagcagc
    35521 gcaagttttg caattaagtc cctttcaaac ggtgacgaaa atcgtcatcc cacaagtgac
    35581 aaagattgtt ttaccttctg tagggaatga agttatcaac ttggtcaaag attcttcctt
    35641 gatctatata ttaggtttag gtgacgtaat gcgtgctggg aaaatcgcga tggaacgcga
    35701 cgcgacttta ctgcctttgc taggcgtggc aatcatctat cttacattga ctggtattct
    35761 aacaatcgta atgaaacaag ttgaaggaaa attaaattat taccgctaac tgataggagg
    35821 aagaaatatg attgaattga agaaagtgaa caaagcattt ggtgaaaaaa aaataatcaa
    35881 agatttgaat ctaatcattc cagatgggaa aacattagct atcgtaggtc cttccggtgg
    35941 cggtaaaacc acgcttttac gtatcttggc tggcttagaa agttctgaca gcggagaatt
    36001 ttatttagac ggtgtaccgt tcaacccatt cgagcttaaa atgaaagaac aagttgtagg
    36061 agtcgtattc caagacttcc agctatttcc acatctgaat atttttgaaa acattacctt
    36121 agcaccaaaa atggtattga aacagacaaa agaagaatac accaaaaaag cagaagaatt
    36181 agcggcttca ttagggatta gtgatttatt gaatatctat ccttatcagc tttctggcgg
    36241 acaaaaacag cgggtagcga ttgccagagc attggctatg aatccacggg tattggctta
    36301 tgatgaacca acaagtgctt tagatcctga attacgccag caagtcgagc gtttgatcct
    36361 atcattgaaa gaagatgggg taacccaaat tattgtcacc catgatttag tatttgcaga
    36421 aaatgtcggt gatcaattac taaaagtttc cccaattcat taagaaagga gaagatagag
    36481 atgaaaaaaa ccagttttct attcgctttg atcgcaggtc ttcttctttt tgcaggctgt
    36541 tcgaacaaaa aaacttcagc agataattgg gcgactatca acgaagagaa aaaaatcgtt
    36601 ataggtttag acgatacatt tgttcctatg ggatttagag ataaagacgg gaagctcaca
    36661 ggatttgata ttgatttagc caaagcagtc tttgaacaat atgggattac ggtagacttt
    36721 cagcccattg actggtcaat gaaggaattt gaactgaaca atggaacgat cgatttgata
    36781 tggaacggct attccaaaac gccggcaaga gaaaagaaag tgcaatttac aaaaccttat
    36841 atggaaaacg atcaagtgct gatcacacct aaagaatcag gaatcacaaa ctttggacaa
    36901 atgaataata agagattagg tgcgcaaaat gggtcatctg gttatgatgt atttacgaaa
    36961 caaccagaag tattaaaaga gatagtcaaa aaccaagatg ctgttttgta tgatagtttt
    37021 aatgaagcat tgatcgatct gaaaagcaga cgggtcgatg gtctgctgat ggataaagta
    37081 tacgcagact attatttgaa acaaagaaac gaactagaag acttcaacat aacaaaaggt
    37141 tcttatgaga gtgaggattt tgcagttggt gcacgcaagt cagatagtac attagtgaaa
    37201 aaaatcaatg aagccctaga tcaactagag aaaacaggtg aattccaaaa aatatccgat
    37261 aaatggtttg gcgaagatgt tacgccgaga aattaacaaa taggggactg tgacaaaaga
    37321 cgtgtcacag tccctttttc cgaataaaca gtgttctcct gccaactcct tgtgactcgg
    37381 agctgaatgg caggctcaca acctcttggt aaacggtgtt caaaagccag tttttcggta
    37441 ttaagccaaa tttatgcaaa aatgtagaaa gccattttca caaaattttt cttactactc
    37501 gaaactaagc gactttttca caacctcctt tacataattt tattttgttg tggaaggggt
    37561 ttcgtgttat tctaaaagag gaacgattga aggttatagg aaaggaagag atgaatggaa
    37621 cacaaagaac ttacctcatt tccaaaagat tttctgtggg gctctgcttc tgcagcgtat
    37681 caagtagaag gagcttggca agaagatggg aaaggagaat cagtctggga tcgatttgta
    37741 cggatacctg gaaagacatt taaaggaacg aacggtgatt tggcagtaga ccactatcat
    37801 cgttataaag aagatattgc tttaatgaaa gaacaaggtc tgaaagctta ccgcttctct
    37861 gtagcttgga cacggatttt tcctaatgga cgaggagaag tcaatcaagc tgggctcgct
    37921 ttttatgaga gattgatcga cgaattgatt gaaaacgata ttgaacctat gttgacttta
    37981 tatcattggg atcttccaca agcattgcaa gatgaatata atggttggga atcacgtcag
    38041 atcattgaag atttcactca ttatgcagaa acattatttg aggcattccg cgggaaagtc
    38101 cattactgga ttagtttgaa tgaacaaaat atcttcactt cattaggtta tttgttagca
    38161 gcacatccgc caggtgtgac agacccgaaa cgaatgtatg aagttaacca tattgctaat
    38221 ttagcaaatg catctgtcat caataaattt cacgagttag aaatgcctgg aaaaatcgga
    38281 ccaagctttg cgtatacgcc aaattatcca attgacagta atcctgaaaa tgttctggct
    38341 gctgaaaatg cagaagacct gatggccaat tattggatgg atgtctatat gtggggaaaa
    38401 tatccgattg ctgccatgag gttcttagaa gaaaaaggat gggcaccaac gattgaagct
    38461 ggcgatgcag aattgctaga atctgctaaa ccagattttc ttgggatcaa ttactatcaa
    38521 acggcgacga atgcattcaa tccattaaac ggagttggtg ctggaaaaat gaatacgaca
    38581 ggaaaaaaag gttcatcaga agaaactgga gttcctggaa tgtataaaaa agttgagaat
    38641 ccatttgtcg aacgaacaaa ttgggactgg gagattgacc cagaaggatt aaggatcgga
    38701 ctgcgtcgta tcacaagccg ttaccgcatg ccggtactga ttacggaaaa tggcttagga
    38761 gagtatgaca agttgacaga agataaacaa atccatgacg actatcgaat caattactta
    38821 caaagccacg tcaaagccat caaagaagca atttcggatg gagcagaagt cctaggctat
    38881 tgcacctggt cttatacaga tttgcttagc tggctgaacg gttatcaaaa gcgatatgga
    38941 tttgtatatg ttgattaaga cgaaacacaa gaaggatctt tggaacgata taagaaagac
    39001 agttattact ggtaccaaaa actgattgaa gaaaatggag agaaccttta gttcacatac
    39061 ttaaaacaag aaggtacggc tggatatggc cgtgcctttt cttgataaaa tcatttagaa
    39121 attaagaaaa actgtaaaat aagctgaaaa atgaaagaaa gcgtcagttc tttcaaacaa
    39181 aactttagtt cccttacttt tttttgtata atgaaacttg atgaaatgag ggataataaa
    39241 tggcacaaaa gaaacggcct actaaaaaaa ggaaaaagac gaaaaaaacg aaaaagcaaa
    39301 aacagcagca ggaacaaatg ctgacgattg gtgttgggtt tgccttgatt ttatttgctg
    39361 tcttcggctt tttaaaatta ggttttttag gaatattgat tgcaaacggc tttcggatca
    39421 ttgcaggaaa tacttaccaa atcctctgtc ttttattagc cgtattagga ttttggattg
    39481 tcattaagaa tacagagttt tcaattggta aaaaccgacg ctggtttggc ggcatactct
    39541 tttatttcgg tatcttatta ttgttacatg cccatttatt tggcaaactc catactgggg
    39601 aaccaaatat catggggacg acatgggatt tgttagccag tgatataaaa caaagtcaag
    39661 tagacaataa cgttggtggt gggatgattg gagcaatcct ttatcatttt acttacttct
    39721 tgattgcaca gcctggaagt tatttagcag cagtgctatt actggcagga ggagcattcc
    39781 tgttcagtaa tctggaaggc tatcagctgt taaatggtat ccaatcaatt ggagaacgag
    39841 tacaggaatt attggaaggt gatcctgcca agcaagctcg aaagcaagcg gcaaaggaag
    39901 agagaatgaa acagcgcgca gaagcgaaag aagcaaggcg cttagctgca aaagaagctg
    39961 cagaaaaaga agctgcagaa tatgagaaga aaaaagcggt gagccagcaa agggaaaata
    40021 ctgctgatga atggcaggaa ccagaaaata cagagccgga gcagctaagt tttgttccaa
    40081 tcgacagttt tcaagaaaat atccatcctg cgaatctaga gaaaccagta ccagatacac
    40141 caaaacagac caatacagca gaaggttttt cagatgagtt gccagaggat gacggtacct
    40201 cattagaatt tgagattgaa gcagaacagg aaaatcaaga ctatgaatta ccgacagttg
    40261 atttgcttga ttctatacca actgtggatc aaagtgatga gtataaaaaa attgaaaaaa
    40321 atatcggcgt attagaacaa actttccaaa gtttcggtgt cgatgccaag gtcgtcaaag
    40381 ccagcttagg accatccgtc acaaaattcg aagtccagcc ggctgtaggg gtaaaagtaa
    40441 gtaaaattgt gaacttaaca gatgatatcg cgcttgcttt agcggcgaaa gatgtccgga
    40501 tggaagcacc gattccaggt aaatcactga ttggtattga agtaccaaat ggaaagatca
    40561 gtatggtttc ctttagagaa atcatcgaag cacaaccaaa ccacccagat aaattactag
    40621 aagtaccttt aggacgtgat gtttctggac gggtacaaac ggctgatctt tcgaagatgc
    40681 ctcacttact cgtggctggt tcgactggta gtgggaagtc agtagcaatt aatgggatta
    40741 tcacaagtat attaatgcgt gctaagcccc atgaagtaaa actgatgatg atcgatccga
    40801 aaatggttga attgaatatg tacaacggca tacctcatct gttgacgccg gtcgtgacga
    40861 accctagaaa agcagcgcaa gccttacaaa aagtagtaca agaaatggaa gaacgatatg
    40921 aaaaattcgc ggcaaccgga gtaagaaata tttctggtta caatgaattt gttcaacaga
    40981 aaaacttgga aaacggaacg aaacatccaa ccttaccatt catcgtagtg atcgtagatg
    41041 aattagctga tttgatgatg gtagccagca atgaagttga agatgcgatt attcgtttag
    41101 cgcaaatggc tcgggcagcg gggattcata tgatcctagc tactcaacgt ccaagtgtgg
    41161 atgttatcac aggaatcatc aaagcaaatg taccttccag aatggcattt gcggtatcaa
    41221 gcggtacaga ttctcggacg atcattgatt ctaatggggc agaaaagctc ttagggcgag
    41281 gagatatgct attcttgcca atgggtgaga ataaaccgat ccgtgtgcaa ggagcattca
    41341 tttctgacca cgaagtagaa cgggtcgttc aatttgttac agatcagcaa gaagctcatt
    41401 atgaagagaa aatgatgccg acagatgaag ttgaaacgac aggtgctcca gaacagccac
    41461 aagatgagct gtttgaagaa gcaaaagcac ttgtcgttga aatgcaaacg gcaagtattt
    41521 cccttctcca aagaagattt cggatcggtt acaaccgagc agcacgttta gtagatgaac
    41581 tggaagctca tggagttgtt ggcccgtcag aaggaagcaa gcctcggaaa gtattcattg
    41641 agcaggaaga aacatcagaa acgttgccgg acgataatga catgtaaaac ttgtgtgatg
    41701 aagggttgaa aaacgaataa ccaataaaaa gacaaggcat gatgatacca aaagaaaaaa
    41761 tggttttttt ccatcttttc taatacggta tgatgtcttg tctttttagt ttttgtgaga
    41821 ttaaagttct attcgattta tttgtgaagt attgcattaa ggaaatgaat catgtatagt
    41881 atgtagcgaa actttgagaa aaagagggaa aatactttgg aaaaacagtc catttatggc
    41941 ttgacgaatg aagaattaat caattggttt atagaaaacg gcgagaaaaa attccgagct
    42001 gcccaagttt gggaatggtt gtatcaaaaa cgtgtaagta atttcacaga aatgacgaat
    42061 ctatcgaaac aattgatcga aaaattatcg gagcatttta tcatcaatcc tctaaaacag
    42121 atggtcgtcc aagaagcttc ggatggtaca gtaaaatatt tgtttgaact ccctgataaa
    42181 aacatgattg agactgtact gatgagacaa gaatatggct tgtcagtttg tgtgacgaca
    42241 caagtaggat gtaatatcgg ctgtacgttt tgtgcaagcg ggctgctcaa aaagaaccgt
    42301 gatctgactg ctggagaaat tgttgcacag atcatgatgg tccaacatta ttttgatgag
    42361 cgcaatcttg gcgaacgcgt ttcacatgtc gttgtaatgg ggatcggtga gccatttgat
    42421 aattacgaca atgtaatgga ctttttgcat atcatcaatg atgccaaagg attggcaatt
    42481 ggtgctcggc acattacagt ttccactagt ggattagcac acaaaatcaa ggaattcgct
    42541 aataacggct tgcaagtcaa tctggctatt tccttgcacg cgccgaataa tgaggtgcga
    42601 acatcgatca tgcggatcaa ccgaagtttc ccaattgaga aattgatgga agctgtggat
    42661 gagtatttag agaaaacaaa ccgtcgaatc acgtttgaat atatcatgtt gaatcaagta
    42721 aatgatagac cagagcatgc gcaacaatta gcagatctat taaaagataa gaaaaaatta
    42781 gcatatgtca acttgattcc atataatcca gtcagtgaac atgatcaata ttctcgcagt
    42841 ccaaaagctg atgtattgag attttatgat gtattgaaga aaaacggcgt aaactgtgtg
    42901 atacgtaaag aacatggtac agatattgat gcagcttgcg gacaattgcg aagcaagcaa
    42961 atgaaaaaaa cagttgccaa ataatcgtat cctactcgtt ttttcaatta ccataaaagg
    43021 agcagttttc ttaattaagg aactgttcaa cttaaataag agaaaagatt ctatagcgaa
    43081 agctataaag ctttttttga caagaaaaac cctcatcaag caaagaaatg tcctcaattt
    43141 gatgacagcc tgcttgatgg gggttttagc aattatttaa ctgattttct tatatccttg
    43201 ctggctttct tgtgtagcat gataagtttc tacgtcaaga atggcctgtt taaatttttc
    43261 tcgggtgatt tcataaggca catgtttaat atcatttgtt gccatggctt tatctaagat
    43321 tgcttctaaa tcggtcgtga cattgagatt catgtcggtt aacgatactg gaagttggtt
    43381 ctttttcata aacacataga ttttatcaaa caaatcgaac tgctgatcca tcatcaataa
    43441 ggtcagtaca ccataactga cagatgctcc gtgaaggtat ccctccattt tttctagaac
    43501 agtcgtaccg taatagaatg agtgtgccat agcagaatta tagttattgt taactaaaac
    43561 agaaaccaat ccggtagtaa caatgatatc cgaaacgact tgttcaattg catatgaggg
    43621 acgatcgtcg gcactatctt tcaatgcttg cgtaccataa gtcaagagac gatcaatgca
    43681 catttttccg atttggattc ctaatctatc cgtgtagcct agatcatcgc cacgagcaga
    43741 aaaagtagat tcgacttctt tggataaagc atcgccaata cctgcccata agtatttatc
    43801 aggtgcttcg gcaataattg ctgtatcaat gaaggtgtgt acaggtggtt ttgaaggaaa
    43861 gaagagtccg tccattacgc cttcttcgtt atagatgaca cataccgcag tgacgggcga
    43921 acagttcgaa ccaatagtgg gaaaggtgaa gactggttta gctagttttt caccaatgac
    43981 ttttacagta tcgcaagcac ggccaccacc gactgcaaac aggacgtctg ctttttggac
    44041 actttcatgc tggatcaact gttcaatatt tccataagtt gaattacccc cgtaccagag
    44101 actggcgaca acctctattt cctgtgtcaa agctactttt attttgtttt ctgcctttga
    44161 aagtgcagtc ttccctccaa tcagcactac ttttgtccca tattctttga cgattccatt
    44221 tgctttttca tacgcatctg ttccaatggt ataatttggt aagaaaacac tttgactcat
    44281 attcatttcc ttctttcttc gttgaaacgg gttaaaattt taaagagtga tcgatctgac
    44341 tgcggctgta gatggagtag aggtgaacct aagacaggat aagtgatgaa taaggtggca
    44401 tgaacacctt gaaatcatca ataagtatcc taaaaacgaa caagtacaaa aacattgaaa
    44461 acgacaataa tgaatttttg ttcctcttag tatttctacc gattcccttt gcttttttgt
    44521 aattatctaa aaattctaaa aattaagatt attatatgaa aacaggtttt atttgtcaat
    44581 tcataattgg ttttttttaa agcaaaagat aatctatatc atgatgaaca aacagagttt
    44641 tttcctccaa ttgatggctt tcctgatctt tcctattttg aataaagtgt ttctgtataa
    44701 ttttttattt tataagtaag ataaataatg aaagaataga gatactgatt ggtagctaaa
    44761 gatttttgag cgagaacatt tcgttttttc aaaaggactg ttagaataag caagaacaag
    44821 ggggaagacg tatgataatc agtgaatttg accgtaataa tccagtattg aaagatcagc
    44881 tttctgattt actgagactg acttggccgg aagaatatgg agacagctcg gcagaagaag
    44941 tagaagaaat gatgaatcca gaacgaatcg cggtagcagc ggtagaccaa gatgagttag
    45001 taggatttat tggtgcaatc cctcaatacg gtatcacagg ttgggaattg catccattag
    45061 ttgtagaaag ctcccgacga aagaaccaaa taggtactcg attagtcaat tacttagaaa
    45121 aagaagtagc ttccagagga ggaatcacga tttatttagg tacggatgat ttagaccatg
    45181 gaacaacgtt aagtcaaacg gacctgtatg agcatacatt tgataaagtg gcttccatcc
    45241 agaaccttcg tgaacatccg tatgaattct atgaaaaatt aggttataaa atcgtaggtg
    45301 tcttaccaaa tgcaaatggc tgggacaaac cggatatttg gatggcaaaa acgattattc
    45361 ctcgaccaaa ttctcaataa taaaaagagg ttgtgacaga agtaatcagc ttcaagaaat
    45421 aagaaggaat ttacgaaaat tacttcttga atttttgtga aattccaact tatttccgaa
    45481 gaagctactt ttggaacacc gtgtaccaga ggttgtgaaa aagtcgctta gtttcgagta
    45541 gtaagaaaaa ttttgtgaaa atggctttct acatttttgc ataaatttgg cttaataccg
    45601 agaaactggc ttttgaacac cgtttattca gataagggac tgtgacaaga cttttgtcac
    45661 agtttctttt tgtttattct tttttatctt tgtatggcaa taatagacaa tataacgaaa
    45721 attatttaat ggcttttgga agaccatgga aaaccttgta caaagctatt ttttctgaaa
    45781 aattccttga aacctcacga aaaaatcatt attttatgaa aaagacaaaa aaaagtgttg
    45841 attttttaat aattattcat taaactctta aacaacttca gaaaatatta attattctga
    45901 aaattccaat aaaggggtac gtaaaatgaa aaagaaattt acatttggtt tggttgcggt
    45961 atgcggcctt gtacttgctg gatgttatgg cggcagttca gccacaagca gtagttcagc
    46021 aaaaagcggt tcagcagatg gaggaggcgt atttaactta gtcgtgcctc aagaaatgcc
    46081 tacagctgac ttatcagttg caacagatac aatcagtttt acagcattga ataacgttta
    46141 tgaaggaatt taccgtcttg atgaagacag caaaccacag ccggcaggag ctagcgagtt
    46201 ggcagaagtc agtgaagacg gattaactta caaaatcaaa ttacgagaag acgcaaaatg
    46261 gtcaaatggt gatcctgtta cagcagcgga ttacgtttat ggctggcaac gaacagtaga
    46321 cccagctaca gcttctgaat atgcttacct gtatgcgcca gttgaaaatg cagaagacat
    46381 tacagctgga aagaaagata aatcagaact agggatcaaa gcagttggtg actatgaatt
    46441 agaaatcaaa ttgacgaaac aaacaccata tttccaatat ctgcttgctt tcccatcatt
    46501 tttcccacaa aaacaatccg tagtggaaga aaatggggat gcctatgcat ctgcaagtga
    46561 taaagctgtt tataatggac cattcacatt agaagatttt gatggaccag gaacagatac
    46621 agaatggact tataagaaaa atgatcatta ctgggacaaa gatacagtaa aactttctga
    46681 aatcaaagtc agtgtagtaa aagaatcttc tactgcattg aacttattca aagatggcca
    46741 agcagatgac gtgatcttgt ctggtgagtt agcacagcaa aacgcaaacg atccagctta
    46801 tacttctgtt aaagaagcgc ggacaagcta tatcgaattc aatcaacgtg aaaagaattc
    46861 accattcaac aatgtgaacc taagaaaagc tatttcttat tctatcgatc gtgaagcttt
    46921 agtaaaacaa gtactaggtg acggatcagt tgtctctaca ggattgatcc catcagatat
    46981 ggtaaaaagt ccaacaacga acgaagactt tgcaaaagaa gctggaaaat tagtttctta
    47041 tgacaaagat aaagcaaaag aatattggga aaaagcgaaa aaagaattgg gcgttgattc
    47101 tttagaattt gatttgatgg cttctgatga tgattcatcg aaaaaagtaa tcgaatatgt
    47161 tcaaaactca atccaagaaa acttggatgg cgtaacagtc aaaccaacac ctgttccatt
    47221 ctctgtacgt cttgaccgct caacttcggg tgattttgac gcagtactag gcggatgggc
    47281 tgctgactat gcagacccaa gcagctttac tgatttgttt gtcacaggta attcatacaa
    47341 ccgtggtcgc tggagcaatg cagaatatga cgaagcagtt aaagcagctt catcaacaga
    47401 cgctggcgat gaacaagccc gttgggatga tttccaaaaa gcaatcaaga tcatctctga
    47461 tgatatgggt gtcgttccgg tgtaccaaaa agcagaaggt cacctagtga atgaaaaaat
    47521 caaaggtatc gttcaccatg cggcaggcgc ttcatgggat tacaaatgga catacgttga
    47581 agaataatcg ttaataccgt gagcatgaga aaaaacgagg ctgcggcaaa tgtcgcaacc
    47641 tcgttctcat attcacttat cctaacaaag aaaaaagcat gaaaatagca gaaagagcaa
    47701 ttagtattcc ggcaatgatc agccaaaagc tgtacatacc gtagctggca gacgagagcg
    47761 tggaaaattc tggttttttc tttcggttcc ttgttcgtgc aagatggacc gatcgctgaa
    47821 aatgatcgaa gaaacccgaa gaaaagaccc ataaaaaacc gccgataatc agaaacggca
    47881 atgaccataa gaatagatca ttagataatt gaatgagtgt aaaggaatgg ttgatgagat
    47941 tttttattaa aataaccaga atcagtagaa aagctactgc gtaggggata gatttttttt
    48001 tcatttgatt gctcctttat ttttggttca ttatctaata atgtagcgaa acatctgtca
    48061 gaagtcaaaa gctaggggga aacattagtg aatagttata tcaaatatgt attaaaacgt
    48121 gtctttttca tgatcatcac gctttggtta attgcaacaa tcaccttttt cttgatgcaa
    48181 ttgctgccgg gcacgccata tacgaatcag gaacgtttga gtcctgaaac aatcgagatg
    48241 ctaaataaac aagtcggttt ggataaacca gttatcgtac aatatgggat ttatctttct
    48301 aatttgcttc aaggagattt tggaatttcc ttccaattta aaaaccagcc agtcgcacat
    48361 ttgttagctg gaagaatcgg accatccttg cagttagggt tacaggcaat tatctttgga
    48421 acagtcctag ggacgatttt aggaacgatc tctgccatga agcaaaatac atgggcagat
    48481 acatcttcta cactcgtagc gatattaggt cgttccattc caaactttgt atttgctgtt
    48541 ttattacaat atatctttgc aatcaaatta caagttttgc caatcgcaaa atgggatggc
    48601 tttgtgtaca caatcttacc aacaattgcg ttggccatgt cgccgcttgc tgactctgct
    48661 cggtttatcc gtacggaaat ggtggaagta ctgcatagtg attatgtgga attagcaaaa
    48721 gcaaaaggat tgagccgttg ggaaatcgcc tttaaacatg gtcttcgaaa tagtttgatt
    48781 ccattgatga ctttattagg accgttagct gtagcattga tgaccggatc actggtggta
    48841 gaaaatatct ttgctattcc tggtatcggg gaacaattcg ttaagtcaat cacaacaaat
    48901 gattatccta cgatcatggc tgtaacgatc ctttactcat ttatgctgat ttttgttatt
    48961 ttgatcgtgg atctattgta cggtctagtt gatccaagaa ttcgtgtttc agaagggagc
    49021 cgaggataaa tggaaatgat accaaagcgt tatgaaacag ttgcagatat ccctgcggat
    49081 gaatttcttc cattacaaaa aaataccgaa gaagaacgtg aacagattac tgcaccttct
    49141 ttgaatttta tccaagattc atggcgccgt ttaaagaaaa acaaagctgc cgttatttca
    49201 atggttttac tattggtcat cattttgatc tctgtgatca caatctttgt ttctcctcat
    49261 gatccaactg cccaaaacgt ggcttatatc aatttgcctc ctcgtattcc gggaatcaat
    49321 atcgatggat tgaatggaaa agcaatggtt ggtggtgaac ttgttgataa atatgctcaa
    49381 gcaaacgtcc cttcaaacgt aaatttcttt ttaggaacag acggtttggg acgtgatgta
    49441 ttaagccgct tatttatggg aatgagaatc tcgttgctga tcgcatttat tgctgcatta
    49501 ctagatgtaa cgattggtgt agcttacggg ttggtttctg gtttgttagg cggacgtgtc
    49561 gataacgtga tgcaacgttt tttggaaatc ttatcaggaa ttccaaacct cgttgtcatg
    49621 attttgatgt tggtcgtttt tgaaccagga attttttcaa tcgtggctgc tatggccatc
    49681 acaaactgga taccaatggc acgtatcgtt cgtgcacaaa caatgaaatt aaaagatcaa
    49741 gaatatgttt tagctggatt gacattaggt gaatcaagaa tgaaaattgc attcaaacat
    49801 attttgccga atatctctag tgtcattatt attcaaatga tgtttagtat tccatctgct
    49861 attttcttcg aagccttttt aagctttatc ggtttaggtc ttacgcctcc gtcagcttca
    49921 ttaggaacga tgttgagcga agggtacaag acattcctgt atctgcctta tctattatgg
    49981 attccggcag taactttatc ggttatcatg attggcttta acttacttgc tgatggattg
    50041 cgtgatgcct ttgatcctaa aatgaaagag tgaagacgat gacgaaaatt ttagaagtga
    50101 aagacttaga aatctctttt gatacgtatg ctggaaaggt acgagcgatt cgcggtgtca
    50161 attttcattt gaataaagga gaaacattgg cgatcgttgg ggaatctgga agtggaaaat
    50221 cagtgacgac cagaagcatc atgcgcttgc tgtcaagcaa cgccaatata gatgctggtc
    50281 aaatcctctt taaaggtaac gatatcgttg gaaaatcaga aagagagatg caaaaaatcc
    50341 gtggtaaaga aatagcgatg attttccaag atccaatgac ctctttagat ccgacgatgc
    50401 ccattgggaa gcaagtcgct gagtccctta gaaagcataa taaagtttca aaaaaagagg
    50461 gacaaaaagc tgcattagaa ttgcttaaat tagttggaat acccgaagct gagaaacgta
    50521 tcaacagtta tccgcatcag ttctcaggag gtcagcgtca acggatcgtg atcgcgattg
    50581 cactggtatg ttatccggaa atcctgattg ctgatgaacc tacaacagcg cttgatgtga
    50641 ctattcaagc acagattttg gagctgctga aagaaattca gacaaaaatc gatacatcaa
    50701 ttatctttat cactcatgac cttggtgtag tagcgaatgt cgctgatcgt gtcgctgtca
    50761 tgtatggagg aagaatcgtt gaagttggaa catcggaaga aattttctac aacccgcaac
    50821 atccctatac ttggggactg cttggttcaa tgccgacatt agatagtgcg aacgatcgat
    50881 tgtatgctat tcctggttct ccaccggatt tattgaaccc gccaaaagga gacgcattct
    50941 atccaagaaa tgaattcgcg atgaaaatcg atgcagaaca agaaccacca ttttttgaac
    51001 tatcaaaaac acacaaggca gcaacttggc tacttgctcc gcaggcaccc aaagtgacac
    51061 cgccagaaga aatccaacgt cgctgggcta tctttaaaga gaaacaaaaa catacttacg
    51121 gtcaaggagg aattgctgat gccaaataaa ctacttgaag ttaaaggatt gaaacagtat
    51181 ttcaatgtag gaaaaaagaa tgaagtacat gctgtaaatg acatcagctt tcacatttat
    51241 gaaggagaaa cattcggttt agttggagaa tctggaagcg gaaaatccac tactggccgt
    51301 acgatcattc gcttgaatga acctactgat ggtgagatat tattcgacgg tcaagatata
    51361 acgaagatca aagataaaaa aggtttgacg aaattccggc atgatgttca gatgatcttt
    51421 caagatccat acgcttcgtt gaatcctcgt atgaaagtca gagatatcat tgccgaagga
    51481 attgatgtta atggactagc taaatcatct gaagagcgtg caaaaaaagt cgatgatcta
    51541 ttgagaactg ttggattgaa tccaagccac ggtactcgtt atcctcatga attttcaggt
    51601 gggcaacgcc agcgtattgg tattgcacga gcattggcag taaaaccgcg ttttatcatt
    51661 tgtgatgaac caatttctgc actagatgtg tcgatccaag cccaagtggt caatttgttg
    51721 caagatctcc aaaaagaaca tcaattgacc tatctattta ttgcacatga tttgtcgatg
    51781 gttaaacata ttagtgaccg aatcggtgta atgcataacg gcttgttatt agagatggga
    51841 acaagtgatg aaatctataa tcacggtgtt catccttata cagaaagttt gttatctgct
    51901 attcctctac cagatccaga ccatgagaga aaacgcagaa gaatcaaata tcaacctgaa
    51961 ccagatgacg gacaagtacg tcaacttcgt gaaatcgcac cagaacattt tgtctatgca
    52021 actgagcagg aagtcccata ttacgcaaaa aaactaaaac gacaaaagga atctcttctg
    52081 gttgctaact aggagggaca tagatgctaa aagcttttaa attccgtatg tatccgacag
    52141 aagaacaaaa acagcaattg attcgtactt ttggatgtgc tcgatttacc tataaccatt
    52201 tgctgaaaaa gcggcagaaa agttggcaac aaacaggagt agccaatttt tcgctcacac
    52261 ccgctacatt aaaaaaagaa tacccattct taaaagaagt agacagtctt gctttagcaa
    52321 atgcacagct taatttggat cgggcttttc gcaattattt caagggacgt gccagcttcc
    52381 caaagcttaa aacgaaaaaa agtatgtggc aatcttatac gaccaacaac caaacccgta
    52441 cgatctatct ggaaaatggc tacttaaagt taccaaaaca aaaagaacta atcaagataa
    52501 atcagcatcg gccagttgaa ggatcgattc gctccgctac gatttctgct cgatataatg
    52561 aagaatttta tgtcgcacta ctttgtgatg tttcgccagt aaaaaaagaa tctttagcta
    52621 aatggatcgg gatcgcctat catccgaaga cattgatcca aacatctcga cctctagaag
    52681 taactttacc aaaatttcac cagacagaag aaaagctgca acatgcacag cggaaattga
    52741 atgtgaaagt ccgctccgct caccatagaa agatcaggtt agatcaggca agcaattatc
    52801 agaaacaaaa gagaaaagta atggatcttt atctgaaaca aaagaaccag cgagaagatt
    52861 atcttgaaca attatctggg aaattggtca aacaatatga ctacttattt gtagaatctt
    52921 ttccaaaaga agaggcacat gctgattttt ctattcacga ctggcataaa ttaataacaa
    52981 aattgcgtta taagtcccaa tggtataata aaaaatttct tttgatcaat accgacggag
    53041 cagaagaaag caattccgta agaaagagcc aagtagtaga aaaaatgggc agacattcgg
    53101 ttatcaaggg ataaaaaatg aatgaaactg ataggagcgt tagggttagc cttgttaata
    53161 aaaagtctta atgacttttg tttctaggaa tttttctttt gaagaaaagc tcactaatta
    53221 tgacaaacca ataaaacaat agcagaaaaa gttcgtacga gctttttctg ctattgttaa
    53281 ttttttattc agaaagttta cgaatacatc aaaattctga aacaaaaaac gtaactcaca
    53341 aagagttgtt tttgcgtttt ttcttgaatg attaggtctg aatcttttgc tcacaacctt
    53401 attcatggtg ccccggcttg agctgataga tttttgaagg acggccgatt cctacaggac
    53461 gttcaccgat ctcatcgaaa tattggagca tagctttctt aaaattggaa tgatcgatcg
    53521 ttttataatc gatccctaag aatttagcaa atacttttcg agcttccgta atcgtgaaat
    53581 ctttacctaa aacttgtaga acttgcggct cgtgttccat tttattgact acacggttga
    53641 atgctttcaa gatgatttga ctatggtcaa aagccaaagt atctttgcca gaagactctc
    53701 cagtgactaa atcaagcgag atagccactt ctccgctaga taaatggatc ttgttactat
    53761 gacgttctag tgtgaaccag cgtacttcct tggcatcatc tccggcgatt agcggttctt
    53821 ctccaataaa ggctaagtag ctgactgtga cgacccagcc tcgcggatct cgattaggcg
    53881 tactgaatgt atgcagttgc tcaatatttt cttttgaaat aaccacacca gtttcttcct
    53941 ttgtttctct taagacgctt tctccagttg actcatcctt ttggacaaag ccaccaggca
    54001 atgcccatga atttcgataa ggatgccctt ttctttggat caacaaaact ttcagctgat
    54061 cttcttcttt gttatagcac atcagtacga tatcgacagt caaagagggc ttgtcatatt
    54121 ctggacgttc ctgtttttga taccagttaa gaaattcttc ttcacttgct ttatgttcat
    54181 aatataattt ttcttcttct ttagaagcaa aacggttcat ctgaccacct ccattgacag
    54241 taaaagtact ttttacctta ttgtagcaga ctctgaaaaa aaaccaagga tttacttgaa
    54301 aaatctaggt tatcatttaa atatgaaaaa taaatggaag tatgagattg aataaaaaga
    54361 aaagcagata aaacggcaat actttatacc gctcttcacg aatggcaaag aagccacaaa
    54421 taacgatata tacgtcaatg ataaaacgca aaatccaagc tgctgtcata aaactgttca
    54481 aatgcccatg gaggttaaaa taaccataca tacgaatata aaaatagctg aatattaaat
    54541 gtgctaatga aagaaaagca atactaagtg taaaaaaaag atgtttcttc tgcatgattg
    54601 ttccagtccc ttactaagat agatagtctt tattatacca cgtgtgaggg gagaaataaa
    54661 aagccgtttt ttagtagata tgaaacaaaa caaaaacccg catttattca acctattcat
    54721 ccttttaaag gatagattga acgtagatag aagtcgttta tccagtcttt ttcattttga
    54781 aaaaaagcta acagcatgct ttttttatgg tatactagca aggaaacgaa ttcgcatcat
    54841 gcgataaagg aggaagagcc ccgtggcaga aaaggaaact ttttatatca ctacgccaat
    54901 ctattatcca agcggcaaac ttcatatcgg caactcgtat actacgattg catgtgacgc
    54961 aattgctcgt tataaacggt tgatgggctt tgatgtgttt tatctcactg gagtggatga
    55021 acatggtcaa aaaatcgaaa caaaagcaga agaactaggt gtaaaaccgc aagaatatgt
    55081 agataaaatg gcggctgatg tcaagaaatt atggaaaacg cttgatatca gttatgataa
    55141 attcattcgc acgacagatg attaccataa agcagctgtt caaaaaatat ttgatcgttt
    55201 attagaacag ggagatattt acttaggtga atatgaaggc tggtactctg tttctgacga
    55261 agaattcttt acagaaacac aacttgcaga agtgtacaaa gatgacgaag gtaacgtgat
    55321 cggtggtaaa gcgccaagtg gacacgaagt agaattggta aaagaagaat catacttctt
    55381 ccgcatgagc aaatacgcag accgtctatt ggaatactat gaagaacatc ccgaattcat
    55441 ccagccagaa tctcgtaaaa acgaaatgat caacaacttt atcaaaccag gattagagga
    55501 tcttgcagtt tcacgaacaa cttttacttg gggagtacca gtcaagagtg atccgaaaca
    55561 tgtggtgtat gtatggatcg atgcattatc caattatatt actgcactag gatatggctc
    55621 cgaagatgaa agtctattcg aaaaatactg gcctgcagat gttcagatgg tcggtaaaga
    55681 aatcgttcgc tttcatacga tctattggcc aatcatgctg atggcccttg atttgcctct
    55741 acctaaaaaa gtatttgggc atggctggct attgatgaaa gacggaaaaa tgtctaaatc
    55801 aaaaggaaat gtcgtttatc ctgaaatgct tgtggaacgt tatggtttag atgcactccg
    55861 ttattatttg cttcgtgctg ttccgtttgg gtcagatggt gtctttacgc cagaagattt
    55921 tgtttcccgt gtcaattatg atctggcaaa tgatctaggg aacttattga atcgaacgat
    55981 tgctatgatc aacaaatatt gtgatggact cgttcctgac tatgcctcac ttgtcactcc
    56041 atttgatagt gaactgtcta cgacggctgc taacgttgtc ggacgttacc atgatgcaat
    56101 ggaaaaaatg gaattcaata cagcattggc tgaaatctgg gtgctgattt ctcgtgcaaa
    56161 caaatacatt gatgaaacag aaccatgggt attagcaaaa gacgaagaaa agaaagctga
    56221 attgaatagt gtcatgatcc atttagctga atctttgcgt atcgcagcga tattacttca
    56281 gccaatcatg acagaaacgc cagagaagat cttcaatcaa ctaggattgg actctgaaac
    56341 aatgaatctt gaaggattac actttggcga atttccttca ggaacaaaag tagttgcaaa
    56401 aggtacacca atcttcccac gtttagatat ggaagaagaa gttgctttta ttcaagaaaa
    56461 aatgtctgaa ggtactcaaa caaacgaaga tacagtcaaa tgggatccag aagaaacaga
    56521 acttgtttca acgaaagaaa aacaaatcaa atttgatgta tttgaaaaag tagaactaaa
    56581 agtagcagaa gtcatcaact gtcaaaaagt agaaggggca gataagttgc tgcaattccg
    56641 actagatgct ggagacagcc aagaccgtca aatcttgtca ggaatcgctg aattttatcc
    56701 tgatccaagc gaattgatcg ggaaaaaagt cgtcattgta gcaaatctga aaccacgaaa
    56761 gatgcgtgga caaatcagtc aaggaatgat cctttctgca gaagcaccag atggctcttt
    56821 acaagtaatc gaagcaccaa aatccatgcc aaatggctca gaaatcgcat agaaattcaa
    56881 agggggtatg acactagttg tgtcataccc cctttttccg aaatttgaga agcaattttc
    56941 gtaaattcct tcttattact tgaagccaat catataatac agaaacagag aactatccaa
    57001 aataaatcct agaaaaagaa gtacgagctt cgctgatttt tgttaattta gaataatact
    57061 aataggaatc gtaaaaacag aaaaaaagca taatgataaa gggtcgggca gattttaatt
    57121 gattcatctg gtactctttt ttattgtcct tacattcata aagtttgaat gcaatgactt
    57181 tattacatct atatttatat ctaacagtag cgttgatgtg ttaattataa gttctatcac
    57241 tttatgttca attagtttgt gctcttatat gtgtgattga aaatatagat aaaaaaacaa
    57301 tcatcggctt tgacttcgat gattgttttc tttattttgt aaaaatccta tcacttgatt
    57361 ttatggtaac cttttatttt tgtcttcaaa cggcttggta agagagcagt aagcagtgca
    57421 aatgggatcg aaaagacata ccagaaaatc gtacgtccga taccataatg ttgatagagc
    57481 tttgtcaaca tcacgtgtaa caagatcaac cctaaaagca aggagccagc tataaaccaa
    57541 tgattatccc aatgcatgac ttcactaagt gccatcactc caaaaggata gaaataaaaa
    57601 tagatcccga ctaaggtcat ccgccagttc tttgtaaatg ttccgatatt caataaaaag
    57661 aaaatcgctg aaagcaaaat accgataggc ggaaaaagcc caaccaaaaa ggaatacaac
    57721 atcccccaca agatcatcac aggacctttg atcaatgcaa cgattgcgat gaacaaagtc
    57781 agcaatatta gtttttgtga taacgttgca acagtcatta atccaaataa aattaatgtg
    57841 aaccaatgcc aatgggactg ctgttgttct ttacgggaaa aatcgacccg gttggataaa
    57901 taatctgcta atttcggata agaacgctta aaatccataa actgttcctc cttcgtggaa
    57961 aaggtaggtt tagtatacga aaaataaaaa agaaatacat ccgtcttaag agggagtttt
    58021 tcactgaaag tggagaaaaa agaatggtaa attaaaatat tctcagttat actgaaaatt
    58081 ataccaaatt tcaaagaaga aagaggatgg gaatgaaagg caaactaaaa cgagaaatca
    58141 atctgtttgg cgcattagct accgttatgg gaaccgtgat cggtgcaggc gtcttcttca
    58201 aaactgctgc tgttactgct agtactcagt ctacaagttt gacattgcta gcttggcttt
    58261 tgggtggttt cttaacgatc tgtgctggat tgacagtggc tgaattagct acagcaatcc
    58321 cggaaactgg tggagctgta aaatatattg aagctgcgta tggaaaattg cccagctttt
    58381 tattaggatg ggcgcaaagc ttgatttact ttcctgctaa tattgctgca ttatcgatta
    58441 tctttgcgac acaattgacg aacttattac aattatctac cgattatctt ttgttgattg
    58501 cagtgatcac cgctgtttct gtgacagggt tgaatttgtt agggacaaaa gtcggtgctt
    58561 ctgtacaatc agtgacgttg attgttaaat taataccaat tgctgtgatt gtcatatggg
    58621 gattattgac cccaggacaa ggaactgtcc agttatttcc aatcgaagct ggaaaagatg
    58681 ttacttttgt cgaaggattg agcagtgcgt tgttagcaac gttgtttgct tatgacggct
    58741 ggttaggtgt cggtgcaatg gcaggggaaa tgaaacggcc ggaaaaagat ttgcctaaag
    58801 caattattct tggtttgagt tttgtaacag tcgtttatct attgatcaat tttgtttttt
    58861 tgaaaacttt gccgattgat catcttgccg gtaatttgaa tgcagcttct gaagcatcag
    58921 acgtcatttt tggaggaatc ggtggaaagc tggtcactat tgggatcttg atctcggtat
    58981 acggtgcatt gaacggttat acactaactg ggatccgcgt gccttatgcg atggctttag
    59041 aagacgagct acctttcagt aaacagctga caaagctttc aaagaagttt acggttcctt
    59101 atgttcctgc ggttttccag ttagcagtag cttgtattat gatgagcctt ggttctttcg
    59161 actttttaac agacatgttg atttttgtga tgtggctatt cagtttactg atttttatcg
    59221 gtgtctttat tttaagaaaa aaagcgccgg aattgccacg tccatataaa gtaccacttt
    59281 atccaatcgt tccgattatt gcgattctcg gtgctatttt cattttaggt atgacgatga
    59341 tgacgcaaac gaaattagca ttgatcggta taggtgttac cttgataggt atcccagtct
    59401 attatcaaaa aaagaaaaaa cgctcagaag agtaaaatat ttcaacaaca gacagaaaaa
    59461 gtacgaacta ggtcctctag atcttcgtgc tttttctatt tcaataaaac aagttcttct
    59521 attttgattt ttgctacttc tgcaagtagt gcttatgtgc taaagtaaga atgaaaagga
    59581 gagataaaca tgatatttga ttctcatacc catttaaatg ctgaacagtt caatgaagat
    59641 attccagaaa cgattcagcg agcacaagaa atgggggtaa cgaaaatggc ggtcgtgggc
    59701 ttcgatacgc caacgattga aaagtctttg caattaagcc atgactatcc aaatatatac
    59761 agtattatcg gctggcatcc gacagaggct ggcagttata cgaaagaaat cgaaaataaa
    59821 ttacaagaac aattgacttt accaaaggtt gtagcattag gggaaattgg cttggattat
    59881 cattggatgg aagacccgaa agaagtccaa gataaagtat ttcgcagaca gattgctatc
    59941 gcaaaagaaa tgaacctacc aatcagtatt catactagag aagcacttga agacacgtat
    60001 caaatcctaa aagaagaaga tgttcgagat atcggtggaa tcatgcatag tttcagtggt
    60061 gattatgaat gggcaaaacg atttcttgac ttagggatgc atatttcatt tagcggtgtc
    60121 gtcactttca aaaaagcatt agacgtccaa gaggctgcag caaatgtacc aatcgaacga
    60181 ttacttgtgg aaacagatgc cccttatctg gcaccagttc cttttagagg aaagcgaaat
    60241 gaaccaggct atactcgtta tacagtagaa aagattgctg aacttcggaa tcttccgaca
    60301 gaagaagtgg ctgcccaaac atggacaaat gcgcaccgat tatttggtct aagcgaacat
    60361 ggataagatg aagatccaag agattatagt cgttgaagga aaagacgata caagaaggct
    60421 gcgggaagta gttgatgcag atacgataga aacaataggg tctgcaatca atgaagagat
    60481 cctgatgcaa attgaacatg cccaagagac tcgtggagtg atcgttttta ccgatcctga
    60541 tttttcagga gaaaaaataa gaaaaatcat tatggaagct gttcctcagg caaaacatgc
    60601 ttttttgccg cgcacacaag ctaaaccaaa gaaaaaggga agccttggtg tcgagcatgc
    60661 aagtgatgct gctattttag aagcattgaa aaaggtcgtg acgccagaca tttcccaaac
    60721 ggctgtttct gaaatcacta gacaagacct tttagactat ggtttaatag ctggggcaca
    60781 agcaaaagaa aaacgagaaa aactaggtga cgagttgcgc atcggttaca cgaacggcaa
    60841 acaattggaa aaacgtttga agatgtttcg tattacgccg aaagaactcg cccaagcaat
    60901 gaaaatagtg gaggaacaac atgagtgaat atcgtgaaat tgcgacaccc tctagaacaa
    60961 aagagatttt attgaaacat ggtttttcat ttaaaaaaag tttaggacaa aattttctga
    61021 ctgaaccaaa tattttaagg aaaatcgtag aaactgcgca aatagatgaa catacgaacg
    61081 tgatcgaagt tggaccagga atcggtgcat tgacggaaca attagccaag catgcaaaac
    61141 aagtcgtagc atttgagatc gatgatcgtt tgatccctgt attggctgat acgatgcaac
    61201 cctatgacaa tgtgactatt gtacatcaag atattttaaa gaccgatttg tcaacagctg
    61261 ttagagaaac atttcatgag gagcttccgt taaaagtcgt agcgaattta ccttactata
    61321 ttacgacacc gatcatgatg cattttcttg aatcagattt ggttgtggat gaactagtcg
    61381 tcatgatgca aaaagaagta gctgatcgta tctctgctga accaggaacg aaagcttatg
    61441 gttcattatc gattgctgtt caatattata tggaagccag tttagcattc atcgtaccaa
    61501 aaacagtatt tgtccctcag ccaaatgtag attcagcgat tttgaaactg acaagaagag
    61561 atataccggc agtcgaagtg acagacgaaa aagcattttt ccgattgaca aaagcggcat
    61621 ttcagcaaag aagaaaaacg ctttggaata acttgcagca ttcgtatggc aaagatgacc
    61681 agacaaaagc atggttagca aaaagcttgg aaacagctgg aatcgatcca aaacgtcgtg
    61741 gggagacttt gtcattacaa gaattcgccg cattaagcaa tgcgatgtca gaaaatatgc
    61801 agtaaaaaaa gaggttgtga cagaagttgt gaaaaagctg tcctgcatca agtaataaga
    61861 acagccaaac aaaaatagtt cctcatgttt ttcgtttgtt tgggcttatt accgcagatg
    61921 caagcttttg aacaccgttt aagaaagagg ttgtgggcct gccgtttaac tctaagtcac
    61981 aaggaacaat ttcaaaaaac agcttctcat gtttttgagt tagttggtct tattacttga
    62041 tgcaagcttt tgaccactat tatgccgaac aaggagatgt gacacaaatt ttgtcacatc
    62101 tcctattttt gtttcttgat caaaaaattc ttatacttga tactcacact cattttgtat
    62161 ggatttagaa aagaatatgt gtcttgacag ttattagtaa gtgagttata ctaagtcgac
    62221 atttatgtgt caagacatat taggagagag aaaaaatgag aaaaaattca gttcgaaaac
    62281 taacgatttc tgctttattg attgggatgg gggtcattat cccaatggtc atgcctaaaa
    62341 tcatgattcc accagcttcc tttactttgg cgtctcatgt gccattattt attgcgatgt
    62401 tttttacacc aggagttgca gtggctgttg cgctaggtac gacatttggt ttctttttaa
    62461 caacgccggt tatcatcgca ttgcgagcat tgtcacatct tgtgtttgcg ttgattgggg
    62521 cttggtactt gcaaaagcat ccgagtatcg ttttaaaaaa tggacagttt acttttgcta
    62581 attggcgttt ccaagggttc aattttgtga tcggtgtgat tcattcttta gcagaaatgc
    62641 tagtagtcag catcttttac tttattggta atatgcctga aacatattat tctcaaggat
    62701 atttttatac agtattcatc ttgatgggga ttggtgggct tatccacagt ttagttgatt
    62761 ataatattgc ttattttata gcaggaacac tcagcaaata ttttgatatc cccgtattta
    62821 cggcagcaaa aaaagaaaat cggaaagagt cgattcaagg gtacgcgaag aaaacgacat
    62881 attagacatg atctctcaaa aaaaaaactc tcatctagta atggataata aatcctctaa
    62941 gatgagagtt ttttgtccta aaaagagctg caccaacatc ttctggcaca gctctaacag
    63001 ggggcaattt atggaagttt gatgacttgt tctgtttctt tatcaaagaa gtggcctttg
    63061 ctgatgttga aggcaaggtc gactatttcg cctggtttat ggaaatctct tgcatctact
    63121 tttgagatga actcagtaga accagttttt gtgtaaagca tcgtttcagc tccaagtaat
    63181 tcggaaacga caacttctga tttcactacg gcttcaggtg aagcttcaag ggctacttgt
    63241 tcactgtgga tgtcttctgg acgaataccg aagataactt cttttccttc ataacctttt
    63301 tcaactaata ctttgttttt tccttcagga atacgaagct taagcccatg tccatctgtg
    63361 ataacaccat ttttcaatgt cacattaaag aagttcatgg caggagatcc aataaagccg
    63421 gcaacgaaca tattgacggg tgtatcataa acttctttcg gtgtaccgat ttgttggata
    63481 aatccgtctt tcatgataac gattcggtca gccatagtca ttgcttctgt ctgatcgtga
    63541 gtaacataga tggtcgttgt ttcaagacgc tggtgaagtt tggcaatctc agcacgcatg
    63601 gctacacgta atttagcatc taaatttgat aatggctcat ccattaagaa gacttttgca
    63661 tcccgaacga ttgcccgtcc caatgccaca cgttggcgtt gtccaccaga taaagcagct
    63721 ggttttcgtt tcaagtattc tgtcagacct aagatctctg ctgcattgtc cacacgtttt
    63781 ttgatgtctg ctttatcata tttacgtaat ttcaagccaa aagccatatt atcaaaaaca
    63841 gtcatatgag gatacaatgc gtagttttgg aaaaccatgg caatatcacg gtctttaggt
    63901 gccacgtcat tcatgacttt tccgccgata tttagttctc cttcagagat atcttccagt
    63961 cccgcgatca ttcgcaaagt agttgacttt ccacaaccgg aaggaccaac aaaaacgata
    64021 aattcacggt ctttgattga tagattaaaa tcagttacag aataattttc tgcattgtca
    64081 tattttttat atacgttttt cagagccatt tctaccataa tacgttccac actttctttt
    64141 ttagttttat taactattta aagtataaat gaaagcgtta actaacttca atgtcatgtt
    64201 gaacaagaat tttttctttt ttttgtcaat gtgctagttt taagctttaa taaatatcca
    64261 taagaaataa aaactgatac actggagtaa ataagtatgt taacaatatc aaaaggagtg
    64321 tctcttatga aaatcgcttt gatcgctcat gaccgaaaaa aacctatgat ggtgaaatta
    64381 gcaacagcgt ataaaacaat attggaaaaa catgaacttt ttgctaccgg gacgactggg
    64441 cagaggatca cggaagcaac cggcttgccg atccatcggt ttaaatccgg accgttaggc
    64501 ggggatcagc aaattggagc catgatttcg gaggatcagt tagatttggt gatttttctt
    64561 cgagacccgc tggctgcaca gccccatgaa ccagatgtaa cagcacttat ccgtttatct
    64621 gatgtctatg agattccgtt agctacgaat atcggaacag ctgaggtgct actaagagga
    64681 ctggaagccg gcttcctaga ttttcgaaga atcgtccatg aaatagacaa gcatccactt
    64741 tcattttgat ggataagcgt atggaaaaat aacgtttaat gttcgcctat atgtagctat
    64801 aaaagctaaa caaactgata atatgcgata taatacgaac gtattggata atataaacaa
    64861 taatattagt ttttcgtatt tgcagtaaat gtgaaaatat gctatagttt ctgtgggaaa
    64921 agatcccaaa aataatacag agtagaaaat aaagcgttaa gtgctaagag gatgggatgt
    64981 tgcctcttgg acgaaggacg taatgttcgc ggttttattt tcgcattcgc tgcatgatac
    65041 gatgtagcag ctcttaaagg agatgctaaa aatgaagaaa caccggttag acgcacgtat
    65101 gattgctatt atgggcttat tgattgcatt gatggtcact ttgtcccgac tggtagcaat
    65161 cgagacccca tttattaaaa tcagtgtcac atttattcca caagtgatca tgggcattct
    65221 ttttggtcct ttttggtcag ggataggcgc agttttagct gatttagtag gaatggccct
    65281 cttctcgaaa tctgcattct ttattggatt tacattgaat gcatttattg aaggagcaat
    65341 ctacggattc tttttctatc gaaaagagat cacttggaaa aatgccattc tggctacgct
    65401 tagtgtcacg ctgatcatca acttattttt gacaccatta tggcttgcgt tgatgtacca
    65461 tgtgccattg ttcagctggg tcgtttgggc gccccgcctg ttaaaaacag taatatggtt
    65521 accgattcaa tcaattgcca tttattacgt aggacgtagt attccttaca aaaaaatttt
    65581 aagaagttta gcgatccacg ctaaataaaa aacaagcagt cttcccatcc cagaagactg
    65641 cttgttttta ttgtgctgtg aattgtgctt gatagagccg tcggtaataa ccatcttttt
    65701 gaagcagctc atcatgggtg cccatttcga caatagctcc ctgatccatc actaatatct
    65761 ggtccgcatt tttgattgtg gacaggcgat gggcaatcac aaaactggtt tttccttcca
    65821 tcattgctaa gaaggcttgt tggatttttt tctctgtcaa tgtatcgact gagctggtag
    65881 cttcatctaa gatcaacata gggggattac tgatcatcgt tcgagcaatc gtcaacagtt
    65941 ggcgttgtcc atctgatatc tttaaccctt gaccgccaat cttagtatct aatttttccg
    66001 gcaaacgttc tacaaattca tacatataag aggcttttag ggcatcattg atttctgcgt
    66061 cacttgcttc cggattccca aaacgaagat tttctcgcaa tgtactgtca aatagccaag
    66121 tatcttgtaa caccattcca aaacttttac gtaatgtatc acgttggata gagcggatgt
    66181 catggtcatc gactgtaatt gttccttttg ttgtgtcata aaaacgcatc agcaaattaa
    66241 caagtgtgga ttttccggcc cctgtttttc ctactatagc aatggtttga cctggataag
    66301 cagtaaaatt gaaatcttcg atcaaacgct gcttggggtc ataagaaaaa gaaacatgat
    66361 caaaagagac ttttcctttg atatttttgg gttccaaggc ataggcatct ggcaaatcag
    66421 gcttttcttc tggctgatcg atcaaatcaa atgctcgttc tagaccagaa aaagcggttt
    66481 gcagttgtgt cgtgattcca gaaagttcga taaatggttt agaaaactga cttgagtaga
    66541 tcgtaaagct ggaaatcaca ccaacagtga ttgacgaacc actcttcaat gccaataggc
    66601 cgccaactaa accaatcgat aaataagcaa ggtgatctac aaaacgagaa gacgggtttg
    66661 tcaaggaaga agaaaattgt gcccgttgtc ctttttcata tagatcagca tttagcagtt
    66721 caaattgctg ttgactagct tcttcttgct gaaaagcttt cacgattttc tggttaccga
    66781 ttcgttcggt cacaaagccc gagatatccc caataatcct ttgctgtcta tcgaaatttg
    66841 tttgtgaagc acgagcaacg atccaactca caaggaaaat aattggtgta gaacaaagaa
    66901 cgaccaatgt cagaagtgga cttagacgca tcataaaaat aaacgaaaga atgatgattg
    66961 ccactccaga aaataattga ttgaaggccg cagaaattgc aatggaaata ttgtccatat
    67021 catttgtaaa tcgactgacg atatttccgt gggagttttg atcataataa cgaagtggca
    67081 atcgattcag atgagcaaat gcatcttttc ttaattttgc aacggataag taagctaacc
    67141 gattgcttaa cacttggatg agccattgac tgactacgtt gattaaaacg ataccaccga
    67201 atagaataag taaatggaac agtcgattga agcggacctg tccttctcca atcatttgat
    67261 cgatactttg accaatttgt aacgtcatca caactgttgc aatcccattg atgattccta
    67321 gtatcacagc tagccaaatg tcttttgcat aggcagtaag gtaaggaatg aatcggcgga
    67381 gcgtctgcaa ggataatttt tttactttca taactattct tcctcctgtg atgcgacgat
    67441 ttcctgatat tctgctgatt gagcaagtaa ttcttcatgg gtaccctgag cagcaatctt
    67501 accttgatcc atcactaaga tatgatgtgc ttcttgaata gagcggacac gttgggagat
    67561 aataatcact gtactgccaa gataagtctg tagcgcctta cgcaaatcca agtctgtttg
    67621 ataatccaac gcacttaaag agtcatctaa aatcagtaat gctggcttgg caatcaaagc
    67681 tcttgcaatc gtcagtcgct gtttttgtcc gccagagaaa tttttcccat tttccatgac
    67741 ttttgtatct aaaccatttg gaagctgacg gacaaattct tctgcctgag cgattttcag
    67801 agcttcccaa cattcttttt ctgtggcgtc tttcttaccc cattgaaggt tttcacgaat
    67861 agtcccggta aatagtacag aagtttgggg aacaagagca atttgctgac ggagatgatc
    67921 cagctgccaa gaacgaacat ccattccgtc cattataact gtaccggaac tgacatcata
    67981 gaaacgcgga atcaattgtg tcaaagtcgt tttcccgctt ccggttggac caatgattcc
    68041 aaggactgta tttcgcttca gctgaaatgt aatattttgg agagaaagac cagaatcagg
    68101 agtataacgg aagtcaacat ggtcaaaagc gataattgct tcagaagaaa aatcgggagt
    68161 agtactgacc tcagcttcaa gaatcgaatt ttctgtgtct agcacctctt tcacccgatt
    68221 tcctgaagct tcggcacgtg tgaagatcac gacgaggttt gaaacaacga tcagtgccaa
    68281 aagcatttga ttcatataat tgatcaaagc aagaacttgt ccttgttgca agctaccaat
    68341 atttactttg atcccgccaa ctgtcagcaa acagatgatc ccgacattca tgatcaaggt
    68401 tgtagcaggt gataataggg cagagatatt ggaaacacgt aaataattgt tcgctagatc
    68461 atttgtgctt ttatcgaact tctctgtttc tttttttgtc tgcgcaaatg cgcggatgac
    68521 acgaacaccg ctaagattct gactaacgtg ttcattgagc tgatctagtt tttcttgcac
    68581 tttttggtag agaggaacgg tttttttgat gataaaaaat aaaatgattg agaaaatagg
    68641 caataatgct aagaaaaaca gacctacttc ccagtcgatc acaaaagcca tgaccactga
    68701 cccgatactt aaaaacggtg ctctgatcaa taaacgaatg accattgcta aagctagctg
    68761 aagctgattg atgtcgtttg tcattcgggt gatcaaggta tctgttccaa aatgattcaa
    68821 ctcgttgtga gagaaagtat tgattttttt gattagctga ttacgtaact ctgtaccaaa
    68881 tccttgtgaa gctactgaag catagtattg gcaaatgata gcacaaatca gaccaatcac
    68941 agacatagcg accatccata agcccatttc aatgattttt cctcggtcat tcatttttag
    69001 tccattatcg atcaaggaag ccatcattaa aggcaggaca agttcgaaga cagcttcaag
    69061 aaatttgaag aacgggccca aaatgatttg cttacgatag tcttttgcat aacgtaataa
    69121 ctgaatcata tgattcctcc tattatttat ttgtccacaa ttgaaaaaac aagtactacc
    69181 acattgtagc ttaggaaatt tagaatgaaa agagaacaag ccttttcata aatgaaagtt
    69241 ttattatgaa gaagctttag aaattgaata gactattttt tttaaaaaaa agaaaatgag
    69301 aaaacatgcc agtctcttca ttcataggaa cgtctatttt acttaatttt tctataaatg
    69361 aattctgcat aaaaaatata tcaagtaaat gtttatagat gaaactctat ttacttcttt
    69421 tttaatttgt tcttgcaatc ttttttgcta cgtaattttt gtaaaaaagt gggttgagag
    69481 aaatctaatt gattttcaaa gaaggagtat gaaaatgaga aaaatattta ttcgtttatt
    69541 gtgggtacta tcttagagga ataaataata gtggagaaaa ctatggtttg gcgcagattc
    69601 tatcaggttt gatggaacga agacaacctc ccgacatcaa gtcaaaagcc acttgagatt
    69661 ttgatctgaa aataaaaaaa gaaaacaagg taggaacatc aatgtttcta ccttgttttc
    69721 gtaatcaatg ggaaaaaact aagagtggtg tacgtaatca ataaaaagga tggtgacaac
    69781 agtacctctt tactctctga aagcatcata actcgttttt cctcattatg ccaataaatt
    69841 gttgttatac cacatataag gatttgtaat agctaaaaac agacaggaaa gttgaaatct
    69901 gtgaatctta ttttgtatgg aaggatttat agaacgcaaa aatcaagata aagatgaata
    69961 aaaatcctgt ttcggctata tattgcgtat ctacgccaat aaaacgagtt tgttctgtca
    70021 tagccatata aagcaaaggc aaaaatacaa ctacagcgag ataagatccg atgatttctc
    70081 gaaaagtttt ccaggaagta tgtttcctgt ttttatattt atccgatttc attgaatagt
    70141 catagcctcc ttattctttc atatgttgaa attccagtat aaaaactgga aggaactgta
    70201 cgttttttag aataaaaatt ataagggata agtaggctgc tgtctataat aagatatatt
    70261 tttcaattct ttattaaaga ttttattgac aaaatgaatc cgttttctat gatggaggag
    70321 gggtgaataa gttgttgaag aaggaaattt tatgttactt agagaaccag acagcctttt
    70381 tcgatttaga acatatgaac gaggtcttta cagcacaaag gttagctgat cattttgggg
    70441 taaaaagaaa cacagtcagt cattatttga accagttaaa tgatgagcaa ctactagtca
    70501 aaatcaattc tcgaccagtg atttatttcc acaaagaagc ttttgaaaaa caatttttta
    70561 agttacgcac gaatttttat ttttctatcg atgatctcaa agaggaacag ccttttttcg
    70621 cgcaaccaaa agacttattc tcttttatga tcggatacga cgccagtttg aaagaaagta
    70681 tcgaacaaat caaaacagct ctttactatc cagatggcgg attaccactt ttgattacag
    70741 gcgaaagtgg cacaggtaaa agttatttag ttaatttggt ctatcagtat tgtctgcttc
    70801 atgatctgct agaagattct gcaccattca tcacttttaa ttgtgcacaa tatgcagata
    70861 atcctgaact tttgactagc aatttgtttg gacatgttaa gggagcgtac actggtgcag
    70921 aagaaaataa aaaaggggct tttgaagcag cagatggtgg gatcttgttt ttagacgagg
    70981 tacatcgctt aacaccagaa ggtcaggaaa aactgttcac ctatcttgat caaggtgtga
    71041 tttatcgtat gggagaacct aatttgtcac gccggatcaa aacacgtctc ttttttgcta
    71101 cgactgaaga gattactagt catttcttaa caactttcat tcgaagaata cctatccgaa
    71161 tcgaactacc tgcacttaat cagcgtagtc gtaatgaacg gctagaactg atttactctt
    71221 tttttctcga agaacaaaga aaaatgggga gccctttgtc agtcagtgga ccagctttgt
    71281 cacttttaac aagtcagaaa ttatccggaa acataggaga gctgaaaaat atcgtcaaag
    71341 tttcagcagc aaaagcatat gctgaacagc gtgaacagcc tgaaatccat gtcacgatcc
    71401 atcatttgca aaaagaacta cttgcgcagc ctattactaa aaatacagca cagcaaggaa
    71461 tctatattac gcaagaccag accttagagc aattaatgga gaagcaacag cccgaacagc
    71521 agcgaatcgt taaaagtttt gagcaaatcc taattgattt caagaaaaat aactgtctgc
    71581 tatattcttg cgaaggaaaa ttaaagcaag aagtgattca attatttgat tttttgctgt
    71641 ttgagaccag tagacaagaa aaacacgagc tgctggttta ttggacacaa tctatccgag
    71701 agacctttcg acaaatggaa actgcctatc aaatcaaatt cgatggaaac agtgtctatg
    71761 ccttgagtta ctatctctat cagcgaagca ctatcaaatg gttaccggaa gaacatgata
    71821 ttatccaact aatcaaagaa ttagaacaac aagtttctca gtcttatcca tctagttatc
    71881 actatgtcca acgaattctg gaattaagta agatcaaatt agatattgaa gacacaagta
    71941 tggatcggat tttactgacg atctatctaa aaaaagcgaa atggtcaaaa gaaaaacgac
    72001 tgccaaaagc gatgattgct gctcacggtt atgcaactgc tagcagtatg gcaaatgtag
    72061 taaatcgttt attacaagag gatctatttg aatcatttga tatgccacta gatgtcacac
    72121 cacagcagat tgcttcagaa atccttgatt attgcgaaaa cagcgatgtt tcaaatggat
    72181 tgatcatatt agtagacatg ggatctctga aagaaatcca tcagtttttt aaaaaacagt
    72241 tatccgtacc gcttttgatt ttgaataatg tgacgacacc tttagcaatc acagtagggg
    72301 aatgcctgca aaaaaatgta tcattagaag agatagcaga agagactgtt cgacagatcc
    72361 agccagaatg gcgactgctc tatccagagg aaaacaaacc caaagcactc attactactt
    72421 gcttcactgg aatcggtacg gcggtccact taagtgaact gctagaaaaa agcttaccta
    72481 cggcttgtca gttgaaaatc atcccatatg aatatcagca attaaaagat aagaaaaaca
    72541 gtgacccatt attttccata tacgaagtcg taggaatgat tggcaccaca gatcctgata
    72601 tcaccaatat cgactatctt tcattagaag acctcatctc gggggaaaag atgtctgtac
    72661 tagctgaatg gttggacact actatgaatg cttcagagaa ggaaatattc aatcagcgca
    72721 tcattcgtaa tttttcattg gaaaaagtac tggattccgt gactattcta gatacagaga
    72781 aggtgatggg agaaatcgat cattttatga gagaattaga ggtgcagttg aatcgaagca
    72841 tcagcaatcc caaaaaatta gcgttgtatg tccatgtgag ctgtctcatt gaacgattga
    72901 tccgacaaat gccaatcgaa acctatcaag gattagagaa atggaagcag tgtcaaaaag
    72961 aagggttatc tgctattaaa tctgcgttta gtgtcattga agagcattat agtgtcatga
    73021 tccccaattc tgagattgcc tatatctatg atattttgag tgaagataca gagtttctct
    73081 cgatagaaga agaattttga acataagcaa gttgttgcca ctaattttgg catgcaactt
    73141 gcttttttag tatgtgtaag tgaaaagagg agatgaaaaa gtggatagag aaattatctt
    73201 agcttcccat ggaaaatttg cttcagggat attagattca ttagagctga tctatgggaa
    73261 aaatcattct attactgtat tcgattgcta tactgatgag aattttgatt tagcggaaac
    73321 agtaaggcag ctttttatga ggtacaaaga taaagaaatc attgttctga cggatctttt
    73381 tggcggaagt gtcaacaacg aattcttaca atatatcaat cgggatcatg tctatctcgt
    73441 tgccggattg aatttgccac tattgattga gctagtatct cggttggacg ctgaagtaga
    73501 gacaactgtt ttgatccagc aggtgctaac tgattcaaaa aaaatgatcc agttttgtaa
    73561 cgagcggctc aatcagaaaa tagaagaaga cgaattttag gaggaagaaa aatgattgta
    73621 ttgacaagag tcgaccatcg gttattacac ggacaagtag ctttttcatg gacacaaaca
    73681 ataggcgcag actgtatttt gattgctaat gatgatgtac ctacgaatga gatacgaaag
    73741 acaacgatca aattagccaa gccacaagga gtcaaactag tgatcaaatc aattgatgac
    73801 tcgattgccg cgttgaaaag cggggtgaca gataaatata agttattcat cgtagtggaa
    73861 tcgatcgagg atgcatataa gctggcagaa gcgtatccag aaatcaaaac catcaactta
    73921 ggagggatca aggcaaaacc tggtactcgc agcatcggaa aagcggtaaa tattttacca
    73981 gaagaggagg aacgcttgaa acgattaatt gacaaacaaa tagaagtaga aatccgtcaa
    74041 gtaccagcag ataaaaaagt ggatgtaaga gaagttttgt aagaaaggaa gaacctcaat
    74101 gattgtacaa gcagtcttat taggaattgt tgcatttgtc gcacaatcag aatatgcact
    74161 agggacatcg ttgctttctc gtccgattgt gacggggctg tttacaggaa tcgtgttagg
    74221 tgatgtaaaa actgggatca ttatgggcgc aactttagag ttagcattta tcggatcgtt
    74281 ctcagtaggt gcttcgattc cacctgatgt tgtgaccggt gggattttag ggacggcttt
    74341 tgctattaca gctggagccg gtacagaaac cgcgctttta ctaggtttgc cgattgctac
    74401 gttgacattg atattgaaaa atatttactt agggcttttg attccaatta tgaaccataa
    74461 agcagacaat tatgcagaag aaggaaatta taaaggagtc gagcatatgc acttgcttgc
    74521 cggtatcggt ctttccttga tgcttggtgt tgtggtaatg gtttcttata tggtgggaag
    74581 caatacgatc ggaaatctat taaatatgat tcctgacttc gttcaaaagg ggttgtcagt
    74641 agctacaggg ttgattccag ctcttggttt tgcgatgctt gctcgtttgc tgatcaacaa
    74701 acaagttgca ccatattttt tcttaggttt tgctatagct tcttacttag agattcctgt
    74761 gaccggagta gctatttttg gtgcgatttt agcagttgtg gtagtcaata ttatgaatgt
    74821 ccgtcaacta ccacttcaaa caactgcagg ggaggtagaa gaagatgaag aattctgaga
    74881 tcaaaaacag caaaataacg aaaaaagagc taaatcacgt attttggcgt tcttttcaaa
    74941 tggagttttc ttggaattat gaacgtcaga tgaatatggc ttatgtttat gcaatgattc
    75001 cgattttgaa aaagttatat cagtcgaaag aagaaatggc agcagctttg aaacggcatc
    75061 tagagttttt taacacgacc ccacatatcg ttacactgat tttaggaatc acggctgcaa
    75121 tggaggaaga aaataaggat gatcctgaat ttgatgtgac tgcgatcgat agtatcaaaa
    75181 catctttgat gggacctctt gcagggttag gagattcttt cttttgggga actttgcgat
    75241 tgattgccac aggtgtgggt acctctttag ccatgcaagg aaatatttta ggccctatct
    75301 tgttcatttt gattttcaat attccgcaca ttctgtttcg ctatctagca acaggttggg
    75361 gatatcgctt aggaacgggt tttttgaaaa agatccaggc aaacggtatg atggaaagtt
    75421 tgacattagg cgcgtctatt attggactga tggtcgttgg agcaatgact gccacgatga
    75481 tcaccatcaa tattccttta aaaatcggtt caggagaaaa tgctgtgact gttcaaagta
    75541 tttttgatga tatcgttcca aatatcttat gtcttggagc atttggcata gtgttttatc
    75601 tattgaagaa agaagtgaaa ccattaacga tcttgatcgg actagctttc tttggaattt
    75661 ttggttcgtg gatagggatt ttttaaaaaa ggagcagaga aaatgtttac gatgcaagat
    75721 tatatctatg aagaaaagga agtactaagt acgatcttga aaaagaatga tttttcgaca
    75781 agagaacata tgaaaaaaac agtgaattta ctgatcttag caacgggttc atcttataac
    75841 gcttgtttag cagcgaagcc agcattggaa tcttatggtg atcttactgt cgatattcaa
    75901 gaaccttttt attttttcaa ttatggaaaa ctttctcctt caatcgatac tgtgattgct
    75961 gtgtcacaaa gcgggaaaag tgcttctact gttgaagcag taaaaatgat acaaaaacaa
    76021 gggttacctg ttgttgctat cacaaatgac gtgcaaagtc cacttgcttt agaagctgca
    76081 caaattattg atttaggtgc cggggtagaa tcagtaggct tcgttacaaa aggctattct
    76141 gcgactgttt tacagttact actcttaggg ataggaattg gaataagtaa aaataaaatc
    76201 agcaaaaaaa tagaacaaga ctacatgcaa cagttgcgca aaataatcaa ccatttacca
    76261 gcgattattc aaaaaacgga agaatttttt gatggatatc aaagtttatt tcgtttagca
    76321 cagcgtttcg tcaccattgg atatggtcca aactggggaa cagctaaaga agcagagacg
    76381 aaattgactg aaacaatccg cgttccgtca caaggatttg agttagaagc ttatatgcac
    76441 ggcccatacc tggaggcaga tgcttcgcat ttgctattct ttattgaagg ggaaagtgta
    76501 aataaggaac gttcgcaaaa gttgcaaaga tatatgagtc ggtacgttgg agagactctc
    76561 accattacca caaaaaaagc aagaaacgag aaaacacttg gattagcaat agaatgtgat
    76621 gaatatctgt ctgtattagc gcttgtcgtt ccgtttcaac tattcgctta taaaaccgca
    76681 gtagctaaag gtattgactt gaacaaaaag atttttgaag actttgatac agtcttgaaa
    76741 agtaaattat aagaggtgga aatcatgctg aaattcaatg aagaagaaca aatcaaagca
    76801 ataaaaggcg cactagcttt acgtccgcaa gtagaagaaa tcatcgataa actttatgcg
    76861 gaaaaatttg acgctgtcta ttatctagga atcggtggaa cgtatgcttc ctcgatgcaa
    76921 gctgtcactt atatgaatgg gaaaagcaac ttgcctgtct ttgtacagca tgctgcagaa
    76981 tattacacta ctggaaacaa aagattaaca aaagattcta tcgttatttt gtcctctgtt
    77041 accggtacaa ctcaagaagt agtgaaagca gtagaacaaa tcaagaaagt aggagcgaca
    77101 ctgattggat ttatcgataa agcgaacagt aagttgtctc agctatgcga ttttgtggtc
    77161 acttatccag ctcctggaac agaacaaatc aaatttttta tggcagcaga tcgattgatg
    77221 tatttgaatg gagaattcga agcttattca gaatactatg aacagctcga acgttattta
    77281 ccaacagggt tagtggaagc agagaaaaaa gcagatgcat ttggcttatc atttgcagaa
    77341 aaacatcgac gtgatagtat gcattatttt attggagcag ggaatcaatg gggagctgtt
    77401 tattcatatg ccatgtgtta ctgggaagaa caaagctggc ttccatcgaa atctatccat
    77461 gctgccgagt ttcttcacgg gacgttagag atcgtagaag aaacaacccc agtcacatta
    77521 tttttaggcg aagatgaaca gagagtgtta tctgaacgtg tggctaaact tttgccaaaa
    77581 atttgcagca attatacatt gatagacaca aaagactatc cagtagaagg tatcagtgaa
    77641 aaatatcgcg gacgtgtttt gtctttctta ttgatgcatg tagtgacaca acgcatcgat
    77701 gctcatgtgg agcagttgaa ctgccatcca ttagagatac gccgctacta tcgtcagttt
    77761 gattattagg atagactgga taaaaagaat ataaaaaata aagagagcag cgataactgc
    77821 tccctttatt tttttaaaat attggcatca attacgttat aaaacacatt ttttgcatta
    77881 tctacagttc aacttataat ctgtttaatg ggacatgtgg gtgccaacca ttttttgtta
    77941 tgcaatagta ctatttagtt gttgcatgga tccgtagtaa aagtccaagt acaacgagtt
    78001 gcgccagttt acatagcgtt ttgtatccag aatgttgact aaaacaaaag ttcctatgtc
    78061 aaccgtcaac agagacaatc tgtccgttgc aggacctgac agatttagaa atgttcaatc
    78121 tgtctcttat gtattttaaa tcaatactca ctaggagaag tttcctaacc tcctaatagt
    78181 aatgctggta gtaacattgt caaaactgct tcctcttagg aacaagcaaa gcataacgag
    78241 tgtaaaaata aaatgtagac tattgtaaca tatcattgat tatttcaagt aaaaacgata
    78301 aaagaagtaa acaaacactt aaaaacaatg gaaattagtc ccaactttaa gaaatgtata
    78361 ctataatgga aattatcaat tatttatttg gaggaatatc catgaaacaa aaaatcgcag
    78421 ttcttggtcc tggatcttgg ggcactgctt tagcacaaac attggcagaa aacgggcatg
    78481 atgtccgtat ttggggaaat gtacctgaac agattgatga aatcaataag tatcatacaa
    78541 atcagcattt tttacctgat ttgacgatcc cagaatcgat tatcggatat aaagaattgg
    78601 cagaagcagt ggataacgca gatgctattt tatttgttgt tccaacaaaa gcgattcgtt
    78661 cagtcgcaca ggaacttatt ggtaaaatga atactaagcc aatcattata catgcaagta
    78721 aaggactaga acaagatacg cataaacgaa tctcagaagt tttggctgaa gaaattccag
    78781 aagaaaaaag acaggcaatt gttgtattat ctggtcctag ccatgctgag gaagtggcag
    78841 tacatgatat cacaacaatt acagctgcaa gtattgatca aaaagcagca gcctatgtac
    78901 aaaaactgtt catgaatgat tatttcagga tttatacaaa taatgatgtg attggcgtag
    78961 aaactggtgc agcactgaaa aatatcattg caattggtgc cggcgctatc catggattag
    79021 gattcggaga tgatgcaaaa gcagcaatca tgactcgagg attggcagaa atcagccgtc
    79081 ttggtgtcgc gatgggtgcc aatcctctga catttatcgg tttgagtggt gtgggggact
    79141 tgatcgttac ttgtacaagt gttcattctc gcaattggcg tgccggtaac ttgttaggac
    79201 agggacataa gctggaagaa gttctagaaa acatgggaat ggtcgttgag ggtgtggcaa
    79261 cgacaaaagc agcagtagag ctagctcaac agctaggtgt tgagatgcca attactcaaa
    79321 caatctataa tgttttgtat aatggagaag atatcaaaaa agcagcaaaa gaaatcatgt
    79381 tacgtgacgg aaaaatggag aatgaatttt ctcttcgtta aatagatgat caatagttaa
    79441 tc
//
LOCUS       DBBGSZ010000010        72789 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.010, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000010 DBBGSZ010000000
VERSION     DBBGSZ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 72789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72789
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.010"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(19..729)
                     /locus_tag="ACIZE5_000956"
     CDS             complement(19..729)
                     /locus_tag="ACIZE5_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HGC6108116.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(726..2198)
                     /locus_tag="ACIZE5_000957"
     CDS             complement(726..2198)
                     /locus_tag="ACIZE5_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HGC6108117.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            2336..2809
                     /locus_tag="ACIZE5_000958"
     CDS             2336..2809
                     /locus_tag="ACIZE5_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGC6108118.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(2962..3513)
                     /locus_tag="ACIZE5_000959"
     CDS             complement(2962..3513)
                     /locus_tag="ACIZE5_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGC6108119.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            3618..4148
                     /locus_tag="ACIZE5_000960"
     CDS             3618..4148
                     /locus_tag="ACIZE5_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HGC6108120.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(4631..5074)
                     /locus_tag="ACIZE5_000961"
     CDS             complement(4631..5074)
                     /locus_tag="ACIZE5_000961"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6108121.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(5090..6250)
                     /locus_tag="ACIZE5_000962"
     CDS             complement(5090..6250)
                     /locus_tag="ACIZE5_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HGC6108122.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            6757..8457
                     /locus_tag="ACIZE5_000963"
     CDS             6757..8457
                     /locus_tag="ACIZE5_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108123.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(8559..9392)
                     /locus_tag="ACIZE5_000964"
     CDS             complement(8559..9392)
                     /locus_tag="ACIZE5_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGC6108124.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(9696..11861)
                     /locus_tag="ACIZE5_000965"
     CDS             complement(9696..11861)
                     /locus_tag="ACIZE5_000965"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HGC6108125.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            12121..14415
                     /locus_tag="ACIZE5_000966"
     CDS             12121..14415
                     /locus_tag="ACIZE5_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HGC6108126.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            14408..15073
                     /gene="pgmB"
                     /locus_tag="ACIZE5_000967"
     CDS             14408..15073
                     /gene="pgmB"
                     /locus_tag="ACIZE5_000967"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HGC6108127.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            15066..16073
                     /locus_tag="ACIZE5_000968"
     CDS             15066..16073
                     /locus_tag="ACIZE5_000968"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGC6108128.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            16095..17114
                     /locus_tag="ACIZE5_000969"
     CDS             16095..17114
                     /locus_tag="ACIZE5_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6108129.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(17395..18762)
                     /gene="nhaC"
                     /locus_tag="ACIZE5_000970"
     CDS             complement(17395..18762)
                     /gene="nhaC"
                     /locus_tag="ACIZE5_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HGC6108130.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(18871..20292)
                     /gene="tyrP"
                     /locus_tag="ACIZE5_000971"
     CDS             complement(18871..20292)
                     /gene="tyrP"
                     /locus_tag="ACIZE5_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070908 - tyrosine:tyramine antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-tyramine antiporter"
                     /protein_id="HGC6108131.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(20535..22412)
                     /gene="tdc"
                     /locus_tag="ACIZE5_000972"
     CDS             complement(20535..22412)
                     /gene="tdc"
                     /locus_tag="ACIZE5_000972"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HGC6108132.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(22703..23959)
                     /gene="tyrS"
                     /locus_tag="ACIZE5_000973"
     CDS             complement(22703..23959)
                     /gene="tyrS"
                     /locus_tag="ACIZE5_000973"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HGC6108133.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(24071..24276)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            24539..25840
                     /locus_tag="ACIZE5_000974"
     CDS             24539..25840
                     /locus_tag="ACIZE5_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HGC6108134.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(25909..26508)
                     /locus_tag="ACIZE5_000975"
     CDS             complement(25909..26508)
                     /locus_tag="ACIZE5_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6108135.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            26762..27643
                     /locus_tag="ACIZE5_000976"
     CDS             26762..27643
                     /locus_tag="ACIZE5_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGC6108136.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            27656..29266
                     /locus_tag="ACIZE5_000977"
     CDS             27656..29266
                     /locus_tag="ACIZE5_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6108137.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(29343..30002)
                     /locus_tag="ACIZE5_000978"
     CDS             complement(29343..30002)
                     /locus_tag="ACIZE5_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HGC6108138.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(30285..30950)
                     /locus_tag="ACIZE5_000979"
     CDS             complement(30285..30950)
                     /locus_tag="ACIZE5_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HGC6108139.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(31097..31702)
                     /gene="dhaL"
                     /locus_tag="ACIZE5_000980"
     CDS             complement(31097..31702)
                     /gene="dhaL"
                     /locus_tag="ACIZE5_000980"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HGC6108140.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(31730..32740)
                     /gene="dhaK"
                     /locus_tag="ACIZE5_000981"
     CDS             complement(31730..32740)
                     /gene="dhaK"
                     /locus_tag="ACIZE5_000981"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HGC6108141.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(32715..33110)
                     /gene="dhaM"
                     /locus_tag="ACIZE5_000982"
     CDS             complement(32715..33110)
                     /gene="dhaM"
                     /locus_tag="ACIZE5_000982"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HGC6108142.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            33264..33584
                     /locus_tag="ACIZE5_000983"
     CDS             33264..33584
                     /locus_tag="ACIZE5_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HGC6108143.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(33696..34553)
                     /locus_tag="ACIZE5_000984"
     CDS             complement(33696..34553)
                     /locus_tag="ACIZE5_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGC6108144.1"
                     /translation="MKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTISSSG
                     AENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELEEALE
                     AAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQQAKE
                     FNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAASFQRI
                     KDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGVLVAA
                     AYGIIRKKK"
     gene            complement(34661..35965)
                     /locus_tag="ACIZE5_000985"
     CDS             complement(34661..35965)
                     /locus_tag="ACIZE5_000985"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGC6108145.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(35962..36471)
                     /locus_tag="ACIZE5_000986"
     CDS             complement(35962..36471)
                     /locus_tag="ACIZE5_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108146.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(36646..38781)
                     /locus_tag="ACIZE5_000987"
     CDS             complement(36646..38781)
                     /locus_tag="ACIZE5_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HGC6108147.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(38864..40519)
                     /locus_tag="ACIZE5_000988"
     CDS             complement(38864..40519)
                     /locus_tag="ACIZE5_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGC6108148.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(40521..40835)
                     /locus_tag="ACIZE5_000989"
     CDS             complement(40521..40835)
                     /locus_tag="ACIZE5_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGC6108149.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            41005..41265
                     /locus_tag="ACIZE5_000990"
     CDS             41005..41265
                     /locus_tag="ACIZE5_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HGC6108150.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            41279..41593
                     /locus_tag="ACIZE5_000991"
     CDS             41279..41593
                     /locus_tag="ACIZE5_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HGC6108151.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(42323..42877)
                     /locus_tag="ACIZE5_000992"
     CDS             complement(42323..42877)
                     /locus_tag="ACIZE5_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HGC6108152.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(43003..44932)
                     /locus_tag="ACIZE5_000993"
                     /pseudo
     CDS             complement(43003..44932)
                     /locus_tag="ACIZE5_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(45238..45954)
                     /locus_tag="ACIZE5_000994"
     CDS             complement(45238..45954)
                     /locus_tag="ACIZE5_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGC6108153.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(45955..47778)
                     /gene="glpO"
                     /locus_tag="ACIZE5_000995"
     CDS             complement(45955..47778)
                     /gene="glpO"
                     /locus_tag="ACIZE5_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HGC6108154.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(47792..49288)
                     /gene="glpK"
                     /locus_tag="ACIZE5_000996"
     CDS             complement(47792..49288)
                     /gene="glpK"
                     /locus_tag="ACIZE5_000996"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HGC6108155.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(49424..50884)
                     /locus_tag="ACIZE5_000997"
     CDS             complement(49424..50884)
                     /locus_tag="ACIZE5_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6108156.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(50874..52169)
                     /locus_tag="ACIZE5_000998"
     CDS             complement(50874..52169)
                     /locus_tag="ACIZE5_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGC6108157.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(52501..53178)
                     /locus_tag="ACIZE5_000999"
     CDS             complement(52501..53178)
                     /locus_tag="ACIZE5_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HGC6108158.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(53208..54299)
                     /locus_tag="ACIZE5_001000"
     CDS             complement(53208..54299)
                     /locus_tag="ACIZE5_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HGC6108159.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEKAYKELYLPSPLYNFLKARYQ"
     gene            complement(54400..54834)
                     /locus_tag="ACIZE5_001001"
     CDS             complement(54400..54834)
                     /locus_tag="ACIZE5_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGC6108160.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(55418..56875)
                     /locus_tag="ACIZE5_001002"
     CDS             complement(55418..56875)
                     /locus_tag="ACIZE5_001002"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC6108161.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(56872..58767)
                     /locus_tag="ACIZE5_001003"
     CDS             complement(56872..58767)
                     /locus_tag="ACIZE5_001003"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGC6108162.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(58825..60600)
                     /locus_tag="ACIZE5_001004"
     CDS             complement(58825..60600)
                     /locus_tag="ACIZE5_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HGC6108163.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(60650..62146)
                     /locus_tag="ACIZE5_001005"
     CDS             complement(60650..62146)
                     /locus_tag="ACIZE5_001005"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC6108164.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(62340..63962)
                     /locus_tag="ACIZE5_001006"
     CDS             complement(62340..63962)
                     /locus_tag="ACIZE5_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HGC6108165.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(64290..65603)
                     /locus_tag="ACIZE5_001007"
     CDS             complement(64290..65603)
                     /locus_tag="ACIZE5_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGC6108166.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(65848..66072)
                     /locus_tag="ACIZE5_001008"
     CDS             complement(65848..66072)
                     /locus_tag="ACIZE5_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108167.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(66092..66514)
                     /locus_tag="ACIZE5_001009"
     CDS             complement(66092..66514)
                     /locus_tag="ACIZE5_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC6108168.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(66656..67366)
                     /locus_tag="ACIZE5_001010"
     CDS             complement(66656..67366)
                     /locus_tag="ACIZE5_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HGC6108169.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(67384..67881)
                     /locus_tag="ACIZE5_001011"
     CDS             complement(67384..67881)
                     /locus_tag="ACIZE5_001011"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6108170.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(67918..68370)
                     /locus_tag="ACIZE5_001012"
     CDS             complement(67918..68370)
                     /locus_tag="ACIZE5_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGC6108171.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(68505..69110)
                     /locus_tag="ACIZE5_001013"
     CDS             complement(68505..69110)
                     /locus_tag="ACIZE5_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGC6108172.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(69560..70180)
                     /locus_tag="ACIZE5_001014"
     CDS             complement(69560..70180)
                     /locus_tag="ACIZE5_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC6108173.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(70182..71051)
                     /locus_tag="ACIZE5_001015"
     CDS             complement(70182..71051)
                     /locus_tag="ACIZE5_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HGC6108174.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(71074..71481)
                     /locus_tag="ACIZE5_001016"
     CDS             complement(71074..71481)
                     /locus_tag="ACIZE5_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGC6108175.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(71500..72789)
                     /locus_tag="ACIZE5_001017"
     CDS             complement(71500..72789)
                     /locus_tag="ACIZE5_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGC6108176.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
BASE COUNT        21056 a        15323 c        12664 g        23746 t
ORIGIN      
        1 tacatggtgt tcaaaatatt attcgccttt tgcttctttc actaattttg cgaatgcttg
       61 ttgttggaat tcagcagcta aggctttcgt acgttgttct tgctctgctt tgctcatttt
      121 tggattttca gtcattgctt ttaccatacc gtcttgaaca taagcttttg cttcactttc
      181 catcgtactt tgctgtttct tcactaattc agctaacttg gctgcttggt ccgtacttaa
      241 ttctacccat gtctctggga ttttgaatgt attcactcgg ctgtcatatt cgtgattgtt
      301 atcagcaata ttgaaccaga atttatacat gtcgtttttg tattcccaat aagtagtttt
      361 cgtcactttt tcagcatcgc cgtctgtctt ttctacttta tttgtttcgt tatccgtacc
      421 agttgctttt ggtttttctt gtttttcatt tgttcggtaa agatacactt tttcttttcc
      481 attccctaaa gctttataca aaagcatatc tgctccttgg gaatcagcac tggaaacaat
      541 tttttctgtt tttgtttccg ttactttttc cattccaaag tgattggaca aattagcgac
      601 gatcaaactt agtgaagcga cgaagattag tccgaaaatc aaagataaaa aggtttgcca
      661 tgttttttta gcgaacacgt tcgttaaagc aaaagcaagc aagctgacaa tcaaaactcc
      721 aataatcatg cattatcccc cgctttcatt agaacaggtt cttttttctt caataaaaag
      781 gcaataataa agccaagaat cccaaagatg atcgctacga taaacgcggc atggtaacct
      841 gacagtgtgg cattgattgc ctgatcttta taagctaatg gcgtattatc caatacagat
      901 ttgcttggga tatttgcttt tgtcacattc gtcaacacac tgatcaaaat agctgtacca
      961 atcgagcttg cgatttgacg gaatgtatta tttaccgctg tcccatgact gatcaagtta
     1021 tttggcaatg cattcatacc agaagtcgtt accggcatca tgaccatgga gatcccaaac
     1081 atacggatcg cataaaggat cacgatatat aaaactggag tcgtttttgt caagaaagca
     1141 aatggtgcag ttgccgctgt caaaatgaac atccctgtga tggctaaacg tttcgcgccg
     1201 tatttatcga aaatcgcacc cgtcacaggc atcatagccc ccatgatcaa tgcacccggc
     1261 aacaacatca agccagaatg gaatgctgat tctccacgaa tattttgaat atacaatggt
     1321 acgaccattt ctgcccctac catcgccata tttgttacac cagctaaaac agctgcaatc
     1381 gtgaatgtag atgatttgaa tacacgaagt tccaagaatg gatgttccaa atgtaattga
     1441 cgccatgaga acaaggcgat gaaaatcaca ccaacaacta agaaaccaat tactttcaag
     1501 cttccccagc cgtcatctcc tacactagaa aatccgtaaa gtaaactacc gaatccaatc
     1561 gttgataaaa tagcggataa aatatcaatg ctaggatttg acaatggaat aacacttttc
     1621 attaggaaga atgctaaaac caagacaaga acaacgattg gcagtaccat accaaacaag
     1681 tcacgccaat ggtagttatc aatgatataa ccagataatg tagggcctaa agcaggagca
     1741 agtccaataa cgatccctga catccccatt gctgatcctc ttttttctgg cgggaaaata
     1801 gatagcatga tattttgcaa taatggcatc gatactccca caccgcaagc ttggatcaaa
     1861 cgaccgatta gtaatgtact aaaattaggt gctgtaaagc aagtaatcgt tccgatcaaa
     1921 aagatcgtca tggcagaaag atataaattt cttgaactga atttattgat cagccatgct
     1981 gttattggga tcatgatccc gttgactagc aagaaaccag tcgttaacca ttgcacatca
     2041 gacgctgaaa tatcgaaagc tttcatcaat gtaggaaaag ctgtcgtcaa taaggtctga
     2101 ttcaaaacgg tacaaaatgt accaattaat aagacaacaa ctaaaagtgt ccgattatat
     2161 ggttttccgt aaatatctac gggttggttg ttactcatat ttctccttct ttctgaattt
     2221 tttctgaaac tactagaata ctttagtcct aaattcgcta tttgtcaacc tacttgacac
     2281 ataagttaat acggatataa ttaagggaag caagaggaca aaaggagtga caaaaatggt
     2341 tggggcttcc cttaaacgtt tgttggaaaa tgatcaattg gttgttggca tcagtgaatt
     2401 aagtgatatc gtaggtgtgt ctccacgtca attaaggtat tgggaacaaa agggattcat
     2461 tcgttcgatc gaagctgatg cgaattgtcc tagaaaatat cgtttaccta cagtcataaa
     2521 agtagaactg atcaaaaaat atttagatga cggatttact ttgtcaaaag ctgcagaaaa
     2581 ggcagaaatc cgccaaaaga aaatgcacca tgtccgtaaa gttttttcaa aagcaatcaa
     2641 agatatcgaa ttgatcgacg aacgctatac gattttacaa atcggtaact tcaaagaaga
     2701 gaatgctaag atgtacatca ttcatgacaa cgagacagac gaattaactt acaagctcct
     2761 tcctgtcgat gaaaaagctg actacgaaca gttgttaaaa gaactctaaa cgccactaat
     2821 ctcctaagta ccaagctttt taataagtag atgctacata aatacttgaa aaaaggcctg
     2881 tttgaacata agaatatccg aacggtgatc tgcgtttctt tcatatagaa aggaattctc
     2941 catcactgtt cggatatttt tttatttttt tcggttactt tcttctaata catctgttag
     3001 ccaatttgca tattctgttt cccgattgat cgcatgcgct aaaatcaggt agtgtccgta
     3061 attttcatgt ttttcttttt cagtaggaaa gatcgttttt tttcgctcta atagatgaag
     3121 tcgtttttct tcatgaaggt cacgctgctg ctgaataatt tctactaatg ccggatcatt
     3181 cacgtctttg acgaaataca atttcagaac aaattcgtct cgattaaccg gtagttcatt
     3241 ggtgggtgta tgaatccact ctgccaattg ttccttccct tcttctgtta attcataaac
     3301 tttcttttcc aatttttcac ctgtgatctc tacttgatgc tgaatgattc cttgctcttc
     3361 catttttgca agttcaggat aaatctgact atgttttgct tgccaaaatt ctcctatttc
     3421 atttttgaac gattgattca attcatatcc tgtcatcttc ttcttactta ataaccctaa
     3481 caaaatatat cgaagtgtat tttttcttgc catcagtttt ccctccttga caaatcttta
     3541 aatccattct atcataaatg agtaatcgaa aacatgtagt ttattacatg ttttaattta
     3601 taaggagatg cttaaacatg aaagaattta aagaattgga agattttatt ggaactcact
     3661 ttatctatac gtatgacaat ggttgggaat atgaatggta tgccaaaaat gaccatactg
     3721 ttgattaccg tatccatggc ggaatggtca aaggccgttg ggtaaaagac caagaagctg
     3781 atatcgttaa attgacggac ggcgtattca aaatcacttg gacagagcca acagggacag
     3841 acgtggcatt ggactttatg ccaaatgaaa agaaacttca cggaatgatc tttttcccta
     3901 aatgggttga agaacatcca gaaatcactg ttactttcca aaacgaacat atcgcagaaa
     3961 tggaagcagc tcgtgaaaaa tatgaaactt atccaaaatt acttgttcct gaatttgcta
     4021 cgatcactta tatgggtgat gcaggtatag acaatgaaga tgttattagc gaagaaccat
     4081 acgatggaat gccagatgat atccgtagcg gaaaatactt cgatgaaaat tataaacgag
     4141 taaaataagg ttgtgaaaga gaggttgtga aatcagcgtt ctgacctgag tattagagaa
     4201 agaaacggaa aaatagttcc tcatgttttg ccgttttttg agctaatacc gagggtcagc
     4261 tgattgaaca ccgtttatca agaggttgtg aaatcagcgt tatgctttga gtaataagaa
     4321 cgctagttag aaaatagctt ttcatatttt ctaggctagt gggcttatta ccgagaagca
     4381 gccgtttgaa caccgtttat caagaggttg tgaaatcagc gttttgacct gagtattaga
     4441 gaaacaaatg gaaaaatagt tcctcatatt ttgccgtttt ttgagctaat accgagggtc
     4501 agctgattga acaccgttta tcaaagattg taacaactgc atattcacac agttaaatta
     4561 gtgacttcaa aatgaaataa tgctcccagc aaaaaattag gctgggagca ttatttcgtt
     4621 attctgttca tcaaaaatca gcgttttgat tccatttcat cacaagttcc tcctcattta
     4681 ctgcttcatc tttttgctgt gtttgaattg taaaaccttg tgaaagatag aaatgaatag
     4741 ctgattgatt tttttgatag actgtcaaag tcagtgtttt attggtttct tttatttttt
     4801 tcattagttg cgtaccgatt ctttgttgcc ggtattccct tttcacaaag attcctgcga
     4861 taaactgatc aatcacccca gcaaaaccaa taatttcttg atctatttct gctaagtaaa
     4921 tcactgcatc tggtaaagct ttcctaacag attctacttg attctcccaa taagttgatg
     4981 gaatgaattc atgagaatcc aagttagcat gcagccaaat cgatagaaca gattccagtt
     5041 ctttggcaga caattttgtt gttgtgcgga tcattttttc tctccttact tattcattga
     5101 ttttaaaata aaaaccattt ttttgaagct cttttacaag ttttcgcccc tcaaaaaagt
     5161 atatcttctc ttgttttact tttctaatac caaaagaaac agcaacttta ggatcatcag
     5221 ctgaaacgat tcgataagtt ccaccaggca attgatccag cttgactttc ccatgatggt
     5281 cgctttgtac tgaaaacggc acaccatttc tagtaagtgt ttttttctta tgtttcaaaa
     5341 tgaatgaact accatttacc ggtttccctg acgaatcact aataataaat gaaaaatcaa
     5401 gcactttttt acttaatcta tactgataga ttagtcgtcc gataaacact aacagtatga
     5461 ctacagctat tatcgttcct gcaagaataa accattgccg catggttctt tcctgatttc
     5521 cttttccttc ttcttttttt accgattcgt tataaggaat ccgatgtcct gtcactagca
     5581 aacgatgcgt gttgatcata tacggcgtac atgtaagcaa ggtaactaag tcttctcctt
     5641 ctgaaatcgt tagaacagac gtgtcatctg gcagtaccac ttgtatattt ttaacttgat
     5701 aagccaattt ctcccccaaa acagtcaaaa taaacgtgtc tccgttttct aaacgatcta
     5761 attcggtaaa taaccgtcga ttaggtaaac cgctgtgagc agagatcact gaatgcgtcg
     5821 aatttccacc aagcgggaaa gaggttcctt gcaagacgcc tgctccattt tcaaggatcc
     5881 taccattgag ccgatcataa agtgaaatat ttaattggat cttaggtata ttgatacttc
     5941 cgatcagcca ttcctctaat tggctggatg ttgtactttc atttctgttc ttttcattga
     6001 aaggatcagt accaggattg aatccttggt cagttaatcg ttggtttttc tcctccattt
     6061 tctttcgctg cacttcaatt tcagctgcgg tccgtttttg tacttgttcg atacgttttt
     6121 gatcaataaa actatttaaa gaatccacat aaaatggata taaagcgatc agtaacccta
     6181 cgacgataca tattaataaa aacaaacgaa acaaaagtcg acgagactgt ttttgcttac
     6241 tctgcttcac atgtgtcctc ccttgcaagt ttttttgttc tttcttttat tatatgggtt
     6301 caggaaaaaa atagaaaatg aaagccgatg aggttgtgaa aaagctgtcc tgcatcaagt
     6361 aataagtaca gcccaaaaaa atagctactc atattttttg ttgggttggg cttattaccg
     6421 cagatgcaag cttttgaaca ccgtttaagg aagaggttgt gaaaactgcg ttatgctttg
     6481 agtaataaga gcgctagtca gaaaatagct tctcatattt tctaggctag tgagcttatt
     6541 accgagaagc agctgattga acaccgttta ccgagaggtc atgaaaaagc tactttgttt
     6601 cgagtattaa gaaaaattct gtttcaaaac aaggagatgc aacaaaactt atgtcgcatc
     6661 ctctctcctt agaactttca cttatgtttt tcttgtaaaa ttcataaata ttttcatgaa
     6721 ttttctaatt tcttgcctac ctctcgcata ggatatatga tgaatttatc taaagtttgc
     6781 aaaggagttc gacaattgaa aaaatatggc ccatttttag caattttttt cattgctttg
     6841 gcatttctca tgcctcattt attcacacat aaactaattt tgggtgctga tgccccattc
     6901 cattacaatc ggttctatga tgccgcgcaa caaattaaat atggggattt ccattatttt
     6961 ccttcccttt atggattcca gcaaagtggc aggatcgtga atgccgttta cggcccattt
     7021 ttcgcttatt tacaaggatt gatcgtgttg cttgcaggta gctggtttca ttatcagatt
     7081 ctttcaaatt tcattcttta tcttatttca ggattttcta tgctgatttt actgagatat
     7141 gtcaatgttc gaaattgggt aagtgtacca gtagccgttt tattcatgag tacgtattct
     7201 attcaatact ggtctatcaa ccaaggattc actagctggg ggacttgttt ttatccttta
     7261 tgtatgatcc ctattgctga tttcgtcctt cataaaaagt tccctgttat caaagtcgct
     7321 gtctcagtgg gacttatgac acagatccat ttactgtctt cgatcatgtt agctttgatg
     7381 tatatccctt tttatcttta ttactttttt aaccagactg aaaaaggaaa agcactgctt
     7441 caactgatta agtcggtctt gctttatttt gttctgacag caaatatttg ggcaggatta
     7501 gctattgttt acagtgggaa taagattctt cctccctttg ttaacagaga aatgagtcaa
     7561 aaggcgatag atctggatgg cagttattgg ctccattacc ctaaggcctt tcctatattg
     7621 atattatcag gttttttgct ttttattttc tttcaacaaa agaacacctt attccaaaaa
     7681 atcgtgttgt acacaagtct tgttttcttt tttctttcta ctagcttgat tccatggacg
     7741 acattgatcg aaaaaaatgt gccttttatt agtttgatcc agtttccatt tcgatttttc
     7801 gtgccattta cgctattgct tctactttac cttgcccttt cactgaacca gtggtctgaa
     7861 caaaagtggt tccgtctttt aagtatattt ggcattctta ttttttcagc acagacgatc
     7921 cagaacttat accagcatct ggaaaagtgg gaaaatgaaa catttgtcag tcgacatact
     7981 tatctattcg atacgccgga agaagcaagg aaaacattct tcagcaaaga tatgtctacc
     8041 agcttgttcg ttttccaaaa aaccacacct gactatctgc caatctataa ggagacaaaa
     8101 gacaataaat acgaccggta taacgaagaa atactagaaa acgaaacaac ttttataaaa
     8161 acacatccag gcggtctttt gacaatcaag tggaaaaaca ctggggacaa aactgttcat
     8221 atccctgtta tcgtctacga tcggactgtg ctacagcaaa atggaaaaac attgactgat
     8281 tatgaagtaa cagatatcgg gaccccaatc gtgaagcagc aaaaaggaat caacgagctc
     8341 acgcttcatt atcaaacgcc aatctatttc tatttcattc tttctcttac tttgattggc
     8401 tggtttacct tgctatgttt atttatttat catagataca agcttttacg tgcttaggca
     8461 aaagggataa atacatccga tcaaaaaact ctccaaacgg tataatcgtt tggagagttt
     8521 tattttaatc agttttttta tgttatatgt tatatttttt attcgttcac atctaattcg
     8581 atttccaccc cgtagtgatc actgatgatt ggactatcga tcccatcaaa aatccgttga
     8641 tattttttaa cctgcattcc ttcagggacg aaaataaaat ctatacgcaa tttttctgta
     8701 ttttgttccc aaccatctat tttcttttcc acagtagctg cttttccttt ttcattcgcg
     8761 acaacatacg aatcttgaag aagaaggcaa ctttctctta cagtataata accttgagag
     8821 tctactggat tattgaaatc acctaggaaa aaaagtggta cgcgagtttc caaaaagtag
     8881 ttttccaagt ttttccactc aaaataaaag ccactttttt tatctgtcca ccaagaaaag
     8941 tggcagctcg agacaaaaat gtcctgatca tctatctttg ttttcccaat caagatcttg
     9001 cgtgtctgat aatcttcttt cttttgaaat tgggagacgg taaggacctg actttccaat
     9061 gtttttttcg taagcagtgc atttccttct tcatatttat cataaccgat gtggctcatt
     9121 tcccaactcc aaaaatactc ttttccgtgt tcctttaaaa gctgaactaa acggtaggca
     9181 aaattatctt tacggatagg tacttgattc tttaccggac agaacttcat tagcttcgca
     9241 ggttctactt cttcagattc cagtaattgg ttgatttctt gtaaagcaat cacttcataa
     9301 tcttctaaca ggatcttatc tgctaattct tgcaattttt tctctggttc tggctcaagc
     9361 cagctatgcg tgttgagtgt catgaatttc attggttttc tccttgtctt catttcgaaa
     9421 caaaagggtt gtgacaaaat ttttgtcaca acctctccag caaatagtgt tctcctgcta
     9481 actcctcagt aataagctca atggaccagg agctattttt tgtttggctg tttttatcac
     9541 ttggtgcagg gcagcttttt cacgacctct ccactaaaca gtattcaaac tgctgcttct
     9601 cggtaataag cccaaccaaa cgaaaaatag gaggagctat ttttgtttgg ctgttcttat
     9661 gacttgatgc aggacagctt tttcacaacc tctccttaca ttttaatgga gccgatcact
     9721 ttaccagctg tcactgtacc taattgcttg atcactactt cttctacttt atcgtttgta
     9781 aatacgatca tgatcgttgg atctttttct tcgttttgga tcacatcaag atccatctca
     9841 gctaatttcg ttcctgttcc tacttcttgg ccttctttga cagcaatctc aaaagctggc
     9901 tgattcattt ggactgtatc gattcccata tggatcaaaa cttcgatacc atctttcgtt
     9961 tccagcccaa ttgcatgttt gctagggaaa atacttgtca cttttccagc gatcggcgca
    10021 acaacttctc ttgatgttgg aataacagca aagccgtcac ccatcatttt ttgtgagaat
    10081 accggatctt ttacttcaga taaaggaatc acttctccag aagctgcgga aactagttct
    10141 tgttctatac ctaagtattg cttactacct gcttgtccat ttcctgtaga aaccatttct
    10201 ggctctggaa tctctgctcc tgattgcagc agatcttcga tatctgattt caagacatct
    10261 gcttttggtc cataaactgc ttggactcca ttgtctttga cgatcaatcc catcgcccct
    10321 gctcgtttcc aggcttcttc agtccctact ttttctcgat catttacact tacgcgtaac
    10381 cgagtcatac aagcatcgac atctttgata ttttcttttc ctcccagcaa atgaatgatc
    10441 tggaccactt gctgatctgc tgttcctgtt ccgctgttag atacaacggt ttcttcactg
    10501 tcattgtcgt aatttccgtt acgtcccggt gtagcaaagt tgaatttttt gatcaagaaa
    10561 tttgctaaga aatacgtaac aacaccaaaa gcgatcacac acaacacgaa gttgataaga
    10621 tctccaccta gacccgcttt gatagctaac ggtgtccgag tcagcaattc gatattccca
    10681 aatgaatgga cccgcaatgg caagatatct gccatcgcaa atgcagcccc ttggatcact
    10741 gaataaatga catataatgg cacagcagca aacataaaca tgaactccaa tggttctgtt
    10801 acacctgtta gaaagacagc caacgctgct gaaaaataca ttgatttata tcttgctttc
    10861 ttatcaggat cgacattacg atacatcgca aaagccattc ccatcaagat acctgaagaa
    10921 ccaatcattt gtcctacttt gaaacgagcc ggcgtccagt tatgcaacac aaactcatat
    10981 tgcgacatat cccctgcacc tttaagattc actaaatcag tggcccaagc caaccataac
    11041 ggatcttgcc caaatacttg tgtccccgcc tgtgcgcctg ataaaatctc atacgatccg
    11101 ccaagctgtg tatagttgat aggaatcgtc agcatatgat gcaatccaaa tggcaatagt
    11161 aaacgttcta atgttccaaa taaaaacggt gctagaatcg gtgcgctttc ttgtgattct
    11221 gcaatccata aaccaaaatt attgattcca gcctgtacgt ttggccacac cacagcaaga
    11281 atcaatgcca cgattgttga ccataagata acaacaaacg gaacaaagcg ctttccattg
    11341 aaaaatgaca aagcatccgg caattttcta taattatagt acttattata agccattgcc
    11401 ccgacaaatc cagcgatgat ccctacgaat actcccatat tcaaagctgg tgcttccaat
    11461 acacttgtaa aaaatccttt aaccatgatc ttcgtaccga acagagtgtg ggtaaatgca
    11521 tcttcattcg caagcatgtc acttgtgaca ccaaagatag ccccagtgat ccgattgatt
    11581 aaaataaatg agatcccagc tgcaaatgct ccgcctgctc tttcttttgc ccaacttcct
    11641 cctattgcta aagcaaataa aatatgaaga ttaccaataa ttgcccaacc aatattttca
    11701 attactccgc ccgttgtgac aagcggcgtc caatcaggat tgatcaaggg aattgatttc
    11761 cctatactga tcatcaaccc agctgccggc ataactgcta ccacaaccat taaagccttt
    11821 ccaaattttt gccaaaactc aaaactaaat atctttttca ttccgtttag ctcctttacg
    11881 caatcggttt cgttaaacgt attatagcgt gcgttttctt ttttgtaaat gctttatttt
    11941 ttatttttct gtctatacca ttctataaaa cctataatac gtgtgttccc ttctataatt
    12001 ttctcctaaa aatttatttt tttaagcttt tttctatgaa atattttctt ttgtctattg
    12061 acttgtgcaa tcggttgcgt ttattatgaa cgtataaaac agctcattag gaggagaaaa
    12121 atgaaacaga tcaaacgact atttgctatt gatccatgga aaatcagcac gacacaatta
    12181 gataaaaaaa atcttcgact gcaagaatct ttaacaagta ttggaaacgg ttatatgggg
    12241 atgcgcggga actttgaaga aacttactca ggggaccacc atcaaggtac ttatttggcg
    12301 ggtgtctggt atcccgataa gacacgtgtc ggctggtgga aaaatggtta tccagaatac
    12361 tttggaaaag tgatcaacgc cttgaacttt atcgcgatag atatttcgat caacgatcag
    12421 ctgatcgact tggcttcttt ggaaccagaa gacttttact gggaattaga tatgaaaaat
    12481 ggtgtattat ctcgtacatt cacaatcact acttctacta ataaagtacg catttccttc
    12541 gaacgttttc tgagcattgt caaaaaagaa tcagcttata tctatttaac tatagaaatg
    12601 cttgaaggta gcggaacagt caaactcgta tcaaaattgg atggaaatgt tcaaaacgaa
    12661 gacagcaact atgatgaaca tttttggaat gagattgatc gtggaactat agaagaaatc
    12721 ggctatttga cgactaaaac tattccaaac aactttggga ttgaacaatt tactgttact
    12781 gcagcaatgc gccatttcgt taatggaaaa tcagtcatcc ctgactatca cgaagatact
    12841 ttagcattac atggttgctt gtctgcagaa ttatctcaag gtgagacatg gtcagtggaa
    12901 aaagaaatta tcgttcttac tagtagagat attccagaag cgcagcaagc agaaaaagct
    12961 gtctcagaat taacgaacca gacaaacaat tatatccaag caaaagaaga gcaaacagcg
    13021 gcttgggcag aacgatggaa gcttgccgat gtggtcatcg aaggagacga agaagcacaa
    13081 caaggtattc gattcaattt gttccaacta ttctctactt actacggcga agatgaacga
    13141 ttgaatatcg gccccaaagg attcacagga gaaaaatacg gcggagccac ttactgggat
    13201 acagaagcgt atgctgtccc tctttatctt gctttagcca aacctgaagt aactaagaat
    13261 ctgctgaaat atcggcataa tcaactgccg caagcaatcc acaacgctca gcaacaagga
    13321 ttaaaaggcg cgctttatcc tatggtcacc ttcactggtg tcgaatgcca taacgagtgg
    13381 gaaatcacat tcgaggagat tcaccgaaat ggcgcgattg cctatgcaat ctacaattat
    13441 acgaattaca ccggcgatac ggaatatttg aaaaatgaag gactggaagt tttagcagaa
    13501 atcgcacgct tctgggcaga ccgtgtccat ttttcaaaac gagcaaataa atacatgatc
    13561 cacggtgtga ccggcccaaa cgaatatgag aacaatatca ataacaattg gtatacaaat
    13621 acgatcgcag cttgggtctt gcgttacacg cgagaaaatt atttaactta tcaaaaagaa
    13681 gctgctatca ctatcagcga agaagaacta gccaaatgga aagatatcgc agagaacatg
    13741 tacttcccag ttgacgaaga attaggaatc tttgtccagc atgacacatt cttagataaa
    13801 gatctcatgc ctgtatccga tattcccaca agcgatcttc ctctgaatca gcattggtct
    13861 tgggacaaaa tccttagatc ttgcttcatc aagcaggcag atgtactaca ggggatttat
    13921 ttcttcaatg atacttttac aaaagaagaa aagcaaaaaa actttgattt ctatgaacca
    13981 atgactgtcc atgagtcttc cctttcgcca agtatccatt cgattttagc agcagaatta
    14041 ggaatggaaa gcaaagctgt agaaatgtac cagcgaacag ctcgcttgga tttggataat
    14101 tacaataacg acacagaaga cggcttgcac atcacttcca tgactggtag ctggttgtcg
    14161 attgtccaag gatttgctca aatgaaaact gcccatgatc agttgagatt cgcaccattt
    14221 ctgccaaaaa cttggaaagc ttattctttc catatcaatt atcgcggacg tttattgttc
    14281 atctcagtca cagatgaaca agttactttc gagttattag aaggttctcc tctagaaatt
    14341 tacgtctatg aacagtctta ttctttagcg gatcgtctag aaataacgct aagaaaggag
    14401 gaagcaaatg tttaaagggg tattgtttga tttagacggt gtcattaccg atactgctga
    14461 attccattat cgtgcttggc gaaagcttgg tcaggaaatc ggcattacga tcgaccacac
    14521 attcaacgaa cagctaaaag gcgtcagccg agaagactca ctctctttgc ttttagctta
    14581 tggcggaaaa gaacactctt tttcaaagga agaatttgca gaattagcga aaagaaaaaa
    14641 cgattattat ttagagatga tccagacgat cgaaccaaaa gatgtcttcc ccggggtcgt
    14701 gcctttactg gattctttaa aagaagaaaa aatcaagatt gctcttgctt ctgcaagtaa
    14761 aaacgggcca ttcctacttg aaaaaatggg tcttacacct tactttgatg ctattgccga
    14821 cccggcagaa gcaacaaacg gaaaacctgc gccagatatc ttcctccttg cagcaaaagc
    14881 tgtcggacta aaagcagaag aatgtatcgg gatcgaagac gcgcaagccg gtatccaagc
    14941 catcctctca agtggcgctc aaccaattgg cgtgggacgt gctgaagacc ttggagagga
    15001 gatcccgctt gtccctgata cgacttttct tacgatcgat tacttgaaag aaaagtggca
    15061 tgaccatgga taatccagag atctccgtcg taccagttcc agagactgaa ataaagaaaa
    15121 tcacattgaa gaacgactac ttagaagtcg ttcttctcaa ttacggtgcc cgcctgcacc
    15181 aaatcttcgc accagacaaa gaaggaaaat cagaaaatgt tttattgtct tacgatcgtt
    15241 tcgaagatgt tctaacagac aaaagctttt ttggagcaac tgtcggacct gtagccggaa
    15301 ggatccggga tgcttcttgg ggtgagcata gattggagaa aaactgcgga tcacaccata
    15361 tccacggtgg cacgaaaggc tggtctttcc aattttggga agtagaagtt ttcaaaactc
    15421 catcatcaat aggtgtggtc ttttacttaa aagatgaatt ttctacctat ccaggaccaa
    15481 tcactgctac gatcacttac cgtttaacaa aaaacgaatt agagatgaca acctctgcta
    15541 gtagccttgt tgaaaccatc tgcaatccga ccaaccatgc ctacttcaac ctttcaggaa
    15601 atggaacaag agacatctat gaacatcagt taacggtctt tttagatggt gtgcttgaat
    15661 tagatcaaga aaaactgcct actggaaatt ggacaaaaaa agaaaaactg ccaatcgact
    15721 ttagaaaatc cccaacactg caagagatcc ttgcatgtta tccagatgga ctagatgatg
    15781 tatttctttt gcatcatcct aggctttcca aaacttcctt acaattattc gagaagcatt
    15841 ctggtcgcca aatgactata gcaacttcta ataaaagtat ggtattattt tctacgactg
    15901 gattcgaagc tgatttctct gtcaatggaa aacagatgca ttcaaactac ggattagcaa
    15961 tcgaaccgca agaaatccct gatatcgttc atttccccaa atttggatcg atcaacctcc
    16021 atcctggtca agaacggatc agtcagacga tttatcggtt ctctgcacaa taacaagaga
    16081 aaggtgtttt tatcatggct attaccgtaa aagatgtggc gaaaaaagcc ggtgttgcca
    16141 cctcgaccgt ctctcgtgtc atcaacgatc atcctagtat ttccgagaca acaaagaaga
    16201 aagtccgaaa aattatggat gaactaggtt atgttcctaa catgactgcc cgcaatctag
    16261 gaaaacgcat ttccagtgcc atcggcgtaa tcttaccccc tcttgattca aaagagcgga
    16321 tcggtaaccc attttatctt gagatcatgg aagcaatcaa cgaagaagcg cggaattatg
    16381 atatgactac agcaatcgct actgctaaaa attttgaatt gctgttagag aacgtccagc
    16441 gtatgcattt acaaaaacaa gtagatggtt ttattctagt gtattcagat agtcaagata
    16501 ctgtcattga ttatttatac caaaaccaca tccctttcac tttgatcgga cagccttatc
    16561 atcatgagaa cgaaatcgtt tatgtagata atgataacca gcttctaggt aaacaagcaa
    16621 cagaattttt gatccagaat ggacataaga atatcctgtt tgtgacaaac acgactcatg
    16681 aaagtttgta tttcgaacga tatttcggtt atcaaaaagc aatgatgatg gctggtcttc
    16741 ctgcgttatc cagtgtagta ctagagcatc cggaggatta tctgtccttt gagaaaacgt
    16801 tgaaagaaaa cgaagccaca gcattggtgg tcattgacga tatcttcgcc cttcgcacga
    16861 tgcagttggc gcaaatgtat ggctatgtca ttccagagac actctccgtc attagcttca
    16921 acaactcgat cttctcaaca ttaacacacc cttaccttac aagtatcgat atcgatatct
    16981 ccgaattagg acgtgtcgct atgcaaaagc tgcgcgaatt gatccatgaa gaattgagca
    17041 gtggcgtacg tttggtcatc cctcatcgct tgatcaaaag agagacagtc gttcctttag
    17101 aaaacccata ctaaatagct gactcactaa atacgctgac catttatcct atggtcagct
    17161 ttttatgtaa aagaagatac tacttctaac acattgttta tctgtaaaaa agagcgtggg
    17221 acaaaagtaa agaacacttt tgtctcacgc tctaaacacg tataaacggc ggaagcagaa
    17281 gcaactcctt cggaaataag ctgaaattca caaaaattta aaaagcaatt ttcttgagtt
    17341 tcttcttatt tcttggagtt aaacgcttct gtcccagcct cttttttcct tccttcaatt
    17401 ttttacacgt cgacgattca ataaaaaacc gcctaatatt gtaaagacag gtgcaagaat
    17461 cgagaaaaag gcgaatggca agtaatgcaa cgcgctaact ttcatcgttc ccataatgaa
    17521 tgtgccgctg actccccacg gtacgagaga attgacggtc gcacctgaat ccgctagtgt
    17581 tcgtgtcaaa taggtttttg ataagccaac gtcatcaaaa gaacgcttga atgtttctcc
    17641 tggaagaatg atggacagat actgttctcc aacgatcaga ttgattccga tacagctcaa
    17701 ggcagtaaac ccgactaaac gagaaggtcg gtccatcttt tcttttaatt cttgaacgat
    17761 ggtatcaacg atcagatatt tgatcagtaa cccacctaat gccaatgcaa gtaaaatcaa
    17821 actagcagaa cctaacatac tcatgatccc gcctcgagaa agcagttcat ctagctttgg
    17881 atcaggtgta tttgcgacat aaccattcat caagatgtct gctgcttttc cgaccgtcaa
    17941 acttttctca tggataaaag aaagaacgag agcagctgtc gatcccgcta gtaatgtagg
    18001 gatagccgga atttttttga ttgccccccc aaataaaata actagtggaa tcaatgtcca
    18061 aggagagatc caaaagctcg ctttcatgtt ttggatcatt tcattgatac tagctagatc
    18121 ggctgaatga ctgttatgtc ctaatatcgt ataaaaaatc aacgaaagga cgaatgctgg
    18181 gaaatccgta taacgcatac cagcgatatg ttcgaataga ttaactcctc caatacccgc
    18241 tgccaagttg gtcgtatctg ataaaggcga gcagttattc cctaaaaagg caccggaaac
    18301 gactgcgcct gtagtcattg catcattgaa tccaagtaaa tgaccgatcc ccaaaaaagc
    18361 aattccaatc gtcgaaatcg ttgtaaatga actgccgaca gtcactccga caattgcaca
    18421 aacaagaaat gctgtcggta aaaagaaacg cacagaaaca agtttaaatc cataaaccat
    18481 aatcgtaggg atggttccag ataaaatcca tgaagcaact aagacaccaa tcaaaagaaa
    18541 aatcaggatt ggaatgatcc ctggagtgat tcctttgatg atcccgtcat ggatctcatc
    18601 ccatgtgaac tttttaaatc tgccataaaa caacaaacac atgaaagctg caaggatcgg
    18661 gatatgtggc gagagctgga atccgatgat cagtactcct aggagtgcca acaacacgat
    18721 caatacagcg atactttctt ttaaagaaat atttttattc atcgtcgatc tcctatttca
    18781 aatgaaaagg ccctgccatg aaaaaactat tcacttggca ggacctccta ctaaatcagc
    18841 gacaaaacgt cggctgaaag acttattttt ttatttttct tctaaacttt tttctacctc
    18901 aatcccccaa gaatctttct tgaagtgatt gatgatcaat ggaataacga acatgaccac
    18961 tgtgatagct gctactaata atgcatcact caatgtcgct gtacctaatg tagcaaatac
    19021 gacaacgatg atagagaaga tcagcatgca gctgactacc caagctaatc cgtttccgtt
    19081 tttaccaatt cggtaaggac gttcgaattc tggatgtttc ttacgcattt taagcaatga
    19141 aacagcaatc aaaatgtaca cgatacaata aataacagtt gtagcatttg taagtgtcaa
    19201 gaatacagca cttacgtcat ccattacacc ataaagcaaa gcaaataatg aaataacgat
    19261 tgattgtgtt agaacgacat ttctagatac gccgtatttg ttttctttat ggaatccgaa
    19321 ttttggtgga aggaatcctt cacgagctac ttggatgatt gtttttgatg gtccagtaac
    19381 ccaagctgat aattgtaaaa gcacaccaat aaataccatg aagctgaaga tatttccgat
    19441 cacttctggt aagcctagga tttgacagtc aatcaagata ggctgcgtga tatttgctaa
    19501 ttccattttt ccatctggta cgacatttgc tacaagcatc gcattgatga cattcaataa
    19561 aactaatccg atcaaagcga taaatacgcc ttttgtataa ttttttgttg cgtctttcaa
    19621 acgaggcatg taaacagaac tcatttcgat cccaacaaaa ataaatgtga taccagctaa
    19681 gtatttcaat gaatcaatat gttccaagtc agggaaagct tttgaccatg aaaagtcacc
    19741 tagatagccg tttgagacta gtccgacttt gaaggctgcc aaaacaccta aaacgaacat
    19801 gatgactact gggatatata cccctagcca tacaccgatg ttcccgccga cttttgccat
    19861 atcgaatttc aagttcaaga tcgtgatgat ccagtagata actaaaatac aacctaaaac
    19921 gaaccagtga ttattgccaa gttctacatt accaaatgtg tttcctaaca atggtcctaa
    19981 agtagaagcg accattacca tacctgggaa catttgcacc cataatagcc atgcaacgac
    20041 aaatccccat ttgctgccca gtgctgtttt tacccataac tgaggaccgc cttcttgagg
    20101 aagcatcgtg gaaagctcac cggaaaccat tgatatcgga ccggcaaaaa acaaaactgc
    20161 aaaaattgaa taaaaaatca atgtccaacc gactgcggct aacgtaggaa tactccgaac
    20221 cgttgcacac agtgccattg tcagaccgat aaaggtccca agacccattt tacttacttc
    20281 agatttactc accgttgaca ctctccttga ttttttggat aaaataacgg tgtctttgaa
    20341 gtagtttcag caataaacga aacaattcag cgaatatttg aggggattct ttgagtttat
    20401 tgcttgaagg gtttcttcaa agacaacctc aaaacaaagg gatcgaagag cttaggtctc
    20461 cccttgctct tcagatccaa acatgcgtca gaaacagtta gtattcaagc tgttttctaa
    20521 catgattacc ttgcttattt tgcttcgctt gccaataatt ggtctgcgta gattttttcc
    20581 aatttttctt gaagagctgc tttgattttt tcagcatatt cttcaaagtg ttcttctttg
    20641 ttcatgtatg gtgtcattac gctggcacgc aatacagtta cttttccggc acggttccat
    20701 tcttcatctg agaatcctag ttggttcaca aattgtaatg ggctgttgcc atagtctggg
    20761 atagcaaagt cagtatgtga agttaagaac tcattaccgt aaatgcttcc tttcacgtat
    20821 gaagaataat catatacgtc atggttcaat ttattcattg caactaagtc atcgttgcct
    20881 ttttctttga atacatagtc taccatattg aaatctggat aagttaatgg atgaacttcg
    20941 atttctttgt ctcctacttt aaatgacaag tcattcaaga agttgtagaa acgatgtgca
    21001 ccttcgattg atgcacccat taatttacca tatcctgtga cattcaaagg taagacatgg
    21061 tgtgctgccc aaacgctggc tgctgttgcc cctgcttttg aaccttccaa gatataagcc
    21121 ccaagtaatg ctgggatatc tgcgcctttt tcaaatacat atgtcgcaaa gtaagagata
    21181 acgtctctca tgcggatatc tttgatgacg ataccaccgg cagaatatgg aacatagccc
    21241 attttatgtg ggtcaatcgt tacagattct gcttcttcga ttgctttata tgcactgtgt
    21301 acttcttcta agatataatc tttgttttct gtaaagacat tgtatttgta atgaacatct
    21361 tttaaatctt caaatggaat gaagttgttg tcttcgtcta agaaaatcgc acggccgtat
    21421 ccgccataag cagcatctac gtgtaagtag aagtaaatac cgtctttttc taatacgcga
    21481 cgcaatgcaa cgattttatc gataccgtcg attgctcctt cttctgttga tcctacaaca
    21541 ccgactacac ctaggattgg tgttttttca gctgctagac cacgaacgat tttttcaagt
    21601 tcgttgatgt ccatgcgata gttgtggtca actggcactg gaatcacttg gtctaaaccg
    21661 ataccgatga tgtcggcagc ttttagccat gaatagtgtt tagtttgtgg aaccaaccat
    21721 tttcctaatt tttctaaatg ttttccgcta cgtgctgagt gagctttgat ttcgtcgatt
    21781 ttttctggga cgctgtctaa cagattcatg atttcttctg ttgacaagtt cattaattcc
    21841 caatcgcttt ttccagcaac tagttcaggt gtcacttctt tcattgcaag cggcaatgat
    21901 ttgatgttgc gggcatacca aagtccttct aagtttgcta aagaaccatc agcaacgatg
    21961 tggccccagc catctttata gctcattaat tttgcaaatt ccattcctac ttcttcttcc
    22021 atttggcttg ttgcaggaga agattcatag gcaacgttat taccattcca tagcatagca
    22081 aaattgtacg ctagtaaaga tggcatcaat gtttcagagt tcatatgacc ccagtaacgt
    22141 ccggcattat gccaaggaac ggaatgggta cgcatccgcg ctgaaatttc tgatagaaca
    22201 tcctttgttt tattcacagt gtgttcaaaa ctagcactgc ttttttcttc tggcgtaata
    22261 ataggcatgt cttgaggcat gtagttttga cgccagccta aatgttcatc caccaattca
    22321 ttcaacaaag ctttatagat ttggccgttc tcagctttgt ccccaatgaa tagggcattt
    22381 aggtttagat ctttcgacaa tgattcactc atagtgaaac cctcctaaaa aaatatttaa
    22441 attttgtcga gccctacatt acacctgttc ttctattctg taaactaagt tttggcctga
    22501 tttttaatca tattttaata tgtatcaatt atccgaattg ttcacacttt tgaaataatt
    22561 aaaaaaaacg agggaattta caaatgtaaa ctccctcgca aagattgtat taacgacaac
    22621 cagcgttcta ttttaggatg ggtttcaaaa ttggaatgtt gtaatagtat ttcccttttt
    22681 caaggtaaaa acttactaaa ttctaatcaa ttactttggc caaaaagtaa tttttcttac
    22741 cttttcgaat aaccacaaac ttaccatcga attcatcgga tggatttatg acaaaattta
    22801 aatcggtaac gcggtcaccg ttaatactta tagctccgtt tgaaacatct tcacgtgctt
    22861 gacgtttaga tggttcaatt tttgtggaaa caagcagttc cacgatattt tcaggtgtgc
    22921 ttgaaatttc aacgttcggc attttaccga atccttgcgc gatttcttcc gcatttagtt
    22981 ctttaatatt tccagagaac aatgcttgcg ttattttttg cgcttctttc aagtcttctt
    23041 cactatgcac aaatcttgta acttcttctg ccaaacggcg ttgtgcttca cgtttctcag
    23101 gttctgtctc tacttttttc gctaagtctt cgatttcttc ttgagacaag aaagtaaaga
    23161 atttcaagta tttcactaca tcgcgatcat cttgattcaa ccagaattgg tagaactcaa
    23221 atggtgaagt tttcttcgga tcaagccaaa cggcaccgcc tgcagttttt ccgaatttcg
    23281 ttccgtcagc cttcagcatc aatgggatcg ttaaaccgaa cgcttctgct tctggtcctt
    23341 ctaattttcg gattaggtct aatccagctg tgatatttcc ccattggtct gctccaccga
    23401 tttgcaattg cacatcgtat gttttatgca gatgcaaaaa gtcgatagat tgcaggattt
    23461 ggtaagtaaa ctctgtaaat gagattccta cttccaaacg gctggcaacg atatcttttg
    23521 ctaacatcgt gttgatgttg aagtttttac cgtagtctct caaaaattca agtaaagaga
    23581 tttttgacaa ccagtcgtag ttgttcacaa atgtgatatt tgcatcttta ccaaacaatt
    23641 ttctcatttg attggaaagt gcgtccacgt tatgttgcac ttgttccatc gtttgcaaca
    23701 cacgttctgt tttgcggccg cttgggtcgc cgatcgttcc tgttccgccg ccaatcagaa
    23761 tatatggatg atggcctgcc aattggaatc ttttcatcat cataaatgga atcaaatgtc
    23821 cgatatgcat cgaatcacca gttggatcaa cgccgcaata aagtgaaatg ctcttttctt
    23881 caacgagctc gcgaagtctt tcttcgtttg tttgctgatt aatggcgtcg cgccaagtta
    23941 attcatcaat aatattcatt ttactgacct ccgtgtagtt tttttatgaa agcaggaacc
    24001 tgctagcata tgtaattaat tatttcttca ggataggata ggaaataaaa aaagtccctt
    24061 ggcatataag ccaagggacg aaatctcgcg gtaccaccca atttgtatgt ctagatatcc
    24121 aacatacctc tcgaacattt aacgctgtcg cgtggcaatc actgccaaag actcctgaaa
    24181 tgtaattcgc tttaaagcat gtactggttt gcagcgacca ccagctttct gaaacattgg
    24241 ctttaacaac tacttcgttt cgatcttcgt cttgttatta ttaatatgtg tctatcatag
    24301 agcgcaactt tttctttgtc aacagaaaaa ggatattttt tttaaattcc tcattttttc
    24361 ttttttgaat ccgctctaat tccgaacatt ttattttcaa ttattgttaa aagaaataac
    24421 tttttctgta ttttttctgc aatttatcga gaagtcactt tactttgcct cttattcttt
    24481 cttcgttaca ataaggaatg ggacaagtaa aaaaatgaaa aagcaaggga cgaggtatat
    24541 ggaaaaaaag caaaaaatta ttttaggagc cacttctgct ttaactatcg ttattttaat
    24601 tctaagtttg ttttttgtca tccgatcatc tacaaaaaaa gaaccaatca ttcctgaaaa
    24661 aaaaataaca gaaaaagcaa aagaaccgac agatgataag caacaactag ttactcaagc
    24721 aaaaaatctg gctcaaagct acgattatga ccaagcgatt gcgttattgg aaaaagatag
    24781 taagaacgga tctactgaaa cacaacagct tcttcaaaca ctaaaaaagg agaaagaaca
    24841 actgatcgac tggtctgatc ctactcagat ctctcatgtc tttttccaca gcttgatcgt
    24901 ggacccgcaa aaagccttcc actctcaaca ggcacaagga tacaaagatt atatggtgac
    24961 tgttgaagaa ttcaaccgtt cgatcgaaca actttatcaa aatgattttg ttttagttaa
    25021 tttgaatgat ttgatccaaa aagacgaaca aggaaatctt tcctttaacg ggcttgcgct
    25081 acctgaagga aaaaaaccat tggttctttc acaagatgat gtcagctatt atgaatatat
    25141 ggataattcc ggttttccta gccgattggt cgtatcaaat aacaatgaaa tcaaaaatgt
    25201 ctataaagag aaagataaag aagaaatcgg tgactttgac atggttcctc tgatcgatgc
    25261 ctttgtcaag aaacatcctg atttttctta tcgaggcgca aaaggtacct tggccctgac
    25321 aggttacaac ggagttttag gttatcgaac atcaaaatct caatatggag acaatgaaaa
    25381 aacaaaaaaa gagattaaag aagctaaaaa agtggcggaa cagttgaaga aagacggctg
    25441 gagctttgct tcccatacat ggggtcactt gaatatgact caagcttcac tagaagatgt
    25501 aaaaaaagac aatgaattgt ggcagcaaga agttgcacct atcctaggaa aaacaaatat
    25561 tctgatttat ccatttggtg cagacatcag cgactggcag ccttattcag cagaaaatca
    25621 aaaatttgct tacttgaaga gtcaaggttt cgatattttc tgtaatgtcg atgcttctac
    25681 accagcttgg ggacaattag gtacggattt ctatcgaaat gctcggatca atatcgatgg
    25741 cattcgtttt caatctgatt tagacggaaa aaatcctatt cttgatccat tcatcaatgt
    25801 ccatgatgtc tatgacaaag aagcacgcga atctgcttga ttttacgtca tttatgaacc
    25861 aaaaaagccg aactgacatt ttatcgtcag tttcggcttt tttatgcttt atttcttctt
    25921 cggtgcgatt cccttgatca ggacttctgt ccattctgct gtatatggaa gcagttttgc
    25981 gtatatctcc ggcttagaaa ttccttctac cattgcttga aaatagagga tcaagaactc
    26041 atccgaatat ttcaaatcca cttttccttc tttccgccct cgatggaaaa gatcaagcat
    26101 gatactgaaa ctttcttgcg tatacgcatc catcgcgtca gaaaattctt ttttttcttt
    26161 ttttgtatag tatgtcatca aatcgatata aaattgtttg ttcactcgat tgagataacg
    26221 gattttgttt tcactcatgg caatcagtgt ttcttcaaat ggaagatttt ccgcaatcaa
    26281 cgctttcgct tcttgcccta aatcattcat aaatgcaaaa aatacttcat aaatcagccc
    26341 ttccttgctg ccaaaatatt taaaaatcgt cgctttactt acctgagcgt tctcagctac
    26401 cttatccatt gtcactccag cggttcctat gtctgtgttc atcaagtcaa aagctgcttg
    26461 taaaatctct ttctttttct cttgtgctct cttttcaaaa ccgttcattt gtagagcctc
    26521 ccgtaatttt aaacttttat aatatatata gttcaaattt attctgaggt ttattataac
    26581 tatctattga gaaagtatca agctagcaat tccttgttta tgaattcatt gacagaaatt
    26641 tataaaaaga atattatgta ctaaaataat aaaaaaagtt ttataaaaag gtataaaacc
    26701 tttttattaa actatttaat cttgtttagt atatattttt agaaaaagga gtggggtttt
    26761 tatggcagaa atcgtcaaag tcacacattt gaaaaagagc tttggtcgtt tcgaagcttt
    26821 aaaagatgtc tctttcaccg tacattcagg tgaagtcgtt ggatttatcg gaccaaatgg
    26881 ttctggaaaa tccacgacga ttcggacact tttagggatt ataaaaaaag acggcggaac
    26941 ggcaacgatt tttgggcaag atgtatggga agatagttta tctatccatg aacgtctttc
    27001 ttatgttcca ggcgatatct ctttgtgggg aaatttgact ggaggagcga tcatcgatct
    27061 cttcatgaag cttcatggaa aagggagtgc tcaaaaaaaa gatgaactga ttcaacgttt
    27121 ctctcttgat cctaagaaaa aagcaaaaaa ctattcaaaa ggaaatcgcc aaaaagtggg
    27181 cttgattgct gctttggctg ttgattcgga tctctattta tttgatgagc ctacttctgg
    27241 tttagatcct ttgatggaaa cgattttcca agaagaagtt gaaaaattga aagaacaggg
    27301 caaatccatc ctactttctt ctcatattct cagtgaagtc gagcgactag cggataaagt
    27361 cgtgatcata cgcgaaggaa cactcgatga agaaggaaca ctcgatgaat tgcgtcattt
    27421 gactcgttcg accatcacta tagaaacaga agcagagaat agtcacttag cacaattgaa
    27481 cggtgtccat gactttgtgc aaaaaggtca cctcgctcaa tttgctgctg ataacgaagc
    27541 tttcgatgtg attttagctg aagcgtccaa attaggtgtg aaaaaatttg aatctattcc
    27601 accgactctt gaggatttat tcatgagaca ttatgaagga tgaggaggaa gcgaaatgac
    27661 tgataaattt tcacgctggt ccaccctttt ttctcaaaac cttagccgtg actggaaaaa
    27721 gatcctgata tggctagtcg gtgtcactgc tttttctggt ggttttgtcc ctgcgtttga
    27781 agaattgact tccggacaag gattagctgg attatacgaa accttgcaaa acccggcaat
    27841 gattgcaatg gtcggaccaa ctccagcttc gaatgctgct gagtatactt taggagcgat
    27901 gtatgcaaat gaaatgttgc ttttttgcag tttgtttgct gctgtgatct ctgttttaca
    27961 cgtggtgagc caaacgagaa aaaaagaaga acttggtctg attgaactta ttcgttcctt
    28021 tcgagtcgga cgtcaagcaa actctttagc tgtcatcgct gaaagtattc tgatcaattt
    28081 gcttttagca atatcgatca gctgtacgat gatttttttc caagcggatt cgatcactgc
    28141 agaaggtgct tggctttttg ggctatctgt aggtagtatg gggattttgg ggagtgccgt
    28201 tgcactgttt gctgcacaac tgatgccaag ttcagccagt tcgaatggtc tgtctttagc
    28261 gtttttaggt ggactttacc ttctacgagc aataacagat gtagctgatt cctccctttc
    28321 gatgtggaat cctttaggct ggtcttattt gacctatcca tttacaacta acaactggat
    28381 tcctttgctt tatttgtttt tgttcagtct aatcttgata atcagttcat ttgttttaga
    28441 ggaacatcga gatttgaaca ccggctatat ccccgaacgt gaaggaaaac cgtatgctaa
    28501 acgttctctt ttatccttgc gtggtttatt attctatcta aataaaggga tgacaatcag
    28561 ttggcttatc acttttggtt tgatgggggc ggcatacggc tctatctacg ggaatatgca
    28621 acagttttta gaaagtaacg acttaatgaa acagatgttt atccaatctg gcgtctcaat
    28681 tgaaaaaaac tttacaagca cgatcatggt agtcttgatt tgtctagctg ctattttacc
    28741 aattgctagc atcaatcgtt tatttacaga agaaacccac ggacgtatga atcagctgtt
    28801 cgcaacaaaa atttctagga accaacttta ttggaccaat atgttactag ctattctatt
    28861 tgctatattg gcaatcctga ttagttctgg tgcactaggg ctttctgctt tggcttcgat
    28921 gaaggatgcg aaagacatgg atctattgat gtttcttaaa gccgggttca atttcctgcc
    28981 tgccgtttta gtgtttatcg gaattagtgg ctttctattc ggatggcttc ctcgaatcgg
    29041 taaacttgct tatatctact tagcttactc ctttgcactc aattactttg gcggaatttt
    29101 ggatttacca gaatggtttt ccaaaacagc tgtccctagc tgggttccac ggatgccaaa
    29161 cgattctttt gatctttccg tgttccttac gttatcatgt atcagccttg cactgttcgt
    29221 ccttggttct attggttata ggcgaagaga cttactagaa ggataataaa aaagcatgta
    29281 caatttcatg ctagcctcca aatctgggtc aaaaatccaa catttggagg tcattttttt
    29341 atttacaagt cttctaactg ctctttatca atgatccaga cttctcgatt ctttcttttt
    29401 acataaccat tctcctctaa taatttaaat tttctagata aagtttcggg ggtcgtaccg
    29461 ataaatgcag caagttcttt cattttcatt ggcaggaaaa agtgatcctt ccctgtcgct
    29521 ttagctaagt caagcagata gacagcgact cgttcttcta ctttttccat catcaaaaaa
    29581 gttgtctgct gctgtacttt tgttaatttc tcaacgttga ttgctaaaag tttcagacta
    29641 agggcgggat aatgcagtaa gagttccgag aaatcttttt gtctcaatat gcaaatttcc
    29701 gttttttcta gtgcttcgcc aaataaagac tcatttggaa cgcctagcaa ctggctctct
    29761 ccctcatatc cgcccggctc tattactcgt aaaagctgtt cctttccgct agcagataat
    29821 tgatacactt tcatactgcc ggaggccacg atcactaatt gaggttctcc attcggcgca
    29881 agaatctgtt ctcctttttc cacatagtga tgtttgacaa gtgcgtgtac tttttcttga
    29941 tcttgctgta ctaagtgatt gaacaaagga acaaatgaaa cacataaatg atcatgactc
    30001 ataatctctc ctccttctaa acagctattt ctaataaaga aacataactt cccttattcc
    30061 aactgataat tttcttttat catagcataa acgtcaagcg aaccagatac cagcaaatag
    30121 agtggatttc tttttgtccc ttgctttatt ttccttcttt tgagacctta agtaattgat
    30181 tcctatcaat tttttaaata tttacttttt gaataatcaa aaacaaacct tcactcgcaa
    30241 gccgagagta aggtttgttt ttcgcattgc ttatttcgtg ttgtctattg aaatttttcc
    30301 gcacctagct tttgatatag tggtgctagt tcttgtaagg tttcagcggt tatttgctca
    30361 acgtgttcga tttcttgcgg atagaagaat agtttaccca tttgaaaggt tcggtctctc
    30421 atcgcttttt tcaactcttc ttgtttcttt gtatcggaca aatagtcaga caaagctaag
    30481 tggtcgtcaa gttcatgttc tggttgcggc catatgtaat aatccttgat atcgactgtt
    30541 ttgctccact ctttcagtat cgcaagcaac tggttatacg ctgcaatgct accatatcgt
    30601 tcttcgcttt tataatgttg gtacatcaaa tagatttggt attgtttttg attcaacaaa
    30661 actgctagac aggcattctc gtcttgacga gattcgcttc ggtacgcgct ccaaaaatga
    30721 ctgcgtaaat tccagccatt cgtccagctt tcgattttag gtttgctcat gccgtacata
    30781 tcaggcaaaa gtgcagctgt ctggagctga atctctttcc atttttgcca gtgttcttta
    30841 tattctttct tgatttgttc aatcttatct gttggatggc tctctttgag ctgtttgaat
    30901 gcgtagattg gtcgatcaaa caactgataa tctgattttc caagttccat tgtttcgcct
    30961 ctttccgtta tcttttgtat tctacctgaa ttttgcgata tggacaaata gaggttgtga
    31021 aaaagctgtt ctgcatcaag tcataagaac agccaaacaa aaaactgcga tgagcatcac
    31081 cgcagtttta ttgaacttaa ggttgattga tcacatctaa aagcgttgaa aataaaatgg
    31141 cactagaagc agctcctggg tcgatatgtc cgattgcacg ctctcctaga taggaagctc
    31201 gtcctttttt agctaccaag actttggtgt gttcttttgc ctggtcaatg atttcttttg
    31261 ttaaattccc tgccttcaat gcctctgtga ctggcagcca aacatctaac atcgttttat
    31321 cgtcagcttc tgcctttcct cggctttgaa tacccgctgt tccctgctcg atcacttcgc
    31381 ctaatttttc ttgagaatca atagaatcga cctcttttgt cgctttcatc atgttcatga
    31441 atgcagatcc gtataacgga ccagaagccc caccgacttt cgatatcatc gccatagaga
    31501 atactttgaa tgtatcgctg attgtttcag gatgatcggc ttgaaaagct tcttcataag
    31561 ctgaaacccc tcttcccatg ttatttccat ggtctccatc gccaatcggg gtatctagat
    31621 cactgagata ttgtttgttc tgattgattg cctctgcaaa ttgcgtgagc cattcttgga
    31681 tttcttgaac ggttagtttc atattatcac ccttttatct tgagattttt taccatgaaa
    31741 tcgtctgtac attgctttct aaagaatctt tccattgtgt ctccgtcaag tcgatcagtg
    31801 ttagagaaag accttgcata tctagtgagg tcataaaatt accgactttt cggaaaacta
    31861 cattgacgcc tctttcttcc aacagagcta aaacatcatt catgaacacg aactgttcca
    31921 tcaaaggcgt cccgcccatt ccgttgacta gtacacctgc ttcttttggt aaattcgagt
    31981 aatcatctaa aatcttagta acaagttcct ttgccagtac tttagaaggc tgcatctttt
    32041 ctcgacgata gcctggctca ccgtggatac caacaccata ctcgatctca tcttctccta
    32101 gttcgaatcc tggtttccct acttctggta cagttgctgc tcgaagcgct agaccgatcg
    32161 tcttagttgc ctgtacgacc ttttctccca gttctttcaa ctcagctagg gaagcaccgt
    32221 ttcttgctgc atcgcccacg attttgtgta caaggacagt acctgcaact ccgcgttttc
    32281 cagcagtata cgtactattt tcaacggcga tatcatcatc tacgatcaca ctttctactt
    32341 caatatcgtc catagcagct aattcctttg ccatatcgaa gttcaatgca tcccctgtat
    32401 aattcttaac gatcagcaaa actccttttc cactatcggc ttccttaata gccgtctgaa
    32461 tctgatctgg agttggagaa gtaaacacat caccaagcac cgctgcactt aacatccctt
    32521 cccctacaaa cccggcatgg gatggttcat gtccgcttcc tccaccagaa accaaaccaa
    32581 cttgttccgc tttctgattc ttggctacaa cacgggaaga ttctacacga tgaacaagtt
    32641 ctggatagct ttttactaat ccttccagca tttcttcgac aatattgctt ggatcattca
    32701 tgattttttt caatttattc ccatcctttc tttccggcat tttgtgcttc tgttaagatt
    32761 tgctgagtat catctgttat accggcagtg atggctgctg caaaagctcc ttccactaaa
    32821 ggcgcatcca ccagatgata acgttgctgc tgctcttctt ccaacatgtc ttttgccagt
    32881 tccgagttca ataccgcgct accgatatcc gcaaaaacaa aataactagc tgcatcgctt
    32941 gattcattga ctgcttctac gattttcatc gggtctgatc cgatctcgcc atttattccg
    33001 ccgagagaaa aaatttgcac ctcttcggat ttttgcatct gctcaatcat ttctttaata
    33061 ccatctgtta ctttttgact atgagaaata agcaaaatac tttttttcac aagaatcttc
    33121 ctttctttta catagttgct aacgattggt ttcgctttca ttaatgaaca attcaagtat
    33181 ataataaatt tctaattttg ggaaaatatg tgtagtgctt cttgaagttt gttatacttt
    33241 aattaaaaga gaggagtgat cgaatgatta caacaacaac gaacagtgta gagggaaaag
    33301 ccgtagtagc ttataaaggg atcgtttttg gtgaggtcat tactgggatc catgcattta
    33361 aagacttgga ggcggggttg cgaaatatct ttggcggccg ctcaaaaagc tatgaaaacg
    33421 aactaatggg tgcaagagaa gaagcacttg ccgaaatggc cgaacgtgca aaagcattag
    33481 gagctgatgc gatcattggc gtaaaaatgg actatgaagt attaggcagc gacaatggca
    33541 tgctgatggt cacatgtagt ggaacagctg tctccacgag ataagtaggg gacatctgtt
    33601 ttaataacta aagagagatg ggacatgtag tggcactcaa gaattagatt tttcagtcta
    33661 acttcgaggt actctacctt cccatcctct cttttttatt tctttttgcg gatgattccg
    33721 taagctgctg cgactaacac acccgcccct gctaaggaat aactgacaga agctgttttt
    33781 tcatttgttt ttggcaaagt ctgacttgtt gatttggatg gctctgtcgt ttgctgaact
    33841 gtttctgtcg tgcttccaga ggtcactgat ttttctcctg ccgaatgcaa aatatctttt
    33901 attcgttgga aactagctgc taagtcagct ttttttgctt caaaatcatt agcaactgtt
    33961 tgtgcttcgc tgatctttcc gtggattgct tgactggccg ctgtgatatc cgcttgagtt
    34021 tgacttagct ttccagaagc tgtttgagca acctgattta attgctgatt gaattctttt
    34081 gcttgttgga tcttcccgtc aagatctgtt tggacagctt ccgcttttgc tttcgcttcg
    34141 gcaagctttt tctcaagttg tgcacggtca tttcccactt tatttttaag atcagctaaa
    34201 tcttgatcga ttgctgcttg gtcttctttc aatttgtttt ttgcagcttc taatgcttct
    34261 tcgagttctt ttcttttatt ttccaagtct tgcaaatgat cgatttggtc agaagaggta
    34321 gaactattta ttgatgtatc ttctgaagat gaaatcgttt ctcctgaatt atctgtcggt
    34381 acattggaag tcatttctgt ttccgaggca ccgttttcag caccagaaga gcttatggtt
    34441 gttgaaggtt ctgtttgagc aggttcagaa gtttccgcaa aagctgtctg tcccaataag
    34501 aaaatactgg aaacagcaat tggccagatt aacggcttca ttcttttttt catcactttt
    34561 cccatcctta ctacttttta actaatttct tattataagc aaaaatgttt ggaagaacca
    34621 taaacacaac aggctgtttg tctaaaaaac ggtgcatctt ttattttttt gtacgttccg
    34681 ggcttttcca tgtcccgctt ccataaccta aaatcgtttt gactgctgga atgaaagtcg
    34741 tcacgatcgt tatcgcgttc actatccaga acaaaagcat atatagtggt gcgaaaagaa
    34801 ggtatttcaa ttttcttcgt cgatcatcta caatcagcga agctagcaac tggaaaaatc
    34861 ctgcgaccat ttcaaagcag atgaacacaa aactgaatgt aaaagtaata taaatctgtt
    34921 cgtagtttcc ttgatataca taatgcccga ttaatccagc aaaaagaact acggaaatac
    34981 aaaagaatat tgaccagaca atactcaatg tttgatcaat gaagatgatc gttcttccaa
    35041 tatgtttaaa aggatggagc atcacttttt tgaaattcgt cagccagact tctgttccac
    35101 cttttgccca acgttttctg tgtcgatata gcatcttcaa cgtcacaggt acttccatga
    35161 aaaagataat ctcaggagca aaaacagata accagtcatt taactgatga tcccaagcaa
    35221 tactgatgtc ttctgtcgct cgatcttgtc tgaatccgcc cacatcgatc aaggcttctt
    35281 ttcgatacat cgtatttgct ccactgtacg cataaagacc accgaaaaca gctgactgtg
    35341 ttcgtttaat gatgcccacg atacttgaga attcaaccgt ttgagatttt gcaatcaatt
    35401 tggtacgatt ttggacatcc atatttgcag tgaccgcagc aatatgtctt gcaccagggc
    35461 gaatgaaata attcacatac ctaatcagtg catctggctc cggtaccgtg tctgcatcat
    35521 tgcttaaaat caatttccct tttgcaaagg caagtccgat attaaacgcg tgggcttttc
    35581 ctttattttt ttcgatccga accacacgaa gattagcgta ttttttcatc agtctagcta
    35641 atatttctgg tgtttggtcc gttgaaccat cgtctgtcac taatacctca tagttgtgat
    35701 aattcaattt cgtcatcaaa tactcgattg tatattcgat cacaatttct tcattatggg
    35761 ctggcaccat gatcgtgatg aacggttcga cactcaaggg aacatctacc cattcttttt
    35821 gcttatgttt gtataaaaac acataacacc agacaccaat aaaccataca aatccgccta
    35881 aaatcggata agaaacgaga aaaaaataca taatagacaa acaagtatct aagaataaat
    35941 tacctgtatg ggtgattgag atcatttcag ttccacccca ttttctttat acaaatctgc
    36001 aatgaatgtc gtatctagat ttttctcttc ggagacagaa taaaaacgga ccgtttctct
    36061 ctcttctttt gttccaaaac gttccgtata cacttcttca agtaattctt gtcttttttt
    36121 caatttttca tcttcatatt caaaagattt atttactttt ttgtatagat ttcgattgtt
    36181 ccacctagtc aatacaaatg aggtaatcag gaaactgaaa aaaatcaata caaaaaagcc
    36241 gattaagaaa tacagcattt tcttttctga taaaaaagcg tacaaggaaa aatccttggc
    36301 tctttctggt ctcgttaatg ggaaaaagac ccatataaaa ggaagaacaa cgatcatcca
    36361 tcctaaaaga gccactaacg tttgccaaat ctttaaccag taattacctt ttgaaaaata
    36421 cttatctttc accaaaattg atgcaacttc ttctcttgtt acttttttca tatcctcacc
    36481 tcacgttttt ttgttacgac gtaggagttt accatacatt tcatttcttt tcacataaag
    36541 tgttcctaaa tttttcctaa gaaaaagaac aaaacatttc tcatcagcaa atgaaaaata
    36601 ttttgttctt tttatcagtt gttcttttta ttttttatct cttaattatg ttgctctttc
    36661 caatacgaca atgcttttca ttcctctaga tatcgccgtg tacatttgtc tgcgtcttct
    36721 ttgctcatct ccatcgtttt caaatggata taagattaca tgatcaaatt ccagtccttt
    36781 tgctagactc aaaggaatga tttggcagtt ttctaatcca tatgaatttt ttttaatcga
    36841 ttcttgtagc gtttgggttt cctcttctgt ttgggtgata actgccgctt tttctccttt
    36901 tagagaaacc aaaatctcag ctagtatttt caacaattct tcagaggatc gaaaagagcg
    36961 gtattcgggt tcttttcctt gcggtcggat cgatacgatg tcgatcttct cttgatccac
    37021 agcataggtt ttgaaaagct ctgtgattgc tccgctagaa cggtaactat ttctaagatc
    37081 ataccgatgg atcggcagat ggtagtcgtc gaaacaacgc ataatatcag caaaagtagt
    37141 ggaagaatta aagattgcct gattctcgtc acctactaaa gtaaagtgag tttttggaaa
    37201 taattcgatc aatagaccta attgtgccag ggtataatct tgtacttcat caatcaatag
    37261 atagcgaaat gctggtacat ttaccttttc aacaagtaaa tgacgaatag ctaatataat
    37321 gactgcttca tcaacagtac gtgtgggttg ccaagcataa gctgagccat atcgtttttc
    37381 ataaattctt tcaaacaact gatgctcatc cacccatgcc atttcttcga tttgtctggt
    37441 tatttttcga tatttttttt gtaaaagttt ccttgcataa gctacaatac tttgttccga
    37501 atcatcagaa atcaatttac cgaataattc caactgccta tcttctgtca acgagagtac
    37561 ctgattctgc acagcaggac tttttgcttg tttcaaaaga tgattcttcc attcgctcat
    37621 cagtgccttt ttcgttgctt gaagcctatc gatcaattta ggatgagcag gaactttctc
    37681 atatattttt tcgatcgttt ttttagaaag gactgttttt ccatttttag taagtccacg
    37741 gataaaattc ggatgatcta aaaacaaagg atctgattgt tttagattat cgataaactt
    37801 tttgctacgc aaacgttctg tctgctccga tacattttct cccgtgatac gtttgaaata
    37861 agcctcttca ccttctattt cctctgctga aagctgtgaa accagctgta tgatggttag
    37921 attcagtgga tttctttcac ctaatgatgg taggacattc gaaatatagt cgataaaccg
    37981 atgattaggt gatagaatca gcaagtcatc ggatgtcatc gtatctcgat ataaatagag
    38041 cagatacgca atacgctgca tgatagcaga ggttttacca cttcctgcta cgccatttac
    38101 caagatattt tgacttttca catcccgaat gattgtgttt tgttccgatt ggatcgtagc
    38161 agtgatagcc ttcatttcat tggtctcatc ttggcctaag acttctaata atacgtcatc
    38221 ttgaatagct acagacgtat caaaaaactt gaccaaacga tctctttcca aaagaaattg
    38281 tcgtctttct ttaataaccg tatcgatttt attttgacga accgtataag aagatggacc
    38341 aatcatgtta ttgtaaaaaa gttcggcaat tggtgaacgc caatcataaa caagattttc
    38401 atctgcatca tctgtgaaat ttgctgtacc gatataaaag gattcttttg gctcattatc
    38461 cagaaagtct acaacgactt ttccaaagta gggacttttc aataaacgtt cgatctttgc
    38521 tagctgattt tctgcgtttt tctgtttgat attcatctga tcgatttctc tatttttcat
    38581 ttcaatcatc gaaaaagtat ccaggttatc taagtaactg tcaaaattca atcgaagctc
    38641 gccagccatt tctttcaacg actggtttcc ttctattttt gccgtatcca tcgattcccg
    38701 cagttcgttt tttttatcaa ttagcttttg atacacgttc ttcagatatg cttcttctaa
    38761 ctgtttttgt gtgttgacca tacacattct cctctttttt taaagtggtg gaaccgatta
    38821 gtttacctct tttaagagtc gaatgcaagc tttttaacga gtatcatttg ttaggatata
    38881 tcagttcttc aggtcggaca gtttgatata aagaaaatgc accatcaagg ttttttacgt
    38941 ggtagccaga ctgcttcaag attctttccg ctagatagct acgtaatccg ctatgacagc
    39001 tgacgatata ttcttgttgg ctgtctaatt catttaatcg gtcccgaagt tcattcaaag
    39061 ggatatgttt ggcttccttg aatttgccct tttccaattc ttctgctgtt cgcacatcta
    39121 ataaaatttt tccttttgct agttctgtcg gcaattcatg ccattgtacg gtttcactaa
    39181 gcccttctgc aatgttcatt gctgcatatc ctagcatgtt tactggatct ttggctgagc
    39241 caaatggcgg tgcatacgtc aattctaatt ccggtaaatc gaagatcgtc aaatgccctt
    39301 tgattgctgt tgctaaaata tcgatccgtt tatccacacc ttttgcccca acaccttgtg
    39361 caccataaat ctcgccagtc tctggatgga agatcaactt cagtaaaata tctgttgctt
    39421 ctggataata gcttgcatga tcttttcctg atacatgaat gacttcaaaa gacagttcgt
    39481 tttctttggc tgttctttca cttaaaccgg tggatgcggc agtcattcca aacgttcgta
    39541 taattgctgt tccaataccg ccttgatttc ttcgagaaat tccggaaatc gtgtccgcaa
    39601 cttgtctacc ttgacgattg gctggtgaag caagagaaat aagtgcatct tttccagtga
    39661 tttgctgttt tacaacgata gcatccccca ccgcataaat atcaggaata ttcgtttgat
    39721 aacgttcgtc tactaggata cccccgcgta tgcctaattc gattccagcg gtcactgcta
    39781 gctggttatc aggacgaaca ccaatggata aaataactaa atcagcaggg atggtacgcc
    39841 catcatccag tcgcaatcgt ttcccgtggt cttcaaatcc agcgacagca tgagaagtaa
    39901 tcacttctac tccttgatga gacaattctt tttctataaa agctgccatt tcttcatcca
    39961 gtgttggaag aatatgtggt gcttgttcga tcaccatgac ttctaaacct cttcttttta
    40021 ggttttctgc catttccaat ccgatgaatc ctgcaccaac gatcacggca cgctttggct
    40081 gtttttctaa tgcatgcatc actttatcga tatctggtac atttctaata gaaaaaacat
    40141 tgtcggcttc tgttatccct ggaatcgatg gaacaactgg ttttgcacca ggagataaaa
    40201 ccaatgcatc gtactgttca atgtgttttt gaccctcatg tacgacttct accgttttgt
    40261 tttcgggaaa gatggctgtc acttcatgat ttggacgcac atctaaacaa aaacgagcgg
    40321 ataatgattc tggcgtttgg acaagaagat tttcccgttc actgatttct cccgaaagat
    40381 aataaggcaa gccgcaattt gcaaaagaaa catacggtcc tttttcaaaa acaacgattt
    40441 ctgcatcttc cattaatcgg cgaagccgtg tagcagcaga cattccacct gctacacctc
    40501 cgacaataac gattttcatc ttatttccct cctactgttc gatcaaacca ttgattcatg
    40561 ccaccacgta cattcactac atcataacca gatttcttta attctttagc tgcttgttta
    40621 ctcctcatcc ctgattgaca aatcacatag acggtctttt ctttgtctcc atcatatctg
    40681 tttatacttt gtaatggaac atttttagct ccttttatat gcccgccccg gtattctgca
    40741 ggtgttctaa catcaagtaa cgctggattt tccaaaagct tttcctttaa ttctgggact
    40801 gttatcgatt ttattgattg aaatagcaaa ttcattttct gcacctcatt tacattttta
    40861 taaatacctc atggggtata ttaaacagga gctttattaa tatgtcaacc agaatgactc
    40921 ttcatttttt tcactacttt ttatatttgc ataaaatacc gataaggggt attatctaat
    40981 tataaaaata gaggagaatg tgttatggag attgataata aaaatatcct gaaccgtttg
    41041 aaacgtacag agggacaaat tcgtggtatc caaaaaatga tcgaagacga aaaagaatgt
    41101 atggatgtca tcactcaatt aagcgctgtt cgttctagta ttgatcgcgt aatgggcatg
    41161 atcgttgcag ataatctgaa aaattgcttt gagaaacctg atagtaatcc agaagaacaa
    41221 gcggctaaac tagaacaagc gatcaagatg attattaaaa agtaaaggaa tgatttcaat
    41281 gaaagtcgtt ttccatattg atgaattaga aaaatggtca gaaacaggga aaaacgtaaa
    41341 aaacctgata aaagcttctc cagaaacgac gattgtcgta tctgtaaatg gcatcgcgat
    41401 taccggttat ctagactctg ccaatgcaga attcttagat ttgcaaggag tcgtttttca
    41461 cgcttgcgcc aatgctatgc gtgctaatca tatttcagaa agttctttac ctgaacaagt
    41521 aatcgttgta ccagcaggtg tccttgattt agttgaactg caatcccaag gttatgctta
    41581 tatcaagcct tagtcagtag aggttgcgac agaagtgatc agcttcaaga aatttcggct
    41641 tatttttcga agaagctact tctggaaaac cgtgaatcaa aggttgtgaa aacgctgtcc
    41701 tgcatcaagt aataagaaca gccaaacaaa aatagcttct catatttttc gtttggttgg
    41761 gcttattacc gcagatgcaa gcttttgaac accgtttaag gaagaggttg tgaaatcagc
    41821 ggtttgacct aagtattaga gaaaaaaacg ggaaaatagc tcctcatatt ttgccgtttt
    41881 ttgagctaat accgaaggtc agctgattga acaccgttta aggaagagat tgtgaaaaag
    41941 tcgcttagtt tcgagtatta agaaaaattt tgtgaaaatg gatttctaca tttttgcata
    42001 aatttggctt aataccgaga aactggcttt tgaataccgt ttaaggaaga ggttgtaaaa
    42061 tcagcggttt gacctgagta ttagagaaac aaacggaaaa atagctgctc atattttgcc
    42121 gttttttgag ctaataccga aggtcagctg attgaacacc gtttaccaag aggttgtgag
    42181 cctaccattt aactccgaat cacaagaaat aatttcaaaa acaacttctc ctgtttttgg
    42241 ttcggttggc ttattatcga gaagtagcta ctgggagtct atttatcaaa aaaaggaatg
    42301 cgacataggt cacacccctt ttttattttc tttgaaacat ctttcggtac tcgacagcat
    42361 acaagacaaa agattgtaaa agaccgtaag tgatgacggc aaaaatgact ctcacccaca
    42421 gcgttggtaa ttctgggaaa agcagcaaaa ggatcatgcc aacatagatg acagcagtcg
    42481 ctactttgcc ataccacttc gctccactta atttgatatt tttagatagc ccgattaatc
    42541 cagctacaaa cataaagcct tcttttatca agaatagacc aaacaacagc caaagccacg
    42601 gtcgatacca tgccatagac aaaatcagaa aaagttgtgt caatttatct gcaaacggat
    42661 caagcacctt ccctaagtct gttacctgat tatatctccg agcaatgacc ccgtctagat
    42721 aatcagacaa acctgagaca acaatgaccg ctcctgctat ataaaatgac tgtctcagca
    42781 caaaataaag ataaatcggc agcaaaaaaa tacggaatat cgataaaaga ttcggaatcg
    42841 tttgtatttc tttacgccag tctgtgctta atttcatttt atcgccctac ctcctcagca
    42901 ctcttttctt tttattttag cttacacggg gaataaaacc aatgatttca ctgtttttat
    42961 ttttctttac agacactgat attatgagct aatttgagat aatcacttgc tgttttcatc
    43021 gtttactctt ctttcttcct gtcgtttgcg catttctttt actagtactt tatgagcttt
    43081 ttttgatcct cgctctaggt cacgctgccg tttacgtgtt ttataatcga taaacagact
    43141 gtctaaatcg taacctgtcg ggtacagatc ttctgctgaa cgcaccagac gaacacgctg
    43201 acgaggcacg tggattattt ttttgtctaa atatacatca atcgtatctt cacctatatc
    43261 ttcataaact aacgcttctt tttggtattc attgacaaat atccgatcac cttttgcaaa
    43321 gagctgacgt tcttttttat tctccttcct atttgtaact gctgtcttag gaagaaattc
    43381 ttttttctgt gtccgatagg ctttttccgc caagtaacgc tctgcttgat ggatcaattt
    43441 catcgacata tccattttat gagcaatcca caaagcttgg ctttctcctg tttcttccaa
    43501 cccgcaactg atatttagga cgaagtgctt cccgatcgaa agccatagca gccggcacaa
    43561 aatcttcatg atctccggcg aatttcttga tttctccata atgggtcgtg gcaatgatca
    43621 atgccccttg ctcatacata gattccatga ttgcgatcgc tagtgcagcc ccttcatttg
    43681 gctctgttcc actgccaatc tcatctaaaa gtaccaacgt attccttttt atctttttca
    43741 aaatagcagc gatgttttgc atatgaccag aaaatgtact caacgcattt tctaaatttt
    43801 ggtggtcacc gacatcgacg aaaatctcat caaagacagc aagctctgtc ccttcttttg
    43861 ccggaacttg cataccgaac atcgccatca aagtcaataa accgactgtc ttcaacacga
    43921 ctgttttgcc tccggcattt gctccggtga taatcaagcc tcgatagtct ttaccgattt
    43981 caacatccaa tggtaccgca tgctcaggta aaaatggatg tctgccttgc ttgataatga
    44041 tatgttccga tttattgatt ctaggtgtgc ttccattgat ttctcggcta aattttgccc
    44101 gagcaaagat gatatctaac accgtgatcg tttcgatcaa taaatcgatc acttcttcgt
    44161 tttctgcgat agcaccagtc aatgccgcca ggacttgata ttcttcactg atttcttcag
    44221 cttttaacaa ctgatagtgt tcattcaatt tagaaatcac agttggttca ataaaaaccg
    44281 tcgttctttt atttgattca tcgataatcg ttccatctat tttattttta tagctggctt
    44341 tgataggaat cgtatagtat tcgccttttt gaacaatcat tgcttcttgg atcatttctt
    44401 tgtttttcgg atgacgcaag aatttcagta attttgactg gatttctttt tcgattagtt
    44461 gtaattgttt gcgtacttta cgcaaattac gtgacgcgtc gtcactgact ttattatttt
    44521 ttattttctg gtcaatcaac tcttctacat ttatcaaatc aggaagatgt ttgctataag
    44581 caaacaacaa gggtgtctgg tattgattct tatcaaaaaa ctttgtgatc atccgactgc
    44641 ttctaagaaa atccgcatat tcgatcaaat cggttggctg cagaatcaac ccttttttga
    44701 cttgttctgt cagtgcatcg atcctcggca accccataaa tggaacatgc tgactgcttt
    44761 ctaagatcaa gcgtgcttct cttgtttctt cttgacgatc caagacagtt tgtaggtttg
    44821 tcgagaccgt catatcgctg attcgttttt tgctatagtt tccaattgct cttgcttgga
    44881 tttccttttt gatccgatca aattgtaatt gactaatcat ttcgttgtcc atattctctc
    44941 cttttcttga agagatacct gtcccaaaat aaataagggc ctagagataa ataaaaggat
    45001 agaacacagc ttaaaaaagt catgtcctat ccttattaga atacaaagat attgttttcc
    45061 tgacaggtac cgtttcataa gcacaccaaa taaactttgt ttattggcta ttcgacttac
    45121 tgattagata ccagctacac tcacaaaaca taccccattc ttctaggtct tatttatttt
    45181 ccacttaact atagcaagac acattttggt tgtcaaactt tagtatgttt tatagattta
    45241 caccattaat gaatagacac ctaccgcgat aattgctccg atcattggac ctgcgattgg
    45301 tacccatgaa tatgcccaat ctgaagttcc tttattagct attggcaata ccgcatgtgc
    45361 taatcgagga ccaaagtccc gagcagggtt gattgcatat cctgttggcc ctcctaatga
    45421 aagaccgatg gctaagatca atccacctac agcgaatacg ttcgttccag gtgcaaattc
    45481 gttttgtcca aaagctagca acccaagaac taatacaaat gtaccaatta attctgtgat
    45541 cacatttgct ggataattcc gtatagcagg acctgttgca aacgttccta aaatcgcgct
    45601 ttcatctttc gttgcattcc aatgtggcaa ataagaaagc caaacaagaa tggcccctgc
    45661 aaaagctcct aaaacttgcg caatgatgaa aggaacgaca agattccaac taattgcccc
    45721 tgtcatcgcc atagctagag agactgcagg attcaaatga gctgggccca tgaatccaga
    45781 aatatagaca gccattgtta cagcgagtcc ccaaccaaat gcgatgacaa tccagccaga
    45841 agcctgtgct ttacttttgt ttaaattcac agccgcacac acaccatctc caagcaaaac
    45901 taggatcagt gtcccaataa actcccccat gatttgagtc atatcactgt tcatttattt
    45961 ctcccccttt agttcccgca gatctgattc tgcaatcaat gcttctaaac gtttagtctg
    46021 ttgcgccttc tcctcttctg tccattcaaa atatccagca attgcatcga tcacaggttg
    46081 cttgatctca tcaagctgat ctcgttcaaa caacagatga tttgtacgac gaatgagata
    46141 atcgcctggg gccaaaacca tttcttcttc taaaccataa cgtaaccgag ctgactcagc
    46201 gagactcaaa ccaggataag gtgccatttc ttttgctaat tcaaagatac gtcgggcatt
    46261 agtcccgtaa aaatcagcga tataagtagc atcttcttcc tctaaaccgg ctgctactcc
    46321 ttcttttgct aattctgtca ctgtttcttc taatttagtt ggatcgaagt ttccacctga
    46381 aatctgatat tttttagagt cgatttcttt cgtctctatt ccgtattctt cttttaataa
    46441 ttggcgtatc aatcgcaaag ctccttctgc catcttacgg taatcggtga ttttcccacc
    46501 agataaagtc agcaaaccat ctggttctct ttctaaagaa ctacctctgg aaatcgtaga
    46561 aggtgctttt tcatcacggc tgttttccaa atggttcaac acgtcttcta cttcagcacg
    46621 agaaactttg ttttccttat attcacttac tgtatcgaca actttattga agctcttgtc
    46681 tgaaatcgat ccattatctc caccattgta atcagaacca gaattaccaa tcaacagtgg
    46741 acgaagtcct gcccagcttg cttcgatatc attcaatgtg atatttgctt ctggatagcg
    46801 atgattgatc acatccaata gataatctac atcttcttgt gtgactttcg gatccgtaaa
    46861 atctccttgg taatccgtat ctgtcgtacc aaagtaagtc ttgttttctc ttggaatagc
    46921 aaaaaccatc cgcccatctt gctttcctgt atcgaagtat gtgggttgcg gtacaggcag
    46981 ttttttcgca tctacaacta aatggatccc tttagttgga cgcattttag gagagactgg
    47041 acgcgtaaaa ttcaagtttc gtactttatc tacccaagga ccactcgtat tgatcactaa
    47101 ttttgctttg atttcgatca cttcatctgt cagcaggtca cgagctttga cgccaacgat
    47161 ttgatcgcca tcatataaaa agccaaccgc tttcatttta cttactagat aagccccatc
    47221 ttcggcagcc tttttgatat tatcaatcac taaacgggca tcattgttgc ggaaatctag
    47281 atagacaccc gcgcctttta gcccttcttt tttcaaaaac ggttctcttt ccaatacttc
    47341 ttctggtgtc agcgtataat tctcatattt ggttcctgtc acatttgcca gtttgtcata
    47401 aaggtccatt gctactttga ccgagaacat attgaaggtt gttgctcctt cgccctcata
    47461 gattggcaaa agcattggat ctggttttgg gatgtgtggg gcaatacttt gtacgactgc
    47521 acgttcacca actgtgtcag ctactacttc cacatcaaat gtcttcagat aacgaatacc
    47581 gccatgaaca agtttggtcg agcgagagga agtcccttct gcaaaatcct gcatttcgat
    47641 caatcctgtt ttgattcctg atgctgctga ctggactgcc acaccggcac cagtgattcc
    47701 gccaccgatg atcaacagat ccaattcttc ttgctgcatt ttttgaatgc tatcttgtct
    47761 tgtcttgttt gaaaacatat ggatttcctc cttattcaaa tgcttgggta gcttttactg
    47821 cttttttcca accgttgtaa agtttttctc ggcgctcttc ctccatttga acttcaaata
    47881 gcttgccagc ttcataaaat tcgcggatct cgtctgtatc tttccaataa ccgacagcta
    47941 atcctgctaa aaatgctgcc cctagcgccg ttgtttccaa gttttctgct cgttggatcg
    48001 gtacattcaa gatatctgtt tggaattgca tcagatattc attgtttgct gcaccgccat
    48061 ctactttcaa tacaggaatc ttgattccag tgtcatcttg catcgtatcg atgatatctc
    48121 tcacttgata agcaatcgac tgtaaagtag ctttaatgat atcttctttt gtcgtaccac
    48181 gtgtcaagcc aaacatagcc cctcgtgctg cctgatccca ataaggagca cctagcccaa
    48241 cgaatgcagg aacaacataa acctcatctt cgcttgtaga gcgtttcgct gcgtcttctg
    48301 aatcgctagc tttttgcaac atttgaagtc catctctcag ccattgaatc gaagaaccag
    48361 ccacaaaaat acttccttct aaagcatagt aaacctttcc atttatgccg taaccaattg
    48421 tcgtcaataa attatttttg gataattgcg gtttttcacc ggtattcatg acaataaatg
    48481 aacctgtacc ataagtattc ttgaccatgc ctggttcgaa tgccatttgt ccgaataatg
    48541 cggcttgctg gtctcctgcc atccctgaaa ttggtgcttc gcttccataa aaatgataac
    48601 cttgcgtata accataaact tctgagttag aagtgacttt tggtaacatc actcgaggaa
    48661 tatttagtaa atctaaaatc tcctgatccc aatctagctg atggatattg aacaacatcg
    48721 tccgactggc attcgagtaa tcagtaacat gtgcttgtcc atcggtcagt ttccatacta
    48781 accaagaatc gatcgttcca aacatcaatt cgcctttttc agctcgttct tgcgcgcctt
    48841 ctacatgatc aagaatccag cgtatcttcg ttgctgagaa ataggcatcg atcactaacc
    48901 ctgttttttc gtggaaaaat tcttgatagc cttcattttt taagttatct gcaattccag
    48961 ctgactgtct ggattgccaa acaactgcat gatagattgg acgtcctgta tctttttccc
    49021 atattactgt tgtttcacgc tggttcgtta tgccaatccc agcaatctga tttggtttga
    49081 tccctgattc gatgaacgct ccggcaataa ctgactgtac agaattccag atttcatttg
    49141 catcatgttc cacccaactt tcttgcggga aatattgcgt gaactctttt tgagaactgc
    49201 cgatgtgtct tcctttcttg tcaaagataa ttgctcgtga gctagttgta ccttggtcaa
    49261 tcgccatgat atacgttgat tctgtcattg tgattccctc cattatatgc aaacgctttc
    49321 tttaactact cttatcatac tactgtttta aaaaaagaaa ctgtcaaaat tttattcttt
    49381 ttttcttttt ttgacagttt tttattatga agctattttt taatcaattc ttttcttttt
    49441 tcagcgtctc tattcttctt ttcaatcgaa taatgtcgta aggtgacgca aattctgaca
    49501 gataatattc acactgtttt ttgtttctct ggcaaaatgt gatcaccaaa tcatattctt
    49561 taccttcttc ataacttcca atctcaatac cgccgattcc cctcagttct ctgatcagat
    49621 attgttgaaa agcaatacga taaatcggca gactttctaa atcgattcca atcactactg
    49681 gttttgcaat ataaaaatcg atcatcaaaa gaacattggc atactggatc atcaggtaac
    49741 taagctcact atcttcagct cttttcctcg gcaattgctg caccgctgtt tcctgtaatt
    49801 tcgccagtaa ctgtgttaag gaatgcccga gcattttctg ctgctgttcc aaaagccgat
    49861 cacgctcata gacttcgatc tttccaacaa agaaaaacca ttcattgttg atctgggaaa
    49921 tttggtagcc tactgccttt tcttctttga ttttcaaacg acgaggacga taatgccata
    49981 acatcgtttc ccgaatgtaa gtatctaaaa cagcggttgg taactttttg ctccgtgtca
    50041 aatcatactg ataaaatatt tcttcgtcta ctatcgaaaa agaaacaaaa aagctgtaaa
    50101 acatcattgt ttcgtataca ttcagttctg ctgctgttcg actaagatgc atcacgatga
    50161 ttggatcgat tgcttgataa agccggtccg actgatagag taatttcttt tctttcaaag
    50221 ttgcgtacgt acttttttca ttcaatagtc tttttttcgt aatcccgagc cagcaagcaa
    50281 tctgtgcttc tgctgatgcc gtaaacgttg tttctaatac acggtccaat cctagaatga
    50341 acggtctttt ttctggtgta ttttgcaaaa aaagcggtcg ctgatcttcc gggatatatt
    50401 ggaatagttc ataataaaaa tatcgtatct gtagctcttc tccgtataat tgaccgtttt
    50461 tgatttgtaa tccaaattcc tctaagagct ggttcaattc tttgatcttt cgaaaaacag
    50521 aagactcact gatattaaac gctgtcgcta atcgaacgat ggatacttgc tgatgttcta
    50581 ataaatagac gagcatctta aacttcaagc tttcctgcaa taaaaacaat agaatttttt
    50641 ccaaacttac atcttcgtcc aacacaagca gcgcctgata ctcatttcgc tgtacttcta
    50701 cttttttttc catcattcgg ccaatcaatt caatatcttc caaatattga tcaaacgagg
    50761 cttttgacag ttggacatgc tctctcaaac cattgataga ggctgttccc ccttgcagaa
    50821 caaggtttcg caaaatcagg atctgtaact gctcttttct ttctaataat gcttcaatct
    50881 tcataggcag tattcgccac ctttgaccac accatatctg gcacacggta ttctggctgg
    50941 aaaaatagct catgttcttc taactgttca aacgtccatc cttcttctac tgcaattgtc
    51001 agttggtcaa gaaggtggaa catctctttt ttgctttgga gctgtgctcc aagaatcttt
    51061 ttttcagaat caaatagaaa tttgagttta actttgcttt gatttattgc tgtaagcttg
    51121 tagtctacgt atcctgtttc aattttttgg ggataaaaaa tgctctcttc ttctgtcaaa
    51181 cctacgcttc ctaagaaata gccaaaccac tgattgccga ctggacgata ggttccctga
    51241 tcctttgtct gtgagccact aattgtcttg ctgacatttc gtgctgtacg gacagcgtta
    51301 tttactagag aaacatacat tttttcattt gttggacgaa aagttacttg gatcgcatcg
    51361 ccaatcgcat aaacgtcttt ttgagacgtt tgcaagtagt catctaccca gatcgttcca
    51421 tcatcattca atgttaattg ttcttcccac atctgattgt cgggacgaga atgattagcc
    51481 agcaaaacaa gatcatagtt ctcctttctt ttttccgtct ctacaatagc ggtttcattt
    51541 tcggtcaaag acacaacttg ttcttctaaa aaaagtgaaa gcccttgatt tttcatttcc
    51601 tttactaacg gttctgtcat ttcaggatct agataacgaa aaagaattga ctttcggctt
    51661 tcgtaaagat ggatttgttt ttttcttgat gccaaccctt cagctatttc gattcctgct
    51721 tgtcctgcac caataattgc aattttcttt gcattcatga tcttttgctg aagagccgtt
    51781 acgttttgta tctttttaac tgggtgaata agcgttgatt ctgcagaaat atttcgaaac
    51841 ttttgatttg aaccagtcgc tagaatcaaa cgatcaaaat ccaatttttt tcctcctgct
    51901 aaaacgactt ttttttcttt caatcctatt actgtctttt ctgtgtaaac atggattcga
    51961 tagcggtcag tcagttcttc tttcgtgatc caagaaagtt gtttttcact ggtaaccttt
    52021 ccttttaata tcaaattgaa cccgctggga atccatccta acttcgattg cttttcaatc
    52081 aaatatattt cacttgttgg catcaattgg cgaagataaa tagccgcatg aatccctgca
    52141 aacgacccgc cgacaattac aatgttcatc tgcattcctc tttcttataa ggtgttctac
    52201 tgctaacttc tcaatcagaa aacacagtat tcataactcg ctttcaacct tatgatacat
    52261 agcgatgcag cagaatcaac cctctccatc ataccgtgtt ctaggtctgc ttctcaataa
    52321 tgtactagtg gacctaattg aagagtatca tttctgaaga gatgtttcaa aaaatgtact
    52381 cttataaaag aaaaaaactc gccttttacg tacctctgtc caaataggaa acagaaaaga
    52441 acgaaaagac gagttttagc gtgtgtaatg taatagttag aatagacaca tcatttattt
    52501 ttaattcttt aatgcttcaa caactgcttc gcctaattga tgagcagatt gaggattttg
    52561 ccctgtaaga agccgcccat caatttgaac cacttctgaa aaagctgctc cagactgata
    52621 gtttgctcct ttttctttca aagcatcttc tgctaagaat ggtacttcat tcgttgtacc
    52681 atttgcttcc tcttcttcat tactgaaccc agtcactgta cgtccagcta aaatagattt
    52741 tccagactca tctgtaactg gcaacaatcc tacaacaccg tgacaaacag ctgagaccag
    52801 cccttcattt cgatagattt gtgaagcgac tttcccaaga tctattgctt ctggaaaatc
    52861 ccacattgtt ccgtggccac cagcataata aaccgctgca taatcatttg catccacatc
    52921 atcaggacgt aaggtatttc ccaaggcccg atttctgaaa tcttcatctt cataataggc
    52981 ccaatcgatt tcatccatat tcaaaacact ttgcggttct aaaggtacat atccgccttt
    53041 aggactgaca aaatctgcat cgatcccatt ttttactaat acatcataaa aatgagtcag
    53101 ttcacttaac cacaaacctg taggacgctc gatcttttcg tacttttcta catttgttaa
    53161 tacgatcaat actttcattt tcccatcctc tttctataaa aattgcgtta ttgataacgt
    53221 gctttcaaga aattatataa tgggcttggc aaataaagct ctttatatgc tttttcaaaa
    53281 ggtttcgtta caaattcatc ctcacggttt tccaataatt tctctgccca gtcaggatcg
    53341 acgatcattt gctgtccaat tgctgcaagt tctgcatatt tcaatacctg ctctacatct
    53401 tcgcgattgc ggatcccacc gacaccaact aaagggatct ttccttgaat cgtgttatgg
    53461 accacttcaa gaatcgattt atcgttgtat ttatcagaac gagctattcg atcatacata
    53521 tttaatgaaa catgcagata atctagtttt gactcacgta atcgttcaag aagccagatc
    53581 gtgtcttcaa aacggatacc tggtgtttca tattcttctg gtgagaaacg ataccctacg
    53641 atgaatggtt ttttagcata ttgttcaacc gctgagaaaa ccgttgttaa taattcttca
    53701 ataaaacgat aacgattttc caagctaccg ccccattgat cctctcgtct attcgaatgc
    53761 ggagagaaaa attgttggat caaatacgta tttgctccat gcaactcgat tccatcaaat
    53821 cctgattcaa tcgctctacg tgtggctttg ccaaatgctt ggattgtttc aacgatttct
    53881 tcttcactca ttgctcgtgg tgtttccgca tcaggacgtt ttgctgcaac tgcacttgca
    53941 gatacaggct gttctccaga taaagttgct cgacttgtca ttcgtccacc gtggaaaatc
    54001 tgaataatcg cttttgcgcc ttctccttgg attgctttcg ctagctcact taatcgagga
    54061 atcatttcat catgagcgat gctgagttca cctggccagc cttttccgat atcttggaca
    54121 tttgcagcac cagtaataac agcaccaaga cctttagaac gttgtttata ataagtgatc
    54181 tcatcttcgg tgatcactcc attgaaaaag ctgagttgtg tcgtcatagg cgacagcatc
    54241 aatcggttct tcaattgaac tcctgaaggt aaagtaattg attgatcaaa ttgtgacatt
    54301 gtcattcctc ccataattcg ctctgattaa cctatcgaga atcatctatc attaaaccac
    54361 tcgattagtt gtacatgcaa ctaatttgct taaaaaattt tatttttttt gtaacttatc
    54421 tgttgcatca ttcattgtct gggctaattc tttacttgct tcatttccca aaactgcttt
    54481 gtatgactga tgaagttctt cccagctacc atcgacttcc ttagcaaatt ggcgtccttg
    54541 ttctgtaaga taaactaatg acaagcgacc ttcgctaact gttttgacgt atcctttata
    54601 ttctaatttt tcaacaaaac gagcaatcgt tgatggggcg gaatagagca tttgtgcaat
    54661 atctttttgt ggtattccat ctttttcttt taatatcaat aaaataaaac cataagttgg
    54721 tgccagacct gtccttctaa acgcttcatc agctaattta ttcaacatgc gatctagctt
    54781 tttcacgcta aagaaaagac attcatctaa cgctttttca attggctttt ccatttcatc
    54841 ccctccattg gcgtacatat catagtatga tttttatttt ttgtcaaaaa acacggaata
    54901 atgtccgcct cctctgtcta gatttgaaaa aaagaagtag ccatcttcaa agaatttcgg
    54961 cttgttttcg acaaaactcc ttctggaaca ccgtgaatca gaggttgtga aaaagtcgtt
    55021 tagttttgag tatgaagaaa aattttgtga aaatggcttt ccacattttt gcataaattt
    55081 ggcttaatac cgaaaaactg gcttttgaac accgtttata tcagaggttg tgaaaaagcc
    55141 gtcctgcatc aagtaataag aacagccaaa caaaaatagt tcctcatatt ttgtcgtttt
    55201 ttgagctaat gccgatggtc agctgattgt acaccgttta ttgagaggtc gtgagcctgc
    55261 cgttgaactc cgagtcacaa ggagcaattt caaaaaacag cttctcatgt tttatgacta
    55321 tggtgacttg tgatcgagga gttggcagga gaatactgtt tattcgtaaa gaaggggctg
    55381 tgacaagact tttgtcacag tcccttattt ccttttatta taggatttcg ccatttgatt
    55441 ggatgacttg tctgtaccaa tcaaatgatt ttttctttaa ccgtttcttt gtgccattcc
    55501 cttcgtcatc ttgatcaaca tagatatatc cataacgttt tgacatttgt gaagtagaag
    55561 cgctgacgat atcaatgcag ccccacgacg tataaccaaa taaatctact ccatctttga
    55621 tagcttcctt catctgctca atatgctgct tcaaatagtc aatgcggtaa tcgtcttgaa
    55681 cggttccatc ttcttctact ttgtctatag ctccgagtcc gttttcagct atgaacagtg
    55741 gtttttgata cctatcatat aattgattca aagcaattct caaaccctta ggatcaatct
    55801 gccagcccca ttcacttgat ggaagatacg gatttttaat tcctccagtt attaagtttc
    55861 cttggacccc ttcccaattt tctggatgag cactgactgc actagacatg tagtagctaa
    55921 aagaaacaaa atcaacaggg taggctgcta agatttcttc atcacctact tctattttta
    55981 agttgacacc tttttcttca aacattcgtt gcgtatacgc tggataatat cctcttgctt
    56041 gaacatcact aaagaacaaa gaagttcttt gctgctcaat tgttttttga atatcatccg
    56101 gatcacaaga atacggaaca agaagctgat agctgatcat acaaccgact tgtgaacctt
    56161 tgataatttc atgacaagct tttgtagcta aagcacttgc tataaactga tggtgtgcac
    56221 cttggtattt cgcttgttcc aaatggggat ggttttcttc aattactcct acgctaacaa
    56281 aagggtgatg ttttacacag ttgatctcat tgaaagtcat ccaatatttt actttatttt
    56341 tatagcgttt gaatactgtt tcagcgaaac gaacgtaaaa ctgaataagc tttcgattag
    56401 gccatccacc atattctgta accaaatata acggcatttc ataatgggaa agagaaacga
    56461 ctggctcaat cccatatttt agacattcgt caaacacttg atcataaaaa aataatcccg
    56521 cttcattggg tgtttcttca tcaccatgag gaaaaattct tgtccatgcg atagacatcc
    56581 gatagcattt aaaacccatt tcagcaaata aacggatgtc ttctttaaag tgatgataga
    56641 aatcatttcc gtgtctttta ggataataat acttgctgtt gggatcctgc gccgctttta
    56701 cttgctgatg cgtcatcata tgccattgat ctgtccattt ttctttaggt aaatcgctgt
    56761 cgaatgtata cacatcagac acagataatc ctttttcatc tacatcccat gcaccttcac
    56821 attgattggc cgctgtcgct ccgccccata aaaatccttc tggaaatttt ttcatatcga
    56881 tccccctaaa cttgctagtt ttcttgtttg attatttttc ttatgactag taatgatatt
    56941 tttgaatcta ctactatttg taacaataac cattgtggtc ggatcatatc cctctttgat
    57001 taattcttgc aaatctactt ccatcaataa atcgccttta cgtacttttt ttccatcaga
    57061 tactgcactt tgaaagtatt tgccatttaa attcactgta tcaataccga tatggatcag
    57121 tatctctgct ccttcttcac tgactacccc aattgcatgt ttcgttggaa aaactgttga
    57181 aacttccccg tttacagaac tgtagatttt tccgtccgtt ggaatgatcg caaacccttc
    57241 tcctaaagat ccactagcaa atgttggatc gtttacttca gataaatcaa ttatttcacc
    57301 tgctgcagga gtacttaaca ctatatcctt tgaggattct tcttcgattt catccttgta
    57361 gccgaaaaga aaagttagca tacaggaact gatcatcgct aagaaataac tagcaactag
    57421 ccaaacaaat ccttcaccaa tataaatcgg gaaagacaaa atacttcttg tagcaactgc
    57481 caaagcaccg gctcctgcgg caccagctac tccaccaaat atagctccac atatacaagc
    57541 aatgtaaaat ggtcgtttat atttaagagt cacaccataa acagcaggtt cagtgattcc
    57601 aaataatgct gtgataaatg cagataaaga taaacttttt actttcttat ttttcgtttt
    57661 caaaaatacc ccaagtactg ctcctgcttg cgcagctacg gcagtcatac atgctggacc
    57721 tagcgtatca cgaccgtaga aagaaagatt gttggtcatt actggtacaa gtccccaatg
    57781 taacccaaaa atcactaaca cttgccaaaa tccgccgata acagcaccag ataaaacagg
    57841 gctaaagtta taaacagcta aatatccagc tgcaatcagc tgacttgcat aatctgcaat
    57901 tggacctaca actaataaaa taattgggac catcacgatg atacaaatga atggtgtcaa
    57961 taaatttcga atactttcgt gcaagctttt gcgaatctta ggctcaatat aagaaagaac
    58021 ccatacagct aaaattgctg gaataaccgt acttgtatac cttgctagaa tcacgggcat
    58081 ccctagaaat cgcaaggtta tgctatcact atatgcactg acaatcgtag gataaacgag
    58141 agctgctgca ataaccatag cgatgaaacg atctgtattg aacttttttg cagcagtata
    58201 tgccaaaaat ataggcaaga aatagaaaaa tgcatcagct gctgcattca aaatgatata
    58261 agttcctgat tcagtagtta ataaattcaa actcgtacat aaggcgagta ctcctttgat
    58321 caaaccactt cctgccaaga cgcctaaagt cggggcaaaa acagcggcga tcatgtctat
    58381 aaaagagttt aaaatgcctt ttttctcagt tcctctcttt ccactagatg catcatcttc
    58441 tagtttcatt tgtttggata atacgtcata cacttcattt actgcatttc ctactacgac
    58501 ttgaaacatt cctccagctt cgactacagt gatcacacct tctagttgct ctaccttctc
    58561 cttatctgcc ttcttattat cttttagggt aaagcgtaac cttgttgcac aatggtaaac
    58621 attgctgaca ttttcttcgc ctccgacaaa tcggacaata tctttcgcta attgtgaata
    58681 gtccattttt acttccccct tgttaattaa tgccgtagca atccttctta caagataagt
    58741 atagttctta gaaaacggtt tctccattca attagtaccc cttctaatag cgaacgaaac
    58801 tgtacaatag tgtgtatggt ttacttagcc gagcaaatca ctcactgctt gaaagaaaac
    58861 aagtatatcg tttctcttat agtcaaagga gacaaaaaaa acacgcttga tcttcctttg
    58921 ctgatgtata agtggtatct caagctgata ctctgtgatt tttgtttcta cttggctttt
    58981 gataagacag cacaacaaag tctcggcatt taacggaagc ataactaggt cagaactagg
    59041 agagattagt tgctgaatgg aatctatctt tttatggatt tttatttgat tttcttcttt
    59101 gtagtaatga tcaagcagtt ttgttttctt tttttcttca actatggtca gcttttcacg
    59161 caaaatctga taaatctccc aagattcaaa ctcatctaga acactaggta gataaatcaa
    59221 atcatcccac tcaaaaataa gctcttgctc agtagtcaaa attgcatcat attccgttat
    59281 tttgtttgat tgatttttga aaagatacac tggttctatc cggcattctt tgatccacat
    59341 gttcatactt tgttgaatct gtttttttag tgtattcaaa atactaattg gctggttact
    59401 aacaatcagt atctcccctt gttttcgaaa aggattcaac gcttcggcaa gatacaaaac
    59461 aaaataagcg ctttcagcta aattgggacg taattgaaaa tgtattggga agaaacgccg
    59521 aattaaataa atttctaaag gataacggga gatgatcttt tgtacaaaat gattcatggt
    59581 attatgtccg gcatccatcc tcgttttcat ttgtttgata tgggttagca aaaattctgt
    59641 ttcatggaac aataacgaaa caggaagatc taaaaaacga ataatcgttt gctcaaatgc
    59701 tcttagattc ttctctattt ctttgttttt ttcatcatta atcatcaaat aatttaactc
    59761 taatagtcga ttttcaattg cttgtttttc ttgattggaa aaagaatagg gtagttctga
    59821 tgataacttt tttgtgaggg tctctaccat cggaataaat aatgtatacc tgtttgtttt
    59881 ttctaaaagt tcttctcttc gaagaatggt caaaacgaga taccgagaaa atcgtatgaa
    59941 gtcctctcct gaaacaatat aattatatga tataagaacc tcttttaatg tcttttggac
    60001 agtcggcatg atattggaaa aaattgtact gatttgttga ggaaaccttg cgtgttggat
    60061 caccgtttct gttccaacaa gagataagaa aattcttttt gaattttctt cagcaatgat
    60121 ttttagtcct tttgtcgacg aaacttccag ttctaattta ggattgcgct cgatccaacg
    60181 caaaatcgtt tttatttgta atgatacggc tgtttttgaa agaaagaaaa tgtctgctat
    60241 cttttgcata ctgacatacc ctttttgaaa caataagtac gtcacaatag ttgaagctcg
    60301 gaaatccatg ctggaataga ttttatgttt cgtcacctct tgtatgattt gctgtttagt
    60361 ttcagattca attgattcta aaaaataacc tgaacgttta tttgactgga taatgatttt
    60421 cttctcgtag atagcaagca tatttttgat ttcagtttgg atcgttttct tgttggtacc
    60481 taaagcttca gctaattctt cgcttgttat ccaatgattc ttatttctta atactacaag
    60541 aatttggagt tgtcgtttat ttaagtccat ttgcttacac ctcctctttg ttataaacat
    60601 acaggaaaaa cctctcaaat gacaatagtc acttgcagag gtttaaaaat catttgaaga
    60661 aagatctata ttcaaggttt ttaccattag actggataat ttgtttataa tattcaaaac
    60721 tatctttttt caatctccta aagcttccgc tcccatcatt ttgtctatcc acataaataa
    60781 agccatatcg cttcctcatt tcccctgttc ctgccgatac gatatcgatt ggtccccacc
    60841 ataagtaacc aatgatttgg caaccatctt ttattgcctc agcaatttcc tgaagatgta
    60901 tttttagata ctcacaacgt tttggatcgt ggattcgatt caattcatct ggtgcttcat
    60961 ctagtccaat gccattttca actatgaata atggtaattc ataacggtct gtcaattcat
    61021 tcatgacata acgaaaccct agaggatcaa ttggccaact ccaaggttcg ggagattttt
    61081 ccttcaaaaa gggattatcg aaaccatttg ctccgccagt atctacgcgc atttctgctt
    61141 cttttttata gacagcgcta cgataataac taaatgcaat ataatctgcc gtgttagctt
    61201 gcaagcactg ttcgtctcca tctaacatta ctggtgcaca gtcttcttcc ttccatgtcc
    61261 tgtaaatata agctggataa tgccctcggc acatgacatc ggagaaaaac catgaattgc
    61321 gtttaaattg cagtgaacca aatacattct ctggatcaca gtcatatgca taagtcgcta
    61381 atgcagaaaa gctacacata atacccatct tagcatttgg atcgattttc tttaataatt
    61441 gagtagcacg ggcgttcgct agaaacatat gatgacaggc ttgataaatc actttttttg
    61501 ttagtgtagc aatgggttca agtttatctc tagcagggaa tgtaaccaat ccagcagctg
    61561 cataaggcat acgaaaagca ttattgatct cattaaaggt catccaatat ttcactttcc
    61621 cttggtagcg ttcaaagacg gtctgcgcat aaaattcaaa aaagtcgatt aattttcgat
    61681 tttgccaccc cccatactct cctaccaatg ctaagggggt ttcataatga ctaagagtaa
    61741 ttactggctc gatatcatat cgatttaatg tattgattag tctgtcataa aatacgagac
    61801 cagcctcatt tggcttctgt tcgtctcctc ttggaaatat tcgtgcccat gagatgcttg
    61861 ttcgaaaagc ttttaaacct aactccttca gtaaacgaat atcctcttca aatcgatgat
    61921 aaaaatcaat cgcttcatga gaaagataat ggagtgattc gtctaaagca atctcccaaa
    61981 tctttttttc ttcattccac tgaatactag gatgctggtt catgatcccg ataagcgtat
    62041 ctgtcacatt aggtaatttg ccgtcttcca accatgcacc ttcacattga ttagcagcta
    62101 ctgctccgcc ccataaaaaa ttttctggaa atatttcctg atccataact atctctcctc
    62161 gctatcaaca atttcttact tgaagtatag ctcgattcat caaaacaaga tattctaact
    62221 atttcggcag aagagaagaa aaaaattgaa tgctactctt catttttaat atttatatat
    62281 aacaaataca taagacgatc cccgaaagaa aacactcgtt aaccatctaa gcaaacgatt
    62341 tattttactt ccaacacaaa tgcttcataa ggtcgtaaat caactttgcc gtctggtaac
    62401 tgtttcagag gataatttga cacaataacc cttaaagctt cacgtggaat agtgaacgtc
    62461 tgcttttcac tggacatatt acaaataacg agccattgct ggtcttcata tatgcgagaa
    62521 taggcaaaga catgctcagg cgtcttttcc actaattcat agtctcccca gacgatgatg
    62581 tcatgttttc tacgcaaatc gatcaatttc ttgtacatat aaaaaacaga atcttgatct
    62641 gctaacgctt cttctgcatt gatttcttta taatttggat tgactcgaag ccatggaatt
    62701 ccagtagtaa acccagcatg ttcacgggcg ttccattgca taggcgtcct agcattgtct
    62761 cttcctttcg ccttgattga ttccaagatt tcctcttttg taaatccaga agaaatcctt
    62821 tcgttataca tattgattgt ctcaatatct tttgcttccg cgatatcatc gattgggcaa
    62881 ttcgtcatgc ctaactcttc tccttgatag atataagggg tgcctttcat catatggagc
    62941 aagatagcaa acatcttggc actttctttt cgatacacat cgtcatttcc ccaacgagaa
    63001 acaattcgcg gaagatcgtg attattccaa aataaactat tccatccttc atcacctaaa
    63061 gatgtttgcc atttggataa tacttttttc agttcagaga tactcaaggg tttcaaatcc
    63121 catttgtctt tgccttcttg ctgatctaat cctatgtgtt cgaattggaa gaccatggat
    63181 aattcatttc ttttaggatt ggaataaagt ttagcgattt cggtagttgc tccccatgtt
    63241 tcgccaacag tcatcagatt tttgtcacca aaagttgctt gattcatttc ctgaagatac
    63301 tcatgcagtt taggtccatt acttgtgatt tctttatccg gttctttgcc aatcatatcg
    63361 atcacgtcca tacgaaagcc cccaatacct ttatcgatcc agaaattcat catttgataa
    63421 atctcttggc gaacctgttt atttttccaa ttcaaatcag gttgacgctt gctatacaag
    63481 tgcagaaaat attgccccgt tttttcatcc aactgccaag cagaaccact gaatattgag
    63541 cgcaatctat taggctcttt tccattgacc ggatcacgcc aaatataata gtcccgataa
    63601 ggattttctt tatttttacg ggcctcaatg aaccacggat gttcatcaga agtatgattc
    63661 accaccagat ccatgatgat acggatattt cttttctttg cttcttcaat cagttcttcc
    63721 atttcttcca tcgtaccgaa ttctgccatg attgcttgat aattactgat atcatatcca
    63781 ttgtcatcat tcggagactc gtatactgga gaaagccaaa ttgcatcaat acctaaatac
    63841 gccagataat ccaacctgga aataatcccc cgcaaatctc caataccatc ttgatttgaa
    63901 tcttgaaaac ttcttggata gatttgataa acaactgaat ggtgccacca tttttgttcc
    63961 atgattttcc tcctataaat ggatgtttct attttttgct taatcattta ttttagtctc
    64021 tctcactaaa aattgtaacg ctttcaaata gctattgcac cttgttatcg gtaacagaat
    64081 aaaacaaaaa aacagctgag gaaattccct caactgtttt ttgaaaggat tgatttatgc
    64141 agggaagaat gctgatttca caacttcttt ataaacggtg ttcactcagc tgtcccttgg
    64201 tattagctca aaaaacggca aaatataaga aactattttt tcgttttttt ctctaatact
    64261 caggccagaa cgctgatttc acaacctctt tatttcacat tcaatatcca catgaatccc
    64321 acaaatacaa agaacagacc atacatgatt ggagatactt cttttcctct tttagctgct
    64381 aacatggtaa ttggatagaa gataaaacct aatgcaatcc catctgaaat actataagtc
    64441 aaaggcatgc cgatcaagat caagaatgaa gggatcgcaa tctctaagtt tccccattcg
    64501 atttgtcgca aagattgtgc catcaatact cctaccataa tcaatgctgg tgcagttact
    64561 tgtgaagtaa caactgatag taatggagaa aagaacaagc ctaacaagaa gaaaatccct
    64621 gtagtaatag ctgtgatacc tgaacgtcct ccaacggcga taccagctga tgattctaca
    64681 aatgcaccaa caggagaagt accaaataag gaacccgcaa gcatagctgt tgaatcagaa
    64741 gctaaagctt tccctacacg aggcatcttg ttgtctttca tgaaacctgc ttggtttgct
    64801 aatccaacta aagttcctgc tgtatcaaag aaagtcacaa gcaagaatgt cagcactacg
    64861 acccacattt gaagagaatt gatgtcccct acatgtttta atgcaactaa aaatgttggt
    64921 ttcaaacttg gtgctgcggc aacaatttca gaaggcattg gaatcaaacc tgtgaccaga
    64981 cctaaaatcg ttgtagctgc catcccgatg aagatgccac ctggtacacg ccgaacaagc
    65041 aagatagcag ttacgactaa tccaaaaatc gtcaaccaag tagaaccaac gttgagtgat
    65101 cctaatccta ctaatgtaga ttcattcgaa acgatgatcc caccttcgct cagaccaagg
    65161 aaagcgataa atagaccgat accgccagaa atcgcatatt tcaaatctgc tgggatcgca
    65221 tcaatgatca tttcccgcag cttgaagatt gtgatcaaaa taaaaatcaa agaagcaacg
    65281 aatacgccgg ctaatgctgt ttcccatgga atccccattc ctaaacaaac agaataagca
    65341 aaaaaagcat tgatcccaag agcaggtgcc gttccaattg gataacgggc taataccccc
    65401 attaaaacac agccgatcgc actggctaat gcagtcgcag taaacactgc tccttcatcc
    65461 attccagaag cacctaatac agttggattt acaaataaga tataagccat tgagataaat
    65521 gttgtaaatc ctgccagtac ctcacgtttt accgtggtgt tcaatttttc tatttcgaag
    65581 taggaaagta ttttttcctt catcttccat ccccctaaat ccgaacatta taaataaagt
    65641 ccgttaaaat ttcgatttat taataaaaca acgtgtttta tcatatacta aaacaaaaca
    65701 taagtaaaca aaaaattcgg attttaagca aaatccgaac gttccatctg attaaatccc
    65761 tttatctcaa agttcatgaa cattcacttt ggattacaag aatttcttta ttgtgttaat
    65821 aaagtttctt cattctagtc tcaaaaatca atagtgtgat ttgattttac catttcgttt
    65881 ctgttcttct ttgatgaatt cttttgtatc gacaggattc agattattta gtccgccaaa
    65941 acctgtatcg accatttttc cccagccttt tgtcttcttt tttcctgatt tgagattctt
    66001 tgctcgaagc ttctcactat gttttgctcg ccgatacttc aaataacctt ctaatcttcc
    66061 cattagatcc actgtttttc ctccttttta ttcaatcaga cgactcagct tttcctataa
    66121 caaaataatt gccttcaggg tcagaaaaat tgaaagtcaa gatgccattg ttatctgtga
    66181 tttctcctgg ttcttccatg ttctcgtaga tagtttcaaa ttcatccgta aaaaatacta
    66241 aagaaggcgg tggtcctaat acctctggtg aaaacttctg cacaaatact tttgggaata
    66301 cgcctaattc taattctttt gagatgctga gtacaatact cttaaattct tctggcaatt
    66361 cgattgtttc agaaatttct gcaccaattt tttctacaaa gaatcggcaa atcatctcta
    66421 cgtcattgac ataaagcatc acacgtgttt tttgtatcat catttgaccc ttctttctat
    66481 ttgattttct ttcctgtcta taaactgatt ccattatatc acgaaagcgc aaacaccttg
    66541 tgtttgatac tattcaagaa aaataaagca atagtttcta ggattgcttt cctccacaaa
    66601 ctttttttac aaaaaaaaaa cggcaatgaa tgccgctctt cttatttcga ttcttttata
    66661 attctgcttc tgattcatct ttggttagtg tgtgtctaac actagttacg ccaaatgttt
    66721 gatcgatttt ttccttcaac gcttcgattg cctgtgcgcc acgtgccgct tgttcagcat
    66781 tgatggattc aatgaccagc accgctgctt gtgtttcttc cgtcagcatc gttctttggg
    66841 cttcacgcca gttgagacag cgacagatcg ctccttgttc atcatagtag atgatttctt
    66901 ccggaagtgc cggagcatcg gaatctgcac ctaaaggcag gaatgattcg ccaccttggg
    66961 cttttcctaa atgcagattt cctgcgatct tttcgatatc ttctccgccg caaggtacgc
    67021 caaaagacaa ggaaatacta ttatagatat ctacaagcgg attgattggg aaaaattcac
    67081 gttcttgatt tgcacgtttc agtaaagctt caatagaaga acgtgcacct tttttagtct
    67141 tgaatgtggt aaatgcctga cgccactgag caatgacttc gttttggctg aatgtttctt
    67201 ctgtaaggta atttcttgct tcttttgctg cctcattcaa taattgatga tacgtttctt
    67261 cactttcttt tgttacgtgg ttatcgatac catttacgga taagatttcg atggttgctt
    67321 caggaaatac ttcccagaaa ttggtatcca ctattacttt tttcatctgt tcacacctct
    67381 tgattagaat aattgcttga tgaatagata gtctgtttgg ggatcatctc ccatataaaa
    67441 aacatgttcg ctgtatttga taaatccttt tttacgataa aaagcgagcg caacatcgtt
    67501 gtgttcccaa acaccgagcc aaatggctgt tttttgcttt tcttttgctt tttcaatagc
    67561 tgtatctagt aaaaatgtac cgataccttg atgtttaaat ttttttcgta catagattcg
    67621 ctcgatttct aaaaaatgat cagccatttc ctcagattga ctcgttcctg tatttagttt
    67681 caggtaaccc gcaggctctt gatcgatact cactaggaaa aaatcggttt ctttatcttt
    67741 tagctcttct gtaagttttt ctagtgcata agcttgtgtc aagtaatcag ctaaatgctc
    67801 cggtgaatta tcttttccaa atgtatctgt aaatgtttcg atactaattt gttgtagtaa
    67861 gtctacatct gaaggcgtca tttttcgaat ttcgtattta ttcacggctt cttcctttca
    67921 atagatcctt ttattgcctt ttttgacaaa attccaatct tcgctaacat tcttgcatac
    67981 tttatttaaa agatattcca attgttttgc ttcttcgtca gaaagaccat ttaatgcgac
    68041 tgcattggag tagttgtttt ctcgaatgat gaaaggatag atttctgctc cttttttagt
    68101 cggatagagt ttcttgattt ttttattttc tttatcttcc aaacgttcga tcatcccatt
    68161 ggattctaat ttcttgattg ctcgggcagt cgttgtacga tctactttga tcatttctgc
    68221 tagtttttct tggatgattc caggattttc gcaaatacgt actaaataaa gatactgtcc
    68281 tcttgttaaa tcgacttctt tgaattcgat attgctaata gaatctagcg ctcgggcaat
    68341 cattccgatg tctcgaagga tttcagccat ttcatcccac ctttattttg tttgtaagac
    68401 tagttcacct ctttttgttg caaatgcaac tattttcaat aaaaaaatca agttcttttt
    68461 taataactag taaagtatat tcttttcttc ttttacgaaa aagctcaatc acaatagatc
    68521 tggtttttgt tttctaaaat aagtaactgt ttcttcgttg ttcgcttttc tgatagcttt
    68581 ggcaactctt ctatactaaa aaatcccatg ttggaagttt cattattctc aataaacttg
    68641 gcctcttcac cgtggatcgc acaagcaaaa acaagtttat aatactgaaa aagctgtgga
    68701 atatcttttt gtttattcgt atcaaaaact gctcgcaact gagtagtttc tactgttaat
    68761 cctgtttctt catagacttc tttacgcaca ttttcttcag gagacaatcc tatttcagca
    68821 aatccaccag gaagtgacca ttctttcgtc cgtttatctt cgattagtag gaccttgcca
    68881 tcttttttga tataggcacg aacatctact tttggtgttg gatgtccttc tccaatcgtt
    68941 gtgagcgctt ttatttcttc gaaagtttct tttcctattt cactgatcag ttccaatgaa
    69001 atcgtccgga tctcctcaaa acgctcttta tcaaatacat cttttccata atatagacca
    69061 gcttgagaaa gtgcgagtag tcttttgtat tgagccaact tcttgttcat tctcttccct
    69121 tcttttttag caaatgtatg actatgtaat caagtataga agactggttt aattacggca
    69181 aataaatata atgaaatctg caataaataa aagaatgtta aaaaactcga gaacaaaaga
    69241 cattcgactt ctctggggct gtgaataaat ggcgttcaaa agcttgcatc tgcggtaata
    69301 agccccacca aacgaaaaat atgacgagct attcttgtct ggctgttctt attaattgag
    69361 gcaggacagc tttttcacaa cctccccact aaacggtgtt ctcctaccaa ctcctcggtc
    69421 acaagtcaca atattcatca aacatgagaa gctgtttttt tgaaattgct ccttgtgact
    69481 cggagctgaa cgacaggctc acgacctctc ggtaaacagc gttcaaaagc caatttttcg
    69541 atattaagcc atttctttgt tacttattgt cattgatttc tttttctaat ttatccaata
    69601 gtggagtgta atccacttga gtatagtctg ttacatcaaa ttcatatagt gttcctaact
    69661 ggaatttgtc atattttcgg tcggcgatga tctttttgaa tgcttctttc gtaatatgat
    69721 tggtcccttt cgttcgatct tccaatacgt caccatagtg ataatgatcc atgatatagc
    69781 tcaaatgacg atctgattca cgatcacgtt tgtaccgacg ttgccataac acttcaaagt
    69841 ctgctgttag gcgaatcgtg atcacctgat atccgtatct atctgctaat tcttggagtc
    69901 gtgctttttg cttatcacta aaaggatact cggacacaat cactttcttt cctgcttcca
    69961 tatacaaatc aagtgctttg taatagaaag gataaacttt cgtcctttct tgttccgccc
    70021 gttcttccaa attgttaaac ccgatggatt ctgcatagta ttccttgatt tcatcgagcg
    70081 tgatggcata catatctgga aatcgttccc gtagtttatt cataagatat gtttttcctg
    70141 taccaggact accagccaga agaatgaaat actttttcat ctcatttatt tcctaagtta
    70201 attggacttt ccaagttcat aaacagtcca atcttatgct tgacaatttc ttttactgct
    70261 tcatttgctg gaatcacatt atggcgaaga gacttgttga tttctgtttc actaaaggtt
    70321 tctttagcta ctttcgtcca gttgactaaa agctccgttc caacattgaa tttgcggatc
    70381 ccgttattga tcaattcagg ataatcttct tctttcacac ctgttcctcc atggataact
    70441 agggggacat caactactgc atcgatttct ttcagcaagg gaatgtttac ttctgttttt
    70501 gatttgaatt gtccatgatt cgtaccgata gcaatagcta atgcatccac gcctgtagct
    70561 tctacaaatt tcactgcgtc ttccggtctt gtatatacct tgtcattttc agcgacatgg
    70621 attccttctt ctgtaccgcc gattgttcca agttctcctt ctacggaaac accgtgcgca
    70681 tgggcatatt ctactactgc ttttgtcttc aggatatttt ctttgaaagg cagatgggac
    70741 ccatcataca tgacagaagt atatccgctg tcgattgctt ctttgatatc atcaaagtct
    70801 cgggcgtggt ctaagtgcaa gactgcatca accatttctt cttctgcaat agctgtcatt
    70861 acattgacta acacatgcat gccgatatat ttagcggtat cgacacttgt ttgaataatg
    70921 atcggcgaac ccatttcttt tgctgcgcct agcatagcag gaagcatttc taggttatgc
    70981 gtattaaaag ctccaactgt aaaattcaac tcttctgctg tttttgttac ttctttcaat
    71041 gttgtataca tcttttattg ccaccttatc tttttatttg tttcctttga tcgttacttg
    71101 ttttgcaatt tgtcgcatct catccatttt gcccatgtag taatcgatcc cttgatcatc
    71161 accagcacga gcagcatctg cacgcttctg gttatagagg ctcatcagtt ttttataccc
    71221 atctccgatc gtctgtttat tttccaaact cttttctaaa tattggatgg cttgatcgtt
    71281 cacatacaat tcagaaaatt taagtccaac ttgttcataa agtttcgcta atttatgctt
    71341 atcttgggta gtggaaatct cttgtttcaa ttgtgtaatc tctgattgaa tcttttcggt
    71401 cgcttctggc gatagggctt tttcttcttt tgccagaact tttttcggtt ctttttcttt
    71461 tttcttaaaa aatccaaaca tcattttccc tactttcaat taaaatgctt tcaaaactgg
    71521 gcttaagatc caggcatata agagtgctgc ggctactgta tctacatcgg ttgctgtagc
    71581 attgttgaat cccatcgaat taaagatcgt tactagcaaa gcgggcaata atgtaataaa
    71641 gaaaccatga gcaataccgc caatgatcgc tcctcggcgt ccgccaactg cgttgccaaa
    71701 tatccctgct gtccctccgg caaagaaatt ggttagcata ccaggtaaaa tcatcgctaa
    71761 gccgaacatg ggcaaagtaa acatggcaat aatcgtacca atcgttgtcg taatgaaacc
    71821 taaaatgaca gcatttgggc tataaggaaa gaaaactgga caatctaagg cagggatcgc
    71881 atcaggaact aatttcatag ctatccctcg aaatgccggc acgatttcac ctaacagtag
    71941 acgtacacca gctagcaata catacacacc cactacgaat tggatggctt gtaaaaaggc
    72001 aaacatgata tagttttgat ctcctgataa ttcagaagcg aatggttcgc ctgcaaataa
    72061 aacagtgatg atatatagcg ggaccatcac gaccatgaca gacaaataag tatcttgcag
    72121 aaattcgaaa tgtgtcggca acttgatatc ttcgatcgac tttttatttt cgcctttctc
    72181 accaaaaagc ttagcaacac cggcttcaaa taagtacccg atcgtacaaa aatgacctaa
    72241 agcaatatca tttgatccag tgattttacg aatgatcggt tgcgctactg ccggcatagc
    72301 aatggcgaaa caagctccga taaaaccacc gaccaagatc aatacgatcc ctcgcagacc
    72361 ggcaaaatag ccaaagactg tcgtcatcgt tgccatccat aaaattgctt gaccagttaa
    72421 aaaaatgtac ttccattttg tgaaacgagc caaaataata ttgaatacaa aaatggctaa
    72481 gaacgtcagt gcaatatctc tacctaaacc caaatcattc attgcttgac cattgataga
    72541 ttcaatagaa gggatgatcc cttgcatatg aaatccttca gtaaagattt tcccgaaata
    72601 agttaaactt ccaacgatga tgctcgaacc ggcactcaac acttgaaatc ctaggagtgt
    72661 ctttaacgtg ccagagatga cttgtcctgc tgatttcttc tgcagtagta gacccaacat
    72721 agcaatcaat gcaatggtga tcgatgcctg agtcaaaata ttttcgatga taaaattgat
    72781 aacgcccat
//
LOCUS       DBBGSZ010000011        68938 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.011, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000011 DBBGSZ010000000
VERSION     DBBGSZ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 68938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68938
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.011"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            210..1211
                     /locus_tag="ACIZE5_001018"
     CDS             210..1211
                     /locus_tag="ACIZE5_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HGC6108177.1"
                     /translation="MTSTVFIILLGFVCRKKGIFSESVGKILSKVVLTVALPALAFRA
                     FMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYKGDKQTTLRVLTIFGSTTFF
                     GTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGLKMEAKNIKAMFVNPIIIAT
                     FAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPWLFQPMDYLAGLSSPLAWLA
                     IGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILAVLTATNILPVNFEALATIV
                     IMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVLTPVWIVVLQMIHGIGLFS"
     gene            1230..2249
                     /locus_tag="ACIZE5_001019"
     CDS             1230..2249
                     /locus_tag="ACIZE5_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HGC6108178.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(2351..3067)
                     /locus_tag="ACIZE5_001020"
     CDS             complement(2351..3067)
                     /locus_tag="ACIZE5_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGC6108179.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(3036..3821)
                     /locus_tag="ACIZE5_001021"
     CDS             complement(3036..3821)
                     /locus_tag="ACIZE5_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC6108180.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(3812..4561)
                     /locus_tag="ACIZE5_001022"
     CDS             complement(3812..4561)
                     /locus_tag="ACIZE5_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HGC6108181.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            4859..5383
                     /locus_tag="ACIZE5_001023"
     CDS             4859..5383
                     /locus_tag="ACIZE5_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HGC6108182.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            5399..6898
                     /locus_tag="ACIZE5_001024"
     CDS             5399..6898
                     /locus_tag="ACIZE5_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HGC6108183.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(6986..7588)
                     /locus_tag="ACIZE5_001025"
     CDS             complement(6986..7588)
                     /locus_tag="ACIZE5_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HGC6108184.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            7692..8648
                     /locus_tag="ACIZE5_001026"
     CDS             7692..8648
                     /locus_tag="ACIZE5_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGC6108185.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(8953..9909)
                     /locus_tag="ACIZE5_001027"
     CDS             complement(8953..9909)
                     /locus_tag="ACIZE5_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC6108186.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            10083..10643
                     /locus_tag="ACIZE5_001028"
     CDS             10083..10643
                     /locus_tag="ACIZE5_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108187.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            10636..11460
                     /locus_tag="ACIZE5_001029"
     CDS             10636..11460
                     /locus_tag="ACIZE5_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HGC6108188.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            11470..12087
                     /locus_tag="ACIZE5_001030"
     CDS             11470..12087
                     /locus_tag="ACIZE5_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HGC6108189.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            12105..12788
                     /locus_tag="ACIZE5_001031"
     CDS             12105..12788
                     /locus_tag="ACIZE5_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HGC6108190.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            13471..14754
                     /locus_tag="ACIZE5_001032"
     CDS             13471..14754
                     /locus_tag="ACIZE5_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6108191.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            14770..15657
                     /locus_tag="ACIZE5_001033"
     CDS             14770..15657
                     /locus_tag="ACIZE5_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6108192.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            15674..16510
                     /locus_tag="ACIZE5_001034"
     CDS             15674..16510
                     /locus_tag="ACIZE5_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6108193.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            16513..17136
                     /locus_tag="ACIZE5_001035"
     CDS             16513..17136
                     /locus_tag="ACIZE5_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108194.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            17133..18425
                     /locus_tag="ACIZE5_001036"
     CDS             17133..18425
                     /locus_tag="ACIZE5_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC6108195.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      18784..18881
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            18997..19578
                     /locus_tag="ACIZE5_001037"
     CDS             18997..19578
                     /locus_tag="ACIZE5_001037"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HGC6108196.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            19581..20888
                     /locus_tag="ACIZE5_001038"
     CDS             19581..20888
                     /locus_tag="ACIZE5_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HGC6108197.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            21304..21792
                     /gene="purE"
                     /locus_tag="ACIZE5_001039"
     CDS             21304..21792
                     /gene="purE"
                     /locus_tag="ACIZE5_001039"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HGC6108198.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            21785..22909
                     /gene="purK"
                     /locus_tag="ACIZE5_001040"
     CDS             21785..22909
                     /gene="purK"
                     /locus_tag="ACIZE5_001040"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HGC6108199.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            22922..24217
                     /gene="purB"
                     /locus_tag="ACIZE5_001041"
     CDS             22922..24217
                     /gene="purB"
                     /locus_tag="ACIZE5_001041"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HGC6108200.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(24339..25727)
                     /gene="ltrA"
                     /locus_tag="ACIZE5_001042"
     CDS             complement(24339..25727)
                     /gene="ltrA"
                     /locus_tag="ACIZE5_001042"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HGC6108201.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
     gene            complement(26296..26673)
                     /locus_tag="ACIZE5_001043"
     CDS             complement(26296..26673)
                     /locus_tag="ACIZE5_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108202.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            26929..27657
                     /gene="purC"
                     /locus_tag="ACIZE5_001044"
     CDS             26929..27657
                     /gene="purC"
                     /locus_tag="ACIZE5_001044"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGC6108203.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            27657..27911
                     /gene="purS"
                     /locus_tag="ACIZE5_001045"
     CDS             27657..27911
                     /gene="purS"
                     /locus_tag="ACIZE5_001045"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HGC6108204.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            27913..28584
                     /gene="purQ"
                     /locus_tag="ACIZE5_001046"
     CDS             27913..28584
                     /gene="purQ"
                     /locus_tag="ACIZE5_001046"
                     /EC_number="3.5.1.2"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HGC6108205.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            28585..30807
                     /gene="purL"
                     /locus_tag="ACIZE5_001047"
     CDS             28585..30807
                     /gene="purL"
                     /locus_tag="ACIZE5_001047"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HGC6108206.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            30792..32231
                     /gene="purF"
                     /locus_tag="ACIZE5_001048"
     CDS             30792..32231
                     /gene="purF"
                     /locus_tag="ACIZE5_001048"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HGC6108207.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            32254..33306
                     /gene="purM"
                     /locus_tag="ACIZE5_001049"
     CDS             32254..33306
                     /gene="purM"
                     /locus_tag="ACIZE5_001049"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HGC6108208.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            33303..33881
                     /gene="purN"
                     /locus_tag="ACIZE5_001050"
     CDS             33303..33881
                     /gene="purN"
                     /locus_tag="ACIZE5_001050"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HGC6108209.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            33878..35413
                     /gene="purH"
                     /locus_tag="ACIZE5_001051"
     CDS             33878..35413
                     /gene="purH"
                     /locus_tag="ACIZE5_001051"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HGC6108210.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            35429..36703
                     /gene="purD"
                     /locus_tag="ACIZE5_001052"
     CDS             35429..36703
                     /gene="purD"
                     /locus_tag="ACIZE5_001052"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HGC6108211.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            36825..37739
                     /locus_tag="ACIZE5_001053"
     CDS             36825..37739
                     /locus_tag="ACIZE5_001053"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HGC6108212.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(37872..39437)
                     /locus_tag="ACIZE5_001054"
     CDS             complement(37872..39437)
                     /locus_tag="ACIZE5_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6108213.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(39430..40881)
                     /locus_tag="ACIZE5_001055"
     CDS             complement(39430..40881)
                     /locus_tag="ACIZE5_001055"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGC6108214.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(40895..41911)
                     /locus_tag="ACIZE5_001056"
     CDS             complement(40895..41911)
                     /locus_tag="ACIZE5_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6108215.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            42131..43219
                     /gene="chvE"
                     /locus_tag="ACIZE5_001057"
     CDS             42131..43219
                     /gene="chvE"
                     /locus_tag="ACIZE5_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     substrate-binding protein"
                     /protein_id="HGC6108216.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            43273..44799
                     /gene="mmsA"
                     /locus_tag="ACIZE5_001058"
     CDS             43273..44799
                     /gene="mmsA"
                     /locus_tag="ACIZE5_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     ATP-binding protein"
                     /protein_id="HGC6108217.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            44801..46006
                     /gene="mmsB"
                     /locus_tag="ACIZE5_001059"
     CDS             44801..46006
                     /gene="mmsB"
                     /locus_tag="ACIZE5_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     permease"
                     /protein_id="HGC6108218.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            46263..47240
                     /gene="guaC"
                     /locus_tag="ACIZE5_001060"
     CDS             46263..47240
                     /gene="guaC"
                     /locus_tag="ACIZE5_001060"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HGC6108219.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            47504..48928
                     /locus_tag="ACIZE5_001061"
     CDS             47504..48928
                     /locus_tag="ACIZE5_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGC6108220.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            complement(48970..49227)
                     /locus_tag="ACIZE5_001062"
     CDS             complement(48970..49227)
                     /locus_tag="ACIZE5_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108221.1"
                     /translation="MPIRILTALVNKITIRKAFYISSAFFLFSNQTYNHLFLFKNVGV
                     IQFCCKHLFYLHIVNGRTNNGFFLVSLYRILFPKKKKQLEI"
     gene            49389..50498
                     /gene="pdhA"
                     /locus_tag="ACIZE5_001063"
     CDS             49389..50498
                     /gene="pdhA"
                     /locus_tag="ACIZE5_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HGC6108222.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            50501..51478
                     /locus_tag="ACIZE5_001064"
     CDS             50501..51478
                     /locus_tag="ACIZE5_001064"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HGC6108223.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            51503..53146
                     /locus_tag="ACIZE5_001065"
     CDS             51503..53146
                     /locus_tag="ACIZE5_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HGC6108224.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            53154..54560
                     /gene="lpdA"
                     /locus_tag="ACIZE5_001066"
     CDS             53154..54560
                     /gene="lpdA"
                     /locus_tag="ACIZE5_001066"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HGC6108225.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            54722..54997
                     /locus_tag="ACIZE5_001067"
     CDS             54722..54997
                     /locus_tag="ACIZE5_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HGC6108226.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            55003..55770
                     /locus_tag="ACIZE5_001068"
     CDS             55003..55770
                     /locus_tag="ACIZE5_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HGC6108227.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            55938..57767
                     /gene="typA"
                     /locus_tag="ACIZE5_001069"
     CDS             55938..57767
                     /gene="typA"
                     /locus_tag="ACIZE5_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HGC6108228.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            58028..59800
                     /gene="recQ"
                     /locus_tag="ACIZE5_001070"
     CDS             58028..59800
                     /gene="recQ"
                     /locus_tag="ACIZE5_001070"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HGC6108229.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            59914..60216
                     /locus_tag="ACIZE5_001071"
     CDS             59914..60216
                     /locus_tag="ACIZE5_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HGC6108230.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            60219..61382
                     /locus_tag="ACIZE5_001072"
     CDS             60219..61382
                     /locus_tag="ACIZE5_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGC6108231.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            61408..64836
                     /locus_tag="ACIZE5_001073"
     CDS             61408..64836
                     /locus_tag="ACIZE5_001073"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HGC6108232.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            64857..65981
                     /locus_tag="ACIZE5_001074"
     CDS             64857..65981
                     /locus_tag="ACIZE5_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP-associated domain-containing protein"
                     /protein_id="HGC6108233.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            65962..66408
                     /locus_tag="ACIZE5_001075"
     CDS             65962..66408
                     /locus_tag="ACIZE5_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HGC6108234.1"
                     /translation="MIAVIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESA
                     KVCQLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQ
                     LQSLLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            66392..66730
                     /locus_tag="ACIZE5_001076"
     CDS             66392..66730
                     /locus_tag="ACIZE5_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HGC6108235.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            66849..67409
                     /gene="rsmD"
                     /locus_tag="ACIZE5_001077"
     CDS             66849..67409
                     /gene="rsmD"
                     /locus_tag="ACIZE5_001077"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HGC6108236.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            67406..67897
                     /gene="coaD"
                     /locus_tag="ACIZE5_001078"
     CDS             67406..67897
                     /gene="coaD"
                     /locus_tag="ACIZE5_001078"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HGC6108237.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            67887..68930
                     /locus_tag="ACIZE5_001079"
     CDS             67887..68930
                     /locus_tag="ACIZE5_001079"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HGC6108238.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
BASE COUNT        22169 a        12015 c        15130 g        19624 t
ORIGIN      
        1 aaaaatcact ttacataagt ttcaaaagtt tctttaattt cctattgttc aataagtaac
       61 aatgtaaaga taaaattaaa aatgttaata cgtattagca aaataaaagc tttttttatt
      121 gtgaataaat gaacataatt aggaggagaa agatgaactt atttgacatt tttcgatcga
      181 ctttgacaga tatgtcgatt gtcagtgcaa tcacttcaac agtttttatt atattattag
      241 ggtttgtttg tagaaaaaag gggatttttt ctgaatctgt tggaaaaatt ctatcgaaag
      301 tcgtcttaac agtggctttg ccagcactgg catttcgagc tttcatgcaa gatatcaata
      361 cagaattact gatgcaagga atcaatgtct tgatttgggg attagttatt tatattattc
      421 ttattctagt ttcaaaacct tttttcttaa gctataaagg ggataagcaa acaacgttgc
      481 gtgtcctgac gatctttggt tctacgacct ttttcggaac gcctatcgtc agtgcgattt
      541 atggtcctgt cggcgtgatg tattcctcaa ttttcaatat tggctaccga atctttttgt
      601 attcttatgg atacataaaa atgagtggct tgaagatgga agctaaaaat atcaaagcga
      661 tgttcgtcaa tccaatcatt atcgctactt ttgccggcct tttcatttgg ctgttccaag
      721 ggtatctgcc acaagtgtca gttacaggtg cagaaggaga gataagccaa gtagcgtttt
      781 tgcgaattga ccagactgca ccgtggctat ttcagccgat ggattattta gctggtttaa
      841 gttcaccatt ggcgtggcta gcaatcggcg caacattagg tgaagtaagc ttcaaaaaag
      901 ctgcatctga aaaaacttca tggtattaca gtctagtcaa agtggtattt gtacctgcat
      961 tgaatatcgt gattctagca gttttgacgg caacgaatat tctaccagtc aattttgaag
     1021 cactggcaac aatcgttatc atgatggcta caccagctgc aacagtggca gcagcctatg
     1081 ctatcagttt tgatagggag gcacttttag cctccaatgc atccttactg tcaactattt
     1141 ttgctgtggt actgacacct gtatggatcg ttgtattaca aatgattcat ggcataggtt
     1201 tattttcata agaaatggag gaagaaagta tgagaatcgc atgttacggt gttcgtccga
     1261 acgagataga tttttttgaa aaattgaata tttaccatta tgatctcagt ctttatgaag
     1321 aactgttgac acatgacaat atcgtgtcag caaaggacca tgatgctgta ttgttgaggg
     1381 gaaattgtat agcagatgag accaatcttg caaaaatgca ggaatatggg attcgttatg
     1441 tttttacacg gactgtggga gtcaatcata tcgatctaca agcggcagct gattttggta
     1501 tgacagtagc ccgtgtacca tcgtattcgc caaatgcgat agcagagtta tctttgactt
     1561 ttgccatgat gcttttgaga aatactgcgt atacgacgat ccgaacatct ttcaaagatt
     1621 ttcgagtgga tgagcaaatg tttagtcgtg aaatcagaaa ttgcacagta gggatcatag
     1681 gaacaggcag gatagggttg acggaagctg ttttgtttaa gggactagga gccaaagtga
     1741 tcggctacga tattcatcag acagaagctg ctaaaaaagt attgacgttc cactcgcttg
     1801 aagagttatt agccaaaagc gatattgtca gtattcatgt acctcatatc ccaggtgaaa
     1861 acgatcaaat gatcaatgaa ggatttttag ctcaaatgaa aaaaggtagc atcttgatta
     1921 atacagcccg tggagagctt caagataatg aagctatttt aagagctttg aaaagcaatc
     1981 atttagctgg ttttgcaacc gatgtttttg caaatgaaac agaggttttt ttccgatcct
     2041 tcaagccatg ggagacgatt ccagaccctg ctatccagca attagtagaa atgtacccta
     2101 gagttcttgt aaccccgcat gtaggttcaa atacagatga ggcattatca aatatgattt
     2161 cgacaagttt cgagaacttt cgtgaaataa tagaaactgg aaaaacgaaa aatgaggtat
     2221 ctcttcctaa agcccgtcaa ttaagataag aaaacatgga tattcgtcaa taaaatgttt
     2281 aaaaatagtc caagtaaaca gttgttactt ctgtatactt ggactatttt gtatgggata
     2341 attcgatgac tcaacagtaa tctgtgagct ttttccgccc attctttgtc aattcataac
     2401 aggttagcgg ccggccgatt tccaaatatt tgattctttc gttcaatata tcttgttcta
     2461 ctaaaaaatt caaatatttc ttgacggata tacgtgacag tgagcttttt tgagccagtt
     2521 cttttgttga aaaaatagta tcttctttta gaataaatgc acttattttt tttaaagtca
     2581 gttttgacag acctttaggc aaatcgatga atgatggtat ttcgtgaatg ggagtggtgt
     2641 ggttgaatac ttgatcgatc aatttctgat cggctttttc agtcgtttgg attgtctgag
     2701 agaaagcaag atacttttcg atcgccagct gaaaacgttg caaagtgaac ggtttgatca
     2761 aataatctaa ggcaccgtag cggatcacat tctttatggt ttcgatatca tctgcagcag
     2821 tgatcaaaat cactgggata tcatttcctt gctgtctaag ccaagataaa aaatggatac
     2881 cactttcgcc aggcatgtat acatcaagca gcagcagatc tgcgtttttt tgtctgaaat
     2941 atttttttcc ttcttctaca tttctgaaac tttcgattac gttcatatta gggatgcttt
     3001 ccacaaaagt acgattcaat tctgcaacca ttggatcatc ttcgattatc aggacatttg
     3061 tcatcatttt gatcttcctt ttttggtaat tctagataga cgattgtacc gccatttgtt
     3121 tgtttggaaa attctaaaaa tccaccgtgg cgtttgacga ttgaatggat gagattcaat
     3181 ccaaacccac gattgattcc cttcgtcgaa aaacctagcg taaatatttt ttctgagatt
     3241 tcttctgata tcccgacacc gtcatcgcag acggtcacga tgaatacttc agcttctgtg
     3301 tcatagttta aatgaatccg gacctgtccg tttctttcat gtttttgtag cacggcttct
     3361 tttgcattat caagtaagtt ccctaacact tgcaaaagtg aatggatgga gtcatccatc
     3421 tccattttag ggataaaaga atcgctttct aacagcattt caacagattg ttctttggct
     3481 tcgtttattt tgcctaataa aaaaccggca attgcaggta ctttgatcag acttgagact
     3541 tggccaatct cttttttata attttgattt agctgctgga taaaatgggt gacttcttca
     3601 tacttcttca aatcaatcaa accagaaatg acatgaagtt tattcatgaa ttcatgggtt
     3661 tgagctctca tggagtttat atattgtttc gtccccccaa gctcctccat taatttcatt
     3721 acttctgatc gatttcgtaa agttgcgact gctcctaaaa aacggtcatt gctaaaaaga
     3781 ggtgtaacgc tagaaatagt ttctatccca tttaaataca tggattgagt ccgaacggtc
     3841 gtttgatgct caatcgtctc tttaaacaaa acgtcatata gattatcact gatttttttc
     3901 ctacttcgaa atccaatagc tgctctgttt ggtagaaaat gttttttgca ggtgtattga
     3961 tcaagaggat agttttatca gaagagatgg ctaagattcc ttcatctact tcattttcga
     4021 taatcgtttt ttcacttaac tgttctgcta tttcttgtgg ttcaagtcca agcagtactt
     4081 ttttcatttt ttgggcaaga aaaacggcgc ctatgatgcc tacgctaagt ccaataatca
     4141 atgaaaaaac aatcattttt tgtccatctt tgacttgatt gtcaatcgtg ttgtttgtta
     4201 agccaacaca aactgcacca ataatctctt gatcataata aatagggacg aaatagcgga
     4261 agccgaaccc taacattcct tctttttcag agaaaaattc ttgtcctcca atcacttttt
     4321 tcacatcttc atgacttgag aaaggaagac cgatgtaact tgggtctgcg tgagaatatc
     4381 gaatgccttc agggtccatg acaacgataa aatctaaatt cgatgcaatc atgatttcat
     4441 ttgttattcc ttgaatcgca tgtgtcgggt caccagtctg cagctttttt tggatgagtt
     4501 tatcattggc aacgatttta gcaatgctag agattttatc tgacacacta gatcggttca
     4561 tcgaaagaat aaaattcctg atcaatatgg cagaaacaat caaagaaacg aatgtggaga
     4621 aacaaacgac aaggatgatc gtgttctgga gctttaatgg ttttttctta aaaaaaggaa
     4681 acataggcta cctcgaaaga atttattgtg aaaattttaa catgaaaaca aaaatttaac
     4741 aaattgtcaa cgataaacac aaccttccta taaaaaacac cactgagtcg gtaaaagaag
     4801 ctatacagaa ttttcaaaca ttggtatgat agacgtagaa atggaaggag gcgtgtatat
     4861 gataggggga atcgcacttg agacgattta ttggtataca ttgctgattt gtgcaggatt
     4921 ggcagtccta ttgattattt ttggagatgt attcgatttt gatggcccgc ttgatccgat
     4981 gcttattatc ccttggttaa ctttcacaag cttatttggt tttctaggtg agcgtttaac
     5041 agatcaatca tctttatttt tatttattgc tagtggaggc atatcgatag tgttggtatt
     5101 tttgcttaat ttctatatat tgatgccgat gaaacatgcc gaatcaacga tgtcgtcttc
     5161 tgaaaaaact ctggaaggac aagtagctgt tgtgatcaca ccgatccctg tacgaggtat
     5221 gggagaaatt cagttgaaaa gtgttaccgg ttccattagt cgtccagctt gtttttacag
     5281 cccccaagaa cagacagctg agcggggaac gaaagtattg atcattgaga tcaaggaaag
     5341 aatctgttat gtcatgcctt atgaaagcat gataaaagct taaaggagcg tgtgttaaat
     5401 ggaaatacca gttgttttta tcgcgatcgc aatcgcagct ttgattttac tgatgttgct
     5461 gatcgtcttt gtagcgaagt accagacagc aaaaccggat gaagcgttga tcatcagtgg
     5521 aagttattta ggaagcaaaa atgtgcacat tgatgaaagc aataacaaaa tcaaaattgt
     5581 gcgtggaggt ggcgcattcg tcttgccagt ttttcaacgt tcgaatcgga tcagtctatt
     5641 atcgagtaaa ttggacgtct ccacccctga agtgtatacg gaacaaggcg taccggtgat
     5701 gtgtgatggt acttcgatca tcaaaatcgg ttcatctgta gaagagattg ctacagcagc
     5761 agaacagttt ttaggcaaga caagagaaga actggaaaat gaagcaagag aagtattaga
     5821 aggacacttg cgctcgattc ttggttctat gactgtagaa gaaatctatc aaaatcgcga
     5881 taagttcagt caaagcgtac aagaagtcgc ttctgtagac cttgcaaaaa tggggttgat
     5941 catcgtttct ttcactatca aagaggtcag agacaaaaac ggttatcttg actctttagg
     6001 gaaaccaaga atcgcccaag tcaaaagaga tgcagatata gcagaagcgg aagctctaaa
     6061 agaaacgcgt atcaaaaaag ctcaagcaga aaaagaatca caagcagctg aattacagcg
     6121 acaaacagag atcgcagaat cattaaaaga aaaagaactg aaattagcaa cctacaaaca
     6181 agaacaagat gttgctaaag caaaagcaga ccaagcctac aatttagaaa gtgcccgagc
     6241 acaacaacaa gtaatcgaac aggaaatgca gattaaaatc gtagaacgtc aaaaacaaat
     6301 cgaactggaa gaaaaagaaa tcacacgtcg tgaaaagcaa tatgattcgg aagtgaagaa
     6361 aaaagcagat gccgatcggt acgctaaaga acaagaagca caagctcaaa aagtcaaaga
     6421 agtgactgaa gccgaagcag aacgattccg tgtggaagca ctggcagaag cggaagccaa
     6481 taagacacgt ttagctggac aagcagaagc cgaagcagca ctagcaaaag gaaaagcaga
     6541 agccgaagca aaacaaaaga tcgccaatgc cttcaaggaa tatggcgaag cagctgtctt
     6601 gagtatggtt atcgatatgc taccgcaatt gatgcgcgaa gcagcacagc cgctaggaaa
     6661 tatcgaaaaa atctctgttg tcgatacagg aagcagttca ggagaaacca gtggagcgaa
     6721 ccgagtgaca aattatgcca caaatttgct ttcttctact caagaaacac taaaagcgac
     6781 aacaggactt gacttgaagg aaatcgtaga gaatttgtcg acacgtggga ctactagcca
     6841 agtaaatatg tatgaagcgc caaaagaggc agaacaaaac tcgatgaagg aagaataaag
     6901 tagtacactt caccgttcaa tcaaaaatgg aggaagactt tttaaagttc ttctctccat
     6961 ttttttattt tattgcaaaa gaaaattagt cctcgctatt tttcttttgt ttttggatct
     7021 tagcttctat ctcttgtaaa tttgttctta gcaatcgttc tttcttttgg agttcgacca
     7081 aatcttctga tagttcttcc ttcttttctg tttcaggagg acgaagaaag aaattgatac
     7141 cgattgcaat gaatgtccct ataaaagtat ctagtacacg ttggatagca tacaaagcgg
     7201 attcgccttg agggatgctc aacgcaatca gcaacaacgt agctattgcg gaaatgatac
     7261 cggaattatt gttaatacca tctgacacga cgatcacaat aataactaga ataggaagca
     7321 agatcaattc taccaaaaaa tcattgtgaa aatagctttt gacaaaaaaa taaatgatag
     7381 ctaatgtacc acctaatgta ttgccgatga tcctagactt tccaaaagaa acggttgtag
     7441 tcaagtcctg acgcaaagaa aaaacagcag ataatgcagc aatcatcggg attcctcgtt
     7501 gagtcaaatg aaaaaacaag atacataaaa aaacagctaa ggcacttttg atcgtacgca
     7561 tacctagtcg aaaacggcca aattgcatag agattctcct ttttggtctt tttactatca
     7621 tacctaaact tttgtctgat agctagtttt tcattattca agtataatta aaataaaaaa
     7681 gggggaagta aatgcgtata ggaatgcgaa cagtcaaaac agtgatcagt gtcttctttt
     7741 cgatggtcac agcgggtagc ttatcgctgt tgtattggcc agctgcaggg atcattgcat
     7801 tattaagtgt aggaaatacc aagcgctcta cattgcgtac gggcatgaat cgaatcgcag
     7861 cctttatatt agctacggca acagcactgt tcagtttttt tgctgttggg tatactattt
     7921 ttggcttcag tcttttttta ttcctgttca tcccgcttgc ctctcgcttc aaattaaccg
     7981 aagggatagt agtaaattcg gttttggtca ctcattattt agtggaggaa aacatgtctt
     8041 ggcagctgat cggcaatgaa gcgggattaa tggcgattgg attagtattt gctttgcttg
     8101 caaatgttta catgccagat cgtacgaagc agctgaagga aaaccaaata cagatcgaaa
     8161 aagaatttcg aaatattttg agacaaatgg cagaatttct tttatcagaa aataaagaag
     8221 atgtgcagat caaatgcgaa catttactga cattcattcg cgaaagccaa gaagatgcca
     8281 gagaacatca agaaaactac tggctcagac agccgctata ctacgaaact tacttctcta
     8341 tgagaagagc acaggccaat gtgattaaag acatgctgga aaatctagag agaatccagc
     8401 aaccagctta ttatggaaaa catatctatg gtttattgat ttatactgca gaaacatttt
     8461 cagagtcaaa tgatggcaga caaattttaa cacgtattga agaagtttat gtattgtatc
     8521 ggcaaatgcc tctgccgact agtcgccctg aattcgagga tcgagcagaa ttgttccagt
     8581 ttttgcagtc ttttaaaagt tttattgaaa tcaaggcaga attctcccaa caaaaaatcc
     8641 aaaaatagag gttgtgaatt cagctaatat tcaggtcaaa aagctgattt cacaacctct
     8701 tctttaaacg gtgttctcct gtcaactcct cggtcacaag tcacaatatt caacaaacat
     8761 gagaagctgt tttttgaaat tgctccttgt gactcggagc tgaacggtag gctcacaacc
     8821 tctttcttaa acggtgttca aaagctttcc tctgcggtaa taagtccagc caaacgaaaa
     8881 ataggaggag ctatttttgt ttggctgttc ttattacttg atgcagaaca gctttttcac
     8941 aaccttttaa aattacatat ttttccatag aacttgcatt tgatccaaga tttcgatgac
     9001 atcttttgtc aagaagagag agcgattggg caagtcacct tcaatcatgt gtaccatatt
     9061 ctttatttcg taattcattg cttcagatgt attcccgctt tcgatgaatt cctttgtacc
     9121 atctgtaaat aagatctccg cacgatcagc acgcgggtaa tcagcaatcg tcacataacc
     9181 gttctcaaag gcaacgatac cgacttttgg catttttgcc tgaaaagtca agctgacagc
     9241 agcaagttca ttttctttgt tacgcaagat agtgacggat tgttcgtcca cgcctgtttc
     9301 aaaaggaacc attgtagagg caactacttc aggttgagag ctcaaaaaga aacgagcgaa
     9361 agatacagca tacgtaccga tatccaacag agctcctcca gctaattctg gattgaagaa
     9421 ccggttttta gggtctggtt ctttgtaact gccgaaaggt gcttggatca tttttaaagc
     9481 ccccagtttt cctgtatcca ttattgagcg taactgctga taaagtggca tgttgaagat
     9541 tgtcatcgct tctgctaaga tcaaattctt ttcttctgct aagcgcatag cgtcagccag
     9601 ttctttttta ttcatcgtga tggctttttc acatagaacg tgtttgcctg cttccaatgc
     9661 tgccaagata tggtcgatat gctgtctatt tggtacagca atgtacacga tgtcgatttc
     9721 agcatcgtct aacatttctt gatagcttcc gtaagctttt ggaatattgt aacggtgagc
     9781 gaagttttcc gctttttctg aagttctgga agcaactgct gttagttcgc tcgtctcttg
     9841 attgaagctt tcggcaaact catgtgcgat ggtaccaaga ccaacgattc cccattgata
     9901 ttttttcatc tgaaaacgct ccttcatagt tggattgagt ttcttgtctg tctattatta
     9961 taacaaaaat cacgaagaat aaagaggaga ggacttgaaa cattaaaaaa aatgaaagca
    10021 gcgatttaag aggtgctttt tgatcaaaac ttaagtagaa tagttaaaag gaggggataa
    10081 acgtgcatca agtatatatt gatcttatta tgagtgtatt attagaacag tttgaaactg
    10141 aaaaaaattt tttagatgaa tacttgctga tcagtccaga acaatggcaa aaatggaaag
    10201 atggcgagaa aaatctgcca tctgaagcga tgcagaaagt aaaaaatctt ttcactgatt
    10261 atgaatggat gctaacgcaa aagattttgc gtcaaacgat tatttttccc gaaaaacgaa
    10321 acgttgccgt tgcagagtac aagcaaatca aaacacgcat cgcgcaaaaa tggcttagca
    10381 gcaaagcagc aaaagtcgag ctgatccctt tgaaaaataa tcagcaggct ggtagatacc
    10441 ttgacttgaa agtaagtatt caatatgatg aatggggcta tgatgatatt ttgaattttc
    10501 gtctgccagc agatgttcaa aaacagatcg aaggagaaaa aatcgaactt ctcgattggg
    10561 tgaatgaaaa tctggaagaa acttacgttc atgaggcgaa tggggaacgt gaagaacaac
    10621 gaaaggattt ttcaagtgaa taaattttta ggatttggag cagttgtgat tatgatcgca
    10681 gcaatgggct atgttatttt tagcgatgat gattcgcatg ttcaagccgg caatcaagca
    10741 gtcgaacgaa caagcaccaa aacaactgct agtaaagaaa agaacagtca aacaaccagc
    10801 agcaaggtaa aggacaaaga aacaaaagat cgtacgtcca aacaattgcc agatgttaaa
    10861 acagacgatt ggaagctagt tttggttggt ccagatcaca aattagaaaa agaaattgat
    10921 gagtctactc aattggcatc attaagtaac ggatacttga tcgacaaacg cattgctcca
    10981 gaatatgaag catttgccaa ggctgctgaa gcagctggat ttccattagt gatggtctca
    11041 gcttaccggt ctgtatcatc ccaacaacaa gttttcgaac aaaatgtcca agatgtgatg
    11101 agtcgtcaag gtgtatcaga agaggaggcg acaaagatta ctaaagaaac gattacggag
    11161 ccaggataca gcgaacacca cacaggtctg gcagtcgatg tcgtcgatca aaactggtac
    11221 aacagttatc cttctactgt attggatgca agttacggag atcagcctgg agctaaatgg
    11281 atcgcagata atgctgcgca gtatggattt atcgttcgtt atccaaaagg acacgaagat
    11341 ataactaaga tcacatatga accttggcac ttacgttatg tcggtaaaga aaacgctgag
    11401 tatatcacca aacaccaatt gacgctagaa gaatatctga atgaattaaa tgaaaagtag
    11461 gaattgatca tggcgaaaaa aaagtggaaa aagcaaaagc gcaagaatat ccgttggcca
    11521 gcagtggttg ccggtgtagc agtgatactc ttagcctttg ttttttcctt gaagaatctg
    11581 tcttctcctt ttactgataa tcagcaagaa aatgaagcgc aatcccatca gcaatttatt
    11641 gaacggcttg ttccgcatgc ccaagaacta caagatggtt atggagtgct tcctagtatc
    11701 attttaggac aagctatatt agaatcaaat tggggaaaaa gtaccttggc tagcaaatac
    11761 aataatcttt tcgggatcaa ggcttatggg gatcagaaga aagtaagcct ggaaacaaag
    11821 gaatttgtta acgaagaatg gataactatc caaggagact tcaaagtgta tgattcatgg
    11881 gaacagtcca tggatgacca tacacaactg ttcgtccaag gagtagattg gaatcctgcg
    11941 ctgtatgaaa aagtgattac ggccaccaac tatcaggaag ccgcacaagc attgcaagat
    12001 gcaggttatg cgacagaccc cggttatgcg caaaaaatca tccaggtcat cgagacgtat
    12061 caattgaatc agtatgaccg gagatagcaa aggagaagtg gctgatggca gaacaattta
    12121 cgccagaaat catgacggaa ttgagaaaag atatcgtaag agtaccggaa atcattttag
    12181 aagcaagcgg gatcaagata tttggaaaat tgatccgttc gatcatcttt actacggata
    12241 ttgcgatcat acgtaataca aatgcgaatg cagtaattgc tgtgtatcct tttacacctc
    12301 atccagcgat tactaaaagc attattgagg cagctgacat tccagttttc tccggtgtag
    12361 gtggtggttt gacacaaggt gctcgttctt cctacatgag catgttcgca gaagcgcaag
    12421 gttcgttagg ggtcgttttg aacggtccta cgcctttaga gacagtaaaa gaagtttgtc
    12481 gagtagttga tattccagtt atcagtacgg taacgtcgaa atatacagaa atagatgaaa
    12541 agttagcagc tggtatttcg attatcaata tcagtgcagg taaagaaact gcagaagcag
    12601 tacgccattt tcgtaaaaaa tatcctgaac ttcctatcat tgcgacaggt ggtccaacgg
    12661 aagaaagtat tgctgagacc attcaagcag gagcaaatgc catcacatat acgccaccaa
    12721 gtagcggaga gctttttagt cgtaaaatgg aaaaatatcg ggaaactgag aaaaagaatc
    12781 atgaataaca ggtgagaatc aaaagacgag gaagagcaga tagtggctct tcctcgtctt
    12841 ttgtactcca gtactatttg ttcagaattc aaaaaaaaga gaaatttttt tgttttttta
    12901 cctgtaatgt acataagaag agttaaaacc ttttgttatt attagcattc taacaaaaaa
    12961 atgtcttgat ttattgaagc gctttctata gaatgaaaaa cgaataaaaa ctaaaaaagg
    13021 cacccgacaa tttagtagca gctaaattgt cggggcttga aaagtcagcg ggaactgacc
    13081 aatcaagttg ccatagtcaa tgcttgtgca tcgacgtgta tattgtacct aatttcatac
    13141 agaattacta gttatttttc tgttttttag ggaagagcgc acacgaagaa gcatgcttat
    13201 ttagctatgt caaggatatt gggcagttgt ctgatatcct tttttctttg cgtaattatc
    13261 ctcccatcat tgaagcaaga agtgttttta gcgatgaaag aagaatcagc actatctaat
    13321 ttttcttgaa agtattgagt tgttcatcct aggcagaacg ataaggcaag tcttggtttt
    13381 tattcccctt gaaaaagatc gtttaataaa tatgttctgt ataaaaatac agtatattga
    13441 aaaataacaa tggaagtaga ggtgcagaga atgaagaaaa gaatgagaat catcttagct
    13501 ttaagtgtta tgttattctt cttgacggct tgtgggcaag aagatgacaa aaaaatcacg
    13561 ctgaacatgg cttggtgggg ttcgcaagtc cgacacgatg caacagtaaa agtaatcgag
    13621 ctttatgaag aaaaaaatcc ccatgtgacg atcgattatg aattttatga ttatgaagga
    13681 tattacacaa aattaggtac actagcagca tcagatgata tctgggacat tttccaactg
    13741 aacaatcaat ttcctcaata catcaatcag attgaaccat tagatgaata tgtggagcaa
    13801 gggataattg atatttctaa tgcagatgaa tcctatttag caacgacgac ttacgacggg
    13861 caattagttg gactgtctaa cggggtgaat tcgtttgcga ttgcttacaa taaaaatata
    13921 tttgaacaat taaatatccc tgaaccagct tcaaattgga catgggatga atttgaacaa
    13981 atcagctatc aaatcactga agaattagga atctatgcta tttcaagatt cgaagatttt
    14041 atagctggct gtattattca aataccacaa gttgagaaag gattgaattt ttataatcgg
    14101 gaagatctat ctaacagctt gggatttgaa aatccagact atctaacaga ttttttccag
    14161 ctgcgtaaaa atctggtaga caaaggggcc catccagaac caggtggtgg agctgcaagt
    14221 acgacggatc tgtcttttca ggcggttagg gatagagaag cggcaatggt gtttctatca
    14281 agtaaccagt tgacagaaat attgtcaggg gctcctgaag atatggagat tcagttgatt
    14341 aatccacctc gcagaaaagc agatggagaa tctggtatcc ctttacgttc ttcgcaaatg
    14401 ctgagtatgg caaaaagctc agcccataaa gaagaagctg ctaagtttat tgatttcttt
    14461 caaaacagtg aagaagccaa tgaaatttta aaaggagaac gtggtgtacc aatcatgtcg
    14521 aatattcgag aacagctcgc tcgtgcagat gatgcaactt tgcaagcgac atttgattat
    14581 ttagaaatga tttccgatat ggacaacggc gaagtgaatg tctttgatag tgctttgaat
    14641 ccggaaattc aagaccaata caatctttta gttgaaaaag tcatttatga agaagtaaca
    14701 gcagaagaag cagcagagag tctttatgag tttgcgtcaa acattctagg atagcagcag
    14761 gaggaaggca tgaaaaaaga aaaactaaaa cggttcttgg atcaagacaa tgtggtcggt
    14821 tacgtatttg cttctccatt catcctagga tttctattga taacagtgat accgatgatc
    14881 ttgtcacttt attattcgtt caccgattat cgtttgggaa atccagtctc atggatcggc
    14941 ttggataatt atataaagat gctgagtgat gcccgttttt tgaactccat ccgagtcact
    15001 tttctctatg tatttgcatc tgtacctgtg aaactgatct ttggtctatt gattgcttat
    15061 cttttaacga ggaatatcaa aggaacgact ttctttcgtt ctttgtatta tgtgcctagt
    15121 ttgatcggtg gcagtatttc tatcgctcta gtttggcggg agttgttttc taaaaacggg
    15181 ttagtgaata ttttcctgga acgattaggc gcacctgcgc tttcctggtt tagcgatcaa
    15241 aaactggtca tgatccctct tgttttgatg tctgcttggc aattcggttc ggcaatgatc
    15301 atctttgctg caggtatcaa agagatccca ggctcgtatt atgaagcggc agagatcgat
    15361 ggagcgaaca aatggcagac gttttacaag atcacgttac ctcttctttc gccgatcatt
    15421 ttgtataact tggttatgca gacaatcgcg gcgtttatga cttttacgca ggcatttatc
    15481 attacccaag gtggtccgaa tgatgccacg aacttttatg ctctttatgt gtataaccaa
    15541 gctttttctt ttaattctat ggggtatgct agtgctattt cgtggatcat gctgttgatt
    15601 atgggagctg tcacctttct gattttcaaa tcatcaaaaa aatgggtcgt tgtgtgaatg
    15661 agaggaggaa gaaatgaata atacagtaac gaaatggttt caatacggtt ttattttgct
    15721 attaggtcta gtcatgattt atccggtctt atggatgatc gcaggttctt ttaaaacgga
    15781 tcaagagatt atgagtggtt cgctgaattt gattccagag acttttcaat gggaaaatta
    15841 cgcaaaagga tgggcggggt ttgctggaat ttcatttttt actttcttta ggaattcgtt
    15901 tgtcatctct gcagtttcga cgatagggac agttctgagc tcgacttgta ttgcttacgc
    15961 attatcgaga atcgatttca aaggaaaaag attctggttc gtcgtcatgt tagtaacgat
    16021 gatgattcct gcacaagtga ttttgattcc gcagtttatt atttacaatc ggctgaattt
    16081 ggttgggacg tatgtgccgc tgattttacc acattttttt ggacaagcat ttttcattta
    16141 ccagatcatg caattcatgg tcagcatccc caaagagtta gatgaatcag cgattattga
    16201 cggatgcagc aagtatagtg tctttaccaa aattattttt cctttgctga aaccttcgat
    16261 catcacgacg atcatcatcc agttttattg gaaatgggac gacttcatgg gaccattgat
    16321 ttatttaaac aagccgagat cttacacggt atcgattgcc atcaaattat ttgcagacgc
    16381 tggatctagt acgacttacg cgagtatgtt tgcgatgtct acgttgtcgc tgctaccggt
    16441 ttttctgatt ttcttattct tcaataaata tcttgtccag gggatcagta caagcggtct
    16501 gaagggctga atatgaaaaa gccaatagaa gagatgtttc tttacaagct caactactat
    16561 gtctgtcgga tttttttaac cagtcttatc agtaatgctc ttttcgcttt agttctagga
    16621 tgtttgttca ctttaggatt agtgctgtct gctcgtgttg tctatctgat ttattttttg
    16681 atgatgtatc cttcttatta tctatctgtc cattacttgg cagaaaaaaa ggtatgttgg
    16741 aggaaaggaa aaatcaaacg gatgtgtttc atcattacgt tgtttcagct gtttgtcatt
    16801 atttttgcag ttgattggta tttattagtg ggaaagattg gagcttggta tctgattcct
    16861 tttctattgt gtctgttgct ttttgtatcc catagttttt ttagtacgct aattgatatc
    16921 tgcaaagaag ataaagcaga tagtcttgtt tatttgatca aaaggaatat ctggctgttg
    16981 tcaaaaaacg tcaaggggtt tctgtggtat ttatgccttt tgtatggact gttctggtgt
    17041 atacagcatg attttttact cactgcatta ctgtatccag ggctgccatt tgtcacagta
    17101 ttttgcttaa aagaaaagga gaatgacttt aaatgaagaa aaaatatgta caagtcggac
    17161 ttggtgggag agcgcgtttt ttttatgagg caattgcctc tacgtatcat caaacttgtg
    17221 aactagtcgg tttttgtgat gtatctcaaa caaggatgga ttatgcaaat cggatacttg
    17281 tgaacaagta tggacagaaa aaagtaaaga catgtatgcc atcacaattt gagcaactac
    17341 tggatgacgt acggccggct gaagtcatta ttacgtcagt agatcgaacg catcatgatt
    17401 atatcattcg tgcaatgaaa aaaggatatg atgttatttg cgaaaaacct ctgactatcg
    17461 atgaggaaaa agctcaagaa ataataacgg tccaaaaaca gacgggaaga agcctgcgag
    17521 tcacttttaa ttatcgttat gcaccgtatc acacgaagat aaaggaactg atagaaagtg
    17581 atgtgattgg tgatgtgttt tctatccact tcgaatggct gttaaatacg caacacgggg
    17641 cagattattt cagaagatgg catcgaaata agcacaatag cggcgggctt cttgttcata
    17701 aatctaccca tcattttgat ctagtgaatt tttggttgaa cagccgtccc caaaaggtat
    17761 ttgcattcgg tggattaaac ttttatggga tgcataatgc ggagaaacgc ggagtagaaa
    17821 tattttacag tcgatgctat ggaagcgaac tagctaaagc tgatccattt gctatagacc
    17881 tgtcagccaa tgaggaattg cgagaaatgt atttagaagc agaaaaagac agtggatata
    17941 ttcgtgaccg cagtgtattt tccgatgata tctctattga agatacacta ggcgtaacgg
    18001 tcaaatatga aactggtgcg attttgacgt attcgctaaa cgcgtatatg ccgtgggaag
    18061 gattcaatgt ttctttcaat ggcagcaaag gacggatcga aatgaaagtg atcgaaaagt
    18121 cttacatcaa tgcaggtgga gataaaaagg atgaaggagc agccgttctt cagtccatcc
    18181 atgtctatcc gatgttcggt gagccatatg aggtaatcgt cgaacaagaa gcgggcggac
    18241 atggcggagg agatccgcgt ttattagatg atctatttgg tgaagaaaaa gaagaagatc
    18301 cgtggaatcg ggcagcaact cacgtagatg gtattttgtc gattttgaca ggaatcgcag
    18361 caaatcattc tattgcttca ggaaaagcag tagtgattga cgagcttgtc agcttaaaag
    18421 aataagaata gatttacgga aattacttcc cgtagtttat aaaatcttgc cttattgccg
    18481 ataggctgtc ttttgaacac tatttattcg gaaaaagggg ctatgacatg ctttttgtca
    18541 tgccttcttt ttatgtgggc tgctttttta gataggagaa aataaaaata actatttaaa
    18601 cccgaacaaa aaggaataat gcattaaaaa tcattagatt ttacaaaaaa ataagtaaac
    18661 cacgttgtca gtttcagaaa gtagtgttag actgttttca atatttgaaa caacattttt
    18721 tattcaaata tggcaaactg ccttcacgtg caaaacagtt gcaagaaaat gaatttacac
    18781 tattattagt tttacatacc tacttatata tcgtcataat atggatgaca gtttctagcc
    18841 agtaccgtaa atgctggact ataagtaaaa gattggctat ttcacccttc ttttcttatg
    18901 ataaagtgga gggtgttttt ctttaacaga aacatagtag gtttttgcac aaaagcggtt
    18961 atttcggtat taataaatga taaaggagca aataaagtga aagaattagt tgaacgtatt
    19021 caaaaagacg gacgtatatt aggcgagggc gtattaaaag tcgacagctt cgtcactcac
    19081 caagtagacc ctgtattgat ggaacaaatg ggaaaacggt ttgcagaagt atttaaagaa
    19141 caaggaatca cgaaagttgt gaccattgaa gcttctggga tcgcaccagc tttatttgct
    19201 gcaagagaat tagatgttcc aatgatcttc gctagaaaag caaaaagttt gacgatggat
    19261 gaagaattat tgacagcttc tgtttattct tttacgaaac aagtgacaag tacgatttct
    19321 atttctcgta aatttttatc ttcagaagac aaagtattga ttatcgacga tttcttggca
    19381 aacggacaag cggcaaaagg attgatcgaa ttatgccagc aagctggagc gcaagtagaa
    19441 ggaatcggga tcgtcatcga aaagtctttc caagatggac gtcagttact tgaagaaatg
    19501 ggattgagag tcgtttctct tgcgcgtatt gcttccttga cgaatggaca agttgagttt
    19561 cttgaggagg acgcataatc gtggaaaaag aaacacaaaa tggaaaagct gcggttttag
    19621 ggctgcagca tctgctagcg atgtatgcag gagcagtagc ggtgcctctt ttgatcggta
    19681 caggactagg ctttaatcaa gaacagatga cttatttgat ttcaattgat atctttatgt
    19741 gtggattagc gacattattg caattgacag ttaaccgatt tttcggaatt ggcttgcctg
    19801 tcgttttagg atgtgcgatc caagcagtag ctccactgat cttgatcgga accaatgaag
    19861 gagtaggagc tatctacgga tctattatcg cttctgggat ctttgttgtg ttagtttctg
    19921 gtgtcttttc taaaattaaa aaactattcc ctcctatagt aacaggaacg gttatcaccg
    19981 ttattggttt gactttgatt cctgtagcaa tcgagaaaat gggtggaggt aatgcaacag
    20041 cagctgattt tggtgacaaa acaaatctgc tacttgcatt tgtgacgatt ctcctaattg
    20101 taggcgtgca aatgctggca aaagggttca ttcgttcaat cgcggtattg attggtttag
    20161 tcggaggaag catcttagct gctttcatgg gaatgattga tctgagcgcg attggagatg
    20221 cgccgttgtt ccatgttcca caaccctttt attttggtaa accaactttc gacgtatggt
    20281 cgattttact aatgatcatc atttccatgg tcagcatggt agaatcaaca ggtgtatatt
    20341 ttgcacttgg tgacattact gggaaaaatg ttggagaaga agaattgaaa aagggatatc
    20401 gtgcagaagg acttgccgtt atcttaggcg gtattttcaa tacattccct tatactggct
    20461 tttctcaaaa tgtcggattg gttcaacttt cgggaatcaa aacaagaaaa cccatctatt
    20521 tctctgcatt cttcttgatt gttttaggat tattccctaa aatcggtgcg ttagcacaaa
    20581 tcatccctga gccggtactt ggtggaggaa tgttagtcat gttcgggatg gtggcagtcc
    20641 aaggaatccg tatgctgttg gaagttgatt tcagcaatga taaaaatcta ttgattgttg
    20701 ctgtttctgt tggatttggg ctgggtttca atgttacgcc gacattattc agtcaaatgc
    20761 cgcaaacatt gcaaatgttc actggaaatg gcatcgtaat gagtagcatt acggctatca
    20821 tattgaattt gatctttaat ggattgaaaa aagatgaaga aatattggaa gaagccttca
    20881 agaagtaata gagcaaaaga aaggttgtga aatcagcgtt ttgacctgat tgttagagaa
    20941 acaaacggaa aaatagttcc tcgtattttg ccgtttgttt gagctaatac cgagggtcag
    21001 ctgattgaac accgttgaag gaagaggtcg tgagcctgcc gttcatctcc gagtcacaag
    21061 gaacaatttc aaaaaaaagc ttctcatgtt tgttgaatat tgttccttgt gaccgaggag
    21121 ttggcaggag aacaccgttt atccataaaa aggaatgtga cctaactttt gtcacattcc
    21181 ttttttttat ctttaataaa cacgaacaat aaaatgtttt tctttgttaa cattcgaaat
    21241 ttctttgaca tcaaaaaaag tgattgttaa aatatgaatg tagaaaaact gggaggaaaa
    21301 acaatgacag caaaaatctc tgtgattatg gggagtactt cagattggga aacaatgaaa
    21361 gaagcatgtc aaatattgga tgaattcggt gtgtcttatg aaaaaaaggt cgtttctgct
    21421 catcgaaccc cagatttgat gtttgaatat gcacaaaacg ctcgaaaaaa aggaatcaaa
    21481 atcattattg caggagcagg gggagccgcg catctgccgg gtatggtcgc atcaaaaaca
    21541 actttgccgg ttatcggtgt accggtccaa tcacgaacat taaatggttt ggattcgctt
    21601 ctttcgattg tccaaatgcc tggaggagta cctgtagcta ctacagcaat cggaaaagcg
    21661 ggagcaatta atgctggact acttgcgata cagatgcttt ccatgtatga tttagaattg
    21721 gaggctaaat tggctgaaag acgttcaatg ttggctaaaa ctgttataga aagtagtgat
    21781 caacttggtt aaacctttgt tgcctggttc aacgatcggg atcgtcggtg gcggtcaatt
    21841 aggtcgtatg atggcgatta gtgcaaaaga aatgggcttt aaagtaggtg tgctggatcc
    21901 tgtgagcgat tgtccagccg cacaagttgc agattggcac attgaaagtg tctatgatga
    21961 cacctttgcg ctgaaagagc ttgccagaag aacagatgtc attacctatg aattcgaaaa
    22021 cgtcagtgta gaggcgttaa atgcgatttt acccatgtca tttattcctc aagggacaga
    22081 cttgcttgcg attacgcaag accgcctgtt agaaaaatct tttttggaaa cgaataacat
    22141 cgtgattgct ccttatgcaa cgatcgtcag tccgacggat atccaagatg cgattgacgg
    22201 gatcggctat ccttgtgttt tgaaaaccac tcgaggcggc tatgatggca aggggcagta
    22261 tgttttgaaa agtcgggcgg atctagctcc tgccatggac cttttaagag aaggaacctg
    22321 tgttttagaa gcatggatcc cgtttgaaaa agagatttcg atcatggtgg caggaaatgg
    22381 tcaaggagat ttcacgactt ttccggtcgt ggaaaacatc caccacaaca atattcttca
    22441 tgaaacgatt gctccagccg cgattgatca ggatgtgatc gaggaggctg agcgtattgc
    22501 ccgtgtgatt gcagaagcag tgagcctttc aggtgtttta ggggtagaaa tgtttttaac
    22561 aaaaacaggc gggctatatg tgaatgaatt agctcctcgt cctcacaatt ctggacatta
    22621 ttctattgaa gcttgttcta tgagtcagtt cgatgcccat attcgaggta tttgtggttg
    22681 gccattagga gaaaaagtac gtttgataag caatgcagta atggtcaatg ttttgggaga
    22741 acaactgctg gaaagctatc gcttgattga gaataagcca gactggcaat tccatttcta
    22801 tggaaaaaaa caagcaaaaa aaggtcgcaa gatgggacat atcactatct tgacagaaga
    22861 catccagcaa acgctggaag aaatcaaaca aacgaatatt tgggattaga ggagaaaaaa
    22921 catgttagaa cgttatacac gccctgaaat ggggaatatc tggacggaag agaacaaata
    22981 ccgtgcgtgg ctcgaagtcg agattttagc agatgaagct tgggcagaac ttggtgaaat
    23041 cccgcaagaa gatgtgaaaa aaattcgtga gcatgcatca tttgatatcg atcggatctt
    23101 ggaaatcgaa aaattaacac gccatgatgt cgttgcgttt acacgagcgg tttctgaaac
    23161 attgggagaa gaaagaaaat gggtccatta tggtctaaca agtacggatg tcgtagatac
    23221 tgcttatggc tatctcatca agcaagcaaa tgatatttta cgggaagact tgaaacgttt
    23281 tacggaaatc attggcgaaa aagcaaaaga acacaaatat acagtgatga tgggtcggac
    23341 acacggtgtc catgctgaac caactacttt tggattgaaa cttgccacat ggtattcaga
    23401 aatgaaacgg aacatcgaac gatttgaaca tgcggcaaaa ggagtagaag caggaaaaat
    23461 ctcaggagca gtgggaacgt tcgcaaatat cccgccattt attgaagagt atgtatgtaa
    23521 acaattgggg atccgtccac aagaaatctc tactcaagtt ctccctcggg atctacatgc
    23581 tgaatatttc tcagcgatgg cgcttattgc tacaagtatt gaacgttttg caacagagat
    23641 acgcggattg caaaaatccg aaacacgtga agtagaagaa ttttttgcga aaggtcaaaa
    23701 aggttcttct gctatgccgc acaaaaggaa tccgatcggt tcagaaaata tggctggtct
    23761 agccagagtg gtgcgcggac acatggtcac tgcctatgaa aatgtcacat tatggcatga
    23821 aagagatatt tctcattctt cagcagaacg aatcatcttg cctgatacca cgattttatt
    23881 gaattacatg ttaaatcgtt ttggcaatat cgttaaaaat ctaacggtct ttcctgaaaa
    23941 catgaagcgg aatatgtctg caacatttgg tttgatttat agccagcgcg ttatgctgaa
    24001 attgatcgat aagggaatga caagagaaga agcttatgat cttgttcagc caaaaactgc
    24061 gtacgcttgg gacaaccaag tgcagttccg cccgctgtta gaagaagatc caaccatcac
    24121 atcggtatta tctaaagaag aaatagacga tgcctttgat tatcatcatc atttgaaaaa
    24181 cgttgacgtg atattcaaac gagtaggttt ggaataaaga agagtgagtt gcaaaattca
    24241 attaaaatag aatagcaaaa ataatcgagt agaggggaaa gccaactgac cttccgcccc
    24301 tctcacacca ccgtacgtac ggacccgtat acggcggttc aataagttga gtgtacgaac
    24361 tggtacttca aggagatgtc ctcatatcct tggcgggcca gttctttgtc tgttaatgat
    24421 cgatgaagaa tatgactttt ggagactgac caaatacctt ttcttgtatt tgaccattca
    24481 tacgctttcg ctttatcgat ccctaaacga atcagatttt ttcttttggt tcttggattc
    24541 ttccattgtt tccaaatata ttgtctgatt cttcgcttca accaaccgtt taactccctc
    24601 atgaattctt tcatctcacc aattccatag tagttgatcc aaccagtcat tagttgcttg
    24661 atttctttta aaataagttg gatacttctt ccacggtttc ttttagtgag ttgtttgagc
    24721 ttgcttttca cacgctgttt tgcttttgcg tgagggcgaa ttttaatacc tttctttgtt
    24781 ggcagaatgc agaatccaag aaactttcgt ttcaatggac ttcctaccgc actcttttct
    24841 cgatttaccg tcaactttag ttgttcttcg agaaattgaa tggatttctt catcacacgc
    24901 tgtcctgctc gtttgcttct aacatagata ttgcagtcat cggcgtatcg aacaaattta
    24961 tgtcctagat tttctagcac ttgatcaaat tcgttcaggt agatgttact taacagggga
    25021 gagagattgc ctccttgggg cgttccttct tcagttgttg tgatgagtcc attttccatt
    25081 acaccactca ttaagtattg acggatcagt tttaggactt gtttgtcctt tactttccgc
    25141 tcaatgaaat acatcagctt atcgtgattt acggtgtcaa agtaggcttt catatcaatg
    25201 tccaccacat atcggtaacc ttgttcataa taagattttg ctttcttcac tgcgtcatgt
    25261 gcgctgcgat ttgggcgaaa cccataacta ttatctgaga attctggttc aaatagcggt
    25321 tgtaacactt gattgattgc ctgttgaagc atacgatcaa taaccgtggg aattcctagt
    25381 tttcttacac cgccgtttgg tttcggtatt tctactcgca aaacaggctg aggtttatag
    25441 ttcccttggc gtaaattgga tagtaattcc tcgcggtgct ctttcaagta aggaagcagt
    25501 tgatcgacgg tcatcccatc tgcaccagcc gcccctttat ttctgactac ttgaagatac
    25561 gcttgattga gattattccg atctagaatt ctcccaaaca gattttctac accatcttgt
    25621 ttcctctgtt caccgcaaga agtgctgcgc acttcatcat acccttcgtg ttccacacta
    25681 gctctttgat gatagccaag ttttcttgtt ttctgcggtc gtcgcatctt ctcacacctc
    25741 ctaaattatt caagattctt attgttcagt ccttcgtaac ggtcagtgtc gttactacta
    25801 tgacctcggc tgacttctca tgattcacca tcatgtcgcc atgatcgttg tgctggtttg
    25861 ttttcattca acgcccacaa caccctcatg agatctcccc cggtaagagt gaaaactttc
    25921 ctcccatgta actgctagat ttactgtata ggtttcgggc agtattggac tttgtcttgt
    25981 gatgaagact tatccgacct aattcagcct tgtatctagt ttctgttcgt cagttcagga
    26041 gtttgcgtcc gacttccttc agccacaacc tcacgattgc cgccttgtct ttcgctaaca
    26101 gttcctactg ccaagcctgt agtggacttt caccaccaag ttttcaccca tgcagggcgc
    26161 acaccaaaaa agaagcagat ccgttagcgg ttctgcttct tttagtttat tatattttct
    26221 tatcaataat aggaacctga ttttaaaagc ggctacctct ttaccgtgcc tctttacata
    26281 caaaaaatag aggaattaag cgtaaatggc ttggctatta taactaaaat gctggttatg
    26341 gagatgttgc agcaagtttt cgagaaaagc gtattccatc tcttgtccat tgaataagat
    26401 ctggatacga taatgatttt tgaaacgctt ctgttcatga atctgactga ttgaaagttc
    26461 gcctttgtgt tctgtctgat aaagaaaagt ccttttacgg cattcagcac agcgcttggt
    26521 tgctcggcgg atttttcgga atgtataaaa actagtatct ttattgcata aataaacgtc
    26581 tttgatcgac agcaaatcat tatatagaca ggaacgttct tcagctgtta attctgataa
    26641 aaaaagctga ccttgtttta ttgcatcttc catcggcaag tgcctcctcg aacccattat
    26701 ccaaattttt agttaattct aatataccat cattaagtat aaatgtaaac gcttgttgat
    26761 ggtataagat tttcgtttct gataaaacac gaacattaaa agaatctaat gccttaaatg
    26821 tacatatttt tgttgattta taaaaagatg attgctaaaa tttaaagtga aaaaacgaac
    26881 aaaaaacgat gtatttgctt ttaatgtaaa taaaaaggag aggcgtacat ggagaagaaa
    26941 gaacttttgt atgaaggaaa agccaaaaaa atatatctta cttctgatga gaacttgatt
    27001 tggatagaat atttagatca agcaactgcg ttgaatggcg cgaggaaaga ccagataagt
    27061 ggaaaaggag aattgaataa tcaaatcaca agtgcaattt tccgttatct gactcaaaga
    27121 ggaataaaaa atcattttat tgaacaattg tctaaaaccg aacaattagc aaaaaaagta
    27181 caaattatcc ctctggaagt ggttatccga aatattgcag caggaagttt ctcaaaacgt
    27241 ctaggtgttc ccgaaggtaa agaattcatc aaaccaatca ttgaattcta ctataaggat
    27301 gaccagttgg atgatccatt tatcaatgaa gagcatatct atttcttaca acttgcaaag
    27361 ccggaagaaa tcagtgagct gaaagcccaa gcgttggcta ttaatgaaat tttgaccgaa
    27421 ttatttgcta aggtcggttt ggttttagta gatttcaagc tagaatttgg ccggtcgaat
    27481 ggacaaattt tgcttgcgga tgaagtaaca ccggatactt gccgattatg ggatgaacgt
    27541 acgaatgaac atatggacaa agacgtttac cgcagagatc taggtgattt gatcccagtc
    27601 tatcaagaag tatataaccg tctatcggaa ctaactgaag aaaaggagcg agtatgatgt
    27661 atttcgtaaa agtatatgta acctataaag attcagtgtt agatcctcaa ggggaggcag
    27721 taaaaaaagc agtccatcgt atgggatatg aaacaatcga agatatccga ataggaaaat
    27781 actttgagat acaacttgct gatgcagaag aaccaatcga tacagtgatt gaaacgattt
    27841 gtgacaagct gcttgcaaat gtaaatatgg aaacataccg atatgaaatc aaaaaaatgg
    27901 aggaagtata acatgaaatt tgcggtcatc gtttttccag gttcaaattg tgacgcagat
    27961 atgttatggg cagttcgcga gatcatgggc gctgatgccg aatttgtacg gcatgatgag
    28021 tcctctttag aaggatttga tggggtttta ctgccgggag gattctccta tggtgactat
    28081 ttgagatgcg gtgcgattgc tcggttttct acaatcatgg aagaagtgat tcgttttgct
    28141 gaagaaggga aaccagtatt cggtacatgc aatggattcc agatattgac agaagcagga
    28201 cttttgccag gtgtactgag acgaaatgag tctttgcatt ttatttgcaa aactgtacca
    28261 ttgaaagtca accccaagac ggcctttact tcagagtatg aagccgacga aataatctat
    28321 cttccagttg ctcatgggga aggaaattat ttctgtgacg aagaaacact tcaagaacta
    28381 aaaaaaaata atcagattgc ctttacttat aatgacaaca tcaacggcag cgtggaaaac
    28441 attgcaggga ttacgaacaa agcagggaat gtgttaggaa tgatgcctca tccagaacgt
    28501 gcagtagaag acttgctagg atcagaagat gggaaacggt tctttgcttc cattttaaaa
    28561 aacttcggaa aggtgaccgt atagatgaaa acattgaaag aaccgacagc tgaagagatc
    28621 aagaaaaaaa gaatctatgc cgaatgggga ttgactgatg aagaatatcg aatgatcgaa
    28681 gaagatatct taggaagaat gcctaattat acggaaactg gactgttttc tgttatgtgg
    28741 agcgaacatt gttcctataa aaattctaaa ccggttctac gcaaatttcc tactagtgga
    28801 cctcatgtgt tgcaaggccc tggagaaggc gcaggcatcg tcgacatcgg tgatggacta
    28861 gcagttgtct tcaaagcaga aagtcacaat catccttcag ccgtggagcc ttatgaagga
    28921 gctgcgacag gagttggcgg aatcatcaga gatattttca gcatgggggc tcgtccaatt
    28981 gcgttgctag attcattgag gttcggcgaa ttagataatc caagaacgaa atatttacta
    29041 gaagaagtag ttgcaggtat cggcggatac ggcaattgta tcggcatacc gactgtaggc
    29101 ggcgaaattg catttgatcc ttgttatgaa ggaaacccat tagtcaatgc aatgtgcgta
    29161 ggtttgattg aacacaaaca tatccagaaa gggcaagccg ctggcgtcgg taattcgatc
    29221 atgtatgtag gtgcaaaaac aggtcgcgac ggtatccacg gagcaacttt tgcctcagaa
    29281 gaatttaatc aagaagaaga acagcaacgt tctgctgtac aagtaggcga tccttttatg
    29341 gaaaagctgc tgcttgaagc gtgtttggaa ttaatcttgc atcattcgga ttctctaata
    29401 ggtatacagg atatgggagc agcaggactt gtttcatcta gtgcggaaat ggcttcaaaa
    29461 gctggctcag gacttatatt gacattagat gaagtcccac aaagagaaac tgggatgaca
    29521 ccttatgaaa tgatgttatc ggaatcacaa gaacggatgt tgatttgtgt taaatcagga
    29581 gaggaagaaa aaatccaaga actatttcag aagtatgatc tagatgcagt cactatcggt
    29641 aaagtaacag acgacgggca atatcggcta tatcatcaag gagaagaagt agcaaatctg
    29701 ccagtcgatg cattagctga agatgcacca gtttatcata aagaaatgaa agaaccagct
    29761 cgaatcgtag aatttcagca gttagctcct tatcagccag ttatcgaaga acctggacaa
    29821 gtattgcttg atctgctgca gcaaccgacg attgcttcaa aacgttcaat ctacgaaact
    29881 tatgattcac aagtacaaac caatacagtt gtccgtccag gaagcgatgc tgctgtgatg
    29941 agggttagag ggacgaataa agcgttagct atgaccacag actgcaacgc gcgctatctg
    30001 tatttggatc caaaaatcgg aggacaaata gcagtggcag aagctgctag aaatattatt
    30061 gctagcggtg gtaagccctt ggcgatcacc gactgcctga actatggttc tcctgataaa
    30121 ccagaagttt tttgggaatt atcgacttca gctgacggaa ttgctgctgc gtgtgaaacg
    30181 ttaggaactc ctgttatttc aggaaatgtc tctttatata atgaaacgga tggtcaagca
    30241 atctatccaa caccaatgat tggtatggtc ggattgattg aggatcataa acatatcact
    30301 actcaggaat tcaaaaaatc aggggatcta atctatatat taggtaagac gtttgcagat
    30361 tttgatggca gtgaattaca aaagatgcag cttggaagaa tcgaaggtgt gatccgaaac
    30421 tttgatctat ccattgaaaa gagaaaccaa gagttagtat tgacagccat ccaaaacgga
    30481 ttgattgaaa gtgctcatga ctgttcagaa ggtggcttgg caattgcact ggcagaatca
    30541 gctttcaaac atcagctagg gatatctgta cagtttgaat tgtcctctgc tcaattattt
    30601 gcagaaactc aatcaagatt tgtgttgaca gtcgcaccgg aaaataagac acgattcgaa
    30661 gaaatgatgg gagatgctgc tgttttagca ggtaaggtga cggatgaagc gataatcgaa
    30721 atttcagcaa ctgacggtca gatcaaaata gaaactgcag tagcaagaaa gtgctgggag
    30781 gatgcaatcg tatgtcttat gaagtgaaga gtttaaatga agaatgcggg atcttcggtg
    30841 tttggggtca tccagacgcc gctagtgtgg catacttcgg gctccatagt cttcagcatc
    30901 gaggacaaga aggtgcaggt atcgtgtcca atgatcgagg aaagcttaag gggcatcgag
    30961 atttggggct gctttctgag gtattcaaag atcaaagaaa attgcagcag ttaacaggag
    31021 aagctgcaat cggacatgta cgttatgcaa cagcaggcaa tggaagtgtg gacaatattc
    31081 agccttttct attcaaattt catgatcagt cgatcggctt agcgcataat ggtaacttga
    31141 tcaatgctcg ttcccttaga aaagagttag aggaaaatgg ggcgatcttc cattctaact
    31201 ccgatacgga gatattgatg catttgatcc gacgaagtga agaaacagat tttttaaata
    31261 aattaaaaag tgctttgaat gaagtcaaag gtggctttgc ctatttatta atgacagaaa
    31321 cggcaatgat tgccgctttg gacccaaatg gttttcgtcc attagcaatc ggacaaatga
    31381 aaaacggagc atacgtgatt gcctcggaaa cttgtgcatt agaagttatt ggggcacgtt
    31441 ttataagaga tgtccagcct ggtgagatag tgatcatcaa tgacgaagga atccagattg
    31501 attgctttac gaaggacacg cagctttcta tttgttcgat ggaatatatc tattttgcca
    31561 gaccagattc aaacatcgca gggatcaatg tgcatactgc acggaaaaat atgggacgga
    31621 atttagcgaa agaatcgcca gtaaaagcag atatggtcgt tggcgtacct aattcttctt
    31681 tgtcagccgc aagcggttat gcggaagcta gtggaatccc ttatgaaatc ggattagtaa
    31741 aaaatcaata cattgcccga acatttatcc agccaacgcc tgagctaaga gagcaaggtg
    31801 ttcgaatgaa attatctgct gtacgaggag tagtggaagg taaaaaggtg attatggtcg
    31861 atgattcaat tgttcggggt acgacaagca gacggatcgt ccatcttttg aaagaagcag
    31921 gggcaaaaga agtccatgtg aggattgctt ctcctccttt gaaatatcca tgtttttacg
    31981 ggattgatat tcaaacgcgt aaagaactca ttgcggcaaa tcacacgatt gatgaaatca
    32041 aagaatgtat cggtgcagat tctttaggtt ttttaagtga agagggtctg atcgaatcga
    32101 tcggtctgga aaaagatgct ccgtattcag gattgtgtat ggcttatttc aacggagatt
    32161 atccgacgcc gttatatgac tatgaagaaa aatatcagga atcactaaaa gaaaaagtat
    32221 cgttctttta aaagcagacc aagaagggag tatatgaatt caatggcaaa tgcatacgca
    32281 aaagctggcg tagatgtcga agctggatat gaagtagtag aacggatcaa gaagcatgtc
    32341 aaaaaaacgg aacgtttagg tatgatgggc gctataggag gattcggcgg ttgttttgat
    32401 ttatcggtct ttcaattaaa agagccagtc cttgtctcgg ggaccgatgg cgtggggacg
    32461 aaattagcag tggcaatcga agcagacaaa cacgatacaa tcgggatcga ctgcgtagcg
    32521 atgtgtgtca atgatatctt agcacaaggc gcagagccgt tatatttctt agactactta
    32581 gcaacgggga aaaatgatcc gttacgtttg gaaaatgtag taaaaggtgt agcagatgga
    32641 tgtgttcaag gaaatatggc gctgattggc ggagaaacag ctgaaatgcc tggtatgtac
    32701 tcaggtaatg attatgatct agccggattt gctgtaggga tagctgaaaa atctcaatta
    32761 ttgacaggag aaacgatcaa cccaggagat gtgttgcttg gaatagcatc tagcgggatt
    32821 cattcaaatg ggtactctct tgttcgcaaa attttctttg agcagcagca gttttcttta
    32881 tcatcaaaac tgccagaatt gaaaaaaaca cttggcgaag aattgcttga gccaacgaaa
    32941 atctatgttt cttccttgct tccgctgatc aaagaaaaga aaataaaagg agctgcacat
    33001 atcactggtg gagggtttgt agaaaatatc ccgcgaatgt taccagaatc tatggctgca
    33061 caaatcaaac ttggctcatg gccgattctt ccaatattcg gctgtttaca aaaatatggt
    33121 gaaattcctg agatggagat gtatgaaatc ttcaatatgg gcatcggtat ggtcctggca
    33181 gtccaagaat cgaaagtaaa agaaatagta cacgaaattg agcaagctgg cgaaaaagtt
    33241 tatgaaatcg ggaaagtgat cgccaaagaa aaacatcgtg tggtgtttat aggagaagaa
    33301 cgatgagaat cgctgttttt gcttctggaa acggaagcaa ctttcaagcg ctagccgatt
    33361 atctatcgaa aaaaggattg gaatcttcga ttgactggtt gttttgtgat cagcctgaag
    33421 catatgtttt gaaacgtgca actgcgttga gtgtaccggc agattgtttt tcacctaaag
    33481 aatttgattc aaaaaaagag tatgaagaag caattttgca taaattgaaa gaaaaaaaga
    33541 tcgatttgat cgtattagct ggatatatgc gaatcattgg accggtattg ctgaaaaatt
    33601 atgataaaag aatcatcaat atccatccgt ctcttttacc tgccttccct ggtttgcatg
    33661 gcatacgtga tgcctttgaa gctggagtaa aagaaacggg tgtcacaatt cattatatcg
    33721 accaaggtgt agatactgga ccaatcatcc ggcaggaaaa agtgagaatt gaacaggagg
    33781 acacgttcga ttctttagaa gaaaaaatcc atagagtaga gcatcgaatc tatccagaag
    33841 tgattagtga aattattgaa aatggaggct atctgaaatg acaagagcat tgatcagtgt
    33901 atcagataaa actgggattg tagcattcgc ccaaggtttg attgaacaag gagtagaaat
    33961 catttcaaca ggaggaacaa agcatgcgtt ggataaagct gggatcaaaa cgctttcgat
    34021 cgaagaagtg acagggtttc ctgaaatgat ggatggccgt gtcaaaacac ttcatcctaa
    34081 aatccatggt ggtcttttag gaagacgcga tctccctagc catatggagg caatggaaac
    34141 ggaaaatatc caaccaatcg actttgtttg tgtcaattta tatcctttca aagaaacgat
    34201 tatgaaacca gatgtcgaaa tagcagaagc tattgaaaac attgatatcg gtggtcctag
    34261 tatgctccgt agtgcagcaa aaaaccatga atttgtcacc tctgttgttg atccatctga
    34321 ctatgaagaa gtactttcag aattacgtca gtatgggcat acttcacttt ctttcagaca
    34381 aaaactagcg gcaaaagtct ttcgtcatac tgcggcatat gatgcactga tcgctcaata
    34441 cttaacggat tgggtggaag aaaaagaacc ggaaaaattg acacttacgt atgaacgaaa
    34501 acaaacgctt cgttacggtg aaaatagcca tcaagccgct gccttttatc agtccgctct
    34561 tctggaaaaa tattcgatcg cagcagcaaa acaactccat gggaaagaac tttcttataa
    34621 taatatccga gatgcagatg ctgcgctacg gatcatgaag gaatatgacg agccaacggt
    34681 agtcgccttg aaacacatga atccttgtgg tattgggaca gcatctacga ttttagaagc
    34741 gtgggaagca gcgtatgaag cagatcctgt ttcaatcttt ggtgggatca tcgttttgaa
    34801 tcgagaagta gatctgccaa cagcagaaca gatgcataag ctgtttctag aaatcatcat
    34861 tgccccttct tatacacaag aagctttgga attactgcaa aaaaagaaaa acatccgatt
    34921 actgacagta gactttgcgc aggaagaaaa tcaaaatcga gaagaaacgg tctcagtctt
    34981 aggtggactt cttgtacaag atcaagatct ggcaatagaa aatgaagaag agtggaaagt
    35041 cgtgacaaaa cgtaagccga ctccagcaga agcaaaagca ttagcgtttg cttggagagc
    35101 tgtcaaacat gtgaaatcta atgcgatcgt actggcaaac gaacgtcaga cagtaggaat
    35161 cggagccggg cagatgaatc gagtcggttc agtaaaaatt gcgattgaac aagcgcaaga
    35221 gaaaatggaa ggtgcagttt tagctagcga tgcttatttt ccaatggatg attcggttga
    35281 atatgcagcc aaacatggta taaaagcaat cattcagcca ggaggaagca tcaaagacca
    35341 agattctatt gatatggcga ataaatacga tctagcaatg gtctttactg atgttcggca
    35401 ttttagacat tagagaggag tcggataaat gaacattttg gtgatcggtg caggtggtcg
    35461 tgaacatgca ataagtaaaa aacttttagc cagtccgaag gtggatacgg tgtattgtgc
    35521 gccaggaaat ccggggatga caaaagatgg tatcaattgt gtcgctatca gtgagcgaga
    35581 tcattcagcg ttaatccatt ttgttaagaa agaggctatt gattggagta tcgttggtcc
    35641 tgaagttcct ttgttaaatg ggatcgtcga tgattttatg gcggaaggat tgaaaatctt
    35701 cggtccgaca aaagcagcag ctctgatcga aggttcgaaa agttttgcta aacaattaat
    35761 ggatacttat caaatcccga cagctaaatc cagaagtttt gaatgttacg aaaaagcagc
    35821 agcgtatatc aaagaaaatg gtgcgccaat cgtagtgaaa gcggacggct tagcagctgg
    35881 gaaaggtgta gtcgtggcta ccacagtgaa ggaagcgctg gatgcggcag aacaaatgtt
    35941 gaaccagcat cgatttgggg atagtagcaa aaaaatcgtc gtagaagagt ttttggcagg
    36001 agaagaattc tcccttttgg cgtttgtccg taataccaag gtgtatccga tggtcatttc
    36061 gcaagatcat aagcgggcat ttgataacga taaagggcca aatacaggcg gaatgggtgc
    36121 ttattcacca gtaccgcaaa tttcaaaaaa gatgattgaa aaagctgtgg aagaagtttt
    36181 aaaaccagcg gctttgggaa tgaaagaact aggacgctct ttcacgggtg ttttatatgc
    36241 gggtttgatt gctacgaagg aaggaccaaa agtgatcgaa ttcaatgcgc gtttcggtga
    36301 tcctgaaacg caagtcgttc tttctcggtt gaagagtgac tttgcgcaag taatcgatga
    36361 tttattagag aatcgtacag tagagttaaa gtggcagcaa gaaggataca atgtaggcgt
    36421 tgtggttgca gctgccggtt accccgaaga atatgagaca ggaatggttc taccagattt
    36481 tctggaagaa gagctttctg tttactatgc tggagtttcc tcaaataacg gcaaactagt
    36541 tggagcagga ggacgtcttt atttagtaga agcatacggt gagacgatca aagaagcaca
    36601 gaaaaaaatt tacaccgcgt taatggataa aacgacagat ggaacatttt atcgtacaga
    36661 tattggagaa aaagctgcca atagcgaact gatcgtgaag taaatcagct gcttccattt
    36721 ataaaaaata caacaaacat aatcggaagc gccgatttta gtgaagcctt ttcataaaga
    36781 gtgtggtaca cttttgttgt gtatataaat aaggaggagt tcagatgaaa aaaattcaat
    36841 taggtacttc tgatcagaaa gcagctgcag tgatcttagg ctgtatgcgt atcaacaatg
    36901 cggaagatcc agtaaaagtg attgagacag cttatgaaaa cggcattgat ttttttgacc
    36961 atgcagatat ttatggaaac ggtgaatgtg aagaaatctt tgcagatgct ctagcaaaaa
    37021 catcaatcaa acgagaagat ctttttattc aaacaaaatg tggaatcgtt ccaggtgtga
    37081 tgtttgattt ttctaaaaaa catatcattg aatctgtaga aaaaagtttg acccgtctga
    37141 aaatggatta tgtggatgct ttacttcttc atcgtccaga tacattggta gaaccagagg
    37201 aagtagctga agcgtttgat gaattggaac ggtcaggaaa agttcgttat tttggcgtca
    37261 gcaatcaaaa accaatgcaa atcgaattgc tgaaaaaata tgttcgtcaa ccattagtag
    37321 ctaatcagct gcaatttggc ttgaaacata ctggaatgat cgatcaaggg attcatgtca
    37381 atatgacaga tgaagcaagt atcgatcatg acggtagtgt acttgattat tcccgattgc
    37441 atgatatgac gatccaagca tggtcaccat accagtatgg attttttgaa ggtgtattta
    37501 tcgggaacga aaaattccct gaattaaacc aaacattaga agaactagca gctaaatatc
    37561 aaacgacacc aactggcttg gcttctgctt ggattttacg ccatccagcc aatatgcaag
    37621 tgatcgccgg tacgatgaac gtagggcgaa tcaaggaaat cgctcaagct tcagaaatta
    37681 atatgtctcg ggaagattgg tacgaattgt accgtgctgc tggaaacatt ttaccttaaa
    37741 gattgtcata agcaggtcaa aagggctata aattaaaaag acagaataac ttgaaagctg
    37801 ttttcagctt cgagatattc tgtctttttt tattgcaaat ggaaagagta tcattgtacg
    37861 gatttcgttt attagttatt tttgttttta aggaaaagct gtgtccgata ttcttttgga
    37921 gaaatccctt gttttttctt aaataaataa ctgaaatagt tagggtcatt ataaccaatt
    37981 tcaaaagcaa tatctgaaat acgatagtct gattgctgca ataatttttt tgctaattcg
    38041 attctttgtt ctgtcagata atcgatgaat gtttggttaa acgattgaga aaaaatcgta
    38101 ctgaaatgag agggacttaa tgcaacttgt tgagcgaccc aagttaagga catatctgga
    38161 tcggtaaaat tttctttgat aaaatccaat gcatggttca aaattggctg atatttgttc
    38221 cttgaaggct gtgagggcag agcagttaag aaagaaatga acatataaac tgtcgaacgg
    38281 taaagcgagt cgtcggcgct gattgctaag cgttgactgg tggatgtgca atgaaccatt
    38341 tcttgcggga ttttcttttc tttcaggcag acatgctgga gtagcttagt caagacaaat
    38401 aaacgatata atcgtgttcg agttggtgtg ccttgtggtt tcgtcaagtg ttcgatgtac
    38461 ttagatactt cgtttttcga taatgaagac aaatcaagtg agaggtcaaa gtaaaagaca
    38521 gaatcaactg gaagtttcgc ttcttgaatc aaatcctcat agctgataat ttgttcttta
    38581 agggaactgg cggtttcaag tatcatctgc gtgatctcaa aagatgcagg taattcgctg
    38641 attctttctg cgacaggacc aatggcgaca gaaaaattat ttttttgtcc cttttctaat
    38701 tcatggacca acgtttgggc tacctgataa ctggtctcga tcacattttc ttcaagagaa
    38761 tcaactatta aaaatttgat gaatcgagag gaaacagcag agaagatcac ttgttgattc
    38821 tccctaaata aaaacttcaa ataatcactg agatgagcgt aatcttcaaa gtctgtactg
    38881 acttggtttg ctgctaataa tacggtcatt tttttccctg ctaaagagcg attgaaagat
    38941 tcagcaagtt tcaatgtttc actgatcgta agtgagcctt tgaacaaacc gttcaagaaa
    39001 tgattttttt tcaattcgaa aacaagatca gaagaagtgt gcgtttcttt ttgctgcaaa
    39061 tctaaagcag ttactgcttt ttctattgct tgtttcaatt cgctactttt aatcggttta
    39121 agcagataat catctgcctg tacctggatt gctcctttca tataatcgaa atcgtcgaat
    39181 ccactaataa atatgagacg agtccaagga agtagtttcc ttgcttcttt tgaaaaagtc
    39241 aacccgtcca tgaaaggcat ttggatatca gtcagaatga tgtcgggctg taagtcgata
    39301 attgaagaca gtgccatctc accatctcca gcttcgccga cataagtgat tggataataa
    39361 gaaccaagga cagttatttg ttcccgcaag ttattgcgaa tgaggtattc gtcttcgatg
    39421 ataaaaactt tatacatgtt tgtttcctcc aattgttttg ggagatagag ggatcatcag
    39481 tgtgacagtt gttccttctc ggtatttgct gtcaatcgtg ataggttttt gatcatttcc
    39541 gtaataaaga aggagacgct tgtttacgtt gtaaagtccg tagccgatac tgaaatctga
    39601 atcgatccct ttggctaact ctttacgtat ttctgccagt ttttctgcag ggatgccaat
    39661 cccgttgtct ataactttga attggatcat ctcatcaatt ttgcatgtgg taatacgaat
    39721 aaatcctttg tgacggacgt acttcgttcc atggtataca gcattttcaa tcaatggctg
    39781 caagatcatt tttaaaatag aaacaggaaa aagtgtttct ggtatatcga tcttatagtc
    39841 aagcatatgg ccgtatctta tttttaagat gactagataa tcattgatat ggctaatttc
    39901 tttttcaaga ggaatccagt cttgtccttt gcttaaagac gtacgaaaaa agccggaaag
    39961 tgcatgggtc atagtcagag cttcttcaaa gcagtcttgt tcgatcaaag aaataatggc
    40021 atccaaactg ttataaataa aatggggagt aatctgagct tgcaatacac gaacttcact
    40081 ttgtgctaaa tggtattgtt tcaaagcgtt ctcccgtaaa gactggttta gatcttccgc
    40141 cattttattc atgctagcgg taagtgtttg taattccagt gtttccggca gggttaaacg
    40201 aaagccaagg ttccctgaag aaagttgttc tgacatctcg atcagctgat tgatcggttc
    40261 ttggaccttt ctctctaaaa agcgacgatt ctttttcgca tagaaaaaaa tggtactaag
    40321 aactccaagt tccactattg ttaatagaat gagcgagcgg acaagtgtcg tatttttttt
    40381 gcttgctaag tcgatctcca cacgaacaaa atcttgtaag atatctgaca gcagttgagt
    40441 gacagaatct acctgattga tgatctcttc attggtatcc ataaaatctt ttgccaagat
    40501 attattgatc agctcgtttt gataatcttc cagtgtatcg atcgtacgta gcgatacatc
    40561 taacgtacta atttctttaa gtgtatttgt attatttttg atctctcgaa tatcattcct
    40621 aagttcttct aggatatttt cctcattgaa ctcatctacg gttacttggc cagaaatcaa
    40681 gtcccacata ctttccaaaa ctttttgatc aaccttcaaa gcaattgcat ctgctttttg
    40741 gatatttgcg atcgtctgtt gataaatcaa aagctgttgc gaatataaca gtatgctcag
    40801 tagcaaaggg ataacagcaa atagaagcat ggctttgttt gcttgggcaa aaatctgttt
    40861 tatgcttaaa ttttttgtca tgatacttct ccagtcaata atttctggtt gggatgttag
    40921 ctatattctg ctgggaaaag acagtctcgg aaataaaaat atctttaggt aatgtttttc
    40981 ctgtttgaat atttccaaaa taacgagtaa cggtattggc tacataccag ccgacatcag
    41041 gtttacactc gactacacaa ttgacgattc ctgagcgtag cttctcgatc atatcttctt
    41101 gtccatcaat agttacaatg atcaaatctt ctccaggttt gattgatgtt tcttttatcg
    41161 cagctaaagc accgtgagtc atttcatcac tatggctgta taatacatcg atttcggata
    41221 aatcatttgt ttctaaatat cgtttcatct ggtcttttcc tttcatccga ataaaatcac
    41281 cgacaattcg gtgaacaata gtcatcggag gtttatggtc gatggttcca tcttttttta
    41341 gggttggttt acgattgatt gattccaaaa atccttcgga gcgtagcttg gtcggtgtgg
    41401 agttctctga accagcaagt tctaggattc tgatttcctg tttctttgaa tttgtgaagt
    41461 gattgctgac aaataaaccc gcccgatttc cttctgcttt gaaactgggg ccaatgtggg
    41521 tgacgaaaag ctcgggatca ttcgtttgaa tatgtctgtc gacaagtatg acagggatcc
    41581 ctgctcgctt tgcttctttt aatacagagt cccacccgga ttcttgcaaa ggagtaaaaa
    41641 tgatcatatc cactttatag gcaatgaacg tccgtatatc ttggatttgc cgttcctgat
    41701 tcatgtagcc atttcggtag agaacttggt aatcttcttt ttcaagcgca gtgataattg
    41761 attcagtatg ctttttccgc cagctactct ccgttcctga ttgcgaaaaa ccaacgacta
    41821 gtgggtcagg tgcttccttt gtattaggtg tacaccccat catttggtaa gcgattacaa
    41881 caagggctaa aaaaaataaa acacgtttca ctttaaatca ctccatctgg atttgttagt
    41941 actatcttat cagataaaag ggaaaatcaa agtcaaaagg aatcaatcga aaaaaatcca
    42001 agaaacttaa aaaaatccaa gacaaaaaaa gtacacctaa aaaatttaaa gtaaatccca
    42061 taaaaaaatc aatgttaacg ctttctttat tagctatact cggtgtatca attgaaatgg
    42121 gggataaaaa atgaaaaaca aatttagaaa gattgttggg actatcgcta ttttgaccgc
    42181 aagcattcta ttaagtgcgt gtggcaattc aggatctgca gatgatagta cggggtatgt
    42241 aggaatcgct atgccgacca aatcagcaga aagatggatc gctgatggga acaacatggt
    42301 ctcggaatta gaaaaactgg gttataaaac agatcttcaa tatggagaag ataaagtaga
    42361 aaatcaagta gcacaaatag aaaatatgat tacaaaaggg gtagatacac ttgtgattgc
    42421 ttctatcgat ggttcggctt taactgatgt gttagctaaa gcaaaagaag cagatatcaa
    42481 ggtgatcgcc tatgatcgtt tactgatgaa ttcagaaaat gtcgattatt acgcgacttt
    42541 tgataatttt ggagtaggtg tatcgcaagc agcttatatt gaagagcact taggattgaa
    42601 agaaggaaaa ggaccattca cgattgaatt atttggtggc tcgcctgacg acaacaacgc
    42661 actaatcaat tacaacggag tgatgtctgt tttacaacca tatatggaca acggtcagtt
    42721 ggtcgtgcca tctggacaga cgagtttcag tcaaatcgct acgcttcgct gggatggttc
    42781 tacggcgcaa gcaaggatgg ataatctgtt aagcgcaaat tatactgacc aaacattgga
    42841 tgctgttttg tcgccatatg atccaataag tttaggaatc atttcgtcat taaaaggcgt
    42901 ggggtatggg agtgaaagta aacctttacc tgtgattact ggacaagatg cgacagttgc
    42961 tggcgttaaa tcgatcattg ccggggaaca aacacaaacg atctttaaag acacacgtat
    43021 cttagcaaaa aatacgattg aaatgatcaa agcaatcagt gatggagaag aggttccggt
    43081 caatgatact gaaacttatg ataatggggt gaaaactgtc cctacgtatt tagcaaatac
    43141 agtatctgtc gataaagata attatcaagc agagctgatc gacaccgatt attataaaga
    43201 atccgatctg aaaaattaag aggaaccaaa caaggaacta aagagatcta agtcagagag
    43261 aggataagaa ttatggcgga ttgtatttta aaaatggcag atatcaccaa aaaattttct
    43321 ggaatccgag cgttagattg cgtgaatctg atgattgaac gtggggaaat ccatgcattg
    43381 tgcggagaaa acggagcggg aaaatcaaca ttgatgaatg tcttgagcgg cttgtatcca
    43441 tatggctcct atgacgggga aatcttttat gatggaaagc tgtgtcaatt taaagatttg
    43501 aaagatagtg aagaaaaagg catcgtcatc attcatcaag aattagcact aagtccttat
    43561 ctttcaataa aagagaatat ttttctcgga aatgaacaag cagaaagagg cgtgattgat
    43621 tgggaactga cagaaaagaa aacatatgaa ctgctgaata aagtcggttt gtctatcgac
    43681 ccgaatcttc tagtatccca gattggcgta gggcaacagc aactagttga aatagctaaa
    43741 gcattatcaa aatccgtccg tctgttgatt ttggatgagc ctaccgctgc attgaatgaa
    43801 gaagaaagcg cgaatttgct gagattgatc cgagagttga aagagcaagg tgtaacctcc
    43861 atcattattt cacataagct gaatgaaatc gtggatatcg cagatcgaat caccatttta
    43921 cgggatggac agacgattga gacactagaa aatgaaatga tcagcgaaga gcatattatt
    43981 cgcggaatgg tgggcagaga tttagttgat cgttatcctg aaagaaaacc ggatattgga
    44041 gaagtttatt ttaaagtaga agactggacg gtctatcacc ctcttgatca cgagcgaatc
    44101 ataaacgacc acatcaactt gcatttgaaa aaaggagaga ttgtaggaat agctggactg
    44161 atgggagcgg gcagaactga attcgctatg agtctatttg gacattctta tggaagcaag
    44221 atatccggac gtatattaaa ggaaggggca gagatatcag ttaagaccgt tccttcagcc
    44281 attgcaaacg gactcgctta tgtctcggag gaccgaaaat ctttaggact gaatctgctg
    44341 atggatattc gggaaaacgt gacgctgagc agtttggata aaataagtca aaaaggagta
    44401 ttagataaag aaaaagaagt aactgaggca gaaaatttcc ggaaaaagat gcgtataaaa
    44461 acaaactcca tccatcaaat tgtcagtagt cttagtggtg ggaatcaaca aaaagtcgtt
    44521 ttatccaagt ggctgatgac acaacccgat attctttttt tggatgagcc aacccgtggg
    44581 atagatgttg gggcaaaata tgagatctac acgattatcg aagaaatggc agcaaatggc
    44641 aaagctgtct gtcttatctc ttctgaactt cctgaaatat tagggatgtg tgatcgaatc
    44701 tatacgatga acgaaggacg tattacagga gaagtctcgc gagaagatgc agatcaggaa
    44761 gtcttgatga aattaatgac gaaagaagag gtgggttaag ttggaacagg caaaaaatct
    44821 tacggataaa aaagagaaaa aactaaattt gaaaagtaga gcagctgatc tttttggtcg
    44881 ctacagcatg gtgatcattt tagcgggact acttattgcg tttcaattga tgacggatgg
    44941 tattttctgg cgtccattga atataactaa ccttgttctg caaaatagcc atatattagt
    45001 actagctgca gggatgttat tagttgtgct cttaggtcat gtggatttgt cggtagggtc
    45061 agtgatggcg tttgttggtg caattgcggg catgatgatg gtcaatcgcc aaatgaaccc
    45121 gtggatgaca gttatcgcat gtcttgcagt aggcgggctg atcggcgcat ggcaaggttt
    45181 ttgggtagct tatgcaggga taccggcgtt tatcgtgact ttagcaggat tgctgatgtt
    45241 tcgtggactg acacaagttg ttctaggagg ccaatctcta gcaccttttc cagctgtttt
    45301 ccaaaaaatg tctacgggtt atttaccaga cttaagcgaa ggaagcagcc ttcacttctt
    45361 gacattgatt ttaggaatga tcatcacgat cgtgttagtt gttggtcaat ggcgaacaag
    45421 aaatcgtcgg aaaaatcatt tatttgaagt ggaatctcca acagctttct tggtaaaggc
    45481 ggtatttaca gcagtcgttg tactaggaat aacttatatc tttgcctctt atcaagggta
    45541 tccgattatt ttgatcattc ttggtttgat cgttgcagca tatgggtttt tgacaaataa
    45601 aacagtagca ggtcgacaga tttatgcgac gggcggaaat cgaaaagcgg ctgaactatc
    45661 agggatcaaa acaaagcgaa tcacgttctg ggtattcgtc aacatgggag tcatggcagc
    45721 tttagctgga ttagttttag ctgctcgatt gaatgcggca acacctcaag caggtacatc
    45781 gatggaactg gatgcaatgg cggcagtata ttttggtggt gcttcgactt ccggcggcat
    45841 tggaacaatc atgggtgcga ttgtcggtgg cttggtcatg ggtgtattga acaatggcat
    45901 gtcgatttta ggcgtcgggg tagactggca gcaggcaatc aaaggattga tcttgctttt
    45961 agccgttgtg ctagacttgt ataataagaa aaaacgaaca acgtaggaga acgccggtta
    46021 ttcagaaaaa agactgtgac aagacatttg tcacagtctt tttttcgcta aaagcgaaca
    46081 ttcattgttt cgtttgtata gactaaaaat aatatatgtt tttttaccat tcgtataaat
    46141 tctctttttg ctcttgattt ttttgcttaa ttgagttaaa ttacataggg cgctaaaaaa
    46201 agccttgatt aaattaataa tgttcgtgtt ttgctggatg tgaacatcag gaggataatg
    46261 taatgaaagt atttgattac gaagatattc aattaattcc taataaatgt atcgtaaata
    46321 gccgttctga atgtgataca acggtcacat taggtaaaca tacattcaaa atgccagtag
    46381 tgcctgccaa catgcagacg attattgatg aaacaatcgc agaattctta gcggaaaatg
    46441 gttatttcta tatcatgcat cggtttgatg aagcagctcg aattccgttt atcaaaaaaa
    46501 tgaaaaagcg tggattgatt acctcgatca gtgttggcgt caagaaagag gaatattcct
    46561 ttatagagaa gttggcagaa gaatcgctaa atcctgatta tatcactatc gacatcgcgc
    46621 atggacatgc taactcagtt attgatatga ttcagcatat taaaaaatat ttgcctgaaa
    46681 cttttgtgat tgccggtaat gttggtacac cggaagccgt ccgtgaattg gaaaatgcgg
    46741 gcgcagatgc aacaaaagtc gggattggtc caggaaaagt atgtattaca aaaatcaaga
    46801 caggctttgg gactggaggc tggcaactgg cagctcttag atggtgtgcg aaagcagctc
    46861 gcaagccgat catcgctgac ggtgggatca gaacacatgg cgatattgca aaatctgtcc
    46921 gttttggtgc gacaatggtc atgattggtt cattgtttgc cggtcacgag gaatctcctg
    46981 gcgaaacaaa agtcgaaaat ggaatcgtgt ataaagaata ctttggttct gcttcagaat
    47041 tccaaaaagg cgaaaaacga aatgttgaag gaaagaaaat ctggatccaa cacaaaggat
    47101 ctttgaaaga tacactagtg gaaatgcaac aagaccttca atcatctatt tcttatgctg
    47161 gaggaagaga tctggaagcc attcgaaaag ttgactatgt catcgtgaaa aattcgattt
    47221 ttaatggaga cacaatctaa aaaataaata aaatattagg atgttgtgaa aaagttgtcc
    47281 tgcattaagt aataagaaca gccaaacaaa aatagttctt tatatgtttt gtttggctgg
    47341 aattattatc gcagatacaa gcttttgaac atcattattc agaataaggg actgtgataa
    47401 gatttttgtc acagtccctt atgttttgca aaaaaagttt ttcttttttc tcgtaaattc
    47461 ggtaaaatca aaagaaaaaa tagacaatag aaaagagaag cttatgtggg aaaaagtaga
    47521 gaaaaaacaa ggaccgattt atcgtcaaat tatggaacag attatgagag aaatcgaaaa
    47581 cggaaggatc aatcctggaa gtcaacttga atcagaacga aaactagggc aactttttgg
    47641 tgtgaatcgt tccaccgttg tccatgcatt ggaagagctt agggagcttg gggtactaac
    47701 gagcaaacgt ggcagcggat ggtttgttaa tcagactgaa tgggggaaat tcgctgttcc
    47761 aagaatcgat tggcggcaaa tgatctctcc tcgttatgag cagacggact ggtatgagca
    47821 aaaaataaga gaagcaaagc agatccaaaa aacatcgttt cttgatttat acgctagcga
    47881 gatgccagat gagcttttgc cgaattttga gtttccttct tattctcttg aagaaatctt
    47941 agcggaagaa aaagaaatgg atcttttagg ctatactccg ttacgtaaca aaatcaaacg
    48001 gtatttggaa agtaaatttg aattggcatt ttcccccaac cagcttcttg tgactggtgg
    48061 cggtcagcaa gcaatctttt tgattttaca aacgattctt tcagctggag aggggatagc
    48121 tgtagagtca ccttcttttt tttaccgatt acctcttttc aaagcttcag gaacgcgttt
    48181 atttgggata ccgatggatg aagaagggat cgacttagaa aaactgaaag aatcgatcca
    48241 taaaaataaa ttgaaagcag tgcttatcaa cccgaatttt caaaacccta caggaaaagt
    48301 gatgagtcaa aaacgacgag aaaagctagt agaattgtgt cgacagtatc ggcttccaat
    48361 tattgaagac gatgtattta cggatctttc atttctaaac caagaagaag tccttcctat
    48421 acgaacgatt gatccggata atgtgttata cgtcggttcg ttatctaggg ttttaggaaa
    48481 aacaacgaaa atcggttggg tgataggacc tgagactttt atctcgcaac tagctcaagc
    48541 gcaagaaatg atggagtttt cgatgaatat ccttacacaa atcacagtgg ctaatgtatt
    48601 taatgaagca attgatttga aaatgcaaga tgtaagaaaa aagttgaaag aaaaaagccg
    48661 actgataagc gcttggggag attcacaatc gtttttcaag cttcattcaa ttttaggtgg
    48721 ttactatgcc tggattactt gggatgggaa aaaactagac cccgaactag cagaaaaagt
    48781 agtagatatg ggtcttggaa ttgcaccaag tctacttttt gggcaagata taaatggaat
    48841 cagaatcaat tacagtaggc tggatgaaaa ccaaataccg ttgttttatt caaagatgaa
    48901 aattctagaa aagtggttaa cagaataatt tcacaaagta aatagattaa agaatataac
    48961 agcttggatt taaatttcaa gctgtttctt ttttttcgga aaaagaatac gatataaaga
    49021 aactaagaaa aaaccattat ttgtacgtcc gttcacgatg tgtaaataaa ataaatgttt
    49081 gcaacaaaac tgtataacac caacgttttt aaatagaaac agatggttgt aagtttgatt
    49141 agaaaataga aaaaatgcag atgaaatata aaacgctttc cttattgtga ttttattcac
    49201 taatgctgtt aatatgcgga ttggcataat ttcctttcat cgtgaaaatt tgtgctttta
    49261 gcttgtattt ctcataaatc catgataatt tattaatgaa gacggttaaa tagtgataca
    49321 gttttattca ctgtttcaat cgcagaatga agagattttc ttatagatga gagaggaatg
    49381 tgtgacaaat ggcaaacaaa aaagcaccga tcgacttcca agcactgcta gatgaagtca
    49441 atgcagattt cccagtatat caagcacttg atcaagatgg aaacgtagtt aacaaagatt
    49501 tagtacctga tttatccgat gatgaactcg ttgaattaat gactcatatg gtatggtctc
    49561 gtgtattaga ccaacgttca acagcgctga accgccaagg acgcctaggc ttttttgcac
    49621 caactgctgg acaagaggca agtcagctgg ctagtgctta cgcatttgat aaagaagatg
    49681 ttcttcttcc aggttatcgg gatgtacctc aactagtaaa acatggttta cctttatctc
    49741 aagctttttt atggtctcga ggacatgctg caggtaattc ttatccggaa gaattgaaag
    49801 ctctaccacc acaaattatc atcggtgcac aatatgtaca agcagccggt gttgcattag
    49861 gtttgaagaa acgaaacaag aaaaatgtcg tcttcactta tactggtgat ggcggttcat
    49921 cacaaggtga tttttacgaa gcaatcaatt tcgctggcgc ttaccatgca aatgccgtat
    49981 tttatatcca aaacaacggg tatgcgatct ctacacctcg tgaaaaacaa actgcagcaa
    50041 aaacacttgc acaaaaagct gtcgcagctg ggattcctgg tattcaagtc gatggaatgg
    50101 atccgcttgc agtatatact gtatctaaaa tggcacggga atgggcgatc agtggaaatg
    50161 gaccagtcct aatcgaaaca ctgacttatc gttatggacc acatacacta tctggtgacg
    50221 atccaacccg ctaccgtaca aaagacacag atgacgattg gcagaaaaaa gatccattga
    50281 tccgcttccg taaatatttg acggaaaaag gactttggtc tgaagaaaaa gaagaacaag
    50341 tcatcgaagc aactaaagaa gaaatcaaag cagctattgc tgaagccgac aaagtaccaa
    50401 aacaaaaggt ttcagatttc ttgaaaaaca tgttcgaagt atctccacaa tcaatcaaag
    50461 aacaaattgc aatttatgaa gcgaaggagt cgaaataatc atggcacaaa aaacaatgat
    50521 ccaagcaatc acagatgcct tagcacttga actagaaaat gacgagaatg tcgttgtttt
    50581 tggtgaagat gttgggaaaa acggaggagt tttccgggca actgaaggat tgcaggaaaa
    50641 gttcggagaa gaccgagtat tcgatactcc tttagctgaa tctggaatcg caggattgag
    50701 tttcggtctt gcgttagaag gatttcgtcc agttcctgaa atccaattct ttggttttat
    50761 tttcgaagca atggacgaag tagtagctca aatggctcgt acaagatatc gaatgagcgg
    50821 cactagaaat ctacccatca caattcgttc gccatttggt ggcggtgttc atacaccaga
    50881 attgcattcg gataatttag aaggtttgat cgctcagtct cctggtattc gagtagtgat
    50941 tccttccaac ccttatgatg caaaaggact attgatttct tctattagaa gtaacgatcc
    51001 ggttgttttc ctagaacaca tgaaactata tcgctcattc cgagaagaag tgccggatga
    51061 agcttacgaa gttcctttgg ataaagcagc agttactcgt gagggaacag atgtatctat
    51121 tatcacatac ggagcaatgg tgcgtgaagc aatcaaagca gcagacaatc ttgcaaaaga
    51181 aaatatatct gttgaaatca ttgatcttcg tacagttgcg ccattagatg tagaaacgat
    51241 cattcaatcc gtggaaaaaa ctggtcgcgt agttgttgtc caagaagcac aacgacaagc
    51301 gggcgttgcc gcgcaagtag tttctgagat ctcagaacgc gctatccttt cattagaagc
    51361 cccaatcgga cgagtttctg cacctgatac agtcttccca tttggacaag cagaaaatgt
    51421 ctggttgcca aatgcaaaag atatcgaaga caaagtaaaa gaaatcgcgg aattttaaga
    51481 aaagaaggga cgaaacaaag tcatggctta tcaatttaaa ttgccggata tcggtgaagg
    51541 aatcgcagaa ggtgaaatcg tcaaatggtt cgtcaaacca ggagatacga tcaatgaaga
    51601 tgatacatta ctagaagttc aaaatgacaa atcagtagaa gaaatcccgt cacctgttac
    51661 aggaacggtt aaaaatgtga ttgttccaga aggtaccgta gcaaatgttg gggatgtatt
    51721 agtagaaatc gatgcaccag gacacgaaga caatgaaggg gacagtggtg tagccgcaga
    51781 atcccaaact ccagctaaac cggctgctga acccactgtt gatacagaat cagctggatc
    51841 gtcaagcgaa ggagtcttcc aatttaagtt accggatatc ggtgaaggaa tcgcagaagg
    51901 tgaaatcgtc aaatggttcg tcaaaccagg agatacgatc aatgaagatg atacattact
    51961 agaagttcaa aatgacaaat cagtagaaga aattccgtca cctgtcacag ggacagttaa
    52021 aaacgtgatt gttccagaag gcactgtagc aaatgttggg gatgtattag tagaaatcga
    52081 tgctcctgga cacaatagtg caccgtcaac tagtgcgcca tcagctgaag caccaaaaga
    52141 aaaagtggaa acatcaggtt cagcaagtgt cgttgaagct gccgatccaa ataaacgtgt
    52201 attggctatg ccatctgttc gtcaatttgc ccgtgaaaaa gatgtagata tctcacaagt
    52261 aactgcaact ggaaaaggtg gcagagtaac aaaagaggac atcgaaaact tcttggcagg
    52321 tggtccaagc agtgcaccag cgaaatcaga agcgccagaa gcggcagcac cgaaagaagc
    52381 agctcctgca gcagaaagca aaccagctgc accagcaaaa ccattcaagt ccaacttagg
    52441 agacttggaa gaacgtgtag caatgacgcc aacacgtaaa gctatcgcta aagcaatggt
    52501 caacagtaag catacagctc cacacgtgac attgcatgat gaagtagaag tgtctaaact
    52561 atgggataat cggaaacgat ttaaagaagt tgctgctgca aatggtacga aacttacttt
    52621 cttgccatat gtcgtgaaag ctttaacagc gactgttaag aaatacccag tattgaatgc
    52681 atctatcgac gatgcaaacc aagaaatcgt ttataaacat tactacaata tcggtattgc
    52741 aactgatacg gatcacggac tatatgtacc aaatgtgaaa gatgcagacc gcaaaggaat
    52801 gtttgctatt gcagacgaaa tcaatgagaa agcaaaatta gctcatgacg gcaaactatc
    52861 tgcagaagat atgcgcaatg gaacaattac gatcagcaat atcggatctg taggtggcgg
    52921 ttggtttaca ccagtcatca actatccaga agtagctatt ttaggtgtag gaacgattgc
    52981 acaacaacca atcgtaaatg ctgaaggcga aatcgttgtc ggtcgtgtga tgaaactgtc
    53041 attaagtttc gatcaccgta tcgtagatgg agcaactgcg caacaagcaa tgaataatat
    53101 caaacgtctt ttagctgatc cagagctatt aatgatggaa ggatgataaa caaatggtag
    53161 ttggagattt tgctgtagaa ttagatacag ttgtaattgg tgcgggacct ggtggctatg
    53221 tagctgccat ccgcgctgct gaaatgggac aaaaagtagc aatcattgaa agagagtata
    53281 ttggcggtgt ttgtttgaat gtcggctgta ttccttcaaa agcactgata gctgcaggac
    53341 accattatca agagtcacta gattctgaaa tgtttggagt aactagtgaa aacgtcaaac
    53401 tagattttgc aaaaacacaa gaatggaaag aaaacaaagt tgtccatacg ttgacttctg
    53461 gtgttggttt cctattaaaa aaacataagg ttgaaacaat cgaaggagaa gcgttcttcg
    53521 tagatgatca cacactacgc gtcattcatc cagattcagc tcaaacttat tcgttcaata
    53581 acgcaatcat cgcaacaggt tcccgtccaa tcgagattcc aggatttaaa ttcggaggac
    53641 gtgtgttaga ttctactggc ggattagcat tgaaagaagt acctaagaaa tttgtgatca
    53701 tcggtggcgg tgtgattggt gccgaattgg gcggagcgta cgcaaactta ggagcagaag
    53761 taacgattct tgaaggctca ccacaaattt taccaactta cgaaaaagat ctagtaaaat
    53821 tagtagaaga tgatttcaag aaaaaaggcg taacagtcgt aacgaatgca atggcgaaag
    53881 aagcagtcga taacggtgac agcgtgacag tgaaatatgc agtggacggg aaagaagaat
    53941 ccgttactgc tgattatgtg atggtcactg taggtcgtcg tccgaataca gatgatatgg
    54001 gcttagaaca agcgggtgtc gaagtaggag aacgaggatt gatcacggtg gataaacaag
    54061 gacgtacgaa cgtacctaac atctatgcca tcggtgatat cgttccaggg gcggcattag
    54121 cacacaaagc cagttatgaa gcaaaaatcg ctgctgaagc aatctctggc aaaaaagtag
    54181 ctgtagatta taaagcaatg ccggcagtag ccttcactga tcctgaattg gcttctgtag
    54241 gtatgacgat caaagaagca aaagatgctg gtatcgaagc aaaagcatat aaattcccat
    54301 tttcagggaa cggtcgggca ttatcgcttg gtaaaacaga aggattcatc cgtctagtta
    54361 cgacgatcga agataacgtg cttattggcg cgcaaatcgg tggagtcggc gcaagtgata
    54421 tggtctctga attagcttta gcaatcgaat caggaatgaa tgctgaagat atcgccttga
    54481 cgattcatcc tcatccatct cttggcgaaa tcgtcatgga tgcttcggaa ttagcattag
    54541 gtttaccaat ccatatttga tttgaataat acaggcgaaa cgcaactgaa aaatcagttg
    54601 cgttttgttt tttagaatta tcaataatat tattatgtaa acttaaaaat atgacaactt
    54661 cttggtttat taccacttcc tatgctacac tgaagaggaa tatgaaatag gagagttgaa
    54721 gatgcaagaa tatcagtatc cacttgattt agattggaca acagacgaaa tggtcattgt
    54781 aatgaagatg tgggaagatc tggaacgtgc gaatgaaaaa gggataaaca atgaagcttt
    54841 tttgaagact tatcagcagt ttaaaactgt tgtcaaatcc attggtgagg aaaaacgatt
    54901 gggacgggaa tttgaaaaag cttccggtta ttctttatat cgtacagtgc agcaagcaaa
    54961 aaaaaatcca aacaaaactt tgagaatgaa cgggtgagat aaatggaaca gatgattgat
    55021 catatcaagt cctggcttga agaagctggt gagaaaatca aatcttctca acaaacatta
    55081 acaatctcgc aaaaatcaaa tcgaacggat ctagtaacaa atgtcgatcg aaacatccag
    55141 aattttctaa tcgaaaaaat ccattccttt gatccagagg cgaaaatatt ggcagaagaa
    55201 gaagggtgta atcaattatc ggatctcgat ggaagagtct ttatcatcga tcctattgat
    55261 ggcaccttga attttgtgat tgaaggggaa aatttttgta ttatgctcgc tgtttatgaa
    55321 tccggcgttg gaaagcttgg tttcatttat gacgtgatga gaaatgaact tttttggggt
    55381 ggaaaaggaa taggcgtgta taaaaatgat gagccattgc ctagaccagc aaataaatcc
    55441 ttatcggaag gcttacttgg tgtgaatagt tatcttttcg gtcataataa atatggaatc
    55501 cgagaaattg cggaaagcag catggggaca cgtatgtacg gatgcgctgg tcttgaacta
    55561 gtggcaatct tgaaaggaaa ccacattgct tatatttcaa accttagccc ttgggattat
    55621 gcagcgggaa atgtcttatt ggaagagttt ggtatggtaa caagcggtct ttttggtact
    55681 cctttgacat ttgaaaaaag ggaatactat ttagcaggga cttcttgtgc atatgcagaa
    55741 atcgcagacc ttttgaaaaa agaaggctga aaaaaaggta gaaatcattc acaaaaatga
    55801 taaaaacgag caaaagatta attttctcga aaaaatgaaa acattttact atatttcatg
    55861 aaaaaagtct gctataatta gcagtcgagt aaaatttgcc ctgtcataaa gaaccaataa
    55921 aaaaggagtt agttacattg aattatagaa acgatatccg taacgtcgca attattgccc
    55981 acgttgacca cggaaaaaca acattagttg atgaactatt aaaacaatca gatacattag
    56041 acgcacatac gcaattgcaa gaacgtgcga tggactcaaa tgcgctagaa aaagaacgtg
    56101 gtatcacgat tttagccaaa aacacagctg tagactataa aggtattcgc gtaaacatca
    56161 tggatactcc aggacacgcg gacttcggtg gcgaagtaga acggatcatg aaaatggttg
    56221 acggcgttgt gttggtcgta gatgcgtatg aaggaacaat gcctcaaaca cgttttgtat
    56281 tgaaaaaagc actggaacaa catatcacac caatcgttgt cgtaaacaag attgacaaac
    56341 cttctgctcg tcctgagcat gtcgtagatg aagttcttga actattcatc gaattaggag
    56401 cagatgatga tcagttagac tttcctgtga tttatgcatc tgcactaaat ggtacgtcaa
    56461 gcttgtcaga tgatccagca gatcaagaac caaccatggc acctattttt gatacaatta
    56521 ttgaaaaaat ccctgctcct gtcgataaca gcgacgaacc attacaattc caagtttcat
    56581 tacttgacta caacgattat gtaggtcgta tcggaatcgg acgtgtattt agaggaacaa
    56641 tcaaagtagg agaccaagta gcattaatta aattagacgg aacagttaag aaattccgtg
    56701 taacgaaatt atttggtttc tttggactaa aacgtctaga gattcaagaa gcaaaagctg
    56761 gagacttgat tgctgtctca ggtatggaag atatctttgt cggtgaaaca gttactcctg
    56821 tggatcatca agatgcgtta cctatccttc acattgacga accaacattg caaatgactt
    56881 tcttagttaa taattcacca tttgccggtc gagaaggtaa attcgtaacc gctcgtaaga
    56941 ttgaagaacg tttgatggca gaacttcaaa cagatgtatc cttacgagtt gaaccaacaa
    57001 actctccaga tgcatggaca gtttctggtc gtggagaatt gcatttgtct atcttgattg
    57061 aaaacatgcg ccgtgaggga tacgaattgc aagtatctcg tccagaagtt attgaaaaag
    57121 aaatcgacgg tgtaaaatgc gaaccgtttg aacgcgtgca aatcgataca ccagaagaat
    57181 atatgggtag tgttatcgag tccttgagct tacgtaaagg tgaaatgcaa gatatggtcc
    57241 atacaggaaa cggacaaatc cgtttgacat tcttaacacc tgcccgcggt ttgattggtt
    57301 attcaactga attcctttca atgacacgtg gttacggaat catgaaccat acttttgacc
    57361 aatatctgcc aatgcttcct ggtcaaattg gcggacgtca ccaaggggcg cttgtttcga
    57421 tcgatacagg aaaagcaacg acttattcta tcatgagtat cgaagaacgc ggtacagtct
    57481 tcgtagaacc aggtacagaa gtatatgaag gaatgattat cggggaaaac agccgtgata
    57541 atgatttgac tgtcaacatc acgaaagcaa aacaaatgac aaacgtacgg tctgctacta
    57601 aagaccaaac atctgtcatc aaaaaaccaa aacaattgac gttggaagaa tctttggaat
    57661 tcttgaatga tgatgaatat tgcgaagtaa caccagaaag cattcgcttg agaaaacaaa
    57721 ttttagagaa aaatgctcgt gaaaaagcat ctaaaaagaa aaaataatct gtaaaaggat
    57781 gaagagagaa accagcttgt tataaaaaat agctggtttc tttttttgtc caactctttt
    57841 ctgtggagaa gtcatctttg tcaatggaca taaattcaga aaatacgccg aaagacgttt
    57901 aaaagacttt taaaaaactt atttctagag agtttttgtt tcataataag ataatgtttc
    57961 acgaaaggag atcaacttgt ccttcgaaga aaatcgaagt aaaatggcaa gagaaaggag
    58021 cgggaagatg aacgacttat taaaacaata ctttggctat gatgagttta gacctggtca
    58081 aaaagaaatt atccagaaag tcattgatca ggaaaatgta ttaggaatca tgcctaccgg
    58141 aagtgggaaa tcaatctgtt accagcttcc agctttacta ttagatgggc ttactgtggt
    58201 tgtgtcccct ttaatctctt tgatgaagga tcaggtggac gcggcgaatc aattaggtat
    58261 acccgccact tttatcaata gctcgttaga tggttacgaa acagctagac gcttccaaga
    58321 aatcgataga cagcagtacc gtttacttta tatcgctcct gaacgtttta tcatgccgga
    58381 ttttatccaa gcaatgaagc gatggaacgt ccgtatgatc gctattgacg aggcacattg
    58441 tatctctcag tgggggcatg atttccgccc aagttattta cagatggcga accagctaga
    58501 tcaactgcca aatcgtcctg taattgttgc tttgacagct acagcgactg tgcaagtagc
    58561 tgctgacata aaaagacttt taaaaattcc agaaaacaac catattcaga ctggttttga
    58621 acgagaaaat ctacgatttc aagtaattaa agatcaaaaa aaagaacaat atctaatcga
    58681 atatttaaag atcaacaaaa atcaatctgg tatcatttat gcagcaacga gaaaagaagt
    58741 agaccgtctc tatcatttgc ttaaaaaatt cgatttttcc gtgggtagat atcatggtgg
    58801 tctaaatgag aatgagcgaa cagaaatgca agaagccttt ttatacgatc gcttgcagct
    58861 gattgtagcg acaaatgcat ttggtatggg tataaataaa agcaatgtcc gttttgttat
    58921 ccattatcaa attcctggct ctctagaagc atactatcag gaagctggtc gggcgggaag
    58981 agatggtctt tccagtgaag ccatcctgct tttctctcct caagatatcc aagtccaaaa
    59041 gttttttatc cagcagtccc aaagagaaga agggcaaaag caaaaagaat atgaaaaatt
    59101 aaaagcgatg acagaatacg tgtatattga gtcctgtctt cagcaataca tcctaaacta
    59161 ttttggcgag acaagcagtc cgtgcaaccg ttgtggtaac tgtttagatg acagagaaat
    59221 agtagaagta acgacagaag cacagatggt tctttcttgc ttaaaacgta tgggtgagaa
    59281 ctatggtaaa caaatgctga tgaaagtctt agcaggatcg aaagaacaaa agctgcaagc
    59341 tttaggtttt ggacatttat ctacctatgg actgatgaaa aaccaatcgc aaaaagaaac
    59401 gatgcagtta attgaatatt tgatatcgaa tggctatctt ctgaccatca atggtgagta
    59461 tcctgttttg aaagtaacag aaagagggat acaagtattg aaaggacaag aatctgttta
    59521 tcgaaaggaa cccaagaaag tccagcagct atcggatgaa gaaaccgata cactatttga
    59581 agtgctgcgg gaactgcgaa cggatctagc atcagaagca ggcgttcccc cgtatgtcgt
    59641 attttcagat tccacattga aagaaatgag ccgaatacgt ccatcaagca gattggagat
    59701 gcttcagata aaaggagttg gccaaagcaa gcttgataaa tatggcgaag cctttttatc
    59761 tcggataaaa aatgcggact ctaacgttct ggataagtag aaagaacgaa tacgtaaaaa
    59821 tgaataaaaa caactggtta aatctgtttt ttttgctcct tatgaaaatc aaatatgtta
    59881 taattaagga attagaatgg gaggtaagca cagatggatt ctttgtcgaa aaaacttgcg
    59941 atccaagtat taaatgatga agcagaacgg atcaaacgat taatccgaaa tcaaaacaac
    60001 agtctctgta tctcacaatg caaagccttc gaagaagtgg tagatacaca gatgtacggc
    60061 ttttcccggc aagtcggttt tgctgtccgt ataggagtaa tcggaaagaa cgagggccag
    60121 ctgatgttaa gtgagctaga acgagaattg aatcagttat atagtgaggt ttaccaagaa
    60181 atttatgata aaaaagaagt tggcaaggag gaatagactt gcctaagaaa gtgaaaaaaa
    60241 ggcatctatt agactatagc atcttgattc cctatttaat tttatgtgta ttgggattga
    60301 tcatggtata tagttctacg tcgtatctat tattagaaaa cggacaaaat ccgtccgcat
    60361 cagtcattaa ccagagtatt ttttgggtgc ttagcttgat tgctatcgca ctactttata
    60421 aaatgaaaac agatgttttg aaaaaccagc gtttgatcat ggcagccatc gcagttttga
    60481 cgattttgct gctgattgtt gtgttttttg gtaaggagat caatggggcg aaaggttggc
    60541 tgcaaattgc aggattctcg atccaacctg ccgaatacct aaaaatcatt tctatctggt
    60601 acctgtctct gactttatct aaaagacaaa acagtgtaca aaaagatttt cttgggactg
    60661 tgaaacgtcc acttgcaatg gttatcggac ttactgcatt agtcgctatt cttcccgatt
    60721 ttggtaatgc ggcagttatc tttttgatta ttttggttct gcttttagcc agcggagtca
    60781 attatgtgta tactttgatt gtaggagtag gaggcttttg tctaagtact tttacgatct
    60841 ggctgatcaa tatcacaaac ggaaagatct tacccggacg tttacagtat atctataatc
    60901 gatttgctat ttaccaaaat cctttctcag acgaattaaa taaagggcat caactagtca
    60961 acggctacta tgccatgttc aacggaggac tatttggcag gggattaggt aacagtatcc
    61021 agaaaaaagg atttttacaa gaagcacaaa ccgattttat ttatgcaatc gtagtggaag
    61081 aactgggagt gattatgggg attttgatat tagcgttgct attctttatg attgtgcgca
    61141 ttgtccttgt aggtatccgt tcaaaagatc cgttcaattc gcttttgtgc attgggatcg
    61201 gcgcaatgtt tttgatccaa gtatttgtca atcttggagg aattactggc gttattcctt
    61261 tgacagggat cacgttccca tttttaagtc aaggaggctc cagtttgctg atgctttcga
    61321 tttgtgtcgg ctttgtcctc aacatcagtg cggatgaaaa acgcaagagc ttaggtttat
    61381 aataaaaaaa gatgtaggag tggttcgatg aaaaaagttt tagttgctaa caggggtgaa
    61441 atcgctgtac gtgtatttcg tgcttgtaca gaattaggaa ttaaaactgt tggaatctat
    61501 gcagaagaag atgaatattc cgtacaccgt ttcaaagcgg atgaagcata tttagtagga
    61561 caaggaaaaa aaccgattga tgcgtatcta gatattgaag ggatcatttc tatcgcgaaa
    61621 gaatgcggag ctgacgctat tcatccgggt tacggtcttt tgtcggaaaa cttgaatttt
    61681 gcgcaacggt gcgaagaaga aggcatcatt tttgttggac ccaaactgca tcatttagat
    61741 atttttggag ataaaatcaa agcaaaagct gcagctatcg aagcggggat tgcttcgatt
    61801 ccaggcacag atggaccaat cgcttctata gacgatgcct tggagtttgc gaaacaatac
    61861 ggttatccga ttatgatcaa ggcagctcta ggcggcggcg gacgcggcat gcgtgtagct
    61921 cacgatgaaa agagtgcaag agagggctac gaacgtgcga aaagcgaagc aaaagcagcc
    61981 tttggtagtg atgaagtgta tgttgaaaaa tacatcgcta atcctaagca tatcgaagta
    62041 cagattctcg gggatacgca tggaaacgtc atccatcttt ttgaaagaga ttgttctgtt
    62101 cagcgccgtc accaaaaagt agtagaagta gcgccttgtg tctctatgaa tgaacagcaa
    62161 cgtcaaaaaa tctgccaggc agctgtccaa ttgatgaaat atgtcgggta tgtcaacgca
    62221 ggtacagtag aatttcttgt tgaaggagat gatttttact ttatcgaagt caaccctcgc
    62281 gtccaagtgg aacatacgat cacagaaatg attacagata ttgatatcgt aacaacgcaa
    62341 ctgttgattg ctcaaggttt ggatctgcat aaagaaatcg gattgcctca gcaagaagga
    62401 attaaattaa atggttcagc cattcaatgc cgaatcacta cagaagaccc gttgaataac
    62461 tttttaccag acacagggaa aatcgatacg tatcgttcac ctggtggttt tggcgtacgt
    62521 ctggatgtcg gaaatgctta cgcgggctat gtagtgacac cgtattttga ttcattgcta
    62581 gtaaaagtat gtacgcatgg tgctaccttt gaaacagcca ttcagaaaat ggaacgttgc
    62641 ttgaaagaat ttagaatccg tggagtgaaa acaaacattc catttatgct caatgtcatc
    62701 acacatcctg aattccaatc aggaaatgca aaaacaacct tcattgatag tacagcaaca
    62761 ttatttgaat ttcctcgact acgagaccgc ggaaacaaaa cgatgaaata tatcggtgaa
    62821 attactgtga atggttttcc aggtatcgaa agtggcgaaa aaccatttta tgaagaacca
    62881 cgtatgccta aagatctaat cacaagaact gattacgtaa cggctaagaa tgtattagat
    62941 gcgaagggtg ccgatgcttt ggtcgaatgg atcaaaggac aggaaaattt gttgttgacg
    63001 gatacgacat ttagagacgc ccatcaaagt ctgctagcaa ctcgtgttcg gacaaaggat
    63061 ttcaagcaga ttgcacgttt gactggagaa ggtcttcctg aactcttttc aagtgagatg
    63121 tgggggggag caacatttga tgtggcttac cgctttttga atgaagatcc ttggcaacgg
    63181 ttgagaaaaa ttcgttcttt aatgcctaat acgttgctgc aaatgctttt cagaggttca
    63241 aatgccgttg ggtattctaa ttatcctgac aatgtattgg tggaatttgt caaagaagca
    63301 gcagcgcaag gaatcgatgt atttcgaatc tttgatagtt tgaactggac tccacaaatg
    63361 gaaaaaagta tccaagctgt acgggatact ggtaaaatcg cagaggcagc tatttgctat
    63421 actggcgata tcaacgatcc aagtcgggca aaatacaatg ttcagtatta taaagacatg
    63481 gcaaaggaac tagaacaact gggtgcgcat atcattgcaa tcaaagatat ggctgggctg
    63541 cttaaaccgc aggcagctta tcgtttgatt agtgaattga aagaaacgac agatctgcca
    63601 atccatctgc atactcatga taccagcggg aatggaatca tcacttattc tgctgcttca
    63661 aaagcaggag tagacatcgt tgacgtggca atgagtgcaa tgagtgggaa tactagtcag
    63721 cctagcatga gcagcttgta ttatgcactg gtcaatggtc cacggctgcc agaaatcacg
    63781 attgaaaatg cacagaaatt aaaccattat tgggaagatg tgcgcatgta ttacaaaccg
    63841 tttgaaaacg gcttgaatgc tcctgaaaca gaagtatata tgcatgaaat gccaggagga
    63901 cagtattcga atctacagca acaggcaaaa gctgtcggat taggtcatcg ctgggatgaa
    63961 atcaaacaaa tgtatcatac tgtcaacttg atgtttggcg atatcgttaa agtaactcca
    64021 tcatctaaag tagttggaga tatggcacta tttatggtcc aaaatgatct tacagaagaa
    64081 gatatttatg aaaaaggcga aacactaagt ttccctgaat ctgttgtgac tttcttccaa
    64141 ggagaactag ggcaacccgt tggcggattt cctaaaaaat tgcaaaagat tattcttaaa
    64201 ggcagacctg cattgaatga acgtccaggt cttttggctg aatcagtcga cttcaacgaa
    64261 gtaaaaaaag aattggcaga aaaaattggc tatgaaccaa aacaagacga agtattaagc
    64321 tatttgatgt atccgcaagt ctttttggac tatcaaaaag catataatca atttggcgat
    64381 gttacattac tggacacacc aacatttttc caaggtatac gtttgggtga aacaatcaat
    64441 gtacaaatcg aacgcggaaa aacgcttatc attcgtttag atgaaatcgg agaacccgat
    64501 atcgaaggga atcgcgtact gttcttcaat ttgaatggac aaagacgtga aatcactatc
    64561 aaagataatt cgatcatcag tacggtccaa acccgattga aagctgaacc gacaaaccga
    64621 gaacaaattg gagcaacgat gtctggttct gttttggatg tattagtgaa aaaaggcgat
    64681 aacgttaaaa aaggtgatac gttgatgatt actgaagcga tgaaaatgga aacggccatc
    64741 gaagcacgtt ttgacggaga agtcgcacat gtatatgtgt cttcaggaga cactatttcg
    64801 tctggtgacc ttttgattga agtgactgag aaataataag cgaaaggtgg ggaaacatga
    64861 aaagactggg tttgttttgg ctgattctgc tattagttat tgtggcattc tacatggaac
    64921 cagtcttgtt tccgccaaaa cttgaagtga aggaaaactc tgatcaacaa atatcaaacc
    64981 aaatgacaac gtggaaatac caggagctta aagcaactgg tttttctact tatatcggaa
    65041 aaccgatcga tcagctggaa aaggattttg gccaagccta tgatcgatta actagcggat
    65101 ttggttttga aacaagatat tatgaaaata aagctagtca tctcacattt gaagcgaaca
    65161 tccaagacag cagagtcaca actgttaaag tactgcaaac agggcctgct gatatcgcgc
    65221 cgttttattt agggatgacg atgcaagatc ttacgaaaat cactactatc tatactaatt
    65281 tcacttttga gtaccatgat acagaagttg gaatcgaact aatggaagag gatatgaatt
    65341 atcgtccgct aattgctttt gataacgaca cttttgctat tttatttttt gatcaaacaa
    65401 caaacggcct attttcagtt gtgtatttag ataaagatag tcttttgaaa ctattgccat
    65461 atcaagtgtt tggtgaaggc cttccacatt atcaagcaga taaatcggct gattgggaat
    65521 caatcaatcg cgttaaagaa cgaaaaagta cgactttatt aaatatgctt agaagagaag
    65581 acgaacttcc catatacaat caaacacttg cctttcaaaa ccacagtcag ctgctactac
    65641 atgatttttt gacaaggcct gaggaaatat tgtcagagga acgtatggct gattggcaaa
    65701 aatcgctagg cagtgctcaa acgacagtga aattctcact gacgaatgat gaattggaga
    65761 agttaatcag taaacaaaaa ttagaaaata ctagtgggct atttattcat ccggcgattg
    65821 acgctacttt ttcgttttta tattggtaca gcgatcctta caaccatgac cgtttcatgg
    65881 acccgggaac ggattctgta ggcattgctt tttctaaaga aaatatgtta gtcttattgc
    65941 aagaagaaaa cggagaaagt agtgatagca gtgatcgtta acgaagagct gtttcaactg
    66001 gaggatcaat gcctccaagt cgctgaaatg ataaaaaaga gtaaaacgat ggcttcttat
    66061 cttgaacata aacagtcaat ggaagaatct gcaaaagttt gccagttgaa agaagcgttc
    66121 ttgtctaaga aagaagcatt tgaaaatgta gcggcatatg gtgagtatgc acctgattat
    66181 cgtgaaaaaa aacgagctgt tcgaaaagca aaaagacagc ttgatatgga tgagcatgtt
    66241 gcagctttcc gatatagtga aacacagctg caaagtctgt tggatcaaat tgtccaagta
    66301 cttgccgaag aagtttctaa tgaaatcaaa gtagatgcag gtagcccgtt ttttgaaacg
    66361 aaaaaacact ttggatgcgg aggtaattgt catgcaatta gacaatagtg aatttgaaat
    66421 aacaaaacga cgcgggctga tcgtatgggt ctacagctta aaacaattaa agaatctgaa
    66481 aaagttcggc ttgttgcatt atgtctcaag aagaatgaaa tatgtcgtgc tttacttaaa
    66541 tgaagagaca ttggaagaaa cagaagaacg aatccgtaaa ttacattttg ttcgaaacgt
    66601 agaacgttct taccgaccgg atatcgaaat gaattttgcc gaaaaaatag gaaacaaaac
    66661 agtattaaaa gacgaaggtt tcgaaattga agagctaaat acagaaatcc gattagctga
    66721 acatctttaa aaatctctta tgagcagttt ttaaataaaa aataacttgg ataacgatcg
    66781 atttttgatc attgtccaag tatttttttg gtatactagt accagtacca tttctaagga
    66841 gtgagtagat gcggataata tcaggaaatt atggcgggcg ccgtttaaaa agtttagcag
    66901 gggcgaacac cagaccaact acagataaag taaaagaatc catattcaat atgattggac
    66961 catattttga tggagagaca gtattggatc tgtttgcagg aagcggtggt ttagctatcg
    67021 aagcagtatc tagaggctgc agtcatgcgg tatgcgtaga caaaaattac caagcgctaa
    67081 aaatcatcaa agaaaacatc gaaattacga aagaaccaga gaaatttacc acaataaaac
    67141 ttgatgcgga caaagcaatc gaacggctag cagcggagaa acaacaattc gactacttgt
    67201 ttcttgatcc gccatatgca aaacaaaaaa taatcgatca aatccataaa atggaagaac
    67261 tgggactttt ttctaaaacc gcagttatcg tatgcgaaac ggataaaaca gtcgaattgc
    67321 cagaaactgt ggctggattc catcaaataa gaaaacagat ttatggcata acggccgtaa
    67381 ctatctatag aaaagaggga aatcaatgaa acgtgcatta ttcccaggaa gttttgatcc
    67441 ttttacaaaa ggtcacttag atacggtgga acgtgcggct aaattattcg atgaggtagt
    67501 aattggtgtt tttatcaata cttcaaagaa aagtttgttt cccccagaag aaagaatgac
    67561 attgatcaca aaagctgttt ctcatcttcc taatgtaaaa gtcatgcatc aagaaaatca
    67621 attgacggta gaaacagcaa aagagattgg tgcagatgcg ttgatcagag gcatacgaag
    67681 tatcaaagac tttgaatatg aacgagagat tgctcagatg aatcatcatc tatatgatga
    67741 attggaaact gtcttcttat tagcaaaacc agaatatagt cacgtgagtt ccagtatttt
    67801 aaaagaagta ctgcactttg gcggagatgt gagcagctac ttaccgccag tgatcaacga
    67861 agctttagct ggaaagcgtg aatcaaatga aagctaaaca atggttgaaa acagtactga
    67921 ttatcatatt tggaatgttg atcattggat ttgtagtagt tcccttgccg tattatgtag
    67981 aatcaccggg agccacgatc gatctgaaag aactaattac ggtcaatgat aaggaagata
    68041 aaggttctgg gtctttctct cttacctctg ttggtatcag gcaagctaca ggtttcttag
    68101 ctttaaaagc taaaatgacc ccttttgaag aattgatcag tgaagaagaa ttgactggtg
    68161 gggcgacaaa tgaagaatat aatcaaatgc aacagtatta tatggattct tcccaaaatg
    68221 cagcaatcga acaagcgtta aaacttgcag acaagcctta taaaatggaa ttcaaaggcg
    68281 tatatgtcat gagtgtagag aaaacatcga atttctttgg caagctttca gttggagata
    68341 cagtaacaaa agtagacggg aaaagctttc aaagtacaga agcatttatg gattatgtaa
    68401 aaagccaaaa agttggacaa acaatcgaaa tcagttattt gcataatggt gaagaaaaaa
    68461 cagcttctgg tgatctgatc gagttaccaa cagataaaaa ggcaggaata ggtatcacgc
    68521 ttactgacca taccgagatc gaatcagata cagatgttcg tattaattct ggctctatcg
    68581 gtgggccatc agcgggattg atgttcactt tagaaatcta tgaacaagtc actggtaaaa
    68641 acttgcgaca tggtaagcaa attgcaggaa ctggaacgat caacagtgaa ggagaagttg
    68701 gccgaatcgg aggaatcgat aaaaaagtgg caagtgcgga taaagctggc gtagagattt
    68761 tctttgcacc agatgatacg atttcagacg atgttaagaa agaatatcct gaaataaaaa
    68821 ccaactacga agaagcaaaa gctgccgcta aaaaattgaa ttcctcaatg aaaatcgtac
    68881 cagtaaaaac agtacaagaa gcgcttgact atctagagaa aatgaaatga aactaaat
//
LOCUS       DBBGSZ010000012        66292 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.012, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000012 DBBGSZ010000000
VERSION     DBBGSZ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 66292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66292
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.012"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            476..1339
                     /locus_tag="ACIZE5_001080"
     CDS             476..1339
                     /locus_tag="ACIZE5_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGC6108239.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="ACIZE5_001081"
     CDS             complement(1468..3090)
                     /locus_tag="ACIZE5_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGC6108240.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="ACIZE5_001082"
     CDS             3339..3860
                     /locus_tag="ACIZE5_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HGC6108241.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="ACIZE5_001083"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="ACIZE5_001083"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HGC6108242.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="ACIZE5_001084"
     CDS             5941..6759
                     /locus_tag="ACIZE5_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HGC6108243.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="ACIZE5_001085"
     CDS             complement(6862..7059)
                     /locus_tag="ACIZE5_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108244.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="ACIZE5_001086"
     CDS             7228..7806
                     /locus_tag="ACIZE5_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HGC6108245.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7901..8038
                     /locus_tag="ACIZE5_001087"
     CDS             7901..8038
                     /locus_tag="ACIZE5_001087"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108246.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(8851..9354)
                     /locus_tag="ACIZE5_001088"
     CDS             complement(8851..9354)
                     /locus_tag="ACIZE5_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGC6108247.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9713..10738
                     /locus_tag="ACIZE5_001089"
     CDS             9713..10738
                     /locus_tag="ACIZE5_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HGC6108248.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            11061..11939
                     /locus_tag="ACIZE5_001090"
     CDS             11061..11939
                     /locus_tag="ACIZE5_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase domain-containing protein"
                     /protein_id="HGC6108249.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12415..12531
                     /locus_tag="ACIZE5_001091"
     CDS             12415..12531
                     /locus_tag="ACIZE5_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HGC6108250.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13459..13797
                     /locus_tag="ACIZE5_001092"
     CDS             13459..13797
                     /locus_tag="ACIZE5_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108251.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13891..14121
                     /locus_tag="ACIZE5_001093"
     CDS             13891..14121
                     /locus_tag="ACIZE5_001093"
                     /inference="COORDINATES: protein motif:HMM:NF042636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6568 family protein"
                     /protein_id="HGC6108252.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14521..14892
                     /locus_tag="ACIZE5_001094"
     CDS             14521..14892
                     /locus_tag="ACIZE5_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HGC6108253.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(15166..15858)
                     /locus_tag="ACIZE5_001095"
     CDS             complement(15166..15858)
                     /locus_tag="ACIZE5_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC6108254.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15861..16646)
                     /locus_tag="ACIZE5_001096"
     CDS             complement(15861..16646)
                     /locus_tag="ACIZE5_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGC6108255.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16883..18283
                     /gene="lacG"
                     /locus_tag="ACIZE5_001097"
     CDS             16883..18283
                     /gene="lacG"
                     /locus_tag="ACIZE5_001097"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGC6108256.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            18308..18625
                     /locus_tag="ACIZE5_001098"
     CDS             18308..18625
                     /locus_tag="ACIZE5_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGC6108257.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18638..20311
                     /locus_tag="ACIZE5_001099"
     CDS             18638..20311
                     /locus_tag="ACIZE5_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HGC6108258.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSGMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            20325..21956
                     /locus_tag="ACIZE5_001100"
     CDS             20325..21956
                     /locus_tag="ACIZE5_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-beta-1,4-galactanase"
                     /protein_id="HGC6108259.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(22447..24012)
                     /gene="guaA"
                     /locus_tag="ACIZE5_001101"
     CDS             complement(22447..24012)
                     /gene="guaA"
                     /locus_tag="ACIZE5_001101"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HGC6108260.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(24071..24994)
                     /gene="coaA"
                     /locus_tag="ACIZE5_001102"
     CDS             complement(24071..24994)
                     /gene="coaA"
                     /locus_tag="ACIZE5_001102"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HGC6108261.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            25190..25795
                     /locus_tag="ACIZE5_001103"
     CDS             25190..25795
                     /locus_tag="ACIZE5_001103"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC6108262.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            26103..27119
                     /locus_tag="ACIZE5_001104"
     CDS             26103..27119
                     /locus_tag="ACIZE5_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6108263.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            27260..28561
                     /locus_tag="ACIZE5_001105"
     CDS             27260..28561
                     /locus_tag="ACIZE5_001105"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HGC6108264.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            28607..29269
                     /gene="deoC"
                     /locus_tag="ACIZE5_001106"
     CDS             28607..29269
                     /gene="deoC"
                     /locus_tag="ACIZE5_001106"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HGC6108265.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            29290..29688
                     /locus_tag="ACIZE5_001107"
     CDS             29290..29688
                     /locus_tag="ACIZE5_001107"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGC6108266.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            29754..30836
                     /locus_tag="ACIZE5_001108"
     CDS             29754..30836
                     /locus_tag="ACIZE5_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC6108267.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            31048..32610
                     /locus_tag="ACIZE5_001109"
     CDS             31048..32610
                     /locus_tag="ACIZE5_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6108268.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            32603..33736
                     /locus_tag="ACIZE5_001110"
     CDS             32603..33736
                     /locus_tag="ACIZE5_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6108269.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            33736..34692
                     /locus_tag="ACIZE5_001111"
     CDS             33736..34692
                     /locus_tag="ACIZE5_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6108270.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            34791..35957
                     /gene="deoB"
                     /locus_tag="ACIZE5_001112"
     CDS             34791..35957
                     /gene="deoB"
                     /locus_tag="ACIZE5_001112"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HGC6108271.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            35981..36799
                     /locus_tag="ACIZE5_001113"
     CDS             35981..36799
                     /locus_tag="ACIZE5_001113"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGC6108272.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            36816..37523
                     /gene="deoD"
                     /locus_tag="ACIZE5_001114"
     CDS             36816..37523
                     /gene="deoD"
                     /locus_tag="ACIZE5_001114"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGC6108273.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(37821..38507)
                     /gene="gpmA"
                     /locus_tag="ACIZE5_001115"
     CDS             complement(37821..38507)
                     /gene="gpmA"
                     /locus_tag="ACIZE5_001115"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HGC6108274.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(38679..39260)
                     /locus_tag="ACIZE5_001116"
     CDS             complement(38679..39260)
                     /locus_tag="ACIZE5_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6108275.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(39393..40076)
                     /gene="rpiA"
                     /locus_tag="ACIZE5_001117"
     CDS             complement(39393..40076)
                     /gene="rpiA"
                     /locus_tag="ACIZE5_001117"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HGC6108276.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            40395..40808
                     /gene="rpsL"
                     /locus_tag="ACIZE5_001118"
     CDS             40395..40808
                     /gene="rpsL"
                     /locus_tag="ACIZE5_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HGC6108277.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            40892..41362
                     /gene="rpsG"
                     /locus_tag="ACIZE5_001119"
     CDS             40892..41362
                     /gene="rpsG"
                     /locus_tag="ACIZE5_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HGC6108278.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            41456..43543
                     /gene="fusA"
                     /locus_tag="ACIZE5_001120"
     CDS             41456..43543
                     /gene="fusA"
                     /locus_tag="ACIZE5_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HGC6108279.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            43715..44902
                     /gene="tuf"
                     /locus_tag="ACIZE5_001121"
     CDS             43715..44902
                     /gene="tuf"
                     /locus_tag="ACIZE5_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGC6108280.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            45309..45617
                     /gene="rpsJ"
                     /locus_tag="ACIZE5_001122"
     CDS             45309..45617
                     /gene="rpsJ"
                     /locus_tag="ACIZE5_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HGC6108281.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            45648..46277
                     /gene="rplC"
                     /locus_tag="ACIZE5_001123"
     CDS             45648..46277
                     /gene="rplC"
                     /locus_tag="ACIZE5_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HGC6108282.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            46305..46928
                     /gene="rplD"
                     /locus_tag="ACIZE5_001124"
     CDS             46305..46928
                     /gene="rplD"
                     /locus_tag="ACIZE5_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HGC6108283.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            46928..47218
                     /gene="rplW"
                     /locus_tag="ACIZE5_001125"
     CDS             46928..47218
                     /gene="rplW"
                     /locus_tag="ACIZE5_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HGC6108284.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            47257..48090
                     /gene="rplB"
                     /locus_tag="ACIZE5_001126"
     CDS             47257..48090
                     /gene="rplB"
                     /locus_tag="ACIZE5_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HGC6108285.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            48133..48411
                     /gene="rpsS"
                     /locus_tag="ACIZE5_001127"
     CDS             48133..48411
                     /gene="rpsS"
                     /locus_tag="ACIZE5_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HGC6108286.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            48434..48781
                     /gene="rplV"
                     /locus_tag="ACIZE5_001128"
     CDS             48434..48781
                     /gene="rplV"
                     /locus_tag="ACIZE5_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HGC6108287.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            48795..49451
                     /gene="rpsC"
                     /locus_tag="ACIZE5_001129"
     CDS             48795..49451
                     /gene="rpsC"
                     /locus_tag="ACIZE5_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HGC6108288.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            49454..49888
                     /gene="rplP"
                     /locus_tag="ACIZE5_001130"
     CDS             49454..49888
                     /gene="rplP"
                     /locus_tag="ACIZE5_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011375443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HGC6108289.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            49878..50066
                     /gene="rpmC"
                     /locus_tag="ACIZE5_001131"
     CDS             49878..50066
                     /gene="rpmC"
                     /locus_tag="ACIZE5_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HGC6108290.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            50091..50357
                     /gene="rpsQ"
                     /locus_tag="ACIZE5_001132"
     CDS             50091..50357
                     /gene="rpsQ"
                     /locus_tag="ACIZE5_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HGC6108291.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            50415..50783
                     /gene="rplN"
                     /locus_tag="ACIZE5_001133"
     CDS             50415..50783
                     /gene="rplN"
                     /locus_tag="ACIZE5_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HGC6108292.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            50820..51128
                     /gene="rplX"
                     /locus_tag="ACIZE5_001134"
     CDS             50820..51128
                     /gene="rplX"
                     /locus_tag="ACIZE5_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HGC6108293.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            51156..51695
                     /gene="rplE"
                     /locus_tag="ACIZE5_001135"
     CDS             51156..51695
                     /gene="rplE"
                     /locus_tag="ACIZE5_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HGC6108294.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            51714..51899
                     /locus_tag="ACIZE5_001136"
     CDS             51714..51899
                     /locus_tag="ACIZE5_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HGC6108295.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            51935..52333
                     /gene="rpsH"
                     /locus_tag="ACIZE5_001137"
     CDS             51935..52333
                     /gene="rpsH"
                     /locus_tag="ACIZE5_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HGC6108296.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            52365..52901
                     /gene="rplF"
                     /locus_tag="ACIZE5_001138"
     CDS             52365..52901
                     /gene="rplF"
                     /locus_tag="ACIZE5_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HGC6108297.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            53062..53418
                     /gene="rplR"
                     /locus_tag="ACIZE5_001139"
     CDS             53062..53418
                     /gene="rplR"
                     /locus_tag="ACIZE5_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HGC6108298.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            53439..53939
                     /gene="rpsE"
                     /locus_tag="ACIZE5_001140"
     CDS             53439..53939
                     /gene="rpsE"
                     /locus_tag="ACIZE5_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HGC6108299.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            53954..54133
                     /gene="rpmD"
                     /locus_tag="ACIZE5_001141"
     CDS             53954..54133
                     /gene="rpmD"
                     /locus_tag="ACIZE5_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HGC6108300.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            54177..54617
                     /gene="rplO"
                     /locus_tag="ACIZE5_001142"
     CDS             54177..54617
                     /gene="rplO"
                     /locus_tag="ACIZE5_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HGC6108301.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            54617..55912
                     /gene="secY"
                     /locus_tag="ACIZE5_001143"
     CDS             54617..55912
                     /gene="secY"
                     /locus_tag="ACIZE5_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HGC6108302.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            55974..56621
                     /locus_tag="ACIZE5_001144"
     CDS             55974..56621
                     /locus_tag="ACIZE5_001144"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HGC6108303.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            56812..57030
                     /gene="infA"
                     /locus_tag="ACIZE5_001145"
     CDS             56812..57030
                     /gene="infA"
                     /locus_tag="ACIZE5_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HGC6108304.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            57063..57179
                     /gene="rpmJ"
                     /locus_tag="ACIZE5_001146"
     CDS             57063..57179
                     /gene="rpmJ"
                     /locus_tag="ACIZE5_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HGC6108305.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            57197..57562
                     /gene="rpsM"
                     /locus_tag="ACIZE5_001147"
     CDS             57197..57562
                     /gene="rpsM"
                     /locus_tag="ACIZE5_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HGC6108306.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            57590..57979
                     /gene="rpsK"
                     /locus_tag="ACIZE5_001148"
     CDS             57590..57979
                     /gene="rpsK"
                     /locus_tag="ACIZE5_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HGC6108307.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            58059..58997
                     /locus_tag="ACIZE5_001149"
     CDS             58059..58997
                     /locus_tag="ACIZE5_001149"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HGC6108308.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            59025..59405
                     /gene="rplQ"
                     /locus_tag="ACIZE5_001150"
     CDS             59025..59405
                     /gene="rplQ"
                     /locus_tag="ACIZE5_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HGC6108309.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            59677..60516
                     /locus_tag="ACIZE5_001151"
     CDS             59677..60516
                     /locus_tag="ACIZE5_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HGC6108310.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            60492..61361
                     /locus_tag="ACIZE5_001152"
     CDS             60492..61361
                     /locus_tag="ACIZE5_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HGC6108311.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            61351..62148
                     /locus_tag="ACIZE5_001153"
     CDS             61351..62148
                     /locus_tag="ACIZE5_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGC6108312.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            62351..63097
                     /gene="truA"
                     /locus_tag="ACIZE5_001154"
     CDS             62351..63097
                     /gene="truA"
                     /locus_tag="ACIZE5_001154"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HGC6108313.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(63552..66221)
                     /locus_tag="ACIZE5_001155"
     CDS             complement(63552..66221)
                     /locus_tag="ACIZE5_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HGC6108314.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFFYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
BASE COUNT        21025 a        11916 c        14044 g        19307 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgtgacttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacgt cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ataaatatta
     8281 acgtgttttc aaacagtata aaacggtgtg gtttttggaa taaaaaaata acatatctca
     8341 ttttacactt ttgttatttt atacttaaaa aataacgaca cagaaaatac cgtgtctcag
     8401 atttctctac tacttctaaa aactactgtt tttttccttt gaaatgcctt caaaaagtag
     8461 gatcaggcag aatatactgg cagaatcaag gagaagggag cctaaataag gagaaaaacc
     8521 atagaaaata taaagtaatt acttataaaa caagcttttt atagaaaaat aatatacctg
     8581 agtagggtat aaattaagac ggaattcctt tctagattga gatattgact aggaagaatg
     8641 ttaagatttt aagcctttaa gctaaaaaaa aacccttttt gttaaataag gggaatatag
     8701 cctgtcagtt tcaaactgca agtcgtcctg ctgcaataat atagtagatt agagatgaaa
     8761 atagattttt ttaaaccaat gactgaataa aaagaccgtc atagatacac attggaatgt
     8821 gtctattacg gtcttttttt acgaacgatt ttattgaaga cggacagttc gggtcaaaaa
     8881 taaaaaagct acgatcagaa ataagaataa aatgtatccc aaaataatgg ctagacggtc
     8941 taacttattt gtcgatagat gtttgtttag aagttgatag gcccataaac ctatcagtcc
     9001 tcctgttgta ttagttatca aatcagtgat gtccgctacg ccaataccga ataggaattg
     9061 aatcaattct gccaagaagc ttacaaggaa aataatccct aattttttag aaaaagaaag
     9121 tctcttgaaa ttgacattca aaagcacccc aaaaggaaaa aagacaatca agttataagt
     9181 ggtctcacgt aataccgtcg tattttcaaa agaaaaagta gaaaaaggga cgagattgac
     9241 attgctgtaa gaataagtga gaaattgtgg aagattaaat gatagcttga ataaaatcaa
     9301 ccataataga aagaataaat aaatccctaa taaaaatttt gatacatacc gcatagacat
     9361 ctcctccatt taaaaagtat accatcgaaa accgctgaaa aatcataaaa aagtatgaag
     9421 tttaaggacc aacgtagtta tcgtacgaaa attagaagct tttttttgtt gggaatccgg
     9481 tttctttaac aaagctaaga tagcgagttg cttggaaaag ttgctatctt ttttctgtca
     9541 aaacgactcg gaatgttcgt tttttgttct aatttctcca agttgtttac tttttgatac
     9601 taagtttatg aaaaatcaag aaatagttgt tatactaggt aatgctgaca aacgggattg
     9661 gcatttcatc ttggttcagc tttttttcca attactagga aggagggata gattgttcaa
     9721 gacttatttt cgtttcaata aaatacaaga taatcctttt cgtatcatga atctgatgct
     9781 acttatcttt attgtattat ggttaggtta cataaatcat gattttttga tttcaagttt
     9841 ttcatcatta gggatcttta cttttttcta ttatcaaaac ataccgatga aatatttgct
     9901 gaaacgtatg tttctgatcg gttgcggact gttggttgct ttcgttttgg ggatcttatc
     9961 gacttatgtt ttatggcttg aaccatttgc cgtagctttg gttgcttttt ccagcagatt
    10021 cgtgttgcga ttattccata tttctaaacc aggtggcttg ttttttgcga tgctttctgc
    10081 catgggaacg agcatgcagc tgccaatcgc tcaattaccg atcgtctcac tttatttttt
    10141 tatgggtgtc gtttttgccc tgattgcggc agtgattaca aaattactgg attcacggcc
    10201 tgagcagaca attgaaaaag caactttaaa agaaagattt cacgaagagc ctttagtgat
    10261 cattgattct gttttctaca gcgctgcctt atttctttcc gtttatgtca gtcacggctt
    10321 gaatctgcat aatccttatt ggttgacctt gtcatgtgca tcgattttgc tagcagaaaa
    10381 cttggatgcg atgaagcatc gacaagtcca atatctgatt ggatcgatgg gtgggttatg
    10441 tgtgtcggca ttcttgtcat ttgtgccgtt tacgcagttg cagaccattt ttctgatcac
    10501 ttttctatat ggaatcgcac aatttctagt tgctagaaat tatgcagttg ctaatatttt
    10561 tcttaatccg atggcgttga tgctatctac acttattcgt ggagcatact tgatttcttt
    10621 gatcgaatat cgttttttag ggatcgtcat aggaagtttc atcggtttag gtgttgcgtg
    10681 ggtaatgacg gttggtttgc aacattattt aacggttgtt cgtcaaaaat tagaatagaa
    10741 ggacaaatat atgtgccaaa agaggttatg acaagatttt tgtcacaacc tctaattcaa
    10801 ggtgttcaaa agccagattc tcagcattaa gtcaaattca cacaaaaatg tggaaaggaa
    10861 ctttcaaaaa aattttatat ttattctatc aaaaaatttt gtttatgatg gtaactgaat
    10921 aaactttcct gagatggtca atgctttcct tgaaagtctt acagatattc tttcttcata
    10981 gaaagtttaa gttttatagt tagtgtacaa taaaagtatg tttataccat atggtgtccg
    11041 gataatcagt catttaaaca atgaggttca aagatatgaa aaggggaaat ttgatgaaga
    11101 aaataagcaa tgaaatccaa attctggcag aaactttaac tcttcccaaa gtcgttatag
    11161 agcaaatgat tgtacaagca aaaaacatcc ttgatgaggt gtttgagcaa tatagtcatg
    11221 aactaatgga tcctaataaa gcaaaggcga ctgcaaagaa aatagacaaa gtctatgaag
    11281 aggaaccttt tgcagcatta gctatttatc tatatgcagc ttctcaaagt tggaaaaaaa
    11341 tttatcaacc attgaagatt ccaagaacta tctatttggc aacaatgaat gcttttacta
    11401 gatttattca tgaacatttc caagtaacag gaagctatcg ctttgaccgt ggtttttgga
    11461 tttggcatta cactagtggc ttgatctttc ggattggtga attggagtac gaaatgacat
    11521 attttccgaa agggtacacg gatctaagat tagaaggaaa gcagtgcctt tctcttcata
    11581 ttccttccga tgcagattta tctcagaata agataagaga tagttacgaa agtgccattc
    11641 gtttttttga actttatttt cctgattacc attaccaagt gatgtacaca gatacttggt
    11701 tactatcacc caatcttact aaatggttga aaaaagagtc aaaaatctgt ctttttgcag
    11761 ccgattatcg attattatca gttgatgaac aggacgatag tggagtccct tggatctttg
    11821 gacgagtaga tgcccaaata catgattatc cagaaagtac gagtttacag cgacaagcaa
    11881 aagagcaatt gcttgcaggc gagcacattg gctctggctt aggtattctt acttcataag
    11941 tttagtactt cgaaatagtt taaaagagcg tgagacaaaa gtaaagaaca cttttgtctc
    12001 acgctctaaa cacgtataaa cggcggaagc agaagcaact ccttcggaaa taagctgaaa
    12061 ttcacaaaaa tttgaaaagc aattttcgtg aatttcttct tatttcttgg agttaaacgc
    12121 ttctgtccca gcctcttttt tagtgttcta tcgaacacac agtacgttca ataggtaaac
    12181 tagctataac aatagatatt aaagttaacg gacaagaggg ccttttttag gtagctaaaa
    12241 cgtaataatg aaaatttatt tccagagata ggagtcaatc agctagtctg atcgactgtt
    12301 ttaacaagtt gactttcatt ttaacttttg ataccattta aaacacaaat cgtaattgtt
    12361 tcgatttgtg ttttttagca tgactacaat caaagaagaa agtgggtcgt ccatatggaa
    12421 aaaacagata tctcaagtgc ataccgccgc ttgaaaagcc caaatatcaa aacacgaaaa
    12481 cgtgcgctga agatcatcaa agatgtgaaa cggaatagtg ggaaaaggta agaagaagga
    12541 aacttaatta aaaaaatagc cgaaaaacgt ttttcggcta ttttcaataa tcggtttttg
    12601 tgtaaggttt ccgaaagaac tgctgttgat tttccatttt taacatatga taaattggta
    12661 gaatctttct tttcaaattg ataccattcc ctaattccag ttatatagtt aactacagaa
    12721 ccacaaagca cgtacgttta taaaagtatt atctgtagtt atttttcaat tccctttcaa
    12781 cctcttattt tgaccagtag tattgatcac tttacctttt aacacctttg ttcgtttttg
    12841 aaacattttt agtcaagaat ggaaacgtaa ctacataatc aaaggttttg cgaaatattt
    12901 catgaaatat ttcatgtaga agcgagcaat acggttgcaa ataaccatta tcgtttaata
    12961 agcagttacg aaagctccca atatctctaa cgttcagctc actccatttc ttttcttcaa
    13021 aaaaatcagt gattcgtatc tctttctatt tgtcgaaaaa gttaacttta aaaagtaacg
    13081 ccgaaaaaat atgcaaaaaa ataaaaaagc agttactatt gctagaataa catcaaggaa
    13141 taataagttt tggttttcag ataatagtcg ataagttgtg tattggaatt ttagatacag
    13201 taataaagta tttttcatga aattttgtga gaatcactat tacaagtatc tttaataaaa
    13261 ttaatggtta aggaggaact taaagtagaa tgtaaatgaa tagttgtagt cagtcgattg
    13321 tgatactaga ctcaaagttg caggaataag tttttcaatt tgtgattgga agataaaaaa
    13381 tgaaaaagaa gggctttttt ttatactttg ttgattgtag tgtttatttt ccctctgttt
    13441 agccaagtaa cattttctat gactcaacca gtttcaagtg aggaacatga taaccttttt
    13501 cgtgctacag aagagtttaa gaaatatcag gaaaatattg ttccggagac tccattagct
    13561 agtgagccaa ttactgatat tgatggaaac caaataggat ggtatataca gtacgaagtt
    13621 atggtggtaa ataatgactc aatagtaaaa aatacagtag gcttagagct aacaccgatt
    13681 gaaaaggtga gttcattgtt aacgtatatt tatactgatg aaagtgacga gactgagatc
    13741 attttaacgg attactcaaa aattgctact gataaaaagt atatattgtg gatgtagaca
    13801 ctagtgaaat actttatgat atagaaattg atgaaaattt actagatgta gcacaagaaa
    13861 tcgatcatca aaagcaggaa gctattcgat atgctggtag aaaagggaaa agaaaatatt
    13921 tattacgtga atgtagcaaa agttagagaa gatgaaaatg agtggaaaga attcaagagt
    13981 cgctactcaa ttaactcgac tccgacattt acagtttaca gagaaggatc gatagaaaaa
    14041 actgtttttt ggactaaaga aagtggaatg tctttagctg aagtagaaga gtttttggat
    14101 tatgttagta tgcaacagta agggagttct tattatgaaa aattttgaca catattatgt
    14161 tattgttttt tcgatatctt tgctgttaat attactaact ttaatgcagt ataaagagta
    14221 tccagagtat tttattttaa cttttgtata tttagtaagt agctacacac ttctatataa
    14281 attcagaagt tcttctagag tttctaaagt ttgtttctta attagcttat tgattctata
    14341 atatttttga tttatatagg aaattaaaaa tattatagaa tcaacactca gagaacgggt
    14401 tggtttttaa tagatttaat aagtactgat aatgaaattt ctcctggttg ggaaaacgaa
    14461 gttggttacc ctgtagaaga attttttcaa gattactttg cggagtatgc cgataggata
    14521 atgagagatt acgtaacaga taaaactcaa gaagtcatca atcaatccca gtcattaaat
    14581 gaattatctg ataaggcgaa agaagaagca gttgccatta tttcttcagg gattagtgac
    14641 tatattgata tgagtggtga aatcaattat ggcgataaag acaaaattgt acgcatgata
    14701 aaagctttta tcaaaacttt tgatgtgaag gcagatctta agtttaatga tacttaccta
    14761 gtaggaaaat taattaatat ccttgggaca gagaaagata cggaaacgtt tatttcctct
    14821 ttgtctatgt tgtttacaga taagcatttt tcaactcagc ttggtggaga ggaactagtg
    14881 gaaatctttt aaccattacg cccagcatta ataaaagtat atcaaaaaag tactcctgat
    14941 gatttttaag attggtttga gaaataatgt gaaaacacta tttttaatgt taattataga
    15001 tagagatgaa cgcgtcatat ggttaaaaga atgaaaaagt caaagataca ctgctatatt
    15061 tcactaagga tatagcagtg tatctttcat gtcgtttcac tggcagtttt ttataaaagg
    15121 aggtgtgcat ttcagttgct tttctttggt agttagttga atcgtttaag aattaacgga
    15181 tgtggcagac aggtgctctg tccaaaaacc agtaaaatct ttgatggttc catctttatt
    15241 tagctgtgcc tgttcaaata ctgttttgtt tttaccgaat ggatcaattg caataattgt
    15301 tccgatcccc gcacgtttgg cagcaagtaa tcctgagtaa gcatcttcga taacaagaca
    15361 atcagccgga gctaagctca gtttgtctgc cgctttaaga aaaatatccg gttgcggttt
    15421 cccagggaaa gagccgtcgt catagacaat cttgtcccag tcaaaccagc gggctaaatc
    15481 gaaaatatca aaataaaaag caacattctc tttgacagta gccgtggcaa tcgttaatgg
    15541 aatctgttgg tcagtcagct ggtcaagagt cgcttcaagc ccttttgtca actgaagctc
    15601 gttttcattt tgcaagcaaa gcatacgata atagctttct ttttcttctg acaatacggc
    15661 gatctcagag gcggtcaaat gctctgaaat gaaatgtttc aaaatctccg tattcgtccg
    15721 accatgaata ttttttaaaa tatcctcgtc tgataaacca tcttttgtat gatcatgtat
    15781 catatgcagc caagcagctt catgcagatg agagtccaaa aacattgttc cgttgaaatc
    15841 aaatataatc cctttcatag ttacgctcct atagtggtat tttcggttga atcagcaatt
    15901 tgcagatcga catattgtgc atagtgctct tgaacctccc gcgagatctg gcgatccgta
    15961 atgagcagat cgaaatcatg caaattataa aacacataaa aatcatctcg attgaatttt
    16021 ttattatcaa cgagtagata tttcttacgg gaattattta gagcgatctg ctgtgcttct
    16081 ccttcttcgg tactgtaagt agagatcgct tcgttgtgaa cgccatttga actgataaat
    16141 gcttttgtaa actttagtct tcttaaattg tcgttggtga tcggtccgac aaatgcgccg
    16201 gtatttttcc ggaaatcacc gccaatcagt agaatttctg gtccatctgc ttgagcaaga
    16261 atatcaaaaa ctggataatt atttgtaatg atccgaattt tcttgttcag taaatgcgtc
    16321 gccaatagtt cgattgttgt acctggtcct aagaaaatcg tttctccctc gtgaatcaag
    16381 gaggctgctg tggcagcaat ttcttttttt tcttgaatct gcagagtggc tttttcagtg
    16441 tgagaaagtt cttgatctaa agtgtaggaa agactttgag cccctccatg gacacgcagc
    16501 agcttgcccg atttttctaa ttcatctaaa tctctgcgaa cggtcatatc agaaacatct
    16561 aattgattga tgatttcatt aacggtaagg attccttttt tattgaccat ttctacgata
    16621 gtaagcaatc tttctttttt caacattgtc ttcacctcta atttaaggat aatctatcat
    16681 ataaacggac aacagtcaat ctaattcgaa caaaagtaaa catttagggt ggtttttatg
    16741 tttgttacaa tagattttat tgctgttttc tggtttttat gattatttgt gtttgttttt
    16801 gttgacaaat gttttggatg cgtttacaat gcaatcagtt agaaagagcg aaaactgatt
    16861 atagatttga ggagagatgt acatgcttaa attaccagaa gattttattt ttggcggagc
    16921 cacagcagcc tatcaggttg aaggagccac taaggaaggt ggcaaaggcg ctgttgcttg
    16981 ggatgacttt ttagaggaac aagggcgatt cagtcccgat ccggcaagtg atttttatca
    17041 tcaatatgca aaggacattg aattgtgtga acgttttggt gtaaatggtc taagattatc
    17101 cattgcttgg agccgcattt ttcctgatgg agctgggaaa ccaaatccag aaggaatcgc
    17161 tttttatcat cgtgtgttcg aagaatgtaa gaaaagaaac gtaacgccgt ttgtgacgtt
    17221 gcatcatttt gataccccta aacgtttgtt tgaccatgga gattttttga atcgagaaac
    17281 aatagaagca tttgtttcct atgccatttt ttgttttcat gaattcaaag aagtcaaggt
    17341 gtggagtacc tttaatgaaa tctatccagt tgcaaccaat caatatttgt taggtgtttt
    17401 cccaccagga atcaaatatg attttacaaa gatcgtcgcc tgtcttcata atatgatggt
    17461 tgctcatgcc cgtgtagtga actatttcaa agaaaacgaa cttccgggtg aaattggtgt
    17521 agttcactca ttagagacga aatatgcggc aacagacgcg ccggaagata agcatgctgc
    17581 ctttttagac gatgcattgt cgatccgttt cttattagat gctacctatt taggctatta
    17641 ttcaactgaa accttgactg ctcttgatga gatatgtgaa gcaaatcagg ccagctatca
    17701 ttttcctgaa gaagatttcg ttgaattgaa aaaagcatcc acgcgtaatg actacttagg
    17761 gatcaatcac taccaatgcc attttgtcaa agcttacgat ggagaaaatg caatccatca
    17821 taacggtacg ggtgaaaaag ggacctctgt ttataaagtg aagggaatcg gagaacgtat
    17881 ttataaagaa ggaattcctc gaactgattg ggactggctg atttatccag aaggtctata
    17941 tgacttgttg ctgcgaatta aaagcgatta cccacattac aacaaaatct atatcactga
    18001 gaacgggatg gggtataaag atcagtttga agatggcatt attatggatc agccgagaat
    18061 cgactatttg agagtctatt tggaatcctt aagcaaggcg ataacagccg gggtaaatgt
    18121 gaaggggtat tttttgtggt cgcttatgga tcttttctca tggacaaatg ggtataacaa
    18181 aaggtatggc ttgttttatg ttgattttga aacccagaag cgttacccaa aagaatcagc
    18241 ttactggtac aagttggtca gtgaaaccaa aacgattatt taataagtga taatggagga
    18301 agaaaagatg aataaagagg aattacaaat gcttggtttt gagatcgttg catattcagg
    18361 cgacgctcgc agtacattat tgaaattatt gaaagaagta agacaaggaa actttgaaca
    18421 tgttgattcg gcgttgaaag aagccgacga aaatttaacc cttgcacata attcgcaaac
    18481 aaaaatttta gcggaagaag catctgggaa agagatggag atgggattca tttttatcca
    18541 tgggcaggat catttaatga ccactttatt gctgagagat ctgattcaag actttattgt
    18601 actgtacaga cagaatcaag gataggagaa gaacgctatg gatggaatca ttaaacaaat
    18661 cgaaaaaggg aaaccatttt ttgaaaaaat ctcacgtaat agttatttag gagccgttcg
    18721 tgacggattt ttaacagcga tgccagctat tttattttca agcattttca ttttgattgc
    18781 tgcggttcct gagatttttg gttaccaatg gcctgaatct gtctccacat ggctatggaa
    18841 agtctataat tattcgatgg gtgttgtagg gttactcgtt tcagcaacca ctgctcgctg
    18901 cttggctgat tcgatgaatc gtcgcttacc gaaaaacaaa gtaatcaaca ccacctctgt
    18961 gatgctggcc tctgtggtaa gtttcctgtt gttaagcgtc tctccgattg aaggtggatt
    19021 ttcaacggaa tatatgggga caaagggact actggcttcc tttgtcgctg catttttaac
    19081 agttaattta tataagtttt gtgtgctgaa agatattacc attaaaatgc ctaaagaagt
    19141 tcctggaacg atttcgcaaa ccttccgaga tatttttcct ttctcttttt cagtatttgc
    19201 ggccgtttta attgatttag gcattcgaca aatcttccaa atctcatttg cagaagcaat
    19261 cattacggtg ctgcagccgc tatttacagc agctgacggg tacttaggaa tcgctattat
    19321 ctggggagcg atggcgctgt tttggtttgt cggtgttcat ggaccgtcga tcgtggagcc
    19381 ggcaattgcg gcaattatct atgccaatgt ggaaaccaat ctgcaattgt tcaattccgg
    19441 tgaacaagct tctaaagtac tgacggtggg tttagggaat tttgtaggaa ctatgggagg
    19501 aactggggca acattggttg ttccttttat cttcctactc tttgctaagt ctaagcagtt
    19561 gaaggcagtt gggaaagctt cctttattcc agtaagtttc gctgtcaacg aaccattgct
    19621 atttgcggca cccatgattt tgaaccctta tttttttatt ccatttttgt taacacctgt
    19681 tgtaaacgtt tgcctgttca agttttttgt cgatgtattg ggcatgaaca gctttatgta
    19741 cgttttgcct tgggcaactc cagcaccgat cggtttggtt ctaggaacgg gcatgggtat
    19801 cttagctttt gttctagcag cggttctaat cgtcgttgac ttcctgatct atctaccatt
    19861 ttgcaaagca tacgatgctg tcttagtaga gaaagaagca caaaaagcag aggtgatcgc
    19921 aaccgaggaa ggtgcttctg ccgatgtacg tgaggaagta cctgtggcag cgagtcaagt
    19981 tatcagcgat gcaaataaag aaatcaatgt gttggtactt tgtgctggcg cagggacaag
    20041 tgggatgtta gctaatgctt taaaaaaagg tgcatctgaa tcgaaagcac cgatcagtgc
    20101 aatggcgggt gcttatggtt ctcattacga aatgctgcag gattttgata tggtggtctt
    20161 agcaccgcaa gtcaattctt actatgatga tatcaaagaa gacaccgatc gcttaggaat
    20221 caagctggtt gcgacaaaag gagcagaata tatcggatta acgagagatc ctgaaaaagc
    20281 tgttcagttt attctgaacc aatttcaata aaggaggagc cataatgaaa atgggaattt
    20341 ggttgcgtaa agctgtttta tttgcagctg tgttaggggc tttgggggct gtttcaaaaa
    20401 ctgttgaagc atctgccagc gaatttattc gcggagcaga tatttcgatc ctgtcagata
    20461 tggaaaaatc tggtgcaaaa tattatgaag acgatatttc aaaagatgcc ttagagattt
    20521 taaaaaataa tggtgtcaac tatgttcgac tgcgtttgtg gcaggatcct tataatagta
    20581 atggagaaag ttatggagca gggacaaatg atctggaaac gacgattgac cttgcaaaac
    20641 gagcaaaaaa tctgggactt aaggtgctgc tggattttca ctacagtgat ttttgggttg
    20701 atcctgggaa acagaatctt cctaaagcat ggcaaggtct gacctttgaa gaaatgaata
    20761 cggcattgta cgactataca aagaacgttc tgtcggaaat gaagcagctg gacgtttatc
    20821 ctgatatggt tcagatcggc aatgaactga atagcggaat gctctggcct tatggcaagt
    20881 cttggggaga aggcggggga gaatttgatc gattggctgc ttttttgaag tctggtatcc
    20941 aagctgttcg agacactcaa cctaaaacaa ctccagtaat gctccactta gctgatggtg
    21001 gcgatacagg agcatttact tggtggtttg atgaaatcac gagtcgaggt gtgtcatttg
    21061 atttaattgg agtgtcgtat tatccgtatt ggcacggttc aatgaatgaa cttcaaacca
    21121 atatgaatgc gatcagccaa cggtatggta aagaagtgat cgtagttgaa acagcttatg
    21181 ggcatacaac agcgaatgcc gatactatgc caaatgcttt tggtgaagcc gaagcagctg
    21241 cggggggata tgaaccaaca ccgacaggac aagcagagta tttgctggat cttgccgatc
    21301 ggattcaggc agtaccgaat aatcgcgggg cgggcttctt ctattgggaa cctctttggt
    21361 acaacggaaa tgtgagttgg gcaacacaag caggtatgaa ttatctcagt gttcaatcca
    21421 ctatgggaaa cgaatgggac aaccaagcga tgtttgattt tgctggaaac gccttgccaa
    21481 gcttgcgtgc gtttaaacaa gcaggggcgc aaataaatct agttaaaaat gcaagtttcg
    21541 aaagcgatgg accaacgacc agtccttcca attggcaaac ctggtttcaa caaggaaccg
    21601 ctaagggtac gatcaaaacg gaagcgggca ctttttttgg ggactacaaa ctaacttttt
    21661 ggcaggatca agcatacgag gcatcagctt atcaaaatgt tagtggcata agcaaaggaa
    21721 cttacacatt gagtgcctat gtaatgtctg ggggagagtt tgatactaat cagttatata
    21781 tcaaaaatta tggtggagcg gaactaaata ctgcggttgt taaaacaagt gaatggacaa
    21841 aaattacaat caaagacatt ccaattacaa caggtgtttg tgaaattggg gtttatagca
    21901 aggcttcagg aaatgcttgg acgaacgttg attttgtttc attggtgaaa caatagactg
    21961 cggatcgttt cgattcaaga tcggaggttc ccttcagcca catcgttagc gtagaaggca
    22021 ggaatcgaac ctgcacctcg cctttgccaa aaataaccag aaacgatttc cagtcatttt
    22081 taccaaaacg agtaaagcac cagacttcat ctacactttg tattatgcta aagagagttc
    22141 aacgatttcg taagaagcaa tgaaaaaatt gcaaaaagtt gtgcagataa cataaagttt
    22201 gtttaagaaa gggtaacctt agaattccgt cgtgaatatg atttgagcac ttagatggat
    22261 agaaaaaagt tctcggaaaa cagttcgttt ttcgagaact tctttttatg ataagaatga
    22321 aacaaattaa cttatattat agtctctttt ggtagggaac catcttattt ttaatgaaaa
    22381 tcaagcattt tagctattga agaatgttga tttataggga ttccccctcc atattatgtt
    22441 ggctctttat tcccactcca ctgttgctgg tggtttagaa gtgatgtcat acacgatacg
    22501 gttgacgtgg gctacttcgt ttacgatacg tacagagatt ttttgcaaga cttcccatgg
    22561 gatacgggca aagtcagcgg tcattccgtc gattgaagtt acagcacgga taccgactgt
    22621 gtagtcgtaa gtacgtccgt cacccataac accgacagag cggatccctg gaagaacagt
    22681 gaaatattgc cagatatcac ggtcaagtcc agcagctgcg atttcttcac gcaagatagc
    22741 atcagattcg cgtacgattt ctagcttgtc ttcagtgatt tcgccaagaa cacgaatacc
    22801 aagaccagga ccagggaatg gctgacgcca aacgattgaa tcaggcatgc ctaactgagt
    22861 ccctaattca cggacttcgt ctttgaataa tgtgtttaat ggttcgatca attcaaattg
    22921 catatcttct ggcagtccac ctacattatg gtgagatttg atcgtctgtg ctgtttctgt
    22981 accagattcg ataacgtcag tatacaacgt tccttgtgct aggaaagaga cgccttcttc
    23041 accagcaagt tttgttgctt cgtcatcaaa aacatatacg aattcattcc caatgatttt
    23101 acgtttttgt tctgggtcag atacaccttt caacttgtct aagaagcgat ctcttgcatt
    23161 gactttgatg atgttcaagc cgaattttcc gcctagactt tccattactt gttccgcttc
    23221 gcctttgcgt agcagaccgt ggtcaacaaa gatagatgtc aattggtcac cgatcgcttt
    23281 ttgtaaaaga accccaacga cactagaatc aacgccacct gaaagaccaa gcaagacttt
    23341 tttgtcacca acttgttcac ggattttttc tacttgcata tcgataaagt tatccattgt
    23401 ccagttacct tcacagtgac aaacatcaaa ggcaaagtgg cgcagcaatt cgattccgta
    23461 ttcggaatga cgtacttctg catggaattg gataccataa aaattacgtg ttgtgtcttg
    23521 gatagaagca atcggacaat ctttgcttgt tccgactgtt tcaaagcctt caggaacttt
    23581 agttaccaag tcaccatggc tcatccatac tgtttgttgt tttggtgttt ctttaaacaa
    23641 gacagcttga tcgcttgtta cttctaacaa ggctttccca tattcgcggt ttttagcagg
    23701 ctctacggaa ccgccaagtt tgtacgtgat caattgcata ccatagcaaa tccctaatac
    23761 aggaatacct aaattgaaga tctcaggatc gatcccaaat gcattctcat catatacact
    23821 gtttggtccg ccagaaagaa tgattccctt tggattcatc gcttttactt cttctgcagt
    23881 aatgcggtgg ctcaataatt cggaaaagac tccaagatca cgaatacgtc ttgtgatcaa
    23941 ttggttatac tgactaccgt agtctaatac gataatcttt tcaacgttcg tcatatcggc
    24001 aacgtttgtc aaatttatta cccctatccc tttaaatttt atctcaaaat agtcaaacta
    24061 ttttaaaatg ctaatatttt cgcatgaaaa tcgaatcgat gatatgattt tcagttttat
    24121 ggagaattat atcggctctt cctcgtgtag gcaagatata ttcctgtaaa tttttcaaat
    24181 tcacattttt ccatacatct tttgccattt taaaggcttc ttcacgatct ccgatagcaa
    24241 aacgataata ataattctct ggattttgga aagccgtatc cagtaacgca ccaaaacgat
    24301 ccaaatacca tttttcgatc agcacgggat cggcatcgac atagacagaa aaatcaaaaa
    24361 agtcgctgac gtagatttgc tgattcgcag gtaattgaag cgtattgatc ccctcaacga
    24421 tcaagatatc aggctgctgg atcaattcgt acttgtctgg aatgatatca tacacatcat
    24481 gtgagtaaac aggtactttt atctcttcct gaccagattt tacacggttc aagaaatcga
    24541 tcagcatctc catatcataa ctttcaggaa atcctttacg gtccatgatt ccacgctctt
    24601 ttaatatacg atttggataa agaaatccgt cagtcgtgat cagctgaacg tttcttcgtt
    24661 tgaaggtacg agacaaaatc gtctgcagca gtctggctgt tgtacttttt ccaacggcta
    24721 cacttccggc gatcccgata ataaaaggcg gtacttctac gtatttatga agaaataaac
    24781 ctttactcaa gaacaaagat tcaaattctt tcatataaag ataaatcaga tgagcaagag
    24841 gtacatagat atctcgaaca tcctgcatgg aaatgcggtc attcaaactt ttgatattat
    24901 ctagttcatc ttgtgtcaaa ggtgcttgcc cattacgata aaattctcgc cattcttctc
    24961 ttgccacacg gtagtagttc attggatcat tcatattagc ctcctgcgtt ctcccatcaa
    25021 tggaactatt ttaacacaaa ataaacgcaa accccaccac ttaagagaga ttgccgatct
    25081 ttttgtataa tctttataat agaaagaaac ggagtcttat tcttgacttg cgcacggata
    25141 cataaaagga tagactgttg tcatgaaaga aatgagaagg atggaagaca tgacaaatca
    25201 ttactattct gaacgcccag atacggcgca cgattttgaa caatgggctt ttgagttaaa
    25261 aggcagaacc tttcaatttg taacagattc tggtgtattt tcacgtgaaa cagtggatta
    25321 tggttcacgt gtcctgattg atgctttcga ttgggaagag ttacctgatg aaggaaagat
    25381 cttagatgtg ggatgcgggt atggaccgat tgggttagct ttggcatttg cgacacagcg
    25441 gtttgttgaa atggtcgaca ttaatgaacg agcggtaagt ctagcgcaag gaaacgcaaa
    25501 gcgtaaccaa atcgaacatg ttgatatcca tcaatcgaat atctatgaag cagttcatga
    25561 agaaacctat gcagctatcg taagcaatcc gccgatccgt gctggaaaaa aagttgtaca
    25621 tgaaattttg acaggcgcat atcctcggtt gaagaagggc ggtacactga caattgtgat
    25681 ccagaagaaa caaggagcgc cgagtgcgca aaagaaaatg gaagaaacat ttggtaatgc
    25741 agaaatcgtc acaaaagata aaggatatta tatcatcaaa agtgtgaaag aataactagc
    25801 tgaaaaatag tggagcgacg aaagagtgga actgggcgtg catgtacggg tacgtatcag
    25861 ttcttttttt gttgagaagt ttttaaaaac aaagaactat tttttcttca aaaagaaata
    25921 gtaggaacag agtcgttgtt ttttacgata aaataaataa gatacagaac ttgtatagaa
    25981 ggctgccaag tcggtagata aaggaggttt ttatcaaaaa acatactttc cttttttctc
    26041 tattcttttc ttgggggttt tggtacactg atagggaatt tagatagaag ggagccaata
    26101 ggatgaagct gaccatcaga gatatcgcag aaatggcagg cgtatcagta acaactgtct
    26161 cacagatttt gaataacaaa ggaagcagat ttagtgataa gacaagaaaa aaagtgttgt
    26221 cgatcgtgaa tgaacatcat tataagcccg attatttcgc ttcaaatgtg atcaatcgac
    26281 attcaaagac catcggaatg atcgtccctg atgtcactga tttcttcttc tccaaactga
    26341 tcgaaggtgt agagagctat ttgaatcctt tgggctatgt gatcatgtta tgcaattctc
    26401 gtcatagcca agaaaatgag atcaagtatt tacaagagct ttcccaccgc tcagtggacg
    26461 gaatcttgct ggccacacca aatattttac ctgagaaata tgcattagac agcggttttt
    26521 atcaaaaaat gccaatcatt ttaatcgatc gcggattgaa tcgtcgggat aacggacggc
    26581 ttatcgtaaa ggaatatgag ggcgcctatc aagctgtttc gctgtttatt gaaaatggcc
    26641 atacgaagat cggcatgctg aaggaaacca ctggatacta tcaattagaa gaacgtttca
    26701 acggatatcg tcatgcgctg aaagatcatg gcctgccttt taatgggaaa tttgttgaac
    26761 atggagagtt gactgtccaa ggtggatata ctgcatcaaa aaaattactc aaacataaag
    26821 atatcacggc tattttttgc gggaatgatg ccatggcgat cggatgctat caggcgatcg
    26881 atgaattggg caaaaaaatc ccagaagata tctcagtcat aggattcgat ggattaaagc
    26941 tgtcagaata catgattccg caattgacga cagtgcagca gccaagtttt gatattggat
    27001 tttatgctgc acgtttcctg atcgatacga tcgaatttcc tcaaagaaaa gttccgaaca
    27061 aagtgttcga aacaaaatta attattcgtg agagcgtaaa agtattgaca aagggctaac
    27121 tcggcggtat attgcttatg taagcattta caaaggctag ttagtgcttt ttttattttt
    27181 agtaaaccag tttactaaag tggtttacct ttcctaaaaa taatgtataa taccgaatga
    27241 agacaaggag gatcaggcaa tgcgaatggt ggatctgatt gaaaaaaaga gggatggaaa
    27301 cgagctgtcg aaagaggaaa tcgagtacat cgtcacgaac tatacgaatg gaaagattcc
    27361 agattatcaa gtcagtgcat tattgatggc aattttttat caagacatga caaatgaaga
    27421 aatcacgaac ttaacattgg cgattgctaa ttctggtgat gtcatcgatt tgagttctct
    27481 tgaaggaata aaggtagata agcattcgac aggtggcgtt ggtgacacga ccacattgat
    27541 tttagccccc ctagtagcta gtgtcggagt gacagtggct aaaatgtctg gacgcggtct
    27601 aggttacaca ggtggtacac tagacaagct agaagcaatt cccggatttc agatcgagct
    27661 ttcggatgaa gaatttgtac gcattgttaa tgaaagtaaa gtagcggtaa ttggtcaatc
    27721 aggaaacttg gcaccggcgg acaaaaaatt gtatgccttg cgtgacgtca cagcgaccgt
    27781 tgattctctt ccgctgattg ccagttcgat tatgagtaaa aaaatcgcgg caggagcaga
    27841 tgcaatcgtt ttggatgtga ccactggaga cggtgctttc atgaagaaca tcgaagatgc
    27901 aagacgtctg gcaaagacca tgacgagcat tgggaaactg gctaaccgag aaacagtggc
    27961 ggttatctca gatatgtcag aacctcttgg cgaagctatc ggaaatagtc tagaagttgt
    28021 cgaggcaatc gaaacattac aaggaaatgg tccagaagat ctagtagaaa tgtgctacgc
    28081 cttaggaagc caaatggttg ttcttgctgg caaagctaag acaaccgatg aagcaagaac
    28141 gttgcttcaa gaagctctgg aatcaggtaa agcgttagca aaattcaaag aaatgatcca
    28201 aaatcaaggg ggagacccag cgatcgtgga acatccagaa cgaattttga ctgcacgcta
    28261 cacaatggag cttcctgcta aacaaagcgg agttgtgtca aaaatcgtgg caaatgaatt
    28321 aggaattgct gcaatgatgc taggtgctgg gcgtaaaacc aaagaagaag atattgatca
    28381 cgctgttgga ttgaaactgc ataaaaaaat tggtgacact gtgacaaaag gtgagtcact
    28441 attgacgatc tatagtaacg acgaagaaat cacttctgtc attgaattat tatataaaaa
    28501 tattgaaatt ggtgaatcgg caatgaagcc aacgttgatt catgacatca tcacagaata
    28561 aaggaaaaaa gcggacttta ccgttttaaa gaaaagggga aaagaaatgg aactaaaccg
    28621 aatgatcgac catactattt tgaaagcaga cgcatctaaa gaagctgtga tgcaaattat
    28681 cgaagaagca aaaaaatacc atttttattc tgtctgcatc aatccagcat gggttgcgct
    28741 agcgaaagaa caattacaag gtgagccagt agccgtatgt acagtaatcg ggtttcctct
    28801 aggagcaaac acacccgaga caaaagcatt tgaaacaaca gatgccatca ataacggtgc
    28861 agatgaagtc gatatggtca tcaatatcgg tgctttgaaa tcaaaggatg atcaacaagt
    28921 ccaaaaagat atcgaagcag ttgttgaagc agcaaaagat cgtgcgcttg tcaaagttat
    28981 tattgaaaca tcgttattag atagagaaga aatcatccga gcttgcgaaa tagcaaaagc
    29041 tgcaggcgct gattttgtca aaacatcaac tggtttctca acaggcggag caaaggtaga
    29101 ggatgtccgt ttgatgcgtg aaactgtagg accagaaatg ggtgtcaaag cttccggcgg
    29161 tatccataac gaagaagaag caatggcaat gatcgaagct ggtgctacaa gaatcggaac
    29221 aagcgcagga gtagcaatcg tatctggttc aactggtgaa ggctattaat tttttcaaag
    29281 gagaagctca tggcagaact caaacaagaa tggatcaaca cagctattga agcgttagat
    29341 aaagcctatg ttccttattc ccattttccg gtaggcgctt gtctcgtaac ggaatcaggc
    29401 aagatttatc aaggcatcaa cattgagaat gcatcatttg gattaacgaa ttgtgccgag
    29461 cgcacagctt ttttcaaagc agtatctgaa ggagaaaaaa catttacgca tctagtcgta
    29521 gcggggcaca cccccgatcc tatctctcct tgtggtgcat gtcgacaagt aatggcagaa
    29581 ttctgttccc ctgatatgcc ggttacgcta gtaggagaca atggtgtgac gaaggcaacg
    29641 accgttcgtg cactgctgcc ttatgcattt actgaaaaag atctataact catgttcatt
    29701 cagtcagctg actgttgaaa aataaaacaa ttattttagg aggctttaca gaaatgaaaa
    29761 aagcaaaatt atttggttta ggtgctgtcg cactagcagc agggttattt ttaggtgcat
    29821 gcggcaacaa cggctctact gattcatccg gtggcaaaag ctcatcagac acaacaactg
    29881 cagcattgat cacagacaca ggtggtgtag acgaccgttc attcaaccag tcagcttggg
    29941 aaggactaga aaaatggggg aaagatcaag gactttcacg aggaaatgat ggcttccaat
    30001 atttccaatc ttcaaatgaa tcagattaca tcccaaatat tgaccaagca ttgaatgctg
    30061 gattcaaaac gatttttggt attggttata aactaaaacc agcgatccaa gaacaagcaa
    30121 caaacaatac aggtacgaac tttgttatta tcgatgatgt catcgatgga ttagataacg
    30181 ttgtatctgc aactttcaaa gacaacgaag cttcttatct tgcaggtgtt gcagcagctt
    30241 atacgactga aacaaacgta gtcggcttta tcggcggtgt aaaaggtgaa gtaatcgatc
    30301 gttttgatgc tggattcaaa gccggtgttg atgcaggtgc gaaagaatta ggaaaagaaa
    30361 tcaaagtatt gaatcaatat gctggtgact tctctgctcc agataaagga cgttcaattg
    30421 ctcaaggtat gtatgcacaa aacgcagata tcatcttcca tgcttcaggc ggtacaggta
    30481 acggtgtatt ccaagaagca aaatcattga acgaatcagg cgacaaaaaa gtttgggtta
    30541 tcggtgttga ccgcgaccaa tcagacgaag gcgaatacac attaaacggc gaaaagaaaa
    30601 acttcacatt gacatctaca ctgaaagcag ttggaacagt agtagaagat ttggcacaaa
    30661 aatcagcgga cggtaaattc cctggcggcg aacacactgt ttatggattg aaagaagacg
    30721 gtgttggtct aacagaagga caactttctg acgaagcgaa aaaagcagtt gatgaagcaa
    30781 aagaaaaaat catttcaggt gacgtaaaag ttccagaaac tcctgaagaa aactaaaacc
    30841 atttctatag ccttgttaga cacatgtttg acaaggctat ggtttgatta gaacaagaat
    30901 tgttcattta tccaagctgc cttgtgacag tttggataag ggaacaactc cctgaagtaa
    30961 tgtttgtttc aaaagaagaa cgctcactaa gcgtgaatct tagtcaatcg ttgccctaga
    31021 tagaaatcgt taggatgtga aaaaaaggtg gttcaagaaa atattgtcat agaaatgcag
    31081 aatattacca aagaatttgg aacattcaag gcaaatgaca acatcaattt acaagtaaag
    31141 gcaggagaaa ttcatgcgtt gcttggagaa aacggtgctg gcaaatctac attgatgaac
    31201 gtgctttccg gattattaga gccgacatca gggaaaattt tgatgcgtgg gaaagaagta
    31261 aagatcacaa gtccgaccaa agccaaccaa ttagggattg ggatggtcca tcagcacttt
    31321 atgcttgttg atgcctttac tgtaacagaa aacatcgtgt tgggaagcga gcctagtcgc
    31381 gcagggatgc ttgaccataa aaaagcacga aaagagatcc aaaaagtttc tgaacagtat
    31441 ggattgtcag tcaacccaga tgcttacgtt cgtgatattt cagttggaat ggaacaacgg
    31501 gtagaaattt taaaaacact ttaccgagga gcagatgtac tgatttttga tgagccgaca
    31561 gctgtattga cccctcaaga aattgatgaa ttaatcgtga tcatgaagga attagtcaaa
    31621 gaaggcaagt cgatcatttt gattacgcat aagttagatg aaatcaaagc agtagctgac
    31681 cgctgtacag ttatccgccg tggaaaagga atcggtacag tcaacgttaa agacgtaacc
    31741 tcacaacaat tagccgatat gatggttgga agaacggttt cattcaaaac gatgaaaaaa
    31801 gaagcgaagc ctcaagaagt cgttttgtct attgaaaatc tagtggtgaa agaaaatcgt
    31861 ggattagaag ccgtgaaaaa cttgaactta gaggttcgtg ctggcgaagt acttggtatc
    31921 gctggaatcg atggaaacgg gcagtcggag ttgatccaag ctttgactgg tttgcgaaag
    31981 gcagaaagcg gacatatcaa gctaaaaggg gaagacatca ctaataaaaa accccgaaaa
    32041 atcactgaac atggtgtagg acacgtgcca gaagaccgtc ataaatacgg gttagtccta
    32101 gatatgacat tatctgaaaa tatcgcacta caaacctatc atcaaaaacc ttacagtaaa
    32161 aacggcatgc tgaattattc agtaatgaat gaacatgcca gagaattgat cgaagaatat
    32221 gatgttcgaa caacgaatga acttgttccc gcaaaagctt tatcaggcgg aaatcagcaa
    32281 aaagcaatta tcgctcgtga agtcgaccga gatcctgatc tgttgattgt tgcaaatcca
    32341 actcgtggac tggatgtagg tgcgatcgaa tttattcata aacgtctgat cgaacaaagg
    32401 gacaaataca aagcagtgtt actgatcagt ttcgaattag aagaaatttt aaatgtttcg
    32461 gatcgtattg ctgttatcca tgaaggagaa attgtcggta tcgttgatcc gaaagaaaca
    32521 tctgaaaatg aattaggtct attgatggcg ggctatacct tagaagaagc acgaaaagag
    32581 ttagaaaagg gggctggcgc acatgaatga tcgcagcgaa aaattccgta atttattagt
    32641 gcctgtactt tcagttgttt taggattgat cttaggcgcg atattgatgg ctgcttttgg
    32701 ttttcagccc atccaaggtt attcttctat gctagatgca gcccttggtt cgcaaagagg
    32761 gataggtgaa acgttaaggc aagcaacgcc gttgattttt acagcattag gtttttctgt
    32821 agctaactca gctgggtttt tcaatattgg gctttctgga caagcacttt gcgggtggat
    32881 cgtcagtgtc tgggtggcac ttgcgtttcc agatctgcca aaagttgttt tgcttccgtt
    32941 atgcgtgatc ttaggtgcct tagctggtgc gatggcagcg gctgttccag gtttacttcg
    33001 agcatttttt ggaacaagtg aagtgatcgt aacaatcatg atgaactata tcttattata
    33061 cgtaagcaca tttgctttac atgaagtgat gcctgaaagc tatcgctcaa gtttggactc
    33121 ttccaatatg atcagtcaaa atgcctcact gcggttacca tggttaacac aagcttttgg
    33181 cggctctcgc gtaaactcag gattattttt agcaatcatc gcgcttattt tcgtttggct
    33241 gctgatgaag aaaacgactt taggatttga aatccgttct gttggattga atccttttgc
    33301 ttctgagtat gcaggaatga gtagtaaacg tacgatcgtt ttgtcgatgg tcatttctgg
    33361 cgctttggca gggcttggcg gtgtggttga aggattagga acgtatcaaa acttctttgt
    33421 tcaaacgact tcgctatcta ttggatttga cggaatggct gtttccttgc ttggttctgg
    33481 atcagcaatc ggtattcttt tatcagcgat cttgttcagt attttgaaga tcggtggact
    33541 tggcatgcag acaggagcag gtgttccgtt tgagatcgtc aatgtatcga ttgctttgat
    33601 tatcttcttt gtcgggatca acttcctgat tcgtttcgtc atggctaaag tcttccaagg
    33661 gaaaaaacaa gaagagatcg ttgcgacaat agaatcgaaa ccaacgaatc aaaaccatga
    33721 agggggcgaa ctataatgtc gactatcgaa ttaattgcct tgatccttac ttctacactg
    33781 gtttattcaa caccgctaat tctaacgtca ctaggcggaa ctttttctga acgaagcggg
    33841 atcgtaaacg tagggctaga gggaatcatg gtcatgggtg cttttagttc catcgttttc
    33901 aacttgacga tgagtccatc acttggttct atgacaccat ggatcgctat tttagtgggt
    33961 ggcgtcgtag gtatcctatt ttctctgatt cacgcagtag caacagtcag tttgcgtgct
    34021 gaccatatta tcagcgggac agtaattaat ctgatggcac ctgctttagg tgttttcttg
    34081 atcaaagcat ggtatggtaa aggtcaaact gataacatca cgcagaatct ggggtatttt
    34141 tctttcccag gattagcaga tattccggtc attggaccaa ttttctttaa aaatacattc
    34201 ttacctgctt attgtgctat tttgattgct gtcctagctt gggtgatcat cttcaagacg
    34261 aaattcggct tgcgcctccg ttcagttggt gaaaatcctc aagctgccga cacattaggt
    34321 atcaatgtat atgctatgcg ttattcaggc gtactgattt ctggcttgtt aggcggtatg
    34381 ggcggtgctg tttttgctca gtcgatttcc ggtaactttt cagctggtac gatcgttgga
    34441 caagggttca tctccatggc tgctatgatc tttggtaagt ggaatccttt aggggcaatg
    34501 ggtgcctcat tgttctttgg ttttgctcaa agcttgagta tcattggcgc acaattacca
    34561 gttatttctt cgattccgcc agtattgctg caaattgctc catatttgct gacaatcatt
    34621 gtgctggttg ttttcttagg gaaagcttct ggtccaaaag caaacgggaa gaactatatc
    34681 aaatcaaaat aatcttttag cgaataaaaa gggtgggtta cgggaagtgt ttttcgtctc
    34741 gccctttttg ttttaaaggc aataaaaata aaaagaaaga aggaataatc atgtttaaac
    34801 gcgtacatct gatcgtcatg gattcagtag gaattggaga agcaccagat gccgataagt
    34861 tcggtgatgt tggttctgat acattaggac acattgcgaa agaagcagga ttgaacgttc
    34921 cacatttaga gcagcttggt ttaggaacga tccgtcctct tgaaggtgtg gaatcagtga
    34981 aagatcatca aggctatgcg acgaaattag aagaagtttc tgtagggaaa gatacgatga
    35041 caggccactg ggaaatcatg ggattgaata tcaaaactcc atttcgtgtg tttcctaatg
    35101 gattccctga tgatctgatc aaacaaatcg aagaattttc tggccgtaaa gtcgtatgta
    35161 acaaacctta tagcggaaca gctgttattg acgattacgg tgaacaccaa atgaaaacag
    35221 gcgatttaat tgtatatact tctgccgatc ctgtccttca gatcgcggca catgaagaaa
    35281 tcattccttt agaagaatta tatcggattt gccaattcgt tcgtgatata acaaaagatg
    35341 atccgtatat gattggccga atcattgcac gtccgtacgt gggtgaacca ggagacttca
    35401 cacgaacaag caatcgccat gattatgcgt tgaatccatt cggacacaca gtccttgatt
    35461 ctttgaaaga agcaggaaag gacgtgattg ctgttggaaa gatcaacgat attttcaacg
    35521 gacaaggaat cactgaatct gtccgcacga aaagcaatat ggatggcgtt gaccagctgc
    35581 tgaaagttat gaaaaacgat ttttcaggaa tcagctttac caatttagta gattttgatg
    35641 cattatacgg tcatcgtcgg gatgtagtcg gctatgcgca tgcgattgaa gaatttgact
    35701 tacgaattcc agaattgctt gaagcgatgg aagaagacga cttgctaatg attacagccg
    35761 atcacggaaa cgatccgacg tttactggta ccgatcatac gcgagaatat gtaccgttat
    35821 tggtttacag taaaaaaatg aaagaacaag gggcattgcc tcaaggatat tattcagata
    35881 tttcagcaac gattgctgag aactttagtg tttcttcgac tgaaaatggc gaaagcttct
    35941 tgaaattatt aaaataatct ttttaaatag gagaaagcaa atgaccaagt taagcgagat
    36001 gttacaagaa acgacccagt ttatccttga taaaggagta aaagaaattg attttggttt
    36061 gattctaggt tcaggattag gtgaattagc agatgaaatc gaagatgctg taatgatttc
    36121 ttatgatgag atcccgttct ttcctgtttc gacagtagtt gggcatgcag gaaagctagt
    36181 ttatgggtct ctggcaggca agaaagtgtt agccatgcaa gggagattcc actactatga
    36241 aggtcattcc atgcaaacag tgacctatcc agtacgtgtg atggccggac taggggccca
    36301 ttcagtcatt gtgactaatg catgtggtgg tgtcaacgaa tcatttgtac caggagattt
    36361 gatgctgatt accgatcata tcaattttac tggtgaaaat cctttgatcg gtccgaatga
    36421 agatgcaatg ggccctagat ttccagatat gagtcaagct tatacgcctg actatcaagc
    36481 aacagcaaaa gcagcagcag aaaaactagg tttggatctt aaagaaggcg tatatatggg
    36541 ctattctgga ccaacttatg aaacgcctgc ggagatccga atgtctcgga caataggagc
    36601 cgatgcagta gggatgtcga ctgttccaga agtcatcgta gcagctcaca gcggattaaa
    36661 agtgttagga atctcttgta ttaccaactt agcagcaggt atgcaagcga atctgagcca
    36721 tgaagaagtt gtagaaacaa ctcagagagt caaacaatct tttaaagcat tggttaaaga
    36781 aacattgaca ttattgtaat aggaggaaca ataaaatgag tgtgcatatt gaagcgaaag
    36841 aaggcgagat cgccgataag attttacttc cgggagatcc tttgcgagct aaatatattg
    36901 cggagacttt tttggaagat ccagtttgtt acaatcaggt acgcggtatg ttaggcttta
    36961 ccggcaaata taaaggagaa cgtatttctg ttcaaggaac aggaatggga atgccatcag
    37021 ccaccatcta tgcccatgaa ttgatccagt cgtatggtgt aaagaaattg attcgagtag
    37081 gtacatgcgg tgcattgtca aaagacgtcc atgttcgtga tttagtacta gcacaaggtg
    37141 cagcgaccag ttcttcgatg atcgaaaaaa atttccaagc ctttcatttt cctccaatca
    37201 gtgatttcaa tctattactg aaagcatatg agatagctaa agaaaagggc tatacggttc
    37261 atgtaggaaa tgttctttcg gaagattctt tctacaaaga tgatttgaca gagacgttcc
    37321 aattagctga acttggcgtt ttaggagtgg aaatggaagc agcggctctt tattacttag
    37381 gcgcgaaata ccatgtgcag acattaagtt tgatgaccgt tagcgaccat ttgatcaccg
    37441 gtgaagaaac aacagctgca gaacgtcaat ctacgttcaa tgaaatgatc gaagtaggat
    37501 tggaaacagc gatagcagaa taagaaggaa atgaaaaagc tgccctgcat taagtaataa
    37561 gaacatccaa gcaaaaatag ctcctcatgt ttttgacttg gctggactta ttattgcaaa
    37621 tgtaagcttt tgaacaccgt ttaccaagag gttgtgaatc tgccgtttaa ctctgagtca
    37681 caaggaacaa tttcaaaaaa cagcttttca tgtttgatga atattgtgac ttgtgaccga
    37741 gaagttggca ggagaaaacc gtttatacga aaaaagggac tgtgacaaat cgtgtcacag
    37801 tccctttttt atagtgtttt ttataggtag tattttttag caactgttaa gtcatcattt
    37861 aattcataaa caagtggttg acctgttgga atttcaagat ccatgatgtc ttcgtcagag
    37921 ataccttcga tatgtttagc tagggcgcgt aatgagttac catgtgcagc tactaaaaca
    37981 gttttgttgt ctagtaatgc tggagcaatt tcatcttgcc agaatggcaa agcgcgttct
    38041 aatgtcactt tcaagttttc tccaccagga atatcgcgtt tgtctaacat tgcgtaacga
    38101 cggtcatttg ctgcagaacc ttcgtcagtt tcttccatta atggaggaag agtatcgtaa
    38161 gaacgacgcc agatgtgcac ttgttcgtcg ccgtattttt cagctgtttc ttttttgttc
    38221 aaaccttgta atttaccata gtgacgttcg tttaagcgcc atgatttgat ttgtggtacc
    38281 caaagttgat ctgaatattc taagatcaag ttacatgttt tgattgcacg agttaaaaca
    38341 gaagtgtaag caacatcaaa ttcgattcca gcttctttga ttttgcgtcc gccttctttt
    38401 gcttcttcga ttccttctgg tgctagattt acatcagccc aaccagtaaa ttggttcaat
    38461 gcattccatt cactaagacc gtgacgagaa aaaactaatt ttggcatgtt tagctctcct
    38521 tttaagatag gtttatattt ctgaaatttt cagttctgtt ttattgtaca attttttgga
    38581 agagatttcc atcgaaaaat tagataagat tctatgagaa aacaagtaga gaatataaaa
    38641 aaacgaacag tgcccacgca actgttcgtt tttaggtatt agatgcataa ttgctcgatt
    38701 tctttttcag gtaaattgat atatttataa catgttccaa ctgaaacacc gcattttgaa
    38761 gaaataaatt ggatcgtttc ttttttttca taatagagac gtcggatttt tttgatcgtt
    38821 tttgcatcga tttttggtct tccgccgatt tttccttttt tacgagcttc atctaatcca
    38881 actaatgtac gttctttgat caatgcgcac tccatgtttg ctaggttttc cattaattgg
    38941 aaatagattt ttcccatttc gcgcgtatcg attccttcat caagactaat caagtgcagc
    39001 ccgcgatctt tgaataattg cgtgagttct gttaattgcc gcgtagattt gcctaatcga
    39061 tgaagttggc aaatgactag tgcatcgcct tgttgcatgt cagcgatcac tgactccaaa
    39121 tgaacagcag tagaatcatt ttgttccact tcatatgtct catggaaaat ttcttgacaa
    39181 ccaaagtcag ataattgatc aacctgagtt gttaaatcaa cgtcatttat ggttgtgcgt
    39241 gcataaccaa taattttcat ggtgattcct ttctagcagt gattttctaa ctggatataa
    39301 cagtaaaaat gtagcataaa gtacgtcaaa aagatagttt tttcgcaaat tttccgctgt
    39361 ctttttttat tggatgatca agcagttttt ctttatttac gacggattgc gtcaagaatc
    39421 tcaacgcctt tttctgagcc gacaactact ttagaaacca tgtttaggaa aagcccatgt
    39481 tctactaccc caacaagttc atctaaatag gtagctaagc tttctggctg ttcgatgact
    39541 tctagatgca gatcaatgat gtaatgacca ccatctgtgg ttaagacttc tccgttttcg
    39601 tctgtacgca agacgggttg gaatcttttt tcttcaaaaa tatgaagtag ctgttgggag
    39661 ccataaggga tcacttcaac tgggagtggg aacttcccaa gtttatcgac taatttagaa
    39721 gaatcaacga tccaaatcgt ttcttttgag tacgtagcga ctattttctc gaaaagcaaa
    39781 gcagcgccgc cgcctttgat cccttgaaaa tcagcactga tttcatcagc accgtctatt
    39841 gtcaaatcga ctacggggac ttcatcaata ctctttaacg gtattcctaa tttttccgct
    39901 tgttcttttg tcgcatttga agtagtaact cctgtgatac gtaaaccttc ttcacgcata
    39961 cggcgaccaa tctcttctac catataatag gcggttgaac cggtcccgag acctacgatc
    40021 atcccgtcct ttacgaattt cgcggcttca atgccagcta attgttttaa attcatcttt
    40081 gcgtccacct ttttttagtt tgagcatcgt gctttcctca ctattttagc gtgatttacg
    40141 gtaaaaagat accattcttt tttattccaa taaagctttt tcaaaaaaaa ttgcatctct
    40201 tgttgacatg ttttttcatt cgtgatattc taacaaaggt gctttatcta caggtttctg
    40261 tgaagaaacg tgctgactgt ttatcaaagc atatttgata aggatgcaga cattgcattt
    40321 attttttatc acaaaaaaag aaccacctgg atgtgtggaa ctagacgcaa atcgtgggaa
    40381 ggaggaaaca aggaatgcct acaattaacc aattagtacg taaacctcgt aaatcaaagg
    40441 tggaaaaatc taattcacct gctttgaaca aaggatataa cagctttaag aaaactcaaa
    40501 ctaacgtaaa ctcacctcaa aaacgtgggg tagcaactcg tgtgggtaca atgacaccta
    40561 aaaaaccgaa ctcagcttta cgtaaatatg cacgtgttcg tttgtcaaac ttaattgaag
    40621 ttactgctta tatcccaggg attggtcata acttacaaga acacagtgtt gtattattac
    40681 gcggtggtcg tgtaaaagac ttaccagggg tacgttacca tatcgttcgc ggtgctttag
    40741 atactgctgg tgttaacgac cgtaaacaaa gccgttctaa atacggaact aaaaaaccta
    40801 aagcttaatt ttaattatta aacaaatgaa acttgcttct actatataga agtaattact
    40861 atgaacaata tttcggaagg aggagttacg gatgccacgt aaaggtcctg ttgcaaaacg
    40921 tgatgtttta ccagatccta tttataactc aaaattagta actcgcttga tcaaccgtgt
    40981 aatggttgac ggaaaacgcg ggattgcagc taacattatc tataatgcct ttgacttgat
    41041 caaagaatct acaggtaacg atccattaga agtgtttgaa caagcaatga aaaacgttca
    41101 acctgttctt gaagttaaag cacgtcgtgt tgggggttca aactaccaag taccagttga
    41161 agttcgccct gaacgccgcg ttactctagg tcttcgttgg gtagtaaact acgctcgctt
    41221 gcgcggtgaa cacacaatgg aagaacgctt agcaaaagaa atcatggatg ctgcaaacaa
    41281 cacaggtgct tctgttaaaa aacgtgaaga cactcataaa atggctgatg ccaaccgtgc
    41341 gtttgctcac tatcgctggt aagattctct ctgtttggtc ggcttttata agtcgacctc
    41401 agatagtgtc cttattttta gcaactagat agtaaagaga ggagaaacaa ggagaatgac
    41461 cagagaattt tctttacaaa acactcgtaa tatcggtatc atggcccaca tcgatgctgg
    41521 taaaacgact gctactgaac gtatcttgta ctatactggt aaaatccata aaattggtga
    41581 aactcatgaa ggagcttcac aaatggactg gatggaacaa gaacaagaac gtggtattac
    41641 gatcacttct gctgctacta cagcacaatg gaagggtcac cgaatcaaca tcatcgacac
    41701 accaggacac gtagacttca cagttgaagt tgaacgttca ttgcgtgtac ttgatggtgc
    41761 tgtaactgtt cttgatgcac aatcaggtgt tgaacctcaa actgaaacag tttggcgtca
    41821 agcaacaact tatggtgtac ctcgtatcgt atttgcaaac aaaatggaca agatcggtgc
    41881 tgacttctta tattcagtat caactttaca tgaccgtttg caagcaaacg ctcacccaat
    41941 ccaattacca attggtgcgg aagacgactt cacaggaatt atcgaccttg taacaatgaa
    42001 ggctgaaatg tatacaaacg atcttggaac agagatcgaa gaaacagaaa ttcctgaaga
    42061 ataccgcgaa ttagctgaag aatggcgcga aaaattggtt gaagctgtag ctgaaactga
    42121 tgaagaactt actttgaaat acttagaagg tgaagaaatc actgaagctg agttaaaaga
    42181 aggtatccgc cgcgcaacag ttaacgtaga attctaccca gtactatgtg gttcagcatt
    42241 taagaacaaa ggggttcaat tactattgga cgctgttctt gattacttgc catcaccgtt
    42301 agatatccca gctatcaaag ggattgaccc taaaactgat gaagaagtag aacgtcctgc
    42361 agacgacagc gctcctttct cagctttagc atttaaagtt atgactgacc cattcgtagg
    42421 tcgtttaact ttcttccgtg tgtactctgg tgttttacaa tcaggttcat acgtacaaaa
    42481 cgcaacaaaa ggcaaacgtg aacgtgttgg tcgtatccta cagatgcatg ccaactctcg
    42541 ttcagaaatc tctgaagttt acgctggaga tatcgctgct gctgttggtt tgaaagacac
    42601 aactactggg gacacactat gtgatgaaaa gagtctagtt attcttgaat ccatggaatt
    42661 cccagaacca gttatccaag tcgctattga acctaaatca aaagctgacc aagataaaat
    42721 gggtgtggct ttacaaaaac tatctgaaga agatcctact ttccgtgctg aaacaaacgt
    42781 ggaaacaggc gaaacaatca tcgctggtat gggtgaactt cacttagata tcatcgttga
    42841 ccgtatgcgt cgtgaattca aagttgaagc taacgtaggt gcgcctcaag tatcttaccg
    42901 tgaaactttc cgtgctggca ctcaagccga aggtaagttt gtacgtcagt ctggtggtaa
    42961 aggtcaatac ggtcacgtat ggattgaatt tacaccaaat gaagaaggtg ctggtttcga
    43021 atttgaaaat gcgatcgtcg gtggggttgt tcctcgtgaa tacattccag ctgttgaaac
    43081 tggtttgaaa gatgctatgg aaaatggtgt cttagctggc tatccattag tagatatcaa
    43141 agctaaactt tacgatggtt cataccatga tgtcgattca aatgaaactg ccttccgtgt
    43201 tgctgcttct atggcattac gtgcagcagc taagaaagct aatccagtaa tccttgaacc
    43261 aatcatggct gtagaagttg ttatccctga agattattta ggtgatgtta tgggtcacgt
    43321 aactgctcgt cgtggacgtg ttgaaggtat ggaagctcgc gctggcggcc aacaagttgt
    43381 tcgtgcgatg gttccacttg ctgaaatgtt tggttatgct acaactcttc gttctgctac
    43441 tcaaggtcgt ggtacattta caatgacatt tgaccactac gaagatgtac caaaatcagt
    43501 acaagaagaa atcattaaga aaaacggcgg aaaagctgaa taatttcttg aaaccggata
    43561 gtcctgcaaa gagattatcc aaagagacta tatttttaat atagtttcgt gtaaaataat
    43621 tatcgatgat atgggcatgt ggtgtacctt gtgtacatca tatacctatc agacaaataa
    43681 aaaatatatt gtatttttag gaggacattt taaaatggca aaagaaaaat ttgaccgttc
    43741 taaaccacac gttaacattg gtactatcgg acacgttgac catggtaaaa ctacattaac
    43801 agctgcaatc acaactgtac tatctaagaa aaacggcggc caagctatgg cttacgatca
    43861 aatcgatggt gctccagaag aacgcgaacg cggaatcaca atctcaacag ctcacgttga
    43921 gtatgaaaca gatacacgcc actacgctca cgttgactgc ccaggacacg cggattacgt
    43981 taaaaacatg atcactggtg ctgctcaaat ggacggagct atcttggtag tttctgctgc
    44041 tgacggccca atgcctcaaa ctcgtgaaca catcctattg tctcgtcaag ttggtgttcc
    44101 ttacatcgtt gtattcttga acaaagtaga catggttgat gacgaagaat tactagaatt
    44161 agttgaaatg gaagttcgtg acctattaac agaatacgaa ttccctggtg acgatgttcc
    44221 tgtagttgct ggatcagctt tgaaagctct agaaggcgac gcttcatacg aagaaaaaat
    44281 tcttgaatta atggctgcag ttgacgaata catcccaact ccagaacgtg acaacgacaa
    44341 accattcatg atgccagttg aagacgtgtt ctcaattact ggacgtggta ctgttgctac
    44401 aggtcgtgtt gaacgtggac aagttcgcgt tggtgacgaa gttgaagttg ttggtattgc
    44461 tgaagaaact tcaaaaacaa cagttactgg tgttgaaatg ttccgtaaat tgttagacta
    44521 cgctgaagct ggagacaaca ttggtgcttt actacgtggt gttgcacgtg aagacatcca
    44581 acgtggacaa gttttagcta aaccaggtac aatcacacct catacaaaat tctctgcaga
    44641 agtatacgtg ttgacaaaag aagaaggtgg acgtcatact ccattcttca ctaactaccg
    44701 tccacaattc tacttccgta caactgacgt aacaggtgtt gttgaattac cagaaggaac
    44761 tgaaatggtt atgcctggcg acaacgtaac aatggaagtt gaattaatcc acccaatcgc
    44821 tatcgaaaac ggtactaaat tctcaatccg tgaaggcgga cgtacagttg gtgccggtgt
    44881 cgttacagaa atcaaagctt aattcactta agttttaaag taaagcaaca tttattcgga
    44941 cgtaatcgct cggaacgaag gtcttaggat ctttgttccg agctttttta tttattgcag
    45001 gatcaggaaa aaagacagga gtattataaa tagaagaaac acgaaataaa agagtcagta
    45061 ttttctaaat gaaactttat gaaaacaaaa tgttttttac aagaaaaagc cttgctttgt
    45121 gagtttatat atattataat gacaaaggtg cgtttacttt agtgaattgc acagacgtaa
    45181 tcagaatgat ttcgtcggct aagaaacgag aggttgcgac acgcccggac gctttgccac
    45241 gaacgagcgt gacggaaatt ttcgtggagc tatgtctact tttcaaaata ggcgaaggag
    45301 ggaacaagat ggcaaaacaa aaaattcgta tccgtttaaa agcgtatgaa caccgtattt
    45361 tagatcaatc agcggataaa atcgtggaaa ctgcaaaaag aactggagct agcgtgtctg
    45421 gtccaattcc attaccaact gaacgcagtc tttacacaat catccgtgcg actcataaat
    45481 acaaagattc acgcgaacaa ttcgaaatgc gtacacacaa acgtcttatc gacattgtga
    45541 acccaacacc aaaaactgtt gatgctttga tgaagctaga cttaccatct ggtgtaaaca
    45601 tcgaaatcaa attataaaac taaaacaaaa ataatggagg tgtactcatg accaaaggaa
    45661 tcttagggaa aaaagtggga atgacacaaa tcttcactga atctggtgaa ttaattccag
    45721 taactgttgt agaagctact ccaaacgtag tactacaagt gaaaacaatg gaaacggatg
    45781 gctacgaagc tattcaagtt ggttaccaag atatgcgtga agttttatca aacaaacctg
    45841 cgaaaggtca tgttgcaaaa gcaaacacgg ctcctaagcg cttcattcgt gaattcaaaa
    45901 atgttgagct aggagaatat gaagtaggaa aagaaattac agtagatgtt ttccaagcag
    45961 gagacattat tgatgtaaca ggtactacga aaggtaaagg attccaaggg gttatcaaac
    46021 gccacggaca aagccgcgga ccaatggctc acggttctcg ttaccatcgt cgtcctgggt
    46081 caatgggtcc agttgcacct aaccgtgtat ttaaaaacaa acgtcttgct ggccgtatgg
    46141 gtggcaaccg cgtaactatc caaaacttgg aagttgtacg tgtcgatgca gaaagaaatg
    46201 ttatcttgat caaaggtaat gttcctggag ctaaaaaatc tttaattact atcaaatcag
    46261 ctgtgaaagc taaataattg taggaagaaa ggaggaacta aggaatgccg aatgtagcat
    46321 tattcaaaca agatggaagc caaaacggtg aaatcacact taacgaagaa atcttcggaa
    46381 ttgaacctaa tgaaagtgtt gtttacgatg caatcgtaat gcaacgtgcg tcattaagac
    46441 aaggaacaca cgcggttaaa aaccgtagcg ctgttcgcgg cggcggacgt aaaccatggc
    46501 gtcaaaaagg aacaggtcgt gcacgtcaag gatctatccg ctcaccacaa tggcgtggag
    46561 gtggcgtagt ctttggacca acaccacgtt cttacagcta caaacttcct aaaaaagttc
    46621 gtcgtttagc aatgaaatct gtattgtcag aaaaagttgc tgaaaacaac ttggtagcaa
    46681 tcgaaggctt gaacttcgac gcaccaaaaa caaaagaatt caaacaagtt cttgctaact
    46741 tatctatcga ctctaaagta ttggttgttc tagaaaaagg taacgacttt gctgctttat
    46801 cagcacgtaa cttaccaaac gtttctgtag taacttctga taatgtgagt gtgctagacg
    46861 ttgtatcaaa tacaaaagtg ttagcaacac aaactgctct tactcaaatt gaggaggtgc
    46921 ttgcataatg aacttactag acgtaatcaa acgcccagtg atcactgaaa aatcaatgct
    46981 tgccatggat gacaagaaat acacttttga agtggacact cgcgcaaaca aaactttagt
    47041 aaaacaagcg gtagaagctg cttttgacgt taaagtcaaa aacgtgaaca tcgtgaacgt
    47101 acgtgcgaaa ttcaaacgta tgggcaaata tgcaggatat acaaaaaaac gtcgcaaagc
    47161 gatcgttaca ttgactgaag attcaaaaga aatccaatta ttcgaagctg ctgaataagc
    47221 actaatagat aactcattaa attaggaggg aaaaacgtgg cgattaaaaa gtacaaacct
    47281 acctcaaatg gtcgtcgtaa catgacaggt tctgattttg ctgaaatcac aacatcaaca
    47341 cctgaaaaat cattgttaca accattgaaa aaccatgctg gacgtaacaa caacggccgc
    47401 atcactgtac gtcatcaagg tggcggacac aaacgccaat atcgcgtgat cgacttcaaa
    47461 cgtaacaaag ataacgttgt tgcaactgtt caaacgatcg aatatgatcc aaaccgttca
    47521 gctaacatcg cgttagtaca ctatgaagat ggagtgaaag cttacatctt agcacctaaa
    47581 ggactagaag tgggtatgaa acttgtttca ggtccagaag cagatatcaa agtcggaaat
    47641 gctcttccat tagaaaacat tccagttggt actgttatcc acaacattga aatgaaacct
    47701 ggtaaaggtg gacaattgat ccgttctgct ggtacaagtg ctcaagtact tggtaaagaa
    47761 ggcaaatacg tattgatccg cttgaactct ggtgaagttc gtatgatctt agctgcatgc
    47821 cgtgctacaa tcggttctgt aggtaacgaa caacacgaat taatcaacat cggtaaagct
    47881 ggacgctctc gttggatgcg taaacgccca actgtacgtg gtagcgtaat gaaccctaat
    47941 gatcacccac acggtggtgg tgaaggtaaa gctcctatcg gacgtaaagc accagtttct
    48001 ccttggggtc aaccagctct tggttacaaa actcgtaaca aaaaagctaa atcagacaaa
    48061 cttattgttc gtcgtcgcaa aaataaataa ttactttgac catgtgtcgc acattttgag
    48121 aggaggttca ccatgggtcg tagtttaaag aaaggacctt ttgtcgatga gcatttaatg
    48181 aaaaaagttg aagctcaagc aggggttgaa aagaaaaaag ttatcaaaac ttggtcacgc
    48241 cgttcaacag ttttcccaag ttttgttgga tataccatcg cagtttatga tggacgtaaa
    48301 catgtaccag tttacatcca agaagacatg gtaggacaca aattaggtga atttgcacct
    48361 acaagaactt atcgtggaca tgctgctgac gataagaaaa cgaaacgcta atttgagggg
    48421 aggataaatc caaatggcag aacaaatcac atcagctaaa gcaactgcaa aaacagttcg
    48481 cacttcacct cgaaaagccc gtttagtaat tgaccttatc agaggtaaaa gtgtcgcaga
    48541 tgcaatttca atcttgaaat tcacaccaaa caaatctgct ggaatcattg aaaaagtatt
    48601 gatgtcagca gttgcgaatg cagaaaataa ctttgactta gatgttgaaa acttggtagt
    48661 aagcgaagct tttgttaacg aaggacctac aatgaaacgt ttccgtcctc gtgcaaaagg
    48721 atcagcttct ccaatcaaca aacgtacaag tcatatcacg gtagtcgtat cagaaaaata
    48781 aggagggata atcagtgggt caaaaagtac atccaattgg aatgcgtgta ggcatcatcc
    48841 gcgactggga tgctaaatgg tatgctgaaa aagagtatgc tgagttctta cacgaagatt
    48901 taagaatccg taaatttatt tcaactaaac ttgctgatgc tgctgtatca acagttgaaa
    48961 tcgaacgcgc aacaggtcgc gtaaacattt caattcacac agctaaacca ggtatggtta
    49021 ttggtaaagg cggttctgaa gtcgaaagcc taagaaaaga attaaacaaa ttaactggta
    49081 aaagaatcca tatcaatatc gtggaaatca aaaaaccaga tctagatgca aaattagtag
    49141 gtgaaggaat cgcacgtcaa ttagaaaacc gtgttgcttt ccgtcgcgct caaaaacaag
    49201 ccatccaacg ctcaatgcgt gctggcgctc aagggatcaa aactcaagta tctggtcgtc
    49261 taaacggagc agatatcgct cgttcagaag gatactcaga aggaactgtt cctcttcata
    49321 ctttacgtgc ggacattgat tacgcatggg aagaagcaga tacaacatac ggaaaactag
    49381 gagttaaagt gtggatctat cgtggagaaa ttcttccaac taaaaaaaac actgagaaag
    49441 gagggaaata atcatgttag tacctaaacg tgtaaaacac cgtcgtgaat tccgcggaaa
    49501 aatgcgcggg gaagctaaag gcggaaaaga agtagcattc ggtgaatacg gtttgcaagc
    49561 tgttgattca cattggatca caaaccgcca aatcgaagct gctcgtatcg caatgactcg
    49621 ttacatgaaa cgtggtggga aagtatggat taaaattttc cctcacaaat cttatactgc
    49681 caaagcaatt ggggtacgta tgggttctgg taaaggggca cctgaaggat gggttgcacc
    49741 agtaaaacgt ggtaaaatca tgtttgaaat cgcaggcgtt cctgaagaag tagctcgtga
    49801 agcgttacgt ctagcttctc acaaattacc aatgaaaact aagatcgtaa aacgtgagga
    49861 aatgggtggt gaatcgaatg aaggttaaag aaatcagaga attaaccact gccgaaatgc
    49921 ttgatcaaga aaaacaatta aaagaagaat tgtttaatct tagattccaa ttagcaacag
    49981 gtcaattaga aaacactgca cgtattaaag aagtacgtaa atcgattgca cgcatcaaaa
    50041 ctgtgttgcg tgaacaagct aagtaattat ggaaggaggc cattaagcgt atgactgaag
    50101 gaagaaatca acgcaaagtt tatcaaggtc gcgtggtttc agacaaaatg gataaaacaa
    50161 ttaccgttgc tgtcgaaaca aagaaaaacc accctatcta tggcaaacgc atgaactatt
    50221 ctaagaaata caaagtgcat gatgaaaaca acacagcaaa agttggcgac atcgtgagaa
    50281 ttatggaaac tcgtccatta tcagctacaa aacgtttccg tttgttggaa gtagtcgaag
    50341 aagcagttat tatctaataa cacgagattt tcctatatag attgaatgca aaatctgaaa
    50401 ggaggataca caacgtgatc caagcagaaa gtcgtttaaa agtcgctgat aactcaggcg
    50461 cacgtgaaat tttgacgatc aaagtccttg gtggatctgg tcgtaaaact gctaacatcg
    50521 gtgatgtgat cgttgctacg gttaaacaag caacgccagg tggggttgtc aaaaaaggtg
    50581 acgtcgttaa agccgttatc gttcgaacaa aatcaggagc tcgtcgtaca gacggttcat
    50641 atattaaatt tgatgaaaat gctgcagtga ttattcgtga tgataaaagc cctcgtggaa
    50701 cacgtatctt tgggccagtt gcacgtgaac tacgtgaaaa caacttcatg aagatcgttt
    50761 cactagcacc agaagtttta taatcttgag acacttatca aaggaggtgc gaaacagtta
    50821 tgtttgttaa aaaaggcgat aaagttaaag ttatcactgg aaaagacaaa aacaaagaag
    50881 gcgttgtact agcagcgttc ccgaaaaaag ataaagttat tgtcgaaggt gtaaatgtcg
    50941 ttaaaaaaca ccaaaaacct tctcaagctg ctcctcaagg tggaattgtt gagatggaag
    51001 cgccaattca tgtttctaac gtgatggtgg ttgactctac tggtgtagct ggccgagttg
    51061 gctacaaaga agtagacggc aaaaaagtcc gtgtttctaa aaaaaccggt gaagttttag
    51121 ataaataaaa gtttaaggaa ggagggtctt actgaatgaa ccgcctaaaa gaaaaatatc
    51181 ttaaagaagt aactccatca ttgatggaaa aatttaacta tagctctgtt atgcaaacac
    51241 ctaaagttga aaaaatcgtc atcaacatgg gtgttggtga tgcggtatca aacgctaaaa
    51301 acttagataa agcagttgaa gaattaactt tgatcactgg tcaaaaacca atgattacaa
    51361 aagctaaaaa atcaatcgct ggattccgtt tacgtgaagg aatgccaatt ggtgcaaaag
    51421 ttacattgcg cggagaaaga atgtacgaat tcttagacaa attggtttct gtttcactac
    51481 cacgtgtacg tgacttccat ggtgtaagta aaaaagcctt tgacggtcgt ggaaactata
    51541 ctttaggtat taaagaacaa ttgatcttcc cagaagtaga ttatgattta gtagataaag
    51601 tacgtggtat ggacatcgtt attgtaacaa cagcaaactc tgatgaagaa tctcgtgagt
    51661 tgttgacaca attaggcatg ccattccaaa aataattaaa ggaggcgaac tacgtggcta
    51721 aaaaatcaat gattgctaaa aacaaacgtc ctgcaaaatt ttcaacacaa gcttatactc
    51781 gttgcgaacg ttgcggacgt ccacattcag tttatcgtaa gttccatctt tgccgtattt
    51841 gcttccgcga acttgcctat aaaggtcaaa ttcccggcgt gaagaaagct agctggtaaa
    51901 aagtaaattc gcataagaag gaggtaaaag atcaatggtc atgacagatc caattgcaga
    51961 ttttctaact cgtatccgta acgcaaacat ggttaaacat gagtctttag aagtacctgc
    52021 atcaaaaatt aaacgtgaca tcgctgaaat cttgaaacgt gaaggtttcg ttcgtgatgt
    52081 tgaatacatc gaagatgaca aacaaggcgt gatccgtgtt ttcctaaaat ttggtaaaaa
    52141 cggcgaacgt gttatcacaa acttaaaacg tatctctaaa ccaggtttgc gtgcttatgt
    52201 caaagctgac gaagtaccaa aagtattgaa cggtttaggt atcgcaatca tttcgacttc
    52261 tgaaggtgtt gtcactgata aagaagctcg tgaaaaaaat atcggcggcg aagttatcgc
    52321 ttacgtatgg taatcaagta gaatctacaa ggaggtgtct ttaagtgagc cgtatcggaa
    52381 ataaagtcgt tgttatccct gaaggagtaa cagttactca agacggaaac aacgttacag
    52441 ttaaaggacc aaaaggtgaa ttgactcgta ctttttcagc agatatcaaa atgaatatcg
    52501 aaggaaacga agtaactttc actcgtccaa acgacagtaa agaaatgaaa acaattcatg
    52561 gaacaactcg tgcgaacttc aacaacatgg ttgtaggtgt cagcgaaggt ttccaaaaag
    52621 cgttagaact aatcggggtt gggtaccgtg cacaattaca aggatcaaaa cttgtattga
    52681 acgttggtta ctcacatcca gtagaaatca caccaccagc tggagtaact gttgaagtac
    52741 cagctaacac acaagtaatt gttaaaggtg cgaacaaaga agaagttggc gaattagctg
    52801 caaacattcg tggaactcgt cctccagaac cttataaagg taaaggtatt cgttatgttg
    52861 gcgaatatgt acgccgtaaa gaaggtaaaa ctggtaaata atcgtttaga aaaattgcat
    52921 agaagccagc agcaggaaaa aggcatttgg ctgaagttta ccttcaaaaa aatacatttt
    52981 tacttgtgcc gcagcttcta tttttcgaaa cgtatttact gcttgaaata gtagtacaat
    53041 aaaaataaag aggtgacaat tgtgattaca aaaccagata agaacaaaac acgtcaaaag
    53101 agacatcgtc gtgtacgtaa caatatctct ggtactgctg agcgcccacg cttgaacgtt
    53161 tttcgttcta acaaaaacat ctacgctcaa attattgatg acgtagcggg tgtaacgcta
    53221 gcaagtgcct ctaccttgga taaagaaatt tcaggtggaa caaaaacaga agcagcacaa
    53281 gctgtcggta aactagttgc tgaacgtgca gctgaaaaag gcattaaagt agtagtcttt
    53341 gaccgtggtg gataccttta ccatggccgt gtgcaagctt tagctgaagc tgctcgcgaa
    53401 aatggactag aattttagaa gaaggaggaa taccattcat ggtttatatc gatccaaaac
    53461 atttggaatt agaagaccgc gttgttgcaa ttaaccgtgt aacaaaagtt gttaaaggtg
    53521 gacgtcgtct acgttttgct gctttagttg ttgtcggtga caaaaacgga cacgtaggat
    53581 ttggtacagg taaagctcaa gaagttcctg aagcaatccg taaagcaatt gaagatgcga
    53641 agaaaaactt agttgaagta cctatggttg gttcaacaat cccacacgaa gtaatcggtg
    53701 cttttagtgg tggtagaatc ctaatgaaac ctgctgtaga aggttctggg gttgctgctg
    53761 gtggaccagt tcgtgccgta ttagaattag ctggggtagc agatatcact tctaaatctt
    53821 taggctcaaa tacaccaatc aacgttgttc gcgcaacagt tgaaggtttg aaacaattga
    53881 aacgtgcaga agaagttgca gaacttcgcg gcaaatcagt tgaagaatta atcggataag
    53941 gaggacaaca ataatggctg aattaaaagt tactttaaaa cgcagtatta tcggacgtcc
    54001 tcaaaaccaa cgcgatacag ttaaagcgtt aggtcttaca aagattaaca gttcagtggt
    54061 taagccttct aatgaagcaa ttaaaggcat gatcaatact gtttctcacc tagtggacgt
    54121 tgaagaaatt taatttagaa aaatcataac tagaacatta aggaggtgcc aaacctatga
    54181 aacttcatga attaaaacct gctgaaggtt cacgccaagt acgtaaccgt gttggtcgtg
    54241 gtacttcatc tggtaacgga aaaactgccg gacgcggaca aaaaggacaa aaagctcgtt
    54301 caggcggcgg tgtgcgttta ggatttgaag ggggacaaac accattgttc cgtcgtttac
    54361 caaaacgagg attcacaaac gtgaaccgta aagactatgc agtcattaat cttgatgtat
    54421 tgaaccgctt tgaagacgga gctgaagtaa ctcctgttgc tttagttgaa gctggaatcg
    54481 tgaaaaacga aaaagctgga atcaaagtat tagctaatgg ggaactaaac aagaaattaa
    54541 ctgtgaaagc agcaaaattc tctaaagcag ctcaagaagc aattgaagcg gctggtggat
    54601 caatcgaggt gatctaatgt ttagactatt aaaagatgct tttaaagtaa aagacattag
    54661 atcgaaaatc ctatttactg tatttgtgtt gtttgtattt cgcctaggtg cacatattac
    54721 tgtaccaggc gtaaatgctg cttcattgca aaacctttct tctttgccat ttttcaacat
    54781 gttgaacttg gtaagtggta gtgcgatgca aaacttttcc attttctcaa tgggggtttc
    54841 accatacatt actgcttcta tcgtcattca gcttcttcaa atggacatcg tgcctcgatt
    54901 tgttgaatgg tcgaaacaag gggaagttgg tcgtaaaaaa ctgaatcaag cgactcgata
    54961 tctgacatta gtattggcat ttatccaatc tgtcggtatc actgctggat tcaatcaata
    55021 cgctcaatta ggtttcgtga ataatcctaa cgtagcaact tacgtaacga tcggtttgat
    55081 tctaacagcc ggtacgatgt ttgttacttg gctaggagaa cagatcacag aaaaaggtat
    55141 cggaaatggc gtatcaatga tcatttttgc aggtatcatt tctagattgc ctgaaagtat
    55201 cagagaaatt tatgaagatt actttataaa tattgatcct tcagacatat ggaaatctgc
    55261 tatttttgtg gccattttac tagtagcggt cttgttgatc gtgacattcg taacattttt
    55321 ccaacaagct gaacgcaaga tcccgatcca atatacgaaa cgcgtagctg gcgcgcctac
    55381 aagcagctat ctgccgttga aagtaaatgc agctggagtt attccagtta tctttgctag
    55441 ttcgtttatt gctacgccaa atgctgtttt acaagcattg agcggtagat tcggttctga
    55501 aaactggtac aaagtgatga tggagatctt taactataat acagcacctg gtgctacgat
    55561 ttatacgatt ctgatcgttg ccttcacttt cttctacgcc tttgttcaag taaaccctga
    55621 gaaattagcg gaaaacttgc aaaagcaagg aagttatata ccaagcgtac gccctggtaa
    55681 ggggactgaa gagtatgtct caagattact gatgcgttta agtacagttg gtgcagtctt
    55741 ccttggttta gtggcattgc ttccaatcat tgctcaaatg gtttgggatc ttccacaatc
    55801 aatcggatta ggcggtacaa gcttactgat cgttatcggt gtagctttag aaactgcgaa
    55861 acagttagaa ggcttaatgc tgaaacgtaa atatgttgga ttcattgagt aagaaagcgt
    55921 gttgaggttt cccctcaaca cacgttctca cacatttatt aggagggaaa acaatgaacc
    55981 tcattttaat ggggctgcca ggcgcaggta aaggaacaca agctgaaaaa atcattgatg
    56041 cttatggtat tccgcacatc tcaacaggag atatgttccg cgcagcgatg caaaacgaaa
    56101 cagctcttgg cctggaagca aagtcttata tggataaagg tgcattagtt cctgatgaag
    56161 taacaaatgg aatcgtgaaa gagcgactag ctgaaccaga tacagagaaa ggcttcttat
    56221 tagatggctt tccacgtacg ctagatcaag caaaagctct ggacgcaatg ctaaaagatt
    56281 tgaataaaaa aattgatgct gtcatcgata tccatgttgg tgaagaaatc ttggtcgaac
    56341 gtctagccgg ccgatttatc tgcagcaatt gtggagcaac ttaccataaa attttcaacc
    56401 ctacaaaagt tgaagacaca tgtgatcgtt gcggtgggca tgaattctat caaagagaag
    56461 atgataaacc tgagacggtt aaaaatcgtc tggctatcaa catcaaaaat agtgaaccaa
    56521 tcttggctta ttataaagaa caaggtttgc taaacactat tgatggtgct cgtgaaatcg
    56581 atgctgtatt tgcagatgta caaaaaatca ttgaaaaata gcacgattgc ccgtagccga
    56641 cttgcattat gcagttactc ttgtcaagtt caataaatta tgatagaata tgtcagtccg
    56701 acttctagag aatcctctag atgatccatt ttgagaattt tgaggtggga actgcagttt
    56761 ccgccatttt atcgtgtgaa aatgcgaaac aagtacaagg aggtactgtg cgtggcaaaa
    56821 gaagatatga ttgaagtcga aggtacagtc gtcgaaactt tgccgaatgc aatgtttaaa
    56881 gttgaactag aaaacggaca ccaagttctt gctactgttt caggtaaaat tcgtatgcat
    56941 tacatccgta tcttacctgg tgacaaagta acggttgaat tgtctccata cgatcttaac
    57001 cgtggccgta ttacttatcg ctttaaataa ttgtactccg taaaactaca ggaggtatta
    57061 tcatgaaagt aagaccatca gtaaaaccaa tgtgcgaaca ttgtaaagta attcgtcgta
    57121 aaggacgcgt tatggtgatt tgcccagcaa atccaaaaca taaacaacgt caaggataat
    57181 tggaggtgct ataaatatgg ctcgtattgc aggagtagat attcctcgtg ataaacgtgt
    57241 agtagtttca cttacttata tctatggtat tggtaacact actgctaaaa agatcttagc
    57301 tgatgctggt gtatctgaag atgttcgcgt tcgtgaatta acgaatgaac aaacagatgc
    57361 tatccgtgca gaagtagata aattaaaagt tgaaggggat cttcgtcgtg aagtgaactt
    57421 gaacatcaaa cgtttgatgg aaatcggttc ttaccgtgga atccgtcatc gccgtggatt
    57481 gcctgttcgt ggacaaaaca cgaaaaacaa tgcacgtact cgtaaaggcc cagctcgcgc
    57541 tatcgctggc aagaaaaaat aattcttaag tgaaggaggt taaaacttca tggcagcaaa
    57601 aaaagtgaat cgtaaacgcc gtgtgaagaa gaatatagaa gcaggtattg cacatatcca
    57661 ttctacattc aataacacta tcatcatgat cactgatact cacggaaatg cattagcgtg
    57721 gtcatcagct ggttcattag gtttcaaagg aagcaaaaaa tcaactcctt ttgccgctca
    57781 aatggcagca gaaactgcta caaaagcagc aatggaacac ggattaaaga ctgttgaagt
    57841 aacagttaaa ggacctggtt ctggacgtga agcagcaatt cgttcattac aagctacagg
    57901 tttagaagtg actgcaattc gtgacgtgac tccagttcct cataatggtg cccgccctcc
    57961 aaaacgccgt cgtgtttaat gagtgccgct cattttgagt tttatcagta acgtcattga
    58021 acaagacact tttcgttttg aaaggggtaa agataagaat gattgagttc gaaaaaccaa
    58081 gaatcgcaaa aattgatgaa gaaaaagatt atggcaagtt catcgttgaa cctcttgaaa
    58141 gagggtatgg gactacttta gggaattccc tacgtcgtat tttattatct tctttgccag
    58201 gtgctgccat cactaatatt caaatcgatg gtgtactgca tgaattctct accatcaaag
    58261 gtgttagaga agacgtcact caaatcatct tgaacattaa aggcttagcg ctgaaaatgt
    58321 atggccaaga agaaaaaacc cttgaaatcg atattaccgg acctgctaca gtaactgctg
    58381 gcgatattat cgttgatagt gatgtagaaa ttcttaacaa agatatgtac atctgtagtg
    58441 tctctgaagg agctacgttc catgctcgct taacagtgaa acctggacgt ggttatgttc
    58501 aagcagatga aaataaaaaa gaagatatgc caattggcgt tcttccagtc gattcaatct
    58561 acacacctgt tcgtcgtgtg aactatcaag ttgagaacac acgtgttgga caccgtgaag
    58621 attttgataa attgacgatg gagatttgga cagatggttc aattgaaccg ttggaagcaa
    58681 tgagtttgtc tgcgaaaatc atgactgaac atttggatat ttttgtgaac ttaactgatg
    58741 aagcaaaaaa tgctgaaatc atggtcgaaa aagaagaaac acaaaaagaa aaaatgttgg
    58801 aaatgacgat cgaagagtta gacttgtctg ttcgctctta caattgtttg aaacgtgcag
    58861 gaatcaatac tgtacaagaa cttacaaata aatctgagcc tgaaatgatc aaagtccgta
    58921 acttaggacg taaatcatta gaagaagtta aagcaaaatt gcacgactta ggtttaggtt
    58981 tacgtaaaga agattaaaac cttttacgaa ggagggaaac caacgtgagt tatcgtaaac
    59041 taggacgcac atctagccaa cgtaaagcga tgttgcgtga tttaacaact gatttattaa
    59101 tcaacgaacg tattgtgact actgaagctc gtgcgaaaga agttcgctca actgcagaaa
    59161 aaatgatcac tttaggtaaa cgcggagatt tgcatgcacg tcgtcaagct gcggctttcg
    59221 tacgtaatga agttgccagc gtgcgtgaag aaaatgagga catcgtcatt gaatcagctt
    59281 tacaaaaact gttcaacgat attgcacctc gttacgcaga acgtcaaggc ggatacacac
    59341 gcattttgaa gacagaacca agacgcggtg atggtgcacc aatggttgtc ttagaacttg
    59401 tctaaaatca cactaataac atcactttat agatgattct tttagagtgt tatgatgttg
    59461 gaagatattt ttccgagtct agctcagcgc tgctcctcaa gcgaatatcg cttggggagt
    59521 aagcactcat cataaagtgt ttttttatac cttcaattac ctgtcatgac agatatgttt
    59581 gaaggcataa aaaaacattt taagcgagaa ataattgaaa attttgtctt tttttgatag
    59641 tgttagtagg aactttagga tgaagaagga gtaatcatgg agccaattat tgaattagaa
    59701 aagataaatt ataaatacca gccagatgat cttcgccccg cattgaaaga tgtctccttt
    59761 acaattgata aaggtgagtg gatcgctatt attggacaca atggttcagg aaaatcgaca
    59821 cttgccaaaa cgatcaatgg attgcttctg ccagaatcag ggatcgtgaa agtgggaaat
    59881 caaatattgg atgaagaaaa tatttggacg atccgacaga tggttggaat ggtttttcaa
    59941 aatccagaca atcagtttgt tggttcgaca gtagaagatg acgttgcttt tggtcttgaa
    60001 aatcaaggga ttcccagaga agaaatgcta gtgcgtgtga aagatgcact tgagaaagtt
    60061 agaatggctg agtttgcttc acgcgagcct gctcgtttat caggagggca aaaacaacgt
    60121 gttgccattg ccggcgtggt tgccttacga cctgatatca ttattttaga tgaagcaacc
    60181 agtatgctag atccagaagg tcgtgaagaa gtgatctcta cgatcaagaa gatcaaagaa
    60241 gaaagtcaat tgaccgttat atctatcact catgatattg atgaagcagc taatgccaat
    60301 cggatactag tgatgagaca aggcgaactt gtccgtgaag gtacaccaaa agaaattttt
    60361 tctgctggtc ctgaactgat cgacttaggt ctagatctac catttcctga aaaactgaag
    60421 agcgcactga aagaacgtgg ggttgatgtg cccagtgaat atatgacaga agaaaggatg
    60481 gtggattggt tatggacatc cgttttgaac aagtagactt cacttatcag ccgaatacac
    60541 catttgaaca aagagcctta tttgacatca atatgacgat caaagaaaac agttatactg
    60601 cattagtagg gcataccgga agcgggaaat caaccttact tcagcatttg aatgcgcttg
    60661 ttaagccaac aagcggtaca gtccatattg gagaacgaga tattcagccg gatacggata
    60721 ataagaattt aaagcccatc cgaaaaaaag ttggcatcgt ctttcagttt ccagaagcac
    60781 agctattcga agaaacggta gcaaaagaca ttgctttcgg tcctaaaaac tttggtgtca
    60841 gcgaagaaga agcactagtc ctagcaaaag aaacattaga acaagttggg ctggatgaaa
    60901 gctatttgga acgttcgcca tttgaacttt caggagggca aatgcgtaga gtagcaatcg
    60961 ctggtgtgct tgccatgagg ccggaagtac ttgtattgga tgaaccaacg gcaggacttg
    61021 atccccaggg cagaaaagaa atgatggaga tgttttggcg tcttcataag gaacagcaga
    61081 tcactattgt attagttacg catttaatgg atgatgtagc caattttgca gattatgtct
    61141 atgtgttgga aaagggacga atcgttaata gcggggagcc gcaagaggtc tttcaaaaca
    61201 ttgaatggct aaaagaaaaa caactaggcg tacctactgc caccgagttt gcagaagaat
    61261 taatggctaa agggatgaac tttgctacct tgcctttgac agctgaagaa ttagcagacg
    61321 ctatcgtcca ttatgctgga ggaaatgccc atgatgaata aattgatatt tggtcgttat
    61381 atgcctggag attccttgat ccatcgattg gatccccgag ctaaattatt agccagtttt
    61441 tattttatcg gaatcatttt tttagcaaat aattgggaaa cgtacctttt gttggcattt
    61501 ttcacattac tttctgtctt cttgtcaaaa gtagatttga aattttttat ccgaggcatt
    61561 cgcccattga tctggctaat cctcttcact gtagctttgc aggtcttgtt tacaagtggc
    61621 ggagaaactt attggagttg gggtgttttc catatcactg aatttggtgt gatgaacggc
    61681 ctctttattt tctgtcgatt cgtgttgatc atttttatgt cgactctact cacgcttact
    61741 acaccgcctt tggaattatc ggatgcgatt gagtacttgc ttcgtccatt gaaagccgta
    61801 cggttcccag tccacgaaat ttcattgatg ctgtcgattg ctcttcgttt tgtgcctaca
    61861 ttgatggacg aaacagaaaa gatcatgaac gctcagcgcg ctcgcggtgt tgattttggt
    61921 gaaggaaacc tagttcagaa aatgaaagca gtcattcctt tgctgattcc tttatttgtc
    61981 agcagcttca accgtgcgga agatcttgcg actgctatgg aagcaagagg ctacaaaggt
    62041 ggggaaggaa gaacgaaata tcgtgtattg cattggcata atagagacac gatggttatc
    62101 attgcttttg tattattaac tgtgctactg atctttttaa gaggataaac gttcagtggg
    62161 ccgctatcta ttcttttctt gctgatctgt ttgcaagaaa ggatgcaagc agtgtatgac
    62221 aagaaatatt agggtctgtg gcagactaag gtcacaggcc tctttctttt atctgaaaag
    62281 aaagaacgaa aaaattttat agaaaaatca ttattccaga taacctttta ggaacaaagg
    62341 agagaaaaac atggtacgtt acaaagcaat cattgcgtac gacggaacaa attttaatgg
    62401 attccaaaaa cagccaaatg ggcgtactgt tcaagaagaa gtagaaaaaa cattacaaaa
    62461 aatggcaaat ggaaaagaaa tcacggtctt tggttcggga aggacagatg ccggagtaca
    62521 tgcgatcggg caagtaatcc attttgatta tccagaggag cgtccgttag aacgaatgcg
    62581 tttcgcgcta gatacccagt caccagagga tattgctgta agacaagtag aaattgtttc
    62641 agaagacttc cacgcaagat atttggtcaa agaaaagacg tatcaatttc gagtggatat
    62701 agggaaacca cgcagtcctt ttcgacgcca ttatgcaagt tattttcctt acccacttga
    62761 tttggaaaaa attcagcggg cgcttcctga tttattaggg actcacgatt tcacctcttt
    62821 ttgtgcatca ggaagctcga tagaggataa aatacgtacg atctacgagg ctaagatgga
    62881 ggtaaatgaa acaaaagacg aattgttgtt tacatttagg ggaaatggct tcttgtataa
    62941 gatgatacgg atcttagtag gaacgctttt gaaaattggc aatggccgat tgcctgaaga
    63001 tagtatccca gatattattg cgaaaaaaga tcgtaatgca gcaggaccta cagcacaccc
    63061 tgaaggactt tatttgtatg aagtgaaata tgaataagag gttatgatag aagtggtcag
    63121 cttcaagaaa taagaaggta tttacgaaaa ttacttctca aaattttgca aaatttcggc
    63181 ttattttcga agaagctact tctggaacac cgtttaagga agaggtcgtg aaatcagcgt
    63241 tttgacctga gtattagaga aacaaacggg aaaatagctc ctcatatttt gccgtttgtt
    63301 gagctaatat cgaaggtcag ctgattgaac accgtttaag aaagaggtcg tgagcctgtc
    63361 atttaactct gagtcacaaa gagcaatttc aaaaaacagc ttctcatctt tgatgaatat
    63421 cgtgacttgt ggacgaggcg ttgataagtg aatcatcttt ttgttaccta ttttttctgt
    63481 aaccaaaaaa cgatggaacg ttgttttgat tgcccttggt gcggacagtc tgaacaggtt
    63541 ccatcgtttc tttattttct acgtcttctt ctgtgtgtgt ttcgtggttg ttcttctatt
    63601 gctggatcaa tcgtgccata aaaggggcga ttgcggtcaa ggtaccagac ataaagaata
    63661 aacaatgcaa tacataggac aaaaaggatt gcacctatcg taaatccttc aggcaagtaa
    63721 ctgaaagtga cagtatgttt acctgctgga acttttatca tcaagaatgc gtctttgaaa
    63781 ttgctgacct tgactggttt cccatcaatt ttagctttcc atcctttgtc ataaggaata
    63841 gttgtcacca acatggaatc ttcagcggta tttacagtcc cagaagcttt tctgccagtg
    63901 gcttccattt cgacaccttt ttctttgatc tgattcattg cggcttgata ggctacaaca
    63961 tctagaccaa cgactttagg ctccatgaaa cttatttctt tcgtcccata aaaacttgca
    64021 gtaaatgtca ctgttgtctc ttgaggataa tagccaagat catagtattg accagaaatg
    64081 ttgatttgcg tttttcgcga tgtaccattg acagtgatcg tcgcactaga actttctaat
    64141 tgcgcaaaat tggttgggaa caaacttaag taagcttgtg tatttgcagg cacatggact
    64201 tcccaagtga gctcttttgg ctggttatct gctgtttctg agtaagtgac gccagtcgtt
    64261 gtctttgtga tcgtcgtatt caactgattc ttcaaagtag gtgtatagaa tgtaaaatac
    64321 tgttcattta gaccagacaa tgtattgatc aagtttgtct gactggtcaa attatctgtc
    64381 actggctgct caacatcatt aacggacaac ggtgcagtaa atgctagtgg caatgcattg
    64441 acattctgat acagtgtata gtcgccgctt tgaccagctt ggcggaagcc atatttactg
    64501 aacgtgcttt cgtttttaga aatgttatat ttgattcctg taaacccatc catcagcaaa
    64561 gtattattgt tataacggat attcaaattt gtccctcttg aacggaaacc taatttatcc
    64621 aggtaagagg aagaattacg atttcttata gaagaaaaca aactgatacc actgtaacca
    64681 tagttgatcg aatcgtttgc agatactgga tccagatttt ccaagcggta aaacgagtcg
    64741 gaatcttttt ttgtttcatt tacaagagct ttcaagtcag gataaggatc agtatataaa
    64801 ctgcgggaag cataattcca atcatcaaga atgccatgga tcatactgtt cgtattgacc
    64861 agtgcttcag cagacatgat caataataac aatatactca gatgattgaa tgaaagtttt
    64921 ttatgctgat aaaatcccac agcaaaagca taaatcccta agaaaaccac tgtcaataca
    64981 aaggaagtca tcgtcacata ggtgtagctt ccttcaggtt tgatgcccca tgccaccgca
    65041 aagagagcag ctacgaccaa aatgattcct aacaacagcc cacgatcgtc ttgttctatc
    65101 ttttcccatc cttttcctgc aagcaggagc actaagaaag agaacagata ggcataacgg
    65161 aataaaaaca tattcggtgc atgcatacca tgccagaaca aattcaatgg aacaagataa
    65221 aaacttgcga taagtatggc gaaaagactg ccgtacaaaa atttattttt caacggtact
    65281 ttccgactgg caaaataaaa cagacagagg actaatggta gcagacctgc gtaaacgaac
    65341 ggaatcgatc cgtattttgt cgtgtcataa acaccaatca tatttttcat gattagatcc
    65401 agataagaag tcgcttctgt tttcaacgta gtgatctgac tcagtgcctc gccatttgac
    65461 cgaagatcca gcactgctgg caatacaatg atcattgaag cgccgcctgc cagtaaagaa
    65521 gtgataccat aaggaacaat cgttttttta tattctgacc agtttgtcaa tagacgggcg
    65581 ataaaatata agaaagaaaa tacgccaatc ataaaaccca tataaaaact ggataaaaac
    65641 aagagtaaat aactgataaa taaaagtttc ggccgtttaa gatccataac acgatgaatc
    65701 cccaaaatca ctaatggaag ataaaaaaat gcatccagcc acatgatgat ctccgaatgt
    65761 gcagtgataa atgagatcaa tgcgtaactg acgctaagtg caacatgccc ccagcgagga
    65821 atcttgaacg tacgtgcaag aaaccaaaaa gccaatccgg cacagccgac cttaagcaaa
    65881 gtcagaacat acagtgcatc tggcatcatc tggtttggaa aaaagaacac cagtggcgtg
    65941 aagatcccgc ctagatagta agaaattaaa gataaataat tcaatcctag agaagcattc
    66001 catgtataaa aaatactttg ctttccaaga agaacatttc ggaagctggc atgaaaatta
    66061 gaaaactgtg aaaaggcatc acttgccaaa atacttctgc tgcttccagg atagattccg
    66121 atacttagat aaacaagtgc taaaatcaaa aacggaatca ggaaactagc tgctgcgtag
    66181 cgtccgtttt ctctaaagaa tgactttaaa ttttttttca tatttatttt ccaccaaatt
    66241 tctatgaagt tgtattcagt ttatcatatc cttgtttttc tctgcttaaa aa
//
LOCUS       DBBGSZ010000013        61527 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.013, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000013 DBBGSZ010000000
VERSION     DBBGSZ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 61527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.013"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..2327)
                     /gene="esp"
                     /locus_tag="ACIZE5_001156"
     CDS             complement(<1..2327)
                     /gene="esp"
                     /locus_tag="ACIZE5_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HGC6108315.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
     gene            complement(2944..3378)
                     /locus_tag="ACIZE5_001157"
     CDS             complement(2944..3378)
                     /locus_tag="ACIZE5_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108316.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3395..4600)
                     /locus_tag="ACIZE5_001158"
     CDS             complement(3395..4600)
                     /locus_tag="ACIZE5_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HGC6108317.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            5294..5680
                     /locus_tag="ACIZE5_001159"
     CDS             5294..5680
                     /locus_tag="ACIZE5_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGC6108318.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            5774..5965
                     /locus_tag="ACIZE5_001160"
     CDS             5774..5965
                     /locus_tag="ACIZE5_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6108319.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            6479..6811
                     /locus_tag="ACIZE5_001161"
     CDS             6479..6811
                     /locus_tag="ACIZE5_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGC6108320.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            6721..6915
                     /locus_tag="ACIZE5_001162"
     CDS             6721..6915
                     /locus_tag="ACIZE5_001162"
                     /inference="COORDINATES: protein motif:HMM:NF024673.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGC6108321.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKC"
     gene            6954..7100
                     /locus_tag="ACIZE5_001163"
     CDS             6954..7100
                     /locus_tag="ACIZE5_001163"
                     /inference="COORDINATES: protein motif:HMM:NF012870.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108322.1"
                     /translation="MMDITYIPCNDGRLYLSTYIDLATRILRYYMVDSHMKKEIVVRP
                     LQIY"
     gene            7107..7262
                     /locus_tag="ACIZE5_001164"
     CDS             7107..7262
                     /locus_tag="ACIZE5_001164"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HGC6108323.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            7538..8878
                     /locus_tag="ACIZE5_001165"
                     /pseudo
     CDS             7538..8878
                     /locus_tag="ACIZE5_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9119..10735)
                     /locus_tag="ACIZE5_001166"
     CDS             complement(9119..10735)
                     /locus_tag="ACIZE5_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HGC6108324.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            10853..11071
                     /locus_tag="ACIZE5_001167"
     CDS             10853..11071
                     /locus_tag="ACIZE5_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6108325.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            11266..11727
                     /locus_tag="ACIZE5_001168"
     CDS             11266..11727
                     /locus_tag="ACIZE5_001168"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC6108326.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(11920..12159)
                     /locus_tag="ACIZE5_001169"
     CDS             complement(11920..12159)
                     /locus_tag="ACIZE5_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6108327.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(12183..13706)
                     /locus_tag="ACIZE5_001170"
     CDS             complement(12183..13706)
                     /locus_tag="ACIZE5_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HGC6108328.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(13724..13846)
                     /locus_tag="ACIZE5_001171"
     CDS             complement(13724..13846)
                     /locus_tag="ACIZE5_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HGC6108329.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(13876..14859)
                     /locus_tag="ACIZE5_001172"
     CDS             complement(13876..14859)
                     /locus_tag="ACIZE5_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HGC6108330.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(14883..15032)
                     /gene="rpmG"
                     /locus_tag="ACIZE5_001173"
     CDS             complement(14883..15032)
                     /gene="rpmG"
                     /locus_tag="ACIZE5_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGC6108331.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(15053..15430)
                     /locus_tag="ACIZE5_001174"
     CDS             complement(15053..15430)
                     /locus_tag="ACIZE5_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108332.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(15462..15641)
                     /gene="rpmF"
                     /locus_tag="ACIZE5_001175"
     CDS             complement(15462..15641)
                     /gene="rpmF"
                     /locus_tag="ACIZE5_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HGC6108333.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(15656..15925)
                     /gene="rpsN"
                     /locus_tag="ACIZE5_001176"
     CDS             complement(15656..15925)
                     /gene="rpsN"
                     /locus_tag="ACIZE5_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HGC6108334.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(16448..18214)
                     /locus_tag="ACIZE5_001177"
     CDS             complement(16448..18214)
                     /locus_tag="ACIZE5_001177"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6108335.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(18174..19928)
                     /locus_tag="ACIZE5_001178"
     CDS             complement(18174..19928)
                     /locus_tag="ACIZE5_001178"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6108336.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(20038..20607)
                     /locus_tag="ACIZE5_001179"
     CDS             complement(20038..20607)
                     /locus_tag="ACIZE5_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGC6108337.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(20625..22040)
                     /locus_tag="ACIZE5_001180"
     CDS             complement(20625..22040)
                     /locus_tag="ACIZE5_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6108338.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(22051..22719)
                     /locus_tag="ACIZE5_001181"
     CDS             complement(22051..22719)
                     /locus_tag="ACIZE5_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGC6108339.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(22849..23433)
                     /locus_tag="ACIZE5_001182"
     CDS             complement(22849..23433)
                     /locus_tag="ACIZE5_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6108340.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(23764..23997)
                     /locus_tag="ACIZE5_001183"
     CDS             complement(23764..23997)
                     /locus_tag="ACIZE5_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HGC6108341.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(24012..24962)
                     /locus_tag="ACIZE5_001184"
     CDS             complement(24012..24962)
                     /locus_tag="ACIZE5_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein"
                     /protein_id="HGC6108342.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(24959..25801)
                     /locus_tag="ACIZE5_001185"
     CDS             complement(24959..25801)
                     /locus_tag="ACIZE5_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HGC6108343.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(25803..26522)
                     /locus_tag="ACIZE5_001186"
     CDS             complement(25803..26522)
                     /locus_tag="ACIZE5_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGC6108344.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            27070..27360
                     /locus_tag="ACIZE5_001187"
     CDS             27070..27360
                     /locus_tag="ACIZE5_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003013637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6108345.1"
                     /translation="MTIAANNDTSVRLAVNWGEVKFLCAYPKQFKNFITTILGDDFIE
                     SRVYLNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKDFMNT"
     gene            27432..28658
                     /locus_tag="ACIZE5_001188"
     CDS             27432..28658
                     /locus_tag="ACIZE5_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6108346.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(28746..29138)
                     /gene="rpsI"
                     /locus_tag="ACIZE5_001189"
     CDS             complement(28746..29138)
                     /gene="rpsI"
                     /locus_tag="ACIZE5_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HGC6108347.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(29154..29582)
                     /gene="rplM"
                     /locus_tag="ACIZE5_001190"
     CDS             complement(29154..29582)
                     /gene="rplM"
                     /locus_tag="ACIZE5_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HGC6108348.1"
                     /translation="MAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPTFTPHL
                     DTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLIETSVK
                     GMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(30116..30583)
                     /locus_tag="ACIZE5_001191"
     CDS             complement(30116..30583)
                     /locus_tag="ACIZE5_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HGC6108349.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(30703..32241)
                     /locus_tag="ACIZE5_001192"
     CDS             complement(30703..32241)
                     /locus_tag="ACIZE5_001192"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046316 - gluconokinase activity [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HGC6108350.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            32321..33007
                     /locus_tag="ACIZE5_001193"
     CDS             32321..33007
                     /locus_tag="ACIZE5_001193"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HGC6108351.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(33208..33735)
                     /gene="msrA"
                     /locus_tag="ACIZE5_001194"
     CDS             complement(33208..33735)
                     /gene="msrA"
                     /locus_tag="ACIZE5_001194"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HGC6108352.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(33819..34496)
                     /gene="pgmB"
                     /locus_tag="ACIZE5_001195"
     CDS             complement(33819..34496)
                     /gene="pgmB"
                     /locus_tag="ACIZE5_001195"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HGC6108353.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(34493..35623)
                     /locus_tag="ACIZE5_001196"
     CDS             complement(34493..35623)
                     /locus_tag="ACIZE5_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HGC6108354.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(35623..37806)
                     /locus_tag="ACIZE5_001197"
     CDS             complement(35623..37806)
                     /locus_tag="ACIZE5_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HGC6108355.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQGDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(37803..38828)
                     /locus_tag="ACIZE5_001198"
     CDS             complement(37803..38828)
                     /locus_tag="ACIZE5_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC6108356.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(38873..39700)
                     /locus_tag="ACIZE5_001199"
     CDS             complement(38873..39700)
                     /locus_tag="ACIZE5_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HGC6108357.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(39697..40764)
                     /locus_tag="ACIZE5_001200"
                     /pseudo
     CDS             complement(39697..40764)
                     /locus_tag="ACIZE5_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
     gene            complement(40790..41626)
                     /locus_tag="ACIZE5_001201"
     CDS             complement(40790..41626)
                     /locus_tag="ACIZE5_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6108358.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(41623..42492)
                     /locus_tag="ACIZE5_001202"
     CDS             complement(41623..42492)
                     /locus_tag="ACIZE5_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6108359.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(42562..43845)
                     /locus_tag="ACIZE5_001203"
     CDS             complement(42562..43845)
                     /locus_tag="ACIZE5_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6108360.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(43859..45544)
                     /locus_tag="ACIZE5_001204"
     CDS             complement(43859..45544)
                     /locus_tag="ACIZE5_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HGC6108361.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGTRVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            45819..46844
                     /locus_tag="ACIZE5_001205"
     CDS             45819..46844
                     /locus_tag="ACIZE5_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6108362.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(47439..51092)
                     /gene="rpoC"
                     /locus_tag="ACIZE5_001206"
     CDS             complement(47439..51092)
                     /gene="rpoC"
                     /locus_tag="ACIZE5_001206"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HGC6108363.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(51171..54788)
                     /gene="rpoB"
                     /locus_tag="ACIZE5_001207"
     CDS             complement(51171..54788)
                     /gene="rpoB"
                     /locus_tag="ACIZE5_001207"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGC6108364.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            55516..56484
                     /locus_tag="ACIZE5_001208"
     CDS             55516..56484
                     /locus_tag="ACIZE5_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6108365.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            56502..57407
                     /locus_tag="ACIZE5_001209"
     CDS             56502..57407
                     /locus_tag="ACIZE5_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6108366.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            57404..58210
                     /locus_tag="ACIZE5_001210"
     CDS             57404..58210
                     /locus_tag="ACIZE5_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6108367.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            58367..59335
                     /locus_tag="ACIZE5_001211"
     CDS             58367..59335
                     /locus_tag="ACIZE5_001211"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HGC6108368.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDVKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(59652..60176)
                     /locus_tag="ACIZE5_001212"
     CDS             complement(59652..60176)
                     /locus_tag="ACIZE5_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HGC6108369.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            60463..>61527
                     /gene="scm"
                     /locus_tag="ACIZE5_001213"
     CDS             60463..>61527
                     /gene="scm"
                     /locus_tag="ACIZE5_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HGC6108370.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        18662 a        12347 c        10306 g        20212 t
ORIGIN      
        1 cctgcggtga aggttacttt gtggtagcct gcaggaatgt tttctcctgg attttcataa
       61 atatctttac ttacagttac tgctaaatcg gtcgtgccta cagaaccatc ttggtaaaca
      121 attttaatag gaattgttcc agtaatcggc tccgattctc ctacaccttt agctggagtg
      181 aatgtaacaa taccagtgtt tgcatcaaca cttgcattac cgaagtactt attatagaca
      241 tctgaaattg aaaaggcatc tttagctaaa ggaacatctg gtttatcaaa tgtaggtttt
      301 ccactttgaa ctgtcgtttc tggagttgtt gttataggta cgtatgttgc atcattttcc
      361 atagcttgag aagcttttac agcaaactct acatccacgt cgaaagttcg atttccgatc
      421 ttaacagtta caataccttt cgtactatca gtaacgttag aagtatcagg ctctgttttc
      481 catgaatact ctgcatcttc aggtaagttt ttattattcc gaattgattc tttagcatct
      541 ggtttaaatc caactaccac ggtttgttta tcaaccgctt ttggtgattc cttaataacg
      601 gttgaacctt cttctggttt atcaaaacct ggagaaacga tttggatttt taattcatct
      661 ttcgcgatta atttacttga atctacaccc gtaaattcaa attctacagt atctgaaatt
      721 ggagccccat ctttttcatt tggagcgata gttttttctg ctaatacagt accttcttta
      781 tcaacaagtt gggctttgtg acctgttccc gctaactcgt ggatgaatac tttcccctta
      841 actgttgtgt caacatcata tacttcttct aattcaggtt tcccgatata tggattcgtg
      901 tctccgctct cttctttatc gtcagggttt ccatcaccat caatatcttg caaataataa
      961 taacctgttc cataagtgtt ctggattaat tttttattcg tatccgacaa ccaagaatca
     1021 aagatgaaat cttcaccaaa tggtttattt tcttcaactt gtgctgttgc tttcatatct
     1081 tctaagattt catctaatgg cttagtcaat tgtaaaacat atcgaataac gactggacgt
     1141 ggacttgcat tagcaaaatc gataagttta gttaaatcat tattagttat tgaacctatg
     1201 ccataatttt catgaccttc ccgtcgctcg attgctaaat cagctacttt tgttccggat
     1261 tcaaacgaaa catcatatgt tactttgtca gcctgaacca tgtgcatctg tatacccgct
     1321 acatatggaa ctaatcgttc atcaattttg taattagcat accaaggcgt gccctttgcg
     1381 gaagatgaat atgagaaatt ataatttttc gttaacttat gatctaagat tatagctcca
     1441 ttagcacctg tggatcctga accatctttt gtttgagtat taggtttctc atattttgca
     1501 cttactgatc catgtttaaa ctggtcagga ttattttcag atacatctaa gctattatag
     1561 aaatcatctg aatctgttaa aaagtagccc gtactatcaa tacccggtac aattttatca
     1621 tcgtcttgat gacttaccaa gtagattcga tacattaaac gatcggtctt gagattgtct
     1681 atgcctatct ctttaaaaat ttcatctagg ctcttttcaa acgtaattac cccattagga
     1741 gcggtttgcg tatcggttgt ttctgcccca gcaaataatc catcacttgc acgaatataa
     1801 ttgaccttcc aaatatttgt aggtctaccc agcgaatcat taattcttac aaaggtccgt
     1861 ctagaagatc caattccttt ctttggatcg acctgaattt tttctacata tttagctaat
     1921 cgttcatcta attgaagacg gatttcccag tttttagttg atgctgcaat attatgtttt
     1981 ccgtaaactt caaatccaat tgtattgcct tttagtgtgt ctccagttag ttcttgagga
     2041 ctaaattgta aatccgaaaa gttataattt ttcgtataac caggattctc ctgaaaagta
     2101 ttccccgaag ctactttgtc acctacttgt acggagctta tcgctgtttc aagtgggctg
     2161 cttggagaaa tttcatcttg tgctttaact agttcagttg ttcccaagac aagaccaaca
     2221 ccaatcaaaa cagatgcaac cccaacactt aattttttga tactgtactt caatactcgt
     2281 ttctttgttt tttctagaaa tactctctta ttattcttgc taaccattat tcaaatcaac
     2341 tcccttaata attactttcc tagtaagaat aaaagataaa tctgatacgt attattcaca
     2401 gaataggaat cttactaacc ttatgttaac taatttactt agagaatttc atgaacatta
     2461 caacaaaaaa agtacatttc ttcatgtttt tttcggatat ttgtgctttt taaccattca
     2521 gcagctgaaa acatataaaa agatatgtat gtattctttc tgaaattaag ttcatttcta
     2581 tgcgatgaag catgttttca aaatattacc ctttcttaga ttaaacttca gagtattcaa
     2641 ataacggaat aaggagcctt atcccgcatt actgaatgag actgtgacat aagtaaaaag
     2701 gtgacttcaa attccttctt cggaatttga aatcaccttc tttataatta taaagtatcg
     2761 gtttcacagc atttctgaat gattcctaga atcttaaacg aatgattgga gttatcaaca
     2821 ttttttcact cgtttttagc gaaacaaaaa atgacatttg tcacagcctc attaaattat
     2881 tgattctttt tctttataat tgaattgtcc atatttaaag tgtctagtac tctacatgaa
     2941 taattaattg ctttcactca aatacttata atctattaac ttgtagttgt ttaacttttc
     3001 tgaaaaagtt agacccacgt aataatcttc ccagctttct ctttcaatta actgatccaa
     3061 tttttgataa tccataaatt catcatgtat caaaaagaat aaataacttg atattttagc
     3121 atctagctta atcagattaa ataatgtttg tttaaaattg ctaccattaa tatgactgat
     3181 agattctcta gcttcttcac ataaactttt tactttatta attactactt tgtcatattc
     3241 atttaacaca ctattattac cattacttag acgctcagat tctacgaaac aactcaaatc
     3301 agaaatttcc caaaaaaatt ttttgttaaa atccaatttc ctcaactcct ccaaactacg
     3361 taaatgatat agtctcataa taaaataaaa cctctcagct aatgttgttg aaattgtcca
     3421 ctaaacctaa ttgatattgc ttaggagata cacctgcgta ctttttgaat actctcgaaa
     3481 agtgtgaaga atctgaaaat cctaaaccta aagaaacttc actgatagta tggtttgatt
     3541 tcaacattat tttagccgta gaaatttttc gcttagagat ataattataa atcgtaatat
     3601 gcatttcatt cttaaagctt tctcttaatt tagtttcact tacagaaaaa taattagcta
     3661 tttcctttac agtaattctt ttatagatat ttaagccgat gaattgaacg acagaagaaa
     3721 ttaagggaga aagatgctct atcttagttt ttccgatttc cttagtataa taaacaatcc
     3781 cagaatccct cacttttaag acctcaggta acgatacagc taattcgttt tcttgtatca
     3841 aagcatctct actttgatac gcttctatta tatccattcc taatgttata gacgtttgtg
     3901 ctaacttttc aaaaacaatg atagaataat ttttttcaga ccgaatcgta tctccactaa
     3961 cacttggaat tattccatta ctcagattaa aaaccatgtt ttctaaattt cgaatatctc
     4021 catttttaac atattccagt attttatttt cataaagaaa cagatatatt tctggatcgt
     4081 aattttgtga taacagatta tctattttga tttgctcgat agttttactt agattttctg
     4141 tatattcaat taacggttca tggaatagat cttctatttt tccagtaaaa aaataatgaa
     4201 ctaaaatcag aatatctcga atgtctccta aagaatacaa agtcaaattt tgcaatgaat
     4261 tatagagtcg ttctctatca gccattgcaa cattcaaatt gttcattttt agtttaaaaa
     4321 aaactttatc aatattattt gctctaaatg gaccaaataa gtaatatctg gttttaaaca
     4381 tgtatagaag aaacatctca ttaaaatcac cagtaaagaa atggaaatct ttagtttttt
     4441 taatattatc agttagtaac tttttataat cataaaaaaa ataagtagtt ctatctgagc
     4501 gatactcttt tataatactg aattcggaat taaaaaccac gataggtaac tttaaacaaa
     4561 catgaagaga ctttaataag acttctttat ctgaaaacac ttttgtttct ctctttcctt
     4621 tctacatcat taaatagtat tttatacgtt atctaaaata ctattcctct gtcaaaataa
     4681 gctaacttac ttcattataa aatatccact tatcgctttc atgtatattc caccgtaaaa
     4741 agtacatttt atcaccgaga actcatcatt tttcatcatg atgaatacta tttacatata
     4801 tctagttcaa agacaataat tattatgatc cgttattatc taagcactat acagataata
     4861 ggaatttttc gtttctaaat attccaattt gggaatccaa taaaaatttt cgttcaaata
     4921 cgtgtctatt cgaactcttt tctagttgtt aattatgaag ggggaagaaa taaaaaatac
     4981 aatctataca cgaataagaa tattatccaa aaggaggttt tagaaaagat ttattatacg
     5041 taaaaagctc aagacatttt cttagccata aggacatgtt tgatatttaa gaagatatat
     5101 gaattttctt ttctaagtat aaagataact atccattatc aactaaaaaa acatttttga
     5161 aaataaacat cagcagtcct atcaatgcat gtgagcttat agaagttatt cgcagcgcag
     5221 cataattgca ttagcttctt ttcgtgtttt ttgcctcttt tccctttaaa tcttaatgga
     5281 ggaggtgtgc aatatgtcag ataacgacga acgcgtaaat gcccagttga ttcgattctt
     5341 tgaaaaggtc attttgaaca ccgctaatac ttattataaa aaacaagaag aaattcaaaa
     5401 acatgaacaa cttgatcaac tcccaccata tttgtttact aaagatacta taaaatttaa
     5461 acaaccgatt aatgttttaa atgtgactct ccttgttgaa gatataaaat tagcaaaaat
     5521 ccttcctttg ttgaaagaac ctgaacaaat ttttcttatc gaaaaattta tctttgataa
     5581 aactgataaa gaaattggaa aggttctggg gattacaaga cagggtgcga caaatttaaa
     5641 acatcgactt tacaaaaaaa ttcaaaaaat gctggtttaa tatctgcata ataactaatt
     5701 ttgtatgctt ctttgctcgt tctcctcctt cccaaagaaa tagattataa gtccatggga
     5761 agaaggtaga tttatgaatt ctttaaaaga agatttcatt ttagcaaagg ctggaaatga
     5821 agaagctgtt gaggcaattc tcaaaagatt tagctctttg attcataagc aatcctggag
     5881 aactggaaaa tatgatcaag attgttatca agaatgtatg cttgcaatat atctagctat
     5941 ctcgaaattc gaaattaaag aataactcaa ctaagggagt ctgtgacata agtaaaaaga
     6001 tagtttcaaa tttcgaacaa taaatttgaa actatcttct ttataattat aaagtatcga
     6061 ttttacagcg ttctataata attcatagaa tctaaaacga atgattttaa ttatcaacgt
     6121 tttttaattc gtttttagct taaaaataac ttttgtcaca gtctcactcc taaaattact
     6181 ttatttacgt atgaagtggg caggaggtcg aatccagaac tgggctatgg tacttcaacg
     6241 aggacttctc ctctagaatt gaaaagcatg cgatttacct tccgtaacga cggtagattt
     6301 attcaactat gtgtccaatc aaaatttgtc tgatttcaaa aatagtcaag agaattttgg
     6361 ttgttaaaaa ctcttatcta tcaacttcca cagtttagtt gacaaaccct gatactaagt
     6421 tgggctatga tacacttttc ttgactatca gttacgttac cggaaggaat gaactctatt
     6481 gagaaaaaca tatgatcgta aatttaaact aaagatttca caggatatcc ttgagaaaaa
     6541 agtaactacc aagaaaattg ctgaagaata caatatctct cgtccaacaa tttcccgatg
     6601 ggtttcagaa tatcgtcgat acgggaaaaa tgcttttgct ggacaaggaa aaagattacc
     6661 tgataaagca gatttctaca ttcttgaaca ggaaaataaa cgactaaaag aggaagacga
     6721 gtgttctacg aacacaaaga tcgatacgga tctccaggga tcactcaaaa actttacgat
     6781 gaaggaatcg aaatcaataa acgtgttgta gctgttctta tgcgtgaaat gaatttatgc
     6841 acaagaggat ttcatcgacg caaatcttct catggtagag aaaaaacaat caaagaaatg
     6901 gtaaaaaaat gttgaatcga taatttgaac agaaccaaat tgatgctgtt tgggtgatgg
     6961 atattactta cattccatgt aatgacggtc gcctctattt gtccacctat attgacttag
     7021 caactcgtat tctacgttac tatatggtag attcacacat gaaaaaagag attgtcgtcc
     7081 gtccattaca aatttattaa ggagaattgc ctacggtaat tcattccgat agaggtagcc
     7141 agcatcggtc ttttatttat caagagctgt tgaacgacca ccacatcaca cattcagtga
     7201 gccaaactgg gactcctgtt gacaatgcag taattgaagc gtttcatcga tcaatcaaat
     7261 gagaattaat cgactccaac aaatataaaa gtaaaataga gatgaaggtg ttaatccaag
     7321 attatttaga agactactac ccaaacaaaa gaatccatac aaaatttatg atgactcctt
     7381 gacaatttga agcgaagaaa ataagggatc tataatatct agtgttggtg acgccttctg
     7441 ttgccaatac tttttctttt ttctaataaa cgcaaacaga caccttaaaa tcctttagaa
     7501 taaagtcgac gaaaaccatt caaaggagtg tttcaagatg tcctattcag agtttaccaa
     7561 agagttacta gatattctag acctaaatct tatctttcat gaagatgcct ttcgcaaaga
     7621 gcgaatcaat gacgaaacat gttttgtttt tgatggcaca ttgacctatc aaccggagga
     7681 atgctttcat cgccactatc aaaatgaaca aacgatcatt aaatagggct ggaaaaaagt
     7741 atccatctta ttgaatgatg tcagtaacta caagaccatt ctgcggatta acaaacagcg
     7801 cttcaaatgt aaacactgtg gaaagacttt tttagcagaa gattcagtta gtgatcgtcg
     7861 ctgctccatt gctcgcagag tcaaacaagc cattcttgag ctattaagcg aacctctttc
     7921 tatgtctttg atcgcacgta tgaagcacat ttctccgacc actgtcattc gaatacttcg
     7981 cagccttcgg cctaaaacca tttctttgag ccagctgtta ccagaagtgg tgtgtttcga
     8041 tgaattcaaa tcagtgaaaa atgtctcggg agccatgagc tttgtcatga tggacggcaa
     8101 gacccatcaa ctgattgata ttgtggaaaa tcggcaactc aatcctttac gcgactattt
     8161 cttgcgctac cctataaaag tccgtgaaca agtgcgtcta gtggtttcag atttctatac
     8221 accctatcgc acattggtga aagagtgttt tccgaatgcc cgaatcgtcg ccgatcgctt
     8281 tcatattagc caacacattg gtcgggcttt taccaaccac cgaattcaag taatgaagac
     8341 ctttaaaaaa ggggatcgtc ggtcgaagca cttaaagaaa tactggaaac tacttcaaaa
     8401 gaatgcgtgg gaattgaaag gtcagcatcg ctactggcgt ccgtcatttc gagatcatct
     8461 gacagaagca gagatagtcg atcggctatt atcttatgat gattccttaa agcgaggcta
     8521 cgaagtctac caggattttc tttccgttat cagaagacaa gatgttcctg aattcgtcgc
     8581 gctcctaaaa gaagactaca aggagttgcc agagcactac caaccagtgt tcacgacctt
     8641 caagaaatac caaacagaaa tcaaacgagc gttgcgcgtt ccctattcca acggccctat
     8701 agaatgtttg aataaccata tcaaagtact aaaacgaatt gcctatggct atagaaactt
     8761 tcaaaactac cgagaacgaa tctttttata tcgaggaaaa tattttaaga aaactaagaa
     8821 tactacccaa ctgactaaag ccagaacaac aacacggcta gacaagatag ctgtctagcc
     8881 gtgtgagtat ctcgattatt ctattgaatt tcttcaccaa cactcattga cgaagagcca
     8941 aaataagtaa tctaaccgac tgttaactaa accattgcag gtcccgttaa agatacttgt
     9001 gcctgttgtc accgcttctt tttcttgtcc acaagcgctt aacacactta ataaagcccc
     9061 tgctattatt aataataata tctttttctt attaaaaacc tcctcatcta tttccagatt
     9121 agtaaatgta gtaatctgtg ctttcttttt tctcaatact aataactaac ttatggggta
     9181 aacaaatact cgtttgaccg ggttttgaga tccatccagt tctaaccgcg atttgatcag
     9241 gactattatc ttctttaact cgaattcttc catctttaat ctcaacaata ttatattgtc
     9301 ccttcgcagg atgataattc acgagtttat gattgatctt atccaaatcg aagcgatcca
     9361 tttccttgcc atcaattcga acgatggcat atttgatagc atcttcagtt gtttcattct
     9421 ccttttctat agagaataca aataagggaa taaaagaggt aataatcaaa atgccaataa
     9481 ttatgacatc gcctatcttg acaccagctt ttcttaaaaa tttcattaac gatatctggc
     9541 taaacatatt agactttttc catggaaatg gtgaaatttt tcggaaatta tctgcattaa
     9601 gagaatcagt taaacaaccc tcaagttgtt ccttaataca ttgttgatcc atcttcatac
     9661 caataaaaac tagtttatta atgcgttcac caaacaacgg atgccaggct tccttcaatt
     9721 cgggattttt ttgtataatc atttgacact caattttagg taaactagct acccaataat
     9781 ttaatgattc aatactttta tagctacccg atgtttcaaa gatcgtcgaa aaatcactat
     9841 gttgggcaaa ccaaagaaac ccttttgctc ttgtaatatt gccaggaaaa tttttatccg
     9901 taagatgggc aaatttttgt gcgtcaagga gtaaccgatt tcgatagata aaacttgaga
     9961 taccatattc ttctgtttca ggaatatgat tttgatagcc aagctctaac tctttgaacc
    10021 agcccactga ataggaagtc tcatctatat taaaaagatt tgtatttaga attttcgata
    10081 agtctacttc acctttaatt gtcctaatta ttttggcatt ggactgtaac ttagcaatta
    10141 gaccgttaat tttgtaaatc gtcttggttg acactaagtc actattattt aaaagtaata
    10201 tgttacaaca ctcgaattga tcaattaaca agccacgaat atcctgttct tcttcaacta
    10261 cattaccttc agcttttctt tcctgaatct tttcacccgt ttcgaaatta tcccaaaaac
    10321 gttttacatc cactactata ataatggcac caatctctaa tcgttgggtc aaatcaatgt
    10381 ctaaagggtt tttagctaat ataattgctt gaataattgg aattggtttg ctgattcctg
    10441 aagcttcaat aacaatttga ttcaagtcag aaaattgcac taattgatct agttcaacaa
    10501 tcaaatcttc gcgtaatgta caacaaatgc atccattcgg catcgaaaca agtttttctc
    10561 cagttctttt aaaacctttc ttgtcgacta ataccccatc aacatttact tcccctatgt
    10621 catttacaat gacagcaatt tcctttccgt gatcaccgta cagaatatga tttagaagta
    10681 tcgtttttcc tgaaccaaga tagccagtta agattgtaat aggtattttt ttcataggga
    10741 acctctttct ataccttgaa tttacacttt aagtgcaaca cataaaaatg agtcataatc
    10801 gatatccaac tagtataagt ttgtcgagaa cactcctaga aggaaaataa ttatgagcca
    10861 gtatcgtcat cttactatac tcgaacgaga aagaatcttt ctgcttcacg aagaaggatt
    10921 ttctattagt ataattggca acgacattca gcatagcccg tttactattt tacatgaact
    10981 gagaagaaac aagaaaaaaa ctattcacct tccaaagcgg aaaaaaatta tgcttatcga
    11041 agaaaaaaat gcggacgtta tcacattcta aatgatccgt gagtttggtc aattgttcgt
    11101 catttatttg tcgattttca gtggtcgcca gaggaaatct cgaatcgttt gaagcatgaa
    11161 catatggact tttcaattag ttttatcacg atctaacgtg caatttgcaa tgatcttttc
    11221 gatacagaac ccctctcaca cggcaataaa ggcctgatcc gttcattgca ccatcgagga
    11281 aaaacaagac atacaaaaaa tcatgtcgag tctcgtggaa agatttgcct tactcattcg
    11341 atccatggcc gtccaaaatc cgcagatgat agaagtgatt ttggtcattg gaaagccgat
    11401 attgtagctg gcaaaactgg tggtacttgt ttagtgactt tgacagacag aaaatcatgc
    11461 ttccttttag caggaaagaa ggtccccaga aagaaagccg cttatgtgag cgagaaaatg
    11521 attgaacttt taagcagtat tccaaatgag gcggtcaaaa cgatcactcc agatagagga
    11581 aaagaattct ccaatcattt cgcagttaca gaagcattga ataatatgcc cttttatttt
    11641 ccagatcctc atgcccttgg caacaatgaa caaattaaaa tacgaataga ctcattcgag
    11701 aatacttgcc aaaatcgaaa gagatagcta cggtagataa ctcaacgata aatcagatga
    11761 ttgaaaaact gaataacaga cctagaaagt gtttagattg gagaacacct tatgaagtct
    11821 tctttgataa agtgttgcgc ttgatttgac aattcaagac ataataaaaa gcagatcaaa
    11881 tccaaataag ggaaaaatga tctactctgg tattatcaat taattggcca agctattatg
    11941 ccgttttgct aaacgtctac ttcttccagt attgaccttg ataaaacaac aatcaggatc
    12001 ccgttttaat actctatgaa ctgtgtcaat actaacatgt aaagttgcag caatatcagc
    12061 taatgtactc ccatttaatc tcatttgctt tgcaaatcga taacgccgat aagcatcaat
    12121 attcttggaa tccatagaca ataatacttt tcttaccatg tatttcctcc aaaaattgaa
    12181 ttttaatgag ccatcatttc ttgagcaatt tcatgtttag acaatgaagc tggatagaaa
    12241 gtaggccaat tatgcaattc attatagagt ttttcttgac tttctccacc aaagaaaata
    12301 tggaaatgct ctgccttact tggtgcaatt ccatgatcac taaattgaat atatttaaaa
    12361 cgaccagcac ctgcatcatc agtttcaaaa ttaaaacgaa caccacggtt tcctttttca
    12421 taattcaaaa ttttgtatcc aacatatttg tatgtgtatt gatgatgttc accgttgact
    12481 acaaaatcaa tggtgttgtc tttaatgttg atagtatcaa tatctgtctt atagccagta
    12541 gtataataat ctttgtactc ggcagctgtc atgtctttat tgatttttgc tttgtaatcg
    12601 aaaacttcat ccaaaattcc atcttttaac aacggataaa cagattgcca ttcgcctgta
    12661 taatcactca attcgcgatc cttcacatcg gcatctttaa agtacccatt agcaactgtc
    12721 ttttcatcct tcgcttcttt ttctggaact acctcttcac cagcaaccat agttgttttt
    12781 tctaacgctt ttagattgtc ttccattact gaaacataat cttcaccatt atccatttgt
    12841 tcttttgtaa gactttcaag aggattcagt acttccaatt ttatcccagc ttcgttggcc
    12901 aaagtttttg caattttatc attagcattc ttttcaaagt aaatataatt gatcttattt
    12961 tttttaacat actcttttaa ttcagctaat cgaccagaag atggctcttc ttcaggactt
    13021 agtccagcaa taggaacttg tttcaatcca taatccaaag ctaaatatcc aaaggctgcg
    13081 tgttgcgtca caaaactttt ttgtttcgct tctttaagac tagtggtata gtcagcatcc
    13141 aaccgtttca gtttagtcaa atacttttca gcatttgtct caaatacttt tgcttttttc
    13201 ggatacaatt taactaactg atccttgata tttgaaactt ccttaattgc cattttgggt
    13261 gaaacccacg tatgaggatc tagttcatga tggtgatctt cttctccgtg atcatgatct
    13321 tcttcttcac tacctggcaa taaaatcatg tcttttgttc cttctactac attaggccca
    13381 gctttcttcc aactttcttt agcttttggt acccatgatt ccatgttttc gttatgatat
    13441 acaaaaacat cagcatcatg agcttttgcc atatccttag ctgagggctc atagtcatga
    13501 ggttctgatc ccgctggaac cattaaatcc acgttcgctt catcgccgac gatgtttttg
    13561 gtgaaatcat acattggata gaatgttgtt acaatttcta attttccatc tttatcattc
    13621 gatacttttg catcattagt gctggagcaa gctcccaata atcctagagc tgctatccca
    13681 ataagtccta cactgatttt cttcattctt tttccttcct taattatgct aatttcttca
    13741 ttttatttcg tttatgttct ttgataattt ttaatgccct ttttctagtt ttaatattcg
    13801 ggcttttaag tcgtcgatat gcactagata tatccgtttt ctccattaga aattaccccc
    13861 aatcactact tatcattatt tgctttccgc cagtaattta tcaaaactct gtttgatcct
    13921 ttcttcatcc aacatttttc cgattagaat aatagtggtt tggtcttttt gtcgagtggt
    13981 gtattgaaaa ttaacctgtt cgtttacctc ttgcatggca actataaaat cctgctcttg
    14041 taaagcaatc aatcctttaa aacgatacag gctcccttgg ttggttaaaa tcagccagtc
    14101 aatccattgg agtaaaaaat ctttttttat gtcttgatct gaagttaaga gaattgattt
    14161 aaactcatgt acttgatggt gttgatgata gtatttgcca ttatagtgat tttctgatga
    14221 atcactttca aaaactaagg gatgattaaa ttttttcaaa ttataaaaat cctttttttg
    14281 aatcgtttca ctatgtgtga acattcgaat atcggataaa gggttaatac ttttgatttc
    14341 tctctgtaat ttttttagtg cagataaatt caagttttgt tttctagaca caaaaatgcg
    14401 atctgccatg acaagttgct taagggcttg tggttctctt tcaataagtt caaaactgtc
    14461 actatcaata acagtcaata aactatcgat atatactctt cctcttagtt gaggcgctgt
    14521 taaaagtgtt tgaatgattg gttggggatc tgctatacct gtagtttcaa tgatgatttg
    14581 tgaaattggt tgttgatgtt cttctattgt ttccagtaaa gaaatcaata ttgctaataa
    14641 atcactgcga agactgcaac acatacatcc attatttagt tgtaacaccc gttcctcgct
    14701 atgaactaat aatttgtgat caatcccaac ttcaccaaac tcattttcaa ttataataat
    14761 ttcttccctg gggtagggtg agacttgcaa ggcttgattg attagcgttg tttttccagc
    14821 ccctaaaaac ccagaaacga ttgtaactgg tatgcccatt ttgtcacctt tttaccactt
    14881 agctatttca cttctttaaa aattgcccgt ctgcgcaatt ttggcgaata cttttttaat
    14941 tctaaccgtt cagggttatt ccgtttattt ttgctggtga gatacagacg ttctccagtt
    15001 tcgacacatt ccaaaataat attttgacgc ataaatcttc ctccttcaat acttatcgat
    15061 cttcaagata tgcttgaatt tgttgtgcat cttcaaaagt taactcgcca gattccaatt
    15121 gtgaaactaa attttctttc atatcaacag gtatctccca ataaccatcg atacattgaa
    15181 ataactcctc gtcatactct tcaaaaattg gatagattct taaaaaatca tcaaatgata
    15241 agccttggtc ctcatagtaa tctttgacta atccattttc aattgcctgt tgggtcggta
    15301 aacccgtttc agtaataatt cctctctcta ccatcgaacg ataaaaagtg catttatcta
    15361 gcgattgctg ggtcgtttca agataatact ttaatccttc ttcaactaaa ggtgggtaaa
    15421 taatttccat tttgattccc tcctaaaagt tatatattaa actattttga agctccttta
    15481 attactttct ttccattata gtaccctttt aaagatacat gatggctacg tctataatca
    15541 ccattcgctt cgtcaaatga aatttctggt tttactacag tttgatgagt tcttcttaac
    15601 cgtttcttcg ccttagatgt ttttcttgct ggtactgcca tgatatttcc tccttttacc
    15661 aacttgcttt ttttactcca ggaatcaacc cttgatgggc aagttctcta aacttaatac
    15721 gggacatacc gaactttcgc atataccctc ttggacgacc atccgtctga tcacgaagcc
    15781 tcagacgatt cggatttgaa tctcttggca atttagcgag agcggtgcga tctcctgcgg
    15841 cttttaattc ctgacgttta tctgcatact tttcaatcat cgccatttgt ttctttgctt
    15901 tagcaatttt cgactttttt gccatatacc tttatactcc ttttattttg atttagacac
    15961 ctcaaatcgt aatcgttacg ttttgacact gatactttac caacaagagt tgctcttgtc
    16021 aacaataaat aacatgaaat aaaactcata tgaatagata actatttgaa aacgaattta
    16081 tcggtacata gagataatca aatcatttaa aagaatatgc agtttaggct ctgaaaaata
    16141 agaattcact tttattagtc caatcaaaca caaataccgt tttaagtagc ttttcctcta
    16201 cttaaaacgg caatatgaaa gaaactataa ctttttattc aatcttttat gtttaactgg
    16261 tttatcgcca attttttaaa actttgatta ttccttatat tataagaata gacattaagt
    16321 gaactaattc aatcatactg attctttcgt gtattcaaaa ttagatgctg tttaataaaa
    16381 ttattctttt tgaaaaagaa ttataactat atcccaaaaa ttgtaggtta atttaaagcc
    16441 tatttcatca tcgtgattga gcttcttttt catagacgaa tttctcagat agtttagttt
    16501 tctttatgag atttttgtat atttctgacc ttcgatacaa ctcattatga gtaccttgat
    16561 caactagttt tccttgatcc atcactacaa ttttatttac cttttcaata gacttcaagc
    16621 gatgcgatat aattagtact gtcttatctt gtattaaacg atttaaactt tcctgaatac
    16681 gtttttcatt ttccgcatct aaactggcag taatttcatc taaaattaaa attggcgcat
    16741 ttttcaaaaa agcccgtgct atggataggc gttgtcgctc tcctccagaa agtgaacttc
    16801 cgttttctcc gaccaatgta tgataaccgt caggtagttt ttcaataaag tcttcgcagt
    16861 tagctaaacg agctgctttt ttcacttcct catctgacgc ttgactattt ccaatacgta
    16921 tattttccaa aatacttgta ttaaacaaag ttacctcttg aaaaacaata gcgattttgc
    16981 taaacaaaga agctggagat acacgtttaa tatcataccc atcaattaaa atacagcctt
    17041 catcataatc atacagtcta gacactaatt tcaagatact agttttcccg gaaccactag
    17101 cacctactaa cgcagtcact tctccttgtt tagccgtaaa agagatatga tctaaaattg
    17161 gggtattgtt atcatatgag aaagagacat ctcgcaactc aatgtcaaaa gatttcagag
    17221 gactatctga tccctcttgg atactggttt ccttcatagc tctaattcgc tgtattttag
    17281 gagctaaata aaatatttca agcactgctt ctttcataga atcgaaggaa tcctttattt
    17341 ttattgcggc tagtaagtaa ccaacgacgt agagtatagt cacttcaccc gttaacagta
    17401 agtgaacacc tactagaatg actactgcta aactaacata tgagaaaata gaggataagg
    17461 ccatgactga aaaagtactt aattctacct ttaaatgaat cctttcactc tcttccattt
    17521 ttttgaaaag tctgtcttga acttttttag atagattaaa gctattaatc tcttgctgca
    17581 attctatagt ttcttgaaat tcttccgagt tttctctcaa agtatcgtaa tatttagtat
    17641 tggctttcgt ttgggatttc tttgataaca agattaagac aaaactaaat aacgttggca
    17701 aaataacagc taatcccatt ttgacattac caaccaaaag catcactgaa ataaaaggga
    17761 aaaacagagc cataccgccg gctttaggta ttgcatgact catcgcatgc tcaatacctt
    17821 caacgtcaga catgatagtt tgagataaat ctgataaatt atgttttgaa aaataggata
    17881 atggtaaatt tgacaaatcg tctgcaattt gcactcttaa atgcgcactt tctttataag
    17941 tactattata taagttttca tactccctat ctaacaacca atacatgaaa agcaaagtaa
    18001 caaacgatac ggcaaaataa agccaacggg gctttgtatt ttctaaaact aattcgtcta
    18061 tcagcatcat tataatgaat gctggtacca tattaatgca gtatacaaaa aaactagaaa
    18121 tagaagcttt agttaaagct tctgcgccct gatcacttaa agcaaatttg tttttataaa
    18181 aacttttcat tgtcaagcct ccaatcattt gcattctcat aattagtgac caattgttta
    18241 tacacttgat gtttagccat taattcatta tgatttccac gttctactat tttcccttct
    18301 gacaagacaa gaatttcatc tacagattta atgctggata atcgatgagc tatcataata
    18361 actgtttttt ctttcatcag atgttgaaaa gccttttgta gttcatactc attatctgga
    18421 tcaatagatg cactggcttc atccataata acaatctttg catcttttaa aattgctctg
    18481 gcaatagcta tacgttgttt ttctcctcct gacagataaa ctcctttact accaattaag
    18541 gtatgctctc tttcgggaaa tttttctaaa atcgattcgc aaccggctaa tcttagcgcg
    18601 tcaaatactt tacttgctgg cgcttgagga tttgctatag aaacgttatc gtaaatactc
    18661 tgattgaata gtttcgtatc ttgaaagaca aaagcaattg tgttaataat tgtgtctttt
    18721 gaatagtgat ttaaaggctt accaccaatt ttaatctgtc ccttatccac attgtagaaa
    18781 cctgaaatta gtttagctat cgtactcttt ccgcttcctg attttcctac taatgcataa
    18841 attctttttt gttctaaaac taagttgaaa ttttctaaaa cacactcttc tttgtatgaa
    18901 aagctgacat tttcaaatgc aatgtcacaa tttttaatct gtgtctcgtt cccatatttt
    18961 agttggtctt gcttcatttc taaataaagg gagtctagtg tttcgactgc atatcttgct
    19021 tcaaacaagt gcatacttac atacattatt ctcatgaaag aaacaaaaat aattccactt
    19081 aaaaaaaaca acatcaacaa gtcaacagct aatatcttgg gagtggtaag agaagttata
    19141 aaaaaggtta taggaactat caaaatgcaa actatgccaa aaaatagcca ttgaaaaaga
    19201 acaaaaggtg ttttcccact caaagaatac ttatatgcaa acttagcata atcgttaatt
    19261 gctttattca aggctttaaa tgatgttact ttagcaccaa atatctttat aacttgaatt
    19321 ccgcggatat attctaccgt ttcagagctt aacacatcta acgattcttg atatttttga
    19381 ataaaatttg tattctctgt cattttcttt aacaagaata caccaattac taacatggcg
    19441 attagaacca atccaatttt aaagttaatg aaaaagccta aggcaactga taaaacaggt
    19501 gttactatgg cttgagcact atctggaatc aagtgagcaa ttgccatatg tgttttagcc
    19561 gcgttgtcat caattgtctt tcgaatatat cccgaagaat ttaaatcaaa aaaacgaaaa
    19621 cttgcttctg ttaaaccgct aattcccttt tttctcaaat tagtctctaa gcgaaaccca
    19681 aggatatgag aaaataagcc agaaaaaata taaaataaag ctcctaaagt taaccaagca
    19741 acagtttgaa ccgcataact cttagctaaa tattcatctc ctacaataat tagagactga
    19801 agaaatttgt aaatactgta atatccatag actgttaata cgacagaaaa atcagaaaat
    19861 aaagtggcta accatccgta gtatttcatt ttagggacat aactaaataa ttttttgtat
    19921 actttcattt tttcctcccc cgcattcaat ttcttctctt attcgtttac aactgttaat
    19981 gctttccgta atagcgtaaa ttagagatgt acaaacagat aaaaggtaaa ctacgttcta
    20041 ttttttgtat ttttttaaga cttttcttcc aatcaataca ccaatcatag ataaacttgc
    20101 tacaactaac actgaaatga ttccccatat acctaccgca tagtggatca ttgcatccat
    20161 tgttgcagca gattgtcctt tatctatcca atcttgacga aaacgatctg taaagaacca
    20221 tataggaatc cactgtccgg cagcactgcc taattgcatt agagcccaag acgcaacttg
    20281 aggaattgct cgatcatatc caaatacaga tagaataata tcagctaaga tcgccatact
    20341 aatcgaactg ataaaccaag gtaagtacgc cccgcccatt aacgtaaaaa ataacaataa
    20401 aacaattgtg taaatagtaa aaattccttt tctagggtag ttatagctaa tataaacaaa
    20461 tatgattcca gataataatc caaaaatccc gggggatatg ctgtgaccaa acgccccacc
    20521 aatactacta accattattg aaaaaaagta aattactagg gaaataactg tagctaaacc
    20581 aataaaaata taatcttttg ttttcatata tattctcctc aattctattt cgttatgtca
    20641 ttaaaaatct gttctatcaa agttgaatct tctactctaa gttttatatc tttttttatt
    20701 ccaccatttt ttaaataaat aattctattg catgttttat aaagaaattc cggatcatga
    20761 gtagctataa ctactgcacc cttttctttt aagtctttaa taaggtcagc aatcctttcc
    20821 atattaatat aatccaaccc acttgtaggt tcatcaaata gaaataaatt agtttttgac
    20881 aatgaagcta tagaaaccaa taatctttgt ttttctccac cggataaatc aaacggtaat
    20941 tgatctttca ttttataaag ttccattttt tttaaaattt tttcttgctg atctttacta
    21001 actatttcat tccccagggc taactcgctc ctcactgatt ctgtgaaaaa ttggtaatcc
    21061 atttcttgca ttactaaaaa cggcgatgac aaattttttt tattttcgat tatctttcct
    21121 ttggtagggc gaataatctt catgagtatt cttagtaagg ttgttttccc cacaccgttt
    21181 ttccctacca aaccaataac atctccaact ttgacatcaa aatttatgtc ttttagaata
    21241 ttttcataag taatttcttc aacttttaat acatctgcac ttaccttttc gatataggga
    21301 acttcaatcg aactattaaa aatgtcaaat ttccttaatg cgttattgtt ttcagttttt
    21361 aacaactgaa tagttgtagt ttttacagtt ctatttttaa caaatagaac ttgatcaatt
    21421 aattctttca aatagtaaaa acgatgttca gctataacaa tagtaaatcc tttatttttt
    21481 aaatcacaaa gtaagtcagc aagtttctta gtcgctttga agtccaaatt tgaagacggt
    21541 tcatccaata taattaattt agagtttagc gataaactac atccaataga aattttctgc
    21601 cgttcaccac ttgatagcga aaaaatgttt ttatctaata tatttgaaag atctaataat
    21661 tcagctaatt cattgattct tttatccata tgctcttttg taaatccaaa gttttccatc
    21721 gaaaatacta actcactcgt tgtatttgtt gtaaagaatt gtcctctagg atcttgactt
    21781 acgtagccaa tattttttga tatactttct tgtgttaagg attgtagcga gttattttca
    21841 aataaaattt ccccaaccaa ttttccgtca taaagtcttg gaataagtcc attcattaac
    21901 tttaatagtg tggatttccc actcccagaa gaaccagtaa tcaatgtaag actgcctttt
    21961 tttattgaaa aattaaggtc aacaagcgct tgttccttaa catccttata tgaaaaagaa
    22021 acattgttaa attcaaacaa ttctttcacc tcaaatcaaa atacttaaga aaaaaatagt
    22081 aacggaaaac aggatgatat agtctaataa gctcatgttt gttttatagt aagaacttct
    22141 tttcacagga gattctatcc cctttgttat tgcattagcg gtcatttctt cagcaatcat
    22201 agttgcacgt ataagaacgg gaactaacag aaattccaaa tattgcagag gctgaaaaaa
    22261 agacaagcga atgtttctca tttttaaaga ttctttaatc attcttattt cagaacgata
    22321 agtcggaaag aatctgatca ctactgtaat acttaacatt atttttttcg gtaaatgtat
    22381 tttttctaaa gaggataata attcattgct agtatagaca ctaaccaaca accatgagat
    22441 cattacgacc ggcaacattc gaaatacaat atataaggat gtcgcaaaaa atatagtaaa
    22501 aaactctatc ttgatagcat caataatttt cattactaaa aacagaactg aataaatcaa
    22561 gatgaaataa atacatgtct ttattttacg aaacatcaat actaaaactg tagcaataat
    22621 gaaacacccc acttgaaata tatttccctt tcctaaaaaa ataatgaccg gaaaaaaaat
    22681 atttaaagta atcaaggtta acggattgat ttttgacact ctttcacctc caaaaaataa
    22741 gatcgcactg ttatcttaag ctgataaaaa tgcaccgtta ttcagataac agtgcgatct
    22801 tatcaaaaag cataactgag aacaattctc aatgcaagct ttttttaatt aactcagtaa
    22861 ttcaatccac ccaggaacag aaaattgata caatcttctg gttaatagca tagtcttttc
    22921 ttttgaatag ctatgcttca atatatcata gaatgtagcg tagaatgagt aaatgtagaa
    22981 gtggatttct tcttcattaa agactaaatt ttgattgatc attccgatag tctttaactt
    23041 atctagacaa cagactgtct ttttcgtcac aaatgatgta attttttcaa caatatcttg
    23101 atatttggtt ccagctgatt ggaataaaat caaatcgaat atacgtttat tctcaaaaat
    23161 ataattaata aatggatcta attcattgaa gttctctctc caacttttct ctatatctat
    23221 attttctaag tttaagaggt atttggtaaa ctcttcatta tacatattaa taagcgcatt
    23281 aatatgcggc tgaataattt cttcaaataa cgcttcctta gaagtaaaat gtttataaaa
    23341 agcacccgta gttacgcctg cggtcaggca cagttgcctt atcttagttt gctgaaatcc
    23401 ttctttttca aaatggctta gtccactttc tattaacttt tggtgagtta taatataatc
    23461 tctggtttct atgggtactt cctcctaata agatgaatta actttattat cttacacagg
    23521 acttgaagtt tcaatcgtta acgtttatta ctgaactcat tccttagagc taaactaatg
    23581 agaaagagca gaataactga tacaaaaagc aatcctacaa gaattaatag actcatctaa
    23641 atcattcacc ttttctaaaa taatccgaga aagatttaaa aaaattatat ccagctatta
    23701 ggataagtcc tatcataatc actccaatag ccattttctt atcctcccta aaaataaagt
    23761 cttttactta aaaccttttt tgtaatcgtc aataaatttt ttccctttat cagttaattg
    23821 aaatcctata tctaaatagt cctcatatct aagtttagcc agcatctcac ttacagatgc
    23881 tggactaaca cttagaactt ttgctaaatc attatttttt aatttctttt ttctttttga
    23941 taattcctga attgctagta aataaattag tatagtagtc gttttaattt gtaccatacc
    24001 taccctccaa attatttcga aaggccttca gcaattttat ccaggttcca tttcatcatc
    24061 gcatagtaac tatcaccatc ttgtcctttt tctgcaattg aatcagtaaa aatcgttgaa
    24121 tagataggaa tattggtatc ttttgatact gttttcattg gtctatcatc cacactgctt
    24181 tctacgaata aggagggaac ttttgttgtg cgtaattttt caactaagtg ttttatttga
    24241 tctggtgttc cttcttcttc agtgttgatt tcccaaatgt aagcagaagg cacattatac
    24301 gctttcgaga aatatttaaa gcatccttca cttgtaacaa tcattttttt atcattcgga
    24361 attgaagcaa atttagattt agcttctttg tctagagaat ccaatttttc aatatactta
    24421 tctagatttt ctttatagaa ttttttatta tcaggatctt tttccgctaa ctgtttttca
    24481 atatttttag cgtaaataat accgttttct aaatttaacc aagcatgagg atcttccttc
    24541 cctttctcac tctgaccctc taagtaaata acatctatgc catcacttgc tgcaaaatag
    24601 tctttgtttt cctctttgtt cgcattttta actaattttg taaaccaagc atttcctcca
    24661 gtttccaagt taacaccgtt ataaaaaatc aaatctgctt ttgaagtttt ttgaacatct
    24721 tcaggcaaag gttcatattc gtggggatct ttcccaatag gtacgatact gtgtaaatca
    24781 attttatctt ttgctatatt ttcggtaata tctgctaaaa tcgaattagt aactactact
    24841 tttaattttt cgttcgaagc cactttatct ttgtctttac tatttattga acatgccccg
    24901 aatataaaaa gagcaatcaa aatccccaga cttcccagta ctgctttcca ttttctcatc
    24961 ataacgatct ctccttcttt cttaaaaatt tttgttttgg tgagattaga aaactaatta
    25021 caaataagaa tgccgctgtt aaaacaatac ttgatcctgc tgctatgtta aaactataac
    25081 caataaacaa tccaagcaat gatgaacttg ctccgactgt tgcagaaata aatatcatag
    25141 ttttcaagct atttgcatat aaatatgctg tagctgctgg tgtaattaac attgcaacaa
    25201 ttaatatagt tcccacactt tgcatagctg ttactgctac taaagttaat agaaccatca
    25261 atagataatg ataaaaactg acattcatcc ctattgcttt tgccattaat ggatcaaaag
    25321 aagtgattaa taattcttta aaaaatagaa ctactataac caacactaaa accgaaacgc
    25381 caattgtaat ccacttatca atatcttgta cagctaaaat atttccaaat aaaatatgaa
    25441 ataaatccgt tgagctattt gcaactccta taaggataac tcctagtgct aaaaaagaac
    25501 tgaaagtaat accaattgct gtatctcctt ttattacact attgcttttt ataaaagtaa
    25561 taatgataga agctaataga ccaaatacaa tcgcaccaat aaaaaaatta atacctaaaa
    25621 tataagaaat tgctactcct ggcaaaacag catgagaaat agcatcaccc ataagagaca
    25681 ttcctcttaa aataataaaa caacctactg ttccagaaac aatccctata actacagatg
    25741 taattagagc attctgtaaa aagtgaaagt catacagacc attaataaaa ttttgaagca
    25801 tattattccc cctctccaat aaatatagta tctccatagg ctttttttaa attttcttca
    25861 ttaaatacag attctacact tccgtgagca attagatttc gattcaaaag aataatatta
    25921 tcaaaatact tctttacctt gcttaaatca tgatgcacaa ttagcactgt ttttccctga
    25981 tgtttcaatt tttttaacgt atccataatt attcgttcac taactaagtc tatccctaca
    26041 aatggttcat ctaaaaatat gaaatccgca ttttgagcaa gacatcttgc taaaagtaca
    26101 cgttgaaatt gtcctccaga taattctcct atttgatgat tagaatattt tcccatatcg
    26161 accttttcca aagcctttga aactctttgc cattctgcat ttttaattct ttgaaaaact
    26221 ttcattccgg catatgttcc catagataca cattctttta cttttattgg aaaagtaaaa
    26281 tcaatatcag ctttttgctc tacatatgca atcttcacca gttttttatt gatatcttca
    26341 ttattaatgg agacctctcc ctgatgaggg ataatattta acattgcttt aagcaatgtg
    26401 gattttccag caccatttgg accaataata cctgttaaag caccttcttg tatttttaaa
    26461 gaaatctcgt tcaatgctaa aaaatcgtta taacaaacat taagcttttt cacttctaac
    26521 ataactttct ccttctaaat gataatgatt atcacgatca tatggtatac aaaaattata
    26581 ttttagtcaa ccctaaattt tatagtttag atttttttct gttgctgaag attagaatga
    26641 caaaactatt tgaaactacg cgtatagtaa gtagctttca aaatatataa aaaaggagcg
    26701 ttctcaaatg agaacatgct cctaaaacta ctttattggc gtatggaaaa attatacttg
    26761 aagtggatag cgggttgaat aagttgataa gcatcaaaac atttataaaa attattcaag
    26821 actatgtctg ttccatatac aaatatgaaa atcagtaaac tccatttaac ttttttcgta
    26881 gtgtgtcttt ttatacatgt ttatcgttat taatagtgaa taggaaaaaa actatttttg
    26941 atcattgaca attaaataca atttttgaat aacgatccct gctattcgag ctagaaactc
    27001 aagtacgcca tgacctgatt agcgacaaat acttagagat ttctttttgt tctgggaaaa
    27061 caaaatgcca tgacaatagc agcaaataat gatacttccg taaggctcgc cgtaaactgg
    27121 ggagaggtga aattcctatg tgcttaccca aagcaattca aaaatttcat aactactatt
    27181 ttaggagatg attttataga atccagagtc tacctgaata aaaaacaaac ctgtgcattt
    27241 ctaggaatcg ataataatac tctagataag tggattcgta tatataattt cccagtaata
    27301 agagttggtg gtgtagttcg ctttgacgta gaagatatta aagactttat gaatacttga
    27361 aattttcttc tcgccgcata tactaaaatt agtgaaatat actgccttac tttttttaag
    27421 gagtgaggat tttgcctaca aagctttcaa atgggaaata taaaactaat ctgagatatc
    27481 caaaaaggtt taaagaaata acaggaattg catcagaaaa gtatcaaaaa acatttccaa
    27541 ataggcaatt ggcgattaaa gccgaaaatg atatgaagaa gaaaatagaa aaagttttga
    27601 gagaggagaa tgcaaactca ttagaattaa aaggaaaaat aacgtttaaa aaattttacg
    27661 aatctaaatg gcttcctaga tatgaattag gtcaaacaat tagatcaaac aggcctccta
    27721 gtgatataac cattagtaat acaaaagata tatttcggtt gcatatttta cctatgtttg
    27781 gtgaatacgc aatgaattat ctaaatatca atactgagat aatatcagat gaattaacca
    27841 aaaaatcgaa agaatatgca aatataaaaa tcataaaagg atatgttcgt tccatgttcg
    27901 atattgcaga aatactaaat tatatcgaat ttaatcgaac tactaaaatt attcaaagta
    27961 tcactgcacc taaaaaaaat gctttagaag aaaaaagaat acaagaaggt aagcaagcac
    28021 tatcatcaaa agaacttact aattggatag aagcagtaaa tgatgatttt aataatcatt
    28081 tacttacttt tcatgattac acacttttta tgattaccct gtatcttggt gatagaaaaa
    28141 gtgagactta cgctttgcaa tggaaatata ttgattttga aaaacaaacg gtccgtctta
    28201 aacatacttt agataaatat caaagaaaaa agtttacaaa aggtcgaaaa gataccgtca
    28261 ttcaagtacc agaagttgta atgacattgc taagtgaatg gaaatcggta caagctgatc
    28321 aattgttgaa attaaaaatt aagcaaacgt tagatcagta tctctttact tatactaaac
    28381 catctggaga agtaaattgt cctgttcatg ccgattacct aaactatcga atcaattcaa
    28441 ttaaaagaag gcatcctgac ttagttcatt tatctccaca caaactccgt catacttatg
    28501 caactatagc tagacaaggt ggagcagata tgaatcaaat ttcaaatgct ttaacacact
    28561 cagatatttc tacaacaaag atatatgtga acacaccaga tatagttgat aaggctgttt
    28621 ttgaagcttt tcagagagga ttgaataagt gtgattgata tgtgttctta aatgtgttct
    28681 taaaaacaaa agaagcactt tccaaataat tgaaaagtgc cagaaacgtt gatatataaa
    28741 ggatattaac gttttgagaa ttgtgaagct ttacgtgctt tcttaagacc tggtttttta
    28801 cgttcgacca tacgtgcgtc acgagtaagt aagccagcac gtttaagagc taaacggaag
    28861 tcaggatcaa cttctagcaa tgcacgagcg ataccatgac ggatagctcc tgattgtcca
    28921 gcgtatcctc cgccgtttac gttaacaaat acgtcatatg cgccttttgt ttcagtaaca
    28981 gcgaaaggtt gattgattac ttcacgcaag tcagcatgtg gaatgtattc ttcaacatct
    29041 tttttattta cagtaatttt gccagttcct ggtactagac gtacgcgagc aactgcgttt
    29101 ttacgacggc ctgtgccgat atattgaact tgtgccaatg aaattccctc ctattagatt
    29161 aagtttgtga tgtctaaaac ttctggttgt tgtgctgcat gtggatgttc tgctccaccg
    29221 tatacgttca attttgtaaa ttgtttgcgg cctaaagtgt ttttaggaag catacctttt
    29281 acagaagttt cgatcaaacg acgagaattt ttagcacgca attcgccagc agtgattgat
    29341 ttcaatcctc ctgggtagtt gctgtgacgg taataaattt tgtcagtcgc ttttttacct
    29401 gttaatttca ctttgtctgc attgatgacg atgacgaaat cgccagtatc caaatgaggt
    29461 gtgaaagttg gtttattttt accacgtagt acagatgcaa caactgttga aagacgtccc
    29521 aatggaacat cagttgcgtc tactacatac catttacgtt ctacttcgcc tggtttggcc
    29581 atatatgttg tacgcacgtt attttcctcc aatttaagtt ctgatgtttg acatacactt
    29641 cgagtttccg gggctctttg tggggcaaac aataccattt aacatattac ccgctaatct
    29701 agtcaatgtc aacgtttttc tgcttgattg aaaaatttat atgaaacttt acttcttttc
    29761 tttcttttat ataaaagggt cgtttcctgt caaaatgaaa aacaaaaaga ggctgtgaca
    29821 aaagtcttgt cacaacccct tattttgaat aaacggtgtt ctcctgccaa ctcctcggtc
    29881 acaagtcaca atatccataa aacataagaa gctgtttttt aaaattgttt cttgtgactc
    29941 ggagctgaac ggcaggctta caacctcttg gtaaacggtg ttcaatcagc tgaccctcgg
    30001 tattagctca aaaaacggca aaatatgagg aactattttg acgtttgttt ctctaatact
    30061 caggtcaaaa cgctgatttc acaacctctt tttcggtcaa gttcaacaac agtttttacg
    30121 cgtcgatctc tggcgctttg cccaaatgag cttggatcat ccagatacgt ttttctgtgg
    30181 ctgttttgaa ttcgataaag atatcttgtg ttggatcgtc gccttcttct ccagaaactt
    30241 cgattccttt ttggtaaaga tctgctagat aacgatagcc tgcaacaagt gtttccaaac
    30301 gttctggaat agtacgatcc cagcggccaa tttcatcagg gatttttgtg ttatctgcaa
    30361 attcacgcaa tgtagaataa ggtgaaccgt ctaatgtgat caagcgttcg gatacttcat
    30421 ctaactgagc gttcaaatca tccatgaact catccatcat tgggtgcaat gtaaggaaac
    30481 ctggtcctct catgtaccaa tgtgtttggt gaacaacaac agacatttgg cttagatctg
    30541 caactaattg atttaatact tctttggttt gttggaattt catctttctt gcctcctaac
    30601 attttcttac acttaaaata atagtagact ttcaatgaaa agtacaacaa aatcatttac
    30661 ctgagaacga ttttcagttc gcttttttat ccgtaaagcc aatcattttt cagaatcagc
    30721 taattcttct cgcagttgag caaattgctg ataagtctgt gctaaatgct tttgtgtcga
    30781 aacaaataat ggatagattt tctgatattt tttatgatca gtttcttgta ctccaacttg
    30841 ctctttcaat tctatcaatt cctgtgcttc actgatactt tggatctttc cgatgcttct
    30901 ccagcctaaa atcacagctc ctaatgcgga tgcttctgtg acagtaggga aaacaagcgg
    30961 gtaacccagt acatcagcca tcatctgacg aaaaatcgga gattgagcaa acccgcctgt
    31021 agcacggatc tctgtgagct gattttcctg gcaaactcct tttaaaatcc gataaaggtt
    31081 gagacagatc ccttctagaa tcgccttcat catttctttt tctgtatgtt gccgctgtaa
    31141 accgataaaa ctgccaaacg catctgcgtc ccaaagcggt gctcgctcac caagtaaata
    31201 gggatgaaaa atcagaccat tggcacccgc tggcacaaaa gcgatagccg aaagcagtgc
    31261 atcatatgga ttttctcctt tttctttagc agattgaacg acttcctgta aaaatgtatg
    31321 ccctgcccaa tcaaagatgc cagcaccatt gctagtcgct cctcccacta cccaatgttt
    31381 ctgatccaga acataacaaa acgtctccat ttctggatgg aactgaggct gagtagtaat
    31441 aaaacgaagt gctccgctcg ttcctacggt caaagcggcg atcgtatcac caaaagcacc
    31501 taaccctaga ttagaaagcg gcccgtctgc ccctcccaaa acaaatgata tatcatttgg
    31561 caaacctagt tctgctgctg tttttgatgg tagacctgtt acttgatagg tggaaggaaa
    31621 gacttgcggc aattgctcta ttcgaatgtt caagtagtca agcacttctt ctgcccattg
    31681 gaattcatgg atatcaaaat atccagttcc tgaagctgtt ccgtagtcgc tgatcagttc
    31741 gccaaacaat ctataaaaga tatagtcttt gataccgaca aaataagcag tttttttgaa
    31801 taattcaggt tggctgtttt gcagccactt gattttgttc aatggtgtca ttggatgaat
    31861 cggcgtccca gtctgccgat aaaattcttt gccaagcacg gtatatttca gtttttctgc
    31921 ttcgtccgct gctcggttat ctgcccaagt gatcattcga gataacggtg ttttctcttc
    31981 atccaacaat atcaggccat gcatcgcaga ggagaaggag acaaattgaa tgattgtgtc
    32041 tgaaggcaac tgtttaatta cttcttttat aacggtgcag acaccttgaa agatcaattc
    32101 ctgatcttgt tctgccatcc cttgtgtttc ttggatcaaa gggtagcgaa aataagcgga
    32161 tgctgcttct tgggcttcat ctgtgaaagc aactgctttg gtttgtgtgg ttccgatatc
    32221 taatccgatt gaaacgttca ttttttcacc tcaaatttta tgtatgtaca aaaatttagt
    32281 ttaagcttgc gtatcttggt tttgaaaagg gggagatggc gtgttacttt attttatcat
    32341 tggttgctgt atcggatcat ttttatgttt aaccgcccag cggattccgt taggtcactc
    32401 tattatttat cctagatctc attgtgtcaa atgctgtcgt tcgctttctt ggtatgaatt
    32461 gattccgatt ctctcgatca tcgtccaacg atttcgctgc cgctattgca ggtgtcggtt
    32521 gcccttctac tatttgttgg cagaagcctt atgtggtggt ctttttgcct ggttctttac
    32581 tttttcttcc gcaagaaatt tttcgacgtt catatggatg ctttcggctt tgctattttc
    32641 gttgatggat ttattttact tcatggtcca ttctcacacg ctattctgtt cttgggcaat
    32701 tttatggatt ttttggttgc aggccggcgt cttccaatgg caaagtgtgc tgttaacgtt
    32761 tatcgtaggc ggtgtgtgcc ttcgctatgg tcaatcctat ctcggagctg gcgatactct
    32821 gttgatgctt tcttggagtg gtggcttgtc tctagaagag ttgcttcaga tcttgtttct
    32881 tgctagtctg tttggaatat ccgttttttc tgtttacttt atctgtcata aaaaaaagtt
    32941 ggaaaagctg cctttcattc cttttttgag cagtgcgttg ctgattgtcc ttcatcttag
    33001 gtattgaaaa aaggttgtga caaacgactt gtcacaacct ctgatatata gtgttctctt
    33061 accaaatcct tgtgacttgg agctaggcga caggttcaca acctctccac taaatggtgt
    33121 tcaatcagct gaccctcagt attagctcaa aatgctggtt ttacaacctc tgatatacgg
    33181 tgttccataa gtagcttttt cggcttctta tttcttgacg ccccaatgtc gacgaaggaa
    33241 acctgcacgt ccagaacctt ctcgataaag attgtaatgg agcttgtttt tcttgtaata
    33301 atcctgatgg taatcttctg caggataaaa ttcgcttctt ggttcgattt ttgtcacgat
    33361 tggcttatcg aatcgcccgc tgtcttgcaa tgcttgtttt gaacgctctg caatatttcg
    33421 ttcttcttca tcattatagt agatcactgg acgataagaa tcaccgcgat cagcgaactg
    33481 tcctaatgcg tcagtcggat cggtttgctg ccaatagatt tccaccaact gatcataaga
    33541 aataacttct ggatcatatt cgatctctac tgcttctgta tgccctgttg tgcctgttgt
    33601 tacttgttca taagttggat ttggtacatg cccgccagta taaccggatg tcacagaaat
    33661 gatccctggc tgctcttcaa atggtttgac catacaccaa aagcatccgc ctgcgaaaac
    33721 tgcttttttt gtcatataaa atcccccttt tttctcatca taccttgatt tccaaaagga
    33781 ggataacgtt ttgcttgtga cagaaaaaac ggaaactatt atatacgtga tacggcttct
    33841 gataaatgcc aaaacgaacg tacttgatca aaaacggtta aatcaggaat cacatattca
    33901 gcagaaggaa gatttatgtt ttcacctatt cccaatacat gcatgttacc agccaaagct
    33961 gcttgacaac cagcttctga atcttcaatg accaagcatg catttggcgg tacattcaat
    34021 tgctgtgctc ctttgagaaa aacttctgga tcaggttttg cttttgatac ttgcgtgccg
    34081 tcaataagga catcaaaata acttgtcaaa ttcgtttttt ctaaaatgag gcgtgcattt
    34141 ttgcttgctg atcccaatcc gatcttgatg tttgtttttt tcaagtactc aagaacagct
    34201 attgcaccag gcaaaacgga tgtttcatcc attttttgaa tcgcttgaag atatagattg
    34261 tttttttgct cagcaaaggc tgatttctct ttttctgaga atttctgttc catttttcca
    34321 aatgacagca atcgctctag tgactcggtt ctggatattc ctttcagttg ctcgttttct
    34381 ttctcagtga atggaatgga cagctggtta gctaaaacca gccacgcttc gtaatgataa
    34441 cgagctgtgt ctacaagaac gccatctaaa tcgaatagtg ctgctttgat tttcatcgat
    34501 tacctccttg aaaatgaacg acttgaagta aagatgcgat gtttttagct gtgcgatgaa
    34561 gattatcagt ggcttgctgt aaagcttctt gtaaaggcac agctgcagga aggatcggaa
    34621 aaacggccga aatgccaaca tctgctgctt tttcgcttcc tttaccaaca cttccgcaaa
    34681 tagctatcac aggaacgccc tctggtactc ttctagcaat cccaactggc gcttttcctt
    34741 ttagactttg tccatctaga cgtccttcgc ctacgattac gaggtctgct tgctgtaccc
    34801 gtttatcgaa ctccagtaaa tccaatacgt agtcgatgcc agagactatt ttccctgaag
    34861 caaatgctaa cagtcctgca cccattccac caccagcact actgcccgat gcctcgatta
    34921 cttgaggggc aaatctcata taaaaatcat gcatggcttg gtcagccact gctaattcat
    34981 tttctttcaa gcctttttgt ggtccgaaaa caaaagaagc gccttctttt ccgcataaaa
    35041 gattagtaac atcagtaatg acagtgattt tggctttaat cagctcaata ggcacgttcg
    35101 ttttatcaac tgtagcaatt ttacctagat tttctcccag tgcttctact ttttgattat
    35161 cttgatcgta aaaagcataa cctagacctt ctgccatgcc gatgccgcca tcgttggtac
    35221 tacttccgcc aacgccgatg atgatgtgtc gaacaccttg ttgcaacaat tgtcgtatca
    35281 gttctcctac tcctcgcgtg gataacctaa gtggctgttg ttggtttagt gggacatctt
    35341 tcaatccgac gatttctgcc atttcaaaaa tcgcagtttg accgtctgaa gcgtactgga
    35401 tttctttgtt tttgccaaat gcattagtaa cgactgctgt ttgccgcttc aaccttaaac
    35461 tgtctgctaa tgatgaaacc gttccttctc ctccatcgcc tataggtagc agatcatatt
    35521 cagcctgaac aaaaacttct tgaaaacctg attgaatggc ttgtgctgcc tctaaggctg
    35581 tcagactttc tttgaaagaa tctggcgcaa tcagaatacg cattattttc ccctccgttc
    35641 caagatcagt tctttttcca gctggtattg gtctccattg acaaaaatag gtaatgtttc
    35701 tttcgtctct ttttttatta ctatttgttt ttttgtcaaa acaaatagca acctgtgatt
    35761 tttccaaata aaaggaaaag aaattttttc ccatgctgaa ggaagtcttg gagaaataga
    35821 aagagttcca ttcgttactg taatacctga aaaaccaaat ataactgcta gccatagtgc
    35881 tcctaatgaa gcagcatgaa ttccgtcatc tgatgaatgc ggatctggtc ctaaatcaat
    35941 caggcacgct tcttggaata aatgatacgc ccattccatt tcttggatac ggcaagcctc
    36001 tatggcgtga atcgctttac tcaacgatga gtcgtggatt gttttgtttt catagtaatg
    36061 caaattctta gaaacgattg gttgagaaaa atactcaggt aataagtata acagcatgac
    36121 aagatctgct tgcttgctga cttggagttc atttacttcg ctacgggcat aatcaagtaa
    36181 aatagactgg ctgccaggac gttctttgta agtggtcaaa tcaataactg gcttactgag
    36241 atacgtgtca ccttgcggaa tcagctgttc tttgttaggc actggcaaat ataacttatc
    36301 taaaaaattt tgacattctt tcaaaaaaag cggatcgcca gcttgatatt taacagctaa
    36361 ggccacatta taatgcgcca gatagttcgt atatgcatta ttgtcgatat attctgtgta
    36421 ttcatctgga ccaatgactc tgtgtatctc taaatgatca tcgactttta cagctctgct
    36481 cagccaaaaa gctgctgttt catgaatgag cgtttttccc tttgtttcta aaaacgattg
    36541 atcctctgtt gcttggacat actcttgaac ggcataagca aggtctgcac tgatatgatg
    36601 ttctgcggca gctgaagcaa cttcttgtct tgttccggtt ttgatattca atgcagcaaa
    36661 tttgggtgtc tcttcctgac cagtgtgtgc gctttcccat gggaaaagtg caccttgata
    36721 gtgataatct cttgcttttt gccgtgcgcc ttctaatcga tcataacggt acagcagcaa
    36781 attctttgct acttcaggaa actgatataa aaagaaaggc aggataaaaa tttccgtatc
    36841 ccagaaaaca tgccctttat aaccttcgcc agttagtccc ttcgccccta cactaacact
    36901 tggatcattg cggggagtca taatctgtaa atggtaagca gcgaagtcca tcgctaactg
    36961 atcgaaagaa gaatcgcctt ggatcgttat ccgatgctga tgccaaaaat ctgtccaata
    37021 agacatcgac tgctctaaaa tttctgtata actaacgctt ttctgggctt gggcaatact
    37081 tttcttaaac gggtctgttt gctgaagaga ggtagagagc acgatgatct tctccagcgt
    37141 aaaggacgta ttttttctga tcttttctga aaaggaagcg gtgatccggc gattttttgc
    37201 ttggaataca cctgctttat tgaatttagc tgcaatccca atatcaattt tactttctgt
    37261 tgtctggtag gatgcactga tcaaatcgtc accaaatact cgcagttctt tttcaaccaa
    37321 ctgctgtgta ccaaaattgg tttgctgtcc atcgataccc gttttcacat ctacttggca
    37381 gtcttcggtc aacggcttga tgaccacttt cagggctgcc tgatggagat tattttgatc
    37441 agcaacacga caagtaatga cttccacttt ttttccttga gcagtttcaa tgagcgcata
    37501 gcgtttaagc tctcccattt ctaaatctag tgcccgctcg tatgcaagaa ctttcatcgt
    37561 ctcaagagaa aaatgttcac cgtcgatttt tatttcccat ctgatgacat ctgggagatt
    37621 cactaactcg gctgattctg ctcctaaagg tcggttatat acaccagctg caaacattcc
    37681 ccttacttga ttccgatagt cttcctcctg gcttcctctg ataccaaaaa atccatttcc
    37741 aatggtcatc tgactcgcat acttattgat atactctaaa tcaaactgtt tttcttctac
    37801 tttcataagg taataacttc tcctgtttct gccgaacgat ataaattttc caccagattc
    37861 tggatgacat atccttgcca gccatctgca atcatctgag tctggtcacc gagcgcccga
    37921 ttcacaaaat gagccatact tagttcatgt gggtcattaa ctggcgtggt cttttgtaag
    37981 gaaaccagct ttccatctac atcttcgaat agttcgcctg gatacagatt agcacctgcc
    38041 tgatcgccac aaaaagccac attcagtttg tcttctctga tattcaaagc aaacgaagta
    38101 ttcagttgga tgatcttgcc gttttctaat tccagtgtgc caaaaattgc atcttctact
    38161 gtgaatttgc ttggatccca tttcccgaat ttccctgaat tttttttcgt accaattttt
    38221 tggaagctgt acgcccgaac gctttttact ttaggaaatc cagtaatata catcgctgta
    38281 tcaagcatgt gaatgccata atcgatcaaa ggcccgcctc cttgaagttc tttgtcgata
    38341 aacgttcccc agcctggaac accagaccga cgaagcgcat tcgcttctac gtaataaata
    38401 tccccgagaa catcaagatg attcttgatc attgttgctt cgtcagaaaa acgatgctgg
    38461 aatccataag ccaaaatctg cccgttttta tcggctgtct ctgccatctt tcttgcttga
    38521 tcagctgtca tagctggtgg tttctcgcac atcactgaag cattagcttc gagggcagcc
    38581 aatacatgtt cgaagtgaaa gcgattgggt gtacagacac tcacgatatc gggagaaatc
    38641 tcattcagca tttgtgtaac tgatgtatac gcatgagaaa atcctgtacg tcggcaaaag
    38701 tcttctgctc gctggctgac tggatcaacc acagcggcca attctaagac atctgatctt
    38761 ttttgataat aagcagcatg tactttttct gctacttgtc cagcgcctat gattgctact
    38821 ttcttcattt atttctccct cctttgctta tttacttatt gttattcttt ctctattctt
    38881 tctctaaatc atttaaatga cgcgctgttt ccagacagtt tttcaagtat tgcaatgatt
    38941 cctgataaat tttcacttca ttttctcctc gcaaacgaca ttcatatacc atataacctt
    39001 catactcatt ttgaagtagc gtttgaaaat ggcgagtaaa atcaattgcg ccagatcctg
    39061 gttggtagcg atgattatct gctaaatgga tatgacccac atactctttt tgcgtagtca
    39121 atgcttttga aatatcatct tcttcaatat tcatatgata aaaatcagcg atgatctgca
    39181 catgtttcaa ttgattagag tcaatgtaat gacgcgcatc cgctaacaaa ttgatcatat
    39241 ggtcttggta tcggttcaaa ggctccaaat aaataaccgt acctgtttct tcggctactt
    39301 tatctaaata acgaagtgat tcgctgactg ctttatagtc tccttctttg cttcggggtg
    39361 aaaccatcgg cggtaatcga taagtgaaca ttccccaagc tgctgggata acgattcctt
    39421 tgcctccaac ctcgcttagt gcacgcaaaa tctcagcaat ttgacgtaca ccattaagac
    39481 gccgttcttc gataaagtca ccgatccacc catcgtagcc gttacaagct gtcactactg
    39541 ggatccctgt ttctttgatt gcctgtttga ctgtgtcgat attttctatt aacaacttac
    39601 cgtcgatttc gtattcttca aatccacagt ctttgataaa tctaaatttt tctaaaatgt
    39661 ctcttgggaa aaatgcttga tcttgcgtac cgaatttcat tgttctcctc ctcggacttg
    39721 aacgcccatt ttgatacttt cttctgggtg ctggtctaca taacgcatgt aagcttctgc
    39781 gctttctgca aatggcacaa ctggatcaat gatttcttca caatccaagt aaccgttcat
    39841 caataattcc caacatgtgt cctcgattcg tttacggttc catcttgggt aatctgggtt
    39901 tggttcacta gatgctcgag caaagacgat ttttgcatta ttgaaatgtg cttcgcgacc
    39961 aagattaaac ccagctggaa aaggtttagc aaaggcaaca taagaaatga tcccgccata
    40021 gccgatccct cttaaagaag cttgtaatgc ggcagcactg ccactcgttt caataactga
    40081 atctactcca cgtttatctg tcaattcctt tagacgaaaa ccgacatctg ctttcatagg
    40141 atctagcgtg taatcggcac cgtatttttc tgctaattct ctacgctgcg ctatgggatc
    40201 gatcccaacg atggtagtag cacctgcttt tttagctaat tgaatcgcaa tttgcccgat
    40261 agcgcctaaa ccgaagattg ctacagcatc acctgctcga acatgtgctt cccggatacc
    40321 acctaaagcg aattgagcag gatcgtaaca tactgcattt ttccattgat ccaaccgatc
    40381 aagtttacgt agtttataat tatcaacacc gtttgtaatc agcgtttcac gaatgggtcc
    40441 ataagtgcag actaactctc ctttttgata ctctgtcacc aaactgcccg tttcttcgat
    40501 cgtaccgaca atcatatttc ctaattgaaa ttcgccaaat accacaccgc gttggcttcc
    40561 ttcttctctt ggcaagaata ggcgctattc ttctgaaaat tcttcatcga taaatggact
    40621 taatcctcta aagtcgacaa tttctgttcc tggttttgga gtagcgaaaa ttactcggat
    40681 acgtacttcg ttcttttcga tctcacggtc ttcgtaatct ttgaatccgg ctattcttgg
    40741 ttctaatgca actaattttt tcatcttttc tttcctcttt cttttctttt tatcctttta
    40801 cgccgccttc gactaaatca cctttaataa atcgttcaga taacgcatac ataatgatga
    40861 ctggtaaagc ggtcaccaat gaagcggcca tcattcgtcc ccaaatgtag tctggtgtac
    40921 tgaataatgt gttcaaaccg attggtaaag taaatttttc ggaggtcgac aggaaaatcg
    40981 aagcaaataa ataatcattc cacgaaacca taaagcaata aacgaagaca gaaatgattc
    41041 cagaaatagc caatggtata atgatccgaa taatgatctg gatccggcta agaccatcga
    41101 tcattgctgc ttcttcaata tcagtcggaa tcgtgtcaaa ataacttttt agcatgaata
    41161 tcgcagtagg aagtgtttga acgaccatcg tgataatcag tgctgtattg gtatcataca
    41221 aacctagacc ggaaatgatt ttaaataatg gaacaacgat caaaataccg gaaaacatat
    41281 aaacggtgta aaagctagca ttgattttcg agcgagcttt gaagcgtagt tttgacaaag
    41341 cgtatgcccc gctgatccca atcactactg cagttacgga ggctatcaag gagatcacta
    41401 aactattttt gaaatacatg atgaatggaa aaatctcagc attgaaaata tcctgataat
    41461 gttcaaaagt ccattctttc ggaaaaatag tttgtgtcgt tgcaattgct tcttgtgaat
    41521 ccttgaatga tgtcatcagc atgatcaaaa atggaaacaa attgacagct aatagcaaca
    41581 aaatcgtcgc gtaaaataag attttcctgc tctttttatt tttcatttca agtccacctt
    41641 ctttcgtgag agcaagacga ccgctgcaat aatgatgaac aatagaatcg atatagctgc
    41701 tgcttttcca agatcattga acgcaaaggc tgtctgatac aaataaacgc ctaagatatt
    41761 gactttattc gtcagtagat agacatctgt aaacatatag aacatccaga tagatcgtaa
    41821 aacaatcaca gttgctagta ctggtttgat tgccggcagt gtcacgatct tgaacttctg
    41881 ccaagcattt gcaccgtcca tttcagctgc ttcataaagc gttttgtcga ctgtttgcaa
    41941 aatagccaaa aatgaaataa acgcatacgg atagtatctc cagatagcaa acaaaacgac
    42001 cataaagaag ctagcaactg gctggtcgaa ccacagcggt gcttcgttga aaagctgcaa
    42061 cctatctact aacagatcat tgacgattcc ataactatta ttgaacatat atttccaagc
    42121 aaaaatcaaa gaaatagatg gcgtaacata acttaataaa atcagtgaac gcaccgtttt
    42181 cctaaatctg aacttgcggt taagcaaaat agctacggct aatcctaaag ctgtactgcc
    42241 tgctacaact aagaatgtgt aagcaactgt taaacctaaa gaacgataaa attcactatc
    42301 acttaaaatt tcaagataat tgcttaatcc gataaaaacg gcgtctgagt taggattcag
    42361 cggcatatcg aaaaaactga tctgaatatt ggaaagcatt ggaatcagca ctaaaacagc
    42421 taataaaagc atgcttggtg ctaaaagtcc catggctaat tttaagtcag aatgtttcct
    42481 tggacgattc attgaaacct ccccctgata atctgccaat agctatctac ttttttcgaa
    42541 caccattggc agaacttctt gttatttcgt atttttttgt gcgtcagcta aagcttgatc
    42601 gacatcttcg tttccgacag ttacttggtt cactgctttt ccgatcacac ctgagcttgt
    42661 gatatctccc attttcgtga aattcttttc cccgactagt ccaaagactt gtacttcatc
    42721 aaaagcacta gcaatctcag atggcagctc gccaaaagac ttgatgactt cattttcttt
    42781 gtaaccatcc agttcgacta cttgtttatt cactggttga gcaccaccag gagacatcaa
    42841 gacccacttt tccatgtttt tcggttgaga taagaaagct gtgaatgctt cagcagcctc
    42901 tttttgtttc tcgtctagac cagaagaaat cgtcaatcca gatactgtgc catagacagc
    42961 ttgatctttt tgtgttggga tagcaaaacc gatattttct gagttccccg cttcataaac
    43021 agaaggcaaa atgtaagttg aatagattgc cattggtgct gttccattca tgaaagcatc
    43081 tttgatttct gtcacatcat tagagcctgg catcgtgtat tgggataagt tttgataaaa
    43141 cgacaatgct tctctcatct tttccgtatc gatcgttacc tcgccttcat catccaaaac
    43201 atttgctcca tttgacaaag caaattgaga gaacgcttgc tcactcattg ttccttcagc
    43261 agtaggcata gcaattccat attgtttatt ctctttatct gtgaaatgtt gagcaatttt
    43321 taaaatatca tcccaatttt ctggttctga aaaaccagct tctgataatt tttctttgtc
    43381 ataccaaata ccttgaaccc agccgctaat tggtgcagca atatagcttt ttccatcttc
    43441 tgaacgaaca aggtttttgg ctccgtcata ataattatct tctccagctt cctcgataac
    43501 gttttggact gccgtctgat caatcagttc atctttatcc atcactttag caaaatcctg
    43561 actgacttcc attacttctg gtaatttacc ggaacgagct aacgtaacga tttttgtatt
    43621 gaacgctgat tcttctaccg gcacttgctt gattttgatg tctggatttt ctttttcaaa
    43681 atcagcaacc agttcattga tcacacttaa tcgttcctgt tcgacagaag agtgcatgaa
    43741 ttgaatcgtt gtctgttgtg attcgttaga gctttgactt tcaccacaag cagtaagaag
    43801 aaatccagta gctagcagac aggtagtaac aataattttt ttcatttttt tccacctctt
    43861 attttattat tttcagccac atatattcat acggctggaa tatcaacttt cgttcttgac
    43921 tgcaatggat aatttgtcca gaaaacaggt ctaggtaatc tccttttggt aaaagataac
    43981 ctgctgattg attggaaaaa ttatggataa ctaagacttt ctcttccttc gcttcgcgaa
    44041 taaaactgat aaaagaatct gctgagtcca gtaagtaaat caaactattc ggatggaagg
    44101 ctttttcttt ttttcgaata gatagcatct gggtcaattc accatatact gctgttctta
    44161 atggatctgt ctgcaactct ttctcaatat ctgctaacaa aaatttttgc cgattgattt
    44221 ttcgattctc tcctgttttt tctacgcctt tgtaatcatt tcgacttccc agcacacttt
    44281 gaatataaat tgccggcacg cctggtaacg ttaccaaaaa tgaatgagca gctaaaaagc
    44341 gtttgcttct ccattccgtc gtatctgttg gagaacttaa cgcatctaga tacgtagcgt
    44401 ttatctcata tggactggtc gttccatctg ggtttttctt gtagtttact cgggtaccct
    44461 ctttcttcag ctgttccact aattcaagga tcgttttttc cggcagaata cctcgtaccg
    44521 gattcaatcc gataccgtca tgggaggcta aaaaattaaa aaaagttgtt tttttcgatg
    44581 cgaaatcgat ggtttttaac cattctttca acttacttgt attacccgaa cgaatcgctt
    44641 gaagggtcaa aggtggtagc gaaaactgat agaccatctg tgcttcattc tcgccattcc
    44701 caaaataact gatattatct ttgtgtggca catttgtctc agtgatcaat accgttcctg
    44761 gagctgcttc atcagcgatt gcacggaata attggatgat tttatgcgtt tctggcaggt
    44821 gtatacaaga agttcctagt tctttccata aaaatcccac agcgtccaag cgaataaatg
    44881 aagcgccttt ttctaagtaa aacaaaagaa tatcgatcat tttcaataaa acttctggat
    44941 ttttaaaatt caagtctact tgatcttcgc taaaagtcgt ccatacgtgt ttttctttcc
    45001 cgtttttgtc aatgaacgtt gtaagtaacg ggctggtcct tggtctagtc acgctgcttg
    45061 tatctgtatc cagtggcaaa tcaataaaaa aatctttgta cgtatcattc aagtttaaat
    45121 attcctgaaa ccaagtactt tcggcagaca tatgattgca gacaaagtcg aacattaacc
    45181 gtgtttcgct tctcatttct tctatatctt cccatgtgcc caaacggtcg ttgattgcct
    45241 gataatttac aacggagaaa ccatcatcag atgtatatgg gaaaaatggc aagaaatgta
    45301 caactctaaa tgtatctgcc aaatactttt gataaaattt cttaaatgta cgcaaagttg
    45361 gttgctgctc ttcaaaaaat tgatccccat aagtaatcaa gaaaatatct tcttcgtccc
    45421 aatgcagttt gcctgcctgg cctttcttct gctgataaac actgactttt tgttcaatca
    45481 tagaggcggt tttctcagac aaatctgagt cgcgataaat cgcttgtaaa agttttgtat
    45541 acatcggatt cccctttctt ttttgggagc gttcccaacg atttgatcat attatggaaa
    45601 acgcttactg tcaatagcat ttttttaaat aattttgata tacacaaaaa tacaaataag
    45661 aaagcttatg tatcaataat taatagcttc ttaaaaaaat atggtctctc atgatcatgc
    45721 aagctattcc taaattttca aaatcataga caaaaaagaa tgtctattgt actatggaat
    45781 tattctaaaa cgctcccaaa aaggaggtgc atataaaatt gaaacctact atttatgaca
    45841 ttgcgaaaaa agctaatgtc tcaaaatcaa ctgtctccag agtattaaat aaccagccaa
    45901 atatctctga taaagcaaaa gcaagtgtac ttcaagcaat caaagaattg aattatgaac
    45961 cgagcaaaat tgcaagagga ctgtcaggaa atggttttga cgcgattcta gcattatctc
    46021 atcgtacttc tcatacgacc tatggcaatc cttttttttc agatgttatt caatccattt
    46081 ctgccgtttc tgaacaaaat aacttcgact tgattctaca aacggcaaaa acaccagaag
    46141 aagagctaga aaaatgcgcg aaaaagatcc aagaaaaaat gatccgagga attattattt
    46201 taagctctac gatggatgaa acacttcttt ttgaattgga tcaatacaat attcctattg
    46261 tggtaatcgg aaaagtcgga aacgactaca cgaacatcta ctcagtggac acggataatt
    46321 tccaggatag ttacgatttg gtggaaacac tgatcaagaa tggacaccgt catatcggct
    46381 gtctccatgc tccgacagaa gtttatgtat ccaatgatcg tctcaatggt taccgtcaat
    46441 gcttatttga tcaccaccta gatatccgta atgaatggat tatagacggc ggctttcgct
    46501 tagaagatag catggcagca atgaatgatt taatgaagct acgagaaaga ccaactgcga
    46561 ttttttctac cgatgcatta aaatcattga gtatttacaa agtggcagaa caatctggaa
    46621 agcagatacc tgatgatctt tcgatcgcag gattcagtga tcccttattg tcctccctat
    46681 tttcgccaca gttgactcgg atagacattc cgacaaatca gttaggaatc aaagccacag
    46741 aacttttatt ccaactaatc caccaccaat accctgaaga aaaaagaatc attctttcaa
    46801 ccgagattac tctcacagat tcgatccaac aacaagaaat gtagaacaga attataaaag
    46861 aacagaaaca ctgaggataa gtcagttact ctgttctttt ttcaatcact catccctcgt
    46921 taccccctcc cggtatttta gcgaattttt cttattttcc atctgtttta gatagctgtg
    46981 gataactata atgtttgtgt taaactattt tttccacagg gaagaaaaaa ctatttttaa
    47041 ccacgttgtg tataagtttt tatagttcgt ttttttaaac acatttaccc ttatttcaat
    47101 ccatgttatt tggggatact tatctctaaa acataaatag aataacagac atgtctactg
    47161 gttttgtttt attcgaggaa ttattcaata atagctagca aaatattaaa aataaccgct
    47221 ctatcttccc atcaatttat tttgcattca aaaaatgatc tatctttact tttgttgatt
    47281 gacttctctt ggaagatgat cgttccgata ccttaattgg atacgaaccg atgttgttaa
    47341 gatcctttcc cacttttctt ctagttagac aaattatttt agacaaacca aaaaagaggt
    47401 tgtgacaata atttgtcaca acctcttttt taaaatatct attttgtttg attgttcatt
    47461 gcgtcttctg cagccatttg cgcttcaata tctgaaatac tgtagacatt ttcgcttgct
    47521 acaccgactt cttttggttc catgtcacga taacgttgca taccagtacc agctgggatg
    47581 atcttaccta taataacatt ttctttcaaa ccaagaagag gatctttctt accgcggatc
    47641 gcagcatccg tcaagacacg agttgtttct tggaatgatg cagcagataa gaaactattt
    47701 gtttctaatg atgcttttgt gatacctagt aagacaggtc gagaagttgc aggaacgcct
    47761 cctgagacta gcgtattgta gttttgatct ttaaagtctg cgatgtctaa taatgtacct
    47821 ggtaagatat ctgtatcacc tggatccatt acacgaactt tacgcagcat ttgacgaacc
    47881 attacttcga tatgcttgtc gccgatttct accccttgca tacggtaaac acgttgtact
    47941 tcacgaagca agtagttttc aacagataat acatcgcgaa cttgcaacaa ttgttttgga
    48001 tcgattgatc cttctgtcaa tggtgcacca cggtggatca tatcgccttc tgctactttc
    48061 atacgtgctg tataaggaac agtatacgta cgtgtatctg tttttccttt gattgttact
    48121 tctttggtac gtgttgcagg atcttctgag atatcgatga catcccctgt tacttctgtg
    48181 atcactgctt gccctttcgg attacgtgct tcaaagattt cttggacacg aggaagacct
    48241 tgagtgatat cgtctccggc aaccccacct gtatggaatg tacgcatcgt caactgagta
    48301 ccaggttcac cgattgattg agcggcgatc gtaccaactg cttctccgac ttcaacgtca
    48361 gagccagttg caaggttgcg tccgtaacaa tgtttgcaga caccatgttt tgtattacat
    48421 gtgaagacag aacggattgt cactgtttcg acacctgcat caacgatttg ttttgcgatg
    48481 tcttcggaaa tcaattggtt tcctgcaatg atcaattcat ttgtttcagg atgacgtact
    48541 tctttacggg tgtaacgtcc cactaaacga tcttctaatg attcgatgat ttcatttccc
    48601 tcgcggatgg cttggatttc aagacctcgg tcagtaccgc aatcttcttc acggatgatt
    48661 acatcttggg ccacgtcaac cagacgacga gtcaagtaac ctgaatcggc agtcttcaag
    48721 gctgtatcgg tcatcccttt acgagccccg tgagttgaga taaacatttc caagacggat
    48781 agtccttcac ggaagttcga aatgattggc aattccatga ttcgaccatt aggagcggcc
    48841 atcaaaccac gcattccggc aagctgtgta aagttggaaa tgttaccacg agctccagaa
    48901 tcagacatca tgaagattgg atttttcgct tccaaacctt ccatcagttt ttgttggatg
    48961 ctgtcttttg cagcattcca aacagcaatg acacgttcat aacgttcgtc atctgtgatc
    49021 agaccacgac ggaattgttt tgtaatagtt tcaacttgtt tatgggcatt ttcaatgatt
    49081 tcttgttttt cattcagtac actgatgtca gcgatcccta ctgtgatacc ggcatgtgtc
    49141 gaatgtttgt accctaagtc tttcatacgg tcaagcatct tagaagtttc tgttactttg
    49201 aatcgtttga agacttctgc gatgatgttt cctaagtttt tcttcttgaa cggtaatact
    49261 aattcttgct ctttgatatg tgcaggaata tcagtaccag cttcaacaaa gtatttgtcc
    49321 ggtgtttgga cggtcaagtt gaagtctgtt ggttcattca gataagggaa ttcaggaggc
    49381 atgatctcgt tgaagatgat cttaccaact gttgtgatca tcgtacgttc tttttgccat
    49441 tcagtaaatg gtttttcacc taatgagtta gggttcacac cgatacgtga atgtaaatga
    49501 acatatccgt tgcgccatgc gataacggct tcgttttgat ctctgaagac cattccttcg
    49561 ccttcgcgtc cttcttcttc cattgtcaag tagtagttac ctagaaccat atcttgggaa
    49621 ggagtaacaa ctggtttacc atctttaggg ttcaagatgt tttgagcagc taacatcaac
    49681 atacgtgctt ctgcttgtgc ttcttcattc aatggaacgt ggacagccat ttggtctcca
    49741 tcgaaatcgg cattataagc ttcacataca agtggatgca aacggattgc gcgtccttgt
    49801 actaaaactg gttcgaatgc ttggatacca agtcggtgaa gcgtaggtgc ccggttcagc
    49861 aatactgggt gttccttgat tacgtcttct aaaacatccc atacttcgtc ttcttgacgt
    49921 tcgattttac gtttcgcatt tttgatgttt gaagctagtt cgcgttgaac aagctcacgc
    49981 atcacgaatg gtttgaataa ttcaatggcc atttcttttg gaagtccaca ttggtacatc
    50041 ttcaagaaag gtccaacaac gataacggaa cgacctgagt agtcgacacg tttacctagc
    50101 aagttttgac ggaaacgacc ttgtttccct ttcaacatat gagaaagaga tttcaatggg
    50161 cggttacctg gtccagtaac tggacgtccg cgacgaccgt tatcgatcaa tgcatctact
    50221 gcttcttgca gcatacgttt ttcattttga acgatgattc caggtgcatt caagtctaac
    50281 aaacgtttca aacggttatt acggttgatt acacgacggt aaagatcatt caagtcactt
    50341 gttgcaaaac gtccaccttc taattgaacc attgggcgta aatctggtgg aataacaggg
    50401 ataacgtcca taaccatcca gcttggttga tttcctgaag cgcggaatgc ttctaaaata
    50461 tccaaacggc ggattgcacg tgtacgtttt tgtccttgtg cagatttcaa ttcttctttc
    50521 aattcggctg cttctgcatc tagatcaaca ttatcaagta attgtttaat cgcttctgca
    50581 cccatagcag cttggaattc ttgtccatat tgttcacgtt tttcgcgata ttcgcgttct
    50641 gtcaacaatt gttttttctc taaattcgta tttcctggtt cgatgactac atatgaagca
    50701 aaataaatga tttcttccaa agcgcgtggg ctcatgtcta atacaagacc catacgtgaa
    50761 ggaatccctt taaagtacca gatatgtgaa acaggagctg ctaattcaat atgtcccatg
    50821 cgttcacggc gaactttcga acgagtaact tccactccgc atcgatcaca aacgattcct
    50881 ttataacgga tacgtttgta ttttccgcag gcacattccc agtcttttgt aggaccaaaa
    50941 atccgctcac agaacaaccc ttcgcgttca ggttttaagg tacgatagtt aatcgtctca
    51001 ggttttttta cttcaccgta agaccagctt ctgatttttt cgggagaagc caaacctatt
    51061 tgcatacttt cgaatttatt tacatcgatc aaaaggggtt ccctccattt catttaatgg
    51121 caaaccgcaa gacggctgat cttcgaccgc cttgcagctc atagaccgga ttagtctaaa
    51181 ttatcttctg cggtttcaaa gttttggatg acatcgtctt tttcatcttc cacttgttca
    51241 gcagctttct tttctaattc tttggcagtt tgctgttcgg caaattttgt caaagcatca
    51301 acagtgatca aatcgtcgtc ttcatcgtcc atgtcgcgaa gttcgatctc tgtttcttcg
    51361 atatccaaga cacgcatgtc cagacctagt gattgcaatt ctttcaccaa tacgcggaat
    51421 gattccggta cacctggttt tggaattggt tcacccttga cgattgcttc gtatgttttc
    51481 acacgtccga ctacgtcatc tgatttgtat gtcaagattt cttgtaaagt ataagccgca
    51541 ccgtaagctt ccagtgccca tacttccatt tcaccaaaac gttgtccacc aaattgagct
    51601 ttacctccca atggttgttg tgtaaccaat gagtaaggtc cgattgaacg tgcatgcaat
    51661 ttgtcatcga ccatgtgagc aagtttgatc atgtacatca caccgacaga cacacgtcca
    51721 tcaaatggtt cacctgtacg tccgtcgtac agaacagttt tcgcatcgct ggccataccg
    51781 gcttcacgaa ctgtttccca tacgtcttca tcacttgcac catcaaatac tggcgttgct
    51841 acgtggatac ctaactgacg tgcagccata cccaagtgta attccaatac ttgcccgatg
    51901 ttcatacgtg aaggcacccc taaaggattc agcatgatat cgattggtgt tccatcaggt
    51961 aggaatggca tatcttcttc cggcataata cgggatacaa cccctttatt tccgtgacga
    52021 ccggccattt tatccccttc atggatttta cgtttttgaa cgatataaac acgaactaac
    52081 atgtttacgc ctggtgacaa ttcatctcca gcttcacgag taaagatttt cacatcgtga
    52141 acgataccgc cgccgccatg tggtacacgt aatgatgtat cgcggacttc acgagctttt
    52201 tcgccaaaga tcgcatgcaa tagacgttct tctgcagata attctgttac cccttttggc
    52261 gtgactttcc ctacaagcaa atcgccatct tggacttctg caccaatacg gatgataccc
    52321 atttcgtcta aatcttttaa tgcgtcttcc ccgacattag ggatttcgcg tgtgatttct
    52381 tcaggtccta attttgtatc gcgggcttct gattcatatt cttcaatatg gatagaagtg
    52441 tatacgtcat cttttaccaa acgacggctc atgatgatcg catcttcata gttgtaccct
    52501 tcccaagtca tgaaaccaac taaaacgttt tggcctagag ccatttcgcc ttgttccata
    52561 gatggtccgt ctgccagagt atcccctttt tcgactttct cacccaaatg aacgattgga
    52621 cgttggttgt agcttgttcc ggagtttgaa cgacggaatt ttgttacatc gtatttatct
    52681 aatgcaccgt tgtcgcggcg tacgcggatt tcagaagcat caacgtattc aacgacaccg
    52741 tcatgtttac ataacaaagc agctcctgag tcatgcgctg atttgtattc cataccagta
    52801 ccaacccatg gtgcttgagg attgatcaac ggcactgctt gacgctgcat gttggcaccc
    52861 atcaaggcac ggttggagtc atcgttttcc aagaaaggaa tacatgctgt cgcaacggca
    52921 actacttgtt taggtgatac gtccatgtag tctactttat caatagatac ttctaagttt
    52981 tcactttgag cacgagccat aacaacgtct tgagcaaatg ttccatcttc attcaatggg
    53041 ctgtttgctt gggctacgat gtaatggtct tcgatatcag ctgtcaagta gtcgatttgg
    53101 tcagtaacac gacctgtttc acggtctaca cgacgataag gtgtttcgat aaatccgaat
    53161 ttatttactt tcgcataact ggacaaacta ttgatcaacc cgatgtttgg gccttcagga
    53221 gtttcgatcg gacacatacg gccatagtgg gagtagtgaa cgtcacgaac ttcataaccg
    53281 gcgcggtcac gagtcaatcc gccaggtcct aaggctgaaa gacgacgttt gtgtgtcaat
    53341 tcgccaagag ggtttgtttg atccatgaac tgtgacaact gagaagaacc aaagaattct
    53401 ttgatacttg ccacaactgg acggatattg atcaattgtt gaggtgtcaa tgtttcagta
    53461 tcttggatcg acattctttc acgaaccaca cgttccatac gtgctagccc gatacggaat
    53521 tggttttgta aaagttcacc gactgaacgg atacgacgat ttcctaagtg gtcgatatca
    53581 tcgacattgc cgataccttc catcaagttc aagaaatagc tcattgaagc aatgatgtcg
    53641 gctggacgaa ccgtttttac agctgcttct ggatagccgt ttccgatcac gtttacttca
    53701 cgttcagggt ctcttggtga aaatactttg atgacttgga cagtcattgg atctgtgacc
    53761 acaccgtctt ctgatggata gtaagtcact gaatttaggc cattatcaat gaaaggagct
    53821 agtgtttcca tgacttggtg agtcagaact gttccttttt caacgatgat ctcgcctgtt
    53881 tctggatcaa ctaatgtttc agctaatgtc agattcaata gacgtgtttt caaatctaat
    53941 tttttgttta ctttgtaacg accaacgttt gctaagtcgt aacgttttgg atcgaagaaa
    54001 cgagcattca gcaagttacg tgagctgtct gctgtttttg gttcgcctgg acgcaaacgt
    54061 tcgtaaacgt ctttcaaacc ttcttctgtt cttgagtcgc ttgcgttttt atgcaagtct
    54121 ttttcgactg tattgcgtaa tgtttcgctg tcgccgaaga tttcaaagat cgtatcatcg
    54181 gaaccaaatc ctaacgcacg aactaatacg gttaaaggaa tcttacgtgt acggtcgata
    54241 cgtacataag agatgtcttt tgcatcagtt tccatttcta gccaagctcc acggttaggg
    54301 ataacagtag aaccgaatcc ttcttttccg tttttgtcga cttttccatg gaaatagaca
    54361 cctggtgaac ggactaactg agaaacgatt actcgctctg ccccgttgat gatgaatgtt
    54421 ccttgttctg tcattaatgg gaaatcaccg aagaatactt cttgtgcttt gatttcgcca
    54481 gtctcgcggt ttgtcaaacg caatgttaca tgtaatggtg cagagtagtt tgcatcatgc
    54541 gcacgagctt ctgctactgt atactttggt tctttcaatt cataatctac aaattccaaa
    54601 gatagattgc cattgaagtc atcgattggc aaaatgtctt caaacatttc tctaagtccc
    54661 tcatctaaga accattggta agagtctgtt tgaatttcga tcaaatttgg taattccaac
    54721 acttcactga ttcttgcgaa acttctacgt tcgcgatgtt ttccgtattt tactacgtgt
    54781 ccagccaagc tcttcacccc tctaaaatgt cattcaaaaa gactacccga tcaattgtta
    54841 caataatatt tcaaatatta tttttaggta acaacagaca ttttttgcgg cttttaggca
    54901 aaaaaaaacc aaaaatagaa cattctcttg aaaccttact tcgtgagctt ctacttttgt
    54961 ttccttatat taaagccgaa acggacaata tttcgtttct gccttttctt catcagatag
    55021 tttttgcaac ttcatatact acacttattt tctataaaag tcaacacttc ctggcgtttc
    55081 ttctgctttt tcgcaacatt ttcttaatgt tttcaatttt atgttttcaa ttatctgaca
    55141 attcttaatt gacagacctt tttatctcgg ttatacttta gaaaattcat tttgtggagg
    55201 aacttctatg cgaaccaaca tcaaccaaat cgcaccaaca caactgaata acttttactt
    55261 tagctacttt agataggttt gtattcatca tgatggatac aaacgttaaa cgacagtttg
    55321 tatctatgat ggctaaagaa ctttgtattg cagcaaaaag ccacgtagac aaaatgctaa
    55381 gtggctgagc agtgaaaata caaagtaaaa gtatcaagca ttctactttt tcaatttatt
    55441 ttccgacttt tcaatccatt tggacatttt gtctgaatgg attttttgtt tcccaaaatt
    55501 aaggaggaaa aagaaatgaa aaaaaatata atcatcggat taggcgctgc cctgctacta
    55561 gctttaggag gttgcgcaca aaaagacaat tccgcagagg catcagatgg acaaaaaaca
    55621 attggcgtat tgcaacttgt acaacataac tcgttagatg ctgcctataa aggattcaaa
    55681 gaaggattag cagaagaagg gtataaagaa ggcgataatc taacaatcga ttatcaaaat
    55741 gcccaaaaca atcaagacaa cctgaaaagt atgagtgaga aactcgtcaa agaagatcct
    55801 gatttgctac ttggaatcgc cactccagca gcacaatctt tattaaatga aacaaccact
    55861 atcccgatga ctgtcacagc ggtcacagac ttggaacaag cccatttagt cacatccaat
    55921 gaaaaacctg gcggcaatgt gactggcacg acagatatgg tgccaatcga aaaacaaatc
    55981 ggcttactgt taaatatcgt gccagacgcc aaaacaatcg gcatcatgta taacaacggt
    56041 gaagcaaact ctaagatcca agctgatttg gcagaaaaag aattgaaaaa agcgggcgtc
    56101 aaagtcaaag tactgacagc aaattccaca aatgatgtcc aacaagtgac gaaaagtcta
    56161 gctaaagatg tagatggaat ctatattcct actgataaca cgttcgcaag tgcggcaagt
    56221 gttgtcggtg aagtcgcaaa agaaacaaaa acacctgtcg ttgctggcgc agttgatcaa
    56281 gtcaaagacg gcggtctagc aacagtagga atcgactacg aaagcttggg taaacaaaca
    56341 gggatcatgg cagcaaaaat cttagacggc aagaatccaa gtgaacttcc tgtcgaaaca
    56401 gcgaatgatt tggaactgta tgtcaataaa gacatggcca aagcattagg catcaatcca
    56461 gacagcatca aagaagctga ataaaacaca ggaggattct catgacaaat ttgctctctc
    56521 ttttcttatc atctgcatcg caaggggtct tatgggccct acttgcgatt ggtgtatacg
    56581 tcactttccg tatcttggac attgccgact tgactgctga aggaagcttt cctttaggtg
    56641 cagggatcgc ggcagtaagt attacaaatg gctatcatcc attgacagct tgtcttctag
    56701 gctttttagg gggtgcggca gcagggcttg tttccggact gcttcacaca aaattgaaaa
    56761 ttcccgccct tcttgcaggg atcatcacca tgactggttt atattctgtc acatcccgtg
    56821 tgatgggtgc gccgaacatc tctttattgg gtcagccaac gatctttcat tgggtcgagt
    56881 cattcggcat aacaaaagac aacgctgtac tgatcgtcgg tctgcttttt gctttgatcg
    56941 ttgtatgttt acttgttttg ttcttacgta cagaaacagg acttgctatt cgtgcaactg
    57001 gcgataatct ggcaatgagc gaagcaaacg ggatcaacac agataatatg aagatcatcg
    57061 gttatatgat ttctaatgga tgcattgctc tttctggctc cttgcttgcg caaaacaacg
    57121 gctttgctga tttaaattct ggtattggaa cgatcgtaat tggacttgct tctattatca
    57181 tcgcagaagt tttgttacgt aaccagccac tatttctccg tctcttgact gtcgttttag
    57241 gtgcggtcat ttatcgtttt attttagcgt tagtcttcga actgaatgtt gaaccaagtg
    57301 attcgaaact tgcttctgct ttcgtgctag tgatctgtct ttctttcccg cagatccagc
    57361 aaaaattcca tttacctcaa aaaaagaaag gcggtagtgt caaatgaatg acgtcttaac
    57421 attggaaaat ctccatcata cctttgaaaa aggaacgatc aacgaaaatc atgtcctgaa
    57481 aggcattaat ctttccttag atcccggcga cttcgtgacg atcatcggtg gaaatggggc
    57541 tggtaaatct actttgctga acagcatcgc cggtacattt tctgtcgatc agggtcaaat
    57601 tttattgaat ggaaaaaata tcacgaaaaa atctgttgtc gaacgttcga aatccatcag
    57661 tcgcgtattc caagatccta aactagggac agccgttcgt ttaacggtag aagaaaatct
    57721 tgctcttgct atgaaacgag gaaaaaaacg cggcttcttc cgtggtgtca aaccacaaga
    57781 ccgaacattt ttcaaagacc agctggttcg gctaaatttg gggttggaaa atcgtttatc
    57841 ctcagaaatc ggtttgctgt ctggaggaca acgtcaagct attacgttat tgatggccac
    57901 attacagcgt ccagaactga tcttattaga tgaacacact gcagcgcttg accctgctac
    57961 ttccaaaacg gtgatggaat tgacagaaaa gctgatcact gagcagaatc tcactgcttt
    58021 tatggtcact catgacatgg aagacgcgat ccgctatggg agtcgactga tcatgctgca
    58081 tcaaggaagg atcgtcgtag atatccagca agaggaaaaa cagcagctca cagtgcccca
    58141 attattagcg ttgttcaaac aaaacagcgg cacggcatta aaagacgatc aagtactttt
    58201 atcttcataa tcagaaagag gatgggacaa aaaatgaacg cccaccctct tcttttttct
    58261 ctttccttct ttcgtttttg ctttatgtat caaccgttgt ttcttcgaaa actattttgt
    58321 tctctccttc ttcctgatag aatggatggg aaaggagctt gatgccatga caacgaaaga
    58381 caaggtactt caattattga aaaagacacc agattttctt tccggagaaa agttggcaca
    58441 gcaactggaa gtttcccgga caagtatttg gaaagccatc aaagaattgg aaaaggcagg
    58501 ctatcgtttt gagcacgggc ctacagggta tcgttacctg ccctctgacg tactagatgc
    58561 aaaagaaatc cagcaagagc tacggtcgtt tattcctgat ttgaaagtac aaacgatgtt
    58621 gacttctgaa tctacgatga aagatgtcaa actggcagca gctcaaggag attctgtttc
    58681 gaagttattt gttgctgata cacaagaaca agctcgtgga cgttttggac ggcctttttt
    58741 cgctgaacct ggacgaggaa tctacatgag tctcttgctc catccagaca aacggtttga
    58801 tgaattgcct caatatacga tcatcgcagc cagtgcctgt gtgaaagcca ttgaatctgt
    58861 aaccggtcgt tctgcttcga tcaaatgggt caatgatatc tacatggatg gaaaaaaagt
    58921 ctgtgggatt ttatctgaag cagtcagtga tatggaaagc ggcaggatca gtcatatcat
    58981 cattgggatc gggcttaatt tttctgttcc tcaaaatcat tttccagctg atctccaaga
    59041 aaaagccatc tctgtctttc ccgacggaca agctagtgtc acaaggaatc agctaatcag
    59101 caaaatctgg caagaattgt tcacttatct ttctcaccca gaaaaagcgt tggacttcta
    59161 taaagaaaaa tcattcgtat tgggaaaaac cgtgtcgttc aatcaaaaag gaacgactta
    59221 tgtcggtctt gcaaaagaaa tcggtgatca tggcgaactg atcgtccaaa caaatgaaca
    59281 gaagatgagt ttgtcttctg gcgaaatcag tctcacatct atccgtacgc aataattatc
    59341 agatttcaca aaaggacacc tgatctcata cagtgtcctt ttttctgaat tctcttcaaa
    59401 agactctcct tattctatca gctgacagtt tctctatcct ctagaaaaag gtattctaaa
    59461 aatatctata aagcatggta cactttcttt aaatgaatca atgcaaaaaa caagagagtc
    59521 atcagtttac acgatcaaaa gagatagcag gccgcttcct ttttcaatct tatagataga
    59581 ccatgggtaa cgataaaaac aaaaaagaac ttgcgactta ttttgccgta agttcttttt
    59641 tagctagtgc cttaatctct taatcccaac aaacgtctcg catagatcac ctgaccagag
    59701 tgcatagcag catcatcaat aatagaaacg agacgcattc ctcgtgtgac tggtggtgtc
    59761 cagttctcgt caattacttc atctagctcg gaaggttcca gccttcttaa gtaagaaata
    59821 gcaaaatcag cagctcctcg caagtatcct agcagatctt ctatttgatt agcttggatc
    59881 tgctttgctt gttccagact atgcttccaa tcttgttcgt tatctgctat cgtcatcgga
    59941 aaccggcttt cccagtcttg actatgccaa attggagaag ttcctgctaa atcagcaatc
    60001 tggaaatcta attctcgagc ggtatgccaa gccagccaag tcattgattt gatctgcggg
    60061 gctctatctt ccactggaaa acgattggcc tcctcaatag agacgccttc aaacaaacgt
    60121 tcaaaccgat cgtatgcccg atccacactc tcgcatagca tatctaaata atccatttat
    60181 tttcctcctt tttatttatc ctacttactt tttcctaatt ctaggatacc tacttatatg
    60241 ttactacaca cccttatttt ttacacttta acagtcacca tcatcaatag tttggagatt
    60301 gaaagaaaaa gatagtgtcg aactatcaat tgaacaagaa gcaacaatat gaacgtttca
    60361 ttaatattct ttaaataaac aatgattttt caaacgaaca gtttaagact aggagaaaaa
    60421 gagtataata ggaaaatgtt tgaaaggaaa ggaaggggaa aaatgaaaaa aagggcaagt
    60481 ttactagtcc tagttgcttt gttgttcaat atcttttcgt atggtgtggc cgtttcagcg
    60541 gaaacataca ttcctaaaga ccctgggaat atttataatg atctaactgg taactatggc
    60601 ttgttaggaa ttgctagtca attccacgta tttgctaaaa ataagacaac tgtgaatgca
    60661 catacagacg gaaatatagc aacacatgaa cttgatgcaa aaaataattt tggtacagag
    60721 cttcatgaag gtttattgaa ccaagaaata aattatatac aaaaaactga ttctttcgct
    60781 aattcttcag gcatacctac aggtagcaca agaatgaata aatttgtcgt tggcagtaac
    60841 gtggatgtag cacttcaaga tggtcatcct acagtcaatg gatccaggct tgatcactta
    60901 actccagatg atttttataa agatcgtgct gggcatgaat atattgattt cgagcaggaa
    60961 tttgctaaat tgaatgtagc agcaaatgat cttgcaacga tcactccagc taaaacatat
    61021 actgctgcag attttccaga catgaacaat cggacaatcg atttaactga tttatcagat
    61081 accgggtttt tattggtaaa tatcgatgca gaagtgttaa cgatgaatac gccacttcaa
    61141 atcattaatc caaatgatca agtagttgta tttaatgtca tcaacagttc ttctgcattg
    61201 aacgtacagt caccaatcaa atacaatgat cgttcaaatc atgaaacaga agatttttcg
    61261 gatgcgaata tctcttggaa ttttggaaat gagatgactg atttgacaat cagtgctcct
    61321 tttcaaggaa caatccttgc gcctaatgct actatccgca ttactcaaaa ccaagacgga
    61381 acgattatag gaacaaatgt gattttagat gcagctacca atcgttggga tcctaacgaa
    61441 atatttatca gcgacaatgg tacagatacg acagacacaa gcgacagtac agatacatct
    61501 accacaagtg atagctcaga ttcatca
//
LOCUS       DBBGSZ010000014        59668 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.014, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000014 DBBGSZ010000000
VERSION     DBBGSZ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 59668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59668
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.014"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(451..1761)
                     /locus_tag="ACIZE5_001214"
     CDS             complement(451..1761)
                     /locus_tag="ACIZE5_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004650 - polygalacturonase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28 protein"
                     /protein_id="HGC6108371.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3191)
                     /locus_tag="ACIZE5_001215"
     CDS             complement(1773..3191)
                     /locus_tag="ACIZE5_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6108372.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3431..4999)
                     /locus_tag="ACIZE5_001216"
     CDS             complement(3431..4999)
                     /locus_tag="ACIZE5_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HGC6108373.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5003..5413)
                     /locus_tag="ACIZE5_001217"
     CDS             complement(5003..5413)
                     /locus_tag="ACIZE5_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HGC6108374.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5410..6333)
                     /locus_tag="ACIZE5_001218"
     CDS             complement(5410..6333)
                     /locus_tag="ACIZE5_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030599 - pectinesterase activity
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pectinesterase family protein"
                     /protein_id="HGC6108375.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6330..7208)
                     /locus_tag="ACIZE5_001219"
     CDS             complement(6330..7208)
                     /locus_tag="ACIZE5_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HGC6108376.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7195..8532)
                     /locus_tag="ACIZE5_001220"
     CDS             complement(7195..8532)
                     /locus_tag="ACIZE5_001220"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HGC6108377.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8535..9638)
                     /locus_tag="ACIZE5_001221"
     CDS             complement(8535..9638)
                     /locus_tag="ACIZE5_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGC6108378.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9712..11220)
                     /locus_tag="ACIZE5_001222"
     CDS             complement(9712..11220)
                     /locus_tag="ACIZE5_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGC6108379.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11186..11878)
                     /locus_tag="ACIZE5_001223"
     CDS             complement(11186..11878)
                     /locus_tag="ACIZE5_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGC6108380.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11900..12874)
                     /locus_tag="ACIZE5_001224"
     CDS             complement(11900..12874)
                     /locus_tag="ACIZE5_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6108381.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13174..14046
                     /locus_tag="ACIZE5_001225"
     CDS             13174..14046
                     /locus_tag="ACIZE5_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6108382.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14504..16702)
                     /locus_tag="ACIZE5_001226"
     CDS             complement(14504..16702)
                     /locus_tag="ACIZE5_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6108383.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16934..17926
                     /locus_tag="ACIZE5_001227"
     CDS             16934..17926
                     /locus_tag="ACIZE5_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6108384.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17986..19407
                     /locus_tag="ACIZE5_001228"
     CDS             17986..19407
                     /locus_tag="ACIZE5_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HGC6108385.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19400..20899
                     /locus_tag="ACIZE5_001229"
     CDS             19400..20899
                     /locus_tag="ACIZE5_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HGC6108386.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20938..22332
                     /gene="uxaC"
                     /locus_tag="ACIZE5_001230"
     CDS             20938..22332
                     /gene="uxaC"
                     /locus_tag="ACIZE5_001230"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HGC6108387.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22491..23174
                     /locus_tag="ACIZE5_001231"
     CDS             22491..23174
                     /locus_tag="ACIZE5_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HGC6108388.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23176..24012
                     /locus_tag="ACIZE5_001232"
     CDS             23176..24012
                     /locus_tag="ACIZE5_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HGC6108389.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            24023..25777
                     /locus_tag="ACIZE5_001233"
     CDS             24023..25777
                     /locus_tag="ACIZE5_001233"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6108390.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(26053..26394)
                     /locus_tag="ACIZE5_001234"
     CDS             complement(26053..26394)
                     /locus_tag="ACIZE5_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HGC6108391.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26462..28633)
                     /locus_tag="ACIZE5_001235"
     CDS             complement(26462..28633)
                     /locus_tag="ACIZE5_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HGC6108392.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28844..29701
                     /locus_tag="ACIZE5_001236"
     CDS             28844..29701
                     /locus_tag="ACIZE5_001236"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGC6108393.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            complement(29772..30629)
                     /locus_tag="ACIZE5_001237"
     CDS             complement(29772..30629)
                     /locus_tag="ACIZE5_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGC6108394.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30614..33316)
                     /locus_tag="ACIZE5_001238"
     CDS             complement(30614..33316)
                     /locus_tag="ACIZE5_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HGC6108395.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33329..34618)
                     /locus_tag="ACIZE5_001239"
     CDS             complement(33329..34618)
                     /locus_tag="ACIZE5_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HGC6108396.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34768..35814
                     /locus_tag="ACIZE5_001240"
     CDS             34768..35814
                     /locus_tag="ACIZE5_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6108397.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35816..37969
                     /locus_tag="ACIZE5_001241"
     CDS             35816..37969
                     /locus_tag="ACIZE5_001241"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HGC6108398.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38442..39893)
                     /locus_tag="ACIZE5_001242"
     CDS             complement(38442..39893)
                     /locus_tag="ACIZE5_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGC6108399.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39890..41614)
                     /locus_tag="ACIZE5_001243"
     CDS             complement(39890..41614)
                     /locus_tag="ACIZE5_001243"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGC6108400.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41607..42221)
                     /locus_tag="ACIZE5_001244"
     CDS             complement(41607..42221)
                     /locus_tag="ACIZE5_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HGC6108401.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42566..44023)
                     /locus_tag="ACIZE5_001245"
     CDS             complement(42566..44023)
                     /locus_tag="ACIZE5_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6108402.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(44064..44984)
                     /locus_tag="ACIZE5_001246"
     CDS             complement(44064..44984)
                     /locus_tag="ACIZE5_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6108403.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44996..45943)
                     /locus_tag="ACIZE5_001247"
     CDS             complement(44996..45943)
                     /locus_tag="ACIZE5_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6108404.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46422..47141)
                     /locus_tag="ACIZE5_001248"
     CDS             complement(46422..47141)
                     /locus_tag="ACIZE5_001248"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGC6108405.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47190..48836)
                     /locus_tag="ACIZE5_001249"
     CDS             complement(47190..48836)
                     /locus_tag="ACIZE5_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HGC6108406.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            49015..49605
                     /locus_tag="ACIZE5_001250"
     CDS             49015..49605
                     /locus_tag="ACIZE5_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGC6108407.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49697..51202
                     /locus_tag="ACIZE5_001251"
     CDS             49697..51202
                     /locus_tag="ACIZE5_001251"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HGC6108408.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51286..52638)
                     /gene="celB"
                     /locus_tag="ACIZE5_001252"
     CDS             complement(51286..52638)
                     /gene="celB"
                     /locus_tag="ACIZE5_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HGC6108409.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52638..53156)
                     /locus_tag="ACIZE5_001253"
     CDS             complement(52638..53156)
                     /locus_tag="ACIZE5_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108410.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53172..53498)
                     /locus_tag="ACIZE5_001254"
     CDS             complement(53172..53498)
                     /locus_tag="ACIZE5_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HGC6108411.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53511..55490)
                     /locus_tag="ACIZE5_001255"
     CDS             complement(53511..55490)
                     /locus_tag="ACIZE5_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGC6108412.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55511..55825)
                     /locus_tag="ACIZE5_001256"
     CDS             complement(55511..55825)
                     /locus_tag="ACIZE5_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HGC6108413.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55993..56286
                     /locus_tag="ACIZE5_001257"
     CDS             55993..56286
                     /locus_tag="ACIZE5_001257"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HGC6108414.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56364..57476)
                     /locus_tag="ACIZE5_001258"
     CDS             complement(56364..57476)
                     /locus_tag="ACIZE5_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HGC6108415.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57629..58477
                     /locus_tag="ACIZE5_001259"
                     /pseudo
     CDS             57629..58477
                     /locus_tag="ACIZE5_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(58830..>59668)
                     /locus_tag="ACIZE5_001260"
     CDS             complement(58830..>59668)
                     /locus_tag="ACIZE5_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HGC6108416.1"
                     /translation="YQLVETQAPTGYELDATPIEFEIERSQTAVVELTKANRLTPGGV
                     VLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGVYQLVETQAP
                     TGYELDATPIEFEIERSQTAVVELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDA
                     NGTVLQSGLTTGADGKLAIDGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIF
                     LTKENRKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKR
                     NI"
BASE COUNT        17831 a        12195 c        10434 g        19208 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt
     3181 tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa ttataactct
     3241 ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa
     3301 aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt tacataacaa
     3361 tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc tcatttatta
     3421 aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa tcagcataac
     3481 ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca gtaaaccctc
     3541 ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca gttgatacgt
     3601 ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa gtcttctttt
     3661 ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat tctatcatac
     3721 gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa ttggattcat
     3781 ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat tcaaatgctg
     3841 tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt tcgaaggtag
     3901 attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt gtatcacacc
     3961 aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct ccttcaaatg
     4021 tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca atcattattt
     4081 cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac gtccaataca
     4141 cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt ctggtacaaa
     4201 gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt cctgtacatt
     4261 gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga tcaagctcgt
     4321 aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt cctgtaccgc
     4381 cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt gcctccgttt
     4441 tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc ttcttctctg
     4501 catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga cgataatccc
     4561 atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa gaaggatcaa
     4621 agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca gatgcagtga
     4681 tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct gtgtaaacaa
     4741 gataaaacaa tccatcagca taactgattt gtggcgccca tatacttcca tttgtaggat
     4801 ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag ttgactaaat
     4861 ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca ataatgtaat
     4921 accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa ataggatttt
     4981 tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga tataaactga
     5041 atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga gtgccaatca
     5101 acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat tttcctttag
     5161 cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca acggcaaaca
     5221 gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt gaatgatcta
     5281 cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt aaagtaactg
     5341 ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc aatagttccc
     5401 attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag gtcttttgat
     5461 cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat ttttcttgtc
     5521 atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg cttcaaataa
     5581 gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat caggttctgc
     5641 agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg tagatgctgc
     5701 tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat gaaaaacggc
     5761 atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt cataggtctg
     5821 acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat ctttttgcaa
     5881 atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac agttttttaa
     5941 agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt ctcctggacc
     6001 tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta agaaaaaagt
     6061 agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg caaaacgatt
     6121 accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc tgctttctat
     6181 atattcatca tatcttcctt cttttactat caagaccttt ggatggctat ccggcaggcc
     6241 tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat ctatagcatt
     6301 ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa ttgtttccaa
     6361 atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga agaaaagttt
     6421 tctggactac ccattgattg atactttttg tccagccctt ttctcagctt cagtacgcct
     6481 tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg cggagcgatt
     6541 ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata gtaataaaac
     6601 ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg tgccgctaga
     6661 tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa taagcctccc
     6721 atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt ctccaaataa
     6781 tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc tgttaataaa
     6841 aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc ccaagcatca
     6901 atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg agaagctaag
     6961 taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc gtgagaatgc
     7021 aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag ggctggtact
     7081 gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt ttgtttttct
     7141 cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa aaaatcattc
     7201 aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg attgatttga
     7261 ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg gtccctcgtg
     7321 attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat aaaatccttg
     7381 tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg catcttgggc
     7441 catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg ctaatccata
     7501 aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat ggatccttct
     7561 gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat acggttcttt
     7621 ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca cattatccat
     7681 gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc tagatttcaa
     7741 tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat tacgaatact
     7801 accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg tgcaatttgt
     7861 gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg ccttgattgc
     7921 aatacagtca tctcccacgt caatatggca attactaata cgcacatttt tgcatgattc
     7981 tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca agttatcaaa
     8041 cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt ggtgactgga tcaatttaat
     8101 atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac gaggataagc
     8161 gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc catctaatgt
     8221 accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg aagcataaac
     8281 ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg gatcgtcaga
     8341 gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta aaaataaagc
     8401 tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac ttgctgcagc
     8461 atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc caaatgtcaa
     8521 aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa tgcaccaacg
     8581 cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga accatctcgc
     8641 tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag ccagccttct
     8701 tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac ttgtggaagc
     8761 cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta aacaaacata
     8821 ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt tacttgatac
     8881 catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt ttctagaatt
     8941 tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc tgctgcagcc
     9001 atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt ttttggatca
     9061 gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt ttttggatcg
     9121 aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc tttttcttca
     9181 ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc atccaaccaa
     9241 atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg tggatggttt
     9301 gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc tgtttctttg
     9361 tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc ttcaacgctg
     9421 tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt tatgaaatca
     9481 aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag tacgacgcca
     9541 tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg tgttctttcc
     9601 atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc tttaaaaatt
     9661 aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat attactgtgc
     9721 cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt gtgctttcca
     9781 gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt attgcaccgt
     9841 agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg gtgaatccaa
     9901 tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt gattagagaa
     9961 ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac gagagcttga
    10021 taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag aaccatcatc
    10081 attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca catcttcttc
    10141 taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt ttacttgaga
    10201 tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat gataaccgcc
    10261 gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt gaataccttg
    10321 acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag ttcttccttg
    10381 tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg ccaaatagcc
    10441 attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg tatcaaattc
    10501 tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa aataagaagt
    10561 gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa aaccaactgt
    10621 gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta cttcataaag
    10681 ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt ttcgaatgac
    10741 taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac cgtcgatact
    10801 cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt ttaaatattc
    10861 tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt ttttcaacat
    10921 cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag ttgttaatct
    10981 ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg ttttttcttc
    11041 gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat ttaaccaagt
    11101 gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc tgccgcatgc
    11161 ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg cttttttcat
    11221 aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt tctgtatatg
    11281 agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact gcggaaaaga
    11341 agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc atcagataaa
    11401 tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat ccgaataaaa
    11461 atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg attgggaaaa
    11521 tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc ctaagatacc
    11581 aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca tatatccagc
    11641 tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt ttcgtcaaag
    11701 gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca tacgatgcag
    11761 gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga aaattcaaat
    11821 aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac tgcagcatat
    11881 ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg gcaatcttat
    11941 tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt gctgtactga
    12001 aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa atttctgcaa
    12061 cgcttcgatt caatgaattc aataacaagt acatatgctc gaaccctaag tctaatgtct
    12121 gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc aatgtaacat
    12181 gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac aactgtgtat
    12241 cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct ttccagatca
    12301 cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg attttttcaa
    12361 atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa aatacataag
    12421 taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc gtttgaatcc
    12481 cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg attggcatcg
    12541 gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat aatgtaaaga
    12601 atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga cttcccatta
    12661 ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata ggaagatacc
    12721 taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat ttattcgttt
    12781 tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc gatagcgtca
    12841 gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt ttgtgaatgt
    12901 ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat catttttacc
    12961 gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat aaagtgtatt
    13021 ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga cacttagcat
    13081 aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata gaaacagaaa
    13141 catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc tataggagaa
    13201 agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat ctgtatcgtt
    13261 ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt cgcgaaaaag
    13321 tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct ttctacgccg
    13381 accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac gatcgtcagt
    13441 atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt tggtcgaggt
    13501 ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat tccaacgttc
    13561 ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct gcctgtggct
    13621 gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc ggatagtttg
    13681 gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa aattatgctg
    13741 ccattagcgt taccgtctat tgctactatc tcgctttttt atgctgttac ttactggaac
    13801 acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat acagattctt
    13861 ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc cgttgatgtg
    13921 attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt gcctatgctg
    13981 attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg ttctgtcaaa
    14041 gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag cttcaagaaa
    14101 taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc ttatttttcg
    14161 aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt cagccttgag
    14221 cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa taagaagcga
    14281 ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat agcctgtctc
    14341 ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca gttctttttg
    14401 cgtgcttagc cttgaaattt aactatccat aaatacaaat actagggtta ttctaacttc
    14461 ttttattgct tgaatcagtc cacaagaaaa acagcctctt gattcacaaa tatttttttc
    14521 gatattctcc cggcgtaatc gattccttct ttttaaagaa acgaataaaa ttttgcggat
    14581 ttcgatattg caatctttct gcaatctctt ttacggagag gttagtctct ttcaaccatt
    14641 tttttgctac ctctaaacga tgattttgaa caaaatcacc aaatttttct cctgtttcct
    14701 ttttaaatac attacttaaa tagttagggt tataatgcaa cctatcagcg atcacatcta
    14761 aagacagatc acgatcatat tctgtgtaga cgatatgcat aatattctcc gacaaatttt
    14821 taaattcatg atcagtgatt gcttgagagc attctgtgat tggcagaact aattgttcta
    14881 aaacaagttt ttctagttct ttgggatgat aattgttcag tgcttttaca taaatttgtt
    14941 tcatgttatc aaagtttttt gaatctactc ccaataactg tcctaattga acgagttcat
    15001 tgatcaagcg gaccgaaact acttcccgac tcaaaggatt tttattttgt gcaaacaatg
    15061 catcaatcaa ttcatgtact aaattcttca cttcctgatt tccagaacga atggcttcaa
    15121 acaatcgatt ttgttcttct atcggatatc taataagtgt tttttcatga gcagcaggaa
    15181 cgatttcctg ataaaaaata attgaacttg gaccagtatt tacacgataa tacagggctt
    15241 cttttgcccg atcaaccgat tgcttgcttt cattcagcgt ttcgaaccgg ttactgatgc
    15301 ctatactgat agttaaattc aagtattctt ttacacgttt ttgaatgagt cggcaatact
    15361 ccatgacttt tttgcttgct tctgcatcat ctttatccat tcgataaata gtggcttgca
    15421 tttcttcatt caaaacgatc ggcagcattc gattttcctt tggcacaatt tccgtgatca
    15481 tgttgttgat cgctaaaagt agcaaatcac gctccccacc gtgactatct tctaacagat
    15541 cgatttgaac caaagctgta taatagcagt cattttgaga actataacca aattgctgca
    15601 accgctgatc tagttctcgc ctttctactc gatttctaaa taaactaagt acaaatagcg
    15661 tttccagctg tggcttttgg gtaactaagt gtgcacttaa cgcttctttt tctcctatga
    15721 tccgactgac tgattgagcg accaaatcta gttctttccc actgaatcct tttgatttaa
    15781 gattcagacg ttcctgtatt tgagaaatcg gacgggcaaa tctgtccgaa aataagtagg
    15841 aaagaagacc aatgagtcct accagtgtta aagacactgc aactagcccg attctcagat
    15901 tgcggatcat tgcgccaatt gcactagagt caacttctaa tctgtaaatc caattattat
    15961 aatctgattt cagtactata tacgttttat ctttttctct tatcactttc agctgattgt
    16021 aatctagatc cacgtccgtt aatacagttg gttgctcttt attttttact gtctgagtag
    16081 taaaaaggtt gccaacttcg ttttcaatag aaagtatgtc ttctccactt tcaccaacaa
    16141 cttgttctat tgtatgtttc tctatcgtag caattcccaa tgcatatttt tctttttcaa
    16201 acattggcaa agaaatcacc atttcgattc ctttgttttt cttttgccaa aataaattat
    16261 ttttgttatt tatgtacttc tgttgatact tttcaacttc ctcttcggtc agttgactca
    16321 acgatccatt gattactccc catttaccag ccaaactgac taaatcataa ttattatcat
    16381 ccataacaat cgtttctata aaatttagtt ctttcctgat ttcagaataa gtggagtaat
    16441 ctgtatatgt cagcggatgc ttgaatatgt ccgagaaatt tttggtcgaa ccatacgtag
    16501 aaaacgaata ttcaatcgtt ctaattttcc attcaacgtt agttttaact tgcctgagca
    16561 aattcttttt gtctgttaaa taactcgatt cgatcgattc ataggtattc tggtaaatga
    16621 ataaactaaa tcctatgaca agtacggctc ctaataaaaa catcggtaaa aatattttat
    16681 aaaatactgt acttttcttc attttcttcc tctcctcctt ttaaaataaa aggctttcat
    16741 ttttctgtaa aattgatact catctaatta aatgagcatt ccccgctttc aagaatagca
    16801 taattaaaaa taaaaatcca agtaattttt aacgtgtgca atcttttcat atcaaagatc
    16861 tattgactta tcgtagttat cgtaatatga tgaatgcgtt aacaaaaagt gaaaaagtaa
    16921 ggaaaatgat ggaatggtaa cgatcaaaga tatcgctaaa gcagctggcg tttctcatac
    16981 gacagtttct cgtgctttga ataacagcag tttaataaaa aatgaaacaa aacaaaaaat
    17041 acgacaacta gctaaggaaa tgaattattc gccaaactat agtgcaaaag gtttagtgaa
    17101 tcaaaaaaaa tatctaatcg gactattttt ctcaagtttg cataaaggaa cttcatcaaa
    17161 tttcctagca gattccattg caggcatcca ttcagtatta gacacaaatt acagtttatc
    17221 tgttgaaagt atcgatgttg ttgatttaac agaaatcaac ctgcaacgct acgatggact
    17281 gatcgttatg agtcaaagtg atgatgatca gcctttcatc gactatctca aagaaaaaga
    17341 atttcctttc gttgttgtca atcgtcacat caatgatcca gcggttatca acgtcactgc
    17401 cgatgatgcg gccggtgtta tgcaggcagt agattacggt attggatgcg gacatacgaa
    17461 gatcgcttat attggcggaa agaaaaattt tcgttcgaca aaagaacggg aaaaaggggt
    17521 attgaaaagt ctaaaaaaag cgagcatccc tgtcaatcca gcctattttt taacaggaga
    17581 ttacagctta gaaagcggcc tccaaaacat ggaataccta ttatcacttt ctgacctgcc
    17641 tactctggtt ttttgcggca acgacgacat agcgattggt gcattgagag ctgtacattt
    17701 agctggcctc cgtgttcccc agaacatttc tctgatcggg ttcgatgatt ctccagtcgt
    17761 ctcctatctc aatccgccgc ttaccaccgt acgtaagcct ttgaaagaaa tgtgtcaaga
    17821 aggaacaaag cttttactag atttgatcga aggcaggacg atcgaacaat ctaaaattga
    17881 gctctccacc ttgttgatcc ttcgtgagtc gatcaattac ttgtaaacta caagtaattt
    17941 tatataaaaa tgttaacgtg tgcataacac agaaaggaag tttatatgaa aaaactgaca
    18001 aaagaattag tgaaaaaaaa cgaagcacct gtaaaagttc ttcagtttgg tgaaggcaat
    18061 tttatgcgtg gatttattga ttggcagatt cagcagctga ataaccaaca attgtttaaa
    18121 ggtaatgttg caatcattca acctttagaa caaggtcttg gaaatatgat gaaccagcaa
    18181 gataatttat atacggtcat tttacaagga ctcagcaatg gcgaaatcgt tgatacttcc
    18241 gagattatca ccgtagtaga acaaatgatc aatccttatg atgaatggga tgcttatcta
    18301 tctctagcag aaaatgacga cttggcctat atcgtctcca atacaacaga ggcaggaatc
    18361 caattcgtgg agactgataa tttaacagat actcccccac agagcttccc gggcaaactg
    18421 acagcctttt tataccgacg tttcaaatta aacaaagctg gctttaccat cattccttgc
    18481 gaactgattg acagaaacgg cgaacgtcta aaagaaatca ttttacgcta cgcagaaaaa
    18541 tgggatttag aacctgcttt tgttgagtgg ttagaaaaag aaaatgtttt ctgttgtagt
    18601 ttagttgatc gcatcgtccc aggttatcct cgcgaagatg caggtgtttt caatcaacgg
    18661 cataactatg aagatcaatt gatggtcaaa gcagaaccat tcatgctttg ggtgatcgaa
    18721 gggcctaaag aattggagaa tcaactacca ttcaaacagg ctggcttgaa tgtcatcatc
    18781 acagatgata tgactcctta tcgtgaacgt aaggtgcatt tgcttaatgg accgcataca
    18841 gcgatggtcc ctcttgcttt gttggcggaa ttggaaactg tagaagaagt aatgaaagat
    18901 cctttattct ccgcatatgt tgatcagtta ttcaatctag aattgattcc tatgctttct
    18961 ttacctaaag atgaattagc catttatgct gaccaaatca aagaacgttt cttgaatcct
    19021 tttgcccatc acaaattaga agcgatttca ttaaatagtg tttcaaagtt cagcacccgt
    19081 ctgcttccag tgttcaagaa gtatatcgaa gaacaaaatc aggtaccacc gttaatcact
    19141 gtttcactag ctgcgctact tcttatgtat cgaggcgatc aagtaaagcc acatgatgat
    19201 gaaaagacga taagcgaatt tactgatgct tggtctgata atggaacagc tattcctcga
    19261 ttattgcaaa acgctgcgct ttggggagaa gatttgtctc aaataccgaa tgtgacagat
    19321 acagttcaag aaatagctgc aaagatcgat caaaaaggtg tccggtcagt attacaagaa
    19381 atgaaaggaa cgatggtcca tgcttgaaac cctgcaacca acaatgaaat taaatcgacg
    19441 agacagtgtg gtcgtcgcat taacccctat tccaaaacaa acacaactga cgattgatca
    19501 gcaaacgatc accactcttg aagatatccc gcaaggtcat aagattgcat tgggtgattt
    19561 gaaagctgga gacaacgtga tcaaatatgg ctatccaatc ggtcatgtga cgacagacgt
    19621 aactgccggt caatggctgc acactcataa tgtaaaaacc aatctttctg gtgaattgga
    19681 ttatcgatat gaaaaagatg tccatccaag tcattacctt tttgagaacc gaacatttca
    19741 aggttacttg cgaaaaaatg gaaaagtagg gattcgtaat gatttgtttt tagtacctac
    19801 cgttgggtgt gtgaatggca ttgctgaact gatcgtcaaa cagttcaagg aaaaacatcc
    19861 agatctggga cagtttgacc atattacgat tttaaagcat ccttatggct gttcgcagct
    19921 tggaaaagat catcaaaata ctcgagaaat tttagcggac gcagtaaatc atcccaatgc
    19981 cggaggagtt ttagtatttg gattaggttg tgagaacaat acagttcctg aattcaaaaa
    20041 aattttaggt gaatatgatg aagaacgagt gaaatttcta gtggctcaag atgtttacga
    20101 tgagatcgaa caaggtgtgg ctctattaga agagctttta acagcggcgg aaaatgacca
    20161 gcgcatatca gtcccgctct ctaagttgaa tgtcggtttg aaatgcggcg gttctgatgg
    20221 tctatcggga ataactgcta atcctttact tggtgcattt tctgactact tgattgctca
    20281 aggaggcagc acgatcttaa cagaagtgcc agaaatgttt ggcgcagaac aagtattgat
    20341 ggcacgagcg gaaaatgaag aagtttttga ctcaatcgtt gacttgatca atgacttcaa
    20401 acagtatttc ttgtcttacg gggaaccagt ttacgaaaac ccatctcctg gtaataaagc
    20461 aggtgggatc actacattag aagataagtc tttaggctgc acgcaaaaat caggaagctc
    20521 tcctgtcgtt gatgtgctac aatatggcga aaaaatcaga aaaccagggc ttagtttatt
    20581 gcaagctccc gggaatgatc ttgtagctgc ctctgctctt gcttcatccg attgccagtt
    20641 ggtcttgttt accacaggaa gagggactcc gtttggctca tatgtcccaa cggtcaaggt
    20701 atctacgaat acaactcttt ttgaacgcaa aggtcattgg atggatttta atgcaggcgt
    20761 cttattagaa caaccaatgg aagtaatctt agaatcgttt gttcaaaaaa tcatcgctgt
    20821 agctagtgga gaagaaacga aaaatgaaca aaatgacgtt cgagaaattg ccatttttaa
    20881 aaacggagta acactttgat tttcataaaa cagtataaaa agaaagaagg aagatttatg
    20941 tttttatctg atgatttttt attaaaagac gattgggcga aaaagcttta ccattcctac
    21001 gcaaaaaaca tgcccattat tgattatcac tgtcacttag atccaaaaga aatttacgaa
    21061 aacaacaatt tcagcaatct gacagaagct tggttaggag gcgatcatta caaatggcgc
    21121 ttgatgcgag cttgcggcgt gcctgaagaa aaaatcacag gaaatgcttc tgattttgaa
    21181 aaatttttag cttggtgtca aaccgtacca aaaattatcg gaaatccgct ttacagttgg
    21241 tcacatcttg aattgaagcg tttcttcggt attgacttgt tgataaatga agaaaatgca
    21301 gagaaaattt ggacacaagc aaatgaaatt ttggcagctc ctgattttcg ccgtcgggaa
    21361 atcgcaaaaa aatcgaatgt agaagtgatt tgtacaacag atgatcccgc agacgacttg
    21421 cactatcatc agttgcttgc tcatgaagaa ccagatttga aggttctacc ttcattccgt
    21481 ccagataaag cactcaatat tgaaaaagaa ggatttaatg catgggtcac actactggaa
    21541 gaagcagctg accaaacgat caccacctat caagaactga tagaagtctt agggcagcgg
    21601 atagaatact tccatcaaca tggatgtcgt gtttccgacc acgctttaga catcttacgc
    21661 tataaagaag cggatgaaac agtattagaa gagatttttc aaaaagcacg agctaacaaa
    21721 ctattatctt cagatgaaat cgatgcttat cgtacagaaa cactgataca tttgacccac
    21781 ttctatcatt ctcataattg gacgatgcag ctgcacatcc atgcttatcg taactgtaat
    21841 acacaaatgt tggaaaaatt agggcccgat accggctatg atggaatgaa tgatctttct
    21901 ttgactattc ctctgcaaaa attattgaac cgtgcagaag aaacggatca gttgccaaag
    21961 acgatccttt attcattgaa tccgaatgac tatcctgcga ttttagcttt gatgggctgt
    22021 ttccaaaaag aacagaatgg aaaactgcag ttaggttctg gatggtggta caacgatact
    22081 cgagctggta tgcgcgatca attgacacaa tttgctgatg gtagtgcttt ggggaatttt
    22141 gtcggcatgc tgacagattc aagaagtttc ctgtcctaca ctagacatga atatttccgt
    22201 cgtgttcttt gtgaattttt aggcgaaatg gtcatgcgag gagaagcacc tgaagatgaa
    22261 caacttttag gaagtctagt tcaagcgatt agttatacaa atgctaaaaa ttactttggc
    22321 ttttttgcct aattgattaa tagtaacagt aacgaatcaa aaacaggata gtgaaataac
    22381 ggaatccgtt tatccacgtt ttagagaaga agacggacca aatttgctcc gtcttcttct
    22441 cttgctgttc tgcttcattg cctataaacc tttatgaaag aagagataac atgcctacta
    22501 tccatattgc cggtgattct actgcggcag aaaaagatga aaacaagcgt cccgagacag
    22561 gttggggaga aaaaatctct gcttattttt cacccgagat ccagatcaat aaccaagcaa
    22621 agaatggacg cagcaccaaa tcatttatcc aggaaggaag gttagcccgt ctagcttcac
    22681 agtttcagcc gaatgatttc ttatttgtac aatttggaca taacgaccag aaaatccaag
    22741 aagaaagagg tacgcttccc ttcggtagct atttaaaaaa tctgcagata ttttttgaat
    22801 gcgcaaaaaa agcgaacgtc caaatggtct tactgacatc tgtgacgcga cgagattact
    22861 tagaaaacgg aacattgaat ccagatatac ttggagacta tccaaaagcg atgcgtgcat
    22921 ttgctgagaa acaccatatt cctcttttag atgtgttctc aagatcacaa gaattgttcc
    22981 agaccttctc aaaagaagag acaaaaaaat tctacctgca tcttatacct gatacttgta
    23041 aaaattaccc agaaggacta aaagacaata cccactttag tccagaaggc gctgataaag
    23101 ttgcccgaat aattgttgaa ttgataaaag aatcccgtct gcctcttgct aattatttac
    23161 aaaaaggagt ttgagatgtt tccattaaat ttaggcatcc gtgcccacga tttagatgtt
    23221 cgaaatcgtg aagaaatcgt tcaaaaagta tcacagcttc acttgtccca tatccaattt
    23281 gcaccacaaa aagcatttcc tgaacaactt aaattaactg acatgacact tgggagtgct
    23341 gcctattttg gtgaatactt ccaaaaaaac aatatcgaac tttccatttt aggatgctat
    23401 atcaacctat ccagcaaaaa tcaagaagtt cgtgcacaag cattggcaac tttcaaacag
    23461 caaattgctc tgtgctctgc ctatcaagcc aagatgattg ctacggaaac cggtagtgtc
    23521 tctgtcggtt acacaaaaga aaattttact gaagaagctt atcagatcgc cagaaattct
    23581 atcattgaat tagtcgctca tgcagaaaat tttggcgtaa ctgttgctgt tgaagcaggg
    23641 atcaatcatc caatctataa ctatcagtta gctaaacgtt taatcgatga agtagcttca
    23701 ccaaatttaa aaatcatttt agattgtgcg aatttgatgc ataaagaaaa tcatgctgat
    23761 caggaaaaag tgatccgagg tgccttggac aatttacatg gttatattac agcgcttcat
    23821 ctcaaagact atatcatgga aaatggaaag atccgcatgg tacctgttgg caagggctgt
    23881 ttagatttcc gcccggtact gcattatatc aaatatgagc gtcctctaat gtacgccact
    23941 cttgaagcta ctcctgagat ttatgttcct gaagcaatag aacacttgca gtttatttac
    24001 caagattgtt aaggagaaga ttatggagga acgaatacag aaaagttatc aaaaatatca
    24061 tgcaaatgct tttcagacat tgctgcatct ttatcaggga aattattggc gttttgccat
    24121 gtcaggactc ttttttatta tcaaacatct tccatcttgg ttaatgccga tcgctattgc
    24181 caatgtaatc aatgcagctt catcgaaaga ttcttctcag ttgcaggcca tttatttcaa
    24241 cgcttttttg atggcttgtc tgattggtca aaatatattg acgaattatt ttcatgtaaa
    24301 ataccatagc acttcgatcc gtcaagtaga agctggacta agagcgaccc ttatcaagaa
    24361 aatccaagaa ctatctattc cttatcaaaa agaattgcaa tctggacgaa tccagtcaaa
    24421 gatcatccgt gatgtagaag ctatccaaac gttgtcctct caagtatttg tcagcggatt
    24481 aaatatcgct gtcaatttat tcgtagcttt aggtatcacg ctttataaaa gtcctgttgt
    24541 tttcatgttt ttcttattga ctgttcctct cgccgcattc gttactctct ttttccgtaa
    24601 aaggatcaga cagtccaact cagacttcag gcaagaaatg gaagagactt ctgcaaaagt
    24661 gatcgaagtg atcgaattag caccgattgc tcgagctcat gggttagaaa aacacgaaac
    24721 aactcgctta aataagcatt ttactcaaat ctatgaaaaa ggattccact tagatatcct
    24781 gcaatctgtt ttcggatcag tcagctgggc tagttttcag atatttcagc tgatttgttt
    24841 gattttcact gggatattag ctttacaagg gcgcatccaa cccggcgatg tcgtgatgta
    24901 tcagacgtat ttcacgacga tcgtcaattc cgtttctgga atgatcacgc tgattcctac
    24961 gatttcaaaa ggcatggaat ctatcacttc tattggcgaa ctgttgattg ctggcgatgt
    25021 agaaacttat cacggtaaga aaaaaatcca acatttggat ggaaattttc gttttgagga
    25081 tgtttctttt ctttatccgg actcactcaa accgattatc gatcattttt ctctagaggt
    25141 gaaagctgga gaaacaattg cttttgttgg gccatctggc tctggaaaat ctacactcct
    25201 taacttattg attggattta tccagccgac ttcaggaaaa atttttctag atgatcagcc
    25261 tttggatgaa ctggatatgc gaagtgtgcg aaattattta gccgttgttc ctcaaaccac
    25321 tttgttgttc tccgcttcga tcaaagagaa catcacttat ggcttgaaaa acgtatcaaa
    25381 agaacgttta gatgaagtca tcgaagctgc gcaactttct tcactgattg accagcttcc
    25441 tgatggtctg gataccttag taggcgaaca tggcaacaag ctgtctggtg gccaaaagca
    25501 acgtatctcc attgcacgag cgttgatacg tcagccaaaa atcattttgc tagatgaagc
    25561 aacctcagct ttagataacc agtcagagaa aaaaatccag caagccctga attacctgac
    25621 agaaacaccc actactttta ttgtggctca tcggctttca acgatcaaag aggcagataa
    25681 aatcgttgtg atcgatgaag gaaaaatcgt tgaaataggt acttacgaaa aactgttagc
    25741 tcaaaaaggc tatttctacc gcttgaaaaa tgaatgacaa aaaataggag ctatgacaag
    25801 acttttgtcg tagctcctat ttctgaataa acggtgttct cctgccaact cctcggtcac
    25861 aagtcacaat agtcatcaaa catgagaagc tgttttttga aattgttcct tgtaactcag
    25921 agttaaacgg taggctcacg acctcttggt aaatggtgtt caagagacag cctatcggca
    25981 ataagaagca attttgtcat cgctcaaggc cgaacgtctc tttcacaccc tctgttgttt
    26041 cataaaatag ttttattcgc tgtaaaggtc gcgaactggt gtcatgatga tacggttcaa
    26101 gtcattgatg attgtactga agccttgctc tttttgcatc aagtcattga ttacttcttc
    26161 tgattggatt ttcacagcca tttcttgtgc tttcattgca tcttcgtcgc tgaactcttg
    26221 tccactcatt tgtttttctt gtaattcgat ttgcatcgct tggaagtctt tgaacagttt
    26281 gtgtgcttct tcgtttgctt gtactttctc gtacgcttct ttcaacgctt tgaattctgg
    26341 taattcacgg atctcacgtt cgatttgatt cgcgctatcg tagatgtttg acatgttatg
    26401 ccctcttttc ttttagtagt tactctctat tgtaacatgg ggttattcgt tttcaaaggg
    26461 gctactctcc ttgatatttc cgccagaggt ctttagccgc ttcaccaatt ccctgaacgc
    26521 cttctttcac catatcgccg aagtttttca gcccttcttt tgcttgttca ccatattgat
    26581 tcaagttatc ttgccaattt ccagactctc cattagaatt tcctgtgttt ccaacttgat
    26641 ctgcagctac cacttgtcct cctgtggcat aggcatctgc tacactaaat cctgtttttg
    26701 aagtatacgg aaggatgcct tctgccgctg atttgaagac tttcccgaca acatttccac
    26761 ttgtcccttc caaatagtgc agcttgctgg attcttcgta acccatccat gtcgaaatca
    26821 ctacgtctgg cgtgtaaccg atcatccatt ggtcatttgc ttttgtggca tcgaaattag
    26881 tttctgtggt tcctgttttc cctgctatcg tataacctgc aggattcgca gcagccgctg
    26941 ttccatttga aaatgtacca agaagcatgc tggtcatttc atcggctgtt tcctttgata
    27001 tgacctgttt tggttttttg tttgtgttat cgacgatcac cgctccagtc gaatcaacga
    27061 ttttcgtgat aagatgcggc gtatacatct gaccatcatt ggcaaatgca ctgtaagcac
    27121 ccgccatgat caatggagat actccttttt ccagtccacc aagggctaag ccataatact
    27181 tatcagattt tgctaaaggc aggccgaatt cttctgcttt atcatatcct ttttgtaaac
    27241 cgatctcatg caaaagccat acagtaggca aattcaaact ttgtgcaaca gcttgataca
    27301 tcggtacttc tccttggtat gtcccgtcaa aattatgcgc atcgtaataa ctttgcggtt
    27361 cgtctttcaa gatactggaa ggcttgtatc cagcttccag tgctggtgta tatacgctta
    27421 atggtttgat cgttgatcct ggtgaacgac gcatctgtgt agcaaagctg aatcctctaa
    27481 agacatgatc tcctcttcgt cctactagtg cttgtacacc acctgtattc ggatctaaag
    27541 ctactgaagc agattggacc atggcaccat ctgaagcatt tgctgggaat aatgcactgt
    27601 tttgataagt agcttctaat tgcttttgat aatcctgatc taaagctgta tagattttat
    27661 agcctttatt catgacatct tcttcatcaa gaccatactc gttaactgct tcatcgatca
    27721 ctgcatcaaa ataataagga taacgataac cagaatctga attatcgtat gtgtcattaa
    27781 gatacgcgct gatatctgtc tggctttctg cttgttcttg ttcttttgtg atttttccgt
    27841 tttcttccat tacacttagt actgtgtttt tccgatcatt cgcatttttt gggtgatcga
    27901 tcggattata aataccagga cctttcagca ttcctgccaa agtagcagcc tcagacagcg
    27961 taacattcgt tgcatctact ccaaaatact ttctggaagc gtcttggaca ccccataccc
    28021 cgttgccaaa ataggcattg ttaagataca tggtcaagat ttcttctttg ctgtacttct
    28081 tttcgatctc gattgccaaa aataattcct tcgcttttcg atcaaacgtt tggtctaatg
    28141 tcagatacgc atttttggca agctgctgag tgatcgtact tcctccgccc cctgatgttc
    28201 cgccagacaa gaccattcgg actgctgcac gggcaatccc tttgatatca aacccgtgat
    28261 gctcgtaaaa attcctatct tctgtcgaga ttactgcatc ttggatatag ggagaaatcg
    28321 cgtttaattc tacatatgtt cctttttggg cgtacagtgt gccagcttct tcgtttttct
    28381 tatcataaat gactgtcgat tggcttaatc ctgattttaa cgtttcgaca tttgcttgtt
    28441 ttgctaaaat aaagaggtag atacttgtca ctaagacaca gatcaaacca atcagcaaaa
    28501 tcaatttgtt cacatgatat tttttccaga tgcgctttcg ccatcgatgg aattgtccga
    28561 gatatggtct gatccaacgc caaaaactga tcaaagcagc ttttatcttt tctaaaatgc
    28621 tttgaaaatc catttgcttc ttctcctgtc tatttgattc aatcgtctta ttttaccata
    28681 gtgaaagagt gttttcttcc tgcttaagtt gtagttcaat atgttttttt acgttagtgc
    28741 aagtagagta acataagaat gaacagaaaa atgtaagttt tttcttaaat atgttttaaa
    28801 aatggtacaa ttagtctgcg attgcactga aaggagtaca cttgtgaaaa tcacgatcac
    28861 tttacctatg aaccatcctg aaacaacaat tcgcgacttg cttgaaaagg aatggttagt
    28921 tcctagaaag gttcgacact ttttgcgtat acgtaaaaac gtttggatca atcaacaacc
    28981 tgctttgttc catcatgaag taaagggcaa tgaccagatc acattgttat tcgaagaaac
    29041 agattataat tatcaagaag ttcaattagg agatgcgaag cacatccgtg ttttatatga
    29101 agatgagcat ttgattatag tggataagcc tgcaggaatg aagactcatc caaatgaacc
    29161 gacagaaaac agtaccttac tcaatcattt agctgcttat ctcgacacta aacagcaacg
    29221 accttacgtt gtccaccgct tggacaaaga aacaagcggt gccgttttat ttgcaaaaaa
    29281 tccatttgtc ttgccgatac ttggaagaat gttggaacaa aaaatgatct atcggagata
    29341 tcaagccatc gtatggggag aaattgccaa agatatgacc atcaccaata aaattggacg
    29401 agatcgccat gatcggagaa aaagggtcgt agatgataaa aatggtcaga gcgccttgac
    29461 acatgtcact gtcaacaaag tactttctga acaaacacaa gtctattgtg ttttggaaac
    29521 cggacgtaca caccagatca gagttcattt agctcataag ggacatccga tcgttggaga
    29581 ccctctctac caaaatagaa cagctgaacg actgatgctc catgcattag aactgcacat
    29641 gatccatcca tttactcaag aaaaaatagt cggtaaagct ttacctggat tatgggaata
    29701 gaaataaaaa agaacagagt cttatcagca gataatgata agactctgtt ctttttgtgt
    29761 aatttgtctg cttacttttg atgttcgtgt tctgctaaca gcaaactacc gataatccca
    29821 ctttcattcg gcagtcccca acgaacgata tattcactta cttgaggtgt ttccatataa
    29881 ccacccatca attcaacaaa ttgctgacgg attttttgaa ggagatgatc ctgattcatt
    29941 accccaccgc ctaaaataat cttttcaggt gctaacgtca acgtatagtt gatcagtgct
    30001 tgagcaatat aataagcctg aatagcccaa acaggatgat cttgcggcag atcttgccct
    30061 ttgatccctg tgcgtgcctc aatagacggt cctgctgcta atccttctaa acaatcttta
    30121 tgataaggac aagtaccttc ataatggtca tctggatggc gtttcaccca aatatgtccc
    30181 atttcaggat gtgcgatccc tgaaaaaatt tcttcattga tcacgacacc tgcaccgatt
    30241 cctgttccca cggtaaggta aatacaacta ttttttcctt gtgctgctcc ttgcttcaat
    30301 tccccatatg cagcagcatt gacatccgtt gtccaagcag caggaatatt gtagcgttcc
    30361 ttgattgtgc caagaaaatc gaattgtgcc cacccttttt tgggagttgc caaaacgtat
    30421 ccgtaattat cttttgtttt gtcgatacca atcgggccga atgagccaat cccgattccc
    30481 ttcaattcat aacgatcaaa aaattcaaat acctgatcca atgtttcttc tggtgttgtg
    30541 gtagggatac ttaatttttc taaaatttct ccaccatctg aaaccgcaca cacaaatttt
    30601 gttccgcctg cttctattcc gccatacatt cgttttcctc ctcgaatccg attgtccgaa
    30661 tctcataagg ttggattatt gggacaaccg cttgcttcgt tggttcttca agcagattca
    30721 atatgacagt ttttccattg tctttagtta tttccaattt ttctaaatga ctagacatat
    30781 tgaaacctct tactactact ttatcactaa acttgctgcg tttcaaagct gtaattgcaa
    30841 acgtttcact ttttatcgtt aaatattgtt gttttgaaat caatgttcct tcatgatgtt
    30901 tgatttgttg agtggaaaaa ggaatctgtg ctgcgtatgc atgcaaataa gtagagaatt
    30961 tttcttctgg tccatgtagt tcaatgctgt aattgaaccg atgctcacct agacactgtg
    31021 cttctggtgt tggaaaatat ccccaatcgc ctagttctcc cacactgcga agtagcgtca
    31081 ctgcgatttg tccgtcttct gttacttcat attcattcaa accaaagttt ccgactgtta
    31141 caccgtactc ttcatcatga atattgacaa atgcttgctg atgttgcgga ttcgtggggt
    31201 tttcccaact tttagacaca tggtttgggc gcttcaccac ttcaaaaata ctatctgctt
    31261 cgtgatgttc cacatgtaac tttgtaggaa acaagacacg taagcgatga tctttcatct
    31321 gattgtcgag agtcgtttca aagtcgattt ttttactatc ttttctgatt gtcatgattg
    31381 tttttatttg aaggattcgt ttttctttgg atcgttctgc ttttcgataa cgaaattcca
    31441 caaccatctg ctgttctttt tctaaacgct cgtctgcaga aacagggatt tccatttcct
    31501 gtagaatact tatttttgct atttccggtg tatctactaa tacttttact tcagagtttt
    31561 ctttgttact ggataggatt ggctgatcac agaaaggttg tttaaagata tactcatttc
    31621 ctatatcgcc gatatcttca aaaatatgca gattattcaa ctttcgtttg tttttgcgat
    31681 cttccattgt aatggtacca tttttttcaa tcgtcaaatg tagagggccg ttttcgatga
    31741 ttcgtccact ctgatgaatc attgtttcct tttcttctgc tttcgcttcc ccttctacaa
    31801 gcgcgaatgt ttcccaagaa aatgctggca tgttttctaa tggtaaagtc actttgatca
    31861 ttcttgccat atatggcaca cggaaacggt ctttcggcaa atcataacca aattggacag
    31921 tttcttcaga taaaatagct ggtatagtgg ccccactttt tgtttctaca tgatacttac
    31981 gtttaggcaa attttctaac tcttgatata gttgttcagg tattccttca gcgaatcttt
    32041 ttctttctaa ttcgatggtt atttctgcct caccagtttt atccattcct gcagtattta
    32101 caatgacaaa tggaaagctg tcttttggga atccggtcgt atcgattgct gcggtcagct
    32161 gttctaagga atcttgtgca agatactttc caacttcatc tgctttttca aaacgaggta
    32221 tcatttcccg atggacagaa tcgactgaac aaccgcaaat actgtcgtga ggatgatttt
    32281 gcattaatgt cttccaagca taatctaatt gatcatgggg atagtttcca ctaacttcat
    32341 aagccatcgt cgcaagtggt tctgtaatat tttctagctg tcgctggacc ttggtattcc
    32401 attgttttaa gtaaacccga gcagatgctg tattggctaa agtataccag ccatccgttt
    32461 cttgacttgt caattctcct tctactgagc ctaagtcttc tggcacatct ttttgaactg
    32521 cttccagata gtcagtaaaa ttagaatgaa taaactcgta atctggaaac agttcatttg
    32581 cgagatggat tgcttttgat atatcttttt gtaccggttg atgatcaaca ccattcatca
    32641 tcaataagtg gttcgtagag gcatattgtt ctgcatccgc taatttttgc ttccaaaagg
    32701 caagagctgc ttctttttct actggaatct cattcccgtt gctataccaa ttggcaaata
    32761 gcagaccaaa gattgctgtt tgatcaggtc ctttccacca catctctgag tattgggaag
    32821 aatagttttc tgcttccaaa acttgattat caaagccaat tggttttaca ccacggccaa
    32881 acgctgctgc tgaaatacca gcttgtttca ttaattgagg cgtctgtccc atatttccaa
    32941 atgtatcggg aaaatagcct aacatgacag gggttcccca tttacggctt tcttccatgc
    33001 caatcagcat atttctcacg ttcgattccg agctgataag aaaatcatct tgcaagatat
    33061 aaaatggtcc aattctcaat tttccttcat tgattgcttg ttggattgcc tgtctttttt
    33121 ctggccttac ttgaagatag tcatctaaaa taatcgtttg cccatccaaa tgaaaactgt
    33181 tgaaggacgg atcaacttca aatagctcta gtagatcgtc tatcaattca atcagtcgca
    33241 tgtgatgctg ttcgtaagcc atgtaccatt cacgatccca gtggctatga gaaatgatat
    33301 atactttctt tttcatttac gatacctcct acttttctac tctaatatca aagtaatcca
    33361 tgactaattc gcaaaacatc atatttgccc aagaaaacca ttctctcgta taattttcag
    33421 gattgttcac atcgaatcct tcgtgcataa ggtgtgttcc tgcgtcagtt gctacaagta
    33481 aattcaatat ccgctctttt tcagatttgt ctgacgttgt cattccttcc atagctaatg
    33541 caatcggcca aacgtatttt tctggcgtat gggaggatcc aattcctttt gcgtactttc
    33601 cttcatagaa atatggattt tctttactca acaatgttct tcttgtttgc agataatctt
    33661 cctcttgttc agaacaatat cccaagtaag gtgcggcgat cagattgggc acattactgt
    33721 catccatgac tgtggcgttt cccattccat ctacttcata tgcataaatc gtttgccctt
    33781 tttgattaac cgttcgtccg tgattctgaa tcccctcttg gatctctttc ttcaatttct
    33841 gtgtttgctg tacaatttct ttatcatcga gtatcgtttg aaaaatttct tccacataac
    33901 ctaacacgac caccgcaaac atattggatg gtaccagata tccataacgg caagtatcat
    33961 cgctaggacg gaaaccagac catgtcattc ctgtaaaagc tgtttttgca cctcgcccgt
    34021 cattgatcag cgtatcttct tttcttgtcg tgtctcgtac aaatgtataa ggagagtgtt
    34081 catgatcttg ctctgttttg aacacgtcca agattttttt gataccttca ataaaagatt
    34141 gattgaattg atcagttttt cctgtatttt tgtaaagaag ataggccaac tgtattgggt
    34201 agcataaaga atcaatttca tattttcttt cccagatcca atcgttcatt tttgtatgat
    34261 ctgtttggtg gccagcaccg ttagcttctt cgttgaaggc attcgcatat ggatcgatat
    34321 tgatataaaa aaattgcttt ttgactaacc cgctgatcat gtcagctaat tcctcatctt
    34381 cttttgcaat cactaaataa ggacgaactt gtgcagtaga gtctcttaac cacatcgctg
    34441 gaatgtctcc cgtcaataaa aaggtggttc cgtcattttg ctttttgact gttgtcaaca
    34501 gagtattggc aaatgctgct gtaaaattct ttgcccagtc cgcatggata tccccacatt
    34561 tttgtgtgat atcttccata aatttctgca ccgattttgg tatatcttta taagccacta
    34621 ataaaacctt ctttctattt gatatatctt taaagattat acttcataca gccaattatg
    34681 tctacgcttt caaaaaatat ctttttattt actttttcat ccattatggt attatttgaa
    34741 tatgatatat cattaagagg tgtttatatg aatcaaccat tgtaccagac aatatttaat
    34801 gatttgcaaa cggctatttt aactggtgaa ttacctgtag acagccaact accaactgaa
    34861 aaagaacttt cacgtaccta taaagtaagc agaatcactt ccaaacgtgc attgactgaa
    34921 ttagagcaat taggacttat ttatcgcgtt cgcgggaaag gcagtttcgt taaatccgct
    34981 tctccggaac agattcttgc ttctcctaca aaaacacgac ggattctgtt tcttcttcca
    35041 tatgtcgctg atttgtctgt tggtgatttt agcaagggat tgaaccctgt gatgcaagat
    35101 aaacagattg atgtcatgat gacgacgctt gactttctac aaaataaaac agcaaaagag
    35161 ctaatcaatg aatttgacgg attgatttat tatgctcttg atacagaaca acatcttgac
    35221 ttactttttg agctttcatt gaaagaattc cctgtcgtca tattagataa aaaaatctat
    35281 gagttacctt ttcctaccgt tctttccgat aatttccaag gcggtgcgct tgctgcctct
    35341 tatttgatcg aacagggaca ttcaaaaatc gcttatttgt ttggtacgca gactcatcca
    35401 caatccgttc gacagcgtta ccttggttac cttgaagcat tggacaaagc tggtttgact
    35461 ttccacactt cactggatga caaaagcgcg acattagatg aattgctttc ttatatcact
    35521 aagtatgaag taactgcttt tgtttgtgaa aacgatgttg tcgctatcca gaccatgaat
    35581 ctcttgagac agcatggtta tcatatccct gaagattttt caattatcgg atttgatgat
    35641 atccaagcag cagctcttgt tgacccgcca ctgacaacca tcgcacaaga ttttgaacag
    35701 ttaggtaagc ttgcgggaga tgctttggtc acttggttag agacaaaaga tcgaccatcc
    35761 gatagtaaat ttccagtttc attcatcaaa agacaatcaa caaaggagaa ataaaatgaa
    35821 tatcggtcaa atagatacta gacatgcaac agcgaatcag ccaaatttct ctaatgggaa
    35881 ctgccagcct tatactggcg ttccttttgg gatgaattat tttgcaccgc aaactacgga
    35941 tcaaaacggc agctggtggt ttcatcctga tgaccgcgtt tttcaaggct accgtcttac
    36001 ccatcaacca agtccttgga tgggtgattt cagtcatatg ctgtttacgc cgatcaatgg
    36061 aaaactacag gagaacaccc ttttccatgc tcaaagttct taccgcccag aagaaagtat
    36121 attttgcccg actcatctgt cgatctgtca attacgttat ggcatctgtt ctacattgat
    36181 acctagcatg tatggcggaa tcttatctat tgattacagc aaaaatgaca gcggtttact
    36241 tttatccttt ccgggacgcc atcagctctt tgttatagat ccttacacag tggaaggaaa
    36301 aatcacacat tttgctggtt cagaagatcc tgatttttct ttttatttta tattgagatt
    36361 tgaatatcct ttaacaattg atgagttagc tgtttccaac aaaaatagcg actcgatccc
    36421 gttgtatttt gaacagacaa aaaaacaaac tatccgattt gggacatctt ttatcagctc
    36481 ggaacaagca gcttataacc tggaactaga acaaaaccaa agcaaagaga cttaccttgc
    36541 tcacagtcaa gaacaatggc agtcctattt tgatcgtata cagctcacac accatgatca
    36601 acaacaattg cggacgtttt atcataattt atatcgggtg tttttatttc cacaaacatt
    36661 ttatgaaatt gatcctagtg ggcaaaaaat ccactatgat acgactagtc gatctataaa
    36721 acctggtgtt ctctatacaa ataatgggtt ttgggatacg tataaaacgg tttatcctct
    36781 ttattctttg attgctgtag aaaaatacga agaaatgctg gaaggttttt tgaacagcta
    36841 tagagaaagt ggctatttgc caaaatggct gtctcctgat gaacgtggac ttatgcctgg
    36901 gacattgatc gatgcggtca ttgcagatgc tgctgtaaaa gatatccgac gagacttgat
    36961 gcctgaattt ctaacggcaa tggaaaaagg tgctacggtt caaagcaaac atccaaatta
    37021 tggacgccaa ggaacagaag attacttgac atatggctat gttcctaatc actaccacga
    37081 atcagtcaat cacacattag actatgctta tagcgatttt tgtattagcc aagttgccaa
    37141 ggtactagaa gaagaggaaa tgacgaagaa atatcagcag caatcattga actatcaaaa
    37201 tatctttgac tatgagtcag gatttatgcg ttcaaaagat aaagatggca agttcagaga
    37261 accattttca gctaatcgtt ggggacaaga ttatgcagaa ggaagtgctt ggcaaagcag
    37321 ctttgctgtt tatcacgatt tttcaggact gatcggaaaa tatggtggca gtgagagata
    37381 taaagaaaaa ctcattgagc tgtgcaatca gcccccaacg tttgacccag gaggatatgg
    37441 ttttgagatc cacgaaatga gtgagatggc cgcgatagaa tttggacaat tagctatttc
    37501 aaaccagcca agttttcact atccttactt gttcagttat ataggacaac ctgaaatggc
    37561 acagccactg cttaaacagt tgatgactca gaccttcgac gattctccaa tgggttaccc
    37621 tggagatgag gacaatggaa gtatggccgc ttggtatatc ttcaatagtc tgggatttta
    37681 tcctgtcacg cctggaaccg gtgaatatgt tatcggtatg ccattaattg acaaggctgt
    37741 tttgcttttg tcaaatggaa aggaattgac gattgaagca acgcctaatc ggccgcagca
    37801 acaatttatc cataaaatca aacggatgga caaagaatat acgaaattat attttaccca
    37861 tcaagatttg ctgaaaggcg gcacgatctc ttaccaatta gggatcatcc ctcaccctaa
    37921 gaaatatcaa gcaaaagatt tgcctttttc cttatcaaac tataattaac aagaggttgt
    37981 gaaaaagctg tcctgcatca agtaataaga acagccaagc aaaaatagat cctcatattt
    38041 ttcgtttggt tggtcttatt accgcagatg caagcttttg aacaccgttt attgagaggt
    38101 tgtgaaatca gcgttctgac ctgagtatta gagagacaaa tggcaaaata gttcctcata
    38161 ttttgccatt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tagtggagag
    38221 gtcgtgaaaa agctgtttag tttcgagtat taagaaaaat tttgtgaaaa tggctttcca
    38281 catttttgca taaatttggc ttaataccga gaaactggct tttgaactcc gtttatcgag
    38341 aggtcatgaa aaagctgcct tgcctcaagt aataagaaca gcccaaaatt agatttctag
    38401 acaatttttt ataagttatt tcattacatt ggctttttct tttatgattc tccactgttt
    38461 tctcggtact ctttagggga tctgccgacg attttcttga ataatttaga gaaatacgtg
    38521 gtgttgttgt agccaatctc acttgctatc tcattgatgt tttgattact gtgcaaaagc
    38581 agttgtttcg ctttttccat acgtaaatgg ttcaaataag ctgaaaaact ttttttcgtt
    38641 tcttttttga acagctgtcc tagatacatg acatttaaat gcaggttttc tgacacttct
    38701 ttgagtgtaa gtggttcttg ataatgctgg tgcaggatta cgattacttt ttccacattg
    38761 tcactgtact ttttctgtct ctgatgcttt ttgatgaatg acagaagtag ctgctgaagt
    38821 tcttgcaccg tttttgcctg atggattttt tcgattcctt gtaaatattc ctcatcttcc
    38881 agatcaatca attcccgttg aatctccata aacagtaaaa aactggaata tcgtatatct
    38941 tccggcatca tggctgctaa ctgaaactgt tcaaaaaaat cagtgatcat tttttgagcg
    39001 acttctaatt gtttattttg cagcacgcgt ctgaaacttg aaaaatcgat ggtttgatct
    39061 tttgtttctg cttgtactgc gtaaaaaaca tgctcgtctt tatctccata aaattgatgc
    39121 aactgtagat tgtctttcgc ttgttggaat gtttcaggga ttttgtccaa agaatctgtc
    39181 tcttccccga tactgatcag ccattcctga tcaggaaagt tttcttgaac aaaacaacag
    39241 aagccatcaa cttcatctgc ctccaacaac aacgtgatca atacacggtc tccgtaattt
    39301 cgttgatagt aaaagatttg ttgccgttct tgcaaccatc tattgataag agtatcatga
    39361 gttcttgcca gttgaatcaa tactatccta tgctgcttct cacttatttg tcctattatt
    39421 tcttcttcac ttatttcatc caattcttca ttcaaccatt gactgaataa cagttcttga
    39481 tagatttctt gttgattttt ttgttcattt tgctgatcta accgtgtttt gattttcttg
    39541 aggctttcaa ccaattcgaa cttattcacg ggtttcatca aataattcac ggcgcctaat
    39601 tgcatacctc ctttcaaata atcgaattct tggtatcctg ataaaatcat aaattcaaaa
    39661 ttatgacgtt ctttttgagc cgcttcaata aattccagtc catttatttc tggcattgtc
    39721 acatccgtta ctactaaatc aatctgtcgc tgttcaagta cagctagtcc ttctttggca
    39781 ttctctgctg ttgctactat ttgaaagcct aaactttgcc aatcaattat cttttttaac
    39841 ccattcaaaa tcatgtattc atcatctacc aataacactt gatacacgct catccctcct
    39901 tgaatgtaat agaaacggtc agtccacctg tctcattatt ctcaagcgac atataataac
    39961 tgctgccgaa gctggcacgt aaacgttcat tcacgttttg cagaccgata gaaccgtgaa
    40021 gttccacttt aggatgagac agtttttctt caatctgttt tagccgtttt tcagtcatcc
    40081 cttttccatt atctttgatg atgatcctta cccgtttgcc ttcctgcaag actttgacac
    40141 ttagcgcatt atcgaatcga gtaaaatcaa taccgtgttt aaaataattt tcaactaatg
    40201 gctggatcac aaatttaggt acttcgatct tttccaaatc aggatcgatc ataaaatgat
    40261 aggctactcg attaggataa cgcatttgat acaaatagac atatttttcg caaaagtcca
    40321 gttcttcttt taaagtgatc gttttctctt gattcgtatt gtttcgaagc aaagcggaaa
    40381 acgcatacac aacatctgct aattcttcac ttccttcgct gattgcatac attcggatat
    40441 attctaatgt attatataaa aagtgtggat tgatctgtgc ttgaagcgcc cgcatatgtg
    40501 cgtcttgctg tttgatttct aatttgtaga tgtcttctac aaactgattg atgctatcca
    40561 acatttcgtt gataccgatt gaaagttcct tcagttcata ttccgtgttt gttatgtcga
    40621 tccgcgtctc taaattccct gctgctgttt gatccatggc ctgcatgacg atagatactt
    40681 gctgtgaata tcgtttgaat gttttataaa gaaagataag cagtatattg tctaaaataa
    40741 tgataccaat gatcagcggg gcaagatttt ttcccgtttc gatttttaca ctttttttat
    40801 ctagtacagc taatatacga taatcatcag acagttcttg gtgttgaaca aaattgtttt
    40861 tttccagatc gtcaatcggc aattgtgaat ttttcttcag actctctgtg atgatcattt
    40921 cttgtctttc aaacgtttct ttagctattt tattatcatg gaatgtgtat agtcgatttg
    40981 tcgttccaga aatcatgtat aaagagagtc cattgaatga cgttagattt tctaaaatca
    41041 tatctagttc tttcttttga aaaccaataa aaatacttcc tgactcagct cctccttgtg
    41101 tgataggcaa cttgatataa aaggcgtcta gtaattttgg tgtccccttt tttatttccc
    41161 cacctttgtt ttctctagaa gattcataat actccggtag ttgattcaac acgatatata
    41221 tcgcacttag ttcttcataa tttgcgtaga gatctttgat ttgatttggg aaagaaacta
    41281 attcatcggt actgttttgc tgttcgtata catacatcag atactgatct atgggttttg
    41341 ttaagtaggt cgtcacattt tcgatctttt cggaattccc tacaagctgg tttttgatga
    41401 tcctactcaa ggttgtttta tcattcagca ttctgcttgt gctttgaacg gcatcacttg
    41461 tcatgttttc tgcctgtttt tgattttgtt cccaagtatg gatactaaaa ataacggtag
    41521 cagtcatcgt tacaccgatc atgataaccg cgtatttccg caacagacga tttagtaagg
    41581 ttccttttga aaatagaatc cgaaacttat tcataacttt ccaactgttt atctaattct
    41641 tcacgccaat gtgttgtcat cgtaccattc caaaccgtca aaagaccaat gacaccaaac
    41701 aggatcaatc ctttgaattg ccaagtcacg cctaaaatta taccgctacc aataattatt
    41761 tttagaaaag acgaaaagct ggaaaaaacc gaaataaaac ttagctttag cagattagga
    41821 acagagatcg tatattcact atctaaaatc atactgtatt gataagtagc aaataggcag
    41881 agcaaggcaa aaagtaaaat aaaatcaata gctaaaaaaa tgagcccttt gatttgaaca
    41941 gataaatata aattgtaact caataaagca gtaccagata aaaataaact aaatagcaga
    42001 ttgcctctta aaaaatttct tttatatata ttccagcctc tttttattgt gatttcttta
    42061 tactcgaatc cgtacaaata aaatagttca ttgactgttt tccatgccgc acctaatcca
    42121 aagatgatcc cgccggcaaa tgtatatatc cagaaataca aggttagttt tataatgacc
    42181 cagatccgga taaataactc ttccaaaacc ttccctaaca tatcttctcc tccaaacatt
    42241 aagtttatac tttctcatta tacaaaaaaa ggttgggcaa tcagcacctt gacctgatta
    42301 ttagagaaac aaacggaaaa atagttcctc atattttgtc gttttgtgag cgaataccga
    42361 gggttagctg attgaacacc gtttaccaag agtttgtgaa atagccgctt agtttcgagt
    42421 agtaagaaaa attttgtgaa tatggctttc cacattttta catatattta gcttaatacc
    42481 gagaaactgg cttttgaaca ccgtttattc ggaacaagag gttgtgacac gtcttttgtc
    42541 acaacccctt tgtctttatt cattattatt cttgtcggaa ctcatcatat tgtttttgca
    42601 tttctttcaa taccttatca tagccagcct tgtccaaagc gtctttcaat ttcggtaatg
    42661 tttcatctgg atcaacagtc cctgtattca atccatctaa atattgattc atgacattag
    42721 aaatattact taattctgtt ttgacactgt cagtgttgaa gctgaatcct aaaatcggtg
    42781 aagtttctgc atcagcaatc gattgatcac gtttggcaat catgtcatcc gtaatagact
    42841 cttgtgtata tagaatcttg ttgtttcctg tattccaagc agacatatgt gtatttggct
    42901 gataaccatc tagcaatttg attttatcat ctgaaccatc gactttttcc catgcttctc
    42961 cctcgatccc ccaaacaagc ccattcaata attctggatc actgttaagc agccctagaa
    43021 gttctactga tttttcttta ttttttgaag tatttgatac gacaaaattt gccatttgtg
    43081 cttgagctgt agattttagt ggaacagtaa ttgcttttga gacaagttct tgttttgctg
    43141 catttgtcaa aattgtatcg ccataatcat acggtccttg tgtttctcca cgcattagcc
    43201 aagtatttcc ttctagtgga taatccttat tgctcgttgc agcgtcactt ggaatgagtc
    43261 cttgtttgta ccagctatgc attgtacgta acagtccgat atacgtttca ttatcgtatt
    43321 ggttgatgat tttcgaatca tctccatcca gatcaatagc aaatggtaac gtattcccta
    43381 aaggataatc aaagttccct tggactttga agccttgtcc aatggcaaaa gctgccgtgt
    43441 ttggttcttt ttcatggaat tccttcaaga ctttttctgc atcagcgtaa gattggattc
    43501 catcaattga aagatcgtat ttatctagta aagctttgtt aaaagtaagt acttgttgag
    43561 caaagacatt tccattgact gggaaagcat ataattttcc attgaccaga tttcctttaa
    43621 tatatgcttc atctaaatca ttataagctt tttcagcgta cttaggcgct aattcagtca
    43681 aatcagcaaa ggctcctttt tgggcattgg aaacatagtt gttcgcaaag gcgatatcat
    43741 aattttcccc ggaagaaatg atgacgttca ttttcttttc gtaatcgccc cagccaatgt
    43801 aattgatatt gacttttaca ccgatctctt tttcgattcg tttgtttgct acttccatca
    43861 attgatcgaa attatctggt ttatctccga tttgatacat ctgcaaagtg tccgaattgc
    43921 tagcttctgc ctggtcttta gaaccagaac ctccgcatgc tgctaatgtt cccaacaaca
    43981 acgctgaaac acctgtaaag gctagtttct tccataactt catttttctt cctcctaatt
    44041 ttatgattta tatttttgtt tctttattct tttactccgc cgattgttag acctttgaca
    44101 aaatgcttct ggaaaaatgg atagctgatc gcaataggca acgtcgagat gactacgatc
    44161 gccattctgg cagattctcc tggaactgag gctaatccgc ctgtcaattg gcttcctgct
    44221 cctgaatttt gtgtcagata ttgaatatta ctttggattt tcatcaaaag atactgtagt
    44281 ggaactagct tatcatcttg gatgtatagt aaagcattga accagtcatt ccagtaaccc
    44341 aatgcggcaa ataaactgat tgtcgcaata cctggaacag ctaacggtaa aacgatctga
    44401 acaaatattc gcagttcgct agctccatcg atccgtgccg attcaataat cgaatcagag
    44461 accgaacgtt taaagaatgt gcgcatcaca ataatattga agggactgac agccattggc
    44521 aagatcaatg cccaaatcgt atcttttaac tgaagaagat ttgtcataac aagataattg
    44581 gccaccatcc ctggtgagaa caacatcgta atcaaacaaa aaacggtaaa aaaacgacgg
    44641 aatggaaagt ttgaccgtga aatcgcataa gcatataaag aagtagccgt gctattgatc
    44701 agtgtaccta aaacagtaac aagtacagtg acgaaaagcg cttggaaaat tttatcctgc
    44761 atctggtcga acaagtacgt ataaccaaat atactgaact tttctggcca aaaactgtac
    44821 ccgtgagtcg acaatatgga ctcatcggta aaagagatgg cgataacaaa tataaatggc
    44881 aaaatacagg aaatagcaaa gagtgcaatc attatattag agaaaaaatt agccgtctta
    44941 ttgaaagagc ggacttggac tctctccact ttcttttttt tcattttttt cctccttaga
    45001 ataatgcaga atcgctatca aaacgtcggg cgatcgtatt tgtgatcatc aacaagacaa
    45061 agccgacaac tgattggtaa agtcctgcag cagccgtcat accaaaatct cctgtggatg
    45121 tcaggccatt gtagatatac gtatccaaaa cttgagtcac atcatataat gcaccggaat
    45181 tcctaggaat gttataaaac aggccaaaat cagctcggaa aatgtttcct acggctaaaa
    45241 tcgttaaaat cgtcattagt ggaataagtt gtggtatcgt cacatgtttg atctgctgcc
    45301 atttgctagc tccatcaacc atagcagctt cataataagt cggatcgatt cccataacag
    45361 atgcaaagta aataatgctg ttataaccaa tccctttcca tgtaccaatg aacaccaaga
    45421 taaacggcca atatttcggt tcattatacc aattgacagc ttctcctcca tgtccagtga
    45481 tccactgatt gaatattcct ttgtcaggac ttaaaaaagc gtaaacaaag taactgataa
    45541 tgacccaaga tagaaaataa ggtagtaagg acatcgtttg ataaacttta acgagtcgtt
    45601 tatttctcaa ctcgctcata atgattgcaa atacgactga gatcagcaga ttcaaaagga
    45661 taaatgctac attatataaa attgtatttt tagtgatgag aaatgcttga tccgaagaaa
    45721 ataaaaattt gaaattttcc caacccaccc aaggactttc cctcaagcta gccaagaacc
    45781 catctgctga aatatgaaaa tttttgaatg ctacgacatt cgccattaca ggtatgtaaa
    45841 agaaaaaaat catccaaagc atacccggta cagccatcag gacaagtgct ttataacgcc
    45901 atagattcat aaaaaaatga ttgaacccct ttcgtttttt catctaaaaa cccctttcga
    45961 ttcattcgca acgtaattat agcgctttca ataatgagaa taaataaaca aagtataggg
    46021 aaaatgaaac aaagtatagg agaggttgtg aaatcagcgt tttggcctga gtattagaga
    46081 aaaaaacggg aaaatagttc ctcatatttt gccgtttttt gagctaatac cgagggtcag
    46141 ctgattgaac accgtttatc agaggttgtg aattcagcgt tttggcctga gtattaggga
    46201 gatcgtgtcc ttactatcta actctgagtc acaaggaaca atggggactg taacaaaagt
    46261 cttgtcacag tcccttattc cgaacaaacg gtgttccaga agtagcttct acggaaataa
    46321 gccgaaattt cacaaaaaag ccatccgaaa gtcagacgga caagtctgct tttcagatgg
    46381 cgctacaact actctgctta ttcttttagc tatccattca attatttttc tctcacttgt
    46441 tctagctctt ctttggtcat gggtcgatat tgccctttat tcaaatcttt aggcagccaa
    46501 aattttccca tacggattct ttttaaatat aagacttctt ttcctactgc tttgaccatt
    46561 cgcttaactt ggtgaaactt tccttcatgc aaaatcagac ggataattga agtttctgtc
    46621 tcttgatcta cttgatcaat ttggagtttt gccggcaatg tctgctcatc gccatcaata
    46681 atcagtcctt ctgcaaataa acggatatct tcttctgtca ttataccgct aacctcagct
    46741 agatattctt tctccacatg ttttttaggt gatagtaact gatgggcaaa caccccgtca
    46801 ttcgttaaaa tcaagaggcc ctctgtgtct ttatctaatc ggccgactgg aaaaagatct
    46861 tcccgataat cctggtcttc caataaatcg attacggttt gatcatgatt atcctgagta
    46921 gcagaaatga ctcctgcagg tttatgcaaa atgtagtaaa aatctttttg atacgtaatg
    46981 atttctccta aataagtaac cgcatcttcg aattcattta cttgcgcttt atcgcttttc
    47041 accacttgtc cattgacttc gatcgttcct tttttgatta atcctttgac ttctttgcgg
    47101 ctgccaagtc ccatatctgc taaaaactta tctaaacgca tgcgtttccc ccatttcaaa
    47161 agagcatcaa tctagctctt ctgattcact tattttattt ttaatttatg tcgtaaacgc
    47221 gctattcctg gtcctagtag tctttctgcc aagcggattt tcaaagctaa ataaccatac
    47281 actaaagccc ctatacctgc tactacaaga atcaacaata gagactggaa tttgctatct
    47341 tcgtttaaaa aagcaccaaa aatcatcttt gtgatccacg aagccaaaag cataatcaag
    47401 gtaagaataa agatcagcaa tgtcctgcgc cagacaaaac ttggtttaaa gcgggctact
    47461 tcatggattc tctttaagat caaggtacaa gacacagcaa atccgatcat tgtcgccaat
    47521 aaagggccgt atacttcaaa taaacgaatg gctgggtatt gaagaaggag tttcactaga
    47581 aacccaataa ccaaataatt aattgccgcc ttgttttcaa acattccttg cagcatgttg
    47641 gaaactagca tatatagtcc taggaagagt cctacaaaac ttgcttggat cagtacatta
    47701 cttcctagag aatccggtgt ataaaataat gtatttagcg gataggcaag taacataaca
    47761 ccaaatgtcg ccggaaacat aaaaaatgaa aacaactgta aatttccgct tgtcaatttt
    47821 gccagaccta ctcgatcttt caacgtaaca gcttctgtaa tcaacggtaa cccagtagac
    47881 gcgatcgatg ttgccaatgc aataactacc atcgtcaact tatctggatt ggcactaaaa
    47941 atcgaaaaaa gatccagtaa ctgtgcattg gaatactcgg tggatgcaga catgatcttc
    48001 ataaaagtga actgatcgac taatttgaag atcgttaccc ctgaacccac aataataaac
    48061 ggaatcgctt ctttaacggt atctaacaac aattccttcg ttgcaatatt tattttgttt
    48121 tcgctgtagt gaataaacgc cgatgtatac gcttgatgtt tcttcaaaaa atacaaaagg
    48181 acaagaatac ttgctagcat accgataaat gccgcgaaag ttgattgcgt gaccgccgtc
    48241 acatagtcac catccatgac tttcatgatg atgaatgtag ccaatagcat ataaaaaata
    48301 cgtgccacct gttctacaat ctgcgacagc gcataaggca tcatttcttg attgccttgc
    48361 aaataccctc gtatcacact catacaagga aaaaccaata cagcgatact caaagaacgc
    48421 atcgttggaa tcagttcttc tccgccacca gaagcatgag ctagccaagg agaggcgatg
    48481 tacatgaaca aagcaaacaa caggcctaac ccgcccatca tctgtaatgc acggataaat
    48541 aatcgtcgtg aagtgccata ttcattcaat gaattatagc gtgcagtttg ttttgcaatc
    48601 gcagcaggta ttcctgctgt agagatcagt agaaacaatg catatatatt gtatcccata
    48661 ttgaataatc cattggcagc cttagcattt tcgcccatcc aagcatacca gggaatgata
    48721 tagacagcgc ctagcaatct tgaaatgata ttactggcgg tcatccaagc agagcctcgt
    48781 gccatttttt cttgcggtgt taattgatct aatgctggtt ttctttgatt atccatcggt
    48841 cagattccaa ctttctacaa aacattacta tcattttaat tggtaaaaca gaaactggca
    48901 atcgatttta tataactttt ataagaacaa ttgttttttt gaattcggtt tcgttttttt
    48961 ggtaaagtaa agaaatatac agccttttat ggctaacatt tataggagat atcaatgaca
    49021 caagaaataa aaaaactacc cgttatattt ttaggtcttt tctttatcac agttggattg
    49081 aattggttct tgctccctca cgatatagct tccgccggag tgggcgccat cggacattta
    49141 gttgaaacgg ccttttctat ccaacgctca gttactgttt ggagcatcaa tcttatgatg
    49201 ctgcttctag ccgctgtcct attaggaaaa tcagtatttt ttaagactgt agcgggaagt
    49261 ctgctttttc ctgttgtttt agagattgtt ccaaaagtgg aaatgatctc ctcacatttc
    49321 ttttcactga tttcaggaag tcttttgttc agtcttgggg tttacacatt gtacacagtc
    49381 ggggcctcaa atggcggtat aacgataccg ccgattattt tccacaaatt ttttcggctt
    49441 ccaatgccgc aaggactttt acttaccaat agtcttatcg tctttttgaa ttattatgtt
    49501 tttggattgt tggagacact attcgttctc ctatctatta cagtcagttc attgtttatg
    49561 aaaatactca tccgcttgtc ccctgtgtca agaaaatttg aataaagctg gattttgtca
    49621 tagcggaaac aaacgatata ttaaaaagag tgtgctataa taaaccaaga aattgaataa
    49681 agcgagggat caatcaatga gcttctcttt agaagacatc cgtcatttac tattaaaaga
    49741 aaatctatta aaagaatttg tttcaacaag aggctggcat cttgatgtac cagaaaaagc
    49801 tgaatttctt cagttaagtt atgattcaag aaaagctgat gcttctactt tgtttttctg
    49861 taaaggaatg aatttcaaag aagaatattt ggattcagca atcgaacagg gtattcaata
    49921 ttatgtatca gaacaaccat acgaaaattc agcagtagga atcatcgtaa cggatatccg
    49981 taaagcaatg gcgcttcttg ctatggcttt ttacgactat ccgcaaaata aattgaaagt
    50041 gatcggattc actggaacaa aaggtaaaac aactgctgcg tactttacaa aagcaatctt
    50101 ggatcacaca acaaataaaa aaacagcatt gctttctact atgaatacaa cgttagatgg
    50161 caaaacatat ttcaaatccc atttgacaac gcctgagtca ttagatttat atcgtatgat
    50221 gtcagaagca gttgaaaatg gtatgactca tctagtgatg gaagtttctt cacaagctta
    50281 caaaacacaa cgcgtatacg gcttgacttt agatgtcgga atcttcttga atatctcgcc
    50341 tgaccatatc agtccgatcg aacatccgac atttgatgac tatttctatt gcaagcgaca
    50401 attgatcttg aattcaaaaa cagttgtttt aaatcatgaa agtgactatt ttgatttact
    50461 tagggaaaca gccgatctat tccagattcc aacgatcact tatggtcgtt cggaagaaag
    50521 caattatcaa gtgatccgtt cagataaagg tactcacggt tttactttat cttctcatga
    50581 agatcgctta gctatctgcg atactgctta tgatattttg ctggctggag gattcaacca
    50641 agaaaatgca gccagtgcga tcattgccgc agcactaaca ggtgcctcca gtcaagatgc
    50701 acaagacgga ttaaaagaag ctcgtgtacc aggccgaatg gatcaattga tccaatccaa
    50761 tggagcgcat gtctatgtgg actatgcaca taattatcta agcttgaaaa cattgctgaa
    50821 atttgccaaa aatgaacatc cagatggccg tgtaattgtt gtattaggca gcccaggaaa
    50881 caaagcaatc tcccgtcgac atgattttgg aaaagtgcta tcagaaacag ctgacatcgc
    50941 ctttttgacg gcagatgacc cagcatttga agatccgaaa aaaatcgcgg aagaaatcaa
    51001 tgaagcaatt actaatccag atttgatcgt tcattatgaa atggatcgtc ctgaagcgat
    51061 tcgacgcgct ttagcagaaa gcgctccgca agattcagtc gttattgcgg gaaaaggcgt
    51121 ggatccctat caaaaaatca atggtgtaga tgaaccttat gaaggggatt atgcaatcgt
    51181 gaagcggttg attgaagaat aatggtattt atatactagt ggtttcccat ttctaagaaa
    51241 aaaagggact gtgatttttt gtcacagttc cttttttctt agaaatcatt ttaacttttc
    51301 actagctaat tctgctgcct tttctctttc ttcatttaat aatttattat catagaattt
    51361 gataaatggg aaccagataa tgaatgcgat gattgcacaa atgactgcta acacagcagc
    51421 tttccaatca ccaccactac caacaaatgc tccgatcccg actggtgaag gccacggcat
    51481 ctgtgcaagc atcggtttga cgatttccag ccgaatggca aaataagcga gtgtagcaga
    51541 agccatcgga gctaagaaaa acggaaccgc taaataggga ttgtagacga ttggcatccc
    51601 gaaaatgatt ggttcattga tattgaataa tcctggtaca agtgaggctt ttcctaacac
    51661 tttcagctga tcagatttcg cgaggaatgc aataaagatg atcaatccta aagtcgcacc
    51721 tgatccacca acggttacat aagaattgtt gaattctcct gccaacggat aatttgcgcc
    51781 ttgtgcgtta gctgccatat tagctaatac gatcggggtc aagaaagaag tgatgatatt
    51841 cgctccatgg atccctacga tccacaatgc atggatcaag aaataaatca ccatgacacc
    51901 aagccatgta ttcgtcaact gcgtaacaaa cccaaatggg atagcaatca ttttgaagat
    51961 atccgttcct agtgcaacta ataatccatt gatgatcatc accacaaacg caatgacaaa
    52021 tgttgggatc agagcagtga aagaacgaga aactcctggc ggaacaacat ctggcatttt
    52081 tatgacccaa tttctcttga cacacataca atacaattcg accgcaataa tcgacataat
    52141 aatagctgta aagattcctg aagttcctaa acgttcgaca aaagagccca tcctaatacc
    52201 atttactaca gtttctgtct cattgataga agcaatcaag ctgattttac catcagtcat
    52261 gatcaattca gggatacaca taaagaatgc aaaaacagat agtaatgccc ccgtgagcgg
    52321 attaacattt aatttttgtt catctcgttc aattgacgtt aattcataag caaacacaat
    52381 ggcaaagtaa atagataaaa tccccatcgt cattgtattg acgatcatgt acaagtcact
    52441 aactttgaaa aaagttgcat taaaaaatcc ttctaaaaat gggaacggta atggcaaaat
    52501 atttaaaacc aaaaacatcg agcctacaat cgtgaaagga atagaagcca tccccgctgc
    52561 catgacagcc cgaacgattt taagttgcgc aattttcccc ataggtccca tcaggtattt
    52621 ctgcaaaaaa tcaaacatta gttattctcc tttcctaaat ataacgcttt ttcatattgt
    52681 ttaatacgga tatactgttg gtcttggttg agtgaaattt tctttaaacg atactgtata
    52741 aatgcactgg caaaaatacc gcttacaaca agaatgaaaa caaataactg tcctccattg
    52801 ttatttgcca taaaaggata caagaatgta aatcctgagg taaacaacac tggaatcact
    52861 aataaattaa agacactctg gaacaaaaaa taccactttg tccatggaac gttcgtttgg
    52921 tgttttcgat aaagctttac ttgttctcct actgcaggca aaatagctaa aatcagaatc
    52981 atcggtaaac tacttcctaa acttttagct gatagaagca gaatcatcca ttgcatgttc
    53041 atgaaaaaga aaaaggcagt caggtaacgt acgattagat aacgattgaa atacatgttt
    53101 ttcaaactaa gttgcttttt ttctaattcg attttccttt ttactgtatc ctgcacaatg
    53161 atccttcctt tctatttatt tttttgatac aaataattca tttcctgtgc aacttccaat
    53221 aatgtcatcg tcgtcatcag atgatcttgt gcatggacca tgataatttc catttctatt
    53281 tttgtcccgc tggcatattc tttcagaagt tgagtttgtg actgatgcgc atgaagaatc
    53341 tcttcatttg cttgtcgcaa cttctcttct acttcttcaa acatctcttt acgcatcgag
    53401 cgaaatgctt catgtatcag tgtccgtgca tttccgctat ggaaaatgat atcaaaagaa
    53461 gtcacttgta gtgtttcact gtttattttt tcagccatct gttttcctcc ttattcgatc
    53521 agtttgataa atttactgct gaaattctca aaaataggtt cagctaagat ttcctgctgt
    53581 acttttagct ggtcaactaa cctaacgatt gctttagtca cgaccgtaat tccttcattt
    53641 tcgacataag aaggcgaaac taaaaaaaca aaatgaattt cttgatattg atcccactgc
    53701 atcccagaag gaatcaatgc aacggctacc tttgtttcga ttccaactgg aacagcggga
    53761 tgtgggactg ccactgtatc actgaatatg atttgtccca tattttcacg ttgctggatc
    53821 tgctttcgca tttctcttat atatccttct tcttcattta tgctcagctt ttgcagcaaa
    53881 tcatgaagaa tttcttcctt tttcggttcg tacgtataag tcttgaaaaa tttttcagac
    53941 aactgttcgg tgtaaatctg ctttttttgc tgtagagaaa atgctggtat cggtctatct
    54001 gaggaatgat agggtataga ttctccaact acctttcgta ttttacgaac atcatcttca
    54061 ttcaaaaaaa tactgacatg taaaactgga attttgaaaa acattgtcga aagatcaata
    54121 gaagaaataa tcaggtcgat tccttttaaa gttgtttcat tgatctcata atagcctttt
    54181 acacttacca ctgtaatatt tttaccgaat tcactgacta cgcgattctt taatagttgg
    54241 gcactgccgt aacccgttgc acagataatc aatgcatgta gtttatgcgc agctctttct
    54301 ttttccaatg ccgccatgag atgcaaagcc aaataggccc attcatcttc attgatggta
    54361 tagtttttca aagccggcat gttgctgaaa tgccttttta ctgcgtcaaa gactttggga
    54421 ttttctttct ttatctcctc agtcaatggg ttctcaatgc gaatacctcg gctcaatcga
    54481 atcatcatcg gtgacaaatg atcgagtagt ccattgaaaa gctggagatc ctctactaat
    54541 gaaaaatgaa attcctgaga caatcttttc agaactttcg ctaattcctt tgatagttcc
    54601 tgatcatttt gattttcttt gtgattcgac ttagccatga gatgtaatgt caaataagca
    54661 atttcttctt cgggaaacga tacacctgcg attacctcaa tacgttgaac gatccgctgc
    54721 gccacttgat actctactcg cttagaaact tcttgttcga tgcctaattc cttgatttca
    54781 aacccttctc ggagccgttt gatccccaaa gccaagtgta aagtcagatt ctgtatgata
    54841 aaatccgaaa cttttaactt agcttctctt gtttcatcga gaatgataat gactagctct
    54901 tcaaaactga tgtctgggaa aaaacggctt tgccctaaat attctttcaa tgaatttcca
    54961 taatggtttc caaaaaaagt atccatgata aaatgccgtc gatttctttc ttccccttcg
    55021 atccatgtcc cttgaccatg cttagaaacg atttttagtg aatatggaat caatcgctcc
    55081 ttgatttctt gcatgtcctt tgtcaaactg gaacgactga tataaagctc ttctgccaaa
    55141 tcatccataa aaagaatggc atcttccaaa agcaattggt tcaatatata cttttgtcga
    55201 tcttcggact cataaaatcc ttgcggttct ctagcatatc caggtactat ttcttgccga
    55261 ctcaaaaaca agtcaaatgt cagtctttgt aaaatatgca gttggtagcc ataacctggt
    55321 ttagcaatga tcttacctcc gtttttttct actaactctt tgatccgctg caagtaatta
    55381 cggattgtcc gatcagataa taacaattca gaagctaaac gttgactggt gacatactcc
    55441 ttcttgtgat caatcaaata tctcaacagc aatttttcct tctgtttcat tatcatccac
    55501 tcctattcca tcatatgttc tcttcgatca cctctgctaa cttctggatg cctgtaggga
    55561 ttgggacata cgcttggaaa gggatactaa caacaggctt tccaacagat tctcctaatt
    55621 ttttgaattt atccaaaaac atcgtcgttt gcgggctgat cagaaataaa tcaaaatcac
    55681 tattcttaat catattatcg ccttctgtag ctgaaactgc atctacgagt acctcttctc
    55741 ttttttgctt aaagaaatcc gttgtctttg aggccatcat cgaggatgac attcctgccg
    55801 cacaaataat caatgctttt ttcataaatc aatcactcct tttattttta taaaccaagc
    55861 atatcttgta agcgttttct attcaaaata tatatttccg tagcattgcg gaaaaaatgt
    55921 gtatcatatc ttgaataata atttctggca ccgtgatata ctagtgatag aattttttca
    55981 ggaggggatt tagtgagtat cacagtgaat attttgtata caagtacaaa tggacaagcc
    56041 agaaaatttg cagaagaaat ggtcgaaaga aacattgtca aagcgattcg tgcagaagaa
    56101 ggaaacgaga aatatgacta ttactttcca ctagaagatc cagaatctct tttactgatc
    56161 gaccgttgga aagatgaaga agcaatcgaa aagcatcaca aatccgaaat gatggctcaa
    56221 ataaacgaac tccgtaaaaa gtataaatta aaaatgaaag tcgaacgttt cactgattta
    56281 ccgtaaaaag atacacatgg aatgatagca atttatcatc catgtgtatc ttcacttttt
    56341 ccttattttt tattcgatct catctaatga ttcaaaccgt gtttttctct tatttttcgg
    56401 ataagtattt cagtcacccc aatatacatg attcctaaac ataccccaag gatattctca
    56461 aaaatgcgga tcgttactgc tcctggaacc ccgaataaac tggcagtgat tgccaaagca
    56521 ccaaaagaat taaaaactgt tttatatcta taggtagaac aaacacctaa agctagacca
    56581 cctaatatac cgacccagtt aaaaggaata aattggctga taccaataaa taaaacacat
    56641 ccaatcaatg agccaatgat tcggtctact gctcgttctt tgaaaccaat cgacatcaat
    56701 ccatagctag atacaataga agaaaatgca aaccctgccc acatcaatcg ctgaaaaggg
    56761 acatactctc ctgcaacgat caaaagacta atgccaaatg catagatgag catccaaatt
    56821 ttttcctgcg aatacatgcc tttcaaaaaa atctctttaa acaagctttt gtctttgttc
    56881 ttttctcgat gttttctgta aaggagaact gaaaaccaac aaaaaaacaa aaataataag
    56941 ctacttgttt gtgtaaagaa attcttgttc aacgaatctt taggtaacga ataaacaata
    57001 aagagatatg aaaagccgta caaagaagca ttccccattt tgggatcact agcggttgcc
    57061 attaatatgc tgcttagtaa aataaaatga atcaacatgc ccataactga ccatttgatc
    57121 agctggacat acggtgctac taatagtgag aacatgacga ttgctaaacc tatgatcgaa
    57181 tgggaaatct tataaccaaa gtcaacaaaa cgaatactca tcaacataca gaataaaacc
    57241 acagcgtatg gtttatgctt cgattcaaat aatgttgtaa ttataatgat aaaacaaatg
    57301 gcaaacaata cgatgaataa tgatcgtaaa aacaatgaac aaatatacat gcacttttct
    57361 tttttagaag ctgcttctcg tattttttgt tttaaaataa acggatctag ttgtagagac
    57421 tgataaaaat ccacctgttg tcgtcctttc tttttacttt tattttttac agtcatctat
    57481 gacaggttgt aaatactatg gaacatcata tggcgttgtc attttcttgt caactatttt
    57541 tcctattcat gtttttataa aaaaacatat cgttttcttg tatgattaaa tcaccacaaa
    57601 ataaacaact gagagaacga tatgctttat gaatggttct atcaaaaaaa ttctgagatc
    57661 aatagacaaa aatttgatga ttacagaggt ctcttacgaa accttacaga agaaaaaaac
    57721 attgatcgtt gctgcagttc tcttccctgc tccatgtgtc tgtagaaatt gtggttctgc
    57781 tgtggtagat ggaaatagga aattaatggt ggtgaaaaac aagaagaagg aaaccattgt
    57841 ccactttgaa taatataatc atatgccaat ggttatacgc ctaaaaaagc agcgctatac
    57901 ctgtaaaaac tgtcgaagcc attggaacgc tcaaagttat tttatccgtc caaggcactc
    57961 gatttcaaat catgtcagac ataaaatcac ttctttactg actgaaaaag tgtcgttatt
    58021 ttttatttcg aaaagttgtt aggtatcttt gacaaccgtt attcgcacat tgaaagagtt
    58081 gagaagctat ttaccaaagt cttccaaaag aattctgtct tgagtgttga gggttgtgaa
    58141 tttcgttctc acgtttccgt tgaggataaa ctgagtttta tttccgcgga tggcgagaca
    58201 gaaaaattaa tcgagaaaat ttacctacac aaaaaattcc tcgattaaca aactatttcc
    58261 ttagctgcac taatcctaaa gaaatagaat tcttagttac agacatgaac gccacctact
    58321 ttcagctcac caaacatgtt ctaccaaatg cgaaattggt gattgatcga ttacttggtt
    58381 tttccacgcc tttcaaggag gcgtaacctt tattcacgag ttggttgaag ctttccgaga
    58441 caaaagaccc gacttgtttt tctccttatt gacaaagagc cattaaaact agagaaaaaa
    58501 ttacaactga tcgctgatta tttgtagaaa gaaaatcaaa gtattaccca ataaacttga
    58561 gtcattaggc aaaaaacact gcgaaactca agaatgattt tcgcagtgtt tttgtatatt
    58621 ttttattaac tagtattact acaaaggttt atttttcact tctcaacgca gcacaaaatt
    58681 gtctttactt atttactggt tgggttcaac cttctctact ccgatactaa tatttgtttg
    58741 tatacccctt ctaaaatcgg tagtttccat tcaattgatg ggtactagtt gattttaaaa
    58801 actatgctta ttcaattttt tattttagct catatatttc gtttctttct aaattttata
    58861 ctgatgaaaa caagtagcac acccaatatt gacaatataa actggctaat gatggtttct
    58921 ccagtttttg gaagatgctt atttccactg cttgttggat tgtttcctct tatatctgag
    58981 ctatcagcaa cttttctatt ctcttttgtt aaaaagatcg ccacttcttg ttctttttcg
    59041 atcttgaaag ttactggtgt cgcatccaat tcataccccg ttggcgcttg agtttctacc
    59101 agctgatatg ctcctggtgc taagccatct atcgccagtt ttccatctgc tcctgtggtt
    59161 agacctgact gcagaacggt tccattggca tcttgtaact caaaaacagc tccttgcagg
    59221 acttctccgc tttggtcatc gatctttgtc aacacgacac cgcctggtgt aagtcgattt
    59281 tctttcgtca attctaccac cgctgtctga cttctttcga tctcaaactc gattggtgtc
    59341 gcatccaatt cataccccgt tggcgcttgg gtttctacca gctgatacac tcctggtgct
    59401 aagccgtcaa tcgccagttt tccatctgct cctgtggtta gacctgactg cagaacggtt
    59461 ccattggcat cttgtaactc aaaaacagct ccttgcagga cttccccgct ttggtcatcg
    59521 atctttgtca acacgacacc gcctggtgta agtcggtttg ctttcgtcaa ttctaccacc
    59581 gctgtctgac ttctttcgat ctcaaactcg atcggtgtcg catctaattc ataccccgtt
    59641 ggcgcttgag tttctaccag ctgatatg
//
LOCUS       DBBGSZ010000015        57869 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.015, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000015 DBBGSZ010000000
VERSION     DBBGSZ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 57869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57869
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.015"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            220..786
                     /gene="amaP"
                     /locus_tag="ACIZE5_001261"
     CDS             220..786
                     /gene="amaP"
                     /locus_tag="ACIZE5_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HGC6108417.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            799..987
                     /locus_tag="ACIZE5_001262"
     CDS             799..987
                     /locus_tag="ACIZE5_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HGC6108418.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1000..1557
                     /locus_tag="ACIZE5_001263"
     CDS             1000..1557
                     /locus_tag="ACIZE5_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGC6108419.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1589..1831
                     /locus_tag="ACIZE5_001264"
     CDS             1589..1831
                     /locus_tag="ACIZE5_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGC6108420.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            1859..2086
                     /locus_tag="ACIZE5_001265"
     CDS             1859..2086
                     /locus_tag="ACIZE5_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108421.1"
                     /translation="MKNKFENRSDTRCGSFLYILYEVFFIPYEKISLKIKKDENKRFS
                     IKRRPFIFCLYLCEKRKRAQHIKLLLIVCLL"
     gene            2172..3386
                     /locus_tag="ACIZE5_001266"
     CDS             2172..3386
                     /locus_tag="ACIZE5_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HGC6108422.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            3417..4844
                     /locus_tag="ACIZE5_001267"
     CDS             3417..4844
                     /locus_tag="ACIZE5_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HGC6108423.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            4867..5793
                     /gene="glsA"
                     /locus_tag="ACIZE5_001268"
     CDS             4867..5793
                     /gene="glsA"
                     /locus_tag="ACIZE5_001268"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HGC6108424.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            6001..7461
                     /locus_tag="ACIZE5_001269"
     CDS             6001..7461
                     /locus_tag="ACIZE5_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108425.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            7682..9445
                     /locus_tag="ACIZE5_001270"
     CDS             7682..9445
                     /locus_tag="ACIZE5_001270"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HGC6108426.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            9529..9987
                     /locus_tag="ACIZE5_001271"
     CDS             9529..9987
                     /locus_tag="ACIZE5_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HGC6108427.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            10096..10779
                     /locus_tag="ACIZE5_001272"
     CDS             10096..10779
                     /locus_tag="ACIZE5_001272"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGC6108428.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            10926..11540
                     /locus_tag="ACIZE5_001273"
     CDS             10926..11540
                     /locus_tag="ACIZE5_001273"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HGC6108429.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            11556..11762
                     /locus_tag="ACIZE5_001274"
     CDS             11556..11762
                     /locus_tag="ACIZE5_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108430.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     regulatory      11987..12153
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            12301..12858
                     /locus_tag="ACIZE5_001275"
                     /pseudo
     CDS             12301..12858
                     /locus_tag="ACIZE5_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            12916..14955
                     /locus_tag="ACIZE5_001276"
     CDS             12916..14955
                     /locus_tag="ACIZE5_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HGC6108431.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKIAFDSLGGKAASTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(15064..16215)
                     /locus_tag="ACIZE5_001277"
     CDS             complement(15064..16215)
                     /locus_tag="ACIZE5_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGC6108432.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(16369..16899)
                     /locus_tag="ACIZE5_001278"
     CDS             complement(16369..16899)
                     /locus_tag="ACIZE5_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HGC6108433.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(16998..17348)
                     /locus_tag="ACIZE5_001279"
     CDS             complement(16998..17348)
                     /locus_tag="ACIZE5_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HGC6108434.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(17505..19034)
                     /gene="ahpF"
                     /locus_tag="ACIZE5_001280"
     CDS             complement(17505..19034)
                     /gene="ahpF"
                     /locus_tag="ACIZE5_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008785 - alkyl hydroperoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000302 - response to reactive oxygen
                     species [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HGC6108435.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     RTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(19044..19607)
                     /gene="ahpC"
                     /locus_tag="ACIZE5_001281"
     CDS             complement(19044..19607)
                     /gene="ahpC"
                     /locus_tag="ACIZE5_001281"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HGC6108436.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(19751..20413)
                     /locus_tag="ACIZE5_001282"
     CDS             complement(19751..20413)
                     /locus_tag="ACIZE5_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6108437.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            20597..22243
                     /locus_tag="ACIZE5_001283"
     CDS             20597..22243
                     /locus_tag="ACIZE5_001283"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HGC6108438.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            22234..23316
                     /gene="uxuA"
                     /locus_tag="ACIZE5_001284"
     CDS             22234..23316
                     /gene="uxuA"
                     /locus_tag="ACIZE5_001284"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HGC6108439.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(23424..24977)
                     /locus_tag="ACIZE5_001285"
                     /pseudo
     CDS             complement(23424..24977)
                     /locus_tag="ACIZE5_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            25125..26266
                     /locus_tag="ACIZE5_001286"
                     /pseudo
     CDS             25125..26266
                     /locus_tag="ACIZE5_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(26392..27471)
                     /locus_tag="ACIZE5_001287"
     CDS             complement(26392..27471)
                     /locus_tag="ACIZE5_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGC6108440.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVIDFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(27580..28020)
                     /locus_tag="ACIZE5_001288"
     CDS             complement(27580..28020)
                     /locus_tag="ACIZE5_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGC6108441.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTSLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTPQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(28077..28487)
                     /locus_tag="ACIZE5_001289"
     CDS             complement(28077..28487)
                     /locus_tag="ACIZE5_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HGC6108442.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(28668..29102)
                     /locus_tag="ACIZE5_001290"
     CDS             complement(28668..29102)
                     /locus_tag="ACIZE5_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC6108443.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVSFEERKQLFEKYM"
     gene            complement(29202..30050)
                     /locus_tag="ACIZE5_001291"
     CDS             complement(29202..30050)
                     /locus_tag="ACIZE5_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGC6108444.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAVLGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLFFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFVFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            30439..32205
                     /locus_tag="ACIZE5_001292"
     CDS             30439..32205
                     /locus_tag="ACIZE5_001292"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HGC6108445.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETRRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVRDHLDYLTDLGVNGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVYDREDKLYFTRELEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            32307..33566
                     /locus_tag="ACIZE5_001293"
     CDS             32307..33566
                     /locus_tag="ACIZE5_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGC6108446.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            33713..35014
                     /locus_tag="ACIZE5_001294"
     CDS             33713..35014
                     /locus_tag="ACIZE5_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6108447.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            35017..35868
                     /locus_tag="ACIZE5_001295"
     CDS             35017..35868
                     /locus_tag="ACIZE5_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HGC6108448.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            35881..36696
                     /locus_tag="ACIZE5_001296"
     CDS             35881..36696
                     /locus_tag="ACIZE5_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HGC6108449.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            36847..38013
                     /locus_tag="ACIZE5_001297"
     CDS             36847..38013
                     /locus_tag="ACIZE5_001297"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC6108450.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            38243..38890
                     /locus_tag="ACIZE5_001298"
     CDS             38243..38890
                     /locus_tag="ACIZE5_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HGC6108451.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            38974..39918
                     /locus_tag="ACIZE5_001299"
     CDS             38974..39918
                     /locus_tag="ACIZE5_001299"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HGC6108452.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            40053..41504
                     /locus_tag="ACIZE5_001300"
     CDS             40053..41504
                     /locus_tag="ACIZE5_001300"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HGC6108453.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            41525..42361
                     /locus_tag="ACIZE5_001301"
     CDS             41525..42361
                     /locus_tag="ACIZE5_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGC6108454.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            42361..43020
                     /locus_tag="ACIZE5_001302"
     CDS             42361..43020
                     /locus_tag="ACIZE5_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGC6108455.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSIHQS
                     I"
     gene            43146..43835
                     /locus_tag="ACIZE5_001303"
     CDS             43146..43835
                     /locus_tag="ACIZE5_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108456.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            43841..44797
                     /locus_tag="ACIZE5_001304"
     CDS             43841..44797
                     /locus_tag="ACIZE5_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HGC6108457.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            44841..45353
                     /locus_tag="ACIZE5_001305"
     CDS             44841..45353
                     /locus_tag="ACIZE5_001305"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6108458.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(45609..46157)
                     /locus_tag="ACIZE5_001306"
     CDS             complement(45609..46157)
                     /locus_tag="ACIZE5_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HGC6108459.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(46246..47427)
                     /locus_tag="ACIZE5_001307"
     CDS             complement(46246..47427)
                     /locus_tag="ACIZE5_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside transporter C-terminal
                     domain-containing protein"
                     /protein_id="HGC6108460.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(47663..49171)
                     /locus_tag="ACIZE5_001308"
     CDS             complement(47663..49171)
                     /locus_tag="ACIZE5_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HGC6108461.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATCLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            49330..49521
                     /locus_tag="ACIZE5_001309"
     CDS             49330..49521
                     /locus_tag="ACIZE5_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108462.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            49724..50641
                     /locus_tag="ACIZE5_001310"
     CDS             49724..50641
                     /locus_tag="ACIZE5_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coiled-coil domain-containing protein"
                     /protein_id="HGC6108463.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            50634..51707
                     /locus_tag="ACIZE5_001311"
     CDS             50634..51707
                     /locus_tag="ACIZE5_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108464.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            51855..52373
                     /locus_tag="ACIZE5_001312"
     CDS             51855..52373
                     /locus_tag="ACIZE5_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108465.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            52354..52746
                     /locus_tag="ACIZE5_001313"
     CDS             52354..52746
                     /locus_tag="ACIZE5_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HGC6108466.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVVFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            52822..53757
                     /locus_tag="ACIZE5_001314"
     CDS             52822..53757
                     /locus_tag="ACIZE5_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HGC6108467.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            53890..54669
                     /locus_tag="ACIZE5_001315"
     CDS             53890..54669
                     /locus_tag="ACIZE5_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HGC6108468.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            54662..54979
                     /locus_tag="ACIZE5_001316"
     CDS             54662..54979
                     /locus_tag="ACIZE5_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HGC6108469.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            55223..56833
                     /locus_tag="ACIZE5_001317"
     CDS             55223..56833
                     /locus_tag="ACIZE5_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGC6108470.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            56990..57838
                     /locus_tag="ACIZE5_001318"
     CDS             56990..57838
                     /locus_tag="ACIZE5_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGC6108471.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT        19251 a        10225 c        11300 g        17093 t
ORIGIN      
        1 ttgaataata tcctttaagt atagccagca atcaaaagta aatagagaat aagtaagcaa
       61 ttgttatttc agtatcagac tggcaataaa acgccgttat gatccagcaa tgtttggtag
      121 cgctttattt actgatgcta tgctaactgt tcgctatcta tactgtgatt gtcggtagag
      181 ttatttacag ggtaaaaata agtttatagg aggtggaaaa tgaataaggg gttaaaaata
      241 atcggtgtta tcatgagttt actgctactt tcagtatttc tagcgattgc gttgatcaat
      301 gcgccgtata ttatgcctga acaattggaa cgatttcgct tctttacttt aacgaattac
      361 tacatgcaac aatatatttt ctgggcagct gtagtatttg ccgttcttgc tattatcatc
      421 ttgctagtcg ttcttttcta tccaaagtca agaggaactt tcgttatgaa acgggaagat
      481 ggcaaactaa caatcgacaa aaaagcgatc gaagggttgg tacgttccca tttacacgaa
      541 gaagagttca ttcattcacc taaagtacgg atacgttcaa cgaaaaatcg aatccatatc
      601 catgtcaacg gagacttgaa acgaacttct tcattagtag ggaaaacagg tgtattgatg
      661 caagatatcg aagaagaagt aactaaagta ctcggaacaa aagaaacggt caaagtggca
      721 gtcacataca gcggttatga agaacaagaa gatacaagag actacaagca ctctcgagtg
      781 gaataggagg gccaaataat gaaagaacta ttttcagcat acaagctccc tattatcttt
      841 gggggtcttg gactactgct agctgtttta tggttaacga ttggattttt caagacattg
      901 ttgatcataa tcatgacagc aattggcgca ggaatcggtt tttatttgaa acagtcagga
      961 atagttgatc aattttttaa atcataggag gaaacaaaga tggaaaacaa aaacatgaat
     1021 acaacaaatg gatcagtttt ggcaaatgaa aaaggagaaa accgcatgat gaatggtgaa
     1081 ttgacttatg aagacaaagt catccaaaaa atcatcggtt atgcattgaa agatgtagat
     1141 ggtctattga cattagatgg cggatttttc tcaaatatgg ctgaaaaatt agtcaacaca
     1201 gataacgtaa cagcaggtat caatacagaa gtaggtaaga aacaagtagc tgtggatcta
     1261 gatgtgatcg tagaatacgg taaagacatc gaagatattt acaaccaaat caaagaattg
     1321 atcagtactg aagtaaacaa tatgacacat ttagatgtta tcgaagtgaa tgtgaatgtt
     1381 gcagacatca aaacacaaga agaataccaa aaagatcaag aaacagtaca agacaaagta
     1441 acagaagcag caaaatccac aggacaattt gcttcacgcc aaacagataa agcaaaatct
     1501 gctgtaggca aaggtgcaca aaaagtcaaa gaaaataacg aaccacgtgt acaataagaa
     1561 gtaagaagtc agttaggagg aatttaaaat gggatttatt tgggcattaa tcgtcggcgg
     1621 tatcattgga gcaattgcag gagcaatcac gaataaagga tcatcaatgg ggatcatcgc
     1681 aaacatcatt gctggtttag taggttcagc aattggacaa gctttactag gaacttgggg
     1741 accaacaatt gcaggaatgg ctatcattcc atcattgatc ggtgcaatca ttttagtatt
     1801 agtcgtttca ttctttgcac gtaaattata agcaaattga agaaaaactt atgttgaaat
     1861 gaagaacaaa tttgagaacc gtagcgacac tcgctgcggt tcttttttat atattttata
     1921 tgaagtattc tttattcctt atgaaaaaat atctttaaaa ataaaaaaag acgaaaataa
     1981 acggttttct ataaaaagaa gaccgtttat tttttgtctt tatttgtgtg aaaaacgaaa
     2041 aagagcacaa cacatcaagc ttttattaat tgtctgtctt ttataaatgc aagtattaat
     2101 tcaaaaaaac agaagaaaaa aacaactaca ccttctttta tactcgtaat cgtagaaagg
     2161 aggcgaaaaa aatgaataca ttacctatca atacaggaga tacagcattc atgattttat
     2221 gtacagcaat ggtttgcctg atgactcctg gtctagcttt tttttacggc ggattagcac
     2281 ggaagaataa tatactaacg atcatgtctc aatcttttct ctccgttggg ataacaacga
     2341 ttatgtgggt atttggtgga ttcggattgg cctttggacg ggatatcggc ggtgttattg
     2401 gaaacccggc agatttcttt ttgatgagac atgttacaag cttccccaac atgtttcatg
     2461 gtgcaacgat tccattttta atgttctttc tttaccaact gatgtttatc gtgattaccg
     2521 ttcctttgat gacaggagct tttgcaggga gattgaattt aaaaggctat attatacttg
     2581 ttattttttg gaatctgctg atttatttcc ctgtttgcca ctggatatgg ggtggcggat
     2641 ttttggatca gatgggattt agagatttcg ctggtggagc agtcatccac acgacagctg
     2701 gattcggctc tttagcatgt atcctcacac ttggtcaaag aaagattcct ttaggagaaa
     2761 gaagtcagca tagcagtctt atggcagctg ctatcggtac aggactgctt tggtttggct
     2821 ggttcggttt taattccggt ggtgcacttc gagcagatga acaagcagtc aatgcatttg
     2881 gttcaacatt catcgctctt gcatttgcga tgattacttg gctgatcatt gcaaaagtaa
     2941 aaggaaatgg ctttgatttt gtcgacgtac taacaggatc cgttgctgga ttggcagcca
     3001 ttacgccttg tgccggttat gtagaagcaa aaagtgccat gctgattggg atcattgcgg
     3061 gtatcgtctg tcatgctgct gttgattttc gtaaaaagaa acaatgggat gatgcacttg
     3121 atgtgtgggg tgttcatggc atgggcggat tcacaggtac gattctgata gggatctttg
     3181 catctaacag ccatttacta acgaatccaa gcagctggta cttcttaggg attcaagtga
     3241 ttggtgtcat cattactgcc gtgtatgcct atgtgctgac aacagtgatt ttaaaatcgg
     3301 cgatgcactt tacaacgatc actactacaa aagaagaaca agaagaagga ttggactttt
     3361 tcttctttgg caacaaactc aattgaaaca aattcaaata gaaaagagga agattcatgc
     3421 aacaaagcaa aacgaaaatt cctgcaaaaa aattaacgtt ctttggcttt ttggctatga
     3481 ccatctcaat ggtcgtttca ttatatgaat atcccacatt cgcgacctca ggcttcagct
     3541 tagtattttt cttgttatta ggcggtttgc tatggtttat ccctgtggca ttgtgcgcag
     3601 cagagatggc aacggtgaaa ggatgggaaa aaggcggtgt ctatacttgg gtcagtcgca
     3661 cattgggaaa acgattcggt tttgccgcaa tctttttcca atggtttgag ataacagttg
     3721 gctacttgac catgctgtat ttcttaactg gtgcattatc ctatgcaacg ggtattggtg
     3781 ctatacaaaa caataaatat ctgaaattgg caatcctatt gattattttc tgggctattt
     3841 tactctcaca gttaaaagga accaaataca cttcattgat tgctcggatc ggttttgtag
     3901 ctggtatctt gttgccagca ttagtcttgt ttggcttagg gatccattat gtcgcttcag
     3961 gcgctccact acaaacgata ctgtctatga aaacattgat tcctgatttt tcgaaattgc
     4021 ctacgctggt tgtttttgtt tcctttattt tagcatatat gggcgtagaa acatctgcca
     4081 gtcatgcaaa tgaaatggaa aaccctaaaa aggattatcc attagcaatg tttgtattgg
     4141 ttattctggc aatcatttta gatacttttg gcggattgac cgtcgctact acagtacctc
     4201 aacatggttt gtctcttaat acaggggtga ttcaatcgtt agaattccta ttaagacaca
     4261 ttgatccaaa tcttgcatgg attgcgaaaa ttcttgcgat tcttgtttgt ttaggtgtca
     4321 tcggagaaat tgcttcttgg gtaacctctc cttcaaaagc acttcacgta gcagcagaag
     4381 aaggattact tcctgaatat tttgcaaaag aaaacacaca cggtgttcct gctcatttga
     4441 tgatcgcaaa tgggatcgtt gcaacaatct gggcagccgt ctttacatta agcggcgggg
     4501 ggaataatct ttcatttctt gcagcgatgt cattgactgt tgtaatctac ctgatgttgt
     4561 actttatgtt tttcgcgggc tatttgaagc tggtttttaa agatgacagt cttgaaagag
     4621 cctatcaggt tccaggcgga aaagttgtaa aagtaatcgt tgcttgttta ggtcttttga
     4681 cttcactttt tgctttttgt atctcatttg ttccacctgc tagtatcgca gctggacagc
     4741 atgggattta tgaaacgatt ctgattgttt cttatcttat cgtcttagtt attccattta
     4801 cgatctacgc atgccgtcat aaattccagc atgcagaaaa ataaaaaatg aaagctggtt
     4861 attcaaatgg aagtaaaaga attagaacaa ttgattggaa aaaatttcca ctattatcaa
     4921 acaggacaag tggcggatta cattccagca ttagctgaag tggatcccaa acaattaggt
     4981 atggcgattt atgatttgga tacaaaacaa ctgattgagg gaggagacgc cgatgtgcgc
     5041 tttgccatcg aaagcatgtc aaaagttccc gtattgttat tagcaatcaa agacaacgga
     5101 atagaaaaag tctttcaaac aatcaacacg gaaccaaccg gttttgcctt caattctatc
     5161 atgaatatgg aaatcaatca tcgcaaacat ccaatgaatc cttttgttaa tgcaggagcg
     5221 attgcaacaa cctcgttgat tgccggtaaa gatgcagatg aaaaatttga gcgaatcttg
     5281 tcatttatga aagagatctg tgatgatcct aatatcacat tgaatgaaga aatctatcat
     5341 tctgaatcaa gaacaggtga tatcaatcgc tctcttgctt actatatgaa aggtaatcaa
     5401 atgatcgaag gagacgtacc ggagatactc gatgcttatt tcagacaatg ctccctcaat
     5461 gtcaccgcta caggcatagc aaaattagct gctgtgctgg caaataaagg aattgctcct
     5521 tggaatggca aacaaatcat tactgaagaa agtgctacaa tcgtcaaatc aattatgaca
     5581 actgctggtt tgtatgatga atcaggagag ttttccgtcc atgttggtgt acctgcaaaa
     5641 agcggtgtag gcggcgggtt gatggcagct gtgccaaatc gttacggcat aggtgtcttc
     5701 agcccggcac tagatccatt tggtaacagc gcagctggta tccaattgtt gaaagatgta
     5761 gtcaaagaac tagacgctga catctttgaa taaccattct tgaaagaggc tggggtaaaa
     5821 gtccaaacgg ctcaaagcta cctacaatga ggctgaaatt gtgagcttgt ttgacttttg
     5881 tcccagtttc tttttttatt ggtttttgaa agggcttttc taaataaaaa ggaaacaaaa
     5941 atacgattta cagatatgat taaataaaat cataagaaaa actggaggcg tgtatcagga
     6001 atgctggaaa attacatcga gcgaaatata tttagaaaag tgtatctgtg tgaacaatta
     6061 tttgaattcc aagaaataga catcgaacaa acagctattt ctctaagggt gactacacca
     6121 acgatccttc acgatctaga aagtctagcc gagtgtctag aatattgtat aaaagaacaa
     6181 gtaagagaga agcataagta taaactcgta ttcaaacatg gtattgctct ttctgagctc
     6241 acacagtttc tgtacggtca atcttatttt ttaaagtttt taagttatta ttttaatggt
     6301 atattcacga gtacagaact ggctgatctt gaatttattt ctttgagcaa agtatataca
     6361 atcaaaaaaa tcgtattgga tttttttaaa gaaaatgatt atttgaaaaa taaagaaatc
     6421 attatcccag aatttgactc gcggaacatc ttgctagctt tagtacgtta tgtcaattgg
     6481 gaaggctatg aaaataaaaa tccgtatgta gaagaagctt gtaacgagtt gattgattat
     6541 gtagagactc atttttttaa aagaagatat tcggaagatg aaaagtcctt tatcatacga
     6601 ggaatagaga tcgcaatcgg aagaaaggca tttccccttg gactgaaaga agaagataag
     6661 aaaagcgcag aaacgaagcc gttatttcaa ttagtctgtc aaggattgga agagcaaaaa
     6721 ggaattctag acttacaaga agaagatgtc tattatattt tttctttgtt caacagtaga
     6781 aattatacca atgagaacat ggagctgtta agaaaagatt tcgaagttgt ttataaaaat
     6841 tttgttctca atgacctatc actgaatgaa ttgattttac agattattag tatcgctgaa
     6901 atcgacgatg cagaaaattt tattttcaag caatcctttt tacaatttgt ccgtacgttg
     6961 tgggcagatg gacaagtatt tttaccggaa aggatctatc ttctatcaga aaaagaacaa
     7021 cttctgtacg gaaaaattgt agaaatattg gaagagtgga aaaagaaaaa tcaaatccaa
     7081 ctaagatgga atgaaaattt cattcgaaaa ttcgtcaaaa gtctttcttt gatcaacagt
     7141 gaacaagcgg ggagacagga aatagaaatt tttgttgttt cagaaagttc agtcaaacaa
     7201 tttttttatc gaacccaatt tcatttgtat gcggaagaag gcatcgctga aataaatcct
     7261 attttatttc gttcattaga agaattgcct gatgaatgtc tatgtgcgaa aaaaagagtg
     7321 gttttgtgcg atgctgctag ctatcaaaat ggattagaaa ctgaaaagac aaagatctat
     7381 ccaatctcat taaaaggtgc aaacatccat ttgtatcata ttgctcagga acttcaccta
     7441 ttaaaaaaac atatttcttg atgagacctt aattaggaga ccttctacaa agctttttaa
     7501 ttgtctgtag aaggttttta tttgagtcct gattcgtgcg aagatctact tatataacaa
     7561 gctttctctg aaattttttt aaaatgctat tgacttagag tcaactctaa gtagtagaat
     7621 agataaagtg taacaaatct attttcatta aaagaagata gtacggagga gagaatgtat
     7681 tatgagtaca gtattacatg tattggatgc aatcaatagc cccgcagatg tcaaaaaatt
     7741 atctgttgag gaaatgaaac agttggcaga agagatgcgc caaaaaatct tgcaaaagga
     7801 cagcgatgta ggtgggcacg ttggtccgaa tctaggtgta gtagaattaa cgattgcgtt
     7861 tcattatgta tttgattcac caaaggataa aatcgtttgg gatgtttccc atcagtctta
     7921 tggtcataag cttttaactg gtcgaaaaaa tggttttgaa aaaggacatt accgtgaagt
     7981 gagcggatat tccaaccaac atgaaagtaa acatgactat tttacagtgg ggcacacatc
     8041 tacatctatc agcttagcaa caggtttagc taaagcgaga gatctgaaga aagaatcagg
     8101 aaatgtggta gcatttatcg gtgacggctc cctaagtggt ggcttagctt ttgaaggatt
     8161 gaacaatggt ggtgttttac aatccaatct aatcgtatta gtaaacgata atgagatgtc
     8221 tattgatgag aatcatggca gtttatataa aaacttagct gagcttcgtc aaaccaacgg
     8281 taaaagcagc aataacctat ttaaagcaat gggatttgat tatcgttacg tggataatgg
     8341 aaacgatctg gaaacggtga tccgtttatt tgaagaagta aaagatattg atcatccgat
     8401 tgtacttcac gtccatacgg aaaaaggtcg cggttatcag ccggcaatcg ataataaaat
     8461 gaaatatcat tggcatgtac catttgatct gtccaccggg gaggcaaagc aagtaacttc
     8521 tggagaaaca tttaatatga tcatcatgga ttatttggat aagaaaatgc aaacaagtac
     8581 agctcctatt gccgcagtca atgcagcgat accaggcgcc tttggactga aaacattcca
     8641 agaaaaacat ccagatcatt attttgacgt ggggatcgct gaacagcact ctatcacttt
     8701 cgcttctgct ttggcttctc agggagtacg tccagtcgtc ttccaatcaa gtactttctt
     8761 gcaacgggca tatgatcaat tatcacatga tttagcgatc aacgagaatc cagtgattat
     8821 tttagtcggt ggcggaacga tctcagctag tgaccgaaca caccaaggaa catttgacat
     8881 tccttactta tcaagtatcc cgaacatcaa atatcttgct ccagcaacaa aagaggatat
     8941 gatctctatg ctagattggg cgttcgaaca aacagcgcag cctgtagcaa tccgaattcc
     9001 tacacatggt gtagaacatg gtacagctat cgcaaatgat tatagtattc cagcctatca
     9061 aacagtaaat aatggaggaa aagtagcaat tttagcttta ggcggttttc ttgaattagg
     9121 aaaagaaaca gtaaaagctt ttagaaaaaa aggaatcgaa gcaacgttga tcaatccagg
     9181 aacgatcaca gaaaatgacg tagaaacatt agataaatta aaagaaacac acgaattagt
     9241 catcacatta gaagatggta gtttgtcagg aggatttggc gaaaatatca gtcgttatta
     9301 tggtgattct tcaatgaacg tattaaattt tggtgcagag aaagaattca cggatagcgt
     9361 tcctgtaggg cagctttatg aacgttatca tttaacacca aaacaaatcg ttgaagatag
     9421 tctgcgtgtc ttgaatattc aataattcat tatgctcacc atccagataa ttgtttatac
     9481 tagtatctgg atggtttttt cattataaaa agcaaagggg tggatgttat gtatcagcaa
     9541 gtagaagaat atgtcaaaaa gttccaagaa aaatatccta gttatcaatc agaaaaatta
     9601 ggtttctttt catttgggga tacagaaaaa atggcagacg agttgagcga actagttgta
     9661 aaaaagataa agactggtac atcaagtggt tacgatctgt ataaacaaga gaatgagcct
     9721 ttaccaaaag ttggtcaatt agacgtggtc ctgaatggaa aaaatgaacc agtttgtatc
     9781 atcaaaaata taaatgtgac catcttgcct tttagtgaag tcacgaaaga gcatgcttgg
     9841 aaagaaggag aaggggatcg gacattagct tattggcgga aagtccatgc tgagtttttt
     9901 aaacatgctt ataaagaagc gttgaacata gaatttacag aagagaagct ggtcgtatac
     9961 gaagaatttg aagtaatttt cttttagtaa gaaaggtctg ctgaaagaaa tagctcatta
    10021 ttgtctcctg aatagaaaag ggttacattt ttatatgaag ctgtattttt atataacatt
    10081 actggaggag atattgtgga tacactggaa caaatcaaag gcggagtcgt cgtttcttgt
    10141 caagctttgg aaaacgagcc gctacacagt tcttttatta tggggagaat ggctttggct
    10201 gcaaaagaag gcggagcagt tggtattcga gcaaatacga cagaagatat caatgaaatc
    10261 aagcgaatcg ttgatttacc ggtaataggg attatcaaaa gagattacga tgggtcagaa
    10321 gtgtttatta ctgcgacaga aaaagaagtg gaagaacttt tggagacgca agcagaaatc
    10381 attgcactgg atgcaacttc tcgtaaacgt ccgacagaaa aaacaactgc tgaacttgtc
    10441 caaatgattc acgaacacgg tcggttagct atggcagata tttcgacttt tgaggaagcg
    10501 cttcaagcgc aagaagatgg ttttgatctt ttgtctacga ctttagcagg ctatacagaa
    10561 tattcacgaa agacgcagac acctgatttt gatttattga atcaaatcat agaacaagtc
    10621 gatatcccag taattatgga aggacatact gactctcctg aacaagtaga gaaagcatat
    10681 gaattaggtg ctttttcagt cgtagttgga tctattatca cccgtccgca attgatcact
    10741 aaaagatatg tcgaagccgc aagtaaagca aataactaaa aaacacgcac ggcacagatt
    10801 cttgacaaaa aagaaaaatt gatagatagt ttaaagcaga ttctaagaag atgaaaaaag
    10861 cattactttt cattttgtct tcaagatctg ctttttaacg aattttatag aaagaaggcg
    10921 aaaccatgtt tgaacggagt ccttcagaat tgacagaacg tgaaaattac aagttgctga
    10981 ttggttcagt catccctaga ccagtagcag tagtaacgac taaatcagca aaagatatag
    11041 tgaatatcgc acccttcagt tacttcaata tcgtcagttc gaatcgaccc atcttatcct
    11101 tggcgatcca gagaaaacaa gatgcagtaa aagacacagc aaagaatatt cttgagacaa
    11161 gagaagctgt tatccatatc cttgatgagg acaacgtaga agaagtaaat aaaacagcag
    11221 ccaatctgcc taatgaggaa agcgaactgt acctgactga cttgacttta actgattcag
    11281 taatcatttc agtaccagca ttgacagaag caaaagttcg ttttgaaaca tccttatatg
    11341 aacatgtcga gatacggaat aaaaataaag taacagctga tttatttttg ctagaagtac
    11401 agaaatatca tttaaatgaa acagtctatg atgataagac aggaaggatc gatccaagaa
    11461 aattgaatgc tgtaagccgt ttggcaggaa atgattatgc agcaatagga gaaattttca
    11521 cgattgcacg tcccgaataa aaaggagcac tagttatgtt aaaaataagc tataaaccat
    11581 cgacagattc aaaagaaatg aaaaaagaat atgaaacagt gaatgatttt ctgcaagggc
    11641 agtacttaga agttccgcca ttgcaagacc attttgtcgt tactactgtt actttagatg
    11701 gtaaggaaat agaaatgcca gatcaaacga ttagcggatt gtttaattac tttaacaaat
    11761 aaatatttat tccgaaaagt gaaaaaacat ataaaaaaac acataaaact aaaaaattat
    11821 caaagaatcc tggtgcaact gaaagaattt gcaacgggat tctttcaact tatttgttat
    11881 ttttttctaa aaaatattaa agattgttaa atttcactat ttcatttcaa attccattgc
    11941 ctaatcatta ggaaaagtct atcatgaact cgtaaataga atatagtaat aaccttgtta
    12001 ggtgaggctc ctatacaaac ataggctgtt gcccagaaac gtcgaaagtc gccaatgggt
    12061 aaaacagaaa ctgttggatt aaggcttttt ccaatagcta agaatgtttt ctttacgttg
    12121 tatagtgcta aaactcggac gatgagatga tgctaggtca gaattcttgt tcgaaaaggt
    12181 ttctgacctt ttctttatat ttttgtgact gacttatttg atgagacaaa ctcgctcctc
    12241 acctgacaag tggattgctg tgtgaggagg agatgcggtg aaaaaagatc gattggtgga
    12301 ggtcgctcgg attcacttct ggttgcacaa tacaaccaga aaacacaaca agcaaaactg
    12361 atctctatca tgagagattc atatgtcgat attccaggtt acggaatgaa taagataaat
    12421 gcagcttact cttatggggg agttgattta ttaaatcaaa cattaaagga aaatttcaaa
    12481 tttgaagctc cctattatgc aagtatcaca tttcaagatt ttatcgattg cgttaatgaa
    12541 ctgtttcctg gtggagtcaa gatcgatgca gaaaaatctc tagatttaga tggcgtatat
    12601 ataaacaaag gagagcaagt gatggatggt aatactttac tccagtatgc tcgatttcgg
    12661 gaagacaaag aaggagactt cgggaggatc agaaggcagc agcaagtgat caaagctatc
    12721 tctcagcagc tgaaagacgt aacttcaata ttcaagctac ccaaagcggt tgggaaatta
    12781 cttggtagta tccaaacgaa ccttccagaa agtgtgcttc tggattgtgg tatggatttc
    12841 ctcaaagaca tatgttagaa taaacaggta taaatagtga aataaaggaa tgacaagcaa
    12901 gagaaggagg aaaaaatgaa aagaagtgac aagcacggca aaaatcgaac aggcgcttat
    12961 attgccggcg cagtgatctt aatagcagct gcgggtggcg gttattttta ctaccagcac
    13021 tatcaagaaa cccaagcagt agaagctgga gaaaagacag ttgagcaatt tgtccaagct
    13081 ttgaacaagg gagattataa caaagctgca gaaatgacat caaaaaaggc ggcaaataaa
    13141 agtgcattat ctgaaaaaga gatcttagat aaataccaga atatatacgg tgctgctgat
    13201 gtcaaaggac ttcagatatc gaatctaaaa gtagataaaa aagacgattc tacttacagt
    13261 ttttcatata aagcaaagat gaatacctca ttaggtgaat tgaaagatct ttcttataaa
    13321 ggaacattag acagaaatga tggtcaaacc acgatcaact ggcaacccaa cttggttttt
    13381 ccagaaatgg aaggaaatga caaagtaagc ctgaccacac aagaagcagc aagagggaat
    13441 attatagatc gaaatggtga accattagca acaacaggca aactaaaaca attaggagtc
    13501 gttccaagta aacttggaga tggaggcgaa aaaacagcca atatcaaagc gattgcttcc
    13561 tccttcgact taacagaaga tgctatcaat caggcgattt cacaaagctg ggtacaaccc
    13621 gattactttg tcccattgaa aatcattgat ggagcaacgc cagaacttcc agctggagct
    13681 accattcaag aagtagacgg cagatattat cctttgggtg aagcagctgc tcagctgatt
    13741 ggttacgtgg gagatatcac agcagaagat attgataaga atccagaatt aagcagtaat
    13801 ggaaaaatcg gtcgctcagg tttggagatg gcttttgata aggatcttcg tgggacaaca
    13861 ggtgggaaat taagcattac agatgcagac ggtgtagaga aaaaagttct gatcgaacat
    13921 gaagttcaaa atggcaaaga tatcaaattg acaatcgatg cgaaggcaca aaaaatagct
    13981 tttgacagtc taggaggaaa agctgcatca actgttgcga caacgccaaa aaccggtgat
    14041 cttcttgcgc ttgctagctc tccaagctat gatccaaaca aaatgacaaa cgggatctca
    14101 caagaagatt acaaagctta tgaagaaaat cctgaacatc cattcatcag ccgatttgcg
    14161 acaggttatg ctcctggatc tacgtttaaa atgattacag cagcaatcgg tctcgacaac
    14221 ggcactatcg atccaaatga agtgttgacg atcaacgggc ttaaatggca aaaagacagt
    14281 tcttggggat cttttaaaac aacgcgtgtc agtagtgatg tatcacaagt agacttaaaa
    14341 actgctttga tctattccga taatatatat gcggcacaag aaacgttgaa aatgggtgag
    14401 aaaaaatttc gtacaggctt agataaattc atttttggtg aagaccttga tttgccaatt
    14461 agtatgaatc cagcacaaat ttctaatgaa gatagcttta actcagatat cttgctagct
    14521 gatactggat atggacaggg cgaacttcta attactccta tccagcaagc agcaatgtat
    14581 tctgttttta ccaacaatgg cacacttgtc tatcctaaat tgattgcaga taaagagaca
    14641 aaagataaga agaatgtcat cagcgaaaca gcagtacaaa cgatcgtgcc agatctgaga
    14701 gaagttgtgc aagatgtaaa tggtacagca cattctcttt ctgctttagg gattccgttg
    14761 gcagcgaaaa ctggtacagc ggaaatcaaa gaaaaacagg atgtaaaggg gcaagagaac
    14821 agtttcttgt ttgctttcaa tcttgataac caaggttata tgatggtcag catgttggaa
    14881 aataaagaag atgatgattc agcaaccaaa cgagcatcgg aactattgca atacctcaac
    14941 caaaattatc aataaaaaat tgctttttaa gtacagtaaa aggactgtgg cgttatcgtc
    15001 acagtccttt tttcaaataa acggttttca cgatgtctct ttcacaactt ctttttgatt
    15061 tactcacact tcataaactt tttttgtaaa atatttgaga acaagtggag aaataagtgt
    15121 acttaataaa atcacgataa ctaaaggtga atagtactgt ggttcgatca attgactttg
    15181 ctgtccaatt tgtaaaatga tcaaagccat ttctccacgc gaaatcatac cagcaccgac
    15241 catcaatgaa ctatgttgag aaaaaccggc aatctgagca ccaaaataac ctccaagcaa
    15301 tttggtcaaa atcgctacaa gcgtcaatat agaaataaag agtagttgtt cactaaagtc
    15361 agaaaaatca acttctaatc ctacactgac aaaaaatact ggtataaata ctgcatatcc
    15421 taaagcctct acattgtggt atacttcttc tttaaccttt gtctgactga cagctatccc
    15481 agcaaaaaaa gcaccaatga cagagctaag cccaacaaga tccgctacgt aagacattcc
    15541 taaacaaata actagcgata cgatgataat agaagaattt gcgtacactt tttctgcaaa
    15601 tgaaagtagg aaaggcgcaa tccatttgac taataagaaa ataaaaacaa aataaattag
    15661 ctgttcaatc aaaacaagcg gtaaagaagc attgctagaa gcttcccccg ttagaaaaga
    15721 taggctgaaa cttagaacta aaacgactaa aatgtcatct accacagaag cacccaaaat
    15781 tgttgatcct tcttttgtat tcactacgtt tagttctttt aatacttcta ctgaaatact
    15841 gacagaagtt gccgcaagaa taatcccaaa gaaaatcgct tcatttcccg aaacttggaa
    15901 tgctttgcct gtcaaccagc caaaaacaac cgggaagatg atcccaagca aagcaacgaa
    15961 cataccaggt cggaaatatt ttttcaaaag agataaatca ctttccagac cagctaaaaa
    16021 cattaataag atcacaccaa tctccgaaaa gtcatggact agaatatcag gtttgaccca
    16081 attcaatcca gcttggccta gcaaaacacc aacaagtaat tgtccaatca ctgctgggat
    16141 acctaatctc cgcgagatat gtgagccaat cgttgttgaa atcaatatca ggcataaaat
    16201 accaataaat tccattctca tcattccttt gtataaaata tagcccgaac ttagcataac
    16261 atacattatt gaaaaaatag gaaaatatac tcacaaaaaa accaacaatc caaaagattt
    16321 ttttggattg ttggttttta tacggtctat tttaataact aaaaatgatt aacgtatagt
    16381 catttttctt attctgatga aattgataat ctcctggatg cccatgaaaa tcaaaataaa
    16441 gccgaatatt tggaatagaa gcatcaaact tttgaatgga ttgaacaata agacgaatcc
    16501 gccaatcaac aacagaatac tactataaac actccaactt ttagcttttg tattcatgct
    16561 gaagaacaac tggaacaagc tgttgatgat aacagctaat ccaagaagaa tcggcaggat
    16621 agaaacgatt gcaggtgcaa aagcatagac gatcagagct aagatcagga aaaaaagacc
    16681 actgaacaga ccgatactcc aagaacctgt tttcctttta aaacggtaag cctcaaaaag
    16741 attcaacaac ccaagcaaaa caagataggc ggtgatcaga taaccgataa aatgaaaaac
    16801 agcagaaggg tttagcacaa tcgcaatccc agaaataata taaacagcag ctcttaataa
    16861 ggcgtatttt tgaatatttt gtttaatcgt ctcaaacata taagaaaacc tcctttgact
    16921 tattttaacg tgaactagtc attttaccaa attaaatgtt acaaaatgag cgaaggagaa
    16981 gaatatctct ggaaaaatca acttctgagg atcttttcca tttttttgcc ttttgctagc
    17041 tcatcgatca ttttatctaa ataacgaatt tctttcatca agttatcctc gatgtcttct
    17101 actcgtacac cacaaacaac acctgtaatc aaggaacgtg aaggattggg gacaggggct
    17161 tccgcaaaaa attgttcgaa agtcacttgt ttttgtagtt gatattctag ttctgtttgg
    17221 gaataacccg tcagccaaca aatgatttca tctacttcct cttttatacg atcttttctc
    17281 tccgcttttg ctacatacat aggataaacg cttgcaaaac ttgtcgtaaa aatacgattt
    17341 tgcgccataa tcagtcacct ttcttttttt caaattattt actacttata gtatataaga
    17401 aaaagagaag aaaaagcgat tattcaaaaa aacaaaaagg attgtgacaa aattcttgtc
    17461 accatccttt tttccgctct ctgacttttt acaatcttca tagctcaagt gcgcatcaga
    17521 taatcgaatg ctcctaaagc tgcagtagct cctgaaccca ttgaaacaat gatttgtttg
    17581 tatggactat ctgtacaatc accagctgcg aaaacgccgg ggatattcgt tgcgccattt
    17641 ttctcggtca ctatttcatt tcttggattc atttcgatcg ttctatctag ccaatccgta
    17701 ttagggagta agccgactag aatgaatact cctgaaacag ctagtgtatg catctccatc
    17761 gtacggcgat cgatatagga gagagattct acctgattcg taccgctgat ttctttcgtc
    17821 gctgcatgtt tgataacagt gacattcgca agagagacta gtttatcctg taagatttga
    17881 tctgctttta attctggtaa gaattctaga acatatacat gttttgctaa cccagccaaa
    17941 tcgattgctg cttcaacacc agaattacca ccaccgataa cagcaatctc ttttccttta
    18001 aataaagggc cgtcacagtg tgggcaataa gcaattcctt tatttttaaa ctctttttcg
    18061 cctggtacat tgatagaacg ccagtgcgca cctgtcgcga tgatggcggt ttttgcttta
    18121 agtgatatac cgttagctaa gccaatatta ataaaatgtt gctctttatt taaggaaacg
    18181 gcctgttgat tcatcataat gtcgataggg taactacgca catgactttc tacttgctgc
    18241 atcaattttg gaccttctgt gtaagaggta ccaatcatat tttcaatccc tagtgtttca
    18301 acgacttgtc cgccgaaaga atcagcgaca agtcctgtac ggattccttt acgtgctgca
    18361 tagatagctg cactactagc tgctggtcca ccgccaatca ctaatacatc ataaggttct
    18421 ttttcaaaca actcttcttc aatcaaaggg ccagtgattt tttcaacaat ttgttcgatc
    18481 gtcatgcgtc cgctactaaa ttcttctcca tttaaaaaca cagttggcac tgccatgatt
    18541 tttttatcat cgatttcttt ttggaacatc ccaccttcaa tcatcgtatg agtaatattt
    18601 ggatttaata cagctaatat attcaatgcc tgtacaacgt cggggcaatt atgacaagtc
    18661 aagctaacat aactgtcaaa atgcaatgtt tgtgttattt ttttgatttt aagactcaaa
    18721 gattcactga ttttcggtgc ccgtccacta atttgtaaca tagccagtaa aaaagaggaa
    18781 aattcatgac cgagggggat accagcaaaa acgattccac tttctttgcc aactggattg
    18841 atagaaaaac taggtgtgcg catcgaatct cttttttccc aagagatttt aggagacatt
    18901 tctgctattt ccttcgtaaa ttcagctagt ttttgactat tttcactatt atccaaacta
    18961 acagaaaaaa caataggaga ttcaatcagt gctaaatatt gttcgagatt ttgtttagtt
    19021 tctttgtcta acatatccac cacctaaatc tttccaacaa gatcaaaact tggtttcaat
    19081 gtttcgccac tttctttcca ttttgccgga caaacttcac ctgggtgggt acgtacatat
    19141 tgagcagcgc gaatcttatc aatcagtgca ctagcgtcac gaccgattcc atctgcattg
    19201 atttccatag cttgaacgat tccgtctgga tcaataataa atgttcctcg ctgagctaat
    19261 ccttgctctt catccaaaac atcaaaaata cgagaaatct gatgagacgg atcaccgatc
    19321 atcacgtatt cgattttacc gatagcatct gatgtatcat gccatgcttt gtgagtaaag
    19381 tgggtatcgg tagagcaaga aaagacttca acacctaaag atttcaatgt actgtattgt
    19441 tcttgtaagt cttctaattc agtaggacaa acaaaagtaa aatcagctgg atagaagcaa
    19501 agaatactcc agttccccat aagatctttt tcactgactt ctaaaaattc tccttgatga
    19561 taagcatgtg cattaaattc ttcgattttt ttcccaatca atgacatagt aaaacctcca
    19621 ataataatta tttatttata attattgtaa tttagttgga gttgcaaagt caatggatat
    19681 tttgttattt aataaagatt actcaaaaac gaaggttaat tataaaaata gaagaggtcg
    19741 caagaaaatg ctactgctgg aaatactcgg gataacgttg agtaacagtt tcctgttctt
    19801 tcagcatcat gtgtaagtgc aatcccgttt gaaatcgagc ttcttctggt tttttatcaa
    19861 ctaaagcctt gagtaaatca taatgttgtt ccatgatcgt ttcccatgga agcccctgaa
    19921 tggtcactcg taaccagcgg aaacgttcta aatgggtatt atggtcatct aaccagttcc
    19981 aaacttcttt tcttcctgca atttcgaaac aagcttcatg aaataaatta tctgcacgga
    20041 aaaaagcgcg ttcgtcattt attttgactg ctttttcttg ttcttctaaa atcgtttcta
    20101 gcactattcg tgtttgtgtg tccaatttgg aacaacattc aatcatgatt tgctcttcca
    20161 actgttctcg gacaaagcga gcattttctg cagaaacaag attaattttg gaaacatacg
    20221 taccactttg aggtatcgta tacacgagtt cttgctgacg tagttgaatc aatgcttcgc
    20281 gaatgggagt ccggccgata gcaagatgtt cctccagtgc cttttcagat attttccttc
    20341 caggttctaa gtcagcatag ataatttgtt tacgaatcgc ttgataagct tgtgattgca
    20401 agctgctttt catctttatt cctccaaaat catttctatg aacgtagtat aacagaagag
    20461 gtctgaaaaa caatctggta tgtcacatta actagtaaat ttgtataaat agtaaaattt
    20521 tggttgacat agcgattttt attgcataaa attcacttga atacaaaaac taatatgtta
    20581 gtttaggagg ggaaaaatga ttgatttaaa caactggagg aactttatcc ctgaattatc
    20641 tcaaaaagaa gtagaaatac ctcattttga ccgtgcatca ttaagagaaa atggacaaaa
    20701 aaatcctgtc tggatccatt tcggtggcgg aaatctttat cgaggatttc atgcagaaat
    20761 cgctcaacgt ttagcggatc taggcgaatt gtccactggt gtcattgttt gtgaaacatt
    20821 cgatgaagaa ataattgaaa gggcttacca agattttgat gatttgattc ttgaagtggt
    20881 catgccaagc agtggagagt tcgtcaaacg tatattagct gcgacagctg acagtctgta
    20941 ttgtcatcca gattgttctg aacactttga taagatgatt cgacactttg aaaatcctag
    21001 tttacaatta gttacttttg ctattactga aaaaggttat cgattgaaag atacaaataa
    21061 taaatatata ggaccgattg cagtcgatat aaaaaatggt ccaaagaagc catcacatac
    21121 aatgagtatt cttgctgtgc tactttataa acgtttttta tctggagctt ggccgattgc
    21181 acttgtctct acagataatt tttcacaaaa cggtagtcaa ttacgtactt ctttgctaac
    21241 gatcgcaaaa gaatggcaaa aggaaggtta tgtacaaaat acatttatcc aatacttatc
    21301 gaatgaagaa attgttgcgt ttccatggac gatgattgat cgtatcaccc cgaatccttc
    21361 cttgtcagtt agcaaaatgt tggcaaaaga gggcttttca aatatgtcga ttttccaaac
    21421 cgcaaaagga aataatattg ctccatttgt caatacagag gacatccatt atttaatcat
    21481 ggaagatcat tttcccaatg gacgtccgaa attcgaaaaa gctggggtat tcttgactga
    21541 tcgtgcaacg gtagataaag cagatacgat gaaggtgacg acttgcctta atcctttgca
    21601 tacgtcttta gctattatgg gttgtttact ggggtatagg agcatagctg aggagatgaa
    21661 agatccagat ttatcgctgc tagtttctga aatcgggtac aatgaaggcc tcccagttgt
    21721 ggagtctcca ggtatcattg atccaaagat ctttctggaa gaagtaatta ctgtgcgctt
    21781 ttctaatcca aatattccta atatgcctca gcgaatcgcc acggatacct ctcaaaaggt
    21841 ggcgattcgt tatggtgaga cgattaaaaa atatatggaa atagaagtta aagacccgca
    21901 gacacttgta ttcataccat tgactctcgc tgcttggctt cgatacctta ttggcattga
    21961 tgatcaagga aaaccattca tcccgagtcc agacccacta ttgacagacc ttcagcataa
    22021 gctttccgat attcaactgg gtacgcaaga tacatcacat attcatgaga aaatggctcc
    22081 tattttgtca aataaagaaa tttttggtgt agatctttac caagcagagc ttggcagaaa
    22141 aatagaagaa atgttcatca agatggtagc aggaccaaat gccgtacgaa aaacattaca
    22201 ggattactta caagaacatg gaggaaattt atcatggaaa tgacttttag atggtacgga
    22261 tcacaggaag aaaagattac cttagatgaa atcagacaga ttcctgcggt caaagggatt
    22321 gtaggcacat tgatggatat accagtagga gaggtatggc ctagggagag gatcaaagaa
    22381 ctaaaagaag aaattgagtc tcgtgggtta acactaaaag taattgaaag cgtcaatgtg
    22441 catgatgcca ttaaaattgg attaccttcc cgtgagcagt atatcgaaaa ctataagcag
    22501 acaatccgaa acttggcaga atatggaata gaagtcatct gctataattt tatgcctgta
    22561 tttgactggg tgaaatctga ccttgactac cgcttagaag acggctcatc cacgttagct
    22621 tttatatctg atgatattcc agatgatcca agagaaatcg tcgcgcgcat cgaacattcc
    22681 agcaatgaat ttggattgcc gggatgggaa cctgagcgct tagctcctat caaatccttg
    22741 cttgaagcct atgcatcagt agacgaagaa aaacttcgag aaaattttgc ctattttctc
    22801 caatcaatca tcccaacatg tgaagaggta ggggtcaaaa tggctgtaca tccagatgat
    22861 ccgccatact cgatttttgg attagctcga atcgtaaaga atcgagaaga tttagattgg
    22921 ttgtgtcgca tagtagacag cccttataac ggaatcactc tttgtacagg gagtattgca
    22981 gaagatccag aaaatgatgt atatgggatt ttagcagaat tttgccaaag agatcgaatc
    23041 ccatttgcac atgttcgaaa tattaaattt ttagctaatc gagatttcta tgaggcacca
    23101 cataaatccg aatacggttc attagacatg taccgcatac taaaaacaat gtatgacaac
    23161 ggatttaacg gatacatccg tcctgatcat ggaagaatga tctggaatga gacaggaaga
    23221 ccaggatacg gcttatatga tcgagcatta ggtgctgttt atctaaatgg attatgggaa
    23281 gcaatcgaaa aaggaaacaa aagtaaagat aattagtgaa aaaaactgta attttattat
    23341 gtaaataaga aggatgttca aattcttgat acataaatcc ggaggttgtt aataagcatt
    23401 cggatttatg tatcttattt ggtctaggaa gtaacttgat tttctttttt cgattgatcc
    23461 atgagtgctt cttcttttaa ttcaaagata tattctgaga tcctcataat cacttttttc
    23521 cagtcttctg gtgtgatgat tccttttaaa atatagattt ttttgatatg agaaggcaat
    23581 tgtttcaaag ggcagtcgct gataacgatg ttgcagttct ccataaaatc attttgtatt
    23641 ttgatcgatt catttgaaaa aatttgttct atcttaacga tcagatcttt actgatataa
    23701 aaatcacgcg tatagttcac accaatcaca attcgcggct gttttttgta gcgatcatac
    23761 aaatgtacta ggtcttcaac catccattgc acattttcct tttctaaaat aactggtaac
    23821 aagtgttgat tttgttctct gaaatccata taaaattgtt caatggcggt ttggacttct
    23881 ttcaatacgc tatgttcttg ataaagcatg aaagtaggaa ggggcgtatt tggttgattg
    23941 aagttaagaa atccattata aagtttattt cgtgcgaatg ccaatgagta aagaatcttt
    24001 tctttttcag gtataaacaa atcaaataca gtacaaaggg actccaccat ttctcttgaa
    24061 taaagaacat gaggaacgtt tgcttttttt aaaagtttgt attgctccaa gcttgtttct
    24121 tccgattcga ttttcgtgat agaaagtcga gctaaaatat tcactaagat gcgttgttcg
    24181 cgacaaattg gcagattagg tcgcaaaata tctacagaga gatcaataaa aaagtcaata
    24241 tattcatact ctgtgaattc tttttgtacg tctttcacag aagttgcagg aaaattctct
    24301 ttacatattt ttaatagaaa atataattta tctatcatac cgctatttag tcggtcaagt
    24361 acttcttttt taaaaaaagt attcatcata aaagccacta cttgcggatc ttcatcataa
    24421 aattctgtag cagtacttga aaagatgttc caataaatat ctaatgctgc atattgaatt
    24481 tgtacctctt ttccagaaaa agactttctg ccattattag aaaaggagat agacaaaccg
    24541 tactatgcta aaaatgcatt aatctttttc attttcgtat acaaataaga ggcactatag
    24601 tttgtttgct gactgaaact gataatcgaa tttgtctgac agctgaacaa agaagtcaag
    24661 atctgataac tgactgattc gttgcagtat cttccaaata gacgataata gcagtaagcc
    24721 ggatcaattc cttcaaaatt caactttaaa aaaggttttt gcttatcaat atgcagttct
    24781 gttagattga gacgctcaaa gtcttgttct aattctttga tgtatagtaa aaaatttgat
    24841 tcagacatat ggaaatgatc tgctaaatat tgtgtagtaa taaagaaacg atgttcagat
    24901 aggaaaagaa aaatatctaa ttttgtattg ctttttttct tcaagataaa cgttttaatc
    24961 gcttcttgag tttgcatgaa agaggctcct ttttacttaa attgttaaaa cttgaaaata
    25021 ttactgtttt tttcataaat ttagacaaaa aaacagtaaa catataggta gaatctctac
    25081 tatcttattt cttgcataca aaaaaatcaa ggagtgagag agttatgaga tattcaacca
    25141 tcttaatatc aacatttgca gccttaagct tatcgcttac tataaatcag acagtccaca
    25201 cagaggagac agaaacagcc aaatggacag aaaccaagtg ggccaacgtc aatcgaatta
    25261 cctttcagga tgaattttca tccttcaatt caggagtcgc aaaattaaga aaaggacaaa
    25321 cagcgaccat caaagcaaaa attgactatt cgggagactt agcacctata ctacaatcag
    25381 ctgttacatt tgagaatgtt gatcccactt tgtcgattgg ctatgacgag aacactttga
    25441 ctatccaaca caagcaagcg atatttacct tcaccgttac attaaatcag gacttgttaa
    25501 aaccagcgct ttttactgtc aaggtatcag atggactacc gaacgatcat catttaacgc
    25561 cgtatagtca gcggcagaca attgagcaag attcagccat cgactcagga ggagatcttg
    25621 ttgaagaacc aacagataaa ccagaaaatg aaaataagcc agaagtaccg cctacagaaa
    25681 atccagacgg agaacagaaa ccggaaatag aacctggaga agaacccgat acagaaactc
    25741 aaccagagcc agacaataaa tcaaaacctg aaataacccc tggagaaaaa ccagatgtaa
    25801 ctccagaacc agatacggat tctggaaacc aaacagtacc ggaaacaaat ccagacacag
    25861 ataatgaaac tgaaaatcca gaaaaaccag aggtagatcc agaagaaaaa ccagatgtga
    25921 ctccagaacc agatacggac gcaagagacc aaggaatacc agaaaaaata aacaaaaaaa
    25981 caattcaaga ggatggaaaa aaagagagta aaaaatcaaa tctagcaatt ctaaaaataa
    26041 atgaagagca gctgaataaa aaatcacgaa tatttgatag cgcccaatca gctgaaacct
    26101 taaaaagtag caaggataca acctttgctg tcctgaaacg aaaaataaac agctaccaaa
    26161 atccggagag tcacaaaaca aagttatact gtggagcgga atcattctat taagtatagc
    26221 aacaatgctt tctgcaaaaa gatttaaaca aaacagatct ctctaacatt tgaataatgt
    26281 ctgtgaacgc atttttcaaa taaaaagaaa tatccagaaa atgaccccaa aataccagat
    26341 tgaaatctga tatttggggt cgttcatact ttatctttct tcatatttat tttaagggat
    26401 atctgtttct tttggaagat ggttcgggat ctttttcact ttcaatacat ctaaaaagaa
    26461 ggtaaagatc ggaatgccga caatcaagcc ccaaacgcca aagaaccgtt cgctaacaag
    26521 taagaccaca aatgtataaa aaatcggcag ttctgttttg ctggacatca acttcggatt
    26581 cagcacataa gactcaatta gatggacaat caaaatcgta atcaggatat aaacaacatc
    26641 tcggatgcct ccttgggaat aagctatgaa agatagagga atacaagaaa tgataacacc
    26701 tgctactggg atcagactta aaatgaaaat catgatcgct aaactcagca gctgatgaaa
    26761 gccaaataca gccaaggcga ttgtagtgag caacgtattt aaaagagcga caacaaattg
    26821 agcttctaat accaaaccaa atgtattgac aaacttatcg gcaaaatagt aaatatcttg
    26881 aaagaaccaa gaaaattcac tttttaaaaa caatcttgag aatacaattg tttttttctt
    26941 ttcaatcata aaaaagaaac ttaagatgaa tgacatagca aacgccactg ccatttttcc
    27001 tatatcctgt aaatagccaa gcgcaatcga agcgccattt tgaagctgtt caaaaaaatc
    27061 gtttcgctca atataagtat ggatatattg taaaacagga tctgcatctt ttggctgatg
    27121 ctcgtaaaaa tcaataacgg actggatcat atcaaatgtt tgatgaataa gcatcgggat
    27181 atactttgtg aatgccagat agataaggta aacgatcagt gtataaatca tgatagctaa
    27241 aacacctgta gggattcgga caaatcgctg aatgatttga acaagatgaa tcatcaaata
    27301 agtaaagata aatgtgagca aaatggttgt aatcatactt ctaactaaga aaagaacaaa
    27361 aacgacaaat aataaaacag tgagacggcg tattttttca ttcgccaaaa aacgctgata
    27421 aacggtcaaa tcgacaacct ccaaataaca aaaaataaac acgttattca ttatatgatg
    27481 gaatatgaaa ataagaaaga gaaagagcaa aaagaaaaac cgctaaatga cgttatctta
    27541 tgagttggtt ttcctcataa aatcgttcat ctagcagttt cagccctttt tctggtcttg
    27601 atgaaaatta tctagcattt ttcgggtcag atgttgcagt gtatccaatt cttcctgttc
    27661 aagtggaaga taagacttga tcttttgtgg aataccttct gcttgttttt gcaacgcagc
    27721 accttgagga gtcagcgtaa catttacgat tctttcatca cccgtttcac gctgacgatt
    27781 aatataattt ttttctgcta acttttttag taagggagtc agcgtaccag aatccagaca
    27841 caaatcattt cctagctctt tcactgaagt ctttttcttt tcccataaaa ctaacatcac
    27901 aagatactgg gtataggtaa gattcagcgg cttgaggagg gaagtgtagt gtctaatgat
    27961 ttccttagag gcggcatata aaggaaaaca tacttgatta actaaatata gatcttccat
    28021 ttttccacct ccgctgtttt actatagtgt atcatagcgg atttacacaa aaaagtctat
    28081 tcactaactg ctttcagagt aacttctata tttccagctg tagcttttga atacggacac
    28141 actttatgcg ctgcctctaa taattcttgc gtttcttcca gagaaagacc ttcgatagat
    28201 ccttcaatct ctacacctaa gacaaagctc gtttcacttt ctgaataaag ggaaacttgt
    28261 gcactgacag tagaagcccc agagatattt ttttgctgtt tgatcaattc taatgcactg
    28321 ttaaaacatg cactgaaacc agctgcaaac aattgttcag ggttggttgc attttcgacg
    28381 cgtttaccag gagctgcaat attcaattcg aatgtacgat cgggattatg aacttctcca
    28441 gagcgtccgc ctgtgttgat cattttcgta gaatacattt ttttcataaa attaccacct
    28501 ttaattatat tttatacaat tgaattttac acaatataat tgtggaaagc aaagaaatgg
    28561 attggcataa gataaataag agaaagcaca tgaaacagac gcgctttctc gaatagcaaa
    28621 catatacaaa aaaatatcag agacaaaaac taatctcatc ataaacatta catatatttc
    28681 tcaaaaagtt gttttctttc ttcaaaactt acttcacgat ggacctgatg aagcatccat
    28741 aaataaccaa aaggatctct gaacattgag ttagtcacac caaagtccat catttctgtc
    28801 atttcttgaa tctctacaca gccatttcgt aatgctttat tatgtgtgtc ctcgatatca
    28861 gagacgatga tattgaacca gatcgtattt ggatgttcag cagtaggagc agtcaaacca
    28921 agagacgtgt tttcatccag catatggaat ctcgtgccat acaaggtaaa aatgacttca
    28981 ttattgcctc tagggtaatc tgttgcctca atcagttgta tttcatcaaa gattgtttga
    29041 tacagttcta gtgctttcaa actatcattt aatacaaaat ctatttccgt tcctttatgc
    29101 ataaagatct cctctccttt tcagtcgaac agttactaga ttcttttatt ataccagtta
    29161 aagaaaacgc attcaaaaaa atagcggatt tacttaccaa ctcattcgat tggatgataa
    29221 gtaaatccgc gtcccattac ttctgctacg ctgctgacaa tgacaaaggc acttggatcg
    29281 atttcttcta tcaatggttt cattcgggaa aattcatgat cagtcacaac gatcaataaa
    29341 acctcttttg actttcgatt atacccgcct tttgcctcta gcagggtaag gccacgtcca
    29401 atctcagcac ttaagcgaag gcggatgtct tccaaataat gttcactcat gaccataaca
    29461 gatttctttc gattgatacc tgtttcgata taagtcatga caattgaagt gattgcaata
    29521 gataaaatag cataaagaaa ctcttctatt ccaaaaacaa acagattaag agaaacaacg
    29581 aatgcgtctg taaaaaataa gccaatcgaa gtattcaagt ggaaatattt tttaaaaatg
    29641 aggggaggga tcgtcgtacc gccgctagaa gagttgtttt tatataaaat cgcaactcct
    29701 aaagcaaaaa tcgcacttcc aaaaatgaca gacaacaacc gatctgaagt aatcattgtt
    29761 tctggaacta ttgcaatgat taaaggaaaa aacaagcttc cgaaaagtac tttaaaaaag
    29821 ggttttttac ctaaaaatag aagagctagt accaacataa cgatattcaa cactaaaata
    29881 actatagctc ggtcaaatcc taaaacagct tccagtaata ttcctagacc gctgacacct
    29941 ccagcagcaa tatgatgagg ccctaaaaac atattgatag cgactcctaa tatgaagagg
    30001 gcaaaaataa tcttaatgta tgtccatata aattgtctcg tttctttcat ttatccactt
    30061 ccttaattca ttaataatac tcttatctta ttataactta cttttcacct taagttaact
    30121 ttaattaata aaaaaattag gctagtctaa attattatgt ttcattcttc tagaatatac
    30181 ttctacgtta aaaactgtta aaaaactttt actttagaaa attggagaaa ttgatcgctt
    30241 aagataaatt caggacacta aatagtacag gaagtagatt aaaactttta aaagttttaa
    30301 gtctatctat ttggcaagtt taaaaaataa aaattcggta tcaaaaaact gttaccgata
    30361 acatttttga aagcgttgtc ttttgtttct ctatcactta tagtgatgac gtcatattaa
    30421 aacacaagga ggaaatcaat ggatacagct gcaatttatc atcgaccgga aagtgaatat
    30481 gcatttctat atacgaatac aagatttcgt attcggcttc gtactaggaa aaatgatatc
    30541 aaaaaagtat atgtgctttg tggagatcca tataccataa caactgaaaa atggtatcaa
    30601 aaacaacgac caatgaaaaa atgtctaagt accaatgttc atgattattg ggaaattgaa
    30661 gtgacgagcg aaacaaggcg cttacagtat gcgttccatg ttgttgggga agataacacg
    30721 gactgttttt acggtgatca aggaattttt ccttatcgag aaaatgtgat tactgaacca
    30781 aatttttatt ttcgaatacc ttattttcat caaatcgatc gattcactat tccagaatgg
    30841 gtaaaagaaa cagtatggta tcaaattttt cccgaaagat ttgcaaacgg ggacaaagca
    30901 aatgaccccg aacacacttt accttgggga agtaaagatc cagaccgaga agacttcttc
    30961 gggggagatt tgcaaggtgt gagggatcat ttggattact tgacggacct tggcgtcaat
    31021 ggcatctatt tttgtcccat atttaaagcc acatccaatc ataaatacga tacgattgat
    31081 tattatgagg tggatcccgc ttttggcgat aaaaaacttt taaaaaactt gattgatgaa
    31141 gcacataaaa gagggatacg tatcatgttc gatgctgtat tcaatcatat gggtgtccat
    31201 tcaccacagt ggcaagacgt tctcaaaaac ggagaaaaat cgatctataa agactggttc
    31261 cacatccgtt ttttcccagt agattcttat cagatgactg acttaccaga aactgctgaa
    31321 aatatcccat atgatacttt tgcttttact ccattcatgc cgaaactaaa tacagcaaat
    31381 ccagaagtgc aaaaatattt gctggatatc gcaacttatt ggataaaaga attcgatatt
    31441 gatggatggc gtcttgatgt tgctaatgaa gtcgatcatc atttttggaa aaaattcaga
    31501 gaagcagtta cagaaatcaa accagacatc tatatccttg gagagatttg gcattcctct
    31561 caagcttggc tgcaagggga tgaattccat gcagtgatga attatgcatt cacagattcg
    31621 attaaagatt attttgcaaa aaagaaaatc acagcttcac aaatggtcag tggaatgaat
    31681 catcagcaaa tgctttacag agatcaggtg aacgaaggaa cattcaactt attagattct
    31741 catgatactg ccaggatctt gaccctttgc caaggtaaca aagaattgat gaagtctgtg
    31801 atggccttta tgtttcttca aaaagggtct ccttgtatct attacgggac agaaataggg
    31861 atgactggtg aagatgaccc ggattgccgc aaatgtatga tatgggagaa ggaggaacaa
    31921 gatctagagc tattcggttt tataaaagaa cttgtttctc taaggaaaca gttgtctaag
    31981 attatttctg aaggttctac tcagtggcta atagtatatg atcgtgaaga taagctctat
    32041 ttcacacggg aactagaggg acagatcatc tatgtttact ttaatcagtc aaaagaacct
    32101 tgggtagtag aacaggaaaa tgaggtgatt cttagtcaaa attgtcagtt gttagaagac
    32161 gggaaagcag agatacgaca atacggattt ttgatcatgt gttgaaaact gttaccggta
    32221 acaacaagaa agcgtttgca aatgaagatt tgtgcccatt ataataaggg tgtaacagca
    32281 cgttgaatac acaggaggaa atgaagatga aaaaaagaag tgtgaaacag ttgggtttag
    32341 ggttaatctc tttaggaatc ttaggcggat tagcggcttg tggcaatggt aactcttcag
    32401 cagaagggga agccgatgaa ggaaaaacgt taacagtttc cgttgattct ggatataaag
    32461 attatataaa cgaaataaaa aacactttcg aaaaagaaaa cgatgtgaaa atcaagctag
    32521 tagaaaagga catgttcgat cagttggaat cattagcgtt agatgggcct gctggaaagg
    32581 gacctgacgt tatgatggca gcatatgacc ggatcggtgc gttaggacag caaggacatc
    32641 tggcggaagt aaaactggga aatgaagcag cttacgatga aacagacaaa gcccaagtga
    32701 cttatgatgg aaaaatctac ggagaacctg cagtaatcga gacccttgtt ttgtactata
    32761 acaaagattt agtcgataca gcaccatcaa cgtttaaaga tttggagaat ctatccaaag
    32821 acagtcgttt tgcttttgag tcagaagcag gaaaaaatac aggattttta gctaaatgga
    32881 ctgactttta ttattcctat ggtttaattg caggttacgg tggctatgta tttggtgatg
    32941 atggcacaaa tccttcagat atcggtttga ataatgcagg tgctgtagaa ggaatctctt
    33001 atgcaacaga ttggttcaaa aatgtttggc caaagggaat gcaagacata aaaagtgcag
    33061 gagacttcgc cagccagcaa ttcatgtcca ataaaactgc agcaatcatt gacggtccat
    33121 ggcaagcgca aacatacaaa gaaaacaata tcaattatgg tgtagccaaa attcctactc
    33181 taaataatgg acagccttat caaccgtttg gcggaggaaa aggatgggta gtcagcaatt
    33241 atgctaaaaa caaagacctc tctcaaaaat ggcttgatta tgtaacgaat caggaaaatc
    33301 aagaaaaatt ctttgaaatg gtaaatgaaa tccctgcaaa ccaacaagct agggaaacag
    33361 caaaggctaa aaacgatgaa ttaacaacag ctgtgattga acaatatgaa acagctcaag
    33421 cgatgccaaa catcccagaa atgggcgaag tttggacagg tgcagaaaac ttgatgttcg
    33481 atgcagcatc aggttcaaaa acaccaaaag aatccgcaga tgaagcagta aaaacaatca
    33541 gtgaagccat agaacaaaaa tactgattaa aatgataacc gtccattttt ataaaaaatg
    33601 gaacaggtgc ttcagataaa agtggcaaga gcgagatgga aaattatctt gctcttgttg
    33661 ccattatctt aaaagcagtt tgcggtttag caagtttaga gggggcattc agatgcagca
    33721 agataaaaca agcaatatca acgaaaaaaa aatcacgctt tgttcactta ttccagggat
    33781 ggggcagttt gtaaatggcc aagcttttaa aggtatcgtt tttttcgcca tattcgtcct
    33841 attcattggt cagatgcttc tgggcggatt tcatgcattg gtaggattgg ttactttggg
    33901 aagtatacca atggaagatc attcattatt tattttgatt gaaggcactt tgcaattcat
    33961 cattacaatc attttcttga ttttttacgg tttgaatctt ttagacgctt atcgagtagc
    34021 gaagatgcgt caagagggca aaaaaatcaa tcggacgatg aaggaagtca tacataatat
    34081 aggtgatgaa ggttttcctt atctattgac acttcccgct tatcttctca tgatttttac
    34141 gatcattttc ccagtcctag ttacattgtt cactgcattt actaattatg acttcaatca
    34201 tattccacca gccagtttaa ttgattgggt aggggctaaa aactttttta gtatcttctt
    34261 tttaagctca tatcgtaata ctttttttgc agtcttttcg tggaccgtga tttggacttt
    34321 atgtgcaaca actttgcaaa tcacccttgg tattctcaca gcggttgttg ctcaccagaa
    34381 atttattaaa ttcaaacgta ttttcggtat cattttctta ttaccatggg cggtcccagc
    34441 ttttattact atcatgagtt tttcgaatat attcaacgat agcgtaggtg ccatcaatac
    34501 tcaagtgatt cctttcataa accagcttcc ttttgtagat atcagtgcaa tctcttggaa
    34561 aacggacccg aactggacga aagtagcaat tatcttagtg cagggctggt taggatttcc
    34621 ctatatctat gtgatggtta caggaatctt acaatcgatt tcagaagact tatatgaagc
    34681 agcaaaaatc gacggagcaa atgcatggca gcgcttttca aacatcacgc ttcctgctgt
    34741 cttcctagtg gcagcgccaa catttattac acagtatacg gggaatttca ataatttctc
    34801 catgatctat ctgtttaaca atggtggtcc cggaagcgta ggcggaggag ctggttctac
    34861 tgatattctt atttcctgga tctataaact tacgactgga acttctccgc agtattctat
    34921 ggcttcagca atcacgttga ttatctccgt catcgttatc tgtgtgtcat tgctggtatt
    34981 taaaaagaca aatgcgttca atatggggga ttaacaatga aaaaatttca ttcgagtgct
    35041 cgattccaaa aacgactttc tcactttttt acttactttt ttcttttaat actgtcagtc
    35101 attatcatct atccgctttt gatcacagca agtactgcct tcaagtcagg aaatattgca
    35161 gcttttagtt tagatctttc aagtgactgg actttaggaa actttactcg gctattcagt
    35221 gaaacacttt acgggacttg gtataaaaat acattgatca tttctgtcct aacaatgatc
    35281 gtacaagtga ctgtagtaac tttggcgggc tatacttata gtcgctatcg ttttatcggc
    35341 cgcaaatcaa gtttgatgtt ctttttagtg attcagatgg taccgactat ggcagcattg
    35401 actgcctttt atgtcatggc tttcttatta gaagcgctcg ataagtactg gttcttgaca
    35461 atgatctata taggcggtgg aattccaatg aatacttggc tgatgaaagg atactttgac
    35521 actgtaccaa tagatttaga tgaatctgct aaacttgatg gggcagggca tttcaggatt
    35581 tttttccaga ttgtattacc gcttgtcaaa ccgatgctcg ccgttcaagc attatgggct
    35641 tttatgggac cttttgggga tttcatgtta gctaagttcc tgcttcgaac acctgaaaat
    35701 cagactgttg ctgtcggctt acaaacattt atttctgatg tgacaaacca aagagtctct
    35761 ctttttgctg ctggggcaat tttgattgca ctaccgattt gtctattatt cttcttttta
    35821 caaaagaact ttgttaccgg cctgacatct ggcggaacaa aaggatagga gcagagtatc
    35881 atgcaaacat ttccgttaaa ctatttttcc gcattacgta cgccaactca agtgtttgcg
    35941 ggacgcaaac tattatcatg gcctaaattt ttcttgatat ttgtattttt agtttccttg
    36001 atggtcatgc ctgtgactct tttttatgcc aatcagatcc aagcgattcc attagaacaa
    36061 tttctatccg ttcattcgct gatcgatgaa caaggaaccc aaaaattttc tgaacttgaa
    36121 ttatctgaaa ctgggttaca agcatcgcaa caaacgatag ctgtgacccc tgaaattttg
    36181 gtaggtgtgt ctttatctga gaaacaacaa tccgatcatg gaacttttat tgattttgag
    36241 aaggaacaat gggtgatcca acaaaaggat aaatctggta tacgccgcta tacgatgaat
    36301 tatagcccat ctttccaacc agattctgta cgtacgcccg aagatttcca acgattttta
    36361 gaaagagaat tttatgccag taatcgtcca acaatcattt tatcttatag tttaagtctt
    36421 ggtcttgtcc tatttgtcat gacgagtctc attttattcg gggcttcctt tttcttgtgg
    36481 atgacaagaa aaagccaact ttcatccatt catacattca aagagagtgc aaatttgatg
    36541 ctgaatgtta tgggaatagg ttccatggca gcagcagttg tagggtttat ccactttgac
    36601 tttatcttga tgctaagtgt ccaaacaacg ataactgtct tgctgctttt atgggttttt
    36661 gtcaaaacaa gattcaaaga taagcgtgtc gaatgacaag tttaagcgat ttatgcgaca
    36721 atgaatgtga aaaaaatgaa aaataaagta gtttttgaaa aatttctgaa aaaattaaac
    36781 ttcttagttg attcttttct tttttagtat taacgtaata gggtagtttt tttaaggagg
    36841 aaaatcatgt tagagaaaac tttatacaat caattatttt cacgttcttt ctcgctccct
    36901 gtcgaagtaa attattggga cggtacaacg aaacaatacg gagatacgga cactcctccc
    36961 caaatcaaaa tcaatatcca tgaagaaatc ccaatgaaag agattacaag taacgcttct
    37021 ttggcactag gagaagccta tatggatcat cgaatcgaga tcgagggaag tatccaagca
    37081 ttgatcaacg atgcttatca gcaagcaaac agctttttac gaggaaaaga ttatctaaaa
    37141 tggctgccaa agaaagaaaa acatacgaaa caaaaaaaca aagaagatat ccatgcgcat
    37201 tatgacttag gtaacgactt ttataaactt tggctagatc caactttgac ttattcttgt
    37261 gcttatttca atacacctga agatacgttg gaacaagcac aaatcaataa agtccatcat
    37321 atcttagaca aactctttat caaagaaggc gaaacgttgc ttgatatcgg ttgtggctgg
    37381 ggaacattga tgttcactgc taccaaagag tataatgtca aggcaactgg gatcacacta
    37441 agtgaagaac aatacgattt gattaccaaa agaataaaag aagaacattt agaagataaa
    37501 tgccgtgtat tattaatgga ttaccgcgaa ctaaaaggcg aaacgtttga tcatatcaca
    37561 agtgtaggta tgttcgaaca tgtaggttct gaaaatcttg aaggttattt caaagtggta
    37621 aaagatttat tgaaaccaaa aggaacagct ttgatccatg gaatcagccg acaacaaggc
    37681 ggtgcgacaa atgcttggat caataaatat attttccctg gcggttatgt ccctggtgtt
    37741 actgaattag ttgataatat tacaaaaaac gatttgcaac tgattgattt ggaaagctta
    37801 cgtcgtgact accaattgac attagaacat tggacaaaga attttcatca agtccaagat
    37861 caagtcacga aagaaatggg tgattccttc tatcgaatgt gggatctata tttacaagct
    37921 tgtgcagctt catttgaatc aagtaatatc gatgtgattc aatatttgct tgttcaacct
    37981 ggaaacaatg acatcccaat gcatcgtgca taattgaggc aaaagtactg tttaaagact
    38041 atttaaaaag aagctaagtt ttatgatgct ccagaagtga acttttttgt ctaacttcta
    38101 ggattgtctc taaagcttag tttctttttc tttatatttt cataataaaa gtttggttct
    38161 ttaattttta aacatgacag aaaatttttt cttcgttata cttgtaatag aatactattt
    38221 tataacaaag gggatcgaat caatgaaaaa aactgttatt tatactagtt tatttgcagc
    38281 tttgttttta gctgcttgtc aatcaaatac caatcaaggc acatctggga atacgtcttc
    38341 cagtagcgaa cagcgctctt cacaggtatc ggactcctca acaaaagcaa gcacatcttc
    38401 gtctagccag acaaaaagtt ctagtgaagc aagtactcag tcagatatca aagtgtctgc
    38461 agctcgtgcg atcgaattgt tccaagataa atacccagat actgcaatta ctagtttgga
    38521 attagatagt gattggggat cttacttcta caagatagaa ggtgtcgatg atcaaaaaga
    38581 atacgaagca agaattgatg ctcaaaatga aaaaatggag acagagaatc cagaaactct
    38641 agatcgagat gaacaaaatg gtcaaaagaa aaaagaagat ggtctggatg ttgataaatt
    38701 gatcacgatt gaggaagcag caaaaatcgc cgtcgacaaa gtaggaagcg gtacggcaac
    38761 agattgggat ttggataaag atttaggtac tacttattgg gaagtcaaag taaaagacgg
    38821 caatcaaagt acatcagtca agatcaatag ccaaacaggc gaagtactgt caactgaaca
    38881 agatgattaa gaatttcttc ggaaaacaag agttgatttt tcttttagtc atgatacact
    38941 agacaaaata acttgtttga aggagcgatt tacttgagtt tagaaacgac ctttgccaat
    39001 catatctttg ccaatccttt gatgaatgca tctggtgtcc actgcatgac tacccaggaa
    39061 ttagatgaac tggctcattc agaagcagga gcatttatca ctaagagctg tacgatcaat
    39121 gaacgaaaag gaaatcccga accacgctat tttgatgttc ctttagggag tatcaattct
    39181 atgggacttc caaacttagg tttttcttat tatctagagt atgctcttgc gtatgaaaaa
    39241 gtgcaggaaa accaaaatca accgttattt ttttccattg ccgggatgag tgtccaggaa
    39301 aacttggaaa tgcttgagaa aatagaaaaa agtgggttta atgggatcac tgaattaaat
    39361 ttatcttgtc ccaatgtgcc tggaaaacca caactagctt acgattttga ggccacttat
    39421 gaaacactga aagaagtatt cagcatcttt tctaagccgc taggaatcaa attgcctcct
    39481 tattttgatt ttgctcattt tgatcagatg gctgatatct tgaatcagtt tccattgacc
    39541 tatgtcaatg ctatcaacag tgtgggcaat ggtttgtata tcgatacaga acaagaagca
    39601 gtagtcatca aaccaaaaga agggttcggc ggcattggcg gagagtatat caagccgact
    39661 gctttggcga atgttcgcgc tttttataca cgtttgaaac cagaaatcca aatcattggt
    39721 acaggtggga ttcggacagg acaagatgca tttgaacatc tgctatgtgg cgcaagcatg
    39781 ttacagattg gtacagagct tcataaagaa gggccggaaa ttttttctag aatcataaaa
    39841 gaattaacgc agattatgtc agaaaaagga tatacgtcaa ttgacgaatt taaaggcaaa
    39901 ttacgcacca tttcatagca aagagacgaa ggtcatgatt gatcttcgtc tttttttata
    39961 aaaaacactc gtctgttcat tcctgtgcaa gcgtactcat tgtatgttag acgaacttgt
    40021 gggaaaataa cagaggcaaa aaggaggata atatgaatga tgcaacagaa ttagcaaaag
    40081 agcttaaaga aaaagaattt agttttcaag aactagttac ggatatacag aaaaaaataa
    40141 agaagcaaaa tcatgaattg aatgcgtttg tcgcgcttga accattcgag agtaattccc
    40201 acgagctatt gattccccag tcagaaaaag ggccattggc tggtatccca tttcctttaa
    40261 aaatgctcgg tcaagaaaaa aagggatggc tagctacttc aggatctcgt ttatttgaaa
    40321 cacaccgagc ttctcataca tctaattatg tgcggcaagc agaagcgata ggtctagttc
    40381 cttttggaca aaccaatgcg ccagagtttg gtttcaaaaa tattacagac ccagtcatct
    40441 atggcccagc aagaaaccct tggaaccttg aatgtacacc gggcggatca agtggaggag
    40501 ctgctgctgc agtttcatca ggaatcgttc ctttagctgg tgctagtgat ggcggtggtt
    40561 ctattagaat acccgcttcg ttttgcggat tgattgggct gaaaccttcg cgagggacga
    40621 tgccagttgg tccatatgct tggagaggat ggcaaggagc tgctattgat ttcggcttga
    40681 cagtttctat gagagacacg gaggctttat tttatgggat gagaagtatc cattccggtg
    40741 cgccatatca agtatcgcca gttgagtggc aaacacatcc aagaaaaaaa cggttgaaga
    40801 tagctttttg tgttgattca ccgatccact cacagattag tgaagaggca gtacttgctg
    40861 taaaaaaagc tgtagatttc cttggaaaag aagggcatga tttgacagag attccttacc
    40921 cactagatgg tcgtaaactg atcacgtctt attatcagat gaatggcgca gaaacagcag
    40981 caatgatccg ctcgattgaa acaggcatcc agcgagctgt cagaaaagaa gaacttgaac
    41041 ccatttcttg gactttgttc caatatggtc agaagctctc tgccgctact tacatcgatt
    41101 ctctgcatgt atgggatgaa gcagcaattg tcatggaaaa cctacatcaa gaatacgatc
    41161 tattcctttc accaacgact gcatttaccg cccctaaaat cagcgaagat ttgcaaagtg
    41221 atgcgataag agcacagatg gaacacatca gtgattgttc tgaagtagaa ggtttagacg
    41281 ttgtttcttc catgtttgag gagagcttga agatcacacc ttatacacag ttggctaatc
    41341 tgactggaca accagcaatc agcttgccta ctcatttgac aaaagaaaac atgcctctag
    41401 gaatccaatt tatggctgcc agaggaagag aagatttgct atttcaaatc ggctatctat
    41461 ttgaagcaaa tcatcagttc catttaccaa atccatggaa atagcagaaa caaggagaag
    41521 aagaatgaag aaaaaaagat tgtttgctct aataactagt gcctttttta ttttaagcgc
    41581 ttgcggtaca gctgccgcta atcaggaaga taacagctgg agtaatgtag aaaaaaagaa
    41641 agaattagta gtagcgactt ctggcacact gtttcccgca tcttattata atgatcaaaa
    41701 tgaattagtt ggttatgatg tagatttggc aaaagaggtg gctaaacggt taaatgtcaa
    41761 aatctccttt aaagaataca acgtggatgg acaaatcact tctgtttcaa aaagagaatc
    41821 agattttgct gcgaacgatt ttggtatcac aaaagaaaga gaaaaaaaat tctccctttc
    41881 agagactttc aaatattcat ttgacagtat gatcgtacga aaaaaagatg attcaggaat
    41941 ccactcactt gaagatctta aagggaaaaa agcagctggc gaacccaata ctagctatat
    42001 gcgtttagcg gaaaaacacg gagctaaatt agtcacatat gacaatgcca cgaatgatca
    42061 gtatttaagc gatgtagcaa atggtcgaac agatgttatt ctaaatgatt attatctgca
    42121 gaaaatggcc gtatctgctt taccagatat ccctgtaaaa atactggaga acgtttattt
    42181 caatgaaaac gaaagtggtt ttttattgaa agaaggaaat gatgctctga aaaagaaaat
    42241 cgatggcgta ttaaaagaga tgaaagaaga tgggacgaca aagaaaatat ctgaaaaata
    42301 ttttcaaact gatgtttcag tcaaaccgaa agaaacgatg gctgagtcgg tgagtgagtg
    42361 atgtactttc ccctaattga tttttccctc atgtggactt cacttccttt cgtactgcaa
    42421 ggcttggtat acacattagg gattggcttc gtgtcgtttc ttttaggaaa tttggtaggg
    42481 ttgcttttga cagttttagg tcttttggat tggctgcctc tgaatgtatt tattcgtttt
    42541 tatttatcgt tctttagagg cattcccgca ctagtcctgc tgtttctgtt atatttcggg
    42601 ttaccttatc aattaagtgc cttaacggct tcagtcatct gctttacgat taccagcagt
    42661 gcatttattg gtgaaatcta tcgaggatca ctagcaggcg tttcttcagg tcagtgggac
    42721 gctggtttag cttctggttt ttctttcttt ggggtattga aatatatcgt tttgccgcaa
    42781 gcttttcgaa tctcagtacc ggcactcagt aacgtagcta tggatctagt gaaaggtact
    42841 tcgttagcag caacaatcac agtgccagaa atatttcaaa aagcaaagat cataggcggt
    42901 cggacattcg attatttttc tctctatatt ttagttgcac tgatttattg ggtcatttgt
    42961 atcgggatcg aaaaagtgca acagtattta gaaaaacgtt ctatccatca gtcaatctga
    43021 aaaatagaaa tggtgctagc gtggctggca ccatttctat tttttgtttc ttgtatattc
    43081 tgcctagtat tttaaaacca tttcatgtaa aatgtaaatc gaaaatatgt tcggaggtag
    43141 aaaacatgaa gaccccgcta accatcgaaa tagaatcctc gttataccaa tattgcatcg
    43201 agcaaggcgg cttggttgta gaagaagtca cgatgcctga tgaccaagga attgtagata
    43261 cgcttagctg cttgacaaaa tttgatggaa gccgagaatg gcgatgctat gagctgaaag
    43321 tgacaaaagc agattttcgc tctacagcca aactgtcatt tgttggacat tataattatt
    43381 ttgttttacc aagtaaacta tatgaagaag taaaaactga aatccctaca ggaataggtg
    43441 ttttagtgta tcgtccgtac acggttgaag aggagatgcc tgcctctggt acatttctga
    43501 ttgcgaaaaa agcagcaaag aaagagcttg ctgtaccgga agaagctttg acaaaccgct
    43561 tcatggcttc tttattcagg gaagtaagaa aagcaaagca aatggagcga ggcgtaaaat
    43621 attttccaac agatcaattg tacaaagaat tgaaaagacg ttcagaaaat caagatccat
    43681 tttctaacga acgatattat gaacggtttt tagaggaaat agctagtcag gcaatcaatg
    43741 agttgcaaga agaagttatc gcgcttcagc atgattatga atatttgagg caacaacagc
    43801 agatccgtcg gttgcctaca gagccattgg agtgaaaaat atgtactatc cttatttaag
    43861 aggaaaacaa tttgacctat tagcattaaa agaagcactg tcgcgaggat tgctctccaa
    43921 taaaatccaa ccagtgatcg aaccagtacg tgattccgct acgcttaaaa atgtgatcga
    43981 attatttcaa aaaaagcacc atccaatcgc tgtgatccaa aatccccaag taggacaatt
    44041 caaattattc gatcagcatg tgcacagttg gacagtcaaa gaaaatagct ctgtcgtccc
    44101 tgcacagatc ttaacgccag aaaatctcag tgaagtactg gattcacctc cagcgtttct
    44161 tgttttcgat ggacagcact acccaaaaga tacagaggtg tggaaacagt tggcaggagt
    44221 tgattcgaaa tttttgatac cagatactag tcgctttcgc atctggctgc ccgaaaacaa
    44281 aattgtgatc cgtgactctt ttcaaacgag aaagcatgtt gaaagttatg cagataaaac
    44341 agatgacttt tttagtgatg actatctttt tttccacgca gacggatata ttggattttc
    44401 tgatttcacg atcgaaggta gccgttattt cgataaaggg ttccctagcc gagcgcttgc
    44461 tatccatcta acgtatattg atgcttacgg caatatacgc gtgaaacatt ttgtctctga
    44521 cagtaacgac tctgctaaag accaagcatt gaagtttctt gaagcaggag ataaaatgaa
    44581 aaaatggatc atgcgtcacc atcatcaact cttgattact tcaggaatga ttgaattatt
    44641 ggctctttac cagcaacaaa aattccctgg actgggagtg ttgaaaaagt ggtcacttat
    44701 gcatcatttg gaacttatta gtcacctgct agatcatcca aaagattggc ttaaatatta
    44761 ttcaaaagtt caggaactat atgaagtgat ccaatgatta gataatgtaa atgaaaaagg
    44821 aatagaaaag aggaaactgg atgtatattc ggcaaacaag gaaagaagaa gtagaagaag
    44881 tggtagaaat cattaatgcc gcagcggatt tcattgcttc gcaaggctct cctcaatggc
    44941 aaaacgggca gaaaccaaca aaagaaacga ttttgaacga tattgaaaga aaagaaagct
    45001 atgtattaat agtggaagat caaattgctg gaacagctgc attagtctca agcgtggatc
    45061 ccgtttacac aaaaatagat ggtagttgga aagaatcaac tggtccttat ttatcgattc
    45121 atcgtgtcgc tttagcagaa agtactcgag gaaaaaaact agcaaaaccg ttcttagaac
    45181 atttgttgac gattgcagcc agcaaaaata tccaagatat ccgtatcgat acttatccag
    45241 ctaatgaacc gatggaaaag accatctatt ctgctggatt cacttatcaa gggatgattg
    45301 aatttccttt tgaacacggc gaaagaaaag catatcaaat aatcatcaat tgactataaa
    45361 atcatctgag caaagataaa gacattaaca ctactgaaaa aaacaatcat atgatagcca
    45421 agaggttgta acagaagtgg ccagcttcaa aaaacaagaa agaatttccg aaaatgcttc
    45481 tcaaattttt gtggaatttt agcgtatttt acgaaatagc tgctttctga aactcccttc
    45541 atcgagaggt cgtgacatag cttttgtcac gacctctcgg cttatcctac gagtattatt
    45601 cgatacattt atatcaataa tccttttttt attttatctg cagcttcttg gaacgctcca
    45661 tcgtttgaca cgactaaaag tgaggggata gctttcaaac gtttcaactg tgctaaatct
    45721 tctacataaa ccgccagtct ggctgaaatc tgttcagatg aatctccacg ttttttcagg
    45781 cgcgattgca atgtttcttt agagatcgta ataaagatag gacggactac cgtcccgaaa
    45841 tactcatata aatgccaaaa accatttgct gtcaaaacgg cgtaacaatt tcctactgtc
    45901 agtttctttt taatttctgc tttactggaa ccatatttat gttgagcata ttggtcccac
    45961 tctgcaaact catttccctt gatcatctga ttgaatgtat tgtcagaaac aaaataataa
    46021 tcctcttgat ctttttcccc aggtcttggt gatcgattcg tgtaagtaat gatcttttgt
    46081 tccggctgaa aaatagcttc tgcgagtgaa gtttttccag aaccagaagg accgataaat
    46141 acatagcaat aattcattgt catttctcct ttgatgattg aacaagtgaa aaagctttgg
    46201 aaaatatttc caaagctttt aaaagtaact ttgctttttt gtattttata ccagcaagcc
    46261 agtcacaata gcacttaaaa agctgactaa agtcgctgtt agcaaaattt tcaatccgtg
    46321 ttttgcgaca agatttcctt tttcttcatt taatcccttc atcgcaccag aaatgatccc
    46381 gatagaagag aagttggcaa atgaaacgag gaagacagat ataattgctg ttgtacgctc
    46441 agtaaaatgg aaattaccat ttgctaattc tgtcatagca acaaattcat ttgtaaccag
    46501 tttagtcgcc atgatactac cggcatccac tgcttctttc catgggattc cgctgatgaa
    46561 ggcaagaggg gcaaagatgt aacctaggat ctcttggaaa gtgatgccga atatcccgtg
    46621 gaagatagca ttgatcatgg caatcaaagc aacaaaaccg ataagcatag cagcaaccgt
    46681 gatcgccaca tggaaaccat caagaatgta ttctcccaac atttggaaaa atgtctgttc
    46741 tttgttttct tcaatgatca gctcatcttc tttttcttct aatacatagg gatttacaat
    46801 tgaagccaga atataaccgc caaataagtt caaaacaagg gcagtgatca catatttaga
    46861 atcgatcagt gccatataag atccgacgat cgacatagaa actgtagaca tagccgatac
    46921 actcatggtg aacaaacgtt tctcagatag gaagggtaat tcctttttta tggaaataaa
    46981 aacttccgat tgtcctaaaa tagcagaagc tactccatta taagattcca atttgcccat
    47041 cccgttgatt ttacttaatc ctagaccaac agctttcata aataatggaa gaatcttgat
    47101 atagcgtaga ataccgataa tagcagaaat aaatacaatt ggcatcaata cggaaagaaa
    47161 gaaaggtgca cttcctttat ttgctacacc ggcaaaaaca aagtcaacac cttgcccagc
    47221 aaaagcaaga agatgatcaa acatttttgc caatacagaa acaaccgctg taccaaaagt
    47281 tgtacgtaat aatacgaaac caagaacaag ctgtaaaacg aacatcacaa ttagtggttt
    47341 caatttgatt gcttttttgt tactgctgat caaaaaagca agccctaatg tgacaaataa
    47401 accaataata cctaataaat aactcaaata atcactccta ttccaaattc cgttttattt
    47461 tacctgtttt gcaaataaaa tactaatctt tagtgaaatt ttcattactt ttttagagtg
    47521 aaacgcattc attttccatt agaaaataaa gcgaacaaaa taaaaggttt aaaaagtgta
    47581 acgtcttagt aaagtctata aaaaaacgaa actatcgatt aagctaatag tttcgttttc
    47641 aacatttata agtaaacttt ttctattggt aatatagatt ttcggaaggg tagacaggtg
    47701 cgcaggtaat atcgattcct agttttttca atgtttgttc atcattttta ttgaccatca
    47761 cagtagagtg ggcttgtgct ccctcaagtt cagctagttt atcataagca acttgagcga
    47821 ttggattcgt tactgcactg attgataaag cgatcaagac ttcattgatg cttagtgcat
    47881 ccaaagagga atgaagtgtc tttgatttca atccttgtat tgtttcaaga actaatggtg
    47941 acaataaagg aatgtcatct gcgatatggg ctaaatgttt tactgcattt aagataactg
    48001 ccgctgacgc atccatcaat gaacttgtac gcccggtaat gatgacttca tctggtaatt
    48061 cgattgcaat cacagcagaa ggatcttttg taggactttg cgcttgaatc ttatctgcat
    48121 agtcatgggc agggactacc acgtttcggt cttcaggacg taaaccgact tcttccataa
    48181 tcagtttgat tcgattaact gcttcttcgt cgatcaatcc ttttttgaag tcgcattctg
    48241 tttggaaata acgacggatg atttcttgtt tagaggcttc ttggacaacg gtatcatcca
    48301 cgatcccaaa tcctacacga ttcacaccca tgtcagtagg agattgataa acagattctt
    48361 taccagtaat tttttcaata atacgtttga ttacaggaaa tgtctcaaca tcccgattat
    48421 agttcacagc tactttattg taggcatcaa agtggaagga atcgatcata ttgacatctt
    48481 ttagatcgac tgtggctgct tcataagcaa tgttcagcgg atgtttcaac ggaacattcc
    48541 atactgggaa agtttcgaac ttggagtaac cagctgcatg tcctttttgg ctttcatgat
    48601 acagttggtt caagcaagta gcgagctttc cacttcctgg gccaggagct gtcactacaa
    48661 cgattggttt agttgtttca atatactcat tttttccaaa accatcttct gagacgattt
    48721 tttctacgtt gactggatag tcttcgattt ctgagtgttt atagaccttg atgtttcgtc
    48781 tttctagttt attgataaag actttcgtgg caggctgtcc actatagcga gtgataacga
    48841 cactgttgat taataagcca taaccacgta attcatcgat taaccgcaag atatccatat
    48901 cataagtaat cccataatca ccacggatct tattacgttc aatatctcca gcatagacgc
    48961 aaatcagtat ttcagcttga tctttcaatt tttgcagcaa tttgattttc gcatcttctt
    49021 caaatcctgg aagtacacgt ttcgcatgct tgtcgtcaac taacttccca ccaaattcta
    49081 aatataattt gtcatagtgg ttcactcgtt ccaaaatata cgctgactgc tcttcaatat
    49141 atttttctga atcaaaacca atttttttca ctaggttccc tccttaagta ctaaagcatt
    49201 ttttcatttt tttgaggatt cgtcaactgg aagagcgaaa ttcctcaaaa aaacaaagaa
    49261 aatggtttaa accaacttgt ctagatagtt attcattggt atgatagttt ttgataagga
    49321 aggtgctaca tgaaaaaaag acagaaaaag aaaaacgcat ataaacacta tatccgttcg
    49381 atttttaccg gttatgaaag aatgcttgaa gatcccgaat tggaacaatt gacgtttact
    49441 tatctaaacg aagaaacgca gctaactcgt gatgagcatc agcgcattca tttcacaaca
    49501 agagatctgc ctagtaaata aaaaataaga taaaggtcat cggattcgat tctgtcctat
    49561 cagatggaaa gactagttga tcgaaaaaaa ggctgtacca aattttggtg cagcctgttt
    49621 tatggagcat tgcccgctct tttttataac aattttttac agaaaatggt actattgaag
    49681 tattaataag tgaaaaacag atgagtaaga ggaggcaagt agtatgaaag agccagatac
    49741 aaatgcaaat tatgagccag acgaactaga ggagacgaat gcggatcagg atacaggaca
    49801 agaatcgtct tctttttacg atatcaaaga aaaagcaagc atgaatcttt cccaattatt
    49861 agaagactta caggcttttg aaaaagctgt ccgcgaagaa gatatccctg agatctaccg
    49921 tttatacaat ggccgattga atgaagaatt aaaaagaagc tcaaatgaaa atcacgagat
    49981 cgatcaattg ctgatgcgta agatccatga tcgtttttta caggaatttc cttttatgga
    50041 acaagtagaa aacatctcgc caacgatgag ctattacaaa atcggcactt attaccatga
    50101 tcggcccacg gtcggtattg atgcaagtct gccagaaatt tttgttttgc ctaagatcga
    50161 tgaagagtgg gagaaatatt cccaaccgga gtcaacggac tatgacaaaa aaatcaatga
    50221 gctagacgca aaggtgatca ctgctcagac agaaattgaa cgtttagatg aacaaataaa
    50281 agaaatcaat cgacaaatga ctgatttgaa cgacaataaa ggattcttga atcgtaaaaa
    50341 aatcgaggaa gaaattcaag aattagagaa gaagaagcaa gtactatcta atgaaaaatt
    50401 aggctggctt ccttatattg agacgcctga aacaatccag cagcaaaaag aagcattgaa
    50461 gcaagaagca agagcagacc agcttcgtgc agccatcgta gaaaaagaac aaaggcaaat
    50521 cagacgctat ttcggtagca aagagggatt cggtcaagca atccatgaat tcttgatgaa
    50581 ttatcttggc aatgagaatc ctaataatca atctaatgaa ggaggttccg agtatgaatg
    50641 aacacgatga agcagaatgg acaaaaaatg aagaacaaac agaagatcat gaagaaacga
    50701 acacttcatt ggaagaacaa acaagtaatc ctctggatga cacagaagaa atccctatgc
    50761 tagaggaaac aaaaatacac gaaaaagaaa aagtaactcc gacgaatacg aatactgcag
    50821 aaaacaccca tgcttacgaa ataactgaaa atcccgggta tttagaagga aaagagcaag
    50881 atcatcaaga tatcgtcagt ttgattgaaa cagcggaagc agaattagcg gatttacgta
    50941 tgagaaaaga tttgatcgaa tcagattttc cacaattatt agaatcatat gatcgtttta
    51001 tattgaatga agaaccaatc tccacgatcg gaaagacaag cctgatcgaa tacttcacgt
    51061 atgaattact gaaaccgttg aatgatattg gtctggaacg gtcaaattca gcttatgaca
    51121 catggaaaac aagacatttt tcgatcaatt atacgttgaa tggacaaaac gaattagtct
    51181 tttcctttgt attaccgacc atcgatcaac gataccaagt ggaatcgatg agtctcctaa
    51241 acgtatcacc agagacaatg gaaatcaatg tccaagatga ccgggtgctt tctttgatcc
    51301 gacactggtc agtggatcga gtattctctg cagggcagat cacgatattc aatcacaaat
    51361 tgaatcaatt attagcccat gcaagaacac ttggttttac cgttaatcag acattactag
    51421 acaatacgaa gccacttcgt ttgaatcttc agagcgaatt tgaattgacg aatgaagtat
    51481 tggatgatat ttttatcgtg gcaatgaaaa atccatccta cgatatggaa aagatcaacg
    51541 aaactactta tcaagtacga ttagataaag gacagtcttt aacgataaca acaaacgaaa
    51601 aagatcaaac agtcttgtcg atctcatctg gagactaccc acgatctgtc attgatttct
    51661 ttatcaatta cgaattcttg gtcccattaa tggtgagaaa gtcctgattg gataagttgg
    51721 attaccagat gtcattcaga taattctgtt ccaaaggact tgcggcagtt atccagaata
    51781 attgtcacaa gtcttttctg tatgtactaa atggacgtga ataacttgct gatgaaggag
    51841 ggatttcatt aggaatgtcc acaaataaaa tagcacagct tagcttattg tctgctgctt
    51901 gtgtagcagg taggatcgct tttcaattta ttccgaattt ccagccaatg actgctattt
    51961 ttttatttat agtactttac ttaagcttaa aagatgcgtt aattgtcatg agtctttcta
    52021 ttgcgatcag cagtttttat tttggtgttg gaccatgggt catcggccaa tggatcagct
    52081 atactgttgt tctgagtttg ttttcaatcg tctgcttgag aaaaacagtg caaaggaatc
    52141 tatggttaaa gggagtctgt ttttttctgg cgggcatggt ttacggaata ggtatgaccg
    52201 tttttgatac gctgttatat cgtttgcctc aaccttggat ctattacctt caaggggtgt
    52261 cgtttgattt gatgcacagt ataggcaatg ttgtgttctt tcttgttttt ctgccagtcg
    52321 tcaaacgttt ttacaatcat tcaggaggaa aaaatgaaaa aaataattta tagtttgctt
    52381 gcaatgagtg tcagtatact cattttgaca agttgcagta caacctatac acaatcggct
    52441 tccaaccaaa aggaggaagt aaaaacatcg caaaaagcaa caatcacgtt acaagaaaat
    52501 ggtcaaaact tttcggaaaa agaagtggtc ttcaaaaaag gcgatgattt actgagtatt
    52561 ttgaaacgaa attttgaagt caaagaagat aacggcttca tcacttcgct tgaagggcac
    52621 tcacaggatg agaaaaatca actctattgg atgtttactg tggacgggaa aagtgctact
    52681 actggtgcca aagagatcaa attgaatgat ggacaatcgg tcattttcaa tttgtctaaa
    52741 ctataagttt cataaaaaac tgttaaaggg cgaatattgc cataattcag tgagttcagt
    52801 tgatgaaaga aggaaaataa catggaaaat tttaaaaaaa gcggaatgtt ttccgtaatt
    52861 gctgctctag gggctaatat tctagttgct atcagcaaat ttgtcggcta tgcaatcagt
    52921 ggcagtgccg ccatgctaaa cgaaagcatc cacagtatcg ttgattgcag caatcagatt
    52981 ttgctgttat tcggtgataa acaagccaat aaaggacaga gcgagttgca tcaatttggt
    53041 gaaggacgag caaaatactt tttcagtaca atcgtcgcaa tgatgctttt cttcggcggt
    53101 ggggcacttg gggtgatgga agcttttgaa aagttgacgc atccatccca tgaagtgggt
    53161 aatccgatca ttgttatagc aatactgtta tttggtttgg taatcgaagg aagttcgtta
    53221 cgcgtggcaa tgaaagaaat caaagaattg aatactgaaa aactttccac gatgcgcttt
    53281 ttgcgcgaaa gtcgacacag tgaaatactg attattttta cggaagactt gtgtgctgta
    53341 atcggtttgg tcttggcttt agcaggaaca atattgactt atgcaaccgg gattgctgca
    53401 tttgatgcga tcagcggatt gctgatcggt ttcttgctga tgggagccgc cattttccta
    53461 gcaaaagaat tttatagtct gatcatcggt gaaagcgtga cagcaagcga tttatcaaaa
    53521 atcaagttag cttttgaacg tcctgagatc agtcggctga tcgatataaa aacagttcat
    53581 ttaagtccaa cggagatttt agttgcagca aaagcagata tcgttggtaa caaagagaat
    53641 gaagcttact cggtcatcaa tgatattgaa aaaaatatgc gtcagtctct tcctgacaag
    53701 aagatgtata tatacattga aacagataaa tatgacccaa attattctcg taaataaaac
    53761 gtttattcat gaattgaagc aaaaatgaga aaaatataat cttgttttta aataaaacgg
    53821 ctacaattta gcgaatttat gttacaatga gtccgctgtt tatttgttgt aattaaagga
    53881 gatattttaa tgaacaaaaa gaaaagtgcg ccatggcttc aagctttgca tgcagtgatg
    53941 ccactttgta taagctatat accagtagga ttagcttgcg gagtattgtt gcaaaaagtt
    54001 ggatttgatc ctctcttatc aggactgtta tcgattctgg tcttttccgg tggcgcgcag
    54061 tttttagttg catctatgct tacgacgcaa gcatcatttg caacgacatt attgatggtt
    54121 ttctttttag aattacgcta tacattatta ggagcaagtc ttgccggttt tatgaaaaaa
    54181 gaaaagcgga cgtttttggc tgtcttttct caatcactga atgatgaaaa ctatgcggtg
    54241 aactacttaa agttttcaac tgacccttcc tggaataaaa gaaaggcttt atatgtcaat
    54301 tggttctcaa tgactgcatg ggccggtagc aatatgatcg gtaatttttt cggctcggtg
    54361 attcgagtag atgctgacct tgtccatttt gctttgacgg ccatgttcat tttcatgttt
    54421 atcatgcaga tgaaaagcgc actactgatc tttacaggtt tattctcagg cgtattaggg
    54481 gtcgtattca tggtattatt ccaaaatact ttcggattga ttgcagcaac agtcattgct
    54541 tcatttgccg gatttatgct ggagaaggca ttcaaaaaag aaaaagctaa gaaactaaga
    54601 gaccgcggta aagatgtcaa tgagccgctc ttcaacttcc cggaacagga ggccaatcac
    54661 catgactaaa ctatatttgc tacttttagt tgcttgtctg ttcatcgtgg catatatccc
    54721 gcgcttgttc ccgatgcttt attttactca tcgaaaagtg ccatcctggt tcagtgactg
    54781 gatgaaatat gtaccggtgg cattatttgc ggcgttagct tttaaagatg ttttcattac
    54841 tcatgaacat ctggatattg cttggaatat caaaatagct gcaatgattc tagtagcagg
    54901 cgtggcttac aaaacacgtt cgatggcgtt gtcagttttg acaggacttg cgtctgtctt
    54961 tttgctgtct atgctttaaa ctgttttatt ttattaaaaa cagagattgc gacataagtt
    55021 gttcaaactg atctatccga actgcatttg caacagtcaa ttctggatgc aagtttattc
    55081 gtagggataa aaaagattag tgttggctta tgatgcaagc tcttttttat tttaggaatt
    55141 agagagggat ttgtccttct atgatttttt gctataatag ggaagatgtt tattttatga
    55201 aagaatagtt gagggaattt aaatgaataa aaaattgatg caaggaacat tttggctaac
    55261 ctttgctaat cttctatgta aagttttagg ggtagtctat ttgattccct ggctaagtat
    55321 gatggggaac aatcaagatg gtatgcttgc tacgacattg tataatgttg gctatcttcc
    55381 ttatggattg ttcctgatgc ttggtacagt cggatttcca aatgcgattg caaaaaaagt
    55441 agctgtagcc acaaaagaag gagataacgc tgcttgtcgg ctgattttta gaagtacgat
    55501 caatatcatg tttgtcatcg gtatcgcctc tgctgcactg atgtatttat ttgctccttt
    55561 actagccgga atcagtccga ttgctaacgt taataatggg atactagcta tcagaagttt
    55621 atgcccatct ttgattgcta tcccaattct tagtgcaatg agaggatatt tccaaggaaa
    55681 aaatgatctg cggccttatg gaacttcttt gattatcgaa caggctgtgc gagtgatcgt
    55741 tatcttggct ggtacttatt acttgcgcgt attgactgac ggaaccatat tagaagctgt
    55801 attgatcagt acagtcgctt ctttcttcgg tgggttagct gcgattatcc atatgtatat
    55861 cgtcggacgc agaaaagact tcttcgaact taaagatttt ttgatttcca gccgttattt
    55921 cgaaagagaa aaccgatctg cctctgtctc tatcattcgg gaaacactac cgtttatttt
    55981 tgtcggctca gtcattacta tcgttcaaat gatcgaccaa gtaacgatga aaccactgct
    56041 tcactttttc cgtccagaga tcgcagatca gcaactggaa ttcttattca gccgtgcttc
    56101 tgtcaatcca aataaattga cattgatcct gatctccatg gtaggaacag tagctataag
    56161 cagcttgcca atattaagca cgatgaagaa aaaagatcgg atacaaatcg aaaaaacagt
    56221 aggagatagt ttttcgattg cgttattgat tcttcttcct tcattgactg gaatgtcttt
    56281 attagctgga ccactataca cattgttttt tggctatgat cctgaaagtg tcggatattt
    56341 ccaaatggct ttgctagctt ctttgttttt ctctttattc acgatcctat ctacgatgct
    56401 tcaatctttg aatcaccatc gttttgcgat ccgattaact gtagaagcaa ttatcctgaa
    56461 agtcatcttc caagtaatcg gattaggatt agttggcgga tacgggatga gcttatcaaa
    56521 tggcttagca ttcggtattg tctttgttcg cggctatcac tttatgtgca aagaataccg
    56581 aatagcacct ttagcaaaga tcagcaattt tttcttaaaa actttccgct ccaccctgat
    56641 tatgcttgca gtatgttttg ccgttttctt tttgctgaat cagcgattgt caatggaatc
    56701 aaaaagctat gcaatgattt attgtgtggc tgtaggaagt attggcggct tagtattttt
    56761 attttctcaa ttcggaaaaa atgggtttcg aatgttgaaa aatgttaaac atcatagcag
    56821 aagcaaagaa taggttaact aatcgttttt tgctgtcact tgaaaaacgg caactcgtat
    56881 gattacgctt gtcgtttttc tattttccaa ttttagtttc atatctaatc ttacttatga
    56941 tatagttata aggtctggaa aaattctttg aaacgaggaa attaaacaca tgaaacttgc
    57001 agtagttaca gatagttcgg catatctgcc ggaacgtatc aagaaccatc ccgacttatt
    57061 cgttattcca atccctttga ttatggatgg gaaaatttat aacgaaggaa tcgatatcga
    57121 agcggatgaa tattatggac ttttaaaaaa cagtaaagat tttcctacta cttcacaacc
    57181 tgtcgtaggg gaagttttgg gtttatatga ggaattgaaa gagaaagggt atgacacgat
    57241 tttaagtatc catctttctt cagggatttc tggctttgtc aacacattat ttgcgatgaa
    57301 agatgacatc agcggagtaa cggtcattcc ttatgactct aagatcacta gtatgccgat
    57361 gggacacatg gtagaagctg ccttagactt aaatgatgaa ggtcagtccc ttgatgaaat
    57421 acttgcacat atcgatcgaa tccgagataa tacctatgct tatctgattg tagatgattt
    57481 gaacaattta gtacgaggag gacgtttgac aaatggtgca gcgctgattg gcagcttatt
    57541 aaaaatcaaa ccgatcctga cattttctga agggaaaatt gttttattcg aaaaaatccg
    57601 ttcaagtaaa aaagcatttg ctcgagctga agaaattatt ggtagaagaa ataacgaaat
    57661 acaaccgcca gtcaaacttt acgtgataca tgcaaataat ttagaagtag cgattgcgga
    57721 gaaagagaaa ttgcagaaaa aatatccaaa tgcagaaatc gaaattggtc atttcggacc
    57781 agtcattggt acacatttag gtgaaaaagc catcggcatt gccatttcag cgcaataatt
    57841 ccttttattc aaaaaacata ccaaaaata
//
LOCUS       DBBGSZ010000016        54993 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.016, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000016 DBBGSZ010000000
VERSION     DBBGSZ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 54993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54993
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.016"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..1087
                     /locus_tag="ACIZE5_001319"
     CDS             <1..1087
                     /locus_tag="ACIZE5_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6108472.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1305..2447)
                     /locus_tag="ACIZE5_001320"
     CDS             complement(1305..2447)
                     /locus_tag="ACIZE5_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6108473.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2452..2637)
                     /locus_tag="ACIZE5_001321"
     CDS             complement(2452..2637)
                     /locus_tag="ACIZE5_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HGC6108474.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(2991..3236)
                     /locus_tag="ACIZE5_001322"
     CDS             complement(2991..3236)
                     /locus_tag="ACIZE5_001322"
                     /inference="COORDINATES: protein motif:HMM:NF024059.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6108475.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3230..3631)
                     /locus_tag="ACIZE5_001323"
     CDS             complement(3230..3631)
                     /locus_tag="ACIZE5_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGC6108476.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3818..5626)
                     /gene="uidA"
                     /locus_tag="ACIZE5_001324"
     CDS             complement(3818..5626)
                     /gene="uidA"
                     /locus_tag="ACIZE5_001324"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HGC6108477.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(5649..7415)
                     /locus_tag="ACIZE5_001325"
     CDS             complement(5649..7415)
                     /locus_tag="ACIZE5_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
                     /protein_id="HGC6108478.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(7428..8222)
                     /locus_tag="ACIZE5_001326"
     CDS             complement(7428..8222)
                     /locus_tag="ACIZE5_001326"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC6108479.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(8232..9608)
                     /locus_tag="ACIZE5_001327"
     CDS             complement(8232..9608)
                     /locus_tag="ACIZE5_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6108480.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            complement(9728..10375)
                     /locus_tag="ACIZE5_001328"
     CDS             complement(9728..10375)
                     /locus_tag="ACIZE5_001328"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HGC6108481.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(10459..11886)
                     /gene="uxaC"
                     /locus_tag="ACIZE5_001329"
     CDS             complement(10459..11886)
                     /gene="uxaC"
                     /locus_tag="ACIZE5_001329"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HGC6108482.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(11960..13039)
                     /gene="uxuA"
                     /locus_tag="ACIZE5_001330"
     CDS             complement(11960..13039)
                     /gene="uxuA"
                     /locus_tag="ACIZE5_001330"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HGC6108483.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(13042..14673)
                     /locus_tag="ACIZE5_001331"
     CDS             complement(13042..14673)
                     /locus_tag="ACIZE5_001331"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HGC6108484.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            14977..15648
                     /locus_tag="ACIZE5_001332"
     CDS             14977..15648
                     /locus_tag="ACIZE5_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6108485.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
     gene            complement(15808..15999)
                     /locus_tag="ACIZE5_001333"
                     /pseudo
     CDS             complement(15808..15999)
                     /locus_tag="ACIZE5_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
     gene            complement(16367..16708)
                     /locus_tag="ACIZE5_001334"
     CDS             complement(16367..16708)
                     /locus_tag="ACIZE5_001334"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108486.1"
                     /translation="MSIDDCLEEQIRLFLKFLKVKVQNNYFTCYSYAHPVLNSLPFNS
                     LVQGLITNIVLLVCTPNEIFVKKIGSGISSVRLKEKEYTQKIIHIPKPEIKRFEIKDY
                     SALGLFSIGYW"
     gene            complement(16805..17257)
                     /locus_tag="ACIZE5_001335"
     CDS             complement(16805..17257)
                     /locus_tag="ACIZE5_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108487.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(17264..17812)
                     /locus_tag="ACIZE5_001336"
     CDS             complement(17264..17812)
                     /locus_tag="ACIZE5_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HGC6108488.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            complement(17857..18189)
                     /locus_tag="ACIZE5_001337"
     CDS             complement(17857..18189)
                     /locus_tag="ACIZE5_001337"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108489.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(18203..18460)
                     /locus_tag="ACIZE5_001338"
     CDS             complement(18203..18460)
                     /locus_tag="ACIZE5_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108490.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(18655..19197)
                     /locus_tag="ACIZE5_001339"
     CDS             complement(18655..19197)
                     /locus_tag="ACIZE5_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF0163 family protein"
                     /protein_id="HGC6108491.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            complement(19218..20309)
                     /locus_tag="ACIZE5_001340"
     CDS             complement(19218..20309)
                     /locus_tag="ACIZE5_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HGC6108492.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(20317..22527)
                     /locus_tag="ACIZE5_001341"
     CDS             complement(20317..22527)
                     /locus_tag="ACIZE5_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HGC6108493.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(22543..25071)
                     /locus_tag="ACIZE5_001342"
     CDS             complement(22543..25071)
                     /locus_tag="ACIZE5_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC6108494.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(25123..25533)
                     /locus_tag="ACIZE5_001343"
     CDS             complement(25123..25533)
                     /locus_tag="ACIZE5_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpE family conjugal transfer membrane protein"
                     /protein_id="HGC6108495.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            complement(25546..25764)
                     /locus_tag="ACIZE5_001344"
     CDS             complement(25546..25764)
                     /locus_tag="ACIZE5_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpD family membrane protein"
                     /protein_id="HGC6108496.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(25761..26753)
                     /locus_tag="ACIZE5_001345"
     CDS             complement(25761..26753)
                     /locus_tag="ACIZE5_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGC6108497.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            complement(26832..27743)
                     /locus_tag="ACIZE5_001346"
     CDS             complement(26832..27743)
                     /locus_tag="ACIZE5_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGC6108498.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(27762..28106)
                     /locus_tag="ACIZE5_001347"
     CDS             complement(27762..28106)
                     /locus_tag="ACIZE5_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108499.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(28126..28404)
                     /locus_tag="ACIZE5_001348"
     CDS             complement(28126..28404)
                     /locus_tag="ACIZE5_001348"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108500.1"
                     /translation="MSVEHFCDCYIALLRSQQLLTVERYGAEFGYVLQAERHRATRCY
                     EKEDQVIDGYEELCIRNNRYLQQRLYEQLMMDFSNLYRGYECSMIQER"
     gene            complement(28763..29263)
                     /locus_tag="ACIZE5_001349"
     CDS             complement(28763..29263)
                     /locus_tag="ACIZE5_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108501.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            complement(29264..29809)
                     /locus_tag="ACIZE5_001350"
     CDS             complement(29264..29809)
                     /locus_tag="ACIZE5_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108502.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(29806..31062)
                     /locus_tag="ACIZE5_001351"
     CDS             complement(29806..31062)
                     /locus_tag="ACIZE5_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGC6108503.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            complement(31423..31734)
                     /locus_tag="ACIZE5_001352"
     CDS             complement(31423..31734)
                     /locus_tag="ACIZE5_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108504.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            complement(31757..33232)
                     /locus_tag="ACIZE5_001353"
     CDS             complement(31757..33232)
                     /locus_tag="ACIZE5_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HGC6108505.1"
                     /translation="MKAHFFKYRGRRIRYFNRYLWFCYYGFFLFPFLILLGWFSWKVF
                     YPRLSTFSNWQMYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLVRML
                     IDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGHLLS
                     EVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPNMLI
                     AGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEEMII
                     CLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDMEARN
                     RVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYLMTF
                     GEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYDFTV
                     KEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            complement(33681..34133)
                     /locus_tag="ACIZE5_001354"
     CDS             complement(33681..34133)
                     /locus_tag="ACIZE5_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108506.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            complement(34135..34500)
                     /locus_tag="ACIZE5_001355"
     CDS             complement(34135..34500)
                     /locus_tag="ACIZE5_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108507.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            complement(34599..38882)
                     /locus_tag="ACIZE5_001356"
     CDS             complement(34599..38882)
                     /locus_tag="ACIZE5_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HGC6108508.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            complement(39029..39268)
                     /locus_tag="ACIZE5_001357"
     CDS             complement(39029..39268)
                     /locus_tag="ACIZE5_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108509.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(39358..39600)
                     /locus_tag="ACIZE5_001358"
                     /pseudo
     CDS             complement(39358..39600)
                     /locus_tag="ACIZE5_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708076.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(39713..39949)
                     /locus_tag="ACIZE5_001359"
     CDS             complement(39713..39949)
                     /locus_tag="ACIZE5_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108510.1"
                     /translation="MFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTELKDKN
                     NVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            complement(40960..41871)
                     /locus_tag="ACIZE5_001360"
     CDS             complement(40960..41871)
                     /locus_tag="ACIZE5_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6108511.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            complement(42067..43902)
                     /gene="lepA"
                     /locus_tag="ACIZE5_001361"
     CDS             complement(42067..43902)
                     /gene="lepA"
                     /locus_tag="ACIZE5_001361"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HGC6108512.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            44049..45269
                     /locus_tag="ACIZE5_001362"
     CDS             44049..45269
                     /locus_tag="ACIZE5_001362"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6108513.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            45289..45783
                     /locus_tag="ACIZE5_001363"
     CDS             45289..45783
                     /locus_tag="ACIZE5_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HGC6108514.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            45761..46447
                     /locus_tag="ACIZE5_001364"
     CDS             45761..46447
                     /locus_tag="ACIZE5_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108515.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(46598..49207)
                     /gene="clpB"
                     /locus_tag="ACIZE5_001365"
     CDS             complement(46598..49207)
                     /gene="clpB"
                     /locus_tag="ACIZE5_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HGC6108516.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(49458..50504)
                     /locus_tag="ACIZE5_001366"
     CDS             complement(49458..50504)
                     /locus_tag="ACIZE5_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HGC6108517.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            complement(50515..50787)
                     /locus_tag="ACIZE5_001367"
     CDS             complement(50515..50787)
                     /locus_tag="ACIZE5_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HGC6108518.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            complement(50822..51730)
                     /locus_tag="ACIZE5_001368"
     CDS             complement(50822..51730)
                     /locus_tag="ACIZE5_001368"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGC6108519.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            complement(51862..53094)
                     /gene="pepT"
                     /locus_tag="ACIZE5_001369"
     CDS             complement(51862..53094)
                     /gene="pepT"
                     /locus_tag="ACIZE5_001369"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HGC6108520.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            complement(53109..54230)
                     /locus_tag="ACIZE5_001370"
     CDS             complement(53109..54230)
                     /locus_tag="ACIZE5_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HGC6108521.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            complement(54227..54928)
                     /locus_tag="ACIZE5_001371"
     CDS             complement(54227..54928)
                     /locus_tag="ACIZE5_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HGC6108522.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
BASE COUNT        16580 a        11367 c         8237 g        18809 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaaccac cggtggcaaa ccggtggcaa atccatgtaa
     1141 acatggttta ttttttacac tgttttcaaa caaacccttg ctatttcttc ggttcgtcct
     1201 cgtccatttt cgataccgac agctagctta taacccaagg tatatcaaca taaaaaaata
     1261 aaaataggct atgacagcag cgtgacagca aaaaagatgg aaagttaaat atcaaacctc
     1321 gtaatttcat ttgcgagtgc ttgatttgtt tctggatata agtgtccata tttgtccaaa
     1381 gtagttttaa tagaggcatg acctagacgc ttagatattg catagatatt tttattatgt
     1441 tcaattaaaa aggcaacatg cgagtgtctt aatccatgca tatgaattgg ttttactcct
     1501 gcaatttcag ctagtttttt tattctgctt aaaatagttc ttggagatgg cggtaatcca
     1561 tcaaaagaaa aaaccaattc tatatttttc ccaattgatt gttgagtttt tttccatgtt
     1621 tttaaatctt caacggtttg tctgtctaac gaaattatcc gaatacttga tgtatttttt
     1681 gtttcagcaa attcataatc ttgtcttgta cggatgtaaa ttgacttatt tacgctacat
     1741 ctgccattta ttaagtcaaa gtctttccat tgtaacgcta agagctcctc actccttaca
     1801 cctgtaacaa aaataaaacg catcaaacgt ttataaaatt cttcataaaa atccccgtga
     1861 taaacactat tatatacttt cttaaattca tcaactgtcc aaaattctac ttgaggacgc
     1921 tgagttttta ttttacctat agtatctaca ggattttctt caataatttc aagtacaatt
     1981 gcccttttaa aaactactct caacttattg aatatctgtt taatataatt tggtgataat
     2041 ggttgctcaa tgcccttttt tacaacatgg attttcgata aaaactgttg aaattcctgt
     2101 atatgaattg gtcgaatctt tacaacctgc atttctccaa aaaaatccaa tgcacgttgt
     2161 aaaatatgat ctgttttcat atatgttttt tctacagttc ccaacttata ccaaggaaaa
     2221 aaatactctc gataaaaatc atgaaacgtt attccttgca gataaattcc ttgtgaatca
     2281 gaaaaacttt gttttaactc ttcgagtccc cttctagctt ctccttgagt tttgaagcct
     2341 cttctggtca cttgaattct ttttccaaag cgatcttgtc ctaaagttgc agaaaaaaac
     2401 caagtgcctc tttttctgtc tttataaaca ttcgcaattt tcctcatttt actattcctc
     2461 ccaagaaata tggagaactt cttctaaaat tgaaatagga attcttttta tttttgaatt
     2521 acgataaaaa aagtatcctt tctcaactaa aagttcttta cattccttga agattttatt
     2581 agcatagtac tgagaaaaac ctagattaat caaatctttt cgagtagctg ttttcattat
     2641 agcaccttcc ttactttttt tcatttattt ctatcagctg cttttgtcaa aagcacatag
     2701 gaatttcacc tctccccaag tttacggcga gccttacgga agtatcatta tcccaacttt
     2761 aaatcatcgc tttttattga ctataaaaat tattttagaa tatttatcgc tccttcttta
     2821 cagcaagaaa tcatggcgca actaaaatat gctccttaaa gtgttaacgt actgatagaa
     2881 tctatttaat tttcaatgaa caataggttt tctacctaaa agaatctact aattccttaa
     2941 ctattagaag attcttttaa acagaaaaag tggaaagggg atttttttaa ttagttaatt
     3001 ttaaatttta agatcgcttc tattaattta atttctagct gacttatcat atattcatct
     3061 acataggtaa cgaattgacc tacctcgtta aatccatttg tcaaacataa cttagccata
     3121 taagaatgat aatgtttgag tatcatcttg atcgaaattg gatctccttc tagagcagat
     3181 aagataatgg atagtggaac taataggtac tgccgctttt tagatttatc taccataggt
     3241 cataccccat tttcaattgt tcaactgcct tctttcgttg ataccagata ccacttgtgc
     3301 tcatattgag aattttaccg atttcagcat cattaaaacc tgcaaaataa taaagtagga
     3361 taatctttct tcttatctcc gataactgat caattgctgc tgataacttt tgatctgaaa
     3421 ttaatatttc cattccaaat aagaaataga catcttgttc atcaaaatga gtttgggaat
     3481 acctgccttc atttgaatct gccaatggtt cctcattatc ctttatgtta gcgtttcgtt
     3541 ttcgaataga cttagcttcg tttcgtaata cttttttaca gtaggcatca aattggtgtt
     3601 gtatagatat gtcattgtaa tgttgttgca tgataatatg ctcctttttc cccctttcca
     3661 ctaatacaac aatcagaaag cccctttttt tcgaaaaaac tagaaaaaaa acataaaaat
     3721 atttatcatt ctttaaacag aaaatctttc tataaaaaac aaaaaaaaac gattaggcta
     3781 ggctaatcgt tttttgaaca ttcttaaaaa atccaaatta ttttttataa ctgaaattgg
     3841 gtattgatga ccatcgtttc tgtagatagt aagcaatcat tttaggtttt ctatctctag
     3901 taaagattcc tttcttattt ccttgcactc ttaaaatccc ttgacttgtt gcaaaatctg
     3961 caaaattcca cacttgttca ccaacaaaat tttcacatgt atctattact tcgtgatttg
     4021 cttcgtaata agccacttga tactcttctg taaacattgt tggtactgta tcatgaaatc
     4081 cagctactgt atctgctcca tattctgtaa acattattgg cgtatcagga catctttcca
     4141 tccatccatc tagctctttt ttcaacagat attttgcatg tgccagatcc cctcccgaaa
     4201 cataccaacc ataataacga tttaaacata aaacatcgac aatatctcct accttacaaa
     4261 catctggcgt tgattttaga taagtaacga ttgttacagg tcttttctgc ggatcaagtt
     4321 ctttagttaa ttcaactaaa ggttcaaaat attctttagc accttcggaa tccgaatctg
     4381 gttcatttgc aatagaccac attacaacac ttgggtggtt cttgtcgcgt tctatcaatt
     4441 ccttgatcac cgttttatga gaattttctg ttcgtatctc tttccacgta ttatgttttt
     4501 ccacattatc atctaataaa gtggccatga aatttaaatg taaccctact gcaggtactt
     4561 catcaataac tacaatacct tctcgatctg ctaatcgcat aatttcttct gagtaaggat
     4621 aatgtgatgt tctaaaagaa ttagcaccta tccatttcat taaattaaaa tctttaatat
     4681 ttacagcctc attcaaacca cgtccattaa catacgaatc ctcatgctta ccaaatcctt
     4741 taaaataaaa aggtttatta ttaatcaaaa atttgccatt ggtaacctga acactgcgaa
     4801 taccaaattc ttctgtatag gtatcgatca ctttattatc atcaattaaa ctaattttca
     4861 tactatataa ataagcgtct agaggttccc aaaaaattgg attcttaagc tgaatcattc
     4921 ctttctttcc ttcagcttca gctacaagtt gagcctcttc gtcatatatc gctattaaga
     4981 tttttccggt ccattctgta tcgatattga attctacact tgcatccaaa tcagttattc
     5041 ttgtattaat agtaatatca cttatatagt ctttcggagt tgtatataac ttaacaggtc
     5101 tatgaatacc tgcataattg aagaaatcaa aattaactaa gttttccttt tttatatccc
     5161 cattttcctg tactgtttcc ttcataatcc ccacaggtaa agtactatcg tcaataatat
     5221 tgtttacagc aactgtaatt cgattattcc cgtcttttac aaaccgatta atttcagact
     5281 caaatggtgt aaacccacct ttgtgttgag taataaactt tccattcaaa aaaacttttg
     5341 cttcatgtgt tgcagatcca aaacgaagaa ctaatctttc ttctaataat cttttaggaa
     5401 gagtcacttc tttttcatac cacacccatc caacatgatt tctaatgttc tctgtttcaa
     5461 ataaatcatt ataagaagag ggaactgaaa tcggataact ctctttttca tttattggtt
     5521 ctaaagcaag ttcttcctgt aagtcatcat ttgtatctaa tttaaatctc cagagaccgc
     5581 ttaagtcaat tacttgcctc gtctctgtca taatgggata caacatataa accactccta
     5641 tctaaatatt aaataaatgt atcctttaaa ccacaataag catctattgg acttactccc
     5701 ttaaattcag aaagacccat tagtttgtcc accaatattt ctaaagtttc ttgttttcca
     5761 tcataagtat taatataagt ctttacttga ggtacatcag ccaaatgaaa cggacactgt
     5821 acagatacaa aaattgttgg aatttcatga atgtaaaacg gtatatccgg agttccttta
     5881 cttgctggcc agacaattcg ttgaactgtg cctggattaa cattagctat attaatgatc
     5941 aagtcatatt ttttagttaa atttttaatt ggtctcttag cagcatatat tccagctata
     6001 tttttaattt tttcttcttg cgataatcct ttcaattctt cttcaggtga aatgtatttt
     6061 tcaacttcaa atccttttgc tgacaaaatc tgtttcaata aatcaatggc ttgaggtcta
     6121 tttccagcaa ctacttcacc aaacccacct tttaccccat gtacatctac tagtaaaatc
     6181 cttttatatt tttctggtac aataggccaa atatcttgtt tatctttaac taatgtaatt
     6241 gcttggtcag ccacctcttt aaaaattgat ttattttcaa ttaaaccaat tttttccaga
     6301 gcttcttgct taggtaataa aatttgttct tttgcttttt tgtgtaatcc caatttagct
     6361 tttaacccta aaattctttt taaggcatct aataaccgat catcagtgat aattccttta
     6421 cgatagcctt ccatcatata attaaagtct tcatctggat cattaaaaaa tagaaataga
     6481 tcacatccag ctgcaataga agtgggcaat aattctgatc gtttcattgc cccagtcatt
     6541 cctaacatat gactagcatc agtaactact aatccattaa atccgagttt tcctctaagt
     6601 aagtcagtga ttaattcttt tgataaagtt gcaggaagta aatcttcatc tttcagatca
     6661 ggattaaaat gttttgaata agctggcata tggatatgac ctgccataat tgaaggtaat
     6721 ccagcttcta ttaagcctga gtatactttt ccaaaagaat tatcccattc ttccgtacct
     6781 aaactattaa tactaaaaga tagatgctga tctcgttcgt caataccgtc accagggaaa
     6841 tgtttagctg caggcaaaat tccactctcc tgaatacctt tcatataagc taaactaagt
     6901 tctaaaactt tatcagggtt ttgtccaaaa gatcgactag aaatgatagg atttctccaa
     6961 tttctattaa tatctacaat aggagcaaaa ctccagttac atccaatagc cgatgcttca
     7021 atcccagaaa ctctccctaa ttcataagca tatttcgcat catttgttgc accaattttt
     7081 acttctacac caacttcagt accatctgta caagctccgt taccacctgc ttccgtatta
     7141 gcagcaatta atagaggaat tttactttct gtttgtaaga tatagttttg atcatatacc
     7201 tcatcagcag ttcctggatt atatcgtaca gctccaatat ggtactgatt gaccatatta
     7261 ctcaagtaat ttttatcacg actagatccc atattaacaa acaattgacc tattttttct
     7321 tccaaagtca tagaatcaat cgtctcttca atccaagaaa tagcatcttc atctaaatta
     7381 tatggttttt ttcgtaaatc tacttttata gtcattttct ttctcctcta cttattagta
     7441 agatttttcc aaaaagtatc tatatatttt tgttcaatat ctacataatc tcccgataaa
     7501 catttaaata aaacatcagt tcttaagttt tcccatgatt ctttttcttt attgaccaaa
     7561 ataggataaa agaaaacttt atttttattt gcagcttcta gatcaccagg agaatcacca
     7621 atcattaata tcttatccaa atcacaacca ttttcaatta cacttcgaat aatatcttct
     7681 ttttttcctt tatcttgaca acacagttca tcaactaatg ataataattc atgtctttcc
     7741 cattcttctt gaacagcttc cttattagct gagcttacaa taattatctt cccatatttt
     7801 ttcagagctt ttatagtatc tctagcactt aaaaagggtt tatctaatcc ttttgcttga
     7861 ctaatctgtt gattgacttc ttccgaccat tttaaagctt ttaataaatc ctctgactga
     7921 gaatattcta tttccctctt caaagatgga ttagacaatt cttttgttag agatacccag
     7981 tgctttaatc gattaatcga tgttacatca tttttttcta atgttttaac taaacctaaa
     8041 aatctgttta ttccacgagt ctctgaatat aaattaatat tattccaatc ctgtaggaat
     8101 ttttctctat gatgaacatc aaaaatctct gcagcaattg gtccgaaaaa gagattgtgt
     8161 ttataagtca tcgtatccat aacacagcca tctgaatcaa tacaaaatat ccaattattc
     8221 atatttctct cctatttatg tttttgtttt aaaagctcgc aattttctaa gactttatct
     8281 ttagataatg gataaaggaa aaataaaatt aatcctacaa tcagaaaaca aattgatgga
     8341 attaatgttg aagcgttata taacttttct aaaacatctc ccgtttgtac atttgctaaa
     8401 gagtcatagc ctataataga aagagtccaa cctccgacgc ctccagctag agcttgacct
     8461 atttttctag caaaagaata taccgcatat acggtcccat cttctctttg atcagacttt
     8521 acttcttgat catcaataac atcagtaata tttgcccaaa taacagtatt aaacacaccc
     8581 aaacccatat agccaaccga actaagaatt aagaatacat acatattact agcttttatc
     8641 aaaaataaga tcaaatatac tattgctgaa aagaacattc ctactgatgc cagttctttt
     8701 tttccatatt ttttacttaa aaacaaagtt aaaggcgaaa caactattaa aaccaaaata
     8761 ggattgataa aattcattaa aactattccc tgtgcatcat tatagtaatc aggaaataca
     8821 taattattca tactcataat taataattga gcaaggagta agaaaatagc cgcaccaatt
     8881 atagaaagta atgccctatt tttaactaac ccttttaaag attttaacaa tgaaactttg
     8941 tattgagatt ggtcaattct tactcgttca gtagttagtt tataacatat taaataacaa
     9001 ataagtgcac atatcgaaaa tattcccgca acaattgtaa aagttgatcc accacgaact
     9061 atttgagcgc ctgaatcatc tcttgtataa ataaataatg gtgttaatac accaatgacc
     9121 aaacttgcta aagtagctcc aacatttcgg aatgtcgata gcattgttct ttcttctgta
     9181 atagaagtaa tagctgatgc cattgatcca taaggaatat ttatagatgt gtaaaaaata
     9241 ctcccccata atatatacgt aacatacatg tatactacct taacgctcat agaagctgaa
     9301 atcatagaag tttgatacat taaaaaactt gctaaagcga ctggaccact cattcttaaa
     9361 atccacggtt taaacttacc ctgcttagtt gctttcgatc tatcaacaat acgccccata
     9421 gttacatcag taactgcatc gataaatctt gctactaaaa ataatgttcc aacggcagct
     9481 ccgcttatcc ccaatacttt tgtataaaag atcattaaaa aagaactagc aaaaatgaaa
     9541 gtaaaatcgt ttccaaaatc tccaaacata tatcctattt tgtctcttat accaaatttt
     9601 ctttccatac aattctctcc cttctgttgt taagcgtttt cattctgatg aaagtacgta
     9661 ctatactctg aagcgtaaag agtcagtatt tattttttac atttcagagt attatttgtt
     9721 ttttctccta ataattcttt atctcataaa acttatctat atatttacta gctactcgac
     9781 ttacttcttc aaaatcacct ttttcaacag aagccaataa attcccacct acaccaactg
     9841 caacaactcc tacttcaaac caatcttcta agttctctat acttactccg ccagtaggca
     9901 ttatatttac gtgtggtaat ggagcttgat aggcttttac aatggatgga ccaaaagcag
     9961 aacctgggaa tagtttaatg atatctacgc cagcagtaag tgcctccttt atctcagtaa
    10021 ttgtcataca acctggtaaa taaggaattt gatataaatt acaaatctca gctgtttgtc
    10081 gatcaaaaga tggactaacg atatattctg ccccagccat aattgcgata cgagcagtaa
    10141 acgcatctaa aaccgtaccg gctccgatta ttacatcttt ttgatcagca tattttttag
    10201 caatttcttt gattatttct tcagcattag gaactgtaaa agttagttca atccctttaa
    10261 ttccacccgc aataattgaa tttattgctt taatggcctc atccttattt ttcccacgta
    10321 caaccgcaat gactccagcc gcttctaact tacttaaaat ttctactttt ttcatatcta
    10381 tctccttcct ttatggatac atactttgtc tagctgtact aacttacaaa gaataaattt
    10441 aagcttttat ttcaagtatt attttctact tccgatttca aaaaaattaa aataattata
    10501 cgcattacga taacaaatat tctccactat ctgactaaga tacatttcat catctggaat
    10561 tcggcctgct ttaacccact cgcttagtaa ttgacataat actcgacgaa aatactcatg
    10621 gcgaggatag cttagaaaac ttcgagaatc agtcaacata cctgtaaaat tcgacaacaa
    10681 actttgttgt gccatcgtag tcaactgttg acgcattcct tcagctgtat cattgaacca
    10741 ccaagcacat cccaattgga ttttttgaat cataccccct tggaagcttt gcattgctgt
    10801 tgctagtgga agccaatcag ttggatttaa tgaatataaa attgtttttg gtaagcaccc
    10861 actcttttca gcggtatcga acaatgctac aacattttgt gtcaaactag cttgatcccc
    10921 catcgaatca ccaccgacat ctactccaat ttgttccttt aatatacttg aattatttct
    10981 taaagcattt aaatgcattt gcatcgtcca accatatctt gtatactcag acatcaaatg
    11041 taattgaata cctgtaacaa attgtgcaat ttctgataaa tggaaatccg tttttcctgc
    11101 taaagctttt attaacagat tgtcgagtat tttttcatct gctatttcat aaaaataagt
    11161 attcaaaccg tgatctgcta atcgacagcc aatttgatga aaatgatcca ctcgttggct
    11221 caatgcttgc ttcaacccat taaagtcttt gattggtata gccgctgttt gactaagttt
    11281 taaaatatag ttcgaaaagc ctgatgattt gatactccag accttatctg gacggaaagt
    11341 aggtaatacc ttgaaagaat tatcctgttt agaaagctca gtatgatacc acaagtcatc
    11401 tgtaggatca tccgttgtac agatggcttt cacatccatc atctccaaca attctttcgg
    11461 gcgataggaa tccgtttgaa ttttttcgtt agcacgtcgc caaatttctg gtgcattctt
    11521 ctcagaaatt gtcaaatcaa tatcaaagta acgttgtaat tccaaatgag accattcaaa
    11581 aataggatta cctggcgcct tctccactgt ttttacaaaa gctaaaaatt tttcataatc
    11641 atcacctgga ccactgatca actcttcttc tataccatta gctcgcatca atcgccattt
    11701 ataatgatct ccagctcctt tatcatttaa ccatacctga gtcaaattct tgtattgctt
    11761 attttctagc aaatatgctg ggtctaaatg acaatgatag tcgataattg gttggtgttt
    11821 tgcaaattta tgaaaaagtc ttttagctat ttcattctct aataaaaagt tcttatctaa
    11881 aaacatattt aaacactcct ttccttccgt tagtttttag aagagaaaat ttttcctcta
    11941 aataaactcc cttatataat tatttactcg cccccttttc aagcgcttcc caaataccat
    12001 ttaaataaac tgcacctaga gctcggtcat ataatccata accaggtcta ccggtttctc
    12061 cccaaatcat ccgaccatga tctggacgaa tatagccatt aaatccatta tcgtacattg
    12121 tttttaatat cttatacata tctagagaac catattctga tttatgcggc gcttcgtaaa
    12181 aatcgagtcc attgtcactt aaatatttga tattacgaac atgtgcaaaa ggaatccgat
    12241 cccgttgaca aaattcagat agaatttcat agacatcatt atctggtcgt tctgcaatac
    12301 ttccagtaca taatgtaata ccattagaag gagaatccac tacattacac aaccaatcta
    12361 aatcgtcacg atttttaaca atacgaggta atccgaaaat ggaatatggt ggatcatctg
    12421 ggtgaactgc cattttaatc ccaacttctt cacatgtcgg gataattgct ttgagaaaat
    12481 atgcaaagtt ctctcgtaat ttctcttcat caacttcttt ataggcttct aataattgct
    12541 taatttgtga taaccgatga ggttcccaac ccggcaattc aaaattatta gtagaatttt
    12601 ctacttctct aataatttcc tccggatcag tagggatatt ttttgaaata taggctaacg
    12661 tagaagaccc atcatctaaa cgataatcca aatccgattt tacccaatca aatactggca
    12721 taaaattata acagataacc tcaatcccaa attctgccaa attgcgaatc gtctgtttat
    12781 aattctcaat gtattgatct cgtgttggta aaccaatttt gatatcatca tgaacattaa
    12841 cactctcaat aactttcaag gtaagtccat tggcttcgac ttcatctttt aaagatttaa
    12901 ttcgttctct cggccaaacc tctccggctg gtatatccat taatgttcca acaattcctt
    12961 tcattgctgg gatctgacga atttcttgta gtgagatttt ttcttcattt gccccatacc
    13021 atctaaaagt catttccata gttactttcc tccaacttct gttatatatt tattgattgt
    13081 tttacgaact gcttgaggac ctactagcat ttcgcaaaag attttttcag ttttctttcc
    13141 taccccaact tgatataaat ctaaaccaaa gatttcttta ttttctaaaa tttcctgtac
    13201 cgcacaatga atctttgaag gatcttgttc acctaatttc aatactgata atttatcctg
    13261 caactctacc aataacggat caggacttgg cacaaaattt tccccttgat catcgactgc
    13321 cagtaaataa cgtaaccaag cagcaatagc gataggaata aatgttagat tttctgcatt
    13381 tccgtctttt tcgacatact ttttaattgt ttcaccatag cgaatcgcta ctttttgaga
    13441 agtatctgtt gcaattcgtt gtggtgtatc tggaatatag ggattaggca aacgtttatt
    13501 aattacttca tcaataaatt gttttggatc aataatgcct ggattttcaa ctactggtaa
    13561 accttctaaa taacctattc ctttgattaa accaaccaaa tcatcatcct gcatctctgc
    13621 tgaaattgat tgatatccta gcagacaacc tgttactgcc aaagcagtat gaagtggatt
    13681 caagcttgtc gtaaccttca tgatgtctgc tttatcaacc gtctctctat ctgtcataat
    13741 cacaccagcc ttttccaatt taggccggcc atttggaaaa ctatcttcaa taactaaata
    13801 atgaactacc tcagtattag tgaaagcagc aatattggta tgtttttttg tgtgaatgat
    13861 atctaaatcc tcgagcccca tcatcaatag atcttccttt acattctctg aaggatttgg
    13921 cgtaattcga tcaatcatac tccaaggaaa agtcactttt tctttatcct ttaaataagc
    13981 aataaatttt tcagaaacat atccttcttt ttgccaagct tctgcaatcg taaaaatact
    14041 atcttgaaaa cgttgaccat tctgtgagaa attatcagta gaaaccatcg caatcggcaa
    14101 ctctccagca ttaaatctgc tatataacaa ggatgttaca atactcatcg tatgttgagg
    14161 attgctaggt ccagatttga tatcagcttt gactaccgaa aagaattgcc ctttagaatc
    14221 ttttaaactg taaccttttt cagtaatagt aaacgttgta aactgtaatt taggatcttc
    14281 aaaatattta accactcttt gatagtccgc tatattcttc ggattgcaat ataaactatc
    14341 agccgttact gccaaaagtc tttttttgag ttcaccatct ccactcataa caatttccaa
    14401 aatgtcattg ttatagtcat gataagcttt ttccactact tcttcatcaa atgtttcaca
    14461 cacaactact cctgtttcta attcattttg atctgctaag cattgagcaa tttctgcatg
    14521 aaatcctcga taaagatttc ctccaccaaa atgaagccat actggatgtt gctggccttc
    14581 ttgcttaact tctttgacat caaaacacgg cagtagaatc tgcatttcat tgaattcttc
    14641 gatagaattt tgccaatttt taatcgaaac cataattaac ctcctcaaac tgatatgtta
    14701 gttttgatac attttatatt ttaaaaccca ttgtaaccgt tgtcaatata aaaagggaat
    14761 aaacttgctt ttttctacca tatcagaatg attgtatttt ttattcagaa aaataaaata
    14821 ctccttcttt ttggactgat tttatcgaaa cttatttttt ctttttttca tgtattcttt
    14881 tatttttata actagtgtat tacttcaaaa tttgatatta tatggcatga acagaattaa
    14941 aatatcagtt aaaataaaag ttaaggagca ttgtgtatga caattaaaac tagtctccaa
    15001 aatcaagctt accaatctat tcgccgacaa attatctatg ctgacttaga acctggaaaa
    15061 aaagtatcag aaaaaaaatt agaagaaaca ctttctattg gtcgtacacc aatacgtgaa
    15121 gcactgattc aactccgaca acaaggtctt gttgatacaa ttcctcaaag cggaaattat
    15181 atctcattaa ttgatttaga ttcggccaaa aatgctcgat ttgtcagaga acatttggaa
    15241 cgacaaatta tgttagagtg ttgtgccaaa atgaataacc aaaaaaaacg gattttagaa
    15301 actataattt cagaacaaga aaaagctgtt agtcaaaaaa atgctcgtag tttttttcat
    15361 aatgataatt tattccataa agcttgtttt gaaattgcag agcgagaaga agtatggcaa
    15421 tggttagaaa ataacaatac acacttagaa cgatttcgat ggctacgagt aaaaacggaa
    15481 ggattaaagt gggaaaaaat tatggaacaa cattatcaac tatttgaggc attaacaaaa
    15541 caagatccag aagaagctaa ctttctaaca tcgttgcatc ttcatttaat gcttaatgag
    15601 caaaatattg ttttagctac tcatccaaaa tatttcaaaa atatataact tttaactctt
    15661 tttaaattaa atggttgttc tgatcagaaa aatatcgctt gttttcttat tatgtaatat
    15721 atttcataaa ctattctgca taacaactat tgtttgtact ttttacattg gataactaat
    15781 tatgactgct gataactttt gatattaaac tagtatctcc aatacaaata aaaaatagat
    15841 atcttgttca tcaaaattag ttcgtggata cttaccttca tttacatcat tcagcggttt
    15901 cccattttct tttattctat tatttcattt tctaatagac ttggcttcat ttcgcaatac
    15961 tttttttcaa taggcatcaa attggtgttg tttagatatt tagttgtagt tttgtgacat
    16021 gataagtatg ctcctttttc tcttttccac taatacaacg atcaaagggt gcttttttca
    16081 aaaaactaga aaaatcaaaa taagattcgt attttgattc tatatatcct gtttcaacta
    16141 catcttatat ttcacaatag aataaatagc cttttgcata gctgcttaac ttataagaaa
    16201 ttgcaattta cttcttcaaa gtgaaaacga atatgagtaa aataaaatta ttcttcttac
    16261 agataattaa aaatagcgcg taacaaaaat cggcattcaa tcacataatt aggattgatg
    16321 ccgattactt atattctacg tatagtttta gtattcttat tttttatcac cagtaaccaa
    16381 ttgagaacag ccctaaagca gaatagtctt ttatctcaaa acgcttaatt tcaggcttag
    16441 gaatatgaat aatcttttga gtatattctt tctcttttaa tcttactgaa gaaataccac
    16501 tgcctatctt ttttacaaat atttcatttg gtgtacagac taataaaaca atatttgtaa
    16561 tcaatccttg cactaaagaa ttaaaaggaa gactatttaa aacagggtgt gcataactat
    16621 aacatgtgaa gtagttattt tgaactttaa cttttaaaaa ctttaaaaat aatcttattt
    16681 gttcttctaa acaatcatct atactcatat aatcactcca ctaattaatc tccccaaaaa
    16741 gacacagcat taagagatat accaacacaa cagtgcaaat aactctacat cttccttcgc
    16801 aaccttattt caataaacca taaaaattat tttttaatag aaactgaaaa ttaaaactag
    16861 aaaaagtagt tttaccgaat gtaagagcat catcaccatc aatatagaaa tacattcttt
    16921 tccagttaca tttaattttt aaacaaaatt ctccccaaaa aggaactttt tctagtgaaa
    16981 acttggtaat ctctttgtaa ttaattcttg ttaaagaata attaaacact tcatttttac
    17041 ttgttatttt ttcattgact ataactagtt catctggtaa aaaaattaac caacaaacat
    17101 cgacaaacag taaatgatat aatccatttc cacctccaag catattcaat actggtgaac
    17161 atgccttaga aacacgaata tagttatggt ttaaatagat attttcttta aacattgctt
    17221 gtttaaaagc catatgctct tgttctaaac ttttcataaa cttttactct aatgcacagc
    17281 tagcagcagc tgctgcaatt cctgctacaa tatttacctt agctaactct ttagctgcag
    17341 cttttcctaa ttgtttttct gcaattttta ataataaatc cgcagctttt tcaaaattaa
    17401 aagcttttaa tgcttcaata aaatctccct gcgtacctat agcccaagcc actcctcctc
    17461 caggaagaga attaatggct acacatccag catatcgttt ccaatcaact ttctccattc
    17521 taggaacaat aatatgttca taaaagactc ttgctgctct tccttgttcg ttatcttgac
    17581 tgattcgttc acgaatagca ccaaaatcct ttatatggta tacaccatgt tcgtctaaaa
    17641 aaccaactgt atcaaaataa aaagttaatt catctactaa tttattcttt atttctaaat
    17701 caactgtatt cactttttct gtggcataca cacttgttcc agtactaaca aaagtactta
    17761 aacctaataa gaaaacacct aaaacaccaa atattttaat tattcttttc ataatttctc
    17821 ctccataaaa aataagttac tttttaaata tcttgtttat gaattcattc cccaaaggcc
    17881 ttttaagatt gatacagcag tccgttcact tcttttagac ttgtcataca agtcttttaa
    17941 atgatcccat atcagactag tttgtctatc tagcttcaat ccattaaacg ctaatgaacg
    18001 gttcattttt tctattactt tagataaagc tacagaaatt tttatacctt cacaacgcgc
    18061 atcttggatt tcaataatag tatcatcaat tagtttttga atttcttgcc tatcaacata
    18121 ttcaatctta gaaagagaat cttttaaagc tactaatgat tcaacgattt cttttttctc
    18181 ttcagacatt ttcttcctcc ttctagtgac ccgtaaagcc atgtagagca gagtccattg
    18241 aaccagtaat tacactatct acaacgccat tccaatttac tctacatttt ccatttttca
    18301 gatttgtcgg tccatacgga tagccttttt gacattcaat gttcggatta taccagatag
    18361 gattatacca ttcagccgca gaagcagatt cagtcgatac aaacaatccc acaccaacaa
    18421 atccaataca catcacacta tagccaatta gttttttcat ctcgtatcca tctcctaaaa
    18481 aatagaatag ttcttatagt tattcataag acatattttt tccgtttttg ttttatcctt
    18541 tctgtcctat aacaactttt ttcaagtaaa gaatgacata gtttttctta aaaaaacagt
    18601 ctgttttttt ctatttcttc ggtgtataat aaatatgagt gttcattttt tattttaata
    18661 cgcactccgt acataataaa tcttgatcgc atcaatcttt tgagcttctt gatctacttt
    18721 caattgaagt aatacaaatt gagtaacctt attcattgtt tcttctccaa ataacaaata
    18781 ttgatccgga ttctctatat cttgtgtcac ctggtaaagt ttcccagttg ttttcatttg
    18841 tacatgcggg tctacatcaa tactattgtc tttaatacaa cgatctgtca tatagtccct
    18901 cacagcttga ttgcgtttat aaacatctgt gaaattactc cattttctag caaaatcttt
    18961 taagaaattt tttgtcattt catctatttg catttgttgc gctgtctcgt cttctaatga
    19021 accaatttga ctgttacttt cagtactttg aagagttcca cttgtttctt ttactgcttc
    19081 gattgtttct tctgtcgttc tcaattgtgt tttttgtttt tcagaagaaa accaatgaca
    19141 accagtaaga cctatcaaac ataaccaact aaatactaaa attatccctt ttttcacgtt
    19201 tctagtcact gcctttctta tttcacctta cgaaccagac tacgaatttt tgtttgattg
    19261 tacgtgcgtt gataccgagc cataatccgt ccttgctcgg cattctgttc cacactagag
    19321 aaatgttgtc cgccatatga aacatctgtt ataattccgg tgtgaccata gattccagga
    19381 gacaatgcac cacctgcttg ccaattcacc acatctcctg cttgtaaatc acttggtttt
    19441 gggttcatga ttacttgcca accataggtt gtccagttat aatcttcccc tattaacatc
    19501 gcaaacatgt gtccagaacc cattaactgt gggccaccta attgagatac ataccatgcc
    19561 gtaccaccat aacattcccc attatttacg gatcgtccaa tgatccgatc caaaaccttc
    19621 gcattgcctt tactttttcc tgcaataagc gaagtttttt ttgttggtag gctattccaa
    19681 tgcttgatcg caaaagtatc atattccgtt aagttatagg acgttatgat actcattgct
    19741 cctcgataat acggactccc ttcggtaata cctgctgccg catagcctcc acgacctaga
    19801 atcaataaac aacttccagg atctttattg cccacacatt gattaaagtt gctttggctc
    19861 gccaccataa agccataata gtcataacaa gcttttaagt tcggaaactt catatagaaa
    19921 ccaccttcag aaccaccaat tccacgtgca gaaccttgtg ggtagggaca accaggaaac
    19981 caggtaatcc caaaaaagtt cgtatcgttt cttccagatt gtgactgtcc ataagctgat
    20041 tcatagccta attgagaaag aatcacactc ggtaataact gatactttac agctgcacca
    20101 actgctgctt gcgcatgttc atctgtgatt ggaccacgtc ctttaatctc tgaaaaaatc
    20161 ggtaatcctt cggtatattc cccattaaaa gcgacagcta gacctgtagc ttctcctcca
    20221 tgctcagaaa gttctcctga aaaaaagaat ggcaatagaa aaaagggaag aataaagaaa
    20281 agaagacaac ctagacaccc tttcttcatt tcttcctcat cctttcttcg ataatggttt
    20341 ttggactgtt cgtccttttg gtaaagtaaa atcagttcct ggttttgcgt ccaaaatcgg
    20401 cagtgtttta ggatcctttt ctattttttc cgattgctct gttggcttat ctaaagaaga
    20461 aaatgcaggt tgtaacgatt ttggtgcgga aatcgacggt ttactttcag acgaacgttg
    20521 ccccggttgt tgcacagaac gatttcctga tagagtggct accgacgaat taggaacaga
    20581 gtattggttc aataactgct gcattgctgg ataactccca tttttcgcct gatttttcac
    20641 ttggcgaatc tgttgtgaaa gagaaccagc agctgttaat tgtggcacgg gtacttttcc
    20701 agaaggcaac ggaatcgatt gaccaacaaa agcgatacct ttatttaaca atggttttct
    20761 ttgattattc ccttgttgct tactcaattg tgccaatgat tgtacctgtt gttttggtct
    20821 tactgaattc atggacgaat ttggaatcaa accatttgaa agaccagaat tccactctgt
    20881 tttcgatttg gtagaagaca tttcaggctc taccccatga taacgaacat gacgaccact
    20941 ataaggcaag gcttgatttg aacgcccacc tagttcaaag ggattaacca cttgcctccc
    21001 ttttaccgat tcttgtggtg tacgtttttg ttgaaacttt tgaaatccat gtatcgctgc
    21061 agaagcgagt ggattcgttg ctcgatacac attccctgct aatcctgcac ctttgattgc
    21121 caaattttgt ccagcagttg atagttgacc aggcagttgt ttcatttgag acaaagaatg
    21181 acttgctatg tttttcgtgt tgtttatagt ttgatctgca gctcctaacc ctagtttctt
    21241 taataaatct ttccgtttta caatgagtaa aattgatagg agtgctttga caaacatatt
    21301 tcctaaaaaa ccaaaaacag tattcattgg aattaaatcg tctactatgt tatagatcaa
    21361 aaatgccacc aaaataatca cactgtaaaa agatttttga aacatcaagc ccaaaaagga
    21421 ctttaaggta ttcatgagca tataatcaaa tactggaaca aaagaagcga gtaatgaaaa
    21481 aggaatcaca agtaataaac acaacaccaa catttgaaag ataaaacgaa tcatgccaat
    21541 cactacaagt ggtaatccaa tacttagatt aagcaatggc accatagaac caacgactgc
    21601 tttataaaca gctttagttg gttgaatata gacacgataa gccttctttt tccctctatc
    21661 ttctcctgca gcagtggtca cttttgtctc aatatcagat aattcttcac ttgacgcttc
    21721 cttggctaga aattcttgtg gttcaatctc tgcttgatac aattcttcta aatttgttgt
    21781 cccataattt aacaatatat acggatcaac aacagccgct ttataataaa gttggcgcac
    21841 tttttgaatg gcttcctttt gtgtcgttgg cactaaaaca ccattgacat cttttgtcgc
    21901 caattcatct agactatttg tagcagaaaa aataaagcct tctacctcca cggacaaatc
    21961 atttaaccct ttggtaaaag cttctccttt actaggtacg ttactaccat agccaaacca
    22021 aaccattgaa aaaatgacaa cgaagagaaa tcgaataaac accatttttg cgtaatgttt
    22081 ccctctaaat atacgaagag taaatagata taacacatac aagacgacaa tccccgcacc
    22141 aataggatcg tatatttttg aataaatagt atccgaaaaa gtgaaaaact ggtgaattaa
    22201 ctcgttcatt gcagctcctt catagagctt ctcaatgaca aaatcaaggc cttgccaaat
    22261 caatttactt aaactaaaga acatattcgt catcattttt agaaaatctg tgccatttgc
    22321 cccaaataac attttgccta atgaaaattc actatcagat aaataagaag aaaaggtatc
    22381 aatatgaaat ttcccaatct catagatcga ttgatccacc tgcttttctg ccgcatacac
    22441 caatccacca acaaaaagca gtccgaatcc aatcgttaaa aaaaacaaaa cgcaccattt
    22501 cttttcctta tgctttatat aagccattgt ttcacctcat ttctattgca tgattaacgt
    22561 atcctgttct tctacttgag agtgacttgt tttttccgtt gtttgtaatg cagcggtcat
    22621 ttcttcaaac aaactgtgta cattgagttt tcctacacgt ccatagggat ctaacatcca
    22681 acactgtcct ttaatcatgt ggctcatttc agctaagttc gcttcattta cttccaaacg
    22741 taaatgattc aaaatctttt ctcgctcact gtcttcatca aaagcaaaga cgacaccaaa
    22801 attccctttt tctttatctg aacctaagtc accaataaat tgtgtatcta acactaattg
    22861 attcatctgg gaacgcccca cacgtgccat tgctgcaata atactacgtc ctgcgttcga
    22921 attattaaat acccatgctt ctgtaaaata aatcgctgtt ttcttactac tatctcgttt
    22981 tccaaacatt tcacaaaaac gacctaaact aatcatcaaa cacaaagact ttcgatccgc
    23041 atctgtatat agttctggtc ggacattgtc atttggtaat ttcaaatctt ggatctctaa
    23101 aatcgttgtt ttggcattaa agtctaatcc cgggttttct ccataagaaa atcctaaacg
    23161 taaaatcgaa tcttctaccg tcaagcgtaa aaactcacca tattctcgaa cctctttttg
    23221 ttccatttgt tctaaatagt cgaccacatg catcaagcca acttgttgtc cggcttcttt
    23281 ttgaactaaa acttcttgga ttccctttaa taccgcccct tttaaaaggt gattggtacc
    23341 taacggactt aactcatcaa tcatatcctg ggctacttgt ttcgcatcta ctcgggataa
    23401 acaaacaatt ggatctaata caccataatt acggggattt gtagcatcta acgtgacata
    23461 actcattttt tgcaaatgtt ctacaaacaa agggtaatgt ttctgataat acgggtcttg
    23521 aatgagtttc gtaaaccatt tgcgcttttc tcctttggga tccacaaata aactttgtac
    23581 attcataaac gaactataca aaaagagcaa gccaactaaa aaggtcttcc ctttaccggt
    23641 ttttccagtt actgctacat gaggcgcatc aaacaacgca cctttgattc cttccgcaat
    23701 ggctagaaga ttcaaaaaga caaaacgatt tgacgcataa attaattctt ctaatggtgt
    23761 tttttctcct cgagaaccac catcccctaa tgtatcttgc cgaccaatat accagccgga
    23821 ttccatacct aattctgata ctgctgaaaa caaccattcg ccaactgctt ctacagttgt
    23881 tcggtgcttc caatgtaact gccgtcccaa tggttgccct aataaacatt tatagaacaa
    23941 ttctcgttga tcattttttg cacggtggat atggataatc gtatgaagtt gttgaataac
    24001 cgttgcacta ttttgacgaa cttcttcaac cgtttgaccg tatacaataa aacatgcgat
    24061 ccaatcgacg acaggttgcc cattatctac tcgttgcttt aaatgtttta ctaatcctcg
    24121 aacagttaat aagcgttcac taggttcttc atcattttga accaattcct tatgctctgt
    24181 tttgaaccgt tccgatagcc aattcagttt taaaccaata cctccctgtc ctttcaagcg
    24241 tggatagtga attttcattc gcaattctgc tgggaaagaa agatcctgag caaattgaaa
    24301 tagatcacaa tttctcatat tttcaggtgt ttccccaata ggcaacaatg ctaaataact
    24361 actccctaac tcatcttcta attgaagaag gcctttatgt tccttcggta tacgtacata
    24421 cgttccttga ttgtctttca gtacttccca attattttgt tcttctactt tgtgagccat
    24481 tcctcgaata tattgcagac gattgagata caacagctct ttttttacta agggacgaat
    24541 agaaaagcta taaagtaatt gtgtcacttc ttttacataa ggatcacttt cagaaaacaa
    24601 agtttccaaa tcatctactt ctaatccaaa taagcgtgct aaacttcctg ctaaatctaa
    24661 ccagattaga tttattacat catgaaaact ctccaccgtt gctttttctt tgactttgat
    24721 tcctaaaata aatgaaggac gatagacttg accttctcgt tccaacaatg tcactgtttc
    24781 ttttgcataa tacgcaccaa ttgcttgact atcgggagaa aatccctttc ctaatgtgtc
    24841 aaacttcgtc cgtaaattca ttgttcgtgg atacatcacc aactccacat cttcataatc
    24901 tgctaaaagc aacagtaaac gagccatcat ttcttttatt tcctgtgtct tttttggtgt
    24961 gttttttgaa attgttcgtg gaaaaacatg atagtaggcc cagatacaat cctctccatt
    25021 taacaaacaa tttttcttga atgcttttac tggttctttt acaagcacca atgaatttca
    25081 cctcccaata aaaaaggaac aaccagttga ttgtcccttt ttctaatcct ctaaataaac
    25141 atacttattc acaaaaagta attcttccaa tgcattgttt gataccttgt cccagttata
    25201 atacacacaa tcaccattca tcatacgaat catataacaa aaccaatccc ataaataaaa
    25261 atgcactttt tttccatcag gttttagttt tgccagtgct aacacacata aataggggag
    25321 tcctatataa aaaacaactc ctgctggtgg aaaaaaagaa atgacccaac caataaatga
    25381 acgtaaaaat aaatattcaa agattacgac caacaaaaaa gttgctgcat tgactaatgc
    25441 aactggaaat ggaagacgcc aattgcttgt aatctgttgt acgcgataag gttccgcata
    25501 aacaatcgaa taatcataag gttcccaatc cacttcacta tcctcctaat ccataaataa
    25561 tttttcaatg attttaccaa acgcatcaaa tacacgtgtt ggatcattta agaagaaata
    25621 aactgcggca cctgctgcga tagatattaa tgcatttcct acttttgatt tcataaaatt
    25681 tcgcaatccc agataaacaa ccaccattat taaaaaatag ccaccttgcg ttaatataaa
    25741 atctacaatt cccttcagtg tcatttccgt tcttctcctt tcctatccaa ccaattatgt
    25801 gttaattttt caacataata ctgatttgtt tttttcgtaa tgacaatcgt catttgttct
    25861 ttttgtaaaa gtgacgtatc accatctcga aagacgaccg ttgcttttac aataaaaggt
    25921 tttttcgttt ctttataacg caatactttc atctctactt gatcaacttt agctgtttga
    25981 ttgagtcctt caggttcttt catcatgtat gacatatctt ttgcattgtt tttcgcatac
    26041 ttatctaaga aatcttccac aaatccttca acatctttcg cttccgacgc atcaaccgtt
    26101 tcgtataatg tgtcatcata agtaatcatt cgttgttttt ctgtattctt tggtagtgcc
    26161 gtaaaataag gataagcaat aatacgacag cccttgtttg aaatagaaaa gggaagattg
    26221 agtacttgtg tgattgtcac acttgtttct ttcttactct ctggattcat cgagcgaata
    26281 tcataagtta ctttataact agcagttgga atggtttcaa tttcttttaa tccaataaac
    26341 gaagcagcag ttaattttcg aacacctgaa acacttcctg gttcttgaat aaagttttgt
    26401 gcataaaact ctttttttaa tgtttcttga cgttgttgtt cttgttcatg attatcgaat
    26461 gtattcatat acaaagcaac aaaacgattc ataaaggatt caatttcagg tgtgtacgtt
    26521 aattctgacc gactttgtac ttctttcttt tgtaattgtt ggatttcatc tttcaaaaac
    26581 gacacttgaa ccttcgtttt catggattga aaaaatgcca agccccctga aaaacaaaga
    26641 aataaaacca aacaccaaat ccatttcact gctttttttg aatggatttt cttttgcttc
    26701 ggtactttct ctgtataaac tttttctttc cgccgtagtt gtcgtttttt cataagctac
    26761 tccttctagt atgtttttac tagtacgtac gattgacaac gataagcttg tttttctgaa
    26821 aaatagtcca ttcaattacc ctcattttct attccttttc tctttctttt atatccaaca
    26881 aatccagcaa tacttgtcaa cactcctcct agaacagaaa gtgcaacatg tatttcttca
    26941 ccagtctttg gtaagacttt tgtttttcca tctgctgttt tgatttcaat attgccactt
    27001 ggaagtttct ttacaggaat cgacaaatcc tttaccaaat tcccttcact atcttggatt
    27061 aatggaatac catcttttac accaacaatt gtttgatcac ctgctacttt taatggggtg
    27121 gttggtgttg gaatatgggt caattcctct acattactag tgacaatcgg tacactcatt
    27181 ccttgagaag tattcgtcgt aatttcaccg cttggggtta ccgatactgt gacttctttt
    27241 gctggaacaa taggtttatt ttcttttgga attgcttctg atttttcaac aggttgtttc
    27301 ggttcttctt tttgttcttc actggtagac gacatcgttg gctgttccgt acttgacgaa
    27361 tcagtattct tttcagaaga actggttgtt cctgattgtt ccggagttgt gactatactt
    27421 gaatccgttg ttgttgaact atgcacacct tcttcttcga tcgaatcagt cggtaaagtt
    27481 gattcaggaa actctggttc tggtgtcact ggctcttttt caggtttctc tgactgcaat
    27541 tgttcaggtt ctgctggttt ttccgttgtt cctccattta gctctgtctc aacatctggt
    27601 aatccttccc ctggcaatgt ttctacaatt tctgacttag gtgtttctac agtttcatct
    27661 gcataaacca atgaactccc taattgaaac gaaaataatg aaattcctag tgttgttacg
    27721 actgctaatg ttgttttttt catgattatt cctccaattt tttatgcaat tcgtgttttg
    27781 ttcatagacg ccgcactaat attatctgaa cgataaaaga actcccgtcc gttttcttct
    27841 aacccaacat atggattatt tttgaataat tgaatcaata gttcactggt gttgtatttt
    27901 ggatagtttg caaaaaaata atactgtgct tgtcgcccat ccgaaaattc aacaagtaat
    27961 tcataacgat accgcttcaa tccttttcgt tgttttaaag gatctctata ccaacttgtc
    28021 catcgttcca ttcgtggata gagatagaca cgatacacat agaacaatgc cataccacat
    28081 accaccaaaa ataataatcg ccacataaaa attccccctt ttcttctacc tttcttgaat
    28141 catcgaacat tcataccctc tatagagatt tgaaaaatcc atcatcaatt gttcatataa
    28201 acgttgttgc aaatagcgat tgtttcgaat acataattct tcatagccat caatcacttg
    28261 atcttctttt tcatagcatc ttgtagctct atgacgctca gcttgcaaga cataaccaaa
    28321 ctctgcacca tatcgttcta ctgttaataa ctgttgacta cgcaataatg caatataaca
    28381 atcacaaaaa tgttcaaccg acatttgatt tttctcacgt ttgtgaaata ggtattcttt
    28441 agaaagcaca ttattcgtta aacaatctga taaatagcga taatctggcg gtcggttatt
    28501 ttcatctgtg aatttttccc ataataaact gatttttatt cgttcagcgg ctagatagtc
    28561 ttgttcgcgt ggataaaatt catcaatcgc acaaagtttt ttatcacctg aataaacaaa
    28621 tccatataat gcgaaacgaa ctcttccttt tcaattggct ctcctaaaaa ttccagtgac
    28681 ataccatctt ctccttccta aaaaaaataa aaaagcagaa accgatttgg cttctacttt
    28741 tctttccttt tatagctctt ttttacggaa gaatccgcaa atgacatttt ttcaaaaaat
    28801 caatcggcac aagttcacga aaacttggag caattttgga tagaatcact tccccatctt
    28861 gtaaaataca atcataaaaa tcatcagtta cttgatactt acgcttctta caataattga
    28921 taaaatagta gcgatcattt tctatttcca ttcgttgttc tactaagcgc atacgaacat
    28981 catcatagaa ataagccaca aatcgccctt caagttcatg tttttcaatg ggatactctt
    29041 ctggtaacaa tctatttttt cgtcgtttat acattgctgg ataccttaga agaagttcat
    29101 ctaaacgtct gtcagtatat ggtaactgac gaatcaacga ttctaatcgt tctttataca
    29161 gatagaataa ttggcgcaag caatagtgta ccgcctctgg attttctaat actgttggat
    29221 cacgtgacca atacgcacca acataaatca taattttttt catttagaca atcacaccag
    29281 caatactaat gaccgatcca caataggtag aacaagtggc atagcgacca atttcctcta
    29341 attctatctc aatctcttct aaagaaagat atgtctgttc ttctgttggc tggcgactca
    29401 tttcccaagt gacagtcacc aatgaaattt cttccataag aggtttttcg ctgctaagtg
    29461 ctgccacaca gttttcatat atcttcattt tatcgcagcc ttttttaacc gctaaaatcg
    29521 caggtattgg caatgaaaat cgataaaagc gaatgaattc tagccttcct ttccttcggc
    29581 taaattccaa ctcttcgagt tcttgttcgt atcccttacg aacttctaat aagcgtgcaa
    29641 tttcttgcca gttctctttt tcctgataac gtccagcttt taccgcttgt tcaatataag
    29701 gaactcgaaa acgaaaataa gacaaatcaa ccatcttttc atttaatgct tcgattgcag
    29761 cctttaaatc caacaggcgc agccattctg ttgtcgtata tgcattcatg caattttccc
    29821 tcctgacgtt cccatccatt ctagatagtt ttgttgctcg tcatttagtt cggcattatc
    29881 aatcccttct tgtacaaagt ctcttcctaa aatacgatct gcttcttgta acaactttaa
    29941 tgtcggagct acttgtttca aaaaccagcg ttctgaacga tctaatgaga atttttctgg
    30001 ctttactgta aaatccaatt cttccatcga acgaaataat tttgcccatc gtttatcaac
    30061 aatccgtgca tcactttcca gtctatccca aacaataagt tttgcattaa ttaaaccaac
    30121 gccaatctct cctaaacgtt tcggtgaatc acctaaaata aatgcttcta ctgcttgtgt
    30181 tgctttctca ttggctaacc gtaactcata tcgattataa ataccatatt tcgttaatgc
    30241 ttctaattct gaaatttttt ctcggttcgc aatttcaaaa cgtttctcat aaaaattaaa
    30301 aaagagagga ctctttcgcg atccaaaata caaagataat ccttcacttc gaaaatagcc
    30361 atcatctaaa aaacaaccgc caatattctg gaatctctta aagtccattt ctaataaacc
    30421 tgctttttgt ttttctagta attcaaagag atcgaaatgt tcttccgttt ccaatcccca
    30481 aagttcatct aacgcaatat cgaatcggct acattgcaca cgtgtataac cagcttccaa
    30541 ctttccttga tttttccaaa tggaatatag ccatgttcgc caatctgttt gttgttcacg
    30601 catgacttcc tcatattccc ggcaaccttg tcctgaaaat tgcacaagta cattttctgt
    30661 tacagttcgt tttgaatgcc agaacaccca gatattccca cgaacagaaa gacagtcaaa
    30721 aagatacaag cccgttggac gtgtttcaaa ttctgtcaga tccattcgta atacacgttg
    30781 aatcactgtt ttgtagtctg tcccaaaaaa ggaaagacgc aaataatcaa tcattgctcg
    30841 aagatctatt ccgcttttca tatacaatcg aaagcgttcc ttgattcgtt gttcaaaatc
    30901 ctctgggatt tttcttttcc cttgttccat ctttctaatg taatcttttg agcagcccat
    30961 caattgcgca aatcttgctt gtgatagcgg ctttttatct ccacttatat tatgaattgc
    31021 acttaacttc tttctgtagc tttttagctc aatcggtgtc attttctcgc tccttttata
    31081 aaataacaaa atcgattttt tttaaccctt tagaaacacc gatatatcaa ctagtccccc
    31141 tcgttttttg ggaaaagtag tacaactgct gaccttagat aatcacttga tacaaaaggg
    31201 tttataaaac ttttttctat gtgttatgtt atttctgccc cccatattat atatcggggg
    31261 gctttacaca aagaggccgt gcgcaagcgc acgacctctt tgtgagctgc acacgctgct
    31321 agcgagtgcg cattataggc ccatgcttcg cagccttaat gcgcaccgcc aggcagagtg
    31381 cggctaccag actacgtcta gagccctccc gatagataat aactacaaaa ttaaatgatc
    31441 taattttgtt atttcactat atttttcagg agaaaaaacg cgataaattg acaaagttaa
    31501 atcctcttct aaatctactc gataatgata caatcgagtc aatcgttcta tatctttttt
    31561 cgttagcaat acttgattaa taacttttcc tgtaaaaaca cgttctttgc gcaaaaagcg
    31621 gtaatcagtt acttgttcaa tacgattcaa ccaatcataa aacgttctgg aagaaagaga
    31681 aggattaatc attcgtattg ctgtagctac tctataataa caactctctg ccatttaact
    31741 tcacctcctt agttgattac aaaatatgcg catcagaaaa acttgttcct tttggatctt
    31801 ttgctaaata catttggcgc tctagttgtt cttgtaacaa ctgattatca tctcccatcg
    31861 tttgatcttg actatcctct tttactgtaa aatcatagac aatcatttca gtaaatttct
    31921 caaattcttt gataaagtga taatctttgt aaacaaatgg cgcaaaaaac tctacaggta
    31981 catcaaatcc tggaaaagca tatccacgac caggttgatc tttgttgtaa aatggcttat
    32041 ttttaaaatc ttctccaaaa gtcattaaat aaccaatggg agacaatcga ccaacagaaa
    32101 tacggaatgt taaattatcc cgaacaccac ttggaaaata ttctgcatct ggtcgttgca
    32161 ttgctaaaat aatgtacatc cctgcttgac gaccctttaa tactaatggc tgaatcaatt
    32221 tatcgactct atttctcgct tccatatcca acgaaccata aaaagctgcc cattcatcaa
    32281 aaaagataaa atgcggtggt aacccataat aagcataatt tttccctggt tcatatttag
    32341 gatctttcat ggttttcata taggcatacc gttgattcat ttcttttaat gcatttcgta
    32401 aacaaataat catttcttca tttattttgt aaaacacatg tcctttgaat acatcgacgt
    32461 cacctaatgc tgctaaatct gccgcttttc catcgcaaat atctactgtc ccaacactta
    32521 aacaagcttg aattaaagaa tacaataaat aggttttccc accaccgatt gcaccagcaa
    32581 tcaacatatt tggtgattga tcatataccc aatccaaagt tttcattaaa tgaatacgtc
    32641 cattttctgc tatacattga tcaataggaa tccgaccaga atctgaaagg aatacataat
    32701 tgattcgggc tttttctcgt tcttcacgaa ttaaatcacg caaaaatact tcagataaca
    32761 aatgacccat ttttaaaaat cgttcgtgaa aacgcccacc atctaaagga aaagaaacca
    32821 ctaattcttg tttcttttga taaaaataaa cttttggtaa tctcattttt tcccttgttt
    32881 gtttctcact aacttgtttc tttgtataaa caaaccgatt gtcaattaac attcgaacaa
    32941 gtaactgacg ccaataaaca gaggcaaaat atccttcttt tagtcgcgac caatgcatca
    33001 accctaaaat taacccacta accagcaaca aatacaacac aatacttatt ccaggaataa
    33061 gatacatttg ccaattcgaa aacgtactta aacgtggata aaatactttc caactaaacc
    33121 aacctaacag aatcaaaaat ggaaacaaaa agaaaccata atagcaaaac cataaataac
    33181 gattgaaata gcgaattcgc cgaccacgat acttgaaaaa atgagctttc aattgtcaca
    33241 ttcctccttt ctgtttttac ttttcctgtg ctaaaaactt ttgacaaaaa gcaactaata
    33301 caggaatatc acatttagta aaaaaacata atcgaaaaag atttaatcga tttttataag
    33361 ggtgtgcaca catattacat attcgtacta tacgaatcca aatcacttcc tgatgatctt
    33421 gtttccactg gtacggtaat gaaaaacgaa caagatcacg taaaaacata cactgcccaa
    33481 taaccgcaca aatatatgca tttgtttgta caaaaatcgt tggattgtct ccaaaatact
    33541 caatcaattg ttggatattt tgataacaag cacaatctct caaagtattt gattggtttt
    33601 atctgaattc aaaatctccc cttccttcta tcttagataa aaagaatagg aagactcctt
    33661 cctattcttt caaaaaaacc ttattttttc tctttttcct tagaatcaac acttggttgt
    33721 ttttgatcta aacctttttc ttgtgattgt ttcatattag gattatttgt tggagcttct
    33781 actttctcta atcctttcgc ataaatcact aaatctgaat attcacgatt gccatcttgt
    33841 gctggaatat ataccacatg atattctgga tcaattaatt tcacaggatc acgtcgttta
    33901 aaaccagtca aatctacatc tgctggaaat ttaactcgtc gtgcaatctt tggttcatct
    33961 ggatttccaa aaactaattg tgctcgctgt gatcgaattt ctcccgtata atcgcctgtt
    34021 tcattatcaa atacacgatc agactcttct aatgcgccaa agcgtacggc tcctaaacaa
    34081 gtttcatcta atgcttctgt aatgtcataa ttatttggaa attttaatcc catcttacaa
    34141 aacctcccca atttttacac cagttaaaaa gacaccaaca tcttgatagc cagttgttcg
    34201 acgctctgtt tgtcccatat catttgtttc acgactattc actcgttctt tacgaaaaac
    34261 aaaataagct tcttcaaatg aaatacgcac ctctttttct ggtaatcgta atcttttatc
    34321 ctcttcagct gtgagataaa caaaaaaagc aggctgttct tctcgcgaac actctgcttg
    34381 taattgaaca tatcgcccag acacaccatt aatttccttt ggtggattag gttcccgtga
    34441 acccaataaa aatacttgac ctaaaaactc tttcttcata cgcaatgctt tttctgccat
    34501 aaagtttttc ctcctcttaa aaaccaaaat aaattctaaa tatttctaca ttacaatcaa
    34561 acaagcggtt aaaaatccta accgcttgtt cctcatgact aatctttggc tttacgtact
    34621 ttataaagtg ttatacctaa agcaatgact aatactacta atccaagaac cataagtata
    34681 ctacttgttt gttcacctgt ttttggcaac attggtacaa cagtagctgg tttaacccgt
    34741 tgttctggtt tcactggttg cggtggtttt ggcgcttcca caatttgaac cgtttgatct
    34801 ttgtttgtta gatctacatt gtgtttcgcc acttcttcaa acgtttcttt ctcatcttcc
    34861 gttttcgctt ggagccattc cgcaaaactc aagccttttc ctgcaagatt gcgaccgtcc
    34921 actaagaatt caaataagaa ttccatcatt tctttatcgg ccgcaaagac tttttccgca
    34981 tgagtgcctt caaatggtgt gccgtctggt gttaagtagc cttgaacaat taagcgatag
    35041 atttgaccaa tcgcaagacc gtctactttg acccattcaa gcacagtttg atttggcaag
    35101 gccaagatct cttttccgcc atttttattc gtcgctttcg tcgtaatggt tggattactg
    35161 attttgatgg tttggtcatt gtcggtaata tctgcgtgag aagccaataa tacgccttct
    35221 ctaaacagat cttcaaagac cacgacttct ttgcctcgca acgcacgtgc gtctagaata
    35281 aagtctagat tgactgtacc atccgttgtt tctgccacaa acgttaaggt acttgtgact
    35341 tcttttccat ctactagcac tggtttttcc gttactttgt ccattagaac accgttgact
    35401 gtgtatgttt ttccaacgac caaatcgtgg tatttcacag cgtctgtaat ggtgactttc
    35461 gttaatggat taacctcttt caagccagtg ggtttatgtg tagccgttgt acgtacactt
    35521 gggttagtta ctcgtaccgt ttgccctttg tcgttgatgt ctttatggtt tgctagttct
    35581 tcatcatttc taaaaagact ttcaaacacg acgatttcac gaccatttat acctgtcaaa
    35641 tcaaaggtaa atggtacgat caccgtttca ttttctgctt tggcaataaa gccaacactc
    35701 gtttctaccg tatttccatg cacaagcaag ggttcaccgg ttgctttatc cattaagatc
    35761 cctttgacca agtatgcttt tcctggaaga atctcggtaa tttcaacggt atcgtttaag
    35821 gtaaacaatc ctgttgggtc tgcgactgtc aatccgtctt caaagacagc cgtggtatga
    35881 acggttggat tattcacttt cacactttgg gcttcatcgt tgatatccgc atgtgctgca
    35941 acttcaatgc catcacggaa aagtttttca aaaacaacga tcgtttgacc tttcagaaca
    36001 ctagcattaa ccacaaattc aaggtctttt gtgccattga ctttgtctgc aataaaggcc
    36061 aaggtacttg tgatttcttt gccatcttgt aaaattggcg cattcgttgc cttgttcatc
    36121 aatactcctg aaatggtgta ttcttttccg acaaacaagt tggtataaga aacactgtct
    36181 ttaatgacga tcgtttctaa tggatcaacc actttttcac catcggcttt atttgacgct
    36241 tgtgtttcta gttttggtgg aatcaagtaa ttacgtacag aaaccactaa cgtttcccca
    36301 tcatctggcg cattttgttt gaatgcaacc gtgaatgctt gtttatctgt atttggttgg
    36361 aaactttcta atggggcatt ttccaagaag taatagtcat cggcaactag acctttcact
    36421 aaaatttccc cgttttgatc agtggtatat tcaccaattg cttgattttt accgttatac
    36481 aaggtaaagt tcacacctgc gagcggcgtt ttcttcttgt tccattcttc atacttgaat
    36541 aattttacac ttttccgtgc ttgacggttc gcaaaatgga tcactttgat cggttctgta
    36601 tcattggtaa tcgagaacac taatgggttt tgattcaaaa cgtaatttac gggggctttg
    36661 atttcttcca aacgatagcg atcttttcca taagtaagtg taccgttagt taggaaaaag
    36721 cctttttcat tggttttaaa gatatccgtt gtttctgtat catttggaat ctccattgtg
    36781 acataacgat tggctaaagt atcaaaaatc ttgaattctg tattagcaag tggaatcact
    36841 tttcctgttt cttgatccac tttcaccact ttaagacgtt gttcaattac tttatcttct
    36901 aaaacataat ggaaagtttg cccattttca gaaattgtga cttcaagtgg ttcaaatagt
    36961 ttataccctt cttttccttt ggtttcagaa agaatgtacg tatcaaagac aacggtattt
    37021 ttaccaaaag tagcataacc atcattgtct gtcacaacgg ttttcaccac tttgccagtt
    37081 gtttttgacg tcaaagtgat ttcaatgcca gctaattttg gtttgttatc tggattcgtt
    37141 gaatcgacta aatctttatt agcaactttc actaaatcaa tggttccttt gatcacttga
    37201 tcttttgcgg tcgcattgac agtttttcca ggttcaacaa caatttcaat tgcttcatca
    37261 gaaagcacat aaccttttgg cgctttgatt tcttttaaaa catatttgcc aggatcaaga
    37321 tctttaattt ctgcctgtac tttgccgtta atttttttca aggtaatttc tttaatcttt
    37381 ttcccatctg cttgatacaa accatagacc gcattttcta aagaagctgc accttgtgct
    37441 ttcacaccag tttccgcatc ttctttaaac acacgaatgt ttccttgttt tagaatttgt
    37501 aaattaataa cagacgcatt aggttctgtt ggatgtaaca caccaattgt ttgagctcct
    37561 ggacgacgat aggctaatgg cgcaccttga actttaattt tattcaattg aatttttgct
    37621 ttatccggtg cctcttttgt gactgtaatc catacttcat tgccgtgaat agatacattg
    37681 acaccttttg gtttttgaat gtctttcaca tatttcaaaa aatcattttt attctttact
    37741 ttcaacgttt cgccaatttt taccgtatgt gtttgattat taaaagttgc tttttcacca
    37801 aagttattaa tcaaacgttg aatttctgct tttcgacgat cataatcaac acggatattt
    37861 ttgattggga tttttgtgcc caaagcttcc caaatcataa attgtgccgc aatgtattgt
    37921 tcatcggatt tgtctttatt tgtgacatat cctaaataag agatcaagct tgtttttttc
    37981 cgtacatttg aatttttcaa atagtttttc aaagcagtag ctgtataaac ttgaccttct
    38041 gcggctgaga caccaggctc aatacaaaac gccacttgtc cattaatctc aaaacgaacc
    38101 atataattta aagtgaagtt tagattgttc ggactagaag taacaccaat attttcgccc
    38161 caatcaattt tccgaccacc taaaacagct gcattggttg cacggcgaac acgaaccgaa
    38221 cgattggttg gtactgttac taacagtgta ggtgtacctg tttttggaat gttctgctct
    38281 tttttctttt gattttcaat actagccgta gattctttgt ttggtttcgt tggttgattt
    38341 tgactagctg cggttgaaga gattgttttt tcaacgtttt cctcattttt tccttctttg
    38401 tcagcagtag ccgctggttg ttccactgtt tcttctattc gtttcttttc ttccgcttgt
    38461 ttctcagaag actctggctg cacagaaggc gttgcttcgg cagctttttc tccttctaga
    38521 gtggacgttt ctgaagcagg ggttgtaatt gaggcagttt cttcaactgg ttgtgaagta
    38581 ccaggactat tccctgggtg ttgtgtttcc ccaatcgtct gatcgagagt cgttttggaa
    38641 ttgaccgttg gcgcttctgt cacaggggcc tgttcaacag tggcttcacc agctgggacc
    38701 ccggcttctg ctggttggac ttctgtcact tcagaagcga cttgggcaat ggcttccatc
    38761 gtaggttgta tagccgtcgt ttcttctgca tgtgcttgag cagttcccac caagaaacag
    38821 aattgagaaa aagccaccaa tgcgagtgct ttcaaccaat tcattttcgt ttttgcatac
    38881 acaagaattc ctccttttcc tgagaatttt atataataaa acaaaacgcc gttaccaaaa
    38941 gtgataacga cgtgaactgt ctcttctatt tttatctggc gctcttatct gaacacattt
    39001 catcaatgat tttaccctcc cactataatt acagaacaaa aaaagaacct gcttcgtgga
    39061 aatcaactgt ccatttccca attggaatac cagctttttt ggcaacttca ccatcaccaa
    39121 atctcatgcc ataccaatta ctaccttcat ccttaatttc tttccaacca tatgacatag
    39181 cttcatctaa tgaatcaaaa atcatgacac tattgccaat tgttacagga tctggcttaa
    39241 gatcttctgg aagagaaata tcaatcatac cataatgatc cgattcctca gtattattgt
    39301 cattactagc tactggtttg gttgttctac tggcttattt tgatacaaca agtactctta
    39361 ttcttctttt acttctccgt tttcaatttc ccattcaaac cactccgcaa agtcttgctt
    39421 aaaaccatct actcgatacc tattttgtaa ataggcatct tctgacgtcg taggatctaa
    39481 ataggtaggt ttattctctg gacgagcata gacacctacc catgtttcgt aatctccttc
    39541 aaaataacta tctaccaaat agcctttttt tctaagaatc tcccgaactt gatttttaat
    39601 tattgatact tgttcaaaac catcactcat tctatcacct caaataactc tagattctca
    39661 taaatattcc cgacaatttc aatcctatca atgatctcta acaaatcgct acttatgctt
    39721 ccccattcgt ataagaattt cccttccgca aaataaattt tccataaact tcttcatgat
    39781 cgtcccaacc aatatcactc tcgaaaaatt ccacgttgtt cttatctttt agctcagtaa
    39841 atgccataag ttcaacatgt tttccaacct cgaaacaatc acaccaccca tcaaccgtta
    39901 cacgtgtgcc ttcaatacct aagaaacttt gtcctcgtgt attaaacact aaaactttcc
    39961 gcattttttg ctcattaatt aatcacgcgc gaaatctagg aatcacaact tattcgcttc
    40021 ttctttataa ataaaaaaac tccaataatc ggaaattact atcttttcct cattcctttt
    40081 ttaaatcttc atacttcttc ttatctttgt cctaacctaa taacacaaat tttgaagaaa
    40141 aactcagtaa aacctgattc tttttttatc ttcacaacaa ccaacttttt cttcagatcc
    40201 ttttactaga acttgtatac aaaaattgtt gaatgctgat ataatttgcg gctacttgaa
    40261 aaaacgatag atgtaaaaag ataaatagaa tcatttttta ttctatatca gtctatgatt
    40321 cattgcttat caatcaccca acccattcga tgccgttttt tttagagaaa tttaaaaaag
    40381 accgtacgaa tctcgcatta tccgattact tttccagaaa agatccccaa ttctgtataa
    40441 ataaccctat cttcttgttg gtttcatttt ctcatataag aattcagtca atctacccac
    40501 tatgaccatt actacgtcca acacaactga catattaacc acgtaagtat tccctcacag
    40561 atctccgaat ctccatggta tggattccca tcctgacgct gcagaggaca acatatttca
    40621 tgtggctctg tacccttttg atttggaaac actacaaatc aatactcatc tataacttat
    40681 caagcgaact ttcgctaggc ttctagtgat tactaaattg ttggataaca tacatagccc
    40741 attttatcta gctgttattc ataacagtta gttcttgtat tacttcttcc gcttgtgttg
    40801 ccattgagct tgtcaaaaag ttacttagaa aaaagctgcc agtaaagcaa ctttcaacaa
    40861 accctttttg tttcttatca tatcaagaaa cctcctttta taaatttttt ctataataaa
    40921 aaacgtcgat aacttaataa gtatcgacgt aaactatttt tatatcccgt aaatcaaaaa
    40981 ttctaaagaa agatttccta tataagcata ttggataatt cgattagtat tgggtatatc
    41041 tctaccattc tcatacctat ctatggacca ttttgaaatt gaaggagaaa aaagctttcc
    41101 aaactcctcc ctttctagat aataatcttt cctaattttc ctcatcctta atcccatact
    41161 aaaagaattt atctttttaa aatcgctaac tctttcatct tttggaagta tattcttata
    41221 atcttctccg tacataaggt aaggaacagt gaccttacca agataggcaa tattcattag
    41281 tttttcaata tctggaatat taataccttt ttcccatcta cttataacat ttttgcctgt
    41341 atagatggta aagtttttac caaatttttc aagcgtctct tcccggttct ttcggacttc
    41401 tcgtattctt tttcccataa caattttatc gtcttttgat aaactaaata tctcactatc
    41461 acgattaatc tccttcaaaa tttctttttc attacttaat agaaaaatat cgattttttt
    41521 ttgcatttct tttgacggat ttctctttct atttaacaca taactgagta atacttcact
    41581 aattcctata ttatcagcta actctttgtt aagtaactta ttcatatctc tgtatgcaat
    41641 tagtttaccg atgagaatct caatcttatc ttcctcatct tttattagag tttctatatt
    41701 cagaatcttg cttagagtat tatctacgtc tttagggatt tttcttgacc ctttttcata
    41761 tttaactaaa gtactttgtg aaatacctgc taaatcagct aacttttttt gagatagttt
    41821 tttctctttt cttagagatt taagaaccct tccacttgaa ttatcaacca tgaaaaaagc
    41881 acctcctatg agatgctttc atcatatact gacagctaaa aatcttcaag aaaaatattc
    41941 caattttgtt aattttagta tcgccgtgat aaccaaatga cagtttaaaa tcttttatac
    42001 agataatcct cagtgttgca tctactcaaa aaggtttatt taataggttt ttcgattgat
    42061 tataagttat ttcacactat cttgctcatc cattttcaga acggccatga aggcttcttg
    42121 cggaacttcg acggagccga tttgtttcat ccgcttcttc ccttcttttt gtttctctaa
    42181 gagtttacgt ttacgagaaa catctccacc ataacattta gccaagacgt ttttacgcaa
    42241 ggctttgatg tctgaacggg caacgatttt ttgtccaata gctgcttgga ttggcacctc
    42301 aaattgttgg cgtgggatta gttttttcag tttttcaacg attgcttttc cacgttcata
    42361 ggcaaagtct cggtgaacga taaagcttaa tgcatcgact ttttctccat tcagcaagat
    42421 gtccatcttc actaacttgc ttttttgata accagacatt tcataatcca atgaggcata
    42481 gcctttcgtg cttgatttca atttgtcgaa aaagtcaaag acaatttcag aaagcggaat
    42541 attatagacg acatttactc ggtaatcatc taaataatcc atcgtaatga attctccccg
    42601 ttttcgttga gaaagttcca ttactgcacc gacaaaatca tttgggacca tgatctgtgc
    42661 tttgacgaat ggttcttcta catcctgaat cgttacaggt tcaggaaaat ctgccgggtt
    42721 atctactgta gcagtcgtac catccgtttt attaacatgg taaataacgg atggtgcagt
    42781 cgtgatcaat tctagattga attcccgttc caagcgttct tggacgacat ccatatgaag
    42841 aagtccgagg aatccacagc ggaacccaaa acctaatgct tgagaggttt ctggttcgaa
    42901 ttgtaaagca gcatcattca attgcagttt ttctaaagct tcccgcaaat cgttgtaacg
    42961 agaagtatca attggataaa gaccacaata aaccatcgga ttcatttttc ggtaacctgg
    43021 taaagcttca gcggcaggat tgtctgctaa cgttactgta tcccctactc gtgtatcttg
    43081 gacagttttg atacttgctg tgatataacc gacatcaccg accatcaaaa agtctctagc
    43141 aactgctttt ggcgagaaga ccccgacctc tgtaacatca aatgttttgc cattactcat
    43201 cagtttgatt ttgtctccgg gtttgaccat accgtccgtg atccggacat ttagaacaac
    43261 accgcggtaa ctatcataaa tagagtcaaa gatcaaagct tttagcggtg catctaagtc
    43321 tccacttggt gcaggaacat attccacgat ctgctcgaga atatcttcaa tcccaatccc
    43381 tgatttggca ctggctaata cagcttcact agcatcgatt ccgattacgt cttcgatttc
    43441 ttgacggaca cgttcgggat ctgctgcggg taggtcgatt ttattgatga ctggcaggat
    43501 ctccaaatca ttgtctaacg ctaaataaac attggccaat gtttgtgctt cgattccttg
    43561 tgctgcatcg accactaaaa cggcaccctc acaggcagca aggcttcgag agacttcata
    43621 ggtgaagtcg acgtgccctg gggtgtcaat caagtgaaag atatatgttt ctccattttt
    43681 cgctgtgtaa ttgagttcta cagcatttaa tttaatcgtg attccacgtt cacgttccaa
    43741 atccatcgag tctaacagct gatcttgcat ttcgcgagac gtcacagtgt gcgtcatttc
    43801 taaaatacga tcggccaatg tagatttccc atggtcgata tgagcgatga tcgaaaaatt
    43861 acgaatctgc tcttggcgtt ctttcatttt ctttatatcc atagcgtctc ctcttttcat
    43921 ataatcagca ctttccatta taccaacgaa aagcagtaat ttaaagagtt tttaattagt
    43981 cagctataga agtttttttt gtagaatttt gctatactgt tatcaagcta ataaatggag
    44041 atgaaaaaat ggatcaaaaa gattttagag aaaatcttga attaaaaccg gtcactcaag
    44101 aacatatcga tcaattcaat gaattgcttt cctatgtgtt ccaagtgact gaagcagaca
    44161 tcgaggaaag cgggtttgag aataaacgag cttttatccg ttccaaaaaa ccgattttgg
    44221 aagtatcgaa agtgttcgga tggttccacg aaaataaact gatctctcaa atcgctatct
    44281 atccttgtga agtcaatatt cacggtgcac gttataaaat gggtggtgtg actggagttg
    44341 gaacttatcc agaatatgct aaccatggat tgatgcaaga tctaattatc gttgcattgg
    44401 ataatatgcg caagaataag caatggatct cttatttgta tccttacagt atcccctact
    44461 atcggcgtaa aggatgggaa atcatgtctg ataaactttc ctttaaaatc agagatacac
    44521 agctacctaa acaaatccca gtaagtggta tggttgagcg attaccagtt gatcatccag
    44581 acgtattttc cgtttatgac aaatttgccc aacaaaacca tggtgcttta ttccgcagtg
    44641 attttcattg ggaagagtat tggcgtttcg aaaatgaaga tgagcgcaca gccgctgtct
    44701 actacgatag caaccatgaa ccaagaggtg ttctgttcta ctgggtagct gaagaaatat
    44761 ttcacgtaaa agaaatgttc tatcttgatc aagaagctcg aaatggctta tggaacttta
    44821 tttccgcaca tttttccatg atctactggg tacatggaga tatttataaa aatgagcctt
    44881 tagcattttt gattgaagat agtcagatca aagagcagat cgaaccatat tttatggctc
    44941 ggatcgttga tgtaaaagaa ttccttcaac ggtttccgtt tgttggaaca gctgatgctt
    45001 ttcatttcat cattgaagat cctgtcgctc cttggaataa tggtgtcttc gctttaacat
    45061 gggatgaaca gggacaagtc cgtgtcttaa atgaacctat aggaaaatcc gttcgactgg
    45121 atatccaaac attgacttgc ttgatgatga attatcgccg tgcttcttat ttggcaagaa
    45181 tcgaacggtt agaaacagat gaagaaacac tgaagtcact agagcgtatc attccaaaca
    45241 tggaagctta ctttagcgat tatttttgat aaaaaggatg atgtttagat gaaaatttat
    45301 tttgccgcac caatgtttgc taaaagtgat ttgttatata accaacagtt agttaaagaa
    45361 atcagagagc tctcttctga gctttcgatc tatcttcctc aagaaaatga agcaatcaat
    45421 gacaaaactg cttatgcaga cagtcgaatg attgctcttg ctgacacaga aaaagtgttg
    45481 gctagtgatt taatgattgc tttactagat gggctgacga tcgatgccgg ggtagcatcg
    45541 gaaatcggtg tggcttatgc gaaaggcatc ccagtgatcg gcttatatac tgatactcga
    45601 cagcaaggcg gaacccaccc gaaaaaaatc gctgcactac aagaaacagc tgaaaatcaa
    45661 tttcactacc tgaacttata tacaataggt ttgatcaaat tgaacggaaa agtggtttct
    45721 tcagaaattg agttgctttc agaagtaaaa agatttttag atggagggac tttcagtgat
    45781 taaagaaatc aaaaaggtgc aaatagcttt acttgctttt ggtgtattcg ttgtctgcta
    45841 taatttttat gaatttatca cacaaaaata ttcgacttct caaggaatca catttatcgt
    45901 ggaatcttta ttagggattg cattgatttt catgccacaa gtcattttga aagttttcaa
    45961 acttaaaata ccagcagcaa tcgttttgtt ttactggttt ttcttgttca tctctgtctt
    46021 tttaggcaca gggatgcatt tgatcagtat catctctttt tgggacaaaa tcttacatgc
    46081 ggtgagtcca atggtcctga cagctcttgg ctatggattg attggttact tgatgaaaga
    46141 tgctgagata tcaaaaacca gtccttggtt gttcctctta ttcggctttg cgtttgctgg
    46201 actttgcggc gtgttttggg agttctggga attcttatgc gaccagttct taggcatgaa
    46261 tcttcaacgt tttgctgctt ctgatggcac actgtttgtc ggacgagcag cattgatgga
    46321 tacgatgggc gacttgctga caaatacgat aggtgctgcc ttaatgggat tgtttgcatg
    46381 gtctcaaagt aaaaaagatg agcgttactt tgaaagttat aaattagaaa aagtgaaaaa
    46441 tacctaataa aagaggttgt gacagaagcg ggcagcttca agaaatttcg gcttattttt
    46501 cgaagaaact acttctggaa cactgtttat ttgaaaaaag gaggtctgac actagttgtg
    46561 tcagacccct tttttctttt atagtctcaa tggaagatta gacgatttct tctagctctt
    46621 ctgttttgaa atgaagttgt ccatcaagta aagtaatcgt tacttttgat ttaggcataa
    46681 catgtcctgc aacgatttct ttagctagtg gtgtttctac ttccttagtg ataaatcgtt
    46741 tcaatggtct tgcaccatat gctggttcat aagcattttc agcaatccac gttttggctt
    46801 catcactgat tgtcagcagg atttcttgat gttccagacg ttgtgccaat tgcgccacca
    46861 ttttgtcaac gattcctttc acgttgtcta ggctcaatgg tgtaaataaa atcgtgtcgt
    46921 cgattcggtt caagaattct ggtttgaagt ttccacgtaa tagcgtgttg acttgttcag
    46981 ccactgcttc tggaatcgtt ccatcagcag tcacgccttc cagcagtaac tgtgaaccga
    47041 tattgctggt catgatcaga accgtatttt tgaaatctac tactcgccct tttgaatcag
    47101 tcaagcgtcc gtcatctagg acttgtaaca agatattgaa gacatcggga tgcgcttttt
    47161 cgatttcatc caacaagacg attgtataag gatttcgtct gacagcttcc gttaattgac
    47221 caccttcttc gtaacctaca tagcctggag gagctccgac tagacgagac acagcatgtt
    47281 tttccatata ttcactcata tcgatccgta ccatatgatc ttctgagtca aacaagttct
    47341 cagctaacgc tttcgctaat tcggtttttc cgacaccagt tggtcctagg aaaaggaaag
    47401 aacctagagg acgatttggg tcttgcaatc cagcccgtga acgaattacc gcgtcactga
    47461 ccgcatcaac tgcttcatct tgaccaatca ctcgtttatg aagtgtttca ttcaatttaa
    47521 ttagtttttc tcgttcacct tctacaagtt tcgttacggg gatacccgtt aatctgccaa
    47581 cgacttgagc aatctcattt tcggtaacgg actcttgaac catcttaatc tcgctgtctt
    47641 ttgctttagc ttctaattcc ttcaattctt tttctaattg aggtatcgta ccatgacgca
    47701 atacagcagc gcgttctaaa tcatagttat tttctgcatc ttctaattcg tgttttgctt
    47761 tatcgatttc agcacgtttt gctgaaacag aattgacttc ttctttttct gtttcccact
    47821 gcatcttcat cgcatttgct tcttcacgaa gttcagctaa ttcttcttgc aaatttttca
    47881 agcgtttttt acttgcatca tctgattctt ttttcagtgc agcttcttcg atttccaact
    47941 gcatcaaacg tctagtaact tgatctaatt ccgttggcat agagttcatt tctacccgaa
    48001 tcgttgcact ggcttcatcg atcaaatcga ttgctttgtc cggtaagaac cgatcagtaa
    48061 tataacggtc agataaagta gctgctgcta ctaatgcgtt gtcatggatg ttaacaccat
    48121 ggtggatctc aaaacgttct tttaatccac gcagaatact gatcgtatct tccactgttg
    48181 gttctttgac taataccttt tgaaagcgac gttccaacgc tttgtctttt tccatatatt
    48241 gacggtactc atctaaagtt gtggcaccga tcaaatgtaa ttcaccgcga gcaagcattg
    48301 gtttcaacag atttccggca tccatacttc cttctgtttt tcctgcccct acgatattgt
    48361 ggatttcatc gatgaacaag aggatacgtc catcactttt tttgacttct ttcaagactg
    48421 cttttagtct ttcttcaaat tcaccacgga attttgctcc agcgatcaat gcacccatat
    48481 ctaatgaaaa aatcgtttta tcttttaaat tttcaggcac atctttgcgt acgatacgtt
    48541 gagcaagccc ttcaacgatt gccgttttcc ctacaccggg ttctcctatc agaacaggat
    48601 tattttttgt ttttcgtgaa agaatacgga tgacatcacg gatttcttca tcacgaccga
    48661 tgattggatc catttttccg cttttgactt gctgtactaa atcaacgccg tatttttcta
    48721 atgctttgta ttgttcttct tggttttgtg aggtcactct ttctcctcct ctcatctctt
    48781 cgatgttttt acgcaattct ttttcagata atccgttttt attcaaataa acagttaacg
    48841 gataattttt taatttcatc aacgctaaaa taacgacttc cgttgaaaga aactcgtcgc
    48901 cgaagctttc acgtatttgg tctgcttcat tcaataatcg aaagaaattc tggctgaggt
    48961 tttgtccata ttggacgttt ccaccagaaa caactggata ctcatccagt agacgatcaa
    49021 tttcatgttc aaaagattcg acatccaatc cggcatccgt atagaaattt cgaccaaaat
    49081 gattagattg taaaaagatt ttccatacat gggcaatgtc gatatcttga tgttttcgag
    49141 tgaccgcaat ctgttgagct tcagcaatcg cttcttgaag cgtcgtagtc attttctcaa
    49201 tattcataca ggtataccct cctaattaaa ggtaagatca cttatttctt tgatctttac
    49261 aaaaactatt atatcgcttt ggtcaatttt ggtcaaaata tacacatagt tttttgactt
    49321 tttttctcga cttatataaa tcttaaaaaa acaaaattga ttgtatgtat ataaaaaaag
    49381 agccaaacaa acgtaaaatt atcttatcca taacgttttt ctttgatttg ataaaaaggg
    49441 tagatcttat aaaagaccta cccttgattt tctttattct ctttttttac ttctattatt
    49501 tcttctttga tcactcttcg ccgttcagca atcacataca caaatccata gagaaatggc
    49561 aagataaagg aactgaaacg atacagtaaa agcgaagaaa ctgcgtcaac tgttccaaca
    49621 actggtctga ataataacaa atagacaaat tcaaaggaac caataccagc aggcgtagga
    49681 ataacccctg aaagcactac tgcaaagctg ataaacgaaa tggtcagtag aaaatctatt
    49741 ttaggatggt tttcaatcag aatcaaataa ggaagtacat accaaaatac aagttttaac
    49801 atattccata gataaatccg caatagcgca gtcctgtctt ggataatggt ttggaccgtt
    49861 tcccttaaag agtagatctg ctgattgcat gtatccaccc atttccgcaa acgctcactt
    49921 ttaaataact tattcgataa gctgacaaaa aatatttgaa cattcaagct gacggacatc
    49981 gccaataaaa aggcaacaat cacgatcgtc aaaaggatac cagcgatgat aaaccagatc
    50041 attgatggac cattagaata aaaaagagag aattggatga ccaagccagc taatgcataa
    50101 gtgatcactg ccagtttgta cataatcata tggagtgctg tcacccctgc tccctgggat
    50161 agcttcattc cttttttgtt ataaaaataa atctccgaga tcagcgttcc tgtaccaaac
    50221 gaaacgattc ggtaaaacgc aatatagcta gaggtcaaga acccatcttt cgttgtaaaa
    50281 ttcggcgcga aaggttcagc aatttctttg attgagcgcc cttcagcgat ttggtaaact
    50341 gtccctaata taacagccgc tgccaaaaca acaacactgg tagacagcaa ttcggcaaag
    50401 atatctgcaa atgattgatt gattaaataa taaataatgg caaaaatcac aatcagcaaa
    50461 agcagattca gaatgatttt agttttcgtt cctttagacg acatctcctg ctccttaatg
    50521 gaaaaaataa atgagaatca aatcaacaag tacacctgca gcgaatccta tagtaaactt
    50581 ctttttccga gttttatgat ggaaaacttt tcgagagatc aatcctccca aaccaccgcc
    50641 taacaggctg acaaatatca aattattctc aggaacacgc cagccgctag ttctagcctg
    50701 atgtttatca taccccatca gacaaaataa gtaaaaattc acaatgaaaa ggtaaaacca
    50761 caaaggattg tgtaacaata catccattac tcttcttcca actttctgtt aactactatt
    50821 tctaagcttt ttcttctttc tttggtgaat aaactgttaa tccttttgat acaacagata
    50881 attcaactgg aagatcatct gtcgtgtctc catccgttcg agtgcccaca gatttttcct
    50941 gcgcttggat tttcatgcgt ttggctgtga aataagtaat gccggggatc gtatagaatt
    51001 tgcctctcat gattctaggc aaataaaaaa taaatcggaa aatatctaag gaaggtacga
    51061 tcgttacatg aaattttcca tcatctaggg tcgctgagtc gtcaaaattt gtaaaaccgc
    51121 ccacggagtt agacatcgtg actgtcaaca gttgggattt tcctttccaa tgctcctcgt
    51181 ctgtttctaa atccaaatga tattttttct tcttcagcaa taacttaaaa aacttcttga
    51241 taaagatcca cgagccgtaa cgctgttttt cttcttgact gatccaaact gctgtatctg
    51301 ctaagattcc gattgtcagt gtagagataa tgacttcatc attgacttga ccatagtcta
    51361 ttttccgtac attgccttcc aggatcacgt cagcagcttc ttcttttttg aggggaatct
    51421 caagaacacg tgcaaggttg ttgacagttc cacctggaag taatccgaca tggtattgag
    51481 ataatgtttt ttggaacgct tggacgatat gatgaatcgt gccgtctcca cctataatta
    51541 ctaaagtatc agcttctatg gcttctgctt tcttgactaa ttccgcatca tcaatcgatg
    51601 ggccagtttc agctagttct acatataatt ctggctgctt ttcttttaca taatcttgaa
    51661 accagcgtgc taatttctca ccctcatctt tccctgaact tttgttataa aaaactagca
    51721 gcttttccat tctttacctc ctatttactc ttcaaaaaag agggcgggac aaccaattcc
    51781 attgtcctgc cctttagcct tagacagatg acattccatc attgggacga acgccttgtc
    51841 ataagctgtt ctttttcgat tttaactctt tgtgttcaat tctgcaattt ttacaatcac
    51901 gtctgttgct ttttccatta cttgtaaaga aacaaattcg aatcgtccgt gcatattttc
    51961 tcctccggca aatagatttg gcgtcggaat acccatgtaa gagatttttg aaccatctgt
    52021 tcctccacga actggttcga tcactggaga gataccaagc tcgatcattg cttgtttcgc
    52081 taattccacg atgctcatat ctttttcaat gatttctttc atgttgtaat attgatcata
    52141 catatctact ttgattcgtt cttgatcaaa tcgctgattc aactcttctt ggatatgtgt
    52201 gatttgtgct ttgcgtgctt cgaatttttc acgatcatga tcgcgaatga tataactcat
    52261 agaagcttct tcaggattcc catccaatgc catcaaatgg aagaaacctt cgtatccttc
    52321 cgttttttct ggaacttcat cggctggaag ctgattatga aaatcgattg ctaactgtag
    52381 agcattgatc attgtatctt ttgccgtccc tggatgtaca tttttccctt ggatcgtaat
    52441 atttgcttga gcagcactaa acgtttcata ctgcaactca cctaaaggac caccatcgac
    52501 tgtataagca aaatctacat cgaattgctc aacatcgaat ttatccgctc cgacaccgat
    52561 ttcttcatca ggaccaaaag ccactttgat ggtaccgtga gggatagaag gattattgat
    52621 caagatctcc attgcagtca tgatttccgc aatccctgat ttgtcatctg ctcccagtaa
    52681 tgtactgcca tctgttgtga tcaatgtgtg gccttcataa tttttcaaat ttggaaaatc
    52741 ttttgtattc aatgtatagc gttcttccgc atctagtacg atcgtagact cgccatcata
    52801 gttttcaatg atttgtggat tgactcctac tgcattaaaa tctgctgtat ccatgtggga
    52861 aataaatcca atggaacgca cttcatgatc aacattgctt ggtaatgttc ccataacgaa
    52921 tccgttatct tcattataga aaacatcagc taagcctaac tcttctaatt cttttttcaa
    52981 ttcttgcgca aaagcaactt gtgtctgagt cgatggagtc gttttgcttg ttgcatcgga
    53041 gcgtgtttct gttttgacat atcgtaaaaa acgtggcaaa agattttcgt acatagtatt
    53101 ctctcctttt aattaaattg aaatgggttt gtatttgttt cagaaacgaa aaagttaata
    53161 tcccaatttt cttcttgttt ccaagattca aatttctcga taaatcgttg cttgcataac
    53221 gattcaatat aatgaccggg atcaattgca atcaacccag cgctttgcat atcatgagcc
    53281 gtatgataat agatatctcc cgtgatatag acatctgctc tttgggcgat tgcttgcgga
    53341 taaaattttt caccgcttcc accgcaaatc gcaatgcgct tcacagagga ttttgcattt
    53401 tttggctgga ctattctcag tccatctagt tggaacgctt cttttacttg ttctacaaat
    53461 gcctctatag aaatttcttg cggcaattca cctactcgtc ctaacccaaa catttcgact
    53521 ggttcatcta tagcgaaaag atcataagca ggttcctcat aaggatgagc tgaccgcatg
    53581 gcttgaatca cttgtttttc gatagtttcc ggcaaaataa cctcaacttt tgcctcttga
    53641 acttgttctg tcttccctac tttcccaatc gctggttgtg caccagcttc cggagtaaat
    53701 cgaccgtgtc caatcgaggt aaaacttgta ccggtataat caccttgtgt accagcacca
    53761 gctgcagcta atacttcacg cattttctgt gcatgatcca caggtacata aacggccagt
    53821 tttttataat gaatctcatg agtctttact aaataactct ccacttcaat accgagaagt
    53881 tcacaaaacc agtcattcag tccatcccaa ataatatcca tgttcgtgtg tgctgcatag
    53941 acggcaatat catgtttcaa caaatctgca tacatttttt cttgtggctg atcagtaacc
    54001 agccgtttta caggacgaaa gattggagga tgtttagcaa tcagcaaatc gatttttttc
    54061 ttgattgctt cttcgaccac ttctggacga acgtctaatg tcatcattac tcgttggatt
    54121 ggcttatcca atgttccgat atgcagtccg actgggtctc cttcttcagc tagccactga
    54181 ggacaatagc tttcaaactt ttggatgaaa gtgcgtccgc tgattgtcat ggctttaaaa
    54241 cctcctcaat catttggatt tcctgctcga tttgtttttg acgtgcctct tgattagctg
    54301 cttgtttgag ctgttcacgg atagcttttc tttgttgaag ctctcttgtc cattttgatt
    54361 tgaagatctc acttttctct tcaagcagaa atggcccgaa catcagctcc atttcattgt
    54421 aagtaactgg tttttgttct ttttcggcta caatgatttc atatattttt ttattttctt
    54481 caagtatttt ttctgattgg attttatact gattttcttg cagccaagat cgtaatgtac
    54541 gctctccgat gtttggctga aggatcaaac gttcttgtcc gcttaagcgt tgattcaact
    54601 tgccagcttc taggatatct cggatcagtg aacctcccat acccgcaatc gtgacagctg
    54661 taataccatc ttgtggctgg atagcatcta gaccatttgc aaggcgtacg gtgatacggt
    54721 cttctaatcc atcttttttg acttgcttac gtgctgattc ataaggacct tgaacgactt
    54781 caccagcaac tgcatattcg atttttcctc ttaatatcaa tgcaacgggt aagtaagcgt
    54841 gatctgatcc aatgtctgct aaacgagcgg attcagggac aaagtcaccc actgcggcta
    54901 agcgctgaga taaatctaaa tggttcatag cttcactcct tctagataat tatagcattt
    54961 tccaaataaa ataaggagac taggaataaa aaa
//
LOCUS       DBBGSZ010000017        50060 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.017, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000017 DBBGSZ010000000
VERSION     DBBGSZ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 50060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50060
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.017"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(313..2205)
                     /locus_tag="ACIZE5_001372"
     CDS             complement(313..2205)
                     /locus_tag="ACIZE5_001372"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6108523.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2202..3929)
                     /locus_tag="ACIZE5_001373"
     CDS             complement(2202..3929)
                     /locus_tag="ACIZE5_001373"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6108524.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3945..4595)
                     /locus_tag="ACIZE5_001374"
     CDS             complement(3945..4595)
                     /locus_tag="ACIZE5_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HGC6108525.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4799..5095
                     /locus_tag="ACIZE5_001375"
     CDS             4799..5095
                     /locus_tag="ACIZE5_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGC6108526.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5287..5907
                     /locus_tag="ACIZE5_001376"
     CDS             5287..5907
                     /locus_tag="ACIZE5_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGC6108527.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(5999..7165)
                     /locus_tag="ACIZE5_001377"
     CDS             complement(5999..7165)
                     /locus_tag="ACIZE5_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGC6108528.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7177..7530)
                     /locus_tag="ACIZE5_001378"
     CDS             complement(7177..7530)
                     /locus_tag="ACIZE5_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HGC6108529.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7658..8680
                     /locus_tag="ACIZE5_001379"
     CDS             7658..8680
                     /locus_tag="ACIZE5_001379"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HGC6108530.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            8699..8860
                     /locus_tag="ACIZE5_001380"
     CDS             8699..8860
                     /locus_tag="ACIZE5_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108531.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(9119..9553)
                     /locus_tag="ACIZE5_001381"
     CDS             complement(9119..9553)
                     /locus_tag="ACIZE5_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108532.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9663..11522)
                     /locus_tag="ACIZE5_001382"
     CDS             complement(9663..11522)
                     /locus_tag="ACIZE5_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HGC6108533.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            11523..11663
                     /locus_tag="ACIZE5_001383"
     CDS             11523..11663
                     /locus_tag="ACIZE5_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoglycerate dehydrogenase"
                     /protein_id="HGC6108534.1"
                     /translation="MLAPSFLSIKECCFSYFSCTKFESKERKEELMKSKYSLSLWPFW
                     FL"
     gene            complement(11640..12800)
                     /locus_tag="ACIZE5_001384"
     CDS             complement(11640..12800)
                     /locus_tag="ACIZE5_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HGC6108535.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(13107..14531)
                     /gene="araA"
                     /locus_tag="ACIZE5_001385"
     CDS             complement(13107..14531)
                     /gene="araA"
                     /locus_tag="ACIZE5_001385"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008733 - L-arabinose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HGC6108536.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14547..15245)
                     /locus_tag="ACIZE5_001386"
     CDS             complement(14547..15245)
                     /locus_tag="ACIZE5_001386"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HGC6108537.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15202..16863)
                     /locus_tag="ACIZE5_001387"
     CDS             complement(15202..16863)
                     /locus_tag="ACIZE5_001387"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0005998 - xylulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HGC6108538.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            17081..18481
                     /locus_tag="ACIZE5_001388"
     CDS             17081..18481
                     /locus_tag="ACIZE5_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HGC6108539.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18733..19812)
                     /locus_tag="ACIZE5_001389"
     CDS             complement(18733..19812)
                     /locus_tag="ACIZE5_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6108540.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(19898..20857)
                     /locus_tag="ACIZE5_001390"
     CDS             complement(19898..20857)
                     /locus_tag="ACIZE5_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HGC6108541.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(20869..22380)
                     /locus_tag="ACIZE5_001391"
     CDS             complement(20869..22380)
                     /locus_tag="ACIZE5_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA];
                     GO_process: GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-arabinofuranosidase C-terminal
                     domain-containing protein"
                     /protein_id="HGC6108542.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22402..22966)
                     /locus_tag="ACIZE5_001392"
                     /pseudo
     CDS             complement(22402..22966)
                     /locus_tag="ACIZE5_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
     gene            complement(22972..23835)
                     /locus_tag="ACIZE5_001393"
     CDS             complement(22972..23835)
                     /locus_tag="ACIZE5_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6108543.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23849..24745)
                     /locus_tag="ACIZE5_001394"
     CDS             complement(23849..24745)
                     /locus_tag="ACIZE5_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6108544.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(24920..26209)
                     /locus_tag="ACIZE5_001395"
     CDS             complement(24920..26209)
                     /locus_tag="ACIZE5_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6108545.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26181..27698)
                     /locus_tag="ACIZE5_001396"
     CDS             complement(26181..27698)
                     /locus_tag="ACIZE5_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HGC6108546.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            27896..28786
                     /locus_tag="ACIZE5_001397"
     CDS             27896..28786
                     /locus_tag="ACIZE5_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HGC6108547.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(28859..29683)
                     /gene="nadE"
                     /locus_tag="ACIZE5_001398"
     CDS             complement(28859..29683)
                     /gene="nadE"
                     /locus_tag="ACIZE5_001398"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HGC6108548.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(29695..31167)
                     /locus_tag="ACIZE5_001399"
     CDS             complement(29695..31167)
                     /locus_tag="ACIZE5_001399"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HGC6108549.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(31804..32166)
                     /locus_tag="ACIZE5_001400"
     CDS             complement(31804..32166)
                     /locus_tag="ACIZE5_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HGC6108550.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            32389..33141
                     /locus_tag="ACIZE5_001401"
     CDS             32389..33141
                     /locus_tag="ACIZE5_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGC6108551.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EADRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(33281..34204)
                     /locus_tag="ACIZE5_001402"
     CDS             complement(33281..34204)
                     /locus_tag="ACIZE5_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6108552.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(34219..34491)
                     /locus_tag="ACIZE5_001403"
     CDS             complement(34219..34491)
                     /locus_tag="ACIZE5_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108553.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
     gene            complement(34835..36022)
                     /locus_tag="ACIZE5_001404"
     CDS             complement(34835..36022)
                     /locus_tag="ACIZE5_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HGC6108554.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
     gene            complement(36435..38060)
                     /gene="groL"
                     /locus_tag="ACIZE5_001405"
     CDS             complement(36435..38060)
                     /gene="groL"
                     /locus_tag="ACIZE5_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HGC6108555.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
     gene            complement(38111..38395)
                     /gene="groES"
                     /locus_tag="ACIZE5_001406"
     CDS             complement(38111..38395)
                     /gene="groES"
                     /locus_tag="ACIZE5_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HGC6108556.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            38620..39282
                     /locus_tag="ACIZE5_001407"
     CDS             38620..39282
                     /locus_tag="ACIZE5_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGC6108557.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            complement(39358..40650)
                     /locus_tag="ACIZE5_001408"
     CDS             complement(39358..40650)
                     /locus_tag="ACIZE5_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC6108558.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            40820..41449
                     /locus_tag="ACIZE5_001409"
     CDS             40820..41449
                     /locus_tag="ACIZE5_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HGC6108559.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            complement(41552..42361)
                     /locus_tag="ACIZE5_001410"
     CDS             complement(41552..42361)
                     /locus_tag="ACIZE5_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGC6108560.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(42416..43285)
                     /locus_tag="ACIZE5_001411"
     CDS             complement(42416..43285)
                     /locus_tag="ACIZE5_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HGC6108561.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            complement(43286..44602)
                     /gene="yycH"
                     /locus_tag="ACIZE5_001412"
     CDS             complement(43286..44602)
                     /gene="yycH"
                     /locus_tag="ACIZE5_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system activity regulator YycH"
                     /protein_id="HGC6108562.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            complement(44599..46434)
                     /gene="walK"
                     /locus_tag="ACIZE5_001413"
     CDS             complement(44599..46434)
                     /gene="walK"
                     /locus_tag="ACIZE5_001413"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HGC6108563.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            complement(46439..47143)
                     /gene="yycF"
                     /locus_tag="ACIZE5_001414"
     CDS             complement(46439..47143)
                     /gene="yycF"
                     /locus_tag="ACIZE5_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HGC6108564.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            complement(47333..48193)
                     /locus_tag="ACIZE5_001415"
     CDS             complement(47333..48193)
                     /locus_tag="ACIZE5_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGC6108565.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            complement(48180..48749)
                     /locus_tag="ACIZE5_001416"
     CDS             complement(48180..48749)
                     /locus_tag="ACIZE5_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HGC6108566.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            49130..49202
                     /locus_tag="ACIZE5_001417"
     tRNA            49130..49202
                     /locus_tag="ACIZE5_001417"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:49163..49165,aa:Lys,seq:ctt)
     gene            49729..50034
                     /locus_tag="ACIZE5_001418"
     CDS             49729..50034
                     /locus_tag="ACIZE5_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HGC6108567.1"
                     /translation="MTIELEEHLLWFKYDPSEKFVKDLYKVWDTEVVFLAIETSLLVN
                     LHYSNKNYFKIPAVKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
BASE COUNT        14588 a        10491 c         8626 g        16355 t
ORIGIN      
        1 caagaggttg tgagcctgcc gtttaactcc gagtcacaag gagcaatttc aaaaaacagc
       61 ttctcaggtt tgttgactat tgtgacttgt gaccgaggag ttggcaggag aacaccgttt
      121 aaggaagagg ttgtaaaatc agcggtttga cctgagtatt agagatacaa aacggaaaaa
      181 tagcttctca tattttgccg ttttttgagc taataccgaa ggacagctga ttgaacaccg
      241 tttattcgga aaaagggact gtgacacgac ttttgtcaca gcccctaaaa aaaataataa
      301 atttgtacta ttctatgaag cttcttcttc agaaaactga ctgttataaa gatctgcata
      361 gaatccgtct ttttccatca atgtatcgtg gtttcctgtt tctacgatcg aaccatgatt
      421 catcacaata atgttgtctg catcgcgtat tgtagacaag cggtgagcaa caacgaaact
      481 tgtccggttt tccaataggc ggttcatcgc tttttgaatc agtatttctg ttcgtgtatc
      541 tacactagat gttgcttcat caaggatcag gacatctgga tttgctaaga atgcccgcgc
      601 aattgtgatt agctgacgct gcccttgcga aatattgctt gcatcctcgt ttaatacagt
      661 gttatatcct tctggcaatt tacgaacaaa atcgtctacg tgagcagctt tagcagcctc
      721 aatgatttgt tcgtctgttg catcgtcgtt cccatatttg atattgtcat agatacttcc
      781 tgtaaacagc caagtatctt gcagtaccat tgaaaactgt gcgcgcaatt catcacgtga
      841 aagatcacgg gtatctacac catcgtaacg aatactacct ccagaaacat cgtagaaccg
      901 ttcaagaagg ttgatcagtg tcgtcttccc tgcaccagtc ggacctacaa tagcgaccat
      961 ctcaccaggt ttgacatcca agttaaaatc agtcattagc aagttatctg gtgtgtagcc
     1021 gaattgaaca ttttcaaaac gaactttgta tggtgtatct ttttcttctg gaaggccaga
     1081 tttttcattg gacatctctt cttcatccaa cacttcaaat acccgttcgg ctgaagcaac
     1141 tgttgattgg atagtgttca tcaaacttgc aagttgagtg attggttgag agaactgtgt
     1201 tgtatattgc aagaacgctt gaacatcccc taatgtcatg ttcccatttg caacttttac
     1261 tccgcctagt acagcgacga acacatagcc tagattttta acgaaattca tcaacggcat
     1321 gatgattgcc gaaataaatt gagctttcca accagcggca tacagattct gattttcttt
     1381 ttcaaatact tcctggtctt tttcagtatg attgaatgtt ttaacaatgg tatgaccacc
     1441 atatgtttct tctacttggt tattcaataa acctaaactt ttttgctgat ctgcgaaaaa
     1501 cacttgtgat ttcggcgcta cgatcatcac gatgatcaag cttaaaggga tcatcaataa
     1561 cgcgactaac gtcaattgcc agctgattga aagcatcatc acgatgaccc caatcaatgt
     1621 gactgcacta gttacaaatt gagtcaaatt ttgctgcagc gtgcttgcga tgttatccat
     1681 atcattgatt gctcgagaca tgatatcccc atttgtatgt gtatcataat aggaaatcgg
     1741 tacacgattc attttggctt ccaaatcatg acgtaattca taaactgttc gttgggaaac
     1801 acgtgtcata ataaattgct gtaaaaagtt gaatacagca gaaatcaaat acatcacgat
     1861 tactgtcgca atgatctgcg cgattttatc aaagtctatc ggaaattttg ttacttgttg
     1921 gccttgttgc atctgttgag cgccagccat tacacctttg aatatttctg tggttgcttt
     1981 ccccaagacc tttggtgttt ggatttggaa gatcacggct gctattgcta gtacaaatac
     2041 agcgatgatc gcaaccatac gtttagacat atagccaaac aatcggcgta ccgttcccca
     2101 gaaattttta ggcttttcac cttttacacc gagatttctg ccaggtccac catgtcctgg
     2161 accgcctgct ggtccatgag agggacgtgt gtttgtttta ctcatgctaa gtcctcctct
     2221 cttagttgtg aatgaacgat ttcttgataa gtttcgtttg ttgctaatag ttcttcatgt
     2281 gttcctttgc caaccagttt tccttcatct agcacaagga tcatatctgc atccattact
     2341 gtacttactc gttgagcaac taaaacggtg atactttctt tcatattcgt tttcaatgct
     2401 tggcgaagat tggcatccgt tttgaaatcc aacgctgaga aggaatcatc aaacacatag
     2461 atatctgctg ttttgactaa tgcccgtgca attgccagac gctgtctttg tccaccagag
     2521 aagtttcctc ctccttgttc cacatggcta tctaagccat cttccatctc tgaaacaaaa
     2581 tctttagctt gtgcgatttc taatgctttc caaatcattt catctgttgc atccggctta
     2641 ccatactgca tattgtctcg gatcgttcca gagaacagaa ctgctttttg aggaacaaag
     2701 cccattaatt ctcgcaaatt atattgagtc atgtcactaa tgtccgttcc atttatttgg
     2761 atcgaaccag attcgatgtc atataatcga gggatcaaat tgactaaggt cgttttacct
     2821 gaaccagtcc cccctatgat tgcgacgatc tcgcccgact tggcttggaa atcaatatct
     2881 tccaatgcaa gtttttctgc tccatgatat cgataattga catgattgaa ggccaatgtt
     2941 gcgttttttc cagcaaaaga aactgtttta ggattttcag ggtcatggat accgattttt
     3001 tcatccaaca cttcattaat acggtcagct gaagcttgtg cacgaggcac catgataaaa
     3061 atagcggaaa gcatcataaa gctgatcaag atctgcatcg cataagtcat aaatgcaatc
     3121 agattaccga cttccaaagt catatctgct atgtagtgtc caccaaacca agtgattgct
     3181 acgtttgtac cgctcatgat caatgtcatc attggcatca tcaatgcgac gatcgtatta
     3241 actttgattg ccgtatttgt ataatcttta ttcgctaaat caaaacgatt ttcttcaaag
     3301 cgtgtcttat cgaatgctcg aatcactctg acccctgtca atccttctcg aaataccagg
     3361 tttaaacggt cagttttctt ttgcatactt ttgaataatg gaacagcaaa gtacatgatt
     3421 ccgccgatca aaataatcat tactgggatg acaactaaga agatttttgt caactgatga
     3481 tctttttgat aagcaagtat gctcgcgcca atcaacgtga ttggtgcatt gatcatcata
     3541 cgtaaaaaca tttgtgtaac catttggatt tgagtcacat cattggtcgt tcttgtgatc
     3601 aaagaggccg ttccatattt atcaaacgca tcttttgtca gactctctga ttttttatag
     3661 acatccgtac gcaattgctt acccagtttc tgtgattcac gagtagcaaa aaatgtattt
     3721 gcgatagcag ctaagatact gatcaaagaa aagccgatca tcacaaaacc tgtatgccaa
     3781 atataatcga catctccttg cgctacccct ttatcaataa tattggaggt aagtgtcggc
     3841 aaatataaat ctgccagtac ttggatcacc atgaaaactg cagctgcaat tgctgaagtc
     3901 aaggagatcc gttttacgat ttttagcatc tagttccctt ctttctattt atatactccg
     3961 tttttcagcc aagaaagttt caaattgaat tcactgattg cttgctctac tgagtaatct
     4021 tcagatgttg aaaataagcg atacgaatgc gcaattgttg taaatacagt attcatcact
     4081 aattggatca gtaattccaa ttcatgatca ttttttactt tcagcttcgt ccgatcgatc
     4141 aattcaagca actcttttgc atcttgtttg tgttctttat gtggatcgtg aggcgttttt
     4201 tggcgactcg tatgaggagc gacttttctt gaggcacggt aatccatgtt cataaacaag
     4261 ttacgataaa aagaagcatt ctcgccttcc aaaatctcat aaatcatttt agaaaaatag
     4321 gattcgaatc ctttgaatag atcaccatcg gattctttca ttagttgtaa catatcttta
     4381 gagctgtcac gtctcattgt ctcaaagtaa taaaaataaa gatcctcttt atcttcaaaa
     4441 tactgataga aactgcctct agggatatcc gctaatttga cgatattagc aatcgaagct
     4501 tcttttaagg gtactctaga aaactcgatt ctcgcagcct cgattagtct tttttgtttt
     4561 tctttaggca aatggaaaaa tgtctgtgtc ggcatatgga ttctcctttc tttcaagatg
     4621 acacattgtc atatgacgct atgtcattat aacacctcct acctgttttg caagacattt
     4681 gcatagtttt tttcattatc atccgataca ttaaaaaagt gataagagga atccttccat
     4741 ttgaattaat gagagttgcc cattaaaata gccacatact aaacaaagga tgagataaat
     4801 ggcccaatca attagtgtcc aagacttcaa taaattgcct ctcgatgctg acagcatcgt
     4861 tttagataca agaaatacct tagattacac aaaaaaccac ttaagccact cgctttctat
     4921 ccccgctgct atcttgccaa gacaattaaa aaatctagat ccaaagaaac tttattatat
     4981 tctaagctat acaggcaggc gatcagaagc attagccgat caacttactg ctaatggttt
     5041 tcgtgctgtt tatatcattg gtgggatgga agctcttcag tcgagtgttg cttgaatatt
     5101 gcttgttaga ttcaaaagag gctgtgacaa aaaatcgtgt cacagcctct tttataccct
     5161 gtcttttttt agttatttat tcttcaacct tatcaatatg acttgatagc cttttctttt
     5221 tcgagtaaac tgattttgtt agtcatagtt ataacaatca tagcaataaa aggagaaggt
     5281 aagcatatgg catctgtttt agtagtcaaa ggtcatcccc taactgcaga agaatcgcgc
     5341 acagttaagg cattgacgtc ttttttaaca agttataaag aaaatcatcc agatgatgaa
     5401 gtgactgttt tggaacttta tcgcgatgat attccggaaa tcgatgaaga attattatca
     5461 ggttgggaag cattacgtgc tggtgcagaa ttcacttcct tatcagaaag tcaacaacaa
     5521 aaaattgctc gtttcaatga attgactgat cagttccttg ctgctgataa aatcgttatc
     5581 gcaaacgcct tatggaatct aaatatccca acaaaattaa aagcttggtt cgataccgtc
     5641 aatgtagctg gaaaaacgtt ccgctataca gaaaacgggc cagaaggatt agtgacaggt
     5701 aaaaaagcac tgcacatcca atctaatggc ggtgtataca acggacaaga ctttgcctct
     5761 caatatgtaa aaggtatttt aaactttgta ggcatcgatc aagtagatca gctattcatc
     5821 gaaggaatcg attatgaccc tgaccgtgca gatgagttga tgcaaaatgc attagataaa
     5881 gctgctgctt taggtaaatc attttaaaaa ttgagataaa tgcatacaaa agagacagag
     5941 gaaaaaatct tcaaagcagc atttgtgcct tggatatttt cccatctgtc tctttttgtt
     6001 attctttctg ctttttcaac ggattttctt cataaagaga agagattgtt gtgtaccatt
     6061 caaaaacatg agtaatcact actttagctg ctgcataaac aggaatcccc aagatcacac
     6121 cgatgattcc gaacaatttc ccagaagtca gcagaactaa taaaatcgtt actggatgga
     6181 ttgctaactg attccctagt actaatggag agatcaagcg tccttctatt gtctgctcta
     6241 ctgcaaaaac gatcagtact ttgatgatca tgaatggacc tgctacaatg gctaaaaaga
     6301 tagccggaat catcgctaaa aatgatccta agtaagggat caggtttaaa aaacccgcaa
     6361 taatccccaa cgtgacagca tactctaaac caatgaccgc aaaaccaatc ataaacatga
     6421 ttgccacagc aaaagccaca gttagttgtc ctcttatata agaagaaact tgactattca
     6481 tttcactcag cacattcaac gtcggttttt gcatgcgtgt cggtaaaaat ttgacaaaat
     6541 aaggtgctaa ttgtttaccg tctttcaata gataaaataa gataaacggc atcgtcagca
     6601 gagccactaa aatagtcgct accgcgccga caaaacttcc aagactctga actgtactct
     6661 tagatatatc ttggatcata tcgcctgccg aattcatgaa cttatcacct gctgtttcca
     6721 actgttcgcg aaattggttg aacagcgggt cccgcaaaat ctcggttaat ttattatcaa
     6781 tcgtatctac atattgaggg aagttactga tgaagctcac tgtttgttcc tgaatcttag
     6841 ggatgatcac tacgctcccc catgcgatta gtgcaacaac caaaacaaac agcccaatga
     6901 tactgtaaag ccttggtact tttcgctttt caaagtaatc aactaccgga ttcatcaagt
     6961 aatacaagat tcctgctaaa atgataggca gacctacgat tgctaaaaat tgccagattg
     7021 gtgcaaacaa atatgaaact tttgtaaata aaaagacgat cagcaatatt aacaatacaa
     7081 caagtaaggc tgtgactact tgattattta aaaaccagcg ccaaaaccac gataccggtc
     7141 tgttcttctt attttttcct tccataattc ctcctgttag ttataaaaaa tttggcttcc
     7201 caaaccaata gcaggcagtc tatgcggatg aagatagatt ccatttgcaa tttgtccttc
     7261 ttctggacaa gcatcaaaaa tcaatgatac gtgagctact gtctttaaat tcccattggc
     7321 catcggaccg acataatcga tcgtatatac ctgatcatca aaagcaattg ttccgcctgc
     7381 tttcaaagaa aaaggttcgt cttttgatac ttcttgaatc accgaatatt ttcgtaaggc
     7441 agctgttgct gttttatcga acaaaatcag catgggttct tccttgttta ttgcttctgt
     7501 cccaatttct gtaatctttg cctgaatcat tgcactctct cctttaattg ctttcaaaaa
     7561 cagtataaca cattctcatt ctttagccgt gtggaataat tatgtgatag aataaaaacg
     7621 aaaactattt cattacaatt aggaggaatc agctcatatg atcgaaaaga taattttagg
     7681 aacctatacg cgtcgcgaaa gtaaaggaat ctatacgatc gaccttgata cagaaaaaga
     7741 agaattagcc aacctttcat tagctgttga agaaaatagc cctacctatg tagcaaaaag
     7801 taaagctggc aatctttaca cagttactag tgtggatgga ttaggtggtg ccggtgcgta
     7861 cgataaggat tttcattttt tgaatgcggt aacagagtct ggcgctcctt tgtgttatgt
     7921 agcggttgat gaagcacgtc aattactata cggggcgaac tatcataaag gtgaagtaaa
     7981 tgtctaccat atattaggag atggcgaact gaaagcagca gattcaatat tccatcaaga
     8041 agcgacaggt cctcataaaa accaagatca tgcgcatgtc cactatacgg atctgactcc
     8101 tgaccaacga ttagtcgtat gtgatcttgg tacagatcgt gtgtatactt atgatgtgtc
     8161 cgaaaacggc aaattgaatc ttgtaactac cttcactgca gagccaggaa caggccctcg
     8221 ccatcttgtc tttcatccaa atggacaatt cgcttattta tttggtgaat tagacagcac
     8281 agtccgcgtg ctttcttata ataaagaaac aggtgctttt gaagaattac agaaaatatc
     8341 gaccttgcca gaagaattcg acggtgaaaa tggaggggca gctatccgca tttcaaatga
     8401 tggcaagttc ctttatgctt ctaaccgagg acataactcg attgctgtat tcgcagtttt
     8461 tgaagatggt tcccacattc aaaacaagca aatcatctca acagaagggg attttccccg
     8521 cgatttcgca ctagatccaa gcaataattt tgtcgtgtgt gccaatcaga acaccgataa
     8581 tctgacatta tatcgccgtc atcctgaaac aggattactg gaattactga aaaaagatgt
     8641 ctatgtacca gaatgtgtct gtgtttattt tgatcgttag taagaaaagg agaatgaaat
     8701 gaatcagcaa gacgtattag acagactacg ggaagaacta aatattcctt tctttgatgg
     8761 gaaaatcgaa gataaagagt atagcgaaga ggaatatcag aaactcaaag ccgatttaca
     8821 gaactacttt gaacaatatg tacagaatgt agaaaactaa tcagctttcc atactatctg
     8881 aaaagaacat caggacaaga cttttccgtc tatcctgatg ttcttttcta caaataaaaa
     8941 accgccgaga tggttagact cgacggaaaa ggagtattta ctcgattttg agtaagtaca
     9001 aggttgttgt tggttatagg tatgtcatta tcataaagga ttttgatcac tctatcataa
     9061 aggtaatatt acatttatat tagataactc tagtttttat tgttatcaaa gatttctttt
     9121 attttttcaa caacaaatta gtcatttttt ggatggcagc tgtcaattgg tctgtcgctt
     9181 ggtcttgttt tgcttcagat gtattgaata gatcttcatc tacccctgat tcaagatcga
     9241 tactttggat catttcttca cagcctgcta catatgaaag ataagctttt tcaaaatttt
     9301 tatgaatgcc cattgctttt gctggtggac gcaaagtact gactttcata agcattgccc
     9361 gatatttttt tgttccttct tcaaataaca ggatgatctc ttcaagagtc gatttgtcca
     9421 gttcacttgt ttttccttca tcaattgcgt ttctgatcac ttcatatttc ggatgcattc
     9481 cttctccgat tgcttctgtt tccttgacga tttgatcgat ggactgcaca taatagccaa
     9541 tattcggtaa catgttcgtt ttcctacttt ctccattgtt gttattattt attctacttg
     9601 tttttatcct caaatgacaa gtacttgaaa aaatttaatg gtttctatac agctcgccat
     9661 tcttattcgt gctcaaagaa accatctgct aaactatatt gtttccctgc gacaatgtca
     9721 tattggatca attgatattc gtcgtaaatc tcttgttgcg agcgattgaa ttgcgcttct
     9781 ttataccact gtccgttttg atagtacagt tctcgttcaa acgccggaag ttcctgttct
     9841 aatgataaaa gcagctgata aaagccattt gttgtctgat tcgtctgttc cattagattc
     9901 gctgcaaaat aaaacggact ggtgattgca tcgtgagtcg tttgcttttc taattctcct
     9961 ttactgtcga acataagaaa ttgtgtttca tgcaatgttt gtttgtcatt ttttgcttgg
    10021 atcgtatctg aatagatccc tggaagatga tccccccaaa aaacaactaa agtccttcta
    10081 gaaagattct tcaattcttc cgtgaactgc ttcagtgccg tgctgctata ggaaatatct
    10141 tgcagataat tctctaagtc aagtgtccca cttccatctg aagtttttgc aggatagtct
    10201 agattatcat actttccatc gtagggcata tgtgtctgca tcgtgactaa atgaatgaac
    10261 tgaggtgttt tttcttcctt gagaagtgtc attacttctt tgtaagctga ctcatcagaa
    10321 atatatggat tattctctat cgtatccgta taggtcatcg tacgctcgct gatgaactgg
    10381 tcaaatccta atgtctgata aacatcctct cttttataca tcgaagtatt gtatggatgg
    10441 atcgctgtcg tctggtatga ttgtgcgttt aacgctgaaa cgatagaagg aagctgatcc
    10501 atttttggta caagcatcgt gtaaggggtg gtgagttgcg cattaaataa cgccatagaa
    10561 aaaccagtca atgcttcaaa ttcgatattt gctgttccac cgccatagtt ttgagaaagc
    10621 atattgccac tatatgtttg atcagctact tcataataat ctgccaatgg ctcaccagat
    10681 acttctacgc cgtttaatcg actaggatct gagaaacttt cactcatcac gaacacgatg
    10741 ttcggcgact cttcctctac agttttattt ttttcatcgg ctagcttctg gtatttttca
    10801 gtgatttctt tgatcttttc tttcgaatat ccttcaggtt catccattgg ttctaccttc
    10861 agattgtaca aaaacccacc gataaaacca gtgttatagt agttcatttt ctggctgtaa
    10921 ggtatccata gtgccgtttt attatatgct tttcgcaaca aattatcggg attgttgaaa
    10981 ttactgatat accctagcag tccaattgcc acaagcagtg tcgttaatcg gatcaattgg
    11041 aatcgccttc cttttttcag gcttcgaaac atgtaccagc aaaacaatcc tatcacggtt
    11101 cctgcggcag ctaagatcac tgtaaacagc atagtgccgg tcatatcttt cagcaatccg
    11161 atttcagtga tcatcttcaa atcgtctgga taaatcggtt cttgccgata actcattttc
    11221 atataatttg caaaacctaa tacaccgatg gctacgacat acgtaaggga acctaaaggg
    11281 acagatcctg ctagtgcaat cagaaaaata agaataatca gcaagacgag acaggctaag
    11341 aagaattttt ccgtatgcca agaaaaagca aatttcaacg caaggtctac ggatagatca
    11401 ttttgacacc actgcaaaaa taaattacta aaaacaacaa gaaaaaagat actgatgatt
    11461 gctgctgttc cttttaaaat ctttttctgt ttggtcgaaa gtctgcttat atatcttttc
    11521 aaatgcttgc tccttcattt ctatcaataa aagaatgttg cttctcttat tttagttgta
    11581 cgaaattcga aagtaaagaa cggaaagaag aattaatgaa atccaaatat tctctttctt
    11641 tatggccttt ctggtttctt taataagcgg acctttcgta ctccagaaat tttttctagc
    11701 tgttgtttca cttgattgag ctgttcaaaa tcagtactgt ctatgtcaat caatatgtag
    11761 acatgctcat tcttatggtt acgcgatata tctgcgatcg ctagctcgtt ctcattcagc
    11821 agagaaaata tctctgctaa tatattggtt ttcttttgat aaaatatagt gaatcgaaac
    11881 ggcgcttgga aaaacattcg tgcggatgga taattgaccg cttctctaac cgtaccgaac
    11941 aaaagataat cttttaaggc ttcaactgcc aaacgtccgc tgtctgccaa agcttcctga
    12001 gtcgatcccc ctagatgagg caacataagt atacggtcat tttctaagaa ctcttcttct
    12061 ggaaaatcag tcaagtattt agccagatgt tgtttttcca atgcttgcat aacagcatat
    12121 ttatcaacaa tttcacttct tcctacattg ataagtacag catctttttt cattttttct
    12181 atattcgcct gatcgatcaa tccttttgta tcttctgtca acggcagcat gactacgatg
    12241 taatccgagg tagaaagaac tgtttctaaa tctgcttgcc gaacataatc caactgggca
    12301 tcgcggatag aataacccaa gacatccatc cctaagctat agcaacttag cgctactttt
    12361 gtgcctatcg ctccaagacc aagaagaccg atggttttgc cttgcaattc tcgtcccaca
    12421 taagcacttc ttttgttttc tgcctgttct aaaatattag gacctgttag tgtttgtacc
    12481 atacgacttg cttcgattat cggacgggaa gataagagca aacagcacaa aacaagctct
    12541 tttactgcat tagcatttac acctggtgta ttcatgacga tcgtcccgtt ttcagaagct
    12601 ttttcaacgt tgatcgtgtt caccccaaca ccagctcttg aaattgctag caaatctggt
    12661 gtaagccatt catctttcac tttcgtacta cgaataacta ttccttcggc tggcaaatca
    12721 tctattattt tgaaatattc cccttgtaac ttttctatct cttgttctgg aatagcatca
    12781 atcaaatgaa cgtgatacat aaaaccccct ccttactaac aagtatctcg aaatttctgc
    12841 aattagacaa ctgtttacca tttgacttcc tagaagcaaa aagagcagtt agagcagagt
    12901 aggctgagtg ataaaaataa ggctatgaca agttactgcc ataagcctta ttttcgagag
    12961 caaaatattg agggtgagat atcttgataa atggtgttcc gttagctgac attgataata
    13021 agactaaatt tcaaaaaagt tgaaaagcaa atttcgtcaa tctcttctta tttcttaaaa
    13081 ctaagtggct ttttcacaac ctctttttat ctaataacca ctgtttccaa ctcaactaat
    13141 tttgcccacg tttcaatttg atctgttgtt agatttagcg agacaacggt atgatgaccg
    13201 ccacctgcct gaatccatga atggacacct tcatggaaat tcggtttagt tttccataac
    13261 acacgtgcaa caggtaaatt aggtgcttca gtcgttggtt caaaggcttc tacttcattg
    13321 atcagcagtt tataatgcgt accgaaatct gccatcgata cgactacccc ttctcctgct
    13381 ttcccatcaa atacaagacg cgccggatct tctctatctc ccattgataa aggagaaaca
    13441 acgattcttg gtttcgtcgc agcaagcgtc ggatctactt ccatcatatg ggattccaag
    13501 attgcttctt ggccactagc tagctcgtaa gtataatctt ccatgaatcc tgtatctttc
    13561 cctcgagcca tgattttcag caaccgatca atcgctgcag ttttccagtc gccttcccca
    13621 gcaaaaccgt atccttctgc catcaaacgt tgtacagcta gtccaggtag ttgtttcatt
    13681 ccatacaggt cttcaaaatt agtcgtaaaa gcgttatagc ctccttcttc taagaaacgg
    13741 cgaataccga tttcctgctg agcttgtact tttacatgtt cctcccatgt cttttcttca
    13801 taatcaccat agtcgaaggt atacaattcc ttgtactctt caaataattg atcgacttct
    13861 tcgtctgata cgcgatcgat tacttgtaca agatctccga taccaaaata atcaacagtc
    13921 caaccaaatt gaatctgtgc ttccactttg tctccttctg tgacacccac gtttctcatg
    13981 ttgtcaccaa aacgagccac ttttattcca aaactttcat tataggctac tgcaacatcc
    14041 atccaatcag caatctcttt ttggatctca ggtcgtttcc agtagccaac gacgatttta
    14101 ttttgtttat ttaatcgagc attgatgaac ccatattcgc ggtcaccatg agcggattga
    14161 tttaaattca tgaaatccat atcgatcgtt ttccaaggaa tgctttcgtt atattgcgta
    14221 gctaaatgaa gcaatggttt ttgtagaagc tttgtcccgc ggatccacat ttttgctggt
    14281 gagaaagtat gcatccaagt gatcacacct gctacttctt ctcgataatt gacctctttc
    14341 atgatttttg tgatcgtatc agcagtaact gctaattctt gaaggcggat tggataaggc
    14401 aattggccat tttcattcag ttcatcgacc atttcttgtg catgtttctt tacttctcgc
    14461 agtgcttctt ccccatataa atgctgtgat cctacaacaa accaaaattc tttttctcca
    14521 atattcaaca taattagcca ctccttttat ttgttttgtc cgtaatacgc attttttccg
    14581 tgttttcgta aataatgttt atctaaaatc cgttgaggca gctcttctga aaatgaattg
    14641 agctgtctgg taaataaatt catcttgcat acttcatcta gtacgactgc gttcattacc
    14701 gcactttgcg catctttccc ccaagtaaat ggaccgtgtc cgtgtaaaag tacccctgga
    14761 attgctaagg gatcaatttt gcgttctttg aatgtttcta tgataacttt tcctgtttca
    14821 tattcgtacc cgctgtcgat ttcctgttgt gtcaaaaatc gagcacaagg taccgatcca
    14881 taaaaagtat ctgcatgcgt cgtccccatc gcaggaacat ccaatcctgc ttgtgcccag
    14941 atcgtcgccc atgtcgagtg agtatggacg attcctccga tttgaggaaa tgaacgatat
    15001 aaaacagcat gagtaggcgt atccgaagag ggattgagtt taccttcaat gatatgattg
    15061 tccaagtcca caacgaccat gtcgtctgct gtcatctctt cataactgac tccgctaggt
    15121 ttgataacga aatatcgtgt ttcaggatca aaagcgctca catttcccca tgtatatttg
    15181 acgagtccgt gtttaggcaa gtcaagattt gcttggtata cttcttcttt cagttgttcc
    15241 agcattttct atcactcctt tttcttgcaa ttgatgaatc gctgtttttt caatgtcgat
    15301 cccctcacgg taacgtctca taaatatctg atagcctgct atttcttctg ctgaaggtgt
    15361 gatggtgatt ccttggtctt gtccaaacac gtcttctgcc aagaagtttt ctaaagactt
    15421 cccatgtcga tccatcatat aggctgctaa taacgcgatt ccccacgctc caccttctcc
    15481 ggctgtgtcc atcactgtaa ctggtgcctc catagcagat gctagaatcc gctgtccaac
    15541 ttctggtgtt ttaaaaatcc ccccatgccc cactaaacga tcaatttgga cattctcaga
    15601 tttcaatata tccattccga ttctcattgc accaaaagca ctggctaaat ggatccgcat
    15661 gaaattcgct aaatcaaaac ggctacctgg tgtacgtaca aataatggcc ttccttcatt
    15721 tactcctgta atgttttcac cggaaaaata accataagaa agtaatcccc cgcaatccgt
    15781 atcgccttct agcgctttgt tgaataatac cgtgaataat ttatctctgc ttatctccat
    15841 acccaaagaa ttggtaaatt cttcaaaaat actgacccaa gcattgatat ccgaagagca
    15901 gttattcgta tgaaccatgc ctactagttc tcctgaaggt gtagtgacca tgtcgatttc
    15961 cggatggaca ttttctagtt ctttttctaa tacgatcata gcgaaggcgg aagtaccagc
    16021 cgaaatgttc cctgtccctt tggctacact gttcgtagcg accataccgg ttcctgcatc
    16081 cccttctggc ggacaaaccg ggattcctgg tctcaaattt cccgtagggt cgatcagata
    16141 agcccctgat tcgcttaact tgccagcttc ttctcctgct actagaactt taggcaaaat
    16201 gtgatccaag tcaatcgcta cgtgcgcttt ttcgattaac tgaccaaaaa tatttttcat
    16261 ttcttgatgg taggttttcg ttgaaggatc gataggaaac atgcctgatg catctcctac
    16321 gcctagtact ttctcaccag taagctgcca atggacataa cctgcaagcg ttgtcaaaaa
    16381 attaatttct ttcacatgtt cttctttatt caaaatagat tgatacaaat gagcgatact
    16441 ccatctctgc ggaatattgt attgaaattt ttccgttaat attcgttctg cttcttcagt
    16501 gattgtattt cgccaagtac gaaatggtac tagtaactgt tccttgctat caaatgctag
    16561 ataaccgtgc atcattgcac tgaacccaat cgacccgatt gtcgtaagat tctcgccata
    16621 gatttcgaat acttctgctg ccatttttcg gtaactgacg cgcagtcctt tccaaatatc
    16681 ttctaatgaa taggtccaga taccattttc tagtttgttt tcccactcat aactaccagc
    16741 ggcaatagga gtaaaagatg aatcaatcaa tacagctttg atcctagttg atccaaactc
    16801 aatccctaaa gatgtacgac catctatgac atctaacata ctttgcgcat ttacttcctt
    16861 cataatgatt taactccctc cttctcgtca aacctgatca aaccgtcttt ttagtagcgc
    16921 ttacaatgat tattgtatac ttttgtacgt acatgtcaag cagttattta caagaataca
    16981 ataaaaaaca cttgttttgt acgtacataa gttataaaat gaaattgctt acaaaatctg
    17041 atcaaccgcc ttctcgaaat tctagaagga gagaatactt atgaaaaaag aaaaaaaagt
    17101 ttcctcatcg tttatttatt tttttggcgc atttggcggc attctatttg gatatgatat
    17161 tggtgttatg accggcgcct tacctttttt acagcatgat tggggtttgg caggtaaagc
    17221 ttctttgata ggatggatca cgtcttcggt catgttaggt gcgatccttg gcggctcttt
    17281 atctggtctt ctttctgata agcttggacg acgaaaaatg attcttcttt ctgcacttat
    17341 ttttatggct ggttctgtcc tttctgcatc tgcccctcac aatggttctt attttctgat
    17401 tgcagcaagg attcttctag gtttagctgt tggcgctgca tctgccctag ttcctgctta
    17461 tatgtctgaa atggctcctg ctagactaag gggaagattg tcagggatca atcaagtgat
    17521 gattgcttct ggcatgctcc tttcctatgt tgcagattat ttgctaaaag ggttgcctga
    17581 aacgatggct tggcgcgtga tgttagggct cgctgctgtc cccgcgctga ttttattttt
    17641 cggtgtttta gctctaccag agtcaccgcg ttttcttatg caatctggcc gcttggaaga
    17701 ggcaaaaaga gtattgaact atattcggac accaaaagaa gctgaacagg aattcgaaca
    17761 aatccagctg aatgtcaaac aagaaaagac aaccggaact tcttggcata ctttgttttt
    17821 agaaaaatat cgttccttag tcattgccgg tattggtgta gcagtattcc agcaatttca
    17881 aggagctaat gctatttttt actatattcc gctgatcgta gaaaaagcga ctgggcatgc
    17941 agcgagcgat gcattgatgt ggccgatcat ccaaggaatc attttagttg ctggttcttt
    18001 gctctttttg gttattgcag acaagttcaa tcggcgaact ttattgaaaa taggcggtag
    18061 cgtgatggga ctttctttca tcctaccagc tgttttagga actgtactgg atgctcatac
    18121 aaattcgttg ttgattctct tgtttttatg tatttatgtc gcattttatt cttgcacatg
    18181 ggctccactg acatgggtaa tcgtaggcga aatattccca ctagctgtcc gcgggcgagc
    18241 atctggccta gcctcttctt ttaattggat tggttctttc ctagttggct tgctttttcc
    18301 tgtgatgact gcttctatgt ctcaagaaat cgttttcggc atttttggga tcatctgctt
    18361 tttaggggtt ttatttattc aagagatcgt accagaaact cgtgggaaat ctttagagga
    18421 aatcgaacaa agtgcatcta aaaaaactta tcctaaacgt atttctatcc atcattctta
    18481 aagaggttgt gacagaagtg gtcagcttca agaaataaga aggaaccgct tagtttccag
    18541 tcacaaggaa caatttcaaa aaacagcttc tcatgtttga tgaatattgt gacttgtgac
    18601 cagttggtag gagaacaccg tttagtggag aggtggtgaa agaaacgttc agccttgagc
    18661 gatgacaaaa gctctcacaa acattgcgac gagtaaccgt aggagcaata agaggcggta
    18721 aaaacccgtc tcttattttt cgttttcttt cactgtttcc cgttcaacta gtacaggttc
    18781 atagagaata tttggctgtg cctgtccttt ttcaatcgtt gtgacgatcc accgtgcggc
    18841 atcttgtccc aacttttctt ttggatgcgt caatgttgtc aattttttat tccctaaatg
    18901 gcttaaagaa gaatcgtctg ttcctacgat cgataggtca tctggaatat gatagccatt
    18961 ttctgtcaac ttatctagca ttaaactagc tatttgatcg ttatagcaaa tgatgccatc
    19021 taaagcttgt tcttctttca accgttgtac tgttttttca gcgattgttt ctcgtgtttc
    19081 cgtggtgaaa gtaatgatat cttccgtcaa aaaacgcaca ttatactgtt cacacgcgct
    19141 gataaaacct ttcatcctgt attttccttg aagatcgtcg atttttgtga tgaacaacag
    19201 acgctgatgt ccttttttta tcaaatattc tgctgccata aaaccgactt tcacatcatc
    19261 taaacaaata taagaggcat ttaactcttc ataagcagca ttgatcatca ccatcggaat
    19321 gccttgttct ctcaaagcaa cataaagtgc taagtttggg ttatactgat tacttttcgt
    19381 aggctcaacg atcaaaccat ctaccccata agcaatcatt ttcttcaaac actctttctc
    19441 caattcgtga tcgttattcg tactggctaa aagcaatgaa tacccagatt ctcgtaattc
    19501 attttcgatt cctcggataa tcgacggaaa aatataatca gagagatatg tggtgatgac
    19561 accgatcgtt tttgttctgt tcaatggtgt tttttctttc ttatagctgt catctacata
    19621 tgtgcccgac cctttttctt tacgcagata gccctcattt accaacacag cgattgcttg
    19681 ccgaatcgta tgtctgctga cgtcatatat ttcttgcagc ttgaattctg agggaatggt
    19741 tgtatttact tcgtattcct cacgaaggat cttttgtttt atctcttctg caatatcttg
    19801 atattttgcc atttgccttg ccccttttta tttgtacgta catatatcat aacgagtctg
    19861 caaggtttat tcaagcaaaa atcaaggttt cttgtgctca taaggcatac ggaacaggtt
    19921 caccaaattc tggaaatcct tgctcattcc acgtaaagca ttgcgcgttc gcgtgccgat
    19981 taggattgtc taacggatcc cctttttggt tcttctctgg tcgagcatga tagatcaaaa
    20041 tatcaaagca cccgtcttct gaaaccgtaa acgagttgtg accaggacca aattgcttat
    20101 ttttttcaga agaaacgaat actggctccg ataatttatg ccatgattct tttaataaaa
    20161 gattcttgtg ctcatcagcc cacagcaggc ccatggcata gttttcatct gttgcactac
    20221 cagaatacgt aatgaatatt ttcccattgc gagtaaggac tgctggacct tcatttactg
    20281 aaaaaccccg tttttcccat tcatactcag gtatagaaag gaggatctgc ttccccttta
    20341 acgtccaagg attatccatt tcggatagat aaagattaga attcccagta atttcaggat
    20401 cttgttgggc ccacacataa tatagctttc cttgagaaga gaaagttgtt ccgtctaaac
    20461 tgaaagtttc ccttttcgtt tttatttgtc ccttttctat ccaatctgta ttcattggat
    20521 ctatatgctg attttcaagt acgaacatgc ggtgatgatg agattcatca cgtatagttt
    20581 tatgattgct tgcagcaaag taaatatacc attttccatt gatataatgg acttcaggtg
    20641 cccagatcaa ttcactcatc ggtccttctt catgagcctg ccatacaatc aggcttgcag
    20701 catgttctaa ttcattcagt gactttgccc ttcttaattc aatcacttgg tagcctggaa
    20761 ccgatcctgt aaaataataa taaccatctg tatgtttata tacccaagga tctgcccgtt
    20821 gccgaacgat aggattatta taaagtgtct tcatcataac aaatttcctc acattttctt
    20881 tattctaatt acattccaag agtatttttc tatccctaca tttaattcgt catgtttttc
    20941 tattgaaaaa tagtttattt caggttttat tttttctggt tcttcacgtg tatttttgtc
    21001 caacagatcg ctactggtta atgtgtagtg ctctccttga tctagcaaat tgaaatcatg
    21061 ttcaatcgtt atcttttgtt gttcatttgt gcgattgatc aagaaaatag tcagctgatt
    21121 gccgttatct acgatcacac tgtccacata aggaacattt tttatctttt cacaatcata
    21181 aacagggcaa atgatttgtt gtttcaatac ttgaccttta gcatatttcg ataagtgttg
    21241 catcacataa taagttggat tcctccatgc ttgtccttta gcatctgtca gtattaaagg
    21301 tattgtgttt actaacaatg attgacaact aatctttacg cgatctgcgt gtcgtaaaat
    21361 agccagccct aatgaaccaa ataataatgt atcttccata gtaaagtaac accaatcgat
    21421 gggactaccg acttcaaaat ccctatgtct tttttccggt tgggcatgta cattccattc
    21481 atcaaacgct agatacattg ttttctcact tctcaaatat ccttttacat aatcacaagt
    21541 agcaacgatt tcttcaattt gacgatcgaa tcgataagct tttgcaaggt atgtcgctgt
    21601 atcatcacgc tcatttttag gaggtttagt caagtcttct tcatcatact tatcaatata
    21661 gttatgcaaa gctaaataat ctacattctc ataagcttct tctaatgcga tacgatccca
    21721 ttcagggtac gatggtaaac gtggcgtaga gcttccaact aagattgttt caattgaatc
    21781 atccactaac ttcatgactt ttgaggcttc atttgctaac ctaccatatt cataagcact
    21841 cttagccccc acttgccatg gaccgtctag ctcattccct aaacaccata atttaacgcc
    21901 aaaaggcttt ttttgcccat tttttattct taaatcactc cagaaggttc cttttggaaa
    21961 attacaatat tctactaaat tttttgcttc atcaattcct tttgttccta aattcaccgt
    22021 gaatatcggt ttcgcttgta catgactgat ccatttaaaa aattcgtgga gtccaaaaga
    22081 atttggttct atacctcgcc atgctaaatc aatttttttt ggtcgttgtt ctttcctacc
    22141 tacagtatcc acccaatcat aaccagatgt aaagtttcct ccaggatagc gaatgacacc
    22201 taattctaat tcctttacat aagagaggac atcttgtcta aacccgtcac catcagctgt
    22261 ttcatggccc ggttcataaa tccctgtata gacgacactt cccatatgct caacaaatga
    22321 gccaaacagc cgagaactga tctctcctac cgtaaaatcc tctctgattt ttactttcac
    22381 ttcttcgtcc aacagctttc cctacctttc atttcctata gtcaagataa tagatacaag
    22441 tttccatacg ccaccagcaa agataaaaat aaaaggaggg aaaagaaata tgagcagtac
    22501 aaatcctaat aacaatacgc aacaaagaat atttctcaaa aaatcaaaaa atactttcca
    22561 tgcactttgt tcaaaaattt gtaaaaatgt gatatctttg ttttcagaaa tcacatatat
    22621 ccaggataaa agaaacatgg aataaataag taaaactaca tatccactaa ttgaaagtac
    22681 gattgtctgt tcttctaata attgattaac aagaaaataa ataatgatcg ttaacagact
    22741 aaggaacaag ttcttaccaa aatgttgctt tattccttga aagaaaaaat aaatgatatt
    22801 tcctgatccc tcacctttcc attgcgccat tacataaaaa aacagcacat gtagcaggca
    22861 cgatagtaat aacaggcaaa cacacgatta cccagagaat acctaataag atgtaatcag
    22921 aaaccacaat caactgtcca taaagtttag tctcaactat tttcatcttc ctcactcttt
    22981 cattccagac atagctgttc cttgaacaaa atatttctgt gcaaaaatat aaaccactag
    23041 taatggcagc attgaaataa ccgttccagc cattacaggt ccataaaaag aaatgttctg
    23101 ccctgtaaat aaagctaacc ctgctggtaa agttctcatt tttgaactac ttgtcaatat
    23161 caatggataa agcaagtcat tccaactatt catcagcgtg aaaatcccta atgataaaag
    23221 agtaggtttg ctcaatggca acatgatttt caaaaaaata ttaaactcac ttaatccatc
    23281 aatgcgtgct gcctcttcca aagaatctgg taaagtaata aaaaaggaac gcatcatgaa
    23341 gataccaaat gcagttgtca tacgaggaat gatcaaacct gcataagtat caagcatgcc
    23401 aagcaaattg acttcaataa atagaggaat catgaagact tggaatggga tcatcattgt
    23461 cagcaaaacg aaatagaaca aaactgattt tcctttgaaa cgcatacgag caaatgcata
    23521 ccccgcaaga gaatcaaaga atacagaagt gatcactgtc cctccagcaa aaatcactgt
    23581 atttttgatg taatctaata aagggatcgt tgtccaaacc ttaatatagt tatctagggt
    23641 atagctatct gcaaatattc taggcggaaa tgagataatg tctttttcgt gtttaaaaga
    23701 agaaataatc agccacaaaa aaggaaacgc aataaccaac aatataacta gcatactaat
    23761 cgttcgaatg atttttttac cactaactgc ttttcgacta ttcacagtaa ctgtaatcga
    23821 gctttctggt gccatacagg tttccctcct atttcatttg tttttctttc cgtgacatgt
    23881 acacattagt ggagatagct atagttgcaa caatgataaa caaaaccgaa gacagtgctg
    23941 atgcatagcc caattcataa ggtgctgtaa atcctcgact gtaaatatat tgaacagctg
    24001 tttctgtctt aaattgtggg ccaccagcgg ttgcaacata tacttggtca aacacttgca
    24061 tcgaaccaat cagattcgtt aaaatacaaa aacctaagga gggaacgatc tgaggtagcg
    24121 taatgttaaa aaactgctgt cgatttgttg caccatccat ttgagcagat tcatacaaag
    24181 agggagagat tccctgaata gcagtcaaga gaatcgtcat agtaacacca aaattcttcc
    24241 aaacagtcat gatggctacc gtcggcatag caagggttgg atcgcgaaaa aattgaggga
    24301 tcggcaagcc gacttgtgaa aacaagtaag gaatcgcccc tacattcgga tcaagcaaca
    24361 tagaaaaaat aatcgcaatt gacgtcaatg aacaaataac tggaatgtaa aatgtcgaac
    24421 gacaaaaacg attgaatctg gtatttttag ataatgctac tgctgctaat aaaccaacga
    24481 taatttgtgt tggcgtttcg agtacggtga aatataaaga atgaatcaac gaattaactg
    24541 ctcgttcatc actaaatata cgtgtgaaat tttcaaaact tacaaaattt cttgatgtaa
    24601 agaaaatatt caaatctgta aaactaatag caaatgttcc taaaagcggt atgacagtaa
    24661 ataataataa aactaaaaaa gatggagtta aaaacaaata cgcagcacga tcaggacgat
    24721 tccaatattt ggtgaatccg ttcatatagt ccacctcatc tttcattttg ataaaatata
    24781 caatcttggt ttaaacgaat ctgaataaga tatccgaaca atcgctgtga tttttgcaat
    24841 aacacctatc tgcaaatact aggtcgatca ttcagatatc tgtatcttgc caacagtcta
    24901 tcctgtataa agttctgtac tatttttgca gtaattgatt gatggcatca tctgcatcgt
    24961 tcatgagtgt ctcaggatct tctcctgcta ataatttttc aatcagtgga ttgatgatat
    25021 cgttattgat cgcagagatt tgggtaaaac ctggtaaata tggctctgca tagtccattt
    25081 gtttcgataa ttcagataca ataggatcat tttttacttc ttcatctttt gctactgaat
    25141 ccaagtaggc aggaaaacca ttttcgatac tccatttttt accaatttca gttgtattcc
    25201 aatatttcaa aaactcatag acagcttctt ttttattatt atctgtactt gccggaatgg
    25261 catatcctac gccatctaaa atagctgttt ttttgtctga atcactccct tgtggtaagg
    25321 tagtcacatt ataatcaatc tcgtttgctt tcaatccgtt atttaaccat ggcccattga
    25381 tttcaatggc tagttgacca gcattcatta aattgtccat ttcggcgcca gaaatcgatt
    25441 ctggaccagt cttgtctaca tggatcattt tttggatcgc ttttaacgtt ttaaggttct
    25501 caggagacgc aaattcagac ttagtataat catcgttcac taatttaccg ccatttgcta
    25561 acatccagtt atataacggt gcagttccat ccttattgaa gacaaaacct gatacatttt
    25621 tactactatc agttaatttt ggtgccattt ctgtcaattc ttcccaagta gtaggtggtt
    25681 gttcagtatc taatccagct tgtttaaaca aatcattatt ccaatacata tacatgcctt
    25741 gtacctgcat ggggacaaaa tactgtttac cttctacttc acctaattca atagccgttt
    25801 ctttaaaatc agatttatct actccatcat attcccagaa atcgtctaat ggttgtaccg
    25861 ctccgttttc tacatactgt gcaaaatctg gataatttaa tgcaataaag tcaggtgctt
    25921 ttttagaaga aatcgctgta ggaagttttt cattcaaatt ggcccaagtc atgatatcca
    25981 tttcaatttt gatgttttta tcatttgttt tattaaattc attaacgatt tcttgcaata
    26041 tttcaccatc agatgcagta aacccattcc aaaaagtcaa agtcacttct ttatcagaat
    26101 cagattctgc tgaacttccg ccaccgcaag ctcctaaaat acctgttgca gctaccaaca
    26161 aagagccaat taaccatttt ttacctttca ttttttgttc ctccttcatc tgataaacga
    26221 catctgacca cattccaaga tagcggtttc aataaacaat tgattttccc atcttcagct
    26281 tttacatttg ttgaatgact tggttttact tgttcacttt taggaagatt agttgctttt
    26341 gtatcaaatc cactcatttc agaaaaatca atcactccct ctaatgataa ttcagacaag
    26401 tgaacagtta gattcatttc ttcttctcca cggttaactg caaatatgac aagttctttg
    26461 tcatttatta cggctatact ttctaaatac ggcacttctt caaaatcttc cgtcgcatag
    26521 tttgctgaac gaatttgtgg gcttaacacc tctccttgtc catacacagc agcttgcata
    26581 aatggataat agatcgtctg tctccaagct tctccgtttg tttctgtcct gattggtgca
    26641 ataacattta ccaattgagc aagacaagca atctttactc tatctgcatg tttcaataaa
    26701 gtgattaata gacagcctaa tagtaatgca tcttcaaaat tatagttatc ttctagtaaa
    26761 ggaggagcaa tctgccaagg cgctgcttgc tcatcttgtt ccgctgaatg ataccaaata
    26821 ttccattcat caaaggacag gttgatctgc ttcttactat gtttcttcgc cttgactgta
    26881 tcgcacatcg ctgtcacttc agaaatgaac cgatccatgt ctaaggaacg tgcaagataa
    26941 tgagaaagat catttttttg gttgccataa tattgatgca gagacaaata atctatttga
    27001 tcgtacgctt gatcaagaac tgttaactcc caatcaccaa atgtaggcat ttgccgattc
    27061 gaacttccgc ataaaaccac ctcaattgaa tcatctacga gtttcatcgc cttagccgtt
    27121 tcctctgcta accgtccata ttcttccgct gttttatgtc caatctgcca aggaccgtcc
    27181 atttcattcc ctaaacacca tgtcttaatt ccaaaagggc tctcttgacc attcgaacgc
    27241 cttaaatcac tccaataagt tcctttagga aaattacaat attcgactaa attacgagct
    27301 gcatctactc cacgagtacc cagattgaca gccatattga tttcggcccc cacatgctga
    27361 caccagttat aaaattcatg aatcccaact tcattcgttt caattgtccg ccaagctaaa
    27421 tccaaccttc taggtctatt tgctatgggc ccaatactgt cttcccaacg aaatcctgac
    27481 acaaaatttc caccaggata tctaatcatg ggaatgttca attcttttac caagtgaatg
    27541 acgtcttggc gaaatccact tttattagct gatggatgat ctggctgata aatcccttca
    27601 tatactgctc gtcccatatg ttcaataaat gaactgtaca accgcggatc aactttgcct
    27661 acacgcttga cactactaat caacattgtg gcttccataa ctgacctcct ttaatttata
    27721 catgaataat acacctcgtt gaaagcgttg tcaataatat aaatgttaaa cttacttatt
    27781 ttttatcgat tttaattaac caaaatatta ataatgatta aaacaaataa tttaatataa
    27841 cttttattaa caaatatgtt aatatataag aaaaaccttt taagaggtga tatatatgca
    27901 actacaaata aacgaagaat ccttaccggt atatgaagca ttagctagta aaacaaggat
    27961 caagatcatc cagctacttt ccaaaaaaaa gatgaatgtc aaagatttgg caaaagaact
    28021 tggagtgagc agtgctatca cgacgatgca cgtgaaaaag ctagaggaag caaacatcat
    28081 caaaacagaa aaagtaggac aacaaaaaat ttcgagcctt cgtgtcgata aaatcgatat
    28141 cagttttcca gaaaaaatat tcaatgcttt tgatacgaaa gaaacatcga tacctattgg
    28201 tcactataca aattatgcaa ttgaaccaac atgcggttta gctacgatcc atgattttat
    28261 cgggaaagtg gatgaaccac gctattttat ggatcctcga aggatggatg cccgcattct
    28321 ctggtttacc agcggatttg tcgagtatca ggcacctaat tttttaaata cagaggatac
    28381 attggagatg ttggaagttt ctgtggaaat ttcttctgaa tttccttttt caaatgacaa
    28441 ttggccttca gatatcactt tcagcctaaa tggtgtggag ctaggaacat ggacgagccc
    28501 tggagatttt gctgatatcc gcggtaaata tacgcctgat tggtatccag ataatcttaa
    28561 tcaatacggc ttgctgaaga cgatccgaat taccaaacac ttgacgaata tgaatggaga
    28621 acccttgtca aacatcacga tcaacgacat ccctaaagag caagacactt ggcatttgcg
    28681 aatcgaagtg aaagacgatg ccaaacatgt ggggggctgt actttatttg gtaaaggatt
    28741 cggtaattac gatcaggata tcaaattaaa agtttactac agctgatatt tttcttttct
    28801 attttataaa acaaaaacag ccaatcccta tgaagggacg gctgtttttg ctttattgtt
    28861 atttccagaa atcatccaaa acggaaattg gcaaatgtcg tttatgttgt gtcttgttcc
    28921 accatgcttc gattttttct tgtgcttgag cgggaacttc ttttccttct agataatcat
    28981 caatttcatt atatgtgaca cctagtgcga cttcatctgc aatcattggt ttcccatctt
    29041 caagatctgc agtcggaatt tttgtgtata atttttccgg tgcattcaat gcttgaagca
    29101 attgtttccc ttgtcgtttg tccaaacgga ataatggcaa aatgtcggct ccaccatcac
    29161 caaatttcgt gaagaatcca gtaatgtttt ctgcagcatg atctgtccct aatacggctc
    29221 ctgctctttc tccagctacg gcatattgcg taatcatacg ttgacgtgct ttgatatttc
    29281 ctttgttaaa atcgctgatt cccacacctg cttcgcttaa tacttgtact tgtgcatcaa
    29341 cagctggttt gatatttact cgcagactaa catcgggctg gataaagtca agagcagctt
    29401 ttgcatcttc ttcatctgct tgttcaccat aaggaagacg aacagcgata aattgatagt
    29461 tttcatcttt tgtttcttca cgcatttctt ccatcgttag ttgcgccaaa cggcctgcta
    29521 aagtagaatc ttggccgccg ctgataccta gtacaaaagt tttaagaaac ggatattttt
    29581 tcaaatatgc tttcataaag tcaatacttt tacgtatttc ttcttttgga tcaattgttg
    29641 gtttgacacc taattcattg ataatttctg tctgcaggct catttattct cctcctatgc
    29701 ttctgtatga agttctgcta cgcttttttt cattcgttcc atgatagcca ttttatggtt
    29761 ccagcattca gtagacagat cgactgggta tttttgcgga ttcaagtctc gtttatactc
    29821 ttcccatagt gaatctagat tttcttttgt atattctttg atttcgttta gtgcaggtaa
    29881 ttcgtaaact ctttttcctt cgataaagat atcttgtaaa actgggcgag ctgtaaagtc
    29941 tcgaacagtt ttattgataa acgtatgcac tggatggaac atgaagatag cttcttcttc
    30001 tcgagggtct tcatcccata atgtcacgta gtctccttca gatttcccat caaaatttcg
    30061 agtgatgcgc cacacttgtt ttttccctgg agtagttact ttttctgcat tgcttgataa
    30121 cttgatcgta tccatcattt ttccttcatc atcttcgatc gatactagct tgaatactgc
    30181 accaagggct ggctgatcat aggctgtgat caattttgtc ccaacacccc atacatcaat
    30241 tttagctttt tgcatcttta aattcaaaat cgttgcttca tccaagtcat tcgaagcata
    30301 gatttttgct tccgtaaatc cggctgcatc taattgttcc cgaacacgct tagatatata
    30361 ggccatatct ccactgtcga tgcgtacgcc ttggaagttg attttgtcac ctaattcttt
    30421 cgccacgcga atcgcacttg gcacacctga tttcaacgta tcataagtgt cgactaagaa
    30481 cacgcagtct ttatgggttt tagcgtaggc cataaatgct tcataatcat ttccataaga
    30541 ttggactaac gaatgagcat gggtcccgct agctggtatc ccaaatatct tcccagcacg
    30601 tacattgctt gttgcatctg ctccgccgat atatgccgct ctagttcccc agactgctgc
    30661 atccagttct tgtgcccgtc tagttccaaa ttccaatagt ggatcttctc cgatgacaga
    30721 tttgatacga gctgcttttg tcgcgatcaa cgtttggaaa ttgaccatat tcaacagtgc
    30781 tgtttctact aattggcagt gcgctaaagg cccttccact tggattaatg gttcatttgc
    30841 aaaaactagt tctccttcac gagcagaacg aactgttgct ttaaattcaa aattttgtaa
    30901 atactccaaa aaaccttcag gatagacttc taatccacgc aagtaagcaa tatcggaatc
    30961 attgaacgtc agattctcta aataattgac taaccgttcc aatcctgcaa aaaccgcgta
    31021 tccgtggtta aaaggcattt ctcgaaagta acattcaaaa acagcatgta aatcagctcg
    31081 acctaattcc cagtatgtct gcatcatatt gatttgatat agatccgtat gcagcgtcaa
    31141 actgtcgtct gggtaagtat tattcatctt gtattactcc tcttggcaag ttttcatttc
    31201 ctacccatta taacaaaaaa aattaatagg aaaagaaatc ttccattttt tctgaaaaag
    31261 cacatgtttt acggatattt cttgctaaaa atgaactcca tctgctaaaa ctatcctttc
    31321 ttattggtat ttaacctaaa cgagaaagaa tacttatttt attcaatgta tccgagacac
    31381 gaagaaatta gcgttttcta tttttcttac ttgataaaat aagtagattt tcctactaca
    31441 atcgtagccg ttaagatacc gatgattgaa caaatataac caaatgtctc tacaacataa
    31501 tcaatggcaa aagtttttga agcaataata cgtctttcct tttttgcttc ttatccccaa
    31561 agaaacggat ataacttatt atgtattgaa tttttttgga aaggcgaatt atgacaagat
    31621 ataccttgcg ttgaaaaaac tcgcggaaaa aatatcacac gtttttaaaa agatacaaag
    31681 taagaaagca gctgtcaata gaatggaaac aaaaatggcg agacatcaat cagtctcgcc
    31741 ttgtttttta ttgtatacat tagatatgga gcaggttacc ataaagatga ttattagtcg
    31801 ttattaaata gaatccttcg tatttttttg ttctatcact acaatatctt tatttggacg
    31861 tttgaattgt attccggcac gttctagctc ctgtttcact cctacatgga ctttgacatc
    31921 ttctcgtgtc atttttaaaa cgtgatgaat cgcatagtcg atttcttgcc ttgtgatttt
    31981 tttcttcgta ttgatcatca cgacttgctt tttatcatat gtgtctacca atagcagttg
    32041 tgttcgatct aacgaaaata atttgtaata attaatagcc gtattcccaa aaaagaattc
    32101 cactacttta ggataaaatg tcttaatatt taaattacta ttcacaggtg tttcgattag
    32161 cttcatctca ttcctctttt ctatatagtc gatttagatc caatcttaag ttatgttacc
    32221 atctttccta gcattaagga atcggttaca attgaacctt taaagacaaa aggatttacc
    32281 ttttatcact taatagtata acataatttc gtgagaaaaa aatacaattt tttcttgacc
    32341 atctcgttac gtaaaggatt atgcttacat ttgtcaggag gaaaaataat ggagtacaca
    32401 ataaagaaaa tgtcagagat atcaggagtc agtccgagaa ccttgcgctt ttatgatgag
    32461 attggactgc taaaaccagc taggatcaat tcttcaggtt atcggattta tggcaaaaaa
    32521 gaagccgatc gtctgcaaca catcttattt tatcgaacaa tggcattcaa gttggatgat
    32581 atccaagagg tcttagacaa tccatctttt gaccaccaga aagctttaat caagcatcag
    32641 caaatgttgc tggaaaaacg ggcacaaatc gataccctct tgacaactgt ccaacagaca
    32701 cttgatatgt acgaaggagg aagaaaaatg agtgacaaag aaaaatttga agggtttaaa
    32761 caacaaaagt tgaaagaaaa tgaagaatcc tatggacaag agattcgaca aaaatacgga
    32821 aaaaaaaagg ttacagcatc caatgaaaaa tggatgaata tggataaaga aacgtatgaa
    32881 gaaatgcaaa ctgttgaaaa gcagatgtta tttgatctca ctctttactt aaaagaacca
    32941 gaagatgaaa gcttagcaga ccgtatcttc caagctcata agaagtggtt ctcttacagc
    33001 tggcctgaat atcagccaaa agcgcataaa ggactaggaa tgatgtacga agccgatgaa
    33061 cggttcactg catattatga cgagcgaagt ggtcatggtg cagcaaaagc tttaaatgaa
    33121 attatccaaa aaaaggcgta atcttttaca tgatccaaca aaaaagtaca cgtaaaatga
    33181 cctaataaca aaacagcaga cacccaagtt agatttttat gctaactttt ggtgtctgct
    33241 ccattctttc acaagttttt tcatcctact ttaaatatat tcatcgttga ataaacgtat
    33301 aaggtatttt cactttatcc tttttttctg taagaaacaa ttgaaatgcc atttctccgc
    33361 aagcttccag atggtggtcg atggttggga aaccaagaag ctcgctgatc agcaaattat
    33421 cgcgtccaat caccactggt gtcttatctt gcagatagct ttgcaagatg cctgctgcaa
    33481 ccatatccga atttgtaaag acaccatcaa ctccaagctc tttaaaaaag aagcctgctt
    33541 gttttccttt ctctgcatct atacaatccc aaaaaacaag tgattcatca aaagatggaa
    33601 aaagttgatg acatagctgc aaagtgattt ttgagttata acttagcctg ccacttcgcc
    33661 ccaacgtgat gcccaattgc tttatacctt gctgcttcaa ataagtaaga ccttctgtaa
    33721 ttgattgttc tcgatcaata aagacacagc ttgcctgttt tcccttgatt tcttcacaaa
    33781 aaactagagg tccatatttt tgatatgcca ataaatcatc tagtgtattg gcacgagacg
    33841 taatgatcaa tccatcgaaa gctttagctg caaattcttc aagatacctt cgctcttttt
    33901 ctttatgata gcccgtcggt aaaagtgtca ctttgtaatc ataatcaaac gctgcttcaa
    33961 tgatcccact gatcaactga tcaaaatacg gatgattggt ataaggcaga atcactccaa
    34021 tgcttttcgt ttttccataa cttaactgtc tggcatttgc attagggata taatcgactt
    34081 ctttcatgac cgcaagtatt tctttccttt tttcctcatc tacatatgga tgtccattga
    34141 ttacacgtga aatagtagaa actgaataac ctgtgagctt tgcgatatct cgaatgtttg
    34201 ccactgctgc ttcgccacct atacaaaaag attttcttgt aaatagtcta ccacagctgg
    34261 accgcattca aaaaactgat acatttttcc ttcatgcgaa aaactgatcc gctgcccgcc
    34321 ccaatatata tcttttgtca aattttcgat ttcattcatt ggtatttctt ttactatatt
    34381 cctattcaac ccttgaaaac tgtacaacgt taatacggat cccttgaact cgacaaacgc
    34441 ataaaaataa ttgttcgttg tgccatctgt tatctctaca taagtattca ttgcaagccc
    34501 tccttttgat actttgagta tagtgtatga aacgcgtctc atagcaagga gtttgttttg
    34561 ccaaagaaaa gttttattcc tctttcatta ttaccaaagt ctcttatttt aaattgaata
    34621 cattataatg atactgtaaa tatatcttta ttattagtga atggagtcaa gtccacaatc
    34681 ttgtgtaaaa gttcaacctc atcaaaagca caatgttttg cgttgtgaac ctaactgcca
    34741 tgcctttctt tctgaggaga gaggtcagga gcagtagcgc agcgactctt gatgtctctc
    34801 ctcagaaaga agagactcgc acaggttcat ggtgctaaat gttattcgaa ttaaattcta
    34861 aatattttcg tggagaagcc agccactcag tgtctttttc catcaaaagt gttccaatta
    34921 tccgagtgat ggaattgata tttggaaaaa tccgaatcac tcgttctctc cggcgaatct
    34981 cttcgttcaa ccgttccaac acattggttg tacgaatcct tcggcggata ttttcaggaa
    35041 aagacaaaat ttgaatagca tcttcaaagc cgttttctaa aatgtcgcaa gcagcactta
    35101 attttgaatc acaaccatat ttttccaaga agtgctcttt tctttcacgt gtcaattcaa
    35161 gttcagaggc tttaaagata ctcttcaact cgtcttttac atcagaagaa actttctttg
    35221 gcagcttatc aaaaatattt ctcaaaaagt gggcttggca tctttgccag ctcgcaccta
    35281 aaaagttctt gcgaacagcc ttaactaacc ctttgtgtgc atcagaaatg accagtttta
    35341 caccgaacaa acctcgttga acgaacgatt gaaaaacggt atcccaatta tcttccgatt
    35401 cgccgtcttg aacatcaaaa ccaagaatcg tacgtcgtcc atcagaatca atgccgatac
    35461 caatatatac accttttgag acaatacgat gattttccct tactttcata tacagggcat
    35521 cacacatgaa aaatggatat tccgagcctt ctaggctccg gtttctccac tcaaaaacaa
    35581 atggatccaa ctgtttcatc agatttgaaa cgaatgattt agaaacagtc gcaccatccg
    35641 ttagcagttc aactgtttta gttactttgc gagtggagac accagaaatg accatttcaa
    35701 tcatggcagc gatcaaagct ttttcgcttc gctgatatct ttcaaagata gtaggactaa
    35761 acttaccgtc tctggttcgt ggaacatgaa gttctaacgt accaattcga gttgtaaacg
    35821 aacgatcgta gtaaccattt ctttgtgatt gccgttcttc tgaacgttca taggcatttg
    35881 cctgaatata ttgatttcgt tgttcttcca tcagctgatt aaacatgata gtcataagtg
    35941 tttttgcggt atcattcgca ccgctttcgt ttataattgc ttgaatttct tcgctttcaa
    36001 aagtaaaatg tacttgagtc attgatatca gtcctattcg agtatgtttt ctgcaaaaaa
    36061 cattgtactc ctaactgaga tcaatggctt ttttgatgct tcacttttac acaattatat
    36121 ggacgtaatc gtgaatggat atttactttt aatagataaa atattataac tattaaaaat
    36181 aactattttc attataatta cacacaaaaa agagcgtggg acaaaagtaa agaacacttt
    36241 tgtctcacgc tctaaacacg tataaacagc ggaagcagaa gcaactcctt cggaaataag
    36301 ctgaaattca caaaaatttg aaaagcaatt tccgtgaatt tcttcttatt tcttggagtt
    36361 aaacgcttct gttccagcct ctttttatct gtctttcact aatgatcagt tgtagataag
    36421 caagttgctt tttcttacat cataccgccc atcattgatg gatccattgc aggagctgct
    36481 ggcgctgctg gttctggttt atctgcaacg actgcttctg tcgttaataa caaggcagaa
    36541 acggaagcgg cattttgcaa ggcagaacgt gttactttag ttgggtctac gatacctgct
    36601 tcaaccatgt ttacccattc tccagtagca gcattgaaac cagtgcctag ttccacgttc
    36661 ttcaatttat caacaatcac tgatccttca taaccagcgt tttcagcgat ttgacgaatt
    36721 ggttcttcta aagcacgaac aacgatcttg atacctgttg ccacgtctcc ttctgcttct
    36781 acagcagaaa ctttgctgat aacgttcact agagctgtac caccacctga gaccattcct
    36841 tcttctactg cggcacgtgt agcattcaat gcatcttcaa tgcgtaattt taattctttc
    36901 aattctgttt cagtagctgc accaacttta acaacagcta caccacctgc taatttagct
    36961 aagcgttctt gtaatttttc gcggtcaaaa tcagaagttg tttcagcaat ttggtttttg
    37021 atcaattgca cacgagcttc gattgcttct ttttctccag aaccttctac gatcgttgta
    37081 ttgtctttat ctacaacaac tttagaagca tttcctaagt tttcgattgt tacatctttc
    37141 aattctaaac ctagatcgtc agtaattact gtaccacctg tcaaaatagc gatatcttca
    37201 agcattgctt tacgacgatc gccgaaacca ggagctttta cagctactac gttgaatgtt
    37261 ccacggattt tgttcaatac aagagttggc aatgcttcac catctacatc gtcagcaata
    37321 atcaacaatg gacgtgattg ttgcaagatt tgttctaaca atggcagaat atcttggatg
    37381 ttagagattt ttttgtctgt gatcaagata tatgggtttt ctagaacagc ttccattttg
    37441 tcgttatctg ttaccatata ttgtgataag taaccacgat caaactgcat accttctaca
    37501 acatctagtt ctgtttcgat cccttttgat tcttcgattg tgatgacacc gtcgtttcca
    37561 actttttcca ttgcatcagc aatcaaatgt ccaactttat cagaacccga agaaacagct
    37621 gctacttgtg caatggcttc ttttgaatca acaacagttg agatattatg caattcttcg
    37681 actgctgctt ttgttgccaa ttcgatcccg cgacgaatgc ctagaggatt agcacctgca
    37741 gttacgtttt ttaaaccttc gcgaacgatt gcttgtgtca gaacagttgc tgtcgttgta
    37801 ccgtctcctg caatatcatt tgtttttgat gctacttctg atacaagttt tgcacccatg
    37861 ttttcaaaat gatcttctaa ttcgatttct tttgcgatcg tcacaccatc atttgtgatc
    37921 aatggagagc cgtaagattt ttctagtacg acatttcggc ctttaggtcc taatgttact
    37981 ttcactgtat ctgctaattt atctaccccg cgtaacatag ctgcgcgtgc gtcttctgca
    38041 aatttcaatt cttttgccat gattgattca cctcattgat tatttttgat tattttttta
    38101 tcttccaaat ttactcaaca atcgccatga tatcttttcc tgcgacgatc agatattctt
    38161 ttccttcgta ttttacttct gtaccggcgt atttttcgaa cataacttgg tcgcctgctt
    38221 ttacagcggc aggaactttt tcaccgtttt ctaacaaacg gccttcaccg actgcaacaa
    38281 ctgtcccagt ttggggtttc tctttagcag cagaagctaa aacgattcct ccgacagttt
    38341 tttcttcttc ttttgcgact tcgataatga cgcgatcacc taatggtttt aacacgataa
    38401 atccctccga taactctttt tttaatctgt tagcactctt aaccttcgag tgctaaccta
    38461 catttttaat aatactcatt ctccctcttt tttgcaagct tttaaatcaa agaaaagaaa
    38521 ttttattctg acagctgctt attgaaatta tgatataatt gaaatcaatc gatataagct
    38581 tgccttgcat gcttgttatc ccttaaaagg aggaattaca tgtctttaaa aaaatatagc
    38641 ttcctcagca ttttttgcta tggtctaatt tttatctcac ccttgatcct agcttcgata
    38701 ggacttgtaa aatctacgtc tgaattgatc acagcaactg cagtcatgta tatactaggc
    38761 gccgttgtcc tagctatttt ttattttaag caacgtgaac ccttagcgat cgaatcagcg
    38821 gtaaaaaaag cttctgctcc aaagattgtt atttatggat tggttggaat ctttgtcgca
    38881 ttgattctgc aaagcatcgc tgtcatgtta gaatctgtat tgtttggcaa agcaacccct
    38941 tccgagaata cacaaaatat catccagatg atcatggaag cacccgcttt tattttggcg
    39001 acaactgttg ctggacccat catggaagag ttcgtattcc gccgcagtat actggggatc
    39061 atcagtcgat attcaaattt ttgggtcgga gcagtgatca gctctttgct gtttgcgttt
    39121 gctcataatg atggtcatct gctaatctac tttttcctag gtttcttctt cagcctagag
    39181 tacaaagcaa ctggtcggat ctggacatcg atgatcacac acgtaggaat gaacacatta
    39241 gttgttcttg ttcaattagc tgtccaaaaa gggctagtat aaacatgact ataaatactc
    39301 ctgtcatcct agattggtga ttttcccaat ctaaagcgac aggagtattt ttgtttttta
    39361 gtcgttcatc ttttctgctg ctccatcatt ttttgtctgt ctttcctttt tgcagtttgc
    39421 agaatctatt tttttcaaaa atgggaaata aatgaaaaaa ctaattgaca acacgatacc
    39481 ttgtaaaatc gctgcaggca ctccgcctac taagaaaccc gagaggatcg gcggtgttgt
    39541 ccaagggact tggactgctg taaataaagg aacgaatcca aaatataaag cggaataggt
    39601 aatcaatcct gaaacgaccg gtgcgaaaat aaaaggaaca gccatcatcg ggttcatcac
    39661 gatcggtgtg gaaaaaataa ttgattcatt gatgttgaaa aaggctggta aaagagcaag
    39721 atttcctaat tctctgtatt tcttcgattt cgcaaaaacc gtcataaaaa atacagcccc
    39781 taacgtcaat ccagcacccg taaccgtcat gaactgatcg agaaattgct gagtaacgat
    39841 atgtccgcca tttgccaccg tcaactcttg tcctgaggct aagatttctg cattcgctaa
    39901 tgaattcgct tgcaagacgg gactaaccaa cccattgacc atcgcagatc catgaagacc
    39961 aaataaccat aaaaacggaa caaaaaaacc taataaaagc acaccaaaca acgtgtctat
    40021 gaacgattga atgggaagct ggacatatgt ccatactcct tgaacaacag tcattctgaa
    40081 caactgttga aaaaccgctg aaccgataag cgtaaaagtg actataacaa tgattggaat
    40141 caatgaagta aaagactgcc aaacattttc aggtatcttc tctctttgct tccacccttt
    40201 cgcaagtctt actaaacgtg catagcccca tccgatgatg agcccagttg taactgctcc
    40261 tagtatccct tcagcacctg tccagacagt atctatctga gtatttagtg gctgaataag
    40321 cagtagataa gcagacaagg ctgttatgcc gactggtaag cgatcgatgt cttcttcttt
    40381 tgcataagcg tatgcaatgg caaaaacgat ccaaaaggct atcacatcaa atgtagcctg
    40441 gtatacttgt gtaaaataca tagaaaatcc tgttttgtct atccactgag cgatgtaatc
    40501 cacaggaaaa tgagcaaata agaaaaacag cgagccaaca ataattattg ggatcgtgta
    40561 agtcattcca ttacgcaaag cagttaaggg tctaagattc acaacagatg ttatcattgg
    40621 taaaaaggca cgatctaacc actctttcat ttcttatctc cttcaacttc tatttttatc
    40681 aatcagtttt cttaatttaa ctatacccaa tgatcacgaa ccatgaaagg aatgcgcact
    40741 gagcttttca aaaatcggat tctttgacga atattcagca actgcttaca atggacagga
    40801 ataaaaaagg aggtttttta tgaaaattgc actcattgga gctactggcc atgcaggttc
    40861 atttatttta gacgaagcat tgtccagaga tttagacgtg acggcaatcg tgcgtcatcc
    40921 agaaaaattg ccatcagatg ttccgtttat acaaaaggat ttatttgagt tgacaactac
    40981 tgatcttgca tcttttgatg ttgtcgttga tgctttcaac gctcccaaag gaaaagaaga
    41041 aatgcatcaa acttctttgt cccatttgat tgagatgctt gaaggaaccg atacacgctt
    41101 aattgtcgtt gggggtgcct cttcgttatt cttagataca gaaaagacga ctcgtatgat
    41161 tgaccaagta cctaaaaatg cacccttcta tccaacagct ttcaatatgt acgaaggatt
    41221 gttaaaattg aaacaatcta aaaatctaca ttggacttat atcagtccag cttctttatt
    41281 tgatccacat ggcaaacgta caggtactta tttgttaagt gatgattatt tacaaagaaa
    41341 cgctgctggc gacagtacga tcagcatggc agattacgcg attgcattag tagatgagat
    41401 actggatgag aaacatgaaa agcagcacat cagtgtagtc agtcgataat acggttattt
    41461 ttttaatatg ctaaaaaaat aaaaatagaa gataaaacca accctgattg attttatctt
    41521 ctgcttttta tatttttatt gattgaactg tttaaatcga aaatagctca gttgcttcat
    41581 ctggatctgt atcatagatt tcaaaatcat gtccaacgcc aaaatctttt tctttcaaaa
    41641 cattttccat tgttaaatga gcaagttctt tcatattgtt ttccttgcta agatggccaa
    41701 gatagattcg tttggtccga ttaccgatca catcagtcat gacaagtgca ccgtcttcgt
    41761 tggaaagatg tcctctatct cctaaaatac gctgttttaa attccacgga taaggtccca
    41821 tgcgtaacat ctcaagatca tgattacttt ccatcaaata accatcggca ttttcaatga
    41881 cacctcgcat ataatcactg caatatccgg tgtccgtcaa catgacgaat gaccgatttt
    41941 ctttatggaa acgataaaat tgcggagccg ctgcgtcatg ggagacgccg aaactctcaa
    42001 tatcgatatc gccgaatgtt ctgactttcc ccatctcaaa tagatgtttt tgttccactg
    42061 gtacatttcc aatcagtggt tccatcgctt cccaagtctg ctgattggca aaaacatcca
    42121 aatgatactt acgagccaag acacccacgc catgtatatg atctcgatgt tcatgcgtca
    42181 caagtattcc atctaattgg tccggtgtcc gatcaatttg agccatcaag gaagtgattt
    42241 ttttaccgct aagtcctgca tcgaccaaaa gccgtttttt ttcactttcg atataaagtg
    42301 aattacccga acttccactt gctaggatac tgattttaaa agctggtttt tcttcagcca
    42361 tttgactcct acttcccttc ttactttgta aacttttttc attatactcg cttttttatt
    42421 gatcttccac ttttggtaca gtattgtttg tcacgatcgt attgctgaaa gcgttgacac
    42481 tctcaatttg gaccacttta tcgcttgttt cgatcgctac atgccaaaca ggaacataca
    42541 catttttttc ccggactttc agaatacagg aataagctag ctgacgccat aaaatttttg
    42601 atcctcttgg tattttgtta ttgatgtaca atgtattgat tgcttcctct tccgtataca
    42661 gttccgtctt ttcgcgcagc tgctcgatat cagataaatg cgtctgcatg tatttcgtga
    42721 tgctataatc attatcgttt ttttctaaag aaagaacgat ttttgctgta tcatcattga
    42781 atgggatgcc ttcatactct tggcttgctt ggatttctag tggttcttct tctaaatgag
    42841 aaaagttttt cgtgtacaca taatcattac cgaataaaat attgtctttg ttagataaaa
    42901 aatcttccaa ggaactacta attttatctg gatcgatcac gttcttttca gcatctgaac
    42961 tggataaaga tttcgtcaaa acatcaccgt ctaaaaacac accacttgcc agcaagccgc
    43021 ttttaccagc cttgcgataa ttcgctaatg aagtgctaag attggtctgc tccgcgctaa
    43081 gataatagcc ttgcttgttc tcagacgaaa tcttccccgt gtaagtgata tcgtcgctag
    43141 ccagacgttg ttggattgat tcagtctgat tagagcgaat gacattgttt tcttggtata
    43201 ccgcgtcatg ataactgctg aataaaaaca cattcaaccc taaaaaagcg acgaaaaata
    43261 tccattcgat ttttttgaaa tccaattaat tcgcctccaa tccaggtaat ttttccagaa
    43321 ggtcgttagc tgaataccag ttatctttat atttcacata ccattcaggt aagagatcaa
    43381 cgacacgatt cgtttctttg acattttgcc atgtatagcc aacgatcact gaaccaatct
    43441 tgttgctatc tgctccctta gcttttaact gctggatgat ttcattcgta cttgcaagtt
    43501 ctacttcttc gtctgaaggt atcggcactt gaatcgtatt caaactggtt tggatattca
    43561 cttgcacaga accattcgtt tcaccgccaa cttccacacc aatctgtcct ctgctgtctg
    43621 tcccaaaaac cgggaagcct tccacgaata tccgataatc gatcgtattg tcactgcggt
    43681 caaaatatct gaggttccct aaagaactgc ctaatttgct aatatagggg aaactttcag
    43741 aaaatacact agcattttct tttttctctg gcagctctcc acgaaaatca actacttgcg
    43801 tttccgaatg gatagacatt gtttcattcc caccgtaaaa aatcaattca ttgctttcat
    43861 cattattttt cacgctatct ggtttctgga aaaaagcatt tctaaaaagt gtatagggtt
    43921 gctgtgacag gatataacta tactttttca gtttgatcga atgtttcgta gcatattgcg
    43981 tgtcgatcgt cgatggttct gttgtcattt ctgtccattt tgtgtctttt gctgttaatt
    44041 ctttattgat atctgtccaa ttcaacgaaa tatttgcttc atatacgaga tggttcgaat
    44101 aattcaaaaa tcggattttt ttatttcctt gatcgaattg tattctagta aaatacatat
    44161 tttcgctttc ttttgccaag ttcgacacat ctaaatctaa atcaaatgct tccttgtatt
    44221 ctcttagcaa aaaaggcgca ttataggcca actcaaaacc agagttcaga tttttcacct
    44281 gttcaaactg tgatttgtct cctgaaacta cttcagaaag ctttccaaat cttgctttat
    44341 cgatgatcaa ttgcaatcgg tacacgagat tttcactgtt ggtttcttgg atcattcccg
    44401 aatggtgcca tgtaacatga agcggaagaa agacttcgga agtttttcga ttgctttgag
    44461 actcgatcat ttgagtgttt gtctcatcta cgttgattga actttttcct gctgggctca
    44521 gccagattgc ataagagaag tatatgctta acgcaaccat caaaatgagt cctatacgaa
    44581 cgactttttc agagattctc attcccacca ttcctcctca taaggttcat atggcagcga
    44641 gatataaaaa gtcgaccctt ttccttcctt gctctctgcc caaatagcgc ctcgatgcgc
    44701 cttaatcact tctctagaaa tagctaatcc aagtcctgtc ccaccttgtg ctcttgcacg
    44761 tgctttatct actcgataga accgctcgaa cactcggttc agatcttttt taggaatccc
    44821 caatccttga tcggtgatac ttaaaaccac gttattatgc gtttctaata agcgacaagt
    44881 aatcgttccc ccatctggtg aatacttgat cgcgttattc atgatattat cgactacttg
    44941 gatgatttta tctgtatcta cttcgaccca aagatctctt tgcgtaaatt cacgacggat
    45001 cttataattt ttttcctgat ttcccaccat catatcaaac cggtcaagaa caaaattcac
    45061 taactcgttg aaattgacat attctaattg aagctgggta ttacctgtat ccatgcgaga
    45121 tagatttaag aggtcattga tcattcgaat cattcggtct gtttcatcta gcgttacctt
    45181 caaaaaattt ggtgctactt cctcgtcttt ccacgcacct tcgctcaatg cttcgatata
    45241 actacgcata cttgtcaacg gtgtacgaag ttcatgggaa acattagaga cgaattcacg
    45301 acgttcccgt tctgtttttt cttgttctgt cacatcatgc aagacagcta ctaatccgct
    45361 gataaaacct gattcgcgac ggatcataga aaagtctact cgcaagatca tctgatcact
    45421 ttccaatgta ctggttgaac ggtcaagtac catttcgttt ggatcttcta ataatttccg
    45481 caacgtatat tcttcttcga tatctaaaag tgtcaaaatc gattgtccga ttgcttcctc
    45541 gtttttgata tctagcaagg aaacagccat atcattgatc gtaatgactt tacccctgcg
    45601 atctgtcgca atgacgccgt ctgtcatatg ggatagcacg ctatccaaac gattgcgttc
    45661 agcttccatt gtatcttgag cttcttcaat acgttcagct aactgattga aggtatcagc
    45721 cagctgtcca agttcatctt gtccatgcac tttgactttc cgactgtagt ctcctctagc
    45781 gattcgaatg gcttgttctc tcatttcacc gatcggctgt gtaatcgaac gagcaactaa
    45841 aacagatacg atcattgaaa taaatgccgc aattagtgag gcagtaaaga aaatgactgc
    45901 tgtgttattg atttccgaat atttttgttc gatattactt ttgacgtaaa gagccccgat
    45961 aacggcatcg ccggtcgggg acaggatcgg ttgaacattg atattcaccc gtttatcgtc
    46021 gttatctaaa gcaacataac gtttagtcgt gaaatcattg atatcaacat aatcattttt
    46081 ctttcccaca gcgctttgtt cattgacatc ggttgttcct cggatgatcc ctttttcgtc
    46141 aacgacccgt atttcgatga tatcgctagt cgcactgttt tcaataaatc ttttgatatt
    46201 cgcatttacc tcttcatcat ctgcattatc ttttcgattc aattccgggc tgattgttgt
    46261 tgctaatgat tccaccgttt gattcatatc tttaataaat gtattgatcg tggaacgttc
    46321 taaaccacgt ataaagtagg caccaataat ttcgatcgag atcaataaaa tcagaataaa
    46381 ggtaatagcg atcttaaaat tgactgatcg aaaaaagcgg acttttcttt tcatccaatt
    46441 actcctgttc tgggttacgc aaatagtaac cgacaccacg acgtgtcact aaataatttg
    46501 gatggcttgg attatcttcg atcttttcac gcaaacgacg tacagttaca tccactgttc
    46561 gtacatctcc aaaataatca taaccccaaa ccgtttgtaa taaatgttct cttgtcatca
    46621 cttgtccaag gtgcttcgcc aagtaaaaga gtagttcgaa ttcacgatgt gttaactcga
    46681 ttgtttctcc tcgtttcgtc accatgtaag cttctggatg gatcgtcaaa tcaccaatcg
    46741 tcaattccgc aggtgctgcc tcttctggtt ccttcgcagc cgtggcaccg cgacgaagat
    46801 ttgctttgac acgtgcaact aattctcggt tggaaaatgg cttggtcacg taatcatcgg
    46861 cgcctaactc taagcctagg actttatcaa tttcagaatc tttggctgtt accataatga
    46921 tcggcatatc ataagttttg cgtacctcac gagcaacttc taagccgtcc attttaggta
    46981 gcatcaaatc aagtaaaatc aaatcaggtt ctacctcagc aactttttcc aaggcttctt
    47041 ccccatcata tgcagtataa acatcatagc cttctttggc taaattgaat ttgacgatat
    47101 ccgaaatcgg cttctcatca tcgacaacta aaactttttt cataaagagc cacctcttat
    47161 atattattgt cataccttct cattataccg tatttctgct tttgtttcat ctttgcctat
    47221 aaaacaaaag agaaaattaa aatgaaagtg caaaatactt tattattttt tgttctaact
    47281 tcaataaaaa aggaaaacac tgattttcac ctcagtgttt cctttttttg atttatcctt
    47341 ctaaaacttg tacaccgaca cccaataatc ccggaccagt gtggactact aatgccggag
    47401 aaatctggcc aaagtagatt tggtttgctt gtgggaactc tcttttaagt ctcgcttcca
    47461 tttcaattgc ttcttctttc gcatccccat gggcaacagc taagttgaag acctttgcat
    47521 taccgatttt ttctttgacg taagcaaccg ttttatccaa acttttttta cgtcccctag
    47581 cttttcctac tgtgtaataa atcccttctt cattacatga gatgattggg ttaagcttta
    47641 aagcggttcc tacaatagaa gcaactaaac cgatccgtcc acctttttga agatattcca
    47701 atgtcgcaac attaaagaaa acttttgttc tttcgactaa ctcattcaga ttactgatca
    47761 gttgatccca ttctactcct tcttccagcc attttgctgc ttggatcgca gaaaaacctg
    47821 caccaatacc aatatttttc gtatctagta catatgcttc caattcttct tgctgttgtg
    47881 caattaaacg aaccacatta tatgtcccgc tcaatccact ggaaattgtt accgcaagta
    47941 ccttttcata accgtctttt ttgatttgct caaagatttc tgtgatcgac tcaccatccg
    48001 gcaaagatgt accagggatt tcctctggca aacgttgata gatctcttca gaggtaatgt
    48061 caattttatc tgtatatacc tgatctttat aaataatttt caatgggatc atatacatct
    48121 cgtatttttt tatcaattct tctggcacat ccgtacctga atctactaaa attgcgattt
    48181 tattgttttt catttgtttt ctcctctttt aaatattcgg tttctagaac aatcgttttt
    48241 tccgcaagaa gtttcattgc aaacgataaa gttgccgctc ttacagcaat atattctaca
    48301 ggggttgcct ggtcgaattt ttgcggatga gatttacctt gtgctaattg gctgaccatc
    48361 cacacagctg cttcttgttc atcgcaaaat agattatagg cttcacgaat tcctactgtt
    48421 tttccttgga acaatatccc ttctttgatt tcaggaatag tcaatacttg tttcaacgta
    48481 gtgattgcaa gtaaaaatgc tacgtgttct ttgttatatc tttttttaac tggtgctggt
    48541 atcaaaccta gtttaacgta attgtttacc atagaagagg taagcaatgg atgcttttct
    48601 ccttgtatca caggtgaaag ataacgatca actaacgttc tgacttggtc catataaagt
    48661 tctaagtcag ggagttcttc ccagtgaggc agacggaatg tttctagttc cttcccccac
    48721 tccattaatt gctgacgcat tttttccatc ataaccgctc cttttttcat ttcataaaca
    48781 tgatatcaga cttatgataa acattcaatc tagttgcttt aactaggtga tttgattagc
    48841 gggattccat gaaaacaaaa aacaagaagg ctaagccttc ttgtctttta tcgttaagaa
    48901 caggagaccc gccggggaga cggcgggaaa ggagtaaaaa atgaaaaaag tgttagggtt
    48961 tgttctcttg caagaacttt gtttgttggt atgcttatat aatagcgagc aaatgtgaat
    49021 aatctatgaa tgatttccta taaggaagta aagatttttc tgattttctt taaatgtagt
    49081 cttgcatttt aaaattctta gtgctactat tattaagtac tttttgtacg ggccgttagc
    49141 tcagttggta gagcagctga ctcttaatca gcgggtcgcg ggttcgagcc cctcacggcc
    49201 cattgggtgc caaacccacg tcatcagtac atctttggct acttcggtag tttcgaaaaa
    49261 gatgtacgtg atgacatttt ttatatttcg ggtatgaaat tcgggtatgt attttagttt
    49321 tttaattttt aataacaata aaaaagcact caaattgagt gcttttttta agttcactat
    49381 cactaaaact atcactagtt tcattttaaa gcaaacatgt ttctatcact gattttttaa
    49441 atctagcgac aaatccttat tttacaggcg ttcgttcaat tctttagcaa ggtcttcaaa
    49501 tcctggtttg cctagaagtg cgaacatgtt tttcttatga gaaccaccct tttcatttgt
    49561 tctaaagata tataaatgtt gatacatcaa tgtttattct tatttttcta tttacataaa
    49621 tttcgtcgtt tttgataaat gggtactagt ttgggtaccg gttgctaccc tatttttatc
    49681 ctttacaaaa caaacattag ttcgtatact ttcgttgagg tgaaaaacat gacaatcgag
    49741 ctagaggaac atctgctttg gtttaaatac gatccatcag aaaaatttgt caaagattta
    49801 tataaagtct gggatactga agtagtcttt ttagcaattg aaactagcct gctagtcaat
    49861 ctccattatt ctaataagaa ctactttaaa attcctgctg tgaaaacgag aatgaagaag
    49921 ggtgtatact ttttgtttga tatcgtgact gacgtgccgg acgcacgtag cgatcatcgg
    49981 cgttatgact atataaagta tactttcgtt gatccagaaa gatacaaaga ttaaataaaa
    50041 aaataacaaa caaactcgct
//
LOCUS       DBBGSZ010000018        48755 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.018, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000018 DBBGSZ010000000
VERSION     DBBGSZ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 48755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.018"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            23..646
                     /locus_tag="ACIZE5_001419"
     CDS             23..646
                     /locus_tag="ACIZE5_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108568.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1096..2145
                     /gene="trpX"
                     /locus_tag="ACIZE5_001420"
     CDS             1096..2145
                     /gene="trpX"
                     /locus_tag="ACIZE5_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC6108569.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2142..3023
                     /locus_tag="ACIZE5_001421"
     CDS             2142..3023
                     /locus_tag="ACIZE5_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6108570.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3026..3796
                     /locus_tag="ACIZE5_001422"
     CDS             3026..3796
                     /locus_tag="ACIZE5_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6108571.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4075..4929
                     /gene="aroE"
                     /locus_tag="ACIZE5_001423"
     CDS             4075..4929
                     /gene="aroE"
                     /locus_tag="ACIZE5_001423"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HGC6108572.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5107..6270
                     /locus_tag="ACIZE5_001424"
     CDS             5107..6270
                     /locus_tag="ACIZE5_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGC6108573.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6387..6797
                     /locus_tag="ACIZE5_001425"
     CDS             6387..6797
                     /locus_tag="ACIZE5_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC6108574.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6971..9199
                     /gene="topB"
                     /locus_tag="ACIZE5_001426"
     CDS             6971..9199
                     /gene="topB"
                     /locus_tag="ACIZE5_001426"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HGC6108575.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9370..9654
                     /locus_tag="ACIZE5_001427"
     CDS             9370..9654
                     /locus_tag="ACIZE5_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108576.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9814..10050
                     /locus_tag="ACIZE5_001428"
     CDS             9814..10050
                     /locus_tag="ACIZE5_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGC6108577.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10047..10445
                     /locus_tag="ACIZE5_001429"
     CDS             10047..10445
                     /locus_tag="ACIZE5_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HGC6108578.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(11112..12056)
                     /locus_tag="ACIZE5_001430"
     CDS             complement(11112..12056)
                     /locus_tag="ACIZE5_001430"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HGC6108579.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(12352..13296)
                     /locus_tag="ACIZE5_001431"
     CDS             complement(12352..13296)
                     /locus_tag="ACIZE5_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGC6108580.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            13517..14731
                     /locus_tag="ACIZE5_001432"
     CDS             13517..14731
                     /locus_tag="ACIZE5_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6108581.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14753..16768
                     /locus_tag="ACIZE5_001433"
     CDS             14753..16768
                     /locus_tag="ACIZE5_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HGC6108582.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16851..18224)
                     /locus_tag="ACIZE5_001434"
     CDS             complement(16851..18224)
                     /locus_tag="ACIZE5_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGC6108583.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(18250..18534)
                     /locus_tag="ACIZE5_001435"
     CDS             complement(18250..18534)
                     /locus_tag="ACIZE5_001435"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC6108584.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(18536..20551)
                     /locus_tag="ACIZE5_001436"
     CDS             complement(18536..20551)
                     /locus_tag="ACIZE5_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGC6108585.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(20730..21035)
                     /locus_tag="ACIZE5_001437"
     CDS             complement(20730..21035)
                     /locus_tag="ACIZE5_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HGC6108586.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(21124..22155)
                     /locus_tag="ACIZE5_001438"
     CDS             complement(21124..22155)
                     /locus_tag="ACIZE5_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC6108587.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            22362..23237
                     /locus_tag="ACIZE5_001439"
     CDS             22362..23237
                     /locus_tag="ACIZE5_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGC6108588.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(23389..24231)
                     /locus_tag="ACIZE5_001440"
     CDS             complement(23389..24231)
                     /locus_tag="ACIZE5_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HGC6108589.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(24323..26200)
                     /locus_tag="ACIZE5_001441"
     CDS             complement(24323..26200)
                     /locus_tag="ACIZE5_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HGC6108590.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(26197..27618)
                     /locus_tag="ACIZE5_001442"
     CDS             complement(26197..27618)
                     /locus_tag="ACIZE5_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HGC6108591.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(27621..31010)
                     /locus_tag="ACIZE5_001443"
     CDS             complement(27621..31010)
                     /locus_tag="ACIZE5_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HGC6108592.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            31267..32658
                     /locus_tag="ACIZE5_001444"
     CDS             31267..32658
                     /locus_tag="ACIZE5_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6108593.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(32731..33378)
                     /locus_tag="ACIZE5_001445"
     CDS             complement(32731..33378)
                     /locus_tag="ACIZE5_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6108594.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(33386..34072)
                     /locus_tag="ACIZE5_001446"
     CDS             complement(33386..34072)
                     /locus_tag="ACIZE5_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6108595.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(34078..35151)
                     /locus_tag="ACIZE5_001447"
     CDS             complement(34078..35151)
                     /locus_tag="ACIZE5_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6108596.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            35373..36047
                     /locus_tag="ACIZE5_001448"
     CDS             35373..36047
                     /locus_tag="ACIZE5_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC6108597.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            36052..37392
                     /locus_tag="ACIZE5_001449"
     CDS             36052..37392
                     /locus_tag="ACIZE5_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGC6108598.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(37541..38527)
                     /locus_tag="ACIZE5_001450"
     CDS             complement(37541..38527)
                     /locus_tag="ACIZE5_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HGC6108599.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            39251..40282
                     /locus_tag="ACIZE5_001451"
     CDS             39251..40282
                     /locus_tag="ACIZE5_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6108600.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            40391..41923
                     /locus_tag="ACIZE5_001452"
     CDS             40391..41923
                     /locus_tag="ACIZE5_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HGC6108601.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            42062..42874
                     /locus_tag="ACIZE5_001453"
     CDS             42062..42874
                     /locus_tag="ACIZE5_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HGC6108602.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            42864..43349
                     /locus_tag="ACIZE5_001454"
     CDS             42864..43349
                     /locus_tag="ACIZE5_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGC6108603.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            43372..43917
                     /locus_tag="ACIZE5_001455"
     CDS             43372..43917
                     /locus_tag="ACIZE5_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HGC6108604.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(43990..45633)
                     /locus_tag="ACIZE5_001456"
     CDS             complement(43990..45633)
                     /locus_tag="ACIZE5_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HGC6108605.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(45762..47990)
                     /locus_tag="ACIZE5_001457"
     CDS             complement(45762..47990)
                     /locus_tag="ACIZE5_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC6108606.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            complement(48023..48502)
                     /locus_tag="ACIZE5_001458"
     CDS             complement(48023..48502)
                     /locus_tag="ACIZE5_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6530 family protein"
                     /protein_id="HGC6108607.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
BASE COUNT        14833 a         8981 c         9174 g        15767 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
      721 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
      781 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
      841 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
      901 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
      961 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
     1021 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
     1081 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
     1141 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
     1201 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
     1261 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
     1321 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
     1381 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
     1441 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
     1501 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
     1561 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
     1621 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
     1681 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
     1741 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
     1801 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
     1861 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
     1921 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
     1981 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
     2041 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt
     2101 acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt
     2161 cacaaggcat gctttgggca atattaggat tagggatttt catgacttat cggatcttag
     2221 actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag
     2281 ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga
     2341 tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag
     2401 ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc
     2461 tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt
     2521 actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat
     2581 tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg
     2641 ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg
     2701 gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata
     2761 aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc
     2821 aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc
     2881 tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg
     2941 ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa
     3001 cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa
     3061 agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat
     3121 cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt
     3181 caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct
     3241 gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc
     3301 caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag
     3361 aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag
     3421 actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt
     3481 atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt
     3541 actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg
     3601 attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat
     3661 ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca
     3721 agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga
     3781 agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca
     3841 ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa catatttggg
     3901 tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg
     3961 acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc
     4021 gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt
     4081 tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca
     4141 ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa
     4201 gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt
     4261 gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag
     4321 gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc
     4381 tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa
     4441 aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagct
     4501 gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa
     4561 gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac
     4621 tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgca
     4681 acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg
     4741 catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa
     4801 gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat ctaccaagga
     4861 gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg
     4921 tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa
     4981 aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa
     5041 tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga
     5101 accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag
     5161 cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag
     5221 gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac
     5281 gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt
     5341 ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa
     5401 atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt
     5461 aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg
     5521 caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa
     5581 gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg
     5641 aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag
     5701 atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaaat
     5761 tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc
     5821 gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt
     5881 gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca gtacgcacgt
     5941 ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac
     6001 gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt
     6061 aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt
     6121 tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg
     6181 aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa
     6241 tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca
     6301 aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga
     6361 tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc
     6421 gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat
     6481 acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca
     6541 cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa
     6601 ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag
     6661 aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg
     6721 atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc
     6781 agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg
     6841 gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt
     6901 tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg
     6961 aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc
     7021 cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt
     7081 tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg
     7141 agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac
     7201 cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt
     7261 gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc
     7321 gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg
     7381 gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa
     7441 gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg
     7501 aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg atggcagttt
     7561 ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat
     7621 caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg
     7681 gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa
     7741 ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac
     7801 gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa
     7861 gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta
     7921 cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca
     7981 tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca
     8041 gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca
     8101 tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt
     8161 acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta
     8221 tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa aaagcatcgg
     8281 aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga
     8341 agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat
     8401 ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa
     8461 aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg
     8521 aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat
     8581 cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt
     8641 agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag
     8701 aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat
     8761 cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat
     8821 tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc
     8881 aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga
     8941 atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag
     9001 agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg
     9061 gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg
     9121 gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa
     9181 tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt ccgaaaagtg
     9241 agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa cgttggggta
     9301 ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca ttcattttta
     9361 aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct aaagtatcct
     9421 gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc accaacgttg
     9481 attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca taaaacgaca
     9541 agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc ggctatgatc
     9601 attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg ttaagaatac
     9661 gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt tcgtaagaaa
     9721 aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa tgtacttact
     9781 atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa gtataaaatt
     9841 agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga attcatgggt
     9901 gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt acgaatgatc
     9961 aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa tcaatatgaa
    10021 gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa attatcaaaa
    10081 tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta aaagatgcaa
    10141 atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa gaactctatc
    10201 ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa catccttttc
    10261 ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa ttgaataatt
    10321 gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt accactagtt
    10381 cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa accgcaataa
    10441 aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa ggaatatgct
    10501 gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga aaatatggat
    10561 taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg aaatagtggt
    10621 ttagaactag tgggctgatt ttttatatat tttagtttac ataatatata ttatacaaag
    10681 tagatttaaa aaatgataaa cctctctcga acggtttttt atcaaaaatc gtcatttttc
    10741 catcaaaatc tgcttatgca aaattataaa aaaattttgc agtttttctt actttttttg
    10801 tcgtttaatt gaatgataaa aaccagtttc tttattcagt taatcaaata tgaacgaatt
    10861 agatatgaat cattgtattt gccgttgcgg aaggattttt taattaacca cagataaaca
    10921 ttgataacga ttcgcttatt gtaatcaaca gattaaattt catatgttca tatgtacgga
    10981 tacattttcg gaccgattaa ttttaaccat tctatttatt tgcttaccta ttagatatca
    11041 ataaaaaact gcttaacagc tatttcagct gttaagcagt tttaggattt ttagttcata
    11101 ttcattgttt cttataatac agtgttcaat acttctctta aagcacttgt tgatttgctg
    11161 aacattgctt tttcttcttc gttgattgat aattcaacaa cttcacgaac accattttcg
    11221 tcaacgattg atggcacacc tgtaaagata tctttttcgt cgtattcacc agttaaataa
    11281 gcagatacag gcaatacagc ttgttcgtta ttcaagatag cttttacgat acgtgcagta
    11341 ctcataccaa taccatagta agttgctttt ttacgatcaa tgatctcata agcagcatta
    11401 cggactttat cagcaatcac atctaattca tcttgggcaa tacgatggtc tttttctaca
    11461 atttcaaaca ctggtttacc accgacagtt gtatgtgacc atgcagcaac ttctgaatca
    11521 ccatgttcac ctaagatata gccgtggacg ctgcgtgggt caacttttaa tttcaatgcg
    11581 atttctttac ggaaacgagt tgtatccaat gttgttccag taccgataac acgtgatgtt
    11641 ggcagaccag attcgttcca agcgatatat gtcaaaatat ctactgggtt tgaagcaaca
    11701 acgataatac cgtcgaatcc tgatcccatg atttctttta cgatttggcg catgattgac
    11761 gcatttgttt taactaaatc taaacgagat tgaccaggtt tttggttgat accagctgtg
    11821 ataacaacga tatcagcatc tttacattct tcatagccac ctgaccatac agccacattt
    11881 tcatcgcccc aagccatacc atctaaaagg tccaatgctt ccccttctgc tttttcttga
    11941 ttcacatcga tcaatactaa ttcattagag attccttggt tgatcattgc ataagcgata
    12001 cttgttccaa caaaacctgt accgacgatt actactttac gacttgtttt tttcatgaat
    12061 aaacagctcc ttttcataac tatttgttac tttcatgaaa agtatagtct tgtttattca
    12121 ttttatcaac atgttaatta taatagttgt tattataatt tttgatggaa acgaattcct
    12181 gaatacgcat aacagataaa tgacaaatgt ttacacctat atcccctgat aatacaacca
    12241 aaagtttaga actgaaaata aatccaaaaa aattcgctgc aacgatataa taagacagca
    12301 atcgcaccta aaacaatttt ccttcatatg ctttagtgaa agattttctt cttaatgttt
    12361 atttctccat tcattgggag tacatgttga atacttcttg aataatttga ataaagaagt
    12421 cgtttgttta tatccgatac gattagcgat ttcttccaac gaaaaactcg tttcttgaat
    12481 cagttccaac gcaaagtcga attttttctt tagaaccagt tcttgaaagg aagcatcaaa
    12541 atacattttc aatttattac taagatagac cggattgtag ccaaaatgag ctgctgtttc
    12601 ttttaacgta caagaagtaa aatgcttatc gatataatct aatactctaa gcatctcatt
    12661 ttctgcgcat ccatctgctg atgaaaagct ttgttgttct aataaatgag tcaattcgat
    12721 cagtaatagt gatgtataga gatttaacga acggatctta tgactgtatg tatcaaaata
    12781 aatcaacagc atattttcaa tcaaatgcgt caaacgactt gtttttccgc cgcgaaaatg
    12841 aatgaattgt gtatgttccc ctttttcttt tgatgcattt atcaaaaaag aagaaagtag
    12901 attatttgtg cttgccaaat gattcaatat ctctgtagat aaggtttctt cttttaataa
    12961 gatgttgatt aaaatatcct cttgccctgt gtattcgatt ctttgagtag cttctttatc
    13021 aatgatcacc acgtcacttt cttccatctc tatcctttct ccattaataa tttgtaaaca
    13081 tgtaccgcta tacatataat tgatttcaac aaaatcatgt gtatgctcgg gaacttccgc
    13141 atatcgacgg tgtttactga tatgaatatt tccctgttga aatagatccc ctcggtggat
    13201 ttttggcggt gtctgaagat ggtaagctaa gtttaaatca ttgatattca ttccttgttc
    13261 acgctgcaga gtttcgattg attcttcgtt acgcaaaaaa aatgtctaat tcagctagtt
    13321 ccaattgact ccctcctttt tgtaagcggt ttctttcgct tattagttca cgctgtactg
    13381 ctattatatg caaagctatt tttggtttca taaagacttt ctatggttgg gacatgaact
    13441 tcctgtgatt ccgctattga gagaataacc acttcatact atatttttga taagcgctta
    13501 caaaaatgaa aggaacatgc ttatgaataa aaagatgatg aaattttctc tgctgtcagt
    13561 ctctcttatt ttgacttctg ctggtgcagt cacgtctgca attcccagta tgtcagctac
    13621 ttatgccacg cgttctttat ctgctgttga attattaacg actgctccct cttttatggt
    13681 cactattttt gttttgatta gtagttttat tgctaggaaa atcggacaaa aacaaactgt
    13741 gatcatcgga ttagtgattg catcgatttg tggtatcctc cccctcttct cacaaagtta
    13801 cagtattgtc ttagcttcaa gagctggact aggtattggc tttggattga tcaattcttt
    13861 ggcagtcagc atgattgctg ccttttatca cggagatgaa cgagcctcta tgattggttt
    13921 tcaaagtgca tttcaaggat ttggtgcagc tttaatgaca tttgttgcag gacagctagt
    13981 acagttcggt tggcaatata cctttttagt ctacgccatc agcttaccta ttcttgtctt
    14041 gtttgttttg tttgttccta cacctgaaac aactgaactt caatcgcatg gcacagcccc
    14101 aacaagacaa gtaatcaaaa cgaatcctaa aatgattagt tatggtattt ttctcttgct
    14161 ggtcatcgtg gtatataatg ctgtatcgat taaattagcc acagtcctga cgacttattc
    14221 tctaggaaac gaaactaatg cagcgaatat cttaacaatc atgcaattgg caagtatggc
    14281 tgccggagtt tgttttggct ggcttcagac aaaagcacat cgctatatgc ttacactttc
    14341 tttactactg atgggaatcg gctttgtatt gattgccact gtgataaacc tgtatgtgat
    14401 tgggtttggt gcgatcctaa caggaatttc tttttcgtta ttcattcctt acttattcaa
    14461 ccaagtaagt atccaagcgc ccaagtacgc ggagagtttc aatacttcaa tcttattggt
    14521 tggcgctaat ttaggtactt tcattgcacc atatggtttg ctctttctct cttttgcttc
    14581 tcttgggagt aaaacacttg ctgttttcgt caatggcagt atcttgctgt tgattagcgc
    14641 gcttattagc cttctagtag tacacaggac gaatagaaag acagtgataa gagtagatga
    14701 agaaataaaa gaacaattga caacaaaata aatttgatgg aggtcgtgta aaatgacaaa
    14761 tgaaaaacat aaagatagat ggctttggta tcctggagac tttgagatcc gccatggact
    14821 gctacaaaat ttccaacggg aagaacgagg ttttgactgg ccagcgtact ggtacatgga
    14881 tgattgccat cggaacgtca agtttaagag atattacttt cttgatcaac cttccatgtt
    14941 taaagtgacg atccaaggag ttgggtatgt agaaattaat ggacaaaaac atccatgtgg
    15001 aaaatggctg acttgtccag ctggtaaagc aaaaattcgt atctttgtag gacatacatc
    15061 agggctacca gcgatgttta tcgagggaga cgaagtaaaa tcagatattg gctggacagc
    15121 aagtaatttt attgaagaat atccagctgg ctggagtccg ctttatgtcg atatcgcaaa
    15181 agatccaaat caaatctatt atcaaaaaga atgcgtccat ccagtcactg aaacggagat
    15241 tggcggagga atcttattcg attttgggcg agcagtgaat ggctgtgtag aactaatatc
    15301 tctggatgac catatcgaat ctatcactct atgttatgga gagtccgatg tagaagctat
    15361 ggatatcgat tattgctact ataagcaaat aggaatgaca agaaaaatga aagctcgtaa
    15421 acgcgctttt cgctatttgt ttataccaga ggtttctact ggaatggttc aacttcaagt
    15481 ttttcatgaa tttttatctc tttcgaaaca agctgctttt tcaagcgatt cttctttact
    15541 gaatcagatc tggtcagtat cagaagaagc cttcaagtta tgtagtgatt tgttttttat
    15601 cgacggtatc aaacgagatc gctggatttg gtctggagat gcgtatcaat cattcatgat
    15661 caatcaatat cttttttttg acgaggaaat caataaacga acgatattag cattaagagg
    15721 acaaaatgaa atcaagcagc atatgaatac tatcgttgac tattcgatct tgtggttgat
    15781 tggtatcgaa aaccactata tgatgacgaa agactatgaa tttttacgca tcgtctaccc
    15841 taagatgcaa tcattaatga gatacttgat ggagcaaacg aatgaattag ggtttattta
    15901 tgggagagca aaagattgga tatttattga ttggtctgaa atggataaag aaggaacgct
    15961 tgctgcagaa caagtcttat tactgaaagc ctatcattcc atgatcactt gcggagatat
    16021 cttagctgaa acatatggag agaacgaaaa ttatcatact catctctatc aagaaaaata
    16081 tcaactattg aaacaaaacc tatttgacta cttttgggat gaagaacttg gcgcttttat
    16141 cgattgctat gaatctggga gaagaaatgt gacgcgtcat gcgaatattt tcgctgtttt
    16201 attcgatttt gctaacaaag accaacagca atcgatctta aagaatgtct tattgaatga
    16261 cactatcaca cagattacta ctccatattt caaattctat gaacaagatg ctttatgcaa
    16321 actcggacag acgaatatcg tctaccaaac gattcttgat tattggggag ggatgttatc
    16381 tcatgatgcg gtaactttct gggaagaata cgaccctact caaacaggaa atgaaaagta
    16441 cagtatgtat ggagatcctt atggaaaaag cttatgccat gcatggggag caagcccaat
    16501 ctatctttta ggacgctatt ttatcggttt gtatccaaca aagccaggtt atgaagaatt
    16561 tatgatacaa cctaatctag attcatttga aacactgaat tgtacgctac ctatcaaaga
    16621 tggaaagatt tcgcttgaaa aaacaaaaga taagatcgtg attacttctg atagaacagg
    16681 cggaacagtg aaaatgaatg gtaaaagtta tcctcttcta gcaaaacagc cacttgtctt
    16741 aacaagctat tcaaaaataa atgcataaaa caaaaaactg cttgcgacat atcagaagac
    16801 tttaaatctt cttctgatat tgtccaagca atttttattt tgaagtttgc ttaattctgt
    16861 tctttagaaa caatgtttgt tctttttccg gcaaaaagaa agctagataa tacgacaagt
    16921 aaaaagaaag cgatgattcc aactgtcaag gctatttgac cgtattctcc tagtttccca
    16981 agtacaagtc ctggtactag ataatcagta tcggcaaatg tagaagaagc gattttaaga
    17041 tctcctaata ctggaaggat aaataatggc agccaactaa tcaataagct attgaaagca
    17101 gaacctaata ccgcccctct tctaccgcca gtcgagttgc cgaagacacc agaagcagct
    17161 ccgcagaaga aatgtcctac taccccagga atgataactg tagtttgcaa gcctatcata
    17221 gcaaacatgg atagtgttcc tacaaagaag ctaacaaaaa agccaattaa tacagcatta
    17281 ggtgcatatg gaaaaacgat aggaacatct aatgctggtt tagaatcggg tacgagtttt
    17341 ttagcaatcc cttggaatgc tggaacgatt tctgccaaca ccattcgaac cccttgaagg
    17401 acgataacaa acccagctgt gaatgttcca gcttggatca gtgcaaagat tacagcgttg
    17461 tctccattgc ttagttctct ttcaacaaat ccaggaccag ctaacaaagc aagtgcgaca
    17521 tatacgatcg acatcaagag catgatcgat acagtagaat ctcgcaaaaa gctgaaactt
    17581 ttaggaatct ttatgtcctc tgtagaacgg tctttgtttc caaaaaactt tccgatccat
    17641 ccactagaag cataaccgat atttccggta tgccctaacg caacttgatt gtttccagtg
    17701 atgttcttca taaacggttg acaaagagca ggcgtaatag ttaatagtgt tccttcgaag
    17761 accccgccta ataagatcat ccacaaattt gcagtaaacc ccgcgcttac taaaatgact
    17821 gctgttagac aagaaacata aagcattgct tgacctgtaa gaaaaatgaa tttatatctt
    17881 gtgaatctag caagtaaaat attcacgatc atccctacta gcatgatcaa agcagtaggt
    17941 gtaccgtatt gttgcaaagc aatcgccact actgcttcat tgctaggaac tactccttga
    18001 gtatgcagag ctgtttggaa catcgaagca aaaggggtta gtgaattact gattaaacca
    18061 gcaccgccga tcagtactag gaatccgaca aatgttttga tagttccttg gatcacttct
    18121 gaaaatttct tcttctgaag aacgagacca agcagtgcaa tcaaagaaac gaggatggag
    18181 ggctgactga cgattgacac aaacaaattc aacaatttat ccattgatag ttcctccctt
    18241 gaatcatttt tattcttttg acaagatctt cgttactttt tcttttactt cttcgctgtc
    18301 aatgatcgat tgcaaaggta cgagcttttc atcaggtata gaagttagcg tatctttcaa
    18361 agaatgctca atgaagaaat aatcagccat atcgctagat acacttccaa catccgtatg
    18421 acttacttca aactcgtcca catctgctcc aagatctgca agtgcttgtt tgatgttcat
    18481 ctctaccata aaacttgttc ctaatccact ttgacatact gcaaaaattt tcatatcatt
    18541 cgtctccttt tcttatgatc gctaatattt cttcttttgt tgatgcgtgt aataaatctt
    18601 gaagattttg tttattagaa agtagctttg ttaaatttgc caaagcccga agatgtgcct
    18661 cattatcgat agcagctaaa cagatgaaca aactaatggg atgggctgga ttatcaagca
    18721 gatccacagg ttgttgaagt ttcagcaaag acatccctac ttcgtttacg ccatcttctg
    18781 gacgagcatg aggtaatgcg atgtgatcgc caatatggat aaacgcacca tactgctcca
    18841 cgcgctcgat catagctttg atataacttt cttctatttt attttctgat aatagcggct
    18901 gtgcggcaaa tgtgattgct tcttgccagt tttttggttg atccgataat tggatcattt
    18961 cttctgttaa taattcagat agcataggac gttgatcctc cttcttttct aaaagtttgt
    19021 tcattttacg atttaatact tgatagagct tttcttcgtc tacgccttct tttaattcga
    19081 tataaggcag tagcgccgac aacaattctt gggcagaagg cattgaaaat cctggtatca
    19141 gccaatctct ttgtacttga ttgatcagct gatttttttc caagtcagtc atgattggat
    19201 gcagaacata gagagacttt ttcttatcag taagtgtgag aggtacagta gaaaaaataa
    19261 tatcgtaaga agtttcgtca acctcgtgta agcggtcagc tgaattagtc tctgtaaaaa
    19321 agatcatcgg gaataattgc tgaagttcac tttttaagat caatgaagag ctaatgccac
    19381 ttggacagac gatcacggct cttatttttc tatttctttc ttctgcgtcc gcttttctga
    19441 tctctccgcc aaatagtata gtgaaaaaac caatctcttc ttcagggatg ctcttcccta
    19501 ttcgtctttc taacggaagt aatgcttttc ttgtcatttc gtagatggaa gcatattgat
    19561 gcttaatttg atcgatcatc acattaggta aataaaaaga ataggaaata cgaaaatagg
    19621 cagggaccaa gtgataaaag acattcatca ataattcacg aaacgaagca aattctacgg
    19681 ccatcaggaa ttccatgcga tggatgactt ctgaagaaca ttccagcaaa aaatcaagtg
    19741 caggctcctg gacatctcct tcaacgatcg atgctaagca aagagagaaa aatataatct
    19801 ccgaattttg atgttcggaa tagccaaggc cagtcaatac ttgtcgacta atgtcagtga
    19861 ctgcaagaga agccaacagt tcagcatctt ttaccagttc catggatgtt tttccaattc
    19921 gaatggttgt caaactcaaa taataagcta attcatccat tcgatttggt gcgaatcgaa
    19981 gatctgatag tgaaatcgtt ttatctagca aatctctaac tttggcgtaa taatcaatgg
    20041 aaagggttgc ggttaaatac gtgagcccaa atcttccagc aagtgactgc atcaaacgag
    20101 cagtgcgatt ttttgcttct cttcttaata ttgcttctga ccctagcagc ctaaaaccag
    20161 ttttcctagt atacgacagc tgacaatctt ccacttctaa ttcatttctt atctttttga
    20221 tatctgacag gactgtccct ttagaaacct gaagaaaatc ttgaaaatga aaaacagaaa
    20281 cagacgttgc agtcgaataa accatcaaat aaagaagatc tcttcgctct tgttcggtat
    20341 acacagcttc aaatcgagta atatccaaaa atttttctgc ccagtcgatt gctcggaatt
    20401 tctttatacg gatacgggta tcatccacat attcggcaaa aggagttaat tgtttgatcg
    20461 cctcgcttgt atttacttcg atgatctctg ctgctttttc tagactgatt tctcttggtg
    20521 ttttcaggag ataactaatt ttgtagttca cagcgctgtt cacctcctac ttatattcta
    20581 gtatggtagc gcttttaaat cgaggggtgt ttggtacaac ttacagttgg atttttttta
    20641 cgactgtacc gaacgatttc tatcgaatgg atacagaaaa aaagcaggtg accaaatgtc
    20701 tcctgctttt atgaattgat ttcgtccgat caatgatgat catgtttatt ttttgaggtc
    20761 agttcttcaa atttttcttt gacatcttca accgcttttt cgatatcttt ttcaaagtga
    20821 ttgggctcat taggctttgt ttcctcttct acagaatttg aaccagataa agctgtttct
    20881 ttattttctg tttcaccaga gtttgtgcca gctaatgatt cttctttgtc ttctgtttca
    20941 ccagaattag ttcctgctaa agccacttct tcttctgttt taggggccat tgaacctctt
    21001 aatcgtttgt gtttttcacc gtcataattt gtcatgttgg ttcctcctag tagttctata
    21061 ctttttcatc gtacaataag acagtttatg cgtcaaaaaa caaacccgat tcttacaaat
    21121 atgtcatatt tttccttctg attcttgaat gcttttgatt ccttcttcca aaattttcat
    21181 ttgtaagatt gtttcttcat ctttgatgac tttttctgcg ccattaacta atgtctcgta
    21241 aatcccttcg tagacacggc tgtaatcacc aacctcggaa attacttttt cttcatgata
    21301 actcccttgt tcatctatat aggtcaatac accataatgt tcgggcaaat cgataccaaa
    21361 gtcttcatga tcaggcatgt aaaacatttt cagatgttct tcttgtcgat cttttgtttg
    21421 tttcacgaac atcccttttt ttccgtaaac gacgaaactt ggacgttctt tgatgcggaa
    21481 ataactggat tttatcgaaa ttttcatatt tccatagaaa aaatccagat cgaagtaatc
    21541 attcattcgt cctttcccta aaagttgacg tacatcatag ctgatatcat ctggttcgcc
    21601 gaaataagaa agaacttgat ctactgtatg acaagcatgt ccatataaat agctgttcgc
    21661 agtagaaaat tcatgcgtat tttctggtac ttccggtctg aaataatcat aatgcatttc
    21721 tacttctaaa atatccccta attttccgct ttcgattact ttttggactg tcaagaagtc
    21781 agaatcgaac cgtctgtttt ggtaacattg gataaataga cctttttctt ttgctaatgc
    21841 aaataactct tctgcttcct ttgacgtttc tgcaaaaggt ttctctacta gtacattctt
    21901 accatgttcg agtgccattt ttccatattc ataatgaaat tgactaggtg tagtgatgac
    21961 aactaattgg atctcaggat catcccaaag atcagacagc tgatcagtat attcgatgtc
    22021 ttcgaatgtt ttccacactg gttcagatgg ggaaaaaatt tttttgatat tgattttgtt
    22081 cgtaagtttt cttgaaaaag gcaaatgata gcgatttgta ctctttccat tgccaagata
    22141 agcgattgta agcatgagtg gtgcctcctt ttattgatgt tttcagtata tcctagaaaa
    22201 gcgcagaaag tatttataat agctattctg gtaaaaaagt tcagaaaaac acttgttatc
    22261 attcggtttg gtgaaattaa tgttcaaagt aaggataaaa atcaaaaaga tagtagcgga
    22321 accaagtgtt tatcagtaag atagaatttg gaggtcagat catgcttatt gaagaaaaac
    22381 taacaaaaca agagttgttt accacgacag agaaacggat tgtcgattac atccgtagga
    22441 atatcgaagc tgcagtctac atgacgattg aagaattagc aaaagctacg tatacttccc
    22501 attcagctat cattcgttta tgcaaaaaaa tgggattcag cggatttaaa gaattccgtt
    22561 tcgagctggg gcgggaagtt catcaattga ttgctcagtt caatcaaacg attgatccta
    22621 attttccttt ttcaagtgaa gatagcactc agcaaattgc aaagaaaatg gcggatttat
    22681 cgatccagtc aataaaaaaa gcacaattgc agattgaaca tgaagattta gatcaaatcg
    22741 gtaaagtatt gaacaaggca cagcgaatct ttctttttgc aaaaggtgat tctcaaatca
    22801 cggcaaggaa attccagaat aaaatggtca agttgaataa gtttttgatc atggctgaag
    22861 aatacagtga ttcttcttgg aatgcagcca atttgactag cgaggattgc gccattttta
    22921 ttagctacag cggtcgcatc catcattatg aacgaataat gacctatttg aagcatgtag
    22981 aggcccctac cttgctgatt accggaaatc agcattcaga aatggccaaa caggctgata
    23041 tgtgtcttgt tatatcgcag gaggaatatg attttgctaa agtagcgact ttctcctctc
    23101 aaattgcctt cgattacgta ttaaatacgt tattctcagt gatatattct caaaattttg
    23161 aagagaatat ccgcaacttg aaaaacaaac aagaattgat gcaaaaaggc cttcttaaag
    23221 aatatcggaa aacttaagaa aagatcctca tttagtaata agaaagatag tgtttgatag
    23281 gctctctttg atatcatcat aaaaacaggc tgaagttttc tttttcaaac ctcagcctgt
    23341 ttgtttacgg aacgattcga atagatatat tatagaaatg aggaatagct aacttctgtt
    23401 tcttattttg aacgattgac gaaaaagata tataagaagg aggaaaatca gtatacatgc
    23461 agctaacaat ccatacagga aaaatcgttt gttctcggat actttctgta cttctttttg
    23521 aacttctttt gcatgataag gaacccggtg ccctctgaca agtaagcgat gactgttgac
    23581 catataaggt gtacaagtta ggagtgtcac gaaatcctgc cctttttcga ttctcagatc
    23641 ttttgtatca gtcggttcta ccgtcttgat ctgatcgact tgataagcga gtgtccgtcc
    23701 attgatttcg atatagaaag aatcacctaa agtcagtttc ggtaagtctg tgaacaactt
    23761 tgcttgaggc agtcctcgat ggctggaaat aacggcatgt gtattttctc cccccgtagg
    23821 ataagacgtt ccttccaata atgaggcacc tttttctagc agcacagtat tcgtttcatc
    23881 aaaaattggc aaatggacat tgatctcagg gatcgtcaaa ataccgatcg tatgtttctc
    23941 aaaataggtt ctatcctttt tcgcaggttc ttttttctta gtaaagggat ctgcacctgg
    24001 atttccacct tcttttgcta attgctggtt tttctttgtc atgttttctt ggattttagc
    24061 catgacttct tcattttctt tgaccgcttg ttgctgataa tgagagatga tctgctgatc
    24121 cagataatta ttcagcgcgt cgctaacaaa tggataagct agtatcccta ttcctgagag
    24181 aagcaagaaa agcatcagca gatctagaag tttccttttc tttggtttca tttgtgttct
    24241 ccttgtgatg actgtttgat aataaaagaa aaaggagcat ttgcgtaatc cgctgctcct
    24301 ttttccaatt cttgcaaaaa gactaaatct gactgtgctt gcgtctagca aagtacagtc
    24361 cagcaatcag tagaaggact actcctgcac cgatatacac atagattccc ttaccgcctg
    24421 ttgaaggaag tgtacctttg tgtttatttg gtattttttc aggagaaatc aactgtcctg
    24481 ctgttacata agattgttca tcgatagtaa atgctacacg gtttgttaat ggaacatatt
    24541 tttctggcgc tttcgtttct tccagatagt acgtgccata ttttagacct gtcacatcga
    24601 ttaaaccgtt acttgtggtt gtaaaaaccg ttgctgattc tttcgccgat acccagctga
    24661 cggcttttgt ggatgggtcg atcgataaat atttcgctgt gtcactatct tgatcacgaa
    24721 cgacgaattc tgctccagca agtgtttggt ctgatgtaac gtcaccatct actttaacaa
    24781 atcgtttgcc cccagtaacg acatcgactg acggtggtgt ttgatcattt gtatgcccgt
    24841 tatcgacatt tgcttggtta gaaaatcctt tggttggatc tgctttttcg ttcaaatgca
    24901 tatagtaaac gaatttcaat gtaccgccag gagttaatga aggaatataa ttcggatcaa
    24961 ctgaaaccgt gaatccgtct gtttgctcag tgacagaata atttactggg tcgatttctt
    25021 tatttccatc atataaggca taagcatacg ttcctgaaga atcattatca aatgttaaag
    25081 cagcgtcatg agtatcgata agtttgaatg ttgtgtactt gttttgcgtt ccttctttat
    25141 cagcgatacc taatgggata ttgacagaaa tctcatattg aattttttca ccgattgcga
    25201 catcttttcc attcaattga ggtgttgttt tatcaacttt agacgtatca tttttgatgg
    25261 tcttttctac tggtgtttgg ctatttgcca ggatctcaaa aggcgtgatt gtttgctttt
    25321 caatcatttc cgcattatca ggagctttta cttcttctaa attatatttt ccaacttcta
    25381 aatgattaac gatcaactgg cctttttcaa tagatgcctc ggcaaagtca ttgttgccga
    25441 tgtcataaga atgaccagta atgaaatgtt tggctttggt ttgatcagtt gtccaagtgt
    25501 acaatccatc tgtgacactt tggatgtatt ttttgacgct tggtgttcct tcttctttag
    25561 aaataataaa ttctgctcca tttagtgctt cgttttcggc agtaccgatt tttgtaactt
    25621 tcaacgttcc atcattaccg actgtatttt tagggtagag atggatagta tctagttctt
    25681 ctgtcccgta tttataagag ccatctgctt gtttgatcat ctcatataca gggaaagcta
    25741 aaaccatgtt tgcggcagct gacactccgt cttttggttc ttctttgatc gtgtagactg
    25801 catctttccc attttgtttt ttaggtaaag ataaagtgac atttccatca gcatctgtcg
    25861 ttcctgaagc aactggtgta ccaggagtca aagactggac tgcttgtttt gctgcatcca
    25921 cggacgctcc tttatctcgt tgcgcataaa attcttgagt gacgttataa actgaaaatg
    25981 aaatatcggc taatccttgg tattgatcga attcgctcat ttctttcccg ctgttttgga
    26041 ttaaaggatc gggtaaatca gtcattttct ttttatgaag gatgacttga gctgctgtct
    26101 cctctgcaaa cacttttttt gcgccgaagc tgtttgtgag taatggtaaa ataaggaaaa
    26161 ggactcctaa cataacgttt atttttttat gatttttcat tttttcactc ctgttctttt
    26221 tttgataaac aaccagattg caaagcttgc gaataccata ccaacaacgc ctaaaagtgt
    26281 atttttcgtt tcgtttgttt ttggaagaaa tggacggcta ttttcttttt tattgactac
    26341 tttcaatata ctgtccgcct ctttatcctc agaaagaaaa gttgaaatgg taaacggaat
    26401 ttctgtttca cttaaaatat aaccagaagg tgcttcgatc tcttttaatc gataacttcc
    26461 tgttttcaac ccggaaattg aaaaagcgcc atttttatcg gaaatcaggt gaagcgcatc
    26521 tgattcgttc tttgtccact tgtatccgtt ggctgtttgc tggaggtaat ttcctgcttt
    26581 gtttttaata aggaatactg cgccagctaa tcgtttatct ggtttatttg tctcgatttt
    26641 gacaaattgc ttactccctg tatatacaga gactttcttt gtactgacac caaaaccaaa
    26701 atccagtgtt ccgttgttgt tgatttcctt gttcgcctgt gctgtactgc ttagctgcat
    26761 ctgataagaa atggtcagtt tttttccagc atatttttcc aacgaaggga tcgaaaataa
    26821 aacatcaaat ccgtgaggtt tcttgtgtat gacaaagcct tctgtcagct tttctccatt
    26881 cgatgaaatc gttaaactat taggtaaaaa cgttaatgct tcatccgcac tatctgacaa
    26941 ttcgaacttt tgatagtcaa ggatatttac aggaattgtc gtatgcaagg aataagtgat
    27001 tttttcacca atcgtaaaat catttctagg ctcttctaat accttctcaa aaggtggatc
    27061 agggtagtcg ttttcttcat ttttaggata caaatggata gttgaaagtt tttgattgtt
    27121 ttgtccatgt acaggaagaa caactaccat attctctgcc ttttctttga cgacttctgg
    27181 tactttggat tcaatgaaaa gatacgcttt atctcttttt tcttgatctt tagcggccag
    27241 agaaaaagaa gcgataccat cttcgttgtt aagagttgta gttgttgctt ctgcggtaaa
    27301 cataccggaa gacgcaccgt tttttgcgat ctctgcttgt gcttcttcta ccgttttgcc
    27361 cttttcccgt agatggtaaa aagaatctgt gacatcataa acttggaatg tgacaccatt
    27421 taatcctcga tacgtttgta ataaagcttt ttcttgtccg tcatttggat gatttttcgg
    27481 cagttgcccg tttgggaaaa gcaatttgtg taaagtaatc tgaaccattt ctgtttctgt
    27541 ttctgttgct acctgagtaa aagctggttt aaatagtaac aagaagagac acatactaag
    27601 ccaaccaagt tttttcatat ttagctgccc cctctttctt ttttcaaaaa aagataccaa
    27661 atagaaaacg cacaaccaat catccctact agatagattc ctaaacggcc aattcctccc
    27721 gtttcaggta atggtacttt tgcctgattc gtgatgtcta aagaaatctg gttgtttttg
    27781 gctcctggtg acagaacaga ttcatgatct tgtccatcca cttgaattga cccatcttcg
    27841 tgtataacta tagtaactgg ctcttttaga ccttggtatc cttctggtgt aaaagtttcg
    27901 gtcagcgtat aagttccagg ttttaaattt tcgaatagaa aggtatctgt ttcttgtcca
    27961 tcttttggcg attctaagtc catttctggt ccctgcagtc tgaattttgc tccttttaat
    28021 gtctgtccgt tgtcttcttt tttgtgtacc gttagatcaa acgcttttag tcgattttga
    28081 tgagtgagcg tccatacatt atttgtcatc tcggtatttt ttcccgtgta aatgattttt
    28141 ccatatttat cgatttggaa ttcataattt cccggcgaag tatcatatcc ggcaggacca
    28201 gctgtttcaa cgactcgata tttaccaggt gtgagtgaat caaaactggc aagacctttt
    28261 tcattcgttg tttggctgtc aattggctga taagtaccat ttgcttcttt tttctgtagg
    28321 gaaaatgctg ctcctttaag atttatctct ttgtccgtcc cttgcatcgc atacttacgt
    28381 actgctacag gaacttcaac aaaaggattt tcaatagtca actggatcgt atcatcggaa
    28441 gtagtgactg tttttccatc aatggttacc gtaccatcag aagcgatctt gatttcccaa
    28501 gtagtctttt tgcttaatcc atgcccttct ggagcttttg tttctgtcag cgtataggtc
    28561 atttcttttt gcaatttgac attttctgga agagaatagg ttccgtcgcc atgatctgtt
    28621 agtaaagtat caatagaatc tcctgttaat ttgaaaacag cgccaataag atccttttca
    28681 cctgtagagg aatttttcgt tattttcaag tttaacggtg tgaattgttt agtatttttc
    28741 catgtcattg catctatttg ttgagaatcg tatcctggta caggtaattc tttgattgtt
    28801 tggtaactga atgcttgacc ttgattattg tattgaggta gtgataatat ctcttgataa
    28861 ctttctccgc tatttgcaga taatttgtca atgtctgcac gttcccacgt atttgttgta
    28921 tctttagctg gtttaatgat tcgaatatat ccgtttttcc aagctgcagc atttgtcgta
    28981 tgttcccgtt gaatctcaaa agtaacttga tctggacgat cagctagatt gttgtcaaat
    29041 tcttcccata actttttgat gtgaagactg actccgggag ctttagcaga tggtataccg
    29101 aattcagcta attcattggt atcaatgttt ggctggaaag ttgtcctgcc gttcatttga
    29161 taccagaaat ttggatggaa gtcctcattt tctgtttgga ttctcacttg gtaatggatt
    29221 tggatttctt ggtcttttcc taaatagatc tgattgctct tgatggtatt tccttctatg
    29281 gaaatagatg gagtgaccgt tgtaggactt gtccccacac tcttgactga aagtgtacca
    29341 ggctgataaa tgaatggttc tgcgattgga tcatttattt gtccattgct tacagttgct
    29401 gagatctgta cagctttttt ggctaggtat tcagagatat ctgttgcatg atcagctgat
    29461 tcatagtaaa gatcgccttt ttcatctgat gaaaccattt gtcgcatacg agactctact
    29521 tctgcttttg agagaccagc tgccggatcg ctttgaagtt ggatgccaag accatgtatt
    29581 tcgattcctc gttctttgag tgccatcgct tctccgatgg ttgcgataaa cgtactgtcg
    29641 attcttctgg atagattgtt ttggtcaggt gcatcataga ttcttgagat tagagaagta
    29701 tttcccggcc gatcttgcgt attagaaaac tgagttccgt aataattgct gcttgattgt
    29761 gcgtgtaccc gctgtacttt ataggaaaat gttggtacac catccgtcag caaaacgatc
    29821 acttttttat gtccatttgg aacggatagc atgcttcctg catctcttag tgctttttgt
    29881 gtaaaagtac caccatttgt ccgtgaaggt gtaatggatt ttacttgatt tttcactgaa
    29941 tcaaatgaac ccatctgtac tgcaccgtta ctgtagctat atccttcgct tgagtagccg
    30001 acatatccca tattgatttt gtctgtgata ccgctatctg ctaaagtatc gacaaaacga
    30061 tcgacaccaa tctttacttc accgatccga ttattgtcgt tcatacttcc tgaccagtct
    30121 acgaccaata cgagatcaag aggcgtgata tctttttgta catttccacg agcattcaaa
    30181 taaacatcaa acaatccggg tgtacttgtt tcctttgcat actttcgtat cgcatagtct
    30241 gcttgattac cggttcctcc atattcgata tacgaatggg tccgatcatt aggatctcca
    30301 ttccaagaat ttataccatc ccattgattt gttccgtttt tattgccttg atgatcaaga
    30361 acatttgtat ttcctgtagg ttgccaactg gctttaggat aagtgccctg atcatctgtt
    30421 gtatattctg taggaatcgt ttgattagat ggcacactca cagctggcaa ggataatgta
    30481 ggcaatgtaa atgggctgac agaattttcg ttttcttttg atgattcttc ttctatttcg
    30541 tctggctttg gtactgacac atctgtatct ttcttatttt ctgtctcatc aataatgtca
    30601 tattctttat tatcgacgat cagcttgttt gcctggctgt ggtaaagtgc tggatcgatt
    30661 ggaaaactca gatcgatagt ttgtttagtg tttgatgaga tttccaacgt aattttcccg
    30721 ctatttacct gataagcata gccatctcct tcttttcttt ccacatcact taagtaattt
    30781 tcgactagac caatttcttt ttctatcttt tcagcactgg tgttattcgc atttagcttg
    30841 atgttcagtg ctttttttcc agactgatcc gaaatgactt cagctgaaat tgtttctaaa
    30901 actgttggat catctgtagt gtctgctatt gcagataatg gcacaaagtt tgataaactc
    30961 aatattatca gcatgaaaat aactttcagt ttcttccctg tggtcgtcat ttttcccctc
    31021 ctttttcttt ttttctgttt tgacgtgaat agtgaaaatt attaaaataa acaggcgtta
    31081 cataatttta tttattttaa tatgataatt attatacgaa gggcgctaaa gggaatcaca
    31141 ccaattttca taccaattgg tttcatttat gaagttgatt ccttcgatta atgagcgttt
    31201 cattgaaaga aaagggttga gggagaaaaa catatgatca ggttgttgga attaaactat
    31261 agaaagatgg aaaaaatcat tcgaattctg tccatttctg acaagtggat gactaaaaaa
    31321 gaacttgcca aacgaattgg tagttcagaa tctacatttg taaggtatat cgaagagatc
    31381 aaaatccgct ggggaacgga tgtaacgatt caatcttcac aaaaattggg gtatcgtctt
    31441 gaacatttga atgtaccagc ttatttaaat gttctgatgg aaatgtcgca aagttctaca
    31501 aacagtcgtt tattaaatga gattattgtc aatccgggta aaacgattga gtattattgt
    31561 gaaaaaattt ccatcagccg gtcttctttt acacgtaagt tgaaacaatg caatcaaatt
    31621 ttagaaagct atttattaaa agtgatcgtt gaccaaggtt ttcagttaac tagccttaaa
    31681 agtgagctcc agttgcgtat ctttgttacc tttttctttt taagttacta cggaagacgc
    31741 acgttgccat ttccaatcga aaaaaagaag atcaaagaaa ttatggtcaa gaataattgt
    31801 cagatgaatt tgtttcagga agaaagccca tatgagcaat ctttctttat tatgtatttt
    31861 gttgtgcatc tcatgagaga atcccaagga actccatttg aatggaaagc tggagactct
    31921 tatgtacagt tgataaatat cgataaaaaa gacttcttaa tcttgaaaaa tctcttagga
    31981 aaattgaagt acagcagcta tataaaagta gtgaactatt ttgtcaatac gattttttca
    32041 gaattttcgg agaaagaaaa aaatgaaatc agtgagcaga tacgaaaaaa tatgtcctac
    32101 tgttcgtttt catccgctga ttgcaaagaa aaaaacgaag aatatgttgt tcaattatta
    32161 acgcaaattt attttttctc ccgtattttc ccatacgata cgactcattt gacgatccgt
    32221 gcaacttact ttgcacagca gatgcaacac cgccagatac gtctatatgc tggatttcgt
    32281 gcagaacttc aattttattc cactctactg aatcagaatc tgatttatta tttatctagc
    32341 tatatctttt ggatgcttat cggtaatcct gaaattcacc attatacttc tgataaaaaa
    32401 atactgatta tcagcgactt aagtcttcga catagtcaat atattgaaga atatatcagt
    32461 gatattcttg ctgtgcataa aattcactct gagacaactg ctattactga agatcagctg
    32521 tcgaaataca atcttctcga gtatgatctg atcgttacga atcaacccat tttgaatgcc
    32581 catgttcctc atatattgat tgatgatagt gtgtcattcg caaatgaaga agaactcatc
    32641 cgcttattcg agttatgaat aatcaaaaaa cagctatgta taaaccaccc tgataaaaat
    32701 ttcaggacaa atacacatag ctgtttcttt ttattgtatt ccttcagcaa tccaacgaga
    32761 tttatagcga aagtctttta acaactcttc ttttgtccaa ttatttgcaa tgagatccgt
    32821 caaagtgttc attacgaggg tcatggaaaa gtataggaaa ctaactgctt cttccgacga
    32881 ttgaatggag aaatgattga ttcttaataa ttccagccat ttttcgttca ttggagaatc
    32941 agccgatagt tctctacgtt tggttgtctg ctgatcattt cgctgggtta acaagtataa
    33001 cctttgccaa tagatacttt cgtgatctaa gtcgcagcac cactctaaat atttttcgat
    33061 ccccaaaaag aaatgttgtt tgttttcgct aatgaatttt aagatatctt gatggactat
    33121 gtgagaactg cttttgatcg tatacaaata agcatcttcc aaatcttgaa aatatttata
    33181 aaaagcaccg cgcgacatcc ccatcttgtc aacgatttct gagactttga cttggctgat
    33241 gtgctgtgag caaaatatct ccagtaatag gtcatcgatt ctctgtttct ttgcgttcga
    33301 taaattgaaa aaagtttctt ttggcatcca catctctcct ttatctctga ttatacgtgg
    33361 atagcccttc attgtcatga aggattcatt ccttcttttt ctcttcttct gtcaagtacc
    33421 catcttccat tcgataaacg cgatcactcc attgaatcat acggacatca tgagtaacca
    33481 taatagtcgc tttttgtttc tcatgagctt ctttaactag taatttgacg acttcatatg
    33541 catgatctgt atccaaacta gctgttggtt cgtctgctaa gatcaagctt ggctcattat
    33601 ataaagcgcg agcaattgcc actctctgtc tttctccacc agaaaggtct ttaggataac
    33661 tatttttaag tgactggata tctaaagatt gcagcaagga atcgattttt gttgaatctt
    33721 ctttttttga agtaacttgg tcaactagtt caaattgttc ctttaccgtt aaaaaaggaa
    33781 tcaaattaga gctttggaga ataaatccta tttctttaaa gcgtaaatct gctcgttttt
    33841 tttctggaag ctcagttagt gagtgaccgt tgatcactat ttctccggaa gtcggtgttt
    33901 gcaatcctcc tgaaatggta aggaaagtac ttttacctga accagaagga ccaatgatgc
    33961 tgacgaattc tccttccttt acataaaaat caattgcttt caaagctgag acctttgtat
    34021 gaccagaacc aaatgttttg gtaacttttt tcatcgttaa tatttttttc atttttatta
    34081 acctcctatt gctgtaattg ggtctacttt ggttatcgta cgtatcgaaa acaatccgcc
    34141 tagcattgcg acaatgatca aaatcccact atatagcaac cattgtgacc aaaaaacagc
    34201 aaaaggcatc gcgcttggta aaatcagact agtcaaataa gcaaacaaaa gagcaagcag
    34261 aacgcctacc accccaacaa taaaggactg tgctactaaa gatttagcga tgaagaaatt
    34321 tttgatccct tgtgctttca ttactccaaa aatagcagtc ttctgaagtg tcatcacgta
    34381 catgaaaata ccgaccacgg cagcaaccac taagaacaaa aagtatatca tcgcatttaa
    34441 ggtcatattt tgggcagaat agccaggaat actttcaatg aatgtcccaa tagttaataa
    34501 ctgtagaccc ttcgatgctt tttctttcga aattttagct gaatccttta ttacgatccc
    34561 attgatcggc tgttcttctt cagaagcaaa cggctgttgt ccatacttca aagcagtcca
    34621 cgtatctagg gacgcataga tgacgggaga aactgtgtaa taagtttcag gaaagatacc
    34681 gacaatcgtc aaaggatcgt cgtaactgcc aattttgatc gtatctccaa ttttatagcc
    34741 tgaatcagcc agattttgag agatgatgat ttcattcttt gttttaaatt catgcccttt
    34801 cgtgagtttt ggtaataaaa atgcttcttt cgttgtgccg aaaactgtaa cattttcttt
    34861 gttttttcct ttgattgctc cgctgtacaa tccgattggt gctttctctc ctccttcaat
    34921 gtatttcaga tctcctcttg ttaattgtga agctgcaaat acttgatttg catcctccga
    34981 caaaacaatc tcttgtgcgt cccaatcatc gattgctttt ttaaactctt ctgaaagtcc
    35041 attcgctagt cctgacaaca tgaatacgac atacgcaatc aagaacataa taccgacgat
    35101 caagccatat cgtaatttag aatagcgaat ttctttgata gctagaaaca tttgtttttc
    35161 ctccctatga tagattgata gtgacaaaat gtcacttgtt gaatagtgta actctaaagt
    35221 gacaatttgt cacttgtgtt gtttttttct tatcaataaa ttgtctaaga catctttcga
    35281 taaaacctta acatgagtca taaaaaattt atttaagcct tatttatgct ttccatgata
    35341 aactaaagtg accaaatcaa tgaggtggga aaatgattaa actattagta gtagaagacg
    35401 ataaagtatt atccaataat ataaaagaaa tactcgctgc aatcggcgag ataacacaag
    35461 tttatgatgg tagtgaagga ctgttcgagt tggaaagtgg agtttatgat cttgcaatct
    35521 tggatttgat gatgccggaa atgaatggat atgaagtgtt agcaaaaata cggaaagaaa
    35581 aaatacagac tccagtattg attttgactg caaaagatag tttggaagat aagattgaag
    35641 gatttgaacg aggtgcagat gattatctaa caaaaccttt ctatcgagaa gaactgatca
    35701 tgcgcgtgaa agcattattg aaacgctcgc taggtctctt tgatgaaaat gttctgaagt
    35761 ataaggatat cagttgtgat ttaaaaagca atgaagtctt gtataaagaa caagttttgc
    35821 ccatacaagg aaaagagttt gaattgctcg tttatttttt acaaaataag ggaatcattt
    35881 tgacaaaaga gcagatattt gaccggatct ggggatttga ttctgatacg acgattacag
    35941 ttattgaagt ttatatgagc aacttacgaa aacatctgcg aagtactgga ttggataaag
    36001 aaatcaaaac cttacgtaat gtcggttata tactgcaaag ggtgtgatgc aatgaatgga
    36061 gatattacac gaaagcaacg tagtcgcttt tttgcgacaa atgtagcagc atttgctttt
    36121 atcttttttc ttttgggatt cattacttta cagatattaa accaatctgc atacagagaa
    36181 acagatctgt cattagagaa aataaatttt gattctcgaa cagtacaatt agagatacaa
    36241 agatatcagc aaggcgatcc ctttttaaac ccgactcaaa cggaacaaaa cagaacaaac
    36301 atggaacagc cattaatgga accatcaaat gaccgtttta acactcaagt gatcttgtgg
    36361 tctaaaaatg gtgagatatt gaataaagca gctattggtg ggcgtttcaa ccaaatcaaa
    36421 gaattaaaaa tggatacgaa aaatctgaat accatccaaa atattgaatt aaatgaagac
    36481 agtggctcat ctgccctctc tttccgttcg attacgaaaa aagcggagac gaatcaagat
    36541 ggcgttgcct acatccaaat tttagaaaat acaaatcaaa tcaagaattc attagcgact
    36601 tttcgcacga ttatgatttt gtgtatgatt gttttttgga ttctctctat tggtatcagt
    36661 tattacttgt ctagtctaag catgcgccct attattcttt cttggagaag acaaaaagaa
    36721 tttgttgaga atgcttctca tgaattgcgc acaccgttaa cgattattca aaatagtttg
    36781 gaacatcttt ttaccaagcc taatcatact attattgaag aatccgaaag catcgctcaa
    36841 gcattgtcag agacgaggcg cctcactgga ttgacttcgg atttgctgac aatcgctcgg
    36901 aatgattctg atcagcagct gctttcaaag caaatgatca atacacaaga atatatcgaa
    36961 caacttgtta aaccatttca agagatggcc atcatagatg gaaaagagtt tattctccat
    37021 aacgatgcaa cattagaagt accaattgat gaaaaaaaaa tccatcaagt tttggttatt
    37081 ttgctggata atgcattaaa atatacgaat ccagaagata agatcatttt ggattcatct
    37141 gttaaccata aagaatggct gattcacgta aagaatactg gcccttctat cagtgaagaa
    37201 gatcaagcaa ggatttttga tcgattttat cgggaagatc aatctcgggc gaaagagact
    37261 ggcggatacg ggcttggctt ggcaattgca aaacaggtaa tcgaacagca tcatggacag
    37321 atttctgtat ccaattatct tccacaagga gtcgatttta aagtccaatt gccgttgaag
    37381 cctaaaaaat aatgcttatc cctaaaaaag ggctgtgaca aaaatcttgt cacagccctt
    37441 ttttgttgcg aataaacggt gttccagaag tagcttcttc ggaaataagc cgaaatttct
    37501 ttaagctgac cacttctgtc acaacctctt tagcttacgc ttacgatttt ttattgcggt
    37561 cttcaatgtg tacatcaccg cttgtgtcaa tatccaattc ttctcggcta acatcttctg
    37621 tcactttttc aacatcttca tgttcttctt tatgaatccc aacttcttca cgaataactg
    37681 tatgtttgct tacatctact tgctcttctt tgattgggat agtaatcgtg tcatcttcca
    37741 atttttcgtc tgttccctgt gaagattgat ctgttactgg tttgcgttcg atgacgattt
    37801 cttcacgttt gaccggtact tctaccgttt cagtatcgtt gaccacatgt ttgtggatgt
    37861 cgacttctcc agttgtcaca tcatgtgtat ttacatctaa tttttcttct tttagttgaa
    37921 ttgtatcatc atctagattt ggtttgcgat cgatgtcttc agtcttgctt gtacccattg
    37981 tatcagtctc gccaggtacg tccatcggat cagttcctgg tgtcatattc aatggatccg
    38041 ttgtattttg aaagcctgtc gtgccaccta cgtccattgg atctgttcca gtgccagttt
    38101 ctaatccagt ccccattgtg cttgctgggc taacagtatc ttgtgtatcc attgtatctt
    38161 ctgttgtttc tggctgacga tagcctttta ctgtgatgac aaattttcca tcagaaatat
    38221 ctcctctata ttgatataaa ggatcatttt ctggtgtagc cgtctcagaa tcataggtat
    38281 caaaagaaaa agtatctttt attttttccc ataaagaacg gtcttcttca ccatccatcc
    38341 gattttcatc tgtttcaaca tctataccag acaatccgtc aaatcctagt ctagatgctg
    38401 cttcatcagt agtataaata acgatatcat ctcgttcata cccttcgtta cgcaaccgtt
    38461 caattactga taatgcttct tccctcgtac tatagcttcc gatgaccgtt aaatttttct
    38521 cttccatgta aattcctcct agcaaataga tttatgattg gtatattgtt acttataaat
    38581 ttattctata ggagacgatt gttttctaca aatatttaga ttggaatttg attaaaacaa
    38641 tttaattgaa atttgaaaac atttatgtta atgaaagtca tattctaata aaatgtcatt
    38701 tgtttctata tgaattttta tgaaaaattt catataattt ccactcgttg tgatggttta
    38761 atttatccaa tccatcaata agcaaacaac ttatataaaa aaggattaat tctcaatata
    38821 attgctccta ccatagaata aatcttcatg taaagtaatg aagtaccaac tatttctaat
    38881 acttctttaa gaattatccc aacaatatcg ttagacaaac cattattgaa taaatggaga
    38941 gccaatcgat tctgaaaaaa tgttttctaa tttttcggaa ataaaagaaa gagcctcctg
    39001 ccattagaac gaaccaaatc catttcattg ctcatgaagt aaccacatag ctaaaaagag
    39061 gataaatcaa ttaaaagatc aaaagaatga ctgcactaat aaaataacta aaaatgtatc
    39121 ttcttacttc atatctttta gctagtactt agttaaaaat ttgcttccta agatcaagac
    39181 aaactgtcta tcttcatttg atgaaatgcg gtaaaatata gaaaatgaac actattggag
    39241 ggaatttgta atggacagca aaactagaaa acaactgcaa gaaaagttaa agcaacgtac
    39301 acacttgctc ccttccgtct ttcaacagtt tttagaagaa aatcgttctt ccctttcatt
    39361 aggcagtcgc tatgaatacg caaaagattt tcatctgttt actgattatt tgagaaaagt
    39421 attttctgaa gaagtggatg atcagctgat tatccattta gaaaaacaag attatcagaa
    39481 tttcttagct aaaatctatc gacatactcg ttcgttccaa actacagcga accaagaaac
    39541 ggagcaattg tttgaaaata gctattacgg gatttcaagg aagcaatatt cattaaatca
    39601 ttttttacga tttttgtatc aaaaaggact gattgaagaa gagatttctc ttttgggtac
    39661 aagtttaccg gaaacaacca aagcagctcc gcgatatatc gatgcagaac ttttcaaaga
    39721 ttttgagcat ttgtttatcc cgattgaagg ctttcaaaca agcagagaag ctagctttga
    39781 agaaaagaat agaccgagga accttgcaat tactgccatt cttctgtatt gcggattaaa
    39841 gatccatgaa gtagtagaac ttaaacgtaa agatgtatct ttgaccaagc agattcttaa
    39901 tctgaataga aaagaaaaca gactgaataa agtaccaata ccaaaagaag cgatgccatt
    39961 tctggagaac tattttaagt taacagcaca aaatacggac gaaaattctt ttgtttttcg
    40021 ttcctcacat gatcagcaaa tttctcctcg gactattcgc caaattttga gcaaaattac
    40081 agtatataaa aacgtatcgc cagaactatg cagaaaaaca tatcgttatt atgcagaact
    40141 atatttagat gatgctgacg cggtaaatta tttatgtggt aatcgatacc tctcatccca
    40201 ttcttttcaa gatatctggg aaaagatggt tgatttttct tatcacgaat tagcggcatt
    40261 cgttcgggtt tcttccatat aaaacaaatg tatgatcttt ttttcacaat aaactatgtt
    40321 attatataaa ggattatgtt acgattatct tgaatttgta tattacttaa caaaagataa
    40381 tggagtgtga atgatggaga ccataacgta ttcccctttg aacttattta cgaattttca
    40441 agaagctgca gctaactttt ccgagacccc gattatcttt gatgagccac tttcagcttt
    40501 cccagaatta ggacttgaaa caacttacaa aaaatgctgc gaaagtgtgt tgaaacgggc
    40561 ttatcaattg gctcatcttg gagtgaaatc cggagacaaa gttattattt ataagagttc
    40621 cgcttttgac acataccttc tagctgtttc tgtgtcttac cttggtgcag tgcctgtcat
    40681 gacttcttat catctaccaa caacaacaat ggaagtattt atcgatcgtt tagaagaccc
    40741 tttcatttta tttgatgatg agacaaaaaa gcgagtgaga gaaatttcaa atggaacaaa
    40801 atcaaaacag attcctattc tttatttaat ggaacaacct gctttgtctg tttctcaatc
    40861 atttttagac aaaaatgaaa tttcttatat gacccatact tctggtacaa ctggtatccc
    40921 taaacttatt tgtcattctg ctcattctat gggatggcgg acgaaatggc aaaaaacagt
    40981 tttcacaaaa atttcggaaa agaaattaat cgcttttcac atctctccag tgcattccag
    41041 attcaatatt ggtatctctt ctttgatgtc catgggattt cctatgatgc ctttagcaaa
    41101 cgcacaaagt tcaaaagttg ttcatatgtt ggaagctcac cggccaattg cactagagac
    41161 ccatccgaat aactttgttc agtggcgttt tactgctaag gagcatccag aagctttttc
    41221 gggtatccga tactatcact ccacttttga tgctataaac aaccagacaa tgaagacatt
    41281 tttgcgaacg tcgatggcac aggatgcggt atttcttcaa gtatatggcc aaagtgaatg
    41341 cggaccaatg attcttaagg ctcatacact agagagtttg aaaacaagtg atgcaagaga
    41401 tatgggcgtt ggactggaag acatgacaag cgctcggatt acagattcag ttgggaatgt
    41461 cctacctgaa aacacagatg gtcatataca attactgtct aaaggacggg ctttgactta
    41521 ttacaaggaa gatgcacggt tccaggaaaa tgtttatggc gattggtggg atagcggaga
    41581 ttacggtttt atggataagc atggccacct atttttgaaa gatcggcaag tggatttgat
    41641 cgaaacgatc aatagtacat tagctattga agacttttta ttagattcgt tagatttttt
    41701 ggcagaagta gtgattgtaa gggataaaaa tcattctcca caaccgatta ttgctttagc
    41761 tcctgataaa gaaatggatt ggaatcgatg gtgggagcaa gtccatgaac ttcctcgctt
    41821 gaacgtccct atcatccgtg attttgatgc aatcccgcga acagctacaa tgaaagtgca
    41881 acggcttcaa atcgagaaag aattaaaatc acaaaagtcc taactattta aggaaagaaa
    41941 gatccatttt ggtctttctt ttctttttgt ttttttaaat tggatgagat aaaaatatgc
    42001 caattggctg tttttctttt ttgaaaattt cgttatactc ttattcatgg aggaaaatgt
    42061 tatgaaaaga atcttgacaa ttggcggttc tgatccattt gctggtggag gaatccaaac
    42121 agatttaaaa acttttgaga attttggtct attcggacta agcgccttga cttctatagg
    42181 ggcactagat attaatgagc gatttatgct ggaatctata tctttggaat tgcttaaacg
    42241 acagttagtt tcgattgata aaatgacttc attagatggt atcaaaattg ggttattgaa
    42301 ttcaagtgaa gcaatcatgg ttgttcgaga cttcataaaa acaaaacaaa atatcccaat
    42361 cattttagac cctgttttgg cattcaaaga aactgaagct gtgatcaatc aattgtatat
    42421 ttcgcagctc atcgaagaac tttttccact tgttacgatg attacgccta atttggcaga
    42481 agctgcttta ctttctggtc aagctcttcc ctcttcgtta acagaaatga tccatctcgc
    42541 taaagaactc actgcttcag gaacaaaaaa cattgtgatc aaaggcggca caaggatggc
    42601 tggagatgaa gctgtggatc ttctctattc aattgatcat tatgaggtat tttctcataa
    42661 aaaaatcgac actacaacag taaacggggc cggttgtgcc ttttcttctg caataacagc
    42721 gaatcttgtg ttaggggcag attttaccaa agcagtagca gaaagtaaaa aatttgttgc
    42781 ccattgtatt tctaatggcg tgctgatgaa cgatcatacc ggaagtgtct ggtctggcgg
    42841 tattcaaaaa ggaggaatga gaaatgaaaa ctaagcaatt aacgatctat gctatgctga
    42901 ttgcgttgac agttgccctt tcattaacaa ttttgatccc tgtaccggct acgaatggat
    42961 ttgtgacatt atgcgaggcc gggatctata ccgctgcttt tctttatggt ccaacgggtg
    43021 gattagttgt tggtgcttcc agtggtctat tgatcgattt gatttcagga tatccgcagt
    43081 gggcagtttt ttcattagtg atccacgggt tacaaggata tgttgctggt tctttcagca
    43141 aatcttctac tcgtatgtgg ggattagggc ttttattagg aagcttagtt atgatcatcg
    43201 gctatggtat cgccggttgg attttatatg attggccggc tggagtggct tctataccag
    43261 gaaacatctt ccaaaatctg attggaatgg gacttgcctt tcctataact gcaagtcttc
    43321 aacgtattca agcacggaag caatattaat tgaaaaagaa ggttttagaa aatgaagttg
    43381 tcagaaaaag aattaaaaga ccaattgact gaaatagtta atgacatatt ggctgaggca
    43441 cacttgaaaa aaggtgatct ttttgtttta ggatgcagca caagcgaagt cgttggagga
    43501 catattggaa aaaattccag tgcggaagtt ggtcaatgga tcatccgtac gttaaaagag
    43561 ttgttggatc ctaaagaaat tgcgctagct gtccaaggtt gtgaacattt gaaccgagca
    43621 ttagtagtag aacgaacagt ggcagaagca aaaaatttcg aaattgtctc tgttgttcct
    43681 gcactacatg ctggaggtgc ttgttctgtt gctgcttttg accagttcaa tgatcctgtc
    43741 gaagtggaac acgtagttgg acaagccggt atcgatatcg gtgacacatc aatcggtatg
    43801 catatcaagc atgtccaagt acctgtcaga cctcgtttga aaacccttgg acaagctcac
    43861 gtgacagccc ttcgctctcg tcctaaatat atcggtggtc ctagagcgaa ttattgaaat
    43921 gagtaattga cagagcaatc tgaaaaactt cctcgcaaag tccaactaat gaactttaac
    43981 gaggaagttt tacttgtttg ttttatataa ccgagcttca taaggtgcta gtatgccttt
    44041 agcttcaaat tctccgctag aggaatttga caagagtaat gtccaggact gatctgcttc
    44101 ttttggaagt tcatagtcag caagtgattc tgttaagttt accataataa gatattgttc
    44161 atcttctaaa tatctttcat agacataaag ttgtggatgt tcatgaagat attctttata
    44221 agaaccgtat atcagacctt tattggtttg tctaatgcgg atcatgttct tatagaattg
    44281 caggaccgac tctggttcat attcttgttg ttctacattg atcgttttgg tatttggatt
    44341 agtgatcagc caaggttcat gtgtagaaaa accagcatat tgttccgaag tccattgcat
    44401 gggtgtcctg ctgttgtctc tcgttgtttc acgaatgata tccaatgctt cttctcttgt
    44461 cttaccttcc gcaagcagcc ttttataaag tcttttcgaa tctactgcat caacttgatc
    44521 gatcgattca aagggcatat tcgtcattcc gatttcctgt ccttgataaa taaatggcgt
    44581 accttgcaaa aagaaataca tcatagcgat tgcttttgca gacatagccc aaaaatcggg
    44641 acgagtatct ccaaacactg aaacggcacg aggaacatca tggttttcca tatataaagc
    44701 gttccatccg ataccatcca atgaagtttg ccaagcgctt aatgcatgtt tcaatttaag
    44761 gacatctaat tgcccttctt tttcttgctg ccagatatgg atatgatcaa attcgaatat
    44821 catatcgaaa taaccgtctt tccctaccca ttgtggtcct tcttctgcag tgacaccact
    44881 tgcttctccg acagtcatga tatcgtactc ttcaaaaaca tgtttcaaat cggtcaaatg
    44941 ttcttcgatt cctgagacat tttgaaaggg tgagaaaggg ttctctgtgg cttttactga
    45001 atattcatct ttttttacat gagaaatcgc atctaaacga aatccatcta tccctttatc
    45061 caaccaccat cggatcatat tgaatagttc ttctttcaat ttctcgcttt cccaatttaa
    45121 gtctggttgt tcttttgcaa aaacatgcag ataatactgt ccagtttcat gagaatactc
    45181 ccaagcagaa ccgccgaaaa tcgatgtcca attattcggt tctttgccat ctaccccgtc
    45241 gacccaaatg taataatcgc gatacgggct ttctttagat tttttcgatt cttcaaacca
    45301 ttgatgctga tccgaactat ggttgatgac aagatccata atcactttga tccctaattc
    45361 atgtgcttct tttagcaata aatcaaaatc ttccatcgtt ccgaatctct cttctatatc
    45421 ttgatagtca cttacgtcat aaccattatc gacaaatgga gattgataga tcggattgat
    45481 ccagataaag ccgataccaa gatctttcaa ataattaagt ttttcacgga tcccattgat
    45541 gtctccttga ccatcgccat tgctatcttt gaaactagca ggatagattt gatagcctac
    45601 tgcttctttc caccattttt gttcttgtat catatcgttt cactccttta acggtccctc
    45661 ttgattataa ccgattctat tttagaagta tccttgttac cggtaactag aaacgaaaag
    45721 ctcaacgaat ctgctaagtg cgttcgttga gctttatttt atcatagata gcgggcaatc
    45781 agttgaatca tttgcttggg aaattcattc aagtcagtaa tatctacaaa acgactttca
    45841 ccgtagatcg acttgatttc ttctttgtct tggccaatag ctgcggagac aaataggatt
    45901 ccttgacgtt catattcttt caaaacagac tggatatctt cttttgcttt tttgcctgta
    45961 taatccggca acgcttttgg ctgaccgtca ctaatattaa gcaacagttt ggttgttgcg
    46021 gattgtctgt ttaatttttc tgctgctaaa cgaagtgcag caccatcacg attgttttgc
    46081 cttggtttca tagtgactaa tttttcattt aaccattgaa atccgtcttc aaattcttta
    46141 taagaaaaca aagaagtctt ttctcttgac gaacggtctg ctgtatctcc gtaaatcaac
    46201 aatgggatat cgactttctt agaaaattcg gcaatggcaa tcgctgcttt ttttgccgct
    46261 tcgatccgat catcccgtat cattgaccca gattcatcga tccgtacagc taccgctaaa
    46321 gaaggttgct catgtggcgg gttctttttg tcaaaatttc tcaaatcacc atatgctact
    46381 ttgcttgcat tgaaccgctg accttcgtat tttccttttt ggtacgtctc tgtttgttca
    46441 ttatccagta actctaaaat ttgccggcta agtgattcta ctattggcat tacttgcatg
    46501 tgtagctcac gtgcttccgg cgtttttcct tggaaagctg gtcggtgaac gatgagacct
    46561 tctttttcat gaatcgtttc cttcatgatt tgtcgcgctt ctttattcag ttgcttcttg
    46621 atttccttat catgtgcttc catgtcagaa gcagacattt cttgagaatc atctcctgtt
    46681 tgttgttctt tttgattttt tccttcgata tcgctactgc gttctttttg catttgagga
    46741 ggaatctcgt ttttttctat tgtttcttct tgtttctctt ctccctcatt tggttcttca
    46801 gcagacaacg atttcttttc atctaagcgc agaatttctt cagcattttc agtgatgttt
    46861 cgttcatttg cttcttcggc gctaatggtt ctttcttttg tatgctcaga ttgaggatga
    46921 ccccattttt cttttctcaa tatgtcctga agttccagta gcaatccact gtcagacaaa
    46981 gcttgttcaa gaattgccaa ttcatctgaa tcagtggata atttatacaa aacttttgga
    47041 taaatcgact ggagtaaatc ttgtccttgc ttataggtat ttgcccaata aaaataagaa
    47101 cgcattcctg ctacaccttt gatggcgtta gcttttgcag tttcatccaa caaacggata
    47161 atctctgcca tctttaagag aagttcttgt ttttggatca tagttttcgc catcgcacgt
    47221 tctgccatga cttctaaggc aggaagatcc attttttccg catgttgcat ccgatctctt
    47281 aaagattcat ttaatgggcg atttccttgg taatttcgat ttgtagtgat cacaatgacg
    47341 caatctggat ggcgacgaat gattcctgtc ggtaaattca acatcccatt tggttcgagc
    47401 gctgagttaa gtgccacaag aacagaggca tctcggatga cagtcggctc ttgaatctct
    47461 aataaatagc ctttttcaat cgctcgaacg atttcagaag ggtaatagct gtaatggatt
    47521 gcatctggat aatcagcttc gatcctttga actagctctg ctaatttttc tttagcagaa
    47581 aaaggatcaa tgccgtaatg gttctggatc agtgtcagta cagcttcaag tgtatctgtt
    47641 tggtaaatag cttctagtaa ttcttggtct tgttccttat tagaatctac tacaggtaat
    47701 aaggctccga aaacatctga tttgtccata tctgcaaaac aggtcacttt tgtataggga
    47761 agttgcagat cagcagatag tgctttggct aattgtgtct tccccgaccc ggcatctcct
    47821 tccaaaagta cgttactgat tttcatttca ggatcttgcc aattcccttt gatttcggag
    47881 gcgatccgcc attcttctgc acttgtccga tggcttttcg gtttcttcca gatcatttgc
    47941 ttttctagcc gtgaaaaggt tcggttttct gttagtgaga aattctccat gcttctcttc
    48001 cccttttgat catctctgtc tattaatatc ctagctcatc taaaagacgt tttaaaatac
    48061 ggaatcgttc cccaatcagt tctccgtctt tttgtagtgt atcgtaatac aaaatgatgt
    48121 cttcatcgat ctttggattt ttggtatcta cttctaccgt cattcggttc ccttgtaatc
    48181 caatgatgtc tacgactgga ttttctggat cataaaattt ttcataacga taagcatctt
    48241 ggaagtataa acttccttgc gcagctaaga tcgctaaatc taaaatacgt gtgattggta
    48301 attcttccga ctgtcgtgac catttttctc cagtatgtcg ccataccttg cctgagatat
    48361 cgacttttcc acgatcattc cactgagcaa ggcccagtga aagccctttt gcatccatat
    48421 ttaatgcatt tcttccatca actttatcat agtcttctac aacgattact ggtttatgtt
    48481 ttaaatttgt tggtatttcc attattttaa ctcctcatcc ttttattttt agtaaataag
    48541 taaattagta gtttactcat ttactaaact atatgcgaca ttatagagga ttgaagtgag
    48601 gattgcaaag aaaaagagct tcattgatag aaataaaaac accatctcgt tcttttacac
    48661 gctcattagt aacatgtaga aagtccaaga tgatgttgga atattttggc tctatacttt
    48721 ttgatgttgg tgaacttcac caacatcttt tttgt
//
LOCUS       DBBGSZ010000019        47469 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.019, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000019 DBBGSZ010000000
VERSION     DBBGSZ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 47469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47469
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.019"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(53..787)
                     /locus_tag="ACIZE5_001459"
     CDS             complement(53..787)
                     /locus_tag="ACIZE5_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGC6108608.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="ACIZE5_001460"
     CDS             1114..1524
                     /locus_tag="ACIZE5_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HGC6108609.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="ACIZE5_001461"
     CDS             1517..2218
                     /locus_tag="ACIZE5_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HGC6108610.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="ACIZE5_001462"
     CDS             2218..3804
                     /locus_tag="ACIZE5_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6108611.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="ACIZE5_001463"
     CDS             3823..4044
                     /locus_tag="ACIZE5_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HGC6108612.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="ACIZE5_001464"
     CDS             4041..4802
                     /locus_tag="ACIZE5_001464"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HGC6108613.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="ACIZE5_001465"
     CDS             5182..5691
                     /locus_tag="ACIZE5_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HGC6108614.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="ACIZE5_001466"
     CDS             complement(5766..6305)
                     /locus_tag="ACIZE5_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HGC6108615.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="ACIZE5_001467"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="ACIZE5_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HGC6108616.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="ACIZE5_001468"
     CDS             7318..8169
                     /locus_tag="ACIZE5_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HGC6108617.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="ACIZE5_001469"
     CDS             8197..8832
                     /locus_tag="ACIZE5_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HGC6108618.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="ACIZE5_001470"
     CDS             8852..9625
                     /locus_tag="ACIZE5_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC6108619.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="ACIZE5_001471"
     CDS             10033..10830
                     /locus_tag="ACIZE5_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HGC6108620.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="ACIZE5_001472"
     CDS             10808..11221
                     /locus_tag="ACIZE5_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HGC6108621.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="ACIZE5_001473"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="ACIZE5_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HGC6108622.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="ACIZE5_001474"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="ACIZE5_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HGC6108623.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /locus_tag="ACIZE5_001475"
     CDS             15998..16558
                     /locus_tag="ACIZE5_001475"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HGC6108624.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="ACIZE5_001476"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="ACIZE5_001476"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HGC6108625.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="ACIZE5_001477"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="ACIZE5_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HGC6108626.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="ACIZE5_001478"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="ACIZE5_001478"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGC6108627.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="ACIZE5_001479"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="ACIZE5_001479"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HGC6108628.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="ACIZE5_001480"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="ACIZE5_001480"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HGC6108629.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="ACIZE5_001481"
     CDS             21905..22483
                     /locus_tag="ACIZE5_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6108630.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="ACIZE5_001482"
     CDS             22535..23017
                     /locus_tag="ACIZE5_001482"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HGC6108631.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="ACIZE5_001483"
     CDS             23134..23508
                     /locus_tag="ACIZE5_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108632.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
     gene            complement(24186..25538)
                     /gene="brnQ"
                     /locus_tag="ACIZE5_001484"
     CDS             complement(24186..25538)
                     /gene="brnQ"
                     /locus_tag="ACIZE5_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGC6108633.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
     gene            25685..26275
                     /locus_tag="ACIZE5_001485"
     CDS             25685..26275
                     /locus_tag="ACIZE5_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HGC6108634.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            complement(26403..27753)
                     /locus_tag="ACIZE5_001486"
                     /pseudo
     CDS             complement(26403..27753)
                     /locus_tag="ACIZE5_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            complement(27921..28661)
                     /locus_tag="ACIZE5_001487"
     CDS             complement(27921..28661)
                     /locus_tag="ACIZE5_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGC6108635.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            complement(28674..30266)
                     /locus_tag="ACIZE5_001488"
     CDS             complement(28674..30266)
                     /locus_tag="ACIZE5_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGC6108636.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     regulatory      complement(30404..30578)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            complement(30834..31130)
                     /locus_tag="ACIZE5_001489"
     CDS             complement(30834..31130)
                     /locus_tag="ACIZE5_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108637.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            31306..32031
                     /locus_tag="ACIZE5_001490"
     CDS             31306..32031
                     /locus_tag="ACIZE5_001490"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HGC6108638.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEMAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            32024..32866
                     /locus_tag="ACIZE5_001491"
     CDS             32024..32866
                     /locus_tag="ACIZE5_001491"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HGC6108639.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELIALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            32869..33390
                     /locus_tag="ACIZE5_001492"
     CDS             32869..33390
                     /locus_tag="ACIZE5_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HGC6108640.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(33643..34206)
                     /gene="def"
                     /locus_tag="ACIZE5_001493"
     CDS             complement(33643..34206)
                     /gene="def"
                     /locus_tag="ACIZE5_001493"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGC6108641.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            34457..34726
                     /gene="rpsO"
                     /locus_tag="ACIZE5_001494"
     CDS             34457..34726
                     /gene="rpsO"
                     /locus_tag="ACIZE5_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HGC6108642.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            34914..37040
                     /gene="pnp"
                     /locus_tag="ACIZE5_001495"
     CDS             34914..37040
                     /gene="pnp"
                     /locus_tag="ACIZE5_001495"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HGC6108643.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            37550..37816
                     /locus_tag="ACIZE5_001496"
     CDS             37550..37816
                     /locus_tag="ACIZE5_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGC6108644.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            37960..39951
                     /locus_tag="ACIZE5_001497"
     CDS             37960..39951
                     /locus_tag="ACIZE5_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HGC6108645.1"
                     /translation="MATTHNTKKISMTGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            40305..41606
                     /locus_tag="ACIZE5_001498"
     CDS             40305..41606
                     /locus_tag="ACIZE5_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HGC6108646.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(41736..43106)
                     /locus_tag="ACIZE5_001499"
     CDS             complement(41736..43106)
                     /locus_tag="ACIZE5_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGC6108647.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(43288..43611)
                     /locus_tag="ACIZE5_001500"
     CDS             complement(43288..43611)
                     /locus_tag="ACIZE5_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HGC6108648.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            complement(43936..44544)
                     /locus_tag="ACIZE5_001501"
     CDS             complement(43936..44544)
                     /locus_tag="ACIZE5_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HGC6108649.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            44874..45590
                     /locus_tag="ACIZE5_001502"
     CDS             44874..45590
                     /locus_tag="ACIZE5_001502"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HGC6108650.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            45603..46298
                     /locus_tag="ACIZE5_001503"
     CDS             45603..46298
                     /locus_tag="ACIZE5_001503"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HGC6108651.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            46382..47011
                     /gene="udk"
                     /locus_tag="ACIZE5_001504"
     CDS             46382..47011
                     /gene="udk"
                     /locus_tag="ACIZE5_001504"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGC6108652.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
BASE COUNT        15391 a         8789 c         9878 g        13411 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaga
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcaccgggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaacaa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcacagcatg acagcattgg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ctagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagttttt ttgcgaaaac tatttttata tcatatatat gtctaaaatc tatattataa
    23881 aagaaatgtt gtttgatcag cttctcttcg gtattagttc aaaacaaaac ggcaaagtat
    23941 atggagctac tttgccgttt tgtttctcta atactcaggt cagtttatag acgctcaata
    24001 aacggtgttc aaaagccagt ttctcggtat taagtcaaat ttatgcaaaa atgtgagaag
    24061 ccattttcaa aaaatatttc ttaatactcg aaactgagcg gctttttcac gacctctcaa
    24121 taaacagtgt tcaagagaca gcctatcggc aataaggctg aacgtctctt tcacaacctc
    24181 ttttatcaat ctgctacttc ttctttctta gcgaaactcc aaatcagtcc gataacaaaa
    24241 ccgataactg ctggtacgat ccaccccatc cccaatttga aaaacggcaa gtagctttcc
    24301 gcaacatata aaagattttg aacaataggt gtttgtttga tagtttctgg gcaagcgttc
    24361 aacccatcaa aaatcgaagc aatcaatgta aaataagtag tcattcgata aacagccgta
    24421 cgctgcttaa acaaaggacc aactaacact agtaaaatca gtgtcattgc taatggatag
    24481 atgaacatca aaacaggcaa cgaaaattga atgatattcg tcaagcctac gtttgccgct
    24541 aaacaaggaa ggatactagc aagtgcaaca aagaatgcgt aatttctttg cggaaacaaa
    24601 tctgtgaatg tttctgcaaa agctgtaatc aaaccaatac cggtcttcaa gcaagctaat
    24661 ataacgataa atgctaataa gatactgcca taagtaccta aataatgatc agcaatctga
    24721 gccagcgtga tcccgccatt ttcacttaga gcaaagctac ctaagctcat agcacctaaa
    24781 taagcgagca aagtataaat gattcccatc aatataatgc tgatcgcacc agatttgatc
    24841 gtgtctttag cgatttcagc aggttttgtt acacccatgt tttggattgt tgtgacaatg
    24901 atgatcccaa atgctaaagc agcaagcgca tctaatgtgt tatatccttg agtaaaccct
    24961 gtgaaaaaag catgctcttg ataatttggc tgaataggcg cttgatttac agaacctagt
    25021 ggattcaaaa aagcaaggag aagcaaagca cctaataaaa ccaaaaatgc aggattcagg
    25081 aactttccaa cataatctaa tatctttgtc ggttttcttg aaaaccacca agccagcaca
    25141 aaaaatacaa tactgaaaat tgctagatat agcgtctgtc tgctaggatc gataaatggt
    25201 gctaaaccaa tctcgaaaga tgtggttgca aggcgaggta aagcaaaaaa cggtccgata
    25261 actaagtaaa gcaagatggt aaaaaccatc gcatatgttt gatttatccg ttttgctaat
    25321 tcatatacac ctgagctttt cgatacacca atggcaatca cccctaagaa gggaagaccg
    25381 ataccggtaa ccaagaaacc tagattcgcc caaaaggtag cagcgcctgc ttcttgaccc
    25441 aaatgaacgg gaaagataag atttccagca ccaaaaaata gaccgaaaag catggagcct
    25501 ataaaaagat agtctttaaa tgataatttt tttgtcatac ataactcctt tacggttttt
    25561 ttaaaagtaa caaaatttcg aaaaatatgc aacaattttc agaaaatttc ctatataaaa
    25621 cgacggttat ttaataacgt aagtgataaa ataaaagcgc tgaatcatct gaggaggaat
    25681 catcgtgaca aagtcgagat tagaagcatt tactgatgga gtggtagcca ttgttttgag
    25741 agttcttgta ttagagatca agatccctaa tacatctagc tttcattctt tatgggtcat
    25801 ccgaaataca ttattagctt ataccatcag ctttatattt gttgcggtga tctgggtgaa
    25861 ccatcatcgt atatttcaga tggcagaacg aattaattac cgagtggtct ggtcgaatat
    25921 ctttttgctc ttttggctga ctttatgtcc ttctgttact agttgggtcg ggcgtaaccc
    25981 tgaagctttt tggcctgaga tggcttatgt cttagtatac acgatgtgga gtttttcttt
    26041 tggtatcttg atgaggcaaa tcatgaaagc aaataaacca gattcccatg tcgtgagagt
    26101 tttgtcaaag gaccgtcgaa gtcttatctc catgatgatt aacttatgct tgattgccgg
    26161 tgtctttttt gtaccgttga tcgggttatt cggacgtttt tttgtatctg gtatttggat
    26221 tttttcctat aaaaaagcag atgcctatta tcagcggttg tttccgggga aatagaaaag
    26281 aggctgggac agaagctttt aactccaaga aataagccga aatttcacaa aaatttaaga
    26341 agcaattttc gtaaattcct tcttatttct cgaagctgac cacttctgtc acaactactt
    26401 tcttacttct tacgttcata tttcatatga tagattagta atagaagcaa gaaccacaca
    26461 ggtgttagta ataaagcgat tctcgtatct tttcctagga acaagacgac acacacaaag
    26521 gccatgtaaa gaaataccag ataattacta aatgggtaca acggcatttt aaatgaatga
    26581 gcttttttgc cgaggatact tttacgatat ttcatgtgcg tgtagacaag catactccag
    26641 ataaacaaga aacaagtagt ggcaatactg cttactagtg tgaatacttc actaggcatc
    26701 acgtaattca agataacaga aatgaaaatg acgatagtag aaaatgtcaa agcattccct
    26761 ggcacatgat gtgttgttaa ctttttgaat tttttagggg cactgccttc ttgcgctaaa
    26821 gaacgaagca tacgtcctgt actataatat tgcactgttg caggcagaag ctgctgcact
    26881 taatacgact aaattgatca aggaagcagc aatcgtgatc ccaatttccg aaaatacttc
    26941 tacaaatgga ctgttatctg gattcaagct gttccatgga tagattgcca taatgacaaa
    27001 aagagatcct aagtaaaata agatgatcct gataggaata ttattgatag cttccggcaa
    27061 cactttttca ggattttctg tttctccagc gactaatcca actaattcta tcccagcaaa
    27121 agcaaaggtt accatttgga aagctaagat aaatcctttt gcaccagttg gaaagaatcc
    27181 gccatgagac catagattcg tgatactggc tgtgccaata tctgtcgtat agtgggtgag
    27241 gatcatataa gctcctacga ggataaaggc aatgatcgct acaactttga tcaatgcaaa
    27301 ccaaaactct aactcaccaa acaatgagac agccaccata ttcaagcaaa gaagaagacc
    27361 taatgcaatc agttcaggaa gccactgagg aacaccaggc gcccagtagc gtacatacat
    27421 tccgatggct gttaaatcgg ccattgcaat cgatacccag cagaaccaat acgtccagcc
    27481 agtgatgaaa gccgcttttt tgccaagata ttctgcaaca aaatccagaa aagaatggtt
    27541 attggtgttt gataacagaa gttcgcctaa cgcacgcata atgaaaaaac agatgcatcc
    27601 agtaataaga taggcgagca atatcgaagg gccagctagc tggatagact ttccggaacc
    27661 taaaaacaac cccgttccaa tcgctccgcc aatagaaatc agttggacat gtctattttt
    27721 cagtccacgc tgcagttctt gctcttcatt catttttaaa tcatcctaac taaaaaagtt
    27781 taattacttc catattaaaa gagttttctg aaaaacacaa ctaagattcc aaaattttca
    27841 gaaatttacc ttttatgagt aattcataaa aaagaactgc ggtaaacacc gcagctcttt
    27901 gtcccaatca gctattgatc ctaagcattt aaaatacgtg aaaggaattc ttttgtacgt
    27961 tcttctttcg gatggacaaa gatatcttct ggtgtacctt cttctgcaat cacaccttta
    28021 tccataaaaa tgacacggtc agatacatct tttgcaaatt ccatctcatg cgtcacgata
    28081 agcattgtca agccagtatg tgctaagtct ttgatcgtat taagcacttc gccaaccatt
    28141 tcagggtcta acgccgaagt aggttcgtcg aatagcaata catctggatt cattgataat
    28201 gcccgagcaa ttgcgacacg ctgtttctgt ccaccagata attgtgctgg tttggcttcg
    28261 atataacgat ccataccaac tttttccaga ttttcgattg ctactttttt ggcagtttct
    28321 ttatctcgtt tcaggacagt tgtttgacca gacatacagt tttccaagac attcatattg
    28381 ttgaacaggt tgaaggattg gaaaaccata cctagattcg ttcgatattt aggtaaatta
    28441 tatttaggag ctaatacatt ttctccatta taaatgatct cgccgcctgt tggtttttcc
    28501 agtaaattga tacagcgcaa gaaagtagat ttaccagaac cggaagaacc gatgatcgtc
    28561 acaacttcac ctttattgac tgttacgctg atatctttca atacttcatt ttcaccgaag
    28621 ctttttctta gatgtttgat ttcaataatt ttttcattca tgattcttcc tccttattcc
    28681 tgcaaatttg aattgtcgat ttcttcaagc ttggtataag ctgaaggacc atcgattttc
    28741 ttttctaccg cccgcaggat tctggtgatc gtaaaggtca tgactaagta gatgatcccg
    28801 acgatcgtaa atgtttggaa gaattggaaa ttcgcaccgg aagcagagtt tccttggaag
    28861 aacaaatcag ctacgccgat tacacttaaa actgctgtat ctttgatatt gataacaaac
    28921 tcatttcctg ttgctggcaa gatattccgt aaaacttgtg gaataacaac ttttctcatc
    28981 gtttggccat gggtcatacc aatggcttgc gcagcttcga actgcccttc atctactgca
    29041 aaaatccccc cacgaacgat ctctgtcatg taagctccag tattgagaga gacaataaac
    29101 aaagcggcaa tcgttcggtt caatgaaatg ccaaaagcga gtgccagacc gtagaagatg
    29161 accattgctt gtaccatcat cggtgttccg cggaatactt cgacatagat agaaagaagt
    29221 gcatttccga ttttttggaa gaagcgagtc agtgcatttc ctgattcagg taccgaacgg
    29281 aagacaccaa tcagtaatcc aagtgtagta ccgacaactg tcccgatcaa tgcgatgaac
    29341 aaggtaagtc cagcacctcg taagaacata ttgccgtatt gtttccaaat cgtagtgaaa
    29401 tcagaaatga tgccaggttt ttcttcacta tcagttgcag caggctgatc tttgactgct
    29461 tggtccataa ttttggttcg ttcatcgtta gagatgccag aaagaatctg gtttactttt
    29521 tggatatccg ggtcgccttt acgcatacca acagaaatct gaacatcttc cgggtttgtc
    29581 tggaagccat ctgcaccgct gaattcaagc atttccaagt ctttgttcac actagttgcc
    29641 gttacacctt ccggacgttc gctgacataa ccatcgatca ttccagaagc taaagctgtt
    29701 ctcattgctg agaaattatc cattgcttgt tgtttctgca catctggtat ctgatcgatc
    29761 acagtatagt ggaatgtatt taactgagca gtaatctttg ctccagaaag atctgctaaa
    29821 ctttttgctt ttgcatattt gctatctttt tgaactacta ctactaattg tgattcgtaa
    29881 taaggatcgg taaaatcaat ttcttttcgt cgttcagcag tagggctcat tccggcgatg
    29941 atcgcgtcga tcttgcctga ttgaagggca ggagccagac catcccattt cgtttggacg
    30001 atgactaatt ttttccctaa accatctgct acttttttag cgatttgaac atcataaccg
    30061 ccggcgtaac tattttggcc ttgaattggc aaggcattat tctcatctgt ttgttgagac
    30121 cagttgaagg gtgcataccc agcctccata cctacgcgaa actcatcgct cggtgttttt
    30181 tcatctgcat ttgccagaga tcccacactg aatagtgaga agacaaaagc aaatagtacg
    30241 gcaactgaaa ccatattttt tttcattttt ttctcccttt ctgattatat gatacacgag
    30301 cggtctagat gaaatgcggt aaagctttat ctgaaaaaat aaaaagcgac cgatttatag
    30361 atataaaaag gccgctaaaa ttccataagg tgataaacct ctcacaaaac atagcgcaac
    30421 ttagcatcac tgctaagaca gtccgcaagc tcttaacttg cgtcccaaca tacactccaa
    30481 gcaaaaaagt gcacatttcg gcgatcctcc ctattcctgc ttctccatgt ttgcttcact
    30541 ccacagggtt aatgattctc gcgacctcta cctcattgat tgaggcatct cgtattcagt
    30601 tatttataca aaaaaagttt acgatactcg agaggctttg tcaatctata actgctgttt
    30661 tttgaaaaaa tactgataaa tatagaaatc tttactttta ccgaaaaaac aatcaaaatg
    30721 tgaatcatct atccattgca aacgatagta taattataca caaaaatgta tgtaatacaa
    30781 taaaaaaaga actagaacag aaaatttcct gtgtccagtt ccatctcgat catttaagct
    30841 gccgctttct ttggctcacg tcctaggatc gcttgcaaaa gaacaacgac gccataaatg
    30901 gctaatatta gataaatcaa acttgagtat tgggtgattc cccagcccca tgttcgatat
    30961 acggctaatg taatggctaa aacaattgcg gcaatcacgt tgaataaagc aaaagcccaa
    31021 agatttccat tttctttgcg tacaagataa aaaacagaga aataaacgct taacgctaac
    31081 caggcgatac aagccagaat aacgccccaa taaataaaga atggtaacat atcgattcac
    31141 ctcactttta tacagcagta ttgtaacacg ttttcattct tttgtcagtg aacattgtga
    31201 taaattgttc aaatgcccat aacacttttt tattcccatt tttctgactt ttcaacaata
    31261 aatttgttcg agtatgggct ataatggaaa gtgaggtgac aaaacatgaa acaattaaca
    31321 gtagacgaag cagcaaaaga gatattagct tatcagcaaa ttacattttt gaccggtgca
    31381 ggggtatcca caccttctgg agtgccagac tatcgatctt tgtcaggaat ctaccacggg
    31441 atggagcagc cggaatactt gctgagtcat caagcaatgg tgaatgaacc ggataaattc
    31501 tatcaatttg tcaaaaagat ttatcatcct gaagcaaaac ccaatatcat tcatttggaa
    31561 atggcacatc tagcgaaaga aaaaaatgtt tgggttgttt cccaaaacat cgacggtttg
    31621 cacgcaaagg ctaaaagccc gcaactcgtc aattttcatg gaagtttgta tcaatgtcat
    31681 tgtcgaaaat gtcaacaaac ggtagactgg aaagaatatc ttcacagcga caaacatcaa
    31741 gcatgcggag gacaaatacg cccagacatc gtgttatatg gtgaagggtt tcaagatgga
    31801 gtcatggagc aggcggctta tgccgtcagc caagcagagc tgatcgtcat tgttggaacg
    31861 agttttcaag ttcatccgtt ttgtgatctg gtacagtttc gccagccgtc agccaaaatc
    31921 ttagtaatca atcaaacgcc tgtttattta gcggagcctt atacgtttat tcaagaagac
    31981 ggagcggttg ttttcaaaaa aatacaagaa ttaggagcag attatgactg aattcaaaac
    32041 cgaaaaagaa aaaatgattg caggcgagct ttattttgcc aatgatcctg agctggttgc
    32101 cgaccgtatg tttgcaagaa gtcaaagcca aatcatcaac caagcagaat cagcggaact
    32161 gcgatcccaa ttgttgaaag agacttttgg ccgtacaggg aaaaaaatct atatggagcc
    32221 agttatcaat tttgattacg gatataatat atttgttggg gagaattttt atgcaaattt
    32281 caattgtaca tttttagatg tcagcacgat tgaaatcggt gataactgca tgttcgctcc
    32341 gaatgtccag ctttacacgg cgacgcatcc actacatcca gtgaaacgta acagcggtct
    32401 ggagtacgca aaacccatta aaatcggtaa taatgtttgg ttaggcggag gagttatcgt
    32461 cacgccgggt gtcactctag gggacaacgt agtagtcggc gcaggttcgg ttgtgaccaa
    32521 atcttttccc gacaatgtag tgattgcagg aaatcctgct cgtatcatca agacagtaga
    32581 ggaagaacta acagaagagt ctcttgaaac attacgtcat aagatcgata tgatcgatcg
    32641 agagttgatt gctttattag aaaaaagaat ggatacggta actaaaatag gacaagtgaa
    32701 aaaagaagaa aaccaagcag tttatgatgc aaaaagagag cagcaagtat tggataaagt
    32761 tgttagtctg ctgaaaaata agggatataa ggaaacaata acagatacgt atgttgattt
    32821 gatgaaacac tcgcgcgaat accaaaacaa aatgaaggag gaataagtgt gatcgaagga
    32881 gagacacggc gaaaacaaat catgcaaacc ttggcaaata cagaaaaacc agtgagtgct
    32941 agcaagtttg cgaaaacttt tggagtcagc cgtcagatca ttgtaggcga tattgcttta
    33001 ctacgagctg caggtaaaag tatcgtggca acagcaagag gttatatcct cgaaacagaa
    33061 gaaaccaata ctgggcacat cagtaaaatc gctgtccagc atggaaaaga tcaaacagaa
    33121 gaagaactga gactaatcgt tgaaaatggt ggtgaaatca ttgatgtaat tgtggaacat
    33181 cccctttacg gtgagttagc aggaactttg cacatcaaaa cgccacaaga tatcgattcc
    33241 tttatgagac gttatcaaaa aagtaatgct actttgttat ccgaattaac aggcggcatc
    33301 catctgcata cgatccgcta cccagaaaag catatgctga aaaacatcaa acaaaaacta
    33361 gctgaagcag gaatcctcta cgaaggataa catcgtagct gctacttttt atcctagaaa
    33421 ctattctatc atctctgaga taaacaccca tatggaagaa ataagaaaaa ataagaaaag
    33481 atgcgtatcc aatacacaga attttttgga attgcgattt ctagatgtct atctaaattt
    33541 cgattagtgg agaaacataa aaaagggaag tgcagctttt gagcactccc cttttttata
    33601 aagctttctt gtagcatagt atcgaaggaa cctgccaatt ctctactcga tcaccaatac
    33661 gccttctttt agtgcaaatg gattttgatc gttgatgtgg tcatagaaca tcacaccgtt
    33721 gatatggtcg atttcatgtt gaacgacgat cgattcataa ttcttcaaac gaatcttgtg
    33781 tttttcacca ttcatatcat aataagacac agtgattttg gcatggcgaa caacatatcc
    33841 tggtacttct cgatcaacag ataaacagcc ttcaccttcc cctaaacaag catcttgaac
    33901 agaatggctc aaaattttag gattatacat aacagtactt agagaaggtc catctgcctc
    33961 tgggtcagga cttggtacgt gaacagcaat gattctttta gaaatatcta attgaggagc
    34021 agctaagcca acaccgcctc gtaagtgtag ttcttcagct ttgattggat cttggctgtt
    34081 ttttaagaac tcaagcatct cttttcctaa agagatatct tcttcgctta atggaagaga
    34141 aacttctttt gcaacttcgc gtaaggtcgg atttccttca cgaatgatat catccattgt
    34201 aatcatggaa tatgtacccc tttcttaaaa gactgtgttt caagtctatt ttcgcattat
    34261 agtttaccac aaaaatggaa aagtagtagt aagattgttt gaaaactacc ttttcttaat
    34321 gattaactac ttgattttca acccggtttc aggtaaagta tagctgtgtg ctctaggcac
    34381 atgacctgcc acttggttaa gcgaatcacc aacgttttac tcagtcgcag gggaataatc
    34441 gaaagaggtg aaagaaatgg caatttcaaa agaacgcaag aatgaaatca tcaacgaata
    34501 cgctcgccat gaaggggata ctggttctcc agaagtacaa atcgctgtat taactgaaga
    34561 aatcaaccac ttgaatgaac atgcacgcgt gcacaaaaaa gaccatcatt cataccgcgg
    34621 cctaatgaaa aaagttggtc accgccgtaa cttgttagct tacttacgta aaactgacgt
    34681 tcaacgttac cgcgaattga tcaaacgttt aggcttgcgt cgttaatttt agtcaaaaag
    34741 agtgggattc acatgaatct cacttttttt actcgtatat caattaagta aaattccgtg
    34801 atcaagctag atggactcct actaaccaaa tgaaagctgc tcaaaagacg gctttcggca
    34861 gttttcattt gtttagtagc gtcttgcttt cacgagaagg aaaaggagaa gttatgtcag
    34921 aaaaacaagt attcaaaacg acatggggcg gccgtccctt acaaatcgaa gtcggtcagc
    34981 tagcaaaaca agcaaacgga gccgttttag tccgttatgg agatacagta gtcttaagtg
    35041 cagctgtggc ctctaaagaa gcaaaagata cagacttttt cccattaacg atcaattatg
    35101 aagaaaaaat gtatgcagca gggaaaatcc ctggaggttt catcaaacga gaaggccgtc
    35161 caagtacgga agcaacattg actgcccgtt tgatcgaccg tccaattcgc ccgatgtttg
    35221 cagaaggctt ccgtaatgaa gtccaagtaa cgaacatcgt gatgagtgta gaaacagact
    35281 gctcgccagc tatggcagca atgctaggtt cttctttagc actatcaatc tcagatatcc
    35341 catttgacgg cccaatcgca ggcgtagaag ttggtcgtgt aaatggcgag tacgtcttga
    35401 atccaacagt agaacaagca gaacaaacag atatcgaatt gactgttgcc ggaacgaaac
    35461 aagccatcaa tatggttgaa agcggcgcga aagaagtttc agaagaagac atgcttggtg
    35521 cattgctgtt tggttttgac gctatcaaag agttagttgc tttccaagaa gaaatcgttc
    35581 aagcagtagg gaaagaaaaa atggaagtga ctttactgca agttgatgaa gtattgaaaa
    35641 aagaaatctt tgatgcttct tacgctacaa tgaaagcagc agtaatgact gaagaaaaac
    35701 ttgctcgcga agataatatc gagcaggtga agatcgatat ccgcgaagct tatgctgaga
    35761 aatttgcagg tcatgaagat gaagatcact tgttgaaaga agttaaacaa atcacagaag
    35821 atcttgaaaa agatgtcgta cgtgaattga tcaccatcga taagatccgt cctgacgggc
    35881 gtaaattgga tgaaatccgt ccattgtcat cagaggtcag cttattgcca cgtgtacatg
    35941 gatcaggttt gttcacacga ggacaaacac aagctttatc agcttgtaca ctcgcacctc
    36001 taggagagca ccaaatcatt gatggtttag gggtggaagt cagcaaacga ttcatccacc
    36061 actacaattt ccctcaattt tctgttggtt ctacaggacg tgcaggctct ccagggcgtc
    36121 gggaaatcgg acatggcgca ttaggtgaac gtgcgttagc acaagtaatc ccttcagaag
    36181 aagaatttcc ttatacgatc cgtttagtag cagaagtatt ggaatcaaat ggttcttctt
    36241 cccaagcaag tatctgtgct ggcacattag cattgatgga tgcaggtgta ccaatcaaag
    36301 cgccagtcgc cggtattgcg atgggacttg tttctgatgg tgaaaactat acgatcctaa
    36361 ctgatatcca agggctggaa gatcatcttg gcgatatgga ctttaaagtt gccggtacaa
    36421 aagatggtat cactgcttta cagatggata tcaagattca aggaatcaca gaacaaatcc
    36481 taactgaagc attaactcaa gcaaaacaag cacgtatgga aatcttagaa gaattgactt
    36541 caacgattgc tgctccacgt gaagaattaa gccaatatgc accaaaaatc gaaatgatcc
    36601 agatcgaacc tgctaaaatc aaagatgtta tcggtaaagg cggcgatacg atcaacggaa
    36661 tcatcgatga aactggtgtg aaaatcgata tcgatcaaga tggaaaagta agtattgctt
    36721 cagctgatgc agaaatgatc aaaaaagcta tcaagatcat cgaagatttg accaaagaag
    36781 tcaaagttgg tgaagtttat ctagggaaag ttgtccgtat cgaaaaattc ggtgcattcg
    36841 tcaacttgat caaaggaaaa gatggacttg tccatatttc ccaattagca aacgatcgtg
    36901 tcaataaagt cgaagatgtt gttaaactag gtgatgagat ccttgtgaaa gtaactgaaa
    36961 tcgataaaca aggacgcgta aatctgtcaa gaaaagcaat gttgaacgaa gatggttcaa
    37021 cgaaaaatga agaaaaataa tttaattcat aggaataatg tacttgtgat cgtgaaggtg
    37081 acagggggac aataattatt cgaaaaaagg ggactgtgac aaaagccgtg tcacagtcct
    37141 tttttttcga ataaacggtg ttcaaaagct tgcatctgcg gtaataagtc cagccaagtt
    37201 aaaaacatta ggagctgttt ttatttggct gttcttatta cttgatgcag aacagctttt
    37261 ttacaacctc tccaataaac gatgttcaat cagctgtccc tcgatattag ctcaaaaaac
    37321 ggcaaaatat gaggaactat ttttccgttt gtttctctaa tactcaggtc aaaccgctga
    37381 tttcacaacc tctgattcac ggtgttccag aagcagcttc tacggaaata agctgaacac
    37441 ttttgttaca acttcttttt ttctggagtt tcttggcgca tatttttgga gtccttctga
    37501 ataaagcgta aaataaaagt gagaaatatg gataaaggag ggaaaggaga tgctgaattt
    37561 tttatggtcg ttatttatcg gcggtatatt aggtttgata gctggcgcaa ttttaggaaa
    37621 ggaagtcccg ggaggcgtat ctggaaatat cattatcggt tttttaggta gttggctcgg
    37681 cgaattttta ctaggaccac tgggaccgga actcggcggt ttttatttga taccagcatt
    37741 attgggtgca attttttgcc ttgctcttta ttcatttgtg gcaagacgta tcagagaacg
    37801 tccaaagaaa gaataatttt attcaaataa gttgacactt cagtgtgtta cttggataat
    37861 tagaagcaat ttaggaaagc gggtgtcatg gataagaata tcatctatca ttcaagctta
    37921 cctaaaggat atccatataa caagaaatga gggaaaaacg tggcaacaac gcacaatacc
    37981 aaaaagatat caatgactgg cctgcttgta gcgatgggag tcgtctacgg agacatcggg
    38041 acaagtccgc tttacgttat gaaatcgatt gttgaagata atggcggatt gtcaggaatc
    38101 aatcctgatt ttgttatcgg atcagtctca ttgatttttt ggacattgac tctactgaca
    38161 acaatcaaat atgtcgtgat tgcattgaat gcagataacc atggtgaagg tggaattttc
    38221 tcactctaca cacttgtccg aaaaggtggg aaatatttga tcattcctgc aatgatcgga
    38281 ggagctgcct tactagcaga tggggtattg acccctgctg tgacggtaac gactgcgatt
    38341 gaaggcttgc gaggaattcc gcagtttttt gaccggttcg gtaataacca gaacgtgatc
    38401 gtcattatca ctttagttat tatttttgtt ttattcatgg tccaacgctt tggtacagat
    38461 attgtcggaa aagcattcgg accaatcatg ttcgcttggt ttactttttt aggcgtaatg
    38521 ggattaatga acttcagtca agactggaca gttatccgtg cactgaatcc ttattatgct
    38581 atccagctgc tttttagtgc agataacaaa ttaggcttgt tcattcttgg aaatattttc
    38641 ctggctacga caggtgcaga ggcgctttat tccgatcttg gacatgtcgg caaacgaaat
    38701 attcgtctga gctggcctta cgtcaaaatt tgtttggtta tcaattattt tgggcaggct
    38761 gcgtggttgt tgaatgttta tcaaaaccct gaagcacagc aaatcaagaa cctgaatcca
    38821 ttcttccaaa tgatgcctca aagttggatc gtgatcggcg ttgcttttgc aacagtcgct
    38881 gcagtcattg cttcgcaagc attgattaca ggttcgttta cgctagtttc agaagcaatc
    38941 aagttgaaac tgctgcctcg gttaaagatc atgtatcctg ggaacagtat cgggcaaatg
    39001 tatatcccag cagtcaatct gattttatgg atcgcctgtt ctctagtggt tgtcacattc
    39061 cgaacgtctc atcatatgga agctgcttac ggtctatcga tcactgtgac gatgttgatg
    39121 acaacagcac tgctttactt ttatcttatc caaaatgggc attctcgttg gcttgcatat
    39181 ttagttacct ttttcttcgg tgcgatagaa gtcgttttct ttatctcaag tgttgtcaaa
    39241 ttcttccgag gcggttttgt agccgttctg attggtttga tcatcttagt cgtgatgttt
    39301 atttgggaac aagggaacat tattcgcgaa tcgtcaaccg aggatgtgtc tttgagagat
    39361 tatatcccgc agcttagaga attacgtgat gatacttctt taccaatcta tcagacaaat
    39421 gtggtcttct tggttcctga tatggctgaa gataaagttg gccgacagtt catctattcg
    39481 attttagata aacggcctaa aagagcacga gtctattggt ttgttcatgt ggaagtgacg
    39541 gatgagccat atacgaaaga atatcaagta gatatgatgg acactgattt tattgtccaa
    39601 gtgaatctgt tcttaggttt cagggtccaa caggaaatca acgtatatgt tcgccaagtc
    39661 atccatgatt tgatgaaaca aggccgtttg ccaaaacagc cacaaagata ctctctgaca
    39721 ccagggcgag aagttggcga tttccaattt gtcctgattg atgaagtagt ttccaatgtg
    39781 acaactctag gaaaatggca acgtcaaatc atgcaggcaa aactggcaat caaaaaaatc
    39841 gctacctcgc cagaaacatg gtttgggcta gagtacagcg aagtaaaaca tgaaactgtt
    39901 ccgcttatca ttggaaatac tcggaaaaca tggttgaaag agcggttgtg aaagtagcgc
    39961 tttgacctga actaatgtcg aatgtcagct acttgaacac cgtttatcag aggtcatgaa
    40021 aaagctgtac tgcaacaagc agtaagaacg agcagataaa aacagcttct catgtttttc
    40081 atctgtttgg gcttaatgcc gtagatgcaa gcttttgaat accgttttta tcagaggtca
    40141 tgaaaaagct gtttagcaac aagtaacgca atgattttga agtgataagg agatgtggct
    40201 gaaaaatgcc gcatctcctt ttttattcct aaatatgaat acgcattatt ttcaatcttt
    40261 ttgtagaaaa agggtacaat agaaaaagag aaaggcggga gaatatggtt atcaatttca
    40321 ttattttatt tttgatgatt gcaattactt cattttttgt agcaagtgaa tttgctttag
    40381 tgaaaatcag acgatcaaga ttggaacaac tagaaaagga aaatgtaaag aacgccaagc
    40441 tagctcttca tgttacacac catttagata actatttatc agctagtcaa ttaggaatta
    40501 cgctaaccgg tttgatcatc gggtgggtcg gtgaaggatc tgtcgcggct ttactagaac
    40561 cagtgatcgg taaactacct tttagttcgg ctattagcag tacaatctct gtggcgctgg
    40621 gatttatttt agttacgtat atcgatgtgg ttattggcga actgcttcct aagagctata
    40681 gtatcgtcaa tacggagaag gtcgtcttgt tcgtagttaa accacttcat tatttttata
    40741 aagtaatgtt tccttttatt tgggtattga atcattcagc tgcagggcta gggaagctat
    40801 taggtgtgcg tctcgtatct gaaggagaag agacattgtc tcaagaagag ctgacattag
    40861 tcgcattgaa ttcttatgaa aaaggagagt tgaccaaaga agaatattat tatttggaaa
    40921 acgtgtttga atttgatgat accttggcaa aagatataca agtagaccgt acgtccatgc
    40981 aagtattcga agcttcagaa accgtcaaag aagcgataaa agcttcgatt gaacaaggac
    41041 atactcgcta tccggttatc ttagaatcaa aagacaatgt tttaggttat gtcaccttgc
    41101 cagatttgat caagcaatct tataaagatg accagctgac agtagaacag ttgattgaag
    41161 agccgatcgt aacaactgaa acgatcccta taaaaaaatt attgacgatc atgcgaaaaa
    41221 agggtaagca tattgctatc ttaaaagatg aatacggagg gacaagcggc ttagtgacga
    41281 ttgaagatat tttagaagaa atcgtcgggg aaatccgaga tgagacagat ttggacgaag
    41341 cattgatagc ggaacagtca gatggctctt atatcatctc cggcaaacta acattagatg
    41401 atttccagcg ttattttcat gtagagattc cagagtttga agaaacgaat tttactacac
    41461 ttgcgggctt tgcttctagc cgatataaag aaataaaagc aggaacaatc attgagattg
    41521 catcattccg tttcacggta ttagaatacc agcatgcaca tatcgattat ttcaaagtag
    41581 agtccacgga aagaaaaaca gaataaaaga aaaaaggctg tgacattttt tgtcacagcc
    41641 tttttgttat ctaaaaaacc tgttttcggt aaacgaagaa gatattttca ataaaagttt
    41701 tcatttttag ccgcaacgat ttcttttaat caaggctatc ttgcttctgc atgttctaat
    41761 gtgaaatgtt cctcttcacc catgtgtttc aattgtttca tcgaacgcat ataagagtaa
    41821 agcaacacgg caacagaacc gatccaagct aaaggagaag ctgctgctgc tcctgggtat
    41881 ccccacattc ctgtaagaac gatagctgca aaagaacgca taagcaattc catcataccg
    41941 gcgatcgtag ggatcttgct ttgtccaagc ccttgaagtg tgtagcgtaa aatgaacagg
    42001 actgctaaga tccagtaaag agacccattg atattgaagt aggtttgtgc taattcaaat
    42061 acacgtgttt ctgatgggct aacaaacaat tgaacaaaga aatgaccgaa gaaaatgacg
    42121 atagcacctg ctaagagact aaatccgaca ctcatcagta aagtttgacg taccccttgc
    42181 aagattcggc catattcttt cgcaccatag ttttgtgcag tgaaagttgc cattgcaata
    42241 ccaaatgaca tcatcggctg atttgcaaat tggtcgatac gaccagcagc ggcttgagca
    42301 gctacgacat ctgtccctag actatttagt gctgcttgta acacgatagc accaacagcg
    42361 atgatcgaag attgaaacgc cattggcaaa gcagcattta ggtgtacagc aaactcttct
    42421 ttttcaaatt tgaaatcttt tttgcgtaac tgtaacaaag gcattttttt cttgatatac
    42481 actagacaca gtacgctgga agaaacttgt gcgattactg tagcaatagc tgcaccttcc
    42541 acacccatgc caaaatagat aataaagatc aaatcaagta cgacgttgat gatgaccgca
    42601 atgatcagaa agaatagtgg tgtgcggctg tcaccaagtg cgcgaatgac attagaaagc
    42661 aaattgaaac tgactgatgc aaagatccct aataaaataa ttgaaataaa tgtttgtgct
    42721 tgatcaagta tttcaggagg agtttgcatc aattgaagca tcggacgaat aaacaggaga
    42781 cttaggacag ttaaaatcac agtgacgaca agactaatga caacactagc agcaaaactt
    42841 ttcttcagac cccgataatc ttttgcaccg taacgttgtg cggtaataat ggctaaacca
    42901 gctgttaaac cttgggcaaa gccaatgatc aaaaatgtca ggcttccagt tgcaccaacc
    42961 gctgccagcg catttttacc tagcgtctga cccacgatga tcatatcgat catattgtag
    43021 aactgctgaa aaacatttcc gatcagtaaa ggaacagtga acatcaaaat cagtttagcg
    43081 gggcttcctt ttgttaaatc gcgcatcttt taaactcctt atatctttaa aatttagtta
    43141 gtagtatata gcgtttatcc tgagaatacc aattagaaat caatgataat ttatgaaact
    43201 ccataaaaag aagccaagaa ttgagtcaaa gaatcaacaa cttggcctgg tctgtaaaat
    43261 aagggacatc cacgtttatc tatcacctta atattgtcta atctcacttg gtaaaaggat
    43321 cgtttctctc gtaccgtcat cataggcgta tacttgagca ggaaattggt tcgaataggc
    43381 aaacggcaaa tcaatatcca tttccacatt gcttcctgct tgagaaaaat gcatcgtcac
    43441 ttttccacga ttttcgatca aatcaaaggt taatatattt tctaatggaa tgactccctt
    43501 aagatctagg tcaataataa accatatact gtcaatcaat tcatctggca aacttgatac
    43561 gacaccaact gaagcgtaac ggttgcggct gctatcaaaa ctttcaaaca tctgtttaac
    43621 ctccttcgaa tcaacgaatg ttttattttt ataattaatc ctaggataaa ctagaaatac
    43681 ttacttcaac gagggttcat tctaataaag aatcaggaaa aatgcaacaa taattgaata
    43741 ctttttttca aagtataaat ttttataaag gtacgataaa agtatgcgag gaaaagcttg
    43801 gtaaattagg atttttcgtt tgtaaagcca tttacaaaag tggaagcccc atatgaaaat
    43861 aaacgattag aaataaaaaa ggcgtgttaa aagctgctga cccgccgctt ctaacaccac
    43921 ctgattgttt cagtattatt cttctgttga accgatcact tctggttcgc caccttcacc
    43981 tgtgctttct tcttcttcac tttgagcgac tacagcagcg atttgctctt cactgtcggt
    44041 cacgaatttg taatcgtcgt tttttggaag atcggctact gtaatagaat cacctaattc
    44101 caagtttgtc acgtcaactt caattcgttc aggcaatttg tctggtgtag cagatacgac
    44161 tactgtatac aagttttgag ctaacactcc accagattta gcacccactg attcgccaac
    44221 aagaacgact tctgtttcga cttctgtttc ttccgacatg tttacagata gaaattctgc
    44281 atgttcgaaa tgattggtaa aagtgttcgt ttggatcttg tgaaccaatg tattgacttt
    44341 ttgtccatcg atgtccatcg tgatgactgt gttcgctcca tgttcacgca acaatttgct
    44401 tagtgtcaaa ccatcgaatg agataggggt actttctact ttatacccat aaacaacagc
    44461 tggaactttc ccttcgtgac gaagtttgtt tcttaatgaa cggggacgta cttctctttt
    44521 acttacttct aatgatactg acataaccaa aattcctcct taaaatgtga ctgtctgctt
    44581 tggtaacgga cagattttat ttaagtgaat tctaaaggct aatctcgtgc acatcatcga
    44641 aggcagggcg cttaaaaaag cgcaaaagga gagatgcgcg catctcccct tagaaagtca
    44701 ggattcaact tttctccacc aggtcattac gctgtgtatg agaaatccaa ttcactttac
    44761 tatttaaccg taacgtgaac tgttaattaa gtcaaggaat aactatgatg atgtatttgc
    44821 aagcaagaat attcaaggta taattaatta gtagtaataa gaaaggaaac agcatgcgtt
    44881 tagataaatt aatagaagaa aaattagaaa cgacacgcaa ggaaatgaag cggctgtttg
    44941 ctttgaagca agtgatgata gatggcacag tcgaatttcg acaaaatcga aatgtagata
    45001 gtttactgca tcaaatcgaa gtagcaggtg aacacttaga aacaaatgag tcctattatc
    45061 ttctcaataa acctgaaaaa gctgttacag ctgtatcaga tccagaaaag acgacagtaa
    45121 tcgatctgat tgcaagtgcc gatcgtttcc aaccattata tccagtggga agactagata
    45181 gagatacaac aggactattg ctgatcactt cgaatggaca attgggatat gaaatgctac
    45241 ttccagaaaa aaaggtttca aagacttatc aagtagttgt gaacgaaagg gtgacaccgg
    45301 cagacgtaac agcatttgaa aatggaatcg tattcgctga tgggtatcaa tgtaagccgg
    45361 ctgatttaaa aatactcaaa gcagacaagc accaaagtac ggttttattg acgatccaag
    45421 aaggaaaatt ccatcaagtc aaaaagatgt tcttagccca aggaaagaaa gtgaccgcat
    45481 tgaaacggct aagcatggga ccattggaat tagatgaaca gctaggagta ggcgagtatc
    45541 gatcgttgac attagcagag atgaaaaagt taagtattta ttttaaatag gaggtcaaaa
    45601 agatgaaata taaaacttta ttgtttgatg tagatgatac attgttagat tttcaattaa
    45661 ctgaagccaa tgctttaagt gctttgtttg cagaacaagg aatcacattg acaccagaaa
    45721 tcgaaaccag ctataaggct ttgaatcatc atttatggca ggagtttgaa aaaggcagac
    45781 tatcacgaga agaaataata ggcagtcgtt ttgggttact tttccagcaa tttgggaaaa
    45841 cagtagatag tgatcaaatg gaaaaacgct accgccacta cttgaaccaa ggtcatgatc
    45901 ttgttccagg aagtctagaa atcctgaaaa aggtccatcc gcatgctgat ctttatattg
    45961 tgacgaacgg tgtgtcgcac acgcaacatc ggcgattaac agatgcagga atgcttgatt
    46021 acttcaagga tatctttgtc tcagaagctg tcggagcgca aaagccgatg aaagaatttt
    46081 ttgatcatgt cttttcccac attcctaatt ttgataaaaa gcaaactgtg atcattggtg
    46141 attctttgac ttctgatatc aaaggaggaa atatggcagg gatcgatacg atttggttca
    46201 atagaaataa attaccagaa atcgaagaaa tccagcctac ttatcgaatc gattcattag
    46261 aggaacttta ttcattattg gaaattgaaa aggattaatt ttcagaaaaa tatagcattt
    46321 tcgtgttttt tcgctataat agattagaat gaaaaaacgg atacgaaaga ggttttagtc
    46381 aatgacaaaa agcaagccaa ttatcattgg tgtgacgggt ggatccggaa gcggaaagac
    46441 aagtgtcagc cgtgcgattt tcaacaactt cccggaccat tccatcatga tgcttgaaca
    46501 agattcttat tacaaggatc agagccattt gagttttgaa gaacgattga acacaaatta
    46561 cgatcaccca tttgcctttg ataatgatct gctgattcag catgtaggcg acttactgaa
    46621 ctataaagcc attgaaaaac ccgtgtatga ctatgtagcg catacaagaa gtcaggcaac
    46681 gatcattcag gaaccaaaag aagtgatcat tctagaagga atcctgattt tagaagacga
    46741 acgtctgcgt gacttgatgg atatcaaagt atacgtagat acagatgatg acattcgtat
    46801 cattcgtcgt atcaaacggg atatggaaga acggggacgc acattggact ccgtgatcga
    46861 acaatatttg acagttgtta aaccgatgta tcatcaattt atcgaaccaa cgaagcgcta
    46921 tgcggatatc attgttccag aaggcggaga aaaccacgtt gctattgatt tgattacaac
    46981 aaaagtagct agtttcttaa accataaata gtgcgcagcg aaacagttga acggactgcg
    47041 accgtttgaa aagcaaggat tctgcttttt gaacagtcac cagccaactg tttttttatt
    47101 tataacaaga ggttgtgaaa acagcatctt gacctaagta ttaaaaagaa gaaacggaaa
    47161 atagctgttt atattttacc gttttttgag ctaataccga aggtcagctg attgagcacc
    47221 gtgaagtaga ggttgtaaaa aagctgtctt tgcatcaagc gataagagca tccaaataaa
    47281 acagctcctc acgtttttcg ttgggttggg cttattatcg tagatgcaag cttttgaaca
    47341 ccgtttaacg agaggttgta acagaagtgg tcagatgcaa taaataagaa gaaacttacg
    47401 aaaattattt ctcgaatttg tgtgagattt cgacttattt ttttgaagaa gctcttttgt
    47461 cgcaccccc
//
LOCUS       DBBGSZ010000020        42995 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.020, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000020 DBBGSZ010000000
VERSION     DBBGSZ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 42995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42995
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.020"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            214..498
                     /locus_tag="ACIZE5_001505"
     CDS             214..498
                     /locus_tag="ACIZE5_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HGC6108653.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(779..1198)
                     /locus_tag="ACIZE5_001506"
     CDS             complement(779..1198)
                     /locus_tag="ACIZE5_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HGC6108654.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(1200..1784)
                     /locus_tag="ACIZE5_001507"
     CDS             complement(1200..1784)
                     /locus_tag="ACIZE5_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HGC6108655.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(1831..3306)
                     /locus_tag="ACIZE5_001508"
     CDS             complement(1831..3306)
                     /locus_tag="ACIZE5_001508"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HGC6108656.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            3487..3798
                     /locus_tag="ACIZE5_001509"
     CDS             3487..3798
                     /locus_tag="ACIZE5_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108657.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(3913..6249)
                     /locus_tag="ACIZE5_001510"
     CDS             complement(3913..6249)
                     /locus_tag="ACIZE5_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HGC6108658.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            6391..7059
                     /locus_tag="ACIZE5_001511"
     CDS             6391..7059
                     /locus_tag="ACIZE5_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC6108659.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERVGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            7062..8105
                     /locus_tag="ACIZE5_001512"
     CDS             7062..8105
                     /locus_tag="ACIZE5_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC6108660.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(8342..9223)
                     /locus_tag="ACIZE5_001513"
     CDS             complement(8342..9223)
                     /locus_tag="ACIZE5_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGC6108661.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            9382..10110
                     /locus_tag="ACIZE5_001514"
     CDS             9382..10110
                     /locus_tag="ACIZE5_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HGC6108662.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            10266..10583
                     /locus_tag="ACIZE5_001515"
     CDS             10266..10583
                     /locus_tag="ACIZE5_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGC6108663.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            10576..11184
                     /locus_tag="ACIZE5_001516"
     CDS             10576..11184
                     /locus_tag="ACIZE5_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HGC6108664.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            11239..12030
                     /locus_tag="ACIZE5_001517"
     CDS             11239..12030
                     /locus_tag="ACIZE5_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HGC6108665.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            12168..12656
                     /locus_tag="ACIZE5_001518"
     CDS             12168..12656
                     /locus_tag="ACIZE5_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HGC6108666.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            12707..13579
                     /locus_tag="ACIZE5_001519"
     CDS             12707..13579
                     /locus_tag="ACIZE5_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGC6108667.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            13755..14117
                     /locus_tag="ACIZE5_001520"
     CDS             13755..14117
                     /locus_tag="ACIZE5_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HGC6108668.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            14126..14878
                     /locus_tag="ACIZE5_001521"
     CDS             14126..14878
                     /locus_tag="ACIZE5_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6108669.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            14892..16694
                     /locus_tag="ACIZE5_001522"
     CDS             14892..16694
                     /locus_tag="ACIZE5_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6108670.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            16971..18011
                     /locus_tag="ACIZE5_001523"
     CDS             16971..18011
                     /locus_tag="ACIZE5_001523"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGC6108671.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(18063..20207)
                     /locus_tag="ACIZE5_001524"
     CDS             complement(18063..20207)
                     /locus_tag="ACIZE5_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HGC6108672.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(20564..21937)
                     /locus_tag="ACIZE5_001525"
     CDS             complement(20564..21937)
                     /locus_tag="ACIZE5_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC6108673.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="ACIZE5_001526"
     CDS             complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="ACIZE5_001526"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HGC6108674.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="ACIZE5_001527"
     CDS             complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="ACIZE5_001527"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HGC6108675.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(23385..24398)
                     /locus_tag="ACIZE5_001528"
     CDS             complement(23385..24398)
                     /locus_tag="ACIZE5_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HGC6108676.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(24479..25078)
                     /locus_tag="ACIZE5_001529"
     CDS             complement(24479..25078)
                     /locus_tag="ACIZE5_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HGC6108677.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            25264..25965
                     /locus_tag="ACIZE5_001530"
     CDS             25264..25965
                     /locus_tag="ACIZE5_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6108678.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            25975..28686
                     /locus_tag="ACIZE5_001531"
     CDS             25975..28686
                     /locus_tag="ACIZE5_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGC6108679.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            29137..30765
                     /gene="treC"
                     /locus_tag="ACIZE5_001532"
     CDS             29137..30765
                     /gene="treC"
                     /locus_tag="ACIZE5_001532"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HGC6108680.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(30825..32006)
                     /locus_tag="ACIZE5_001533"
     CDS             complement(30825..32006)
                     /locus_tag="ACIZE5_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGC6108681.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            32258..33781
                     /locus_tag="ACIZE5_001534"
     CDS             32258..33781
                     /locus_tag="ACIZE5_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HGC6108682.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(33850..34578)
                     /locus_tag="ACIZE5_001535"
     CDS             complement(33850..34578)
                     /locus_tag="ACIZE5_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HGC6108683.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(34591..35871)
                     /locus_tag="ACIZE5_001536"
     CDS             complement(34591..35871)
                     /locus_tag="ACIZE5_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HGC6108684.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(36012..36614)
                     /locus_tag="ACIZE5_001537"
     CDS             complement(36012..36614)
                     /locus_tag="ACIZE5_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HGC6108685.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            36859..37065
                     /locus_tag="ACIZE5_001538"
     CDS             36859..37065
                     /locus_tag="ACIZE5_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108686.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            37377..38096
                     /locus_tag="ACIZE5_001539"
     CDS             37377..38096
                     /locus_tag="ACIZE5_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HGC6108687.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(38177..38860)
                     /locus_tag="ACIZE5_001540"
     CDS             complement(38177..38860)
                     /locus_tag="ACIZE5_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HGC6108688.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            39078..41264
                     /locus_tag="ACIZE5_001541"
     CDS             39078..41264
                     /locus_tag="ACIZE5_001541"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HGC6108689.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            41610..42020
                     /locus_tag="ACIZE5_001542"
     CDS             41610..42020
                     /locus_tag="ACIZE5_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGC6108690.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            42034..42390
                     /locus_tag="ACIZE5_001543"
     CDS             42034..42390
                     /locus_tag="ACIZE5_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGC6108691.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT        14022 a         7563 c         8595 g        12815 t
ORIGIN      
        1 aggaagaggt tgtgagcctg ccgtttaact ctgagtcaca aggagcaatt tcaaaaaaca
       61 gcttctcatg tttgttgact attgtgactt gtgaccgagg agttggcagg agaacaccgt
      121 ttattcgaaa aaaggaactg cgacaagact tttgtcacag ttccttcttt tttttgctat
      181 gctatactag atgtaaaaaa taggagaaat aaaatgaggg aaatttattc ttttgaatca
      241 aaaatctatg cttccgaagt cggcaagggc ggggcatata ttatttttcc gtatgatata
      301 agaaaagaat tcggtgctgg aagagttaaa gtccaagcaa cttttgacaa tgtgccgtat
      361 gaaggcagta tcgtgaatat gggcgtgaaa aatccagatg gttcagtctg ctacatcctt
      421 ggactacgaa aagatattcg taaaaacatc ggaaaagaaa tcggtgatat tgtagcagtt
      481 acagtgaagc aaaaataaaa gaggttgtga caaaagacgt gtcacaacct cttgataaac
      541 ggtgttcaaa agccagtttc tcggtagtaa gtcaaattta tgcaaaaatg tggaaaccca
      601 tgtttacaaa atttttctta ctactcgaaa cgaagcggct ttatcacaac ctcttgataa
      661 acggcgttca atcagctgtc cctcggtatt agctcaaaaa cggcaaaata tgagaagcta
      721 tttttccatt tttttctctc atactcaggt cataacgctg atttcacaac ctcttctttc
      781 ataatggttt ttcaccatct ttataataaa ctggttcttt gatatggaaa tctatttttt
      841 ccaaccaatc taaaatcttg taacctaact cttctgacat cggaaaagag gcgttgattt
      901 gtgcattgga gatatggtca acatggatac cggaagtgat cgtacaactt cccggaacgg
      961 cagttttgat gatcacagct attttttcgg ctaagacatc gtctttatgg aaccgaccat
     1021 cgtggctagg gaaacgtaca gtttgcatct ctgtatcacg agaaaatgta gtgactgttc
     1081 cgatatgtgg tgtatctccg cctgttaaag tgatcaataa gtctttaccg attactttaa
     1141 cagcagcttg gatcgtgaaa cctagtttgg ttacttcaac tatcgtttct ttttccatat
     1201 taatcaccct gccaacgttt tgaatgctca tttacaattt caaattgatc caaaagtttc
     1261 attgtatggt gattaacaag atcttggatc gtttgaggct gattataaaa agcaggaatt
     1321 ggtggtatga tttgcacacc tagtcgtgct aatttagtca agttttccaa gtgaatggca
     1381 tttaatggcg tttcacgagg aacaatgact aactttcgtt gctccttcat tgttacatca
     1441 gcagcacgtg caatcaggtt gtcgcctaaa ccaacagaga tacctgcgac tgttttcata
     1501 cttgccggta cgatgatcat tccatcggtc aaaaatgatc cgctggcgac agcagcacct
     1561 aaatctttgt ttgaataatg gtaatcaaac aggctttcga attcagttag tgataagtcg
     1621 gattccagct ttaagttctg ttttgcccat ggactgatga ttccgtgtgt ttctatcatc
     1681 ggatattctt ttagtttctt cactaggttg atggcataaa tggtgcctga agcgccactt
     1741 acaccaatca cgattttttt cttccgttgt gccaattgtt ccattttccg cactcctttt
     1801 tatgatgtca aaacagttgc agatcattca ttatttcaaa tatttttccc aatcttctac
     1861 ttcttggaat tttgcacgta caaaatgttc tttcatatcg aaaggaactg taccgtcaaa
     1921 gatagttttt gcacttatcc cacggaaacg aatagagcca ggattatatt ctggtaattc
     1981 tgatgggtcc aatggatggt tcctcattcc tgggatcacg atgatatctt tatctccttg
     2041 gaaacgagtg ttgaaagtcc aaactacatc gttcatgtcg aaaatatcaa catcttcatc
     2101 gactaaaatg actgtcttca attctttgaa ggctgataaa gcaagaatag ctgcttgacg
     2161 ctgaatacct tcatccgctt cgttttcttt acggatttgc atgatggtca tcaatttacc
     2221 accacctgca ggaggattgt agacatttac tacttttcct ggaatagctt tatcgaccaa
     2281 ggcaagaata cttgcttctg taggaatacc ggccatagat acgtgttctt cactgggacc
     2341 aatcgttgtt tgcatgattg gattgtcttt tcggtgagta actgctttga ctttcactac
     2401 ttgtacagct ggattagcat ccccagtata gccaggaaat tctggcattg cttttcctga
     2461 gttcgtgttg atatcttctt gcattgtttc atttggcatg atttctgctt caatgatgaa
     2521 ttcagcacga gcaataccca cttcatcgac tgctatacca tcaacgattt gaataggttc
     2581 gttacgcaaa gctcctgcac accatagttc attgtagcca agtggagtgg taggtggttc
     2641 gaaagtcgtg ccaatggcaa ttgctggatc taaaccaata ttgatagtga taggcattgg
     2701 tttattcaag gcttcgaatt gtttttggaa gtgaccaatg tggcgtccgc caggcatgat
     2761 gtacataccg atcgtatctt tatcttctag aaccatacga tggatcgtta catcgctcat
     2821 tgttttttct ggatctgatc ctaagactac acccattgtg atgtatggac cagcatcttc
     2881 aggagtattt gtaggtgcag gcaaaatgtt gcgaatatcg aagtctgcat cggtagctag
     2941 atgaacgact tcttgtgctg gagcgtctgc tttgtctact ttcacaggtt tgattggatt
     3001 ttctacagcg tctttcaaga aacgaccaag tgttcgataa tcatggtgca aaatttcacc
     3061 tacacgttta cgactagcca ttgttccgat gttcacacgt gtgccgggga aacctttgat
     3121 attgttgaaa gtcatagctg gtccttcttg agtcggacgt tttactgtac cgccagcacc
     3181 gatataacgg taaacaccag ataattctgc ttcaggatcg atttcaatat ctgtttcgtg
     3241 atattgacct ggaagtgttt ttagttcttc gatgactttt cttaaatcat acggttgatc
     3301 tgtcatgaga gattcctcct tagttgtctt tacctatcta tagtaaaagg tgaaaaagag
     3361 gaaaacaatt caacttgttc ggtaaagtat tctacaatgg aatggatgcg tttttttgat
     3421 aatagaataa actatgatat acttatcact aaaagaaagc gcatacttag tgttggagga
     3481 aggaaagtga aaaaaatgga ggagtcattt cctaaagcag taaaagtgga aaatatagcg
     3541 aatattttga aagttacatt tgaaaacgga gaagtaaaat acgtgaaatc tcattggaca
     3601 gaagagataa ccgatgcctt gcaatttgga aaaaaaggaa gaggaaaaag aaaaaatctt
     3661 ctcgcacttt ctcgtaatat gtggattggg actgaagtaa cgattgaagc agatggaaca
     3721 gtattcataa atggaaaaga caggtatacg ccagaagagt tgtggtacaa aggaaagaaa
     3781 agtataccag aattataaaa aataattaaa aaaaacagcg cgaaacaagg aacatattac
     3841 ttcctcgttt cttgctgttt tctactattt cagcgctctt atgactcaaa tctaaatgtg
     3901 gttgtcacaa ccttattctg cacgcaaagc gatagcggcg tcttttttcg ctgccattcg
     3961 tgcaggaaga tgaccgccaa gcatcgtcaa tatagtagag acgatcacta gaataatcgc
     4021 atggacagga tttagttgag caacattttt tagatccgtc atgttgtata agatgctatt
     4081 gatagggaac gtagctagcc atgcaataaa cacacctaat atcccagaag aaatacctaa
     4141 aatacacgtt tctgcgtcaa atacgcgagt gatgtctttt ttacgtgcac ctaaagcttt
     4201 tagtacaccg atttcttttg tccgttcaat cacagatgta taagtaatga tactgatcat
     4261 gatcatactt gttactaaag agatccctgc aaaagcaata aggacataag tgatagcatc
     4321 catcaatccg ccagtcagtt cagtcatcgt tccagctaaa tcagtataaa tgattttatc
     4381 ttcatctgat ttgcctttat tgtaatcatc tagataatcc aagatctttt ctttgtcttc
     4441 aaaattgttc ggataaatca tgatacttga aggcaagctg tctccaccta aataactaag
     4501 caatgtttgt ttggcatttt cgtcaacttt ttcagtagtt aagacattta caccactgtc
     4561 tctttgagct ttgacgattt ctgattcttt gttttcgttg acgatttgag tcgttaattg
     4621 atcgctataa gcgattcctg gagataagag attcattgta gaagaagatt tcacgcgtag
     4681 gatccccgag atcttcaatt catcagaagc attctgatac atcgcatcat aatctgtatt
     4741 agggataaaa ttcccagttg gaagttttgt atagtaagta ttgttgttta ctaatttgaa
     4801 tgttgtacca acgatatcat caaaatcaag tttttcgtct tctttcacat caaatccaag
     4861 attcttcaat gcgttgatat tagtattatt attgccgtct acgatcagca cgacatctgt
     4921 tgctgaggct ggataacttc cggcaagtaa agaataattg tcttttaaaa agttttcttt
     4981 gctagtgtca agctgtgtag ggaaacttga cactcccaca cctgtcattg ctgacatcgt
     5041 actagataaa gaaagagatt ccgtatcagg attttgattc gagaagctga caggctgtac
     5101 tttgccattt acatcacgta aaagattgat tcctgtagta cgggtaaatc cgatattatt
     5161 acttaagtta ggatcgatgt ctgttacgta atcgacgtat gtttgatcaa tcttattcgt
     5221 gtgctgtgct ttatcttctt cgctgacttt tgcagtaatc gttttgctgt ctggataatc
     5281 cgctttgctt gcacccaatc cggcatcgtc acgagtctgg ttagtcgtta ccttagaaat
     5341 agtaatcgga aatttcgcca tcgtttcagc ttgcgtgtta tcgatttgtt tttggaatcc
     5401 agaagaaagg gacagaacga tcgcgattcc gatgatccca atactggaag caaaggaggt
     5461 caagaaagta cgtccttttt ttgttcggat attgttgaag gaaagcttta acgctgtcca
     5521 aaaactcatc tttgttctgc gtaagttaaa ttgatcatct tttggtcgtt cgatgtgagg
     5581 atgggaatct gttaagatct taccatcaga aaattcaatg attcgatctg cgtattgatg
     5641 ggccagttca ggattatgtg tgaccatgat cactaatttt tctttcgata actcttggat
     5701 caattccatg atctggatac ttgtttctgt atctaacgct ccggttggtt catcgcacaa
     5761 aaggatatct gggtcattgg ctagtgctcg agcgatggcc actcgctgca tttgtccacc
     5821 agataactga tttggctttt tatgcatatg atttgtcaag ccgactcggt gcaatgcatc
     5881 ttctgcccgt tttcgttttt cgtctttaga aacaccactt aatgtcatcc caagttcaac
     5941 gttttcaata atgcctagat gaccaatcaa gttgtaactt tgaaaaatga aaccgataga
     6001 gttgtttcgg taggcatccc agtcactgtc cttaaagtct ttagtagact ttccgttgat
     6061 taccatatca ccggaatcat aattatctag tccaccaatc acattcagca tagtcgtttt
     6121 accagaacca ctaggaccta aaatcgctac gaattctttt tgtctgaaag cgacagacac
     6181 accatccaat gctttggtgg tggtttcgcc gactttataa tattttttta tatcttttaa
     6241 ttgaagcata atcacccttc tcccgtattg aaatattcgg tatactaata agtatatcag
     6301 aacaatgatc gtagtatacg aaataaatgt taactgaaga tgaactacaa gaaaaaatct
     6361 agaaattttt caaaaaacag agggagatca atgaatcgta ttttagtagt agaagatgat
     6421 ccgcaattac agttgcttta ccgttctgtg ttggaacgag tgggcttttc agtcatcacc
     6481 gcattgaatg gagaggatgc gctgaaaaaa ctagaagcga cacgtataga attaatcatt
     6541 acagatatca tgatgccgaa aatggatggc tatgacttgc tagactcatt acgtagcacc
     6601 agatttgaca cacctgttct aatgattacg gcaaaggccg attttgagga taagaaacgc
     6661 gggttcaaat taggagcaga tgattatatg acaaaaccca tcgatgtcaa tgagatgatc
     6721 ctacgtgtgg aagcattgct tcgacgttca aagatcaatt acagcagtag cttgataatc
     6781 ggacaaacaa aattagagct agatgcttat acagtgttac aagatcagca ttcgttgatt
     6841 ctgcctcaaa aagaatttct gcttctgtat aaattactgt cttatcccaa caagatcttc
     6901 actcgccaac agttgatgga tgatatttgg ggattagata cgaatacaga agaacgaacg
     6961 atcgatgtac atatcaaacg tttaaggacc cgttttgaaa agacggaaga ttttcaaatc
     7021 atcacagtac ggggactagg ctataaggcg gttatttaaa gatgaaaaaa aagctatttt
     7081 cacaattatg gatctatttt gctagtattg tcttcatttc gatcttagtg acactgctgt
     7141 gttttctcgg ttttattttc ttattgtctc gacattctat ctcgcctgct gaatcggctg
     7201 gaaaaccaac gttatacccg ttattcgtct ttgcggggtt cagtatggtc gtgggtacag
     7261 gaatatcgat ttttgttggg cggcgtatcc tgcatccaat cagtgcgcta gggacaaata
     7321 tgagtctggt agcaacggga gatttttcga ttcgaatgga tgaacagcag aaagtagcag
     7381 aagtacagca actgtataaa gatttcaacg ttatggtcca agaactcaat agtatcgaga
     7441 cactgaggaa tgactttgtg tccagtgtat cccatgaatt caaaacacca ctagcaacaa
     7501 tccaaggata tgttcaattg ttacaagccc caaatctctc tgacgaagaa cgccaaatat
     7561 ttttatatcg gattatcgaa agtatcacgc agctttcaca attaacagag aacatcttaa
     7621 aattgaacaa actggaaaac cagcgtatcc aactggaaaa gaaagagtat cgattagatg
     7681 aacaaatcag agaagtaatc gttttttttc agcctaaatg ggagaaagaa cagctagaat
     7741 tggatatcga acttgctgca gtaaattaca caggcaatga agagtttttg taccaagtgt
     7801 ggctgaatat catggataac gccataaagt acaatcaaat caatggacag attcatatca
     7861 aactatttga gacagccaca gagattgtac tggaagtgac cgattcaggt gtaggaatga
     7921 atgaagagac cagagatcga atgtttgaaa aattttatca aggagataca agtcgtcaaa
     7981 tttctgggaa tgggctagga ctttcactgg ttaaaaaaat tctagaactg catgatggac
     8041 gtattgatta tagcagtatc gaaggagtag gaacgacagc aatgatacgg ttaagtaaac
     8101 aataggaaaa agaataaaac ccctaaaaat tctattgaag gtttttaggg gtttttagtc
     8161 gtttttttgt gattagggaa atgttcttac ggttcttttg gcataaaaat cgctgctttc
     8221 ttattgaact acgagaaatg ttagaggtgt cattgaaaca aggacatgat gcaagaaaga
     8281 gagcgaaagt catgcgtcgc tctctttttt tgggtggata gatggacaga aaatgtaggg
     8341 cttagttttc ttcttgattt aaatactccc aaaatgtatc tgaagccaaa gaatgctcac
     8401 cgactttacg agtaaatgca agataactct ctgttgttgg agaaataggg agaatcacag
     8461 tattttcttt taatagattc ttgactgttt tttccataac aatagcaatc cccatgtcat
     8521 ttgcaatcat attgatgatc aagtcgattc ttgctccttt ataagagatt tttggttcaa
     8581 atccagcttc gcgacacaga tctagtacag gttgatacaa gttcgtagtg gggccaagga
     8641 gcaaaaagtt ctcctttttc agttcgctta gatccaattt ctttttacta gctaaaggat
     8701 gatttttagg tagaactgct acaaaatcgt ctgtttcagt aggcaaccac tcaatcgaac
     8761 ttggtggggc ctggaaactt ctagcaaagt ggatcgtgtc actatgttca ttggcgtcat
     8821 tgtaagttaa ttcgacactt tccacttctt tcaactggac tgtaaattca ggatggcgtt
     8881 tcaaaaactc ggtgattttg gaaaaacctt tataattgat cattgtcggt atcgttaaga
     8941 tatttaatga aagattgttg tctttcgtat aggtttcaag cacttcttgc atagcatggt
     9001 attgttctac gacatttttt acatatggga gcaataagct tccagcttcg gtcaattcga
     9061 tttttctatg ggcgcgttcg aataatttga cgtctaattc tgtttctaac gaaagaatct
     9121 gtttagaaat atttccttgg gtggtgaatt gtcgatcagc agttttggtg aaattcattg
     9181 tttcggctaa atcaagaaaa acttcgaatt tatggatatc catcatattc ctcctactta
     9241 ttccaataaa gaatacttta acacaaaaaa tgaattggtg taatcttctc tgtctgttac
     9301 aatctttctt gcagcgaaag caataattac agaaattttt ctgatttttt tcgcttcgta
     9361 gaaaaagaga ggagtttttt gatgccaact ggagttttga tcaatgtagg ttccgttttg
     9421 tttggcggac taattggcgg attagtagga aataaattaa gtgaacattt taaagcacag
     9481 ctgacgatgg tttttggtgt gtgttcgatg gggatgggaa tctattccat tgcgccgatg
     9541 aaaaatatgc cggctgttat ttttgcttta gtgataggaa cagcgattgg tttgattgtt
     9601 catttaggta atgggataaa taagggggct gcgctgatgc aagtacctat ttctaaaatc
     9661 ttccctagtg aaaagcttgg tatgacccac gatgaattta tcagcacatt agtgacggtc
     9721 attgttctat tttgtgcaag tggtacgggg atctatggaa gtttagattc tgggatgaca
     9781 ggagacagta cgattttgat ttctaaatct gtccttgatt ttttcacagc agctattttt
     9841 gcgtgtaatt tagggtatgt cgtttctgtg atagcaattc cccaattcat tattttttat
     9901 attttgttct tattggcaaa atttatttat ccattgacta caccagacat gatcttagat
     9961 tttaaagctt gcggcggatt cttgatggtc gctaccggtt ttagaatgat caacgtgaaa
    10021 atgttcccag tagctgacat gatacctgca atgatcgtta tcatgccact gagctggatg
    10081 tggacaaatt ggattatgcc actgttataa taaaaatcaa agagaagcca ttttttgctg
    10141 actaaaaagg atcaaatctt ttagtcagtt tttttgtatt tgacaaactg attttgaaac
    10201 tatattatat gttgtataat atagattgaa ataaaatatt acacttgaga atagaaggtg
    10261 acgtaatgca catccagatt ccaactgttc ttcttgatgg tactgtgcta gcagcattaa
    10321 gcaaggaaga tatgtatggg tatgccttaa caaaaatcgt acaagaaagt ctctctgtca
    10381 gtgaatctac actatatccg gttttgagaa gattgaaaaa agaaggatat cttgagacct
    10441 atgatgaacc ttttgaaggc agaaaccgtc gatattactc gttgacacca atgggaagtc
    10501 gtcatttaga agaaattatt gatgaatgga ttgtttttcg agattcttta gaccggttat
    10561 tggaggagag cacaaatgaa tgaatatttg aatgaagttg tggatcatct tcaagaaatt
    10621 cctgaagacg atcgttttga tttgatccag tattatgagg aatatttttt agattctgga
    10681 aaaacattag atcagatcat tgatgaatat ggtacaccaa agcagtttgc cttaaaatta
    10741 aaaatcagtt acttttcaga agaagaacaa gcagaaaacg agttagtgaa aaatccaaaa
    10801 agacaaattc gcctgatttg gttaatcatt atcggtttat ttgcttctcc tgtcctcatt
    10861 ccactagcac tggggtttat attggttatt gggggactat tggttgcttt actagcgctc
    10921 atttttagta tctatgtttt atgtatcagt atcttaggtg ttggcctatt catgatcatc
    10981 tcaggaatca gtgtgtttgg acaatcgatt ctgagtggat tattctttat cggtgtcggt
    11041 ctgttcgcca caggaagcgc agtatttatt tcgccactgt tgctgaaagg aacaaaaggg
    11101 cttttttatg tcatgatgaa ctttgttaaa tggatgggac gacgttttat tacaaaaaga
    11161 gatctgcatt cagcgggcgt ttgaaggagg acacataaat tgagattgaa acattttttg
    11221 attaccggta ttggtctgat gcttactggt ggcctcctag caggtgcaac ttatacatta
    11281 ggcgctcaaa agagtctgac ttgggataat ggtcctcggt tgatcgatat ggttactgag
    11341 acaaaaaaaa tcaaggatgc aaacaaaatc gtcatccatg cagaaaatca aacagtttcg
    11401 gtcatacgcg gattggattt tgagataaaa acgacttatg ataagacaga aaagccagaa
    11461 ataaaggaga aaaatggcgt gttgactgtg aatgcagtca aaaaatcaac aggtgcaatc
    11521 attagtttag aagacacaag tgcacaaatc actattgttg tccctgcaga tcatgaatta
    11581 tctgaattga caatcgaagg gaataatagt gcaattgata tcaacgaagt atcaatcaaa
    11641 aaagtgaata ctaagacaca tgatggctgg gtatcgttca atgaatttac aggaggaaca
    11701 ataactgcga aagatgaatt aggctcactt cgattagatg aggccaatgt ggataacttg
    11761 atcgtcacag gtgaaaacag caacttccat ctagaagaca gtttgatcag caaagaagga
    11821 aaagtcatcc taaacggtgg caatttatct ttgcatgaga tggaaaacag tggctatact
    11881 atccaaacgt ctggtgaatc ttatattgaa aaagactacc agccaataac aaatactttg
    11941 ttagaacaag gacagaaaaa gctaaagatc actgctaaag acacatcgat caatattacg
    12001 acggatcaag aggacaatga aacagattga tcctgtactc aactggatat tttaagaaaa
    12061 aacagcaaag atccttccaa tctttgctgt ttttcatcgc ttaacgcaca taactatagt
    12121 aaaataagaa agaaaatatc taaaaagaaa acagggtgaa agagtatatg aaggtagaag
    12181 aaggtcaaag agaaaagtta aaaacagaaa tggaaagatt acatacttat atcactcaac
    12241 taagccaaac cttctatgat ccagacaaag aaaaagtgat ggttaattac ccgaacaatt
    12301 cagaaggtcg ccaattagag caagtgtacc atgaagtttt caaacattta ttgacggtga
    12361 agaaagagct ggattattat tctttaccga ttatcgatac aggaatattg aagtatgatg
    12421 ggaagaagga acgatttatc tttaaatctg ttcgggaaga tttgcctctt tcagcaggga
    12481 tggatctaga ggtcttggta gaagactatt ttacagaaga aaagcactgg gttcgaacaa
    12541 aattggatta tttaccgcag gcagccggag ggacacaggc aagcggttgg tacatcactg
    12601 aagacaaaga gttagaacta gaaggtgtaa tggcgcgtat tcgaaaaaaa aattaaaaaa
    12661 gtaacattag atatttattg aaggataaag gagcgcagga agtagcatga gagaaaaaag
    12721 agcattttat atcaatggtt atgcagggat tgtcggattg gtcgtattag ctttagttgg
    12781 attgtttttc ttctatttag gtatgtggca agcgaaagtt tgggcacttt ttttaagtat
    12841 ttttctttgg ttgatcacgt tattgttgtt aagttcggca actgtagtca gtcctaatca
    12901 agcaaaagta attttgtttt ttggacaata tttaggtacg attcgagaaa atggcttttt
    12961 ccttacgata cctttggcac aaaaaatgac tgtttcgttg aaagttcgga atttcaatag
    13021 ttctgtttta aaagtcaatg atttggatgg aaaccccatc gaaatctcag cagtagtagt
    13081 ctttaaagtc gttgatacag caaaggcatt attcgatgta gcgtattatc aagattttgt
    13141 agaaatccaa agtgagacag ccattcggca tatcgctagc caatacccgt atgatacatt
    13201 caatgagaat gatttgacgc ttcgaggaaa cacgacggca gtgtctgacg agttgcaaaa
    13261 agagctgcaa gagcgtttag cagtagcagg tgtcgaagta atcgaaacac gcttgaacca
    13321 tttagcctat gcaacagaaa tcgctagtgc catgctccaa cgtcaacaag caaaagccat
    13381 tttgtctgct cgacaaacca ttgttgaagg agctgtcaca atcactcaaa tggccttaga
    13441 gcaaatcgaa gatggacaag aaatcaattt caccgatgat cggaaagtcc aattgatcaa
    13501 taatttactt gtctcaatca ttacagacaa aggaacgcaa cctgttatca atacaggcga
    13561 catgaaagac cgtaagtgac atactttttg taagatagga agaaggagtt taggacggat
    13621 tattgtcttg aactcttttt ttagttgttt taaagaaaat gacaaaattg aaagaagaat
    13681 gatagttgat tcgaaggcag aattgttcgc ttttttctat aatcagtata taaagtaaga
    13741 gagaagggga aaaagtgaaa aaacttctga tcggtctact tgttttcatc gttgtggtac
    13801 ttgcaggggt gaaaatcgca gattacgtag ttatgggtgg agaagaatac tatgtacaaa
    13861 ttacgacaga tggtacaaaa acagtttcaa aatcagactc tggacaagaa acagtcaact
    13921 atagatatat cctgcctggc tatacgaaag agggtaagga aaaagaactg gacttcaagg
    13981 gacaattgac tcgaccgctt cgtaaaggag catatttaaa aatcacctgg aacaaaaata
    14041 aaggtgtcac ttcgtatgaa gaagtcgaaa aaaaagacgt gccgaaaaca gcactggaaa
    14101 aactaattaa agggtaggga aagaaatgaa caaaatagtc gaagtacaga atgtaacaaa
    14161 agtatacgga aaaaacaatg agaaaaagac gcaagcatta agcggcatca gcttcgatgt
    14221 agaaaaaggc gaatttattg ggatcatggg cgcttctggt tctggtaagt cgacactttt
    14281 gaatatttta tccacattag ataaaccaac agatgggcat atccgaatca atcaaaaaga
    14341 tgtgaccaca ttaaaaggaa atcaactagc agattttcgt gcgaatgaga ttggctttat
    14401 tttccaagat ttcaatttat tagaaagctt gacagcacaa gaaaatatcg ctgttcctct
    14461 ttctttacaa ggcgtcagac caaaagaaat caagcaacgt gtccaaaaaa ttgcagaacg
    14521 tttatccatc tctcatattt tggaaagcta tccttctgag atttccggtg gacaaaaaca
    14581 acgggtcgcc gccgcacgtg cattgatcac acaaccaacg attctattag gggatgagcc
    14641 tacaggtgcg ctggattcca aaagtgcccg ggatctttta gatacgatgg acgaattgaa
    14701 tacaaaagat catgtatcga ttcttcttgt gacgcatgat ccgttttctg caagttattg
    14761 ccaacgtatt ttattcatca aggatggcgg tatccatcaa gaagtgaaac gtggagatca
    14821 aagccgtgat tccttctatc gagaaatact atctattctt ggaaacttgg aacagtaggg
    14881 ggagattgac tatgctttgg aaattatcac ttactgggat caagagccgt ttaagagact
    14941 acttggtgtt attctcagga ttagttatgg catctgctat tttttacatg tttgaatcaa
    15001 tggcaagcaa cgaagctttt ttgaaaagta atacgatcgt tgcggctaca gttatcattt
    15061 tccgattcgg ttctgtttta ctagggatca tcacattcgt ttatatttta tatgcaaatt
    15121 cctttttgat gacgatgcgg caaaaagact atgcaatgtt tatgatgctg ggagcaaaag
    15181 gcagaaaaat cgcacagatg attttttctg aaacattctt agtagggatc gcagctactt
    15241 tagtgggttc agctgtcggt gtaggattga caagtatcgt ccaccgatta ttagtggatc
    15301 agttagatct caatatttcg cattttacac cttttagtat tcacgggttg ttgatcactg
    15361 ttttgttttt tgctgttttg tttttattag ctgctgttgt caatgctttt tcgattgtca
    15421 aaaaaccgat tttagcattg attcgtgcgg atcagacacc aacaagaatc aagcagcata
    15481 aattcttgtt tttccttgaa gtagtactgg gaattgcttt tctaggctgc ggttactata
    15541 tgatgaaaca cgtggggacc tatcaagtct ttggtatagg ggtagcctta gttacgatcg
    15601 tattaggaac ttatttcatt ttccattctg tgatcatttt ctttttatca ttactaaaga
    15661 aatcagaaca gatttcattg aaaaaattga acaatttcac attgtcacag ttaaactttc
    15721 gtattcgtga atatacacaa atgctctcaa tggtcgctat gctgtttgcc ttggcactgg
    15781 gcgctttgac ggtaggatta ggttttaaaa atgaaattgc agacttgaca gaaaacaatt
    15841 ctggatatga tctagtgatg aataatcctc gggcagaaga tcagcaaaaa atcaaagaac
    15901 tttcaccaac actttctgct tcttatactc aaaaagaaga tgcgggaacg atttactata
    15961 atgcaagtga atttgcggct caaccattga tcatgataaa acatgaagat ggaacaccgc
    16021 cgaagatcac gaaagaaaaa gttcctgcta aaaaaatgaa tgaactgact gtacaagagg
    16081 aacttcgaag ctatgaattg ccggaacagc aagaaaaaga aatcaaggta gtcagtcaat
    16141 cagaatttga tcaactgaac ttgccacaat ccactttaca gctagttcag gtaaaagact
    16201 tccaagcaaa cctgaaacca atcgaaacac ttgttgctca aaataaaatg aacaatccat
    16261 ctttgcaaaa agtagagtac agcaaccaga aatatgaaat gtatgaagtg tataatggtc
    16321 tattctctgg ttttgaattt atgggattct tcctaggttt agctttcttg accatgcttg
    16381 ctagctgttt gatgttcaag atcttgtcag gaagcaagag tgacattgct cgttatgaaa
    16441 tgcttgaaaa gataggaaca cgacgcgggt tgcttaaaca atcgatccgt agagaagtag
    16501 gcgtgttatt cttagcacca ggaatcttag gtgtagtcca tgtcttattc ggattacaaa
    16561 tgtttggtct attcatgcaa aatccataca aagatatttg ggttccgttt acgatattct
    16621 tcgtattgta tttcatctac tatgtactga cgacatggtt atatactgga atcgtattga
    16681 aaaagagatt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa gcaaaaatag
    16741 ctcctcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    16801 ttgttcggaa aaagaggttg tgacaatatt tttgtcacaa cctttttttc acggtctttt
    16861 attagaatat agtaaatttt ttctcgttac tcacggaata agctgttaag aaaacggttt
    16921 ccatgtatac tggaatcagt gcaaatgaaa gaaaagaggg tgcaaggaac atggaaatca
    16981 atgaacaaaa ttttggcgaa aactatcact tgattacgat cacgaatcaa aatgggacat
    17041 ctttgtctgt cagtgatctt ggggcacggg ttgttcattt tcaaacaata atcgataatg
    17101 aaaaacgaga gttgatctta ggttttgatg aagcaaaaga atatctagaa aaagaccctt
    17161 atatcggtgc ttcaatcgga cgtatggctg gacggattac gaatggcaca ttcaaattag
    17221 atgatgaaac gttcgaagta aaaacagacc cggacactgg tcattgttta catggtggtg
    17281 cacctagctt tgaagccaag cagtggcatt atacagtcat caatggtgaa aacgaagcat
    17341 cggtcatttt ctatcagact agcccagata tggaaaacgg atttcctgga actttagatg
    17401 tagaagtacg gtatacgctg acgaacgatg atacatggcg agtgacggtc caagggatca
    17461 gtgaccgcaa aacagtattc aatcctacaa atcatgtcta tttcaattta accggtgatc
    17521 cagcacagtc aatcgacgaa catatacttt ggttgaatag ccgattattt gctacgctca
    17581 ataaagatac aacgcctaca ggagaagtag tttcagtaag tggcacagca tttgacttcc
    17641 aacgtcctaa aaaattaggt gaggtctttg ccagtgattt tcgccaatca atgatagtgg
    17701 gcggcatcga tcatccattt ttgttgaaaa aacaatctgg tttactaaat gctgcggaat
    17761 tgacaagccc agatgaaaaa gtatcgatcc aagtaaaaac agatgcttca ggaatcgtga
    17821 tttttacagc aaattttgga gaagatggac cggaaatgcg cgggaataaa ttagtaaatc
    17881 atggcggtat cacatttgag actcaagaac tgccaggagc ggagcgactt gaaagttttg
    17941 gagatgtcac tctggaacct aaccaagtac gcgagtttgt aacggaatac aaaataaata
    18001 taaagaaata gaataaatta aaaagggagt gtgacagtgt cacatcccct ttttaattta
    18061 ttctatttct ttaaaggcag atcaagccag aatgatttgt ctaaacttaa caaggttagt
    18121 acaggaacag ttgcagcttt aactgtacga gtagttgttt ctggtatctg tcttgccgta
    18181 aaattgttcc acaaatccca gattgaagcg acacggaaga tggaagaagc gttgttgacg
    18241 cgttttatcg ttgaaaattc taatcctgtg attggcacgc catctgttgt ccatttgatt
    18301 ggcacatcga atcgcttaga catattgagg atttcagcgt ttgcttcttc agttgttgct
    18361 gcttcttttt tcggttcatc atattttgtc aggtcgtacg cttcgatgat cgcgttcaat
    18421 ttttgtgaat attggcgatc tgtagcataa cgtccttcca aatatttggt tgcttctttg
    18481 tagtcttttg tttccgactt ccaagttggt ttgtagaaat caggattgcc agtcagtcca
    18541 tttttgatca agtcggcata gtcttccaaa ctttccttgt aagaaggata tttacggaat
    18601 tgtgcgcgga tttggtagct ttgtccggaa ctatcttgtt caagtgtatt gaaggtcacg
    18661 ctgcttcctt tatatgatcc tttgatacca aaaaggttat gatttggttc gcttgataat
    18721 aagctgtttc cagatccact ttcaaggata gcttgagcca tcatgactga tgcgtagatt
    18781 ccttcttttt gcccgatttc ctgtgcatca tctgcaatct ttttcaagaa ctgatcagtt
    18841 gtttggtttt gactgaaatg gaacgagcca tctaatccat ctaaaataga tgagccgcct
    18901 gtcagcgaac ctgaagcagc aggtaaacct gctaagttta ctcggacagc aaaatcaggc
    18961 gtgaaatctg aaatagaagt tactcgaact ttatctcctg gttgaggcgc atggataaat
    19021 tgtccgttcc caatatagat acctacatgg tgagtaacac cggaagaagg tccccagaag
    19081 acgaggtcgc caggttgggc ctgacttact ggaatctgcg tacctgcata ttgctgttcg
    19141 cctgtccagc caccgatata atgaccggtt gctttcatat atacgtaata agtcaaacca
    19201 gaacagtcaa aagtatttgg accttttgct ccccatacat atggttttcc aagatgcttg
    19261 aatgcttctc gaacgattgc ttgttggaca ttcgttgtat ttgtaggcaa tacagcatca
    19321 attggtgatt ttacaacaaa atcagaagaa gcagaagatg gattctctat accgctttga
    19381 tttgctgtat ttggacgaga tgaagcattg ttcgttccgc cattcgatga accattgttt
    19441 ggatggtttg gttctctctg agtatttcca ttgttattcg atccagatgg gtttgtttga
    19501 ttcgaagaat tcccgctgtt cgaattattg ttattattgt ttgaattatt tgaaccatta
    19561 ttattgttgt tattacccac atctggtttg tttggcgttt ccggatctgg tgtactaggg
    19621 acttcttcac taggatcagt tggtttctct gttgaagtat ccggtccagc tttaaattct
    19681 gcagtaatag ataaattgtt cgtacctact gtaaaggtct ttgcatcata atttacttct
    19741 ttggcaccat taacagcgac tgaagcaatt tgttcacctt cagctggcgt aatagtgtaa
    19801 gttaccttcg tttccgctaa taaaccttct accgttccac tttccgtaat atccaaaggt
    19861 tgctgttcag gggaatccgc tgtcgaagca gtcagttgga tcttaccaat caaagaagga
    19921 gcaattgtaa gggaatatgt ctcggctggc ttttcatttt ctgatggatc agccggatca
    19981 atttcagttg gctcggtcga tcctgttgtt gagttagttg ttccagttgg gtcttctgta
    20041 aaagaatccg ttgtttcact agtagctgag ctggatgtag tcgtatctgt tgtgactgtt
    20101 tgatcagcta tttgattatc tacggcaaat acggtattgg tcgacaaaac agacggagca
    20161 atcagccaag tagcagctag caaacgtatc gtttttttat ttttcataat aaactagtcc
    20221 ttttcctttc attgattttc tgtcttattc agcattcatt agacattttt tggaacagat
    20281 aatcgtgtcg aaaagctttt tcttttcata aatctgtctg tgtattctaa ataaaacaat
    20341 ttgtaaataa gcaacgagca ttcattcgtt tttctttgac gttcatttta ttgcatagac
    20401 cacctttgtt tggggataaa caagtgggga taaaaatggt tatgcatatg taaattatac
    20461 caaagtttgg aaagtatcac aaaaatttat aaaaataatg atcctaaaaa gaaaaagact
    20521 gaaatatgtg ataaacatct catacttcag tctttttcat taactattca taagacatta
    20581 ggtcttcatc aaacccgcta acgagagtag tgatcattgc tacgactaga ctaacagcca
    20641 gtcctgctaa gtaccagaaa aaagtaccgg aaatgaatgc aggcaatgtg gtcagactac
    20701 caaatacaaa agcgatcgct ttcacttggg caaatcccat tacagctcca ccagcagctg
    20761 caccaatgca agcagcaaca aatggttttt tcaatgggat cgcaattccg taaacagttg
    20821 gttcggtcac tcccgcaagt aaaatcgaag caaaagcaga accggagatc gaacgggttt
    20881 ttgaacgttt acttcgcaga aatacaccta aagctgcacc agccattcca aaattggctg
    20941 ctcctgtcaa cggaacgatt cggtcgaacc cataagcaga gatattactg atcatgacag
    21001 ggtttacagc ccattggata ccaaatatta ccaaaatatt ccaaccacca gcgatgattg
    21061 cgccactgat cggtccgtta atatccatca tccaagtaat tgcggcagct aaaccttcgc
    21121 caaggtaaac acccgcaggc ccgaatacca ttaacgtcaa aggaaccgtg ataactaatg
    21181 aaagtaaagg tacaaatact aattgcatat tttcgcgaat atattttttg aggaattttt
    21241 caacaaaaga ataaaagaaa atacctaaaa tcgccggcat gacagtagac gtatactgca
    21301 tcagtactac aggaatcccc agaaaatcag tagctgcttt gccactgtct gaaagtaaag
    21361 aggtcagatt cggttcaatc agtgctgcag caatgacagc cgcaatatat ccattcactt
    21421 taaacgtttt ggcagcagaa aaagcaagaa agattggcag aaaataaaag acggcattcg
    21481 acgcagcaga caaaatatga taagttccgc ttgtttcact aagccagcca atcgtagtcg
    21541 ctaaaacaac cagacctttt aatataccag aaccggcaaa cagcggaatg atcggcgtaa
    21601 agatttccga tatcaaacca aatagttttt cgatcggatt tagcttttct ttcggagctg
    21661 aatgatcgat ttgacgcgtc aattccttgt aagcaggagc caatccctga tccatgatta
    21721 tttctgcata tctatcgagt aaaatgaaat acttaatgga agggatttgc tgttttaatt
    21781 tttctgcatt ggctactggc tgttttttca atttgatacg aagccgagtc gcacatggaa
    21841 ggacagaatc aatattgtct tttcctccca actgttcaat cagcatatga atctgctcgg
    21901 acagtaccat ctgttcagga ttcattgtcg tttccattag aagaccactc cactcactaa
    21961 tataatattg gcgtaaggtg tcatttcgcc tgtacgaata aatgcatgac agttattcaa
    22021 ctcttttttc atttcttcat gtgggataaa gctaatcggt gtatctggta acaataattt
    22081 gattttttcc aatatttccg ggttcattgt ctttatttct tccgccaatt caatcgattg
    22141 tacctcaagt tcttctaaaa cgttttctaa aacagataaa aaacttggaa gaccgtttga
    22201 gacagccaaa tctatttttt cagtaccaaa ggggacaggc atgcctgcat ccccgatact
    22261 taatttatca aagtgcccca tttgtgcgat tactcgtgaa atatctgaat tgattacttt
    22321 tccttttttc atgtttgttt cttcctctca ttgttaattt tagactgctg attgttctaa
    22381 agcttcgcgg taagggatag aaggttgcgc accataagac tgcacagcaa cagaagaggc
    22441 tagatttcca taaaggatcg cttctttcaa gttactaagg tctggctgaa gtgtgctgct
    22501 taatgcgcca ataaatgtat cacctgcggc tgttgtgtca acggcatcca ctttaaaagc
    22561 agggacgata ccgtgttctt tttctgtatg atagaaagcg ccggcactgc ctagtgtaat
    22621 gattactgtt ccaataccta attcatggag tttttcggct gctgcgacca aactgttatg
    22681 atctgtcact ctgattcctg taatgatttc tgtttctgtt tcatttggta taatgatatc
    22741 tgtcttttca agtagttcag taggaatcgt ttcacgagct ggtgcaggat tcaggatcgt
    22801 tgtttttcct gcgtcttttg caatagaaaa agctaggatc gtcgcatcta agctactttc
    22861 aaactgagca ataataaagt cactgtttgt aatcagttgc ttgtttttta ggacttcttg
    22921 ttcatggaaa gcattatttg cccctgcatg gatcaagata ctattttctc ctgctgcgtc
    22981 taccataatc attgcttgtc cggttgtggc gccttggatt tcagctatcc cagatgtatc
    23041 gatgttttct tttgtcagta gatctaataa ctgttgtcct tcgctgtcag ccccaacgcc
    23101 tccaataaaa gatgtccgtg cgcctgaacg tttggctgcc actgcttggt tggcaccttt
    23161 acctccgcca gcgtgaaaaa tctcatgcgc atgcatcgtt tcgcctggct tgggcatgtt
    23221 ggttaaacga agggtagtgt ccatattaat acttccaatt actgtaaccg tgttcatttt
    23281 acaaacctcc aactatctca tttattttga tgggaaaatt attttttaaa acgttttagt
    23341 aaaacgtttt aatagttcga taaaaatata gcacaccttg aaagctattt caagggtgca
    23401 gttgaaaatc ttttttctaa tcgtacaggt aatctttttt cttcccattc tttttctggg
    23461 aattggatcc gatctaacaa taacttggca gatgtttgtc ccaattcgaa gattggttgt
    23521 gcgatcgttg tcagtttcgg cttgatatac tcgcacatat ctatattatc atagccaata
    23581 atgctgtagt cttcagggat gctttttcca gcttcctcta atccgcgata taatccaaaa
    23641 gctaattcat catttaaagc aaacacacca gttgcagcag aatcaagaag ttctgctgtg
    23701 atctggtagc caccttgttt tgagaactgt gtaggtaaga ggatcagttg gtcgtgaggg
    23761 atttggtaaa catcaagagc agatttaaac ccctcaatcc gagcgtggac attttccggt
    23821 ggattttcag gatagacaag ggcgatcgtt tgatgtccta gactaagcaa gtgcatgccc
    23881 gctaggtaac caccgcgaaa atcgtctgtt cgtacggcat cactaaatcc ttcagatttt
    23941 ttctgatcca aaacaatgaa gggccggcct tgttttttca aattttcgtt gattgcatct
    24001 gtagagacag cagaagtcgc gataatgaat ccatccacac ctcgacgtgt gagctcggct
    24061 agatattcga tttctttttg atgatcagaa tcagcattac ataatatcgt gacgaaattc
    24121 tgcttataca agatatcctc aattcctcgc atcagtgtac tgaagaatgg attcgtgata
    24181 tcaggaacga gtacaccaat tgttttcgtt tccttggtaa tcatttgtct agcaaaatag
    24241 tcaggctgat agcctaattc ttctttggca gctaaaactt tctgaacagt tttcggactg
    24301 aatttctccg tatttccatt taatatcaag gagacagttg tgattgaaac gccggaaagt
    24361 ttagcgactt ctttgattgt gatctttttt ttcaccatgt tcatactcct atctaaatcc
    24421 tgtggttatt ttcccatgaa atcaaaaaga agtaaatgaa aatcacgtgt gccagtactt
    24481 atttgctttg ttggatagct tcgattattt gtttcgttga gcgtactcgt gcagttttcg
    24541 gaaatatctt ttttatgaac aattgatggg attctttgtc acgatcactg caagcatctt
    24601 cagcaagcac gatatggtac ccgtgttgaa aggcatctaa tgcagtagca tatacaccgt
    24661 ttgttgtcgc tacaccgctt aaaatgatag tttcgattcc acgccggcga agttgaagat
    24721 caagagaagt accaaaaaaa gcacttggat tgtattttgt gatagtcaac atattatctg
    24781 tatctttcaa agaatccttc aaaagtaaat cagtgaattc tggaggtaca gaagcagtca
    24841 ttccacccat atcagtttgt tgactcaaat aagggaaagt ggagatgtct acgttcacta
    24901 aaactttcaa ggcagcggta cgtttcaatg ttcttactaa caaatcattg tttgtcagaa
    24961 tagatgctgc agtgtgtgga gagagtgtac cgttatttac gatctctttt tgcatgtcga
    25021 tcgcgacaaa agcagttttt gataaatcaa aaatcatatt ttcctttaaa tcattcatga
    25081 tgttccttct ttcaaataac aatgtttttt atgtaagtaa atcataaatc gtttatttgt
    25141 caactaaatt aaaggattcc tttctttagt ctagagaaat tcagtggtaa aataaataag
    25201 tgtgagaaaa cgcattcgat gcatagatat agcgagaaat atcgtgaaaa tggaggaatc
    25261 agagtgaagt atgtcgaagt aaaaaatgaa tacaaacgat acaaaatggg agaaacgacc
    25321 attacagcaa atgacgatat ttctttttca attgaaaaag gcgaattagt gattatactt
    25381 ggtccaagtg gagcaggaaa gtcaacgatt cttaatattt taggtgggat ggatacacct
    25441 gatgaaggtc agatcattat tgatgacaca gatattgcgc aattttcaga taaacagctt
    25501 actgcttacc gacgaacaga tgtagggttc gttttccaat tctacaatct cgttcctaat
    25561 ctaacagcaa aagaaaatgt ggaattggca acggaagttt ctcctgatgc gcttgatcct
    25621 gtagaggtat tgaggcaagt gggcctagct catcgattga ataactttcc gtcccaatta
    25681 tcaggaggcg aacagcagag ggtttcaatt gctcgtgcac tagctaaaaa tcccaaactt
    25741 cttttatgtg atgaaccgac aggcgcgctg gattttgaaa cgggcaagca agtattgaaa
    25801 ttattgcaaa acgctagcag acaacacggc aataccgttt tgatcattac acataattct
    25861 gctttagcgc ccatcgctga tagagtcatt cacattaatg atgctaaagt aaggtctgtt
    25921 gaattaaatg atcatccttc atccattgat gagattgtat ggtaggggga ttttatgaaa
    25981 acaagaacat atcttaaagc aggttttcgc gaaattcggc aatctaaagg acgattcatt
    26041 gcaatcatcc ttattgtcat gctaggaaca cttttatttg taggtgtcaa aactgctgga
    26101 cctgtcatgc aaaaaacgat ggatcactat gttggtacag caggactttc tgatttgcaa
    26161 atcgtttcta ctggtggctt gacacaaaaa gatattgctc aagcagaaaa gatcccagat
    26221 gcaaaagtag aaacaggaaa acagatctat tattccaata ctggcaaaaa cgaagtgatt
    26281 caaatatttt cttataacaa aaataacaag cagaacaagc tacaattaac tgatggaaaa
    26341 ctcccggaaa aaccaaacca gcttgtattg gatgaaaaag cggaagatga agggtataaa
    26401 atcggtgata tttatcagat tgattcagat gaattgaaag aaaaagagta taccatcacg
    26461 ggctttgtcc gttctccatt gttcatcaac aatttggaga gaggatacgc gaacgtcgga
    26521 aatggtagcg tcgattattt tgtctattta cctgaatccg tttttaaaac agatatttat
    26581 tctgtcttat atcttgattt tacaaacgta aagaatttga atacgtacag caaagcttac
    26641 aaagataaaa tggagcaaaa tcaagaaaag gcagaaaagt atttacaaga tcgacccgaa
    26701 gaacgcttag aagagctgaa aaaatcggcc aacgaagaat tagaaccggc acagcaaaaa
    26761 atagcggatg gcaaagcaca aacaacgcaa gcaagaacac ggttagaaga tgctaaaaaa
    26821 cagttagcgc aacagtcagc aactatccag cagcttcctg aagcgcaacg aacaatcgct
    26881 gttcaaacat tatctcaaca agaagctcaa cttgctgaac aagaaaggca attagttgag
    26941 aaagaacgtg aactggcctc tgcagaggaa gaattgaatc gaaatgcaga aaaaattgaa
    27001 aatttaacta aaccatcata cctatacaat gaacgttcag aaaatgtcgg ttttcaagaa
    27061 tttggtgatc tgtctgatcg tatcgctgcg attgccaatg tttttcctgt tttctttttc
    27121 tttattgccg cattgatcac ctttacgaca atgacacgta tggtagaaga aaaccgcagg
    27181 gaaatcggga cattaaaggc gttaggttat acgaaagttg aaatcgcaaa aaaatatgca
    27241 atctatgcaa gtctagcctc agggataggt attgttttag gaacgatatt aggaacgaat
    27301 cttttgccaa ggatcatttt tgagctgtct aacgagcggt atgatattgg gagtgcgctt
    27361 attttttatg actggccgcc gattttacaa gcagctgccg cattcttcat tgccgcattt
    27421 ggcgctgcaa tgatcgtttt attcaaagat ttaagagaac ggcctgctgc attgcttcaa
    27481 ccgaaagcac cgaagccagg gaaacgcatt tttcttgaat acatcactcc gctgtggtca
    27541 cgccttagct ttaatcaaaa aatcagttac cgaaatctct tccgatataa gtcaagaatg
    27601 cttatggcga ttatcggaat tgctggatgt gccgggctga tggttgcagg cgtgggattg
    27661 aaagattctc taagttctgt ttcagccaaa caatttggac cgatcattga ctatcaagca
    27721 atcgttacat tggattcatc cacggaagat agtcgtcaaa aagcagcgga tatgctgcag
    27781 aagcaagaaa aagtaaatga gatcctagct attcatactc aaaccgtaga attgagaaaa
    27841 aaaggacatg cttcgcaaag tctgacagtg atcgtaccaa gtaaaacagc tgatttggat
    27901 cgttttatcc atttaactga tcttgaagag aacccacgct ccttgcctaa aacaggaatc
    27961 gctattacgc aaaaagtagc agaactattt gacttatcta caggagatca tatttcgctt
    28021 tatgatgaag atcaaaaaga atggaaagtc gaagtaaaag aaatcgtgaa aaactatcta
    28081 ggtagcttta tttatatgtc ccctgaatat tatgcttcag ttactgatca atcgatgatg
    28141 gataatgcat ttttgctgcg tacagataag atgacaacaa aagaagaaga aatgctttcc
    28201 gagaaactgc ttgccacaga cgctgtgaca aatacgtctt tcatgtccaa acaaatcgaa
    28261 acgcaagaag aatcaatggc gaacttagac tcggttgtct taatctttgt cgtattatca
    28321 ggactgctgg cttttatcgt cttgtataat ctaactaata tcaatatttc cgagcgtgta
    28381 cgcgaattat ctacaataaa agtccttgga ttttttgata aagaagtcac gatgtacatt
    28441 gttcgagaaa atatcatctt tactctttta ggaatcatcg gaggatttgg tgtaggatat
    28501 atattgactg acttcatctt gcaacaagcg tctatggaga atgtcatctt tccattagtg
    28561 atcacatggt gggcttatgt cttatcagca ggattaacta tcgtatttac ggttattgtg
    28621 atgattgtta cccatttcaa attaaagcat atcgatatga ttgatgcgtt gaaatcgaat
    28681 gaataaaaac agaggttgtg aaatcagcgg tttgacctga gtattagaga aacaaacggc
    28741 aaaatagttt ttcatatttt gccgtttttt gagctaatac cgaaggacag ctgattgaac
    28801 accatgaatc agaggttgta aaaaagccgt cctgcatcga gcaaaaagaa tactcaaata
    28861 aaattagctc ctcatgtttt acatttgaga agactgattg ccgtagataa aagcttttga
    28921 acaccattta tagaagaaac aagaatattt tgctatttta aacaagagga tagacaaata
    28981 catgtctgat ctcttgtttt ttattgggca acagacctct tagaatgtat aaagataaat
    29041 tttacaaacg ctttcggttc agttataata ataaatgata acttgtatat ataagttgtg
    29101 gtaggtaata aatcagttga atggaggtaa atatccatga catttaaaga caaagtcatt
    29161 taccaaatct atcccaaatc ttacaaagac agtaatggtg atggaattgg agatttaaaa
    29221 ggaatcaaag aaaaactccc gtatctgaat gatctaggca tcgacatgat ttggctaaac
    29281 cctatttatc caagccctca aaaagacaac ggttatgata tctctgatta cacagccatc
    29341 gatcctatct ttggtacgat ggaggaattc gaacagctaa tagccgaagc aaagaaatac
    29401 cggatagaaa tcatgctcga tatggtgctg aatcacgttt cgacagaaca tgaatggttc
    29461 aaaaaagcac tagcagggga ccagcattat caggacttct tcattttaag agaagagcca
    29521 acggattggg tatcaaaatt tggtggaagt gcttggtcgc catttggaga tacggggaaa
    29581 tattatttgc acttatatga tcggacacaa gctgacttga actggcggaa ccaagcagta
    29641 agagaggaac tattcaaagt tgttcgtttt tggatggaaa aaggggtaaa aggattccgt
    29701 ttcgatgtta tcaatgttat cggtaaagac gaacaattga aaaataataa agaaaatgat
    29761 ggcaaacctg aatatacgga caaaccaatc acccatacgt atctaaaaga attgaaccaa
    29821 gcaacgtttg ggacggattc cactatcatc acagtcggtg aaatgagctc tacgacgatc
    29881 gaaaattgta tcttgtatac agaacctagt agagaagaat tatcaatggt ctttaatttc
    29941 catcatttga aagtcgatta tgaaaatggg aataaatggt ctactcctcc atttgatttt
    30001 gcagaattaa agcgactatt tcatacatgg ggagaaaaga tgagtgaggg taacggctgg
    30061 aatgctctat tttttaataa tcatgatcag ccacgtgcgc tcaatcgatt tgtagctatc
    30121 gatcagtatc gaaaacaagg agcagagatg ctagcaacca tgatccattt gaaccgtggg
    30181 acgccctata tttatatggg agaagaaatc ggcatgatcg acccagacta ttcatcgatt
    30241 tccgactata ttgacgtaga aagtttgaat gcttataagt tactccttga acaaggattc
    30301 acagaaaaag aagcgtttcg tcggatcaaa gcaaaatctc gcgataactc tcgaacaccc
    30361 atgcaatggt cagacacaga acaagcagga tttactacag ggaaaccttg gttaaaagtt
    30421 ggaggcaagc tagaagagat taatgtagaa aaagaactat cttctgaaga ttctattttg
    30481 tcctattaca agaaattgat tcggctgaga aaaacatatc caatcgttgc acaaggagat
    30541 tatcatgctt atgaagcaaa tcatccggaa gtttatggct ttcttcgcca atttgaagga
    30601 cagcagctgc ttgtattaac aaatttctat gataaagata caaggatcgc catcccagaa
    30661 ggattcacag aagccaatat tcttatcgat aattattccg atactgttct tcatcaaagt
    30721 ctggagctaa aaccatacca ggcaattgct ttgctgaaaa attaaaacaa aaacacaaaa
    30781 cgtcgttcct acgagctatt ctcgtaagat cgacgttttg tgttttattt aaaataatct
    30841 tcttcagaaa atgaagagtt ttcatactct cctttatcgc cataaaattt attgtagcgt
    30901 tgtttgaatt tacggaaaat aaaagtaacg agtaatttga ctaacgtata gataggaata
    30961 ccaaaaataa cgcccacaat tcccattaga tcacccatga caagtaaaac gattaagatc
    31021 gtaatcggat ggatctgtaa acgatcaccc attactcgag gaatcaccaa gtcaccgtgg
    31081 agaagttgta cggcaaacca gacaatgaca aatttgacag ccataaaagt agagtcttgg
    31141 aatgcaatga tcaaacctgg aaagaaggcg ataaacggcc caatatatgg aatgatacat
    31201 aacaacccag cagaaatagc taaaacacta gcaaattcta atccgatcag taagaaacaa
    31261 acccagtaga ctgctccaag gataaatgaa gcaatgattt gcccctttag aaatgaaccc
    31321 aattgttgat tagcaatctt tgtcaaattt ttaaaatctg tacgaaatgc tggtgggaca
    31381 atcgctaaaa ctgactgata aaatttttga ggatctctca aaaggaaaaa agcgacaatt
    31441 ggaccagtaa ataaagtaat aaaaatagct gtaacagttg aaaaaatgtt gctgatccgt
    31501 tgtgcgccac tttcccaata atttccaata aatccagcta tatcagacgt cacgtcgtca
    31561 atagaagcga aaaattgatt aaatgaatcg gcaaaaggtg ttttctccaa aaattgtcgg
    31621 agactctctt gaaaatcttg aaacaaatct ggcaaactac tgatcaatgt ctttgcctgt
    31681 tcttcaagaa aaggaataag ccatatgctt ccaagcccca ataaaaataa aataatcaca
    31741 taaacgataa tgactgacaa gttcctcgaa aggtgcttgc tcaaacgttt gatgactggt
    31801 tccaaaagat aatacaagat cagtgcaaac aataatgggg gcaagatagt agcgataatg
    31861 attccgacag gcttgaatat aaacgagatc tgatggaaaa aataaatgat cagcgcaagt
    31921 aagataacta ttcctaaaac atagtaagag gtttttcctc ctaaaaagcg gatcaaacga
    31981 ttcgttgtat ctgtttcttt tttcactctt tttcctcctt tatctataaa ttcattatag
    32041 acaaaagcgg gtataaaagg aaaatgatag aggttgattg caaaaatatc gtcaatcatt
    32101 catataaact ttctcatcaa ttaaaataag aaaacgcttg acagttcttt taaccatatg
    32161 ataaattaaa tcctgttgct aaaacgtaac tattacggtt tgcgaaaagc gaatcggaac
    32221 attcaaatga aagaagatga gaagaggagt gtcataaatg aaacgattga taggtatatt
    32281 ggccatgctg gttttagcag gtatgttaac tgcttgcggg gcaagtggga aagccgagga
    32341 cagtaaagaa aaattgagcg tgatgacgac cttttatccc atgtatgatt ttacaaaagc
    32401 aatcgtcggg gatgaaggag aagtagagtt attgattcca gcagggactg attcccacga
    32461 ttatgaacct tctgctaaag acatggcaaa gatccaagat acagatatct ttgtttataa
    32521 tgatgaaaac atggaaacat gggtccccgc aatccaaaaa acattacaag aaggcaatgt
    32581 ccatacgata aaagcgacag aaggtatgct tttacttccg ggaagtgaag aaggacatga
    32641 tcatgaccat gaacacgggg aagaaggcca tacacatgag ctagacccac atgtatggct
    32701 agctccaagt ttagcaatca agcaggtagc aaacatacgt gatcagctga ttgaagctta
    32761 cccagaaaaa caggaagtat ggacaaaaaa tgcagcagcc tataccgaga aacttcaagc
    32821 actccatcag ctttatcaag aaacctttaa gcaagcaaaa caaagatctt ttgtcacgca
    32881 acatgctgca ttcaactatc tagcgttaga atatggattg aatcaagtat cgattgctgg
    32941 tctttcttct agtgaagaac cgtctgcggc gagaattgct gaactgaaac actttgttaa
    33001 agaacatgga atcaactata tttattttga agaaaacgcc aaagatagta ttgccagaac
    33061 gttagcaaac gaagcaggtg tatctttaga agtattgaat cctttggaag gattgacgaa
    33121 tgaacaaata gaaaatggag aaaactatct ttctatcatg gaagcaaacc tcgaagcgtt
    33181 gaaaaaaacg acagagacag aaaacccgct agaagatact ttgaccccca aaaaagaaaa
    33241 gagcgtctac aacggttatt ttgaagacga ggatgtacaa gatcgctctc tttcagattg
    33301 ggcaggaact tggcaaacag tagatacgta tgtagaagat gggacttttg atcctgtttt
    33361 tgaatataaa gaaaaattga atcaggataa gacagcacaa gaatataaag aatattatac
    33421 gaagggctat caaacagata ttgcttcaat caagatcagt gagaaagaga tggcatttac
    33481 gtttaagaat ggaacaacga aacgttcaaa ttatcgttat gtagggaaag aaatcttgac
    33541 ctacgaggca ggaaaccgtg gcgtaaggta tctattcgaa gcagaagata aggaaagtgg
    33601 cgcttttaga tatattcaat tcagtgatca cacgattgca ccggctgact ccgaacattt
    33661 tcatttatat gcaggaaatg aaagtcaaga agtattgctg aaagaaatgg agaattggcc
    33721 aacattttat ccagatacaa tggatggacg tgaaattgca caggaaatgc ttttgcactg
    33781 ataggcaaaa aagaaccgaa gggtttggat cggctggtca tttagtcggt ccaaactatt
    33841 cggttctttt tatgaaatca atttctttaa tccacggata gaggctggga tggtctcgcc
    33901 gtttgccaac gtgacttctc tggttttttt attaatcgac cgcacatttt gtgtattgat
    33961 aacataggat ttatgacaac ggataaaatt ccgatgcatt ttctcgattt ctttgatctt
    34021 ctcatagaat tgtaattggg catgagtcaa atggacttcc agtttatgtg gcgctcctag
    34081 cgaagtagaa aaatattgga tgtctttgat cggtaaaaat ttgatctcat cattaaactc
    34141 tattttgaag atatcttttt ggatttggga catttgaaaa tcttcgaaaa ttttgctcag
    34201 gatatgctcg acattttctt ttaaatcata aagatcttct ttgacgatat aatcagtcgg
    34261 ttcgatgttg ctttttaaga ttttcatcga catttccgta tgggaagtca catagattat
    34321 ttttcctaaa ggatctaatt cacggatcaa tttaccgatc gctacaccat ccatttcact
    34381 gtcttctagt tcgatatcta aaaagtaaat accaaaagaa gaagttctga tcttggctgc
    34441 attgagaagt tcttccggat cagaggtaga aatatggaca taactgtcta agttttcaat
    34501 catgattcta tttttgatca ccgttgataa aacttctaat tgttttggat cgtcttcaca
    34561 aatataaatg ggaatcatat cattactcct ttattttatt tgtatataaa tcgtttgaga
    34621 aaaacgctgg ttttcaattg atgtttcaag gaaaagataa ggattggtct ttgtcaattc
    34681 atccaagata aacaagccaa ggccttcgtt ttttggattt gtttttgttg agaacccttt
    34741 ttgtttcaac tggtttaacg gtaatgtatt tgttgttgta ttgatcacac gaatcatcac
    34801 ggaatgattc ttcttgagta tggtcaattc gatttttttc ttctttgcag cactagctcc
    34861 ttcaatcgca ttgtccaaga taataccaag catacgtaca aggtttaccg tatgtttcgt
    34921 atccagttcg attggctcag gaaaatgaag ctggacgatc aacccttttt cctgtgccat
    34981 catgagtttt aatgacagta aactacggat ctcaggaact ttcatattat ccaacatact
    35041 tagattggcc ggaaaaaggt tcatcatctg gcgtgtaggt aatatcgttt gatcataata
    35101 agaccgtaat ccttctaagt cgccttctga aatatagctg tgaagagaaa aaagcagatt
    35161 ttggtaatca tgtttgaatt ctctcaagtc ttgatagttt ttttctagat ctttgatata
    35221 atcctgttgc atcctgactt gttgctctaa taactgatca gctaatttct tattagagat
    35281 tttccaataa taaaccaaga tgatcaggcc aacacacaga tatagaatga aaaaactcgt
    35341 attcaaagct aagacatcag gtgtttcacc agaaaaacgg gtataaaaaa taatgatata
    35401 gtatgtaaat aatatcaatg tcccgatcgt accgatcata cggcggtcca cagtgtgaaa
    35461 ccaagtctct aacgattttt ttaaacaaaa agctaataaa gcagataaaa aagcggataa
    35521 gacaatgtga aaatactgca atgaatctcc tggttcaata accgaagatt tcaaaacaaa
    35581 aaaatcgccg atgcttgtta agtgatctcc taaaagcgac gtcaataacc caaaaggaag
    35641 cgcgtaaacc aattgttgac gcgaagtcga aaagaagaaa aaagtaagca tcagcattcc
    35701 tatagcaatt agagcagtaa aaatccctaa aatcgaatag acccatccaa tcaaaataca
    35761 agaaatcaga atgactcccg caaacagata tttgtatcgg atgtgatggt caatcaataa
    35821 gatacaaatt gtgtaaatca aatattgcaa cgctatggac cataaaaaca taaagtacag
    35881 ctcccattga tttttaccaa attatagcac aattggcgta ttattttttt aatttttcag
    35941 ggattttgaa ttcagaactc ataccaaagc agcagccaga tacaaaaaag tcagataagt
    36001 tagttaattg tttaatgatt gtttttttca tgaaagattc ctccaaaatt catcaagtag
    36061 tttgtaatag gaagcaacgt agctatttct aaaacaatcc caagtagcaa ataggtagaa
    36121 aagtaagaag ctgagaaaaa taacgtaatg agagaaaaaa ttagaaacat gctgatcgcc
    36181 ttctttaata atgggggacg tttctcgggt tcaatgggat tgattgctgt acctcttgat
    36241 ccatagcgaa gcagtaacaa aaagcagctg attaacaaaa agaccatcat tgggaaggag
    36301 atagtcaatt gcagatgttt catcaccaag ggaacgcccc ataaataaag tagtgtccac
    36361 agcagacaaa cgaattcaga gtcggaatgc aatccataag catatctgcg gatgcagata
    36421 taagaaagaa aggtgattcc tgtttccgcc catgagcctg tcaccagaga aaagactaga
    36481 acgaccgcta gttttccaag attattcaat aaaacttcta agacaaattt tacttggaca
    36541 tacaccatat cttcttccga tttgtctccg ctgaataagg cttctaataa tttgttcaca
    36601 actttatctt tcatctcata cgtacctcca ccacaaattt tatgctaaaa aaaataaaaa
    36661 acgtcttttg tttcataaaa agtggttttg acatcaaaac cgtcatgatc tcctaaaaaa
    36721 atcttcgttt tccaagaacc ttaccaaaaa aagtgacagt tttgatacga aaagtacttt
    36781 ttatgacaag tttgtgcttt ttcgagtgat ttatgttaaa aaattactga ccttataaaa
    36841 ggtgatggag ggattcttat ggaaaatgaa caattgtttg aagtcggcga aacatatgca
    36901 tttaaatctg atttatttga atcaccaata aaaggaaaaa tagaaaaaat ctatgaaaat
    36961 agtgtgatga tacgtgtcat gaaatgcgca gtagaagaca atgataccgc tcataatctg
    37021 cactggcagt tagttgtacg caaatcaagt acaatagaag aataaaaaca gataaaatgt
    37081 tgagagcata aagaggttgt gagtctcccg tttagctctg agttacaagg aataatgtta
    37141 aaaaacagct tttcatgttt tatgaatatt gccttgtgac cgaggtgttg gcaggagaat
    37201 actgtttatt tgaaaaaagg gctgcgacaa gacttttgtc acagccttta ttttcatgaa
    37261 taggagttac ttttggctac ttttagagaa gtagctttta aggagcagat aaagtcaagg
    37321 cttttatttc tataaatgaa gtagtaaaat gaagaacaga ttttattaca ggaaggatgc
    37381 cgataattgt gatcattgtt gcaggaacga tcggtgcagg gaaaagcaca ctaactgaaa
    37441 tgcttgccca agatttagaa acaaaacctt tttatgagaa cgtggaagat aatgaagtat
    37501 tgccgctatt ttattctaat ccagaaaagt atactttttt attacagatt ttctttttga
    37561 acaaacgctt tttggcaatc aaagatgctt tcagccatga tgacaacgta ctagaccgct
    37621 ccatctacga agatagtatg ctgtttcatt tgaatgcaga tttagggcgt gtttctgaag
    37681 tagaagtaaa gcagtatgaa ggtcttttag aaacgatgct gaaggagtta gaagaaattt
    37741 cgccacaaaa gaaaccagat ctactggttt atattcgtgt atcctttgaa actatgttag
    37801 cgagaatcaa aaaaagaggc cgggaatatg aacagctaga acaagatcct gaactctatt
    37861 cctactataa agaactcaat cgacgatacg aagagtggta tgaacagttt gatatatgtc
    37921 ccaaaatagt gatcgatggg gacaaatatg atttcgtagc cgatccggca tgtggagaac
    37981 aaatcgtaca agaaatcaag atgcgggcaa agaaaatgac agaagaggca gatgcccagt
    38041 cgatccgcta cactacaaat aacccgaaag caaagggaat ctttacaact aaataatata
    38101 aaaactaagc aaattgctca ctcgcagata tttctctgtg agcagcatct tgcttagttt
    38161 ttttgattca ttgagatcaa atagtgaacc gattcgtatg ataaaattgc cataaatgaa
    38221 atgtctgagt gagggccatg atcaaaaata aaatggaaac gatcaaaatc gaatgggcgc
    38281 caaacagatg atgacagaaa acaaggacaa tagctcctgc gataaaggca agaacgacac
    38341 ttagatagtg gaaaaatcga tcaaaatctg ctttttcttt agaaatacaa taatcatata
    38401 agttcgttgc tacccctttt aaatttccag ttgtaaataa attagtgtag gcacgcccgt
    38461 tgattttatc aaaagctacc cactggatcg atgcagtaaa agcaatcaaa atcgttacta
    38521 atgcgggatg ctcatggacg ggtgtcaaac taacaaagaa aaaaatcact gcttcataat
    38581 atagaacaaa caagcgccag aaatgttttt ctttttttct aaaataatca attagatact
    38641 ttgttagaag aatccctaag aaaaagaaaa gggtagacaa tactttttta ccaacactta
    38701 gccattctcc gtcaaatgct tggatgatcg atagaatgat attgccagtt tgagcagagg
    38761 caaaagcacc atattggata taagtataac tgtccatggc tcctccgata aatgtcagca
    38821 aaagtcctat tgtacgcccc tcgtgaaagg aagtctgcat ttttttcatc accttttatg
    38881 aatatttttg tcttccttat cttagcataa acgattgaaa aaaaggaaaa attttcagaa
    38941 aactaaaatc atatcgcttc ccattttcat ttttagaaag gtctgttagt ataaagaaaa
    39001 aatagacaac gaaactttaa ataaccaact tgaaataaac aaattcaaag aagaaagatg
    39061 ggaaggaaat caatcagttg aatgaaaaag aaattctccg attacaaaaa gaattgaaac
    39121 gctgggagaa caagtataaa aagcttcaac aagtctttcg gctacaagaa gaaatcattg
    39181 ctacctatga agcggcttat ggcgaagcac ccggacttat tgaggaagaa gtacaagtaa
    39241 aagaaagtga aggaaacagc tctttcttta aaatgatgga gaaacgttcc tataatcgct
    39301 tcaatcaaga acaaaaagca gctatcacat atgatatgaa gaaacatctt cgaatcatag
    39361 caggagctgg gagcggcaaa acgcaaacaa tctgtgcaaa agctgtttat ctgatgacgc
    39421 aaaaacaagt agacgaagaa cgcatactaa tgatcacttt tacaaggaac gctgcaaatg
    39481 aactaaaaaa acgagtagat aatttcagcc agagaaaaac cgctgtccat atcggaacat
    39541 tccatagtat cttttttagg atatacaatg aaatttgtcg aaaatttcct gaagtagcaa
    39601 tgcaaggaat acaaggagac ttttcaaagg atactgcaca aaaagtgaat gctgttttgc
    39661 aacagctgat acgtaaatat aatctttata tatttgatca atatggagaa aaaacgattg
    39721 cttctcggtt agactattgg cagaatatga acctttcagt agaagaaatg gttcagttag
    39781 ttaaagaaaa atatgattcc attgataaga atgcacgaca gccgatatca gaacgactgt
    39841 atggattgct cacggaactc caagaacaaa aaagaagcca gcaattgcta gagttcaatg
    39901 atgtactcca aaatctgaaa agcgctttgg agaatgagga gatccagcat tatatcggcc
    39961 aaaaatatga ttatctattc attgatgaat ttcaagatac taatccactt caatgggaaa
    40021 tcgtgaaacg gatgacaaag gaaaacagga tcaagttgat tgttgttgga gatgatgatc
    40081 agagtatcta tggattcaga ggatcagagc cagcatacat caagaacttt gaaaaagaat
    40141 atcctaccaa aactcttttc ttattaacta attatcgttc tcgggcagct attgtccaag
    40201 gagcaaatag attgatcagc tataataaaa atgatcggat accaaaggcg atgattccag
    40261 cacaaaaaga agcaggtgtt atggaagcct atttgttttc tgatactaaa gcagaaagtc
    40321 agtggctaat caaacaaatt cagacattta ttcaaaaaaa tgggaaatat aaggaatcaa
    40381 tcatattata ccgatcagct tcacaaacgc agcagcttgt ccaatctctg ctgaaaacga
    40441 atattccttt tgtactggaa gcagatagtc catatgaagg tatctttggt atcaagtctt
    40501 tccaacattt ctatcaaaaa attgttcatt ggcaaacagc actgaatctg caaaagaaaa
    40561 atcaggccta ccagcaattg ctccggcagc tgatggcaga ctgctacctg aaaaaaagtg
    40621 aatgcgatca atacttttct cctaaatatc aaaatatagc cgttgcagat tatattttgt
    40681 cgataagccc caatttaaaa tcgaaatctg cagaaatccg agagtttgag gaagcgttgc
    40741 gtaaaacaga ccagcatcaa gaaatctatt cgcttgttca aagctatctt catctgccac
    40801 gtatagctaa ggaaatcgac cagagtgatc aagaatggat acgagaagaa gtaaagcagc
    40861 atgctacttt cagaagactc caagccttat cgcaagaaac ccaagcgaca gctaaagaat
    40921 taaaaacccg cttgattgct tacagacaag gaaaacttga tgcactatgt atccagagca
    40981 ttcacaaaag taaaggtctt agttaccgaa atgtcttttt gattggttgt aacgaaggaa
    41041 gtttgcctta taacggagcg acagaaaaga aagtaatcga ctttaatgaa ataaaagcag
    41101 aaccagtaac gacgatagaa gaagaacgaa gactatttta tgttgcgatg actagagcaa
    41161 gaaatcgtct gtatctatgt gtacctcaaa tgaaaaattc aagaaaattg aaagtatcga
    41221 gatttatcaa agaaaccggg agtcgtgtga aaaaaggaaa gtgatagaag agagggtgtg
    41281 acagaagtgg tcagtttcaa gaaagaagaa ggaatgtacg aaaattgctt ctcaaatttt
    41341 tgtgaaattt cagcttattt tcgaagaagc tatttctgga acacagttta ttcggaaaag
    41401 ggaggtgtga caagaatttt gtcacacctc ccttatttat tttgaaaatg agaatactat
    41461 tatcaaaata gagaatatat agaaaaattc tcattattca aacgtaaata atcagttatt
    41521 ttgatttttt ttatatttta ttagctaata attggtattt taaaagaaat tactgtagaa
    41581 ttggattata attaaaaagg agtgagaaaa tgataaaagt atatacttcg cctagctgta
    41641 cttcctgtag aaaagcaaga gcatggttgc aagcgaatca acttgaattt gaagagaaga
    41701 atatttttgc cgaaccgtta acagaaagtg agatcaaaaa gatcttggca gcgactgaag
    41761 gaggagttca agatattatt tccactcggt cgaaaattta cgaaaagctg ggcatagatt
    41821 ttaacgaatt aactttaaag caaatgatcg tcttattcaa agaatatcct tcattattga
    41881 gacgacctat tttgattgat gaaaaaagaa tactaatcgg atttaatgaa gatgagatcc
    41941 ggtcatttgt ccctcgtgaa attcgatgtg ttgccagaaa tctgatctat ttacaaaaca
    42001 ataacatctt aaattcatag ggagggagcc ttcgtggaag tgaaagtcta tggatcagcg
    42061 cactgtgtaa caagtctgaa ggcgaaacaa tggttagaac accatcaatt gccttatcaa
    42121 tttgttgact tagaagaacg cgatctaagt acagaagaag cagaagaatt atgcagtttt
    42181 gaagaagtgc aagcagaaca gctatttgcg acttggtctg aggcttttca caacattgcg
    42241 attgaccttt cctgtgtagg aaaaaaacaa ctgatttttt tatgcacaca acataccaat
    42301 ctcctcagac gtcctttgat tattatcgat gaagttctat ttattggata caatgagcag
    42361 ttgatggaac agcttatctt aaataaatag actttaactg ttttaatcaa gtcactgagc
    42421 atttcataca gttgtaacag tcgaacactt agcatcaagc gtgttatgtg ttcttttttt
    42481 gactttattt ttctactata gagacatgct caatttatgt ggtcaaaatt caaatctagg
    42541 tggggatata gagttaaaaa tatattgaca tgtgtaaatt tacatgatat attcatttct
    42601 gttgttttaa gtagcaaagc aataaaatag tattttaaaa aacatataaa atagttgttg
    42661 acatgttaga aatgacatga taagataact gagttgttaa aaaagaacca cttgtgaagc
    42721 ttgattctat cgaaaaaaac ttcaaaaaag ttcttgacaa ataacaaatg ataagttatg
    42781 ataaatgagt tgctgtaaga tttcgaaaaa cgaaatcaaa aaaactttta aaaaagagtt
    42841 gacaattact tgtctctctg atatgatata aaagttgcta cggcagccaa aaacgaatcg
    42901 gggaacactc ctgatgaagt agacctttga aaactgaaca aagtaagaca aaccaaatgt
    42961 gtagggcgtc ttgattcaat tcaagacaac aaaca
//
LOCUS       DBBGSZ010000021        39680 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.021, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000021 DBBGSZ010000000
VERSION     DBBGSZ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 39680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.021"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(151..2304)
                     /locus_tag="ACIZE5_001544"
     CDS             complement(151..2304)
                     /locus_tag="ACIZE5_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HGC6108692.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(2598..3446)
                     /locus_tag="ACIZE5_001545"
     CDS             complement(2598..3446)
                     /locus_tag="ACIZE5_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGC6108693.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(3670..5610)
                     /gene="thrS"
                     /locus_tag="ACIZE5_001546"
     CDS             complement(3670..5610)
                     /gene="thrS"
                     /locus_tag="ACIZE5_001546"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HGC6108694.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDSDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(5947..6126)
                     /locus_tag="ACIZE5_001547"
     CDS             complement(5947..6126)
                     /locus_tag="ACIZE5_001547"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016862 - intramolecular oxidoreductase
                     activity, interconverting keto- and enol-groups [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxymuconate tautomerase"
                     /protein_id="HGC6108695.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(6173..7996)
                     /locus_tag="ACIZE5_001548"
     CDS             complement(6173..7996)
                     /locus_tag="ACIZE5_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGC6108696.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            8274..10553
                     /gene="helD"
                     /locus_tag="ACIZE5_001549"
     CDS             8274..10553
                     /gene="helD"
                     /locus_tag="ACIZE5_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase recycling motor HelD"
                     /protein_id="HGC6108697.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(10646..11293)
                     /locus_tag="ACIZE5_001550"
     CDS             complement(10646..11293)
                     /locus_tag="ACIZE5_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108698.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(11472..12191)
                     /locus_tag="ACIZE5_001551"
     CDS             complement(11472..12191)
                     /locus_tag="ACIZE5_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6108699.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(12322..13473)
                     /locus_tag="ACIZE5_001552"
     CDS             complement(12322..13473)
                     /locus_tag="ACIZE5_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGC6108700.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(13690..14430)
                     /locus_tag="ACIZE5_001553"
     CDS             complement(13690..14430)
                     /locus_tag="ACIZE5_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC6108701.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(14434..14757)
                     /gene="rsfS"
                     /locus_tag="ACIZE5_001554"
     CDS             complement(14434..14757)
                     /gene="rsfS"
                     /locus_tag="ACIZE5_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HGC6108702.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(14814..15407)
                     /gene="yqeK"
                     /locus_tag="ACIZE5_001555"
     CDS             complement(14814..15407)
                     /gene="yqeK"
                     /locus_tag="ACIZE5_001555"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HGC6108703.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(15391..16041)
                     /locus_tag="ACIZE5_001556"
     CDS             complement(15391..16041)
                     /locus_tag="ACIZE5_001556"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HGC6108704.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(16051..16362)
                     /gene="yhbY"
                     /locus_tag="ACIZE5_001557"
     CDS             complement(16051..16362)
                     /gene="yhbY"
                     /locus_tag="ACIZE5_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HGC6108705.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(16378..17487)
                     /gene="yqeH"
                     /locus_tag="ACIZE5_001558"
     CDS             complement(16378..17487)
                     /gene="yqeH"
                     /locus_tag="ACIZE5_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HGC6108706.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(17484..18011)
                     /locus_tag="ACIZE5_001559"
     CDS             complement(17484..18011)
                     /locus_tag="ACIZE5_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HGC6108707.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(18191..18976)
                     /locus_tag="ACIZE5_001560"
     CDS             complement(18191..18976)
                     /locus_tag="ACIZE5_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HGC6108708.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(18969..19838)
                     /gene="accD"
                     /locus_tag="ACIZE5_001561"
     CDS             complement(18969..19838)
                     /gene="accD"
                     /locus_tag="ACIZE5_001561"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HGC6108709.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(19839..21218)
                     /locus_tag="ACIZE5_001562"
     CDS             complement(19839..21218)
                     /locus_tag="ACIZE5_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HGC6108710.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(21226..21645)
                     /gene="fabZ"
                     /locus_tag="ACIZE5_001563"
     CDS             complement(21226..21645)
                     /gene="fabZ"
                     /locus_tag="ACIZE5_001563"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HGC6108711.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(21670..22146)
                     /gene="accB"
                     /locus_tag="ACIZE5_001564"
     CDS             complement(21670..22146)
                     /gene="accB"
                     /locus_tag="ACIZE5_001564"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HGC6108712.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(22149..23384)
                     /gene="fabF"
                     /locus_tag="ACIZE5_001565"
     CDS             complement(22149..23384)
                     /gene="fabF"
                     /locus_tag="ACIZE5_001565"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HGC6108713.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(23403..24140)
                     /gene="fabG"
                     /locus_tag="ACIZE5_001566"
     CDS             complement(23403..24140)
                     /gene="fabG"
                     /locus_tag="ACIZE5_001566"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HGC6108714.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(24152..25069)
                     /gene="fabD"
                     /locus_tag="ACIZE5_001567"
     CDS             complement(24152..25069)
                     /gene="fabD"
                     /locus_tag="ACIZE5_001567"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HGC6108715.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(25176..25400)
                     /locus_tag="ACIZE5_001568"
     CDS             complement(25176..25400)
                     /locus_tag="ACIZE5_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGC6108716.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(25453..26415)
                     /locus_tag="ACIZE5_001569"
     CDS             complement(25453..26415)
                     /locus_tag="ACIZE5_001569"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HGC6108717.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(26425..26865)
                     /locus_tag="ACIZE5_001570"
     CDS             complement(26425..26865)
                     /locus_tag="ACIZE5_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGC6108718.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            27171..28136
                     /locus_tag="ACIZE5_001571"
     CDS             27171..28136
                     /locus_tag="ACIZE5_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGC6108719.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(28193..28423)
                     /locus_tag="ACIZE5_001572"
     CDS             complement(28193..28423)
                     /locus_tag="ACIZE5_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HGC6108720.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(28509..28994)
                     /locus_tag="ACIZE5_001573"
     CDS             complement(28509..28994)
                     /locus_tag="ACIZE5_001573"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF026183.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HGC6108721.1"
                     /translation="MVGGEEAVYDQVLPLFKEFGTTFTLHGSAGKGQHTKMANQIMIA
                     GTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNYSPRILKEDYTPGFFVKHF
                     IKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDGTQALIKLWWPEGKIPEKK
                     S"
     gene            complement(28977..29395)
                     /locus_tag="ACIZE5_001574"
                     /pseudo
     CDS             complement(28977..29395)
                     /locus_tag="ACIZE5_001574"
                     /inference="COORDINATES: protein motif:HMM:NF015411.4"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
     gene            complement(29484..30707)
                     /locus_tag="ACIZE5_001575"
     CDS             complement(29484..30707)
                     /locus_tag="ACIZE5_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGC6108722.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(30724..31770)
                     /locus_tag="ACIZE5_001576"
     CDS             complement(30724..31770)
                     /locus_tag="ACIZE5_001576"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGC6108723.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(31934..33661)
                     /gene="ptsP"
                     /locus_tag="ACIZE5_001577"
     CDS             complement(31934..33661)
                     /gene="ptsP"
                     /locus_tag="ACIZE5_001577"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HGC6108724.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(33661..33927)
                     /locus_tag="ACIZE5_001578"
     CDS             complement(33661..33927)
                     /locus_tag="ACIZE5_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HGC6108725.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            34406..36640
                     /locus_tag="ACIZE5_001579"
     CDS             34406..36640
                     /locus_tag="ACIZE5_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC6108726.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            36788..37108
                     /locus_tag="ACIZE5_001580"
     CDS             36788..37108
                     /locus_tag="ACIZE5_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HGC6108727.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(37313..37537)
                     /locus_tag="ACIZE5_001581"
     CDS             complement(37313..37537)
                     /locus_tag="ACIZE5_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HGC6108728.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(37735..39315)
                     /locus_tag="ACIZE5_001582"
     CDS             complement(37735..39315)
                     /locus_tag="ACIZE5_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HGC6108729.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
BASE COUNT        11138 a         8569 c         6889 g        13084 t
ORIGIN      
        1 aatttttgtc acaacctttt ttgccgagta aacggtgttc aaaagccagt ttctcggtat
       61 gaagtcaaat ttaagcaaaa atgtgagaag ctattttcac aaaatttttc ttcatactcg
      121 aaactaagcg gctttttcac gacctctttt ttattttgcc atgaacatat cataatacgc
      181 gtccattatt tctttagcaa tcgtcaagtt tatgtggtct tgttcgtcta ataagttcgg
      241 caagacaaca ctgatggcaa tttccggatt gtctgttggt ccgtatgcca cgatattact
      301 attgactgtc gcaatatctg gatgaccttc cgcaaccgtt tctgcagtcc ctgtttttgc
      361 ggaaaggtcc attttcgcac tggctaatgg tttggctgtt gtgtaaggat cggtaccatg
      421 gacaacttgg tggaatcctt cacggaggat cgccatattt tctgcagaaa tattgaccgt
      481 attttctact gttgtgccaa tttctttctt cacttcaccc aagtttccat tttcgtcatt
      541 gccatagatc gctttgacta ggtgcggctg tactcgtttc ccgccattag cgactgttga
      601 agcatattga gctaattgga ttggtgtata tgtgtcaaac tgtccaaatg ccaaatcggt
      661 aaagttacct ggagcatacc attctttgcc attatccgca ttgaacttct tcatataatc
      721 aacagaacgt gagatcccag gagattcatt cggcaaatcg atcccagtcg ttgtaccaag
      781 accaaactct ttgaaagagt ctctcaattg ctgataagct ttagcttctt catctaaact
      841 aggtagtccc attccaggtg tatagtctag tcctaacatc tttaacgcca ctttgatcat
      901 atacgtatta gaagacaatt ccgatgcttt gactgcatca agagcaactt gtccgcttcg
      961 attaaagaca gagctttttt ctgaagcacc ttgcagacga atcggctcat caatcaaaac
     1021 ttgatttccg ctgatcgcgt tacttgccca gcctgctgtc aaagtaccag ccttgactac
     1081 agaccctgga tcaaaggcgc tagtaatcgt gcctaaagca ttctcggtga tttctttgga
     1141 accttgttca tgactgaaac cagtcattgc tagcacttct cctgtctgag gattcatagc
     1201 cactgcataa gcaccaggcg aatactgtgc tttgccgttg ttgatcaatg tttgataatt
     1261 ccttttcaaa atttcttcta cttttgattg gaattctgca ttcatagata acattaaatt
     1321 agaacctttt tccccagaga agatttcttt ttgattcgaa acatttcctt cattatcaag
     1381 ggaaacttca tattgggttt tggttccttg caggacatct tcatattgtt tttccaaata
     1441 actttgtcct acacggtcat tccgagaata accttttgct aggtatttct ctgcttcatc
     1501 tgctggaagt ccttgctttt cagtcgtcac actgccaaga atacttttca gtgaacttgc
     1561 tgcattatat tctcgtgtcc agtctgtgcc agtcgaaact cctggaagtt cagaagcgcg
     1621 ttctgccaca acagctaact cttgatcagt aacaccagag tttttgatat agacagtgtt
     1681 taattcatat gcactattca tccgtttaaa gatggtagca atttttaatt gctcctcgtt
     1741 taaattaatc tcatcagctg tgactttatt gaccatcgca ctatattgtt cgctgttccc
     1801 taattgcttt tcttttgccg aaagtctttt tgtggcttct ttcaaatgtt tgggatcagc
     1861 cagccaaaaa tcttttttat ctctatctgt cagattttca tctaccggaa catcgatcag
     1921 cgagttcagc ttcgttgcga tttcaagcaa atctttagcc gtaacttgtg ttcctctcgt
     1981 atatgtgatg gcctgattcg ctttattcgt aactaaagct tttcctgtgg agtcgtagat
     2041 cattccgcga ggagtacttt cttggaccgt aatcgtagaa gtagacttca ctcgcgcctc
     2101 catctcttcg ccgttcacga tctgcaaata acccaatcta gcaatcaacg caacaaataa
     2161 cgtaaatata atgaaaaaaa gaaaatttaa gcgaaaagga acatgggacc ggcgaaacgt
     2221 tttgttctta ggttcttgtg caccttttct tattttttct aaccaagaag tatttaatat
     2281 ttttttcata aaatctttca tcatttccta tccttccgcc tatttacatt catgcttcat
     2341 tgtacccaaa aacttcttaa taaaaaagaa aaaatgggcg gagcaagaaa ttctttacct
     2401 aatttcaaga taaaatcaac tttttgtttc acagcaatca cttaaagtta catatccaac
     2461 tatttttttc attaaaaaat aaacttattt ttgaaaatta tgttttctta agtcgtgaaa
     2521 cactttgatg gatcatttat ttgtggaaaa ctacgttttg ttattctaaa aaacttatat
     2581 aaaaaatagt aaggttttta tttcgaatcc ataaaatatt cttggattgc ttctcgtgtt
     2641 tttttcactt tttcgctaag cttttcgttt ttagccatat agaaataaaa aatgatatcg
     2701 atcgtagcaa attgggccaa aagtgaatta gttgccgcac ttcgattcgt gatttctttt
     2761 ggtctagatg tttgtacgag tacatcggct atcttgctaa gcgggttatt tccaaattgc
     2821 gtcaacgcaa tgatttcgat attcatgctt ttcgccagct cggctaatgc gactacatct
     2881 gcacttctac ctgagtttga aacaagccaa agcactttct ttttctcatt gctgacaagt
     2941 tgcgggagca agacgtggat atctttttca aaaatgattg gcttaccgac acgagaccat
     3001 ttttgcagaa tatcttctac tactaaagaa gaggcgccaa ccccatataa aaaaacagtc
     3061 tctgccgatt ccaaacactc tacgactttt tggatcgttt cttcttctag aatatctact
     3121 gtttctttta tcgctacttg tgcattgtta ccaagtttgt ttttgataga gtaaaaggac
     3181 tcatttgctt ctatatcact aaaaccttca tcgattccag tctgtagttc tgttgaaatc
     3241 gtgattttga agtccgtcag actttgaaaa ccgatttttt tggaaaaacg tacaactgtc
     3301 ggcgcactca acccggaagc ttctgctaat tcattagctg tcattgtagg gaccttctca
     3361 atattaccga taatgtagtt ggccaacttt ttttctgctg aagaataatc ttccatcata
     3421 ctttcaatac gactaattac gctcataagt tcctccaccc ttttaatgat agtctatgta
     3481 agtataccat atcagaccct tattcacggt cgtatactgg ataaaaaaca aaaaaacaat
     3541 ccgcccaaca gaatatctta tcccatcaat cccacagatt ctattgagca tctgtgtctt
     3601 tgaggaatac ctgttatcta ttgttcggat tgctttctat ctactacttt tttacaggaa
     3661 atttacctat tagttttctc tgctgtaatt tttgacttct gcttccatag catcaataaa
     3721 gatattcaaa tcttctacag ctgtttcttt acttccataa cgacgtacgt tcactgttgc
     3781 atcttccaat tccttgtctc caacaactaa ttggtaaggg atcttttgtg tttgagaggc
     3841 acgtatctta tagcccattt tttcattacg atcatcaact tctacacgca accccttcat
     3901 ttgcaaacgt tctttgattt cataagcata atcgccatgt gcatcaacag aaacagggat
     3961 gattgttgct tgtataggtg ccaaccatgt tggaaaagcg cctttgtata cttctgttaa
     4021 ataagcgaca aaacgttcca ttgtagaaac aattccgcgg tggataacta ctggacgatg
     4081 cgtattttcc ccgtcttctc caacatatgt caaatcaaag cgctctggca ataagaagtc
     4141 taattgtata gttgataatg tttcttctgt accaagagct gttttgactt gaacatctag
     4201 ttttggtccg taaaaggctg cctcgccttc tgcttcaaag taatctagtt ctaattcatc
     4261 catagcggct ttcagcattg cttgggcttt ttcccacatt gcgtcatcat caaaatattt
     4321 atctgtattg tttggatcgc gatagctcaa gcggaaacga taatctgtaa tattgaagtc
     4381 agcatatact gccaccatca attcaagcgt acgtttaaat tcatctttga tttgatcagg
     4441 acgaacaaat gtatgaccat cattcaacgt catttctcgt acacgttgta aacctgacaa
     4501 agcacctgat ttttcatagc gatgcatcat tcctaattca gcgatacgaa ttggtaattc
     4561 acgataagaa tggatcgtgt ttttgtagac catcatgtga tgagggcagt tcattgggcg
     4621 aagaacaagc atttcgccat ctcccatatc cattggcggg aacatgtctt cttgataatg
     4681 atcccagtgt ccagatgttt tgtacaactc aacatctccc attattggtg tatatacatg
     4741 ttggtaacct agactaactt ctttgtctac gatataacgt tcgatcgtgc gtcggattgt
     4801 tgcccctttt ggaagccaga atggcaaacc agaacctact tctggggaaa ccatgaacaa
     4861 gtcaagttct tttcctagtt tacgatggtc tctttctttt gcttcttcac ggagacggat
     4921 atattctttc aaagctttct tgtcaaaaaa ggctgtcccg tatacacgtt gcatcatttg
     4981 attgtttgag tttccacgcc aataagcacc tgccactgat aataatttaa atacttgtat
     5041 acggccagtg gatggaacat gtggtccacg acacaaatcg atgaattcgc cttgttgata
     5101 agcagtaatc acttcttctt ctggcaattc actaatcagt tctactttgt acggatcact
     5161 tgcaaaaatt tctaatgctt cctgttttga aagaacacgg cgttcgatcg gcagattttc
     5221 tttgacgatt ttcatcattt ctgcttcgat tgccggcaaa tcttctgcag ttacttggtt
     5281 ttgtccatta tctgaatcgt agtaaaaccc tgaatcgata gctggtccaa cgccaaagtg
     5341 gatatttgga tagaggcgac gcatggcttg ggccatcaaa tgagctgctg aatgacggac
     5401 taagccaagt gcatcttcat ggtctggtgt gatgatctca atacttgcat cttcctcgat
     5461 tggacgagtc aaatcaacga gttttccgtt cactttacca gctaaagctt tttttgctaa
     5521 gctttttgaa atgctttcag caattgccaa tgttgttgtt ccagactcaa attctttgac
     5581 tgcaccatct ggaaaagtaa tttttatcat aatagtttcc tccttgaaat gttttgattg
     5641 atcagatcat caagctgaaa aacaaaaaaa tcctagcatc tcttgaaaag agatactagg
     5701 acgaaaagtt cgtggttcca cctaatgttc aaacgcaaat gcgttcctca agcgttgtaa
     5761 cggtccgacc gcccttgctt caacaagggt ttcgaaagtg gtcatccttt ggttttctcc
     5821 tggaaaagtt tcagcctagc ttttcctctc ttatcgaaga ctctcaaatt cagttggctt
     5881 tctcatcaat caattatgtg tttatttaac cactaataaa tagaaaaatc aagtgggaaa
     5941 ctaaacttat tttttccatt ccccatttac accgtatgtt ccttttttca tctcattgat
     6001 gatgacatgg atgtgttctt ttggtgcctg cgtgttttta tgaacagctt ccgtgatatc
     6061 tttcatcata ttttctaatt gttccggact gcgaccttct actaattcga catgtacgaa
     6121 tggcataatg ctctctcctc tttctgatcg ttcttttttc aactcgattc tatcatacta
     6181 tgtttgtctt gggtactgaa tcaggaaaaa tggctggatc tttttttgct ctcaaggcac
     6241 tcaaaataga gaccgtatcc acgacttctt gcaaaacagc tccgaataat gcggggatta
     6301 gtcccgtact tgcaattaac atcaaaaaaa tacaaataaa gatgccaatc agtacagact
     6361 gtttcgctat tctcatcgta tctcttgaaa tcactactgc ttttgctaca cgcaagagat
     6421 catctttcaa gatgaccgca tctgcacttt cactagcagc tgtagaacca tgagccccca
     6481 ttgcaatacc gatatctgca gcagcaagtg ctggtgcgtc attcacgccg tctcctacca
     6541 tcgcaacagg tctttgatct ttagggatac tttctaaaat ggtcagttta tcttgaggca
     6601 agctacgggc atgtacagaa tctaattgga ctttttctgc aatcgtttga gcaatggcag
     6661 atccatcccc ggtgatcatc atcaaatttt tcacatcaag ttttcttagc tccttgattg
     6721 tctttgctgc ttctgggcga atctgatccg aaaataggat cgttcctgca aaagatcgat
     6781 caattgttac atagattgct gtattggacg tttctatttc ttcagctgaa acaaaagagg
     6841 cacgtccaat ctttacttca tgattattga ctactgcttg gattccttga ccggtcactt
     6901 ctttcagttg actaacagga tacagttggc tgtttttcac gttgttcact aacgaacgag
     6961 ctaagatatg gctagattcc tgttctgcac tagctgcata cagaagtagc tcttcttttt
     7021 ttattccatt gactggctga atcgcctcta cttccaatat ccctttggta agcgttcctg
     7081 ttttatcaaa agcaatcgtt tttgtacgtg cgagcttttc aatcgttgtt ccagttttta
     7141 caacgatccc gtttttactt gaacggctca ttcctgcaac taaagcaatg ggcgcagcta
     7201 gaatcagtgg acaaggtgat gccactacca gtacctcagc aaatcgtaaa gggtcttttg
     7261 agaaccacca agaaatacca ccgatcaaat aagcaatcaa cgtgaaaggg actgcataac
     7321 gatcagctaa acggacaaat cgggcaggct tttcttttga ttcttcgact agtttaataa
     7381 tcatttgata ctggctgtct gcggcacgtt tttcagcgat catttggatc gatccgtctc
     7441 catttaaaga ccctgacata atctgatctc caggtttctt ggtttccggg cgggactcac
     7501 ctgtcaaaga agattcatcg accgaagatt ctcctttggt cactcgacca tctgcgggta
     7561 caagttcgcc aggcttgact agtaactggt catcaatatt tatttcatcg attactatat
     7621 cctgcaattt tccttctttg aatcgatggg caattcttgg ggtgttatct aacaaagact
     7681 gcagttcttt acccgctcgt ttattcgcgt aatcctctag actatctccg cccgtaagca
     7741 tgatcaatat catcaaacta gcccagtatt ctttgacggc taatgttgca aggattgcgg
     7801 taatcgctaa tacatctacg ccatatcttc ctgaacgtaa cgtcttgatc atttccaaaa
     7861 acatcaagaa ggcgagaatc cctccagtaa atgcgacaat cgcaaatgca agggccggct
     7921 ggtgaaaaac aaattcactt aataaagcta tcccaccaat aagcaaagta agtaaaaatt
     7981 ttttgaaatg tgtcattgtt ttttctcctc ttttatgtga cttagagagg ttagtaataa
     8041 atttccagct gcctctttca tcttaagcat agtccttgac tagcactttt taaaacaata
     8101 ggccttaatt gaaaacaact atcactatca gcgtttccaa aattcatcag ttctacaaac
     8161 aaaaatattc agcaaggatt actttttcga ttcatcagtt aaaaagtacc ttttttcgaa
     8221 aaactatgct atacttttaa ttcgttattt acggcggaag gagcaaacat gcgatgaatg
     8281 agaaacaact agaacaaacg cacgtggatg aaacgatcga actaatccag atcgaacaaa
     8341 atatgctgga tacaaaacaa caagaattga ctcaggaaat gaatcattcg acaaaagaca
     8401 cagctaatca caagattcga gctggttcca atgaagcttt ttatgaatct gctgttgaat
     8461 atcgccaaca tgagcaggaa ttgcttttga aataccatac tcttgaagca cagcaaaaac
     8521 gcctgcaaac gttgtctgtc atgaaagata gtccttattt tgcccgtatc gactttaaag
     8581 aagaccgtga aacagaaaca ttatatctag gtatcgcttc tttaagagat ctggcagaag
     8641 aaacaatcgt tattgactgg cgcgcaccaa ttgccaatct ttattatgaa ggtgagattg
     8701 gtcccgcatt ttatgaaact gaaacagata gaatagatgt cgatctgcag ttgaaacgac
     8761 aatttaaaat ccaagaagga cgtattttat ctatggtaga tacgtcggaa gtaatcaatg
     8821 atgacttttt gctagagata ttggatgaat catcaagcaa ccatatgaaa aacatcgtct
     8881 ctacgataca aaaagcacaa aatgcaatca ttcgggacac aacaagtaaa gtaatgctga
     8941 ttgaaggaat cgccggaagt ggaaagacat ccgctttgct tcaacgtatt gcttttctgt
     9001 tgtatcataa tcgcaagtgg ctcgaggctg aaaacgttct tctattttca cccaaccatt
     9061 tgttttctga ttacatctcg actgtattgc cttcattagg tgaaagcggc gtgcctacac
     9121 agacattcaa aaattatttg gtgcagctgc tgccagagtt ttctttacta gatgaacagc
     9181 aacaagaaag tggttttttg ctaggggaaa aagatccgat acaagtgatg aaaagcggat
     9241 tgaccttagt cgatcagatt gatcgctata tccaaggcat cacaaactac ggtcccttgt
     9301 tccgtgatat gaaaataaat ggccgtacga tcctatcaaa ggaatcgatt cgccaatggt
     9361 ataaagaaac aaatgaacaa ttacctttac atcatagact ttctctatta caaacgaagc
     9421 tcctgaaaaa attaggcggt ctgcaaaaag acgaaacacg tcagcaatgg gtcaaagatc
     9481 tggcggaaga acagctccaa gaactatacg caacagatcc aaatcttgaa tatacagaac
     9541 aaaaggagcg ttcattacgt aaaaaactgg ccaaccaaat cgtacgtaaa agattccgtc
     9601 gaatccatcg agggatcatg aattatcaat ttgtcaatat aacgaaacaa tatctccact
     9661 ttctacaaac tgtgccactt tctcttctaa cacgacataa aatcagcgag accaggtggc
     9721 aggaacattt gacaactgtt cgtacacact tgcgtcaaag agaattgcgt caagaggatg
     9781 ctgtactatt ctttttactg atgcgccgaa catatccagt gacggttaca cacaaagctc
     9841 gctatatctt tattgatgaa atgcaggatt tcgcaccatc acaagtggca ttgctgcaag
     9901 ccttgttccc aaaagcaaat ttgactttct gtggagatct aaatcaaaat gtctttggaa
     9961 atgaaacgat cgttggatca ttggaagacc ttttcgtgga ccgtgaagtc actcgtttcc
    10021 aattaacgac aagctatcgc tccacaaaag aaatcactga ttttgctaat cattttattg
    10081 tgaaagaaca tcaagtagaa acaacagcaa gaaaaggaga ccttcctttg ctcatccaag
    10141 gaacaacaga tgatatcaaa ttgaattggt tagcagatac cattcgaacg actcagggaa
    10201 aagcccggta ttggcgtaca gcaatcatag ctaaaacaca agaagaatgc gaagctcttt
    10261 atgctcaact gccagacgag ttgaaacaac aagtccagct gattttaaat gagagtgact
    10321 ttatgaagcg ttccattatt ttacttccag cctttttagc aaaaggtctg gagtttgacc
    10381 gagttttctt gtgggatgta gatgcagaac atttttcttc tcagcaagac aaattgatcc
    10441 tttacaccat gtgtacacgt gcgatgcatg aattgaccct ttttacctcc aataatgaaa
    10501 gtcctttgtt aaacaatatg gatatttcat cttatgagaa aaaagtactg taagtaaaaa
    10561 gacaactgct atcattaatg ttagcagttg tctttttatt tacaataata attgcagaaa
    10621 aagtaattca atcatttaag gtcatttatt ctatatataa atccaaatct gtttcaggat
    10681 attttaattt gacaagcgaa ataatcattt tcagttcttc catgttttct ggatattctg
    10741 ggtcaaatac cttgctatga cggccaatcc cgccattgtc gatcaatcgg taaattcgat
    10801 tccattcaat gaattggtca attgattgga aattgctgat tggatagccg ccacaatcca
    10861 aaatctctga tacacgaaat gctaggtatg cactatcgat cactttattt tttttcgtgt
    10921 ctatcttctc atttctttcg ataagaattt tttcaggacg atgtttcaag ctccactcta
    10981 atagtagaaa gaaagcctcc atccgatact cttcttcaaa taaccgaaag gctgaatcag
    11041 aacgacgaaa aagcagcgga atcagataat tttgtctata aatcagcatt ggtgcgcggt
    11101 ccaccataca ctctaaataa cggttcagat accctgtacc gacatagttt cctaatcgat
    11161 agccttcaac gccgaatctt gcgtattttt gcgctaattt tgaacaatca gttacgttca
    11221 cagctaactc ttctactttg cggtaaccgc ttaagatacg ttcaaaaggt tctaaagtga
    11281 tttttgcttc catattcttc cccgtccatc ttccacatac ttcatatcat ttcacatgat
    11341 acttatgctc tcatcatacc acaggttgaa ttagaaaaga aaataaatca cacaaaaaag
    11401 caagacaatc tgttagtgag attgtcttgc ttttcgaaaa agactgaata cttttcgtta
    11461 aaactggttg cttagtcttc taatgccaca ttatggaaca catgctgtac atcttctaga
    11521 tcttccagtg catcaatcat tttttcaaat gtttcttgat cttctggaga tagtgttacc
    11581 tcgttttgag ggatcatttg gatctcagcg attgaaaaat cagtgattcc tttttctttt
    11641 aatgcttctt gtatactatg gaaatccgct acttcaccgt aaacgatgat ttgtccttct
    11701 tcttccatta catcgcgaac atcgatgtct ttttccatta ggtattcaag gatctcgtca
    11761 gcgtcttctc ctgcaaaagc aaagattgct gtattgtcaa acatgtaaga aaccgctccg
    11821 gaaacaccca tgttcccgcc atttttccca aatgctgccc gtacgtctgc tgctgttcga
    11881 ttcacattgt tcgtcaatgt atcaacaatc accattgagc cgcttggtcc aaatccttca
    11941 tagcgcaatt cagagtatgt ttcatctcct gcaccttttg ctttttcgat tgctcggtca
    12001 ataatatgtt ttggtacatt ataagtttta gcgcgatcaa tgacgaaacg tagtttttgg
    12061 tttgcatgcg gatcaggatc acctgatttt gctgccgcgt agatttcaat cccaaatttt
    12121 gcataaatcc ggctattatt agcatcttta gcagttttct ttgctacgat atttgcccat
    12181 ttacgtccca tattttcact tcgctttctg atttgatagt ttcataacgc aaaaacgtcc
    12241 tgttccatta tacttgtgaa tcacgattct gtgaagcttt ttttctttct tccttcattc
    12301 ttctcatttt tagtcaatta tctatactcg gattgggatt tgcccgaaat tctgttccgg
    12361 aatattgcct cccaattgat agatttgatc acttctaact aacagttccg cttcttgtgc
    12421 ctcttttttt ccgattcggg aataaataga aatctctttt ttttctttta agaatcttct
    12481 tccagcatcg gtaaatccaa gtagtcgaag ataattttta ttttgttgga caggaatctc
    12541 ttgctttttg atattcagca agacataaca agataatcgt tggatccgtg tccatgtata
    12601 tctttttgtt tttacctttg acacaaaatc ctcaaaacta tcagcagttg cagctgctgt
    12661 tttcatgcgc gattctattc cttcggtcat ctgatagata tctgtcagtt ccagcaaagt
    12721 agaagataac aaccgataac gcaaatacgg ccaataagat tcccaagtct gcagcgaaca
    12781 agttgaaaga tcttcttctg tctgaggcgg cacaagtcca gctattcttt ttccttcttc
    12841 taacgcatgg cgaatggctg ttgcactggc tatcctctga tctgtgatga ttttttcatg
    12901 atagcctgca cttttacgtc ggatcggatg taattccata gggtggacat acttggcatt
    12961 ttcctttgca taacttaatc ccaagatatg atttggcgaa gaaaaatcaa gcgtaatatc
    13021 gggatacaga ctgcgaaaaa cctcagtcat tttttgcgga taactatacg tttgatcaga
    13081 cagttcttga aatgcctctt ctatcctatc ttgattctct tggacaaagc gtccgaaact
    13141 gctgtaatca aacgaagtct cttcttctgt tccaaaacac aaactgtcac agtccagtgt
    13201 ttgcaagatt tttactgcac ctttagcaaa atagtcagct gactgaaccg cccattcgac
    13261 gggaagctcc actactaaat ccacaccatt ttgtaaagct tcattcgcgc gatgccattt
    13321 atcgatgata gccggttcgc ctctttgcaa aaaattcccg ctcattacag caatgacgac
    13381 ctctgctcct gttatttttc gtgccatttc cacatgatag cgatgtccat tgtgaaaagg
    13441 attgtactct acgataatcc cgcagctttt catgcgcatc ctccttcata gttatcgata
    13501 aaaaagaaat agagacaagt aaaaaaaggc aaaaatcgga aaaaataccc gaactatata
    13561 aactattctc gcaaacacaa tacttctgcg acgaaaagct gcactgcaag agcaatgcct
    13621 atatcgttcg gatatataat ttatgttgaa gatttattct tttcttgtta actcgagcag
    13681 gcaaaaccgc tagtctttgt atgctacaaa gaaccagcgc tttgatttct ctgatgctgc
    13741 ttcgtctgta aaatcagaaa atgcttcgac tttcgaaaag ccgctgtttt ccagcattct
    13801 taaataactt tccaatggat aggtacgctc ttgatgtagt tcatcttcac gaataaatcg
    13861 accagaccct tcttgttctt caacgaaaaa ggtaagaaaa tgttcgatgc tgtgtttctc
    13921 gcttcctgga taactatccc acaaaaaagc aaaattatcc ccttgataat gatagctata
    13981 ttctggaaaa acctcatcta cttgataggt ggagtgtacg tcaaataaaa atcggccatt
    14041 ttcttctaac gcttgataga cttcatcaaa cacttgctgt acctcttgtc tatttttcat
    14101 atagcacagc gaatcagaaa aacaggtaat tgcctgatat tgtccgattt ctgataaatc
    14161 gagcatattg ccttccacaa attggatcga tgcgtcttct tcatatgctc gctggctggc
    14221 aatcatcaac atctcttctg aaaggtctaa ccctgtcact ttatatccat cttttgcaaa
    14281 ggcaaccgct aatgctccag taccgcatgc cagttccaaa atattttttg tgtcttcttg
    14341 taaatgacgt ttcgaaaaag ctaaccattg ctgataaagt gtttcgtcca tcacttcatc
    14401 gtaaatgaaa gcaaatgttt cataagccat atgttaatcc aaccattcac taagatcgac
    14461 tagcggagca tctgaccata gtttttccag attatagaaa tttcgttctg gcgcatggaa
    14521 aacatgtacg atcacatctc caagatcgat caatacccat tttccgcctt cttttccttc
    14581 aatacgtttt acttcatatt tgttttcttc ttctttatca atgatttctt ctgtaattgc
    14641 gttgatttga cgttcgctat ttgctgaaca gatcatgaaa taatctgcca acaaggaaac
    14701 atttcgaacg tctaaagcga taatgtcttc tgcccgtttt gaatctgctg cttcaatcgc
    14761 aatttttaat tgttctttac tatctatgat gatttcctcc taatatgagc agcttatttt
    14821 tttgctaccc agtaattata tgtttcgatt gtttttggat aaatctgttg ttcttgcgca
    14881 agcaaatggg ccaatgtatg ttttgtttca aatgctacag cttcgtctag atcagcccat
    14941 gcaatggctc gtgcatcttg taccccagga aaatctcgac ctggttcaat atagtctgct
    15001 acataaatga ttttgtcaag gagactcatc ttagcagccc cagtcgtatg cacccggatt
    15061 gcatgaagaa tctctgcatc ggtgattcct aattcccgct ctacaaacga agcgccaaca
    15121 agaccatgcc agattgcatt attataattc aataactccg gatcaaaacc gtctcttacg
    15181 attaccattt tgaactcctc atctggtcgt tcttttgcat aatcatgtgt caatgcagca
    15241 atactagctt tttcaggaga agcaccgtat tttttggcaa gagccacggc tgtttcttct
    15301 actccaagca catgcttgaa gcgttgttcg ctcattctca tctgtatttt ttgcatcagg
    15361 ttttctctag aataagcagt atattcatta ctatagtcca tattcataca acccttcatt
    15421 ttgaatataa tcaattactt tatctggaac aaggtagcgg atagaacagc cttctttgat
    15481 cttttgacgt attttcgtgg aactgatgtc gatctcaggt acatctaccc aaattacagg
    15541 atatggagta tccgttgtgt atcctggtcg acgtataccc acaaagttga ccatagaagt
    15601 cagctcatcg attttatacc attttggcaa atattctacc atatccccac cgataataaa
    15661 gtaataatct gtatccggat tgttttgcgt caattccttc atagtatcat aggtgtaact
    15721 tttcccacca cgagctaatt caatcgtttc aatctgcaaa aaaggattgt cttccaccgc
    15781 taattccaac atgttgagtc gatgttttgc atcaatcgtc tgtttctcat caacatgagg
    15841 tggctgataa gaaggcatca aaaatacgcg gtcaagacct aaattccggc cagcttgttc
    15901 agccatcact aaatgtgcaa ggtgaacggg attgaatgtt ccgcccaaga tccctacttg
    15961 ctttttcttc tctaagaatt gaggcatttc ttcaggaaat aattgtgaac gaacaaatgt
    16021 cttagcttgc gtattcatca tggtcactcc ttatattgct tttacttctt ttgatagcct
    16081 ttgatacttt tcttttgtgg aaggtttgta taatacaata acacgtccaa tgatttggac
    16141 gatttcgcaa tctatttctt tttctaatac ttgagctgct tcttctgcaa tctcatctgt
    16201 attttgaagt aacgatactt tgatcagttc tcttttttct aaagcttctt caatttgaac
    16261 gatcattgct gaattgatcc caccttttcc gatttgaaaa atcggctgaa gatgatgcgc
    16321 tttgctacgt aaaaaacgct tttgttttcc tcttaaactc ataattttcc ttcttcctta
    16381 aatcaatgct ttgcgtttca atacatctac accctttggc gcccagcccg caattactac
    16441 tggcgctgtt acagtgatcc agcctagacc ggcaaaaacg atgtctgttt tttctttcac
    16501 agaaaactca aaacgaacaa gctccggaaa tgcctcgact tcatcaggac gaggaggctg
    16561 taataatcca cctacatgtt tttgataaaa ttcgtctgct ttttccagtt tcgttcgatg
    16621 aatatttaca tcatttgaca cataagcaat aaatgaagca cgattgccgc tgataaaatc
    16681 aaatcttgca agtccgccca agaaaagtgt ttgcccttca ttcagctgat aaactttagg
    16741 tttgatttct tttaacggtg caatgatccg caaatctttt ttacctaagt agtgcgccat
    16801 ttgatggcga tggataattc ccggtgtatc aatcaaaaaa tgcccgtcat ctaaaggaat
    16861 ctcgatttta tccaaggtcg ttcctggaaa ctgcgaagtt gtgattacat cttgtactcc
    16921 cgctgtattt ttgatgattt gattgataag cgtcgatttt ccgacatttg ttactccgac
    16981 gatatagaca tcccgtccat cgcggtattc ttcgattttt tctaatagtt ccgtcatctc
    17041 atgagatttc ttagcactag ttaataatac atctactgga cgaattcctg cttcgtaagc
    17101 acgttccttc atccattgtg ttaatttagt ttttttcaat gatttaggta atatatccac
    17161 tttgttccca actaaaagta ctggattgtc accgacaaaa cggtgtagtc ctgggattag
    17221 tgaaccattg aagtcaaaaa tatccaccac attgacgatc aatgcatctt tttgccctaa
    17281 ttcattcagt aagcgcaaaa agtcgtcatc cgtcaatgag acatcttggg tctcattata
    17341 atggcgtaat ctgaaacaac gctgacaata gacttccccg gaagctaaac ctttttccaa
    17401 agccgtttgc ggcgtgtatc ctaattcacc gggtttgttt gtttgtataa cggcaccaca
    17461 gccgatacat tgtaattctt ctgtcattcg attccacctc gccagcccat atcagggtgt
    17521 tttgctaata gataggccat aattcttttt tcccaaaaac gattaaattg tgtcttccaa
    17581 ctatctgttg cgataatggg ttttacaagg atgctacgta tccctgcacg attggctcca
    17641 cgtatatcag tcataatctg atcgcctacc attactatct catcatctgc taaatccaat
    17701 tgtttctttg ctatgttgat ccctcttgct aaaggtttca ttgctcgtgc aacatacaaa
    17761 agatcaaatt tttcaatcgc tcgcgcgaca cgttttgaat tattgtttga aacaacaaca
    17821 acagggattc ctgcattttt catttctaaa atccaagtaa gcaactcttc tgttccatct
    17881 ggattattcc atgcaatcaa cgtattgtct aaatcggtca atactgcttt gatgcctaga
    17941 ttctttaatt gggcaggtgt aatctgatag atggcttcta ccatccatgt tggtttgtaa
    18001 tttgaaaaca tgctgtctcc tcatctgcaa aaaatgaagg agcacataaa gtactcctca
    18061 accccgtatt atactgcata tcagcaaaaa aaactacctc tatactcgtt cgtctttcag
    18121 aaaaagcatt tctttacaaa atgaccaaaa ataaagattg atcacagaaa aatttagaaa
    18181 caaaaaacaa ctaatattgg cggaacctct tgtatcgttt ttccagtaat ttatgctgat
    18241 ctaatcgaac aagttccgtc aatctttcaa tcaacgcttt tttcataatg tgtgcgactt
    18301 tatatcgtgg caactgctcg ccgttgaacg tttcaggaat aactcgatca acgattccta
    18361 actcgcgtag ttctggcgca gtaattttca tcaactcagc tgcttctgcg gcgcgactac
    18421 cgtctttcca caaaatcgac gcaaatcctt ctggagaaag cacagcataa atcgtttctt
    18481 ccagcatcca gacttcatcc gctaaaccta gagcaagggc accgccactt ccaccttcac
    18541 caatgatgat ggcgatgatc ggtaccttta aatcagacat ttcgagcaga tttctggcaa
    18601 tagcctctcc ttcgccgcgc tcttctgctc ctacaccgca atatgcacct gctgtattga
    18661 tcaaggtaat caccggtcta ttgaactttt ccgcttgttt catcagtcgt aaagcttttc
    18721 gatagccttc aggatgggga gaaccaaaat ttctgcggat attttcctgc agatcccgtc
    18781 ctttttgaat accgatcact gttaccggtt tgccatctaa tcgagcgatt ccaccaacaa
    18841 tcgcttcgtc atctgcaaat aaacgatcac catggcattc ctcgaaagaa tcgaagatct
    18901 cttcaaaaaa atccaagctt gtccatcgtt ctttagctct tgctaactga acgacatcat
    18961 gtgctgtctt atccacgatc tatccatcct ttctgtgtat gcaattcaag aagcgtatgg
    19021 attttctgtt tcaattccat gcggggaaca atctgatcga caaaaccatg agataataag
    19081 aattcagcct tttggaaatc ttctggaagt tcctgcttga tcgtctgttc gatgacgcgt
    19141 cttccagcaa aaccgatcaa gctttggggt tctgctagaa taatatcgcc ttccattgca
    19201 aaactggcag ttactcctcc ggtcgtcggg tccgttaaaa cagttagata aaaaagacct
    19261 tcattgctat gccgtttgac agcagcagag atttttgcca tctgcattag agaaaagatt
    19321 ccttcttgca tccgtgcgcc acctgaagct gtgaacaaga cgactggaag actttccttt
    19381 gttgctcgtt cgaataatct ggtgatcttt tctccgacaa tcgttcccat acttcccatg
    19441 ataaaattag gatccatcac tccaataatg aagggaatcc cctgaatggt tgctttacca
    19501 gtgaggactg cttcatgaag tcctgtttta tcttgcattt ttttaatttt ttccgtatat
    19561 tcgggaaatg ctagcggatc tttggttaca agatccgtat cccattcttc aaaacttttt
    19621 tcatcaataa tcaaagctag acgctgccat gcaccgattc gaaaagcgta tccgcaatga
    19681 gggcatactt tttcttcacc gatgtctttc gtataaagga tatgtttgca atttggacac
    19741 tttgcccaca tgttatcagg aacagatggc gagttagcag gtttgctctc tctattagga
    19801 ttgatccgaa tatatttctt tttcttaaac agagccatct atgcgcctcc tatctccgtt
    19861 tctggtgtcc aattcggtaa aaattcttct tgtaaaaatg ctgtgctgta atcacctgct
    19921 atgactgcag gatgactaat caaatccatc tgaaattctg cgttcgtgat gattccttct
    19981 gtgataaatt cacttaaggc tcgctgcatc ttcattaatg cttcaaaacg cgtatttcca
    20041 tggacgatta tttttgcaat cattgaatca taatatggcg ggatcgtata tcccgggtaa
    20101 actgcactgt ctactcgcag tcccatccca cctgctggaa gcagtaagtt ttggatcttc
    20161 cctggagaag gagcaaaatg gaaagcagga ttttctgcat taatccggca ttcgattgcg
    20221 tgtccttgga atactacttc ttcttgacac acattcaaag gctcaccggc tgctatctcc
    20281 acctgttttt ttactaaatc gattcctgtg accatttctg ttactggatg ttccacttgg
    20341 attcgagtat tcatttccat gaaataaaaa tcgccttctt catccatcag aaactcgatc
    20401 gttccggcat tttcataatt gactgcttta gctgctcgaa cagcagcgtc tcctagtgct
    20461 tctctttttg tttgtgagat cactacagaa ggagattctt ccagtacttt ttgattgttg
    20521 cgttgtaaag aacaatctcg ctcgcctaaa tgaatgacat gaccaaatcg atcacctaag
    20581 atctgaactt ctatatggcg agcaggataa atgatttttt ccaaatacat atcatcattt
    20641 ccaaatgccg ctgctgcttc ttgctgagct gaagaaaaat gctgtgggag ctcttctttt
    20701 gattgaactt tccgaatgcc tttcccgcca ccacctgcag ctgctttcag catcactgga
    20761 taaccaattc tgtctgctat ttccaatgct tcttctactg tagataatac accagtactt
    20821 cctggaatga ctgggacatt tgcttcttgc atcaattgac gcgcattgat cttatttccc
    20881 attgcatcga tcgttgcact tttaggacca ataaatgtga tattgcactc ttcacacatg
    20941 gaggcaaatc ggctattttc agataaaaaa ccaaatcctg gatgaattgc ttcggctttt
    21001 gtcacgattg cagcgctcag tacttcctga acattcagat atgaatcaac ggcttttgcc
    21061 gggccaatgc agattgcttc atctgctaac tgtgtatgaa gtgcttcggc atctgcttct
    21121 gaatatatcg ctacggtttg gatccctagt tcgcggcatg cacgaatgat acgtacagcg
    21181 atttcaccgc ggttagctat caatacttta gaaaacatat ttcacctatc caatcataaa
    21241 ggttaattcc gcttcggcta cttttttacc gtctacttta gcgattcctt tgcctattcc
    21301 ggctgaagct ttcactttca atatctcaac ttcaaggtat aaggtatctc ccggtgtaac
    21361 tttcttacgg aattttgctt tgtccaatcc gccgaaataa gccgtctttc ccttgaattg
    21421 ttcaagagaa agtaatgcaa ctgctcctgc ttgagccatt gcttcaacaa tcaatacccc
    21481 tggcataaca ggttcttctg gaaaatgtcc ttgaaaaaag ggctcattga tcgttacatt
    21541 tttcttagca acgatccgtt ctccttcaac catttcttcc actcgatcaa tcaaaagcat
    21601 tggataacga tgtggaatga tttcttttat ttcttgtatg ttcattgttt tccctctttc
    21661 ctgctttgct tatttttgct gaatcctaaa gagtggctgt ccatattcga caactgactc
    21721 gttttctaca aggatttctg tgatcactcc gtcggcctca ctagttatct cattcatcag
    21781 tttcatcgct tcaataatgc agataacttc tcctttggca acttgatcac ctactttttt
    21841 gaaagctggt ttgtcgggcg ctggttgcag ataaacgatt cccacgattg gcgaaacaac
    21901 ctcgattcca tcaaatactg ccgattcttt ttctttcatt atttctggag cagttgttgc
    21961 ttgttcaggt atgacattga ctggctccga aactggcaac gtttcgtttg tttgaaccat
    22021 attcatgcct cgacttgttt tatttttatt catatacaat tcaaattgac cttcacgcaa
    22081 atcgaattcc gttagcgagg attgatcaaa ttgactgact aattctctga tttcattgat
    22141 atccaaaatt attcctccca gcgtttcatg cacagaaccg cattatgtcc gccaaaccct
    22201 aatgaattac tcattgcata agtaaaactt gcaggtttgc tttcgttttt gacaactgtc
    22261 aagtcaatct caggatcttg tttttctaca ttgatcgtag gtgggataaa ttgatgttct
    22321 aatgccagca aagttgccaa ggcttcgatc ccgccggctg ctcccaataa atgtccagtc
    22381 atcgatttcg tgctgctgac gtaagtatct ctgaaatttt cacctaatgc gatttggatt
    22441 gcttttgctt ctgcctggtc attggctggt gtacttgttc cgtgagcatt gatatatccg
    22501 acttgttccg gctgtacacc agcttcttcc atcgcaagct tcattgcttt agatgcacca
    22561 gaaccatctg gagtaggagc tgtcatatgg taagcgtcac agtttgcacc gtatccaacg
    22621 atttctccat agattttggc accgcgagct tgtgcatgtt ctaaagattc aagaactaga
    22681 acgcctgctc cttcacccat cacaaaacca ttccgatttt cgtcaaacgg aatcgaacca
    22741 cgattaggat cagttgattc tgagagtgct gttaaagctg caaatccagc aatccccatc
    22801 tcacaaatcg ttgcttctgt tcctccagca agaatgacat cagaatagcc atgtttgatg
    22861 ttacggaatg cttccccaat tgaattcgtt ccgctagcac aagctgttac gatagctgta
    22921 caaatacctt ttgcacctac acgcaaagca atatttccag ctgccatgtt ggcaatcgcc
    22981 attggtacga acattggaga aactcgtttt gcaccttttt catgtagacg aataacttgg
    23041 ttttcgattg ttggaagacc accgatccca gatccgatga tgacgccaaa ccggtcttga
    23101 ttcatttttt ctttatctaa accgctcatc tccattgctt ctaaagcagc gtagattcca
    23161 tagatcgaaa acatatccat tcgtttgcta tcttttttaa taaaatattt atcgtaaggg
    23221 aaatctttga cttcacccgc taaggtaatc cctgtttctg aagcatcaaa tttagtgatc
    23281 ggtgcgatgc cattcgtccc ctcttttaag ctattcaaaa agctgtctgc gtcatttcca
    23341 ataggtgaag tgactccata gccagtaatt accactcgat tcatttgttt gctctccttt
    23401 tcttatccgt gcatgaccaa tccgccatcg acattgatga cttgtccggt gatatatgga
    23461 ttttgtgcta agaaaactgc tgtttgtgca atatcttcta cttgtccgaa acgctgcatc
    23521 ggaatttgct tttccgcttg ttccttgact ttgtctgcta aaacttccgt catatcagtt
    23581 gtgatgaatc ctggcgcaat ggcattacat gtaatgcctc tagttgcagc ttctcgtgcc
    23641 acagattttg ttaatcctac tacgccagct ttactagctg cataatttgc ttgaccaata
    23701 tttccaatca acccagatac actagagaga ttaatgatgg ccccttctcg ctgcttcatc
    23761 atttttttca atacgtgctg cgtcatattg aaggttccaa tcaaattgat atccagacat
    23821 tttttgaaat cttctgcatc cattcgcatc acaagtttgt catttgtgat tccggcattg
    23881 tttactaaca catggatcga tccaagcttt tcttctgctt ctttgatcat ttgtcccgct
    23941 ttctcataat cagagatgtc accggaaact cctacgcatt ttacaccgaa tgcttcgatt
    24001 tcttctatct tttcttttgg aatctctccg cgaccattca aaatgatatt tgctccagct
    24061 tttgcaaaag ctaaggccat cgctttgccg attcctcttg tactacctgt gataaataca
    24121 ttttttcctt ttacatccat aacgttcctc cttatagtat tgctattgtt tcatcaaatg
    24181 tctgcttatt ctcaacacgc agaactggta ttgttttatc gatttttttc ataaatccgc
    24241 ttaatacttt tccggggccg acttcgatga cttgttcgat gccgattgtt tttaacttat
    24301 ggatactctc atagaaacga acaggttgca tgacttgctg ttcaagtagt cccgcgattg
    24361 tttctttctt cattatttcc gttgttgtgt tgcttatgat aggaaaagaa ggttcagaga
    24421 attgaatctg acttaggtcc ttcgccagtt tttttgctgc cggttctaaa atagctgtat
    24481 gaaaaggccc gctgacattt agagggatca ttcttttgaa ccctttttct tttaatagta
    24541 aaacagcttc gtctactgct ttttcttcgc caccaatcac gatctgctga ggtgtattat
    24601 aatttgcagg agatacgatg ccgtacttgc tagcttcatg acagctttcc tcgatcgttt
    24661 caatcggcgc attcatcact gcaaccattt tcccgcttcc agctggggca gcttctgtca
    24721 tataagcgcc tctttttgct actaacgcaa ctgcttcagt gaaggatagc gcattactag
    24781 ctactaatgc cgaatattct cctaaactca gtcctaaagc tgcatctggg atgattccat
    24841 gctccttcaa taagcgataa tacgcgatgc tgactgttag aatagctggc tgtgtatatt
    24901 gcgtctgatc caaacgttca ttttctgtaa agcaaagttc agccatatcg tagccgagaa
    24961 tctcacttgc ttcatcaaat gtctgcttta caacggcttc ttcatataaa tcttttccca
    25021 taccttgata ttgtgcacct tggccactaa ataagaatgc tgttttcatg tttttctcca
    25081 atatatccag aatatatgtt tgattcttcc tattcaaaaa ggccgagaca ttcctatttc
    25141 aggaaatgtc ccagccccca acctaatttt aatgattatg cagtttgttt ttctacgtaa
    25201 gtcactaaat cttgaaccgt tttgattccg tcttctgttt cgattttcac gtcaaattca
    25261 tcttcaattt cattgatgat ttggaataaa tccaagctgt cagcttctaa gtcttcttgg
    25321 atgtcagtag tcaatttgat ttcttcagtt tcttttccta attcttctgc gatgatttct
    25381 tgaatttttt cgaataccat aataatatat tcctccgata ttgtttgctt tttattttta
    25441 taatttaaca gtctacaact ccatgagaat acttccccat gttaaacctc cgccatagcc
    25501 tgtaaatatt actttctgct gttttcctaa ggtgatcttt ccactagaaa ctgcttcatc
    25561 caataagata gggatgcttg cagcagatgt attcccatat ttatccatat tggtcaggaa
    25621 cttttcttgc ggcatcttta cttttcgggc aattttctca ataattctga ggtttgcctg
    25681 atgcaaaagc agataatcaa ctggtttgtc tttcatgact tcttggatat tgtttgcaac
    25741 gtctcgtacg gcaaaatcaa aaatatctct gccagtcatt tgcaaataat acgaaccttc
    25801 tgaatcttct gaatagaacg gatttttatt ttgctggtag ccagcggtca atgagctact
    25861 tctggtaccg tcagctgcta atttttcttt cagcaatttt ttctgtggat tcgcttctaa
    25921 gagaatccca cctgctccat cgccaaacaa cacagcagtc gtacgatcag accaatcgat
    25981 tagcttagat agtgtttcac caccaatcac cagtccctta gttgagccgc agcggatcat
    26041 tttttcagcc atgcttaacg cataaacaaa tcctgagcac gcagcactga tatcaaaagc
    26101 gatagcatga gttgctccca atttcccttg tacttgtgct gctacagatg gtgtcgtgta
    26161 atcgggcgac attgttgcta ctaaaataaa atccaaatct ttagggttta gatttttctg
    26221 ttttatcaat ttttccgcca ctaaaatgca taaatcagaa gtctcctgat ttgttacaca
    26281 tcttcgttca cgaatacccg tccttgacga aatccattca tcagaggtat ccatcatctt
    26341 ggaaagatca ttattagtaa taatcttttc aggaaggacg ctggctgttg cagtaatcat
    26401 tccaaattgt tccattaaat atcctcactt atagtcttgc aagaagtcgt gcaagttttt
    26461 cagtgcatcc agcaaggcat gctgttcctc cgtagccatt ccgtctaaga tgttcttgac
    26521 catttcacga tgaaaatgct gatggacccg aaatagtaac tttccttttt tcgttagtcc
    26581 caactttaca acgcggcggt catcttcact gcggatacgt tcgacatagc ctttttttac
    26641 taacttgtta atagcagtgg tcaaggtccc aacagtaatt gatagttctt tggctacttc
    26701 tgaagttgtt tttttcttgt acatcccgat tgcctcgatc gtgtgcatct ctgtgattga
    26761 cagatctttg aattgagatt ttttcagctc agactcttcg attgtcaaaa tatcattgaa
    26821 gacactaaca agataatcat ttactgtttt taaatctggt tccatgttcc accgtccact
    26881 aattagtttg attatcaaat cttttgatgt tcaaactata tcttaacttt tttcaaaatg
    26941 caaccttaaa agatcatttt tttactatat gagctttttt taagatttta ctcatttaaa
    27001 acaactgata aatcagcatt tataatttct tttattagaa aaatcatcta tctcacatat
    27061 tttgattatc aaagtatttt ctgtgaacag aactatagaa ttccctaaaa cttgtccatt
    27121 atttcaaaat ttgttatagt ctttttattc aaagcgtaaa aggagatcct atgttaaaag
    27181 aaaaaatgaa aactctcccc atgctgccgg gtgtctatct tatgaaagac cgagatggta
    27241 aggtcatcta tgttggtaaa gcaaaacggc tcaaaaatag agtaagcagc tattttcatc
    27301 agaataaaca gcattcaaaa aaagtattac gtatgattca tcatataaca gattttgatt
    27361 tcgtcgtagt agacacggaa ttagatgctt tattgctcga gtgtcaattg atccaacatt
    27421 accgtccttt ttataaccga caaatgaatt atttcagtaa ttataattat gtacatatta
    27481 ccaataaggg atttgtatta acagatactc ctacggctcg aacatacggg ccttttcgtc
    27541 tctataaaaa aatgccgtct attttgcgta taatggaaga aacttatcaa atgccttggt
    27601 tgtctgaaat tagtttgtta gctttgcgag tccagcttcc tgacctacag gaaatgactt
    27661 ttgaacagaa aaaaaaggaa ctccaagggc tgtttcaagg ccgaaataaa aagctactga
    27721 cttacttgaa aaaaagacaa caacatttca tctatcagtt gaatttcgaa aaagccggta
    27781 tgcttcaaaa agatatcgaa ttagttactt attttattag acggatccag gaacaaaagc
    27841 agtttttaag aacaccatcg ctcaccttca gcatgccatt agcagcagat gagagtcaga
    27901 aaaagcacta cctcgtttgt tatggtcaac ttgcagaaac aatgattacc tctggtgacg
    27961 tttctcctga cttctattat gaaaagaaag aagctcattt atctttgaaa cgtcaattgt
    28021 caaaagaaga aatcgatcct gtacaaatct tgatcagtta ccgcaaaaaa ttagaaaaag
    28081 aacagtttga aattgaactg ttaaacaaaa aagaagctga aaagcaacta aattagttgc
    28141 ttctcggctt cttttaggca tcttcaactt caaatgtcaa ttatcctaaa atttattgga
    28201 ttaagtcata gatttccatc gctacgatat cgatattatc aaattcgtat tgctgatgag
    28261 tatctgtttc agttaattca aatgtatcgg tcgctttatc ataagttact gtacacttct
    28321 ctacgccttc tttttcaaaa cggcgaactt gcagttcatt atctgctgac tcgaccatag
    28381 cctccagtcg ttttatgatt gcgactaatt gtgaatgtgt catcggaggt cctccttttc
    28441 ttatttctgt tatattgtat caaaagcata gcctacttgc attgattttc tctaaaaaaa
    28501 ctcgtttttt atgatttttt ttctggtatt tttccttcag gccaccaaag tttgatcaaa
    28561 gcttgggttc cgtcattctc aaaaccttta tctgccaact cttcatatag tttcaatgct
    28621 tgggtagttg ctggcaatac aagatccatt ttttctgctt cttctaatgc aatctttaaa
    28681 tctttgataa aatgtttgac aaaaaaacca ggtgtgtaat cttcttttaa aatacgagga
    28741 gaataattgc ttaaagacca gttagctgca cttccacctg aaagcgtctc aatcactttc
    28801 tttaaatcaa gtccgttttt ttgtgcatag acaagcattt ccgtcattcc tgtcatcgta
    28861 cctgcaatca tgatctgatt agccattttt gtatgctgac ctttcccagc agaaccatgc
    28921 aatgtaaatg tcgtaccaaa ttctttgaat aaaggcagta cttgatcata aacggcttct
    28981 tctccaccga ccatgatcgt cagtgtacca ttctttgctc ctaagtcacc accggatacc
    29041 ggtgcatcta acgcatctgc gcctttttct tttgctgttt ttgcaatttt ttctgccagg
    29101 ctggtgtact tgtagtcaaa tcaactaaaa tatgtcctga gatatctgca gaaaaaatcc
    29161 ccgactgtcc atagtagatt tcttctacat ctttggggta acctaccatt gtaaagagaa
    29221 tattactttg ttctgctacc gcttttggtg tatctgccca gatagctcct tctgttacta
    29281 aaggatcagc ttttgctttt gtccgattat agacagctac ttcgtgtcct gcttctagta
    29341 gatggcgtgc gacagcactt cccatgacgc ctgttccgat aaaaccaagt ttcatttttt
    29401 cgacctccta aaaatcaaaa atccttgctt ctatgctagt atacgctaga aacaaggatt
    29461 ttttcataaa aaatgtttga attttatctt ttaaatgaat ttaattttat tttgattcgt
    29521 tcaatcgagt cttcttcttc ttttcttcgc atctcttctt catgataaac aaccatgtct
    29581 tgataaaatt cgatcatagc ttcgccgaaa tgtgtagatg aaatatcata aagtttagct
    29641 tctaaaactt ttggatcttt aggaacttca ctggaaatat aatcaataag tgctggtgca
    29701 aagtcttcgt cggtttcaaa agttttccct aatgaaggat gatcgaacaa tcggttcaaa
    29761 taagcatttc cttccacgac acaaggtgtt ccggctgcca tcgcttctgt ataagtaagc
    29821 ccttgtgttt ctgaagtaga agcactgaca aaataatctg ccgctttata ataaagtgct
    29881 acatcattgt tgtccacttc tcctgtgaac tgcacaaatt cttctaactg cagttctgag
    29941 atcaattcct ctaactcttc tacataaggt ccttttccta cgataactaa tctggcgtta
    30001 ggataagcgg agatgacctg aggaaaccca ttaatcaagg cttggatatt tttctcataa
    30061 gaaatcctgc ttaaagaaag aatcatcaaa tggttttcct gaagacctag tgactccctt
    30121 aatttgctga tatcctgctg agtgatatca gaacgtttga atttttcaat gtcgatacca
    30181 gtaggaatca cgcgaagcgg tgctattaca ccatagctgc gtaatgtatc aataacacgt
    30241 tcacttggac aaactacacc tgtcgtatga tttgcaaata atctagacaa gtattttaca
    30301 tgggattgcc tgatcacttt tcctttaccg atataatgaa ggtagtcttc atacatcgta
    30361 tggtaagtat ggatcagagg tattttcaac ttcttagcta ccatcttccc aagtatccct
    30421 gctccgaatt ctgtatgggt atgaataaga tctagttcta gttctttggc aaccaaataa
    30481 gcataccaca tgcctctaac aacaactctt cgatccttga aagaaataaa tggtacactt
    30541 ggcattcgaa tcacatcttt ttccaactta tccgcattag gatcggtcgt tgtaaaaata
    30601 tagacttcat gcccatgtct ttctaattct tgttttaatg ttttgatcga tgtagcaact
    30661 ccgctgactt gcggaaagta ggtatcggta aaaaagccga ttttcatgtt tttcgcctcc
    30721 aaactagtcc ttgacctgat ttactttttt taatttgcta gagacttttt cattcagtac
    30781 actttcgtat acatttttaa gttcttcacc gattttattg atacttcgct cttttgctgt
    30841 ttgataaccg gcttgtgtcg tactcggtag ttcttgattg gtaatctgtt ggatcagtcg
    30901 gataaattct tcgtttgtct tccccatata gcagttcttg ctatcttcta accagccatt
    30961 atacactgga atatctcgaa caagtacgtt ttgtttgctt gctaaagctt ctaaaacaac
    31021 gatcccttct gtctcttcat aagaagggaa aaagaataga tctgcacctg aatacgcacc
    31081 ttctatgatc tctccacgaa tgtaaccagg aaacaggaca ttttcaggat gatcttcttt
    31141 tacaattttc cggatgttcc gaggaatcga gtacatggga acatgaccaa accaaataaa
    31201 tgtgtattcg ggcatcttct tagcaatttc tacgaaatca atgattcctt tacgttcgaa
    31261 aaacaaaccg acacaaatga ttactttttg atccggagac agtttgaaat attctctgaa
    31321 cttttgttct ttcattggat cagggtgata tttctctaag tcgatcccat tggaaatagc
    31381 ttgaatcggc acacggatac catagctttc caacaactgt tttgaataag gtgttggcgt
    31441 gatcagatag tccgcttttt ggtacaatcc taccagatat ttttttacga taggagaaag
    31501 ctggttcgat ctgataaagg aatttcggaa atcttcctct gtagaatgcg catgatagac
    31561 aacttttttt ccttctcttc tggctttatt gaccatatta tgactattga ttccgtatgt
    31621 attgatgtgc aggatgtcat aatcttcttt ttcatctagt gtataagaga taccgacttc
    31681 cgtcagagca cgtttttgat gatcaagcgc acgcccgatt ccagattttg caagcatctt
    31741 ttcactttca aaatataata ataccttcac cttacgtccc ccttcactta tatagtataa
    31801 catagcctac aaactgtcac tcaaacttaa gccctatttt tgtctattct tactgacaaa
    31861 aacgttttct taaaaaagaa caaaaaaact ggcgtagctc ttttacaagc cacaccagct
    31921 tttgatacgt tgtttatttt acatattcat gaacaagttc aacgacttct tccatcatat
    31981 cgcattcttt caatgcacga tcagcaagtt cagccatttt cgctgtgtcc aagcgtttca
    32041 ttaaactacg cgttttaaga atagatgtcg cactcattga gaactcatct agacccatac
    32101 ctactagcaa tggaacagct gtttgatctc cagccatttc tccacacata cctgcccatt
    32161 ttccttcagc gtgtgctgca tcaattacat ttttgatcaa acgtaaaatt gatgggttat
    32221 atggttggta caagtaagaa acgcgttcgt tcatacggtc tgctgccatt gtgtattgaa
    32281 tcaaatcgtt cgtacctaca gagaagaaat ctacttcttt tgcaaacttg tctgctaaga
    32341 ctgctgctgc tggaatctcg atcatgatgc cgacttggat cgtatcagat acttccttgc
    32401 cttcacttat caatttttgt ttttcttctt caaagatcgc ttttgctgcg cggaattctt
    32461 tgagtgtagc taccataggg aacatgatac gtaaattacc atgaacagat gcacgaagca
    32521 atgcacgcat ttgtgtacgg aacatttcgt cgccttgttc agataaactg atacgcaatg
    32581 cacgatatcc taagaatgga ttcatttcat gaggtaattg cagatatggt agttctttat
    32641 ctccaccgat gtccattgta cgaacaacta caggttttcc ttccatacct tctaatacag
    32701 ctttgtaagc ttcatattgg tcatcttctg ttgggaagtc tggagaatcc atatacagga
    32761 attcagtacg gtacagacca actgcttctc caccattatt atggacacca actagatctt
    32821 ttggtgttcc gatgtttgca gctaattcaa aatgcttgcc gtcagctgtg acagtttctg
    32881 cattttttaa tttttcccat tctgcttttt gtgctgcgta atctgcacct gctttttcaa
    32941 attcagcttt ttgttcatct gtaggatcga tgattacatc gccttcgatc ccgttgacag
    33001 ccaaaatatc gccttctttg actttagcag taatttcttt tgtcccaacg attgctggaa
    33061 tttctaaaga acgtgccatg atagcagaat gtgaagtacg tccaccaatg tctgttacaa
    33121 acgcttttac aaaattgcga tctaattgtg ctgtatcact tggagtcaag tcatgtgcaa
    33181 caacgaccac ttcttcgttg atcattgatg gatttggtaa agtaacgcct aataagtgcg
    33241 ctaaaatacg tttagcaacg tcacgaatat ctgcagcacg ctcttgcata taagcattat
    33301 cttccattgc ttcgaacata ccgatataca tatccgttac ttcttttagc gctgattcag
    33361 catttacgct gttgtcttta atattttgct tgatttgacc taccatttct ggatctgaaa
    33421 gaaccatcaa atgggcatca aatacttgcg cttctgcttc acctaagctt tgcgctgctt
    33481 tttcacgaat ttgctgcaat tcttcagtag atttagctaa tgcagcatcc aaacgagctt
    33541 cttcagccgc agtatcttct actgttgcct tactgaatgt taaatccggt tgaactagca
    33601 ggtaagcttt tgcaacggct acaccgtcac tagcggcaat cccttttagc atttcaacca
    33661 ttattcagat aagccttctt tcttcattgt ttcaacgatt gctgccattg catcagcttc
    33721 gtcagcacct tctgcagtaa tagtaacatc agaaccttga cctacaccta aagacataac
    33781 gcccatgatt gatttcaagt ttactgattt acctttatac tctaagttta catcagagtt
    33841 aaatttgctt gctgtttgta ctaatagtgt agctggacga gcgtggatcc cagtttctgc
    33901 tactacgtga aattctttct tttccatatt aatcggtctc ctttaagtga gtgttgtttt
    33961 tatgtgaggg ttttcttttt tagtaattca gagaatccta acaaatgcca ccctttcatc
    34021 tgtaaagatt aacatttttt ttcgttagat acaacagttt tcattcaatt tcagataaaa
    34081 gtattcaaat tattccggat tctttttcat ccttttcttc acattttata acaaacgtgt
    34141 ttatttcctt tttcttgtcg ctttctcttc tcctgacgtt tatcattctt tcctttgacc
    34201 ctctttgttt tcatatgaaa cgaattactt gcttcccttt ttatttttag tataataaga
    34261 gtcaaaggtc aggaatggtc aatagagatt tcaccttttc tacctcataa atctcttaaa
    34321 aaactagggg ttattctttt acctcatgaa aaacgagatg taaaatatgg atgtacccat
    34381 ttttgtgaaa ggacgtgaat gattcatgct ttgtcaaaac tgcggcaaga atgaggcaac
    34441 gattcacttg tatgccactg tcaatggtca gcggacacaa ctcgattact gtcagagctg
    34501 ttatcaaaaa atcaaaaatc aacaaaatgg aggtctgact aatatggccc aaaatgatcc
    34561 atttggattt ggcagtttgg acgatctttt ccgttccatg tctcgccaaa tgcaacagca
    34621 aggaaattat gagcaaacac caccaacaca atttggcgga aacaacaact tcaatggtgg
    34681 tcagccacct caaggcaata cagaaggttt attgggagaa tacggaatca atatcacaga
    34741 acaagcacga caaggtgata tcgatcctgt gatcggacgc gatgacgaaa tcaaacgagt
    34801 cattgaaatt ttaaatcgcc gaaccaagaa caatcctgtc ttgattggag aaccaggtgt
    34861 tggtaaaaca gcagttgttg aaggtttagc acaaaaaatc gtagatggtg atgtaccgca
    34921 aaaattaatg gacaaagaag tcattcgttt agatgtcgta tctttagtcc aaggtactgg
    34981 tatacgagga caatttgaag aacgtatgca aaaattgatt gaagagatcc gtcaagcaga
    35041 aaatgtgatc ctattcatag atgaagttca cgaaatcgtc ggtgctggtt ctgctggtga
    35101 tggaaatatg gatgctggta atattttaaa accagcttta gctcgaggag aattgcaaat
    35161 ggttggtgct actaccttaa atgagtaccg catcatcgaa aaagacgctg ctttagaacg
    35221 tcgtatgcaa cctgtacggg tagatgaacc aactgtcgaa gaaacgatca gtattttgaa
    35281 aggtttgcaa aaacgttatg aagactatca tcatgtaaaa tatactgatg aggccatcga
    35341 agcagccgca actttatcca atcgttacgt ccaagatcgc ttcttgccgg ataaagccat
    35401 cgatttgcta gatgaaacag gttctaagaa aaacttgacg atccaaatcg ttgatcctaa
    35461 aacaatcgag aaaaaactgc aagaagcaga agaacaaaaa gttttagctt ctcgagaaga
    35521 agatttcgaa aaagcagctt attatcgcga tcagatcaat aaacttcaaa aaatgaaaga
    35581 acgtcagctc actgaagagg aaacacctgt gattaccgaa aaagatatgg aaaaaatcgt
    35641 tgaacaacgg acaggtattc cagtgggtga attaaaagaa aaagaacaga cacaactgaa
    35701 aaacttagca gatgacttga aagctcatgt catcggacaa gataacgctg tagatcgagt
    35761 agcgaaagcg attcgccgaa accgtgttgg attaaacaaa cagaatcgtc caatcggctc
    35821 cttcttattt gttggaccaa ctggtgtagg taaaacagag cttgcgaaac aacttgccta
    35881 cgaactattc ggttcacaag attcaatgat tcgtttcgat atgtctgaat atatggaaaa
    35941 acatagtgtc tctaaattga ttggttctcc tccaggttat gtcggatacg aagaagctgg
    36001 tcaattaaca gaaaaagtac ggagaaatcc ttacagtctt gtcttgttag atgaagtaga
    36061 aaaagctcat ccagatgttt tgcatatgtt cttgcaaatc ttagatgatg gtcgattgac
    36121 agatgcacaa ggaagaacgg tcagctttaa agatacgatc atcattatga caagtaatgc
    36181 cggaactggt aaagtagaag caaacgttgg ttttggtgcg gcacgcgaag gtgttactcg
    36241 ttctgtattg aaccaattaa acaactactt tacaccagaa tttctgaacc gttttgacgg
    36301 gatcatcgaa ttcagtgcat tatcaaaaga aaacttgatg acaatcgtca cactaatgct
    36361 agacgatgtc aaccaaatgc tggcagcaca gcaacttcac atcgaagttc ctacgaatgt
    36421 caaagaaaaa ttagttgact taggctatga tccatctatg ggtgctcgtc ctcttcgacg
    36481 cacgatccaa gaacaaatcg aagatggtat cgctgaattt tatcttgatc acccttctat
    36541 ccatgagttg aaagcaaaac tggataaaga tggaaaaatc atcgttactt ctaaaccaga
    36601 acgtttggct aaagaatcag ccgaagaaac ggctgaataa atccagtttt atagcgtgag
    36661 acggtatttc tttgagaaat gccgtctcat tcttttttca gaaaagtcaa aatactgttc
    36721 attttataaa aaagaaatta taataagaga aacaagcaat taaaaataca taaaagaggt
    36781 gagcgccatg aaattggtaa atgtaacaaa cagccattcc cgtcttgtat taaaccagct
    36841 tgaaaacact gatgcccatc tagtcaaggt ctacacagcc ggaaatacca ctattgtcta
    36901 cactgaagcc cctgaacata atgaaattct gctgatcaat gacaaacgta aaatccagcc
    36961 gaaagaaatc gaagatgcta aaaattattt cttagataaa atcaaagacg ccgtttacca
    37021 cgaggatgaa atcaaagtaa tcgaattggc aggccttgtt gaaatctcga ttccaaaaca
    37081 tgaattaggc gctacattag ccgtgtaaac aaattttgaa cataataatt aaagagcgtg
    37141 ggacaaaagt aaagaacact tttgtctcac gctctaaaca cgtataaacg gcgaaagcag
    37201 aagcaactcc ttcggaaata agctgaaatt cacgaaaatt gcttttcaaa tttttgtgaa
    37261 ttccagctta tttcttggag ttaaacgctt ctgtctcagc ctctttttct ttctagcttt
    37321 ttgatttttc tcttttcttt tgtacttttc tcttttcatt ttcagttcta cgcgtgtctt
    37381 tatttttaac tttttcctct ttatggatga ttgatcgtac tttttgtgca atttgctcgt
    37441 ttttgtccca gtcttttaca tctaataatc gacataatcg taacatctct tcttttttct
    37501 gtttttttct ttcacgtctt tgccattctg tttccatgtg tcacactctc ctttctttaa
    37561 tcatatgtac gcaaaataat ttttatattt ttttgattag acatttctat gattttaata
    37621 tagtaaaaag agccgtcacg gaaaatccgt cacggctcta aacaaaatat gagaggctgt
    37681 ttttgtttgg ctattcttat tacttgatgc agggcagctt gtgtcaagac ttctttacat
    37741 caaacttttt aattttacat tgggatattt atccgcaaac cagcgttctg caaattggtt
    37801 ctcgaataag aacaacggtt ggtcgaaacg gtcacgagcc aagatattgc gacttgaact
    37861 catcttctca tccaaatctt ctggatcgat ccagcgagcg attttgtgtc ccattggaga
    37921 catgattact tcggcgttat actcatttaa catacgatat tggaatactt cgaattgtag
    37981 ctgaccaaca gctccaatga tatattcttc cgttagatat gttttataaa gctgaatcgc
    38041 tccttcttga actaattgat agattccttt gtggaaggat ttttgtttca tgacattttt
    38101 tgcagtcact ttcataaaca gctctggagt aaatgaaggg agttcttcat aagcaacttt
    38161 tagttttcct tcgaacaatg tatccccaat ctgataattg cctgtatcat atacaccgat
    38221 gatatcgcct gctactgctt tttcgacgtt ttctctcgaa tctgccataa attgtgtgac
    38281 attgcttaat ttcagttttt tatttgtacg ttccaaccag acatccattc ctcgttcgaa
    38341 tgttccagaa cagattcgga caaaagcgat tcggtcacga tgggctggat tcatatttgc
    38401 ttggatcttg aatacgaaac ctgaaaattc ttcctcataa ggacttacca tctgatcatc
    38461 ttgtgttttg tgtccataag gagctggtgc caattcaacg aaagtctcta aaaaagtctg
    38521 tacaccgaag ttagtcaatg cagaaccaaa aaatactggt gtctgatcgc cacgagcaat
    38581 tttttcttga ttaaatgcat ctccagcctc tttgattagt tctacttctt ctaagacttg
    38641 ttcatataag gaattttcag ttagaggatg attttcggga agcagtccat cttcatccaa
    38701 ttctactaat cgttcatcct gataattttc cggacgataa aactctacac gattatggta
    38761 gatatcataa agaccttcta gccctttacc cataccgatt ggccaattca tcggataaga
    38821 ttcgatatct aatagctctt ctaattcttc taacaattcc aatggttcac gaccatcacg
    38881 atctagtttg ttgataaaag taaatatcgg gatgccacgt ttttttacaa cttggaataa
    38941 tttctttgtc tgtgcttcga tcccttttgc actatcgatt accatgaccg cactatccac
    39001 ggccatcaaa gtacgataag tatcttcaga aaaatcttca tgtcctggtg tatccaagat
    39061 atttactcgt ttcccttgat aatcaaactg cataacagaa ctagtaacag aaatcccacg
    39121 ttgtttctcg atttccatcc agtctgattt ggcaaaatta cctgtttttt tgccttttac
    39181 ggtcccggct tgacggatag ccccaccaaa caatagtaat tgttctgtaa tcgttgtttt
    39241 cccagcatcc ggatgggaaa tgatcgcaaa agttctgcga ttgtccactt gttgctttaa
    39301 ttttggatta ttcataacct aactccattt cttccattca attatttata ttttctctag
    39361 gcacagattg tccgatctct taaagaaaga caatttcata tagggctgtg acaaaagccg
    39421 tgtagcagtc tctttttccg agtaaacggc gttctagaga cagcctatca gcaataagcc
    39481 cacccaagcc aaaaatacga aaagctgttt ttgcttggct gctcttatta cttaatgcag
    39541 gatagctttt tcacaacctt tgtcaactac tacaactgaa tcagtatagc atggattcag
    39601 cgaatgaaaa agccaccaaa ccataagagt caaatatttt tttgtcagct gactaaaaga
    39661 aaagacgtgt tgcttgttta
//
LOCUS       DBBGSZ010000022        38249 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.022, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000022 DBBGSZ010000000
VERSION     DBBGSZ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 38249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38249
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.022"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            8..81
                     /locus_tag="ACIZE5_001583"
     tRNA            8..81
                     /locus_tag="ACIZE5_001583"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42..44,aa:Pro,seq:tgg)
     gene            101..173
                     /locus_tag="ACIZE5_001584"
     tRNA            101..173
                     /locus_tag="ACIZE5_001584"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:134..136,aa:Ala,seq:tgc)
     gene            201..274
                     /locus_tag="ACIZE5_001585"
     tRNA            201..274
                     /locus_tag="ACIZE5_001585"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:235..237,aa:Met,seq:cat)
     gene            288..361
                     /locus_tag="ACIZE5_001586"
     tRNA            288..361
                     /locus_tag="ACIZE5_001586"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:322..324,aa:Ile,seq:cat)
     gene            385..474
                     /locus_tag="ACIZE5_001587"
     tRNA            385..474
                     /locus_tag="ACIZE5_001587"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:421..423,aa:Ser,seq:tga)
     gene            487..560
                     /locus_tag="ACIZE5_001588"
     tRNA            487..560
                     /locus_tag="ACIZE5_001588"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:521..523,aa:Met,seq:cat)
     gene            579..654
                     /locus_tag="ACIZE5_001589"
     tRNA            579..654
                     /locus_tag="ACIZE5_001589"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:612..614,aa:Asp,seq:gtc)
     gene            656..726
                     /locus_tag="ACIZE5_001590"
     tRNA            656..726
                     /locus_tag="ACIZE5_001590"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:688..690,aa:Gly,seq:tcc)
     gene            740..813
                     /locus_tag="ACIZE5_001591"
     tRNA            740..813
                     /locus_tag="ACIZE5_001591"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:774..776,aa:Ile,seq:gat)
     gene            838..925
                     /locus_tag="ACIZE5_001592"
     tRNA            838..925
                     /locus_tag="ACIZE5_001592"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Ser,seq:gct)
     gene            947..1018
                     /locus_tag="ACIZE5_001593"
     tRNA            947..1018
                     /locus_tag="ACIZE5_001593"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:980..982,aa:Glu,seq:ttc)
     gene            1041..1130
                     /locus_tag="ACIZE5_001594"
     tRNA            1041..1130
                     /locus_tag="ACIZE5_001594"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1077..1079,aa:Ser,seq:tga)
     gene            1143..1216
                     /locus_tag="ACIZE5_001595"
     tRNA            1143..1216
                     /locus_tag="ACIZE5_001595"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1177..1179,aa:Met,seq:cat)
     gene            1235..1307
                     /locus_tag="ACIZE5_001596"
     tRNA            1235..1307
                     /locus_tag="ACIZE5_001596"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1268..1270,aa:Asp,seq:gtc)
     gene            1311..1383
                     /locus_tag="ACIZE5_001597"
     tRNA            1311..1383
                     /locus_tag="ACIZE5_001597"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1344..1346,aa:Phe,seq:gaa)
     gene            1388..1458
                     /locus_tag="ACIZE5_001598"
     tRNA            1388..1458
                     /locus_tag="ACIZE5_001598"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1420..1422,aa:Gly,seq:tcc)
     gene            1471..1544
                     /locus_tag="ACIZE5_001599"
     tRNA            1471..1544
                     /locus_tag="ACIZE5_001599"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1505..1507,aa:Ile,seq:gat)
     gene            1556..1627
                     /locus_tag="ACIZE5_001600"
     tRNA            1556..1627
                     /locus_tag="ACIZE5_001600"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1589..1591,aa:Glu,seq:ttc)
     regulatory      1816..1895
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SMK box riboswitch (SAM-III) riboswitch; SAM
                     riboswitches modulate the expression of downstream genes
                     in response to levels of S-adenosylmethionine; SMK box
                     riboswitch shares no known similarity to SAM-I and SAM-II;
                     Derived by automated computational analysis using gene
                     prediction method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            1893..3086
                     /gene="metK"
                     /locus_tag="ACIZE5_001601"
     CDS             1893..3086
                     /gene="metK"
                     /locus_tag="ACIZE5_001601"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HGC6108730.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3216..4688
                     /locus_tag="ACIZE5_001602"
     CDS             3216..4688
                     /locus_tag="ACIZE5_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HGC6108731.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            4771..5559
                     /locus_tag="ACIZE5_001603"
     CDS             4771..5559
                     /locus_tag="ACIZE5_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC6108732.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(5626..6294)
                     /locus_tag="ACIZE5_001604"
     CDS             complement(5626..6294)
                     /locus_tag="ACIZE5_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HGC6108733.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            6409..8121
                     /locus_tag="ACIZE5_001605"
     CDS             6409..8121
                     /locus_tag="ACIZE5_001605"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6108734.1"
                     /translation="MKLILRHAKKYKVSVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8124..9896
                     /locus_tag="ACIZE5_001606"
     CDS             8124..9896
                     /locus_tag="ACIZE5_001606"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6108735.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(9978..11099)
                     /locus_tag="ACIZE5_001607"
     CDS             complement(9978..11099)
                     /locus_tag="ACIZE5_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6108736.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQDMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNGVS
                     LARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELI
                     SLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKLIK
                     NNKDKYIFISKNGNPISIQAYNQSLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPL
                     KAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
     gene            complement(11171..12451)
                     /locus_tag="ACIZE5_001608"
     CDS             complement(11171..12451)
                     /locus_tag="ACIZE5_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HGC6108737.1"
                     /translation="MLLLIGLILLIIGITKLSKANTIKKEAYELEQKNDEKLNKLHDR
                     ERFILSKEETLSDLNKQITMLKNDIILLKKEKEDLNDEINQKYDETLKNVYSSLIVSN
                     IEETSSSEIKNKLSLLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            complement(12542..12994)
                     /locus_tag="ACIZE5_001609"
     CDS             complement(12542..12994)
                     /locus_tag="ACIZE5_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGC6108738.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(13007..13417)
                     /locus_tag="ACIZE5_001610"
     CDS             complement(13007..13417)
                     /locus_tag="ACIZE5_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6108739.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            13692..13904
                     /locus_tag="ACIZE5_001611"
     CDS             13692..13904
                     /locus_tag="ACIZE5_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiprotein-bridging factor 1 family protein"
                     /protein_id="HGC6108740.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            13907..14119
                     /locus_tag="ACIZE5_001612"
     CDS             13907..14119
                     /locus_tag="ACIZE5_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108741.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            14259..14414
                     /locus_tag="ACIZE5_001613"
     CDS             14259..14414
                     /locus_tag="ACIZE5_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108742.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGKKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(14411..14635)
                     /locus_tag="ACIZE5_001614"
     CDS             complement(14411..14635)
                     /locus_tag="ACIZE5_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HGC6108743.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            14713..14901
                     /locus_tag="ACIZE5_001615"
     CDS             14713..14901
                     /locus_tag="ACIZE5_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108744.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            14898..15071
                     /locus_tag="ACIZE5_001616"
     CDS             14898..15071
                     /locus_tag="ACIZE5_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108745.1"
                     /translation="MKKTDTLFIGFILGLLVIVAHQSIIGGSLFAALMVLINLLDSKE
                     RSNYGTRRSAKNR"
     gene            15040..15168
                     /locus_tag="ACIZE5_001617"
     CDS             15040..15168
                     /locus_tag="ACIZE5_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108746.1"
                     /translation="MAREEALKIGKVIADNRWGNSRPIILSKQHIEKQKAWQQIKK"
     gene            15227..15562
                     /locus_tag="ACIZE5_001618"
     CDS             15227..15562
                     /locus_tag="ACIZE5_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108747.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            15795..16736
                     /locus_tag="ACIZE5_001619"
     CDS             15795..16736
                     /locus_tag="ACIZE5_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lambda-exonuclease family protein"
                     /protein_id="HGC6108748.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            16738..17628
                     /locus_tag="ACIZE5_001620"
     CDS             16738..17628
                     /locus_tag="ACIZE5_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HGC6108749.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            17671..18471
                     /locus_tag="ACIZE5_001621"
     CDS             17671..18471
                     /locus_tag="ACIZE5_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HGC6108750.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADDIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            18486..19337
                     /locus_tag="ACIZE5_001622"
     CDS             18486..19337
                     /locus_tag="ACIZE5_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC6108751.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            19538..19999
                     /locus_tag="ACIZE5_001623"
     CDS             19538..19999
                     /locus_tag="ACIZE5_001623"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC6108752.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            20025..20477
                     /locus_tag="ACIZE5_001624"
     CDS             20025..20477
                     /locus_tag="ACIZE5_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108753.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            20583..20777
                     /locus_tag="ACIZE5_001625"
     CDS             20583..20777
                     /locus_tag="ACIZE5_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108754.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNEFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            20808..21101
                     /locus_tag="ACIZE5_001626"
     CDS             20808..21101
                     /locus_tag="ACIZE5_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108755.1"
                     /translation="MKLKDGFYSSGHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVVRLVDMEVIKS"
     gene            21032..21571
                     /locus_tag="ACIZE5_001627"
     CDS             21032..21571
                     /locus_tag="ACIZE5_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HGC6108756.1"
                     /translation="MVSEKQREFSSGEIGGHGSYKILILLFYNYPTTMSVIPQLEGEE
                     AIVNILENIDIKQTRKNARRLLKRYRNLERLVGPVKIDFSVMTVTKNLKFTIDSQNEE
                     IIEAISTRDSVIEALTRLSRIHFQVLYYSYCFPNKMSMYQIGEKLGYSDRTIERMKAV
                     ALVEFAEAYKSGELISRTK"
     gene            21646..22113
                     /locus_tag="ACIZE5_001628"
     CDS             21646..22113
                     /locus_tag="ACIZE5_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HGC6108757.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQHR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            22860..23090
                     /locus_tag="ACIZE5_001629"
     CDS             22860..23090
                     /locus_tag="ACIZE5_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108758.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMGREAE
                     PCEIDACKLVYCGHGFYDEPNIQNNINKNLRD"
     gene            23249..24082
                     /gene="terS"
                     /locus_tag="ACIZE5_001630"
     CDS             23249..24082
                     /gene="terS"
                     /locus_tag="ACIZE5_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit"
                     /protein_id="HGC6108759.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELISNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            24075..25490
                     /locus_tag="ACIZE5_001631"
     CDS             24075..25490
                     /locus_tag="ACIZE5_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGC6108760.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPESMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTKVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            25502..27031
                     /locus_tag="ACIZE5_001632"
     CDS             25502..27031
                     /locus_tag="ACIZE5_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HGC6108761.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKAPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            26949..28001
                     /locus_tag="ACIZE5_001633"
     CDS             26949..28001
                     /locus_tag="ACIZE5_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HGC6108762.1"
                     /translation="MTIETKYWTKRRELEDQARLKQENQTLKKLTSVFPEALKEIQAK
                     LLSQADLHNITYPEMMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            28003..28320
                     /locus_tag="ACIZE5_001634"
     CDS             28003..28320
                     /locus_tag="ACIZE5_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108763.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            28447..29070
                     /locus_tag="ACIZE5_001635"
     CDS             28447..29070
                     /locus_tag="ACIZE5_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HGC6108764.1"
                     /translation="MSMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            29085..29975
                     /locus_tag="ACIZE5_001636"
     CDS             29085..29975
                     /locus_tag="ACIZE5_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 family protein"
                     /protein_id="HGC6108765.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            29998..30213
                     /locus_tag="ACIZE5_001637"
     CDS             29998..30213
                     /locus_tag="ACIZE5_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108766.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            30225..30566
                     /locus_tag="ACIZE5_001638"
     CDS             30225..30566
                     /locus_tag="ACIZE5_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108767.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            30566..30937
                     /locus_tag="ACIZE5_001639"
     CDS             30566..30937
                     /locus_tag="ACIZE5_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108768.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            30930..31325
                     /locus_tag="ACIZE5_001640"
     CDS             30930..31325
                     /locus_tag="ACIZE5_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HGC6108769.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGEVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            31327..31704
                     /locus_tag="ACIZE5_001641"
     CDS             31327..31704
                     /locus_tag="ACIZE5_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6838 family protein"
                     /protein_id="HGC6108770.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNNPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            31705..32313
                     /locus_tag="ACIZE5_001642"
     CDS             31705..32313
                     /locus_tag="ACIZE5_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="major tail protein"
                     /protein_id="HGC6108771.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            32313..32654
                     /locus_tag="ACIZE5_001643"
     CDS             32313..32654
                     /locus_tag="ACIZE5_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108772.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            32896..35685
                     /locus_tag="ACIZE5_001644"
     CDS             32896..35685
                     /locus_tag="ACIZE5_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HGC6108773.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANPFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            35675..36415
                     /locus_tag="ACIZE5_001645"
     CDS             35675..36415
                     /locus_tag="ACIZE5_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HGC6108774.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            36412..>38249
                     /locus_tag="ACIZE5_001646"
     CDS             36412..>38249
                     /locus_tag="ACIZE5_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HGC6108775.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCGIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWR"
BASE COUNT        12956 a         5839 c         7831 g        11623 t
ORIGIN      
        1 aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa ggggtcgcag
       61 gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag ctcagctggg
      121 agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct ccatttcatt
      181 taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc ggttcatacc
      241 cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga cctttagctc
      301 agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc tacaaggtcc
      361 attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag ggaacggtct
      421 tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc tcctttttca
      481 tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga aggtcgtagg
      541 ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg taggggttaa
      601 catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc gccatgcggg
      661 tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg attctcgtca
      721 cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg cctgataagc
      781 gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat tggttttggg
      841 gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg aaaccggcgc
      901 gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc cgttggtcaa
      961 gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt acgggtcatt
     1021 aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa cggtcttgaa
     1081 aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct ttttcatatt
     1141 atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt cgtaggttca
     1201 aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg ggttaacatg
     1261 cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt ggctcggtag
     1321 ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt ctgtcccgcg
     1381 ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt gtcgcgagtt
     1441 cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt tagagcgcac
     1501 gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt ttattggccc
     1561 gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc gaatcccgta
     1621 cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga atgattttaa
     1681 aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga cagttctaat
     1741 gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag aaaactgttt
     1801 tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg gagatgcctt
     1861 gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta tttacatcag
     1921 aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat gcaatcttgg
     1981 atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct gtaacaactg
     2041 gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt caaaaagtcg
     2101 tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt gatggagata
     2161 cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa ggagttgatg
     2221 aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt ggtgctggtg
     2281 accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg cctttaccaa
     2341 tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca aatgaattaa
     2401 cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat caaggacaac
     2461 cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta gataatgaaa
     2521 caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct gaattattag
     2581 atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt ggtcctcaag
     2641 gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt tatgctcgtc
     2701 atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct gccagctatg
     2761 ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa gcagaagtac
     2821 agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat actttcggta
     2881 ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc gatcttcggc
     2941 cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa acagctgctt
     3001 acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac aaagtagatg
     3061 cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc caagtggtgg
     3121 ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt atttatctat
     3181 ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca aatgttactt
     3241 tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt acaatcgtaa
     3301 caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg aactgggtat
     3361 tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa cttgcggata
     3421 aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc ggttcgttat
     3481 tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt caagggatgg
     3541 gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat tctattgaaa
     3601 agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt gtttttggac
     3661 cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt tttatcaatg
     3721 tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa ccaaaaatca
     3781 tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc atgcttgtct
     3841 cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt gtttctgctt
     3901 tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa agagctaaag
     3961 atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc aacttggctg
     4021 cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg tggatgcaag
     4081 gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta tcactagtct
     4141 ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact cattgggtct
     4201 tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt atgcctttca
     4261 gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc ttaggtgtga
     4321 ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag cttggtgtag
     4381 caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt tctatttttg
     4441 gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta acaaatgatg
     4501 cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat gcggatattt
     4561 tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta gttggcttgt
     4621 tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt ggtaaaataa
     4681 aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa agttattcaa
     4741 aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa tatttattcg
     4801 aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac aaaaaaggtg
     4861 attggcacca gttcagagca agagacaacg gatatacctg ttttatattt acttcatgga
     4921 atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta tgtagcaaac
     4981 tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga tacagtttat
     5041 gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca tgaattattc
     5101 ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat gggcggatat
     5161 ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat ctctctttca
     5221 ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa agcatctttt
     5281 tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga tccgcaatac
     5341 ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat ggcttgtggg
     5401 gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca ggaacaaggc
     5461 ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg ggaccaatgg
     5521 attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct taaaaagata
     5581 gctcctatag agatcacaaa catagtgatc tctataggag cttttttact gctcgttttc
     5641 tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg ttagaaagag
     5701 tgctttttca ttcaattctg catgggactg catactttct ttaaatccct ctaattgatt
     5761 ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat ttccgtccat
     5821 aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa tcaataaatt
     5881 gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac gaacaagtaa
     5941 ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag tattgatttc
     6001 taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca tatactgcag
     6061 caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt ccattgtttc
     6121 agccattttt tgcaagagct gttgtttgtt tttgaaatac caatataaag caggtgcttg
     6181 aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt gtgtttcagc
     6241 caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt ccattttatc
     6301 aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt ctaattttac
     6361 agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat gaaattaatc
     6421 ttacgacatg cgaaaaaata taaagtatct gtttttattt ccttgctgtc cgtagcagtc
     6481 atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga agctattatt
     6541 acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct ggctttgcta
     6601 ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca aggcgtaagt
     6661 gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg aaatatcgaa
     6721 cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca aatccaaaat
     6781 ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat tggtgccttc
     6841 attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct tatcgttacg
     6901 gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat gatcattcaa
     6961 aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat tcgtgtagtg
     7021 aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag tgaggactta
     7081 acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc cttcatgctg
     7141 gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt taaagatgat
     7201 cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat tatgatggca
     7261 atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc gctgaagcgg
     7321 attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc agaacaagag
     7381 ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga ggatacagat
     7441 acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat cgtcggggcg
     7501 actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga tccgacagaa
     7561 ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag tttaagacaa
     7621 acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc tcaaaacttg
     7681 cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc tattgctcaa
     7741 gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga agaacgtagc
     7801 agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt tatcggtaat
     7861 ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc tgaaaagctg
     7921 gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat cgcacaaaaa
     7981 attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag attagtcggc
     8041 gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat ctttgaaact
     8101 caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa tttttctatc
     8161 actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg atcattgcta
     8221 cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa ttagctaatt
     8281 acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct gtaatatgga
     8341 aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt attttgttca
     8401 cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac aaattggaaa
     8461 aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt cgttttacca
     8521 gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc atcacgaatg
     8581 ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag ttagcttggg
     8641 ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc cgcaaagcac
     8701 ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat atggatgaaa
     8761 aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg attgaaggat
     8821 tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct tattctggtc
     8881 tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt atctttttcg
     8941 gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc ttagttgtga
     9001 cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca tctggataca
     9061 gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt gatgaaaaag
     9121 atgaagtcaa accagaaaac ggtaaagcat ttgatggtgt tgaaaaaggt cttgcgttgc
     9181 agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc tcgatcaatg
     9241 tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa acgacgatca
     9301 tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc gatggaatag
     9361 atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt ttgcaagaat
     9421 ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg gacgcttcag
     9481 atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc atgacgttag
     9541 aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca ggtcaaaagc
     9601 agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt ttggatgaag
     9661 caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg gatgaagcaa
     9721 tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg aatgcagata
     9781 gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcat gagttattag
     9841 cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa agttaaatta
     9901 aaagaacctc gttataacgg ggttcttttt atatatttta tgttgtttgt ttttataagg
     9961 ggcagaaaag gggcaattta aatttctatt tttcctagtt tttctactag ttgattttgc
    10021 atatttttag ttgtatgagt ataaatcttt aatgttgttt ttgaatcttc atgtcctaca
    10081 cgatccataa tggcttttaa tgggattcct aattctgtaa gtagagaaat gtgggaatgc
    10141 cttaacatgt gagaagaaac ttttttatct aggtttaatt ctttggatac tgctcttaaa
    10201 gattgattat atgcttgaat agatatcggg ttaccatttt tagagatgaa aatgtattta
    10261 tctttattat tcttaattaa tttgttttct tcaattaatt gatctatgat ttctttagca
    10321 ttacttgata attcaatggt tctataagaa cctgtatttt tagttgttgt tttaattttt
    10381 aactcgtaat cataagtacc agaaaccgta attttattac catcataatc agattcagtc
    10441 aaagatatca attcaccata acgtagtcca gttaaaaaca aaaatttagt aattaaagaa
    10501 taacgtgact gttgatgtga acttttttgt ttactagcaa tcatttgaac ttcttctttt
    10561 gataaataac catctttttc tttttttatt tcttcgtttg tcttaggttt tcttgctaaa
    10621 gaaaccccat ttacgggatt atattttaat ccatatcgac ggttggcgaa tttaaaaatc
    10681 attcctgtaa aagtttttaa atgtattaca taattatatg ataaattttt ttcaaaatag
    10741 tagtaatcta gcatatcttg tataagatta ctattaacgt tttttacaag tacatcatct
    10801 tttatatatt ttgaaattaa tgatagataa acctgagttg ttcgatagga actttctttt
    10861 acagttggct tgtatttttc atcccattta gtttttaatt ctccaaaagt tagtggtaat
    10921 tcttcatttc gttttatttt ttctgcgatt ttttcattca aaagtaagtt agcttgattc
    10981 caagcttggc gtgaattgct agataaagta acggacactt ttctcttttt ttcagttaag
    11041 ggatccgtat aacgttcggt gtacttaaat tttttgtcat ttattttttc taaccacatt
    11101 atttctattc ctttcgaata tacgttccta ttaattgtta aaagaaaaag cccgaaggct
    11161 ttttatatat ttaatctttt gacaattcta aagatcgtct atattgttca gctttagcta
    11221 attttgtaaa tgttactgtt ccattataat tttctaaaac aactttctct atttcgtcta
    11281 gtgaaacttt gaaaaattct tttctttgat taattttatt aacttcttgt tttctaaaat
    11341 gattatgcaa tttagtttcc aaagacggag cgtcctctga aaaaatcatc gcatgaacgt
    11401 caaattcaaa tggaaccgat gcactactca attcttttat tctatccata ggttctaatc
    11461 ttctagtcat accaatttta tatatgtctt caccaaaaga cccaatatta ctaattacat
    11521 acacataacc ggctctagta tttaattctc tttgtaatac attttcacgt ataacttcta
    11581 attcttttaa tttttcttcc agttcttgaa ttttatttgc atataattct ttttccacat
    11641 ctgcattagc tttttgcata tatgcgatta atttggaaat ttcagaattg aattgacgtt
    11701 gttctttatc aatacgtttc ttttcacgat caatttctct acgaactttt tcctcttcta
    11761 tcatctgttc ttttattgct ttttgttgtt ctttttcttc ggtaattttc actaaataag
    11821 agtaatgaag ttctagttct tgaagtttaa actctaaaag acccttcctt aattcagcat
    11881 tgtcattctt gaataaatta ttaattttat caaatatttt tatgattttt tccctagtcg
    11941 agtctatatt agaaatagtt agtttattga gtaatccttt cacttctgaa tcaaatggaa
    12001 tgagcatttt tttctttaaa ttatttttct ctcgtttatt taaaataaga gggacagaaa
    12061 cagcatcgtc aataatatat tccttttctt ttaattttaa caaagaaagc ttatttttta
    12121 tttcagaaga tgaagtttct tctatatttg aaacgataag tgaagaatag acatttttta
    12181 atgtttcatc atacttttga tttatttcat catttaaatc ttctttctct ttttttaata
    12241 aaataatatc attttttaac atagtaattt gtttatttaa atctgatagt gtttcttcct
    12301 tacttaatat aaatctttct ctatcatgta atttatttag tttttcatca tttttttgtt
    12361 ctaattcata agcttctttt tttattgtgt tagctttcga cagtttagtg attcctataa
    12421 ttaataaaat aagtccaatc aataataaca ttcaaaactc ctcatttctt tgatataatt
    12481 attgtagagt ttactcagaa atgaggaaag agtccatgtg aaagcatggg cttttttatt
    12541 tttaatgttg taatactaaa tgttcaagat tatgaggaag ccctaaatat tcaataattt
    12601 ggaactgact catatcagat aaatcttgtt catctattgt tctagttaac atttcaattg
    12661 caaacatatt agcttcagct tctataccat aaatcataca actaaggttg tttgctctaa
    12721 aagctgctgt gcaaatacct ttatggagtc taacgtgggc tatttcatgc cataatacaa
    12781 atcttttcat agaaggtgat aggttttgat taattaatat cacataacat cttttattgt
    12841 gtatcgtttg tcctaatgtt ttattcccta aatcagtttc aattaaatct atatcagaat
    12901 atttgattat tttatatgga ttaatcgcat cagatccaaa ctctacaaat aatttttcta
    12961 tttcttctaa tatccagtat ttgtttaaat gcataccaaa gcccacctat tgacgatatt
    13021 ttttaggagt gaattttttc tttgctttaa ctttggttaa ggcaagtgca agttgaatgg
    13081 catcgtataa tttttcctta tcttcatcgt ctaaaggttc accataataa tttgtttcag
    13141 catctgaatt caagccttca agtaattttt cagcttgtaa agcaatatct tgtttatctt
    13201 tttctgttaa atcataataa tggcgtttat cagtacgtcc taaaagataa tcagttgata
    13261 cattaaagta atctgcaact ttttgtattt tatctccaga tggagtactt ttattccatc
    13321 tagacatgct tccatttccg aaatttaact ttctttcaag ttctgccaac gtcattgaac
    13381 gttcttttaa taagattttt atacggtcta atagcatagg atatgcattc ctttcaaaat
    13441 accgacaaaa aaagtatttt tctgcaaatt atctatttac aaatagagaa tttgcagtta
    13501 tactagtttt gtaagcaaga tatttacggc atacaaagac taaaagcaat aaactaatag
    13561 tctccccaga catcagtaag ctcgcttttt gtgcgctgta ttttgtatgc ttacataata
    13621 gcatatttgc agtttttgtc aaacttatta gacaaaaata ttagaaaata ttcgataagg
    13681 gggtatgaag catgacttta aaacagcaag tattaattgc tttagtaaag aaaggttgga
    13741 gtcaaagaga gttagctcga cgaatgggta tatcaattac ttatttacga gatatcttca
    13801 tcgaaaaaag aaaacctaag gaacgtttaa aacaaatcga agaacttttg gatatcaagt
    13861 tagaagtaga ttctaatgat cagccatcag aacaggaggc gtaaaaatgg tacaacgttt
    13921 gagcaaagcg gagtttaaag agaaatataa gtattctgaa agtacttatc aaagaagaat
    13981 gaaggaattt aaaaaatcac gttttagtga ggggtataac gcagttactt ccaaagaaat
    14041 aacaattgat gtcgatttat atgaacagtt tagaacatgg cgttctaaaa atcgatttag
    14101 agttagagct gtttgttaat agctaaaaaa tctaaattca ccacttctga aaagaggagt
    14161 tgctgctctc ctttcaagtt tgccaaagtc cacgtttttt cattttggca actcctcttc
    14221 ttggaggtgg tgacggcgag agacgaagga gggatgacat gaaggaagaa tcaaaaatag
    14281 ggattttgaa tgagaacaat tacacaagat taattattga aacagaagaa gggaaaaaag
    14341 tagcagaagt tacattgacc gatgcaactc ctgctgacgg ttatcgtatt cgattaactc
    14401 ctaaatatga ttaacctttt ggtgggtgtg gatcgtttcc gtgactatca cggctttgaa
    14461 tttttccatc tctgccatga ataaatagct cagatccttg atttttagaa atctctctag
    14521 cgatttttac tgcttctgat tttgtattag tatgtgcagt cgctttagaa tttccagcac
    14581 ctttgacatt ccaaccacca ttggaattag gtacaacatg ttgatttttt cccatagttt
    14641 tcacctccat ttctatagaa atattttatc aaatagaaat ggagaaattc aataaacgaa
    14701 aggagaagtg atatggcata taccttgcaa caagaacatc aaattctcgg tttgattaaa
    14761 caacgcagga aacaattaca agatgaccgt gcagcgctta gaaaagccga tgagctatca
    14821 gataggcaag ctgaactaat tgcttctgaa cttgaggatt tgagaatgct agaaataaaa
    14881 aatagggaga ttagattatg aagaagacag acacactttt tataggattc attttggggt
    14941 tattagtgat tgtagcgcac caaagtatta tcgggggaag cttgttcgca gcattgatgg
    15001 ttttaatcaa tctgcttgat tcaaaagaaa ggagcaacta tggcacgaga agaagcgcta
    15061 aaaatcggta aagtgattgc tgataatcgg tggggaaata gccgccctat tattttaagc
    15121 aagcaacata tcgaaaagca aaaagcatgg caacaaataa aaaagtgact ctgccagcca
    15181 gcaaagagtc acatacaaat ttataaaact aggagaatta tatcacatga ataagaaaat
    15241 tgaaaatctt atcgaagaat tgaaacgtga atgccaaaag caaggtgttt ctattatttg
    15301 tacagcccaa aaagaagggg aacttaaaag tctcgtttat ggtgagacaa cagaaatttt
    15361 actttgtctt gctatgcaag aagaacattt agatgaaaat ctcccattgt cagcacatat
    15421 tatgcgtaga attgctgtgg atgcttacga acaagcgaaa aatgaagaag aaaatcaacc
    15481 ttcaaatcat acttttgtta ttaataacaa ggaagattta gctgatgtga tgactcgtat
    15541 tctcaagggg gaatttcaat gatgaatgaa aaaacaattg atctactcat tattttattt
    15601 ttcacgttag tgattgtagc gaaaagttat gtaatctttg gcttgttatt cgcaattacc
    15661 atgcttgtgc tttgcgtgtt agcaagcaga aaagaggtta aacatgaacg agttagcaaa
    15721 tcttgacaac tatttaactg atcctgatta tgctaaacca ccatatgaag caccaattga
    15781 tgaggaggat gaagatgagt aaatctacct tagaaatgag ccatcaagaa tggcttgaag
    15841 accgtaagaa aggcatcgga ggttcggatg ttggaacaat tttaggattg aataaatgga
    15901 aatctcctta tcaactatgg ctagaaaaaa caggacaagt agtacttgaa gaatcaggaa
    15961 gtgagcccgc ttattggggt aatgttttag aagaagtggt tgctaaagag tttcaggaac
    16021 gtacaggcaa aaaagtacgc agaagaaacc aagtatttga acatccatta catccatttt
    16081 taagagcaaa tattgatcgg gaagtagtgg gagaaaatgc cattctggaa tgcaaaacag
    16141 ccaatcaatt tctcggtaaa gaatgggaag gcgaagaggt accgcttagc tatctctgtc
    16201 aagttcaaca ttacatgaac gttctaaaca aagactattg ttacatcgct gtcttaatcg
    16261 gtggtcaaaa atttatctgg aagcggattg aacgagatca agagctgatc gatacaatca
    16321 ctgaacaatt agtagagttt tgggaaacaa acgttcttgg aggtatcgag ccaattattg
    16381 atggtagtca agcgacagct gatttcttga aagagaagta tgcagatgtt gaagacgttc
    16441 aaacgacgtt accaattcat ttcgatgaac tagttgaaca gaaaaacgaa ctcaaacgga
    16501 ctaagaaaga aattgaatca gctatccgtc aagtagacaa cgagattatc agcgagctag
    16561 gtaaacgtga agccagtatc ggtatcactc aaaaaaacat catcagttgg aaatttgtcc
    16621 gtacgagacg tatgaactcg aagaaactag cagagaaata tccagatgtc gcaaatgatg
    16681 aagagattta taacgttact gaatcaagaa ggctaaccga aagggagatc aaataatatg
    16741 gcaacaaatg aatcgttaaa aaatcaattg gcagcaaagc cacagaaaca agttgcacca
    16801 ggtcaattag gacttaaagc tttgatgaat acaccaacaa tgagaaagaa gttcgaagag
    16861 gtgcttcatg acaatgctaa tgcttttatg tcgaatgtta tgactcttgt atctaatgac
    16921 agttatcttg cagatagtga accgatgtct atcatgagtg gtgcgttaac tgctgcaaca
    16981 ttaaatcttg ggctagataa gaatttaggt tatgcatatt tagttccatt caatagtaaa
    17041 aacaagcaaa caggaaaatg ggaaaagaaa gctcaattca tgcttggcta taaaggatat
    17101 atccaattag cccaacgatc aggtaaatac aaagcattaa atgtgatcga agtttacgaa
    17161 ggagaactaa aaagctggaa ccgactgaca gaagagtttg agtttgatcc aaatggtaga
    17221 acgtctgatg aagtcattgg atatgttggc tatttcgagt tactgaatgg attcaaaaaa
    17281 actgtctatt ggaccaaaca agaaatcgaa gctcatcgga ttgctaacaa taaagatcgc
    17341 gataagacaa agttaagtgg tgtgtgggca tctgattaca atgcaatggc acgaaaaact
    17401 gttttgagaa atcttctttc taaatgggga atcttgtcca tcgaaatgca agaagccacc
    17461 acatcggatg agagagtcca aagggttcaa gaagacggca gcattattgc tgaaacagaa
    17521 gttgaagaag atattcctga aagaaaagaa gcagaggtta tatctgaaga aaatgaagat
    17581 gtacaaactg gattatttga tgcatctaat ccgccgttaa acaaataatg agggagcttt
    17641 ctcccttgct tttctagagg agaaatacga atgaacacag gatatgtcaa attacatcga
    17701 aaagtgatga attcattcgt ttggaccaat ccttatatgt ataaattatg gaacttgtgt
    17761 ttgatgaaag cgagtcatga gaatcgcaag atacttttta atggaaaaga gatacaagtg
    17821 aacagcggag aattcgtcac agggcgcgat gctatcacat ctgagatgaa cgaaggcgtg
    17881 aaacgtgaac atcaagtgaa cagcggttct gtatggagat ggctaaaaca atttgaaaaa
    17941 aacggaatgt tgaacatcaa atcaactacg aaatacagcg ttatatcaat aaaaaactgg
    18001 tctttgtacc aaagcagtga acaacaaatg aacatcaaac gcacaacaag tgaacaacaa
    18061 gtgcacacaa acaagaatga aaagaattat aagaatgaaa agaataataa aacatcatcg
    18121 tcgcaaccac gcaaaaagcg tgtttacgac accgactcag tttactacat tctcgcggag
    18181 gagttattca aacagatttg tcagaatcag gaaatcaaaa agccgaatct gcaaagttgg
    18241 gcagatgaca ttcggaaaat gatcgagatc gacaagcgga ccgaaaacca ggtacgggga
    18301 atgattgaat ggagtcagca caatgtgttt tgggcatcga atattttatc tgctaaaaaa
    18361 ttgcgagaaa aatacgacac aatggcagcg caagcaaatc gtgattataa aacaaaacaa
    18421 actaaaacgc ttgaatacga gaaatttagc acagatgagt tgcctatttg agaggaggcg
    18481 taggcatgga aactgttggg gaaatcatgg aaaagctgat acagaaagtg cttgtccaac
    18541 gtggcgaatg tcctgaatgc ggacagcctt tgtatggatg gcgtacgaag aaccctgatg
    18601 gctcagaacg ttgtaagcca acctgtatgc aatgtgggta taaagcattg cgagttcagg
    18661 aagacttaca aacagaacga atttacaacg agagcctgaa agcaagagca atcaattttt
    18721 tcaaaggtgg ttctgttgtg cctaatcaag cgttgtttga ttgcacattg cagaattatc
    18781 aaattgtcga tcaagaaaca agacaagcgg ttgaagtaac caaacgcttt gttaattcag
    18841 tcttgttagg aaatccaagt caccttgttt taactggaaa acaaggaaca ggtaaaagtc
    18901 acctagcgat ggcagcggct tgggaagtct tgaagcgatc aaactacgat aaaaaaatct
    18961 tatttatcgg gttacaggaa atgctggatc aaatcaaatt ttcgtacaac aatcctgaac
    19021 tcagaaaaac gattgaggga tcgttgattg cagatatcaa aacagcggat ttagtcatca
    19081 ttgatgatat cggttcagaa ctaggaaaag atgcatcaga tagtcgagcg tttggcataa
    19141 acacgctaaa ttcgttcttg gatgcacgac agaacctagc aacgattatc acaacgaact
    19201 tgcttggtga agaactgaaa aaagcttacg gtacgagaac aatatcaaga atgtttgtca
    19261 actctgatgg atttacgatg gtattttctc aaacagcaga caagcgcata aaaccagtca
    19321 aaggagcgat cgcatgaatt tgactaaaca agaaaaaaga atctgtcgtc agataatgtt
    19381 gcaaattata ggtgatcgtg acatggacga attatctcaa caagagagtc gaatggttcg
    19441 gaagataagt aagctaatta tttatcggga tacagaaaga tttctcactg ttttaggtaa
    19501 cgtctacgag aatccagagt tattggaggt agagtaattg ccaaaaatat tagatgcatg
    19561 ttgcggtagt agattgttct ggtttgataa gaacaattct gacgtaacat ttatggattg
    19621 tcgtcagcag tatgaagaat tatcaacagg tcatgtgatc aatgttgatc cagatgtggt
    19681 cgcagacttt cgcgatatgc cttttgaaga tgatgtgttc gatatggttg tatttgaccc
    19741 gccacactta agacatgtcg gcgaaaactc atggcttgcc aaaaaatatg gaaaattaga
    19801 cgaactttgg ccagaagaca tcaggcaagg ttttgcagag tgtatgcgag ttttacgacc
    19861 ttcaggaaca ttaattttta agtggaacga ggaacagata ccactttctg atgtgttaga
    19921 ggctattgga gaacagccat tgtttggtaa taaacgaagc aaaacacatt ggcttgtgtt
    19981 tatgaaaaaa ttcagctaac ggaggaaaca aaggaggaaa agtaatgaag attgtattaa
    20041 ataaatgttt tggtggcttt gggttgagcc atgaagcaaa aatggaaatt tttaaaagaa
    20101 aaaatattga agtattccca tacatcaata actttagcta tgactcagat gatgaataca
    20161 cgagatacac aggccaaaag ctaggttcga tggattttat ctactatttc aaaaaagacc
    20221 cgaaaatcga caaagttaca ggaatttata gcgaaattga ccgactgtac ggaattgctg
    20281 atgattccag tttttcaagt gattcaaaca gaggtgataa ggacctcgtt gctgttgtcg
    20341 aaaaactagg aagtgaggcc agtggaccat atgcaagtct taaagtcgtt gatatacccg
    20401 atggggctga gtgggaaata agtgattatg acggcgttga aactgcacat tatggttttc
    20461 aaacaggtag tatttagtcc actaatgaca actaaagagg aggcagaagg atgagtgaag
    20521 atgaatactt tgaacagtag tctattaacg acagagattt ttaactggaa aggggtgtag
    20581 tcatggacgc atcggaagta gtaaataaaa ttaatagtct caaagaggtt ttcggagacg
    20641 tcgaagtagt gataaacgca caaggctatg acaacgaatt ttttaagcag attaccgaca
    20701 ttagcattca gcaaggaatg gaagacgaag acggaaactt tatcgatgaa gtagccattt
    20761 tagtgacttg cgagtaagta attgacagct aaagaggagg aagcggaatg aaactaaaag
    20821 acggatttta ctccagcggc cacggcatcg gcggtttaat gctagatatg ccgacaaaga
    20881 atcctaaaac acgtaagaaa ccaaaattca aagtcggtga catggttcgc tgcgaagcag
    20941 aaggattcat ctatccattt cgtggatatg tagaacacgt ctataatcac tcagcaatca
    21001 ttcgcattga aaacacgatg gaatgtgata agtggttagc gaaaagcaaa gagaatttag
    21061 cagtggtgag attggtggac atggaagtta taaaatctta attttgcttt tttacaacta
    21121 tcctacaaca atgagcgtta ttccacaact ggaaggagaa gaggcaattg tgaacatttt
    21181 agagaatata gatattaagc aaacaaggaa aaatgctaga cgattactaa aaagatacag
    21241 aaatttagaa cgtttggtcg gaccagtgaa aatagacttt tccgtgatga ctgttaccaa
    21301 aaatttgaaa ttcacaattg acagtcaaaa cgaagaaatc attgaagcga taagtactcg
    21361 agattcggtt atcgaagcat taacacggct aagtagaatc catttccagg tactttatta
    21421 tagttattgt tttcctaata agatgtcaat gtatcaaata ggagaaaaat taggatattc
    21481 cgatagaact atcgagagaa tgaaggcagt agctttggtt gaatttgctg aggcgtataa
    21541 atcaggagaa ctcatttcac gtacaaaata aaaaaagtcg gattcctccg actatgaata
    21601 atatttccga cataagtatt atatcataat tgggggaatc agaggatggt acttttcgat
    21661 gtaaagaaat atgagacacc aagcgcgaaa gatgttgata tggaacgcac aaaacataat
    21721 gtcgctgtgt ttctttcagc atatctatca gctagatgta gagtagggca acatcgagaa
    21781 ccaaaagtga cagcatctta ttccttggtt ccaccttcta cagctgatca tatatttgaa
    21841 gcagaaagaa tgctgatcga taaagaagaa gcacaggaag aatttgagta tctgcataaa
    21901 ttgtttgttc gaggctattc agcgatacag catccgcata agcctgatgt gactgaaagg
    21961 cgcaagaaga tattctatga tcgttatatc aatggtctgc ccatttatgt aactgctcaa
    22021 aggaataata ctagcgaaga atcggttaaa gtagaatcaa acagaattat catccaattt
    22081 gcttcatcgt tagaactggt tgctttcaag tagccagttt ttacactttt tatacccttt
    22141 tattaccaat ttggtttcca ttttatacct tttttatacc aatcacttac ctattcaacg
    22201 ttgtattatg atagtgtcga aaaattagga aacaggatcg acaaaataaa atgtaaggga
    22261 ggaaatctcc ctcatcgttt aattaagctt cgataggcag caacggaaat attaagaata
    22321 aggatgtgaa tttcaactcc ttctaaattg ttcttattat ctatcatccg ttgctgtcta
    22381 ttgttttttt aattattcac acgataacta aaggtaagtg aagagaaatg attccattaa
    22441 taatttcaat ttttgcgctt tgtcttaatg tatatatgat tggatttaaa aatgggcaaa
    22501 ataaaaaata gtagcagcca agaataattt tatagtgtca ctgtggcgga aagggtagac
    22561 gctaagcatg tgtgctaggt caatgcttcg gcaaccatgc aaggttcgat tccttgccag
    22621 tgactttggc aaccgaggca tcggcggttt aaaaatatag gggtgcgcaa tttcgtacgc
    22681 gttttgtgca tcgtgtaggt tgctattaca taactggtta ggttagattg agatttggga
    22741 ttcggtacaa atgaatcgtc aaatgtctca agcacaggat cggaaacgtc cctgcctgtg
    22801 cattacatat tagatcactc tttgagtggt ctttttcttt acataaagga ggctacataa
    22861 tgagaaacta ctggtatgta tcgctaacta atgaatatcc tcgaaccatt gatgattgtt
    22921 cagtgcgtgt tgtgcgttct gtacaaatca aagggaagta ctctattgtc gaaatgggga
    22981 gagaagcaga accatgtgag attgatgcgt gcaagctcgt ttattgcggt catggtttct
    23041 atgatgaacc aaacattcaa aataatatta acaagaattt gagggattag aatgcaagaa
    23101 atggcttaaa aatctccaat caggacaaat caagttagac aaagtttccg atttaaagat
    23161 attgattgaa gctgatttaa tgctaaaaga tattgaaaat tagaaaacaa aactcaacct
    23221 aaacagaatg tgaggtggtg tgtattgaat ggcaagacaa cgtgatccaa gacgtgatga
    23281 agccaaaaga atttggttag aatccaacgg agaaaagcag ttaaaggaaa ttgcatctga
    23341 attaaatgtt tcagattctc aggttagaaa atggaaatcg caagacaaat ggagcgctga
    23401 attgattagt aacgttacca atggcaaaag taacgttact aatcaaggtg gcgctcctat
    23461 tggtaatcaa aatgctaaag gtaacaaagg aaatagccga gcttctccgc cagtgggtaa
    23521 taaaaacgct ttgaaaacag gtgagtatga aacaatattt tttgacacgt taaccgataa
    23581 tgagaaggac atctattcta gtttgaatga tgatccttct tttgctttgt ccgaagaaat
    23641 acgacttctt aaaataagac aacttcgaat gatgaaaaga atccaacaag ctgaagctgg
    23701 actaaatgat gaagaagtcg aacgattgca gcagctaaga aagattaaaa ctccgattga
    23761 aaaaaatggt aaaaagctag aaatcaagcg tgaggttatg caagatgtgc agattagcag
    23821 aaaaaaacat cgcaaaattg atgatattct ttcaattgaa gattcattga ctcggattag
    23881 caaccagtta gctaaagcca tcaagcaaat gaatgaactt tatatgaatg aatacagaac
    23941 tgatttaatt aaagctcaga ctgataagat ccaagctgag acaaatgaaa ttggcggaaa
    24001 taattcaggt gaagaaatag aagaatggaa acaggcagtt ttaaatgccg caaacaaacg
    24061 ggcggtgaaa gaaaatgaat aatgaattta ttccttttgc tgatattggt tctgccattg
    24121 attattacta tgataaacca gtagcttttt gccaagatat tttgcatttg aatcctgatg
    24181 aatggcaaga aaatgtttta aatgatttag ctgaattttc aaaggtttct gttcgttctg
    24241 gtcaaggagt tggaaaaaca gcattagaag caggagcaat actttggttc ttaacgtgtc
    24301 gaccctacgc taaagtaata gcaacagctc cgacaatgaa gcaactttac gatgtacttt
    24361 gggcagaggt agctaaatgg ttaaatgata gcttgatcaa aaacttactg aagtggacaa
    24421 agaccaaaat ttatatggtt ggtgattcag agcgttggtt tgctacggct agaacagcga
    24481 ctaaaccaga aagtatgcaa ggttttcacg aggaccatat gttgattgtg gtagatgaag
    24541 cttctggtgt gtctgatcca attatggaag ctattcttgg tacgctatca ggttttgata
    24601 ataagctgtt gatgtgtgga aaccccaata atattgaagg tgtcttttat gattcccata
    24661 attcagaccg tgataaatac agagttcata aagtatcaag ctatgatagt aaacgtacaa
    24721 acaaagacaa tatagaaatg attcttaaaa aatatggaaa agaaagtgat gttgctcgtg
    24781 tccgtatttt tggagaattt ccgaaaggtg cgttggattc atttatcagt cttgaaacag
    24841 ttgaattggc tacagaaaaa caaattagtg attctttagt caataaaaca aaggttgctc
    24901 atattggtgt cgacgtagct cgatatggtg atgattctac gattctcttt cctagaattg
    24961 ctaccagggc attggagtat gagaagtatt caaaacgtag caccatggaa acaacaggat
    25021 atgtcatcaa catggccaag aatctaatga gtcaatatcc gagtattgat aaagtgatga
    25081 ttaaagtcga tgacactggt gtcggaggtg gtgtaaccga ccgcctagaa gaacttatag
    25141 aagacaaaca ttatcctttt gaggtgtttg gagtgaataa cggttcaaca tcagaagacg
    25201 atttttacga taatttaggt actcaactat ggggaaacat caaggaaatg ttagaagaaa
    25261 atatgacagc aaatcttaac ggagaacagc ctgttattga attgccttct gatagttcgt
    25321 taatcaaaga attaagtact cgcaaattca aaatgacaag tagaagtcgt atacgtttag
    25381 aaagtaaaga tgatatgaaa aagcgaaata ttggtagtcc cgatattgct gacgcactgg
    25441 ctttagcgtt ttatgagcca ccaagtcact atcaatttat tcaattttag gaggtgagct
    25501 tttgattagt acagtattat ctttagagag atataagaag ctacgtgtta aatatgcaac
    25561 acaaattgaa gatggaatgt ttgatccgaa tggttttata gaagatatga aaccattttt
    25621 tgctgatcgc gaaagaaaat atctagctta tactagcgaa aagaatgaaa tagataatag
    25681 accaaagcct aacactgata ttgtaaaagt taataataaa cttcatgctg gtatgtattc
    25741 aattgtcgta gaccaagcag tcaatcattt tactggtata cctatcaaat gggattacga
    25801 tgtatcggaa caaaaaagaa cactcattca aagattaaaa gataaattct taaaaaatga
    25861 tatagaactt ccgacagttc cagaagcttt taacaaatta acaagcaatc ttgattccat
    25921 gagattcgca atgcttgatt ctgaaactgc aacttttcaa ggagcttgtg gagtagcttt
    25981 ccgattgcta gagcctgtgg aagaagatga tggttggaag ttaagagcaa gtaatattga
    26041 accttggaga gcagaaagat atggaaatgc cggaatctat atcaaagaaa agtatgactc
    26101 ttaccagaaa aaattttttc aagaaatgaa agttatgaca agaaataaaa ttctgacata
    26161 tgcttgctat ggtgatttga attttgttac aagcggaacg ttcaaaaaaa ttgatgagac
    26221 cgataaccct ttggggacga ttaccttggc agaatttaaa aataatacga atcgttattg
    26281 tgattttgaa gtagctgagg aaattggaga tgcaattgat cgtgctttgt ctgatcaaca
    26341 aaacgaaatc gaacaattta agcttgcgta catgcttgtt actggcacaa caatgagcaa
    26401 aggcactgct aaagaaatga tgaatcagct agggattatc aacttaaaag cccctactgc
    26461 aaaagctgaa tatgtcacaa aaaatttagc aaaagatttc aatgaatatc atatggatct
    26521 attgaaaaaa cagttttaca ccatttgtaa agcaatcgat tttaacgatg aggtgtttaa
    26581 atcaaacagt tctggagaag ctcgcaagtg gcaaatcatt agcctagaag cgaaaacaaa
    26641 tactaaagag caatatttta gagaaggatt gaaagaatgc gcagaaacaa ttgctgcttt
    26701 tcttaagttt catgacaaag tagaaattga gcctgaaaaa attattttta ctttctctag
    26761 atctttgcca actgatttaa gttatttagc tgaagcttta cctaaacttg caccatacgt
    26821 atccaaacga actattcaga gccaaattcc atttgtaaca gatgttgatt atgaaaatga
    26881 aatgatggaa ttggaaagtg gaagtgctta tccagatagt gaatacaatt ttggcggagg
    26941 tggcaatagt gacgatagaa acgaagtatt ggaccaaacg tcgagaactg gaggatcaag
    27001 caaggctcaa acaagaaaat cagacactta aaaaattaac tagtgtattt cctgaagcac
    27061 tgaaagagat acaagcaaaa ctattatcac aagctgactt acacaatatc acttatccag
    27121 aaatgatgga gttttacagt acaagtaatc agaaaaaata tcgtgaatat gtggaaaaaa
    27181 attataagtc attaaaaatg tatgatgcaa aatacaaaga gtttatcgat gaattttttc
    27241 caccatttga ctatgcaaaa gtcaatcgct tattacaaat acgatcagat gtatttaaaa
    27301 ttcttgcaga atatgcgatg gatgcagatg tgaatcaata tttttctgat cgcttagagg
    27361 aaattcttca aagaacatat tcttctaatg ctaatgtttt tgttcaactt ttaaacgttg
    27421 atataccaaa ttatttacca gaaaatgaaa ttaaacatta tttgaactat ccatggtcag
    27481 gaaagacatt ttcaagaaga ctttggggaa atatttcatc gcttgaacag aaactctcta
    27541 atgctattgt aaaaagtgtt gctagtggag aaggcgttat acacgcatta aacaccatga
    27601 gattagactc agaaatttgt gacatgttta agttagaaga atcaaagtat aacaaagcga
    27661 tagaaaatct cgttcgaacg gagtatgcaa aatttgcaca agatggtatt gaaaaatcat
    27721 atttagaaac aggtattgag gaatacaacg tattgactgc aaaagatgag agagtttgcc
    27781 ggatttgtgg aggaaaggca agtaagaatc cctataaact gaaagatgct gtcataggtg
    27841 aaaatcgagc acctttccat agtcgttgta gatgtacgga tgttcctaat ttaccaaaat
    27901 taggaaagga tattgatgaa gaatatgacc gtttatttgg cgatttatta gatgagtttg
    27961 cacatgattc ttttggaatt aatttgaaac ggaggaagta gaatgaaaga tttttttgaa
    28021 gcagtactaa caattaatgt aaatgctgat attgcagaag cctacaaaac agctattgag
    28081 tctgagaacc atcctaatgg cttgagagac cattggaatg gcaattatgc ctacgtggtt
    28141 attggcgatc aaactgttaa ttatcaagat aatactccag ttgataagaa taccgttaat
    28201 ttaacgattc aattattatc tcattcatta ccaaatttaa aagaaacagt tgattggtat
    28261 gaaaagatgg gatgtattgt tgttagaact gactacaaag aaggaaagtc tagtaattag
    28321 gcttttttat tttgtccgaa atgacgttaa actagcgcaa tactgggctt ggttgaatgg
    28381 tggggcgcaa ctattaaaac tcaaagcaat gcggggcgtg aaaacgaatc gtggggcgaa
    28441 aggagaatga gcatgaaaca caaatcatta atgccaatga atttgcaata ctttgccgaa
    28501 ggtgacgatc aaaagttttc ttttgatgac ttcaaatctt ttgtggaatc caatgaagaa
    28561 gctcaaaaat ttattcagtc acaatctcaa agtgttgccg acaaacaatt ggaagcttgg
    28621 aaacaaaata acttagataa aattaaacag gataccatca aggaatatga ggaatctaag
    28681 aaaaacaagt cacctgagca aattcaactg gaaaaactac aagctgaatt tgaagcagaa
    28741 aaagcgttgc gtgtgacaag tgataataaa gcatttgttg cagaacaaat tgctggatta
    28801 gaactagatg gagagttaaa agagtctatt tctcaattta tgctaaataa tcttgttagt
    28861 tcggatacag atttcactaa gaatgctgtt gaaggtttta caagtgtttt gaatgcaatt
    28921 aatgagaaac atgcagatgc attaaaagaa ctacaaatga agtctgcatt tggtggaact
    28981 caacaatcga ataaccaggt tcagcagaac aatgaaacat taacaaatcc agaagaacaa
    29041 ttaggacaaa ttcttcaaca atttaactag gagagtgaaa aattatgaaa aaaacatctt
    29101 taaataattt agagtatttg gatatttcac cagcgattaa tgctatgcaa gtaccaaata
    29161 cacctttttt aagctattta cttggtgctg gaaaaacaga gccagcaaac tcgacagaaa
    29221 ttaaatggcg tgaatatgat atcaacaacg atgattcttc tgaaaaactt gagggcggag
    29281 aatatccaga tgctgaatca ggtcgaactt ggtttaacaa ctatactgaa atttttagaa
    29341 aatcaacctc tgtatctggt acattagatg ctattaatgt gaatggagtc ggaaatgaat
    29401 taactaatca agtagcacta cgtggtatgg aaatgaaaat tgatttgaac cgaaaattga
    29461 ttactggtgt aaaagctgat gaaaatggtt ctaaaggtcg tcgaatgaat gggattttga
    29521 acttgatcaa ttcagcaaat aaggcagaaa cagccactgc gggtgcagta acaagaaaag
    29581 atatcgatac tttatttaaa ttgatgtatg aaaaaggtta tatgggagaa aaactatgct
    29641 tgatttctcc agatatgcag gagttaatga ctgatgagtt agatggaaaa tcaacaaaaa
    29701 ttgttcagtt cggggaaaga gtaacttttg gattgcaaat tggaaatatc gtgtctaatt
    29761 acggtacagg tattgctcta ctagaaccat cattgccaaa aggaacaatt gccgcaatcg
    29821 atactaatta tgtgaaacta cgtccattac gtgaatggag agcagaagaa cttgcaaaaa
    29881 caacggattc tagacgtatc ggtcttgtag gtgaatactc tcttgaatac aatgcttcaa
    29941 actctggggc aattttaaat ttaaagtctg aataaaaggg agttagtact cccttttttg
    30001 ataggaggaa ttacagtggt aaaaaaagat gaaactaaaa aagatgaagt cgtgaaatat
    30061 agagtaggta aaactaaaaa ttttgttggg tttgttcatc ctaaaactcg tagatttatc
    30121 acagcagatt caaataacga atttatcatt tctatagatg ataaagaagc aattgcaatt
    30181 ttggaagatg caattgatgt taatgaaatt taggaagtga tctgatggat gaatcgctaa
    30241 aaacggaaat cattgagtct acaaaagaag attttccaga tttgagtgaa gaacgcataa
    30301 ctaatttatt agaaataatt ttgctagaaa ttgaatcata caacacttgt aaaaatgata
    30361 tttcatggga aaagttaaaa agcgtgatta gtgaagtgtt gtataaaata ataaaaaatg
    30421 aatcagaaaa aacagtatct tcagttagac gtggcgatac aacgattagt tatgcttcaa
    30481 caacaaatga tgttagtgag ttacttctag gctatggtga tttgatacga agagttattg
    30541 gttgtggagg attggagttt ttttaatgaa tgaagcagat attttagaaa ctacttatga
    30601 agatagttgt attattgaaa gactgacgga cattgaagat tctaatacaa atattactat
    30661 tcaagattac aaaaaagtat atgataatcc tatttcttgc gctctttcac aaggtcaaat
    30721 cgatggacta gcagtcatag aagatggaga gatggtaaat gtttcaactg acacatataa
    30781 attatttgtt catcctaaga ttaaactaaa aaaaggagat cgaataacaa taactcaaaa
    30841 ggccagtggc ttaatttttt ctctatttgc tactaagcct ttttactatc ctagtcattg
    30901 tgaagtgaat ttgataggaa gtgagaaaaa tgggtaatct caaatatgaa tcaaatgcag
    30961 aaaagatcat tgagaatttt aaaaatatga ctgtaattgc tcaaaaagaa ggaatatcct
    31021 tcgttaacga ttcaatgaat aaagtcgtta gtttagctaa accattaact cctgtaaaat
    31081 caggtaattt aaggcgagga tatcgtgtag taaaagctag aaaactatca agcggtcgaa
    31141 ttgttggaga agttataaac aatgaacatt attttaaata tgtagaagaa ggtcatagga
    31201 ctaaaaatgg tggctttgtc aaagggaaat tcatgttaac tcgtgcaacg aatcttgcaa
    31261 atatgtctta tattcctcga agatttaaac aaatggcaat aaaaatcgtt aagaaaggaa
    31321 agtaacatga aagatgaaat cattgctgca atcagtagca aattaaaaga aatctatcct
    31381 gatgggacaa tatatcttga ttcagttatg cagtcaacta aagattttta tttcgtttta
    31441 tcagtaatgg aatctggaac tgaaaatgta ggaattgata ttcaaaatgt ttctttctta
    31501 attgatattg cattgattga taataaccct aatagaaatt taattaatga attagtctca
    31561 cgttgtggga ctttttttaa tacgattaca atcgatgagc aaatattatt tccaaaagcc
    31621 tatttacctg atgaagcaga tggtgttcaa catattcgtt ttacattaga atttccacaa
    31681 tatattgaat ggagtgaaag ataaatggga gaaaaaagaa gtaaaaccgg aattatttct
    31741 gtcgaaaaac ctacttggtt tcctttggaa gatgagacag ggaattttcc ggtatatggt
    31801 actgcgttgc caatgggaac agcagtaagt atcaaaccaa cagctaatta tgaaacaaca
    31861 caagattatg gggattcagt ggttcaagat caatttacag cttttggtgg tgcagaagtt
    31921 gaactggaag caaatggata tactcataaa gttttatcta caattactgg agggaaaatt
    31981 gttaaaggtg gtgccttgcg ttctggagaa gatattgcgc aagatggtgc gtttgcatat
    32041 agacgtaaaa aatcgaatgg gaaataccgt tatacggtct tttataaagg acagtttgct
    32101 ctagattcag atgaaacatc aacgattgaa ggaagtaaag taagttttac tcatccaact
    32161 tggaagggtt catttgtaga tgtaccagga cttggatata tgtattcagt tgatgaagat
    32221 gatgaaggcg tggataaagc aatgatcgga aattggttta caaaagtagc aattccaatt
    32281 gaagaagcag aactttcagg aggtacagaa taatgtcaaa atatcaaaca acgattaaat
    32341 taacgaaaaa agacgaagaa ggtaaatatg agcaagtaca atttaaatct gctgaatttt
    32401 taccaggaac agttgtagaa gatgctgcag gagttatgga agaaatgcaa acagcgactg
    32461 ataagcaatc agttaaaaaa gctttaagtc gtgcttattc atttattgca gatactttat
    32521 ttgagggaca atttactggt gaagattatt gcaaaggaat tgatgctcgt gagattgcct
    32581 cattgacagg aaaattattg aagtctgtta ctgcaggttt tgatgaaact tatacagaga
    32641 cgaaaaaaaa gtaagtgagg cgctcaagtc accttcattt aagtattcga ttacttaccg
    32701 agaattagat ataaagacgc aattactcga agcaggttgg acgttaccag aaattgaacg
    32761 tactgacttg gatgagttaa tgcgtctttt tgcttttaga gatgcggtaa aagagcatga
    32821 agatgttgag tactatgata atttcactca attttaggag gtgatacttt gaataacgat
    32881 gacctaattc tgaagatgat actagatgaa tctggtttta ctgccggtat gaataatgct
    32941 gtcaaaaagt tgaactcttt tgatgaaaca atcgaaagaa aaagtagaaa tagtggcagt
    33001 tcattaggta gtatttggaa aatatttgct ggaagttttc tagctagcgg agtaactaga
    33061 atcgtaggag ctggctttga tctaatcaag ggttccataa gtggagcggt tgatcgagta
    33121 gatacgatga ataacgctct acgaaatttc caaaatatgg gatttagtaa ttcagaaatt
    33181 atgaagaata tcggaaagaa tgggctttta tctcaaggta ttcaaggact tcctactgct
    33241 ttgaatgatg cgataagtca tgttcaactt cttgcttctt ctacaggtga tttaactcgt
    33301 tcaactcaaa tatttaaagc tttaaatgat ggaattcttg gtttcggtgg ttcaactgat
    33361 caagttaatg aagctgttat tcaattatct caaagtttct caaacggaaa agtagacgca
    33421 caaacttgga actcaatgat caacgctcaa cttggaccta ctctttctgc tattgctaaa
    33481 aagatgggaa ttacaatggg agatctgaaa gaaggtttat ctcaaggtaa gatttctgtt
    33541 gaagaattcc aaaatcaatt aatagaaatg gataccaaag gtggcggagg acttaaatca
    33601 ttaagtcaaa tcgctaaaga ttctactaag ggaattaaaa cctctataca aaatgcaaaa
    33661 acagctgtta cacgtggtgt tggtgaggta atagaaggat taaataaagc attagtagat
    33721 tcagatttag gtggatttaa gggaattatt gataaagtgg gcagttcaat ggaatcgttc
    33781 ttaaaagtaa ttgctgcaaa tattcctaca gcagtatcat ttttaagtaa tttatttaac
    33841 gaaattcaaa aatttggttc tgctttgaaa ttcatgatgc cctttcttgt tcctgcagct
    33901 accgcttttg gagcgttcat gtttcaactt aaaggtatac cagcaataat aaaaagcttc
    33961 aataatttta agaatgccat aattggcgtt ggaaattcat taaagattat gggggcaata
    34021 gctgctgcta atccatttgt tttaattatt ggtgcagtcg ttggtgcaat agctgttttc
    34081 ggttacttta tggcaaccaa tgaagagctt agaaacaagg ttatatctat ttggaatgat
    34141 gtgaaagatt ccgtaattgg tgtattaaaa aatataaagg actggggaat tgatacttgg
    34201 aattctgcta aagaaatggc atcaaatgca gttgagggtg tcaaagatgc ttggtcagga
    34261 acaaaggaat ggttttctaa cacctggaaa ggtattaagg atggggccac aggtttattt
    34321 gataaaacag tagagacttc aagaaatgca gtcgatagtg taaaaaatgc atggtctaat
    34381 atgaagaaat ggttttctga tacttggcaa agtataaaag attcagccag agaaaaatgg
    34441 aatggaatca aaggttctat tatgtcagtt gctggtccat tgattacagg tataaagaat
    34501 gcatttttac atgttacttt ttatctagag accttatgga ataatttagt tgagattggt
    34561 aaaaacgtct ttgagatttt aaaaaatgtt atacttgcgc cggttttgtt tattacctcc
    34621 atgatttctg gtggatggga agaaacaaaa aataatatga ttgctgtttg gaataatatt
    34681 aaagaaagtg ccataaatat ttgggaatct ataaagaata tatttgtaag ttattttaca
    34741 aatatttatt ttgctgcact caatatttgg acagggttca agcttacatt gataaatatt
    34801 tggaatgaag tggtaaatca agctaaatcg atttggttaa acataaagta tttttttatt
    34861 aatctttgga ttgatataaa atattttgca attcagaaat ggattgaatt gaagttttct
    34921 attattcaaa cttggatcga tttaaaatat aatgccatta ctacttggaa taatattaaa
    34981 cagtttttca aagatacttg gaaaaatatt aaagatacgg catacaatac gtggatttct
    35041 ataaaaaata ccatgattaa tacatggaat aacattaagg actctttctg gaatattgtt
    35101 actggaattg ttaattctgc tgaaaatgca tggacaaatc taaaaaatgg tgtttcaaat
    35161 gctattaatc gggtaaaaga aatctttaat tcgttaaggg aagtcaattt atttgaaatt
    35221 ggcaagaaca tcattgatgg acttataaat ggtgtaaaag aaaagtggaa tgctttgaaa
    35281 gatactatca aaggtattgc aggtaatatc aaaaattgga ttaaaggagc tttagatatt
    35341 cattctccat caagatggat gcgtgatatg gttggtaaaa atattgttca aggtattatc
    35401 gttggtattg ataaagagca aagtaagtta gatcaaacca tgacaaattt agtaaaaaca
    35461 ccgtctgttc aacctgtagt aaatggaata agtcacctac caattacaca aacaaagcaa
    35521 aatatatctg ctagtgaaac aaaagaaatt catttacatt taaatgttta tggagattta
    35581 cctgattcaa tggttcggaa gattaccaca aaaattaaaa cagaattgac aagacaaatg
    35641 aaacgagatg ctggtgcagt aggaggaaca ttatatgcaa cttaagagag gacaattttt
    35701 tattaatcaa cattattctt ctgaatttaa tgtgtatatt caaaacaggc ctgcttctgt
    35761 ttcagctagt cgagtaattg aattgagaga gcgagaagga aatgattcta tcattattga
    35821 taaaggctat tacaaaaatg tgactagaaa gattgagtgt tactataaag caccttcaat
    35881 tgatatggtg caggagtggg aagatcgaat cactgaatgg ttagatatgt cgtcttatag
    35941 tgattttatt ctttactatg atgaacaata tatttatcaa gctgtagtaa tagaaggacc
    36001 tgaatttaaa ggaacaagaa aaacaggaaa tattgtccct tttgaattta cagtgagtat
    36061 tcgaccattt aaggaaaatt acaatggtag atttactatt cgacaaacag aaacttttga
    36121 aatttataac ccagagaagt attcttcaaa accgcttatt aaattgagtg gttctggaga
    36181 tgcttctttt tatattaata aggataaata tgatttgaaa tcgttggaca gagaattatt
    36241 tatagattct aaattagaag aggcttatcg aaaattagat ggtaatttag aacatcagga
    36301 tcaggtcacc ttatttttag attttccatt tttatatcct ggaaaaaatg aaattaaatg
    36361 gacgaaaaat attcattcat ttgaaataat gcctaggtgg tggagaaaag tatgaaacca
    36421 agaatatata gtcctactga aacagatttc tcaacgaatg gcttaggaat tttaaaggat
    36481 tgtacaagat gtggaatata tgaagtagct aatggaaaat atgaattaga gttggattat
    36541 cctttaggaa ctagatttga tgaatatttt gaaaatgact atcaaataaa agcaaagcca
    36601 aacgatcaag aagagtatca tatctttttt attgatgata aagatataga tactttttta
    36661 aatacagtaa ctatttatgc tcagagtcgt acaaatcgac ttggaagacg ggtagtcact
    36721 cttgtggaag tggactctaa aactggtcaa gaagcgatat caattattga aactaaaatg
    36781 gataaaaaat ctgacatacg actttattct gatattacgg ctgtttctag cacaatcttt
    36841 gaagcgagaa atgttttaaa ttgtattgct ggtgaacaag gatcattgct tcaatattgg
    36901 ggcggagaaa ttaaacgtga accatttaag ctttctttgt taaagcgaag aggtcgcaat
    36961 aatgttggaa cgattcggta tggaaaagat atgtctggtt tgaaggtcaa attagattgg
    37021 acaggtataa aaacaagaat tattccatat gctgatcctc aaagtgaagt aggtacgact
    37081 aatcgaattt atggttcgcc agtagatagt gcctatatta ataactatcc tgatgtctat
    37141 acagaacatg ttcagtttac agaagaacaa ggagtaaaag acattaagag cttaaataaa
    37201 atagctaaaa attactttaa aacgatcaat cctggctgtg ataagcctaa agtttctatt
    37261 acggttgaat ttgataagtt gactgatagt gaagaagcga aagaatttgc gaagattaga
    37321 aattatggtc tgtttgatac atttaaaata tatcataaaa aatataatat ttatcttgaa
    37381 tcaaaggtta gtggactaca atacgattct ttatctgaaa aaactttgaa attagaagca
    37441 ggagacattc aagttgcttt ttatcagcaa caagctgtaa ctattcagga taaattaaaa
    37501 gattatgcaa cgaataatta tatgagtgat tttaatgatt atgtttcttc aatgattaca
    37561 ggtcaaggca gtgcaggagg atatgtagtt ttatggccaa aagaaaaacc ttccaacatc
    37621 tttattatgg ataatccaga tttagaaaag gcaagagaag tactaagaat gaataaaaat
    37681 gggattgctt tttctaagaa aggatggcgg gggcctttta attcagcttg gacattagat
    37741 agtatattta atgccaattt tatacaaact ggattaatca aagcagatat ctttcaaaat
    37801 tcttttaaca agactggaga tgtattgaaa ttagttaatg gactactcca aatttggaac
    37861 aacaaaaaga aaataatgga gttaactaaa aaaggaatgg aattttggaa ttctaagggt
    37921 tcaattggaa cgattggaac aactgattct gttggtaatc cttttcctgg ggcttctact
    37981 ccaaccccta ttgaagataa ttctttagtt attcgtacaa atggagacgg caaatatatt
    38041 ttgatttctc ctaaagtagg aaaaggatta gttttattag gaaatggtaa agcaatttat
    38101 tttggagact tagatgtaca aggaaaactt acagttaaag gaaaagaaat aattcctgga
    38161 caaggtggtg gtccatcggg aggtggagaa tctactggtg ggtatcctag tgaattaaaa
    38221 acagatgcag aaaagagagc ttggagaat
//
LOCUS       DBBGSZ010000023        37564 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.023, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000023 DBBGSZ010000000
VERSION     DBBGSZ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 37564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37564
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.023"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(68..1210)
                     /locus_tag="ACIZE5_001647"
     CDS             complement(68..1210)
                     /locus_tag="ACIZE5_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6108776.1"
                     /translation="MATFFSYKLQNGEKYWGFETYLGKDPKTGKDIRTKRRRFKSKAE
                     AQTALNRLLVDFKEKQEFKINVTTFQELYELWIDNYRTRVKPSSVAVAQRFCKNHILP
                     AFGELRLDKISVSYCQKQVNEWHKTLKQYGFLRKTTAQIFKFGVAMEVCKDNPMSKTL
                     LPRKIEEEQPLKFYTKDQLQLFLQNTKENNSVKLYTFFRLLAYTGMRKSEALALQWED
                     IDYFNKTITIGKTIAQDEFNQVVLQVPKTKNSSRTIQLDDFTLKQLRIWQQEQMKIMI
                     LYGYNTNSPKQFLFTTNTNKLYYPQVVNDWLDWIYKKTPMEPQITPHGFRHTHCSLLF
                     ESGASIKEVQERLGHKDIKTTMNIYAHVTPQSVKKTGDRFAKFMGE"
     gene            complement(1261..2058)
                     /locus_tag="ACIZE5_001648"
     CDS             complement(1261..2058)
                     /locus_tag="ACIZE5_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6108777.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSDTFSLDKDYELLNPIIKNIFTKYYSKDFEIYLNEILANNINPLIEEYANQRH
                     SISKELFFKRANSKLQDKIRNGDFKYGEKERMIDSLKQLLDEMDLAYKDISKYSSVED
                     FFYKITKNQFETEKFISDLSKKYNFPYEKNSIIAKFLTDNHDKFKNN"
     gene            2260..2559
                     /locus_tag="ACIZE5_001649"
     CDS             2260..2559
                     /locus_tag="ACIZE5_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6108778.1"
                     /translation="MEAIKLMISEEQEEMFLKQFYQIATKAIEKAQENAGMTREYLNQ
                     KEMAEYLNVSENFLKNAVRNEGLPVVELGARKFYSKKAVNEFMFARMKRGENIGR"
     gene            2824..3699
                     /locus_tag="ACIZE5_001650"
     CDS             2824..3699
                     /locus_tag="ACIZE5_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108779.1"
                     /translation="MNAIVILAEITYWYRPKKIFNDDGQLLGYQKKFLEDILQKSYKQ
                     LSKKTGLSERAIKDAIVYLEKKGIIKRVFRNIYYEKRAVTLSNVMYIVLNVHKLIEIT
                     FPTLDCEKKEYMPKIRQRGIEKKRYVSLKKGRGMYKFVYTYTKTTSQNISKTTLVMEE
                     EDINIKRIYSKISVLYDANNEDGRKLFQVYHYLRNANVDTEDIRKIIEYLSENTQYLI
                     AECIIKQHEACFFQRKTEEGLYDYVTYFLNGLQKRYKSQFLENVEPIDQFKKAFEIKE
                     LPEITMHNWLKGEES"
     gene            3696..3914
                     /locus_tag="ACIZE5_001651"
     CDS             3696..3914
                     /locus_tag="ACIZE5_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108780.1"
                     /translation="MIKNRLIDQMWCLDQNTDTLELIESICFNTVVLDLRAENDNCVT
                     HIIINQKMAQQLSESLRKWAEGENYESN"
     gene            3901..6528
                     /locus_tag="ACIZE5_001652"
     CDS             3901..6528
                     /locus_tag="ACIZE5_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HGC6108781.1"
                     /translation="MKAIKEKIVSRKINWLALSVLVLMISVVFTSNIVEASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSVINTIVVGLMILSLMFVGYKMITGKGTIDLRSVGMNIVMSVALI
                     LLMPTMISSGIQFAKIFYNDATTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNKLTRKNFQQTDLTQVLTDKVIDKLEKENPAADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNAGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSTGFNRAKGSGN
                     GNGSDSGEGEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERAIK
                     PFKSMRDMANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPTRLSDR
                     KDGAKVENADRIMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMHGQAKS
                     AEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGANTDEKEALTKERIQEAKNSNTGL
                     EKLVKENLQNSTSSQGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNGQGTKTIDV
                     RENVQNSTSSQGFKSMDVRENVQNSTSSQGFKSMDVRENVQSSTSSQGFKTVDVRENV
                     QKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKPRRRFTYEDNE
                     LFRDTLNDPNPLFDNLLKK"
     gene            6543..6761
                     /locus_tag="ACIZE5_001653"
     CDS             6543..6761
                     /locus_tag="ACIZE5_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108782.1"
                     /translation="MKLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKHEIKNNLKYCYLEKSEEIIHELNGF"
     gene            8280..8594
                     /locus_tag="ACIZE5_001654"
     CDS             8280..8594
                     /locus_tag="ACIZE5_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108783.1"
                     /translation="MADENKVVPLETLVINKEEFEQLFLDFFVQYDRIYDFSSSLDLF
                     ELEAEIIENSREENGKIIISVEKFNELFSETFEIDTDYYQPQEVFQSFRNQIIRSGKT
                     VN"
     gene            complement(8647..9420)
                     /locus_tag="ACIZE5_001655"
     CDS             complement(8647..9420)
                     /locus_tag="ACIZE5_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108784.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSDTSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAQLYTEKVEQFFEAGANKDFSKISDYSDNFFNETQDEITNSTFMA
                     EDMYNMKLKKIKSYDYPLNLTLNKGILSFVLAGYVDYEYTADYLETPLQHDNNDINFR
                     FIYNSKSKTWLVDQLSTINTGFHELPKPDNETALVIKTF"
     gene            9525..9770
                     /locus_tag="ACIZE5_001656"
     CDS             9525..9770
                     /locus_tag="ACIZE5_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6108785.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRVRLEKGIGQTELIRDLQLRKIA
                     ITRETLVKIEGGRQHIKLDQLKAIKDILQVSYEDLLQ"
     gene            9926..10777
                     /locus_tag="ACIZE5_001657"
     CDS             9926..10777
                     /locus_tag="ACIZE5_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HGC6108786.1"
                     /translation="MYKAYELDFTNADLNAFSSSSQSYTHVVNQIDHNQKSINKRIEN
                     LFESENDLVDYYSKDSKILDADEIIKDWFPTIKADIFISHSHADEKLAIRFASWLFEN
                     FGLTAFIDSSVWGYSSDLLKKIDQKYCYKEQTKTYDYDKRNVTTSHVHMMLSTALNNM
                     IDSTECLFFLNTPNSISLSNEITNEQKFTYSPWLYSELTTASIVEKKNPRLESNPQMS
                     TEDVRSIIKHYSSQENLQIKYSLNLSELTYLRKADLKKWALDAVECTKGSNTLDILYK
                     NTIFTNL"
     gene            10810..11487
                     /locus_tag="ACIZE5_001658"
     CDS             10810..11487
                     /locus_tag="ACIZE5_001658"
                     /inference="COORDINATES: protein motif:HMM:NF024685.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HGC6108787.1"
                     /translation="MDKKVLIKRFSEAIEKGNAAIFAGAGLSMSQGYVSWPELLNDPA
                     TEIGLDSKKETDLVTLAQYYKNENGGSRGILNQILMDNFGEELEISENHRILASLPIE
                     TYWTTNYDHLIEKSIREAYKNPQVKKNYTQLATTNPNVDTIVYKMHGDIDDVSSTVIT
                     RDDYEKYDDSYALFKETLKGDLLTKTFLFLGFSFTDPNLERILSDIRWVLRENQRPHY
                     CIMRKIL"
     gene            11975..12940
                     /locus_tag="ACIZE5_001659"
     CDS             11975..12940
                     /locus_tag="ACIZE5_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6017 domain-containing protein"
                     /protein_id="HGC6108788.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKNLTLKAKGLLSQMLSLPEDWD
                     YTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDAKGKMADMVYTIYEQPVLENP
                     VLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLSKKEKIITDGQSTHSIPIPSP
                     TPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEYAYLIQDRSIDREQLDEIVDL
                     MLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRFVLDCLRENTTKVRNIKQYLR
                     AMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYSCGEGESL"
     gene            12962..13174
                     /locus_tag="ACIZE5_001660"
     CDS             12962..13174
                     /locus_tag="ACIZE5_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HGC6108789.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            13249..13725
                     /locus_tag="ACIZE5_001661"
     CDS             13249..13725
                     /locus_tag="ACIZE5_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HGC6108790.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            13722..15530
                     /locus_tag="ACIZE5_001662"
     CDS             13722..15530
                     /locus_tag="ACIZE5_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HGC6108791.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            15607..15822
                     /locus_tag="ACIZE5_001663"
     CDS             15607..15822
                     /locus_tag="ACIZE5_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family mobile element protein"
                     /protein_id="HGC6108792.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            15914..16777
                     /locus_tag="ACIZE5_001664"
     CDS             15914..16777
                     /locus_tag="ACIZE5_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB6/TrbL-like conjugal transfer protein,
                     CD1112 family"
                     /protein_id="HGC6108793.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            16814..17350
                     /locus_tag="ACIZE5_001665"
     CDS             16814..17350
                     /locus_tag="ACIZE5_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MT-A70 family methyltransferase"
                     /protein_id="HGC6108794.1"
                     /translation="MSTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVERL
                     ASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTRGN
                     AEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFARQK
                     TPGWDVWGNEVECDLILT"
     gene            17364..17786
                     /locus_tag="ACIZE5_001666"
     CDS             17364..17786
                     /locus_tag="ACIZE5_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HGC6108795.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            17716..20115
                     /locus_tag="ACIZE5_001667"
     CDS             17716..20115
                     /locus_tag="ACIZE5_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4-like conjugal transfer ATPase, CD1110
                     family"
                     /protein_id="HGC6108796.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            20147..22138
                     /locus_tag="ACIZE5_001668"
     CDS             20147..22138
                     /locus_tag="ACIZE5_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HGC6108797.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            22161..22412
                     /locus_tag="ACIZE5_001669"
     CDS             22161..22412
                     /locus_tag="ACIZE5_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HGC6108798.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            22402..23631
                     /locus_tag="ACIZE5_001670"
     CDS             22402..23631
                     /locus_tag="ACIZE5_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1107 family mobile element protein"
                     /protein_id="HGC6108799.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            23628..25709
                     /locus_tag="ACIZE5_001671"
     CDS             23628..25709
                     /locus_tag="ACIZE5_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HGC6108800.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            25858..29778
                     /locus_tag="ACIZE5_001672"
     CDS             25858..29778
                     /locus_tag="ACIZE5_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YodL domain-containing protein"
                     /protein_id="HGC6108801.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKTD
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLIERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            29779..30723
                     /locus_tag="ACIZE5_001673"
     CDS             29779..30723
                     /locus_tag="ACIZE5_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108802.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            30727..30930
                     /locus_tag="ACIZE5_001674"
     CDS             30727..30930
                     /locus_tag="ACIZE5_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HGC6108803.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(31230..31466)
                     /locus_tag="ACIZE5_001675"
     CDS             complement(31230..31466)
                     /locus_tag="ACIZE5_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6108804.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(31649..32020)
                     /locus_tag="ACIZE5_001676"
     CDS             complement(31649..32020)
                     /locus_tag="ACIZE5_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HGC6108805.1"
                     /translation="MSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECICVQSI
                     SYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAACSKRM
                     RRRKEAERQRKRYWKPTHLEL"
     gene            complement(32017..33345)
                     /locus_tag="ACIZE5_001677"
     CDS             complement(32017..33345)
                     /locus_tag="ACIZE5_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HGC6108806.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(33306..33635)
                     /gene="mobC"
                     /locus_tag="ACIZE5_001678"
     CDS             complement(33306..33635)
                     /gene="mobC"
                     /locus_tag="ACIZE5_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HGC6108807.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(33893..34263)
                     /locus_tag="ACIZE5_001679"
                     /pseudo
     CDS             complement(33893..34263)
                     /locus_tag="ACIZE5_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            34408..34593
                     /locus_tag="ACIZE5_001680"
     CDS             34408..34593
                     /locus_tag="ACIZE5_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGC6108808.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            34751..34918
                     /locus_tag="ACIZE5_001681"
     CDS             34751..34918
                     /locus_tag="ACIZE5_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108809.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            35536..36195
                     /gene="vanR-B"
                     /locus_tag="ACIZE5_001682"
     CDS             35536..36195
                     /gene="vanR-B"
                     /locus_tag="ACIZE5_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-B"
                     /protein_id="HGC6108810.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            36198..37541
                     /gene="vanS-B"
                     /locus_tag="ACIZE5_001683"
     CDS             36198..37541
                     /gene="vanS-B"
                     /locus_tag="ACIZE5_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-B"
                     /protein_id="HGC6108811.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPNFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
BASE COUNT        10642 a         8475 c         9208 g         9239 t
ORIGIN      
        1 taaagcgttt cgagcgtttt tttatttgta ttttaatggt tggctacgtt tttggctacg
       61 tttggaatta ttcgcccata aattttgcaa atcggtcacc agttttctta acagattgtg
      121 gtgtgacatg agcatagata ttcatggtag ttttaatatc tttatgacct aatcgttcct
      181 gtacttcttt tatcgacgca ccactttcaa acaataagct acagtgggta tgcctaaatc
      241 catgtggagt aatttgaggc tccatcggtg tctttttgta aatccagtct aaccaatcgt
      301 ttactacttg ggggtagtac aacttgtttg tgtttgtagt gaaaagaaac tgttttggtg
      361 aattcgtgtt atagccatat aagatcatta ttttcatttg ttcttgttgc caaatacgca
      421 gttgtttaag tgtaaaatca tcaagctgaa tcgttcttga tgaattttta gttttaggta
      481 cttgtagaac tacttgatta aactcgtctt gagcgatagt tttaccaatt gttattgttt
      541 tattgaaata gtctatatct tcccattgaa gcgccaatgc ttcgctttta cgcattcctg
      601 tataagctaa taaacggaaa aaagtgtaca gtttaactga attattttct ttagtattct
      661 gtaaaaacag ttgtaattga tctttcgtgt aaaacttcaa gggttgttct tcttcaattt
      721 ttcttggaag caatgtttta gacataggat tatccttaca gacttccatt gctactccaa
      781 atttaaatat ttgagcagtt gtttttctca agaaaccata ttgttttaat gttttgtgcc
      841 attcattcac ctgtttttgg caatagctaa cacttatttt atccaatcgt aattccccaa
      901 aagcaggtaa tatatggttt ttgcaaaaac gttgagcaac ggcaacagaa gacggtttta
      961 ctcttgttct gtagttatca atccataatt catacaactc ttgaaaagtt gtaacattga
     1021 ttttaaactc ttgtttttct ttaaagtcta caagtagtct attaagtgct gtttgcgcct
     1081 cagcttttga tttgaatctt ctacgctttg tacgtatatc ttttccagtc ttgggatctt
     1141 tccctaaata agtttcaaat ccccaatatt tttcgccatt ttgtaattta taactaaaaa
     1201 atgttgccat ttgattctct ccttacttca ttattgcagg tagagaagtt atttgaagaa
     1261 tcaattattt ttaaatttat cgtgattatc agttaaaaat tttgcgatta tactattttt
     1321 ctcatatggg aaattgtatt ttttactaag atctgaaata aatttttctg tttcaaattg
     1381 gtttttagta attttataaa agaaatcctc gacagatgaa tactttgaaa tatctttata
     1441 ggctaagtcc atttcgtcta atagctgttt taaagaatca atcattcttt ctttttcacc
     1501 gtatttgaaa tcaccatttc ttatcttgtc ttgaagttta ctgttggctc ttttgaaaaa
     1561 tagctcttta gagatagagt gtctttggtt agcgtactct tcaatcagag gattgatatt
     1621 attagcaagt atctcattta gataaatttc aaaatctttt gagtaatatt ttgtaaatat
     1681 attttttatt ataggattca ataactcata gtctttatct agcgaaaacg tatcactata
     1741 tctttcttga atgtctttaa agactttgtg aggtatttct gggaagtcct taatatatag
     1801 ctcataccct atatcgataa ggtatgaagt tatatattct tctaaagttc cccatttaat
     1861 ccagtcaatt gttgaattag tgatagttga taataatttc agcttttgtg gatttggtaa
     1921 attggtccca cgttcccagt tggatatggt cgcacgtggt gaattatcta ttttccttcc
     1981 aagttcttcc atagtaaaac cacatgaaag gcgtaattgt ttgattcgtt ttcctgcttc
     2041 tgaaggattt ggcttcatct tttttctcct ttttattttt aaagatagta tatcatattt
     2101 ataaaataaa agtatttaaa agtatttact ttttatctgg agtatgatac tttattctta
     2161 taaatacaaa taaatacatt tttttacgca atttgtattt atttgtactt ataaaggtag
     2221 aggagttata gaataattaa ttaaaaagga gaggtttttg tggaagcaat aaaattaatg
     2281 atttcagaag aacaggagga aatgtttcta aagcagtttt atcaaattgc tacaaaagct
     2341 attgaaaagg ctcaagaaaa tgcggggatg acaagggaat atctcaatca aaaagaaatg
     2401 gcggaatact taaatgtgag tgaaaacttt ttaaaaaatg ctgtgagaaa tgagggattg
     2461 cccgtagttg aattaggggc aagaaaattt tattcgaaaa aggcagttaa tgagtttatg
     2521 tttgctcgaa tgaaaagagg ggaaaatatt ggaagatgat gaagtagaaa ttataaaaaa
     2581 atgctttaaa aaaagaaaaa aagtgttccc aaaagtttgc agactggggg aacactcaat
     2641 aataaagtgc tgagaaaact ttatttatag ctattatatc aaaaaagaag gtgaaaaggt
     2701 gttttcttct ggaaatgttg tagttgacaa acttagagaa ataaattttg acggaaatgt
     2761 aatccacaca catggtacga tcaattaaga aaaaaaacga aaaaaggtgt tgagaagccc
     2821 tatttgaatg caatagttat cttagcagaa attacctatt ggtatagacc taaaaaaatt
     2881 tttaacgatg atggtcagct acttggttat caaaaaaagt ttcttgaaga tattttgcaa
     2941 aaatcatata agcaattaag caaaaaaaca ggattatcag aacgagctat aaaagatgca
     3001 attgtgtact tagagaaaaa ggggattatc aaaagggttt ttagaaatat ttattatgag
     3061 aaaagagcag ttacattatc aaatgttatg tacattgttt taaatgtaca taaattgata
     3121 gaaattactt ttcctacttt ggattgcgaa aaaaaggagt atatgccgaa aattcgtcag
     3181 aggggtatcg aaaaaaagag atatgtctct ttaaaaaaag gtagaggtat gtacaaattt
     3241 gtatatacgt atacaaagac tacttcacag aacatatcaa agactactct cgttatggaa
     3301 gaagaggata ttaatataaa gaggatttac agtaagatta gtgttcttta tgacgcaaat
     3361 aacgaagatg gtcgaaaatt atttcaagtg tatcactatt tgagaaacgc taatgtagat
     3421 acagaagata tcagaaaaat cattgaatat ttatctgaaa atactcagta tcttattgct
     3481 gagtgtatta taaaacaaca tgaagcatgc ttttttcaaa gaaaaactga agaagggtta
     3541 tacgattatg taacatattt tttgaatgga cttcagaaaa gatataaaag tcaattttta
     3601 gaaaatgtag agcctataga tcagttcaaa aaagctttcg aaatcaaaga gttacctgaa
     3661 attactatgc ataattggtt gaaaggagaa gaatcatgat taaaaatcgc ttaatagatc
     3721 aaatgtggtg tcttgatcaa aatacagata ctctcgaatt aatcgagagt atctgcttca
     3781 acacagtagt tctcgattta agagctgaaa atgacaattg tgtaactcat atcataatta
     3841 atcaaaaaat ggctcagcag ctctctgaga gcctaagaaa atgggctgaa ggagaaaact
     3901 atgaaagcaa ttaaagaaaa aatcgttagt agaaaaataa actggttagc actcagtgta
     3961 cttgttttaa tgattagcgt tgtttttaca agtaatattg ttgaagctag cattttcaat
     4021 tggtttgatg acacaaaaag tcaaacagag tttttgaata attctcttta tagaccttac
     4081 ctaaaaaaat acaatggaga tttccttagt cagttcggga tttggcttgg atgggctgtg
     4141 gtaaaaggca tgtttactgt gactgattcg attcaaaata tgattccaga tgtgttggat
     4201 ttgttcaatt tcattgaaag tacagggcta aataatgttt atcaatcagt cataaataca
     4261 attgtcgttg gattaatgat cctttcattg atgtttgttg gctacaagat gattactgga
     4321 aaaggaacaa tagatttaag atctgttgga atgaatatag tgatgtctgt agcgttaatt
     4381 cttttaatgc caacaatgat ttctagcggt attcaatttg ccaaaatatt ttacaatgat
     4441 gctactacga ttacaaattc agatgacgga gtcgcttggt cattgataaa acaaggagta
     4501 acagatctgg catatattaa taaaacagat caatactcaa gcattgataa aacggaggat
     4561 cgaaataagt taacacgaaa aaattttcaa cagacagatt taacacaagt gttgacggat
     4621 aaagtgattg ataaattgga aaaagaaaat ccagctgcgg ataatcttcg ctatgaatta
     4681 gttgaaaatt ctaataatga atttgttgcc acaaagtttt ctgataactt cttatcaaca
     4741 ttttctgata gcttgaaatc aggttattat cgatatcaag caaatctttg ggggatttcg
     4801 attgggttga cagcgttggc aatcgcctat gtgttcagcg cgtttgtgat cattacagca
     4861 atattagaac ttgcatttaa acgtgtgtta ggtgttcttg tttttgcgac agatattgaa
     4921 acaggacaac gttcaaaagt tgttttatcc gatattttac aatgttactt aacagttgga
     4981 tttcaagggt ttggactatc tatgtttgct atgtttatca attttttaaa tgctggacaa
     5041 ggtatctcca caaatatttt tataaaaaca attgcttata tctgtgctgt gtttgtgctg
     5101 ataaaaggca gtggaacagt catgagatac tttggtgttg atattggact caaagaaggc
     5161 tatgggcaac ttgcttctgc ttttggtatg ggcgcaatgc tgtttagaaa aggatcaact
     5221 ggatttaatc gtgctaaagg aagcggaaat ggaaatggat cagacagtgg agaaggagaa
     5281 gatcgaaaac cagaaaagaa tttcggcgaa actctatcaa aaaaagctgg caaaactgga
     5341 agagctttgg gatatgccca tgaacgtgga ttatcaggtt tagcttcaga tggagctaca
     5401 atggctagtg aaagagcaat aaaaccattt aagagtatgc gtgatatggc taatgatacc
     5461 aagaataagt tcaaagaagg tttagatgat ggtacagtgt ccgctattaa taaaaatagc
     5521 aaacctatgt tagctaaaaa taaagaagat gaaactggaa aatatgctga ttccatgcca
     5581 acacgtcttt cggatagaaa agatggtgct aaggttgaaa atgccgatag aattatgtct
     5641 agttctgaac gtatgcgtga agcaatgaaa aataatgctg aatcgaataa taatcctgta
     5701 agtgcaattc agcaaaaagt tcaacaagat attgaagaac gtaaaaatgc tatgcacggt
     5761 caagctaagt ctgctgaaga attaattaat cagaagcgac aagaagctaa atacacgcct
     5821 gaagcaatga atcgtgagga aatgttaagg aaacgtgtag aagggcgtac aggagctaat
     5881 acggacgaaa aagaagcgtt gaccaaagaa agaatccaag aagctaaaaa ctcaaatacc
     5941 ggattagaaa aattggtcaa agaaaatcta caaaattcta caagtagtca aggtggccga
     6001 tcagtagatg tccgagaaaa tattcaaggt tcattgaatg gtcatgtcgg acggaatgtt
     6061 gatgtaagag agaatttaca aagctcttca aatggtcaag gtactaagac aattgatgtt
     6121 cgagaaaatg tacaaaattc tacaagtagt caagggttta aatcaatgga tgtaagagag
     6181 aatgtacaaa attctacaag tagtcaaggg tttaaatcaa tggatgtaag agagaatgta
     6241 caaagttcta caagtagtca aggattcaaa acagtagatg ttcgggagaa cgttcaaaaa
     6301 gatagtggag aaatgaaaga aaaaacacaa aaaatcaata tcgttgaaga cagaaagtca
     6361 gcgaaaaaat ttgattcaaa tcatgaaaca gtgattattg atagtgaaat ccgtgaaaat
     6421 gataagggat caaaaccaag acgaagattt acctatgaag acaacgagtt attcagagat
     6481 acacttaatg atcctaatcc gcttttcgat aatctattaa aaaaataaaa gggggaattg
     6541 tcatgaaatt aattctaaag attagtacgc atgatttctt agaacttgac gaattatgtg
     6601 aatcagtaaa gaacgcaaca aatgaaaaaa tcacggtcac taattatatt gaactgatga
     6661 ttcaagaaga attaaagatg aaacatgaga taaaaaacaa cttgaaatat tgttatctag
     6721 aaaaaagtga agagataatc catgaattaa atggctttta aaaattgtat ttgacatgaa
     6781 tttacgacaa ggaattagtg gggattaagc gattattctc ttccacttta gagaaataat
     6841 gggttaaaaa gccagaatac gtagagcaat attgacaacc tataaaggag ctattgttga
     6901 aaattgaagt aacaaaaaga taaagagagg tttacatcta tcagattaaa agtgatagta
     6961 cacccatgaa acctgcaaaa gagttgaacc taatgtatat cggtttaact ctttttattt
     7021 gcaaattaaa aaaatatcac cgaagtgacg aatgaaacta tgaccaaatt aagcaagaaa
     7081 atatatcttg caaataaagt agtataaaaa gatattgata aagccaatca aaactttgaa
     7141 tttcaaacgt tagataatca aacagataca aaaaatgaaa tcagttctac gcgtacgatt
     7201 attaaaaata ataaattttc actagaagaa aatggaaata aaatcaaata attagtaaga
     7261 aaaaacaaag caattagaaa agcctgcaag caaatttgag taatcgagat ccaatttttt
     7321 taaggaagtt taacaaaaat atgtaattct attatcacta ttaaagagaa agttggagcg
     7381 gaatataaag aaaagagaaa agtaattaaa cgcaaaaaaa tgtagaactt aaaaaatata
     7441 aagaggaaca accgttaaaa ttaggaatga tgttgtgtaa acattataat tgctatgata
     7501 taaatgaagt gttaaagaaa gcaaatttaa accaattttg tgaacagaaa agccttagtc
     7561 actatgacca aaactacgga cgaaactatg accaaaagta ggtactaaat tatgaccgaa
     7621 aataggtcca aaatggattt ttttatgata tcaaaaatta tgaaatgatt ttgaaagaaa
     7681 accagttggc acagccaact tagccacctt cctgtaggaa ggtgctatca gttttccctt
     7741 atgctctttt ctttcttttt tgtttcatat gtcaaatgcc attttgaaat gtaccatctt
     7801 aagaaattta tccttaaaaa caattgcgtt attggataaa aagatgctac attatcttaa
     7861 aaaaggaatc aaatatgatg aatttagtgg ctagcatatc gtgtgattaa gatactttat
     7921 agtgtaagtt gaaggagaaa aaatatttaa aatatacttc ccatttcagt gggaagtaaa
     7981 attaatcttg ttgtttctac tagtaatgta tctttttgga aactatgtaa cgatgtaaac
     8041 aagatttttt tcagaagaaa aaacgataaa agttgtgata aacgatttaa aaaataggag
     8101 aaaatatatc aagcgcatgg tatgaaacgc acatttaaaa agattcgact aactaaaaaa
     8161 ataagtttac aaagcattgt tgtgtattac aagtgatcta tacactgaaa aatgatagag
     8221 aaaatctgat acgtccgcaa caatggacaa ttgaaaatga aagtgaggaa attggaagaa
     8281 tggctgatga aaataaagtt gttccgcttg aaacactagt gataaataag gaagagtttg
     8341 agcaactttt tcttgatttt tttgttcaat atgacaggat ttatgatttt agttcgtcac
     8401 tagatttatt tgaattagag gcagaaataa tagaaaacag tcgagaggag aatggtaaaa
     8461 tcatcatttc agtagaaaaa ttcaatgaat tattctcaga aacatttgaa atagatacag
     8521 attattatca accacaagaa gttttccaat catttagaaa tcagattatt cgctcaggta
     8581 agaccgtaaa ctgaaaaaca ataaaagaaa cgttgaaaga ataattattc cttcaacgtt
     8641 tcttttttag aatgttttaa tgaccaaagc agtttcattg tcaggcttag gtaattcatg
     8701 aaatcccgta tttatagtgc tcaattgatc aactaaccat gttttacttt ttgaattgta
     8761 gataaatcta aaattaatat cgttattatc gtgttgaagg ggcgtctcca aataatctgc
     8821 tgtatattca tagtcaacgt aacctgctaa tacaaaagag agtatccctt tatttaatgt
     8881 tagatttaat ggataatcat acgactttat ttttttcaac ttcatattgt acatatcttc
     8941 agccataaaa gttgagttcg tgatttcatc ttgggtctca ttaaaaaagt tatccgaata
     9001 atcgcttatt tttgaaaagt ctttattggc accagcctca aaaaattgtt caactttttc
     9061 agtataaagt tgtgctaacg ctcctttttc aatattaact ttaatatttt catgtctatc
     9121 aatttgtgtg ctgttcagta agggaagatc agcttttagt tttatatcgt cttgatttct
     9181 ttcaatttca attggcaaaa tcttttcagt agattcagtt tctgataaag gaacatctag
     9241 ttttttatca tgataataag cttcaaatcc atctggaacc ggaaaaaaat gtattgggta
     9301 attcttttct gaggttgttg tactagtttc cgtacttgta gaacttgtgt cagaagtggt
     9361 acacccgctt atagttccga tgagtaaagc gcaagttaga atgattgcaa atttcttcaa
     9421 aaaaattcct ccttaaaatt gaatatggac taatactagt cccattgtag cataccgaat
     9481 ctttaagatt aataagaaaa aggactaatt ttagtccaaa aggtgtgcta ttcttgaaag
     9541 aggaaaaaat tattgataaa gaaaatgtaa tcggtagcaa tattagacga gtccgattag
     9601 aaaaaggaat tggtcaaacc gagctgatta gagacctaca gcttcgtaaa attgctataa
     9661 ctagggaaac gttggttaag attgaaggtg gccgccaaca cattaagttg gatcaattga
     9721 aagccatcaa agatattcta caggtgtctt atgaagattt gcttcaatga ctacttgtag
     9781 tcatttcgtt tgaaattatt atgttacacc cttatgtgtc acgaagaaat actggtataa
     9841 taatgaatgg gatatgtaac gatagggtat actgttatgt tgcctaataa attgtggatc
     9901 aaaatacaag aatggaggga tatccttgta taaggcatat gaattggatt ttacaaatgc
     9961 tgacttaaat gcattctcct caagctcgca atcatataca catgtagtaa atcaaataga
    10021 tcacaaccaa aaatctatta acaagagaat agaaaatcta tttgaaagtg aaaatgattt
    10081 agttgattat tattctaagg acagcaaaat tctagatgca gacgaaatta ttaaagattg
    10141 gtttccaact ataaaagcag atatttttat atctcactct catgctgatg aaaaattagc
    10201 tatacgtttt gcatcatggc tatttgaaaa ttttggtctt actgcattta ttgattcttc
    10261 ggtttgggga tacagttctg atttattaaa aaaaatagac caaaaatatt gctataagga
    10321 acaaacaaaa acatatgatt atgataaaag aaatgtaaca actagtcatg ttcatatgat
    10381 gctttctaca gctttaaata atatgattga tagtacagaa tgtctgtttt ttcttaatac
    10441 acctaattca attagtttga gcaatgaaat cactaatgaa cagaaattta cgtattcgcc
    10501 atggctatat agcgaactga cgacagcttc aatagtggaa aaaaagaatc cacgattgga
    10561 aagtaatcct caaatgagca ccgaggatgt tagaagcatt ataaagcact attcttcgca
    10621 agaaaatctg caaataaaat attctttaaa tttaagtgaa ttaacttatt tacgaaaagc
    10681 tgatttgaaa aaatgggctt tagatgctgt ggaatgcact aaaggaagta atacattaga
    10741 tattttatat aaaaacacca ttttcactaa tctctaatca atttactgaa tcgaaaggaa
    10801 ccgggtagaa tggataagaa agttttaata aagaggttct ctgaagctat tgaaaaagga
    10861 aatgcagcaa tatttgcagg tgcaggatta tcgatgtcac aaggatatgt aagttggccg
    10921 gaactactta atgatcctgc aacagaaatc gggttggatt ctaaaaaaga aacagactta
    10981 gttactctgg ctcaatatta taaaaatgaa aatggtggat caagaggaat tttgaatcag
    11041 atacttatgg ataattttgg tgaagaatta gaaatatctg aaaatcatcg aatactagca
    11101 agtttaccta ttgaaactta ttggacaact aattatgatc atctaataga aaaatcaatc
    11161 cgagaagctt ataaaaaccc tcaggttaag aaaaattata ctcagttagc aacaactaat
    11221 ccaaatgtgg atacaattgt ttataaaatg catggtgata tagatgatgt cagttcgaca
    11281 gtaataacaa gagatgatta tgaaaaatat gatgattcgt acgcgttatt taaagaaact
    11341 ttaaaaggag atttgttaac aaaaactttt ctctttttag gatttagttt tacagaccct
    11401 aatttagaaa gaattttatc agatataaga tgggttttga gagaaaacca aagacctcat
    11461 tattgtataa tgagaaaaat attatagaaa aaattttagg ttatcgctga aagccccgga
    11521 aatacgggca tttcgcagga tatgagaact caatttacta ccaatttact actttcggat
    11581 tgagccgcat atatgctgaa ccatactgct aatacccgcc accccaaata cggcacatca
    11641 taaattgaat acgacaccgt aaacgcggcg ttcctctttc ccgtcatggg agaacaggac
    11701 gccgcttttt tatgcccaaa tagagaaagg aggcgacgcc atgctattta cttccggccc
    11761 tgaccgggcg tttgaacggc tgatgcagga aaagcccggt ttcgatcact acgacggcgg
    11821 cggggcggac gcgccggagg attgcggcac ctgccgattt taccgcccgg attggaaata
    11881 tcaattctgc cagtttgcag agtgtcccta tcagccgggc aagctgaccg actatgcagc
    11941 ggtcaaattc acagtgaaag gagcgaacaa cgctatggca gttttccgtg tggaaaagaa
    12001 caaaggctat acggtgatgt caaatcacca cctgcggaat aagaacctga ccttaaaggc
    12061 caagggcctg ctgtcgcaga tgttgtcctt gccggaggat tgggactata ccctaaaagg
    12121 actgtcctat atcaaccggg aaagcatcga cgcgatcagg acagcggtat gggagcttga
    12181 aaaagctgga tatatccggc gtgagcaggg ccgtgacgca aaaggcaaaa tggccgatat
    12241 ggtctatacc atctacgaac agccggtatt ggaaaacccg gtattggaaa atccaacatc
    12301 ggataacccg gtgttggaaa atccgacatc ggataatccg gcgtcggaaa atccaacgca
    12361 attaaataaa gaagtacaaa gaactgactt atcaaaaaaa gaaaaaataa ttacagatgg
    12421 acaaagtacc cattccattc ctatcccatc cccgacccct gcccctatgg agggcgaggc
    12481 agcggctacg ccgccggaac ggaaaaggac aggaaaggat gaggctgtac ggatttatcg
    12541 ggaaatcatt ttggagaaca tcgagtatgc ctatctcatt caggacagga gcattgaccg
    12601 tgaacagctt gacgaaatcg tagacctgat gctggaaacc gtctgcaccg cccgaaagac
    12661 aatccgtgtc gccggggacg actaccctgc cgagctggtg aaatccaagt acatgaagct
    12721 gaccggcgaa catatccgct ttgtccttga ctgtctgcgg gagaacacaa cgaaagtccg
    12781 caatatcaaa caatacctgc gggctatgct gttcaacgcc cccagcacca tttccaacta
    12841 ctacacggcc cttgtcgcgc acgacatggc acagcccgat tggggaaagc ctaaatccgg
    12901 cctgccggac tattcctgcg gcgagggcga aagcctgtaa cgagaaaagg aggacgaccc
    12961 tatgaagcag ggcgcattga tttttgacga gcgaacagac cgttacgaca tccgctttga
    13021 tctggccgac tattacggcg gcctgcattg cggggagtgt ttcgacgtga tgatcggcgg
    13081 caaatggagg cccacccgca ttgaaatggc cgaaaactgg tatcttgtcg gcatccgggc
    13141 cgacgacctt tccggcctgc gggtgcggat ttgacctata tctacctgcg gcgtctggtg
    13201 gttccgcctt agacgccgct tttgactttc tgacaaggag ggatgcgatt gcaggaagaa
    13261 gttactcaaa agaccattgc cctgtccatg aaaacgggca agctcacggc tcaagtgctg
    13321 caagcggcgc tgaaaaagta cctgcaacac cgggccaagg gcaaaaacac gctgcaccac
    13381 ggccagcaga gcctaaagca gcttaaaaag catggggctg atctctccaa cattgagatc
    13441 accgaggcca acattggagc gttcaagcca tgcgccaaga aatacggcgt ggattttacc
    13501 ttacgaaaag ataagaccac ccagccgccc cactacgttg tgattttcaa ggccaaggat
    13561 gcagataacc ttgatctggc gtttcgggag tttaccgcca agacgctttc caaggagcag
    13621 cggccctcta tccgcaaggt tttgtccgct gtgaagcaaa aggcggcggc ccagaccaag
    13681 cagcgggcca aggagaaaat caaggaaagg gggctggaac tgtgaagcct gacgtaaaga
    13741 aattgctgat cctgaacctc ccgtatctga tttttgtgta cctgtttgcg aaatgcgggg
    13801 aggcgtaccg gctggccgct ggtgctgacc tgtcggggaa gctcctgcat tttgcggatg
    13861 gttttgcggc ggcttttgcc aacccgctgc caagcctgca cctgtttgac ctgtgtatcg
    13921 gtatcgccgg tgccgtgatc gtgcggctgg tggtgtactg caagagcaag aacgtgaaga
    13981 aataccgcaa aggcatggag tatggcagcg cccgctgggg gacggccaaa gacatagcgc
    14041 cttacatcga ccccaagttt gaaaataata tcctgctcac ccaaacggaa cggcttacca
    14101 tgaccggcag gcccaaagac cccaagacag cgcggaataa aaacgtgctg gtgatcggtg
    14161 gcagcggttc agggaaaacg agatttttcg tgaaacccaa cctgatgcaa tgctttccga
    14221 ccacggacta tccgacttcg tttgtggtga cagatccgaa aggcactttg gttctggaaa
    14281 ccggcaggat gttccagcag gcgggctacc gcattaaaat cctgaatacc attaactttt
    14341 ccaagtccat gaagtacaac ccctttgtct acatccattc ggaaaaggac gtgctaaagc
    14401 tggtaaatac cctgatttcc aacaccaagg gcgaggggga aaagtcagcg gaggattttt
    14461 gggtgaagtc ggaacggttg ttttattcgg ccctgatcgg ctatatctgg tacgaggccc
    14521 cagcggagga aatgaacttc tcaacgctgc tggaaatgat aaacgccagt gaagcccgcg
    14581 aggacgaccc ggagtttcaa agccccgtcg atctcatgtt tgagcgtttg gagcagaaag
    14641 accccgacca ttttgcggtg cgccagtaca agaaattcct gctgtccgca ggcaagaccc
    14701 gttcttccat cctgatttca tgcggtgcca gacttgcgcc ctttgacatc cgggaggtac
    14761 gcgagctgat ggaggacgac gaaatggagc tggacaccat cggggacgaa aagacggtgc
    14821 tgtatctcat tatgagcgat acggacacga cctttaattt cattctggct atgctccaaa
    14881 gccagctaat caacctgctt tgtgaccggg ctgatgatgt gtacggcggg cggctgcctg
    14941 tccatgtacg cctgattttg gatgaatttg ccaacattgg ccaaataccc aatttcgata
    15001 aactcattgc caccattcga agccgtgaaa tatcggcctc tattattttg cagagccagt
    15061 cgcagctaaa agcgatttac aaggacgccg ccgagatcat ttcggataac tgcgatagtg
    15121 tgcttttcct tagtgggcgc ggcaaaaatg ccaaggagat ttccgatgcg ctggggaaag
    15181 aaacgattga cagtttcaac accagcgaga accggggaag ccaaacgtcc cacggattga
    15241 actatcaaaa attaggaaag gagttgatgt cccaagacga aattgccgtg atggacggcg
    15301 gcaagtgtat cttgcagcta cggggtgtgc gcccgttttt atcggagaaa ttcgatatta
    15361 ccaagcatcc ccggtacaaa taccttgccg acgccgacaa gaagaatacc tttgacgtgg
    15421 acagattttt gactatcacg cgccggaaac ggcagcaagt ggtaacgcag gatgaagtat
    15481 tcgacctgta tgaaatcgac ctgtcggacg aggacgccgc cgctgaataa acagcggctt
    15541 ttttcattcc aacaacaaaa tcaaaaaatc attatgagcc ggaaaccggc agaaagaggt
    15601 aaatttatgg cattttttaa ttccgcagtt actactttgc agactatcgt gatcggactg
    15661 ggcggcgctc tgtgcgtatg gggcggcatc aatctgttgg agggatacgg gcaggacaat
    15721 ccgggggcaa aatcgcaggg tgtcaagcag cttgtcgctg gcggcggcgt ggccctgatc
    15781 ggtgtcactc tggttcccct gctgtccggg ctgctgggct gatcctggcc tttgtccctg
    15841 tccaaaccct taactaatcg cctccgcgtc ctcccggcca gaccgggagg gcgcgggaaa
    15901 ggaggtgcta cccgtgatta gtgaaatcat tgaagaatgg ataaaaggca tcctcatgga
    15961 cggtatcacg ggcaacctgt ccgggctgtt cgatacggta aatgccaaag tcggagaaat
    16021 cgccgccgac gtgggacgaa ccccgcaggc atggaacagc ggtattttca atatgctgca
    16081 cagcctgtcg gaaaccgtga tcgtccccat agccggggcc atactcgccc ttgtcatgtg
    16141 ctatgagctt atccagatga taacggaaaa gaacaatatg cacgactttg acagctccat
    16201 gttcttccgc tggatattca aatccgcgtt tgcaatcctg atcgtaacga acacatggaa
    16261 catcgtcatg ggcgtattcg acgccaccca aagcgtcgtc aatcaaagcg ccggtgtgat
    16321 tatcgggcag acatccattg attttaacac cctgatacca gaccttgaaa gccaattgga
    16381 ggctatgagc gtgggcgctc ttttggggct gtggttccaa acccttgttg tgggcctcac
    16441 catgaatatc ctttccatct gcattttcct tgtgacctat ggccgcatgg tggaaatcta
    16501 tgttgtcacg tcgctggggc ctatccccct tgccacaatg ggcaacgcgg aatggcgcgg
    16561 catgggccaa gggtatctga aatccctgct ggcgctgggc ttccaagcct ttttaatcat
    16621 ggttgtggtg ggtatctacg cggtgctgat acagaatatc ggttccgctt ccgacatatc
    16681 cggcgcaatc tggggctgta tgggctatac ggtgctgctg tgcttctgcc tgttcaagac
    16741 cggcagtata tcaaaggccg tattcggggc gcattgatcc caaaatccaa gcatacacag
    16801 gaggaacttg tttatttcaa cgtacaacat catttacgct gacccgccgt ggcggtatga
    16861 ctgcaaaaac gtacagggcg cagcggaaaa tcactattcc accatgagca ttgacgagct
    16921 gtgcgccctg ccggtggaac ggctggcgtc caaagactgc ctgctgtttt tgtgggccac
    16981 attccccatg ctgccggaag ctctgcggtt aatcaaagcg tggggctttt cattcaagac
    17041 cgtggctttt gtatggctga aacagaaccg taaaagcctt acatggtttt acgggctggg
    17101 ccgctggaca aggggaaacg cggaaatctg cctgctggca acacacggca agccgaagcg
    17161 tcgttctgcc tctgtccatc agtttattat cagcccgatt gaacaacaca gcaaaaagcc
    17221 ggatgtgacc cgtgaaaaaa tcgtagagct ggcgggcgat ttgccccgcg tggagctgtt
    17281 tgccagacag aaaacccccg gctgggacgt gtgggggaac gaggtggaat gtgaccttat
    17341 cctgacgtga aaggaggtgc caaatggctt atgtaaccgt ccccaaggac ttaacccatg
    17401 tgaaaagcaa ggttgtgttt gggcttacca aacggcaact gatctgtttt tccggggcgc
    17461 tggtgatcgg cgtcccctta tattttctca cccgtgacta tcttaccaac agcgcggcgg
    17521 ccctgctcat ggtatttgcc atgctgccgg gctttttgct tgccatgtac gagcgtcacg
    17581 gccagcccct tgaagtggtg attatgcaga tcatccagtg ctgcttcatc cagccaaagg
    17641 agcgtcccta tcagaccgac aacacctaca ccgcccttgt gcggcaatac cagatggaac
    17701 aggaggtaaa ggccattgtc caaaaaggaa atcccaagag aaaccgaaaa aacaaagctg
    17761 acccgcgccc agcgaaaaga aattgacgcg gtaatccgta aatataaggg cgacggcagg
    17821 ccccacacgg cgcagcagag catcccctac gaggtcatgt acccggacgg cgtgtgccgg
    17881 gtatcgcccg gcgtcttttc caagtgcatt gagtttgcgg acatcagcta tcagcttgcc
    17941 cagccggaca cgcagacggc tatctttgaa aaactgtgcg acctgtataa ctatgtggac
    18001 gcctccattc atatccagtt ttctttcctc aatcggaaag ttgacccggt gcagtacgcc
    18061 aagagctttg agatcgcgcc gcagggggac gacttcgacg acatccgggc cgagtacacc
    18121 ggcattctgc aaaagcagct tgcaaacggc aacaacggca tggtaaagac caaatacctg
    18181 acattcacca tcgaggccga aagcgtgaaa gcggcgcgag ccagattgaa gcgcatcggc
    18241 tttgacctgt taggctattt caagagcatg ggggccgtag cccatgtgat ggacggctgg
    18301 gaacggctga acctgctgca tggcgtgtac cacccggacg gcgagatatt caattttgac
    18361 tggaagtggc tggccccgtc cggcctctcc accaaggatt ttattgcccc gtcctccctg
    18421 tgcttcggca atgcaaagac attcggcatg ggcggcaaat acggcgcggt aagtttcctg
    18481 caaatcctgt ccccggagct gtcggacgat atgctggccg acttcctcaa tacggaaagc
    18541 ggtgttttag tcaatctcca tgtgcaggcc attgaacaga ccaaggcgat caagaccatc
    18601 aagcgcaaaa ttaccgacct tgacgctatg aagattgcgg agcagaaaaa ggccgtccgc
    18661 agcggttacg atatggacat tcttcccagc gaccttgcca cctacggcga ggacgccaag
    18721 aagctgctga caaagttgca gacccgcaat gaacggctgt tccagttgac gttccttgtc
    18781 ctcaacgtgg ccgacaccaa gcaaaagctg aataacgacg tgttccaagc cgcaggcgtg
    18841 gcccaaaagc ataactgtcc ccttgtccgg ctggactacc agcaggaaca gggccttgca
    18901 agcagcctgc cgctgggcgt caatcagatc aagatacagc gcagccttac gacttccagc
    18961 gtggccgtgt tcgtcccctt tgtgacgcag gagctttttc agggcggcgc ggccatgtat
    19021 tacggcatca acgccaagtc ccgcaacatg attatgctgg acaggaagca ggcccgttgc
    19081 cccaatgcct tgaagctcgg cacccccggc agcggcaaat ccatgagctg taaatccgag
    19141 atcgtcagtg tgttcttaac gacgcctgac gatattttta tttcagaccc ggaggccgaa
    19201 tattaccccc ttgtcaaacg gctccacgga caggtaatcc ggctgtcgcc taccagcaag
    19261 gactttgtga acccgctgga catcaacctg aattattcgg aggacgataa cccgctggcc
    19321 ctgaaatccg actttgtgct gtcgttctgt gagcttgtca tgggcggcaa gaacgggctg
    19381 gaagccattg aaaagaccgt gatagaccgg gctgtgcgcg tgatctaccg gccctatctg
    19441 gcagaccccc gcccggagaa tatgccgatc ctgtccgacc tccacaaagc gttgttagat
    19501 cagcatgtcc cggaggctga ccgggtggcg caggcccttg acctgtatgt gtccggctcc
    19561 ctgaacgtat ttaaccaccg taccaacgtg gacatcggca accggcttgt gtcctttgac
    19621 attaaggagc tgggcaagca gctcaaaaag ctggggatgc tcattgtcca agaccagata
    19681 tgggggcgcg tcacggccaa ccgaagccaa ggaaaggcca catggtattt tgccgacgag
    19741 ttccatttgc ttttgaaaga ggaacagacg gcggcctatt ctgcggagat ttggaagcgg
    19801 tttaggaaat ggggcggcat tccaacaggt gccacccaga acgtcaaaga cctgctttcc
    19861 tccccggaaa ttgaaaatat ccttgaaaac agcgacttca ttacgctgct caatcaggcg
    19921 tccggggata gaaaaatcct tgcggaacgc ttgaatttgt ccaccgaaca gcagaagtac
    19981 atcgacaatt ccgaacccgg cgagggcctt ttgatctttg aaaacgtggt gctgcccttt
    20041 accaacccca tcccgcacaa cacccagctt tacaagatta tgacgacccg cttaaacgag
    20101 gtggcgggag tatgacccgg cgacgccaca aaggaggtga accaccatga aagagctgaa
    20161 agccaaggcg aaagtgacgc aggccatgac ccgcgacggg ctgacgctgg aaaatcaggc
    20221 caccggcgag gtggagaaca tttccagccg ggaggccgaa caggatttgt ccgcgccggg
    20281 gccgggcggc accgccgata agctgctgga acgggccgac gccatccatg acggccataa
    20341 ggccaagaaa gccgcgaagc aggccggggc tgtggccgcc gagggggacg ctgccctgca
    20401 ccggccatcc gcccggctcc aactgtcgga ggaagaacgg gccgacccgg atttacagcc
    20461 ctatatccga aaatcggaca aacgggccga taagctggat aaggcccgcg ccgccatccc
    20521 caagaagcgc gtcccggtca aggaaaccgt ctttgacgag gcaagcggca aagcaaagac
    20581 cgtcctgcac tttgacaaac aggacaaggg gcctccctcc ctgaaaccca atccggcagg
    20641 ccgtcctgtt tccgaggttt ttctattcgg ccacgggaaa atccatgaag tcgagcatga
    20701 aaacgtgggt gtggagggcg gccataaggg ggaggaactt gccgagcggc aggccggaaa
    20761 agccatccgc agcaccatcc ggcaccacag gctgaaaccc tactgggacg cggaaaaggc
    20821 cgagcgcagg ctattgtctg ccaacgcgga gtatttctac cagaaatctt tgcgggataa
    20881 cccggagatc gcacaggcgg ccagcaaccc catttcccgg ttctggcaga aacagcagat
    20941 caagcgccag tacgccaagg ccgcccggac agcgggccag accgcaggcg cggcggcaca
    21001 gggcgcggcc aagacagccg gggcctccac gaaagcggcc aaggccgcag ccaaagaaag
    21061 tgaacgggcg gcctcctttg tggcccgcca ctggaaaggg gcgctggccg tccttgtgtt
    21121 ggggcttttg atgctgctta tcatcggcgg cttacagtcc tgcaccgcca tgttcggcag
    21181 cgccggaagc ggcatcacgg cgtcctctta cttttccgag gatagcgata tgttggccgc
    21241 cgaggacgcc tacgcggagc tggaagccga gctgcaagac tatctggaca actacgaggc
    21301 cacccatgac tatgacgaat accattttga ccttgacgag atcagccatg acccctatgt
    21361 gctgatttcc attctgtcgg cgctccatga cgggatattt accatcgggg aggtacaggg
    21421 tgatttgtcc atgctctttg acaagcaata tatcctgaca gaaaacgtcg tggtagaaac
    21481 ccgttaccgc accgaaaccg atacatggac ggacgcggag ggcaacaccc atacagacac
    21541 ctaccaagtg ccgtatgact attacatctg ctacgtcacg ctggaaaact tcgacctgtc
    21601 ccatgtgcca gtctatatca tggacgagga aacgctaagt ttctattccc tgtatatgtc
    21661 cacgctagga aaccggcctg atctgttttc cggcagccag taccccaacg cctccaccct
    21721 gacgccgccg acctactacg acgtaccccc ggaggctttg gaggatgcca cctttgccgc
    21781 catgctcaaa gaggcggaaa aatatatcgg ttatccctat gtgtggggcg gcagctctcc
    21841 cagcaccagc tttgattgca gcggcttcat ttcgtgggta atcaatcata gtggatggaa
    21901 cgtgggacgg ctgggggcgc agggcctata taacatctgc acccctgttt ccagttcgca
    21961 ggccaagccc ggcgaccttg tatttttcaa gggaacctac gacacccccg gcgtgtccca
    22021 cgtcggcctg tatgtgggca acaatgtgat gctgcattgc gggaacccga tttcctacac
    22081 gaaccttact tcaaactact ggcaatccca tttttacagt tacgggcgtt taccttaacg
    22141 ccagaaagga gctttcaatt atggcaacca aacttgaccg catcgaaaag gacatccaga
    22201 aaaccaagtc taagatcgcg gagtttcaga aacagcttcg ggagctggaa acgcagaaaa
    22261 ccgaacagga gaatttgcag atcatccagc ttgtgcgcgg catgaacatg aagccggagg
    22321 aatttgccgc gttcttacgc agcggcgcaa tgcaggccgc ccctgccgca accccttacc
    22381 atgaacagga ggacaatgcc catgaagaat aagaccagac ggatttcccg tattctcccc
    22441 gcacttctgg ccgtgatgct ctgcgtcacg gcctttcccg ttaccgccct tgcaggcggc
    22501 aatgacccgg caccggcccc gctgccggag gctacaaccg aacccgctac gggcggtttg
    22561 gagcctgaaa cagacgaaac cggcaccgcc acggacggga cagaaaccga ggccgaaaaa
    22621 gataccggcc ctctgaccgg caaggacatc accgacctgt tttccgcgct gttcggttcc
    22681 aaggtgagca ttgccgccac ggacgacggc atccagatca ccaccggcac cgacaaaaaa
    22741 gaacctgaac agaccggcac cgtcaccacc aacggcggca ggctgaatgt ccgcaccggc
    22801 gcggggcttg acaagaccgc gttcacccag cttcccaatg ggacgacggt tgaggtagtc
    22861 ggcacagacg gcgactggat taaaattctc ttgccggagc gcatcggcta tgtccattcc
    22921 gactatatga ccgtcagcga aaaggaagta gcggctaccg gcgagggcgg tttttccctc
    22981 tccattgacc cggaggaaat tgcttctctg ctggaactgt tcaatggcgg cggggccagc
    23041 gccgccctgt ccccggacgg gaacctgtca ctgattgacg acatcggcag cgccgcgaaa
    23101 aatggcaagc agtttatcac cgtggaaacc aaaaacggca atgtgtttta tctgattatt
    23161 gaccgggacg acgagggaaa agaaactgtc catttcttaa atcaggtgga tgaagccgat
    23221 ctgctgacgc tgatggagga cggggaaacc gtcacccccg ctgctgtctg ctcctgtacc
    23281 acgaaatgca aggccggggc tgtgaacacg aattgcccgg tatgtaaaac caacctgacc
    23341 gagtgcagcg gcccggagcc gcaggaaccc cagccggagg aacccgaagc cccggaggaa
    23401 gaacccaagg gcggcgcggg cggcctgatc gtgttcctgc tggtggcgct ggcgggcggc
    23461 ggtgcggccc tttactattt caagttcaaa aagcccaagg ctgaaaccac cggcagcgac
    23521 gatttgggcg agtatgattt tggggaggac gaggatttgg aggacgagga acccgaaacc
    23581 gagtttgacc cggaagctga ttttgtgagt gaacaggagg acgaggaatg acatataaac
    23641 ttgtaatcgc ggaaaaaccc agcgtggccc gcagcattgc gggcgtgatc ggggccacgg
    23701 agaaacacga cggctatttg gaggggaacg gctatctggt gagctggtgc atcggacatc
    23761 tggtgtcctt tgccgacgcc ggacgctatg acgagcgttt caaaaaatgg cgctatgagg
    23821 atttgcccat tctcccggaa acatggcagt acatcgtccc cgacgacaag aaacagcagt
    23881 ttgacgttct ctgttcgctg atgcagcgcc ccgacgtgac cggccttgtg tgcgccaccg
    23941 acgccgggcg cgagggggaa ttgattttcc gtttcgtcta ccagatggcg ggatgccaaa
    24001 agccctttga gcgcctttgg atttcctcta tggaggacag tgctattaag gacggctttg
    24061 cccacctgaa accgggcggc gactatgatc cgctgtatca atcggccctg tgccgggcca
    24121 aggccgactg gctgatcggc attaacgcca cccggctttt ttccgtcctg taccacaaga
    24181 acctgactgt gggccgcgtc cagacgccga ccttaaaaat gctggtggac agggacgcca
    24241 agattaccga tttcaagaaa gagaaatatc acatcgtcca tatcacggcg ggcggcgcgg
    24301 acgcggtaag cagccgcttt tccgacgctg ccgaggcaaa caccgtcaag gcggcttgtg
    24361 caaaagcgca ggccgtttgc gtttccgtga cgcgggagaa aaagacggaa cagccgccca
    24421 agctctatga ccttaccacc ttgcagcggg aggctaaccg gcttttcggc tataccgcca
    24481 agcagaccct tgactatgcc caggcactgt atctaaagaa gctgctgacc tatccgagaa
    24541 cggatagtca atatcttacc gacgatatgc tgcccgccgt ggaaagcctt gtgtccggcc
    24601 tgtgggagct ggtgccgttt gccaagggcc tgaacctttc cccgcagttt gaccgcatcc
    24661 tgaacagcaa aaaggtgtcc gaccaccacg ccattatccc caccgctgaa tttgtgaagc
    24721 agggctttgg cactctggcc gagagtgaaa aaaagctgct gtccctgatc tgctgcaagc
    24781 tcttatgtgc cgtggccggg ccgcatatct atgaggccgt caccgccaca tttacctgtg
    24841 ccgggcagga gtttaccgcc aagggcaaga ccgtcctttc ccccggctgg aaagagattg
    24901 aacgccggtt ccgttcttcc ttaaagaccg acgccgacga ggacgccgag gcggtgcggg
    24961 agctgccgga gctttgcgag ggccagacct ttgcagacgt ggccgcctct gtcaccgagc
    25021 atttcaccac gccgcccaag ccctacaccg aagatacgct tttgtccgct atggaacggg
    25081 ccggggccga ggatatgccg gaggatgccg agcgcaaggg attaggcaca ccggccaccc
    25141 gcgccgccat tctggaaaag ctggtgcaga tgggctttgt ccagagaaaa ggcaagcagc
    25201 tcattcccac caaggacggc atcaatctgg ctgtggtgct gccggaggcg cttacttctc
    25261 cccagcttac tgccgaatgg gaaaaccggc tgaccgagat cgccaagggg caggccgatc
    25321 ctgacgaatt tatggacggc atcgagacgc aggcgcggga gctggtgcag acctattcct
    25381 gtatcagtga ggaaaagcag aaattgtttc aggccgagcg tgttcctatc gggacgtgtc
    25441 cccgctgtgg tgaggctgtc tatgagggca agaaaaacta ctactgcgga aaccgggcct
    25501 gccagttcgt catgtggaag aatgaccgat tttttgagga acgcaagaaa gcgttcaccc
    25561 cgaagatcgc cgctgcgctg ctcaaaaccg gcaaagtcaa ggtaaagggc ctctattccg
    25621 taaagaccgg caaaacctac gacgggacgg tgcttttggc tgataccggg ggcaagtacg
    25681 tcaactaccg cattgaacac aggagctaaa ggacagtaac acagcaagca tagggagtgt
    25741 ggctacactc ccggtaaaat cccccggccg cgtccctgcc gggccgggga tttttgcttg
    25801 ttggggaagt ccccaacccc ctattttttg aaacagaaca gagaaaggag tgaccgcgtg
    25861 aacgaagtat tttctatcca agtccataac cggcagtttt tggaacaggg caaacaaggc
    25921 gtctggctgg atttgcccac cacaaccgaa acgctgcaag ccgccctgcg ggatgttggc
    25981 attactgccg acaatccgca ggattttttt atcaacgggt attcctgccc ggaggacaga
    26041 caccttgcca ttccctatga catggtgctg gccgccgacg tggacgagct gaatttcctt
    26101 gccgcccggc tgggccagct tgacgccgcc gagatcgcag agctgaacgc cgccctgcaa
    26161 aatccccgtg gcggctttga gaatatcggc cagatcatcg actacaccga aaatgtggat
    26221 tactatgtgc atcttcccga cgttaggggg gatggacagt tgggcgacta ctacctgaac
    26281 cgttccggca tggtggatat gccggaggaa tggaaagccg ggattgatac ggcgcagttt
    26341 ggacgccaca ttgcccagca ggaacaaggc gtttttaccc agtacggcta tctggtgaga
    26401 agcggcgacg aatggcagcg cgtccatgag ggccagccgg tgccggagga ataccgggtg
    26461 atgcactacc cccagccgga agctgaccgg gaggaaccgc aggcccagca gccggaggca
    26521 tccgaaagcc ccgacaaagc gccgcccccg gttatcccga tcatgctgga cggcatgaac
    26581 agcaaagaac gcatgaaagt gattactgac cgtctggaaa ccggcgtaca ggagcttttt
    26641 gaaagtagcc gctatatggc ttacttatcc gctatgtcca agatgcacga ttacagtctg
    26701 aacaatacgc tgctgatcgc catgcagggc ggttcgattg tggcgggcta taacaggtgg
    26761 caggatgaat ttgaccgcca tgtgaagcgg ggcgagaaag gcattaagat actggccccg
    26821 gccccgttca aggttaagca gcagatggag aaaaccgacc cggccaccca gcagcccgtg
    26881 atcggcgcgg acggcaagcc cgtgaccgaa gaacaggaag tgacggttcc ggcctttaag
    26941 gtggtgacag tctttgacat cagccagacc gagggcaagg attttcccat gccctatatc
    27001 agtgaactta ccggcgacgt gcagcagtat caggatttct ttgccgcgct ggaacggaca
    27061 tcaccctatc ccataagcat tgagccgatt tcagacgggg ccaagggccg ctgcttctac
    27121 gcaaaacagc gcattgccat caacgagggc atgagcgaat tgcagaccct aaagaccgcc
    27181 atccatgaga ttgcccatgc caagctccac gccattgacc gggaggcccc cgccgaggaa
    27241 caggcggccc ggccagaccg cagcacccgc gaggtacagg ccgaaagcgt ggcctatacc
    27301 gtctgccagt attacgggct ggacacgtcg gactattctt ttggctatgt ggccgattgg
    27361 agcagcggca gggagttatc cgagctgaaa gcctcccttg aaaccatccg ggccacggcc
    27421 agcgaattga taaccgagat cgacggccat tttgcccagc ttcagcagga gcgcgaggcc
    27481 cggcaggaac aggaggccgt cacggttgac gttaccccgg aggcagcggc cccggcgcag
    27541 gccgaggaag aacaggcccc ggcccttgat ccggcagccg agccgcttgt gactgtgcta
    27601 tggagcgaaa gcccccagct aaaggacggc cagcaaatgc cgttgcatga ggccgacgcg
    27661 ctgtttgccc gtctggatgc agcatatccg gcagaggcag gctatgacaa aaccgcgttc
    27721 cgcattgact gtatctttca gggcgagccg gacagctacg aggggcggca ggattttgga
    27781 gatagggacg gttccctgat cgaacatatc cagagctacc accaatttta cgcgcaggac
    27841 gaaaactgga aaaagcatgt aatcgctaca accggcatag agggctggga gcaggacaag
    27901 gcccatcggg atatgctgtt aggcgagttt gtcccctata tgaagctgca ttgcagcctt
    27961 gcccaaatgg aacagacggc gcagggccgc ttacagtccg gggaaaccct gacgccggag
    28021 gaaacggcct atttgggggc gcttctctct tatgtgcagg agtgccgccc catgctcaat
    28081 cagggccagt atcagttgcc ggagccgccg aaactggctg acttcgacca gagcttgcag
    28141 gactacaaag cacaggtaca ggccgagatc gcgcaggagg ccgccgcagc cggtatgacc
    28201 gtggaggaat acgcggcggc tggctatgaa gcaccccaac aggacacctt ttccatctac
    28261 cagcttcgag gcggggagga aacccgcgac tatcggtttg agccatacga gcgtttacag
    28321 gccgcagggc tggccgtgga cagtgccaac tatgaccttg tttatacggc accgctggat
    28381 aaaagcacgt ctttggagga tatttaccgc acattcaaca tcgaccaccc ggcagatttt
    28441 aggggacaca gcctttccgt ttccgacgtg gtggtgctgc accagaatgg acaggacacc
    28501 gcccactatg tagacagctt cggctatatg gaagtgccgg agtttttgcg ggaaaatccc
    28561 ctgcgtaccg ccgaactgtc tacggagcag aacgaaaaca tgattgacgg cattatcaac
    28621 aatacgccgc ccgaaccgca gccggaggaa cccgaacagc tatcttttga ggatgtggca
    28681 gttgcttccg gccagacaca ggaggaaccc ccggaggctg cgcccccgca aacggctgtc
    28741 cgctattatc ccatcaatga gggagccgcc cgccgcgcca aggaagccat gagcttttct
    28801 gactaccggc ccggcagcgc cacggcggaa taccggcact atgtcgatca ggccgtggaa
    28861 attgcggagc gccagaaaaa gcgtgtggag ccagagtatc acgaaaagat agacagcctc
    28921 cttgacacct acgcccgcaa gctggccgag aacatgaata agggctatga gattaccgcc
    28981 cgcgtcccct ctgtcctgat tgccgggccg tccaatttcc cggtacgggc gaaagaaaag
    29041 cagaacgccg ccagtgaccg caacatggag gaatttcagt acattcaggg cttgcttgac
    29101 aaaatccgca gcaccggcat gggtggtatc agcgccgacg atccgcaggc cgtttccaag
    29161 ctggaaaaga aactggaaaa gctggaagcg tcgcaggagt tgatgaaggc cgtcaatgcc
    29221 tactaccgca agcatgggac gctggacgga tgcccccatc tgatcgaaag aggcattgaa
    29281 aacctgaaag cggatatggc gtcgggctgg cactatgaga aaaaaccgtt ccagtcctgg
    29341 cagctctcca acaataacgc cgagatacgc cggttaaagg gccgcattga ggaattgacc
    29401 cgccaaaagg aggcggccta tgtgggatgg gagtttgacg gcggcactgt ggagatcaac
    29461 cgggtggcca accgcctgca aatcttcttt gaggggaagc cggatgctgc tgtacgcgac
    29521 gagctgaaaa gcaacggttt ccgctggtcg cccaaggccg gggcatggca gcggcagtta
    29581 aacgacacca caatccgcgt cgctgaccgt atcaagtgca tccagcccct ttccggcgaa
    29641 aagcccagcg ccttacagct tgcggcccgc agggagaaag aaaagccctc tatccgggcg
    29701 cagctcaacg cggccaagac cgaacaggcc aagcagccac cggcgcggga aaaatcaaag
    29761 ggattggagg tagagtaaat gcagaagttt gaaaatgtgg acgttctggc cgcgctggaa
    29821 cagatcatgc ggcagaacac cgcgttttat caaagtgact ttggcattga caaagacatt
    29881 atcaggcggg atgccgccag cgatcaggcc gcagacaaga ccctgctctg gatgtcccgg
    29941 ccctccggga cgtactgttt ccgggaacgt gatgttttcc tgaaagacac ccgacagtac
    30001 aacacatgga aattttacgg ggagcagacc cgtgacaaga tactggccta cgcggtggag
    30061 ctgaccggca cacagggcgg cactatccgg ggcaatctct atgagctgga ctatccgcag
    30121 catttccggc acgtcattga aaccgcccag ccggtgagtg tgaaccggct cttttatgag
    30181 catggcaccc gtgacatccc ggagagccag cgttttgacg gaagccctga ccgggtattg
    30241 ggaaactttt tgtactatga ggcccagccc catgacccgg ctgtgctgca ggaggcgcta
    30301 cggacggagc agcacagccg ggggcgggcc gtccccggcg atttcaaagt ccacgtcacc
    30361 gctttgcatg acagccggat tgaaaccgag gcccggcgta ttgtggacag cctgaaagat
    30421 ctgtccgcgc ctaacagccc caataaaacg catttcatgg tggagatctc cccgcacttt
    30481 gcggcgattg cttccaccaa ggataatgac cggctctttg ccatgctgcc ctataaatcc
    30541 ctgtgtttta ccgggatgaa aggcaggcat ggcgtgtatg ccgtgattaa ccgggacgag
    30601 cgccgggatg tgagtattcg caggccccgg ccctctatcc gcaagcagct atccgacagc
    30661 aaacaggccg ccagcccaaa aaaggcggcg gccagaacca aaaagaatga attggaggta
    30721 taaggaatga tgcactttac cgtggaggaa gaaaacctga tctgtatgta ccacaatgca
    30781 gaccggcgca gaacgataaa caggctcacc gccgtcatgc cggttatgga tggggatatg
    30841 cgggcgcagg cccagcagac cctttccaag ctggaacgca tgacggatgc cgactatgac
    30901 ggccagaagt tccacttcac agacgaataa cgaacagcag acgccgggcg cggcggccat
    30961 gtggtcgctt gcgtccggcg tcttttcttt ttgcctattc ctacgcattt agaacccggt
    31021 attgtcgggg ataggatgaa gtattcgctt gcccctgcaa acatgcggga gaagccttgc
    31081 agcgggcggt tttcaatccc ttaaatgcgt aggttgcagc tataattaga cccctgaaac
    31141 agatatagcc gcgcagcggg tgtatctgtt tcaggggtgt gcaggtgata gccgcaaagc
    31201 ggcgtaagag ggtgcagccc tcttgccgtc tatctctgtt ccagcgggaa gctcggcaat
    31261 gcttccagca gtttcaggga aatgcgctgc cgtatatctt cgtcaatgac tttcttcttt
    31321 ttgccgtttg cctgtctgat ctccaccgtg gaaagctcgt tgatgtagtc agcataatgg
    31381 gccaacactt tttccgtggc ccacctctca ccggcaacgg cggctttgat cgtttcatag
    31441 tccagcagct tttcttgtcc gtccatcctg atacccccgt cagactgatt ttttctatga
    31501 taccatattc ggaagcatgg aaccagagaa aacggcgctt ttctgctggt aaattctacg
    31561 catttagaac agcacttcgg cggggatagg ataaaacacc cacatacccc gctgaccatg
    31621 ccggaaaagc cttgaaatat aagggctttt acagctctaa gtgcgtaggt ttccagtatc
    31681 ttttccgctg gcgctcggcc tctttgcggc ggcgcatccg tttggagcag gccgcgcagt
    31741 atttggcccg gttagacttc ggcgtgaacg tggccccgca ctcacagcag cgtttcactt
    31801 cgtcccggtc tttggtgatc tcggcataca gggccgcatc cagcgggagg acagcggcct
    31861 taaaccagcg gcacagaagc gaataggaaa tgctctgtac gcaaatacat tcttcgccgt
    31921 cgtccagcaa caggcagttg ccgtcacaat agttgcagca ctcatgcgtc agcttccggg
    31981 ccttgcgata ttgagggtaa ttcattcgtg gaatactcat agctcttgcg tccattcctt
    32041 tcccggcgtc atacgcaaaa tgccgtccac attctgcttg atgatgccgt attcctgcat
    32101 ctgctttttc gcttcgccgt acttctcata cagccgttcc ttttcctcgg ccaatcgctt
    32161 gtactcggct ttcagggcgt acagatcggg gagctttttc acaccctgtc cctttagggc
    32221 ctttgccgca gcttcataca aaatcaacgt gctttcatgc tcacgccgga attttgcctt
    32281 atccgctgca ttgcggtatt ccatagccac gggccagagc tgcttgtagg tagaaatatt
    32341 ctttatcagc accgccatat ccgcaagccg gtgttccata gctttgaggg tagcggcggc
    32401 ctcgtcgctg gcggcggtga tctcggccac tttgctttcc aaatccgggt aggtgtctat
    32461 cccatgttca gtcaggaaat tcaaagtctt tgcggcctgc ttcaaattgt ggagcttcgc
    32521 ccacctctca tagcctgccg actgctgggc cttaatgttg ttttccagat caatccgcaa
    32581 agaaatcccc ttgcgctctt tgggcgctct ggtgataacg cggcctttga tacgctcttt
    32641 gatggcttcc tcggtgtagg cttcccccaa tgtcttgcag cgggtaaagc gttcctgtcc
    32701 gggagcgcgg aaagaaataa actttcccgg cttgatctca tagccctgcg cctgcatgag
    32761 ccgcaggaaa tcatcaaaat cttttgcctg cgggatagcg gcgtcaatgg ctgctttgag
    32821 cttcgctttc cagctcgtcc ctttccgctg ggcgtcccac tcggcatagc tcttgccctt
    32881 actctggccg ggcttcacca cggacaatcc gttttccttg cacagcctgt cgctggtgcg
    32941 ccggatatag gcatagctct gtttgttgga aatgtacttg cgctgattta ccatatccac
    33001 ggcacagaaa ataatgtgat tgtggacgtg gcccttatca atatgggtag tcagcacata
    33061 gggatatttc ccttgcagca cttcctcggc aagctgcttc ccgatctcat gggcctgttc
    33121 cggcgtggct tcgccggggg caaaggattg tatcaggtgg tggcccagat tattgccctt
    33181 ttggtatgcc tgcgccagca gcatttcaaa ttcaatgtcc gctgtttcat aagagcaggc
    33241 aaaggaggcc accagcagct tgccgtcagt tttgtccggg ttctcgatgt agtcaagggc
    33301 ttttttcagc gttgacttga taggatgtat ctttgtaact gccatatctg cgccagcgcc
    33361 ccctttatat cctcgatgtc ctgtgcgtac accggcccca taccgttcag cctctttgca
    33421 atctgattga cgttgacgcc gatcttctgt atctcggcgg tctgcgcccg gatgtcgctg
    33481 gtgtccatgt tgacgatata gccgtcaatg agcatcttcc gggcgtaggc tgaaaagttc
    33541 ttcgtatgca gcagcgccat tttctgttca atcatagccc gttcctccgg cgtcacaggg
    33601 acgcgcagca cgatttttcg ctttctgttt gccatgcttc accgtccttt ccattcaggg
    33661 gtttggggat ttccccaaca agcaaaacgg acgcggcccg gcagggacgg ggcaggccgt
    33721 ttttccggga gtggctacac tccctatgct tgctacgtta ctgtttctcc actaacaaga
    33781 cgtttccaaa gccccaaact acccgcaaaa tagccctctg gaaagaaaaa agtgcaaaaa
    33841 aatagaagct acgctgtgca gctcccgcta aaagtaaaac agaggatgcc agttacacat
    33901 cctccgtttc attcttcttc ggcttttcaa ttagtatggc gctgtcaatc gcgccctcga
    33961 tgatcggcag gtattcttcg gggcagagtt tcagcttgtg gctgaccctt tgccgcagtt
    34021 cgctttcctc ccgcatgatc tccgggttaa agtagcgttc cacaggaagc ccgcaggctt
    34081 taataagctg tatgacaacc ggcagactgg gaatggcccg tcgttttcga tgttggcaag
    34141 atagcgccag tcaatattta ttttctctgc cattgctttg cgcgaaacgc gctttgcttg
    34201 ccgggccgct ttcacatccg cgccgaaagt ttcaaagccg ggacaatctt caatattcgc
    34261 catatcgcac ctcccactta cattgtatat ttcatactct gcccgtggaa tgttggtata
    34321 tgcacctttc ttaaagttta tatttcacat tttgtttctt ttattcttcg agcaaaagaa
    34381 ttataatgta ccctgtggag gtgtactatg gactacatga cgttgaaaga ggcaggcgag
    34441 aaatggggtg tgcccccacg atggataaac tactattgtg ctgcgggacg catccccggc
    34501 gctgtaaaga tggcgacgat ctggctcatt cccaaaactg cggaaaagcc gattgacagg
    34561 cgtacaaaga aaggaaaggc ggttactgaa tagtataatg aaaccggcgc attttggata
    34621 tggttttgaa gagagagaaa gcatggtatt ttgtcacgga aaaactataa gatgatagat
    34681 ggcaggctgc tccagaccga taaaaagtat tctcatctga aacagaaaga aaagatttac
    34741 acatggatgt atgaagaagc gaaactttat catgacagaa atggaaaatg cccgaaacaa
    34801 agacgaggaa gctgctgctg tatcagccgt atatggtaga attgaaaagg ccggcatctg
    34861 gattctttat ggtgaagtct ccagacattg gataactgct ggtctaatgc gcctttgagt
    34921 atggggtgat tgattttaat accggggagg tacggctttt tgaggaaaat attctgggat
    34981 ttacatttgg cgattattac atttcctgta actgcaagga cacggatgat gaagatatga
    35041 ggaatataga cttgctgatt ttctactgtc ttgaacggta ttaggactga atctgctgcg
    35101 cggagtgcgg caagagcgac cggagggagt acacacaggc cctgcctgtg tgaaaagcca
    35161 taccgcaagg tgcattcgca aaaaagaggc cgcgcatttt gctgaggctt ggggtgtccc
    35221 caacaagcaa aacgagaacg ccgcaggcgg gcaagtggtg gatcagaata tccgtaaagg
    35281 atattctgat ccattgcttg ccagtattat cgggatgttt tgacaaccgc tgtaatcgaa
    35341 acatcccaaa cattaagaag gtgttaatta ttattatctt gatttaattc gtttaaacca
    35401 ataatataga tacatacacc atgaaaagaa gcgagtatcc caatgacgga tgattaaaat
    35461 ccgaaaagaa atcgctttga aactacaggg aaactacaga ctgttatgtt atcttcttaa
    35521 aatggaggga tttttatgtc gatacgaatt ctacttgtcg aggatgatga tcatatctgt
    35581 aatacagtaa gggcgtttct ggctgaggca ggatatcagg tggatgcctg cacagatgga
    35641 aatgaggcat acaccaagtt ttacgaaaac acttatcaac tggttattct tgatattatg
    35701 ctgcccggta tgaacgggca tgaacttttg cgtgaatttc gtgcgaaaaa tgatactccc
    35761 attctgatga tgacagccct gtcggatgac gaaaaccaaa tccgggcgtt tgatgcagag
    35821 gcagacgact atgtaacaaa gccattcaag atgcagattt tactaaagcg ggtggaagcc
    35881 ctgctgcggc gcagcggtgc gctggcaaag gaaatccgtg tcggcaggct gacacttctg
    35941 ccggaggatt tcacggtact ttgtgacggt acagagctgc ccctgacacg aaaagaattt
    36001 gaaatccttt tgctgctggt gcagaacaaa ggcagaacct taacgcatga aatcattttg
    36061 tcacgtatat ggggatatga ctttgagggt gatggcagca cagtccacac tcatatcaaa
    36121 aatttgcggg ccaagctgcc ggaaaatatc atcaaaacca ttcgcggtgt aggataccga
    36181 ttggaggaat cataataatg gaaagaaaag ggattttcat taaggttttt tcctatacga
    36241 tcattgtcct gctactgctt gtcggtgtaa cagcaacact gtttgcacag caatttgtgt
    36301 cttatttcag agtgatggaa ttacagcaaa cagtaaaatc ctatcagcca ttggtggaac
    36361 tgattcagaa tagcgatagg cttgatattc aagaggtggc agggctgttt cactacaata
    36421 accaatcctt tgagttttat attgaagata aagagggaag cgtactctat gccacaccaa
    36481 atgccaatac atcaaatagt tttagaccca actttcttta tgtggtacat agagatgata
    36541 atatttcgat tgttgctcaa agcaaggcag gtgtgggatt gctttatcaa gggctgacaa
    36601 ttcggggaat tgttatgatt gcgataatgg ttgtattcag ccttttatgc gcgtatatct
    36661 ttgcgcggca aatgacaacg ccgatcaaag ccttagcgga cagtgcgaat aaaatggcaa
    36721 acctgaaaga tgtaccgccg ccgctggagc gaaaggatga gcttggcgca ctggctcatg
    36781 atatgcattc catgtatgtc aggctgaaag aaaccatcgc aaggctggag gatgaaatcg
    36841 caagggaaca tgagttggag gaaacacagc gatatttctt tgcggcagct tctcatgagc
    36901 taaaaacgcc catcgcggct acaagcgttc tgttggaggg aatgcttgaa aatatcggtg
    36961 actacaaaga tcattctaag tatctgcgcg aatgcatcaa aatgatggat aggcagggca
    37021 aaatcatttc cgaaatactg gagcttgtca gcctgaatga tgggagaatc gtacccatag
    37081 ctgaaccgtt ggacataggg cgcacggttg ccgagttgct gcccgatttt caaaccttgg
    37141 cagaggcaaa caaccagcgg ttcgtcacag atattccagc cgggcaaatt gtcctgtccg
    37201 atccgaggct gctccaaaag gcactatcca atgtcatatt gaatgcagtt cagaacacgc
    37261 cgcagggagg cgaggtacgg atatggagtg agcctggtgc tgaaaaatgc cgcctttttg
    37321 ttttgaacat gggcgttcac attgatgata ctgcgcttcc aaggctgttc accccattct
    37381 atcgcattga tcaggcgcga agcagaaaaa gtgggcgaag cggtttagga cttgccatcg
    37441 tacaaaaaac gctggatgcc atgagcctcc agtatgcgct ggaaaacacc tcggatggcg
    37501 ttttgttctg gctggattta ccgctcacat caacattgta aatatttaaa acttaaatga
    37561 tttt
//
LOCUS       DBBGSZ010000024        36400 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.024, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000024 DBBGSZ010000000
VERSION     DBBGSZ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 36400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.024"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..781)
                     /locus_tag="ACIZE5_001684"
     CDS             complement(<1..781)
                     /locus_tag="ACIZE5_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGC6108812.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEID"
     gene            929..1261
                     /locus_tag="ACIZE5_001685"
     CDS             929..1261
                     /locus_tag="ACIZE5_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HGC6108813.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            1373..2581
                     /locus_tag="ACIZE5_001686"
     CDS             1373..2581
                     /locus_tag="ACIZE5_001686"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HGC6108814.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            2735..3190
                     /locus_tag="ACIZE5_001687"
     CDS             2735..3190
                     /locus_tag="ACIZE5_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108815.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            3552..3827
                     /locus_tag="ACIZE5_001688"
     CDS             3552..3827
                     /locus_tag="ACIZE5_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108816.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            3840..5918
                     /locus_tag="ACIZE5_001689"
     CDS             3840..5918
                     /locus_tag="ACIZE5_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGC6108817.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            6081..7964
                     /locus_tag="ACIZE5_001690"
     CDS             6081..7964
                     /locus_tag="ACIZE5_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGC6108818.1"
                     /translation="MKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKTS
                     LLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVRA
                     YEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIST
                     LSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDRY
                     FLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMRA
                     GVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRINDQ
                     TLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQE
                     NEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEKR
                     RLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVAD
                     KLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEW
                     ETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEW
                     VED"
     gene            7976..8923
                     /locus_tag="ACIZE5_001691"
     CDS             7976..8923
                     /locus_tag="ACIZE5_001691"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HGC6108819.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            8943..9470
                     /locus_tag="ACIZE5_001692"
     CDS             8943..9470
                     /locus_tag="ACIZE5_001692"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HGC6108820.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(9533..10186)
                     /locus_tag="ACIZE5_001693"
     CDS             complement(9533..10186)
                     /locus_tag="ACIZE5_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HGC6108821.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            10318..11160
                     /locus_tag="ACIZE5_001694"
     CDS             10318..11160
                     /locus_tag="ACIZE5_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGC6108822.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            11318..12214
                     /locus_tag="ACIZE5_001695"
     CDS             11318..12214
                     /locus_tag="ACIZE5_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGC6108823.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            12217..12930
                     /locus_tag="ACIZE5_001696"
     CDS             12217..12930
                     /locus_tag="ACIZE5_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HGC6108824.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            12950..13468
                     /gene="msrA"
                     /locus_tag="ACIZE5_001697"
     CDS             12950..13468
                     /gene="msrA"
                     /locus_tag="ACIZE5_001697"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HGC6108825.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            13465..13692
                     /locus_tag="ACIZE5_001698"
     CDS             13465..13692
                     /locus_tag="ACIZE5_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HGC6108826.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            13844..14395
                     /gene="lepB"
                     /locus_tag="ACIZE5_001699"
     CDS             13844..14395
                     /gene="lepB"
                     /locus_tag="ACIZE5_001699"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGC6108827.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(14478..15020)
                     /locus_tag="ACIZE5_001700"
     CDS             complement(14478..15020)
                     /locus_tag="ACIZE5_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HGC6108828.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(15257..15655)
                     /locus_tag="ACIZE5_001701"
     CDS             complement(15257..15655)
                     /locus_tag="ACIZE5_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC6108829.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            15915..16775
                     /gene="ylqF"
                     /locus_tag="ACIZE5_001702"
     CDS             15915..16775
                     /gene="ylqF"
                     /locus_tag="ACIZE5_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HGC6108830.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            16768..17535
                     /locus_tag="ACIZE5_001703"
     CDS             16768..17535
                     /locus_tag="ACIZE5_001703"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HGC6108831.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            17591..18448
                     /gene="dprA"
                     /locus_tag="ACIZE5_001704"
     CDS             17591..18448
                     /gene="dprA"
                     /locus_tag="ACIZE5_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HGC6108832.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            18570..20648
                     /gene="topA"
                     /locus_tag="ACIZE5_001705"
     CDS             18570..20648
                     /gene="topA"
                     /locus_tag="ACIZE5_001705"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HGC6108833.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            20617..21993
                     /gene="trmFO"
                     /locus_tag="ACIZE5_001706"
     CDS             20617..21993
                     /gene="trmFO"
                     /locus_tag="ACIZE5_001706"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047151 - tRNA
                     (uracil(54)-C5)-methyltransferase activity,
                     5,10-methylenetetrahydrofolate-dependent [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HGC6108834.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            22191..23096
                     /gene="xerC"
                     /locus_tag="ACIZE5_001707"
     CDS             22191..23096
                     /gene="xerC"
                     /locus_tag="ACIZE5_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HGC6108835.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            23133..23681
                     /gene="hslV"
                     /locus_tag="ACIZE5_001708"
     CDS             23133..23681
                     /gene="hslV"
                     /locus_tag="ACIZE5_001708"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HslVU peptidase proteolytic subunit"
                     /protein_id="HGC6108836.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            23695..25095
                     /gene="hslU"
                     /locus_tag="ACIZE5_001709"
     CDS             23695..25095
                     /gene="hslU"
                     /locus_tag="ACIZE5_001709"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HGC6108837.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            25113..25904
                     /gene="codY"
                     /locus_tag="ACIZE5_001710"
     CDS             25113..25904
                     /gene="codY"
                     /locus_tag="ACIZE5_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HGC6108838.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            25986..26861
                     /locus_tag="ACIZE5_001711"
     CDS             25986..26861
                     /locus_tag="ACIZE5_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HGC6108839.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(26993..27631)
                     /gene="plsY"
                     /locus_tag="ACIZE5_001712"
     CDS             complement(26993..27631)
                     /gene="plsY"
                     /locus_tag="ACIZE5_001712"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HGC6108840.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            27758..28192
                     /locus_tag="ACIZE5_001713"
     CDS             27758..28192
                     /locus_tag="ACIZE5_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HGC6108841.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            28358..30403
                     /gene="parE"
                     /locus_tag="ACIZE5_001714"
     CDS             28358..30403
                     /gene="parE"
                     /locus_tag="ACIZE5_001714"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HGC6108842.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            30415..32865
                     /gene="parC"
                     /locus_tag="ACIZE5_001715"
     CDS             30415..32865
                     /gene="parC"
                     /locus_tag="ACIZE5_001715"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HGC6108843.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            33142..35373
                     /gene="pflB"
                     /locus_tag="ACIZE5_001716"
     CDS             33142..35373
                     /gene="pflB"
                     /locus_tag="ACIZE5_001716"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HGC6108844.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            35617..36378
                     /gene="pflA"
                     /locus_tag="ACIZE5_001717"
     CDS             35617..36378
                     /gene="pflA"
                     /locus_tag="ACIZE5_001717"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HGC6108845.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
BASE COUNT        12662 a         6296 c         7719 g         9723 t
ORIGIN      
        1 cgtcaatctc gtggacgatc ctcttagctt cagttaattc actagagcta acgaccatat
       61 agatgatttt ttttgaatta ccagagaatg cgccttctcc agaaaggaaa gtcacacctc
      121 tttgcagacc ggtcatcagt agtggtgcaa tctcttcgct tttgttggag acgacaagta
      181 gaccttttgc agaatatccg ccatctaaga tcgaatcaat cacacgactg aaaacatacg
      241 aaacaatcaa cgtatacatc atacgtttca agtcgatata ggttaatgaa gcaagtaaga
      301 cgatgatatc aaatgccaat agggaacgcc ccatagtgat gccgtaattt tgttctaaaa
      361 tccgagcgat aatatcactg ccgcctgttg ttccacccat gcggtagacg atcccgcttc
      421 ctacacctgc aactaaaccc gcaagtagag aaacgatcag tagatcatgc tgtaaattga
      481 tttctagtgg aaccctttgc cagatccata aaaagaatga caaagaaagt gtacctagaa
      541 cagtataggc caaggaacgt ttaccgagga tctttcctcc tagtaaaatc aatgggatgt
      601 tgattaataa agtcgtataa gctggatcaa taccaaataa agctcttaag atcaaggtga
      661 tccctgagac tcccccttct gctaaatgat tagcgatgtt caagtaaaca agaccaaatg
      721 cataaatact tgttcctata atgataaaaa gaacttcttt tactgttttt cgtttgacca
      781 tatgaattcc agctttcaat tatgtatttt cacagaattt ccatttagaa attccttcct
      841 aaatgtagca tggaaattcg attttctcaa ttgctcttat ctaggatttg cgttaaagtt
      901 ttggtaagat agttttggag ggaaaaagat ggataaaaag cgttctttat acagtatgca
      961 gcaggaagtg gatgaatata tccagcaatt caaggtgggg tatttctctc cattagctca
     1021 gatggctcga ttaactgaag aagtaggtga attggcaaga gaagtcaacc acacttatgg
     1081 agaaaaaagc aaaaaggctt ctgaaccagt taactcggta gcagaagaac ttggtgatgt
     1141 tttattcgtt acgatgatca tggctaattc attgaatatc gacttaactg aagtttttga
     1201 aaaaaacatg gaaaaattca atcaaagaga ccataatcgc tttgagcgta aggacgagta
     1261 aacaagatga agtggtcctg gccttgaaga ctctgaaacg gacttgtcaa acagtcacca
     1321 tgcaactgag tctttatctc aggacaagaa acacgcagga aaggttggaa aaatgaaatt
     1381 aaaacaatta cctctggaat accaaaaggc aattccagtt ctgaaaaaat tagagaatgc
     1441 aggatatgaa gcttattttg taggtggaag tgttcgtgat atcttgctga accagccaat
     1501 ccatgatgtg gatatcgcaa caagcgcatt tccagaagaa atcaaacagc tttttccaaa
     1561 aacgatagat attgggatcg aacatggaac tgtgttggta ttagaaaatg atgaacaata
     1621 tgagatcacc acatttcgga cggaatcaac ttatcaggac taccgtagac cagatcatgt
     1681 cgaattcgtt cgttcgttgg cagaagattt gaaaagaaga gattttacga tcaatgcgtt
     1741 tgctttgaaa gaagatggag aaatcatcga tttgttcgat ggtctgcaag atctagaaga
     1801 acagatcttg cgagctgtag gcaatcctca tgagcggttc catgaagatg ccttacgaat
     1861 gatgcgcggg ttgcgttttg tcagtcaact agggttcaaa ttagaggaag aaaccttcta
     1921 cgccatcaaa gaaaaccacg agctattagg taaaatatct gtagaacgta taaatgtgga
     1981 attcatcaag atgctcttgg gaaatgaacg ggccgcggga atccatgcat ttattgaaac
     2041 agagtgctac atttgctgtc ccggtttgaa agaagaaggc gaagcacttt tacgttttgc
     2101 tgaattacca tccgtcccat tgaaagaaga gagccaagca tgggcattat tgatcagcca
     2161 actggatcta aaagaaaatg agattcgttc ctttttgaaa tcgtggaagt gttctaacca
     2221 aatgattaaa gacgttcaag cacttgtcca aggactacga caacgagaaa ctggagcttt
     2281 ggaaccattc gaattgtact tcttaggcaa aaaacatgca ctgcaagtag aagaattgat
     2341 gatctatttt gacgaaacac ctcagatgga tgccgtagga gaatcctatg atcgtttacc
     2401 tatcaagtca ttaagcgaat tagcagtaga tggtaaaatc ttgctagaag aaactggaaa
     2461 aaaacctggt aagtgggtta gtgaagcttt gcaattagct gaaaaagccg tcgtagaaca
     2521 aagaataaaa aatgataaaa aacaggtttt ggatttttta tcgaaagaaa aattgattta
     2581 aaaaacacta gactgtatct gctcagcttt gttggctact taaagtgggc agatacgtca
     2641 ttagaagaaa aaacataaga tgtgaccact tacataaatt tgtgctaaac tgaggtagta
     2701 caagaataaa ttacatcata aaggagtctt tttaatgagt aaagaaatga cagcgctaaa
     2761 attttatttt agaaatggag aaacctggac gatcaaccgc cgtcatatcg gcgatctttg
     2821 gatcaaacaa atcacaacaa gttttggacg aatcaatggc agtgaatttg ttgaaatcca
     2881 tccgtgtgct ggatttaaaa tcgaaatctt ccatgaaggg gacgcagttg cgacacatga
     2941 tatcaaccta ggcggactgg aaatgggcat gtttaatcgc gcattgaaat acgaagatat
     3001 cgagcgaatg gaaatccttt accgaaatgg cacacctgat cttgtgtact tcccatatct
     3061 agataaagga acagaaggat tagacaatca atatcaatca acaaaaatca gcgaaaaaac
     3121 aggtaacttg tatatcgtga tcaatccaga tcaacgtgta gaagatgtat acggggaatt
     3181 tttcgaataa atcgattttt acgcaaaaat gaggctgtga aagagatgtg tcttattact
     3241 actgataggc tgtctcttcc acaccgttta ttcagaataa gggactgtga caagattttt
     3301 gtcgcagccc catttttttg ttgtgataaa agaacaagaa aggcaggaat gggaaagtaa
     3361 acatcctttt gtcagaaact tttatctttc ttaagtttta cttgatatct gatactattt
     3421 ggaatagaat gaggcgttga aaaatttatg gaaatttcta actagcaata aacgatgaaa
     3481 caatgaaata tttttcatcc aaaaagaact ttgctataat gatggaagtt tgtgtatagg
     3541 agatctggaa aatgagagag agttttgaac aacaaaaaaa actgttgcat gatcgctatg
     3601 gcgccctttc gatggatgac cgccgtcaaa tactttgtaa gttgcgtaaa agaaatatat
     3661 tgatgtatcg tcagttggaa cgtctgaaac atgatctgct tcgtttggag tcaaaacgtg
     3721 tacagtgtga attagagggg aaccaaacac aggttgaagt agtcgaaacc aaaattttaa
     3781 agaaaaaaga acaattttta aaaatgctta cacaaaataa aaaataaagg ggatggacga
     3841 tggaatttgc tgagttagtt attgtatttg cagtaacgat caccttatcg aacatagcta
     3901 gccgcatttt gccaatgatt ccagctccac tgatccaaat tttccttgga gtggtattag
     3961 gtctgacaga gtggggacaa tcaatcgatt ttgaacctga attgttctta gttatgatta
     4021 ttgcaccatt gttatttaga gaaggagaaa aagcagatat ttcttcgatt ctcaaaaatt
     4081 tcgggacaat tttgttcttg gcatttggag gagtcatttt gacccttgtc ggggtaggtg
     4141 cgacgttatc attcctgttg ccaagtgtcc cacttgctgc ctgctttgct tttggagcag
     4201 cgttaggtcc gacagatgcg gtagcagtca gttctctttc tggacgagtg aatatcccta
     4261 aaaaggcgat gcatattttg gaaggagaag gtcttttgaa tgatgcatct ggtgttactg
     4321 ccttccagtt tgctcttggt gcgctgatca ccggatcttt ttcagcagta aacgcgggga
     4381 tgagtctagt agtttctagt attgggggag ctttgatcgg ctttttgctt gtctggttca
     4441 aacaaaaaat aattcatttg atcgaaaaag catcagcaca agatgtcaca gggtatctgc
     4501 tgatcgaact tttgcttcct tttctagcct atgtattggc agaggcattt gatgtatctg
     4561 gaatcattgc tgcagtggca gcaggtattc tccaagcttc tggttttagg aaaatctctg
     4621 tgtttgatgc agaattgtcg agcttgtccc acagtacatg gacaactatt gcttttacac
     4681 tgaatgcatt agtatttata tttttaggaa tcgaattgac gcaagtgttc tcgccagtat
     4741 ggggagacgg tttatatcca aacggtcttt tattagcgat tatcgtatta atctctgtca
     4801 tgctttttgt gatcagattc atttctatca gtctttttta tgtattcaaa gatggcagta
     4861 aaaagttcaa aaaacagttg aacgagatct tgatcttaac atttggcggt gtaaagggaa
     4921 cagtcagttt ggctacgatt tttattttgc cattttcaat caataatatg atgttttacc
     4981 agcggtcttt gcttttgttt ctgacggcgg gtgtcatctt agtgactttg gtcataggga
     5041 tcattgtctt gcctatgctg acggaaacag aggaagcgaa aagcacggat ttgaatgctt
     5101 tgatgatttt agaagaggtc gttgaagttt tgcgaaaaga aataaaggaa attgatcgta
     5161 atacaaaaga atttttagcc actgaagcag tgatagaaaa ttatcaagaa cggatacgtg
     5221 atctgtactt ggaagattta accgatgatg aaaagcaaga agtacaagaa atacaagcac
     5281 tgattttgtc gatcgaacgg gatggattgg atgaaagtta tcgttcgggc aagctttctt
     5341 ctaatggtta tcgtttttac tcccgttttc tttctcgatt cgaacattct atcacaagcc
     5401 agattttgtc ttttatcggc ttttggttca ttgttgtccg taggttaatg cgaatcgttc
     5461 tccatccgaa aatgttttgg caaagaagat atgctgatcg tcagacattt attagtgatg
     5521 aagatatcca agaaatcaga gagacatatc aaaaaaatac tcagttgatt attgaaagtt
     5581 tagataactt gactgatatt tatgatgaaa cgatggttca attttttatc cagcaacgca
     5641 aacttgaagg aataaaaatg aactcgggga atttgatttc ttcgtggatg atccagcaag
     5701 atagtctgtt tacgaaaaaa atgctaagag gttattatct tgaaagaaaa atcattgatg
     5761 aatacgaagt tgctgaaaaa atcacgacgt tttctgcgaa cagctatcgc aggaatatca
     5821 atttgttaga atcttatacg atgaacaaac catctgataa cttttctttc cgatttgcgt
     5881 ttcgagcaaa gtcaaaaaaa acgagtccaa taaaataaaa aggtaaaaat tttcaagttt
     5941 tataaaaaac aaaacatatc agaacaggat cgaatcggtc ctgttctttt tttgagaaca
     6001 caaaaagaac aaataccaaa aaaattttcc tgaagttcac tatttttatg atacaatatc
     6061 caagataagg agggaacatg ttgaaagaat taaaagtaac tgacctcaaa aaaacttatg
     6121 gtgaaaaaga tttgtttgac cagatttctt ttttggtcca cgaaaaagac cgtatcgggt
     6181 tgattgggac gaacgggacg ggtaaaacaa gtctcttaaa tattattgcc ggtatcgata
     6241 gcagcgacgg tgatcggcaa acagtgtttt atccaactga ttaccgtatt ggttatcttt
     6301 ctcaagcagc tgaattttcc gatgaattaa ctgttctcca agcagtcttt caaggaaaca
     6361 gccccttgat ccaaactgtt cgagcatatg aggaagcatt gatcgaacta ggggaaaacg
     6421 gagaagaccc tgatgtgcaa aaacgttatg ctaaagcaga agaacaaatg aataaagaag
     6481 atgcttggac tacagatacc aacgcaaaga ttattttgca aaaattagga atcagtgaat
     6541 tagataaaaa aatcagtact ttatcaggtg gtcagaaaaa acgagttagt ctggcgcaag
     6601 tgttgattga tgaacccgat ttactattac tagacgaacc aacaaaccat ttagattatg
     6661 aagcgatcga gtggttggaa aactatttga aacaataccg tggcgcacta ttgatggtta
     6721 cccacgatcg ttattttcta gatagagtag caaaccgaat cttcgaactt tcatttggaa
     6781 aattatacga gtataaagga aattatgaag cttacgtctt agaaaaagca gaacgtgatc
     6841 gtgtagaagt agaacaagaa gaaaagcgca agcggcttta taaacaggaa ttagcttgga
     6901 tgagggctgg cgtacaggca cgtggcacca agcagcaagc acggatcaac cgtttcgaag
     6961 atctaaagga gaacttgtac caagtaaacc aagaagatga tttagagctg aacctagcga
     7021 cacaacgttt agggaaaaaa gtactggaaa tcaaagatgg cagttaccgt ataaatgacc
     7081 aaacactgct agaacattta gatttattga ttcaatctcg ggaaagacta ggtattactg
     7141 gtaaaaatgg tgcgggaaaa tcgacattgc ttaatattct agctggcaga attcccctgg
     7201 atagcggtac aatgtctatc ggtgaaacgg ttcatcttgc gtattataca caagaaaatg
     7261 aagaaatggc accagataaa cggatgattg cttacttaca agaagctgct gaagaagcaa
     7321 aaacagcaga tggcagtcaa atcggagtag cagaattact tgaacgattt ttatttccaa
     7381 gatttatgca tgggacactg ataggcaaac tttcaggcgg agaaaaacgc cggttatttt
     7441 tgttgaaact gctgattcag caacctaatg ttttattatt ggatgaaccg accaatgatt
     7501 tggacatagc aacattgacg attttggaag attattttag aagttttcca ggtgctgtga
     7561 tcactgtttc ccatgaccgt tatttcttgg acaaggtagc agataagtta ttagtattcc
     7621 aaggaaacgg aaaacaagaa ctttattacg gaaacatgtc cagttattta ctgaagcaaa
     7681 aagagaccca gcagcctgct gaaaaagcga aaccaaaaat acagagcaag gaacctgctg
     7741 aaaagaagaa attatcttac atggaacaaa aagaatggga aacgattgaa gatgagattg
     7801 cagaacttga agaaaaaatc tcattgctcc aagaagagat gaatcatcaa ggagataatt
     7861 tcactcgatt acaagaattg caaaacgacg tatctgaaac agaagcacaa cttgaagaaa
     7921 aaatggcacg gtgggaatac ttgagtgaat gggtagaaga ttaggaggaa aaaggatgga
     7981 acaagcgtat cttgacttag gaagaaaatt gttggaagaa gggcatcgta aagaagacag
     8041 aacaggcaca ggcacattaa gcttattcgg ataccaaatg cggtttgatc tgcaaaaagg
     8101 gtttcctttg ttaacaacga aacgagtacc ttttggattg atcaaaagcg aattgctttg
     8161 gtttttaaaa ggagatacga atatccgcta tctattacaa aataaaaacc atatttggga
     8221 tgaatgggca tttgaacgct acatcaaaag tccagactat aatggaccag atatgactga
     8281 ttttggccat agatgtttga cagatcctga attcaatgaa gaatataaaa agcagagcaa
     8341 gcttttttgc gagaagatcc taaccgatga ttcctttgct gaaacatacg gcgatcttgg
     8401 acacatctac ggctatcaat ggcgtcactg ggaaacaaaa gacggtggct ttatcgatca
     8461 aatcaaacaa gtgatcgaag caatcaaaaa gactcctgat tctagaagat tgatcgtttc
     8521 tgcatggaat ccggaagatg ttcctagcat ggctttgcct ccttgtcata cgatgtttca
     8581 attttatgtt caagagggac ggctaagctg ccaattgtat caacgcagtg gggatgtgtt
     8641 tctaggcgtt ccgttcaaca ttgcaagtta tgcgttgctg actcacctaa ttgcacatga
     8701 aacaggttta gcggttggcg aatttgttca cacattagga gatgctcatc tttatatcaa
     8761 tcatatcgaa caaatgaaag aacaattgag ccgagaaata cgcgcatttc cgactttagt
     8821 tttgaatcag gaaaagcagt cagtatttga ttttgagatg gaagatatcc aattagaagg
     8881 atatgaccca catccggcga tcaaagctcc tatcgctgtt tagaatcaga aaggatgaga
     8941 aaatgttagc tgcaatttgg gcacaggatg aaaacggatt gattggaaaa gaagaccgtc
     9001 ttccttggcg tttgccaaat gatctgaaat tcttcaaaca aatgacagaa gcaaatacac
     9061 tagtgatggg acgaaaaaca ttcgaaggga tgggtagccg tccgttgccg aatcgtcaga
     9121 cgattgtttt gacgagagat tcttcctata aagcagaagg cgtgcatgtc atgcatagtg
     9181 tggaagacgt gcttgctctg gaaaaagaaa cagacggtat ctttttcatc gctggagggt
     9241 cagctgttta tcaagaattt ctgccatttt gtacgatatt ataccgtaca gtcatccatc
     9301 atgtattcga tggagatgct tattttccac ctgttgactg gtctgattgg tcactgatca
     9361 atactagtca aggagaaatg gatgaaaaaa atcgttatcc gcatcaattt gaaacgtatc
     9421 agcgtaatga gaatcctgta aaaagcggga caggcgaatt gacgatataa aaaagctatg
     9481 gatagactag ctgttattta gagctgtccc atccatagct ttattttttt tattaagtaa
     9541 agaataaaac agagaagtac ataaaacctg cacctaacat aacaaacaaa tgccaaacaa
     9601 catgcatata gcggatagaa ttcaagctat aaaagaatgc gcctatcgtg taagaaagcc
     9661 cgcctgctac catcaaaata acaccagtca ttccaagaga gtgataaaga ggaacagcag
     9721 ccacgacaca gagccacccc ataaaaatat agatgatcgt agatactttt gatactctct
     9781 cccgtttatg caacgtcaac gctttatata taatgccaag aatcgcaaac aaccagatta
     9841 atacaaataa agtccaacct agccatcctc ggatactcag caaacaaaaa ggagtataac
     9901 ttcctgcaat caaaagaaaa atcgaactat gatcgaatac ttggaacacc ttttttgctt
     9961 ttgtaaaaat caatgaatga aacaaagtag acgttaaaaa taaaagaatc atcatcgatc
    10021 catagatagc ataagagaca atatggaggg aggaatgcaa gtgggcacct tttactaaaa
    10081 gaaccactag tcccgcgata ctcaatccag tcccaattcc atgggtgact gcattaaaca
    10141 cttcatttaa tatttcatac gttcgattaa atttcgtttt ttccatgaaa acggctcctt
    10201 tactaggtgt aattaatgaa aaatcattat ttgtctgtta tactaaaaat agaaattgtc
    10261 ttacatgtag tttaacatga ataaggcatc ttgttaaaga aagagagaga gaaaataatg
    10321 acaaatgtaa aaatcgtaac agattcttca tgtacgatgg aaaaaaatgt acgcgatgct
    10381 ttaggcattc gtgtcatgcc gctatccatc atgatcgacg gaacagtata tcccgatgat
    10441 gaccaactag acggcgaaag atttatggaa atgatggcga aagcaaaaaa tctgcccaaa
    10501 acaagccaac caccaattgg agaattcatc tcgatgtatg atgagctagg agaagacggc
    10561 agtgaagtga tttcgatcca tatgacaaaa ggcttgagtg gaacagtaga agcagcaaga
    10621 caagccagta atctaacaaa aacgaaagta acggttatcg acagtgatac cactgaccaa
    10681 ggattatctt ttcaggtaat tcgagcagct gaattagcaa aagaaggtaa aacagtagag
    10741 aaaatccttg aagaagtcaa aaaagtacaa gacaatacaa aattatacat cggaatatcc
    10801 acactagata acttggtaaa aggtggaaga atcagccgaa caactggttt gctgtctagt
    10861 gttttgaaca tacgcgtggt gatgaatttc gcccattctg aattaatccc tgtaactaag
    10921 gggcgaggaa agaaaacgtt cgataaatgg tttaataatt tgaaaaatga actgaaagaa
    10981 ttgccaaatg tgcgacaaat cggtatttca catgcggatg caaaagaatt ggcgcaagaa
    11041 ttcaaagagg gtttgcaaga attattcccg gacatgcata tccctgtact gcatacgaat
    11101 ccggttatcg ctacgcatac tggtaaagac gcgtttgcaa tcatgtatta tgtagattag
    11161 tcgaaaagag gataagccct cagcctgaaa ggcttgcagc ttattctctt tttctttata
    11221 aaattaggaa aataattgtt ttcttttttc ataaagacta cctttttgat aaaatttttg
    11281 ataacattag aaccaatcga atacaagagg tgaaaaaatg aaattaacga aacgacattt
    11341 gatcctcgtt ttgttcccat tattaattgc gatcatcatc tatgcaggtt tagctgcttc
    11401 tataccgaaa gctggcccac taatgaaacc agtaactact gtgagagaag atccaaataa
    11461 aaaagaaaaa cttcactaca tagctatcgg agattcgctg actgaaggag taggagatca
    11521 aaccaagcaa ggaggattcg ttccccttgt cgcaaatgat ctaaaagacc gttataattt
    11581 gaccgcggtt gaaacagaaa actatggtgt aaatggtgaa cgaagtgacc agatcttaaa
    11641 gcgagtaaaa acaaaagaag aaattcgaaa caatatcaaa acagctgatt ttatcacact
    11701 gactgttggc ggtaatgatt tgatgaaagt tatccaaaat aatttattcg ggttaacggt
    11761 caattccttt aaaaagccac tgaaaaacta tcaggaaaat gtcacagaac tattggaaga
    11821 atttcgatcc ctcaataaaa ccgcacctat ttacatttta ggcatctaca atccatttta
    11881 tttgaacttt cctgagatca ctgacatgca gacaattgtt aacaattgga acaaaggaac
    11941 agaaacggtg acaaaaaaaa tgccgaactg ctactttatc ccaatcaatg atttgcttta
    12001 tcaaggattg aatcaggaag taggtgtcac agaagaagga acagatcaaa caactagcac
    12061 gacagaaaat ctaaatggca tcaaaaataa tgtgctctat gaagaagatc atttccatcc
    12121 aaataattta ggttatcaat tgatggcaaa tgcagtgaga gatcagctga tcgagacaca
    12181 aaaccaatgg ttagagaagg aggatgatca ataaacatga aaacaagatc tgacgtatct
    12241 tcaaacaaaa caaagaaaac aaattactgg aaattcgcct tccttatcct tcttggggta
    12301 gtacttggtt cgaccgtatt tttaggcagc cgtatttttg ctaatcggga accagaactc
    12361 ccagaaatac cagctcttac ggaaagacaa ggagatcctg tcttaacgat caattcaaat
    12421 aaagaaaaag tcaatcaaat catcagcttt ttccttagtg agtatcaaaa agatagtgat
    12481 attgaatata aattttattt ggaaaatgaa gcactactca atggtacttt cgaagtacta
    12541 ggttttccta tcgatttcta tttatatttt gatccgtatg tgatggaaaa cggaaatgtc
    12601 caactaaaag ctagaagtct ttctatcgga acattgagtt tgccaatcaa agatgtgatg
    12661 aatatgatca agagaaacta taaattacca gattggatcg aagtcaatac agatgatctg
    12721 actatcatgc ttaggttgga tcaattccga atgcaaaacg ggatgtatat taaagcagat
    12781 aaaatcgact tagtaaatga tgacattcgg tttagtctat atttgccaaa agatacctct
    12841 gatgcttcaa acaactcaaa taccaacaaa actagcacca gcagtactga aagcaagaca
    12901 aaagaaaata aaaaatcatc ggatgagtag tattagaggg ggaatcataa tggaacgagc
    12961 aatatttgca ggaggctgct tctggtgtat gatccagcct ttcgacacgc ttcctggtat
    13021 ccatacagtg atgtcaggat atactggagg gcatgtacca gatccgactt atgaacaagt
    13081 aaaaagccaa acgactggac atacagaagc agtggagatt atctatgatc caacattgat
    13141 ttcatatgaa caattagtag aactttactg gcagcaaact gatccaactg acgctttcgg
    13201 acaattcgag gatcgcggtg acaattatcg cccggtgatc ttttatttga cagaagaaca
    13261 gcggatcatt gctgaaaaaa gtaagaaaca gttagctgaa agtggacgtt tcgaacagcc
    13321 aatcgttaca aaaatcgaac cagcccaacc attttatcta gcagaagaag accatcaaga
    13381 gtattataaa aagcatcctg aaaattttaa aagaaaccat gcacgccggg ctgcctttat
    13441 cgaagaaaat tggaggaacg aagggtgaat cgaagctttt ttcattattt aatgacactg
    13501 cgaggcggtg gcacacatga tgctttatct gttttcgcta cagaagccgg taaagacatc
    13561 caatttccta agcacagctc tagctacgaa gaaatttcta attatctgga actgaatgtc
    13621 gactatttgc cgtccatgga tatctttgac gaagcatggg aaaaatattt agaaaataat
    13681 catgacatat aagagatagt tttgtacttt atgatcaaaa aagttttttg tccaatagcc
    13741 taattgaaag aattattttt atttcagcta tctagtcgca tttttttgat atttttctta
    13801 taataaagaa agaatgaaaa aaagagggat ggattgatag agattgacaa aaaaacaacg
    13861 ctatattaat cgcttctggc ttgtattcaa atacttactt gtttctgtat tccttgcgtt
    13921 catgttgcgg ggatttttat tcatcccggt accagtggaa ggcaattcaa tggaaaacgt
    13981 gttgaagcaa ggtgatatgg ttgtgatgga aaaattttcg gagatcagac gatttgatat
    14041 tgttgttttt caattagcag atggcacgat ttatatcaaa cgagtaatcg gtcttccagg
    14101 agaaaatgtc agctaccaaa atgatcaatt gaagatcaat gggaaagtag ttaaggaacc
    14161 ttatctaact aaaaacctga aatcagatca tgcaaatgca tcctatacga cggactttac
    14221 actacaagag ctaacgggac aatccaagct tccggaagat aattattttg tacttggaga
    14281 taatcgaaga gtttcaaaag atagtcgttc gtttggcacg atcaataaaa ctgatattct
    14341 aggtaaagca agatttgtct attatccact tgatgaaata aaatggatcc agtgagaaac
    14401 aataaagcgt gcagtctgtt gagactgcac gctttattgt ttaatccaaa atcagtttac
    14461 taccttagta cgtaaaatca aacagctcgt ttaaacactt ttctagcctc taaagttttg
    14521 ataaatgaat aaacaaccat tatttgaata gggatttgga tcatattcct gatgaatcta
    14581 cctagaaaaa ttactttgaa atctgcacca aacaaaacag acatcagcca agaattgata
    14641 aaaaggctga ctgggatcat aatcaataat tgggcagcga tgacggaagg caggtttatc
    14701 tttttatgat ataaaaataa gccattaata aatccaccaa ggaaagccgt gataagaaaa
    14761 gcagcttgaa acgttcctga accaaatatc gtgaaattta aagtgttcga caacatttca
    14821 agcaaaccag cccagatcgg tccatataga taacccataa gcgccatact taaaaatccg
    14881 aatgtgattt gaaaataagc aggaccaatc gctatcttgt ataagatgac atcaagggct
    14941 aataaaagag cagaggtcga caacaatctt gcattcattt cgggcaatct aaaaacgtct
    15001 tttgcaatca aagtgttcaa aatattctct cctttgtcag ttaataataa aaggatacca
    15061 taaaatcacc aatgtgtcat gacacattgg tgatttacat acactggcat ctaacaatta
    15121 aaaaaagggt gagaagactg cttttataaa ctgtaaaaaa gagattgtac gaataaaaaa
    15181 aatagaggcg gagaatactt atcgtatcat ccgcctttgt ttttttgtta taaaaaacgt
    15241 cagattagtt atctgcttac atcttcatcc atacgggttc taatgtattt ccgtctagat
    15301 cttggacttc taatgaaaac atttcttctt caggcattcc catatctact tcgtggaaag
    15361 taccaccatt ttcttttgca atttgagcaa atttttttac ttcatccgca ttttcaacac
    15421 taaacgaaat caaagcacca cttgtttttt tattatcagc tatttcttta tcttttataa
    15481 attttttata aaaatcatga gagagaagca ttatccaaaa agtgtcatcc cataccattg
    15541 aaccagcttc ttcagtagaa aattcttcat tttttttaaa acccagcttt tcataaaaag
    15601 caacggaacg attgacatca gcaacaggaa aattaacaaa aaccatacta ttcatttgtt
    15661 tcgtctcctt tctgttttgt tcgtctatca tctcttattt aggaaacgct gtcaaaaatt
    15721 tagattcata tatagaaacc aaaataaaaa tttgcatcat caaaaaagtg aagatgtgat
    15781 agaatgagga ctggttcact ttcacttaac taatagatgg aatttcttta taataaaaaa
    15841 gtgaatttat attgaaaaag aaaaaaacaa gtaaagccgg ggaatattcc ggtatgaaag
    15901 gaatggagag aacaatgacc atccaatggt ttccgggaca tatggcaaaa gcccgacgag
    15961 aagtttctga aaaaatgaaa tatgtggaca tcgtatttga attggtagac gcacgattac
    16021 ctttatcttc tcgtaatcca atgctagatc agatcattca gcaaaaacct cgccttgttt
    16081 tattgaataa agcggatctg gcagatccac aacagacaaa gctgtggcaa gaatattttc
    16141 gtaaacaagg ccatcttgca ttagctatca cggcacaaga aagtaaagga attaaaggtc
    16201 tagtacctgc ggctaaagaa gcattgaaag aaaaacgggc aagagatgct gctcggggga
    16261 tcaagcctcg cgctattcgg gcaatggtct taggtattcc aaatgttggg aaatctacgt
    16321 tgatgaatcg actagtaggc aagaaaattg cacagacagg aaataagcct ggcgtaacaa
    16381 aaggtcagca gtggcttcgt ttaggtaatg agttggaatt gttagacaca ccagggattt
    16441 tatggcccaa atttgaagat gaagaaatcg gcaaaaaact agcgctgaca ggcgcgatca
    16501 aagaccagct tgtccattta gatgatttag cgatttacgg attagacttt tttgcccgat
    16561 attattcagg aagaatcagc gatcgttatg gtttatcaat cgagcaagaa gaaaaattgg
    16621 caccggaatt actgatggat attacagcaa aacgtgggta taaagaagac tatgatcgtg
    16681 gcagcgaatt agtcgtgcat gatattcgtc aaggaaaact tggacgatac acactggatc
    16741 gttgcgaaga aatggagcaa aaaagtgatg actgaatcca tccaaagtat caaagaacga
    16801 ttgaaaagca tacagagaat agatgatcct acactagaat cattaagaaa tgatccacgc
    16861 aaaggcgtgc agcaagcact ggcttctttt gaacgacgat tgaaaaagga agcattaatt
    16921 aaggaaaaat atgaagaaat gttttgcttt gaaaagcaag ggtacgcaca aggtcaccaa
    16981 tggattgccg gcattgatga agtaggaaga ggaccattag ctggacctgt cgtggcagct
    17041 gcagttatct tgccgaaaaa tgagatcata ttagggctga atgactccaa acaattatca
    17101 gagaaaaagc gagaacttct ttatcaacaa gttcaagaaa aagccctggc aatcgggatc
    17161 gggatcgttg atcagcagac aatcgatgat gtgaatattt atgaagcaag taaattagcg
    17221 atgatccaag cagtagaaaa attgtccatt gtaccaagct atttgttgat cgatgcgatg
    17281 accttggatt tgcctattca gcaggaaaaa ataatcaaag gggatgcacg atctgtgtcg
    17341 attgctgctg caagtatcat tgctaaagta tatcgagacc aattgatgaa agaatatgac
    17401 gtgctttatc ctggatatgg tttctcgcat aatgcaggtt atggaacaaa ggaacactta
    17461 gaaggacttg aacgacaagg aattacgcca atccatcgta aaagttttgc acctgtaaaa
    17521 aaatatttac aataaaaaac agccgctttt acgtatctta ttagaaagag agacgaaagg
    17581 cggttttatg atgtatcaaa tagaagaaaa tttattgaaa cttgcttata caaaaggaat
    17641 cagtagtcaa ggaaaatggg cacttgctaa ctggatgatg cagtatcctt ataaagaaat
    17701 cggatttgaa gacatcatta agataggtaa aataaccaaa caccgggagc tgtttcgcaa
    17761 aagttggcag gaaattcacg ctaactgggg caaaatccaa tcgaaacagt cgtttatcac
    17821 ttgctttgat cccaaatatc cccctcagct gcttcacttg acctatccgc caattgtact
    17881 gttttataat ggtgatctat ctttactttc ttgtaacatg ttaagcgttg ttggtggaag
    17941 acacacttct gctttagcca aaaaaacagt ttattattta ctaaaaccag tgatagaagc
    18001 tggatatgtg atcgtcagtg gctgcgcgaa agggatagat acatacggtc accaagcagc
    18061 aatctctcat ggtggacgga caatcgcagt cattggaaca gggatagagc aagtctatcc
    18121 tgctgaaaat cgtgacttgc aagaggtgat tgcaaatgat catcttcttt tgagtgaata
    18181 tcctcctcaa tccggcccga aaaagcattg ttttccaatg agaaatcgga ttatcgcagc
    18241 tttgtctaaa ggaacatgtg tctttgaagc caagaaaaaa agcggctctc tgataacagc
    18301 acagcaagca ttggatcttg gaagaacagt tttttctgtt ccaggaaata ttttaacaga
    18361 acattctacc ggatgtcatc atttgatcca agacggtgca gtttgcacgg tttcgggtga
    18421 agatatcttg gcagaattta aagaataaca ccatactttt catttgcttt tcttgacaaa
    18481 cgttttctga atggatatga ttagctacga tttgtatgaa tcctctttta atagtaggaa
    18541 cacgacaatg gaaaggagtc cattcagtaa tggcgtataa atatttagtg attgtagaat
    18601 cacctgcaaa agccaagaca attgagaaat atcttggacg aaactataaa gtaatggcca
    18661 gtgttggcca tataagagat ttaccgaaaa gtaaaatggg tatcgatttt gaaaacaatt
    18721 atgaacccca ttatatttct atacgcggaa aaggcgatgt catcaaaagc ctgaaagccg
    18781 cagcaaaaaa agctcaaaaa gtttacttgg caagtgaccc ggatagagaa ggagaagcga
    18841 ttgcttggca tttagcgtac ctacttgggt tggatctgaa agaaaaaaat cgggtggtct
    18901 tcaatgaaat cacaaaagac gcagtcaaag cagcttttaa ggaaccaaga acgatcgatg
    18961 tagatttagt agatgcacag caagctcgtc gtaccttaga cagaatcgtt ggttattcga
    19021 tcagtcctat tctctggcgt aaggtcaaga aagggttaag tgcaggacgt gtccaatctg
    19081 tcgctttaaa aattattatt gaccgtgaaa aagagatccg agaatttgtt ccagaagaat
    19141 attggagcat cgacggtaat tttaaaaaag ctcgcaagaa attcaaagca aatttctggg
    19201 gaatcgacgg taagaaaaag aaattaccag atgcacaaag tgtaaaagaa gtcactgcta
    19261 gaattgatgg aacagacttc gaagttaaaa aagtagaaaa gaaagagcgc aaaagaaacc
    19321 ctgcgaatcc tttcactaca agtagcctgc aacaagaagc tgcccgtaag ttaaactttc
    19381 gaacaagaaa aaccatgatg gtagcacagc aattatatga aggaatcact ttgggtaaac
    19441 aaggaacagt cggcttgatt acatacatgc gtactgattc tacccggatt gccgatacag
    19501 caaaagcaga ggccgcagca tttattgaag atacgtatgg aaaagaattt tctagacatg
    19561 atcaccgaaa gatcaaaaat gctcaaggcg cacaagatgc ccatgaagct gtgcgtccaa
    19621 cgagtgtgct tcgtacacca gatgaactca aacaatattt agataaagat caattgaaac
    19681 tttatacatt gatctggtca cgttttgtgg ctagtcagat gacaccagct attttagata
    19741 caatgaaagt gacattagaa caaaatggtg tcatcttcat tgcgaacggt tcaaaaatca
    19801 aattcaaagg attcatgcaa gtgtatgtgg aaggtagaga tgacggcaaa gaagagaaag
    19861 aaaatattct tccagaactt gaagaaggcg atgtagtcca atctgttgat attgaaccaa
    19921 aacaacattt tactcaacca ccagcacgtt ttagtgaggc tacgttgatt cgtgcactag
    19981 aagaaaacgg ggtagggcga ccttccactt atgcaccaac acttgatacg atccaaagac
    20041 gctactatgt aaaattgaca caaaaaagat ttgagccgac tgaactagga gaaattgtca
    20101 attcattaat ctgtgaattc ttccctcaaa tcgtcgatat ccatttcaca gcagaaatgg
    20161 aaggagattt ggataaaatt gaagaaggca cggaagcgtg ggtcaaagtg gttgatcgtt
    20221 tctataaacc gtttgaaaaa gaactgacga atgcggaaga aaaaatcgaa aaaattcaaa
    20281 tcaaagatga accagcagga ttcgattgtg atgtctgtgg acatccgatg gtgataaaat
    20341 tagggaaata tgggaagttt tatgcttgca gtaattttcc tgattgtcgg aatacgaaac
    20401 caatcgtaaa agaaatcggt gtgacttgcc cagtatgtca tgaaggacaa gtcattgaac
    20461 gaaaatctaa gaaaaacaga ctattctatg gttgttcccg tttcccagaa tgtgaattca
    20521 cttcttggga taaaccagtg ggcagaaatt gtccaaaatg tgacggatat ctggtcgaga
    20581 agaaagtcaa aggcggtaaa caagtagtct gtgtaaatgg agattacgaa gaagacatcc
    20641 aaaaataata gaaaagaggt tctttcattg aaaatggtaa atgttgttgg agcagggctt
    20701 gccggaagtg aagctgcttg gcagatcgca caagcaggag tccctgtccg tttatatgaa
    20761 atgcgtccag tcaaatcgac tgaggcgcat cacacaagta attttgctga actagtatgt
    20821 tccaattcat taagaggaaa cagtttggct aatgcagtag ggttattgaa agaagaaatg
    20881 cgccgattga attcggtagt aatcacttcg gcagatgaaa cagcagtgcc agctggtggt
    20941 gccttagctg ttgaccgcga ttctttttct gaaacaatta cccgaaaagt caaagagcat
    21001 ccattagtaa cagtgataaa cgaagaaatt actgaaatac cggaaggaat caccgtagta
    21061 gcaacaggac ctttgacttc tcatccatta gcagaaagca tcaaagcatt caatggttca
    21121 gatggttttt atttctatga tgcagctgca ccaatcgtag acaaagctac gatcgatatg
    21181 gataaagtat atttgaagtc ccgctatgac aaaggagaag cagcttactt gaactgtccg
    21241 atgacagaag aggaattcaa agctttccat gaggcactaa tcaatgccga agtggcagaa
    21301 cttaaatctt ttgagaaaga aaaatatttt gaaggatgta tgccaattga agtaatggca
    21361 cagcgaggat tcaaaacgat gcttttcgga cctatgaaac cagttggatt ggaagatcct
    21421 aaaactggca aacgtcctta tgctgttatc cagctgcgtc aagacaatgc tgcagcttct
    21481 ttatacaaca tcgtgggctt tcagactcac ttgaaatggg gcgagcaaaa acgtgttttc
    21541 cggatgattc ctgggttaga aaatgctgaa ttcgttcgct atggtgtgat gcaccgaaac
    21601 agctttatga attcgccaga attgctgaaa ccgacttacc aatcaacgaa acgcgaagat
    21661 ctgttctttg caggtcagat gactggtgta gaaggctatg ttgaaagtgc agcgagcgga
    21721 ctacttgctg gaatcaacgc cgcacgctta gcaaaagaaa tggaaccagt cgagtttcca
    21781 caagaaacag ctattggaag tatggcttac tacattactc atgcggaagg aaaacatttc
    21841 caaccgatga atgccaacta tggtctgttt cctgaactgc cagagcgcat tcgagacaaa
    21901 aaagcaagat atgaagcaat tgcacaacga gctttaaaag ctaatgaggc aataaaaaca
    21961 gaattagaaa aaactgcaat cccaaatgag taaggaaact ccatgaagag ggtgagacgg
    22021 atagtctcgc tctttttctt gcgtttttct taagaatttc tcaaacaaaa tgtgaggaat
    22081 tgcgccaatt gtgaacaaac ttagaaatat tggttaaatt ctgacaattt atttgtcttt
    22141 ttataaacgc tgtgctaaat tattctctgg gacaaaagga aggtgagaaa atgacagaag
    22201 ccacgtggga acaaaaattt ttgcgttatt tgattgtcga aagaggatat tcagaaaaaa
    22261 cgaaagaagc atatgaagaa gacattctcc atttcaaaca ttttttggag gaatctggag
    22321 acgctgatct gctgaaggcg gaatatttta cggttcgtgt ctatttgagt gcattagctg
    22381 atcatcgtcc tagctatagc agaaattcta tcagtcgcaa gatagccagc ctacgttcgt
    22441 tttatcagta tcttctcaaa gaagaagtga taaaagaaaa tccattttct tacgttcatc
    22501 tcaaaaagaa aaatttgaga ctgccacgtt ttttttatga aaatgaaatg caagcacttt
    22561 ttgacagcgt agcaggagat agtcctttgg atttgaggaa ccgcgcttta ctggaagtcc
    22621 tttacgggtc aggcatccgt ttaagtgagt gtagcagttt gtcggtatca gacattgatt
    22681 ttgattcaga ggtcatgttg atccatggta aagggaacaa agagagatat gctcctctag
    22741 gttcttttgc tcaagatgct ctgcaagaat atttcaggga aggccgccag gtattgatga
    22801 caaaatatca cgaagagcat gatatcgttt ttgtgaatca tcatggaaaa ccaatcacgc
    22861 ctactggaat tgaatatgtc ttgaatcaaa tgatcaaaaa aagcagtttg gatagtgata
    22921 tccatcctca catgctgcgc catacatttg ctactcattt attaaataat ggggcagatt
    22981 tgcggacagt ccaagaattg ctaggacatg ccaatttatc gactacccag atctatgccc
    23041 atgtaacaaa agaaagttta caaaaaaact atcgttcttt ccatccaaga gcgtaaaaat
    23101 aaggaaaaga acaaatttag gaggaaacaa acatggtcga atcaccattt cattcaacca
    23161 ctatctgtgc cgtcgaaaaa gacgggaaat ttgctatggc tggagatggc caagtaacaa
    23221 tgggtgaatc tgttgtcatg aaaggcactg caaagaaagt acgacgtatc tacaatggag
    23281 aagttgttgt aggtttcgcc ggaagtgttg cagatgcgtt tactttagaa gaaaaatttg
    23341 aaggcaaact aaacgaatat aacgggaatc tacaacgcgc agctgtcgaa ttagctcaag
    23401 aatggcggac acagcaatct atgcaaaaac ttgaagcgat gctgatcgta atgaatgata
    23461 aagaaatgct tcttgtttca ggtacaggag aagttatcac accagatgat ggtatcttag
    23521 ctatcggatc aggagggaat tttgcgttgg ctgcagcccg agcaatgaaa aactatgctc
    23581 aaaacgacat gagtgcgaaa gaaattgcag aaaatgcgtt aaatattgcc gcagatatct
    23641 gtatctttac taatcataat attatcgtag aagaactgta agaggtgagt agatatgtat
    23701 gaattaaaac aaacaccaag acaaatcgta agtgaattag atgaatatat cgtaggacag
    23761 cacgcagcaa aaaaatctgt tgccgttgct ttgcgtaacc gctatcgccg tttgcagtta
    23821 gatgaaaaaa tgcaacaaga tattacacca aaaaatatgc tgatgatcgg acctacaggg
    23881 gtcggtaaaa cagaaatcgc acgacgtttg gcaaaaatcg tcaatgcacc atttgtcaaa
    23941 gtcgaagcaa caaaatttac tgaagtcggt tatgtcggaa gagatgtaga atcaatggtt
    24001 cgggatttag tagaaaatgc gatccaaatc gtagaaaaag agcagtacag ccgtgtatac
    24061 acaagtgcta aaaaaaatgc agaaaaacgt ttggtaaaaa tcttggtacc tggtatcaaa
    24121 aaagaacaga aacaatccac taatcaattt gaacaaatga tgaatctttt taatgctagt
    24181 cagcaaaata ccgctgaacc gcaagaagaa gtgacagaag atattcgaat caatcgccgt
    24241 acagtcttgg aacaactaca aaagggttta ctggatagtc gtgaagtaac cattgaagtt
    24301 gaagaccaaa agaaacctgc accaatgatg aacaatggat tggagcaaat ggggatcgac
    24361 ctaaatgaaa ctctaggtgc tttgacaccg aagaaaaaag tggaacggac ggtaacagtc
    24421 aaagaagctt tagagttatt gatcaaggaa gaatcagcaa aattagtcaa ggatgctgat
    24481 atccatagtg aggcaatcaa attagcggaa gaaagtggaa ttatttttat cgatgaaatc
    24541 gataagatca cttctaaatc acagcaatct ggagaagtat ccagagaagg cgtccaaaga
    24601 gacatattgc caattgtcga aggttcacaa gtaaacacaa aatacgggat catccaaaca
    24661 gatcacgtcc tattcattgc ttcaggagct ttccatttgt ctaaaccaag tgatctaatt
    24721 ccagaacttc aaggacgctt cccgatacgg gtagaattag atgatttgac agctgaagat
    24781 tttgtgaaga ttctgaccga accaaataat gctttagtaa aacaatacgt cgcgttgatc
    24841 ggtacagaaa atgtgtcagt tacgtttaca aaagaagcaa ttgaacggat cgctcaaatc
    24901 gctttcgatg tcaaccgtga cacagataat atcggcgcac gcagactgca taccattttg
    24961 gaaaaactac tagaagatct attatttgaa gcaccagata tgcaaatggg agaaataacg
    25021 atcacagaag catatgtgga tgacaaactt ggctcaattg cggcaaatga agatttaagt
    25081 cgctatattt tataaaaaat cggaggacga caatgacaga cttgctaacg aaaacccgca
    25141 agataaacac acttttgcag caaaagaata cttttgacat gcaagcagat ttgccttacg
    25201 ataaaatggc tgtcacacta ggtggtattc ttgacagcaa cacctatatc ataggaagtg
    25261 acggagtatt actaggttat aatgaacgtc acgatgtgaa caatgaacga atcaaaacaa
    25321 tgtttgttga gaaacaattt cctgaatctt atactgatac agtggcacag ttgatgaaaa
    25381 ctgaagctaa tatcccaatt actagtgata ttactgcatt tccggtagag tcaagagaga
    25441 aatatccatt tggtctgacg actgtcgttc cgatctttgg agctggcgaa cgtttgggta
    25501 cgattatctt atctcgtatg gaacaatcgt ttgcagatga cgatctagtc ttagcagaat
    25561 atggagctac ggttgtcggt atgcagatcc tttatcagaa gtctcgaagc atcgaagcag
    25621 atgtacggag tgcaacggct gtccaaatgg caatcaacac attatcttat agcgaattga
    25681 aggctgtaca agctatcttt gaagcattgg atggagatga aggtcgtctg actgcttcta
    25741 atattgccga tagtatcggc atcactcgtt ctgtgatcgt caatgcttta cgaaaattgg
    25801 aatcagctgg aatcattgaa tctcgttcgt taggcatgaa gggaacttat ttaaaagtat
    25861 tgaattcccg ttttaaagac gagttagcaa aacacagtta ttagaagtaa ggggactggg
    25921 gcagatagaa atgtttgttc cagccttccc attttaaaaa gtaagtcgaa gttggaggaa
    25981 tggcaatgac tgttattatt caaaatgacc agctgatcgc cgaaatcgct gaacacggtg
    26041 cggaattgat cagtctgaaa tcaaaagaac atggtttaga gtatatctgg caaggtgatc
    26101 cagcgtattg gggcagacat gcaccggttt tattcccttt tgttggacgt ttaaaagatg
    26161 atcagtatgt ttatcaaggg aaaacatatc aaatggggca acacggattt gctcgggata
    26221 tggattttga agtcattgaa catggacaag aaatggctag tttcatctta aggagtacgc
    26281 cggagacatt agaaaagtat ccatttgatt ttgaattagt gatcagctat gaattaggag
    26341 gagacggcat cacggttcat tatcaagtgg caaataccgg tgaaaaagaa atgttctttt
    26401 ctatcggtgg acatcctgct ttcaatgtac ctcttgaaga aggattgtca tttgaagatt
    26461 tctatctggc attttctcca ttgaaatcaa gattacgcct accattgaaa ggcccattca
    26521 tcgatatgga tcaaaagacg ttaggtcaga caaatacgaa tctggctttg aatcgtgaac
    26581 tttttgagca agatgccttg gtttttgaaa caaggggtct aaatgcgtac gccattcgaa
    26641 gtgaaaaatc ttcccatagc gtaactttaa gctataaaga tatgccttat gtagggatct
    26701 ggtctcctta tccaaaagaa gcgcctttcg tttgtatcga accgtggtgc ggaatcgctg
    26761 acacggtgaa cagtagtgga aacttgatgg aaaaagtagg gatcaatcaa ctaggtgccc
    26821 atgaaatctt caagacaaaa tattccatca cagtgaagta agaggttgtg accgagaagt
    26881 tagcagggaa caccgtttac caaggtgtgt aaaaaagcta tcctgtaagt aataagggag
    26941 tgtgacatcg atttgtcaca ctcccgtttt atctctttgg aatgaaaaag tatcaggatt
    27001 ttttcttgct gctattcaaa ccaaacggga ttcgactttc agtatggttt ctgatacgct
    27061 tgatattgtc tttatgccga taaaagataa aggaagaaac taaaaaggca atgatcgtca
    27121 gtaaccaatt gggcttagcc aaaatcacag gagctacata aggaaggacg atcgtagata
    27181 aagtgatcaa tactgcactg atcatactgc tcaaactcac catacttgta caaaataaac
    27241 taacgataaa gatgatacaa gaataaacaa aaaatacagg attaaatcct aaaagcattc
    27301 ctgcacttgt cgcaacagct tttcctcctt tgaacccagc aaaaatcgga aatgtatggc
    27361 caagaatggc gcatacccca aaccaaagag ggttaatccc agaaaggtgg aagatcatcg
    27421 gcaaacaagt agccaatgta ccttttaaaa tatccataag caggacaaca atcccggctg
    27481 ttttgcctaa tacacgaaat gtattggtcg ttccagtatt accgctcccg tgttgtcgga
    27541 tatctttttt gaaaaacaat ttgccaatcc agacaccgga aggaatagaa cctaaaagat
    27601 atgctaaaat aagtaataag atcaatttca ttttttaccc tctttcaagt tgaaaactat
    27661 cctttatttt agcatgaata ggtaacagga acaattgaaa aaatgaaaga tacaagtata
    27721 atagatggaa taaaaagaaa agcaaggggt ggcagaaatg tctgtaaaaa atccaacaca
    27781 agaaacgatt ttcaactatt tggaagaagc aaaaaatatt gccgtcgtag gcttgagcaa
    27841 taaaccagaa cgaacaagtt acatggttgc acaggtattg caagacaatg gatataaaat
    27901 cataccagta aatccattat tggctggtga agaaattcta ggcgagaaag tctatgcgaa
    27961 tttgacagaa atcgatgatc caatcgatat cgtagatgta tttagacgga gtgaattttt
    28021 acctgaaata gcaggtgatt ttttgaaaac tgatgctaaa gtgttctggg cacaattagg
    28081 gattgaaaac aaagaagcag ctgagatgct aagaaaagca ggacgtacag atatcgtaat
    28141 ggatcgttgt attaagattg aacttggtaa gttgaaagaa aaccaaaaat aaaaatgacc
    28201 acaaagaaga gatgatcgat agaggggaat gtcgaaaaag cggttaggag ataattaaaa
    28261 ttgatttctc gtctaccctc ttttttttca cgaccttttc tagtatgata atcgtggtgc
    28321 ggttttgccg caaagtatta ttgaaggagc gtttgccttg gcaaaaaaag taaacaacga
    28381 atacaatgac tcgtccatcc aagtattgga aggattagag gcagttagaa aaagaccagg
    28441 gatgtacatt ggatccactg acagccgagg cttgcatcat ttagtctatg aaatcgtcga
    28501 taatgcagtt gacgaagcat tatcaggtta tggcagtgag attgatgtga ccatccatga
    28561 agacaatagt ataactgttg cagatagcgg acgtgggatg cctgtaggaa tgcatgcttc
    28621 cggaatacca acagttgaag tgatttttac tgtgctgcat gctggcggaa agtttggtca
    28681 aggagggtac aaaacttctg gtggactgca cggtgtagga gccagtgtgg taaatgcctt
    28741 atcgaaatgg ctaattgtaa cgatcgttag agatggcgta gagtatcagc agaaatttaa
    28801 aaacggcggt aaacctgacg gtactttgaa aaagatagga aaaacaaaaa aagcaaacgg
    28861 gacgactgtc cattttttac cagatgatac aatattcagt acaacgaaat tttcatatga
    28921 aattttagcc gaacggttaa gagaatctgc ctttcttcta aaaggcgtta aaatctctct
    28981 ttctgatctt cgtggagaag aaccagtcaa ggaaattttt cattacgaag aaggaatcaa
    29041 agaatttgtt gattatctga atgaagaaaa agatacattg acaccagttg tttatttttc
    29101 aggagaaaaa gaaggtatcg aagtagaggt cgcttatcaa tacaatgacg gttattcaga
    29161 aaatgtttta tcttttgtca ataacgttcg gacaaaagat gggggaaccc atgaagctgg
    29221 tatgaaagcg gcgatgacga aatcttataa tgaatatgcg agaaaagttg gtttgctgaa
    29281 agaacgggac aagaatctgg aaggtagtga tttcagagaa gggttagctg ctgtactttc
    29341 tatccgtgta cctgaaaatc ttctgcaatt tgaagggcaa acaaaagaaa aacttggtac
    29401 gccagttgct cgtaccgtag tagataacgt catcagtgaa caaatgggct tttatttgca
    29461 ggaaaatagc gaaatgagcc agatgttggt ccgtaaagca atcaaagcca gagaagcgag
    29521 agaagcagca cgtaaagcca gagaagaaag ccgaaatggg aagaagcgta aaaaaggcga
    29581 atctcttctt tcaggaaaat tgacacccgc acaatcccga aaccctaaga aaaatgaatt
    29641 gtatttagtc gaaggggatt ctgctggcgg atctgctaaa caaggaagag acagaaagtt
    29701 ccaagcaatt ctacctttac gaggaaaagt catcaatacc gaaaaagcta aaatgcaaga
    29761 tatcttgaaa aatgaagaaa tcaatacgat gatctatacg attggtgcag gagtcggtcc
    29821 tgagttttct atcgaagact gtaattacga caaagtaatc atcatgaccg atgcggatac
    29881 agacggcgcc catattcaag tattactgct tactttcttt tatcgttata tgaaaccgct
    29941 gattgaagct gggaaagtat atatcgcgtt accgccttta tataaagtat ccaaaggaca
    30001 aggaaagaag caagtcattg aatatgcgtg gacagatgac gaattggcag caatgattaa
    30061 aaaagtcggc aaaggatata tgctgcagcg atataaagga cttggagaga tgaatgcgga
    30121 acaattgtgg gaaacaacga tggatccgac ttcccgtacg ttgatccgcg tccgtatcga
    30181 tgatgctgcg caagctgaac gtcgagtaac cacactgatg ggtgacaaag tagaacctcg
    30241 aagaaaatgg atcgaaaatc acgtgcaatt tacgctcgaa gaagatggca gtatcttaga
    30301 taaaaaagag gatactgaaa tctctccttc agtttctaat gatttattag atgaagaacg
    30361 agcagataaa aatgaaaaca atcagttatt tgaagtagaa taggaggtca cctgatggaa
    30421 aatcgacaag aagtacaaga attaacttta gaagaagtga tgggtgaccg cttcggacgt
    30481 tattccaaat atattatcca agaacgtgca ctgcctgata tccgtgatgg attgaagcca
    30541 gtgcaacgcc ggatattatt tgccatgaac aaagatggca atacgtatga caaaggattc
    30601 cgtaaatcag caaaatctgt cggaaatatc atggggaatt atcatcctca tggtgacatc
    30661 agtatttatg aagcgatggt ccgcatgagc caagactgga agttgcggga agtactgatc
    30721 gaaatgcacg ggaataacgg gagtatggac ggtgatccac ctgctgcgat gcgttatact
    30781 gaagccagat tatccaagtt aagtggagag atgctagcag atatcgagaa agaaacagtc
    30841 gatctcgtgt ggaattttga tgatacagaa aaagaaccaa cagtccttcc agctcgatac
    30901 ccaaaccttc tcgtcaatgg atcgacaggt atatctgctg gatatgcaac agaaatcccg
    30961 actcataact tagctgaagt gatcgatggc acaatctata tgatcgatca tccacaagcg
    31021 agccttgaaa aattgatgga atatattcct ggacctgact ttccaacagg agggatcttg
    31081 caaggaaaag atgaaatcaa aaaagcttat gaaacaggac gaggaaaagt tattcttcgt
    31141 tcgaaaacaa agatagaggc aatgaagggt aataaacagc aaatcgtgat cacagaaatc
    31201 ccatatgaag taaataaagc gaccttggtg aaaaaaatgg atgagatccg tttgaataag
    31261 aaaatcgatg gaatagctga agtacgagat gaaagtgata gaacaggtct gcaaattgtc
    31321 gtcgaattga aaaaagacgc caatgctcaa ggaattttga attatttgtt caaaaacact
    31381 gagctacaga tcaattacaa tttcaatatg gtcgctatcg accatatgac tccgcatcaa
    31441 gttggactga aagacatttt aagaagttat atcgagcatc gaaagcaagt cataacaaaa
    31501 cgtagtcaat tcgatttagc caaagctcaa aaaagacagc atatcgtaga aggattgatg
    31561 aaagctttat cgattctgga tgaagtaatc gcaacgattc gtgaaagtaa agacaaaaaa
    31621 gacgccaaaa agaatttagt cgacgtcttt caatttacag aagaacaagc agaagcaatt
    31681 gtcacattgc aattataccg tttgacgaac acggatatca cagagcttca aaaggaatcc
    31741 gaaagcttga ttgcgcaaat cacagagttg aataaaatcc tttcaaatga caaagagctt
    31801 ttctctgtta tgaaaaaaga attgcgagaa gtgaaaaaaa attattcttc cgctcgtcta
    31861 acgacaatcg aagacgaaat cgaagaaatc aaaattgata cgcaagtctt agtggcacaa
    31921 gaagacgtaa ttgtcagtgt gacgcgagaa ggctatgtga agcgaacaag ccttcgttct
    31981 tatagtgctt ccaaaccaga agaaatcggg atgcgagaag gcgactactt gctatactca
    32041 ggtgaattga gtacattgga ccatgttctt ctgatcacaa ataaagcaaa tgtgatctac
    32101 cgccctgtcc atgaactacc cgatttgaaa tggaaagatg ctggtgagca catttctcaa
    32161 acaatctcca atctgtctgt agacgaatcg attttagctg ttttcccata tcaaaaaatt
    32221 caagcagaga aaacatttgt attcatcagc aagaatggat tgatcaagca aacacgaatg
    32281 acagagttcg aaccatggcg cacctataag agccgtccgc tcagctgtat gaagctaaag
    32341 gcggaagaag atgaactgat tgctgtgtat ctgaaagaag atcagccagg cttagatgtt
    32401 ttcttagtaa cgcatcaagg aatgggtttg cgctatcctt taacagatgt tcccgttgtt
    32461 ggagcaaagg cagctggagt gaagtctatg aatttgaaag atggagatag gattatcaac
    32521 gggctgcttg tgttagcaga aggtgatacg ccgatcgtaa tcgttactca gcgaggagct
    32581 gttaaacgca tgcttgctca agaaatcagc caaacttcac gtgcgaagcg gggagtgacg
    32641 gtcatgcgtg agctgaaaaa aaatccgcac cgtattatct atatgtcgga aggaagatca
    32701 aaagaaataa ccttgatgaa tcaaaaaggg cagcagttaa cgattgaccc aactgatttc
    32761 cctataggtg atcgaacatc gaatggatca tttgcgatgg atgagaaaaa aggtggagaa
    32821 gtcatcgaag ttatcgatgc tcctgagatt ttcatcgagt cgtaactgtt gtagtatttt
    32881 aatgaagaga cgccatctgt attaatacag gtggcgtctc tttttcattc atttttaata
    32941 aatccttata cgtttgcaaa aaaagatgaa agtgttcaca atgcttaaat gttggtatgt
    33001 caacgttgat ttaaatatat gtaaataaaa cataaaaatt gttaaataaa aaacaagaaa
    33061 acccttgcaa agatagggtg ctgtgttata ctaatcacgt aaaaactgtt acataaaaca
    33121 gaaatttagg aggtccatac aatggagcaa tggaatggat ttaaaggtac caaatggaaa
    33181 gaaggcgtag acactagaga ctttattcaa aataactaca ctgaatatcg cggtgatgac
    33241 agctttttgg aaggcccaac agaagcaaca gaaaaattat gggatgaatt gcaaaagtta
    33301 aatgatatcc aattcgagcg taacggtgtc tatgatatgg acacagaaat cgtatcaact
    33361 attacttcac acgatgcagg ctatttggat aaagatttgg aaaaaatcgt cggtctacag
    33421 acagacaaac ctttgaaaca agcattcatg ccgttcggcg gaatcaatat ggctaacaat
    33481 gcgctaaaaa gcaatggcta tacaccaaac gatgaattga cacatatttt cactgactgg
    33541 cgcaaaacac ataatcaagg tgtatttgac gcttatactg ctgaaatgcg tgctgctcgt
    33601 aaaaacaaaa tcattacagg gcttccagac gcttacggtc gcggacgtat catcggtgac
    33661 tatcgtcgtg tggcattgta tggaatcgac tatttgatgg aacaaaagaa aaaagatcat
    33721 gatatgactg gttatcatac aatgagtgaa gaagtgattc gtttacgtga agaaatcact
    33781 gaacaatatc gtgcattagc gcaaatgaaa gaaatggctg cgaaatatgg ctatgatatt
    33841 tctaaaccag ctgcaaatgc aaaagaagct gtccaatggc tatacttcgg atatttagca
    33901 gcaatcaaat cacaaaatgg tgctgcgatg tcaatcggac gtatctcagc attccttgat
    33961 atctatatcc aacgtgattt ggataatgga gtaatcacag aaaaagaagc acaagaattg
    34021 atcgaccact tagtaatgaa attacgtatg gtcaaattcg cgcgtacacc tgaatataac
    34081 caattattct caggattccc tatctgggct actttatcca ttgcaggtat gggattagat
    34141 ggtcgttcat tagttacaaa gaatgatttc cgtctgcttc atacattaac aaatatggga
    34201 ccttcaccag aaccaaactt gactgttttg tattctgaac accttccaga aggattcaga
    34261 acatatgcta gcagaatcgc tatcgaaagt tcttcgattc aattcgaaaa tgataatcag
    34321 cttcgtgaac aatggggttc tgatgattgt gcgattgctt gctgtgtatc aggaacagtt
    34381 gtcggaaaag acatgcaatt ctttggcgct cgtgctaact tggctaaaac actattatat
    34441 gccatcaatg gcggagtcga tgaagtgact ggcgcccaag ttggaccaga atatcgtcca
    34501 atcacatcag aaatactaga ctttgaagaa gtgaaacata acttcatgaa tatgatggat
    34561 tggttagcag aactatatgt caatacgttg aacatcattc attatatgca tgataaatat
    34621 tcttatgaag cagctcagct ggctttgatg gattctgact tgcaacgcac atttgctaca
    34681 ggtattgctg ggatctctca tgcggcagac agcttgtcag cgatcaaata tgcaaaagta
    34741 aaagcaatcc gtaatgaaaa aggaatagca gttgattttg aagtggatgg cgacttccct
    34801 aaatacggaa atgatgatga ccgtgcagat gaattagttt catggatctt ggaatacttc
    34861 atgggacaaa tcaaacgtca taaaacttac cgcaactcaa aaccaacaac ttcattattg
    34921 acgattactt caaatgttgt ttacggtaaa aatacaggaa atactcctga tggccgtgaa
    34981 gctggaaaac cacttgcgcc aggagcaaat ccaagttaca atgcggaaca aagtgggtta
    35041 ttagctagcc tgaactcaac agctaaaatg aattacggct gtgcattgga tggaatttca
    35101 aatacccaaa caatcaatcc ttcaggtctt ggaaaagaac aagatacaag aatcgaaaac
    35161 ttgcgtaatg tcttagatgg atacttctca aaaggagctt atcatttgaa tgtcaatgta
    35221 ttcagtaatg atttattgcg tgatgcaatg gaaaatccaa tgaaatatcc gaacttgacg
    35281 atccgggtat ctggttatgc agttaaattc cgtgacttga caagagaaca acaattagat
    35341 gtcttgatga gaacttcaca cgacagaatg taaaaagttc gtgaaaaaag tttttcgact
    35401 tagcgtcgaa aggacgttga atagccatcg catcaaaatc gaataatcag tatgcttatt
    35461 tgaaagaaac gatttacagg ggcaggactt gtatgttccg tccctgtaaa ttttacacat
    35521 aacgaagcgg caattgcgaa aaattttgtt cagaaagctt cgcttcgaca gctaacttgt
    35581 acttaaaatg aaatcaaaga aaagatgtga acttaaatgg aagaaaaaac aatcggctat
    35641 gttcattcta tcgaaacttt cggttcagta gacggacctg gactgcgctt tgtcgtgttt
    35701 atgcaaggat gccgcatgcg ttgccaattt tgtcacaatc cagatacttg gaatattggc
    35761 ggagggaaag aatacacagc agatgaactt ttagataaag cagaacgctt cagaccttac
    35821 tggggagata aaggtggtat tactgttagt ggtggagaac ctctattgca gatcgatttt
    35881 ttgatcgaac tatttaaaaa agcaaaagag cggaagatgc atactacatt ggatacatgc
    35941 ggaaaacctt ttacgtatga agaacctttc ttttcacgtt ttcaagaatt gatgaagtat
    36001 acagatttac tgttatttga catcaaacac atcgataatg aagagcataa aaaactaacg
    36061 cattgggaca atgaaaatat tttagaaatg gctcaatatt tgtcaaaaat caacaaaccg
    36121 gtttggattc gccatgtact agttcctgag cgaagtgatt atgatgaata tttgatccga
    36181 ctagacaact ttattcaaac cttgtcaaat gtagacagag tagagattct tccttatcat
    36241 acgatgggaa aatacaagtg ggaaacactt ggtttgaaat atccattaga agggatcgaa
    36301 ccacctacaa aagaacgtgt cgaaaatgct aaacgattgc ttcatacaga agagtataca
    36361 aaatatttaa cgcgataggt cgcatcggaa agaagataag
//
LOCUS       DBBGSZ010000025        36161 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.025, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000025 DBBGSZ010000000
VERSION     DBBGSZ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 36161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36161
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.025"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..1008)
                     /locus_tag="ACIZE5_001718"
     CDS             complement(<1..1008)
                     /locus_tag="ACIZE5_001718"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGC6108846.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1188..1532)
                     /locus_tag="ACIZE5_001719"
     CDS             complement(1188..1532)
                     /locus_tag="ACIZE5_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGC6108847.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1525..1959)
                     /locus_tag="ACIZE5_001720"
     CDS             complement(1525..1959)
                     /locus_tag="ACIZE5_001720"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGC6108848.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2097..2834
                     /locus_tag="ACIZE5_001721"
     CDS             2097..2834
                     /locus_tag="ACIZE5_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6108849.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            2827..4038
                     /locus_tag="ACIZE5_001722"
     CDS             2827..4038
                     /locus_tag="ACIZE5_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6108850.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4242..5024
                     /locus_tag="ACIZE5_001723"
     CDS             4242..5024
                     /locus_tag="ACIZE5_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HGC6108851.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5094..5756
                     /gene="trmB"
                     /locus_tag="ACIZE5_001724"
     CDS             5094..5756
                     /gene="trmB"
                     /locus_tag="ACIZE5_001724"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HGC6108852.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(5854..7608)
                     /gene="ade"
                     /locus_tag="ACIZE5_001725"
     CDS             complement(5854..7608)
                     /gene="ade"
                     /locus_tag="ACIZE5_001725"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HGC6108853.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            7740..8669
                     /gene="comGA"
                     /locus_tag="ACIZE5_001726"
     CDS             7740..8669
                     /gene="comGA"
                     /locus_tag="ACIZE5_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HGC6108854.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            8626..9675
                     /gene="comGB"
                     /locus_tag="ACIZE5_001727"
     CDS             8626..9675
                     /gene="comGB"
                     /locus_tag="ACIZE5_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HGC6108855.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            9672..9950
                     /gene="comGC"
                     /locus_tag="ACIZE5_001728"
     CDS             9672..9950
                     /gene="comGC"
                     /locus_tag="ACIZE5_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HGC6108856.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            9925..10395
                     /gene="comGD"
                     /locus_tag="ACIZE5_001729"
     CDS             9925..10395
                     /gene="comGD"
                     /locus_tag="ACIZE5_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HGC6108857.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10367..10714
                     /locus_tag="ACIZE5_001730"
     CDS             10367..10714
                     /locus_tag="ACIZE5_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108858.1"
                     /translation="MVAIQKELNKTGFVLLESLTALMIASVCVYLVSFGQLFLLQAEK
                     KSGEELLFIRMIYEDIKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAI
                     SIEKTSNSSIYAD"
     gene            10677..11102
                     /gene="comGF"
                     /locus_tag="ACIZE5_001731"
     CDS             10677..11102
                     /gene="comGF"
                     /locus_tag="ACIZE5_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HGC6108859.1"
                     /translation="MKKQVIPAFTLIECLIGLMILSSLLLTFNLLIQQTIQVSEFLQR
                     KDQKEWLIFLAQLEEELKSSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQ
                     PMLTSITELQLLEKEHTISFYVHFENGEDGYAIWTKNDQ"
     gene            11074..11433
                     /gene="comGG"
                     /locus_tag="ACIZE5_001732"
     CDS             11074..11433
                     /gene="comGG"
                     /locus_tag="ACIZE5_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HGC6108860.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            11605..12612
                     /locus_tag="ACIZE5_001733"
     CDS             11605..12612
                     /locus_tag="ACIZE5_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC6108861.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            12637..13821
                     /locus_tag="ACIZE5_001734"
     CDS             12637..13821
                     /locus_tag="ACIZE5_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HGC6108862.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14258..15841)
                     /gene="abc-f"
                     /locus_tag="ACIZE5_001735"
     CDS             complement(14258..15841)
                     /gene="abc-f"
                     /locus_tag="ACIZE5_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="HGC6108863.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(15946..16074)
                     /locus_tag="ACIZE5_001736"
     CDS             complement(15946..16074)
                     /locus_tag="ACIZE5_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108864.1"
                     /translation="MMRMTKITSNENYQRYHIAFSHAIGFTVAVDGTSLSKTVEFT"
     gene            complement(16419..16562)
                     /locus_tag="ACIZE5_001737"
     CDS             complement(16419..16562)
                     /locus_tag="ACIZE5_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HGC6108865.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(16785..17264)
                     /locus_tag="ACIZE5_001738"
     CDS             complement(16785..17264)
                     /locus_tag="ACIZE5_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGC6108866.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17337..17621)
                     /locus_tag="ACIZE5_001739"
     CDS             complement(17337..17621)
                     /locus_tag="ACIZE5_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108867.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(17699..17893)
                     /gene="ssrS"
                     /locus_tag="ACIZE5_001740"
     ncRNA           complement(17699..17893)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACIZE5_001740"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(17965..19251)
                     /locus_tag="ACIZE5_001741"
     CDS             complement(17965..19251)
                     /locus_tag="ACIZE5_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HGC6108868.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19389..20060
                     /locus_tag="ACIZE5_001742"
     CDS             19389..20060
                     /locus_tag="ACIZE5_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HGC6108869.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20026..20514
                     /locus_tag="ACIZE5_001743"
     CDS             20026..20514
                     /locus_tag="ACIZE5_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HGC6108870.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20527..21474
                     /gene="prmA"
                     /locus_tag="ACIZE5_001744"
     CDS             20527..21474
                     /gene="prmA"
                     /locus_tag="ACIZE5_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HGC6108871.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21475..22239
                     /locus_tag="ACIZE5_001745"
     CDS             21475..22239
                     /locus_tag="ACIZE5_001745"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HGC6108872.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22472..24685
                     /locus_tag="ACIZE5_001746"
     CDS             22472..24685
                     /locus_tag="ACIZE5_001746"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HGC6108873.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            24696..25142
                     /gene="dtd"
                     /locus_tag="ACIZE5_001747"
     CDS             24696..25142
                     /gene="dtd"
                     /locus_tag="ACIZE5_001747"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HGC6108874.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25313..26572
                     /locus_tag="ACIZE5_001748"
     CDS             25313..26572
                     /locus_tag="ACIZE5_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HGC6108875.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(26661..27608)
                     /locus_tag="ACIZE5_001749"
     CDS             complement(26661..27608)
                     /locus_tag="ACIZE5_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGC6108876.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28002..29294
                     /gene="hisS"
                     /locus_tag="ACIZE5_001750"
     CDS             28002..29294
                     /gene="hisS"
                     /locus_tag="ACIZE5_001750"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HGC6108877.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29309..31078
                     /gene="aspS"
                     /locus_tag="ACIZE5_001751"
     CDS             29309..31078
                     /gene="aspS"
                     /locus_tag="ACIZE5_001751"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HGC6108878.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31187..32062
                     /locus_tag="ACIZE5_001752"
     CDS             31187..32062
                     /locus_tag="ACIZE5_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGC6108879.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32328..34211
                     /locus_tag="ACIZE5_001753"
     CDS             32328..34211
                     /locus_tag="ACIZE5_001753"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGC6108880.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34286..34570)
                     /locus_tag="ACIZE5_001754"
     CDS             complement(34286..34570)
                     /locus_tag="ACIZE5_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGC6108881.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34560..35294)
                     /locus_tag="ACIZE5_001755"
     CDS             complement(34560..35294)
                     /locus_tag="ACIZE5_001755"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HGC6108882.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35423..36046
                     /locus_tag="ACIZE5_001756"
     CDS             35423..36046
                     /locus_tag="ACIZE5_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HGC6108883.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
BASE COUNT        11268 a         6455 c         7605 g        10833 t
ORIGIN      
        1 ttttgatgaa tcagttgttt cttcagttga agattctttt gttgaatcag ttgattttgt
       61 gtcagaactc tttgttgaag ctgtagtttc acttgagtct ttcgtacttg atgaagttgt
      121 tgtgaatgca ctcaacacat tttcaaaggc atcatctttg atttttacat ttgcatcttt
      181 taattcttca ccgattactt tagttgtgaa tgcattgtca cttagtttag tttcagtagc
      241 gatatctttt agttgatctt tgtatttatc catgtcattg cctttatttt ggtttttcac
      301 cattttgaca acgtagtatt ctgtcgcata agaagtagga tttgttgtag taataacatc
      361 ggagatctca ccgtctttca atttgaaagc tgcttctttt acttctgcag gaatagttgt
      421 tgtcgttgag tcgaatttaa ctttaccgcc atcttctttt gtctctgtat cagttgattt
      481 gtctttggct aatttagaga aatcatctcc atcatccgct gattttttca catcttttgc
      541 ttcatcttca cttgataatt tgatgatttg tgcttctact tctggatgga aagatttcca
      601 agcagttttc aaatcgtcat ctgtaatatc tacgtgagct ttcaagccag cttcaaaagc
      661 taaattgtta cgaatatatt ctttataagt atctttcgta tatccagcag cttctaattg
      721 tgattcaaaa gtatcaccta atgatttcgc ttgtttgtcg tattctgcat ccacttgctt
      781 atcggttact ttatcgccat atttgttatt gaatacttta taaatgatca tccgttgtac
      841 taaggattgg ttcgatgatt caagttttgc ttcatcatag aaatcagata cagtgatcgt
      901 tccgcctttc atcgttgcga tatctttatt agtatcgcct gaacaagctg ctagagttaa
      961 aacagccaac gcactagtag ctgccaaaat aattgatttt tttttcatta aaatttgcac
     1021 tcctgtaatt agttattatt tttatatatt aactatacca tatcccattt cctttaaaaa
     1081 cgttgtcgtg gtagtttcaa acaaaattca aaatttcatc acattcctag gaaatacgca
     1141 aacttttctc acttatatag ttaaatctgt tgagaaaata atcattatta tatttgttca
     1201 ggatactctg gcagatcagc ttttagtttt tctacttgtt cattgatttg tgtgatacgt
     1261 ggttcggctt ggaatttaaa atcttcgata tcttttttga ttgcttcttg gaaagcagga
     1321 atcacagatt cagctgtttc ttttgtttcg atcaatgcgc ttttaaaatg attcaggctg
     1381 ttatttaaat catttgtcag agttgttgct tcttccaatt cttcgatcag tttctttctt
     1441 gtttcattcc cgctcctggg cgccaataac agacctccga cagtgccagc agcagctcca
     1501 aataacagtc ctttgaaaaa gtttttaatc atcgcaggac acctgcttta cgattgtttc
     1561 ttgaatagct tttagttctt ccgatccata actatcttga tgattgacaa agtgaataga
     1621 aaaatcatcc tctttgctgt agcgagggac taaatggata tgtgaatgaa aaacagattg
     1681 ataggctagt tcacggttgt tattcaagat attaagacct ttcatttctg gaaaagcttt
     1741 ttccaatgct tgagcaatct taggcacacg cgaaaaaacc tctcctgcaa gttcgggatc
     1801 atattcaaaa atatctgcta catgacgttt aggcacaact aatgtgtgtc ctttcgttgc
     1861 ttgagagatg tctaaaaaag catagacctt gtcgtcttca tatattttat agcttgggat
     1921 ttcttgattg atgattttgc aaaaaataca gttttccata taaaacatcc tttctataaa
     1981 gaataaatac ttcagcttaa ctttaccata agttaaagct attgtaagga aaaaaacaaa
     2041 ataccgtcat tttcttcgtg gtataataaa taaaaataaa tggcggagga aaaagaatga
     2101 gtttaattat cgatcatgtc acaggggggt acggacatct ccctgtgtta aaagatatca
     2161 gtttcgatgt acagcctgga gagatagtag ggttgattgg actgaacgga gcagggaaaa
     2221 gtacgaccat caagcacatt atcggtctgc tggaagcttc aaaaggaacg atagaaatca
     2281 atcatctatc cttaaagaaa aatacggaag aatatcgcaa acaaattggg tatattccag
     2341 agactccttc tttatatgaa gaattgacat tgagagaaca tatcgaagtc actgcgatgg
     2401 cctacgatat acctatggat atagcaatga aaagagcaga aaagttgttg gagacttttc
     2461 ggttatctaa tcgtcttgac tggttcccag ctaatttttc aaagggaatg aaacagaaag
     2521 tgatgatctt atgcgccttt ttgatcgagc cttctttata tatcatcgac gaaccatttt
     2581 taggcttgga tccactagct atcaatgcat tgcttgaatt gatggtagaa atgaaaaaag
     2641 aaggagccgg tattttgatg tctacgcata ttttagctac tgcagaaaaa tattgtgatc
     2701 gttttgtggt cttacataac ggagagatac gagcagacgg ttctcttgag atgttgagaa
     2761 aagaatttca gctgccggat tcttctttgg acgaaatcta tattgcttta acaaaggagc
     2821 aggcacatga gtagtttttt tcaaaaacgt ttagcaagac atcaaaagaa aatgatgaaa
     2881 tatatgcgtt atgtattgaa cgatcatttt gttttagttt gtcttttctt gattggcggt
     2941 gtgggattat attattctaa ttggttgaaa accctgcagc caccgtttgc aattggaggg
     3001 ctcataatct ctgtattttg gatgctctgt ttattcgtgg gtaagatggc tacttttgca
     3061 gaggcagcag atattgtttt tttacttcct aaagaaaaag aaatgcaaac ctatttggaa
     3121 cgagcttttc gctattcttg catttttccg ttgatctttt tgatattggc atgcggattg
     3181 gccatgccat tagtggtggt tagtacggag caatcctttt cgatgttttt cgtctatctg
     3241 atcatattat ggagtttgaa attcagtcat ctgcaaatca agagagcaga attgtttcga
     3301 ctagatcaac aagttattcg ttattggaaa ttaggctggt ttttttcttc tctgatcttt
     3361 ttgtttctat cattttattg gctaatatgg gcaggaatag caggtgcatt agtacaggca
     3421 agtctatatt actggttttt gtggaagcaa caagaaaaag gattggattg ggagaaaatg
     3481 gtgcatgtag aagaacatag gttgcatcag atctatcaat ttatcaattt attcacagat
     3541 gttcctgaaa ttacggcaaa gatcaaaaga agacgctatt tggatcctat attgactcat
     3601 attaaaagag aatcaaaaaa cacttatctt tacttgtttg caagaagatt ggcaagaggt
     3661 tctgatttta gtggtcttta tttccgatta gtaattatag gtgggttatt gattgccgga
     3721 gtagtcgact tttattttag tctgattatc ggtttcttat ttttatattt gatcggtttc
     3781 caactgttac ctttagcgaa ccagttccgc tatatggttc tcgttcagct ttatccaatc
     3841 cataagaatc agaagaagca ggcgattcag tatctactca catgggtatt aattatcgcg
     3901 tcggttattt ttggtttgat tgctgcagtc gtattagatg ggcagcagcg atgggttccg
     3961 ctagcggctt atttgattgt tactatgctc tttgttaaac tatatgtacc aactcgtttg
     4021 aagaagatgt cagactgaaa acaaagctgt gtagggtaaa aatgagaatg aaaaatagag
     4081 cgttgacagt aagaatgctg ttcgttctat tttttttgag aaaagctggt tttttgaatg
     4141 gcaattaaat gaaaaagaac gtatatgtgc ttgacgtgta gtgttcaggc gactagaata
     4201 ataagtactg caaaacaaag agtaagagga cgggagaatg catgatggag tttcagttag
     4261 accaagagtg gcggttacgt cccatcaaag gcgacacagg aaaaacatac ataggcatgc
     4321 gtgatgagga caaagtcttt attaaacgaa acacgactcc gatgttggct gctctttcaa
     4381 gggaaggaat tacaccaaaa cttgtttgga caaaacgaac ggggaatggc gatactttga
     4441 cagcacaaga gtggctggaa ggtcgcttgc tgactcctaa tgagattggt caaagaaacg
     4501 acgtgattga tgttttgtac catttacatc attcaaattc tcttaaaacc atgctgaccc
     4561 gtatcggtgg tcgtgtcatg acgccggaga agatgctgca aaaatatgaa aaagaattac
     4621 cggaagaact ccagaaaaat caatttctgc aaattgtcca tcgttttctt cgtgagcaga
     4681 tcccgtcaat agataaggaa aacttatcag tagtacacgg agatgtaaac catcgtaatt
     4741 ggttagtatg taaaaattat ttatatctag tcgattggga ttcaatcatg tttgcagacc
     4801 ctgcggtgga tattgcaacg attttaggaa attatgtgcc actgtctagc tggaatcagt
     4861 ggctgatcag ttatggcata cgcccgactg acgaaatgct tgaaaaattt cattggtatg
     4921 cggccatgaa tttgctccaa gaaatcacca gatattgcaa acgtgaagat catcgacgga
     4981 tgaacgaaga aattttacaa ttaaaacgaa ttttcagtgg ctgaggtttg gcccaaactc
     5041 tgcggagatt tggccagacc tttttaatta gaggaaagga atggagataa ataatgcgtg
     5101 tccgaaatcg tccgggagca gcggaaatgt tagcggctca cccgaatttt gtaattagtg
     5161 atccaacatt gtggaaggga aaatggaatg aattgtttga aaacgatcat ccaatccaca
     5221 ttgagattgg tatggggaaa ggccagttca tcactggaat ggcaaaagcc catcctgaaa
     5281 tcaattatat tggagtagaa atgcaggtca gtgttgtttc gattgcacta gacaagttga
     5341 tcgaacaacc gcttcctaac ctgaaacttc tacatgtgga tggatcagcg ttgacagagt
     5401 atttcgctga cagcgaagta gatcaaatct atctgaattt ttccgatcca tggccaaaaa
     5461 aacgtcatga aaaacggcga ttgacatata agacttttct tgctgtagat gaacagattc
     5521 ttcgtccaaa tggagaaatc catttcaaaa cagataatca aggattgttt gagtattctc
     5581 tggcaagttt ttctcaatat ggcatgatcc tcaaacaggt atggttagat ttacatcaaa
     5641 gtcaatttga aggcaatatt atgacggagt atgaagaaaa attttcttca aaaggtcaac
     5701 gtatttatcg agtagaagct caatttcaag ataagaccaa aaagaaaagt ctgtgaaact
     5761 aactttctgc tttcataaaa acattaatat ccataaataa atcccagaaa atgaacatta
     5821 cagatgtaat gtattttctg ggatttattt gatttaaaat gtatttattt catcggtttt
     5881 tccacaaggt ggaatcaatt ggaagcgaga aaatgaaaat aatcctttgt cggtgatctt
     5941 caattcgggt atgacagata atgttaagaa agaaagtgtc aaaaaaggat caaaggtttt
     6001 agctgctcct agttgatgtg ctttagttat taattcattc aactgttcat agacgatcga
     6061 aaaaggttcc tgtgtcatga ttccgcctat aggaagagaa acacaagcta tttcctgctg
     6121 attgttgaca acggtcatcc cgccaccttt ttgaatcaaa agattagcag catacagcat
     6181 atcctcgtcg tttgtcccaa cgacaactag attatgcgag tcatgggcaa tcgttgtcgc
     6241 tatcgctcct tgtttcagct gaaatccttt cactatgcct aatccaatgt ttcccgtttg
     6301 atggtgacgc tcgatcaccg caatctttaa ttggtctttt tcgattgaag gaatgaatcg
     6361 ttcgccttgt cggtccactt tttctaccaa atctttagtc actagactat tcgggataat
     6421 ttcgatcaca tgggcttgtg aagaagaaag aagcagctct aacgaatgtg gatttaatgg
     6481 ttgagcgttt agttttggca gacaacacgt atatgaattt gaatgatcag caaataaatg
     6541 gtcttggagt tgcccagatt gaacaactaa tgttccctta tagaaaactt catgaattgg
     6601 cagcttggta agatcgtctg ttaagaagaa atcagcttga tacccagggg caatcgcacc
     6661 tagtgttttc aaatcaaaac attctgctgc attcaatgtt gccatctgaa tggcttgtaa
     6721 tggatcgatt ccaagtgcaa tagcttgacg gacgatatga tcgattgatc cttcttttac
     6781 taaatcattg atcagtttat catcggtgac aaagaagcat cttcttgaat tttcaggtgt
     6841 gatcgccggt agtagcgatg ccagatcttt tgcaacggtc ccttctcgaa ccattaaata
     6901 cataccaaga tccaaacgtt ctttagcttc ttttgcagtt gtagcttcat gatccgtccg
     6961 aatacctgct gcaggataaa catttaactc ttccatgccg ataccagctg catgcccgtc
     7021 aatttttttc ttatgctggt gcatcaattg gatcttttct aggatgtctg tttcattatt
     7081 tgctactgct tgatagttca tgacttcagc taagcctaaa acttcgggtt tttgtaaaaa
     7141 aggggctaat ttttttgcat ttaaatttgc accattggtc tcaaaagggg ttacaggtac
     7201 acaagaaggt agcataaaaa agatattcat gagtgtttgt cttgcatctt ctatcataaa
     7261 ctcaagacct gtactcccag caatgtttcc tatttcatgg ggatctgtca ctacagtagt
     7321 aactccatga agcaaggata cttttgaaaa ttcgcttggt gataaaagtg agctttcgat
     7381 atgcacatgg ccatcgatga atcctggcac tagatattgc ccattagcat tatgtacgct
     7441 ttttccttcg tattcaccga ttcctacgat cattccttcg cagattgcta catctttttc
     7501 catgatttct ttcgtaaaga cgttgacgat cttagcatgc ttgatcacta ggtcagcagg
     7561 ctttttttta cttgctactt cgatatattt ccttaatgtt gtttccaatg gagtgcctcc
     7621 caagataaat ttttataagt ataacataaa ttcggttttt gccaatattt ttttgtaaat
     7681 tcattttatt tgaaacaaaa agatcaaaaa gacgtatgtt ttttgtggag gggagaataa
     7741 tggaaataaa acgattatcg gatcaaatga taagtgaaag ttttgccaaa catgcccaag
     7801 acgtatatat attgccagct tcagaagtat tttacatcta ttttcgctat ggaaaaaaac
     7861 gaacattctg gaagaaagtc tcttcggcag atggacagca actgatctca agatttaagt
     7921 atttgggaca gatggatatc ggagaaaaaa gaaaagctca gttaggtgca tttacttatt
     7981 ctttagaaaa acaggaagtt cgtctgcggt tgtcttctgt aggagattac cttcaacgag
     8041 agagtttagt gattcggcta ttatacggta cttttgaaac accccatcgt tgctttagtt
     8101 ctcgagattt tgcaactatt ttacagaaaa ccgtcagacg tggattatac cttttcagcg
     8161 gaccagtcgg atcaggcaag acttctctaa tgtatcggtt ggctttggaa gaaaaattgc
     8221 aagtgattac tatcgaagat cctgtagaga tagaagaacc gttttttctg cagctacaga
     8281 tcaatccgaa aatagcacag acttatgata cacttttgag actcgcatta cggcatcgtc
     8341 cagacttgct aatcattggc gagataagag atgaatcaac tgcacatgct gcggtaagag
     8401 cagcactaac agggcaccgg gtttttgcaa ccgtacatgc acgcaatctt gaaggtacat
     8461 tggtcagaat ccatgaactg acaaagaaaa aagaagagct atctgaatgt ttagctggtg
     8521 tcatttatca agaacttttg gaagatgcca atcaccatcc ttctgtttta tggagttatc
     8581 aatttatgga ggaagaatca gtaaaaaaat catgggagga aagttatgaa gaagctcagg
     8641 aaaatatttg gcagtcagaa ctattctaaa ggattaacaa gaagccagca aaaccagttt
     8701 gcacaaacca tgggagaact gcttttatct ggttttagtc tgcaagaatc cctttattta
     8761 ttactcacga tccgttcgtt tccacctgtt attttggcaa atatccaaca tcagctaaag
     8821 gaagggcaag cgtttagtga ggtactttcg caaataggat atggagcaga gcaactggta
     8881 cagatcgagt tagctgaacg tcatgggaat ctgccgacaa ctttgttgga aattgccaaa
     8941 cagtttcggc ttgttgaagg atttcgcaat gatttgaaaa agctgcttgc atatccgatg
     9001 ctattgctca cctttttgct aggtatcttg tttagtatgc ggttgttcgt tttgcctcag
     9061 cttattggtt caggaatggt catgcaagag cattggggta ttcagctgat acaagtcttt
     9121 cattggtatg ttctactatt catcctagcg gttactctat tggctttact agtaaggtat
     9181 cgtctgatga agttgtctcc tgttgatcag agtgaatgga taagcagaca attattgatt
     9241 ggaccgatat attccttgta tcaatcggct tatttgtcac tagagattgg aaagcttttt
     9301 catgaaggtt tcgaattaag gcaaatcata gtctgcttaa aggaaacgaa acaagaaagt
     9361 ctgattcagc atcttgcctc taagttgatt caaggattgg aggcaggtat gtcattggct
     9421 gagcagttcc agaattatcg ttttctatca gaagaattca gtaaaattgt tttacaggga
     9481 gaggcaaagg gaagtttagg taaagaactg attttttaca gcgaatggac aagaaaacag
     9541 cttttcaaac gtcttcatca ctggatgcat tttattcagc caatcatttt tttgggcgta
     9601 gcggctttga ttttattagt ttatgccgct gttttattac ctgtttacgg aagcatagag
     9661 gaggttttgc catgaaaaag agaaaaatat cttattatag cggttttaca ttgatcgaaa
     9721 tgctaatcgt cttactgatc atcagtgtat tagtgttgtt gttcgtccct aatttgtcgc
     9781 gttataggaa tcatgtagac caagaaagtc gtgaagcgat catccagttg gtagacacac
     9841 aaaaagagct ctatgcgctt caaaataatg gaagagttcc tactgtggag gaattgttga
     9901 atgaaggcta tatcaaacga gaacatgcag aaatctatca gcggccttga aggtaaggtt
     9961 ttagcatcag gatatacgtt gtttgaatca ctcttactga ttttattact tacaacgatc
    10021 ctttcttttc cagttctcgc attttctgca tggaagaatg aattggcagt ctatcaattt
    10081 ttcggccaat ttgaaaaacg aatctattct acgcaaaaaa tcgctattgt gaatcagatc
    10141 caaacaggct tttattggaa tagtgaagag aatcaaatca tttttcatgt tccgaatcca
    10201 gataaaataa attgggaagt attagatatt cctgatgaga ttaccttgaa acgccatgct
    10261 tctattactt ttgctgctag aaccgggaat gaaagttcac taaaagctta tcaattttat
    10321 tgggaagaaa aagagcggac gattacgtat caattccaga tagggagtgg tcgctataca
    10381 aaaagaattg aataaaacag gatttgtttt gttggagtcc cttacagcgc ttatgatcgc
    10441 ttctgtctgt gtctacttag tgagctttgg ccagctgttt ttgcttcagg cagaaaagaa
    10501 aagtggggag gaactgctat ttattcgaat gatttatgaa gatatcaaga cgcagcggat
    10561 gtatcacaaa agaccagagc gaagggaaga aatgatccca tacgatatcc aaattgtcga
    10621 taataatgga gtaatcgaaa aagtgtttgt caatatggag aaagaagcga tcagtattga
    10681 aaaaacaagt aattccagca tttacgctga ttgaatgtct aattggactg atgatattga
    10741 gcagtctatt gctcacattc aatcttttga ttcagcaaac catccaagta agtgaatttt
    10801 tgcagcgtaa agatcaaaaa gagtggctaa tatttttagc acaattagaa gaagaactca
    10861 agagcagtca caatgtctct gtgaaaaatc agcaactgca ctacacgatc gaggataaac
    10921 agtatatcat cgaaagatat caggcaatga tacgtaaaag aagaacttcc ggcggacatc
    10981 aacctatgtt aacaagtatc actgagcttc aattattgga aaaagaacac acaatttctt
    11041 tttatgtaca ctttgaaaat ggagaagatg gatatgccat atggacaaaa aacgatcagt
    11101 agaaaatgtt ataagggctc tattttattt tctgtcttgc ttttatttct tttatgtacg
    11161 tttttattga tggcagcatt agaaagctac cgtttgtcaa tggatcttaa tatacgaatc
    11221 aaaaattatt atatagcaaa aataatgaag cagatggctt tatcggaaca gtctacgctt
    11281 gccgaaagtt cggaaggagt tttttactac acaactggat ctgtaacata tcagtgggta
    11341 caacagtccc tattcttaga ggtggaagtc tcaccgttta tctttcggtt cacagaagaa
    11401 gtaaaaaatg atacagatac tagtacagaa tgatggaatg ttcgtgaaaa cgccctcttt
    11461 tctgttataa cactgttttt aataaaaaaa tgtttgccgt ttcacaaata aaaaacagtg
    11521 aaaacgattg aaattttgtc aattgttcga tagaattaaa caggtgaaaa aattgttata
    11581 atatatctag aaatgaggtg caccatgtta ccagaaaaaa tggaacaagg gtttaatcaa
    11641 aacctggaag ctattcagct tttacagaat gcattgggaa cttccttttt agaagcctat
    11701 gtcgaaaatg cagaaaattt aatagatgat tatcaagtac gtgtggtgga tggagtgccg
    11761 acaaaagaga caacgcaacg gatcacagct ctttatgaag agttgaagaa actttctttc
    11821 gagccagaag aatggcgcag actgtctcaa ttacttttat tgaagggcag ccagacagaa
    11881 catttgcagg cgaaccatca actcactcct gatagtatcg gttttttatt tgtttttctt
    11941 attgaacaac tatacacaaa taaaaaagca ccggttaaga ttctggatat tgcggcagga
    12001 atgggcaact tgttattaac agttctttta aacctatcga atgcggggta ccaaacagaa
    12061 ggaattggtg tggatattga tgatacattg ttggctgtcg cagcttctac aagtgatttg
    12121 acacaagcaa atgttcaata ctttcatcaa gacgggttgc aggaattatt aatagatcct
    12181 gtcgattttg caatcagcga tttgccaatc ggttattatc cgaatgacga aaaagcaaaa
    12241 gagtttttaa caagtaccga agaaggccat agttatgcac atcatttatt gctagagcaa
    12301 tcaatgaaat atgtgaagcc ggatggtttt ggtttgtttt tgatgccgag tggattttta
    12361 gaaacggatc aaagtgaaga aatcaaaaaa tggtttaaag aagaaggtta tcttcaagga
    12421 atgattcaat tgccagatga attgttccgt aataaacaat cgcaaaaaag tattttgatc
    12481 ttacagaaaa aaggaccaca agcacaacaa gtaaaagaag tcttgcttgt gaaacttgct
    12541 tcattaaaag aaccagagaa ggtgacggaa tttttcaacg agtttaaaaa ctggaaatca
    12601 tctgctctgt aatcattcaa cgagaaggag agtcatatgt ctaaaacaat tgcaatcaat
    12661 gctgggagtt caagtttgaa atggcaatta tatcaaatgc cagaagaaac cgtagttgcg
    12721 aaagggatcg tcgaacgtat cggtttacaa gattctattt ttaccatcaa gtacggcgat
    12781 aatcaaaaat tcgaacaaat catggatatc gaaaaccacg aagtagcagt aaaaatgctg
    12841 ttagatcagt tgattgaact gcaaatttta agctcttatg atgaaatcac cggagtaggg
    12901 caccgtgttg ttcacggagg agaaacttat ggggattcag tagtgatcga tgagaaagta
    12961 atggaccgca ttgctgaatt agcagaattt gctcctttgc ataatcctgc aaacttaatg
    13021 gggatcaaag cgtttaaaaa gattttacct gacattttga gtgtggctgt attcgataca
    13081 tctttccact caacaatgcc aaagcaaaat tatttatata gcttaccggt gtcttattat
    13141 gaagatttca aagtaagaaa atatggcttc catggcacaa gtcatcgtta tgtgtcggaa
    13201 cgtgcggcaa aattattgaa caaaccgatc gaagaactaa aaatcatcac ttgccactta
    13261 ggaaatggtg tatcgatcac agcagtcgat ggaggtaaat ccatggatac ttctatggga
    13321 ttcacaccat tagctggggt gacaatgggt acacgttcag gtgatatcga tccagctgtt
    13381 ctcccatatt taatggaaaa attagagatt gatattgatg aaatgatcaa tgttttgaac
    13441 aagaaatctg gtctgctagg cctaacagga ttgtctagtg atatgcgtga tcttgaaaag
    13501 aactatgaaa aagaacatat tcgtttagct tatgacattt tcgtggaccg catccgaaaa
    13561 tacatcggcg gttatgtgac aacgatgaat ggtgttgatg caattgtctt tactgctggt
    13621 atcggcgaga atgacggaca tgtacgtagt gaaatcatca aaggtatgtc ttggtttggt
    13681 tgtgaaatcg atccagcgtt gaatgaattg cgtggtgaag aagtagatat ctctacaaaa
    13741 gaatcaaaag taagagtatt agtgatccca acagatgagg aactaatgat tgcccgtgat
    13801 gtggagcgtc tgcgcggcta agccaaagca ttcgttagga taaaagatga aacgcatgca
    13861 agagggaatt cttgcatgtg ttttttttgc ggagaagacc gcaaaatggt aatttaactt
    13921 caatttccct tcttttttac aggatcttct tagggaattt tgcttggaaa agtggtcaaa
    13981 agggaaaaga ctggcatttt atttattgat tttcaggaaa atcccaatat tttattttca
    14041 ttcatcttta taagggacat tacatatgta aaaagaaaaa acatttttag atcagcctcg
    14101 tgggctgtcg actttattct tcgctttatg tttagctaga aaaccgatcc gaaacattca
    14161 ttgatcgaat aataaaaact tgattttcca cctgtacttt gcctgaatcg tgaaagcaca
    14221 ggtatgaaaa tcaagttttt tgttgcgaaa aaacgtccta gtcaatcagt tggccgagcg
    14281 gctggcggct gatctgctcc tgatcaataa cgagtgcttc ttggaagtgt tgctgcaaaa
    14341 agtagcggtc atggctgact gctaggagcg ttccttgata gtcttgcagc atttcttcaa
    14401 tttcttctcg agcatagctg tcgaggtgat tggttggttc atccaaaatc aggacgttga
    14461 ttttttctaa aaagagtttc agcaacgcca aacggatttt ttcaccaccg gataaatctt
    14521 tgatccgttt acccacatcg ctttgataaa agccactttt ggctaattgc cgtcgagcga
    14581 cttcttcgtt tccagtcaat gtgatggcgt aagccagcaa acggctatcg ggatcggcaa
    14641 actgcagctg ctgcggcaaa taaccgattt gcaagctact acctaatttg atggtgccac
    14701 cgtaaggctt ttcctcaccg agtaataatt tgagtaaggt tgattttcct gcaccattgt
    14761 cgccgatgat ggctaaatga tctccacgat agactgcaaa actgctgtct ttgaatagta
    14821 cttgatcagc gtactgctgg tgcaagtttt gaatgatgaa aacttctttg ccagattttc
    14881 caccattaga caagctttgc agccgatttt tcgggggagg tggcggtttg acgagtgtca
    14941 gtttcgccag gcggcgttcc agttctttgg cttttttgaa gaaggactca ttgtctcctt
    15001 catgtgccca ctgacgaaaa cgacgaatca tgactttcaa ccgctggact tctttttgct
    15061 gcagttcgta attttttgtc agctcagcca agcgagcttc tttcaagact cgaaaacggc
    15121 tgtagtttcc gggatactca atcaatgcac cttcttccag ttcccatgtt tttgtggtga
    15181 cttgatcgag aaattgccga tcatgagaaa cgaccagaac cgattttttt gtattctgta
    15241 aatagttttc caaccagcga atactgttaa gatctaaatg attggtcggt tcatcgagta
    15301 aaagtaaatc ggcatcggct gctaaaattt tggctaaagc gactttaact cgttcgcctc
    15361 cgctaagttc tgttaaccgt gcttcctgac ggtgtggaat ccctaagcct tgcaagatcg
    15421 ctgcaatccg gtcttctaat acgtaaccgc ctagttcttc aaagcgatgc tgcagctcac
    15481 cgtaacgggc cagacacttc tctaagtttg tatctggttc tgtcatcaat gcttcgtagc
    15541 gactcatttg ctgtttgagg tcctgtatct cagcggcaga atggagcaag tagtggttga
    15601 cggtcgcttc ggaaactgta agttcttgtt cgaccgtccc gatctttaag ccttttttgc
    15661 gactgataac accgctgtcg acaccttctc tgccggtcaa gatttgtaaa aaggttgatt
    15721 tgccagttcc gttgataccg actaaggcaa ttttttcacc agcttcaatt tgacaggata
    15781 aatcctcaaa taatggattc ccgccgattg tttttttaat agaaattgct tgtatgatca
    15841 tgatctctct ccttgagacc actcaaaaag gccatggtta tccatggcct gtgttattta
    15901 aactcagatt atcatgagaa aaataccttg agatggccat tgattttacg tgaattcaac
    15961 tgttttggac aaacttgtcc cgtcaacagc aactgtaaaa ccaattgcat ggctaaatgc
    16021 gatatggtat cgttggtaat tttcattact tgttatttta gtcatgcgca tcatagtatt
    16081 ttccctcctt cgtgtagttg tcttttccag tgtacctgaa agtgtcagaa agttcaacta
    16141 gcgctgacat ttacttaata tttatcgatg tgtaattctg tcagagagct ttttttatct
    16201 gactgagggt aatgtctcgt ggaccacatc attgtattct gagctaaacc agcgttcagg
    16261 cgaaatcata tggtgtttga taaaaaactt tgtctacatg acttcctttt gccatttgct
    16321 taataccgtt gcattaaaca gctcttctct ttggaaatct caccaacatc gcgttcagga
    16381 gtatcgttgt ggttgcaatg gcaagcggta gcctttcatc aattcttgaa tgatttaccg
    16441 aatgtagcac ttgccttctc gcggtacccg aacccgaaat aaaattttag tttggcgata
    16501 aaatcggtat ccgccatcga tacttcatat tttttcgtat cagattcatc ggaaacttcc
    16561 acattgacga accaataagc tttggcatgc ttaggtcgtt ttaaaccaca ccagggcgac
    16621 taatcgccct ggtgttcact tttttttatt ttacttgaac tcattgactg ttttcccttt
    16681 attttaaaca ttataaagac cgatgagtgc ttgccgcgtc ttttgttttt atcacggttt
    16741 tttgtgcaaa aaaacctgcc gatagttggc aggtcgtcta cgtgttaagc tttggtgtgg
    16801 tctttagctg gcaattggtt ttctaaatca gttcggacaa caagcacatc gcaagctgcg
    16861 tttctaataa catattcaga aacagaacca ataaataaac gttctacagc attcaatcct
    16921 gtggctccta acataatcaa atctacttga ttatcttctg ggatttctct ggcaataatt
    16981 tgttttggtg agccatattc tacgacagag gttacattat tcaagccagc tttcttcgca
    17041 ttgctttcat aatctgccaa tgtttgcttt gccatttcag tagcttgttc tgcaagcatt
    17101 ccatcaaagg atgaaacggt ttggaaagaa cgtgtgtcaa tgacatgtgc taatagaagt
    17161 tctccgttat ttcggatagc tacattgacc gcctttttaa aagctaattc agcttcatca
    17221 gaaccatcta cggcaaccat gatttttttg tattgttgta acataagcat tcactcctca
    17281 agtcaatcgt attgtactct tttattgtag aacactttag ggaaaaagag aattatttac
    17341 tgctttggtt cagcaatttt ttttgcaaat cggatactga aggtggcaga aacaataatt
    17401 acgatcagta aaaagaccaa ggcaataaag cgttgattga aaaaagctgt taaaataccc
    17461 attacgccta aaacagcata tgcagctccg taaaattgta ggaatccttg atttttatca
    17521 tttttgttga tcaatacaaa aaagatatcc tgtttattaa ataaataata gctaacgaat
    17581 aataatacta aagtggcgat aatcattaaa atcctaatca tgaacaaatc ctccaaaata
    17641 agcaacaaat agaaaaagca atttgccaag agcaaattgc tttattcttt aaaagatggt
    17701 aatctccgtt aatgccgttg tttgtcctgt agtattgatc ccgcgaattc aagcaggtgg
    17761 gtcccatggt cgtagcttcg aactaccaaa tgataaggca tgttaccagc agtgacacaa
    17821 gacgggtccc aagatatcaa taaaaatgtt cggtcaacac acaaagagga caattcgaac
    17881 atcacagatt tcccacctct atagtagcat atgaatttaa aaagagcaat gagagagctc
    17941 gcagaaacag aaccgttttc ttgtctagtt ttttggagga tgctttttcc actcttttat
    18001 acggtaatac tgttgaccca gagcctgttc atatttccct gtatcttttg gctgataata
    18061 ctgagcattc ttcagtttat ctggtaaata ttgctgattg acccaagcct gatcaaaatg
    18121 atgaggatac tgataaccca cgccacggtt gagtgatttc gcacctttgt aatggctatc
    18181 tctcaaatga tcaggaacat ctccagcttt gccctctcga atatcagcaa gtgctgcatc
    18241 taatgccatg taggcagaat tggattttgg cgacaagcaa agatcgacga cgacgtctgc
    18301 tagtgggata cgtgcctcag gcaatcccaa tttttcagca gctaatacag cgttcactgt
    18361 acgagccgca gcagcaggat tacctaaacc tatatcttca taaccgataa ccatcagacg
    18421 ccggcaaata cttgccagat cacctgcctc aactaaacgg gcgagataat gaagtgcagc
    18481 atccacatca cttccacgaa tcgatttttg aaaagccgaa ataacgtcat aatgagcatc
    18541 tccatttttg tcatgggtaa gagcttttct ttggacacat tcttcaatga tcgacagtgt
    18601 aagatgaatc cttccttctt tatctgaagg agtcgatagt gtagccagtt ccagcccatt
    18661 caatgcactc cgcaaatcgc cgttcgttgc acgcgaaagg tgaagaagag catcttcgtc
    18721 taactggatt gcttgttgtc caaggccgcg ttctttatcc cttaaagcat gttcgactgc
    18781 caactggatg tcttgttctg ttaatggttt gacttcaaag atctgtgtac ggctgcggat
    18841 cgctggattg atggtaatat aaggattctc agtagtcgct ccgatcaaga tgattcggcc
    18901 actttctaaa tgaggaagca gaaaatcctg ttttgtttta tctaatcggt gtacttcatc
    18961 caataagagg atcactgtac cactcatttt tgcttcttcc gctacaactt gtagatcctt
    19021 ttttgaatct gtagcggcgt ttagcatgcg aaatgcataa ttagtagagc cggcgatcgc
    19081 acttgcgata ctcgtttttc cagtaccagg aggtccatat agaatcatgg aagagagcat
    19141 gcgagcatcg accatgcggc gtatgatttt tccttccccg actagatgct gctgaccaac
    19201 gacttcatcg atcgttcgag gtctcatgcg ataagccaat ggctgttgca taggattttc
    19261 ctccttcttg tttttacgtc ccttaattat atcatattta gcaagatgcc tagaaagaac
    19321 agccttctgt tgttttgttt tcatagctta tccaactaat attgtgtatg ataaagtagg
    19381 tgagaaaaat gacggataaa caaaagatag atgaattttt ttggaataaa acgacgccag
    19441 aagtggcacg ggatttattg gggatgtatt tggagcatga cacaccagaa ggaagattag
    19501 ctggatatat tgtagacgcg gaagcatacc taggtccaga agacgaggcc gcccatagct
    19561 atggtttaag aagaacaccg cgtgtgcggg caatgtatga aaaaccaggt acgatctacc
    19621 tttacacgat gcatactcat cggattttga acatcattac tcagccagaa gggattcctc
    19681 aaggagtaat gatacgtgca atcgaacccg ccgcaatgat tgatcaaatg agtaaaaatc
    19741 gtggcggaaa aactggtcca gatatcagca acggtccggg aaaattagtg gaagcattag
    19801 caattcctca agaactttat ggtcagtcta tagcagatag ttcgttacgc ttagtttttg
    19861 agaaaaaaaa gacaccaaaa aagatcaatg ctttgcctag aatcggtatc ccaaacaaag
    19921 gtgtatggac agaaaagccg ttgcgttttg ttgtgtcggg aaatccttat atctctttac
    19981 aaagaaaaaa ccaaatcgag aaagattggg gttggaggaa agaaaatgaa aaagaaggat
    20041 ctattaacat atttagatga aataattgaa aaacaagtga cagactatga tgtagcttta
    20101 gattgggata caaaaaatca tacgatcgag atcgttgttc gcttgtttgc agaaaataaa
    20161 gcacaatttg agattgatga tgcagaaggg atcgtttcgc aagaaccaat tatcgaattt
    20221 gaagacggcg tacttctttt taatcctcag aaatctgttt ttgatgaacg caattatcta
    20281 gcagtaatcc cttatgaagg aaaaaaaggg ttggcaaaat cagtagctga ttctttagtg
    20341 gaatatctaa atgaagtatt agctcaaggg caaagcgatt tgcttgattt tttggatgaa
    20401 gacgatgacg aagctgtatt cgagcttcac tgggataatc agcaactagc agaattagta
    20461 gaagtaaaac agcaaaatga agcagatact tatttaccgt acccaagtta ttaaggagtg
    20521 acagatatga aatggaatga agtaaaagta gaaactgaaa gtgaagcagt cgaagcagtt
    20581 gctaatattt tgatggaggc aggggcgagt ggtgtcgcga ttgaagattc tttagatgtt
    20641 gaacattttc agtcggatca atatggtgag attttagata aaaatgattt tacatcgctg
    20701 aaagaaggcg cactagtcat ggcttatttt ccggaaacga ctttcttacc ggaaatcttg
    20761 ccttttatca aagatcgtat cacacaatta cctgagtttg gtctagctat tggaaaaaat
    20821 aaagtaacag ttagtgaagt agaggaaagc aactgggcaa cagcctggaa gaaatactat
    20881 catccggtgc gtattacgcg aatgctgacg gttgcgccaa gctgggaaaa ctaccagaca
    20941 gaagatcctc tagaaaaaat tatcacacta gatcctggta tggcatttgg cacaggcact
    21001 catcccacga cttccttgac attgacagca ctagaaacag tcttgcgtgg tggtgaaaca
    21061 ttgctagatg tgggaactgg gtcgggcgtg ctaagtattg cagcaaaata tcttggtgca
    21121 aaagatgtct atgcctttga tttagacgaa gtagccgttc gttcggcgaa agaaaatatg
    21181 gatatgaatg aaatagccaa agatgtccat gtatcagcta acgatctttt gacaggaatc
    21241 gagattgaaa gtgatgtaat cgttgcgaac attttagcag atatcatctt attgatgatc
    21301 ccagatgctt ggcgtttact gaagcaaaca ggcacgctga tcgtttcagg aatcattgaa
    21361 gagaagaagc aaatggttct ggatgccatg ttagaacaag ggtttatcgt ggatcaaatt
    21421 ttccagcaaa aagactggta tgcaattatt ttgaaaaaac cagaggtgga atagatgcag
    21481 cggtattttt taaaagaatc atatgaatca aaagactatt ttgttttaga aggggaaaac
    21541 tatcaccaca ttgtacgggt tatgaggatg gaacccgagg atgaagtttt tttggcattc
    21601 aatgatcaaa tagccattgt tgcagaaatc acggagatta ctgaagaggc tgtttatctg
    21661 aaagaaatta aaaaagaaga aaatcaaaag gaactgccaa gttcgattac catagcgagt
    21721 ggctatccta aaggggaaaa gctggattgg atcgttcaga aatccactga attaggagcg
    21781 caagcttttc ttggtttccc ggcatcagcc tctgtcgtta aatgggatgc aaaaaaacgt
    21841 atgaaacgac aacaacggct tgaaaagatt gctcaagagg cagcggaaca atcccatcgg
    21901 cagatcgtgc catcagtaga gttattggaa acgaaacaag atttatttga gcggctagat
    21961 gattatgacg tggtcttggt tgcttatgag gaatcagcaa agcaaggcga aaaatcaaat
    22021 gcagccaaaa ttcttagtga aacaaaacca gatagtcgaa tcttagctgt ctttggacca
    22081 gaaggtggat tatcccgcga tgaagtcgat tattttgtag aacacaaagg gatactttgt
    22141 ggattaggac caagaatcct tcgtacagaa acagcacctc tttatttatt aagtgctgct
    22201 agctatcaat gggaattaat gaatccttct ttcagctaac gttcttcatt aataaaagag
    22261 tatcgacaga aagaattgaa aaaatagtca acaatttgta taatagaaac aattatttat
    22321 acaatggata cgaaaaatcg tttgaaaaag cttttaaaaa gcgaacattt ccgtaaaaaa
    22381 acgtataact gcacggattt tgggacaatt atcaaacaga tatttgtccc gattcccgtt
    22441 ttaccgaaaa aagaaagggg gatcgattcc tgtgacaaaa gaagaaattt taacgggacc
    22501 cggtgtcata aagctcgtta gtcaatacat gggtcccgaa catgtagcat ttgttgagaa
    22561 agcatgcgaa tacgcgactg ctgcacatga cggacagttt agaaaatcag gcgaacccta
    22621 cattattcat cctatccaag tcgcaggtat attagcagat ttaaaaatgg atccccatac
    22681 agtggctaca ggcttcttac atgatgttgt tgaagataca gaaatcactt tagaagatct
    22741 gagagaagaa tttggcgatg acgttgctat gttagtggac ggcgtaacca aattagggaa
    22801 aataaaatat aaatcccacg aagagcagct agcagaaaac caccgaaaga tgctgctagc
    22861 aatggctcaa gatttacgag ttatcatggt caaattagct gatagactac ataacatgcg
    22921 tacgttgaag cacctgcgag aagataagca aagaaggatc gctcaggaaa ctttagaaat
    22981 ctatgcgcct cttgcacatc gtctagggat cagccggatc aaatgggaat tagaagatac
    23041 agcacttcgt tatctaaatc caaaacagta ttaccgtatc gtccacttga tgcagacgaa
    23101 gagagaagaa cgtgaaaaat acgtaagtgg tactgttgaa gatattcgaa tagcgacaga
    23161 agagctgggg atttttgcag aaatctatgg acggccaaaa cacatttatt caatctatcg
    23221 taaaatgaaa gatcagaaaa agcagttcaa cgaaatttat gacttgctag ctattcgagt
    23281 gatcgtagat tcaatcaagg attgttatgc tgtattagga gcaatccaca caaaatggaa
    23341 accaatgccc ggcagattta aggattatat tgccatgcca aaagctaata tgtaccaatc
    23401 tttgcatact accgtgatcg gtccggcagg aaatccggta gaaattcaaa tccgaacaca
    23461 ggaaatgcat gaaatcgctg aattcggggt tgctgcacac tgggcctata aagaaggaaa
    23521 aaatgaaaaa gtagaaccag atggtatgac gaaacaatta agctggttcc atgagatact
    23581 cgaacttcaa gacgaaagct atgatgcttc tgaatttatg gaaggcgtaa aaggagatat
    23641 ctttagtgat aaagtctacg tcttcacacc aaaaggagac gttactgagt taccaaaagg
    23701 atccggacca ttggactttg catacagtat ccatacagat atcggtaaca aaaccactgg
    23761 tgcaaaagta aatggcaaaa tggtgcagct tgattacaaa ttgaaaaacg gagatatcat
    23821 tgagatcatg acttctccaa attcatttgg cccaagtcgc gactggttga aattagttgc
    23881 tactagcaaa gcaagaaata agatcaaacg tttcttcaaa gcccaagatc gagaagaaaa
    23941 tgtgatcaaa ggccacgaat ccgtggtcaa atgtattaca gatctaggat ttacgcctaa
    24001 agatattttg acgaagaaca aactgcaaga agcactcgat cgttttaatt atcaaacaga
    24061 agatgatctc tatgcagctg tagggtatgg agaagttagc cccttgacga tggccaatcg
    24121 tctgactgaa aaagaacgta aagaacaaaa aatcgagcag caaaagcaag aagcagaaga
    24181 aatcatgaat cagccgaaaa aagaacctga caaaatgaaa gtacgtcatg aaggtggcgt
    24241 tgtcattcaa ggggtagaaa acttactaat tcgtatcagt cgctgctgta atccgattcc
    24301 tggtgatgat atcgttggtt atatcactaa aggcagaggg atatccattc atcgtcgaga
    24361 ttgtccgaat gttcagcctg acaaaccaaa tgtagcagaa cgtttgattg aagtcgaatg
    24421 ggaagataca tcgaatacac gaaaagagta tgatgcagat ttggaaattt acggctataa
    24481 tcgttcaggc ttattgaatg atgtacttca aacagtcaat gcgctaacga aaaatctcaa
    24541 cagcgttgaa gcacggacga ataaagataa aatggcgacg atccatttga cggttggtat
    24601 ccagaattta tcccacctaa agagtatcgt ggataaaatc aaagcagtac ctgatgtcta
    24661 cagtgtacgc cggacgaatg gataggagga cagatatgag agcagttgtt caacgggtaa
    24721 gtaaagctgc tgtgtcagtc gatcagcaag aaattggaaa aattggctac ggcctacttg
    24781 ttttattagg cattcatgaa accgatacgc aaaaagatgt ggactatctg gtaaaaaaaa
    24841 ttgcacaaat gcgtattttt gaagatgaac aaggaaaaat gaatattagt gtagaagatg
    24901 tgggaggaca aattttaagt atctctcaat tcacactgtt tgcggatacg aaaaaaggaa
    24961 atcgaccaag ctttgtggaa gccgcacgac cagaaacagc tattccttta tacgaatcat
    25021 tcaatgaagg aatcagaagt cgcggcatca cagtcgctac cggacaattc ggagcagata
    25081 tgtcggtttc tctcgtcaat gatggacctg taacgatcat tattgattct aaaaacaaat
    25141 aaagtaatct ggttttcact agtaaaaact atgaaacacg tcgcttaagt tagactgata
    25201 aactctaact taagtggctt ttttgtctgc aaaaagcgct tcttttgtca gcagtcggaa
    25261 aaaaagttaa gcttaaatta tacaagttat tttttatagg aggttgctga agatgaaaga
    25321 agtaccagta gtagatatca aaatcacaga tttaaaaaaa ttgtatcaaa aaggatacaa
    25381 catgttggag gagttacgcc atgaagcgga cgctcccgtc gtcaaagcaa agattttcaa
    25441 taaagaagct atcacgatct acggatcatc agcagcaaaa gtattttatg atccaaggaa
    25501 tttcaaacga aaaggtgcta tgccaaaatt agtattgaag acactttttg gtcaaggtgg
    25561 agtacagact ttggatggag ctgctcatca ccatcggaaa aatattttta tggatctaat
    25621 gacaccggaa agaatggaag attatcatcg tatcttagat aagaatctga cacaagcact
    25681 tgaagcacag catggtcaat ttgaactatt tgatttaagt aagatggttt tctttacatc
    25741 tatttgcgag tgggcaggta tcaatttatc agcgatttct aaagatgagg tcgaaaaatt
    25801 agcagaatat caaatctcta tgatcagcgg aacgtttact tctccgattg atcacataaa
    25861 aggtgtcgaa aatcgcaaaa aatcagaaaa atgggcgcaa ggcttgattg aagaagctcg
    25921 acaaaatcct gtggctggaa aagaaaatgt ggcattatat gcttttgcca atgccacaga
    25981 tttagatggt cagcttttac ctctggaagt ggcagctgtt gaattattga acatcatccg
    26041 tccaacggtt gctctaactg tgtgggcggc attgatggga catgcacttt tcagtagacc
    26101 agatttgtat cagcaattaa aaaatgactt ttcgacgtta caagatccgt ttattcaaga
    26161 aatgagacgc tattatcctt tcttcccaat gctacctgcg atttcgctga aagaagtaga
    26221 agtagatggt tatcgtatac cagaaggcag ttgggttatt ttagatttat atggaacaga
    26281 ccatgatgaa cgaacagttg aagcgccaga ttcctttatg atcaaacggt atgtagggaa
    26341 agcaaaagat atttcctata aagaagaata tgagatgatt gcacaaggcg ggggaaattt
    26401 tcgacaaatg catcgctgtg caggagaatg gatcactctt catagtctac gtgtgttttc
    26461 cgatcagcta gtaaataagt ttgagttctc tgtacctgaa caagattgga cgattccatt
    26521 caatcagttt ccgacttatc cgaatagccg agcgctactt tacaagaatt agattagcat
    26581 aaacttatcg aaaaaaagga agatcaaaca gtgctgatct tccttttttc atattactat
    26641 aaattgataa ggtcaattga tcaaaatcca cgaaatgctt catcaatggt ttgataatct
    26701 tcattggata aatgcaaatc taaagcttgg acattgtcag atacttgctc tggacgctta
    26761 gctccaggta taactacaga cactcgtgga ttcttcatgt accaagctaa aacaagttgc
    26821 gcaggagtgg cttggtatct tttagcaatg gggcgaagta catcgacagc ggttaaaatt
    26881 tctctgaaac gttctccttg gaaatctgga tttctttttc gaggatctcc ttcaccaaat
    26941 tgtttttcct caccaagttc atattttcct gtcagcaaac cggaagcaag aggaaaatag
    27001 ggaacaaaac tgattttgtt tttttcaaga taagggaata attctttttc agcctgccga
    27061 tggatcaaac tgtatttatc ttctactaca tcgacatatc catctgcatt cgcttctttc
    27121 aattgttcta acgtgaagtt tgacacaccg actgctcgga tttttcctgc ttcttttaat
    27181 tcgtgcaatg tagcaactga ttcatttttt ggtgtgcttt catccggaaa gtggatataa
    27241 aaaatgtcga tgtaatcagt ttgcagacgt tttagtgcat cttccaccga ttgtttgaga
    27301 aactcaggag aattatcaaa tgttcgccct ttatttggta catgagcagc ttttgtagcg
    27361 atgacgacac gtgagcgatc atattctttt tccttcagta cctcgccaat cagttcttcg
    27421 gaacggccgt ttccgtaagc ataagcggta tcgatcaaat tgatcccgct attcaaagct
    27481 gtacgaacta cttgttttcc tgtctcatct tccaaaccgt caaaaagatt atgtcctcca
    27541 acggcatttg ctcctaatcc aagctgttct gcgtagactt gtgaatgtcc gattcttatt
    27601 tctgccatag ctgattcctc ctttttgtct agtctaaaac aaaataccaa aaagctgaac
    27661 taaaacgttt ttgtgagggg aaatagtcag atatctcttg actttgagac tggtttttag
    27721 taggttataa gtaatatcga atgtcaatga aagagcgagt aagtttttga aactttacaa
    27781 gagaggatca tcgaggctga aaatgatcta aagtttcatt agcctaaaga cactctggag
    27841 atggacgagt gaaaagccgt cccgcgtacg agcgttattc gtaagaggaa agagaaatct
    27901 ttcaaaatta ggtggtaccg tgtatgaatt tcattcaccc ttgttcatga tgaacaaggg
    27961 tgattttttt atttacatag ctaagaaagg gagagaaaac tatgagtttc caaagaccaa
    28021 aaggaacaaa tgatattttg ccaggcgaat cagaaaaatg gcagtttgtc gaagaaacag
    28081 cacgtttatt attcagagat tatcagtata atgaaatgcg tacaccgatt tttgaacact
    28141 atgaagtgat atcccgaagt gtaggggata caacggatat cgtttcaaaa gagatgtatg
    28201 atttttatga caaaggggaa cgccatgtga cgcttcgacc agaaggtaca gcaccaatcg
    28261 ttcgttcttt tgttgagcat aaattgttcg gcccagagta tgcgaaaccg ttcaaaactt
    28321 tttatatggg accaatgttt cgctacgaac gccctcaaaa aggacggtta cgtcaattcc
    28381 atcaaatcgg agtagaagca tttggatcag aaaaccctgc aactgatgtg gagagcatgg
    28441 tgatggcact tgatttcttc aaacagttgg ggatcacgca aatccggcta gtcatcaatt
    28501 cattaggtga taaagaaacg cgtcaagcct atcgtcaagc attgatcgac tatcttttac
    28561 cttttgaatc agagctgagt gaagactcta aacgccgcct tcatgaaaat ccattacgcg
    28621 tattggacag taaagacaaa cgagatcaaa aatttgtggc agaagctcca tctatcttag
    28681 attatctaag cgagcctgct caaaaacatt ttgataccgt tgtttccatg ctggatgcat
    28741 tggctgttcc ttatgaaatc gacagtaata tggttcgcgg actagattat tacacacata
    28801 cgatttttga aatcatgagt gacgcaccaa aaatgggggc acaagcaacg atttgcgcag
    28861 gcggacgtta tgacaatcta gtggaagaac taggtggtcc ttcaacacct ggcttcggat
    28921 ttgcaatggg tatcgagcga ttactcttga ctatggaggc agaggaagta gttatccctg
    28981 catttaatga gttggatgct tacgtggtcg cactcggaga cgaaacaaat atcgaagcat
    29041 tgaaagtggt ccaagcgatt cgaaactttg gtttttcagc tgaccgcgac ttcatgaacc
    29101 gtaaagcaaa agcgcaattt aagacagcag ataaagcgaa tgccaaatta gtattggtga
    29161 tcggtgaaga tgagcttgct agtcaaacga ttaatgtcaa agcaatggca agccgaaaag
    29221 aaaaaagttt tccattagaa gagatatatg aacattttga tgaagtctat gatgaaatga
    29281 ctttattcga gtaggaggaa aaaaataaat ggcacaaaga acgatctatt gcggattagt
    29341 ttccgaacaa caattagaac aaacagttac attaaaagga tgggtacaaa aaagacgaga
    29401 ccttggggga gtaatcttta tcgacctacg tgatcgtgaa ggaatcgttc aaatcgtctt
    29461 taatcctgaa atcaacaaag aagcatggga aatcgcggat aaatgtcgca gtgaatacgt
    29521 gatcgaagtg actggggaag ttagaagacg cggagaaaat gcagtaaatc ctaaaatggc
    29581 cactggtgaa ttcgaagtga ttgcaagtga aatcgtgatt ttgaatcaag caaaaacccc
    29641 gccatttcaa attgaagatg atcaagcaat cagtgacgaa atacgtttga aatatcgtta
    29701 tttggatctg cgtcgtccaa aaatgactaa aaacatcaaa ttaagaaatg cgacaacaaa
    29761 agcgattcgt cattatttag atgataatga ctttctcgat atcgaaacac cttacctagg
    29821 gaaatctaca ccagaaggcg caagagacta cctagttcct tcacgtgtcc atgctggaca
    29881 tttctatgcg ttgccgcaat ctcctcaatt gtttaaacaa ttgctgatga atgctggatt
    29941 cgaccgttat tatcaaatcg ttcgttgttt ccgcgatgaa gatttacgtg gagaccgtca
    30001 gcctgaattt acgcaagtag atattgaaac aacgttctta acagcagaag aaatccaaac
    30061 ttacacagag ggattgattg cgaaggtaat gaaagaagtt cgcggtatcg aagtcacatt
    30121 gccatttcct cgtatgacct atgatgaagc aatggctcgc tacggcagcg acaaaccgga
    30181 tacacgtttt gatatggaat tgatcgatct aagcgataca gtcaaagaag tagaattcaa
    30241 agtcttccaa atggctcttg aaaacggcgg tgtcgtgaaa gcattgaatg ctaaaggcgc
    30301 tgcagatcgc tactcacgaa aagacatgga tcagttaggt caatatgtag gacaattcgg
    30361 agctaagggg cttgcatggc tgaaagtaga agaagacgga ttgaaaggtc caattgctaa
    30421 attcatggga gaagcaacag aagcaatcat taaagcaaca gatgcaaaac caggtgactt
    30481 gctgatgttt ggcgcagata aaagtgaaat cgtcgctgct gcattaggtg ctatccggac
    30541 acgtttagga aaagaattag gactaattga tgaatcgaaa ttcaatttct tatgggtaac
    30601 tgattggcca caatttgaat tttcagaaga agaaggtcga tatgtctctg ctcaccatcc
    30661 attcacgatg ccaaaagaag aagatatccc gttattggct gaagaccctg caaaagtcta
    30721 tgcagaagct tatgatatcg tcttgaacgg ttatgaacta ggcggaggtt ctatccgtat
    30781 tcatactcgt gagcttcaag aaaaagtact agaaactcta ggctttacaa aagaacaaat
    30841 ggaagaacaa tttggtttct tgttaacagc tttagattac ggattccctc cacatggcgg
    30901 tattgcatta ggattggacc gttttgcaat gttattagcc ggagaagata atattcgtga
    30961 agtcattgcc tttcctaaaa acggaaaagc agcagatgtg atgagtgatg caccaagtat
    31021 ggtttcgcct ttacaattgt tcgaattgaa tattgatgta acgaatatag aagaatagcc
    31081 gataaaaagg taaaaaggat ttgtcgaata cgcttctttt gacaaccttg atttaattga
    31141 aaaacacttt ataatgaagc cataacatat aaagcggggc ttttccatga aaaaaacatt
    31201 cgaaaattgg gcttatcatg attacacgac caagctttcg gtatctatcg tttatgcgtt
    31261 gatcgcatca gtcgcattga atttctttta tcagccagga catatttatt caagtggtat
    31321 tactggtcta gctcagattt tgacgacttt gtcaaaatca ctgataggat tcgaagtacc
    31381 ggtatcaaca actttgtatt tactgaatat acctttgttt gtattggcgt ggttaaaaat
    31441 cgggaagaag tttacaattt tcacttttat cacagtcact ttgacctccc tttgtatcca
    31501 tattttaccg gaaacagtcc tatctaccga tccaatcatc tgtgcgttgt ttgggggggc
    31561 tgtgatggga ctaggtattg ggctagcgtt gagaaacggc ctatcatcgg gcggtctaga
    31621 tatcgtgagt atcacgattc gtaaaaaaac aggaaagtcg attggttcta tttcgatcta
    31681 cttcaatgca ttgatcgttt ttgttgccgg aattctattt ggctggcaat atatgtttta
    31741 cagtacgttg tctattttcg tcagtggaaa agtaactgat gtcgtttata ctaaacaaaa
    31801 gaagatgcag gtaatgatcg taacgaaaca tccagaaaaa gtagtaaatg aaatccaaaa
    31861 ctgtatgcgt agagggatca cgatcatcaa tgaagcagaa ggtgcttata agcatgataa
    31921 gcagacagta ttgatgacga tcgttacacg atacgaactg cctctactta gagaagcaat
    31981 gaaagcttct gatccacaag cttttgtaag tattgcagaa aacgtccaga tacttggtcg
    32041 tttctatgag gatggcattt agatcgagtt tgacaaaaat tcatgaaata ctgctgtaga
    32101 cagacgttcg tttgtctgca gtttttttct accatagtag aatcagcaaa gaaaaactgc
    32161 ttttttattt gaaattttct taaagttgaa aaaaagcatg tttatttttt taaatttatg
    32221 ggatgataga aaaaaatagt agagaaagga cacgattcta cttgctattt tcacttaata
    32281 cccgtatatt acgaatgaaa aaagtttatg aaaagttgga atattgaatg gaaaaacaaa
    32341 aaaggttaaa aaacagccgc tacatcactg ggtttgatgg gctccgttca ttagctgtgg
    32401 tgggtgttat cttctatcac cttctgccaa ctagtatgaa aggcggctat ttgggcgttc
    32461 cgattttttt cgtcgtatct ggttatttga tcacggatct gctgcggcag gaatgggaac
    32521 aaaatggaaa aatcaatatt tggcaatttt atgtcagaag aatgaagaga ctctatccgg
    32581 cacttgtttt tatgcttgtg acagcttcgg cttatatcac tttgtttcag cgagggctgt
    32641 taaacaatct tcgaggagtt gtggtcagca gcttactgta tgtcaacaac tggtggcaaa
    32701 tcaataacgg tttatcttat ttcgatcgat ttgctaatga gtcaccgttt acgcatatct
    32761 ggtctttagc agtagaaggt caaaactatt tggtttggcc gatcttgttt gtattgttga
    32821 tggtatttgt tcgtaaaaga aaatggatct tttatactgt gttaggtaca tccttcctct
    32881 ccgccatctt gatgatgatc ttgtatacac caggaggcga tccaacccgt gtttattacg
    32941 gtaccgacac tcgtctgttt tctatatggt tgggaagtgc gcttgcgttt gtttggccaa
    33001 gtacgcgttt aaagaaaaac atcccgaaac aagcgaaaaa tattctgaat atcgctggag
    33061 gaatctcgct tttggcactg attctttgct tcttcttttt agatgatcat tacaatttca
    33121 tctattacgg aggaatgctc ctagtgagtc tgttatgcgt agtgctagtt gcagtgacag
    33181 cacaccccgg agcaagtttg aatcgatggc tgacaaatcc agtatttact tggattggca
    33241 aacgaagcta tggcatttat ctgtatcagt ttccagttat gattttttat gaagcaaagg
    33301 tgactgatat tgccgatcat gttttgttgc atactttagt ggaaatcaca ttgattctaa
    33361 tcatcagtga actttcttat cgatatgtgg agcgtccgct agcacgtttt gattatggtc
    33421 gtacattcca agtgatgaaa ggatggttca gcaaaccgat catcagtaag agcaaaccat
    33481 gggttgttcc aggcacatta cttgtagcaa ttgcactcgt tggtttcgtt acggcaccga
    33541 aaaacgctgt aacagccgat caaaaacaac tgcaggcaaa aatcgctgaa agtaaaaaat
    33601 tagcagaaga aaccagaaac aattcagaaa acaccactag ttcggttgac caagcgatcc
    33661 ttgataagta cgagttgtcc aaggcacaag ggaataaggc acaaaaatta gaactaacgg
    33721 catttggtga ttcagttatg ttggatgctg caacggatct acaagaactt tatccaaaag
    33781 tagtggtaga tggagatgtc ggacgacaat tatatgccag tgtaccgtac attgaaaaat
    33841 taaaggaaca agatttgttg aaagacactg ttctgatcgg actaggaacg aatggctcat
    33901 tctcggaagc tcagtttgat agtgtgatgg atgcaatcgg tgatcgaaaa gtatactggg
    33961 tcaatgtccg agtaccgacg aagcgctggc aaaatgacgt gaatgcgatg cttgaacaga
    34021 tgacgaaaaa atacgacaat atgacgctga ttgattggta cagctacagt aatgaccata
    34081 gtgactggtt ttatgatgat caagtccatc caaatcctga agggatgaca cattacattc
    34141 acttagtcag cgaagccttg ctaggaggaa gttcaagtac gaacagcagt gagacaaacg
    34201 tgacagaatg atagctacaa aaaacttcag gcaaaaacat ttgtttttgc ctgaagtttt
    34261 tttatattta ccgtgttttt aacattcata tagattcagg aagcaaaacg gttgagtgtg
    34321 tctgtaaata acgttctttt tgttttcggg tgagtttttt gaatgcagct tctgcttttg
    34381 ttgcttcgct tcttgaagaa aatacttctg catggatcat cttaacaggt cttctttttt
    34441 gaagacgagt atatttagca ccagtaccat tgttatgttc ctctaatcgt ctagaaagat
    34501 cggttgtata tccaccataa aatgtctgat ctttacagaa taatacgtaa aaataatgtt
    34561 catttgccat agagcatctc acgaatctct gcagtgtatt ctccatccat attgtaagtg
    34621 atcaatggtg gagcgacttt gaatccgtct aatttgcctt ctttgattcc ttcaactaac
    34681 aaaatatttg cctcttttcc aggttttggg taaacaaatt ggatcctttt aggtgcaatt
    34741 cgatagtctt ccatgacctg aatgatttct aagaaccgat caggacgatg gaccatagta
    34801 aagcgtccat ttgtttttag tagcttactt gaaatatcga tcacttcttc taacgtcgta
    34861 tgaatctcat gacgggcgat tgccaggtgt ttattagggt tcgttttatt tgttggcagc
    34921 cctttgaaat aaggtggatt acagacgact aagtcacaag aattatgtcg aacgacagat
    34981 aagctgtctt tcagatcgat ggtgtggaca gtcatttgtt catttaaatg gttaagcgcg
    35041 atactacgtc ttgccatgtc tgctagacga ggttgaagtt cgatagcgtc gatagccgcc
    35101 tgggttcgtt tacttaaaaa aagtccaact gcgccatttc ctgcacaaag gtcaacaatc
    35161 ttcccttttt taggtacacg ggaaaagtga gcaagcagca cagcatctaa agaaaaagaa
    35221 aacactttgg aactttggat aatcttgata tcttctgcgt ataattggtc gattcgttcg
    35281 tcttcgtgaa gcatggattc cctccaaaat gaaaaaaata gtcgtctgta ttatactatt
    35341 tttattaaaa agaaccaagg tggcttgtca aacctctatt ttttatgcat actatgacca
    35401 taagaaggga aaggaagaga ctatgtttta tcgatttatg cgcggggtag ttcgagtact
    35461 attagcctta gttaatggaa atgcccgcta tgagaataaa gaagttttac cgcaagatga
    35521 gaattacata ctagttgctc cccatcgtac ttggtgggac ccattatatc tggcggtagc
    35581 tgcagcaccc aaggaattca gctttatggc aaaagaagaa ctgttcaaaa atccagttct
    35641 gcgatttata ttaactcgat ccaatgcttt tccagttaaa agagaaaatc caggaccaag
    35701 cgtcattaaa acacctgtaa agattttgaa atcgacaaat ttgagtttga tcatgtttcc
    35761 cagtgggaca agacatgcta cagaacttaa aggcggaatg gcattgattt ccagaatgtc
    35821 taaagcgaaa atcgtgccag ctgtatatca aggtccgttg acacttgggg atctgttcaa
    35881 gcgtcagaga gtgacagtgc gtttcggcga accaatcgac ttatcagata tcaagaaaac
    35941 ggataaagaa ggtatggcgg agatcgaacg acgaacacaa gcagcttttg acaaattgga
    36001 caaagaagtg aaccctgatt tcaaatatga agtcaaaaaa aaataaaatg ataagtttat
    36061 gcgtgggcgg tcttttgaat ctactgtcct gttcagttca gactttttca atgaaaacga
    36121 gggagagacg tcaagtctgc cctctttttg cgttccaata t
//
LOCUS       DBBGSZ010000026        34959 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.026, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000026 DBBGSZ010000000
VERSION     DBBGSZ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.026"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            153..1859
                     /gene="efbA"
                     /locus_tag="ACIZE5_001757"
     CDS             153..1859
                     /gene="efbA"
                     /locus_tag="ACIZE5_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HGC6108884.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2017..2919)
                     /locus_tag="ACIZE5_001758"
     CDS             complement(2017..2919)
                     /locus_tag="ACIZE5_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGC6108885.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2916..3608)
                     /locus_tag="ACIZE5_001759"
     CDS             complement(2916..3608)
                     /locus_tag="ACIZE5_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HGC6108886.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3651..4292)
                     /locus_tag="ACIZE5_001760"
     CDS             complement(3651..4292)
                     /locus_tag="ACIZE5_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbR-like 5'-deoxynucleotidase"
                     /protein_id="HGC6108887.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4330..4644)
                     /locus_tag="ACIZE5_001761"
     CDS             complement(4330..4644)
                     /locus_tag="ACIZE5_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108888.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4632..5261)
                     /gene="pyrE"
                     /locus_tag="ACIZE5_001762"
     CDS             complement(4632..5261)
                     /gene="pyrE"
                     /locus_tag="ACIZE5_001762"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HGC6108889.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            complement(5268..5984)
                     /gene="pyrF"
                     /locus_tag="ACIZE5_001763"
     CDS             complement(5268..5984)
                     /gene="pyrF"
                     /locus_tag="ACIZE5_001763"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HGC6108890.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            complement(5981..6913)
                     /locus_tag="ACIZE5_001764"
     CDS             complement(5981..6913)
                     /locus_tag="ACIZE5_001764"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HGC6108891.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6910..7686)
                     /locus_tag="ACIZE5_001765"
     CDS             complement(6910..7686)
                     /locus_tag="ACIZE5_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HGC6108892.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7740..10925)
                     /gene="carB"
                     /locus_tag="ACIZE5_001766"
     CDS             complement(7740..10925)
                     /gene="carB"
                     /locus_tag="ACIZE5_001766"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HGC6108893.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDLADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10930..12006)
                     /locus_tag="ACIZE5_001767"
     CDS             complement(10930..12006)
                     /locus_tag="ACIZE5_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HGC6108894.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12011..13291)
                     /locus_tag="ACIZE5_001768"
     CDS             complement(12011..13291)
                     /locus_tag="ACIZE5_001768"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HGC6108895.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13310..14236)
                     /locus_tag="ACIZE5_001769"
     CDS             complement(13310..14236)
                     /locus_tag="ACIZE5_001769"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HGC6108896.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14249..15532)
                     /locus_tag="ACIZE5_001770"
     CDS             complement(14249..15532)
                     /locus_tag="ACIZE5_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HGC6108897.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15546..16085)
                     /gene="pyrR"
                     /locus_tag="ACIZE5_001771"
     CDS             complement(15546..16085)
                     /gene="pyrR"
                     /locus_tag="ACIZE5_001771"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HGC6108898.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16320..17231)
                     /locus_tag="ACIZE5_001772"
     CDS             complement(16320..17231)
                     /locus_tag="ACIZE5_001772"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGC6108899.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17228..17692)
                     /gene="lspA"
                     /locus_tag="ACIZE5_001773"
     CDS             complement(17228..17692)
                     /gene="lspA"
                     /locus_tag="ACIZE5_001773"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HGC6108900.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17697..18395)
                     /locus_tag="ACIZE5_001774"
     CDS             complement(17697..18395)
                     /locus_tag="ACIZE5_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HGC6108901.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18382..18768)
                     /locus_tag="ACIZE5_001775"
     CDS             complement(18382..18768)
                     /locus_tag="ACIZE5_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108902.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18915..20585)
                     /locus_tag="ACIZE5_001776"
     CDS             complement(18915..20585)
                     /locus_tag="ACIZE5_001776"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HGC6108903.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20768..21001
                     /locus_tag="ACIZE5_001777"
     CDS             20768..21001
                     /locus_tag="ACIZE5_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HGC6108904.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21100..21531)
                     /locus_tag="ACIZE5_001778"
     CDS             complement(21100..21531)
                     /locus_tag="ACIZE5_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HGC6108905.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21610..22023
                     /locus_tag="ACIZE5_001779"
     CDS             21610..22023
                     /locus_tag="ACIZE5_001779"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HGC6108906.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22061..23209)
                     /locus_tag="ACIZE5_001780"
     CDS             complement(22061..23209)
                     /locus_tag="ACIZE5_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HGC6108907.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23331..23927)
                     /locus_tag="ACIZE5_001781"
     CDS             complement(23331..23927)
                     /locus_tag="ACIZE5_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGC6108908.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24127..26769)
                     /gene="alaS"
                     /locus_tag="ACIZE5_001782"
     CDS             complement(24127..26769)
                     /gene="alaS"
                     /locus_tag="ACIZE5_001782"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HGC6108909.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27157..27588
                     /locus_tag="ACIZE5_001783"
     CDS             27157..27588
                     /locus_tag="ACIZE5_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6108910.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27633..28982)
                     /locus_tag="ACIZE5_001784"
     CDS             complement(27633..28982)
                     /locus_tag="ACIZE5_001784"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGC6108911.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29052..30215)
                     /locus_tag="ACIZE5_001785"
     CDS             complement(29052..30215)
                     /locus_tag="ACIZE5_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGC6108912.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30344..30667
                     /locus_tag="ACIZE5_001786"
     CDS             30344..30667
                     /locus_tag="ACIZE5_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108913.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30850..32199)
                     /locus_tag="ACIZE5_001787"
     CDS             complement(30850..32199)
                     /locus_tag="ACIZE5_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGC6108914.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32268..33221)
                     /locus_tag="ACIZE5_001788"
     CDS             complement(32268..33221)
                     /locus_tag="ACIZE5_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HGC6108915.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33323..34513)
                     /locus_tag="ACIZE5_001789"
     CDS             complement(33323..34513)
                     /locus_tag="ACIZE5_001789"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HGC6108916.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            complement(34713..>34959)
                     /locus_tag="ACIZE5_001790"
     CDS             complement(34713..>34959)
                     /locus_tag="ACIZE5_001790"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108917.1"
                     /translation="IRKNRTVTRLLSQSFFRIQQVKLLRNIQRVKLKIADKRRWKFYV
                     FLLVYAINKLNIQNTIDFNERASINGCVVFICPGRVK"
BASE COUNT         9952 a         7640 c         6119 g        11248 t
ORIGIN      
        1 taaaaatttg gatttcaacg atagaaacac tgttttttat gtaattagtc caagattttt
       61 ctagactttt gctttactat tcggccaaat tggtttttct tctttttttc gttataatga
      121 atatacttat gaaaagaaat gaggaatgaa ccatgtcctt tgatggtgta tttacccacg
      181 cgatggtcaa cgaattgcgt gaaacgttac tatctggccg gatctcgaaa atccatcagc
      241 cttatgaaaa tgaaatcgtg ctggtgattc gttcacgcgg caaaaaccat cgattattat
      301 tatctgcgca cccaagttat gctcgtgtac agattaccca aatcgattat cagaatcctg
      361 ataatccgcc taacttcgtg atgatgcttc gaaaatattt ggatggcgct attttagaag
      421 acatcgaaca aatcgaaaat gatcgagtga tccatttcca ctttgctaaa cgaaacgagt
      481 tgggtgatct acaaaatatc atattgatcg ttgaattaat gggacgtcat agtacgatcg
      541 tcttagttaa tcgagaaact ggaaaaatac tggatgcgat caaacacatt ggaagctctc
      601 aaaacactta tcgttctttg cttcctggtg tagaatatgt tgctccgcca aaacaagagg
      661 tcttgaaccc atttagctcc gagaaagaaa aaatctttca gcggctttcc caaactgaac
      721 tagatccaaa agcaatccaa cgtcagtttc agggaatcgg tttcgatatc gctcaagagc
      781 tgaccaaaag attactggaa cgtcctaatg aaaagatggt tgtatgggac gaatttttct
      841 cagccatcag ccatcagcct attcctactt tttacgaaac ggaaaataaa gattttttca
      901 caccgattgc ttatcaggta ttgtccgaac aggcatctgc tgtaacagct tatccaacac
      961 tcagtcaatt attagatagc tattatcacg aaaaagcaga gaaagatcgg gcaaaacaac
     1021 aaggcggaga actgattcga aaaatcgaaa atgaactaaa acgaaataaa aataaattga
     1081 aaaaacgtga acaaacactc aaagaatccg aaaacgctga gaattaccgt agaaatggcg
     1141 aactacttac tacttttctg acacaagtac cacgcggcgc aaaagaagtt gttttaccta
     1201 attattatga agaagatcgg ccaatcaaaa tagcactaga tccggcattg acaccaaatc
     1261 aaaatgcaca gaaatatttc catcgatacc aaaagctgaa gaacgctgtt aagctgattg
     1321 gcgaacaaat ccaagaagcc aaagatgaaa tccaatatct tgaatctgtc ttatctcaac
     1381 tggaaattgc cggcccaatg gatatcgaag caattaaaga agaattgact tcagaaggat
     1441 acctgaaaaa gaagaactta aaaaaacaaa aacgtaagaa accatctcag cctgatcaat
     1501 acttttcttc tgacggaacg ctcattcttg ttggtaaaaa caatcttcaa aatgaccagc
     1561 tgacaatgaa gacagctaaa aaaaccgact attggcttca tgcaaaaaat atacccggtt
     1621 cgcacgtcat cattaaaagt gacaagccct cagatgaaac aattacagaa gctgccgagt
     1681 tagctgccta tttttcaaaa taccgatact ctgcccaagt gccggttgat cttgtacagg
     1741 taaagcatat ccgaaaacca aatggcgcca agcctggtta tgttatttat gaaaaccaaa
     1801 agacgattat cgtgacacca gaagaagaaa aaattacagc tatgaaacaa aacaggtaat
     1861 caatgagtgt ttctagaatc atatttgcgt actttcccac aacagcaatt agttataaat
     1921 tgtttgctac aaaaagagga gttgtgacaa aattctgtca caacccctct tttttgatca
     1981 acggtgttca ataaacagcg ttctcatctg cttttcttag ctctgctggt ccagtaaccg
     2041 agtaagctct ttgataaatc tttgagcgat ttcactgagc ggacgtttcg ccgaataaat
     2101 gatataaaat tcatttagtt cgccttctgc caaagggatt aaccgcaagt gctcgcgaat
     2161 ccctccaatc acaataccag atcctgaagc gtaagcatca gtttcaagaa cgatattcat
     2221 caaagtacct cgatcactcg tataaatcac tgtttcttga tcagggatct cgataaggtc
     2281 ttcataaaaa tacgggaaat tatttccatc ctgtgtaaaa cgaacttgag gataagataa
     2341 caattcttct ttggtgatct ctgcgtgttc agctaatgga tgtccttgcc ttaaaaaaat
     2401 atgcgttttg aattttccaa tgctgcggcc acttagctct ccttgttgta aatatcttct
     2461 gataccagct tgattatgct cattcatata aataatgccg atctcactgt gctgctcttt
     2521 gacttcttcg atcactctcg ctgttgtcgt ctccatgatc cgaaattgtt tgatctcgtc
     2581 tttgaattcc tcgagtagct gtgcggtcaa aggacctaag aaatcataat gctgggcagc
     2641 gatcgaaaaa ttgtctctct tttcactcgt tagatagtga gtttctaatg tatcaagctg
     2701 gaccaatatt ttctcggcac gatttaagaa gtcttgccct tcttctgtta aatatgcccc
     2761 tcgattcgtt cgagtaaaca gcgtgatccc taactcggtt tctaattctt tgataccagc
     2821 tgaaagactt ggctgggaga caaacatttt ctttgccgct tctctgaaac taccattgtt
     2881 tgctacagcg accacgtatt tcatctgctg aatattcatt gctcaaactc ctcgaaataa
     2941 taaatttctc ttccattcaa gggctggatt ggtcggttgt tcggtcgagc atactgacca
     3001 tcgaagggga gaagaaactc ttggttcagt tttcctacat gatccattac aaaccattgg
     3061 attggcccgc tggtaggcgg agttgtcaat gagccaatat aatggaaatg gcttttttgc
     3121 tccggaaaga acacatccgg atttacccaa tgctcatgtt tttctaagtt ccaactttcc
     3181 ccattttctt gattatacag ccaaccttcc tgtaccatta gctggtacat gacacccaca
     3241 actagattct cttttttgct gttcatatga acaaaatgaa attcaatatc ttcctgtttt
     3301 ccgttgatga tatgttcaga aggcaagtgg aaatgaatat ctgtcaaata atagcgttct
     3361 ttcttgaact ctacataact gagttggtca aaaggtacta aatgaatcgt gtttttgaat
     3421 tccttgtcag taaaccgttg cttttgataa tgaaaggaaa gcgtgtctcc ttctattttg
     3481 gtttcttccc ccttggtcaa atgaataggc gactgcaatg gaaattccgc acctctcgca
     3541 aaccaatcac ataaactcgc ccaattttcc ggacctttgt ctccagaata gccccattcg
     3601 acatccatat tctttttcaa ctatacttcc ccctgcatct catatcattt ttatttttct
     3661 tctttcttta caatcgttga gacggtttct aaaaacgcct cttttccata aaattcctgg
     3721 ttcaatagtt ccggaaatat ctctttaaag aaatactgaa cagaaggccg atgttcaaag
     3781 cttttaatcg tagtcactgc ctcaatgaac atctccttat aaactttttc cgggttattt
     3841 ttgatgattt catcaaaaga ttcataaaga aggtcaacct tatctgaaat ggctaatagt
     3901 tctccttcta cggtttcatc ttttccttcg aacaaccgac ggcgataaac ttcttggaac
     3961 tcagctggaa tctcttggtt gatgaattcg tccgtcatct tttcttcaac tgtttgcagc
     4021 atccctctta actctttgct tgcgtatttc accggcgttt tgatatcacc aataaaacgc
     4081 tctgtgtagt catgattcaa tgatttttca tagagcagtt tccaatcgat cggttgtcca
     4141 ttcgcttctt caatgtctcc tagaacttgc gcaatagatg ctacacgata cgaatgtgct
     4201 gcaactgtat gctctgtata tttaaaaaat ccaggtgccc ttgtgatcgt ctctaaattg
     4261 ttcaatccta aaataaattc attcaacccc ataaaagtta cctccctttg agatttcttt
     4321 ttccgaatat catatcatta aataactgat attcgcaaca tttccgctct ttaccatttt
     4381 tgaaacagct cccttaccaa aaaatagaga aaatctatat ataatagaaa aaagagaaga
     4441 gattattctc ttctttctgc taaccagtct tagaaaaatg aattttaaaa aaatcaaaaa
     4501 ctgatcacga tagaagtttc ttttcatacc tgatgaaaag atgcttctcg caatcagttt
     4561 ttggattttt gctattccaa ttgatgattc tggagacaca aatcggattt ctctatcttc
     4621 atcaagcgcg cttaaatctg ccaattttca ggatcttttt tccattcttt tagcagagtt
     4681 aattcttgct catcgatata acgatcttct aaagctgctt caatcaatac agaataattg
     4741 gtcaacgtca taagagggat ttcggctttt tcgaaatttg cttttccttt tggcaactca
     4801 tacgtaaaga tagccgcaac accaaggata tccgcacctt ctctttttgc tgcttcagct
     4861 gcttccaaga cacttccgcc tgtagaaatc aaatcctcga tcacaaccat cttctgacct
     4921 tcaaatatac gtccttcgat ttggttacct ttcccatgat ctttcgcctt acttcgaata
     4981 tagaccattg gcaaatccag tatttccgct acccatgcgg catgagggat tcctgctgtt
     5041 gcagttccag caatcacttg tacttcaggg taagcttctt tgattttgct tgctaatcct
     5101 tttgcgatct cttttcggac ttttggatag ctcatcgtga ttcggttatc acagtaaatt
     5161 gggcttttga ttccacttgc ccatgtaaaa ggattacttg gatttaaaaa tactgcttca
     5221 atttctaata agtcttttgc gatactttgt tcaacattca ttttaggtta gctccattct
     5281 gtttgaatcg tttgatatgc tttataagga ttagttgact gagtgattgg tcgacctata
     5341 acgataaaag ttgagccgat cttttttgcc tgagaaggtg tgactactct tgtctgatct
     5401 cctgcgactg ttccttctgg tcttataccc ggagttaagc aaacaaattc gtctcctgcc
     5461 atttctttga tcgcttctac ttcccaagca gaagaaacca caccatctaa tcctgctttt
     5521 ttggcacagc tagcataatg gatcacactt ttttctaaag aaacttcgat tagttgatcg
     5581 gcatgcattt cttcttcact tgtagaagta agctgagtga tagctagaag tagcggacgt
     5641 tttccacctt ctggagtccc ctcttctaat cctcgcattg ccgcctccat catacgaata
     5701 ccgccagcgg catgaacaca ggtgagatca acaccaagct ttgccaatcc ccgcattgct
     5761 ttttcgaccg tattcggaat atcgtgaagt ttcagatcta aaaatacatt atgaccagcc
     5821 tcttttagat aacgtacgat ttcaggtcct tcttggtaga acaattccat tccgattttc
     5881 acaaacaatt tttcttcttt cgggaaaaat cgaagaaagt cttctacctc ttgcctagtt
     5941 gaaaaatcta atgcaataat tggtcgttgg tctagttgat tcatcgttca cgttcctctc
     6001 tcacttcttt gattaatctt tccagcgatt cgatgcctag ttcgctcatt cgcacaggga
     6061 gctctttaat tagtttagga cagatatacg gatcggtgaa attcgcggtc cctatagcta
     6121 cagcacttgc tccagccata aacatctcaa gaacatcatc cactgtctgc acgccgccca
     6181 tcccaatgat tggaaggctg gatatacttg ctacttggtg aatcaaacga atagcgacag
     6241 gcttgattgc tggtccggag agtccacctg tttgattggc taaaatcggt tttcttgtct
     6301 taaggtcaat ccgcatacca agaagagtat tgatcatcgt aaacccatct gcccctccag
     6361 cttcgattgc ctgagcgatt ggaacgatgt ctgttacatt tggggacaat ttgacataga
     6421 caggaacaga agaaactttc tttactgctt gtgttaattg aaaagcaaca tcagaatctg
     6481 ttccaaaagc aattccgcca tgtttgacat ttgggcaaga aatgttcagc tcgattgctt
     6541 tcacatttgg tgcttcgcca attttgctac aaacttctac atagtcttct tcacaagcac
     6601 cagcaacatt tgcgatgatg ggtaactcat tgtactcctc taattctgga agaagtttat
     6661 gcataacaac gtctagacca ggattttgca aaccaattgc attcaacatg ccagatggtg
     6721 tttccgccac tcttggcgtg ggattgccaa agcgggcatt tggagtcgtt gccttgacca
     6781 tgatcgatcc aagctgattc aaatcatagt attttccgta ttctttgcca aaaccgaaac
     6841 agccgcttgc cggcatgata ggatttttta attctaggcc aggaagtttg accgctaaag
     6901 gattctcatt catataatta cctctcctat tttaaaaatc ggtccttcgt cacaaacttt
     6961 cacacttttt gttcctgttt catcttccgg cgtatgacaa acgcaagcat agcaagcccc
     7021 tatcccacat gccatgcggg attctaatga taactggaca ttttgatgcg aagaaaacag
     7081 ctgttccact gtcttcaata acccgtttga accacatgca aaaacagctg taggttccgt
     7141 cttcgttcct aacaataaat taccgacatt tccgtgcata ccgtatgttc catcgtcagt
     7201 agcgattctt gtttctccta gacgattaaa ttctttttca taataaacga cttcatgtgt
     7261 ggcaaaacct aaaaaatgcg ttggcttaat tcctttttcg actaactgtt ttgataactc
     7321 atatagagga gggacaccga ttcctccacc gattataaat acttcgtctc ctgtatgaag
     7381 attggacaaa tcaaaaccat tgcctaaagg acccatgaca tctaaatggt ctccggcaga
     7441 aagagtagag aagactctag tcccctcacc ttccacccga taaatgatac ggcaagtatt
     7501 tgtttcgtgg tcgatatgat tcaagctaat cggtcggcgt aatagcaagt ctgcacgcgg
     7561 cacgagaata tgcaagaact gtcctggttg ctgcatttct tttactagat cacctttcaa
     7621 tgtcatttca aaaatctttg gtgccagctg tttttgctga acgatttcca tcatttcttg
     7681 tttcatctgt cccctcctgc aacggttttt cgtctttttg tcttaacatg tgctcgccgt
     7741 taaatagggt tagttgaaaa agcacgggat tccatcactc gaacgatcgc atctgctgtg
     7801 tctaaagaag taaacaatgg aataccatgt tcaactgctt ctcttcggat gatgaaaccg
     7861 tctttagaag catttccccg atctttatca atcgtattga caaccacttg tgttttacca
     7921 tctcttatta agtcgactac atttttttct gctgcttcct cagaaatttt cgctactgtt
     7981 tcaacgacca gaccattttt ttcgaaataa gcagctgtat gtttcgttcc tatcagacta
     8041 tagccaattt ctgtaaaacg tttagctaat tctagtgctt cttcttttgt ttcgtccgca
     8101 atcgtaaata atacggctcc atattcaggc aagtgtaatc cagaagcttc gaatgccttg
     8161 tacaaagctt tgtctaattg tctgtcagat cccattactt ctccagtcga tttcatttca
     8221 ggccctaagt aagtatcaac tttctgcaat ttcgtaaaag aaaagacagg tgctttaaca
     8281 tgaacttctt ttgtttctgg ataaagtccg ttttcataac caagtgtctt tagtttctct
     8341 cccaaaatag ctttcgtcgc aatttgtgcc attggaattc ctgtcacctt acttaagaat
     8401 ggaacagtcc gacttgctcg aggattgact tcgatcacat aaacctcatt ttcatggatg
     8461 acaaactgga tattcatcat cccgacacaa ttcaaaccta atgctaagcg gatcgtgtaa
     8521 tcttcgatcg ttttcttgat cgattcagat aatgtttgag gtggatacac agccattgaa
     8581 tcccctgaat ggacaccagc acgctcaata tgctccatga tccctgggat gagtactgtt
     8641 tcaccgtcac aaatcgcatc cacttcgcat tcaccaccaa gcaagtaacg gtccactagt
     8701 actggatgtt ctggagatgc tttcacagca tgttccatgt aatcttctaa atctcgctgg
     8761 ttttcaacga tttccatcgc acgtccgcct aatacatagc ttggacgaac aagaactgga
     8821 taaccaattc tcgaagcgat aaccacggct tcttctttac ttgtagcagt atcccctaaa
     8881 ggttgaggaa tatccaactc tttcagcgct tgctcgaata aatcacgatt ttccgcacga
     8941 tccaagtctt cgatcgttgt ccctaagatt tttacaccag cagcagtcaa aggttcggct
     9001 aagttgattg ctgtctgacc accaaattga acgattactc ctatcggctg ttctagctcg
     9061 atcacattca tcacatcttc gaaggtcaat ggctcaaaat ataatttatc cgaaatagaa
     9121 aagtcagtcg aaactgtttc aggattgctg ttcatgatga ttgcttcgta tcctgcctgc
     9181 tggattgctt tgacagaatg cacagtcgca tagtcaaatt caaccccttg tccgatacgg
     9241 ataggaccag atcccagtac tagaattgag ggcttttctg atcgtgaact ttcattttca
     9301 tattcatagg aactataaaa ataaggtgtt tttgattcga attccgctgc acaagtgtca
     9361 accatcttat atacaggaat caaatcattt tcttttctca tctggcgaac ggcttcttcg
     9421 tttatttccc acagctccgc cacttttttg tctgtaaaac cgttttgttt cgctgttttc
     9481 aatatcttgt catccaacgg ctgctgtttc aactgctgtt cgatttctac gatatgcaac
     9541 agtttatcta aaaagaataa atcgattttt gtcaaatccg ctaattcttc tatggtgtac
     9601 cctcttctaa tagcttcagc tacataaaac aggcgatcat cttgtgctcg aaccactttt
     9661 tggattaggt catcgtccgt gatgtctgcc aactcaggaa gttcgatatg gtgtgtaccg
     9721 atttctaaag aacgcacagc tttcaataaa gactcttcga tattccgacc gatagccatc
     9781 acttcaccag ttgctttcat ctgcgtgcct aaaagccgtt ctccgttttc aaacttatca
     9841 aacggccagc gaggaatttt agctacaaca taatctaatg caggttcaaa ttctgcaaaa
     9901 gtcgttcctg taacaggatt tttcatttcg tctaatgtta atccaagcgc tattttagca
     9961 gctagcttag cgatcggata gccagtcgcc ttacttgcta acgcagatga acgagaaaca
    10021 cgcggattga cttcaatcac ataataatta aaactatgtg gatcaagagc gagttggaca
    10081 ttacagcctc cctcgatctt aagtgctcga ataatcgaaa gagaagcatc acgaagcatt
    10141 tgatattcat ggtcagacaa tgtttgacta ggggcaaata cgatagaatc acctgtatgg
    10201 atacccaccg ggtcaaaatt ttccatattg cagacaacga ttgcattatc agccaaatct
    10261 ctcatcactt catattcaat ttctttaaaa cctgcaatac ttcgttcaat caaacattgg
    10321 gtagcggggg aaagacttaa tccattttct gatacgatac gtaattcttc ttcattttca
    10381 cacatacctc caccagttcc gcctaaagta aaggctggac gaacgatgac aggatagccg
    10441 attttatttg caaaatctac agcttcttct actgtattga cgatttcaga ctcggggatt
    10501 ggctgattca attctttcat caactgtttg aatagatcac gatcttctgc ttgatcgatc
    10561 gcagaaagct ttgttcctag aagttctatg ttcaattctt ctaaaatacc tgatgctgcc
    10621 agctccattg ccatattgag gcctgtctgt ccgcctaaag ttggaaggag agcatctgga
    10681 cgctcttttc gaagaatcct tgatacaaat tcaagtgtga tcggttcgat atatacttga
    10741 tctgccactt ctttatccgt catgatcgtc gcaggattag aatttactaa aaccacttca
    10801 tatccttctt cttttaaggc aaggcaggct tgtgttcctg cgtagtcaaa ttctgcggct
    10861 tgaccaatga tgatcggacc agatccaatc accataattt tcttgatatc tgtacgtttc
    10921 ggcatctgtt tactgctcct ttcctgcgtc catcatttcc ataaattcat caaataaatg
    10981 tagtgcatca tgcggaccag gggcagcatc tggatgaaac tgcacactga aagcgggata
    11041 atctctgtgt ttgactcctt ctactgttcc gtcatttact tctacatgag ttacgatgag
    11101 tttttctgga tcaatcgtgg cttcatcgac tgcatagcca tgattttgag aagtaaaatc
    11161 aattcttccg gtcgctactt ctcgtaccgg gtgatttaat cctcgatgtc cgaatttcat
    11221 tttataggta tctgcaccgt tggctaaagc aaataactgg tgaccgagac aaataccaaa
    11281 aatcggtact tttccttgga tttttttgat catttcgatt gcttctggca catcttttgg
    11341 atcaccaggt ccattcgtca gcatgactcc gtctggtgat agcgctaaaa tcgtctcggc
    11401 atctgtgtta tagggaagta ctgtgaggtt acagtttctt ttactcaatt ctcgtaaaat
    11461 actatgtttc aagccgaagt caatgacaat gactttccga cctgttcctg gacttggata
    11521 aggtttgtta gttgagactt gctgcacttg attggttgct agaacggttg ctttcagctg
    11581 atcaaatgca tgttcgaagg aatctccagc atcaactata ctagctttca tcgttccgac
    11641 ttcacggatt ttgcgagtaa gggcgcgcgt atcgatacct gatattccag gaattccttt
    11701 ttgtttcaaa aatgaatcta gcgtcatttg gtttcgccag tttgaagcta cacgtgcatg
    11761 ttcttttact actactcctt tgcatgttgg agaaatcgat tcataatcat ctctatttac
    11821 cccataatta cccaccatag gataggtaaa tgtaatgatt tgaccgttaa aactttgatc
    11881 agtgatagtt tcttgataac cagtcatact tgttgtaaaa acgatttctc cgaagacact
    11941 agcatctgca ccaaaagcct ttccttcgaa aactgttcca tcttctaata taagcaaacg
    12001 ttccatactt ttattctccc ttctgccaca caagttttcc gttgacaaaa gtcatttgtg
    12061 tttcgccttt tactttccag ccgataaaag gtgtattctc cccttttgat aaaaagtctt
    12121 ctttatcgat cgtgcaagtt tgtgtaatat caaaaactgc tacatcagcg ggggcaccaa
    12181 ccgttagcgt tcctgcattc aaaccaaaaa tctcagccgg tttaactgcc aaccaattga
    12241 tcacttgttc caacgtgaat cgaccagttt ctacaaaatg agtatagatc agttgaaacg
    12301 ctgtttcgct tcctacgata ccaaatggtg atttcatgaa actttggctt ttttcttcta
    12361 atccatgggg ggcatggtct gtagcgatgc aatcgatcgt accgtcaagc aagccttcga
    12421 tcaaagcttc tctgtcctcc cgtcctctta gcggcgggtt cattttccaa aagccgaaat
    12481 cttcgggaat atcttcgtcg atcaaaataa gatgatgggg tgaaacttct gctgttacgt
    12541 ggattcctgc tttttttgcg tctctgatta cacggacact ttctttagta gaaacatggc
    12601 aaacatggta atgaacacca gttgcttcag ctagcaacag atctctagca atttgagaag
    12661 actcggttac gcttaagatc ccgggaagac caagttcttc tgccttcttg ccagcgtgca
    12721 taacgccgcc aaataataaa gattcatctt ctgtatgggc tactagggct ttattgtttt
    12781 ttgcagcttc tttcatagcc agatacatcg tcccagctgt ttggacacct acaccgtcat
    12841 ttgtgaaagc aaaagcacct tcttcaatca gtgcttcttg atcaactaat ttctcacttc
    12901 gcagattttc tgtgattggc gcatactgca ataccttcac aactgcatct tttctaatga
    12961 tgtcatatac ttgtctcagc ttttctgccg tatcaggtac aggatttaaa ttcggcatcg
    13021 cgcatacagt agtgaaaccg ccacgagcag ctgagcgagt cccagcttcg atcgtctcct
    13081 tgtatgtaaa tcctggctct ctcaaatgaa catggacgtc cactaaacca ggtgtgatca
    13141 attgtccctt tgcatcaaac acttcatcaa attcggcttc tgagaatcct gtaccgattg
    13201 ctttgattcg cccatcttct atccaaattt ctgctggtgt cgtcatattt tttcgtgtat
    13261 tgatctgacc gtttttaatg agtgttttca ttttttcatc ctcctataat tacgcttttc
    13321 catttagcac tgcttctaag attgccattc tgacgaatac tccattgctc atttgctgaa
    13381 cgatccgcga ctgtaatcct tccactaatg aatcagctaa ttctacatca cggttaactg
    13441 gtgctgggtg cataatgatt gcatgttttt gcaacttctt cgcacgctca actgttaacc
    13501 catgttcctg atggtagcct tcttttgaga aactttcttt tccatcatgg cgttcgtgtt
    13561 gcacccgaag catcatcatg acatcaactt gatctagtag ttcatccaat ggcatataat
    13621 gtccgtacac ttcgaattca tcgtcgtacc attctctagg acctgagaag aatacttgtg
    13681 cgcctagacg ttttaacatc tgcatattgg atttagctac gcgagagtga gtgatatcac
    13741 ctacgatggc aactttcaga ccttcaaaat gaccaaattc ttcataaatg gtcatcaaat
    13801 caagcaagca ttgggttgga tgctgtccgc ttccgtctcc tccattgata atcgaacact
    13861 ggattgtttt actttgtatc agttcgtcat aatagttctc atcaccatga cggataaccg
    13921 ctacgtctac gcctaatgct gacatcgtca gtactgtatc gtatagtgtt tccccttttt
    13981 ggacagagct tgtgcttgct tcaaattcaa tcacttctag ccctagtttt ttctccgcta
    14041 catcgaagct tttatgtgtg cgagtactat tttcgaaaaa gaggtttgta gcaaagtact
    14101 ggcgcttttg cggagtccaa ttagcacctt gcttgaattc ctgccctctg cggatcaagc
    14161 ccataacttc ttgatcagta agtgcctcaa cggtcaataa atgctttaag ctgatacgtt
    14221 ctgatttgat gatcataatg tttcctcctt agttttcttc gcttcgtgaa gtttctggta
    14281 agataagatt taaaatgatg ccaagtacag ttgctaatgc cattgccgac aatgtaaatg
    14341 tgcctacttc aaagacgagt ccgccaattc ctactactaa gataactgaa gcaatcaaca
    14401 gatttttctt tttatcaaaa tcgattttgt tctcgattaa aatcttcatt ccacttgcgg
    14461 caattactcc aaataagata aaactgattc ctgagatgac tggtccaggg atacttaaaa
    14521 tcaaagcgct taattttcct acgaatccta aaatgactgc aaatactgca gctccaccga
    14581 tcacaaacac gctatggaca cgtgtgatag ccagaacacc aatgttttca ccgtaacttg
    14641 ttacaggagg acctccgaca aaggctgcca cgatttgtgc taatccatca cctgtcaacg
    14701 tcttatgaag acccggttct tcaaagaaat tacgtttagt tagtttattc aataccataa
    14761 gatggccgat atgctctgtc atcgtcacaa aagcgatggg tgccattgtt gtgattgctc
    14821 caagatatag ctttggttca tattgtacaa agggaatctc aaagttagga acagcaaacc
    14881 aggcagcgtc tacgattggc ttagtatcca cgattccaaa cagcaaggct acgatgtatc
    14941 cgctaataat acctagtaaa atcggaatca atccgagaaa acctcttagc cacatgttga
    15001 agaaaattgt taatcctaat gtgatcagcg ctacagcaat atacttgaaa tcatacgtgc
    15061 cctgattata catagcattt gttgctgcat ttgccgcaag tcccaacccg ataaccatga
    15121 tgactggacc gacgacgatt ggaggcaaga ttttatccag ccatgctgaa ccgatctttt
    15181 tgatgatcag cgcaacaatc aaatagacta atccagttgt gactgctcct tgtgcaatcg
    15241 ctggataacc atctgttttc atcaaaagct gcatcgctgc aatgaaagcg aagctgcttc
    15301 ctaagtacgc aggtatcttt cctttagtag taaataagta caccaatgta cctagtcctg
    15361 aactgactag cgcaatacct ggatcgatac ctactaagat ggggactaac acggttgctc
    15421 cgaacatcgt gaacaagtgt tgtaaactta atcctaccca atgtcctggg gttgggcgat
    15481 cgtggatatc taacaccacg tcatcattat gaaatccttt tttctccgac atgtttctct
    15541 ctcctctaat cttcctcttt caaaatcatg atgcgatctt gtccatcaag ctcttgcatc
    15601 tctactaaaa tctcttccgc ccgagatgtt ggaatgttct tcccaacata atctgcacgg
    15661 attggcaatt ctcgatgccc acgatcgacc aggactgcta atgaaatttt tcttggtctg
    15721 ccaaaatcca ttactgcgtc cattgctgct cgaatcgttc gtcctgtata caaaacatca
    15781 tcaatcaaaa taacttcttt tccttctaag gaaactggga tgtcagaaga atgaagttcc
    15841 ggttcttctg gattttcttt tttgtcatct cggtataaag tgatatccag ttctcctaca
    15901 ggaatatcga tatcttctag ctgcttcagg cgttcggcaa ttcttgatgc aatgtagatt
    15961 cctcgtgttt tgatacctac caatacgata tcttggatac tatggtttct ctcgataatc
    16021 tcataagtaa ttcgagtcaa tgctcgcttc atggttacct gatctactac ttcttttgct
    16081 tgcattttca ttccccctac ttttttgcat aaaaaaactc ctgccctaag aggacaggag
    16141 gaatgtttag actgagcgta tactgataca ctgatagcta tactatgtca atgagcaatc
    16201 tacttatggc gcaccatacg tatccttgct cccacccttc ttagcctcac gggactaaac
    16261 ttaaaggaat tctattaagt tttatgcttt cgttgttaat tactataccg ttatctaaat
    16321 taaaatgcaa tgttttttct taatttttct aaagtttttt caaaaacttc tggaagaggt
    16381 gcttcaaaga tcatcttttc gtttgtagtc gggtgcgtaa aacctaacat ttgcgcatgg
    16441 agaaactgac cattgccttt caaagttttc ttcggtccgt atactggatc tccagctaac
    16501 ggataaccga tatacttcat atgcacacgg atctggtgtg ttcttccggt ttctagtttt
    16561 aattcaacca gagtaaatcc ttcgaaacgt tccaatacag taaaatgtgt gacagccgac
    16621 ttcccatctt ctcttatcgc ctgcattttc cggttttcct tcgaacggcc gattggcgca
    16681 ttgatggttc ctttttcgtg aggaatctct ccatggacta aagcaacata tttgcgcaaa
    16741 gaggtcttat cttttaattg ctgagctaat gattcgtgtg cctggtcatt tttggcaacc
    16801 attagcagtc cggaagtatc tttgtcgatt cggtgaacaa tacctggacg aataacgccg
    16861 ttgatcgtag aaagatcctt gatatggtac atcagcgcat tgaccattgt gccatgcgta
    16921 tgacctgctg aaggatgaac gaccattcct tgaggtttgt ttatcaccgc tacatcttca
    16981 tcttcgtaaa cgatcgtcaa cgggatattt tctgggacca catctaatgt ttctggttcg
    17041 gggatcaaga cagtaatctc gtctccttgt tttactttgt aatttgcttt gactggctgt
    17101 ccattgacag aaaccgctcc atttttcagc cacagctgaa tttgcgaacg actgtaatcg
    17161 gtgaataaat tagtcaatac tttatcgatc ctaccagatt catggtgaat cgtcgtttta
    17221 agttctgtca tttttttctt tgatcctttt catctaaaat aatataaatt aacatacaaa
    17281 tcactccaca tacaagtgtc acatctgcta cgttaaaaat cggaaagctc ataaaatctg
    17341 tctggaacat atctactaca tagccaagac gaatacggtc gataaaattg ccaatcgcac
    17401 cagctagaat caaactcaat ccaatcatga accagcgatt acctttttca cgatttttaa
    17461 tcatcaatgt gagaatcaca acgactgcaa tgagtgtcac tatagtaaag aaccacatct
    17521 tcccttctag catactccat gcggctccag tgtttcgaat atgattcagt gacaaaatac
    17581 ctggtataag atttttcgtc tctccaagcg ctagattatc agtgatccac catttgacca
    17641 actgatccac tcctactagc aaagcgctga atatccaata aataattaac aaaaaatcaa
    17701 tccttttcta tttgtttata aatatcacga ggtcgtacga tcccgagcag attaccatcg
    17761 ggattcccat ctttagtgat aagtacggct tccaaagtcc cttgctcacg aaacatcgct
    17821 tcaacctcgt aaatatgtgt tttagctgga acaaaatgat aatttgtgta ctttccgttt
    17881 tggatgatca aatccaacgc tcgtttattt gttaaatcaa ccggaccttt ttggctttct
    17941 tttgctagcc aaaacccgat attacgtaaa gtaatcaatg ctacaaattt tcctttattg
    18001 tataacggaa attgtgaata ccttttttct gctactatct ttaacagttc aagtaacgga
    18061 agatcttgtt caaaacctgt tacacgtttt gcaaatcgag gcagcacggt ttcaggctga
    18121 atcagttctt gttcgatcag ctggattcgc ttgactgtcc aatcatttgg ctctgcaatg
    18181 acaaaatcga ctgcgatccg atcatggacg atcgcattcc ttaactgagc aagctgtaaa
    18241 agatcatctt cgtattttct gatcattaat tgttttcttt gagctaggcg tctgacaagt
    18301 tcggtaaatc ccatatttcg tgcatttccc atctcgtctc tcatccattt ttcgattcga
    18361 ttgaaactga ttaaaaaaag atcagagttt gccataattt tcctccttga tcaaatatgc
    18421 ccggtttttt atatagaaaa agaacgcaat caacacaata actgcaaaaa aactgaaaaa
    18481 taaattttgt aggaaaacgg cccccaaccc agttgctaga aataaaaacg gatagatttg
    18541 aagaatcaag taattcattg tgatcacata agcaggcttt gcttctttca ctgtataaac
    18601 ggggcttttt agccaataaa aggtgacctg catcgtaaag ggcacttcca gatcaagcgt
    18661 tatcttttgt tcatgactga gaacactgcg tttttcattg ttgattctta gctgaatcga
    18721 gctacccata ccgtaaaaac cggtttttct tataaatgtc gttttcatca taccctccta
    18781 ttatgcttta gtatagctca aaatacaata aagaaaaaga atgatcctag tgtaaacaaa
    18841 attaattccc tatcgtctaa aaaaagaagc tgtagtcaaa atacagctcc ttcgatggta
    18901 gattataatc aagcttaaaa caatcccaac acttctccgt catttgtcac gtccatattc
    18961 aatgcagcag gttttttagg caaaccaggc atcgtcataa catctccagt caaggctact
    19021 aaaaatcctg cccctaattt tgggatgatt tcgcggatcg tgatggtgaa atcttccggt
    19081 gcacctagca gtgaaggatc atcagaaaat gaatactgtg tttttgccat acaaatcggc
    19141 agtttgtccc atccattctt cgtaaactct tctatttgtt tttgcgcttt tttgctgaaa
    19201 acaacaccat ttcctccgta aattttcttg acgattgttt ctgtcttttc ttgtatcgtt
    19261 tcttctaggc ggtataatgg cttgtaatta gcttcttttc tatcaatcaa tcgtactaca
    19321 gcttttgcta aatcaacgcc gccttctgct ccatctgccc atacactcgc tctcttggca
    19381 agaatcccct gattttcaca caagtgctcc aacagtgtga gttcattgtc tgtatctgtt
    19441 acgaattcat tgattgcgac gatcacaggt agctgatatt gttccatatt acgtatatgg
    19501 cgctttaaat ttgcaaaacc tactttcaaa gcatcaagat tctcattttt aagttcatct
    19561 tttttcattc cgccatgcat tttcaatgca cggacagtgg cgacaatcac cacagcatcc
    19621 ggcgcttttt tcaagttagg tactttgata tctaaaaatt tctctccgcc aagatctgca
    19681 ccaaatcctg cctctgtgac aacgtaatct gctaatctca atgctgtctt ggtagctaaa
    19741 atactattgc agccatgagc gatattggca aacggtcccc cgtggacaaa agctggtgtt
    19801 ccgtaaattg tttgtacaag attcggcttg attgcatctt tcagcagtaa tgccagagcg
    19861 ccttctgctt tcaagtctcc agcagtcaca ggctgacggt caaatgtata gccgacaacg
    19921 atccttgcaa gacgagcctt taaatcttca aggtctgccg caagacacaa gatagccatg
    19981 atttcgctgg caactgtgat atcaaaccca tcttctcttg gaacaccttg gattggccca
    20041 cccaagccaa caattacttt acgcagttca cgatcattga gatcgactac ccgtttccaa
    20101 atcactcggc gggcatcgat gttcaattca tttccttgat gaatatgatt atctaaaaga
    20161 gcagataatg cattattagc tgttgtgata gcatgcatgt caccagtaaa atgcaagttg
    20221 atatcttcca taggcaatac ctgtgcatat cctccgcctg cagcaccacc tttgattccc
    20281 atcacaggac caagtgaggg ttctcgcaat gcaataacag attttttatt gattttattg
    20341 agcgcgtctc ctaaccctac agtgatcgtt gactttcctt cgccagctgg tgttggattg
    20401 atggaagtaa ctaagatcaa atgcccctca gcgttatcct ttgatcgatt gattccagaa
    20461 aaattgattt tcgccttata tttcccatac agttccaaat cgtcttcctt aagatctaat
    20521 ttactagcca cttcaacaat cggttctagc tctgtttctt gtgaaatttg cagatcattc
    20581 ttcatttgat tacccctttt cacgaacttt attcaacaaa atatcttctt tgttaagata
    20641 tgccaattat accttttttt attcagaaaa aaaacataaa attacaggtt tttaatttat
    20701 ttgacgtact tataaatact ctttataatg aaggctatga tcagacttta gaaaggtcgt
    20761 gagtgctttg accacaggaa ttgtaaaatg gtttgacaac aaaaaaggat acggctttat
    20821 cagttatgat gacacagaag aaatttttgt acattttact gcgattgaag aagagggatt
    20881 caaaactttg gaagaaaatc aagtggtcga atttgagatc atcgaaggga atcgaggaac
    20941 acaagctgcc catgtcaaga aaggcaacgt tcagactacc gatactagta tgcatgaata
    21001 gataaacaaa tagagtgaga cgctaaacgg gatgaaccgt acgtctcact cttttctttt
    21061 cctgtaaaaa ttcgtttttt taggttctga tttttaaaat tagctttttc tttttttcgt
    21121 ataaggataa ggaattgatt ctgatttggg tccgtttttt tcaaaatgat caaaaaggac
    21181 tacttgatct ttttttcgca tcatgaaaac agatggggct ttctcatctt gcaacatcat
    21241 ttgcacccca gtattagttg gcgtcaaaga tcgaatctgt ccgacagata tttctcggtc
    21301 tttccaaaaa gcagcataac gtataatcac agagtttgat tttaaaataa aagaacgccg
    21361 caaacctaga aatagaaaaa caagaaaaat acctaaaaca aaattgcttt tccaataagg
    21421 acctgtgttt tctaaagaaa gaatcagact aaaaaacaga atgatcaagg tcaatgacca
    21481 atagatgatc gtatgtgcca gttcaggctg ccatcgaata ttttttttca ttctctaacc
    21541 tctcaccgat tcagtaatga tataatctta ccataacatt agtttgaaca aaaaggagaa
    21601 tctcttttta tgttaaaagt atacattgat gcctctacaa aaggcaaccc tggtcctagt
    21661 ggaggtggaa tcttgattgt ctatcaaggt aaacaagaac agctatctat cccgctttct
    21721 atagggacaa accatcaagc agagttcgaa gtctttttaa aaactttaga atttctaaag
    21781 aaaaacgact tacagaatga aacgattttc tgtttttcag acagcaaaac actagtttct
    21841 acggtcgaca aaaacgcaac gaagaacgag ctcttccttc cctaccttca aagaatccaa
    21901 gaacttctat ccgaattttc tttattgatc ctgcaatggt tgcccgaaaa caaaaataaa
    21961 ggagcagata atcttgcacg tcaggctctc cataaacaat taaaagaaaa aaagactctt
    22021 taaattaaaa actttaagga gtctttttat agtttctcat ttaatataaa agataattgt
    22081 gatcaaacgt aatttccaat tggtaatctc cgattttttc ttctatttga ctacgtaaga
    22141 ttctttctag ttctgtatca acaaactgga atttctcagg gaccactaca tcaaattgca
    22201 gcgtttttcc ttgatgaatt actctaaaat catgaatatt aagccctgta cctgtttcaa
    22261 gaagaatttg ctttaactgc cgcaagatat tatagtattt ttcgttatca acaggcattg
    22321 gatccaagtg acagacaagt tccacatcca aagacttttt aaagtctttt tctatcagat
    22381 caataatctt atgagccaca ttcaaattca ttgattcatc tacttcgatg tggactgatg
    22441 caaagcgttt attgggtcca tagttatgca ccaataaatc atgatagcca agtatatcat
    22501 cgcaagcatt taaatgctct tccatttctt caatctctgc tggcgttggg cgacttccta
    22561 atagttcgta tacaaaattt cgaagcatcg tcaatccact ataaaggata tataatgcta
    22621 aagcaaaacc tatatatcca tcaatacgcc atccagttac ccattcgatt gctgctgaaa
    22681 gcaatacagc cagtgtagta aagacatcat tataactatc tgttgctgta gctctcaatg
    22741 tttcagaatc aatggattgc gcaataacct gatacatttt gccttgtgca aatttcaaaa
    22801 agatggaaat gattaggaca aaaaagacga tgggtgttaa agagacattt tctggatgga
    22861 tgattttttc agcagaagac tctaaaaatt gaaatcctac ataagtaatg atgatcgaaa
    22921 caaataaccc actgatatat tcgaagcgtt cgtgtccata aggatgttcc tgatctgctg
    22981 gctttgcagc aattttaaat ccgatcaaag tcaatatgga tgaagcagta tctgatagac
    23041 tgttcactgc atcagccata atggagacac ttcctgaaaa aagcccgatc attagcttag
    23101 agacaaacaa gatcagattc gtaaccaatc ctaagatacc cgctagtact cctttttttg
    23161 tccgctgttg cggtatttgt ttcttttttt cttcttgttt cttagccaag ttttttaccc
    23221 cttctagttt gcttgttgct caggtaaaaa gatggagagg acgattgttt tcctctcctc
    23281 tcttcctttt tctatctatc gtgcgtccta ttactattaa aagatggtca ttattctggt
    23341 ttcaacggtg ttgctgcaaa taacgctttt gctagtaatg gtgttatgat tcccgcacct
    23401 attgcttctg gtatcccatt gattgctgca acccctgcta aggttttaaa taaaagagca
    23461 gagtctacac cataggcatc tgccgttgca cctgtataaa ataatcccat gaatcctaac
    23521 actaagactg tattgaccaa tgaacccagt acccctgcaa aggctgagct gatcgttatt
    23581 gatttatttt tttgataaat ccagtggaaa accaagcctg ctactaagcc aacaagtact
    23641 ctgggaacta ccgagataat cggattcgtg aacactaatg tatcaaatgg cgttgttggc
    23701 atggcatagg cacgaacaat tgtagcgatt ccccaaaaca agccaatcac catgccatct
    23761 tttgggccta atactactgc agcaataatt actgtgatat ggataattgt taaactaatg
    23821 aatcctaatg gaataaaccc cagccaagga accatcgctt gtacgatgat gattgctaac
    23881 aagatcgcac gtaagactag tcgaaaggtc ttatttctac tattcatttt ttcacccctt
    23941 tttatttata ctaatcgtaa aaatttctgt cactttcgtc aactaaagac catccgaatc
    24001 cgaccatttg attagatgcg ccatccaatt gaaaaaagta tgagggcaag acttgtttgt
    24061 cttcgccccc ataatcatgt ttcgttcaat gtttgaactt ttgtttttct gtcaaacgta
    24121 aacgccctat tgttgcgcaa cccattcttt cgcagcttta agtgcatctg gaataccagc
    24181 aggatttttc ccgccagctt gtgccatgtc tggacgtcca ccaccgccac cgcctacttt
    24241 cggtgcgatt gctttaatca agtcgccagc ttttagtcca gcttcatttg attctttcgt
    24301 cattgccgct agcagactga cttttccttc ttgttcgttt gctaaaacaa gaatatctga
    24361 aatatttttt tgtttccatt ggtcagctaa ttgacgcagc tgattcatat ctttcacttt
    24421 tacttgtgct gcaatgattg tttttccatt gatcgtttct ggatctttga atacatcacc
    24481 agcttgttga ttcgctaact tgctagctaa ttgttcattt tccttttgta gctctcttac
    24541 ttgctgttgc aattgttccg cttttgaaac aacttctttc aattgaggtg atttaacaat
    24601 tgttgctact tgttttagtt gtttttcttc ttcttcaagt agttcgtacg cttctttact
    24661 tgttacagcc tcgattcgtc gcacgcctgc accaattcct gattcagaaa cgattttgaa
    24721 gattccgatg ttttctgtat ttgctacatg tgtgcctccg cacagttcga ttgaccagcc
    24781 gccaatattt actactcgaa cgtcatgtcc gtatttttca ccaaacaaag ccattgcacc
    24841 catgtttttg gctgtatcga tatctgtttc aattgtttca actgggatag cttcccagat
    24901 tttttcgttg acgattcttt ccatttcagc taattcatct gaagtgattt gaccaaagtg
    24961 ggtaaagtcg aatcgtaaat gtccaggagc gactaaagaa ccagcttgat ttgcatgctc
    25021 gccaagtact tctttcaatg ccttgtgcag tagatgggtt gctgtatggt ttttgatgat
    25081 ccgattgcgc atcgattgat cgatcaatag atgataggtt tgtccttcac tcattggtgc
    25141 ttttacttct acggtgtgca taaattgacc attaggcgct ttttgaacat ctgtaacaac
    25201 tgctacgatt tcgcctactt cattcatgat ccatccttga tccgctactt gcccacccat
    25261 ttctgcatag aaaggtgttt gatcaaagat catttgagct tcaccttctg cgacttcatt
    25321 caaaagagac tcacctttaa cgatgaccaa taattgacta tctgattctt gttctgtgta
    25381 tccaatgaat ttactttcta ctttgatatc tgtcaataaa gcagattgta cccccattga
    25441 tttttcagta ctgcgggcag agcgagcacg ttcgcgttgt gcatccattt ctttttcaaa
    25501 accagcatga tcaactttca gtccttcatc ttctgccacc tcttccgtta attctaccgg
    25561 gaagccatat gtgtcgtata gtttgaagat gtcttttcct gctagagtcg tcccgttttc
    25621 gttttttact tcttggatca cttgatttaa gatttccaaa ccttcattga ttgtttcatt
    25681 gaaacgttct tcttctgtac ggataacttt ttcaataaat tctttttgtt gaagtacttc
    25741 aggataataa cttaccatga tttccccaac aacagggact aaacgatata agaatgcttg
    25801 ttcaatacct aattttttcc catgcatgac agcacgacga agcaaacggc gtaagacata
    25861 ccctctccct tcattcgatg gcaatgcacc gtcgccaata gcaaatgaaa gggcgcgaat
    25921 atgatctgcg attactttgt aagaaatatc tgttactggg ttttcaccat attttacttg
    25981 tttgcttagc ttttctacgg cgtggataat aggcataaac aagtctgtct caaagttcgt
    26041 tgacgcatct tgaacgattg agaccatgcg ttccaatccc atccccgtat caatgttttt
    26101 atgaggaagt ggttcaaatg tgttatcagg cttatggttg aattctgaaa atactaagtt
    26161 ccagatttct aaataacgtt cattttctcc tcctggatag ttttcaggat cgtcttctgc
    26221 taaatcgtta taagcttctc cacggtcata gaaaatttcc gtatccggac cacatgggcc
    26281 tgcaccgata tcccagaagt tgtcttctac atcaataatg tgatctagtg gcaggccaac
    26341 ttcttcatgc cagatgcgtt ttgcttctgt atcttttgga taaactgtta cataaagttt
    26401 ttctggatcg aatgccatcc attttggatc agtcaaaaat tcccatgccc agtggatggc
    26461 ttcatttttg aaatagtcac caatcgaaaa attacccagc atctcaaaca tcgtatggtg
    26521 ccgtgctgtt ttaccgacat tttcgatatc atttgttcga atagattttt gggcatttgt
    26581 gattcttgga ttttctggca caactgaacc atcaaaatat tttttcaatg ttgcaacacc
    26641 agagttgatc cacaataagg ttggatcgtt cacggggatc aaagacgcac taggttcaat
    26701 cgtatgtcct ttagattgga agaaatcaag aaacatttgt cgaacttgtg cactacttaa
    26761 ttgtttcatg tcattacctg ctttctataa attaaataca aaaaaacacc atcacagcca
    26821 aggacgaaaa ctcgcggtac caccttgatt gcaatgatgt gtaatcatta cctcttaaac
    26881 tcgataacgc tgagctgcgt cggtatttct accaaaatag aaaaagggag caatttgatt
    26941 agtgactatt cttttttcag ccaagaaaga attttctgtg agtcttaaaa aacaaatcat
    27001 atccttttcg tacttaatta gtatacgcat tctattgatc actgtcaata tctcaatttt
    27061 tattttcatt tccttttggt catactccac gatttttggt acgataagaa taaaggaatc
    27121 aatacatctc tgctattcat gacaaggagg aatatgatga aaaaaatagt tggagcggat
    27181 gaatggatac gcgcagctag ctgctttttg agatatcaag tttttgtatt agaacaaggg
    27241 attcctgcag aactagaatt cgacggaaaa gatatcccgc aacaaaccta ttatctattt
    27301 cttgatcaaa aaagaccagt agctactttg cgttatgaaa agaaaacacc tacttgcttc
    27361 aagccggaac gattttgcgt agcaaaagaa taccgaggaa aagggttagg cggtcagttg
    27421 cttgaagctg ctgaaaaacg ggcggtttca gaaggttgtc agactagtta tgtagtagct
    27481 gaaatgacgg ctgtagattt ttatgaaaaa caagggtatc atacttgcac agaacctttt
    27541 attgaagatg aagtactttg tatcggaatg aaaaaaagtc tagcttaaaa acaagagatt
    27601 gtgacacgcc ttttgtcaca acctcttgtt ttttatttat gtgaattttt cttattttta
    27661 cgagcagtac ggctttgctg tctgcgttcg attttgcgtt cttttttatt tttttctgca
    27721 attgcccaat cgattttttt cttataacca ggcttgatct ttttcttttt cttcttcaca
    27781 agaccaatca gcgtgggatc taatacatct tttgattttt ctcgtttggc acgtctatta
    27841 cgatcgtatg ttttgacgat ttccccgttt ttgatttctt ttggttcaaa tgagacgccc
    27901 aatttttcta tcgcatcaat ggcttgctca tcatttggcg aatataacgt aatggccgtt
    27961 ccttttaagc cattacgtcc agtacgtccg acacgatgga taaagaagtc tagatcttct
    28021 ggaatttctg cattaataac atgagagaca ccttcgatat cgatccctct agcagctaaa
    28081 tcagtcgcta caacatattg atactccaga ttctgtactt gtcgcatcac tcgttttctc
    28141 tctcttgggg tgatgtctcc atgaatcttt gctactttca agccttggtt tttcaagtaa
    28201 tcggcaattt catccacatg ctgttttgta ttggcaaata cgattgctaa ataaggatga
    28261 ccaattgtca gcagttgata aatcatttga ttctcatctt taccttttgt tgaaatcagc
    28321 caattttcaa tgtcttcaga aataactgct tttggtttga tttcttcaat gattggattt
    28381 tccatgtatt ttcgtaagaa tggacgaagt ttttctggaa tagtggcaga aaaaactaaa
    28441 aactgcagct tttctggtaa tcgacttgca atttggtcta cttcatttaa aaaacccata
    28501 tccaatgtca tatccgcttc atcgacaaca aatgcaaatg cggtgtgaat cttcagcgct
    28561 tgttcattca tcatgtctaa tattctacca ggcgtgccta ctacaacctg tggctgttgg
    28621 tgatgcagac gatttaattg acgctgtttg tctgtaccgc cgacaaaatt cgagacacgg
    28681 atctccggtg tagaaaattt agcgatttgt gtagctgctt catagatctg tgcagctagt
    28741 tccctacttg gagctgtaat aacaacttgt acttcctctt tttctgcatt gattttttca
    28801 aacaaaggca acaaaaacgt atgtgttttt cctgtaccag tttgagattg cccaatgata
    28861 ttttttcctt ttgcaattaa aggaatcaaa cgttcctgga cctctgtggg ctgtttgaag
    28921 ccctttgcgg ttaacgcttc attgataaac ggtttgaagc ggaatatatc aaaattattc
    28981 attcgtgcac ctcttctctt taaattatca cgactttggc attataacac agacaaagcg
    29041 tttttgctca gctaatttcg agaatcatca tcctttgttt ggccaatcgt gctaacagta
    29101 tatgtgtgac tagctttttc ataaaacaga atccgttttt ttctcaaaaa tgatagcaag
    29161 atatttaaaa taaaaatacc ttgtagtaac aagacaccga gagaaatgaa tactgcactc
    29221 atctgcaaca ccgtattcgt tgtcgaattc atgatttgct gaagcaactg ccccaaccag
    29281 cttaaaccat aaaaaagaaa gtacagatac ccgtagcgga tcatcaatgc ttttaaagaa
    29341 attcgttcgc ggtcttcttc caccaaacgg atacgcacaa tttttttgcc aagtgtccat
    29401 ccattggtta taaacggtac aatcataaag tataccccta cttctaataa aagccaccag
    29461 atatgagaag taactgcccc tgaatcgaac gcaattttaa agaaaatcgc cgctaccaaa
    29521 ttaataagag ataaaaatgt ccagtcgatc aaataagcga ccaagcgtcg agtcaatgag
    29581 acagtctttc ctttttcata agaaagttca tccattcgtc ttcttgtagg aagcataaat
    29641 gtaaataacg gcgtaacgac aaaaccaatg attccaccca atgtatttgt cactaaatca
    29701 ttcacatcaa ataagcggta tggtcttggg tagataaaat aaagtccact tagctgcgtc
    29761 aattcaaaaa atagagaaag gcagaaacta gcaatcatcg ttttcataaa agaaagccgg
    29821 aaataatatc ttaaataaat gccaaacggt atgagtaata aaacattaaa agctggttcc
    29881 aaaaatacac tctgcttcat tgccggcagg taggtactag gttcagacaa gaccaatacc
    29941 gtgttgtctc tgaaatgttg ccatgaagca aataaatgca gctccatctt tggccctgtc
    30001 atttgggcaa ccgtctcctt tgccggaagt ggtaagatca ccaaaaaata cgcacacaat
    30061 aaataaaaaa cgaaagaata caaaataact gcccttgtta ctagaaatgt tccatacttt
    30121 cgatattcat aaataaaaaa aacagatgag atcgctaagg ctaaaaatgg aaaaacaatc
    30181 agcgcaaaac gaatcggttc gatataactt gccatatgac tcctccttga ttctttgtat
    30241 ctctcttatc ttagcagtcc tttgctgttt caagcaagta acgaggctat tatttctcat
    30301 ttctttcaaa gtaaagtaag ataaacacaa agggggtgtc gagatgctga atatgtactt
    30361 tgtttttggc gtacctattt ttttactgtt cctttatgct acgatcgctt atgtaagaaa
    30421 aagaactaca attcattatt taggatttat tctcctgatt atttcgggtt tcatgctagt
    30481 cttcaatctt cagacttggc agcaagcact tcttgaaatg gataaaatga ctccacatgc
    30541 tttgtctaaa gtgcttggct accctgtcta tctgatttgg cttcccattt tcatttctgg
    30601 ttgcttggtt ttattaaata tttatcgcgg cgtacgccga atagttcagt tacgcaaatc
    30661 aaagtaaaag acagaaatcg gttgagcccg atttctgtct tttactttgc tatttcatcg
    30721 tagacaaaac gacatttacg tgatcaaaat taacgagtac ttttgacatt tcttccacgt
    30781 actcctcatt taaataaaat attttgtttg gcagagaagt gcagttctaa taaaattcga
    30841 atgttttagc tatctacgtt ttaaatagag ataaatcggg ataccagcaa gtgtcaatac
    30901 tatccccatc gaagctaaaa aggtctgagt gataagcgtg cttgatacga taaaagtccc
    30961 tccaatgatt gctactagtg gaataaacgg atacattgga actttgtatg gtcgaaacaa
    31021 atcaggttct tttttacgaa gaagaatgac accaacaaag accatcgtat aaaaaatcca
    31081 aatgacaaag atcagcatat ccgttagtgt atcaaaacca ccgatcatca tcatgccaat
    31141 agcgatgact agctctaaga tacctgcggc tacaggaact ttagttttat catgaagttt
    31201 agcaaagagc ttgctaaaag gcaggttgtt ttcttttgcc ataacataag ggagacgcat
    31261 tccagtaagg gtatagccat tgatggttcc ataaacagaa atcaagatac caactgtgac
    31321 cagtcttcca ccgaagccgc caaaaatcat ttttgcaacg tcacttgccg cattgctgtt
    31381 tcctgcgact ccgtcgatag atgcggttct taagaacacc gcatttacta ataaataaac
    31441 gatcatgatt ccgatgattc ctaaagaaat tgcttttggc aaatctttcg ccggcttttt
    31501 caattctccc gaaatatttc ctacgtgtat ccaaccgtcg tatgcgaaca tcgttgctag
    31561 caagcccgct cccaaggctg agaaaaatga aagattttct cctgcttgga tcggaaacag
    31621 ttggaagtct actccttctt gtcggaacaa accgaaaatg acgatcacaa acaaaggaat
    31681 aagcttgcag acaagcgtaa tcgactgaaa agcccctcca gctttagaac ctaaaaaatt
    31741 gatcaacagg atcgatacag cagctgtaac agctacggga acaatcattg actgggaaag
    31801 accaaataga ttgacgaact gtgtaccgaa aatgatcgac aaggctgcta catttgctgg
    31861 aaaataaatc acgacttgcg cccagcccaa taaaaaagct gctgtatttc cgtaaatccg
    31921 ttcgatatat ttaatcatcc ctcctgtttc tggaatagca gctgccagtt cagctcctgt
    31981 tagtcctgca cagacagaaa tcataccacc gagaaaccaa gaaaacatat gcaaactggc
    32041 ggatcctgta acttctgcta cgcttgcggc tttaaaaaat acccctgcac cgatcactgt
    32101 gcccataaca gtcgataaag cagtaaaaaa tcccatcgta cgttttaatt cattttctat
    32161 ttttacttct tttactggcg tggcttgata ttcttccatc ccttgtcccc tttcatacca
    32221 tagccaatcc caaaagtata aaaaactttt tggatgtggt tcttgtttta taccgtctct
    32281 accaattttt ctttcagttt ttccaacata tcctttgtca tcacatctaa gtcgtatttc
    32341 ggcgaaaagc cccattcctc ttgcgcacaa gaaacatcta gtgaatttgg ccaagattct
    32401 gctattgact gacgtacagg atccacatca taatccattt caaaatctgg tatgattttt
    32461 tgaatagatg ctttgatctc ttccgggtca aaagacatcg ccgatatatt gaaggcattt
    32521 cgatgaacca atcgatcagg atctgcattc atgagtttta taatggcatc gatcgcatct
    32581 ggcatataca tcatatccat tgatgtacct tgatcaatga aactagtgta ctttccttct
    32641 ttgattgctg aataataaat atcgactgcg tagtctgtcg taccgcctcc tggcaaggtt
    32701 gcataagaaa tcaatccagg gaaacggaca ccacgagtat ctacgccata tttcacataa
    32761 taataatcac atagtagttc tccagctacc ttcgttaccc catacatggt tgtaggacgc
    32821 tgaagagtat cttgtggggt atgatctttt ggagtatttg gaccaaacgc gccgattgaa
    32881 cttggcgtaa aaaatttcag ctggaattct ctagcgactt ccaatgcatt gaccagccca
    32941 gtcacgttca aattccaggc taattgtggt tttgcttctg caacagctga caaaagagca
    33001 gccaaatgaa tcaatgtgtc cacttgatat tgttctgcta tgctgcgcat tttttcgtaa
    33061 tccattacat ctaggatctc aaagatatcg tttttctcaa tgacttcagg catgcgtata
    33121 tctgtcgcaa tgacattttc actgcctagt tcttgacgta gccgtgtgat caactctgaa
    33181 ccaatttgtc ctaaacatcc tgtcaccaat acttttttca tgatgatcct ccctgatctt
    33241 ttttactact atcttcagat gattaacaat atatgcgtga acatgttctc taattttaaa
    33301 tagacgaaaa aactaaattt agttaaataa tttccatttc ttttcctatt ttttgataaa
    33361 ctgctactgc ttcatcaagc atttccctcg tatgttccgc agtcggcata tttctgatcc
    33421 tgcctgtccc aagaggcaca gttggataaa cgattggttt agcataaatc ccatgttcga
    33481 tcagcttctt agagaaagtc tgagtcactt tttcgtctcc caaaatgact ggagtaatag
    33541 gtgtttcaga cataccgatg ttatagccta cttttttcaa ttcttcttta aaataattag
    33601 cattttccca aactttttcg acaagttccg gatgttcttg catcaaagta atcgaagcca
    33661 atgcagctgc agctgcacct ggagttagcg aagtagaaaa taggaatggc cgacttctag
    33721 ctttcaacca gtcgattagt gttttcgatc cagctacata acccccaaca acacctatag
    33781 ctttcgataa cgtgcccatt tgcatatcga ttttgtcgct taatccaaaa tgcttgacgg
    33841 ttcctgcacc ttttccagtt acgcctgagc cgtgcgcatc atcgacgtag gtgatcagtc
    33901 catatttttc aacaatcgga ataatttccg gcaatcgtgc aatgtctcca tccatggaga
    33961 aaacaccatc tgtgatatac atgatttttt tatatttctt actttctatc gcttcctttg
    34021 cttttttctc aaggtctttc atatcttgat gtttaattcg gatgattttt gctccggata
    34081 agcggcaacc gtcaataata gatgcatggt ttaattcatc cgataagata gcatcttctt
    34141 ttgtcattac tgcagagata gcgcccatat tgcagttgaa tccagattga aaggcgattg
    34201 ctgcttctgt ccctttgaat tctgcgattt tttcttctaa ttgctgatgg attttcagcg
    34261 aaccattgat cgttcggact gctcctgctc ctacaccata agtttcggtt gcttcaatac
    34321 atgctttttt caattcttcg cgattggcaa atccaagata attgttggat gctagattga
    34381 tcatcttttt tccgtctacg atgatacaag caccattttc actttctagt atgtcgatcg
    34441 tattgtataa ccccttttct ttcagttgat ccaattcttt ctctaaatac attgttagtt
    34501 ctttggaaga cattgtctcc acctccatat tcatctgtct tgcagaacat accaaacata
    34561 tatcgtgtca ttcatctaca aagcaagtat gctatatttt tgataacgct tacactgatt
    34621 atgagaatta tttaaccaca ttttttattt acagtatctt tttactttca aatgacttat
    34681 atagtatgaa caattacctt ttagataatg atctatttta ctctacctgg gcagataaat
    34741 acaacacaac cattgataga agccctttcg ttaaaatcaa ttgtattctg aatatttaat
    34801 ttatttattg catagaccaa taaaaataca taaaatttcc atcttcgttt atcagcaatt
    34861 tttaatttta ctctctgaat atttcttaaa agttttactt gttgaattcg aaaaaaggac
    34921 tgtgacaaaa gtcttgtcac agtcctattc ttccgaata
//
LOCUS       DBBGSZ010000027        34687 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.027, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000027 DBBGSZ010000000
VERSION     DBBGSZ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34687
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.027"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            591..1280
                     /locus_tag="ACIZE5_001791"
     CDS             591..1280
                     /locus_tag="ACIZE5_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGC6108918.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="ACIZE5_001792"
     CDS             1267..2475
                     /locus_tag="ACIZE5_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGC6108919.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="ACIZE5_001793"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="ACIZE5_001793"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HGC6108920.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="ACIZE5_001794"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="ACIZE5_001794"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HGC6108921.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="ACIZE5_001795"
     CDS             complement(6578..7273)
                     /locus_tag="ACIZE5_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HGC6108922.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="ACIZE5_001796"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="ACIZE5_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HGC6108923.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="ACIZE5_001797"
     CDS             complement(8472..8663)
                     /locus_tag="ACIZE5_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HGC6108924.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="ACIZE5_001798"
     CDS             complement(8684..9574)
                     /locus_tag="ACIZE5_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HGC6108925.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="ACIZE5_001799"
     CDS             complement(9561..10328)
                     /locus_tag="ACIZE5_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HGC6108926.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="ACIZE5_001800"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="ACIZE5_001800"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HGC6108927.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="ACIZE5_001801"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="ACIZE5_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HGC6108928.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="ACIZE5_001802"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="ACIZE5_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HGC6108929.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14899..15282
                     /locus_tag="ACIZE5_001803"
     CDS             14899..15282
                     /locus_tag="ACIZE5_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108930.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15450..16208)
                     /gene="jag"
                     /locus_tag="ACIZE5_001804"
     CDS             complement(15450..16208)
                     /gene="jag"
                     /locus_tag="ACIZE5_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HGC6108931.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="ACIZE5_001805"
     CDS             complement(16226..17044)
                     /locus_tag="ACIZE5_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HGC6108932.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="ACIZE5_001806"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="ACIZE5_001806"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HGC6108933.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="ACIZE5_001807"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="ACIZE5_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HGC6108934.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18172..19506
                     /gene="dnaA"
                     /locus_tag="ACIZE5_001808"
     CDS             18172..19506
                     /gene="dnaA"
                     /locus_tag="ACIZE5_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HGC6108935.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19704..20834
                     /gene="dnaN"
                     /locus_tag="ACIZE5_001809"
     CDS             19704..20834
                     /gene="dnaN"
                     /locus_tag="ACIZE5_001809"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HGC6108936.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21063..21305
                     /gene="yaaA"
                     /locus_tag="ACIZE5_001810"
     CDS             21063..21305
                     /gene="yaaA"
                     /locus_tag="ACIZE5_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HGC6108937.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21292..22416
                     /gene="recF"
                     /locus_tag="ACIZE5_001811"
     CDS             21292..22416
                     /gene="recF"
                     /locus_tag="ACIZE5_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HGC6108938.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22413..24359
                     /gene="gyrB"
                     /locus_tag="ACIZE5_001812"
     CDS             22413..24359
                     /gene="gyrB"
                     /locus_tag="ACIZE5_001812"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HGC6108939.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24379..26850
                     /gene="gyrA"
                     /locus_tag="ACIZE5_001813"
     CDS             24379..26850
                     /gene="gyrA"
                     /locus_tag="ACIZE5_001813"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HGC6108940.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27086..27385
                     /gene="rpsF"
                     /locus_tag="ACIZE5_001814"
     CDS             27086..27385
                     /gene="rpsF"
                     /locus_tag="ACIZE5_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HGC6108941.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27435..27947
                     /gene="ssb"
                     /locus_tag="ACIZE5_001815"
     CDS             27435..27947
                     /gene="ssb"
                     /locus_tag="ACIZE5_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGC6108942.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27973..28209
                     /gene="rpsR"
                     /locus_tag="ACIZE5_001816"
     CDS             27973..28209
                     /gene="rpsR"
                     /locus_tag="ACIZE5_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HGC6108943.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28352..30325
                     /locus_tag="ACIZE5_001817"
     CDS             28352..30325
                     /locus_tag="ACIZE5_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HGC6108944.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30331..30783
                     /gene="rplI"
                     /locus_tag="ACIZE5_001818"
     CDS             30331..30783
                     /gene="rplI"
                     /locus_tag="ACIZE5_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HGC6108945.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31057..32424
                     /gene="dnaB"
                     /locus_tag="ACIZE5_001819"
     CDS             31057..32424
                     /gene="dnaB"
                     /locus_tag="ACIZE5_001819"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HGC6108946.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33204..34496
                     /locus_tag="ACIZE5_001820"
     CDS             33204..34496
                     /locus_tag="ACIZE5_001820"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HGC6108947.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10569 a         6743 c         6858 g        10517 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgtggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gaatcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa aggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggcgatttc ctgtgtattc cgtctcctaa ctattggtat atctgtattt
    17941 tttatccaca gacgcaagag gaaatctatt ggtttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt tgacaactgt gtttttctct tttttctttt tgtcgattgt
    18061 gtggataatt gtaattaaaa aatttttttc ttcggtttct gtggaaaact attgaaaaaa
    18121 atgctaaatt agtactagtt attcactttt taatgaagga ggaggcctta tatggtatcc
    18181 ctcgatgctt tatggaatga attaaaagca acataccaaa aggatttatc gcctgctagc
    18241 tataatacat ggatcgaaac agcgaaccct cgaacccttg atcaaaacca gctcgttgtt
    18301 gaggttccta gcaagattca taaagaatat tgggaaaaaa acctggcgac aaaaatcgtt
    18361 gaagtcggtt atatgttatc aggaaatgag attatccctc gctttattac tggcgaagaa
    18421 gcagagcaag aagaagttat agaagaaaaa aatccaaaag ttgtggcacc tagtccgcta
    18481 aaaaaagcca tgctgaaccc taaatatacc tttgatacgt ttgtcattgg taaaggaaac
    18541 cagatggctc atgcagcagc gctcgttgta gcagaagatc caggttctat ttataacccg
    18601 ctcttctttt atggaggcgt gggacttggt aagactcact tgatgcatgc aattggtcat
    18661 caaatgctgc aaagtcagcc taatgccaaa gtaaaatatg taagcagtga aacttttgct
    18721 aatgatttca tcaattcgat ccaaaacaaa acagcagaag agttccgtca agaatatcga
    18781 aatgttgatt tactgctagt ggatgacatt caattttttg cagaaaaaga agctacgcaa
    18841 gaagagtttt tccatacttt caatgccttg tacaatgaag ggaaacaaat cgtactaacc
    18901 agtgatcggt tgccaaacga gattccgaaa ctgcaagaac gccttgtttc tcgctttgca
    18961 tgggggctgt ctgttgatat tacaccgccg gatcttgaaa caagaacagc gattttacgt
    19021 aaaaaagcgg cggctgaacg tctagagatc ccagatgaca cactaagcta catcgcagga
    19081 caaattgatt ctaacattcg tgaattagaa ggtgcgcttg ttcgagtgca agcttttgct
    19141 gcgatgaata gtgaagatat ttcgactagt ctagctgcag acgcactgaa aacgttaaaa
    19201 tcaggaaaag gacatcctca attgtcaatc ctgcagatcc aagaagaagt ggcaaagtat
    19261 tatcacatcc aattgaaaga tctcaaagga aagaaacgcg tcaaatctat tgttgttcct
    19321 agacaaatcg ctatgtattt ggcacgtgag ctcacagata attctttacc gaaaatcgga
    19381 gctgaattcg gtggcaagga tcatacaacg gttatccatg ctcatgaaaa aatccagcag
    19441 ctgatggatt ctagtgtcag tatgcaaaat gaagtatcag aaatcaaaaa ctttttacta
    19501 aattaatttg tcgattctat caactgaaaa tagcatgtgg ataaaagaaa aaaacgttca
    19561 aaagttatac acactttttc cacagctgtt ttttcgtttc tctcttacgt tttttgagtt
    19621 ttccacagaa tcaacatgcc ctattacttt tattattctt tttaactaat aataaataaa
    19681 caaacattca aaggagatac atcatgaaag ttactttaaa ccgagctagc tttatgcagg
    19741 aattgcaaac tgttcaacga gctatttcaa gcaaaaccac gatccctatt ttgacaggtg
    19801 taaaaatcac actgacacaa gaaggtttga ctttgacggg gagcaacgct gatatatcaa
    19861 ttgaaacttt tttgtctgtt gaaaacgaaa aagcaaatat gcaaatcgaa tctactggtt
    19921 ccattgtttt acaagcacgt ttctttagcg aaatcattcg gagacttcct gaagaaacat
    19981 ttactttaga agttttagaa aataaacaag tagcgatcac ttctggaaaa gcgaatttta
    20041 tcgtaaatgg attagatgca gataactatc ctcatcttcc tgttgtcgaa agccataacc
    20101 agatgaaatt acctgtacac gtattgacta aactaatcaa cgaaacagtt tttgctgtct
    20161 cacaacatga gagtcgtcca atcttgacag gtgtgcattt cattttatct gataattctt
    20221 tattagctgt agctactgat tctcaccgtc taagtcaacg cgtgattcca gtagaacaag
    20281 cggctgatca ttttgatatt gttattcctg gaaaaagttt gatcgaatta tctcgctcat
    20341 taacaaatga agaagaaatc gtcgaaatca gcattatgga aaaccaagtg ttgttcaaaa
    20401 cagaaacgat gtatttctat tcccgtttgc tagaaggaaa ctatccagat accaatcgtt
    20461 tgattccttc aagttttaat acagaggttg aattttctgt tcctagcttt ttagcggcga
    20521 tcgaacgggc ttctttactt tctcatgaag gccgtaacaa catcgttcgt ttatctattc
    20581 gtccagatgc ggttgtttta tacggaaatt cgccagaaat cgggaaagta gaagaaagct
    20641 tgagttatac agcaagcagt ggcgatccat tagatatttc tttcaatccg gattatatga
    20701 aagcagcgtt gcgtgcattt ggagatatga gcatcaaagt gaaatttatc tctgctattc
    20761 gtccatttac attggaacca acggaagatg gcgttcaatt tattcagctg attactcctg
    20821 tacgtacaaa ttaacaatga ttttcaatgt tcttgaaaat ttaattgaaa agaaatagaa
    20881 aaaataaaat tttaaacaga aggccctaaa atctctttta aggctttctg tttatttttg
    20941 tttaaatcac cttttttaga ttaaatcgtc ttatatggaa aaatatatgg ataaatttgt
    21001 tttattgcga aaaaaaaggt ataatagagt atacttttaa taatgaaaat gagggatggg
    21061 cattgaaaca acaagtcatt ctaaatacgg aattcatgac gttgggccaa atgttgaaag
    21121 aagtcacagt tatcggtagt ggcggacaag caaaatggta tttggcagaa aacactgtgt
    21181 tagtcgatgg cgaaccagaa aatcgtcgtg gacgcaaact ttatcccggc atgatggttg
    21241 aagttccaga agtaggaact ttttttatgg taaaaaaagg aaacgacgat aatgaggctg
    21301 aataagctgt atttaaaaaa ttatcgaaat tacgaagagc tgaacatcga attttccaag
    21361 aacctcgtca tctttttagg agaaaatgcg caaggaaaaa cgaatctttt ggaaagtatc
    21421 tacgtattag ctatgacgcg aagtcatcgg acaagtagtg agcaggaatt gattggctgg
    21481 actgacgatc aggcgatgat tcaaggagag atcacaaaag gttcatccac tcttccatta
    21541 gaaatcttat tatctaaaaa aggccgaaaa accaagatca accatatcga acagaaaaag
    21601 ttaagtactt acgtgggaca aatgaatgtc attttatttg caccagaaga tctttcttta
    21661 gtaaaaggca gcccgcagat caggcggaag tttttagata tggaattagg ccagatcaat
    21721 ccaatctatc tttatgatct tgtccaatac caagcaattt tgaaacaaag aaaccagtac
    21781 ttgaagcaat tgaatgaaaa aaaacaaact gatttgcttt atttggatat tttgtccgaa
    21841 caactagcag cgtttggcag caaagtattg aaagcaagag cacagttcgt caagcgattg
    21901 gagttttggg ctaattcttt gcatcagcaa atcacccatc aaaaagagca gctggaaatc
    21961 gagtatctca ccgcagtcga ttctttagaa acacatacgc aagagcaaat ccaagaacaa
    22021 tttctcgcac ttttgaacca aaataaaaag aaagaccttt ttcggggaac aacgacagtt
    22081 ggtcctcatc gtgacgatct ttcctttttt attaatcaga aaaatgtgca gacttatgga
    22141 tcgcaaggac agcaaagaac aactgcacta agtgtcaaat tagcagaaat cgatttgatt
    22201 aaagaagaga caggggaata tccaatcctt ttgttagatg atgtgatgag cgagctggat
    22261 gataatcgtc aactccatct gctagaaaca atcgaaggaa aagttcaaac gttcttaaca
    22321 acaacgacac ttgaccatgt aaaaaataaa atgactgttg aacctgagat tttttatgtt
    22381 caacaaggga aactaaaagg agaagaaact gaatgacaga agaaagaagt ttagtagaac
    22441 gcgctaaaga gtatgatgcc agtcagattc aagtacttga aggacttgaa gccgttcgta
    22501 aacgacctgg catgtatatc ggttcgacta gttctgaggg tctgcatcac cttgtttggg
    22561 aaattgtcga taattcgatc gatgaagtat tagcaggttt tgcaacgaaa atccatgtga
    22621 ttattgaaaa agacaacagt atcaccgtta ttgacgacgg tcgggggata cctgtagata
    22681 tccaggcaaa aactggacgt cctgcagttg aaacggtctt tactgtttta catgctggag
    22741 gaaaattcgg cggtggtggg tacaaagttt ctggtggact tcacggagta ggatcttctg
    22801 ttgtaaacgc gctttctaca cagcttgatg tcaaagtata caaagaagga aatgtgtact
    22861 atcaagaata tcgtcgtgga gctgtagtgg acgacttaaa gattatcgaa caaacggatc
    22921 gccatggaac aacggttcac tttacgccag accctgaaat ttttacagag acaactgagt
    22981 ttgatttttc aaaattggct acccggatcc gtgaacttgc tttcttgaac cgcgggatgc
    23041 gtatatcgat tgaagacaaa cgagaagaag aaccagtcat caatgaatac cattatgacg
    23101 gcgggatcaa aagttatgtc gaatacttga atgcaaacaa aaccgtgatt tttccagaac
    23161 ctgtatattt ggaaggtgaa cagcaagata tcgcagttga agtctctatg caatatacag
    23221 acggctacca ttccaatatc atgagttttg ccaacaatat ccatacgtat gaaggtggaa
    23281 cacatgaatc aggattcaag actgctttaa ctcgtgtgat aaatgattat gcccgaaaac
    23341 aaaagctgat gaaagaaaat gacgacaact tgaccggtga agacgtgcga gaaggattga
    23401 cagctgttat ttctatcaag catcctgacc ctcaattcga aggacaaaca aaaacaaaat
    23461 tgggcaattc cgaagtacgg acagtcactg atcggttatt tagcgaacat ttcatgaaat
    23521 tcttgctgga aaacccaagt gtgggccggc aaattgttga aaaaggatta ctagcttcca
    23581 gagctcgtct agcagcgaaa cgtgcgcgtg aagtaacgag acgtaaaggt gctttagaga
    23641 ttagtaatct gccaggaaaa ttagcggact gctctagcaa cgatcctgaa aaatgcgaat
    23701 tgttcatcgt cgaaggagat tcggccggcg gatcagctaa gcaaggtcgt aatcgagagt
    23761 ttcaagccat cttgcctatt cgtgggaaaa tcttgaatgt tgaaaaagca agcatggaca
    23821 agatcttggc aaatgaagag atccggtctt tatttactgc tatgggtaca gggtttggag
    23881 aagattttga tgtatcgaaa gctcgctacc acaaattagt tatcatgact gatgccgatg
    23941 tcgacggcgc gcatatccgt acattgctgc tgactctttt ttatcgttac atgcgtccta
    24001 ttgttgaagc tggatacgtc tatattgctc agccaccttt atacggggta aaacaaggga
    24061 agaatattac gtatgtacaa ccaggaaaaa atgcagaaga agagttgaaa caagtcgttg
    24121 cttcacttcc tgcctcacca aaaccaagcg ttcagcgtta taaaggactt ggagaaatgg
    24181 atgatcatca actatgggaa acaactatgg acccaagcaa tcggatgatg gcccgcgtca
    24241 gtgtggacga tgctattgca gcagatcaga tatttgaaat gttgatgggg gatcgagtag
    24301 aaccccgtcg tgcattcatc gaggaaaatg cacactatgt gaagaactta gatatttaat
    24361 catgaaggag gaaaaagaat gagtgaagaa atcagagaaa acatccatga tgtcaatcta
    24421 accagcgaaa tgaaagactc cttcatcgat tatgcgatga gtgttattgt cgcacgtgca
    24481 cttcctgatg tcagagatgg tctgaaaccc gttcatcgcc gtattttata cggcatgaac
    24541 gaattaggtg taacaccgga taaagcccat aaaaaatctg ccagaatcgt cggagatgtc
    24601 atgggtaaat accatcctca tggagacatt gcgatctatg agtcaatggt acggatggca
    24661 cagccattca gctaccgtta tatgctagtg gatggtcatg gaaactttgg ttctgttgac
    24721 ggtgacggtg ccgccgctat gcgttatacc gaagcacgga tgagcaaaat cgctacagaa
    24781 atgctgcgtg atatcaataa gaacactgtt gatttccaaa gcaactatga tgatacagaa
    24841 aaagaaccag ttgtactacc tgctcgcttc ccgaatcttt tagtgaacgg aacaacgggg
    24901 atcgccgtag gtatggccac gaatatccca cctcataact tgtctgaggt agtagcggct
    24961 atcgatttgc tgatggataa tcctgatgtg acgaccaatg aattgatgga agtattacct
    25021 ggaccagatt ttccaacagg tggtttggtt atggggaaat caggaatccg aagagcgtat
    25081 gaaacaggta agggttctat taccgtacgt gcaaaagttg agattactga gatgccaaat
    25141 ggtaaagaac ggatcatcgt gacagaattg ccttatatgg tcaataaagc aaaattgatc
    25201 gaacggattt ctgaactgca cagagacaag cgtatcgaag ggatcacaga tttgcgggac
    25261 gaatcttccc gtgaaggtat gcggatcgtc attgacatcc gtcgtgacgc cagcgcatcc
    25321 gttatcttga ataacttata taaattgaca tccttgcaaa attcatttgg attcaatatg
    25381 ttggcgatcg aaaaaggtgt gccgaaagtt ttgagcttga aacaaatcct tgaaaactat
    25441 atcgaacatc aacgcgaagt catcacacga cggacggtct ttgaaaaaga aaaagcagaa
    25501 gcaagagcac acatcttaga aggtttgcgt attgctttgg atcatatcga tgaaatcatt
    25561 gcgattatcc gcgggtctaa atcagatgac gaggcaaaag caacaatgat cgaacggttc
    25621 gatttatccg atcgccagtc tcaagctatt ttagatatgc gtttacgccg attgaccggt
    25681 ttggaacggg aaaaaatcga aaatgaatac caagaactct taaaactgat tgaagattta
    25741 actgacattc tggcaagacc agaacgtgtt acagaaatca tcaagaatga attagcagac
    25801 ttgaatcaac gatttggtga taaacgacgc acagaattac tagtcggtga ggtcttaagt
    25861 ctggaagatg aagatttaat cgaagaagaa gaaatcgtta ttacattgac aaacaatggt
    25921 tacatcaaac gtttggcaaa taatgaattc agagctcaac gaaggggtgg acgtggtgtc
    25981 caaggaatgg gtatccacaa tgacgacttc gtcaaaaatc tggtttcttg ttctacccat
    26041 gatacattgt tattctttac gaataacgga aaagtgtatc gggcaaaagg atacgaaatt
    26101 ccagaatacg ggcgtacagc caaaggaatc ccaatcatca atttactagg tatcgattcg
    26161 agtgaaagca tccaggcaat cattgcggtg acgggagaag cagaagaagg ccactatctc
    26221 ttctttacga cgcgtcaagg tacagtaaaa cgtacttctg tcactgcttt tgctaacatc
    26281 cgaagtaatg gtctgatcgc aattggtttg aaagaagacg atgagctcgt caatgtgcta
    26341 ctgacagatg gtcaatctaa tatcattatt ggaacacata acggctactc tgtcactttc
    26401 aaagaagaag cagtccgcga tatgggacgt acagcttccg gggtcagagg gatacgcctg
    26461 cgtgaggaag attatgtcgt tggggcagcc ttaatgaagg aaaatcaaga agtattagtg
    26521 atcacagaaa aaggttacgg aaaacggaca aaagtatcgg aatatccagt gaaaggccgc
    26581 ggaggtaaag ggatcaaaac ggcgaacatc actgaaaaaa atggtccact agctggattg
    26641 accactgttt ctggagatga agacatcatg ctgattacag ataaaggtgt cattatccgt
    26701 ttcaacgtat cgactgtttc tcaaactgga cgttcaacat taggcgtacg tttgatgaag
    26761 atggaagctg atacgaaagt tgtcacgatg gcagcagtcg aaccagaagc tgcagaacaa
    26821 acagttgaag aacaaggatc agaagaataa ccatcaagac taagtgtgta agctagcaag
    26881 aataaccgat taaaaaatct ggttattcct gctggctttt ttgattagtt gaatttctct
    26941 taaaatattc gaaactgttc attctgtatt gcttttgacc aaaatagagt gtataattag
    27001 agcttgtgag tagtctaatt aattagataa ctctccttgc tcttaggaac ctaagagccg
    27061 aaagtccaca gggaggtgaa tatcaatgga aaacacgaaa tatgaaatca tgtacattat
    27121 tcgtccaaac attgatgaag aagcaaaaac tgctttaatc gaacgtttcg atgcaatctt
    27181 gaaagataac ggagcagaag ttatcgaatc aaaagattgg gaaaaacgcc gtttcgctta
    27241 tgaaatgaac ggttaccgtg aaggtatcta tcacatcgtt aaagtatctt ctccatcatc
    27301 agcaaatgct gtcaatgaat ttgaccgtct tgctaaaatc aacgacgata tcattcgtca
    27361 catgattgtt aaagaagaag cttaattgtt gtttcatgtg aaacaataga aaacgatgag
    27421 aggagatgac tattttgatt aataatgttg tattagttgg acgtctgacg aaagatccag
    27481 atttgcgtta cacagcaagt ggtacggcag tcgcaacatt tactttggct gtgaatcgta
    27541 attttacaaa ccaaagcggc aatcgcgagg ctgattttat caactgtgtg atttggcgca
    27601 aatcagcaga aactttagca aactatgctc gtaaaggaac acttttaggt gttactggac
    27661 gtatccaaac tcgttcttat gataatcagc aaggacaacg tgtatacgtg acagaagtag
    27721 tagctgacaa cttccaattg ctggaaagtc gttctgcatc tgaaaatcgc caacaaagcg
    27781 gcggattcca aagttctggt caatcagctg gcggatttgg cggaaacaat aactctaatc
    27841 aaacatctca atcatccaac ggtatgcctg atttcgaccg tgatacttct gacccattcg
    27901 gctcaagttc aacgatcgac atttcagacg atgatttacc attctaaacg aatttgatag
    27961 gagggaaata gaatggcaca acaaagaaga ggcggacgta aacgtcgtaa agtagactac
    28021 attgctgcta accatattga atatatcgat tataaagata tcgaattact aaaaagattt
    28081 atttcagaac gcggtaaaat cttgccacgt cgtgtaactg gtacaggcgc taaaaaccaa
    28141 cgtaaaatta ctgttgcaat caaacgcgct cgtatcatgg gcttgctacc tttcgttagc
    28201 gaagactaat aaatcctagg aattgaatga ctgatccttt tgatcagcta ttcaattcct
    28261 ttttttctgt aaaaataacc tctattcgtt tagtcgctcg aatgacgaaa gttatggtaa
    28321 aatcaaatta gtcatatatg ggaggaaaat tatggaaaat aaaaacaatc atttatcccc
    28381 gaaacctctc ttccttatcc tgtttatatt aatcgaagta ttggtagtct taattttacc
    28441 atttcgtttt gttagcgctt cggtcattct attgatgaat ttatggggtg ttcgctattg
    28501 gttgaaaatg aaacgttggc ttattttaaa taaacgtgaa aaaatccagc aggcttcgac
    28561 tgtagctgaa accaatctag cttatgtctc agaagtcatg cctgtaggag tgattgctta
    28621 tcagccatca agccaaaaaa tcgaatggct caatccatta gcattgaaaa tcaaagatca
    28681 aagtggatta acagaggaag aattgctaga tacttttttt actgcaaaag aaaaaaagaa
    28741 aaaccaagtc tatctagcag ataaaacatt tcagtttgat atggatacag taaagggtgt
    28801 tgtttatttt aatgatatta cccaaaacca gttgttaaaa ctccatcaga cgaacagtca
    28861 gccggtgatt ggtattttat ctattgataa ctatgcagat gccattgata aattagatga
    28921 caaagagatt tcttatttga actctttcgt cactacacta gtttctgact ggatgaatga
    28981 ataccatgtc tttttcaaaa gaatcaacgc agaacggttt ttcttcgtag cacagatgat
    29041 cgatctgaaa aagatgatgg ataaaaaatt tgatttgctg gatcgctttc gagcagaagc
    29101 tgaaaaacag agctcgccta tcacccttag tatggggatt gcttatggct caagaaccct
    29161 cgatgaaatc ggtggagaag ctcagaataa tttagatgtt gctttagtcc gtggaggcga
    29221 ccaagttgtc gtgaaagagg taaaagaagg agcaaaacct gtttattatg gggggaaatc
    29281 tgctaagaat gtcaaacgca cgcgtgttcg ttctcgagcg atgagtaccg ctttgcgtcg
    29341 gatttttgat gaaacaggcg atgtgtttat catggggcac aagtttccgg atatggatgc
    29401 tttaggctct gcttttggtg tcagttgtct ggcacgcttc aaccagaaaa aagcttacat
    29461 cgttatcaat gagaacgaga tcattccaga tgtagaacgg tgtcttgaag aaatccataa
    29521 gcatcctgaa ttagaaatgc aactaatctc tccagaacgt gccatagagc tgaaaaaaga
    29581 agaggacctc ctcgtgatgg tggattacca taaaccttct ctatcgatct ctcagggcct
    29641 atatgagcaa tttgataaga ttgtgatcat tgatcaccat cgtcgtgggg aagagtttcc
    29701 aagtaaacct ctgctgactt atattgaatc ttcagcttct tcagcttcag agctagtttc
    29761 tgagctgatc caataccaaa gcagcaaaac aaatcgctta gatcgttttg aggccacatt
    29821 attgcttgca gggatggttg tagatacaaa tagtttcaat gtccgtacaa ctgcacgaac
    29881 ttttgacgtt gccagctatt taaggtcttg tggagcagac gcatccttag tacaatattt
    29941 attgagctcg gatttagcga catacttgga gatcagcaat ttgattgctg gaagcgacta
    30001 tgtgacttct gatattgttg tggcggcagg gacagacgaa aaagagtata atagtgttat
    30061 agcagcaaaa acagcagata cattgctttc gatgatcaat atcaatgcag ctttcgtcat
    30121 tacaaagcgg acagacggct tgattgggat cagtgccaga agtaccggca cgatcaacgt
    30181 ccaaatcatc atggaatcct taggtggcgg aggacacttc acaaacgcag ctactcaact
    30241 ggaaaatacg acagttgagg aaacaaaaca gaagctattt gctgcaatca aagaaaatat
    30301 gaatcaaata tatgataagg agtaatccaa atgaaagtaa tttttttaca agatgtaaaa
    30361 ggaaaaggta aaaaagggga catcaaagaa gttccagcag gttatgcaca aaattatcta
    30421 atcaaaaata acttggcaaa agaagcaacg aaaagcagta tcagtcagtt agcaggacaa
    30481 aagaaagcac aagaaaaaca cgaagctgaa atcttggaag aagctaaaaa gttaaaagaa
    30541 ttcttggaaa aagaagatac tgtagtcgaa ttgaaggcga aagcagggga agacagccgt
    30601 ttgtttggtt cgatcccttc aaaacaaatt gctgaagggt taaacaaaca atacaaaatc
    30661 aaattagata aacgaaaaat cgaattagaa aatccgatcc gttcactagg ctacacaaac
    30721 gtacctgtta agcttcatca tgaggtgacg gctacgatca aagttcatgt cgtacaagaa
    30781 taacaaatct tgatagcgat gttcagctgg taagtataac cagaaggaaa aaagacaaac
    30841 cgaaatttat ctgagaaaac agctgcagca atgaaagcaa aagctgcaaa tcgatttcag
    30901 attgatttcg gtttcttttt tgggaacagc aaaatagcat aaagaaaacg agtataataa
    30961 aagagaacta tttttttatt acactttcgg tacgaatgat gacttttctc tcattttctt
    31021 gtaaaatgaa gcaattgaag acaaggagcg atacgtatga atgaagtgtg gcaggatcga
    31081 atcccaccgc aaaatattga agctgaacaa gcggttttag gctctgtttt tcttgacgca
    31141 gaaacgatca ttgatgccat ggagtacata gagccaaaag acttttatcg tcgtggccat
    31201 caaattattt ttgagacaat gatcgagtta aatgatcgta atgaagcgat tgacgtggtt
    31261 actgtcaaag accggctgga acaagccaat ttgttagaag atgccggtgg tttaagttat
    31321 ctctcagact tggcattagc agttccgaca gcagcaaata tcgtctacta tgcgaaaatc
    31381 gttgaagaaa aatcattgct gcgtacattg atccagacag caacaggaat cgttacgaaa
    31441 ggattcgagc aaggagaaga agttcaaaca attttagatg atgccgaacg cagtatcttg
    31501 gaggtttcgg aaaaaagaaa tcgaagcggc tttttatcta ttgctgaagt actgaactcc
    31561 acgattgaaa atatcgatcg actagctcaa aacaatgaag aaatcacagg tctaccaact
    31621 ggctatcaag gtctggataa aatgacagca ggtttccagc ccgaagaact aatcattctt
    31681 gctgcacgtc cagcggtagg taaaacagcg tttgcattga atattgctca aaatgtagga
    31741 acaaaaacag atcgttctgt tgcgatattt agtttggaaa tgggggcaga atctcttgta
    31801 aatcggatgc tttgtgcaga aggttcgatt gaggccagcc atttacgtac aggtcagctt
    31861 tcggaagaag aatggtcgaa tctgatcgtt gcgatgggga gtctttctcg agcaaatatt
    31921 tttatcgatg atacaccagg gatcaaaatc tctgaaatcc gtgcgaaatg tcggaaacta
    31981 gcgcaagaaa aaggcaatct aggcttgata ttgatcgatt atttgcagtt gattgaaggt
    32041 aacggtaaag agaaccgtca acaagaagta tcagatatct ctcgccaact gaaaaaactg
    32101 gcgaaagagc tgaaagtacc tgtcattgct ctttcacagt tatctcgtgg agtagaacag
    32161 cgacaagaca aacgaccagt gctaagtgat attcgtgaat ccggatcaat tgaacaagat
    32221 gcggacatcg tagccttctt gtatcgagat gattattatg aaagagaagg cggagatgac
    32281 gatgatggaa acgagccaaa aaatgacaac gtcatcgaag tcatcatcga gaagaaccga
    32341 agcggtgcac gaggaacagt tgaactactg tttatcaaag aatacaataa gttttcgtcg
    32401 ctttcgccaa gagaagaatt ttaaagaaga ggttgtgagc cttgagcaat cccgagagct
    32461 ctcgtaagaa gatgcaagga gtaaccgcag gaacgactag agtacttaat ttaaacagat
    32521 ctccaaaggg attgtgacaa aagtcttgtc acagtccctt tttccgaata aacggtgttc
    32581 aatcagctga cccttggtat tagctcagca aacgtcaaaa tatgaggaac tattttgacg
    32641 tttgtttctc taatactcag gtcaaaacgc tgatcttacg acctcttttc cttaaacggt
    32701 gttctcctgc caactcctcg gtcacaagtc acaatatcat caaacatgag aagcagtttt
    32761 ttgaaattgc tccttgtgac tcagagttaa acggcaggct cacaacctct ttcttaaacg
    32821 gtgttcaaaa gcttgcatct gcggtaatac gcccaatcaa acgaaaaata tgagaagcta
    32881 tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca
    32941 cggtgttcca aaagtagctt cttcgaaaaa taagtcgaaa tttcacaaaa atttgagaag
    33001 caattttcgt acattccttc ttatttcttg aagctgacca cttctgttac aacctctttt
    33061 ttaataacca ttctaaaaag ataaagttcg ttttttaagc gtttttataa aataaaaata
    33121 aaaatcattc gattttattt gaaatatgta tctattattg atacaatggt tcaggattaa
    33181 ataatataga acgaggtgtt cacatgtcat ctgtagtagt agtaggtacg caatggggcg
    33241 atgaagggaa aggaaaaatc acagactttc tcagtgaaaa tgctgaagtg attgcacggt
    33301 accaaggtgg cgacaatgca gggcacacaa ttaagtttaa cggtgtgact tataaactgc
    33361 atttgattcc ttctgggatt ttttataaag acaagatcag tgtgatcgga aacggcgttg
    33421 tagtcaatcc taaatcattg gttaaagaat tagcttattt acatgaaaaa ggtgtagaaa
    33481 caagtaattt gcgtatttct gaccgcgcgc acgtaatctt gccttatcat atcaaattgg
    33541 accaattaca agaagatgct aagggcgaaa ataagattgg tacaacgatt aaaggaatcg
    33601 gacctgccta tatggataaa gcagctcgtg taggtatccg tattgcagac ttattagata
    33661 aagaaatttt tgaagaacgt cttcgtttga atctagatga caaaaaccgt caatttgtaa
    33721 aaatgtttga ttcagaacca cttgattttg acgatatttt tgaagaatat tatgaatacg
    33781 gacaacaaat caaacaatac gtcacagata cttccgttat cttgaatgat gctttggatg
    33841 caggcaaacg cgtgttgttt gaaggcgcac aaggtgtaat gctggatatc gaccagggaa
    33901 cttatccttt tgttacttct tctaacccag tagccggtgg ggtaacaatc ggaagcggtg
    33961 tagggccttc aaaaatcaat aaagttgtcg gcgtctgcaa agcctatacg tcacgtgtcg
    34021 gtgatggacc atttccaact gaattatttg atgaaacagg agaacaaatc cgcgaagtag
    34081 gacgagaata cggtacgaca actggtcgtc cgcgtcgtgt aggctggttt gattctgtag
    34141 ttatgcgcca ttctaaacga gtttcaggta ttaccaacct atctttaaac tcgatcgatg
    34201 tattaagtgg attggaaaca gtaaaaattt gtacggctta tgaattagat ggcgaactaa
    34261 tctaccacta tccagcaagc ttgaaagagt tgaaccgctg caaaccaatc tatgaagaat
    34321 tgccaggctg gtcagaagac attacaggat gcaaaacact tgcagaactg ccagaaaacg
    34381 cacgtaacta tgtacgtcgt atctcagagc ttgttggtgt acgtatctca acattttctg
    34441 tcggacctga tagaacacaa acaaacatct tagaaagcgt ctgggcgcaa atctaaggat
    34501 aaaaacgacg actgaatcag gacgttctta ccagagcgag tcgaagtgtt tatctatacg
    34561 ataataataa cttgaagagg tagtgaaaga gacgtttagc cttattgccg ataggctgtc
    34621 tcttgaacac tgtttattca gaataaggga ctgtgacaaa aaccgtgtca cagtcccttt
    34681 ttccgaa
//
LOCUS       DBBGSZ010000028        32679 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.028, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000028 DBBGSZ010000000
VERSION     DBBGSZ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32679
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.028"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..270)
                     /locus_tag="ACIZE5_001821"
     CDS             complement(<1..270)
                     /locus_tag="ACIZE5_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HGC6108948.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCG"
     gene            543..3014
                     /locus_tag="ACIZE5_001822"
     CDS             543..3014
                     /locus_tag="ACIZE5_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGC6108949.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(3117..4853)
                     /locus_tag="ACIZE5_001823"
     CDS             complement(3117..4853)
                     /locus_tag="ACIZE5_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC6108950.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(4850..5554)
                     /locus_tag="ACIZE5_001824"
     CDS             complement(4850..5554)
                     /locus_tag="ACIZE5_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC6108951.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5685..6188
                     /locus_tag="ACIZE5_001825"
     CDS             5685..6188
                     /locus_tag="ACIZE5_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HGC6108952.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            6148..6486
                     /locus_tag="ACIZE5_001826"
     CDS             6148..6486
                     /locus_tag="ACIZE5_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HGC6108953.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6507..7925
                     /gene="ffh"
                     /locus_tag="ACIZE5_001827"
     CDS             6507..7925
                     /gene="ffh"
                     /locus_tag="ACIZE5_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HGC6108954.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            8037..8615
                     /locus_tag="ACIZE5_001828"
     CDS             8037..8615
                     /locus_tag="ACIZE5_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HGC6108955.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8619..9140
                     /locus_tag="ACIZE5_001829"
     CDS             8619..9140
                     /locus_tag="ACIZE5_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HGC6108956.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(9219..9773)
                     /locus_tag="ACIZE5_001830"
     CDS             complement(9219..9773)
                     /locus_tag="ACIZE5_001830"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGC6108957.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            10026..10301
                     /gene="rpsP"
                     /locus_tag="ACIZE5_001831"
     CDS             10026..10301
                     /gene="rpsP"
                     /locus_tag="ACIZE5_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HGC6108958.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            10313..10564
                     /locus_tag="ACIZE5_001832"
     CDS             10313..10564
                     /locus_tag="ACIZE5_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HGC6108959.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10689..11480
                     /locus_tag="ACIZE5_001833"
     CDS             10689..11480
                     /locus_tag="ACIZE5_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108960.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11650..12171
                     /gene="rimM"
                     /locus_tag="ACIZE5_001834"
     CDS             11650..12171
                     /gene="rimM"
                     /locus_tag="ACIZE5_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HGC6108961.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            12161..12922
                     /gene="trmD"
                     /locus_tag="ACIZE5_001835"
     CDS             12161..12922
                     /gene="trmD"
                     /locus_tag="ACIZE5_001835"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HGC6108962.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            13058..13405
                     /gene="rplS"
                     /locus_tag="ACIZE5_001836"
     CDS             13058..13405
                     /gene="rplS"
                     /locus_tag="ACIZE5_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HGC6108963.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            complement(13441..13626)
                     /locus_tag="ACIZE5_001837"
     CDS             complement(13441..13626)
                     /locus_tag="ACIZE5_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108964.1"
                     /translation="MLEYSGFFIKAVTLKKDIIIVLFFLLLLIGRFILIHYSPLPIIK
                     EKTGSGCSNYMLRKKNP"
     gene            13663..13956
                     /locus_tag="ACIZE5_001838"
     CDS             13663..13956
                     /locus_tag="ACIZE5_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HGC6108965.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(14044..14190)
                     /locus_tag="ACIZE5_001839"
                     /pseudo
     CDS             complement(14044..14190)
                     /locus_tag="ACIZE5_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332517.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamate
                     endopeptidase"
     gene            14799..17126
                     /locus_tag="ACIZE5_001840"
     CDS             14799..17126
                     /locus_tag="ACIZE5_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBG domain-containing protein"
                     /protein_id="HGC6108966.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            17123..18037
                     /locus_tag="ACIZE5_001841"
                     /pseudo
     CDS             17123..18037
                     /locus_tag="ACIZE5_001841"
                     /inference="COORDINATES: protein motif:HMM:NF027869.4"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
     gene            18110..18625
                     /locus_tag="ACIZE5_001842"
     CDS             18110..18625
                     /locus_tag="ACIZE5_001842"
                     /inference="COORDINATES: protein motif:HMM:NF037639.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prealbumin-like fold domain-containing protein"
                     /protein_id="HGC6108967.1"
                     /translation="MDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFT
                     SSKDGTFSVHGLSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEP
                     KANPTNNGKTPVQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKK
                     QQKGNNRREIK"
     gene            18762..20051
                     /locus_tag="ACIZE5_001843"
     CDS             18762..20051
                     /locus_tag="ACIZE5_001843"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HGC6108968.1"
                     /translation="MKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKD
                     TAVPADATPFASVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLPF
                     YNPNSSDPDKPLDTIHLYAKNVIKESNIKIQKAGNFSGVDKLAGAQFQIKNSENQFVT
                     GFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVETKAPDGYQLTNPQKET
                     TFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTITVENVQNYGDFHFIKQ
                     DVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWSDEVTGSDWEEVKLISD
                     SEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDDDPTTSDETTIDNQPKG
                     ILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            20257..21429
                     /locus_tag="ACIZE5_001844"
     CDS             20257..21429
                     /locus_tag="ACIZE5_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HGC6108969.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(21591..22265)
                     /locus_tag="ACIZE5_001845"
     CDS             complement(21591..22265)
                     /locus_tag="ACIZE5_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108970.1"
                     /translation="MKKLVALFLVAGSLLSGCGATTSTTQSTSSAQASSSSTTISEST
                     ADSSKEQEQIEKKKEEEKQKAEKAALEKKVTEAESALSQAEANPTKENYATASAAIQA
                     LPENKQELTSRLAAIDSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQ
                     AAAEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPC
                     SKCYGN"
     gene            22636..23058
                     /locus_tag="ACIZE5_001846"
     CDS             22636..23058
                     /locus_tag="ACIZE5_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6108971.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            complement(23224..24417)
                     /locus_tag="ACIZE5_001847"
     CDS             complement(23224..24417)
                     /locus_tag="ACIZE5_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6108972.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            24641..25018
                     /locus_tag="ACIZE5_001848"
     CDS             24641..25018
                     /locus_tag="ACIZE5_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGC6108973.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            25006..25344
                     /locus_tag="ACIZE5_001849"
     CDS             25006..25344
                     /locus_tag="ACIZE5_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGC6108974.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            25478..25921
                     /locus_tag="ACIZE5_001850"
     CDS             25478..25921
                     /locus_tag="ACIZE5_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HGC6108975.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            26183..26998
                     /locus_tag="ACIZE5_001851"
     CDS             26183..26998
                     /locus_tag="ACIZE5_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6108976.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            27008..27670
                     /locus_tag="ACIZE5_001852"
     CDS             27008..27670
                     /locus_tag="ACIZE5_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HGC6108977.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            27875..29539
                     /gene="alsS"
                     /locus_tag="ACIZE5_001853"
     CDS             27875..29539
                     /gene="alsS"
                     /locus_tag="ACIZE5_001853"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0034077 - butanediol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HGC6108978.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            29552..30262
                     /gene="budA"
                     /locus_tag="ACIZE5_001854"
     CDS             29552..30262
                     /gene="budA"
                     /locus_tag="ACIZE5_001854"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HGC6108979.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            30392..30889
                     /locus_tag="ACIZE5_001855"
     CDS             30392..30889
                     /locus_tag="ACIZE5_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HGC6108980.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            31074..31334
                     /locus_tag="ACIZE5_001856"
     CDS             31074..31334
                     /locus_tag="ACIZE5_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108981.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVIGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(31696..31935)
                     /locus_tag="ACIZE5_001857"
     CDS             complement(31696..31935)
                     /locus_tag="ACIZE5_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108982.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            32221..32535
                     /locus_tag="ACIZE5_001858"
     CDS             32221..32535
                     /locus_tag="ACIZE5_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108983.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT        11017 a         5744 c         6515 g         9403 t
ORIGIN      
        1 tccacaatca tggcagagaa aacgggtacg ttttaattct aaaatagtta acttttcttt
       61 gactttcaac atctgagtgc gtgtcgtata ggaaccgttg cggataatac gaaccgatcg
      121 acagtgttca caataggaag aagagtcatc caattttcct ttaataaact gcgcttgaac
      181 gcctttatat tctttttcaa tcagccattc ttcatcaaaa aataaatgtt tatctgttaa
      241 tccgagtaat tttctagtat gattatccat tgagagactc ctttggtagg atgacgtttt
      301 ggtcgactaa attttaccaa aagtgagtct ctttttgagt tgaaacgaag aaaaagtgtt
      361 agtagaaaat cgccttcgat tttccaccaa cacaaaatat tatagaaccc tttttttttg
      421 ctatatgaca ggaatgaaag gtgtttgcaa gcttaatgtg aggaacactt tccatatctg
      481 ttctatactg gataggagaa gtttggaaat atccagaaaa cgaaatcaat cgaggtagcc
      541 acatgaagaa taaatggata aatcgaagta aaaaaaagaa agtaacacaa agatcatcag
      601 ataaagtcat ccgtcttttt ccatcgtata aagaaggatt aacggcagat caagtcaagg
      661 aacgaataga aaaaggtgca gcaaataatt cagtcgatcc cacattcaaa acaaatcagc
      721 aaatcgtatt ggaaaacata tttacgtatt tcaatttgat ctttcttatc ttagccattt
      781 tgctttgttt agtagaatcc tataagaact tgactttttt accagttatc atagccaata
      841 caggaatcgc catttttcag gaaattcgat ccaaaaagat cttggacgaa ctaaatgttt
      901 taaatacagc aaaagtcaat gtcatacgag acgggataga acaaacaata gatatagaag
      961 accttgtaat agatgacatt gttattttag agactggata tcaaattcca gcagatgcag
     1021 aggtcgtgga agggaaactg caagttaatg aggctttatt gacaggcgaa gcagatgaaa
     1081 taaccaaaga aataggtgat ccattaatgt ccggcagttt cattgtttcc ggaaaagctt
     1141 acgcccgatt agacaaagtt ggagcagatt cgtatatttc ccagctgaca gtcaaagcca
     1201 agacaatggg agaaggagaa cagtcggaga tgattgcttc tcttaatcaa ttgatcaaat
     1261 ggattgggat catcattatt cctatcggta tcctgctttt ttctcaaagt tactttttta
     1321 atggaaacac gatcaaagaa agtgtcgttg caatggaagc agcattgatc ggtatgatac
     1381 ctgaaggact gtacttgctg acgacgattg cattagcatt aagtgcgact aaactagcaa
     1441 agcaaagagt tcttttacac aatatgaaaa gcattgagac attggcaagg gtaaatgtcc
     1501 tttgtgtaga taaaacagga acgatcacag aaaataaaat gtctgttcaa aaaatgatcg
     1561 tctctaaaaa acaagaaata atcagtcagt cagatcaatt ggaagcatgc attgctgact
     1621 atgcaaaagc gatggcagga gacaatgcaa caatggaagc tgttaaagca tattttacaa
     1681 aaaccactga tcaatcctat caccatgtta ttcctttttc ttctgtccaa aaattcagca
     1741 gtgtagcgtt ggcagacaag gtgtatgttt taggagcgcc cgaaatggtt ttgcgcgatc
     1801 aattgccgga atatgcggaa gagtttgttt ctttcgctga aaaaggctat cgcgtgttgg
     1861 tctttggtgt gtacgatggg attcttgaag aaccagtatt gacagaagca gtcacaccat
     1921 taggctatat tctgattgct aatcctatca gaaaagaagc aagagccaca tttgattact
     1981 tcaaaaaaca gcaagtagcc atcaaagtga tttctggaga taatccgctc accgtatcca
     2041 atgtagctgt ccaagcaggg atttcacatg ctgatcagta cgttgatgca tctaaattat
     2101 cagaagaaga atatgaagca gctgtcgaaa aatatacagt ttttggacgc gtcaagccag
     2161 aacaaaagaa aatcttcgtt caattgataa agcgtaacaa tacagtagct atgacaggtg
     2221 atggcgtgaa tgatattcta gccatgaaag aagcagactg cagtatagcg atggcttccg
     2281 gaaatgaagc cgccatgcag gcctcacaag tggtcttact tgattctgac ttttcacgca
     2341 tgccagaagt tgttgcagaa ggacggcgcg ttgtgaacaa tattgagcga tcagccagct
     2401 tgtttttagt gaagaatatt ttctcctttt tgctctcact gttttcagtg atctttgctc
     2461 tgacctatcc tttagaacca tcacaaatca cattgattag tttgtttact atcggacttc
     2521 catctttctt gcttgctcta gaagaaaaca aaaagcgaat cagagggaaa ttcatcatga
     2581 atgtgatgga aaaagctgtg ccaggtggac taacagatat gatcgtagtc ggtgcgttgg
     2641 tgatctgcgg ggtgactttg aatctaaata aaacagatgt ttctacagca tctaccatgc
     2701 ttttgattgc agtagggttc ctcgttctct ataaaatctg ttcaccgctg aataaattca
     2761 gaagtcagat cattcttttc tgtgctagcg gtaacttttt ttcggtcatc tttttgcata
     2821 agctgttttc aatcaccggt atctcagctg tatcactttt gctgttgagc attctatttt
     2881 tctcggcaga ttcgattttt aggcatttga ccacattggt agaatatttg tttgaacgta
     2941 aaaatgaaaa agagcaaaag ccgtttagtc gcgtagctaa aaaatttcta tcgatattta
     3001 aacgagaaaa ttgacgaaaa gtatctcaaa aaagagtaaa aaagaacaac cactcgtgta
     3061 tctttcgaag caggatgagt catccaactt taaaacgcac gagcagttgc tcttttttac
     3121 attttcggaa tggtaacggt gaaagtcgaa cctgttccaa gatgactgtc tacagtaatc
     3181 gtaccattaa ggagttgcac gtagtctttt acaatcgcta accctaatcc ggtcccgcct
     3241 gaatgtcggc ttcgcgcctt gtctacgcgg taaaaacgct caaagatccg ttcctgatcc
     3301 tcaatgtcga tacctatacc aaagtcttgg acagaaaacg atagatcatc tgttgcctga
     3361 tagcggataa taatctcgct gtcgcttttt gaatattgga cagcattttc aatcagattt
     3421 ttgataattg gataaaggat atctgtttta gtagtaaatg gttcgttctt tccaatcaat
     3481 cgaatcgtca accgtttctt ttcgatgatt ggctgataat tttgaacgat ttgctggaaa
     3541 taaggttctg tataaattgt ctggatctcg taagaattct cgccatcttt tgacagctgg
     3601 atgatttccc gaatcagttt atctaaccgg atcgcatctt tttgcatgat ctcaagaaaa
     3661 gaagtcagag tttgcgggtc atcttttgca ccatccagta aagtctcggt aaaaccaatc
     3721 agtgaagtca caggagtttt taattcgtga gagacgttgc caacgaaatc cttttgtagc
     3781 ttttctaaac gtcgcacttt cgttaagtca tacgccaccc ctagaatctg tccggtacct
     3841 tctgaattag taaagtagcg caaactcaag tctaatgtct gccgaccttc tgtaagggtg
     3901 atctcctgat ggatcagcgg atgctcagga gtcacttgat gaatcagctg aatgagtttt
     3961 ggctcttgaa tgacttctgt gtaccgctgt tcaggttgat agcttaccac gtttaaatgt
     4021 agctgcatct ttggattaag cagtagtaaa cgagaatcag catcatcaat caggaatacg
     4081 ccaatcatca gttcgttcag taacgtatat aattgctctt ctgtggtagt acacgcccga
     4141 tacatcttac tcatttgttc gctcaacgca ttaatcgtct gatacaattc ttcccattga
     4201 tcgggtgttt gcatgattac ttccgcctga ttaggatttt gcaccatttt ttttagtacg
     4261 ggcagcacgg ttttcaatgg ctggtttttt tgatagatca gataatagat cattcctgca
     4321 agaacaagga agaaagacag aaagaagaaa aagacccaac ggcgaaaact ctcagttctc
     4381 ggtaaaaaaa cgcttgtcgg ttctgcgata cgtaaaatgg cttctaactg gccacttttt
     4441 ttgactggta atgcgacata taaaagatcc tcattcaaag tagtactttt gcgcaaagcg
     4501 ctacctaggt tcccaccatt caatacggct ttgatttcgg gacgggagtt tcgctgttca
     4561 ttcaatgttt cattgtttgt gtcaaataag atctttccag tagcatccat taaagtaatc
     4621 cgttcgttcg actgatggac gaattcttcc aaagcagttt tgttttgcgc tgcttggagg
     4681 ttttcgacat ctaattgccg gatcagcagt tgtgcttttt ttgtcaggta gctttcttgc
     4741 tgttccacga tctgctgttg aaaataatgg gaaatcaatt gccagccacc aaaaaacaaa
     4801 ctaactaaaa gaataagaaa gaagagacgt tcataaattt ttttccattt catcgtttgg
     4861 gttcctgaaa cttatagcca aatcctctaa tagtcaccaa gtactttggg tgttttggat
     4921 ctcgctcgat tttttctcgc aaatgactaa cgtgtacatc tacgattcgg ctttgtcctg
     4981 cgaagtcaaa attccaaatg cggtctagca atgtgtctcg gtcgatcaca cggtcttttc
     5041 gtttcatgaa ataaacaagt aattcaaatt ctttcggtgt tagttcaatc agatggtcgt
     5101 ctacggtcac ttgataattg gtcaaatcag cagtgatttg tccaatcgat agatattcag
     5161 gctcagcttc atcttttgat tgcttacgag gttcaattcg tctgaatatt gctttcatac
     5221 gggctaatac ttcgcgagga ctaaatggtt tggtcaaata gtcgtcagca cctatttcta
     5281 ggccaatgat ccgatccact tggtcatctt tagccgtcag catcaaaatc ggtgtttcat
     5341 ttttttcttg acgcagccgc tgagtgatct ccatgccatc catcgttgga agcatcacat
     5401 ctaaaatgat gaaatcaaat gattgttcta atgctaattc taatccttcg cctccatctg
     5461 tggcactggt taccttgtag ccttcttttt ccaaattgaa cgtcaagagc gttacaatag
     5521 aaggttcatc atcaacaact agtatttttt tcattcaaat ctcctttaaa taggtttcat
     5581 tctgtttata ttttagcata gaatcagtac aaagggctat tttacaaaag aaataaatgg
     5641 tataatagga aggcactttg ctgaatagaa aggaagagca gtcaatgatt ggaatcagtg
     5701 catgtttagg cggtctggcc tgtcgctatg atggacagaa aaaagaagta ccagaattga
     5761 tggaactagt tgaaactgga gaagctgtca tggtctgtcc agaagtgatc ggcggattac
     5821 caattcctag agatcccgct gaaatcattg gtggaaatgg attcgatgtg tggaaagatc
     5881 aagcaaaagt atggacgaca agcggcgaag atgtaacgga agcgtacaaa aatggcgcga
     5941 tcaaagccta tcaaaaattg caggaaaaac acattgatct agtcatcatg aaggaaaaaa
     6001 gcccttcatg cggaacccat tcgatttatg acggaagttt ttccggaata aaaaaaaatg
     6061 gtgccggagt ggctactgct tattttattc agcaaaaaat gactgtgctc tctgatgaag
     6121 aatggctgaa aactagaggt gagcagaatg gaaatcgaaa agaccaatcg aatgaacgcg
     6181 ctctttgaat tttattcgac cttattgaca gaaaaacaaa tgaactacat ggaattatat
     6241 tatgcagatg atttttcatt aggtgagatc gcggaagaat acgaagtaag ccgacaagca
     6301 gtatatgaca atatcaagcg gacaagcaag atcttggagg attatgaaaa aaaactccat
     6361 cttttttcta attatattgt tcgagaacag gtattggaaa atatgactgc atatattaca
     6421 gataagtacc cggaagataa aaaactactt gaatatgtac agcaaattca agcaatcgaa
     6481 gaataaataa aaggaatgaa gaaaatatgg catttgaaag cttaactgaa cgtctccagc
     6541 aggcgatggg aaaaataaga aaaaaaggaa aagtatcaga agctgacgta aaagaaatga
     6601 tgcgggaaat ccgccttgcc ttactagaag ccgatgttaa cttgcaagta gtcaaagatt
     6661 ttactaagcg cgtacgcgaa cgtgcggtag gggcagaagt gctggaaagt ttatcacctg
     6721 cacaacaaat cgtaaaaatc gttgatgaag aattgacgat cacacttggt tctgaaacag
     6781 cagagttaaa taaatcacca aaaataccaa ctgttatcat gatggctggt cttcaagggg
     6841 caggtaaaac gacctttact ggtaaattag ccaattattt aaagaaaaat gaaaatgctc
     6901 gtccgctcct aatcgcaggg gacgtatatc gaccagctgc gatcgaccaa ttgaaagtat
     6961 taggtcaaca gctagacgtt cctgtatttg atatgggaac tgaagtcagc ccggtagaga
     7021 tcgtccgtca agggatggag ttagcaaaag aaaagaaaaa cgactatgta ttgatcgata
     7081 cggcaggacg tctgcatatc gatgaaacat tgatggatga gttgaaacaa atcaaagaat
     7141 tgacgcaacc aaatgagatt ttgcttgttg tcgatgccat gactggtcaa gatgccgtca
     7201 acgtagctga tagcttcaac cagcaattag gtattacagg ggtcgtcatc actaaacttg
     7261 atggggatac tcgaggcggg gcagcactat cgatccgctc agtgacaggc gcaccaatca
     7321 aattcatcgg ttctggtgaa aaattgactg acttagaagt attccaccca gatcgtatgg
     7381 ctagccgtat ccttggtatg ggggatatgc tgacattgat tgaaaaagcg cagcaagact
     7441 acgacgagaa aaaagcggaa gaacttgcac agaaaatgcg ggaaaattca ttcgatttca
     7501 atgactttat tgaacagctt gatcaagtga tgggtatggg cccactggaa gatctaatca
     7561 aaatgatccc aggaatgaat caagtccctg gaatcgaaaa cgtcaaggta gatccaaaag
     7621 atgttgaacg caaaaaagcg atggtttatt ctatgacgcc agcagaaaga gcaaatcctg
     7681 atctgttgaa cccaagccgt cgtcgccgaa ttgctgccgg ttctggaaac agtgttgttg
     7741 aagtgaatcg aatgatcaaa caattcaagg aatcaagaaa aatgatgcag caaatgtcca
     7801 aaggggatat gaacatccca ggtatggacc aaatgtttgg ttcaggcgtc aaaggaaaac
     7861 taggcaaaat ggcgatgaat cgaatgatca agaaaaataa gaagaaaaag aaaaaacgga
     7921 aataagatga aaaaaacagc ttcggtacag actgaaaatg tctactgccg gagcttttct
     7981 atcagcaatt tttattcttt actaatacaa ttactctaaa cgaagaggtg gcacagatga
     8041 gatgtccgtg gagtgaacaa acagaaagta tgcggcaata tcatgatact gtctggggtg
     8101 ttcctgaata tgatgaccaa aagctgttcc gaaaattgat gcttgatatt aatcaagccg
     8161 gattgagctg gcagacgatt ttaaataaaa gtgaagcatt cgatgaagca tatgatcgat
     8221 tcgatatcaa aaaagtcgca aattatggag aaacaaaaat cagtgaacta atggaaaaca
     8281 aaggaattat tcgtaaccga agaaaaatcg aagcagccgt ccaaaacgcc aaagcagtct
     8341 tgaaaattca agaagaaatc ggcagttttt cagagtatct ttggtcgttt tctaatggaa
     8401 aaatcgttga ttcttcttat cattcacaag aagaagtccc aacaacaagt cctctttcag
     8461 atgaattagc aaaagatcta aagaaaagag gatttaaatt tatcggaagc acaacaatct
     8521 atgctttttt agaagctgtc gggatcatca atgatcacct tgacagttgt ttccgcaaag
     8581 aagaggtcgt acgtatcggc agaaagggcg aataaagcat gcgaaaaatc atattttatg
     8641 gtgctataag tttagatggc tatttggcaa cgaaaacgga tgatcttcaa tggctttttg
     8701 acactccaac aggtaagcaa actacttatg aagcttttta tgaaacaatc gatacgacca
     8761 tcatgggcag aaaaacttat caggaagcaa aaaaatattt ggagaccgaa gcaatttatc
     8821 cagagaaaaa gaatttcgtt ttttccaccc acgcacaatt acaattgcca gatgctgagg
     8881 tcgtaaacga agatcctgtt gcttttctaa aaaatctaca aatgacagaa ggaaaagata
     8941 tctgggttgt gggtggcggt cgattgatca aaccgctatt ggaacatcaa atgattgatg
     9001 aatggtatat ccagattacc cctgtattat taggggacgg gattccttta ttccaaaaag
     9061 gaacatatga agcgcgtttt gaaatgctag acacgacacg attcggtgaa tttatcgaat
     9121 tgcattatgt acgaaagtag aagtaaataa aataaaaaag gcaactatat gcagaaatgt
     9181 cctgtacata gttgcctttt ttattaccgt tatgcttttt actctgttaa tttgttagaa
     9241 aaatctagat acgcatctaa aatcgtttgg aagaaactta atgttccttc aacgatatta
     9301 ccattttcat caattagatt cgcaacgttt ccgatatatg cttccggttg ctgcaaggtt
     9361 ggcacattca aaaagacaag tgattggcgt agatggtggt ttgcgccaaa gccgccgatc
     9421 ccacctggtg atgcagtaac gactaaacct ggtttatgat cccaaacact gtgtccataa
     9481 ggtcttgagc ctacatctaa agcatttttc aatactgctg gcacagaacg gttgtattca
     9541 ggagtaacga aaacgacacc gtctagtccc ctcacttcct cacgaaaacg agtccattca
     9601 gcaggagcct gttctggagt ttcgagatcc tcattgtaaa atggcagatc atcgattttt
     9661 acaaatacac tttcgtaccc ttcaggaagc aatttcgcaa aagcttctgc tacttttttg
     9721 ttgtaagaat cttttcttaa actaccaata aaaaatccaa ttttttttgt catacgattt
     9781 ttcctccttc aaactatcta taataatctt acaaaagata agtaactgga gcaaataaaa
     9841 acacttactg acaaaagcta catagaagat agattactta tttttaacaa aaaagaagtc
     9901 taaaatcttc tattttctaa aaaaaatcga atttaatcaa gctgtaaaga aaaaaagctt
     9961 tacagggtaa aaaaaaactg ttacactaca tcttgtgaat aaaacaatgg aggtggaaat
    10021 aaataatggc agttaaaatc cgtttaaaac gtatgggttc taaaaagagt ccgttttacc
    10081 gtatcgtcgt agctgattca cgttctcctc gtgatggacg tttcatcgaa actgtaggta
    10141 cttacaatcc tttgaaagac cctgcagaag tagttttaaa agaagactta gttcttgact
    10201 ggttatcaaa aggtgcacaa ccttctgaca ctgtacgtaa catcctttca aaagaaggcg
    10261 ttatgcaaaa acaccacgaa gctaaattct caaagaaata aggtgaccgg atatgaaaga
    10321 tttaagcgac ttagtcttaa caatcgttcg tccgctagtc acttatcctg atcaagtcaa
    10381 gttagacgtc gtagagtcga aagactttta cgagtacaat ctaacagtgg ctcctgaaga
    10441 tattggccgt atcattggaa aacaagggcg tgttgctaaa gcaatccgca caatcgttta
    10501 cggtgttcgg atcaatgcac cgaaaaaagt gcgtttgaat atcatcgatg ataaggaaaa
    10561 gtaaataaac gtgctgtact cgaattttcg agtgcagctt ttttgttttt tttattaatt
    10621 gaagaaatga ttatttggca aaacaagcaa gaaagcgtat ccttatagga ggagggagtg
    10681 aacagccaat gagaaagaaa atgttattta ttccatttgc tctattgtta agcgcttgta
    10741 gttcggttac tcaagaatca gacaatacac atctatcaag cagtatatct gaaactgtta
    10801 ccagtccaga aaaaagtagt accaaaacgg cttccaccac tgaacaaaca atggctacct
    10861 caaataatga gaaaaagact gctttagacc agttgaaaga acaacagcca aatgttccca
    10921 tgcctctaga tgtaccagtc tcttcaggct atctcaatat cgcagcgaca catacaaagc
    10981 aaggttattc tattttatat tacagaacag atcgtcccct cgggttgaat gctgacgaat
    11041 tgaatcaaga aacgcctatt gcaacctatc tatatcaata tgggtttgct tctagtcaag
    11101 aaacaatcca agttttgcag ccatttgaga tcgacacaaa tggtcagcaa gtggacttag
    11161 gttctcgaat cacagggtat cagcaaggtg cagcaggttc aagttttctt gaatggcaag
    11221 aaggaaactg gcgtattcga atccgtggga ataatataga aggccaagat cccttactat
    11281 tagctaaaga aatcgtagct tatttggaag aaaacagtct accagcacct gaacaatttg
    11341 gtaaaattac tgttgatatg ggtgatacga cgaatcgagc cgtagaagta agctggcaag
    11401 aaccgaaaaa tgcctatacg atcactcatc aagatcctat gtctgcgttg aagatggcag
    11461 tttctatgaa gaggttgtga aatcagcgcg ctgatctgag cccatcattt aactccaagt
    11521 cacaggaagt aatcaaaaat agcacgccgc atttttgcat aattttggct taatacctta
    11581 aaagaaaact agaattgcct cttcacacat gctaaaataa aacagacaaa aaagaaatgg
    11641 ggatataagt tgactgaata cttgaatgta ggaaaaatcg taaacacaca aggtatcaaa
    11701 ggcgaagtcc gtgttatctc aacaacggat ttcccagaag aacgttacaa aaaaggaacg
    11761 gtgctaacac tattccaaga cggaaaagca cctgtggaat taacagtcaa aagtcatcgc
    11821 aaacataaaa attttgactt attgagtttt gaaggacatc cttctatcaa tgatgtggaa
    11881 aaatatcggg atggcatatt aaaagtgtca aaagacaact ctgtagatct agctgaaaat
    11941 gaattctatt accatgagat catcggtctg catgtattag aagatggaac tgagttaggt
    12001 aaagtaaaag aaatcttgtc accaggtgcc aatgatgttt gggtcgttca acgtccgaaa
    12061 aaagctgata tattgcttcc atatatcgct tctgtcgtca aagaagtcga tttagaagct
    12121 ggagtggtcc gtgtagaaat tccagaagga ctgattgacg atgaagattg atgtattgac
    12181 tttatttcca agaatgtttg aaggtcctat gggggaatcc atcatcggta aggctgtaga
    12241 taaaggatta ttagatatca atatctctaa cttccgcgat tattcagata acaaacatca
    12301 gacagtagat gattatccat acggcggtgg agcaggtatg ctgctcaaag tccagcccat
    12361 ctatgataac atccaagcca ttgaaaaagc tgcaccggat gtcaaaaaaa gagtaattct
    12421 tcttgaccca gctggtaaac gattcgatca gaaaatggca gaagaatttt cacaagaaga
    12481 acacttagta ttcatttgtg gtcattatga gggatatgat gaacgtatcc gcacattagt
    12541 gacagatgaa gtttccttag gagattatgt ccttactggg ggagaattag gtgcgatggt
    12601 catgatcgat gcaacagttc ggcttttgcc agatgtgtta gggaatcaga cttcagctca
    12661 aacggattct tattcaaccg gtttattgga acatccccaa tatactcgcc cggcagaata
    12721 taaagggatg aaagtaccag aagtattgac aaatggaaat cataaattga ttgaagaatg
    12781 gcaattaaaa gaatcactaa gaaggaccta tcaacgtcgg cctgatcttt tggaaacact
    12841 tgaatggaca cctcaaatga cgaaattttt agaagaaatc aagaaagaag aacaagaaaa
    12901 aacagcagat gaagccaagt gactttttct aaaatcttct ttacagtagg ttgataatat
    12961 gttagtattt tatggtgagt gcaaaagcac ttaactatta cgatattccg ctgtgagaaa
    13021 agctcataag aatatttgga ataaggagaa gaaaaccatg aatccattaa tcgaagaatt
    13081 aacaaaagaa caattacgtt ctgacatccc agcgttccgc cctggtgaca ctgtgcgtgt
    13141 tcacgcaaaa gttgttgaag gtactcgtga acgtatccag ttatttgaag gtgttgttat
    13201 caaacgccgc ggtgctggaa tcagcgaaac ttatacagta cgtaaagttt ctaacggagt
    13261 gggcgttgaa cgtacattcc cattgcatac accacgtgtt gcaaaaatcg aagtagttcg
    13321 ctacggtaaa gtacgtcgtg caaaattgta ctacctacgt gcattacacg gaaaagctgc
    13381 tcgtatcaaa gaaatccgtc gttaatcatt gttatcagac tgagaaagaa cccttggtat
    13441 tcaagggttc ttttttctta gcatgtaatt tgaacaccct gatccagttt tttctttaat
    13501 tattggtagg ggagaataat ggattagaat aaatctacct ataagtagta gtaaaaaaaa
    13561 gagcactatg ataatatctt tcttaagagt aaccgcttta ataaaaaatc cagaatattc
    13621 taacataaat ggagtattct tagaatcaaa aggagaaaga agatggttta tacttatacg
    13681 gagcaagaaa agatgaaagt tttagacaca ttcatgaatg atggaaaagt aaaacaagta
    13741 ccaagttcaa caaaaaagaa atacatccta ttgaaagaag tcttgaaacg ctttgaccat
    13801 ggagtgactt atacagaaac agaggttaat tcgatactgc tgaacgtatt ttctagtggc
    13861 gattatgtcg aacaaagacg ttatctaatc acatttggct ttttcaaaag aagttcagac
    13921 ggtcgggcat atcagatgat gggaattgaa aattagaagt tttaatttat actcattgaa
    13981 aaaagttcaa gtatgcgata ttggttctac accgcatact tgaacttttt ttgtcatctg
    14041 tatctataat acaaagccaa gaacgttatt caaaatatgg atagctatga taaaagctaa
    14101 tgagcgattc gcagttaaat aagcaatcgt cagtaaaatc gttccaggag cgtacatgaa
    14161 aaaatcaatt ggatgcgtta catgaataaa gataattctc ttttatttgt acgaataaat
    14221 accaaaacgt acctcctaaa attagatttt ggacagatgc cctttaaaaa gataacaaga
    14281 tttcgttctt gaaacaatat atatgctttt attccaatga ggttgtgaaa acagtatttt
    14341 gtcctgagcg ttagaaaatt gaaaatgggg aatagcaact cgtactttac cattttttaa
    14401 gtgaatacaa gatcagctaa ttgaacaccg tttattcgtg atgagggaca caacactgca
    14461 gtcgacacat ttctctttta tgttcaaaga taacaaatat ttaaaacaaa gaaaaatagt
    14521 agataatccc gtcctaactc ttttattctt ccctcatagc ttccaaattt aagcaatact
    14581 tcaattaatc aagttttatc tttttttttc aataatcgta aaaaaagagt attttttatt
    14641 taaaaataaa atctttgtat taaaggacaa gactaaaata accttagaat aaaaagagaa
    14701 aaaaagcccc aaactttcta tacatcaata aaataataaa aattaaattt agaataacgt
    14761 gtaaaggatt atttgatgat tttttattga gaggagggat gaaaatgatt aagaaaactc
    14821 aaaataaaat ccaacgtata tgtcaaaaac attttgtttc tagactcaaa gctgtatcta
    14881 aaagaaaata cttacatccc attatgattt cgatcatctt gatttttact ttcttaggga
    14941 gcttatcaag tatttatgta aacgtttata cagaaacgtc aaattttgct aaccaaacga
    15001 cagaggagac aaatagtcca ccctattctg aaatacagtc catagaaagc accaatcagt
    15061 ctagcaacaa cgagacaacc tcaaccacat cctcgactca actgattgat ccgacagaaa
    15121 aagaaatcac agcagcaaaa gcagcagggg agaaagctta ttcagaaaca ggtagaagcc
    15181 agacatttag tactgttgcg gccactgcga atttcaacgg acataccata ccagatggat
    15241 atacagtgat atatgccaaa gatggagtca ttgttgcggt taacggatcg atgagtgcgg
    15301 ataaaactgc gttacaaggc gtaaccaaag caatcgcttt tattgataac cgtccagata
    15361 tccataatct gtttattggc tccacagtaa atggtactac tatcacattc ccaaaaagta
    15421 tctatatggg ggtggctacc gctggaaata cgatcgattc agttacaccc aatgcggata
    15481 aaagttattc ttttacaccc tcaacatggg gagggcttcc tgccggagga ggtatgagta
    15541 ctttttcaat cggtatacag ttagcaaatg atattccatt cacggggtac tcgatcaaaa
    15601 atgggcagat cgttgatggt aagggaaatg tttcaaattt tccaacctat caagcagcaa
    15661 cggttcaggt caatgcgaat cggacaggaa ctttttctta tacagtcaat ggtggagcag
    15721 caaaaatcgg aacgtacggg actacattat ctggaatcca tgtgggtgac aaagtggtta
    15781 tcactccaac agcagtaacg ggctattctt ttgcacaaac aaacggttct ttcacagccc
    15841 tagaaagtaa cgtcgatacg gtgacctata caggcaaaca aacaccaatc actattaagt
    15901 atcaagacta ttttggacag atgattgctc cttctaaaat aatgaatctt acttacggaa
    15961 gtgctgcaca agacctgacg actaatacgc ctactatcaa cggatatacc tttacagctg
    16021 tttcagcgac agaaacaaag aaccaatcag caatgagtgt tttagctagt ttagatacaa
    16081 atggaaatgt aatcgtaaag gacgcaaatg gaaaacagat ttctgaagtc atcctatatt
    16141 ataagacaaa tgcaacagta tcaatcaatg caaatggcag taagtactat gatggtcttt
    16201 ctgttgtacc gatcgttaaa tatgccttta atgataaaac agaatcaaca tcccttttaa
    16261 acaatgatct cagtattgat caaatcacat ggaatccaac tgatttcaaa gcgatgaatg
    16321 aaaagggagt tgaagtaact gcgcctactg aaattggaac ctatacgtct tggcaattga
    16381 caaaaagcgg actagctaaa ctagctgcca gaacaaacta tttatttact atcgtgcaga
    16441 catctgatgt ctatacgatt aagcaaatca gcggtgcggt agagctcagt ggcagtaaga
    16501 catatgatgg aaaagcaggt gtcccgtcaa tccatgtcaa gctagcagag ggtgtcacta
    16561 gttcgcttac tccagtacaa gtggcactta gcagtatgga ttacacagca gatgcacaat
    16621 cagcaaaaaa tatggttaat gctggcagct atacaattaa actaacgaat agcggaatag
    16681 acaaagtcaa agcagcaaat cccaagttgt catttactga tatagccaac acatcaggaa
    16741 cttataccat ctataaagct aacgcagtga ttactgtcga tgacgctgcc tttaattatg
    16801 atgcccaaag tcactcgatt tcggttggaa atctccacgt taccggtgtt gtcttaggcg
    16861 aatcattgga ttatacccta acagttaaca gccggacaga tattggatca caaatagtaa
    16921 cgattagttt aggcgaagga agtgtaaaca ataattatac gattatcgca acagataccg
    16981 ctaagttgac gatcaatccg actctcttgc ttccttcgac aggtgggata ggtctactgc
    17041 cctttgtctt tttaggactg atctttattt tttctggctt cttttatttt atccatcgta
    17101 agaaaaaagc aggtgaacag cgatgaaaaa aacaaaaaat gtacgtgtgg atatatttgc
    17161 tgttctcttt tttatcctac tggtcttttt tataggttct ccgactgtgt cagctagaga
    17221 atcacctatt acatttactt tgcataatcg aatgttcgaa agcgataaga tgccaagtat
    17281 cagtcaaaac gacggaataa atatcccgga taactttcaa ggagtaaaag ggttgaacgg
    17341 cgttactttc gctatatatg atgtctcgga tgaattttac aagctgcggt cagaaggaag
    17401 tagtgtggaa gacgcacaaa gaaaactagc acaaaaaagt gatagtgaaa aaatactggc
    17461 agaaaatgtg acaaaaacag tagacgagga agagggcatt gcttctttta gtgcatcgga
    17521 caaagatgag caaggtcgtg acgctgttta ccgatttgcg gaaataaaga cttcagatta
    17581 agtaaaagaa aaatcagcac catttgtcgt tgtgcttcct gtgacagatt catctaatca
    17641 taaattgacg accatccact tgtatccaaa gagcgaacaa aaaatacctg ctgcactcac
    17701 attaacaaaa acagtagaga ataagcagac agattttgca gatggggata aagttcctta
    17761 tctcatcacc gtaacaattc ctgagaacat caacgagata ggaacctata cgatcaaaga
    17821 tacagctgat cctcagttat ggctagaacc agaaacgatc gattttttga ttggtggaga
    17881 caagattcat acatttcaca cacaaaaaac aaaacatggt tttgtcttat cagattctgg
    17941 aaaagatctt agttcgtttg ctgggaaaaa attaacgatc cgttaccaaa tgacattgaa
    18001 agaaaacagt gaaaaaacga catttgataa cgatgtacgt ttgacgactg acaatcaaac
    18061 agtagaaaca catcttgcca tccaaacagg aggcaaacaa tttgtcaaag tggatcggca
    18121 aacgaaacaa aaactagcag atgctcaatt tctagtcaaa aaaaatgacc aatacttagc
    18181 gcaagaaaac gggataaatc attgggtagc caaagatgat tcaagagcaa cgatttttac
    18241 ttccagtaaa gatggaacat tttctgtcca tggattgtct tttggaagtt acgaactagt
    18301 ggagattaaa ccgcctaaag gatatatatt gagtcaatca accattctct ttgaagttga
    18361 aaaaggcagt tatgatccgc ttcatcctat accattggaa atcatcaacg aaccaaaagc
    18421 aaatccgacg aataatggaa aaacgccagt tcagatgcag acaaatggtc catcaaatga
    18481 aaaaaatgga ggaagctttc caaaaacaag cgaagagatg cttggaggtt tctcaatttt
    18541 agggttgttg ctagtccttt caacagggac agcttggttt tataaaaaac aacaaaaagg
    18601 aaacaatagg agggaaataa aatgaaaaac atcaaaacaa aaatatggac gtttttagga
    18661 actgctatca tgctgcttcc tttcgttctc ggcctaggaa ctgcagaggt ttctaggccg
    18721 tatcacctac accagaaaat gttacggtta atttgcataa attgaaattc acttcagcac
    18781 cagaaaatca aataaacaac ggaacggaat tgacatttcc gaatagcgaa ccgttgaacg
    18841 gcgttgaatt caacgtatat gacatcactg ctacgtacta tccaagtaaa gacacagcag
    18901 ttccagcaga cgctacaccc ttcgcaagtg taacgacttc tggtgaagga ttagctaacc
    18961 tgactcttcc aggtaaatct gatgggaaag atgctgtata cgtctttgta gaaacaccaa
    19021 agcccggtgt cgaaacgtcg ccaaatatcg tgttaagctt acccttttat aacccgaatt
    19081 catcagaccc tgacaaacct ttagacacga ttcacctata tgctaaaaat gtcatcaaag
    19141 aaagcaatat caaaatccag aaagctggga acttttcagg ggtagataag ttagcagggg
    19201 cgcaattcca gatcaaaaat tcagagaatc aattcgtgac cggttttgat gaaaacactg
    19261 gtgtcgctct ctatgatcct gctgagtcag cgttgacatt cacaactgat actgaaggat
    19321 ccatcagtgt caatggatta atagacggca attatacttt agttgaaaca aaagcaccag
    19381 atggttatca attaaccaat ccacaaaaag aaactacttt tatagtaaaa aacggaaaat
    19441 tgcaacaaac aaccggtatc atccatggcg cagatgaagc caatcttggg aatccaaacg
    19501 gtgtagtcaa tcgggaaaat acaactacgg ataacacgat tactgtagaa aatgtccaaa
    19561 actacggtga tttccacttc atcaaacaag atgtgaacac gcaagaaaaa ttagccgatg
    19621 cagaattttc tattctaaga gcaaaagatc caactgttaa attaatgaaa aaaatagcaa
    19681 atcttgcctc aggagaatac ccatatgctt ggtcagatga agtcacaggt tctgactggg
    19741 aagaagtgaa attgatttct gattcagaag ggaaattttc aatcgaaggg ctgaaacaag
    19801 gggcatactg ccttcaagaa acaaaagcac cagaaggcta cgcattacct aagaatgaag
    19861 ctgcgtacac tgaatttaca gtagatgatg atccaacaac ttctgatgaa acaacgatcg
    19921 ataaccaacc taaaggaatc ttgccttcaa ctggtggtat ggggatcatc gtattcatct
    19981 tggtaggtac tgctttagtt ggaggagcag tgatctactt caaaaaacgc catcaagaaa
    20041 cagaagctta aactattgga aacaaaaatc atacgataaa taaacgatag tgattcaaat
    20101 ggggagaaag gttgtgacaa gtggtcggtc tcttggtatt cgctcaacaa acggcaaaat
    20161 aggaggaact attttgccgt ttgttgagcg aatactcagg tcaaggcgct gatttcacaa
    20221 cctcttcata tacatattag aaaataggtg gacatgatga ataaaagcag aataagaata
    20281 ctggacatct tcatggcaat cattttagtc gttgggatcg ggatcttttc ttatcctttt
    20341 gtagaagatt cactgaatga ttttcttgcc cagcaaatga tcatccatta tcaaaagcaa
    20401 gcatcgaata agaattcaga ggaaataaaa aaacagcagg aaaaaatgac aaagaaaaac
    20461 caacagttgg cagagcaaaa cgtatcacca gggataggca gtttcaacca agcagttgat
    20521 gcaaaagcat taaaagattt acctagtaat gcctttttta tggaacatat gcttggagtc
    20581 atcgaaatcc caaaaatcaa tgtcagctta cctatattcg atcagacaac ggaaatattt
    20641 ttgcaaaaag gaacgtcatt attggaagaa agttcttatc cgactggcgg gaaaaacacc
    20701 catgccgttc tttctgggca tcgtggactc ccagaagcaa aattatttac agatttgcct
    20761 aagttgaaaa aaggagacca gtttttcatc cagatcaatg gaaagacatt ggcgtatcaa
    20821 gtagaaaaaa tccaagtggt cttacctgat gaagtagatt ctttgggtat ccaaaaaggc
    20881 agagatctcg tgactttgct tacctgtact ccttatatgg tcaatacaca tcgactgctt
    20941 gtgacggggc atcgtattcc ttatcaagca aaagaggcaa aaaaagcgat ccaaggaatt
    21001 gatcaatgga aaaaatggaa attttttatt tggtttatcg gtatactact tggatcaatc
    21061 ggcttagttt ggctactcat cgcttattta gattctttgg ccatcgctaa gcgaaactat
    21121 cctttatctt tttatgtaaa gaacacaaac ggacgaccaa tcgaaggaat ggtcttttct
    21181 gtaaaaacgc tcaacggcaa acactatatt actagagaaa aagttccatt tgtgaaagct
    21241 tctgatgaat acggactagt gagattttct gatttaaaag gcaggaacta tcgcttgcaa
    21301 catgaggagc tcctgcttaa aatccatgta aaacataaac attcgaaaca gttttcaatg
    21361 aaattgaaaa aaggaagata taaactgcga aaagaaaaag aggtgtacta tttgattgag
    21421 aaagaatgaa tgaagatgtc caaaaaagca gagggaacag actaaatgaa aaaagagaga
    21481 agctgacgaa atggacgtgt aaactgctat ttttggttta ctatctggaa cgccagcttc
    21541 tattttttta tgtttcagaa gaattttatt attatagtat aacttttgaa ttagtttcca
    21601 taacatttgg agcaaggggt taaaccacga gcttgagctt cgcttaaagt ggcaggggta
    21661 tacgtaccat ttccacattt atgtgtatgg tattttgaac cggtcggtgt gacatagaca
    21721 gtttgttcat tattttgctc aggagctgcg gcttgtgcct gctgagaggc ctgttcagct
    21781 gctgcttgct gtcgcgcctg ttctgcttgt tgctgtgcga ttgcttcttg ttgcgcttgt
    21841 tctgcttgtt gtcgtgcaat ttcttcttgc tttttccgtt cttcttctgc ttcttttgct
    21901 ttgattgtgg aatcaattgc agcaagacgg cttgtcaact cttgtttgtt ttcaggtagc
    21961 gcttggatag ctgctgaagc agttgcatag ttttcttttg taggatttgc ttcagcttgt
    22021 gacaaagcag attccgcttc tgtcactttt ttttctagtg cagctttttc cgctttttgt
    22081 ttctcttctt cttttttctt ttcaatttgt tcttgttctt tcgatgaatc tgccgtactt
    22141 tcggagatcg tggtactgct gctggaagcc tgagctgaac ttgtgctttg agtagtagac
    22201 gtagtagcac cacacccact caacaaactt cctgcgacca aaaacaatgc aactaatttt
    22261 ttcactaaat ttcctcctta agtaaaaaac aaccgttttc aataaatgtc cttttcaatt
    22321 gtttacttac ttgttataat aattgtgtta tgaatagtga ttgaggaaac ttaatctaat
    22381 cccgttttga tacacgggat tttttgctat agttctgtta ttaagtatgc aataataaaa
    22441 tatgtacgtt attttattat tagattattg acatttatat aataaacgat taaatgattc
    22501 atatcaatag aatacttagg aaaaaaagag aaataataac aggtttatgc actattgacg
    22561 gtgtgacaat atgatatttg tatccgtttt ttttcttgta tgtagtatag taaagtagat
    22621 acaggaggag aaaatatgca gactttttta acaaaagttt ctcaaaagaa aattaaaatg
    22681 attcatttac tgcttgaaac agaacgttgg tgttcaatag aagaactaca aaacgaattg
    22741 aaggtatcaa gtaagtctat cttgaattat ctaacagatt tagaagaatt gttccaaaaa
    22801 tatcctgata aggtcatttt gaagaatgag aataatcggc gcttttctat ggaaaagcag
    22861 gagaacttcc caatctacat tatttatctt catttctaca gaaaatcata taattatcat
    22921 ttgattgaat tcatgtatca acatcctgag aaaaatttgg aagattatgc agacgctcaa
    22981 tatacgagtg tatccacagt ttttcgttat gctaagttat tagtaaagta ctttgaaatg
    23041 acggacgtca aagaatagta gccgccagat agaaggaaat tagcagttga aaaagctgcc
    23101 ctgcatcaag taatacgacc agccaaacgg aaacagtgtc tcatgttttt gatttggctg
    23161 gtcttattac cgcagatgca agcttttgcc acacctcttt cttgtcattt acagactcaa
    23221 ctatcaatgc tgcaagcttt cccttaatgc tgtaacacca gtaagagttg tcaagaccag
    23281 cagactgact aggtaaatac cgctcaaaaa caagattacg gcagttaaac tataatgatc
    23341 catcaagaaa ccgatgacga tagaagaaaa accaccaaca gctcgtccaa ggttcataat
    23401 gaaattattc gccgtcgcgc ggatttctgt tggatacaaa ctactaatca ctgcgccata
    23461 tccaccatac atgccattga taaagtagcc gactatcaca gcggctgcta ccaaactcca
    23521 ctggctatgg gctaacacaa gtagatagac agataaggat gaacaaatta aaaacaaaga
    23581 aaaggctagt ttaggcccca atttatccat gattatgcca aaagtcatca tccccaaaga
    23641 catgcctaaa atagtactga ccatccacaa tgaagaccca gaaaccgaaa gccctaatcg
    23701 attttgcata attgaaggca gccaattcat taacccaaaa tagccggcaa tttggacagt
    23761 taccatgata ctaaggccac atgtttgcca agcaagatgt tttgattcaa acagtctgct
    23821 aagtttggtt ttcttttcgg cagattgtac agatttgaat tcctttggtt cagtcaagcc
    23881 gcgacgaatg aacaagacca tcaacaccgg cagtacacct acgacataca acatcttcca
    23941 accaaacgtt ggaatgatca cagcagctaa aatcgcagcc aaagccgcac cgacctgcgc
    24001 accaatacca gcaaccgaag aagctcgtcc aatttgtttt tttgaaaaac tttcggaaat
    24061 caaggacata cacgccccgt attctcctcc cgctcctaca cctgcgataa agcgaaagag
    24121 ataaaccaag tagatgtttg aagcaaaata catcaataaa gaagcaatcg aaaacagaag
    24181 gaccgtttga gaaaatactt tcacacgtcc atatttatca gctatgatgc caaaaaaaat
    24241 acctccaatg agcatcccca aattagtgat cgttgaaatg aaacccgctt gcgtaccact
    24301 aatatgaaaa gaagtaatca ttgaagataa tgaaaaagct aaaaacataa tatccatatt
    24361 ctctaaagca attcccgccg atgtcgataa taataacttt cgctgatacg ttgtcatttt
    24421 tatacccctt ttcctaaaat ttccctaaat tgttaaaagt atatccaaaa aagaataaaa
    24481 aaacaagact tttttatttg aaataataca caaacaaccg atatagataa tccagcttag
    24541 ttttaataga aatgagtatt gacttggagt acacttaaag ttgtagaata aataaaatac
    24601 ataagtaaag tggcaagaaa ttaagagaaa gagtgatcag atgaatatca aacaagtcag
    24661 tgaagaaaag ggcatttcgg ccgatacatt gcgctattat gaacgaatcg ggttgattcc
    24721 accagttaat cggacaaaag gcggaatccg tgattataca gaagaagacc taaaatgggt
    24781 cgactttacg atctgtatgc gaaatgccgg attatcgatc gagtctttga ttgaatatat
    24841 tcgcctatct agcgaaggag aagcaactgt atttgagcgg cgtaagcttt tgattgaaga
    24901 aagtgaactt ttgacgaaaa aaattgctga aatgcaagaa tgtttggaac gtttacaagg
    24961 aaaaatcaag aaatatgatc gtgtgttatc tagaaataaa atggaatgta tcaagtaaaa
    25021 aaatcaagga gcatcgctat ggagttacgc ttactaaaat atttttggac aattgcagaa
    25081 gaaggaacaa tctctcaagc cgcagaagtt ctacatctta cacaaccaac cttaagccga
    25141 caactgaagg agttagaaga ggaactagga acagaactgt ttgtacgcga aaaccgcaaa
    25201 atgatcttga cagaagcagg ttattttcta aaaaagccga gcagaagaaa ttttagattt
    25261 aacgaatcaa accactcaag aattcgagaa cagaaaaaaa caattattca gcggccgatt
    25321 tacgatcggc tgtgtggaag ctgataattc gaatacattg gcactattac tagaaaagtt
    25381 gatccgtgat tatcccagcg ttcaatttca tatccacagc ggaacaagtg atgatatcac
    25441 ggagtgacta gaaaaaagcc tgttagattt agcgattttg ctagatccag tagatacaga
    25501 gaaatacgaa acgattttgt taccaagaaa ggaaaaatgg ggattgctca ttttagaaaa
    25561 ttctgtttta gcaaaaaaag acgtgataac aaaagaagac tttgcgaatg tacctctttt
    25621 gatctcaaag cgtccagaaa tacagcgaat gtttgctgac tggttaggca taaaaaagga
    25681 gcagttgctg atcacaggaa cgtacaattt gattttcaat gtatttgcgc taattgagaa
    25741 tcaggtaggt gctgctttag tcatagaagg tgctgtaagt catctttcaa agcgagtgac
    25801 attcgttccg cttgacccaa tgattgaaac gaactgcatg ctagtctgga aaaagaatcg
    25861 gattttatca cctgtagtca atgaattgat tcaccgtttc aaagaagctt ttgaacagta
    25921 ataagtatct ctaatcgaag aaatttcaat acaaaagcga gacgtatgac agtcttgctt
    25981 ttgtattttt tcatttttaa atcaaaaaaa ataaagagat ttacataact tgttaaataa
    26041 gcgcttacaa acataagaag aacggaaatg aatcagctat aataaccgtt gttctggatt
    26101 gtaatcatta caaagaaatg aagattataa ctttggaggt gttcgaaatg aaagaaaaaa
    26161 agcaaaaatt cgttcaaaaa acatgccctt tattcaatgg ttgggtatga ttctgctgat
    26221 tgtattagct ttattgacga tcattccttt tttatggatg gtttctgctt cattcaaagc
    26281 aaataatgaa gtgttcacga ttccgattca atggatccct aaaacttggc atttagagaa
    26341 ttatctggtt atttggtctc gtattccttt agtgacattt tttaagaata cagctttttt
    26401 aagcgttgtg atcacgttga ttcagttgtt tacttctagt tttgctgctt acgggttttc
    26461 taaactaaat tttaaagggc gcgatatttt atttttagca tatatcggca cgattgctgt
    26521 cccttggcag tcttatatga tcccgcagtt cattatgatg agaaaagtgg gtttaacata
    26581 tacgttgtgg tcgttggtgc tattacaagc gttcaatgct tttggtgtgt tcttgttgaa
    26641 gcaatactac agtagtatcc cagattcttt atgtgagagt gcgcggatcg atggcttatc
    26701 agagtgggga atctatcgca agatcatttt acctcttaca aaaccggcga ttgccagttt
    26761 gacgatcatc acattcgtta atacatggaa cgattatatg gggccattca tttatttgtc
    26821 ttctacggaa aataaaacaa tccagttagg gttgaaaatg tttattgggc tatttgatgc
    26881 agagtacgca ttaatcatgg ctgcctcagt tgtttctgtt cttcctgttg cttttatatt
    26941 tttagcgatg caaaaatatt ttgtagaagg gatcgcttca tcaggaatga aggaatagga
    27001 ggtgattatg aaagagcagc gttttgacaa aaatgtttat atggaattct tttattggtt
    27061 gtatcaatca ttggcaagta gcctttgttt ttggtgtgtc aatatcttgt atatagcagc
    27121 tgcgttcctt ttgtcgatag atggaaggaa tgtcttttcc tttatttttt ctttactttt
    27181 tattggtcca ggttgcatcg tgatgatagg tatgacagaa gaattagcaa aagaaaaaag
    27241 tttttcacca gtacgtttgt tcataaagac gtttcgccaa ttttggctaa agggattttt
    27301 ttattggcta tttgcttgga tagttagtgt gataatgatt tttgattgtt tcttttttat
    27361 acgtttttct tatggaaaat ggttgattcc gttgtttgtt ttacttgctt gtttatcagt
    27421 ttcctttagc atcaactact ggtattttca ggtgagaaat ccagcgtcga aaccaaatca
    27481 agttctacgg atagcgttct actatacgtt gaaaaaatgg tatgtgagtt tactagattt
    27541 tttactattg acaagtttgt ttctcttctt tttcgtaaag ccccaatggt gtattctact
    27601 aggtccttct atcgtatttg gtttgattta cttcaacaat cgtaaattga tgagaactat
    27661 ggatctgtag actttataaa ttgaaacttt caattaagaa tgacagtttt tatgtaaaaa
    27721 ctgtcattct ttttcatttt ttgaaacata tggctaaaca aatgaaataa aacgtgctat
    27781 acttttgaat gaaacaggtt tagaaactgt atcaattatt tgtgattatt tctaactaat
    27841 aattaaaaat aaagcataaa aaggacgatg ttcaatggac gaaaaaatga aacaaggttc
    27901 gaaatctgta gtagaaagtt tgattaatca tcatgttgat tatgtattcg gtataccagg
    27961 tgcaaaaatc gatggtgtat ttaatgaatt agaggatcaa ggtcctgaat taatcgtgac
    28021 tcgtcacgaa caaaatgctg catttatggc acaagcaatc ggacgtatta caggagagcc
    28081 aggagtagtt atcgcaacaa gtggtcctgg tgctagtaac ttagctacag gtttggtaac
    28141 agcgacagca gaaggtgacc cagttttagc aattgccgga caagtaaaac gaagcgatct
    28201 attgaagttg acccatcaaa gcatggataa tgcagcactg ttccagccaa tcacaaaata
    28261 cagtgcagaa atccaagatc cagaaacaat ttcagaagtg attgccaatg cttatcgtat
    28321 ggctaagagt tcaaaaaaag gcgcgagctt tatcagtatc ccgcaagatg tagtggatgc
    28381 acctgtccaa gggaatgtca tcaagccatt gagcgatcct aaattaggtt ctgcttctgc
    28441 agatgatatc cgttacctag ctgaacgcat tagagaagca aaactaccgg tactattagt
    28501 aggtatgcga ggatcaagtg aaaaagaaac gttagccatc aggcaattag ttggaaagac
    28561 agcattgcct gttgtagaga cattccaagc agctggagtg atctcacgtg aattagaagc
    28621 gcatttcttt ggtcgtgtgg gtttatttag aaaccaacca ggagatatgc ttttgaaacg
    28681 aagtgatcta gttattgcta ttggctatga tccaatcgaa tatgaagcaa gaaactggaa
    28741 tgcggaaaaa gatgcgcgga tcattgtgat cgatgaagcg ccagctgaaa tcgatccttt
    28801 tatgcagcct gaaagagaat tgatcggtga tatctcagcc actcttgatt tattgacagg
    28861 ttcattagag cctcaacaag tgtcagaaga tgcaaaagaa tatttagcat ctcttcaagc
    28921 agaattaacg gagcgggaca ttgttcaatc aaaaggagaa gcaggtatct tgcatccttt
    28981 agaagttatt aacacgcttc agtcaaaagt aacagatgat atgactgtta ccgtagatgt
    29041 aggtagtcat tatatttgga tggcacgcca ctttagaagt tatgaacctc gtcatttgtt
    29101 attcagtaat ggtatgcaaa cgcttggtgt tgcattgcca tgggcgattt ctgctgcatt
    29161 ggtgcgtcca aatacacaaa tcgtatcagt ttccggcgat gggggatttt tattctctgc
    29221 ccaggattta gaaacggcgg tacgtaaaaa attgaatatc gttcatttga tttggaatga
    29281 tggacactac aatatggtag agttccaaga aaaaatgaaa tatcagcggg cgtcaggtgt
    29341 agactttggt ccagttgatt ttgtgaaata tgcagaagct tttggcgcta aaggaatccg
    29401 agctacaagt gtagaggaat tagaaaaagc tttagaagaa ggatttgcga cagaaggacc
    29461 cgtaattatt gatattccga ttgattaccg tgataatgag aaattgggag aaacaatctt
    29521 accagatcaa ttctattaag gaagtgtcga catgactgaa aaaatcttat accagcacgg
    29581 gacattagga gctttgatgg ctggcttgat ggatggaaca gaaacgattg ctcatatatt
    29641 agaaaaagga actctgggat tgggaacatt gcatgggctt gatggtgaag tcatcttttt
    29701 agatggcgta gcttatcaag gaagatcaga tggctcagtt gcccaattag atggaagtga
    29761 acttaccccc tatgcagcaa ttacagattt tacgccagat actagttttt ctgtctcaaa
    29821 aactgcagat ggagaacaat tgaaaaaaga catattagta agagaagccg gggaaaacct
    29881 atttttggca gtgaagataa ctggattatt caaaaatatg cacatccgta tcatgccgaa
    29941 gcaagaaaaa ccttacagaa gactagcaaa aatttcagag tctcaaccag aattccaaca
    30001 aagcaatgtc caaggaacat tagtcgggtt ctttacgcct gaattattcc aaggagttgc
    30061 tgcagcggga tttcacctgc attttatcga tgatacacat acatttggcg gacatgtaat
    30121 ggattttgaa gtggctgaag gaaaagttga gattagccgc atctcgtccc ttgtacagca
    30181 ttttccagtt gatgatccga cttttgttca cgaaacgatt gattatgctg atttagcagc
    30241 agaaatccaa caagcagaat agaaaaagac agcgagatgc gttcaaggtg attaacctga
    30301 cgtatctcgt ttttttgagg agaaaaccta gcgtttacaa aaaaactgag ctataatctt
    30361 ctccatagat caaaaaggag cggtttttat catgtggaca gaaaaacaga aaaaagatgc
    30421 atacgaaatt ttattattac agcaacaagg attattagaa gcagaagata actggttagc
    30481 aaatttagca aattcatctg cattgttgaa tgagactttg cctgagactg tctttgcagg
    30541 atattattta ttcgatggta atgaattgat tttaggaccg ttccaagggc gagtttcttg
    30601 cacacgtatc aagatgggaa aaggagtttg tggagaatca gctgaaaaac aagaaacatt
    30661 gatcgttgat gatgtcaaaa cccatgcaaa ttacatttcc tgcgattcag ccgcacaatc
    30721 agaaatcgta gtgccaatgg taaaagaagg taatttaatc ggtgttttag atatcgattg
    30781 cggagtaacg aaagggtatg atgaaatcga tcaagcattt ctagaaaaat atgtagatct
    30841 tttattagca aattttaata taaatgcttt ttcatttatt aataactaaa atcgtctatt
    30901 gaaacaaaaa agaagagaaa tcaagaataa aaagagccgg aaagacagtg ggcatttctg
    30961 tttttcggtt tttttatttt tttataaaat cacaagtgtt attgattttc ataatcatat
    31021 tttaatgtta ttatcatttt aaataatgaa aaaacattaa ggatggatga aatatgaata
    31081 acgaaactat cattttagga aaaaaatata tttgccaacc tattggcttg aaacaaaaag
    31141 tgattggaga agtaatcagt aaattagaaa attgtgttgt gatctgcgta gacgaatatc
    31201 atgacgtcga tcgcaatgaa atattagaaa aatgcggaaa agtagtggca aaatatactc
    31261 acgtttatga gttggaaaca acagaatatc tatataacta tagcaacaaa tatgaacata
    31321 ctttagtttc ataaagattt aaataaagtg ccttcaaaag cgagaagacc aagcttttga
    31381 aggcacttta tttagttggc agtgattgtt catgattttt gatttattca aaaggttcgc
    31441 ctagagaatc tgtctctgta acgaggcctg gtggagaaac tcgataaaaa cctatactgc
    31501 cagaactgtc ctattttcgg atagacaaac tagtagtttt aaaaagatca tccgatccaa
    31561 tcatttcaaa aaatgcaaaa ctgatatcag gatcatttag ctcaggcttg ttatcgtaaa
    31621 gcatttgtaa aggttgcatt tagttaggag taaacgcgaa actatcatca ttatttgctg
    31681 aagaagatga agaagctaat tcagagtttg tttgaaataa aggagacgtg ctgacagttt
    31741 ctttaccctg ttttttgcag aggtagaaac ttttatatcg gaagtttcta ccggagaatt
    31801 tttctcattt gtagaaattg ttgaatcgat actattcgaa atttgcgtat ctgaaggtat
    31861 gttctttgat gcagaagtcc cacaagcagt aagtaacaat aaatttgata aactgataaa
    31921 cagaattctt ttcattatgt acacactcct tatagtatcg tttagcatac acctatgctc
    31981 agtattaggc aaaatcaatg caaaactatc aagtctttta tagtatctat tagtcttagt
    32041 aatacatata tggagagggt gatatcccag ttcaaaccag atacattggt taccatctgt
    32101 attaacgatt atgcctctaa acgctttttt tatgaaaaaa tttataagtg aaaacgtagg
    32161 tatgatatta tctagaggta atttttttgg gtatttaaat agttgctagg aggatagctt
    32221 ttggattttt acagtaattt tatcttaata atagcaatat tattacttct aaatatttgg
    32281 ttttttgata agagtagaaa tgcagggata ggttttagaa ccaaacgaag tacgtcttct
    32341 gaaaaaaagt gggtatattc acagactatt ttttacggag gggttatttc aatcagttta
    32401 ctttcttcaa cactttattc ttttaatgtt atagacgttt ccatgtcaaa ttttatatct
    32461 attattggaa tccttatttc tgcaattatt acacaactac ttcttgtgtt tgaagagaag
    32521 tcaaaaaata attaaagcaa ttatgccttt tagtacagga attattactt cttacaaatg
    32581 tatagcgaat gtgaagcctg ctgttttaat tgttctagaa aaacttttga gtgaacaatt
    32641 attttatgtt aggatgaatt aatttctcta gagtttata
//
LOCUS       DBBGSZ010000029        32534 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.029, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000029 DBBGSZ010000000
VERSION     DBBGSZ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.029"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            132..506
                     /locus_tag="ACIZE5_001859"
     CDS             132..506
                     /locus_tag="ACIZE5_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HGC6108984.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(620..1249)
                     /locus_tag="ACIZE5_001860"
     CDS             complement(620..1249)
                     /locus_tag="ACIZE5_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HGC6108985.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1383..1455)
                     /locus_tag="ACIZE5_001861"
     tRNA            complement(1383..1455)
                     /locus_tag="ACIZE5_001861"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1420..1422),aa:Thr,seq:ggt)
     gene            1669..1742
                     /locus_tag="ACIZE5_001862"
     tRNA            1669..1742
                     /locus_tag="ACIZE5_001862"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1703..1705,aa:Asn,seq:gtt)
     gene            complement(1880..2044)
                     /locus_tag="ACIZE5_001863"
     CDS             complement(1880..2044)
                     /locus_tag="ACIZE5_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6108986.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2339..3667
                     /locus_tag="ACIZE5_001864"
     CDS             2339..3667
                     /locus_tag="ACIZE5_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HGC6108987.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3869..4702
                     /locus_tag="ACIZE5_001865"
     CDS             3869..4702
                     /locus_tag="ACIZE5_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HGC6108988.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4718..5455
                     /locus_tag="ACIZE5_001866"
     CDS             4718..5455
                     /locus_tag="ACIZE5_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HGC6108989.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5610..6578)
                     /locus_tag="ACIZE5_001867"
     CDS             complement(5610..6578)
                     /locus_tag="ACIZE5_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HGC6108990.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6810..7643
                     /locus_tag="ACIZE5_001868"
     CDS             6810..7643
                     /locus_tag="ACIZE5_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HGC6108991.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7677..8516
                     /locus_tag="ACIZE5_001869"
     CDS             7677..8516
                     /locus_tag="ACIZE5_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC6108992.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8542..9102
                     /locus_tag="ACIZE5_001870"
     CDS             8542..9102
                     /locus_tag="ACIZE5_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC6108993.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9301..11022
                     /locus_tag="ACIZE5_001871"
     CDS             9301..11022
                     /locus_tag="ACIZE5_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HGC6108994.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11187..12329
                     /locus_tag="ACIZE5_001872"
     CDS             11187..12329
                     /locus_tag="ACIZE5_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGC6108995.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12345..13556
                     /gene="thiI"
                     /locus_tag="ACIZE5_001873"
     CDS             12345..13556
                     /gene="thiI"
                     /locus_tag="ACIZE5_001873"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HGC6108996.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14129..14776
                     /locus_tag="ACIZE5_001874"
     CDS             14129..14776
                     /locus_tag="ACIZE5_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HGC6108997.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14905..15121
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15169..17814
                     /locus_tag="ACIZE5_001875"
     CDS             15169..17814
                     /locus_tag="ACIZE5_001875"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HGC6108998.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18124..19437
                     /locus_tag="ACIZE5_001876"
     CDS             18124..19437
                     /locus_tag="ACIZE5_001876"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGC6108999.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19427..20080
                     /locus_tag="ACIZE5_001877"
     CDS             19427..20080
                     /locus_tag="ACIZE5_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC6109000.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20135..20827
                     /gene="radC"
                     /locus_tag="ACIZE5_001878"
     CDS             20135..20827
                     /gene="radC"
                     /locus_tag="ACIZE5_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HGC6109001.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20977..21177
                     /locus_tag="ACIZE5_001879"
     CDS             20977..21177
                     /locus_tag="ACIZE5_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HGC6109002.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(21431..23110)
                     /locus_tag="ACIZE5_001880"
     CDS             complement(21431..23110)
                     /locus_tag="ACIZE5_001880"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGC6109003.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(23112..23324)
                     /locus_tag="ACIZE5_001881"
     CDS             complement(23112..23324)
                     /locus_tag="ACIZE5_001881"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit epsilon"
                     /protein_id="HGC6109004.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            23717..25447
                     /gene="efrA"
                     /locus_tag="ACIZE5_001882"
     CDS             23717..25447
                     /gene="efrA"
                     /locus_tag="ACIZE5_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HGC6109005.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            25444..27204
                     /gene="efrB"
                     /locus_tag="ACIZE5_001883"
     CDS             25444..27204
                     /gene="efrB"
                     /locus_tag="ACIZE5_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HGC6109006.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            27299..27496
                     /locus_tag="ACIZE5_001884"
     CDS             27299..27496
                     /locus_tag="ACIZE5_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109007.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            27649..28134
                     /locus_tag="ACIZE5_001885"
     CDS             27649..28134
                     /locus_tag="ACIZE5_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HGC6109008.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(28238..28831)
                     /gene="clpP"
                     /locus_tag="ACIZE5_001886"
     CDS             complement(28238..28831)
                     /gene="clpP"
                     /locus_tag="ACIZE5_001886"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HGC6109009.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            29011..29538
                     /locus_tag="ACIZE5_001887"
     CDS             29011..29538
                     /locus_tag="ACIZE5_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109010.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            29629..30366
                     /locus_tag="ACIZE5_001888"
     CDS             29629..30366
                     /locus_tag="ACIZE5_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HGC6109011.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            30370..31287
                     /gene="miaA"
                     /locus_tag="ACIZE5_001889"
     CDS             30370..31287
                     /gene="miaA"
                     /locus_tag="ACIZE5_001889"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HGC6109012.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            31289..32518
                     /gene="hflX"
                     /locus_tag="ACIZE5_001890"
     CDS             31289..32518
                     /gene="hflX"
                     /locus_tag="ACIZE5_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HGC6109013.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT        10772 a         5522 c         6874 g         9366 t
ORIGIN      
        1 tctacactct gagatgtaag aaatatcata agatatttct tacatctttt tgttttgagc
       61 aggactttag ataattttat taatatatgc tagcatgctt ttgtaagaaa aagaaagagg
      121 gcgtattagt tatgtatctt aaaattacgg aacaagcaca agaaagatta caaaaatata
      181 ttgatgaagg cgcaacagtt atattggatt tagatgatgg cgttggggaa tattctaaaa
      241 tgggtgtttg ctctttagat actagttttc gtttacttct tcttgataaa gaacagagaa
      301 aaaatgatta taaactccaa ttagatagtg atattgggga tgtttatata aaagattatt
      361 caaaaatgta catggatgaa catatgaccc tttctttaga tccacgtcta ggtgtattta
      421 ctcttgaaag cccaagtggt tctttagaca gtcatgttca attagtagat ctacgaccag
      481 aaaaattctc tggaataaaa caataacttt ctctctattg tccataaaac tagtctcaat
      541 caagctgtat tgaaaaaaca agacaacatt cttaccatgg taaataaaaa gacgacacat
      601 tttgtcgtct ttttttaaat taactatttt cgataaaaga tcgcatagct tgtgccatta
      661 tttctggctt ttctctattc aattcatgtt ttccgttttt aataaagagt agccggccat
      721 tcgttgaaag tttatataaa cgttttgctg ctggtttatt cgcatgatct ttggtaccgc
      781 ataaaatcaa tttaggaagt cgtgatgtac gaagctgttt tttgcagtct aatgtttcaa
      841 gtgaacgaag tagggtaagg gtttgttttt tagatagacc taatttttca aatatcttag
      901 aaggtacgca gtaaaaataa atattctgga aagtaagcaa taagcgatta ggagactcaa
      961 attgtggagc gactaaaaca acctttttta aatatggaga aggagttgca agatagttta
     1021 aagcaataac agcgcctaaa gataatccac ataaaataaa aggttccttt atctgattca
     1081 attgtacttc gatgtatttg gttaagtcgt ctaaagtagc agtgtctgtg ctgtttaaat
     1141 gattgaacaa tgaaagactt ttgcaagaat aactattggg tagataagag attacatctt
     1201 tccatgattg ttcgtcttgg cctagaccat gcaaaaaaac aattttcata ttgctctcct
     1261 ttttatagtt atcatataga ctttctttgt actattaaaa tataaacatt catttcttac
     1321 gtcataaaat aaaaaaacag cgcagacaca ttgttaaacc aacatgttgc actgtttaag
     1381 gaagccactt gccgggcttg aaccggcgac ctcttcctta ccatggaagc gctctaccag
     1441 ctgagctaaa gcggcattat cattaataca aataatagga taacgaatat taatgtattt
     1501 gtcaacagaa ttttttcgaa aaaatgtgtt tctctaatag gaaaacagat tttagaaaaa
     1561 ataaaaataa caaaaaatgc gaacggtttc tttgataata taataaaaaa attcaaaaaa
     1621 agtattgcgt tatttagaag aaattgatat tatattcatg tacttgattc cggcatagct
     1681 cagttggtag tagcgcatga ctgttaatca tgatgtcgta ggttcgagtc ctactgccgg
     1741 agtaaataaa gcttatgcaa agaaaaagaa atccaatcac ttgggtttct ttttctttta
     1801 ttattatgat gaatcaagct ttctgttttt gtcacgtatg ttgtaatctt tacgaaagag
     1861 tagagttggc tactcataat caaccatact tcccatcatc gctaaatacg aaataaatca
     1921 gcattcctac accaatcaaa gcacaagctg caccaagaaa agggatgaca ttcccaaagt
     1981 tatctgtatt cataagtatg ccaccaccca caaacaaaaa gccgccagca atcaggtttt
     2041 tcattttatt catctccttt cttacgttat agtatttcct tctttcaatg agtattttga
     2101 aagctatctt attgtatgat gttcttctag gcctcttctt tattatacag gccattttcg
     2161 ttatctcata gaaatattcc tttttatctg aaaactattg tataccgtat gacatttttc
     2221 ttcatgaagt tgtaagtata ttctcattca aatgaaaatt tcatcataga agagattgta
     2281 tttctaaatt cttaagagta aaatacgaag tataacttgg atttggaagg atgattggat
     2341 gaaagctatt acgcctgata tgacaacaaa atttaacaaa cagtttcaag caaatatcaa
     2401 acagcaggca ttgcagcggg cagttgtgaa gaacggaatt actgcttctg ctgaaaatgt
     2461 ttcagcacat gtggagaata caccggtatt ttctatagat ttggctacgg ggaaagtggc
     2521 taatcaaatg caatcggggc gttgctggat gtttgctgca ctgaacacat tccgtcataa
     2581 gatgctgaat caattccatt taaaagagtt tgaattatca caaaattaca cttttttctg
     2641 ggataaatat gaaaaggcaa attatttcta tgaaaacatc attgcaacag gaaaagaggc
     2701 aatcgatagc cggaaagtag ctttcttact cgctactcct caacaagatg gcggccaatg
     2761 ggatatgatc gtttcattat tccaaaaata tggcgttgtg cctaaatcgg tgatgccgga
     2821 aagtgcgaat agttcaaatt ctcgagattt gaataactac ttgaacaaat tactgcgtaa
     2881 agatgcagta gtgttacgga aaatggttgc tcaaggagaa acattagacg ctattgaaga
     2941 aaagaaagaa gaaatgctag aaagcattta taacttctta gctatctcat taggaacacc
     3001 tccaaaagaa ttcgattttg agtaccgcga tgaagaaaag aactatcatc ttgaccgagg
     3061 actgacacca caaatttttt atgataaata catcggtgta aaattagatg attatgttag
     3121 cgtgatcaat gcaccaacaa aagacaaacc attcaatcgt tcttatacag tagagatgct
     3181 aggaaatgtc gttggcggga aagaagtcaa atatctgaat gttgatatgg aaactttcaa
     3241 aaaattagcg attgctcagc ttgaagaagg agaatctgtt tggtttggtt gtgatgtagg
     3301 tcaatcttct actagaacta gtggcatcat ggccttagat gcttattcaa tggatgatct
     3361 atttgatacg gattttacaa tgactaaagc tgaacgttta gattttggag aaagtctgat
     3421 gacccatgcg atggtattga ccggtgttga cttagtagac gggcaatcaa caaaatggaa
     3481 agtcgaaaat agctggggcg aaaaagttgg aaagaatggc ttctttgtta tgagtgatgc
     3541 ctggatggac gaatatacgt accaaatcgt tgtaagaaaa gatttattga cgaaagagca
     3601 attaaatgcg ttcaatgaag aaccaattgt tctatctccg tgggatccaa tgggtgcttt
     3661 agcatagacg agtatttcaa tgaagagtat gtagtaaaga taaaaagagc tggcttaagc
     3721 cagctctttt tatctttaaa gtccattccc tgttttttat ggtccctgtg ctataattct
     3781 aaataaagga taaggattgg aaataatcct tttatcatta aaaatatgat gacgaagtag
     3841 aataaaattg ggagtagggg ggaaagtcat ggatatccaa actgttttat ctgatctgaa
     3901 attaaatggt aaagtgattc cagttgttgg tggcgatgtt aatcagacct atcgtataaa
     3961 aaccgaacat cgtgcttatt ttttaaaaat ccatccgaat gtaaaaaaag gattttttga
     4021 agcagaagta gacggattaa aagaactgtc agcattcgta cgtgtaccgg atacgtatat
     4081 gctaggtgaa acaagtgaag gcgcttattt gttaatggaa tggatcgagc cgggaaaagg
     4141 ggatcaacga gatcttgctg cagctttagc taatctccat cagcaaacag cgccacaatt
     4201 tggttttcgt aaagataact atttgggtac acttgttcag aaaaattctt ttgaagaaga
     4261 ttggtggact tttttcttta aagatcggct tgaatcccag atttctttgg cagaagaaac
     4321 gaatcgatgg aatgtacagc gtcaagaaaa gtatctgcga tttaaagaac gtgtattgaa
     4381 atcggttgaa ccaaaaaaga tcactccacg cctcttgcac ggagacctgt ggagtggtaa
     4441 tgtgttcttt gaccagcaag ggcatccagt ttttgtcgac ccagctgttt cttatgggaa
     4501 tcgggaacaa gatattgcaa tgagccagtt attcggtggt ttccgaccgg aatttttaga
     4561 tgcttatcaa actatatttc cattagaaaa gggatggaaa gaccgactgc cgatttacca
     4621 gttatattat cttttggcac atttgaatat gtttggagaa agttacggtt cccaagtaga
     4681 tcaattacta gaaaattttt aagaggaggg cgtgtttttg gcaaaaaaat ataccaaaaa
     4741 gcatgaagtt tcatattatg agtgtgacat caaccaaacg atgacatttc cttcgatgtt
     4801 aggagtagtt atcaaaacgt ctgaagatca aagcgaccag ttgggaagag gcagtgaatt
     4861 cgtcaatagc tttggactta cttgggtcat cacgaattat tccatggaga ttaatcgtct
     4921 ccctagagtc ggtgaagtaa tctcagtaac gactcaagcc atggagtaca ataagttttt
     4981 ctgttatcgg aacttctgga tccatgatga agatgggaaa gaattagtca aaatagaatc
     5041 tgttttcgta ttgatggatt ttgtgaatcg aaaaatgagc agtgttaatg aagagatcat
     5101 tgctcctttt gagagtgaga agatcaagaa aatcaagcgt caggaaaaaa ttgaaaagat
     5161 tgattcgggc ttcatgttgc catatcgtgt tcgtttttat gatatcgata gtaatcagca
     5221 tgttaataat gcgatgtatt ttaattggat cattgacgta ttaggatatg actttttgac
     5281 tacgcatgtt ccagaaaaag taattattcg atttgataaa gaagtagagt acgggaatga
     5341 gatcgaaagc cattttgaac aaatccctat cgaaaatggt gtcaaaacaa aacatgaaat
     5401 ccgaatgcaa gaacagctgt attgtgaagc aaatattata tggaaaaata aataaaaaag
     5461 aggttgtgac agaagggggc aacttcaaga aataagaaga aatttacgaa aattgtttct
     5521 caaatttttg taaattttcg acttagtttt cgaagaagct atttttgtca cagcctctct
     5581 ttttaagttt agctattaga taatgatgtt tagttttgga taaacgaaat caattcttca
     5641 cccgacaaac catagtttac agcaatcaat agttttaaac gtgctttttg actattaata
     5701 ctgttacaga aaataatccc cattttttct agttcttttc ccccgccttc ataatcataa
     5761 acaggctctg cgattccatt gaaacaacga gaaacaagta ctacagggat tttttggaca
     5821 agaagctttt ccaaagcagc taaggcttgt ggagggagat tccccgcacc taaagcttcg
     5881 attaccaaac cgtctacttt cgtatgggcg atggcttcca ataagtcccc ttgcatccca
     5941 gcatatgctt taacgatcgg gatagtccca tctacagcgg aaatgtccag tcgctttgtt
     6001 tctaaaagtt cctgcaagaa taaaattcga ttcttagtta ctaagccgat gggacccaat
     6061 gtaggtgttc ggaaagtagc aacatttgtg gtatgggtct ttgtcacgta gcgtgcagaa
     6121 tggatctcat cgttcatgac caccaaaacc cccttatcta gcgcttcttc acaacttgcg
     6181 acacgaatcg cactttcaaa attataaagg ccgtcacttc caagttcatt acttgaacgc
     6241 attgccccag tcaaaacaat tggtaatttg ttgccaatcg ttgtatcaag aaaaaaagca
     6301 gtttcttcta atgtatctgt accgtgtgtg atcaccactc cggatatacc tgatgcataa
     6361 gcggacaaga tacgttcttt taataccaac atgtgagaag gcatgatgtg tggtgaggga
     6421 agattgaaga tatcttcaac taataattct acatgcttgg ggattgtgat ttctgcatct
     6481 aataatgggt ttgccacatc aggactaaca ccgcccgtga gcatgttttc tttcatggcg
     6541 atcgttccgc cggtgtgtag tacaagtatt tttttcattt tacagacttc cttacgaata
     6601 attttgcata gccgttaaat cttattgtat actatataaa agagttttgc tatcagtgaa
     6661 gaataacgaa tagcctaact tatcataaaa aagctgacct tattaaaatg gaaaagactc
     6721 aaccttgacc tcctaataca atggagtatc tggttgagtt tcttttacaa gaaagcagcc
     6781 aaggaaatca atcacgaagg tggccggaaa tgatcagaat cggattaaca tcgtttaaag
     6841 aacatgacaa attaactggt aaaaagaata acactcttta tgaatatgca gggtttctac
     6901 ccttagtgga attagatact gcctattatg gaattccccg aaagtcctca gttgagaatt
     6961 ggataagtga agtacctgaa tcatttcgct ttgtagtcaa agtctatcaa ggaatcagcg
     7021 gtcaaggaga ctggaagcct tattatcaga ccgaagaaga gatgattgcg cattttttag
     7081 atgttatgtc gccaatggta gatgctggaa agatgttttg ctttttagtc caattcccct
     7141 catcattcaa atgtacgaaa gaaaatgtcc agtacttgcg caaacttaga aagtggtttg
     7201 agggttatcc tgtttctata gaattgcggg attattcttg gtacagcgat gaatttcttg
     7261 aacgtacaag aaactttatg tctagagccg ctttttcttt agccatcatc gatgagccac
     7321 agttgctgaa tacaacgatt ccttttgatc catttgtcac caatccgaac tttgctcttt
     7381 ttcgattcca tggtaggaat gcgcaaggat ggcaagcaaa tgataaagag tggcgtaaaa
     7441 aaagaacgtt atatcgttat tcagaaaaag aactgcaaga actagcacat gaagtcaaag
     7501 tagttgattc taagacaaaa gaggtaggtg tgatttttaa taataattct ggtggtgatg
     7561 cggctgaaaa tgcattagca ctgcaaaaaa tattaaatat caagccagat ggactcaatc
     7621 caacccaaat ggatctgttt taagggctta ttttattcaa gaaaggggcg aagtctatga
     7681 tcaaagctat tttttttgat attgacggaa cattggtcac caatcgttca aaagcgttgg
     7741 aatcaacaaa acaagcaatt gaatatgctc ggaaaaacgg cattttatgc ggtgtagcaa
     7801 cggggcgcag cccagtaaag atcaaagaaa tcattgatga attggaatta gatatgtatg
     7861 tcgtgtataa tggtcaactg gtttttactg cagatcgcac gattatcgac cacccttttg
     7921 aacaaaaagt attggaacat attgttgaat ttgcagatga gaaccatcga caaatcgttt
     7981 ttggtgcgag aaatcggtta gatggatcaa cgacgatgct attaggacaa tcgattttta
     8041 tcaagcgact agtcagcttt ttaccgcgta aattcccggt acgtctgatg aaaaaaatcc
     8101 tccaggtttt tagccctcac cgacaaaagg atcgttatga aacgttagag atattaaaag
     8161 aaccaattta tcaatgtata ttgctcagtc cggagtcaga acagaaaaag ttagaacatc
     8221 gctttcccga gtgtacgttt cagcgttcaa atacgtatac tgtagatatc atcccaaaag
     8281 gtggttcaaa attactaggc atccaagctt tcgcaaatgc tgtcgaaatt gaaatggaag
     8341 aaattatggc attcggcgat cattacaatg atatcgagat gctgaaaggt gtaggaattg
     8401 gagtggccat ggggaatgct cagatcgaag taaaacatgc tgcagacttt gtgactcaat
     8461 caaatgaaga agatgggata tacgaaggac tgaaacactt cggtctgatt tattagtcaa
     8521 tgaaagaagg aaaaaatcag tatggaagca gagacacctt ttcaaaaagt agaaacattc
     8581 cacaaaactt ttgatccaag aagaccagag atacccacgg cttttacaga aaatgaagct
     8641 catacacgtg ctgcgttcaa aatagaagaa cttgttgaat ttgttgcagc tacttcacct
     8701 aataaagaac aactgcatga agctgttatg ctgctgcacg aagcattaga taaagcagaa
     8761 gaaaaaatac ttggtaaaac acagtgggga agtgatccgc tggttgaaca agtagatgca
     8821 ctgacagata tcctttactt tacttatggt tctttttcat tactaggaat agtgcctgat
     8881 cgaatattcg aaatcgtcca tcaggcaaat atggggaaat tatttccaga tggaaaacct
     8941 cattatgacc ctgtaacaaa taaagtgttg aaacctgaaa actggcagat ggaatatgct
     9001 ccagaaccta aaatcgcggc agaaatccaa cgtcagattc aagaagcgat tgctaagaag
     9061 aaatccgctg atataggcat gtgcacaaat gaaaaagagt gatcagagtt tcactatttt
     9121 tgttatcttt atacgatgga aaaacaaaag attttcgttt aagttagtga atgcatgaaa
     9181 atagtatgct ataatctaga atagatgtct tttgcacgag agacgtatta tttggattta
     9241 tgccaagcag aacgccatct gttgcataaa agatgcatac tgaaaacgga ggaaccataa
     9301 atgggaaata atgttatcat cggaatcgtc attgcaatca ttatagtcgc cattgtcgtc
     9361 tttttggtta gttacttgat gaagaaaaaa aaccaagatc gattggatgc cttagaaaaa
     9421 cgcaaggaag aattatttga cttgccagtg attgaagaag tcgatgatgt taaaaaaatg
     9481 catctggttg ggcaaagcca aaataccttt cgtgaatgga gtcaaaaatg gaatgacata
     9541 tctacttcct cgttcgctga actagaaagt caaattttcg aagtggaaaa cctcaatgaa
     9601 agttttcggt tcttaaaagg aaaaaaagca gttgttgaag cagaagctac aatggaccaa
     9661 atggagaaac aagtgacgga aatccgtgaa ggtctaaagg aattgcggga aacggaagaa
     9721 cgcaactcac tagctgttca gcaggcactt gacgtctatg aagaactgaa agaaaaagtc
     9781 agagaagacg agcatgaata cggaccagct ctttttgaat tgcaaaaaca gatcaaagtg
     9841 atcgaaaaag aatttacgca gtttgtgact ttaaacactt ctggagaccc tgttgaagcc
     9901 cgcgaggttt tggataaagc agaaaaacat acgtatgaag tggaagctct gatgaaaaaa
     9961 attccaccgc tgtatgagga gctccatacc actttccctg aacaacttga agaaatcagt
    10021 gatacttacg agaaattgat ggaagaacaa tatgtattcc cagaagaaga tcttgctgaa
    10081 gatatcgcaa aagtaagtcg aagaattgaa aattcattag ccaatcttga aaaaacagaa
    10141 gttgaaacgg tcgaatttga aaaccgtgaa acagctgatt tgattgattc gttatatgat
    10201 atcttagaac gggaaatgga agctcagaga tatgtaaaaa ctaaccaatc aacgattgca
    10261 gagtatatca aacatacaac aaagaataac cgtcaattat tgattgagct ggatcacaca
    10321 tctcaaagct atacattgaa ccacaatgaa attggccgtg tacgaggttt ccaaaccgaa
    10381 gtggaagaaa tggaacgtca aaatgaacag atgattccac agatccgtca acacgaaatt
    10441 ccttattcag aagtgcgcac gttctataaa acagtcttca aagtcttaga agatatcgaa
    10501 aagcaacaag tagagatcga cgactcatta catgaattga gaaaaggcga aaaagaagcg
    10561 caagaaaaga tcgatacatt cgaattcaaa ttgcgcagtt tgaaacgttt tgtagaaaaa
    10621 caacgtttgc ctggcttgcc gaatgattac ctagaattct tttttgttgc tactgaccgt
    10681 attgaagaac taagtgttgt cttgaataaa attcgagtaa acatggaaga ggtcaatcgt
    10741 ttagttgctc tatgtgaaga agatctagaa ttattagata agaagacaca tgatttagta
    10801 gatgcagcag cattaacgga gcaaatgctc caatatgcaa atcgttatcg tcatacacac
    10861 gaagaagtga gagaagcaat tgataaaagc tactatttat tcaataaaga atatcactat
    10921 caagaagcat tagacgaaat cggtacagca ttagagcgag tagaacctgg tgctttcaaa
    10981 cgcatcgaag atttttattt taatcatcca gacttagtat aaagcaaaaa agttagtaaa
    11041 ccagcaagag caagacggat tattgtcttg ttcttgtctt tttttgtata tttgaaaatt
    11101 gaaacaagtg aaaatttcac ctgctcttga aagcaccttg gacaaccgtt ataatagaaa
    11161 agaatttcaa aaaagagggg tttcttatga tatattttga taacagtgca acaaccccaa
    11221 tctttccgca aagcttagat gcatatgtaa aaaccagtca gcggattatt gggaatccat
    11281 caagcttgca tgatttaggc aatcaagcta accggttgtt gcagcaagca agaaagcaga
    11341 tcgctgattt gatccatgta gaaccagaag aaatctattt tacttcaggc ggaacagaag
    11401 gagataactg ggtattaaaa ggaacgatga tcgaaaaaag agaatatggg aatcatatga
    11461 tcatttcagg agtcgaacat ccggccgtca gcgagacagc agaacaatta aaagaattag
    11521 gaatcgaagt aagtatcgcc ccagtggata aacgcggatt tgtacgtgtc gacgaattga
    11581 aagaattaat aagaaaagag acagtattag tctctgttat ggctgtgaat aatgaagtag
    11641 gatcgattca gcccatccag gaaatcagtg atcttttgga tgattttcct aaaattcatt
    11701 tccatgtaga tgctgttcag gcgattggaa aagtaccatt ctcgcaatgg ttgacagaaa
    11761 gagttgattt tgcaacattt tcagctcata aattccatgg cccacgggga actggtttca
    11821 tttattggaa aaagggtcgt cgtttagcac cattactgac aggtggaggg caagaaagaa
    11881 atcagcgaag tgggacagaa aatgttccag gtattgtggc tatggttaaa gctttacgtt
    11941 tatcattaga gataaaggaa caaaaacctg agcagacaca acgcttaaaa gtagctctaa
    12001 tcaatgcgtt gaagacgtat gagaaagtga cgattttttc agaaggaact gactatgcac
    12061 cgcatatttt atgttttgct ctaaaaggaa ttcgcggcga agttctcgtc catgccttag
    12121 aagaaaaaca aatatttgtt tctactacta gtgcctgctc ctcacgtaaa catatggcaa
    12181 gcagtacatt gcacgcaatg catgtaccaa atgatctggc tacatctgct gttcgaatca
    12241 gcttagatga aaacaattcg cttgcagaag tcgagcaatt tatgattatt ttcaagcagc
    12301 tttataagaa attttctgca atcaattaaa agaggagtgt tcttgtgaaa tacagtgaaa
    12361 ttatggtccg ttatggggaa ctttcgacaa aaggaaagaa tcgaaaaagc tttatcatgc
    12421 aactagcaca aaatgtcaga caagctttga aagactttcc agaaatcaaa atccatgctg
    12481 atcgggaccg gatgcatctt ttattgaatg gcgcagacgg gcagctagtt attccaaaac
    12541 tagcaaaaat atttgggatc caaaatttct ctccaagtat tcgtgtagaa aaagatgtcg
    12601 aagttttgaa acaagctgtt caagacatca tgaaagaaat ttatactggg aaagaaacat
    12661 ttaaaattat cgctaaaaga agcgatcacc aatttgaatt gacaagtaat gaattgaatc
    12721 aaacattagg taatgctgtt tttgatattt tcccgcatat ccaagttcaa atgcgtcaac
    12781 cagatattcc attacgtgta gagattcggc gtgatggcgc ttatctatcg tatgaaacga
    12841 tcaagggagc tggaggattg cccgtaggaa caagcggaaa aggaatgctt atgctttctg
    12901 gggggattga ttctcctgta gcagggtact ttgccatgaa gcggggagtg gaaattgaag
    12961 ctgttcattt tgctagtccg ccgtatacaa gtgaacaagc actgcaaaaa gcaaaagatc
    13021 taacagccaa actagcacct tatgtgggaa cgatccattt tatcgaagtg ccatttaccg
    13081 agattcaaga agaaatcaaa aagtcagtgc cacaaggata ttggatgaca attactcgtc
    13141 gaatgatgtt gcgtttgacc gatgaaattc gccgtattcg tcatggttta gtcattttga
    13201 atggtgaatc attaggtcaa gtggcttcac aaactttgca aagtatggtg gctatcaatg
    13261 aagtaacgaa tacgccaatc attcggcctg tagcgacaat ggataaactt gaaatcattg
    13321 aagtagcaga acagatcgat acatttaatc tttctatcca gccttttgaa gattgctgta
    13381 cgatttttgc tcctccacag ccaaaaacac gccctcaact ggaaaaggtc catcaatatg
    13441 aagagcgttt agcaatagat gaaatgatcc aacgagcact agctggcttg aagatggaag
    13501 agatacaagc agaatcgtct aatgaaaaaa ctgaagaatt ttcagaattg ctataagagg
    13561 ttatgaaaat agtgttttga ccagagtatt agagaaacaa aacgaaaaaa tagctccatg
    13621 tattttaccg tttttgaact aatgtcgaag attagctgat tgaataccat ttatcaagaa
    13681 gttatggaaa agccggttct tttttactaa ctgaaaaata aaattttatt tagagatcaa
    13741 gctacagttg ataaatgata taaaaaagag aatttcccat gaaatagcga ggttgtgaca
    13801 gaagtgggca gcttcaagaa ataagaagga atttacgaaa attgcttttc aaatttttgt
    13861 gaaatttcgg cttatttttc gaagaagtta cttctggaac accgtgtatc agaggttgcg
    13921 aaaaagctgc cctgcatcaa gtaataagaa cagccaaaca aaaatagttc ctcatatttt
    13981 acgtttggtt gagcttatta ccgcagatgc aagcttttga acaccgtttt atttgtctca
    14041 cacccttttc cttcctactt gtaaccttgc tcccgtgtta gaaacatgtt acactaaata
    14101 tgtgaaatta ttaacaagga gcgtcgttat gcgagaaaaa acagatacac tgccaaaagc
    14161 aactgcgaaa agattacctt tatatttacg ctacttgaag atgctggatg actcaggtat
    14221 aagtagaatc aaatcaaatg agttcagcga aatcacccaa attccttctg caacgatccg
    14281 cagagacttc tcgcaattag gcgagctagg cagaagcgga tatggctatg atgtcccttt
    14341 tcttatcgat gtattcaata atatccttaa tactaaagaa gaaaaacgaa tcgcattagt
    14401 aggatatgga aatcttggca aagcattgaa acacaacaat tttagaagaa atgaaaatct
    14461 aaatatcgtg tgcgtctttg ataatgatcc agcactgatc aatcgagtaa ttgatggaga
    14521 aatgatctat ccgattgatc gtttcgcgga gatagccaaa gcaaaaaatg tgacagtagc
    14581 aatctctacg gtaccaagta aatattcaca atctgctatt gatgaaattg tcaaaggaaa
    14641 tgtaaccgct atacttaatt ttgcgcctga cagagtaact gtcccagctt atgtcaatgt
    14701 tcaatacatt gatttgacaa ccgagttgca gacgcttatt tactttgatg agaattactc
    14761 agaagttttt tcttaggaaa atttgagtag gcttattgat cttgcgagaa ctcgtcgtaa
    14821 ttctttcaaa aattttttag tactaaatga agtggttttt tcacgaccac ttgttgacta
    14881 aaaaaaaaaa ccattgtaga atgaagcata acgctgaaca agaggagtaa ctggcacatt
    14941 cattcttaga gagagaacta tctgctgaaa ggttctcaat gacaaccagt gaaggtagct
    15001 tgggagtttc tgtcttgaat ggagtagaga tagacgagtc gtgatcgtta actcacttga
    15061 gaggcaataa tgattgatta ttgcaattta ggtggtaccg cgtaaatcat acgtcctaga
    15121 atacgaaagt attttaggac gttttttagt ttaaaggagg aaaacagcat gacggaagaa
    15181 aataacctat caacaaaata taatccgcaa gaagttgaag ctggacgtta tcagcattgg
    15241 ttagaacaag atttgtttaa accgagcgga gataaaaaag caaaacctta ttcaatcgta
    15301 atcccgcccc caaatgttac tggaaaactt catttagggc atgcttggga tacgaccttg
    15361 caagatatgc tgattcgtca aaagagaatg caaggatatg atactttatg gctgcctggt
    15421 atggaccatg caggaatcgc gacacaagca aaagtagaag cgaagcttag agagcaaggg
    15481 atttctcgtt atgatctagg tcgtgaaaag ttcatcgatc aagtgtggga atggaaagaa
    15541 gagtatgcga gccacatccg cgaacagtgg gctaaaatgg gcttatcttt agattacagt
    15601 agggaacgtt ttacattaga tgatggatta tctgaagcag tacgtaaagt ttttgttacc
    15661 ttatacgaaa aaggtttgat ttatcgtggt gaatatatca tcaactggga tcctcaagca
    15721 cgaacagctc tatctgatat cgaagttatt cataaagata tcgaaggcgc cttttatcat
    15781 atgagctatg aactagcaga tggatcaggc gtagtagaaa ttgcgacaac ccgtccagaa
    15841 acgatgttgg gagatacggc gattgctgtt catccagaag acgagcgtta tcaagcgctc
    15901 atcggcaaaa aagtgattct acctttagtc aataaacaaa tcccaatcat tgcagatgaa
    15961 tatgtagata tggaattcgg gacaggtgta gtaaaaatca ctccagcaca tgatccaaac
    16021 gactttgagg taggtaatcg tcatgatctt ccacgcgtaa atgttatgga tgatgatggt
    16081 acgatgaatg aactagcagg aaaatatgct ggaatggaac gttttgctgc tcgtaaagca
    16141 atcgtgcaag atctgaaaga aatcggtcga ttgattaaaa tcgatacgat gatccacagt
    16201 gtgggtcatt ccgagcggac aggtgtcgtt gttgaacctc ggctgtctac tcaatggttt
    16261 gtaaaaatgg cgccgttagc gaaaaaagcc attgataacc aagaaacaga tcaagcagtg
    16321 gaattcttcc ctccaagatt caatcaaacg tttttacgtt ggatggaaaa tgtccatgat
    16381 tgggtaatct cacgacaatt atggtgggga catcaaattc ctgcatggta tcacaaagaa
    16441 acaggtgaaa tgtatgtagg gatggaagca ccagcggata gtgaaaactg ggtacaagat
    16501 cctgatgttt tagacacttg gtttagttca gctttgtggc ctttctcaac aatgggctgg
    16561 ccagatacgg aaagcgaaga ttataagcga tacttcccta ctagcacttt agtaaccggt
    16621 tatgacatca ttttcttctg ggtaagcaga atgattttcc aaagcttgga atttactggc
    16681 gaacgtccat ttgagaatgt cttgattcat ggattgattc gtgacgaaca agggcggaag
    16741 atgagtaaat cattaggtaa tggaatcgat ccgatggaag taatcgaaaa gtatggagca
    16801 gatgctctcc gctggttctt atcgaatggt tctgcaccag gacaagatgt ccgcttcagc
    16861 tatgaaaaaa tggatgcttc ttggaacttt atcaacaaaa tctggaatgc ttcacgtttc
    16921 gttatcatga atatcgaagg aatgaccgta gaagagatcg atttatctgg agaaaaatca
    16981 gtggctgacc ggtggatcct tactcgtttg aatgaaacga tcgaacgagt aactgagcta
    17041 tttgatcgtt ttgaatttgg tgaagcaggt cgacaactgt ataactttat ctgggatgat
    17101 ttttgtgact ggtacatcga aatgagtaaa gaagtacttt atggagatga tgctgtttca
    17161 aaacaaacca cccgtagcat cttagtccat acacttgatc agatcctacg tttattgcat
    17221 ccaatcatgc cattcgttac agaagaaata tgggaacata ttcctcatca gggaaattct
    17281 ctagtagtgg cagaatatcc tgttgtacgt ccagagtttg atgatgaaac agcttctaaa
    17341 gggatggaag tattgaaaga attgattcga gccgttcgaa atattcgttc agaagtgaat
    17401 acaccattgt ctaaaccaat tacgttgcta attaaaacaa acgatgctaa aatcgatcaa
    17461 tttttagttg aaaatacaag ctatatcgaa cgcttctgta atcccgaaga gttgacgata
    17521 tcaagtgaga tcactgcgcc agatctagcg atgtcagctg ttctgacagg tgcagaaatc
    17581 ttcttgccgt tagcaggatt gatcaatatt gaagaagaaa tcaaacgatt agaaaaagaa
    17641 ctggaaaagt ggacaagcga agtaaaacgt gtccaaggaa aactttctaa tgaacgtttt
    17701 gtttctaacg cgccggaaga agtagtagag gcagagcgtg caaaagaaaa agattattta
    17761 gagaagcaaa cggctgtcaa agaacgaatc gaaagtttgc gtactattca ataagaatag
    17821 aaaaagagag tgtgaaatca gctagctatt actaaaagct agctgattga acatcgttac
    17881 aggaaagagt ttgagcctca ctcttagctt cgattcataa ggagatgtga cataaatttt
    17941 gtcgcatctc ttttttagtc tactcttatt atgtaggaga aggagggagg tggatcatgt
    18001 atcaagagtc aataaagtag ttgataaaat cgttcctctc tctgtttctt ttctctttgt
    18061 catactttta tttttcttat gtgttctatt tgttataata aaagagaaat gggggaattg
    18121 ttgatgacga ttgaagaagc aatagaatgg atccatagtc gattaccatt tggttcacgt
    18181 cctggccttg accgagtcga agctttatta gaagtggtag ggcatccaga gagaaaagta
    18241 aaaacgatcc atatcgctgg aacaaacgga aaaggttcta ctgtagctta tttgagaagc
    18301 ctattagaag aggctgggct gacagtaggt acatttactt caccttatat cgaaacgttc
    18361 aatgaacgga tcgcaatcaa tggcaaaagc attccagaca atgatttgat ccagcttgta
    18421 aaaaaatatc agccactgat caaacaactt gatcaatttg aagcagtagc tggtattact
    18481 gaattcgaga cattaacagc aatggcattt gattattttt tgatgaagaa agtggacgta
    18541 gcgattatcg aagttggctt aggcggctta ttggattcta ccaatgtagc tgtaccaatg
    18601 ctgacgggaa taacaacgat tggacttgat cataccgaaa tacttggaga tacaattgaa
    18661 gaaatcgctg cacaaaaagc tggaatcatc aaacaaggcg ttccagtagt aacaggaaat
    18721 attgccccag aagcttttac tgtcatccaa caaacagcta aagcaaaaaa tgcaccgctt
    18781 tatgtatacg gggaaaatta taaaataaac tatctgcatc ctgatgagat gtggggagaa
    18841 gtatttgaat tttttaatga aataggaaag atccctcaat taaccactcc gcttttaggg
    18901 caacatcaag ctgaaaatgc aggagtagcc atcgaattgt attttgttta ctgtcaattg
    18961 gaaaagctgc ctttccgaga aaaagatgtt ttgaagggat tgaagaaatc tcgatggcca
    19021 ggaagaatgg agcgtttgag taacgagcca ttagttgttt tagatggtgc ccataatacg
    19081 catgcaatga accggcttgt tgagaatttg aaaaaagaat tcaaaggata tcaaatcaac
    19141 attttgtttt ccgccttacg aactaaaaat gttagagaaa tgctagaacg attgcagcaa
    19201 gtaccaaatg tccatattta tttgacgacc tttgaacatc caaaagccat cgaattaagt
    19261 gaagtatcag atttagcaag tgagagagta tcaatcgttt cattgtggca attcggatta
    19321 gcagatatat tggaaaagat gacaaatgaa gacgtattag ttgtgaccgg ttcactttat
    19381 ttcatttcag aagttcgcca tttattaata caattaggag gagatcatga agtataatgc
    19441 agtgattttt gacatggatg gtttgctgtt cgacacagag ttagtgtatt acgaagccac
    19501 acaagtagta gcagacaaga tgggttttcc ttatgataaa gacctgtatt taaaattctt
    19561 aggtgtttca gatgaagaag tatgggcgaa ttatcatatg attttctcgg aatttggcaa
    19621 aacaagtgta caaagattca tagatgattc ataccaggaa acgcttgaac gtttttcgca
    19681 aggagcggta caaatgaagc ccggtgtgtt ggaactcctc tcttttttag aagaacatca
    19741 gattcccaaa gttgtcgctt ccagtaacca acgagcagtc attgaacttt tattgaagaa
    19801 gaacaatctg tttgaacgat ttgagacgat tgtttctgca gaaaatgttc aacgagcaaa
    19861 accagaccca gaaattttct tgttagctaa tcagaagcta ggtacagcga agaaagaaac
    19921 attgatttta gaagattcac aaaatggtat tttagcagct tctgcggctg agatcccggt
    19981 agtcatggta ccagatctgc ttccaccatc ccaagaattg atcaaaaaaa cagctggggt
    20041 tgtttcttct ttacatgaaa tccctgcatt gttaaaataa aaatccatct cttttcgtat
    20101 cttattttag ataagataga aaggagatgt ttttttggga aaacgattga tcaaagaagt
    20161 acctactagc tctttaccaa gggaacgtat ggaaatttat ggcgcggaag ctttatcgga
    20221 tcaggagctt ttggcaatct tactgcgtac cggtcaacac ccttatagtg tgatgtcgat
    20281 tgctggaaat ctgttaaaaa cgtttggagg actggcctct ttacgacagg ctactttgca
    20341 tgagttagaa gagattcgag ggataggacg cgtgaaagca atcgaaatca aagccttgat
    20401 cgaattaggt cgacgaattc agacggatca tgaaagagcg gctccaccgg ttcgtaccag
    20461 ctacgaattg gcccagcaat tgattctgga aatgaaagat cacaaacaag aacatttggt
    20521 ttgtatttat ttggacacga agaatcaagt gatcttaaaa aaaacagtgt tcatcggttc
    20581 gctgaatcag tcagtcgctc atcctagaga aattttccat tatgctgtac gttattgtgc
    20641 agcaaggatc gttttagcgc ataatcatcc ttctggtaat gttattccat cgcagcagga
    20701 tatgaatttt accaaaagga tacaaaagtg tggagaaatg atggggatca ctgtactgga
    20761 ccacttgatc atcggacgca aacgatattt tagtttgaga gaagaaggaa tgatggaaga
    20821 gaagtaagtt gctttcttgc aaaaaaaatg aagcaagtgt acaattatat tgtaattttg
    20881 tttgggaata gaagttgaaa catctgttgc acctctatcg tacacgagca atgttacaat
    20941 ttaaattagt gcttttggca cgaggaggat attattatgg aaaacggaac agtaaaatgg
    21001 ttcaacgctg aaaaaggatt tggatttatc tcacgtgaag atggaagcga cgtattcgtt
    21061 cacttctcag ctatccaagg tgacggattc aaaacattag aagaaggtca agcagtgact
    21121 ttcgacgttg aagaatcaga ccgcggccca caagctgcaa acgttgtaaa agcttaattt
    21181 tatctgtaaa tcaaattgat ggtagacatc aatttttacg agagaacaaa gcgagtaaca
    21241 aaaatacctg ccacaagaga caatttctct tgtggcaggt atttttttgt atgaaaaagt
    21301 aaataaattt aagaggctat gaaagagcca ccttgtatca aggaataaga acaaacaaaa
    21361 atggcttctc atgtttttca tttgttttct cttatattca ggacaaggtg ctgatttcat
    21421 aacctcttat ttattcttca tctggtgtca ttaccattgg caaaatcatt ggatgtcttt
    21481 ctgtacgttc gaataagaaa ggctgaagcg cgccagtcat cgcttctttc aatttatatt
    21541 ctgaacagtc aggtccattc aaacattctc ttaaagcgtg gaataagatt cgctgagctt
    21601 cattgatcat ttctcctgat tctcgcatgt agacaaatcc acgagagaga atatctggac
    21661 cagccaagat ttcttttttc ttgatatcca ctgtcgcgac agctaataca agaccttctt
    21721 ctgaaagcag gtgacggtca cgtaaaacga cattaccaat atcaccgatc ccgctaccat
    21781 cgatatacac atctccagcc acaaaatgcc cagcaggacg cgcagaatcg ctagttaacg
    21841 ctaaaacatc gccattttcc atgatgaagc agttttctgc aggaacacct acatcttgtg
    21901 ctagagaagc atgtactttc aacatgcgga attctccgtg gacaggaata aaatattttg
    21961 gcttcatcaa acgaagcatt aatttttgtt cttcttgtcc accgtgaccg gaagtatgga
    22021 tgttattgat ttttccgtga atcacttctg caccagcttc agacagcaaa ttgatcaaat
    22081 gattgacact tgttgtatta ccaggaatag gtgaacttga aaagatcact gtatcgtctg
    22141 gctggatttg gatttgacgg tgagtaccat tcgcgatgcg gctcaacgcg gccatcgctt
    22201 ctccttgaga acctgtacat aggatcatcg tttcattggc aggcaagcga ttgatttcgt
    22261 gtgcatctac aaatgtgccg tctggaactt tgatatatcc taaacgttga ccgttgacga
    22321 tggcattttc catgcttcgt ccgaaaacag cgattttacg accagttgcc acagcggcat
    22381 ctgctgcttg ctgcaaacgg aagatgttag aagcaaagct ggcaaaaatg atacgtcctt
    22441 cgatttttga aaagatcttc aaaatagaat gcccaatcgt tttttctgat ttagtaaatg
    22501 ttggaatctc agcatttgta ctatcagata aaaggcacaa gactccttct tccccgatac
    22561 gagccatttt atgcaagttt gctggttcgc caacaggagt gaaatcgaat ttgaagtctc
    22621 cagtcgctac gatatttcca gaaggtgttt tcaccacgat ccctaatgca tctgggatac
    22681 tatgggtcgt tctgaaaaag ctgacagaag tctttctaaa acggatgatc gtatcttcat
    22741 tgatctcatg gagctctgca tctcgaagca agccatgctc atctaatttg tttgtgatca
    22801 acgctaatgc gagaggacca gcatagatag gaatatttgc ttgtttcagc aagtagggta
    22861 ttccgccgat gtggtcttcg tgcccgtgag taatcaccaa ggcttttact ttgtgtaagt
    22921 tttgtatgat gtagctgtag tcgggaatga catagtcaat tccaagtaaa tcgtcttccg
    22981 ggaatttgat cccggcatca atcaaaatga tttcatcttg gaattgtacc ccatacgtat
    23041 ttttcccgat ttcacctaat ccaccaatag caaagacgcc tgtctcgtta tttttgatgg
    23101 aaagtttcat attaaaactc cactaatgag aaatcagcat tttctttttc gtactctaga
    23161 tgacttcctt ctagaagttg aacgaattca atattgtatg gggtattttc ttccacacgt
    23221 tggcgagcgt ctacatcgct ttttgcctca atgtaaagag attttgtttc ttcccgttta
    23281 gggttgcgta cttttgtttc ttgataataa actttataga tcattgtttt gtctccttta
    23341 tctgcgtaaa gcagtgattt agctagttga tttttttaga caacacaaaa cgaggggaca
    23401 agccacctgg tttttcatat gctttgacta gaatactgga ttcgagtcaa agagacaagc
    23461 ctcgtttttg cttatctgtt cggatatttt ttcaaccgta ccttctgtat aaaaaatata
    23521 caacaattaa ttgttattct agcataaaac agcaaataag tatagaaatc aactagattg
    23581 aaagaaaaaa tcaatgttta tcatcccgct ataatcataa tgactttttt atgagagaag
    23641 tgttctatta ataggctcgt tgtgctatca tttttagtaa tgaaaatgta acaaaagatt
    23701 aaaaggagat gagaaagtga aactaatgtg gcattatacc atgcgttata agaaattctt
    23761 gtttttcaat ttcatatgcg tatttggttt tattttgatt gaattaggac ttcctacgat
    23821 tttagcacgt atgatcgatg taggaatccg caatgatgat tttgattatg tgaagcaaca
    23881 agggatattt atgatcgtta ttactgtaat cggtattatt ttgaatatct tgttaggtta
    23941 ttttggttcg aggattacga ctaatatcgt agcagatatt cgagatgatt tgttcgaaaa
    24001 gatccaaagt tattcgcatc aggaatacga aaatctaggc gtatcttcat tgatcactcg
    24061 tacaacaaac gatgcttatc agatcatgtt gttcctgcaa aatattttac gtatcggttt
    24121 tatggcacca atgatgttca ttgtcagttt gtacatggtc atgcgtacaa gtgtgacact
    24181 cagtttgtat gtagtaggtg cattaccttt actattattg gcagtcgtag cgattgctaa
    24241 ggtgtctgaa ccgttatcta aaaagcaaca aaaaaactta gataaaatca acagtatctt
    24301 gcgggaaaat ctttcaggat tgcgtgtgat tcgtgcattc gtcaatgaaa agtttgaaga
    24361 aaaacgtttt gctgtagtca atgagaatta tgcttctagt tcaaaaagct tattccgttt
    24421 gatggctgtt gcacaaccgg gtttttattt cttatttaat atcgtaatgg tattgatcat
    24481 ctggagcggg gcagtgcaaa tcgatgcagg cgagcttcgt gtaggagatt tgattgcgtt
    24541 tatcgagtat atattccatg ccttgttctc attcatgtta tttgctagtg tgttcatgat
    24601 gtatccaaga gcagctgttt cagctggacg tatccaagaa gccctagatg ccaaaccttc
    24661 gattgtagaa gatccaaatg gtatatctga tacaaaaact aaagggtata tcgaatttca
    24721 aaatgtaaca tttgcttatc caggccattc gcaagagcca gtgatacgaa atgtcagttt
    24781 tacagcctct ccaggagaga ccgttgcttt tattggaagt accggtagcg gaaaatctac
    24841 gttgatccaa ttgatccctc gcttttatga tgtgagtgaa ggaaagatct tgatcgatgg
    24901 agtagacgtg agagattatc ggctaagcaa gttgcgagat aagattgggt ttattccgca
    24961 aaaagcgctg ctatttactg gaacgattgc agataatttg cgatacggga aagaagatgc
    25021 tacgcaagaa gaaatggaac gtgcagctga gattgctcaa gcttcagaat tcatttctcg
    25081 aaaaccagat ggatttaatg aacatttatc agaaggtggt tccaattttt caggtggaca
    25141 aaaacaacga ttggcaatag ccagagccat catacgccgt ccggaaatct atatttttga
    25201 tgacagcttt tctgcattag attatcaaac ggatgcgaag ttacgtgctc gtctgaaaaa
    25261 agaaacgaca gaatctactg tattgatcgt agcacaacgt gtgggaacga tcatgcatgc
    25321 agataagatc atcgtattaa atgaaggaga agtcgtcggt atggggacgc atcgggagtt
    25381 gttggaaaaa tgcccgattt attatgatat tgccgcttct caattatcaa aggaggaatt
    25441 agcatgaaaa aaaccttttc ttccttaaaa cgtttagctc gatatatcag accgtatcgt
    25501 gagacttttc ttttagtgat cctatttaca gttctgacag tggctttcaa cgtggctttg
    25561 ccatatgtta caggacttcc tactacagaa atcagccgta atattgccaa tggcgaatca
    25621 atcaattttt cttatatatt caaatgtctc atttggatca cagttgttgg aatagggtat
    25681 tgtatttcgc aattactttc tggtgttttg atgacaaatg tcgttcaaag tgccatgcat
    25741 gatttgagaa gagacataga agaaaaaatc aatcgtcttc cggtttcata tttcgataaa
    25801 aaccagcaag gaaatatttt gtctcgtgtg acgaatgatg tagatgcagt cagcggtgct
    25861 ttacaacaag cttttattgg tatcgtaaat gcgatattgg gaattacgtt ggctgcagca
    25921 atgatgtttt atatccagcc gatgatggcg ctgatctcta tgatcatgat tccaacatcg
    25981 atctggatct caaaacgagt gatcaatgct tcgcagaaat attttcaaag catgcagaat
    26041 tctcttggtg agctaaacgg ctacgtccaa gaaaatatga caggttttag tgtattgaaa
    26101 gtatatggac gcgaaaaaga aacattggaa ggattcaaaa aagttaatca cagcttgaaa
    26161 tactttgggt ttcgtgcagc attcatttct ggcttgatga tgcctctagt tcaattaact
    26221 gcctatgcta cttatattgg tatggctgtt ctaggaagct tttatgttat tactggggcg
    26281 atcgttgtcg gtcaactaca agcattcatc caatatattt ggcaaatcag tcagccaatg
    26341 gggaacgtga cacaattgtc ttcagttttg caaagtgcat cagcggcaac gaaacgtgta
    26401 ttcgagattt tagatgagcc agaagaaaaa gaaaacaaag tagatgcttc actgccagaa
    26461 acgattttag gagatgtgac attcgatcat gtcgattttg catatgatcc gaagaaacca
    26521 ttaatccaag atttgaattt tgaagtgaaa gctggtcaaa ccgtagctgt ggtcggtccg
    26581 accggtgccg gcaagacgac attgatcaat ctattgatgc gtttttatga cgtagacaaa
    26641 ggagcaataa ggattgatgg aatcgacacc aaatcaatga gtcgcagtga tgtgcgttcg
    26701 ctatttggta tggtcttgca agatgcatgg ctttatcaag gaacgattgc agataatatc
    26761 cgcttcggaa agcttgatgc gacagattat gaagtagttg atgctgcgaa aacagcaaac
    26821 gtagatcatt ttatccgaac gatgccagat ggatatgata tggccatcaa ttctgaggga
    26881 gacaatgtgt ctttaggaca aaaacagttg ctgacgattg cccgagcagt ggtctccgat
    26941 cctaaaatct tgattttaga tgaagcaaca agttcagtag acacccgttt agaagcgttg
    27001 attcaaaaag caatggatcg cgtgatggag ggacggacaa gtttcgtcat cgctcaccgt
    27061 ttatcgacaa tccgtgatgc agatctgatt ctagtgatgg atcaaggtca gatcattgaa
    27121 aaaggaacgc atgagagttt attggcacaa ggtggatttt atgaaaaact gtataacagc
    27181 caatttgctg aggaagcaga ataagtcata taagaataaa acagtttaaa acttattttt
    27241 tgttctctat tcttgataat ggtaaagtaa agttatcaag aaaagtgagg acacggagat
    27301 ggaacagttt ttaaatgaaa aaattactga agccaaaaga gaagttgatc gtttaacgca
    27361 cgtctgtcag acgaagcctt ttgattcagc tgattttttt gaaaatgagt ttcaaatcga
    27421 acgcttggca gcacaaatag aagtgtacga attaatttta aaaaaagtaa tagaagaaaa
    27481 tatagatgta caataaaaac aggtaaaacg tcagttacca gatactgtaa atagacatct
    27541 ggcctgagca ggttttacct gttttttttc ttatgaaata aatatatgct atgatacctt
    27601 tattcaatag gattagtttc tacaaaaaat gaaaggagaa aaataaatat ggaacggttt
    27661 atagcatcaa atgccacagt gattggtgat gtgacattgt cagaagatgt gacgatctgg
    27721 tatcaagctg ttttacgcgg ggacagtaat tggataaaaa taggacaaag aacgaatatc
    27781 caagatggta caatcatcca tgtcgatcat gatgcacctg tagatattgc ggagaatgtg
    27841 acggtaggac atcagtgcat gctacatggc tgtacaatcg aaaaaggggc gctgatcggg
    27901 atggggacca cgatattgaa tcatgcggtt attggtgaga atagtttgat tggtgctgga
    27961 tcattagtaa cagaaggaaa agttattcct cctaatgtct tggcttttgg tcgcccagct
    28021 aaagtgatcc gtcctttgac aaaagaagaa atacaaaaaa acaaagaaaa catccagcat
    28081 tatgtcgaga taggtcggat gcatgcgcaa ggaaaattca aggagcaaag ataggcagta
    28141 gcatccataa aataaaaaag gatggtcagt ttgagttgac catccttttt tatttggttt
    28201 agataagaga gcttaaaaaa gcttcctttg aaacagatta atttaatgaa gaactgtttt
    28261 ccatgacttc atcgatcaat ccatatgctt ttgcttgttc agctgtcata tagttgtcac
    28321 gatctgtatc tttttcaatc acttcaagcg gttgtccagt gcgttcagct aaaattttgt
    28381 ttaagcgttc gcgtgtttgc aaaatatggc gtgccgcaat ttcgatttca gttgcttgcc
    28441 cttgagcgcc gccaagaggt tgatggatca tgatctcagc atttggtaaa gcaaatcgtt
    28501 taccttttgt accagctgtc agcaagaagc ttcccattga agcagccata cccataacaa
    28561 ttgtttggac atctgctttg acaaagttca ttgtgtcgta aatagccata cctgctgtaa
    28621 ctgaaccacc aggagaattg atataaagat agatatcttt ttcagaatct tgagcgtcta
    28681 agaaaagcaa ttgggcgatg atcgaattag caagatcatc tgttacttgg ccgcttaaca
    28741 tgatgatacg gtctttcaat aaacgtgagt agatatcgta agctctttca cctcgtgaag
    28801 attgttcaat gactgtagga attaaattca taatagagtt cctccttgat ttcgtttaga
    28861 aatagtgtac cataatttag tttctaatac ctaaaatgta gtatacattt ttggtcaaaa
    28921 aaggtcaaat aaaaaactta ggcaaattag tcgcataaac ccgctttatg gtatgataag
    28981 cagagaaaca aaacaaggag gaacaacaga ttgatagttg gtattactgg ccttatcgga
    29041 gtgctgacag gtgctgtagt tgtctatatc ggcatgatac tgcaaatgcg tcacttggaa
    29101 aataaagaac agcgtagacg tgaattggaa ttgaaagtca aagaaatcga gacgctgaat
    29161 caattaaata aaaagatcaa cgagatcttg caaaaacgga caacgctgat ggaagaatat
    29221 gtcagctttg atgcatttga tgattgttat atcacgattg acgattttgc gtatctccaa
    29281 tcattttcag cgcaaaatag tttttatctg ccaaattata ttttagacga gctatttaag
    29341 aatatctccc atcgaaaagt gattttatct ccagatgaaa caatgaagat tggtggatat
    29401 gcttataaag gcggacgcgt gattttagag aattttacgg atagtctgac tgaaatgatc
    29461 aatgaaaaaa aagctcagtt gaagactatg acgcgccagc cgattggttt cttctcgaaa
    29521 gatgatgttt ggagctgata ttttgaagca ttgccgttgc acatgagagc gtggtaatgc
    29581 tttctttttt tcttaatgat acaatagaac tgaacggagt gaagaaagat gttacaaatc
    29641 tatgcccatc gcggaagcag cggcacccac ccagaaaata cgcttcctgc atttgcagaa
    29701 gctgtacgag taggtgcaga tggtatcgaa ctagatgtcc atctaagcaa agatggttat
    29761 ttgatcgtta tgcacgacga agaagtggac cggacgacta acggtaaagg gctgattcga
    29821 gaaaaaacat tggaagaact caaaaaattg aatgcagggg gcaaattcag caaagaattt
    29881 ccagcagcta aagttcctga attgagagaa gtgttaggac tgctcctcca aaaaaattac
    29941 cgagggatgc taatgattga aattaaaact gatcagtatg aatatcccgg tatcgaagaa
    30001 aaattagccg aaacattaaa aagtagagat tggccttttc aacatgcata ttgcagcttt
    30061 catttggatt ctttggaaaa aatcgcatta ctggaaccgg agatacagct ggacttattg
    30121 atgagtactt ctgataaaaa gatccaacta gcagcagaaa ccccttatat agaaggagta
    30181 catccaaaaa atacttggtt gttcgaacat ccagtccagg cagctgattt tccaaaagca
    30241 attcgtgcat ggacgattaa cgatgaagaa gaaatggcca aatgtcaaga actcaaaata
    30301 gatggaataa taactgattt tccggagaaa gctcttcggt ggaaacaatc aacgaaaagt
    30361 aggtaaaata tggaaaaagt attagtgatc gtcggtccga cagcagtcgg taaaacagcg
    30421 ctaagtgtgg aactcgcaca actatttgga ggagagatca tcagtggtga ttcattgcaa
    30481 atctataaaa atctggatat cggtacagca aaaatcaaag aagaagagat gaataatgtt
    30541 ccgcatcatt tgattgatgt gatcgaacct actcaacgtt actcagccgc tgattttcag
    30601 cattcaggtc gacaattgat taccgagatt gcgaaccgag ggcacctacc tatcatagct
    30661 ggtggtacgg gtctctatat ccaatccctt ctatatgatt atcagttagg agcgacagaa
    30721 gaagcgaatc ctgagattag aaaaaagtat gaaacgttag ctgaaacaat tggttcccaa
    30781 gcattatgga atcagttgaa agaaaaagac ccggcagctg ctgagaaaat ccactggaac
    30841 aatcaacgca aagtgataag agctctggaa gttttagaga cgacaggaca tagtatcacg
    30901 gcacctaaag aagagccaaa gcaattgtat gattacctca tgattggatt agatacgaag
    30961 cgtagtattc tttatgaacg aatcaatcaa agagtcgatt tgatgctagc agaaggttta
    31021 gtagcagaag cgcgtaaggt gtatgagctt ggagaagtcc aggccagtca aggtattgga
    31081 tataaagaat ttttccctta ttttgaaggg aaagaaacat tggaagaagc aacagaacaa
    31141 gtcaaactac attcgagaag atacgcgaaa cgtcagttga cgtggtttcg taaccgtttg
    31201 gatgcacagt ggtttgatct tataagtgag ccaaatcaaa aaagtcagat tgagcaaaca
    31261 atcaaaaaat ggctggaggc ggaataaaat ggaagaaaaa gtgatcatcg taggggtaga
    31321 aaccgaagca aaccagcgtt acttttcaga gtcaatggaa gagctagttc agctgacgaa
    31381 taccgcatca ggagaagtcg tattcacaat tacacaaaag agaccacaag tggatcggca
    31441 aacgattatc ggtaaaggga aattacaaga attagttcaa caagcggatg cgcatgaagc
    31501 ggatttgatc atctttaatc atgagctaac tccgagacag agccaactga ttaccgatgc
    31561 tgttggtctt ccggtaattg atcgcgtgca gcttatctta gatatttttg cgatgcgtgc
    31621 tcgttcgaaa gaagggaagc tgcaggttga acttgctcag ttagaatacc tgctgcctcg
    31681 tttagtaggg caagggaaaa cattatctcg tcttggcggt gggatcggaa caagagggcc
    31741 aggtgaaaca aagttagaaa cagaccgccg acatatacgg aataaaattt ttgctgttaa
    31801 gaaagaattg aaagaagtag aagctcatcg agagcgcaat cgccaaaaaa gaaaaaatag
    31861 cgagattttt cagattggac ttattggcta cacgaatgcc gggaagtcaa ctatcttgaa
    31921 tctattgaca caagcggata cttattcgaa agatcaattg tttgcaacgt tagatccatt
    31981 gactaagaga tggcgttttg ctgaaggatt tgagattact gtaacggata ccgtcgggtt
    32041 catccaagac ctgcctacgc aactgatcga tgctttccat tctacattag aagaaagtca
    32101 aaatatggat cttttgctac atgtagtcga tgctagttct ccagatcgta ttttacagga
    32161 gcagactgtc ttaaaattga tggatgaact gaatatgaaa gaaatgccga tactgactgt
    32221 ttacaataag gcagaccaga tcgacccagc gatgttcacg cctacgctat tcccaaatgt
    32281 attgatttct actcagacga aagaaggtaa gatggcgttg atcgaagcaa tcaaacgtca
    32341 gctgatggaa ctaatgaccc cttatacact ttctgtgcca agcaacgaag gacagaaatt
    32401 aagcgagttg agaagacaaa caatggtttt ggacgaagcg tacatggaag aaacaaacga
    32461 atatgaagtt aaagggtttg caaaaaccaa ttcaaaatgg ttaagaaaaa accaataaaa
    32521 ttttattttt ttaa
//
LOCUS       DBBGSZ010000030        30130 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.030, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000030 DBBGSZ010000000
VERSION     DBBGSZ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 30130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30130
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.030"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(26..328)
                     /locus_tag="ACIZE5_001891"
     CDS             complement(26..328)
                     /locus_tag="ACIZE5_001891"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC6109014.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(353..2446)
                     /locus_tag="ACIZE5_001892"
     CDS             complement(353..2446)
                     /locus_tag="ACIZE5_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGC6109015.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(2935..3699)
                     /locus_tag="ACIZE5_001893"
     CDS             complement(2935..3699)
                     /locus_tag="ACIZE5_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HGC6109016.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(3810..4679)
                     /gene="mdcB"
                     /locus_tag="ACIZE5_001894"
     CDS             complement(3810..4679)
                     /gene="mdcB"
                     /locus_tag="ACIZE5_001894"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046917 - triphosphoribosyl-dephospho-CoA
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0019361 -
                     2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HGC6109017.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(4704..5780)
                     /locus_tag="ACIZE5_001895"
     CDS             complement(4704..5780)
                     /locus_tag="ACIZE5_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGC6109018.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(5804..6397)
                     /locus_tag="ACIZE5_001896"
     CDS             complement(5804..6397)
                     /locus_tag="ACIZE5_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HGC6109019.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(6401..8077)
                     /gene="mdcD"
                     /locus_tag="ACIZE5_001897"
     CDS             complement(6401..8077)
                     /gene="mdcD"
                     /locus_tag="ACIZE5_001897"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HGC6109020.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNEIAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(8067..8366)
                     /locus_tag="ACIZE5_001898"
     CDS             complement(8067..8366)
                     /locus_tag="ACIZE5_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HGC6109021.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(8468..10114)
                     /gene="mdcA"
                     /locus_tag="ACIZE5_001899"
     CDS             complement(8468..10114)
                     /gene="mdcA"
                     /locus_tag="ACIZE5_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015451 - decarboxylation-driven active
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HGC6109022.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(10121..11032)
                     /locus_tag="ACIZE5_001900"
     CDS             complement(10121..11032)
                     /locus_tag="ACIZE5_001900"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HGC6109023.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            11152..12009
                     /locus_tag="ACIZE5_001901"
     CDS             11152..12009
                     /locus_tag="ACIZE5_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGC6109024.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(12196..12558)
                     /locus_tag="ACIZE5_001902"
     CDS             complement(12196..12558)
                     /locus_tag="ACIZE5_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HGC6109025.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(12747..12929)
                     /locus_tag="ACIZE5_001903"
     CDS             complement(12747..12929)
                     /locus_tag="ACIZE5_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109026.1"
                     /translation="MIFFISEYINQTPFYSKNTEKINGGQVSTDFSIIVYFSGAFTDD
                     KNFIMNLKNDTTKIKK"
     gene            12904..14343
                     /locus_tag="ACIZE5_001904"
     CDS             12904..14343
                     /locus_tag="ACIZE5_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6109027.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(14350..16902)
                     /locus_tag="ACIZE5_001905"
     CDS             complement(14350..16902)
                     /locus_tag="ACIZE5_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HGC6109028.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(17016..18347)
                     /locus_tag="ACIZE5_001906"
     CDS             complement(17016..18347)
                     /locus_tag="ACIZE5_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HGC6109029.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(18313..19791)
                     /locus_tag="ACIZE5_001907"
     CDS             complement(18313..19791)
                     /locus_tag="ACIZE5_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HGC6109030.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(20096..21931)
                     /gene="tdc"
                     /locus_tag="ACIZE5_001908"
     CDS             complement(20096..21931)
                     /gene="tdc"
                     /locus_tag="ACIZE5_001908"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HGC6109031.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            22401..23828
                     /locus_tag="ACIZE5_001909"
     CDS             22401..23828
                     /locus_tag="ACIZE5_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6109032.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(23920..24285)
                     /locus_tag="ACIZE5_001910"
     CDS             complement(23920..24285)
                     /locus_tag="ACIZE5_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HGC6109033.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(24282..24647)
                     /locus_tag="ACIZE5_001911"
     CDS             complement(24282..24647)
                     /locus_tag="ACIZE5_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HGC6109034.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(24839..25087)
                     /locus_tag="ACIZE5_001912"
     CDS             complement(24839..25087)
                     /locus_tag="ACIZE5_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109035.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            25086..25214
                     /locus_tag="ACIZE5_001913"
     CDS             25086..25214
                     /locus_tag="ACIZE5_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HGC6109036.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            25271..26965
                     /locus_tag="ACIZE5_001914"
     CDS             25271..26965
                     /locus_tag="ACIZE5_001914"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050151 - oleate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HGC6109037.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            27065..27238
                     /locus_tag="ACIZE5_001915"
     CDS             27065..27238
                     /locus_tag="ACIZE5_001915"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109038.1"
                     /translation="MQAFEHRLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKGV"
     gene            27616..28749
                     /locus_tag="ACIZE5_001916"
     CDS             27616..28749
                     /locus_tag="ACIZE5_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HGC6109039.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            28780..29100
                     /locus_tag="ACIZE5_001917"
     CDS             28780..29100
                     /locus_tag="ACIZE5_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HGC6109040.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(29129..29593)
                     /locus_tag="ACIZE5_001918"
     CDS             complement(29129..29593)
                     /locus_tag="ACIZE5_001918"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6109041.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(29725..>30130)
                     /locus_tag="ACIZE5_001919"
     CDS             complement(29725..>30130)
                     /locus_tag="ACIZE5_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC6109042.1"
                     /translation="ATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPI
                     VLNPIMFIPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGV
                     LAAVNLVLSILIYLPFVKVATIQERRKEALDA"
BASE COUNT         9098 a         6245 c         5202 g         9585 t
ORIGIN      
        1 tttttaccct cttttctttt tgtatttaga taactccctt atcttgcaga actggggtga
       61 ttttttcttc aatttcattt tttgaaacaa tatttttcaa atagatcatc gccgttttag
      121 gatcaactgc gaacttttcg aactgcgaac gaaaattttc tgctgtgatg atcacatctg
      181 gtttcatgga aactgcggaa gaaatatcac aatggtccag tttggcttct actcctaatt
      241 tgttcaaaac atcctcagca gacatctgtg ctgcaaaact acttcctaaa cctgcaccgc
      301 atacgaataa aatgttcaat ttgttcatct ttgttctccc ccgtatcatt tattatttct
      361 caactactga aaaaagcagt tgtttgaaat cttcgatatt tgtgcattca atcaatcgat
      421 ccaacttctc ttcgttgttg atcaattcaa ttagttcttt catgatgttc agatgcgagt
      481 aggagtctac tgctgccaaa caaaaaataa tctttactgg atccatttca ggattaccga
      541 aatcgattgg ttgctcaatc gtagctacgc tgactcctaa tttattgacc ccatcttctg
      601 gtcgggcatg ggctagtgcc atgtgtttgc caatcacgat atacggtccg taatcattca
      661 ctgcacgaat catcgcttcg acatagcgct cttcgacaat gttttcttta accaatggtc
      721 tagcagctag ttcaatcgat tcctcccaag tagtggcttt ttctttgatc atgatattgc
      781 tgtccgtcaa aatatctttt aacataggct ggatctccct tttgttgatt tctaaattgt
      841 ttgtttcgaa taatttttct aacttgccat agatgattcg atctactcgg ccaccacttt
      901 ctttcatgac atctattatt tgagtgaata actccgtcga ttcatgactg ttaggctcta
      961 accgctgtag ttcttcattt cttttcaaaa agtcttctat aaccaagata ttcgtctcag
     1021 ttaaaatcgg atcgacaact aaaagcggct tatttcgata attcaattga aaggtgctga
     1081 aaaccagatt gacatccaat ttatctacta attcgatttc ttttgaactt aaaactgcag
     1141 taatctcgat ctgaggaaac ttttctttca gattctctgc taacagattt ccagtagcca
     1201 tcccatggtt acagacaacg actgatttat aaacataatt caagtctcgc ttgattacac
     1261 tggcgatcgt cgaaaagtgg atgacaagaa aagctatctc gtcctccagt atcttgccac
     1321 caattacttc ttcgatcgta ggaacaaaat gagtgactgc gcggtagatt gggaaataat
     1381 ttgttcggat gttttctttc aatggattca tgacttggat atgattcttg attcttacaa
     1441 tcagtgcagc catgtgctta tagagatttt cgaataaagc ttcttccttt agatggaaag
     1501 gtacgtgtgt ctcgttctct acaaattgga tcaattggat cgttagtaat tgagcttgta
     1561 cccactcgat tgaattggag atatctctag cattgaacgt ctcaatagtg aaacgaagat
     1621 aatttctttc tacttgcggg acattgtcca attgaaattc ctcgatcatg tggtcaataa
     1681 atgcagaaaa gctactgtct tttatttctg tatttttcca attaatggca gagataaatt
     1741 catgtttcct gattcgctgg atccagatca atgtaaaaag caggatttgt tttttataaa
     1801 tatcatcttc ttgtttcaac aacttattgg aatagatctc ctgtattttt ttgatttcca
     1861 ccaaaggaaa ataatggaga aagatttttt gagccggtgt taattgtgca tcttgattca
     1921 taaagaagtc ggtcattccc agattctgat tgataaaatc atagatcatc gtacggatag
     1981 atcgttctga acctttataa accagtcctt gctttccata actgacgatc tctatcccat
     2041 aactgaccag tgttgctcgt aaccgtctca tatcttcatc taatgtactt ttagagattt
     2101 gaaattcttc ttcttttttg tttagatgga tcgggattcg gctgtaagca acggctaaaa
     2161 ctagatcaaa aatacgttcg cgccgattca aaaagccgtc tttcacatct tttatttcag
     2221 tttctaatcg agcttgcttt tccttttcca gcttcaacaa aaaacctttg ttgcgaattg
     2281 tacggatctc cggaagcttt ttactgctca accagatatt cgcttcaaga acttcctgac
     2341 ggatcgtccg ctgactgaca ttgaactcac ttgctagatg ttttgctttt actggatatt
     2401 gggctgtcat gattctgtga agtatttcaa ttgttcttgt tttcatagaa atgatctcct
     2461 tctgatttca agtatatggt tccgcttaca taataaaaag tagatatttc tgccacttga
     2521 agtggaaaga aagtaagcaa agcaaacaaa aaataagcca tatgcttttt catctcctca
     2581 acgaaaaaga catacgccta ttattacaaa aattttgccc atctatacaa aaaagaggtt
     2641 gtgaaaaagc tgtcctgcat caagtaataa gaacaactaa actaaaatag tgcttcctat
     2701 ttttcgtttg gttgttctta ttatcgcaga tgcaagcttt taaacaccat ttagtggaga
     2761 ggttgtgaca gagatgttca gccttgagcg ataagaagcg attttgaaaa atcgcttccc
     2821 atattttaca aaatcgtgcc ttattgccga taggctatct ctggcacacc gtttattcag
     2881 aaaaaggagc tgcgacaagg cttttgtcac aactccgttc ataaatattt cctgtcaatc
     2941 cagcataatc ggctgaataa aatcggcttg ccatcttttt tctttctcag aaaaatcaaa
     3001 ataccatatc tgagaaaaat actgtcgttg tgtcttactt cctgagatca atcgcccatc
     3061 ttttcgatcg actgaataat cacagcatct gaaatcaatt cggatggcaa aactattttc
     3121 gtggatctgt cgataatttc ctacttcctg aatagttatt tttttagtat gatttcttac
     3181 accgtctgct ttgttttttt gcagaacttt ctgatgttcg gcaaacagct tgtctgtata
     3241 acagcttctg gctttttcag gagtttcttc ttcccaagcg gattggatct tcatgaatat
     3301 cttttggatt tccagaaact gtgctttctt ttctttagcc gttcctgaca tgcgggacaa
     3361 tatctccgct ttcagccttt tcttttgtct tttattcttg acgatagaaa aagcagaaac
     3421 ccctcctact gacaaaacag ctaatgcaag aaatcccgtt tgctcataac tagaaggacc
     3481 tgtacctgga ccataatacc cataagaatc tctgccgtaa gaacgactgc caaaataact
     3541 gcccccatat gaacgaccac caaatgaacc tctgcccgaa cttcgaccgc tagatgtacc
     3601 tccaccatga ccacccgcga cagcgaatcc ttgggtcggc agagcaaaca aacataggcc
     3661 cactaacaaa atgattgcta aataattgat ttttttcatt gtcttcctcg ttatctttta
     3721 ttacaaaaaa ctatttttat gatagccttg ctaaaaggaa gagtcaataa ccagatgcat
     3781 aaactgtttt tttagcaatt ttgtcttatt tagtcattga gtaacatcgg acaaatgtat
     3841 gtgtcggcag tccataattc ctctatcttc agcatgaaca agcttgcaga caagagatct
     3901 gcgcttcctc caggagagat ttggttttcc tgacaaaagt gcaacagtgc tgtaaatgga
     3961 cgatttggta aagcactttg actagcagca tgagcaagtt tttgcatttc cactaacgtt
     4021 ttctgatcac tgcgatgcaa tacgcatgtg tcatctagcg aactcatcaa aactaacaac
     4081 atatgcattt gtttctgtac atatgaatca ttatctagct ccttagctgc ttgaattgca
     4141 agcctgatat gcggataccc taatatcgct tcttcatatg caccatttac gccatatttt
     4201 tgcttcaccc tatgaccatg agtggttttt ttatgacgat attttgtatc aggaaaagca
     4261 gcaagcttgc tgacatcatc aagtattttc gataaagaaa aaggctgttc catactgatt
     4321 ttttgtgcaa tgacactgat caatagcccc attgcccaaa tcgctccttt atgggtattg
     4381 atgccatttg tagcaatcag cattgccttt tccgcttttc gcccaatctc agcaattctt
     4441 tctcttaact cctgatcaat agcatgatgc catgctattt gagccatttc ttcaaaaaaa
     4501 ggagttagcg tcttagcaga cttaagaaat aaagcatagt ccatatcgga atgtgcaccc
     4561 gcatccagtg catccactaa tccaggtttt ggacttaatg ttacttctgc gatcaatgct
     4621 tcctctacca acgcagcgag ttgctgagtc actgcttttt ttcgttcgtc atttatcatg
     4681 acactcactc cttcttccta ctattacttg ctgaaacctt ttttgatagc tacccaaatg
     4741 atatgaagta accagcttaa agcaaatgca caacttgccg tcattagata agctacaaga
     4801 atcatgactc ctgaaggtaa ctgcagccaa ctatctttaa acaataataa cagtacttgg
     4861 aaaacaaata cattggctaa atacgtacga taagcataaa cagacaacca tttgaacaat
     4921 ggcaattttg gcgaatcgtt tacaatcatt ttggaagcgc ctatgaagac agcaaagatg
     4981 atgactaaac tgtataaact ttggatcgta ttcaagtaag gtgcattcgc aaagctcaag
     5041 tctcctggat gtgcgagcaa tgaacggaca gaaaagaacg cgataactaa ggcaacaggt
     5101 aagaaaagat aacgtactct gtccaaatat tgatagactt tttcgtgata aacaaatgcg
     5161 gctaccccat aaatcatgaa actagcaaca aaccgatcta ataagtacca gctgtcatga
     5221 taaggcccag tcaatacttg tgtttgatag aacagatacc atgcgacata taaaatcgtt
     5281 gaaccaatca atactggcca tacatatttt ttattagcaa atactttgta accgagccaa
     5341 acaaaaaacg gcatgaacaa ttggatctgc agcatcataa cggtatacca taaatgaggc
     5401 gctccatcac ctgtgacata tttcagtaaa aagcttgcag tatccgtata cggagtttgt
     5461 tgttggactg ctggaaatag ccaaagataa gccgtcgtcc atagaagata cggaacgact
     5521 agttcaaaaa acttttcttt caaaaattcc caataagaca aatgctgact tgtttttacc
     5581 atattataaa caattgcaaa aataaacatt ggtgctgtgt atttaacgat gacgtaaaag
     5641 gtaccaagaa aagctgtatt tgttgcgctg tggctgtttg ccaaagcaaa gctcaatatc
     5701 gtttgcatca taacagccgt tacagctgat actttctgga agtcacttac gttgattttg
     5761 atttttttgt tttcaaacat ctctttctct ctctttttct ttattaccaa agttctttgg
     5821 ttaatttagg tccttcgact gttttcaata gaattttttt ctctggctct ctcaaatact
     5881 cttttagtga aaaaccgcct tgccgagtca ctacttgggt atcgaattgc tcaaaaaaag
     5941 caggatgcga ttgaattacc tgaattggca attcaatcgg tgaatttgcg tacagcagca
     6001 aatcaaaatc actggtttct tttactgccg gaatcccagt cgataattca aatcctaagc
     6061 tgccgccgat tccccattta catcctgata atatgtttct agcagcatga aattgctgat
     6121 aaacaggata atccatgatt ttctcttgtc tatacgattc ttgttcgatg atgtcccacg
     6181 gatgaatgac ttgtttgacg gcatgttttg agatttctgt tgaccatctc tgattgcggg
     6241 caggtccacg taaaccaatc ggtagtattt ctgcgtgatc cgtcgacgca cgacgaactg
     6301 ttccgaacat cttttcagtt agaacgaccc attcaggcaa ggtgaaccct tctatttcat
     6361 gtttatcaaa aaggacaata tcatgtgctt gaatcatttt ttatgcatcc cattcttcgt
     6421 ccattttggc acggacttta tttgtttcga cacgtccgaa tgttttggct atttcgtttg
     6481 tgtatcgatt tgtcagcatc gtgtcatttg tattgcggac atcttgaatg gcttcattga
     6541 ttgcttcgat gactttgctg acattttgtt ctgaagcagc ttggtcggtg atatcttcta
     6601 ggaaatgata gatcgctcct agttttgtat aattattgat atcgtaagcg atagctggaa
     6661 ctttttcagc agctgcttcg atttcagcaa ccgaacgttt tgtcacacgt gcagcacttt
     6721 ctttagacat cgcttggacg gtaatttctt tattgtttaa agcaatcaag cggcttgatt
     6781 gtaatccatg tgctaaaaat gcacctgaaa tagcatttcc tgcaatcaat ccaataactg
     6841 gatgtccagc ttgacggagt tttgcataag cagcagcact attagccaaa gccacatgga
     6901 taccgatcaa ttcttcgtta tagccgtatg cttggcttgg tacatcgatc acaacgatga
     6961 ttggccgttt cacttttttg tctttatctt cttcgtaaac gtgatccaaa atttgtccca
     7021 tgcggaaacc ttcaactaaa ccaacttcac cgtttcgtac acggtacatc gggtttttag
     7081 gatcaggtac gattgatgtc acgatggctt cttctatgaa tttacttgat ttaccataat
     7141 acacagtact aatagaagaa gttggatttt tcatgccagt tagtgccgca aaccaatcgt
     7201 aaccaacact tgctgcagct ggttcatttc cttctgctac ttctggtaag tcaattgatt
     7261 ttgcttgatg gttagcaatt gcttcattgt aatcgtcaat ggccattggt tttgaaagat
     7321 ctaaagaatc aagtaatgat aaataaaatg ctgagctttc actgcgatgc gtgtcttttc
     7381 gttcgtccat tgctgcgatg acagcagctt tgattgcttc tacactatca gtcactaatt
     7441 catcaatgat ttttgattct acccgttgac gagatcctaa tgtattccaa atcaagtctt
     7501 tgtcactaga atcaaattct cgaacgcctg cttcttgttc aataacttct ggtccattca
     7561 aaccgactct cgcttttttt gttgcgatta aataactcat taatgctgaa gtaatcgaca
     7621 taccgccaaa tgatcctaca cgtcctggaa tcaaaccgat gactggtaca tattgtttta
     7681 gagcaatgat tacatttccg atttctgaaa tagataacag tccgtagttt gcttcttgca
     7741 aacgaacacc acctgtatct agtacaatga ctggaaagat ctcatttcct tttttatttt
     7801 cttctaacac atgttcaagt gcagcaacga tttttgcacc ggaaacttca ccgataccgc
     7861 caccttggaa ttttccttcc atagcgatta ctactgcttg tttgccattg atcgtgccac
     7921 ggctgacaac gatcccgtca tcactttcag ggacgattcc ttgtgctggt aaacttggcg
     7981 cgatgatttg atcgaatgga tcaatcaatt cacgtccatt gtcaagtaga gcgttcactc
     8041 gttctctggc gtttaattct acaaaactat ttttcatctg aaagttcctc cattgcttgc
     8101 gtcaatcgta ggtacacaac tcctggtgta gcaccgaagt cattgatcac gatatctgct
     8161 gaaattggat aacgatcaaa aaatctcgtt aatacattgt tccatacttc gccgaagcca
     8221 tcgcttcctg tacaaatttt tacagtagat tctgtttttt ctgttggaaa catcaagatt
     8281 tccaaatctc ctgaaccgac cactcctaca tggattttct tattgatcgg ctgtttcgtt
     8341 ggatatttat aagctaattg ttccatggat ctctcccctt tttgtaaaac agagcataca
     8401 cgttctgctt attcgtcttt cttcttccat ctgggtaaat ggcgacaaaa ggtttttctc
     8461 gccaatttta tgaccaagtt ctgaatttca ttggtggttc atacaggcca tctgaccatt
     8521 cgatcaaatc atcgatggtt tgtgcagcta ataatgaacg tttcgcttca ctacgtttga
     8581 tgcctagatc ttctggtaat ttcacgatgc cggctgcacg caagctatct agtgattctt
     8641 tcgtgctagt cattccaaga ggtgtaacac cgccaattgc tgcaattgct gcttgtcgtt
     8701 cttcttttgt ttttgctttg tacaaataag caattccttc ttctgtcacg atatgtgtag
     8761 tatcttcgct ataaatcatc actggtgcat tggctaagcc tgcttgtttt tgaacagcta
     8821 gtgcatctaa ttcttcgaca aagactggtt ttttatttga accatatgtt tcaaccattt
     8881 gaacaactaa tttttggcct ttccctaatg gatcatcatt gtcgcgaagt gattgccatg
     8941 ctggtgtaga atgacgacga ccgccaggat tatgtcccat gttaggcgca ccgccaaaac
     9001 cagataaacg tccttttgtt acggtagaag agtttccttc gtaatctaat tgcaaggttg
     9061 aaccgataaa catatcgatg gcatattgtc ctgcagcttg tgataatgtt cggttactgc
     9121 gcatcgtgcc gtctttaccg acaaaaaaga catctgggcg agcagcaata tatttttcca
     9181 taccaacttc gccaccaaaa ctatggatgc tttcaaccca acctgattcg atggctggaa
     9241 tcatcgttgg atgtgggttc aatacccagt tcttcgcgat tttccctttt aaccctagtg
     9301 attcaccata agttggcagt aacaattcga tagctgctgt attgaatcca ataccgtgat
     9361 tcaaagattg tacgccgtgt tctgcgtaga ttcctttgat tgccatcatt gccattagaa
     9421 tttgcaattc tgtgatgttt tgaggatctc gtgtgaataa agcttctaat tgataaggtt
     9481 tatctgcttt cacgacaacg tctacccagt caccagggat atctacacgt ggtaaagaat
     9541 cgacaacttc gttaacttga acgatcacga taccatcttt gaaagctgca gcttcgatga
     9601 ttgttggtgt ttcttccgta ttgaaacctg tgtacaagtt gccgtcttta tctgctttat
     9661 ctgcagctac taaaacaaca tttggaatca aatcgatgaa taagcgtcca taaagttcca
     9721 aataagtatg gatatcacct aatttcattg tgccgtcttc aatcatttgg gcgacacgca
     9781 agctttgtgc accagcataa gagaaatcga tcttgcttgc gattcctttt tcaaaaatat
     9841 tcaaatgttc tggtcgtgag atactagaca tgatcaaatg cagatcattc actttttctg
     9901 catctacttt ttcaagactt tctgaaagaa aacttgcttg tttttgattg tcgccttcta
     9961 atacaacttt gtcgccggga gcaatcagtt tttccattac ttctacgatt ttttcagttt
    10021 ctacatactt gccattgagc aagttgctga ttttttccaa tcgctgcgct tttttttcgc
    10081 gtttagaagc ccagttgcgg tttggttttt ccataattag tcatctccat ttttgatata
    10141 gaaacgtggc gtcatcaata ccatgttggt ctagattgat cgtacggatc cctttatcta
    10201 caccaaattt tgtatgaatc agctttgtca aagtattgcc ggggggaaat tcaatcgtca
    10261 gatccattcc taattctttt gccaagtcca tcatttggtt ccactgcaca gggaaagcta
    10321 ggttttccaa caaatcttta cgaatctctt ctgcgtcctg agtggctctt ccatccgtat
    10381 tttttatata caaacatcta gcatcagata gatggacaga ctgcatatac ggcttgaatt
    10441 tcttgaccgt atcattcatc aagagacagt gagatggcac agggactttc agcagcttcg
    10501 ctgtttgcgc ttggtgccgt ttggcttctg ccaacgtaac ggataaacct tcgatactcc
    10561 cagataacgt atgttgcatc ggacaatttt catttgacag ataaactgga tggtcaggat
    10621 caaatgtttt tgctacaatt tcctcagctt cgcttctcgt cacacctact actacgccca
    10681 ttgcataacc gcttggataa gcttctttca ttaagactgc gcggtgatag actagttccg
    10741 ctgcattctc aaatctcaaa gatcgacaag caacagctgc acaaaaagca ccaatcgaat
    10801 gtcctgctgc aatatcaggc tgaataccgt ttttttccat ttcatctaaa taaaatactg
    10861 cttttgtcag taatgctagc tggataaaaa ccgtatcttg atagttttct tctttatcaa
    10921 ctaaccgata ccccgtcaca ttttctaaac gttccatgta catttcaggg atatccgcta
    10981 acatccctaa cttctgactg ccttgtccag gaaataagaa acctgtactc atgagcctcg
    11041 cctcctcagc acttactttt tccactgcta tcttagtcaa tttctgctat aataaaaaat
    11101 gccaaaaaaa gaaaaaacca taacaaaaag gtatggatgg gatggataat tatgaaattg
    11161 cttcatctgc agtattttaa aaaagtattc gaaacaaaaa atgttaccca agcagccaaa
    11221 gaattattta tttctcaacc tgccttgagc cgtgcgatca aacatttgga aaacgaatta
    11281 ggtgtccctt tgttttacca tagcggcaga aacattgaga cgaccgttta tgcagaagaa
    11341 ttttatccat atgcagtcaa gacattagac acattagaag aaggaatcaa attattgtct
    11401 tcggtcaatg agaagatcgt tacttccgtc atattgtatt tagaggtagc ctctgtttct
    11461 attccgaact tggtccgaat ttttatggaa aagcatcctg atatccaatt aacgatcatg
    11521 caacatcatt taccagatga tattaccgat cctgtactgt acatcacttc ggagatgaag
    11581 cctggcatga ccaatattcc tatcatgaaa gaacctgttt atgtcgccat tcctaagaaa
    11641 catcctcttg ctaaaaaaga acatctgcaa ttagaagata tccaacgcac ccccatcttg
    11701 atgctgtcaa agagcaacgc cttccgtcat acactggatg cagcacttga agcgaaaagt
    11761 atcgaattga cgatcagttc gacgacagat gatcctgcga cattacgttc tattgtcaag
    11821 caaggattag ctgttagctt tttcccaaaa gtttcttggt cttacgataa aaatgatcct
    11881 ttcgtcttgc gggaaatcaa agatttgccc ttgacacgaa caatttattt atcttctagc
    11941 ttcacagaag atcatccttt gatcaaaatg attgcaaaaa cgatgcggga attttattta
    12001 ggaaaataaa aaaaaaagag ctgggacaaa attcttgtcg cagctctttt ttcgaacaaa
    12061 cggtgttcca gaagtaattt cttagaaaat aagccgaaat ttcccaaaaa tttgagaagc
    12121 aattttcgta aattccttct tatttcttga agctaaacat ttctgtcaca acctcttctc
    12181 tattgtccta gacattcatt gcgttgattt aaaacttcca tcaatcaaat ctgctagttc
    12241 atctagcttt tctattttac gtagatcaat agagatccaa tgttctttat tcatgtgata
    12301 ggctggaaaa tacccctctt ttcctcgcaa aattccgcca agttcaggat cgaccttcaa
    12361 atcaagaata ttgatgatcc tatggtcact tgcatcatca tagatttttt cttctggaac
    12421 agacatcagg accccaaacc attttttgct tttttgatgt ctgaatacgc aataatcagg
    12481 aaatttttta aaaatatatt ctggagacaa attgtatgtt tcattgatgt gatcgattag
    12541 ttcttttttc gttagcatct gcttccatct ctttcttatt gattcgcttt attcaaagat
    12601 accacgtaag aatagaaaaa tgaatacaag tagttgctaa tcaaatactt cgatattttt
    12661 cttttttatc aactcttaaa tgttcaatcc gcctgtgttg gtcttgctac catctactat
    12721 taaaatgttt attattgttt gcccacctat tttttgattt tagtggtatc atttttcaag
    12781 ttcatgatga aattcttatc atcagtaaat gctccagaaa aataaacaat gattgaaaaa
    12841 tcagttgaaa cttgaccacc gtttattttc tccgtattct tagaatagaa gggagtctga
    12901 ttgatgtatt cactaatgaa aaaaatcatt accgaaaaag atattcgacg tcatgtttct
    12961 ttagtagaac aattgctgaa tcatacaaag ataaccgtaa atgaattagc tgaaatcata
    13021 gggacaaccg aacgaacgat tttttctgac cttcaatcta ttcgctctca gctgcccgaa
    13081 ggctgggaca tcatcagcga tcaagcagga atcagtttgc aaaaccagca aaatttatta
    13141 acaaatgacc tttgggagat ttttttcaaa caatcagtca gtgtcgaact gctgaaaaat
    13201 ctgcttttta caaaaaaagt tgctgtccct gattttctag ccgaccatgg gctttcttat
    13261 gggacattga aaagacatgt gactaaaatc aatcagcgtt tagcaagtta cgacttgcag
    13321 atcgatttga cgaaatatac agcttgtatt cttggaaaag agcgtgcgat tcgtactttt
    13381 tatcatcgat tgctgattcc tttcactcat aacaactatt ttttcgagga ttattcgatc
    13441 catgaatccc attattttca atttttaaga aacctcagtc aaactgaact agcggttgaa
    13501 acagaagaga ttttcggaac atgttggttc tttatcaata cgatccgtat aaaagcgaat
    13561 tgccgattag attcttctat ccataccaac agcacactct cctccctgta tgactctgca
    13621 ttgaaaaaat tgtatttaac ggaaggtatt tatcttaaag acactgagct ttcttttgct
    13681 tctttctgct ttctggaaag ttggaattac aacaataact atggacaaga aaccgctcgc
    13741 tgcctgcatc attctccatt tttagaggtc ctcgaaacgt ttgtagagga actagcttca
    13801 gagctgtctc ttgatcaact aaaaaaaaca tctctgactg ataacttggc tctcctcata
    13861 ttaaaatatc atgaatcgcc gatattgatt gaagcattgg accgtcaata ccatcgtttt
    13921 ttagaaacat atgatcagca atatgcacac ttgtatcaac agaaagagaa tttactgaac
    13981 gatctaaaaa aagaaataga aatcaatgaa ccaaattact ttctccaact cttgtctcta
    14041 ctgatccaac aaacgatttt ttctatcaaa ccgaatttgt tcaatgtcta ttttattttc
    14101 caaggagaac cttcatggaa ggcgttcttg cagcaggaat taaaagatta cttaggaaaa
    14161 cgtgtctgct tcttacctat cgaactaacc gatctttcca ctatttcttt tgaaaaaaca
    14221 gatatcttga tttccaattt ccctctagat tctctagata tccctattgt atacatttct
    14281 tctattccaa cgaaaaatga gctcaatcgt ttgactgaac tcactttcaa aactttttta
    14341 tagtaacggc tagcgactgt attctctagc tgttttttct tttttgcgaa acagtttgtt
    14401 catgatccct ttttctattt ctacaactaa gaatagaaga atcacatttg ctccaatcaa
    14461 taactgttgt gtcatcgtta aacttactgt accgatcagc tgctggccga ctggtagaaa
    14521 aataaccatc ccttgcaata aagcaaggat acctaatgaa agaaaaagcg ctttgttttg
    14581 caaaagacct tggttcaatg acggcttgga caactctctg caattgatca tgtaaacagc
    14641 ttgagctaag acgatatttt gcagaagaat ggtttgctgt aagctttgcc cttcaaactg
    14701 catagccaat aaataggcag gaaccatgat cagtagggag acatagatga tccgaaacaa
    14761 atgataacca gataggattc cttgctttgg atctcttggt gggcgcttca tgatttctgg
    14821 atctggcgac tcgaacccta gtgcataaga taaagtgatt gtcgttacca tattgaccca
    14881 taaaatctgt actggggaca aaggtagcgg gcgattcagc ataagtgccc aaatcaagat
    14941 caatccttga gctaatgcag ttggcaagaa gaaattgatg gttttttgca aattatccaa
    15001 aatccgccgg ccctctttta cggcttttgc aatcgtatgg aaattatcat ctcctaaaac
    15061 catatcagct gcctgtttgc ttacttcact acctttgatt cccatagcaa ttcctacatc
    15121 ggatcttttc aaagcaggtg catcatttac gccgtctccg gtcattccga cgatttctcc
    15181 atttttctgc aaagctttaa caattcgcag tttatgttct ggtgtcgttc gagcaaagac
    15241 atcgactatt ggcacttgct gaatcaactc ttcatcagac ataagatcca aatcgatccc
    15301 ttctaaaact ttggcagtat gttttaagcc aatttgttcc gcaatcgctt ttgctgtgtc
    15361 tttgtgatcc cctgtaatca ttttcactga gatccctgct tgttggcatt cctttacagc
    15421 tttgactgca ctttcttttg gcggatcgat caatccggcg atccctgcaa aagttaattg
    15481 ggttaaagtc tcatgcgtga gttcctgttt cgaatctact tttttataag caaatcctaa
    15541 aacacgctga ccttttctcg caaattctgc agctgtctga ctccatgctt cttgttctgc
    15601 agaagaaaga gttgatttag caaataatac ttctggtgca cctttgacgt aaatcaccgc
    15661 tcctttttcc tccgcatgca tcgttgccat atatttgtat tcagaactga acggaatctt
    15721 tgcttctatt tttttcaaag gtagattggc tgtttctgtg tgtcgaatca gcgcaacttc
    15781 tgtcggattg ccacttaaat tttctgtttt ctgttcttct tttgttttta attcctgaca
    15841 gtttttcata atggacaaca cgcaggcttc ttcttttgca gctacatcca caactgtcat
    15901 ttcatttttt gtcaatgttc ctgtcttatc tgaacagatc actgtcatag aacctaatgt
    15961 ttctaccgaa ggaagtcctt tgatgatcgc cttttctttt gccatttcat gtactccaac
    16021 ggatagaatc atggtcaaaa cagctggcaa tccttcgggt accattgaca ccaccaaagc
    16081 aatcgtagcc gaaagaagga tatgccaatc cataccatat cgaaatgtcg taaaaataac
    16141 taagaatagg ctcaaacaaa gaatgccttg aaaaatttgt ttgtttaatc ggttgatttt
    16201 tttaatcaga ggcgtcgttt gttgttcgac cgattgcaat gcttgattga ttttaccgat
    16261 ttctgtcgtg tttcctgttt ctacaacgac accgactgca gaaccagatt gtacaagcgt
    16321 tcctgaaaaa cccatatttt tctggtcgcc gatcgattct tcttctgtca aaacggcatg
    16381 acttttttca gatgcttctg attctcccgt caaaatcgat tcttccacta ataaatcatg
    16441 tgcttcgatt aatcggatat ctgctggaac gacatctccg gcacgtaaga caatgacatc
    16501 tccttttacc agttctttcg cagggatttt ttcttgcatc ccgtttgata gtactatcgc
    16561 ttcttgtccc atcagctgct tcaaaccatt caatgattct tccgcttttc tttcttgcca
    16621 gtaactaacg agtccattga cgatcactac gaataaaata atacttcctt caatatattc
    16681 actagaagca aatttcaaaa aagaggcaat gatcaacacg atcatcagca gatcagtaaa
    16741 atgctttgct atttttttcc atcgttttgt ctgctgcctt gcttttattt cattatatcc
    16801 ttgatcagtc aggcgtttct gtcgttcttc ttgcgacaag ccttctgttg atgtttgata
    16861 gtttttcaat acatcttcta ccgtcaatct gtaccagttc atcctatccc ctcctgttta
    16921 attgatactg ttattatacg cagggaagtt ttttcaggcg tatcgattat ttcagggggg
    16981 tctgaaataa ttcgttttgc aaaatgtatc tgggcctaac tgatatttct attgcttatt
    17041 cttttatata caaaatttaa gaatacaaac cagataacca ataaaaaagg aataaagcgt
    17101 gtcgtgcttt cgaataacaa gctgaaagca attgaagtaa aaaacaccaa caaagcaaga
    17161 tctttatatc tttgtgtagt gttccgtttc ttttctttaa taaattgaac atgtgcacac
    17221 aagatcgaag accacacaaa tagaaaacaa ctcgttgtca tgcctgccaa aagctgaaaa
    17281 aacaatcgac tatcagctac aaaaaaatgt agacaaagac cggcaaaaaa taacattcct
    17341 gtaattaaaa taccgtgtaa aggtacgcct ttcttagaaa gcgcacaaaa ccaatggggc
    17401 aaactttttt cttttgctgt ttgatataaa atcctgctag tactgtagac tgcactattt
    17461 gctgaggaca aagaagcaac caaaatcatt agattgacaa ttgctgctcc gccttggcaa
    17521 tggatcactt gcagcatagt cactaaagga ctttctttta aatctaaaca atgccatgga
    17581 acaacaaata aaatcgacaa aatcgttcct atatagaaaa agagaatacg ccaaggcaga
    17641 cagttgattg cttttttcaa attcttttgc ggatcacttg tctcgccaac ggttaagccg
    17701 atcatttcaa ttccagcaaa actgaataaa accataggaa atgagactac cattccagca
    17761 aagccaaacg gtagtaattc atcgatctgt ccaaaatttt ctttgattcc gatagactgg
    17821 gtatgaaaat ctgagacact caatcctata cccaataaga taaaaaggaa aatccccaag
    17881 atcttgatga ttgagaaaaa agattccaat tcaccaaacc acttgactgc aacaaggttg
    17941 actgccatta agatcattag tgcgctacct ccgcttatca aagctggtac atgtacaaac
    18001 cagaaatgga tatacaatcc tattgctgtt aattccgcaa gtccagctcc aagccagcaa
    18061 agccaataag tccaattgac aaaaaatgcc cactttttgc ctaaataata gtcaacgaaa
    18121 tcactgatag agttaaatgt actatttgct aaaaataaat cacccatggc ccgcatcaaa
    18181 ccataaatag ccaaaccgca tatcaaataa acgagaataa cagctggccc tgctgatgca
    18241 attgcctttg ctgaacctaa aaataatcct gttccaattg cgccacctaa tgcgattaac
    18301 tggatatttc gattagttag agtccgtttc attgccggtt tttccatcaa gttcaccttt
    18361 ttctttttca agcagcatgg cgacttcctg ttcccaagaa ggtttcttta ttttttcaat
    18421 acagagtggt actacaaaca aaatgacact gatggctgtg actgcaatta gattgatcca
    18481 tgttccagct ttcatcgtca gtccgacaga aaatccgatt gccgcaaata aaacaataac
    18541 gacagtccaa actccaagat tgctcttttt ctcttttttt ccaattctaa atggtcgatt
    18601 caactttgca tgtgtataac gcaatctcaa aactgcgatc cccatgatga catagacgat
    18661 acagtagata acagtagttg aatttacgag catcaaaaat gcttgattga cgccaggaat
    18721 cagcaaataa aaaagtgcaa agattgagat aatgacagac tgagtcaaaa taacggattt
    18781 ggatacgtca aattgattcg tcttccaaaa attgaatttt ggtggatacg caccttttct
    18841 agcactttct gtcactgtct ttgctggtcc tgaggcccaa gcagataatt ggactgctac
    18901 accaatgaag acaagtaaac taaacagatt cacaataaga tgtggcaaac caagaatttg
    18961 gcaataaatc gaaatagatt gcgcgatatt attcaattcc atttgtcctt ttggtacgac
    19021 atttgctaca actaaagcat tcaaaatatt gacgaaaaat ataaaaatta acgcggcaaa
    19081 tactccgcga atatacgttt taactggatt ttccaatcga gtgatataca cagaggacat
    19141 ttcgatacca gtaaaaataa acatgatcgg cgcaaaataa acaaatgagg atgcagtcgt
    19201 agtatctggt attaatttgt cccatgaaaa actgcctaat gttccggttg gtacgatccc
    19261 aactttgatc cacgcagcaa accctaataa gagcatcatc gtcaaaggca cgtacaatcc
    19321 taaccaaaca ccgacttttc cgccgatttt tgccatatca aatttcaaat tcaaaaaagt
    19381 gatgatccaa taaacgacta aaatgacaac taatgtaaat ttgctgttca aaccaagcgg
    19441 cacattatcg ataatattac caaacaacgg agcgagtgct gaagcgacca tcaccatccc
    19501 aggaaacatt tggacccata acagccatga gacaacgaac ccccattttt ttcctagagc
    19561 attcgatacc caaagttctg gaccaccttt ttggggaaac attccagcaa attcaccaga
    19621 gatcaatgag attggaaaag cgtacaataa tactgcaacc agcatgtaaa aaatcatcgt
    19681 ccagctcgtt gctgctacat ctggaatatt tcgtacactt gctacaaggg cgcaggtcat
    19741 tccgataaag gtcatggtcg tgatttgctt tgatgaacca gtatctttca tctttattcc
    19801 ttctttcaat agcgacatat gtttttgttt tcttttattt ttgttcaaga acagaaatga
    19861 caaggtttca tcgattcagt acaaaaccca gtatcaccga aacatccatt gaacgatctt
    19921 agtgaactgg gtttgataca tgaaacgaac gatccaactt atagaacgtt ttataaaaaa
    19981 gaatatcttg gcgaggaata tatgaaaaac agggggaaat acaattgttt tgatgaagca
    20041 aataattgtc tgttctccat atgtctcttg ttattctttc acacaaaaat cagttctatt
    20101 ggatgatttc gtttagtttc ttttccattg ctttggcgat tttttttgta taaaaattga
    20161 aaattcgatc atcattcaaa taaggagtca tgatagccgc acgtagcaga gtgattttct
    20221 gttctttttt ccattcttct ttcgttagac ccattctttc aacaaaacga atcggagaat
    20281 caccgtaatc ttcttgtgta aatgtagtat gagaagtaat aaaccgttca ccataaacat
    20341 cgccatccat ataagaagac cgatcgaaca ttttttcatt taattcattg atagcgttca
    20401 aatctgtaca gccttgttct ttgaataccc aattgaccat attaaaatca ggatgattca
    20461 atggatagac ttcgattgtt tttcctttaa cagtaaaagt cagatgatcg agaaattctc
    20521 tgaatctttg agctgcctcg attgaagccc caatcaattg accatatccg gtcacattca
    20581 atggcaatac acgatgtgct gtccagactg cggcggcggt tgctccagct tttgatcctt
    20641 ccaaaatata agctcctaac atatctggag cctttactga tttttcaaac acatatggcg
    20701 cgaaataaga aatgatattt ctcatatttt tatgtttgat tacgattcct ccagcagcat
    20761 aagggacata gcccatctta tgaggatcta tcgtgacaga atccgcttct gaaatagctc
    20821 tgaacccttc atatacctct ttgtcaatcg ttacgcagtg gtggaaaaca tgatgttctt
    20881 caaagaattc agctaaggaa gcatacggca caaattctcc tgcttcgttt agaaacagtg
    20941 aacgcgcata gccgccatat gcggcatcaa catgtaaata gaaatagatc ccttcatctt
    21001 ttaacctttc tcttaattgg acgattttat ctacactgtc tacttgacct tcttctgtcg
    21061 ttcctacgac agcaaccaca cctagaattg ggattttttg tccagctaat tcacgaattg
    21121 ttttttccaa agcattaata tccattcgat aatcctcttg aactgggata gcaaccatct
    21181 gatctaagcc gactccgcaa atatctaacg ccttcatcca agaatagtgt tttgtttgag
    21241 ggaccagcca tttccctaat ctttggatat tttttccgct acgggaagaa gctgctttga
    21301 cctcatccat ttcttcgtcc gtaaagcttt cggtcatttc caaaatttct tcaacagata
    21361 aattcaaaag ttcccactca gacatttttt tcactttttc aggcagcact tccttgacag
    21421 ctaaaggaat cgatttgatg caacgggcgt accataatcc ttcaagatta gcaatagaac
    21481 catctgctgc aatgtgtccc catccgtctg tcatattgaa taatgaagca aaatcctgtc
    21541 ctacttctgc ttccatttgc gaagttgcca tagaagattc caatgcaaca ttatttgggt
    21601 tccacagcat cgcatagttg taagctaata aagcaggcat caatgtttca gcattcattt
    21661 gtccccagta acggcctgct gaatgccatg ggatcgatcc tgcgcgtaat cgctgactga
    21721 cttcatccaa gacctctatc atatggtcgc gggtggctag ataatctgga gtgagcttat
    21781 ctccttcgct aattgcaggc atatctgaag gaatataatt ttctctccat ccaagatgtt
    21841 catctaccat cttgttcaac aacattttat aaactggtcc attttcagct ttgtcgccta
    21901 taaagacggc cttgatatcc atatctttca tttttcttcc ctccatattt tgttggtcaa
    21961 tgtcttgcag atacatgtgt ttatctgtaa cacctcttca ctatagcgcc aaaaatgaga
    22021 attttttttt tataacatca aatccacgta gatttttaca aacaaaaata aataaagtcg
    22081 gatttttctg ataattcaac gcaaaaaagc gaacaatttt tcaataaatc agtcttctaa
    22141 aatagataac ctaaaaaaag cgaacaaaca aataaaatga ctgtccttca ttcactaaac
    22201 atatttttat ttttttatat tgttaaaaat tcgcaattta ttttttaata gaattatctg
    22261 ttttccaaat tttataacat aaaaaacctt ttttaacggc atttatatgc tttttcagaa
    22321 attaactgat gatttcaaaa agaaaacatg tcataatatt tcccatattg tgcaaaaaaa
    22381 tacaaggcgg aggctctact atgattgaag aatatattga gaaaaatatt ttaagacagc
    22441 tgtttttatg tgggcaattc tatgtaaata aagaagtcaa tctagaaaag ctctccaatc
    22501 tcctgcatgt ttgcaaaacc actttactca atgatatcaa taacataaaa aaagaatttg
    22561 aagaacagat cgcttataca catcgggaaa aggaccgtta cactttatat ttttcagaac
    22621 atatacctcg atgcaagatc atgcagcaat tgtctcaaaa ttcgttgttt ttaaaaactt
    22681 gtctgcttta tttggaagaa gatgaacctg attatcttca attaactgaa tgtgaattca
    22741 tctctgtcag caaagcttat tcattaaaaa aacaagtatt agcttatttt aatgactgcg
    22801 ggatcgaaat cgaccgctac tcccctcgat tcactgaaat ggaaagacgt ctgctgcttc
    22861 ttaatgtgtc gtatcgttta ggcggtttta attcttggga gctacctgaa tcgttttttg
    22921 aacgtgccga tcgtttcatt gaatccgtaa cggaaaatag tggcagattt tatgataaag
    22981 aaaataaaga aatcttatcg attggttttg ctatcagttt cctacgccag caagtgtgtg
    23041 ctgtgacaat agattcaaaa tttatcgaag aaatcaaaaa acgtcctatt tacaattatg
    23101 tcgaatcagc atgggaaaac actgatttcc aaacctatta taaaaaagaa gaattcgcct
    23161 ttattttgac actattcaat ctttgtaatt atggtttcca ttcttatcag ttgattgcgg
    23221 aagactttca acagctacac caagtgttta ttgacaatac tcccgaaata aaagaactag
    23281 ttgctacctt tgaatctcac ttcaatcaag aattattcgg aaaccaaccg ttcgaacgtg
    23341 cgctgattca tctgatgcgt tcggcttggg ataactatca attattcatg ccagaaaaat
    23401 tttatctttt aaatgaggaa cagacaaatt tatataaaga agtccagaca attttttcca
    23461 gctggtccag ccagttacct tatgatctac ggttgaatcc taattgcatg cgggcttttg
    23521 tgatcgaatt gagcggaatt ctccgtctga caaaagaaca tctgactatc tatatcgtca
    23581 caaattcgga tgttcattat ctgatttatc gggaagcctt ggaagctgta actactttcg
    23641 attttcaagt tgcaccaaca atttattcaa gtatatctga tataaagaag tatgcgcagc
    23701 agtcctcaaa ccgggtatta tgtgaacgta cattatatac accagatgcg gtccaatatg
    23761 aaaatattat tcctatttcg atcaatacga tcgatcgagc tatcatttca gctgtgcaaa
    23821 acaaataagg ggctgtgaca aaaatcatgt cacagcctct tatttgttga agatgcccat
    23881 ttctgtaaca atctcttgat acacgtcagg ctcacaacct cacttatttt ggacatctac
    23941 gggtccgatc tctttattta aaaaataaga aatgatggtt cggataacta ccaacgccgc
    24001 tagttggaaa atatcctgca aggtaggttt gataatcgat tcgatgatcc cagctgaaac
    24061 aagaatttcc aaacttagaa gtatatagcc tcccaacatc tttttaatag cattgttctc
    24121 gctgactcgg tcgctttgca cttttgtatg gacaaataaa tatttcaaaa aatccttgat
    24181 tgatagacaa acaccccaaa ccaataaaca gatagcaaag atatcaagtc ccagtacaag
    24241 tttttcgaaa tatggaagaa gaaactgcat caactctgtc gtcatcctac ctctcctctt
    24301 ctttgttttt ctttgtcttc tatttcctga ttcaagaaat aagaaatgac tgttcgaatg
    24361 ataataataa gtgcaagctt caaaatatct gtccaagtcg gcttgataac tgactcgatg
    24421 atatcagcaa cgactagtac ttccaagctt aacaaaatat aacttgctag cagttttctt
    24481 gtatctgcat tacgagtatt acgttctgca tagtttttct tgacatgaga ccaatcaaaa
    24541 agtttgaata gaacaagaac gatcccgaca attaagatac cgatagaaca aatatttaaa
    24601 atagcaatga tccattctag aaattcaatt aaatttgagc gaaacatata cgctacctac
    24661 tttcttttaa tttgttccta ttcttttatt gtaaaagaaa gttaccttgt tcgtctattt
    24721 aaaagttgtt ctaatgataa cggttcgctt aaatttttct ttttcactct cccatttttc
    24781 tccctccatc cataaatcgt ggaagtatcc aaaacaacgt agcaagttaa aataaggctt
    24841 agtccgtcat cagcttttca aagaagcact gtctcggtgc tttttttgta cccaaatttc
    24901 taaaaataga accatacacc tcctcaaatc ttttcttctt acctacccta tttttattta
    24961 caggaaaatc agacacttct tcttttttgt caaaatttcc tttttcttct cgtcctatca
    25021 tttggcattc taataaaaac gaactatcct tggatataga aagagaaaac aaggaggcgt
    25081 ttttcatgag taaaaaatta atcaaagtcg gcatcggttt aggtttgctt gcccttggcg
    25141 ctgcatatct aggaaaaaag acaggactat tcgaagatga cagtcattta tatgatgaat
    25201 tcgaatcaat ctagcatcct atttagttga atcactacgg acatacttgg aagacattgg
    25261 aggaatcaca atgagaaaaa gtaaagcaat aatgattggt gccggtattg ccaatatggc
    25321 agcggctgtt tatttgattc aagaaggcaa atggaaaggg gatcagatca ccttttattc
    25381 attggatgat cacggttcaa atgatggtgc accgaccgac actgtagtgg atgaatattg
    25441 gaataaaaac catccattag aaaaccaaaa aggctatatt gctcgaggcg gtcgcatgct
    25501 taattaccgt acctatgtag atttgatgga tctgttaagt cgaatacctt ctgttactga
    25561 gccagggatg actgctgaag aagatacgag agattttgat gcaaaacacc gaacctttga
    25621 caaagcacgt ttgatggaag gtggcaaagg aatcattgat ggcggaaaac tgggattcaa
    25681 taataaagac cgtattcttc tgactaaact gattgctatg cctgattcag aagaagaaaa
    25741 actagacaat atcactatcg aagaatattt caaagatgat ccacactttt ttgaaacaaa
    25801 cttctggttt atgtgggaaa caacatttgc tttcagaaca cgtagttctg ctcaagaatt
    25861 gcgtcgctat atgcatcaaa tgatttatga attcactcaa atcgaacatc tagtgggcgt
    25921 caatcgaaca cgttacaatc aatacgaaag tattatgctt cctttgatcg agtacttgaa
    25981 agaacaagga tgcaaaatca ttttgaaccg ccgtgtcact gactgggaat tcaaagaaac
    26041 accgatgcaa gatgaaatca ctgtgactgg tttgaaaatt accaatacac tgactcaaga
    26101 agaagaatac gttgtggtcg atgaagatac agcagttatt ttcactaatg ggtccattac
    26161 agattcagct actttaggag attacgaaac accagctgta gaaaatatgg attatggtgc
    26221 agcttctagt ctctggaaaa aagccagtga acgtttctac aacttgggaa atcctgacaa
    26281 attctttgct gatcgagatg caagcgaatg ggtcagcttt accctgacga cgaaaaacca
    26341 tttgttgttg aatgaaatca cccgtatcac gactcaagaa ccaggaaatg ccttgaattc
    26401 atttatttca accacaccga tcacgccgtt aggccaaaaa gatgtcaata tgtctattgt
    26461 cgtgcatcat caaccgcatt ttacgtctca gaaaccaaat gaaacagtta tttggggtta
    26521 tttcctttat ccaagacgac gtggcgaatt tgtggataaa cagtatatta aaatgaatgg
    26581 aaaagaaatg ctagaagaac tgattggaca actttcaaaa gtagatcctg gaccagtgaa
    26641 tattcgtgaa aaagaaacag aaattttcga cagcgtaata aataatatcc ctgtctatat
    26701 gccttatgct tccgcgttgt tcaataatcg tgccaaaagc gatcgaccaa aagtcattcc
    26761 taaacattcg accaatctgg cctttacagg agaatttgtc gagcagcctt atcagatgat
    26821 ctttactgaa caaagtgctg tacgttctgg agaaatcgct gctttccatt ttgcgggtat
    26881 tcctatgtcc cgtcttgtca aaacaccgcg ttacgacaaa gatattccta ctctagctcg
    26941 tgccgcaaaa aaaatgtttg aataatcaag aggttgtgaa aaagctgccc tgcatcaagt
    27001 aataagaaca accaggctaa aacagcttct tatgtttttg atttggttgg acttattacc
    27061 gcagatgcaa gcttttgaac accgtttacc aagaggttat gaaaaagctg ccctgcatca
    27121 agtaataaga gcagccaagc taaaacagct tcttatgttt ttgacttggt tagacttatt
    27181 accgcagatg caagcttttg aacaccgttt accaagaggt tatgaaaaag gcgtttagtt
    27241 tcgagtatga agaaaaattt tgtgaaaatg gttcctcacg tttttgcata aatttgactt
    27301 aataccgaga aactgatccc ttctgtcata acctcttttt atttatgtct gtttcttttt
    27361 gaaaacaact attttttcaa cgtttactct cttgccaatc caacatcatc taacggatac
    27421 aactatttca atgattacca ttacactaaa aaatcggaaa cacacctctc cgaacacaaa
    27481 tacataagac tatagaatgt ttcatttaag aaaaaaagcg tttcattatc aaaaaggtaa
    27541 gatctccttt aaaatgaaat tatctgtagt actaataatg cagacaattt tatgaatctg
    27601 aaaggagcat ctccaatgaa agcagtcact tggcaaggaa aacagaaaat ggaaatcaga
    27661 aacgtagatg atccaaaaat attagaacca acagatgcaa tcatccgtat cacagcaaca
    27721 gccatttgcg gctccgatct gcatctttac catcatggtg aagcagtttt ggaaaaaggg
    27781 tatgttgtag gacacgaacc aatgggaatc gttgaagaag tgggatctca agttcaaaca
    27841 ttgaaaaaag ggcaacgtgt ggttatccct tttaatatta gttgtggtca ttgtcatttc
    27901 tgcctgaatc acatggaaag ccaatgtgat gaatcaaatc cagatcagtt atatggcggg
    27961 cttttcggat ttggcaagtt gaacggtaat cattggggtg gtcaagcgga atatctaaga
    28021 gttccttatg cagactctac ttcatttgtt gtaccagata atgatcttcc tgatgaaaaa
    28081 gttttatttc tatcagatat tttgcccaca gcttattgga gcgttgaaaa cgcaggagta
    28141 aaaaaaggcg atacagttgt gattctaggt tctggtccag tcggtctatt cgctcaaaaa
    28201 ttcgctgtta tggctggagc agagcgcgta atcgcagtag atccagtaca gcaccgtcta
    28261 gataaagcgg ctaattacaa tggggttgaa acttatttct tagaagacac ggcacaagct
    28321 ggaacagaat tgtatgaact ggctaaaggt ggcgcagatg tcattatcga ttgtgtagga
    28381 atggacggat tagagcctgt caaagaaaaa gcgaaaaatt tagtaagctt acaaagcggc
    28441 acaatctctc cattacagat ggcatcgcaa gctgtcaaaa aatttggaac agtccaagta
    28501 actggtgttt atatgactcc agcttcttct tacccgctgc aagaattttt tatgcgggat
    28561 atcgctgtca agcatggaca ggcaccaatt atccatctaa tgccaaaaat ttacgcaatg
    28621 attgcagaag gactattcga tcctacacaa atcattactc attcgctgcc actatcagaa
    28681 gcagcacaag catatgagat ctttgacaaa aaagaagata aaaatataaa agttgttttg
    28741 aaaccttgaa ttcagtaaaa aatacaggtg attttcttta tgcccaaaat caaacgaaat
    28801 acccatgaga tcgaaatagg aaaagaagaa gatatcgaaa tacgaggacg tcgcttccgc
    28861 ttctatttcc aaaatcgtta cacattgatc tcactggctg tcgatttatt aaccgggatt
    28921 ttctatattt ttggaagcct tgcttcctta actaaaatcc ccgatcgata tggcacctat
    28981 ttttatttgg ctggtgctat tttcttgacg attcgtccta ttctcagaat cgtaaggaac
    29041 atttttattt acgacgaaaa aaaagcaatg aagagaacaa gcaaaaaaaa agaggcatga
    29101 gaatttttca aatctcatgc ctcttttttc accctatcgt atcactttga tacagacgag
    29161 cggtcgtccc actttcttcc ttgaccattg tcaaaaatgt ccactcgtat cgttcataaa
    29221 acgtggtatg atctgtaatt aagtaaagtt tttcgtaccc aagttgatgc atttcttttc
    29281 tgatttccgc taatatccgc ttggctatcc cctgcttacg cttttccggt tcaacaaaca
    29341 gggcacaaag atttggtgtc agatcagggc ggttatggaa gtcgttttca atgacgcccg
    29401 ctcctccgac gatggtttct ttttcatcta agaccacata ccattgagga atactttcct
    29461 tattagcgat tccagtacga atactttcct catacacaac agcaggaact ccccattttg
    29521 atgaaaacca attcgcgctt tgttttacta attctgggtg ttctcttaat ttgatccagt
    29581 tatatgtaac caatgtttaa acctccgact aaaataaaac gtttacaaaa attatacaag
    29641 tctttatgaa aattagcaat gacaacaata gtgatgtaaa aaaaaaaacg gaaaacaatc
    29701 acttgttctc cgttttttga ttaatcaagc atctaaagct tcttttcttc tttcttggat
    29761 cgtagctacc ttgacgaacg gtagatagat caaaatagaa agaaccaaat tgacagcggc
    29821 tagtacacca cctgcaatac tttttgttgc caatacaccg ccaataattg gtggagttac
    29881 ccatggaggc ataacggtag ctgctggcac taaacctgta gaagtcgcaa agtaagcaac
    29941 actaactaag accattggtg tcaaaataaa tggaatgaac atgatcgggt tcaacacgat
    30001 aggtaaccca aacatcgttg gttcattaat attgaagaca cctggcgcaa tcgacaagtt
    30061 tgttacaacc atatatggtt tgtttttacg tcctactaaa taaatagcta acagtaaacc
    30121 taaagttgca
//
LOCUS       DBBGSZ010000031        30106 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.031, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000031 DBBGSZ010000000
VERSION     DBBGSZ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 30106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30106
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.031"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(27..1259)
                     /locus_tag="ACIZE5_001920"
     CDS             complement(27..1259)
                     /locus_tag="ACIZE5_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HGC6109043.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1514..2083
                     /locus_tag="ACIZE5_001921"
     CDS             1514..2083
                     /locus_tag="ACIZE5_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6109044.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2261..2701)
                     /locus_tag="ACIZE5_001922"
     CDS             complement(2261..2701)
                     /locus_tag="ACIZE5_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HGC6109045.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2859..3623
                     /gene="map"
                     /locus_tag="ACIZE5_001923"
     CDS             2859..3623
                     /gene="map"
                     /locus_tag="ACIZE5_001923"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HGC6109046.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3655..4578
                     /locus_tag="ACIZE5_001924"
     CDS             3655..4578
                     /locus_tag="ACIZE5_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HGC6109047.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4803..5042)
                     /locus_tag="ACIZE5_001925"
     CDS             complement(4803..5042)
                     /locus_tag="ACIZE5_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6109048.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(5047..5466)
                     /locus_tag="ACIZE5_001926"
     CDS             complement(5047..5466)
                     /locus_tag="ACIZE5_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HGC6109049.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            complement(5693..6931)
                     /gene="mef(H)"
                     /locus_tag="ACIZE5_001927"
                     /gene_synonym="mefH"
     CDS             complement(5693..6931)
                     /gene="mef(H)"
                     /locus_tag="ACIZE5_001927"
                     /gene_synonym="mefH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_070509550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide efflux MFS transporter Mef(H)"
                     /protein_id="HGC6109050.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            complement(7038..7673)
                     /locus_tag="ACIZE5_001928"
     CDS             complement(7038..7673)
                     /locus_tag="ACIZE5_001928"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6109051.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            complement(7787..7879)
                     /locus_tag="ACIZE5_001929"
                     /pseudo
     CDS             complement(7787..7879)
                     /locus_tag="ACIZE5_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323349.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(8015..8650)
                     /locus_tag="ACIZE5_001930"
     CDS             complement(8015..8650)
                     /locus_tag="ACIZE5_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6109052.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            9162..10304
                     /locus_tag="ACIZE5_001931"
     CDS             9162..10304
                     /locus_tag="ACIZE5_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGC6109053.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            10297..10503
                     /locus_tag="ACIZE5_001932"
     CDS             10297..10503
                     /locus_tag="ACIZE5_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HGC6109054.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            10582..11775
                     /locus_tag="ACIZE5_001933"
     CDS             10582..11775
                     /locus_tag="ACIZE5_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6109055.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            11980..13119
                     /locus_tag="ACIZE5_001934"
     CDS             11980..13119
                     /locus_tag="ACIZE5_001934"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HGC6109056.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            13112..13912
                     /locus_tag="ACIZE5_001935"
     CDS             13112..13912
                     /locus_tag="ACIZE5_001935"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGC6109057.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            13912..14739
                     /locus_tag="ACIZE5_001936"
     CDS             13912..14739
                     /locus_tag="ACIZE5_001936"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGC6109058.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            14744..15451
                     /locus_tag="ACIZE5_001937"
     CDS             14744..15451
                     /locus_tag="ACIZE5_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGC6109059.1"
                     /translation="MRSVCIATFNGGRYLREQLDSILSQLSAEDEVVISDDGSVDDTW
                     DILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWLETKVKKITD
                     YFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYIGAGMAFRSS
                     LKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIETHSKLRQKIS
                     WRVHLITALIKRKWFKR"
     gene            15551..16417
                     /gene="rfbA"
                     /locus_tag="ACIZE5_001938"
     CDS             15551..16417
                     /gene="rfbA"
                     /locus_tag="ACIZE5_001938"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HGC6109060.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            16431..17003
                     /gene="rfbC"
                     /locus_tag="ACIZE5_001939"
     CDS             16431..17003
                     /gene="rfbC"
                     /locus_tag="ACIZE5_001939"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HGC6109061.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            17025..18053
                     /gene="rfbB"
                     /locus_tag="ACIZE5_001940"
     CDS             17025..18053
                     /gene="rfbB"
                     /locus_tag="ACIZE5_001940"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HGC6109062.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            18151..19002
                     /gene="rfbD"
                     /locus_tag="ACIZE5_001941"
     CDS             18151..19002
                     /gene="rfbD"
                     /locus_tag="ACIZE5_001941"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HGC6109063.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            19036..21069
                     /locus_tag="ACIZE5_001942"
     CDS             19036..21069
                     /locus_tag="ACIZE5_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109064.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            21113..22393
                     /locus_tag="ACIZE5_001943"
     CDS             21113..22393
                     /locus_tag="ACIZE5_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HGC6109065.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            22603..23409
                     /locus_tag="ACIZE5_001944"
     CDS             22603..23409
                     /locus_tag="ACIZE5_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6109066.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            23421..24641
                     /locus_tag="ACIZE5_001945"
     CDS             23421..24641
                     /locus_tag="ACIZE5_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6109067.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            24631..26217
                     /locus_tag="ACIZE5_001946"
     CDS             24631..26217
                     /locus_tag="ACIZE5_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC6109068.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            26256..28394
                     /locus_tag="ACIZE5_001947"
     CDS             26256..28394
                     /locus_tag="ACIZE5_001947"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGC6109069.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(28762..29745)
                     /locus_tag="ACIZE5_001948"
     CDS             complement(28762..29745)
                     /locus_tag="ACIZE5_001948"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGC6109070.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
BASE COUNT         9619 a         5278 c         5978 g         9231 t
ORIGIN      
        1 ttttttgcat gtgtgcgaaa gtatactcaa gcccaatcgc catttcggaa aatcggtact
       61 gtagagccat cttcacggat tccgtcgata tccatcttgt cagatcctac catgaaatct
      121 acgtgggttt gacttctatt caatccagct tctgctaatt cttcatcgga catttctgta
      181 ccgcctttca cactgaaggc ataagcagaa cctagtgcta agtgattcga tgcgttttca
      241 tcaaataatg tattgaaaaa gatgatgcca gattgagaaa taggtgaagg gtcaggtaca
      301 agtgcgactt ctcctaaacg acgcgcacct tcatctgtat caagcagttt tgctaagaca
      361 tcttctcctt gttcggcaga aaaatcaaca acttttccat ctttaaaagt aaatttcata
      421 cccgagatga tggtgccagc ataactcagt ggctttgtac ttgaaatgta accatctact
      481 cgatgactgt caggtgctgt gaacacttct tccgtcggca tatttgccat gaatttttct
      541 ccacgagcat tatagcttcc agcgccttcc caaagatggt ttttaggcaa tccgataatg
      601 atatctgtac cgggagcagt atagtgaagg gcagaaaatt gttctcgatt caattcttct
      661 gctttttttg ctaatttttc atcatgcttc ttccatgcta agacagggtc ttcttcatag
      721 acacgagtcg ttttgaaaat ctgatcccat aatgcctcaa cttgtttttc ttctggcagt
      781 tctgggaaga cttttgctgc ccattgttta ccagccgcag ccacgacagt ccaactgact
      841 ttatttgctt gagttgcctt gcgtaaattc attagtgctt tgccattcgc tgattgataa
      901 gacgctactc gatggctatc tacaccagca aatgcatcgg gatcggcaga aacaacgctg
      961 atcctgcttg ctcctttttc aagccattca tccgcttgat cgattttaga ttgtggtaca
     1021 ttctcaatac gatccgttgc agcatgtaaa agaaattctc tttggatctg gtcgtcagtc
     1081 cattgaacga taacctcagc ggctcctagt ttataagctt cttgtgtgat caatcgagca
     1141 aggggtgcct gttccacgct gatctgtaaa acaactgtgt gtcctttttc tgtggctacg
     1201 ccagtttctg caattaagcg tgcatatttt tttagaagtt cattaaaatc agataacata
     1261 ataaaaattc ctcctcacca ttttttctgg taactattag catgatacca tttaattatg
     1321 attcaaacaa tgaggcttta aataaaaaaa ggaggttatt tttttaaggt taagtttcat
     1381 gatatatgtt actacttgct atttcagctt gtgaagaaaa tcaaaaacta attttgcata
     1441 tcaaaaaaaa catgttacaa tgaaattaat caatggtgga agcgttataa aaaaattaag
     1501 gagattaaaa aatatggcaa gaaaaaagac gattactaga gaacagattt tggcagctgc
     1561 ttatgaagta gctgccaccg atggatttac acgatttact gcgagaaaca tcgcgaacaa
     1621 aatgaattgt tccacgcaac cgatttatct tgagtttaaa aatatggatg acttgagaca
     1681 agctcttttt gagcagatct atgatcattt acaatatgaa gtgttcactg ttgagcatac
     1741 agggaatacg attatcgatc ttgcttttaa ttatatccat tttgcaagaa gagagaagaa
     1801 gttgtatcgt tcactgtact tagaagaata tggtggagga aaagagatgc agaatttctc
     1861 ttatacttac tttgtgaata cagtgaaacg cgatccagct tatgtgaatc tttcagaaga
     1921 gcagatcgaa tctttgtata atgggacatg gatcatagct actgggatcg cagctttgat
     1981 gtcttcaagc atcatccatc caactgatga acagattgaa aagatgatcc aagacagtat
     2041 agatgctatc ttgaaattca aagaaccaat cgaaatcgat tgaatatact caaaagttcc
     2101 acaaatcagt aggtaacaag agatgtgtca aaataaggaa aagttcgttt ttcttacagc
     2161 gtatgcattt ttaactcccg aagaactctt ccatgaatgc aatgaataaa agagccatac
     2221 agattgaata aatctggatg gctcttttat tgcaagtata ttaaattttt gcgactagtt
     2281 ctttagcgaa agcttctaaa ttttcgatat cttcttcttc agcattcaga tccactttaa
     2341 cattttcggc tccttttgat gcgcctgttt ttgcaaaagc agcatcgaaa tcatccaccg
     2401 atttgcagaa ttcatcgtaa aaagtatcac cagatccgca gacaccgtaa atttttccca
     2461 atagatccaa ttcttgcaag tcttcataaa agtctacgat ctcatcaggc agatcgccat
     2521 catcgtatgt ataagtagct actacgcaaa tatctgcctc ctcgaattca tctgcatcta
     2581 cttgggtaca ttcgttgatt tcgacttcga tatccagatt ttcaaatgct tctgcaacaa
     2641 tatcggcgat ttcttcagtg tttcctgtca tgctagcata tacgattttt gctaaagcca
     2701 tgatgtgcct cctcgtttat aattatttaa caattatgaa ttataccaaa acatcattga
     2761 aaagaaaata aaacctagag acacctgggg aatgtcattt ggctaaatgt atgccgctat
     2821 gttaaaatga gagggatttg taaaaaggag acgaaaatat gattacttta aaatcagcac
     2881 gtgaaattga aatgatggca gaatctggag ctttattagc agatgtacat aaaaatctgc
     2941 gtgattttat aaaaccagga atcacaagtt gggatattga ggtatttgtc agaaactata
     3001 tcgagagtca tggcggaatt gctgcgcaaa ttggctttga agggtatgaa tatgcgactt
     3061 gtatcagtat aaatgatgaa atttgtcatg gattccctcg taaaaagcct ttgaaaaacg
     3121 gtgatttggt aaaagtcgat atgtgtatcg atttgaaagg cggcatttct gattcttgtt
     3181 gggcctatgt agttggagaa tctacacctg agatcgaccg attgatggaa gtaacgaaga
     3241 aagctttgta catcggtatt gagcaagcac aagtagggaa tcggattggt gacatcggtc
     3301 atgctatcca aacttatgta gaaggcgaaa atctagcgat cgttcgtgat tttattggtc
     3361 atggcgttgg tcctacgatt catgaagaac cagcagttcc tcattacgga gaagctggaa
     3421 aagggttgcg gttgaaagaa ggcatggtta tcacgatcga acctatggtt aataccggaa
     3481 cttggaaaat gaaaatggat cctaacggct ggactgcgta tacaagagac ggcggacttt
     3541 cttgccaata tgaacataca ttggctatta ctaaagatgg tccaagaatt ttgacatcac
     3601 aaggagaaga aggcacttat tgatctatcc agtcaatagg tacgggagag gtacatgaaa
     3661 gtttggaaca aaataaaaca aaatgaaaat ctgatgcgct ttattgagac gactcaaaag
     3721 cgcatcactg attcagaaat gagtacgacc tctgtcgtcg ttgcttatta tttactcttg
     3781 tctttatttc cattgattat tgcttttggt aatattttac cgtttctcca catcgatcaa
     3841 gagactgtac tgacctattt acgagaagtg attcctgaga ccgtttacca gtttatcggt
     3901 cctgcaatca aagacctttt gacacaaagt tcaggaggct tgttatccgt ttctgcatta
     3961 gcggctttat ggtctgcaag tcaaagtatc aatgctttgc aaattgcgat gaataaagcg
     4021 tatggcgtag aaaatagaaa aaattttttg atcgtccgtt tcttctcact aattgtcatt
     4081 gtcttgttca tgattgctat tagtggggta actatcgttc ttgggttggg acagctgatt
     4141 ttggatgcta ttcagccaat cgtacaaata cccgtgaact ttatcgatca gttccaaact
     4201 ttgaagtggc caatcacatt ggtagcttta tttgtcatca tgttcttgat ttatttaatt
     4261 gtccctaatg ctcagttgaa gttgaagacg atcattccgg gcacgatctt cgctactgtc
     4321 ggctggatgc tgttatcaca agtgtttagt atctatgcta ggtattttgc aacgaggatc
     4381 agcggttatc agatcatagg aagttttatt gtactcatgc tttggcttaa ttttgctgct
     4441 acgatcatca ttttgggcgg aatcatcaat gcagttgttc aagaatacgt gacgggtcat
     4501 caaatcaaaa aacgtcgaga tccaagccga aaatggttca ataaattgaa aactaaattt
     4561 tctcataaaa aaaagtagaa acaagagttc ttattgtaaa tttatatcag taatttattt
     4621 gaaattttat atctaatttt caattatccg cataaacact atacattcaa gcattttgaa
     4681 gtatagaaaa acactcatct taccacgaat ttaccacgat tgaatgagcc ttgatatgac
     4741 cgtaaaacta ctaagggaga tagcacgaaa ctgtgtatct cccgattttt ttatacagtt
     4801 gattacttca ctccgatttc aaatttcaat attgctttca tcatgtctgt atgaatttct
     4861 ccttttagtt cttcatcaac ctgcataatg attttaccac tttcagagtg gtaaaaagga
     4921 cgcaagcata atttagaaat ataaccgtca taaaacttca aaatctcttt aactgccatt
     4981 tcatctccgc ttgacgcttt gcaaatcaat tcaaaagagg gatagccata atctttactc
     5041 atttctttac ttcctttcgc tcaaaagcat ttttaacttc cttagtcctc tagttcttct
     5101 actgcaaata gcagaacgtg atacatggta cagttctgaa atttctctgt cgttcattcc
     5161 ttgaaaataa cgtaataaaa tcgcactacg ctgtttttct gacagtctat gtaaaactgt
     5221 accaagtgtt tcatcagata cataaattgt aaagtgcaag actttaaatg atacacaatc
     5281 ataaaaacag gtatcaatcg ttccacgttc aacttgtttc gtttcggcta tttcacaaaa
     5341 caatacttca cgtttagaat gtcttgcaag ctgtctgttt cgacttttca ctttgttctt
     5401 aatgacaatc agcattaaag aattgaactg taatctgacg atatgctcga aagaagatgt
     5461 cctcataatc tcaccccctt tctgctaatg ctgaaatata taaacggaat accgtttata
     5521 ccctttagaa atacagaaaa atggtaagaa aaaagcccac acaaaacata tatttgtgcg
     5581 agccttaaat actgcaatat tactctttct tttataacac tatcctttta gcagatttca
     5641 aattttcttt tatatattgt ttttagccta acatactatt taaccccttg tattatatct
     5701 ctaacttttg aaaaattctt tttgaatata ttgaaatcat gattgaagca atagaagcta
     5761 caaacataac aacccatgtt tcttgtataa atacatcgaa taaaataccg taaaccattt
     5821 gtccaatagg ttgaccgcac atagcaactg ctaccagcgt agccattatc tttcctacta
     5881 attgcggtgg tgtttgtgtc tgaacaagag tgtaaatttg aacaacaaac atagtagata
     5941 cacccatagc cacaaagcac atcactgtaa ctacccagta ggaaactatt gcaggcaatt
     6001 ctaaaaatag cgaaattccc ataagtaaaa cagaaacaga acaaataagt aacaaggtat
     6061 aaaggttttt tagttttaac tttgaagcaa caagagctgt taaaatacca ccacataaac
     6121 cacctaatga taatgctgat tgtgaaaaac catatagtgt atctggcatt tttaaaactt
     6181 cagaaattaa gataggcaga ccaacaatta aaacagcact taaaaccaaa ttgaaaatgc
     6241 aaaccaaaaa gattacggat ataaaaatgg gtttctcctt tttcaaaaag gtataactat
     6301 cttttaaatc gtttttagca actgcaatta cacctacttc acgaggtctt ttttggtgtg
     6361 gaatatggat aaaaatttcc ataatggctg aaaaagtaaa acatataata ctaacaatta
     6421 aaatgggatt gataccataa aattgaaaaa ctactccgct tatagctggt ccgataaagt
     6481 ttgctaaagt atttacttga tttattatag cattaccgac ggtaagttta tctgatgata
     6541 ccaatagagg aatacttgct tgtaccgctg gttgatatgc accagaaata ccataaagta
     6601 acatcaaagc aacaataaac aaaggtatga taggaatttt tcccaatgac aaataaaata
     6661 ctaaaattat gattgctgtt acaaaatcta gtatgaccat aatgtttctt ttatttgtcc
     6721 tgtcagcaat aataccacct accagcgaca aaataaccat aggtaaaaaa gagcaggctg
     6781 tagcaatacc aaacaaagct gatgaaccag tttcttttaa caaatagtac ggtaatgcaa
     6841 atcgtaggat agcgtttcca aataaagaaa ttatctgtcc tataacaaca agtataaaat
     6901 cacgattaaa aagttttttt tctgcttgca taaaatctct cctttttatt taatcaaaca
     6961 gaccgtcggt ttatataatg gtttaaataa actgctcttt tatagagcag tctatcgtat
     7021 agggataaca aatacagtta tttacaaaac tgtataaatg cagaaattgt ttcttcgtct
     7081 aataatgtgt ctatgcctat tccatttaaa agggcattga atgtattgca acgtttttcc
     7141 ataccctctt tatccgtcat ttcaactaat gggttgagcc atacattact taataccatg
     7201 ataacttctg caatttcatg tgaattttca atctccaaag acttatcctt gataccttgt
     7261 tctaaaacgg gttcaacaaa ttcaggtact acaatttcat acatttgttc tatttgcata
     7321 gcaagaaaac gaggattgtt taatagttga ggagaaactg tcaataaaac gctttggtta
     7381 gaattgaata ccgctgtctt aaatatttct cttaactttt ctaaaccgtt taaactatcg
     7441 ttatctctaa ttttagcaaa tattactgca ttttcatttc caattctttg aaaaattgct
     7501 tttaaaatat cttcctttga atcgaaatga tgataaatag cacctttaga aagttttgtt
     7561 tcattgataa tatcttgcaa tgatgtgtta tcatatcctt tttcacaaaa catttttgta
     7621 gaaacatcta aaatgagttt tactgtttct tctggatatt tatttcgtgc cataacttac
     7681 ctccaataca aaccgttggt ctgattaaag tatatcttag tattttatgc ttgtcaatat
     7741 aaagacttgc aattttataa aaatgcagaa tgcaagcctt tttcatttat tctacaatct
     7801 tccagttgct ttccttatgc ggtgtcaatt catactgtga tacctgcgtt gcctttgcct
     7861 gatttaccac aaatcagatt ttatcccttt cttcctcttg attgcccaca acagaaaaga
     7921 aaaagccctg tcaagagctt tgccaccatt ggtggtgctt tgcactcttg atcgggcttt
     7981 ttgtttgctg tatcttctcg caagaggaaa aaagttactc gtcctcatca tcaaaattgt
     8041 tattccttaa tacttctcgt aacagttcca tatcttcttt tgagttcggg tttatcattt
     8101 tcacgacttg ataaggtgtc ttatacttat gtccctctat gctttcccca aacatatcca
     8161 tactgtataa atcatcatag cggtctaata atttttgaaa cttcaaatgc tggataaatt
     8221 ctttgattgg gtaaaggtcg gacgcttcaa tgcttttccc gttgatatag tctgtaatat
     8281 attcccgtaa cttttctaac tcatattcca gccattcttc ctcgctgtca aagaagttat
     8341 catagtgtcc atgtttcagt tctgcattta gacgttcttc ggctcttaaa aactgacaga
     8401 cttccttttc agattgattg acatacttcc attctcccga caacaattca ttgggcgtaa
     8461 cgtccagcac ttccattatc ttttccagcg tttcataggc aggatagttc aaccctcttt
     8521 caatcttgga aaggctctgc atattgatac cgattttgtc cgcaagttcc tgttgtttca
     8581 ttcccctaaa ttttcttatg gtctgtatat tatttcctaa atggcttatt ttcattgcat
     8641 aaccctccat atctcgttat atcttcgcta ttataagtct atcatgctta atatgatttg
     8701 taaaggcaaa aaaagatatt gacaaataag catataagaa ttactatgtt cttgtaatcg
     8761 aataagcaca atagaatgaa atataaaaac attcaaaaag aaatacctat ctgattaaat
     8821 ccgtagatat gaatatcggt tgaaatggaa cttgttagaa aaggcaaaac agaacttgct
     8881 gacaaagtat ttctgacacg gtggcggaag cctctcaggc ttaccgccat gacaccttgt
     8941 gtcaagggga agaaatgctt tgtcggctgg cgagcctgcg agccttgtct gtgcccccgt
     9001 tatctaacag gggggcacta tttcacaaaa gacaagtcaa aaaccataca cccccaaacc
     9061 tgtgagtagt aatgagaggt tttaagaaga tagtacatat cacacttttt gaaaggtggt
     9121 ttacaggtat ttcaaggcta ttgtgggatt ggaggaatac aatgaacaat ttagaatttg
     9181 cacttgaaat gaagaacaaa cgtcttgcca gcggtctttc acaaggagaa cttgcaagtc
     9241 ttacccatgt atcaagatat agtatcaacc gctttgagaa cggaaaagct aacgccagca
     9301 aggaaacaca gaacattatc ctgcgttgtc tgaattacta tatctgcgat aagccttttt
     9361 atctgctcgt tgattatctg tctgtccgtt ttccaacgac tgacgcattg gaagttatcc
     9421 gaaaggtgct tggcatgaaa gcagattatt ttatccatta tgactatggg tattatggct
     9481 ataaggagca ttatgcttac ggggaaatca aggtcatggc ttctgatgat gaacacatgg
     9541 gcgtattttt agaattaaaa ggggcaggct cacgcaacat ggaatatgtc ttacaggcac
     9601 agaacaggga ctggtattca ttcttaaacc gctgtcttga ctgtggcggt gttatccgac
     9661 gttttgactt ggcaatcaat gatatgtgcg gtctgctgga tattcctgtg ctatctgaaa
     9721 aatacagaaa tggtggtgcg gaatgtcgct gtaaaaacta tgaaaatgta caaggtggaa
     9781 aattaagcgg aaaaaaccgt aatttagcaa gtacccttta tatcggctca aaggcaagca
     9841 caaaatattt ctgcctgtat gaaaaacaaa aggaacaggc aacgaaaaag aaacataccg
     9901 atattatcaa ccgttttgaa attcgtctgc gtgacaaaaa ggcggtacag gcagttgaag
     9961 aactgttatt gacgtataac cctcatgggc tggtgtttta tctcattacc gattttgtgg
    10021 aatttcctga ctatccattg tgggagatat tcatttccca tgacagttta ccttttgaaa
    10081 tgaaccctgt acctgtcaat atggaacgca ctctgcaatg gctggaaaga caggtcatgc
    10141 cgtcaatcgt gatgatagag gaaatcgaca ggctgacagg ttcaaactac atgaaaatga
    10201 ttgatgaatg tacccacctt tctgaaaaac aggaaatgct tgtggaacag atgtgtacgg
    10261 acatatcaga cgtaatcgaa agtgaggggg tgttttatga gtaatacaca ggatattccc
    10321 gtatgggaaa aatacaccct taccattgaa gaagcgtcaa agtatttccg cattggagaa
    10381 aacaagttaa gacgattggc agaggaaaac aaggacgctg gctggctcat tatgaatggc
    10441 aaccgcatac agattaaacg ccgacagttt gaaaaggtta ttgataaatt ggacgcaatc
    10501 taatgcaaat gagccttgta tgtgttatga tgaacacaag tcatatcaag gctctttcca
    10561 acaaggaaag gagcagacac catgaaagaa aaaagacggg ataacaaagg tcgtatcctg
    10621 catactggag agagccaacg aacagacgga aaatacttat ataaatatgt agacgcattg
    10681 ggaaacacaa aatatgtgta tgcttggaga ttgacaccca cagacccgac accaaaggga
    10741 aaacgggaaa aaccctcact tcgagaactg gaacagcaga taagacggga tattgaggac
    10801 ggtatcgaca gcacaggcaa gaaaatgacg ctttgccaac tctatgccaa acagaacgca
    10861 cagaggacaa atgtgaagaa aagcacacag aaacaacggg aacaactcat gcggttatta
    10921 aaagaggaca agttaggtgc taggagcatt gatacgataa aaccctctga cgctaaagaa
    10981 tgggcgttac gcatgaaaga caaaggcttt tcctacaata ccattaacaa ccataaacgc
    11041 tcgttaaaag cgtcattcta catagccata caagatgatt atgtgaggaa aaaccctttt
    11101 gatttcaagc taagtgaagt catagaaaat gataccaaag agaaagtcgc attgacagag
    11161 gaacaggagc aagccttatt gtcatttatt aagacggaca acgtgtatca caagcattat
    11221 gatgatgtgc tgatactgtt aaagacagga cttcgtatct cggaactgtg cggactgaca
    11281 gtagccgaca ttgatttcaa gaatgaagtt gtgattatcg accaccagtt actaaagagt
    11341 aaggaacagg gctattatat tgaaacgcct aagacgaaaa gcgggataag gcaagtgcca
    11401 ttaagcaaag aaacgataca ggcatttcaa cgggttatca acagccgacc aaagataaag
    11461 tcgatagagg tagacggaca cagcggtttt gtgtttatca atccgaaagg taatccaaaa
    11521 gttgccattg attataacgc cttatttatc cgtatggtaa agaaatacaa caagcaccac
    11581 aaggacaatc ccttgccaca tattacaccg catacgctac gccatacatt ctgcacaagg
    11641 ctggcaagca agaacatgaa cccgaaagat ttacagtata tcatggggca ttcaaacatc
    11701 agtatcacaa tgaactggta cgctcatgcg tccatagata ccgcaaaatc agaggttcag
    11761 cgtctaatcg catagaagta tttaccacga ttttaaccac gattgacagg gaaaatataa
    11821 gaagatagac ctagatatgc gaggtttacc acaaaagcaa aatgcccgta gagccgataa
    11881 aataaggctt tgcggacatt tgagaagata taaaaagata gtcaaaaaga catatataat
    11941 ttataataat tatgactctt aattaaagta ggtgcccata tgcttgtttc ttttagtatg
    12001 gttataagat tttttctgac aattttatta tcactgatat taacacctgt attcaaaatc
    12061 atttcagtac aaacaggtat ggtcgacaaa ccaaatgaaa gaagaataaa taaagttcca
    12121 atgccttcag cgggcggact gcctatcttt atttcatttg ttatatcgac tttattctta
    12181 ttccgtaaaa ttatccctca atcgtatatt gtaccgatct tgattgcttc tttagtaatc
    12241 atagtcacag gagtgctcga tgataaatat gagctgacac ctaaacaaaa aagtataggg
    12301 atcttgattg cttctcttat tatttatttt gtagcagata tacgtattga ttccttcacg
    12361 cttcctttta ttggatatat ccaactaggc tggcttagtt ttcccgtaac gattttttgg
    12421 atcttcggta tcacgaatgc ggtcaatctg attgacggtt tggatgggct ggcggcaggg
    12481 atttcattga tcggtttaat tacgatagga atcattggat attttttcct ccatgcttct
    12541 acagtgtata ttccagttgt tattttctgt cttgtagcaa gtattatcgg tttttttcct
    12601 tacaattttt atccggcaaa gatttattta ggcgatacag gagctctatt cctagggttt
    12661 atgatggccg tcctttcact acaagggctg aagaacgtga cttttgtttc atcgatttct
    12721 ttgctgatcg tcatgggagt gccggtaaca gacacgtttt ttgctatcat taggagaaaa
    12781 gcaaaccgtg tttctttttc tacagcagat aaaaaacatc ttcatcaccg actaatcagt
    12841 ttaggcttta ctcataaagg tgctgtcctg acgatttatg cgatggcttt gatgttttct
    12901 ttcacagcta tggtcatgaa ttatactgga agaatcggaa cgatcatatt gattattgcc
    12961 atgttgtttg ctgcaatttt attatttgaa ttgattggtc tgatcaatga gaaacatcag
    13021 tttattttaa aaacattgcg atttttaggg aataaagagt accgtacgca agtaaaacag
    13081 aaatatttga agaaatggaa ccgtcatata gatgaataac aaattaaacc agccgatcct
    13141 tattagtatt gtgacggcaa acagtgataa aatttttcgg acactagata attttatttc
    13201 aactgtaaaa gatgaaacag cagtaaaaat ccgaattttt gacaacaatt cacttcccga
    13261 gtacaaaaaa agactaacag agtataggaa atatccctac atcgatatct attttcatga
    13321 tgaaaattcc ggatttggtt atggacataa tcacaatctg atagctagcg attctcgcta
    13381 tggcattatt tgtaacccag atattttagt ggatgaagag acagttacag cattggtctt
    13441 gttattgaaa gaacatccgg aatgtgcgat gttagcacct aagattctta atgaagatgg
    13501 aacaactcag cacctcatcc gtgagcagct ggctgttttt gattacgttt tgcgctttgt
    13561 gcctttcaaa tgggtcaaaa aaaagtttga caaacgactg gctgtgtttg aatgccgagg
    13621 attgcctact gatgctaata gttatgtacg gatgatctca ggtagtttta tggtagctga
    13681 tattgataaa tttaaagaga taaaggggtt tgatgagcgt ttcttcatgt actttgaaga
    13741 caacgacttg tgtttgagtt ttgaaaaagc aggttacaag ttattgtaca caccctttta
    13801 tgcagttatc catttttacg ggaagggtgc gcatcgaaat gcaaaactgt ttcgcgtgtt
    13861 tttgacttct atgatgaaat ttttcaataa gtgggggtgg cgttttttct gatgaaacca
    13921 gaaatattag tagtcgttgt gctttatcag caactattca gtcaatctcc agcttatgga
    13981 ccattaagca aagcacttag cgaaaagcaa attcagctta ttatttacga taatagtcct
    14041 caaaggcagc aaaatgagct gtttgaaaaa gaaaatatcg tttatcatca tgatccgcaa
    14101 aatcctggtt tagcggtggc ttataatttt gcgttgtctc aagcagatga aggaacacgt
    14161 tgtctcgtca ctctggatca ggatacgagg ctagtcgacg attattttga actattgcgt
    14221 aaagtaacct ttacagatga atgtgttgct gcagttccga tgattttttc tgggagccga
    14281 caagtttctc ccctatattc agatcgttat atcaatcgta cagctcaagc agtagaagtt
    14341 gaaggcccaa cagctgaacg aatcatggca atcaattcag gtgttgcctg gtctgtcaaa
    14401 tttctaaaaa agattggcgg gtttaatcct gctttttctt tagatttttt ggatcattgg
    14461 ctgttttgga aagtggatca gttggaaaaa actgtggaga tccttcctgt acgaatggaa
    14521 catgatcttt cggttttaga ctatgaaaaa gtttcaagta atcgataccg ttctatttta
    14581 caagcagaaa atcgatttta tcatgaatat gatcaaaggc atttatccag tcaccgacga
    14641 caattattgt taagaacagc taaacagttc ttgaccgtca aaaaccggca tatctggcgg
    14701 atgactttgc gctcatatgt taagaattgg aaggtgtgaa ttcgtgcgtt cggtttgtat
    14761 agctaccttt aatggaggca gatatttaag agagcagtta gatagtattt tatctcagct
    14821 ttcagcagaa gatgaagtag tcatttctga tgatgggtca gtagatgata catgggatat
    14881 attaactgaa tacgcagaaa aagataagcg aatccagctt ttttcggggc ctcgtcaagg
    14941 attgatcgct aattttggtt atgcgatcca gcagacgaaa ggagatctaa tctttttggc
    15001 agaccaagat gatgtttggt tggagacaaa agtgaaaaag atcactgact attttgagca
    15061 gaatccggat cagctagtag tagtttctga tttaatcatt gtggacagcg agctgcaaga
    15121 gatccatgat tcgtattttt cgtttcgaaa ttccaaagaa ggatggctta ataatgtgat
    15181 aagaagtcac tatattggtg ctggtatggc tttccggtct tctttaaaac ccgatatttt
    15241 gccgatcccg tcagaagtgc cgatgcatga tatgtggatt ggtttgctgg gaggaaagaa
    15301 gactgggttc ctaagagaac cgttaactct gtaccgaaga catgatttaa acgcgagtga
    15361 gattgaaaca cattctaaat tacggcaaaa aatttcttgg cgtgttcatc tgattacggc
    15421 gttgatcaaa cgaaaatggt ttaaacgttg ataaaagatg tttaaatcct taatatttcc
    15481 atgacaaata taacaattga tgagataata acaaagtgaa atttgaaatc aaaaaggaga
    15541 gcagatatcc atgaagggaa tcattcttgc tgggggcagc ggaacacgtc tgtacccttt
    15601 aacaaaggca acatcgaaac aattgatgcc gatttatgac aaaccaatga tttattatcc
    15661 aatgtctact ctgatgttgg cgggaatcaa agaaattctg attatttcaa cgccacaaga
    15721 tacaccacgt ttcaaggaat tatttggaaa cggaaatgat ttaggactgc agatcgaata
    15781 tgcagtacaa gaaagtccag atggattggc acaagcgttt atcattggag aagaatttat
    15841 tggagatgat agtgtctgct tggtattagg ggacaatatt tactatggtg gcggtctgtc
    15901 taaaatgttg caacgagcag cttcaaaaga tacaggcgcg acagtatttg gctatcatgt
    15961 caatgatcca gaacgctttg gtgtagtaga atttgatgag aatatgcaag ctttgtcgat
    16021 tgaagaaaag cctgctcagc caaaatcaaa ttacgctgta actggccttt atttttatga
    16081 caatgaggta atttctatcg ctaaaggtat caaaccttca gaacgtggag aactagagat
    16141 tacggatgtc aataaagcat atttggataa aggaaaacta tccgtagaac ttatgggacg
    16201 cggatttgct tggcttgata caggaacaca tgaatcattg cttgaagcat ctacctttat
    16261 cgaaacaatt gaaaaacgtc agaacttaaa agtggcttgt ttggaagaaa ttgcttaccg
    16321 tatgggctac atcgataagg aacaattgct ggcccttgca cagccattga aaaaaaatca
    16381 atacggtcaa tatttattga atttggccgc tgaataagga gtccttacag atgaaagtaa
    16441 cagatacaaa attaacagat gtcaaaatcg tagaaatgga cgtctttggc gatcatcgcg
    16501 gtttcttcac agaaagttat tcaaaagcaa aatttgcaga acatggattg aaatatgact
    16561 ttgttcaaga caaccattca ctatcagctg aagctggtgt ccttcggggg cttcatttcc
    16621 aaaaaggaga agctgcacag acaaaattga ttcgggtagt cactggagca gttttagatg
    16681 tagtagtgga tatccgcaaa ggtagcccga cttatggtca atgggacgga tttatcttat
    16741 ctgaacataa tcatcgacag ttgcttgtac ctaaaggata tgcccatgga ttcgttactt
    16801 tgacaccaaa tgtgaacttc ctttataagt gtgataatta ctataatgca gaagcagatg
    16861 ggggcatcgc atttgatgat ccagatttag cgattgattg gccaattgat ccatcaagag
    16921 cgattatgtc ggaaaaagat caccgtcatc cgacattaaa agaatttgaa gcagaaaatc
    16981 catttgttta cggagaaatc taagaattaa ggagaaattt tcttatgaaa aacatcattg
    17041 ttaccggagg tgccggattc atcggctcta atttcgttca ttacgtggta aacaatcatc
    17101 cagaagtgca tgtcactgtt ttggataaac tgacttatgc aggaaacaaa gagaacttgg
    17161 ctggacttcc tagcgatcgc gtagaattgg tcgtaggaga tgttgcagat gcagaattag
    17221 tggaccgtct agtaaaagaa gcggacgcag ttgttcatta cgcggcagaa tcccataacg
    17281 ataattcatt aaaagatcct ttcccatttg tacaaacgaa tatcattggt acgtatacac
    17341 ttttagaagc ttgccgcaag tatgatgtac gctatcatca cgtatctact gacgaggttt
    17401 acggcgatct tccattacgt gaagacctgc caggacatgg ggaaggcgaa ggagaaaaat
    17461 tcactgcgga aacaccatat aatccttcaa gtccatattc ttctacaaaa gctggttcag
    17521 atctgttagt aaaagcatgg gtgcgttctt ttggcttacg tgcaaccatt tcaaactgtt
    17581 caaacaacta tggtccttat cagcatattg aaaaatttat tcctcgccaa gtaacgaata
    17641 tcttaagcgg tattcgtcca aaattatatg gcgaaggaaa gaatgttcgt gactggatcc
    17701 atacgaatga tcattcttca gcagtgtggc tgattttgac gaaaggcaga attggcgaaa
    17761 cctatctgat cggtgcagac ggtgaagaag ataataagac cgtgatggaa ttgatcttag
    17821 aaatgatggg tcaaccaaaa gatgcgtacg accatgtaaa cgaccgtgca ggacacgact
    17881 tgcgttatgc aatcgattcg acaaaattac gggaagagtt aggatggaag cctgagttta
    17941 cgaacttccg tgatgggttg gctgacacga tcaaatggta cgaagaacat gaagactggt
    18001 ggaaaaaaga aaaagaggcc gttgaagcag catatgccaa aaatggacaa taatacagag
    18061 aaaatgtcac tgtattaatg gaaaaacaca tgtgaggcag gcgctcgcct gtctcttttt
    18121 taaaataaaa atcaaggagc ggataatcat atgtttttat taactggagg aaatgggcaa
    18181 ctaggtacag aattgcgcca tttattagat gaaaaaaatc tgcaatatgt ttcaacagat
    18241 gcaaaagact tggatatcac agatgccgag aaaacaatgg cttacatcac agaattaaaa
    18301 cctgatgtta ttttccattg tgcagcttac acagcagtag ataaagcaga agaagaagca
    18361 aaagaattag atgagaagat caatgttgat ggtacaagaa atgtagcact tgcagcaaaa
    18421 gctgtgaatg ctcaattcgt ctatatcagt acagactatg ttttcgatgg aaaaaacaaa
    18481 aatgtagaat acgaagtaga cgaccaaacg aatccactaa atgaatatgg tcgtacgaaa
    18541 ttattaggcg aaaaagcagt agaagagatt ttagaagact attatatcat acgaacttct
    18601 tgggttttcg ggatctatgg acacaatttc gtcttcacga tgcaacgcct agcggaaacc
    18661 cgcgacaaac tgactgtagt aaatgaccag tttgggcgac caacttggac acgtactttg
    18721 gcagaattta tggtatatgt catcgaagaa aaagcaccat ttggtattta tcatttgtcg
    18781 aacgaaaata gctgttcttg gtatgaattc gcaaaagaaa tattgaaaga tacagatgta
    18841 gaagttgcac ctgttacgtc agaagaattt ccgcaaaaag caacacgtcc gcagtattca
    18901 gtcatgagcc tgaaaaagac agaagagtta ggatttgtca taccaacttg gcaagaagca
    18961 cttgcgcaaa tgctggaagc tgccaaaaaa atgaataagt aatttccttt tatcaaatag
    19021 aatttggagc atgatatgga aaaacaaaca agaagtgcac gacgaaaaga aaagccaaaa
    19081 gcgaaccagg cagattcgaa tttggtgctt gacctgtttc taaaactccg ctatcttatt
    19141 ggcgttttag tcatcgtggt catcgttact tttaatttaa acggaagttc acttggtgtt
    19201 tgggataaat atgtgtcgca aagagacgat gggaaaaaaa ctgatgtgat ttttggacag
    19261 aatcgggaag tgcggtcaga cgaatggctg gtgcagacac ctttttacct ctcacaagct
    19321 gaagaggact ttccgttggt gaacgaggat tattcattaa acggacaaaa catgatcatt
    19381 gcgtataatt ctcctgtaaa ggatattacg gttatcggaa aaccattcaa ctggggattc
    19441 tttttcctcg gaagagatcg aggactttcc ttttattggg cgatgaaatt agtcgtcatg
    19501 gtcttgcttg gattcgaagt actgatgata ttaacgaaga gaaaaaaagc tctatcgcta
    19561 atcggtgcat ttgcgctgac attttctcca gcagtccagt ggtggttcat gcaacatgtg
    19621 ggcgatttga ttttctttac tttgggactg atgactgctt tttatcatta tttctacaat
    19681 catgataaaa aatggctacg aacgttgatg atgcttttgg tggttatttt cggtattggg
    19741 tttattttag tgatttaccc agcccatcaa gtgatgctgg cgtacttgct gattttttat
    19801 tttgttggcc tgcttattta ctatagcaag aaagtttcat gggatctgtt ggatgtagtg
    19861 ttgattggag gggcagtttt atttattggc ggagtcatgg ttcatttctg gctaacgtca
    19921 aaagacgcat tgttagcttc tttgaatacc ttatatccag gaaaacgggt aagtactgga
    19981 ggaaagtgga cgattggcga atttttttct ttccttacaa attggaaaat tccttttgaa
    20041 gatatcaact attcgaataa ctctgaagtg gccctgttct atcacttttt tccaactgta
    20101 ttcctagcaa gtccatttgt gttatttggc aaaaaagata gcgaacaaaa gttactggga
    20161 cgtattttga tgattttttg tctgttttct atcttttgga ttaccgttgg gttgccaaaa
    20221 tggctagcag aaatcactct gctgtcttat gttcctccat taagagccat ccttactttt
    20281 agttttgcgg cttgtttatt atcgatctgg tttatcgctt atatttggag agaagatgtt
    20341 attcctattt ggtataaatt cattttgttg gcagtaaatg catggtctta tttctatgcg
    20401 attacgcatt cgaaaatgga taattatttt tcggattttg aaaccatcgc agttgctgtg
    20461 ttgggaacag tgattttagc ttttgcatta tttggctgga gacgcttgtt ttacctcgct
    20521 tttgccgcct tagttatcgt atctggcttt ttcgtcaatc cagtcgtaga aggtacagga
    20581 gcgatttttg aaaaaacact ggcaaaagaa atccaaaaaa tcgatcaaca agatcctggt
    20641 aaagtttggt tgtctgaaga tgaattatat aacttcaccc caacattggg agtgaaatcc
    20701 ttcaatacag tacgctttta tccagatata gctgcatgga agaaaatcga tccgaaagaa
    20761 gaatacgaga agtattataa tcggtatgct catacaagag cttttatcgc taaggaagat
    20821 acaaagttca ttttagatcg tccagatatg ttttcggtca cgttgaattt tgaagacgca
    20881 gaaaaattag ggatcgacta tgtgatcagt aaacgaccat taactgatta caaccaatta
    20941 tatgaagcgc agttcacgca gctatatgga ccggataaag acggttatat gatttttaaa
    21001 gtagaatatc cggattatcc agatgtacca caaacacaaa ctcaggaaaa tcagctagtc
    21061 gtacagtaat aggctagctg agaataatcc tgaaatgtta gtagaaagga gagtggagat
    21121 aattcaagca atcgtacaaa aatttgtcaa caaaatgagt gtcggtttct tgcttttgtt
    21181 actgacgcta gtcttttttg tttggacagc agggttaggt tttccagcaa ctttgtttat
    21241 atataacaat agttcattac ttatcgcttt tagtgtggct attttgctca ttttaaatgt
    21301 ttataaagca aaaggcgtcg attttcttta tctaggtgtt gcgcttgccc ttttcatttt
    21361 cttttcttac tttcgggaat taagaaatga gtctttattt ggagacttac tgtttccttt
    21421 gattatttta ttttgtttag taattaaatg gatcgagtgg acaaaatggg atcgcggtat
    21481 ttatctgatt gtcttttcgg tcttcctcgg aatcacgtta tatcgtgtat ttacagagat
    21541 ccaagtacca gaaggacaaa gcatctgggc tccaggcaat tcgctttctg atatttggat
    21601 caatacgaat ataatcggaa gttctttgat gactcttgct ttattgatca gtggatttgc
    21661 cagttctttt gaacgatggt atgtacgaat catcggtgca gtagcagttg ttgcagcttt
    21721 tctcgggatt tgggtctgcc aatctagagg tgcattagtc gcgttgattg tttttgcgat
    21781 attggatctt ttacctaaat cgttgatgcg tgtcattcgt gcgccattta ttgcttacac
    21841 ggttacgatt cttttagctt tgccgatttc ttatctggcg gctgtctctg aaaaagtcaa
    21901 tttgtttacc ggtcgagaag atatttggca taaattctat cagacgctag gagaaaaatc
    21961 tgaacaaatt ttactaggaa tgaaaacatt tatcttccaa cgaggaaacc aatttttagg
    22021 aaaccacaat agttataatt ctattttgaa tatctatgga ttgataggat ttgggattgc
    22081 tgctttgctg cttatccttt ttattggtcg cttaacgttg aaagcagatt tatccaacgg
    22141 gcagatgact tttatctggg ccttttttgc ggtgatgatg cagtcattta tggaggatac
    22201 attgacttca tacccatggg ttccgattat ttatatcctg ttggctatgg ccgttcatcg
    22261 atatgatgaa ccagaagttg cggaggaatt ctatgttatg gaagaggcat atgacgatat
    22321 gacttatgat gatacatctt atgaggaaca accagatagc gctcattctt ccaggatcca
    22381 acgctatcat tgataggcac aaaatacgag agaggctgtg acaaccgtcg cagccttttt
    22441 tggtttattg caattgtcta gcatcttctg taaaatagaa acgttagaga aaatcttgta
    22501 tcatagaaaa ttaagaaaga aataagaacg cagctcggta ccaaaaatat ggtaaaatgg
    22561 cacttgactg taattcactg aaaatcgctt ggaggaacac aaatgtttaa agatttgtat
    22621 ttatttatga aggacattta tcagaacaga aaattattgc tacagttttc gatcaatgac
    22681 ttcaaatcaa gatatgcagg atcgttttta ggaatcttat gggcgtttat caatccgcta
    22741 tttactgtat tgatttattg gctggtattt ggtgttggac tgaaagcaca aatgatcgat
    22801 gcaaaatacc catttatcgt atatttagtt accgggatga ttccctggtt cttcttctca
    22861 gatgcatttg catcaactac ggttgttttt cgggaatata cttatttagt aaagaaagtc
    22921 gtattcaata ttcgtatctt gcccacgacg aaaatcctat ccaatctgta cacccactta
    22981 ttcttcattc tgattggcat agctgtcgcg cttataaatg gtatatatcc ttcagcaatg
    23041 tctttacagc tgatttatta tttattttgc atgtgtgctt tcttgacagg attgacttgg
    23101 ctgacggcat cgatccaacc atttttacct gatatcatgc aattaattac gatcgtgctg
    23161 cagttgatca tgtggacatt accgatatta tggagcccta atcagtttga ttcaggtctt
    23221 gtaagcatat tgaaattaaa tccgctgtac tatgttgttc aaggttatcg tgagtcattt
    23281 ttaagtgaag cttggttctg ggagcatgga acatatactt tgtatttctg ggttttcacg
    23341 ttagtaatgt tcgtaatcgg ctctgcagtg ttccgtagat tgaaaccaca tttttcagat
    23401 gtgctgtaag gagaatagct atgacagaat atgcaattag actaaaagat atcacaaaat
    23461 cttataatat gtacgcaaaa ccttcggatc gatttcgtga agccctcaat ccttttaaga
    23521 aatcctatca tgatgtattt tatgcgttga aaaacgtgaa tgtagaaata aaaaaaggtg
    23581 agatgatcgg tttcgtggga gaaaacggat cgggaaaatc tacaatgttg aaaatcatta
    23641 cgggagtact gacaccaaca tccggcacga tggaaatcga aggaaaaatc tcagctttgc
    23701 tagaactagg atcaggattc aatcctgagt attctggcta tgaaaatatc tatttaaatg
    23761 gaatggttct aggattttca agagaagaag tcgatgaaat ggtcgatgat atcattgaat
    23821 ttgctgacat cggagaccat atttatcaac ctgtaaaaac ttattcaagc gggatgttcg
    23881 ttcgtctagc ttttgctgta gcaatcaatg tgaatcccga tattttgatt gtggatgaag
    23941 cattggcagt aggcgatctt gaatttcaac taaaatgtat ggaaaaattt acagaaatca
    24001 agaactcggg aaagacgatt ttattcgttt ctcatgatat cagttcgatt cgtcgttttt
    24061 gtgatcgttc ctattggttg aaaaacggag aagtcgtcga atatggcgat acgatggaag
    24121 taacgacgaa ttatgaaaac tttttaaaga aaaaatcagt taaaacagtg gatcggaata
    24181 aaaaccaagt agaacggttc gccgctccag atatcgtcga cgtgacgaaa gcggaattgt
    24241 tggataaaga caaaaatccg gtggatatgc tggaacaagg agaaaaacta tacgttaaag
    24301 taacttatga agtaaaagat gatacaatca aaaatccggt tttaggaatt gcgctacgaa
    24361 cagtcgacaa tttttatgta tgcggactta atactctact agatggtatc aagattcctt
    24421 ggaaaaaagg agagaatatc ttttatctgg agtatgaaaa gttaggtttg ttagctggtg
    24481 aatattattt tgacgttgcg gtctttgaag aaaatgcaac ggttcctttg gtatataaga
    24541 caaagtacat gaacttgttt gtcagcggtt cttatatcgg agaaggcatc gtggtcttag
    24601 accataaatg ggaagaaggg actcatagca atgaaatatg attttgaaat ggacctagat
    24661 gaacaaagca gtgtgggaaa aattgccgca cagatcaaac caggaagtaa agttttagag
    24721 tttggtcccg gaaacggccg attaacgaaa catttaatcg gagcaaaaca atgtgaagtg
    24781 agcattgttg agttagataa ggaattgttc gattttgtca gcgaatttgc tcaagatgga
    24841 ttttatggtg atatcgaaag ttttgagtgg gcaaactatt atgctggaca gacatttgat
    24901 tacgtcttgt ttgcggatgt tttagaacat ttggtagatc ctggaaaaac attgaagaaa
    24961 gtcagagaat ttttgaatga agaaggagag atcctgatta cattccctaa cttggcgcat
    25021 aattctgtca tgatcgattt gttcaataac caattgccgt gggcttctta tggtctccta
    25081 gatgaaaccc ataattcttt ttatactcat gatggcttcc aaaaagtttt tgaaaaagcg
    25141 ggattattca ttaatattga agattatttg tacttagctg taggtgatac agaattaaaa
    25201 tcaacttatg aagaattgcc ggaagctgta cgctatgatt tcaaaatgcg accatttggt
    25261 gaagtctacc aatacttttt ctcattgatg aaacatccag tagcacaaag ttccattgca
    25321 gagccacaaa attctaatta tgtaaaagtg ttagaagtaa cccagcaaac gaaacaagat
    25381 gaaacaatcc aacaaatacc attcaataat ttcacagggg aaaatgagac actaagtttc
    25441 cccgtatcag aaacaacaga aagaatggtg tttcgcttcg cgcaacaacc tagctttatc
    25501 gaattcagcg cagaagctgc cggagaaaaa ctaacattta tcgattcgaa tgctgtagtc
    25561 aaaacagtaa atgattgtta tttgtttgat gggaaagaat taccagagtt cgttctaacg
    25621 gatatttctg ggaaagaagt gactatccat tgtcactatc gctttatcgg ggaattgaca
    25681 ccaacaatga aagaattgtt ggaaacgatt cgtcccatgg ctgaagtcac aaagcagctt
    25741 tctgagaaaa atgacgaatt agaaagagaa aatcatcatc ttcttgagga aaatacaaga
    25801 ctagaccata cgttaaaaac aaccacaaat cgctattgca cattgttgga aagtgatgaa
    25861 tggacaataa aacatagact aggacgacgt aagaaagaaa cttcgaaaaa aatccaagaa
    25921 aaagaacttt ctatatgtat tgacgagaaa atctgggatg cagaaacaaa aatattaaaa
    25981 atcatcggat ggggaatcgc taattcggat cgccagccct tgtcctataa gttatcagct
    26041 gaccaatcgc catttttcga agcaattcct gtttcacgag aagaagtcaa tcaagcagaa
    26101 cagctcgcaa aaggaacaga agcgggattt gagttacgaa tcctttgcga gcaagaacgt
    26161 tcattcttag tggaagcagt agctcaaaat ggccaatcat ggatcattga aatgtaaata
    26221 atgattaact tataaagata aggagtaaac gaatcgtgca aaaaaaagaa attgccgtat
    26281 ttatcgatca aatcactcgt gaacgggcca ctggcgattt gcttattgtg ggctgggcaa
    26341 ttgatgaagt gaccaaagaa atccctacga taaaggtaga aaaagaaaat gtgattgctg
    26401 aagcaacaca tgtcgtaaga ttggatatca atcatttata taatcttgat gttaagaccc
    26461 aaagcggttt taaggtacgt ttatcaggga aaatgagagg aaaagccatc ttagacttcc
    26521 aaacagcgag acatcaaaat ggcatagctg tgaaattaaa cggtaaatac ccttatgatg
    26581 acggcattga atcttcatgg gaaagaaaaa aaagattact gaaaaaaggg ataaattatg
    26641 caaggactca tggcgtaaaa aaagcgatcc gtcgggtcaa attggaattg aagccaggat
    26701 cgatcgacta tgcagagtgg atcagtcgtc atgagaaacc agatttgaaa gagcaaagga
    26761 aagaagcaca aggatttgcg taccgtccat tgatttccat acttatgcct gtctataacg
    26821 ttgaaatcaa atggctcgaa aaatgcattg attcggtact ggatcaaacg tatgatcatt
    26881 gggaactatg tatcagtgat gatgcttcta ctgatccagc tatccgaaag tgtctggaat
    26941 cctatcaagc aaaagatgat agaatcaaag tcgttttccg aaaagaaaat ggacacatca
    27001 gtctggcaac taattctgca ttggaaatag cagaaggaga atttatagca ctcttagata
    27061 atgatgatga attaccgcca tttgcattat atgaagtggc aaaagtgcta aacgtacatc
    27121 cagaactgga tgtgatctac agtgacgaag ataaaatcga tgcagatggc aatcgctttg
    27181 atccgcattt caaagcagac tggtcgcctg atacattgat gggaaataat tatatctctc
    27241 acttaggcgt atatcgaaca agcattgtta aagaacttgg cggtttccgt aaaggctatg
    27301 aaggttctca agattatgat ttggtccttc gtgtgacaga acaaatccct gcagatcata
    27361 tttaccacat tgaccgagtc ttgtatcatt ggcggacgat cccaggatca actgcaagta
    27421 atggcgaagc caaaagttat atctatgatt ccggagtgaa agcattgaca gatgccctgt
    27481 ctagaagaaa catcaaagga agcgtacgtc ctggcagaat ttctggattt tatgagattg
    27541 cttatgacgt cttgcaagag gatttggtca gtgtgatcat tccaacgaag aatggctatg
    27601 aagatctaaa aacttgtgtg gattcgatca tcgaaaaaac gtcttattca aattatgaaa
    27661 tcattattgc ggataacgga agtacagatc caaaaatgca agaattattt gcagaataca
    27721 agcatcagct gaaagaccgc tttatcgtag aattgattga cattccattc aattattctc
    27781 gaattaacaa tttagcagca gaaaaagcaa acggcaaata ctttttattc ttgaataacg
    27841 atacagaagt gattgagcca gattggatga cggtgatggt ttcttatgca cagtttgatc
    27901 gaatcggctg tgtaggagca aaactgtttt atccagatga tacaacgcag catgcaggag
    27961 tattattagg aatcggtggt gttgcagggc atgcattgaa taactatgat cgaacacatt
    28021 gtggttattt cggccgattg gtcattgacg tcaattactt agcagtcact gcagcttgta
    28081 tgatggtcaa ggcagctgac ttcaatgctg ttaacgggtt tgatgaaaca ttagaagtag
    28141 cattcaacga tgttgacttg tgcttgaaag tttatgaact gggtcgttac aatgtctatg
    28201 cacatcaagc agaattgtac catttcgaat ctaaatcaag aggttatgaa gatactccag
    28261 aaaaacaaag acgttttgct ggtgaaatca aaaaaatgca agataaatgg ccagcatata
    28321 ttgcgcatga tccattttac aatgataatt taacaaaaga aggaatcggc gacttttcgt
    28381 tgagaccaga ttaaactata ataaaaagct gttatgttgt gattcgctcg cacataacgg
    28441 ctttttatag ttttttgtca aaaaaaggca gaaggtgccg actcaaaaaa ataagtcgag
    28501 gttgggacag aagtgtttaa ctccgagaaa taagaagaaa ttcacgaaaa ttgcttttca
    28561 aatttttgtg aatttcggct tatttaagaa gaagttgctt ctgctcccac cgtttattcg
    28621 tttttaaaga atgagacaaa agtgtttctt acttttgtcc cacgctctta ttcatgctca
    28681 gagcgccaat agatacaaaa tcatagccaa agtttcacga accctagctg tcaaagaatc
    28741 gatattttat tttaatatag gctattttaa aataaatggt ttaaggtatt cctctacaaa
    28801 agccactcta tcaattatca tgggtttaaa ataagaagtg atggagataa ccagattgtt
    28861 cttagcgtca atataaagaa catttccact attaccaatt gctgaatata tttcgttctc
    28921 agaatctaat acccaccata aatagccata tctcatattt tgtaagtctt ctaaagcact
    28981 ggttctaggt ttgaacatct cgtttatcca catgggtggt acgatttgtt ttcctttata
    29041 catcccttta tttaggcata atacaccaat ttttgccaga tcacttgccg ataaacacaa
    29101 accatatcct gccgtcccga tatttagtgg atcacaaaac cagacattgg ttttaggaga
    29161 cttatccatt gtaaactgct tatgttcttc agctgtttca gcataataat tgacatggtt
    29221 tggtatccct ataggatcaa atagatactt attggcaaaa tcaacagttg ttagcttact
    29281 tgtctgatac aacaagccag ttaatatgtg taaacagaca gtttgatagt tgaattcgcc
    29341 ggttatacct tttcttcctc ccaataaatc tagtgatgtt tttgtccaat cttcacttga
    29401 acagactttt gtccatggat cgcctttaca tttgtagggt gctttcattg ttagcaagtg
    29461 cttgattgta atagcgtaaa tagttttctc cccgcgtttc actttatact ctggaaaata
    29521 atctaatact ttatcatcga tacttttgat taatccttgc tctaaagcaa tgccaatcag
    29581 caaagataca atacttttcg ttgctgacat gatatgacaa gtatcgtctt ttttataacc
    29641 attccattca tctgtataaa cttctacccc atccttatat gcgacaattt gacatatatt
    29701 tggttgtcga aaaccaataa aatcatgcaa ctcttgttta ttcataagat attacctcac
    29761 tttcttctat aagcataatg tcattaaaaa tcgatttcaa ttttttcgat tcttcacgta
    29821 atacaggtat tcttatggac tagacagcgc tttgggaaga tggattctct gaaaaatata
    29881 aaggttcact ttatgagtgg ataaaaaaag cagcaaatac ttcgacttct ttaatttacc
    29941 aacattagtg aaaatcgatt catctggaga tttgtaattt agagtccttg tcttgattag
    30001 aggtgtataa agctttttat tagacatttt taaattccat tacaatttgc ttataaacta
    30061 ggtttttaaa ggtgactatg gtaagataat agagatatta ttttgt
//
LOCUS       DBBGSZ010000032        29719 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.032, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000032 DBBGSZ010000000
VERSION     DBBGSZ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.032"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..833)
                     /locus_tag="ACIZE5_001949"
     CDS             complement(<1..833)
                     /locus_tag="ACIZE5_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC6109071.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     V"
     gene            complement(862..1179)
                     /locus_tag="ACIZE5_001950"
     CDS             complement(862..1179)
                     /locus_tag="ACIZE5_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGC6109072.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(1205..1525)
                     /locus_tag="ACIZE5_001951"
     CDS             complement(1205..1525)
                     /locus_tag="ACIZE5_001951"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC6109073.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(1989..3404)
                     /locus_tag="ACIZE5_001952"
     CDS             complement(1989..3404)
                     /locus_tag="ACIZE5_001952"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC6109074.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(3421..4737)
                     /locus_tag="ACIZE5_001953"
     CDS             complement(3421..4737)
                     /locus_tag="ACIZE5_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC6109075.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(4887..5585)
                     /locus_tag="ACIZE5_001954"
     CDS             complement(4887..5585)
                     /locus_tag="ACIZE5_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HGC6109076.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINGSIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(5874..6863)
                     /locus_tag="ACIZE5_001955"
     CDS             complement(5874..6863)
                     /locus_tag="ACIZE5_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGC6109077.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(6943..7776)
                     /gene="msrA"
                     /locus_tag="ACIZE5_001956"
     CDS             complement(6943..7776)
                     /gene="msrA"
                     /locus_tag="ACIZE5_001956"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HGC6109078.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(7951..9585)
                     /locus_tag="ACIZE5_001957"
     CDS             complement(7951..9585)
                     /locus_tag="ACIZE5_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-pyruvoyl-tetrahydropterin synthase-related
                     protein"
                     /protein_id="HGC6109079.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(9572..11260)
                     /locus_tag="ACIZE5_001958"
     CDS             complement(9572..11260)
                     /locus_tag="ACIZE5_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109080.1"
                     /translation="MKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLSRI
                     KGLSSIFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLLNI
                     CTILISFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYY
                     AYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFV
                     VVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDI
                     TTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLL
                     QFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVI
                     QSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKA
                     ADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIE
                     ITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            11406..13043
                     /locus_tag="ACIZE5_001959"
     CDS             11406..13043
                     /locus_tag="ACIZE5_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109081.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSKGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(13188..13928)
                     /gene="truA"
                     /locus_tag="ACIZE5_001960"
     CDS             complement(13188..13928)
                     /gene="truA"
                     /locus_tag="ACIZE5_001960"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HGC6109082.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(14119..14754)
                     /locus_tag="ACIZE5_001961"
     CDS             complement(14119..14754)
                     /locus_tag="ACIZE5_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HGC6109083.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(14901..16121)
                     /gene="sstT"
                     /locus_tag="ACIZE5_001962"
     CDS             complement(14901..16121)
                     /gene="sstT"
                     /locus_tag="ACIZE5_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HGC6109084.1"
                     /translation="MSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSCLKAIAPI
                     LVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPITLQETVSE
                     KAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSESTKELVDQI
                     SIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLFVALVVYP
                     FLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKESYSISIP
                     LGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGVAGGSLLL
                     IPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELGARKRSGE
                     KIKLKDCLDGLSER"
     gene            16340..17338
                     /locus_tag="ACIZE5_001963"
     CDS             16340..17338
                     /locus_tag="ACIZE5_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109085.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            17534..19369
                     /locus_tag="ACIZE5_001964"
     CDS             17534..19369
                     /locus_tag="ACIZE5_001964"
                     /inference="COORDINATES: protein motif:HMM:NF013080.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HGC6109086.1"
                     /translation="MQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFFFLL
                     LLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVSPVL
                     LIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHKNSP
                     SFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMKKYN
                     TKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTGGLM
                     LSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIAIHP
                     FTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQSNT
                     ETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAVKKF
                     IQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAATLNK
                     EVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVFVTE
                     DSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(19429..20145)
                     /locus_tag="ACIZE5_001965"
     CDS             complement(19429..20145)
                     /locus_tag="ACIZE5_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HGC6109087.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(20372..20914)
                     /locus_tag="ACIZE5_001966"
     CDS             complement(20372..20914)
                     /locus_tag="ACIZE5_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HGC6109088.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(20919..21146)
                     /locus_tag="ACIZE5_001967"
     CDS             complement(20919..21146)
                     /locus_tag="ACIZE5_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HGC6109089.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(21225..23105)
                     /locus_tag="ACIZE5_001968"
     CDS             complement(21225..23105)
                     /locus_tag="ACIZE5_001968"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGC6109090.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(23294..23908)
                     /locus_tag="ACIZE5_001969"
     CDS             complement(23294..23908)
                     /locus_tag="ACIZE5_001969"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6109091.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            24050..24610
                     /locus_tag="ACIZE5_001970"
     CDS             24050..24610
                     /locus_tag="ACIZE5_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6109092.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
     gene            complement(24915..25229)
                     /locus_tag="ACIZE5_001971"
                     /pseudo
     CDS             complement(24915..25229)
                     /locus_tag="ACIZE5_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
     gene            complement(25483..27118)
                     /locus_tag="ACIZE5_001972"
                     /pseudo
     CDS             complement(25483..27118)
                     /locus_tag="ACIZE5_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(27441..27920)
                     /gene="rlmH"
                     /locus_tag="ACIZE5_001973"
     CDS             complement(27441..27920)
                     /gene="rlmH"
                     /locus_tag="ACIZE5_001973"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HGC6109093.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            28348..29637
                     /locus_tag="ACIZE5_001974"
     CDS             28348..29637
                     /locus_tag="ACIZE5_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HGC6109094.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
BASE COUNT         9333 a         5751 c         4753 g         9882 t
ORIGIN      
        1 ttgacaaagc tgtcaaagaa aggtttgttc acgataaacg gtgcgctatg tccagctgcg
       61 attgcattaa cgtttgcttc aatggctggc gcattgattg tttgcatcaa aggatcgacc
      121 atattcgctc cgtgtaaacc aaagaaccat aagaatggtg tgataaatgc aagcagtaag
      181 gcagatggat aagagtttgc aagtcccata aatggttctt ggaccactgt atagaaagaa
      241 cctacgatat catcaacacc gaatgcagca aaaattgcag caactaaagc aaacgcagag
      301 atagtgatca ttgctggtag taatgaagca aatgcttttg caactgccgg tggcacacca
      361 tcaggcattt tgatgatcaa tttttcattt ccgcttaaac gtacaaagat ttctgttgaa
      421 ataatcccaa caataatagc aataaacaaa ccgtttgagc tcatacctaa tgctccgcct
      481 aaagcgaaga aagagcctaa agaaatcaca cctgcggaaa caccgtcttt tcggtagccg
      541 ttagctaaat gataagcaag caagaaagca atcaagacag aaagaatggc aaatgtaccg
      601 ttccaagcag cagccccgaa tcctttccat gattcaccac caaaaattga gttcatcaat
      661 tcttggaacc cgggaatcgg taagttattg atcattactg ctaatgctcc taagatcatt
      721 aacggcatac tcaccataaa tgagtcccga atcgcaacta aatgccgttg tgcaccaatt
      781 tttgatgcta caggtataaa atgtttctcc ataaatgcaa caaatttatc cataaatctt
      841 ccctcttttc tttactgtag attacgcgtt caatcgacga tacagatcaa tgatctcttt
      901 tgctaaatct gtaaaagcta tagatgtcat cagatgatct tgactgtgga ccgtcaaaag
      961 cgtgacttca acgtgatttc cttgtgcttc ttgtgtcagc atctctgttt gagagtgatg
     1021 tgcttggact aaagattcct ctgcatcttt gattttttca tctgctaaag tgaaatcacc
     1081 ttttttcgca gcagcaatcg cttccattgc atcgcttttt gcatttccgc caaacatgat
     1141 cagacccatg atggcttcta gatttttttg atcttccatt tattgtatcc tccgataatt
     1201 tttattattt gtttattagt ttttctgctt ggtcgagtac tttttcacca ttcatcatgc
     1261 catagtcagc catattgatt acatctaaag gaatgccttt aggtgctagc ttttcagcaa
     1321 attgattttg cataaagcgt acttgcggtc ctaaaagtaa aacgtctaca tttttagatt
     1381 ctagttgatt atccgcatct gaagcagata cagcaaagat gtctgcttcc attccttttg
     1441 cttctgctgc cttttgcatt tttgtgacta ggagacttgt actcattcca gctgaacata
     1501 caagcatgat tgttttcttt tccattttaa acacgttcct ttctatactt acacttgtat
     1561 ataagcaagt agcgtgccaa ctttaaaagc gctttaaaaa gttgatatca tcacatttaa
     1621 ggtctatacc aagttgcata cacactaaaa aagaaagcgc acactaaaca cacaaattaa
     1681 tttttattac cttttttctt ttaacgtgca caaaaaaagt tgtgacacaa aacttgtcac
     1741 aacttttttc aaataaacgg tattcaaaag cttgcatctg cggtaataag tccaaccaag
     1801 ttaaaaacat aagatgttgt ttttactttg ctattcttat tacttgatgc aggacagctt
     1861 tttcacaacc tctcaataaa cggtgttcaa tcagctgacc ctgggtatta gctcaaaacg
     1921 ctggattcac aacctctttt atttcaaata accagtaaat acaatgaaca tctacaaaaa
     1981 acttctattt atttatagat ttcgtcaggc aaatccaatt ctctcttatc aatcaaagtc
     2041 tgataccacg aagcagattt tttcaatgtt ctgcttcgtt catcgttcaa ttcgattcga
     2101 actaatccat atcgattctt aaatgcattc attggtgaca cacagtcagt gaatgcccat
     2161 aacatatagc cttcgcaatt tgcgccttct tctgttgctt tgatcaagta atgcaaatgc
     2221 tgtccgataa attcgatacg gtaatcatct tgcacgattc ctttctcatc catatactgt
     2281 tcttcatatt ctcttcccat accgttttct gttatcagcc aagggatatt atgataattt
     2341 tcttttagat acatggctat atcatacatg attttcggat agatttccca tcccctggaa
     2401 ttattcattt tcttcccagg taaatcaaag acttcataat atcgttcagg atggaaaggt
     2461 gtctcttcat tccattgata acgaggggcg cgaacgcgtt taggataata ttgattgatt
     2521 ccaaggaaat ctactgtatg atgctgaatc gtttctaaat cctctgttgc aggatcgaaa
     2581 taaatcgatt gtttttgaca caactccagg aactcttctg tgtagtatcc ttttaccatc
     2641 ggatcaaaaa atactcgatt ataaaacaaa tcatacatat aagcagcttt ttggtcttct
     2701 ggagaattgg atcgagcata gaccatttca ggatttaaaa tacagccaat ccttccacca
     2761 taatttccgc tgcggtaaat ctctactgct ttagccgttg ctaaaacttt atgataattc
     2821 cacatcatcc acttttttgt gttttgttca tgcggccagc gaacagcatc caaatagcaa
     2881 cgcgtttggg gaacgattgg ttcgttgaat gtaaaccagt tttttaccct atcaccgtaa
     2941 cgatcaaagg caatttgagc atacttagca taaaaatcaa ctacttttct tgaagaccag
     3001 ccatcatatt tttccaaaag aaaagctggg acttcataat gttccaaaca aatcatcggt
     3061 tctacgtctg cttcgatcaa agagtcgatc atttcactta tatgctgagc atattcttca
     3121 tctactatac agttctcata atcagtaaaa aaacgagccc aattgataga agtccgataa
     3181 tgtgtcagat ggatggattt catcagatcc acatcctgct ggtattgttc cataaaatta
     3241 gttgctacgg ctgggccata cccattatgc caaacaaaat gttcattttt ataccagcta
     3301 tctataaacg aatcctgtcc ttcttttttt cctttccaac cttccgtttg ccaagcagaa
     3361 gatgcagcac caagaataaa attttttgga atagtaattt tcatgatttc ctcctgtttt
     3421 ttagatccca tcattttcca cacgatttgc tacttttaca aatggcagat agatcaaaat
     3481 agaaacaata atacaaacaa gttgcgtaat aactgcaccg atatttcctg ctgttgccag
     3541 ataagcattg acgatcggcg gcattggcca agggaccatt acaactgctt tcgccgcaaa
     3601 tcctaaagcg gttgcaaaat aaccaatcgt tccagtgata agaggcgtta agataaacgg
     3661 aatagctaaa attggattca gcatgatcgg cataccaaaa ataactggtt cattgatgtt
     3721 gaagatccca ggagcaaggg ataacttggt gatttgtttc atatcttccc gttttccaac
     3781 taacaatact gcaatcagta aaccgatcgt gactccagac ccgcccatac tcatatacat
     3841 atcccaaaat ggcatagtaa taatgttcgg tacttctttt ccagcttcaa aagcttccgt
     3901 atttacagca attgccgcta aaagcaacgg ttcccgtatc ggcttcacca tttgatttcc
     3961 atggatacca atcacccaaa agacttgcgc aataaacatc aatagcaaaa tacccggtaa
     4021 cccttgtacg acaccttcta atgggcgttg tacgacattg taaatgatat cataaaggta
     4081 cattcctgta agttctttga tgataaatcc cgcagccgcg atacccgata cagtcagaat
     4141 cgtcgggaat aaagcagaaa aactagcaga aacattcgtt ggcacggtat caggcattct
     4201 cagctgtagt ttcttctgtt tcctcaacca gcaataaagt tcaatagaaa ggatggagac
     4261 caacattccc aaaaataacc ctttcgtatc tgtatattgt ttagccaata cgttttctac
     4321 tataacagtc tgattttcat tcactaattc ataaacagtt ggattaacag ataaataaga
     4381 catcactgcg atgataccag ggaatacacc atccacttta ttcagcttgg ctaattcgat
     4441 ccctatcaga aaaacagcat agatggtcaa gaaacttagt gtgacatagc tgatggcaga
     4501 tgcgataggc tttaattctt ctaaaaaacg caagaaactt atctgtgcta agccattttc
     4561 cgagtcaaag accattgctg aaaacaatgt gccaaaagca cccgtaataa ttaccggaat
     4621 caatgcagca aatgcgtttt ttatcaccat gatatacctt aaattattga ttctcgttgc
     4681 cacgttccct aaaacattgg ctaatttatc cataaaactc attccagatc ccctcattcc
     4741 tgcttcttct ccttgacgtc atctcttttt gtctattagt cagcgcttac atttcgatga
     4801 acagaaacta tttactcctc ttttttacca aatataaaac aaaaattcat ctgatgtatt
     4861 tatcataaaa tacatcagat gaactgtcaa ttagtttctt tttctcctat tattttctgt
     4921 aattctctcc gatttattgc catatggaca gtcattgcat caaacgcagc aagtgcattc
     4981 cgcctttcga tggcctgaac gatctctgta tgaatatcga tcgtctcgat tttcagatgc
     5041 tggatatcat aatttttatt aaacaaagca attgatccat taatgattgg gataatatgc
     5101 agcaaggcta cgtttccgct agcttctgca atcatcgtat gaaaatcgat gtctaattga
     5161 acatgttctt gtgtgccttc tcgaaaagaa gtttcaatct tttgcgttaa ttttttcatt
     5221 tggacgattt gattcttcgt tgcatattcc gctgccaaac ctgccatctt aggctccaat
     5281 aaatatctca gttcaaataa gtctcgtatc atccgatcct gatcttcaat caaagaaaaa
     5341 ccgagtgggt cattggcaat ccctcgctta tcactgacaa atgtccccgc tccttgccga
     5401 acttcaagga tattcctgga agctagagcc cgcacagctt ctcgcaccgt gcttcgcccc
     5461 acctctaaat aatcggacaa ttcatattca ttcggcagtt tatctcctac ttgcaactgc
     5521 atttccttta aatatctaag gatcttgtca gtagttactt ctactagggt tttattttct
     5581 tccaaaccac atacctcctt ttcatctgat gtattttttc gtaattatta taacacgttt
     5641 gaatcatctg atgatttttt gtatacaaaa ttgattaatc cgttcataga catacaaacg
     5701 aagaagatat ttaccataaa aaagactagg ataaaattca ctcctagcct tcgatcattt
     5761 ttattttgaa cgacaaaaaa tatgatgttc aataacagac gatcttcatt cgattcttga
     5821 tgtcatcttt tgtttttttt aatatatgga taaaaagttt gattacatcg tttctattct
     5881 agaatttggt cgattctcaa ttcttcttct ggtgagaaat ctaaattatc catcattcga
     5941 acactttctt gtaactgact taaccgactt gctccgacca gtacacttgt aacagatttt
     6001 tgtcgcaaat tccatgcaag ggccatttgc gctaatgatt gtcctcgtga tacggcgatt
     6061 gtttgcagtg ctttgatttt ttccagagtt gatccaactt gttcttctga aaggaatggt
     6121 atttccttac gatgtgctct agaatcttca ggaataccat gtagataacg atttgtcagc
     6181 aacccttgag caagcggact gaacgtgatt gcccctagcc cttcttcttc taatactgga
     6241 gatagatcgt cttctagtag tgcacgagaa aacatattgt agcgcatctg atgaataatg
     6301 aacggtgctt cctttctttt taaaatttca gtcatttttt ttgtatcttc tccattatag
     6361 ttggatatac caatatataa tgcttttcct tgtcttacaa gttgcatcaa agcttctgct
     6421 gtttcttcca aaggtgtatc agggtctggg cgatgatgat agaagatgtc aacataatct
     6481 agccccattc tttggagact ttggtcacaa cttgaaatga tggatttacg agagccccat
     6541 tccccatatg gcccttccca catatgataa cctgctttgc tagaaataat cagttcatca
     6601 cggtaggctt gaaaatcttc tctaaaaata cgcccaaagt ttttctctgc agctccagca
     6661 gggcctccat aattattcgc aaggtcgaaa tgggtaattc ccatgtcgaa tgcgcctctt
     6721 aaaatctctc tttgattatg gataggatca taatcaccaa aattttgcca taatccgaga
     6781 gataaaatcg gtaatttcaa acctgaatga ccggatttac gatattccat tttttcataa
     6841 cgtgcactat ctgcaatata caatttttct cctcctcatc aaatcttttt aaaacgcttt
     6901 cttttttcta tttttagttt actacatttt aaagaaaagg agttaatcaa aatgattttt
     6961 tcgtatattt ttttgccatt tgttttttac tcgttgatag atcagaaatt gattacgtgc
     7021 ttgctggatt tttttataac gtttcggttg ttttttgtaa aattgctgat gatagttttc
     7081 tgctggccaa aacgtaccgg ctggttcgat ttttgtgacg attggttggt ggaaagttcc
     7141 tgaactgtct agtttctgtt ttgattgttc cgctaattct ttttgtcgtt cgacttgata
     7201 aaaaatcact ggacgatatt gcttccctct atcttgaaat tgtccaaatg tatctgtggg
     7261 atcagtaatt tgccaataga ttgtcagcaa ctcgctataa cttatttctc ttgtgtcata
     7321 aatgatctcc acagcttcca catgacctgt gtaaccacca cttacttgat cataatttgg
     7381 tttttcaaca tgtccgcccg tgtatcctga caaaacagat aggatccctt ttttcgattc
     7441 aaacggctcg accatacacc agaaacatcc ccctgcaaat actgcacgtt cttgatagtc
     7501 agcatcttgc atggcatgct tggaaaagtc atatttttgc tccttatcaa atccttccgt
     7561 aatcaataaa taaaagtcca ttacatcagg cgtcagattc attcggatag ctaatggacg
     7621 tagtgttgct tctagttttg ataactgttc tttaacggat atattttctc ttatgtcatt
     7681 ctttgtctga atcaatactt ttcgttccca atctcgtgta ttcggattca aaatcagatt
     7741 ataaagtgtt tgaatgaata tttgttcctc atccatagat tctcctcctt tccgaagaag
     7801 acaagctagt gactttagct gtaatttatc ataaagtgag gaaataagcg attacttcat
     7861 ccccctacag atttttcgta taaaaaagag agaatcctta tcgacagatt ctccttttta
     7921 atcaatttat tttataaatg aaaagttaat ttacctttta tggaaaacta ttttaaaaaa
     7981 taaacataaa tatgcagtta atgtaacaag ataagaaata atagtcgtta ctgtataact
     8041 tgtgcttact ttaatatcag caactccttt gactccgctt atttgtacca atccattagc
     8101 attcacctgc tcctttacag gttgatgatt tatttctaca ttcgttccta aataagcata
     8161 tacaggaagt gtgattactt ggctcttctc attagttact ctatatatga tagaactacc
     8221 agttgtttta taaggaaggt ttacccattg actgccaatc tttgcttcgt gttttattat
     8281 atgctcctta ttctccaatg aagcgatagg agaataatca tataaaaaat aatccattcc
     8341 tttagtggta tacgcctcta ctgtttcttt gtttacaaca atatgtcccg gctgagaaat
     8401 tattttttga ttgaaatttt ttttactaga aacagttaaa gtgattaata acaaaacagt
     8461 cataaataaa taaaatagtt ctcttgtctt attgtatctt ctatttttga aaaatatcat
     8521 cgttaatatc agagaagaga atattatttg caagcttaag atccgccaag gaaattgtaa
     8581 caatttggct ggcgtatttt gcagaagata ccatggcacc aaactagttg tagctagcca
     8641 agtcaaacac gtaccataat aaatcttttt ttctatgttt gttaattttt taaataaaat
     8701 caggggaata cataaagata acagaccaac tagtcccatt gagtaagtag ttaagtcgtt
     8761 gttcatagct tcagtcagac tatcgaacac attagatgca tgagcatata aatttgtcac
     8821 gctaggtttg ttgatttttt ggtagagcat ttgttcaaac atcggatacc aaaaagcact
     8881 cgtcagaacc aatgtcattc ctgccgcact aaataatttt ttaaatatag caataaaatc
     8941 tgcattcttg aaacctttag aaaccaaacg aataaaaata aaaatgataa ttaatgctgt
     9001 actcattaat gttgatagta catggctgta cactagcaaa ctcatactca atgctagctt
     9061 tacagacgga tacttttctt cttttccaga gatgatttga taagcataaa ataatacagg
     9121 gataacaagt gttattgcga tagcttcggc aattgcggaa cgatagtaga tgtctactgt
     9181 ccgataagca gagaaaatat agagacaact aaataaaaat gccgcttttt tttgttttaa
     9241 aaaccgctcg ccataatgat aagctacgag tgttgtacac aagttcaata accaaacgta
     9301 aataatatag cttacaatca aattttttgt catccaatat aacattacag ctggaaaaaa
     9361 agtcagaaag ggataaaaat aatttacacc atatccagta taattgaatg tctcataatt
     9421 aatcggactg gtaaaaatag tcgataaccc cttgattcga gataagtgaa aagaaagatc
     9481 tccagtggta taaatactct gtgtattttt gaaaaagatg aaagaatata tactactaac
     9541 tataattaat ccactcaata ttactacttt tttatttatt ttcattcttc ttgtttatct
     9601 cctttttagt cacatatcga gaatctttca acttattagg tgcaaatcgt ttaaaacttg
     9661 aatacaccac taaacaataa gtcagaatac tgatccataa agccatgaga gcagttggag
     9721 tatattttgt tgtaatttct atcttatttt ctccagcatt tacatccaca ttcactaagc
     9781 catgtttttt ataagagtca tttacgactt taccgtttac ttttacctgt gtacctaaat
     9841 aagcatatac tggtactgtc actttttgct ttttgttgct tgccactgtg taagtaatgt
     9901 tattatctgc agctttatac ttcccttttt cccacgattc tcctactttt acttcatgtt
     9961 tttctaagtg aggcctttct tttatcgctt ctgttggggc gtaatcgtat aatcctccca
    10021 tatctgatgt tgtataacgt gggagtgttt cttcattgat aacaatatga ccgtgttttg
    10081 attggataac ttttgcgtaa ttttcttttg ctgctataga cgtgacgagt agaaacacca
    10141 cagtagcgcc aatgattaac catgaatatt ttttattcat agtctttttc ataaaaacaa
    10201 gcgttatgat cattgaagaa aaaaagattt ggatacctaa gatacgccaa ggaaactgga
    10261 gtaagcttat cggtgttttt tgaaacaaaa accatggaaa taaattagtt acgcataccc
    10321 atgtagaaac tacgccaaca tagatgattt tttctttttt ctccatttct ttcagtatga
    10381 ataaaggaaa aatcaacgca accaatccta ataaccccat agtgtatgtt gtaatatcgt
    10441 tatttaacgc ttgaatgata ctatctgaaa tagaaagtgc ttctagctgc aaatctgttt
    10501 tgaagggact gtgtatttct tgataattca tctgctgcaa cataggatac caaaaatagc
    10561 tagttaatgc acaagtcaaa aaaacagcct ttactaaatt cacgaccaca aattttatat
    10621 cgttttttat ttgcttgctt aaaaacaaac gaactataat catacaagca atcaatgcac
    10681 tacacaatag tgtagttaag acatgagtat acacaagtag acttatactg acagataaag
    10741 cgatgacttt tttttctcta ttgaatatca atccataagc ataatataaa acagctggga
    10801 taatcgtaag agcgattgct tctgcaattg cggatcgata atagatatca actgttcgat
    10861 aagttgcaaa agtatataaa caactaaata aaaaagcagc atctatcttt ttaaaaaact
    10921 tttctccata ataaaaacta atcagaatcg tacaaatatt taataaccaa atatatagaa
    10981 cataacttaa tattaagtta tttgaaattc cataaaaaac gactgcagga attattgtaa
    11041 gaaaaggata aaaatagttc agtccatctc cataattgtt aaatgttgta tagttgattg
    11101 gcccttcaaa aatagaagat aaccctttga ttcgtgaaag atgaaaagat aaatcacctg
    11161 ttgtataaat ttcttgagca tttctcataa aatttactga atataaagta ctaagtaaga
    11221 taagaactac taaaagaaat gcttttttac ttattttcat agatttgttg ttctcctttt
    11281 ttaattctat tttcagtata ctagaattgt ctttttttaa taagttttgc gttaaatttt
    11341 tcatagcact agtatgatat actagaaaag aatcaatttt tattactttt aaataggaga
    11401 aaaaaatgaa aaaaaacaaa aaccaaataa tagatatcat ttttatgtta tttctaagtt
    11461 ttgcttacgt catccctcta ttcatgtcta agggaatcta tcatagtgtc aatcaggata
    11521 cttactttca tttatctcga atcataggac tagataatgt atggagttct ccagtaaact
    11581 tcaataactt cgatcatcat ggaacaatga tgaatatttt ttatccatgg cttactcttt
    11641 atccagcttt tttattttat aaaatgatgg gaaatcttgt tttaagttat aatatctact
    11701 atttttttat cactttttta acaatggtcg tttcttattt ttctatgaaa caaataaaaa
    11761 acaatcgtta tatttcgctg ttattttcga ttatttatac attttccgcc tatcgtgcca
    11821 ttgacatatt ccatcgtgct tcattgggag aagctgtcgc tttaacattt ttgcctttga
    11881 tactaatggg gtgttacgaa atttatatta gagattacca aaaatggtac tggttgtcta
    11941 ttggcatgac gctagtagtg tatactcatt tactttctgt cgctatggtt tctgtattta
    12001 ttggaggaac gttgtttctt tctttttatt tttgggacca aaaaatcgct agactcttaa
    12061 gtcttttaaa agctaccgtc ctcacctttt ttttaagtgc gggattctta attcctttta
    12121 ttcaacaatc tagagcacaa gaattgaaag tcccactggg aaaagaatta agtggtatgg
    12181 ctcctagtga tatgctgaca catattttaa ataataacta taacaactat actattggat
    12241 tattcttatt tctcggattg attggtgctt ttatttttat aaaaaaatta actgctgatg
    12301 atttatttat tttctttctt ggtgtatttg ttcttttttg ttcaaccaat ttatttcctt
    12361 ggcaactttt taaccataca ccagttaaga gtctacaatt tgtctggcgg ttaaatggtt
    12421 tttcttcttt atttatagcc tatacgatga gtatagtgat ctattatatt ttttctacta
    12481 aaaataattc atggaaaata atggtcttta cgtttcttgc actaatattg catctctcag
    12541 gagtaagcaa ttctatccat gctaacaaag attcattaac acttatagca cctgaagacg
    12601 ctgttgctat agctgaaaat tacaatcata ctgattatgc aaacaaagag tcaatctatc
    12661 atcctgatat gattaataat gatcaatatt tactaggtaa ccaggaaata aatccaacaa
    12721 ctcattttat gagtaacaaa cttacaattg aattagataa ttcgaataat aaaaatactg
    12781 tcttgacgac acctatttat cgttataaag ggcaagtggc ttctattaat ggcaaactag
    12841 tacaaacaaa attatctaag tttggcacaa ctgaattaac tattcctcca ggtataaata
    12901 aagtcgttat tacttatcag tacacaaaac tagcaattgc ttcaagatat ttatctatcg
    12961 ttactttgat tttattttta ctttatcgat ttactttttc taaacaaaaa caaccgagaa
    13021 gagaagtaca acattctcac tagattttta tttaagaaag actttttagc tgtacacata
    13081 aacaggctaa aaagtctttt tttatatttc tttaatttgc ttcatacatt atttaacatc
    13141 gatatttata ctgtgaaaca tgcgtttcat ccattatcaa agtattttta tcgataataa
    13201 acttcatcca aaaacagacc ttgtgcaggg acggtttctc ctgcatgttg ccgcactttg
    13261 ctttcaaata tttcatcgat tgtttctatc ggcatggcac ctgtgccgat ttctagtaat
    13321 gtccccatga taatccgcac cattttatat aagaatccgt ctccgacaaa agtaaaatga
    13381 agcatttctc cctttcgttc gatagataat tcatcaatcg tacgcactgt ggattttttt
    13441 gattttttca atgcagaaaa accaatgaaa tcatgtgtac ccactaattt ttcgcaagct
    13501 gcattcagct tgtccatatc caactcttga gggaaataaa agctgtggtt tcgctcaaat
    13561 gctgaaggaa tcacgttgtt ccaaacataa tagctgtatt ttttgcccac cgcattatat
    13621 cttgaatgga agcgctcagg catttcttcg attcttttga tgacaatatc ccgcggaagg
    13681 taacgattca taaagtcgat catttctgcc agtccaattt ctgtgtttgt tttaaaattt
    13741 gctacttgtc ctcgcgcatg ggtgccagca tctgttcttc ctgatccaat aatttctatc
    13801 tcttcatttg tcatctgatg caatactttt tcgatttttc cttgaatggt tttatcgtca
    13861 tctccaagtc tttgccatcc tgaatatctt tttccgtcat attcgattgt caacttgatg
    13921 tttctcatat tttagtggct cctctgtctt ccatttggtc ttctctctac ctttttaaga
    13981 ttgtagcaca aaatatagct ccttgcttct ctaagacaga agctatacaa gaaaactgtg
    14041 gaaatatata tttcagaaaa acaaaaaaca gccaccggat gaagtatccg ctgactgttc
    14101 aatttgacgg ctcaagtttt actgtttgag atgcaagata ctcaaccagg caatgggcac
    14161 ataattaaag aaaaaactga ttctttggca aaaacctatt ttattcagta atggccaaga
    14221 atttatagaa ggaattcttg ccagtccata aatcgccgca aaaagcaaac tgatcacaga
    14281 cagtccaagg tataagtggc ttacgtccat ttgcccattt tttcgataga tcaagaaaag
    14341 aagaactgga aacaataaaa aaccactgta acctaaacct gatccgatat tatggaccca
    14401 tgtcgagaca ttccacgaag attcatgggt attgatactg aacaaacctg taaagataca
    14461 atcacctata ccatagaacg cgatggctgc tgtaactagg gtagctaaca cacgagatgt
    14521 actaacaaat gcagcataca atgcaggcaa tgacaggatg aaaaagatcc ctgaaaccac
    14581 agaccaaata agaaacgctt ttcttacagg actggaaacc tctccaaata cactgatcac
    14641 gctcttcatt tgatctaatt caggataata caatcctaat acgtacggag tcaaaaaatc
    14701 actcagcacg cctaataata aaaagaaaaa accaaattta cgtaaaaaat ccatgatacg
    14761 cctccaataa caattaccta tgcttttaat tgttattata aacgacttta tcttgattta
    14821 acagaaacct ctatttacac gaacatctat ataactcatt aaaaactcga atcattttaa
    14881 aaatactaaa tatctaacgt tcaacgttca cttaatccat ctaaacaatc tttcaatttg
    14941 attttttccc cacttctttt acgcgcgcct agctctccta ttgcagtaaa caacagatca
    15001 cttgacgaat ttaaggcagt ttccattgaa tcctggataa caccgataat aaatccaata
    15061 ccgacgattt gcatcgcgac atcattagag ataccaaaca aactacatgc taatggaatc
    15121 aataacagtg aaccgcccgc aacacctgaa gctccacaag cagctaaagc agacaaaata
    15181 cataaaagga ctttcaaaac aaaaggtgct tcaatcccta aagaatgtac agcagtcaac
    15241 gtcatcaagg aaatggtaat cgcggcaccg cccatattga tcgtagcacc taacgggatc
    15301 gatatggaat aagactcttt tgtcaatttc aatctttcag ccaacatcat gtttatcggg
    15361 atatttgcgg cagaacttcg ggtaaagaaa gcgggaagtg cgctttcttt caaacaaaag
    15421 aaaatcaatg gatagggatt ttctttaata aacaaaaacg tgaggaatgg gtacacaact
    15481 aatgcgacaa acagcatcgt accgatcaaa acaagtaaaa gctgcagata ctctgccaat
    15541 ccagcgattc cagtcgtagc aattgattga taaaccaatc ctaaaatccc tatcggagca
    15601 aatgcaataa tcacttgtac gacttgtgac aacgctatag atatctgatc caccaactct
    15661 tttgtcgatt ctgaacgtgc tcgaaaagct agtcccaaca atacagccca gaataagacg
    15721 ccaaggtaat tcgcatcaat aagagattga acaggatttt gtgtgacatt cgtcaacata
    15781 gtagataaaa cactttccaa actttgcggt gctttttcag atactgtttc ttgtaaagta
    15841 ataggaacag taaaaattga acttacaata actgctacaa gtgcagaaag caatgttccc
    15901 actaaatata agatcaaaat aggcttcacg aatgtcttat tcccaatttt atgcttggca
    15961 attgacgcca tcgtcaagaa aaaaaccaga ataggtgcga ttgccttcaa gcaactgaca
    16021 aacaacgttc ccaatattga aataaatgtc catgtgggga aaaagatacc aaacaatatt
    16081 ccgactaaaa taccaacaac aatacgttga actaacgaca tatccaaaaa cttctctaac
    16141 aaatgaccac cctttcacaa ttttaacaat cattgtatca ttttatgcaa agaaactaaa
    16201 ggtataattt tctaaaaatt ctaacaatac aaacaaccat ttcttgctaa ttttgtactt
    16261 tttctgtcta cacgttgttt tttgagatat tctaagttag gatgttatta atgggcaact
    16321 tatcaggaaa cgttttctta tgtttttgtc caattttttt gtgaggtgtt tattcttgaa
    16381 aaaaataaag aaggagagtt atggcttcct gacaatcttt gtcgcttgta taatgatggt
    16441 tttacagcgt atattgattt cagcagtcac tattcctaca tatgcaacaa accctggtcg
    16501 attctacatc tatacatttt tacaaacttc cgttgttatt ggtgcaaatt tgatcccact
    16561 ttacatgggt taccaatatc aaaaaatcgc ccgtttaaaa gttttacatt atttaagtcg
    16621 ttttgccttt atattcctaa tagccacact agtttgcaat atcttttttt acgtacaagc
    16681 tggcagcttg aatattcgtg attattggct tatcctaaca cctatcagtc agaattactt
    16741 tacttatgct gtttcttgta ctttgctttt ttgtagtatt ccttatacag ttggattttt
    16801 aaataaatta tcgaaaacaa caattaaata tctactatta tttttaacaa ttggattagt
    16861 tggctgctct actctattta ataaagaccc gtttgcatta cagaatggac agagtatttt
    16921 atggattttt tatttatttt taatgggtta tggtttgaaa gaatggaact ggaaagaaaa
    16981 ggtccgctat aagcttcctc aagtatttat cagcttgatt gttttattcg gtttgattat
    17041 tttgatgaca caaatttcac tcatcatcag aggaaataca gatacagcgc tgaggttttc
    17101 taaaccatat tctctcttcg caatgtatta tactttctct tcgtttttat ttttagaaat
    17161 gctatctgat aaattaggta taaaaggaag aggaaatttt cttgctgtat ttttgattgt
    17221 cactcaagtt atatgtaatt tccctttagt ttcttatcgc gtatctacat ttatgaaacg
    17281 tgaatttcca aactcaggga aggcatggct gataaatatc gggcagtttt ttatttgata
    17341 tttattagca gtgtccctcc tagttatctt tttattttat atacaaaaaa tccgtttcat
    17401 tcatcgtttc atcgaatact tcgcttttga ttcgattgaa caattaactc agcgttggaa
    17461 aaaaagaatt cattggcttt ttgttcataa aagttatttt ttagttgcag cattttttta
    17521 ctgctttacc ttcgtgcaga ttttcgtttt agaaccaaaa gaaggttgga aagaaactat
    17581 ccaggttgcc ttaaaaatat ttactcagcg acaagcaccc atgatcctga caatcatcat
    17641 tattatggga tttttcttct tactattgtt gatttccaat cgtttttggt acgccttgac
    17701 tgctaccttg atcattaact tactgctcac tatttcgaca gtaatcaaaa tggaaatgcg
    17761 ggaagagcct gtctttcctt cagatttaaa aatgctgacc ggattgtcag aactattatc
    17821 gatggttagc ccagtcttat taatcgtggg cggattgatc cttctcctat tattgattac
    17881 tagtattatt gtacaacgta gactacaaaa acagtattcc ttgaagattc attggaaacg
    17941 tcgatttatc agtatcgctg tattattagg atgtttttcg ggtgtctttt tcattaatca
    18001 caaaaattcg ccttctttct tgctgtttaa tttatttaaa gtaaacaaga ctttctttaa
    18061 ccagcaaggc gccgtaaaag ataacggacc agtcattcaa ttcctaaaca atatcgacat
    18121 taaaatcatg gaagaacctg ctggctattc gaaagaaaaa attaatggaa taatgaaaaa
    18181 gtacaacaca aaggcagatg aaatcaacca aacaagaagt gactggttaa acaatcagac
    18241 gatcgttctc aatttaagtg aaagcttcag tgatcctgca cgtgtcccta atctgacagt
    18301 acctacagac cctattcctt acatcaaaag cattataaca gaaggaacag gaggattgat
    18361 gttatccgtc ggttatggtg gcggaacagc taacatggaa tgggaaggac tgacaggctt
    18421 gagtatcagt aacctgtctg cttcgttagt tacaccttat acccagctag tggagcgtca
    18481 gaaaataagt ccaaatatta ccgatctatt cgatgaaaaa atagccatcc atccttttac
    18541 agctgctctt tatcgcagaa aacaagtgtt tgataaattt ggttttgaca ggttctatta
    18601 tttagacagt ccggataaat taacttatac ggataaaata gaacaaagcc cacgcatatc
    18661 ggatgattca gcatacaaag aaaccttgaa agctttacaa agcaatacgg aaacgtcaca
    18721 attcatccaa ttatccacta tgcaaaacca tatgccttat gatgattact atagtgaatt
    18781 gaactacact gctgaaggaa ctgctgtcat tcctaataga agaaaagaat tacaaactta
    18841 tatgcaaggc cttcactata ccgatacagc agtaaaaaaa ttcatccaag aaatcgacaa
    18901 aatcgataaa ccgattacct ttgtttttta tggtgaccat ttacccgcaa tctatagtgg
    18961 gaatgattcg aaaaaatatg gattagaaca gcaccagaca gattatttca tttataacaa
    19021 caagtatagt cgtgaacaag cagctacgtt aaataaagaa gttgttgctc ctaataactt
    19081 tggtgctatg gctcttgagc atgcgaatat caaagtaact ccttactatg cgttgttgac
    19141 agaagtatct aatcatctac ctgcattaac aattgatcct acagaaagct tgtctaatcg
    19201 ttttaatgga aaacaggtct ttgttacaga ggatagtcaa attatccaag aaaaaaattt
    19261 aactgagaaa caaaaagaaa ttctagaaga ttatcgtctg atacaatatg atcttgttgc
    19321 aggtaaccag tacagtgcaa catgggcgac acaaaaaata aaagactaac aaataaactg
    19381 agcaaggggt tgtgataaaa gacatgtcac aaccccttgt ttatctcatt aatttgcttg
    19441 tccataaacg atttgattaa agccattttt caattcatta ttcgctgtct cgttgaagta
    19501 aagataatta tcgggattcc cctgattttg ttgtgtcacc aatacttttg gctgattttg
    19561 ctgaaacccg aatagataga cgtgcttttt cagatatggt tctgtctctg catcggaata
    19621 gacggctgtg atttgatagt ctgcttgacc tgtcccactt tctgaccatt ctgcagaaac
    19681 aggcactcca ccaatagcca tcttccactc cccgttcaaa atagcttgag ggactttaag
    19741 accatataag tccacactca tttgattcgt ataacttttg tattgttgtc ccattgtttg
    19801 gccccatttg gtcataaatg cctctaattg tgcggatttg tctgcattcc acagtgtttg
    19861 ttcaacttgt tcgctgcttt ctgaagagga agatgaagcc tctacagaag aacttgaagt
    19921 agatgtttga gttgtttcag tcgttttgga agactctgac gaagtagagg tatctgctgt
    19981 ttctgtactt gctgcagttg acttgctctc tgtgctagtt gttgtagtag ttgcaactgt
    20041 tgctttcgct gtttcttttg ttgattcttt tttcgattca ttcccgttgg tacaaccagc
    20101 taacaaaaaa gctagaccaa ttgttactaa aatccttttt ttcaattaaa aaactccttt
    20161 cgattactcc cacttcttta ttctatcaaa taagcaatgt gattttattg atttttcgta
    20221 ttttctcatc aatctttcaa atcttctaaa aactgagaag cacccgctga tgttgtctgt
    20281 aatacatcag cgggtgcttc ttttatttta atcttcgtga ttttccaatt tacctcacgc
    20341 tttatatttg tatttgaaga aacatagact tttagtcatc atcgtcttcc tcatccaaat
    20401 cttgtcggac agtttttcct tggagtcttt gtacttggta gatgatttct ttattgaaac
    20461 ttaaaagttc aacaagcaat tgttgcaagc catatttttc ttctttttca gctaatttga
    20521 ttgcccgtgt gataaagaca ttttggaaat caaaatcttt tgcaaagttt tccaacattg
    20581 ttgaggctgg taaatatttg ttttgaccat gttcgtaaat ttttccataa cgcatgactt
    20641 cttctaaagt agacggaacg atttcatttt caatcactaa ctcatgagag attttattga
    20701 accatctcgc ttcttgatca gcatattctg aaaaaagggt acttaattct tgcgaagatg
    20761 tacccaaaac atacaattgt gcttggatca atttcatttc ttctaattta aaatttgcta
    20821 atacatgccc caccatggcg ccagcagttg gtttatgatg gtcgatatct gcttgttttg
    20881 tttcttgaac aaatttttct tccactatat tcattgattt acgcctcttt tacttttgct
    20941 gattggactt cataacctaa tttttccaca actgcagcta attgttcagg gtggacttca
    21001 tctggatcaa agtttgcttt gattttgctc gcattaaaca aaactttcgt attgcttacc
    21061 ccaggctgtt gagaaaccgc atgttcgatt ttttgcatac agcttggaca agctagtgta
    21121 tctaattgca taataatttt tttcatcgta gttcttcctt cctttttctt gatagtctta
    21181 ttctagatta cagcttccat aaaaaaattg attcttatca agttttacga tttttcttct
    21241 ttgctttcgt gtccaaaata caataaacgc atcgcgttaa agataacgat caagatacta
    21301 gcttcgtgaa cgaacatccc actagccatg taaataaacc cggcaaataa gccgttgagt
    21361 aaaaataaga cgacaccaat ggcaatcact acattttcac gggtatttaa aacagttttc
    21421 ttagccaagc ggtaggcatg aaccaacgat tcaaaattag attgcatcaa gacaacgtca
    21481 ctcgtttcga tagcaacatc cgttcctgat cccatagcaa tcccgatatc agccgcagcc
    21541 aaagagggag aatcattgat tccatctcca ataaaagcaa cgcgcaatcc ttgttcttgg
    21601 tattttttca caaattgaac cttttcgtct ggtaataatt cagcatggac ttcatcaatg
    21661 cctaacatat cagctacata atcagcagtc atctgattat cacctgtcag catcactaac
    21721 tgttttgctc ctgcttgttt caacttagct aattgttcag cgacttctgg tcgaatcaca
    21781 tctgacacac ctatgatttg agtgattttt ttgtcgattg ctacaataat gaccgagctg
    21841 cctgtttgtt gtaattgatg taaatcttgt acttgctttg gtgtgagaga aagtttgtga
    21901 gcggcaatca atttggtgtt gcccgcacaa actgtatgac catcaatctc agctgtgatt
    21961 ccttgtccct tgattgtctg attatctttg actgctaatt gttgaaaatc aatgtctttc
    22021 tcctgagcat aatggatcac ggcgcgcccc agaggatgat cggataacgt ttctaatcga
    22081 gccactaaag ctaagctgtc cccttcatcc tctgtatagt tcttgatagt ggatacagca
    22141 gtagttcctt tggtcaatgt accagtttta tcaaagacaa aagtatcgat tttggaaaaa
    22201 gtatccattg cttcaccgcc tttgactaag atgccccgtt tcgctccatt accgattcct
    22261 gctacattcg aaacaggcgc accaatgact aaagcgccag gacaaccaag aaccaaaaca
    22321 gtgattgcta aacgaaaatc acgactaatc agaccaacaa ccaacgcaat aagtaaaacg
    22381 gttggagtat aatactgaga aaatcgatca atgaattttt ccgcatggga tttggtatct
    22441 tgtgcttctt ctactaattc gataattttg gcaaaggtcg tatcatctcc gaccttagtt
    22501 gcttcaatcg tcacgtagcc atctgctaaa atcgttccag agaagacttc atctccactg
    22561 attttgacga cttgtcgtga ttcaccagtc actgcggctt catccgcata ccctttcccg
    22621 tcaatgactc gtccgtccac aggaatagct ccaccagttt ttactaagac gatatcgcct
    22681 tcttccacgt catcgatttc cacttcttca gtcgttccat cttcttggac aacactagca
    22741 gtagatgggg ccatctcggt caaagccttg attgactccc gcgttttggt caatgttttt
    22801 tgttccagat agctaccaaa caaaaacaag aatgtaacga tagctgactc cttgtattct
    22861 ccgatcataa aggcaccaag cacagcaata gtaacgagta aatcaattga gataactttg
    22921 actttcactg cctgatacgc atggatcata ataggtatga ccgcaataat agaagctatg
    22981 gctagagcaa tgttatagaa caagacaaaa ccagtaaatt ttccgataaa accaaaaata
    23041 atcaacacag ctgataaggc ggtgatatga tttcgatgct cttggatcca cttttgtaat
    23101 ttcatctttc tccctctttt cctttcattc ttacgagact aagtatagat acttatccat
    23161 cataaaaaat tgaccactat caagtttagt caaaaaggcg gttttctttt ggtagaatac
    23221 actacaaaaa atagttagca agaagactca ctaaaagtga tcttgccaac tattgtcgtt
    23281 tctatcgaaa ttttcattga atgattttcc tgtacagcat acatcggaga tctatttctt
    23341 tatctaagat ttttatcttg ctaatttttt cctttagtct ttcaaatcca cgtcgttcat
    23401 agaattgata cgtacagcca ctatctgtaa aaaggaatat ttcttttcct ttctctcttt
    23461 tttcaaattc tgttagcaac ttggtaccga tgccttttgt tttcaaatca ggatttgcag
    23521 ctaaaaaaat gatctctcca tctggcgaat gcttctttaa atatgctgca agcatttgtt
    23581 catttgctgt ctcgtaagct cctttacttt ctttagcaaa tatattttgt aaaaaatcga
    23641 atatcttaac atatatttgc tgtccaaaag aacgatgttt ctttttttct ccttttatct
    23701 ccgccagcaa aacacctgcc aactcgtcct ctgcatacaa agcaagaatt tgagttgctc
    23761 gattcaactc catatacaaa aaatatcttc cgtaaagatt cagcagaagt tcattttcca
    23821 tatatctctc aaagttcatt ccttcaacag caaaatagat agcttttttg taatctttct
    23881 tttctaaggg tttaaaagtt agtttcatca tttcgcctcc tcaacttcaa tgattgtgtt
    23941 atacttacat tataatagac acagtgtcta ctatctataa tcaatcatct ataagtttgt
    24001 cgattaagcg acagctttgc tttgatatgt cggataagga gataggtaaa tgaaaaagac
    24061 agatagacgc gtcaaaaaaa cagaaaaagc tttggctgaa acactatcca cattattagt
    24121 aaataaaaag attcaagcaa tcactatacg cgaactaaca gaaacggcag atgtacatcg
    24181 ttcgactttt tatacacatt ataaggatat ctatgatcta tatgatcaat tagaaagcaa
    24241 cttttttcgg gatctaaatg aaattctctc ttatgatcca gcccatagct atgaggaact
    24301 atacactcgc ttgattgact atgtttacgc aaatactttt ttatatcgct tatttatcct
    24361 caaccatggt gatatttcgt ttcagaagaa agttaaacaa gttattgaag aaaactatct
    24421 gaacatatgg ctatatgaag acaagaaaac gattatcaca gaagaaatga gattctttac
    24481 tacgtaccac gtccaaggtt gtctatccgt tctcaatcgg tgggtagaaa gcaattacaa
    24541 gtactccaaa aaagaattat tagaactctt acagaaactg aatgatcaca tagagaaaat
    24601 catgccttga ataaaaacat actaagctta gttaagaaga accgtaacct tctcgtataa
    24661 caactgaatc ttatttagcc aaattgttta ctgaagattt tttgagtaaa atttctataa
    24721 ttcctactta ttgaaaagta gtttgtagtg ctgcttctcc ctctctaagt gatatatctt
    24781 gttgtaccaa tcaaattcac ctcatcatta ataaattact tttaggctaa tttattacaa
    24841 cttataggtt gaagctgtaa ccaatttata gtcatattat atttttatca tccagtttat
    24901 tgaattcttc tcgtttacct caattcattt tcaaggggaa tcagctcatc atctaacatt
    24961 ttacgccatg ctcgcttcat ttcttgtggg tatttaaatg gtttcgcttc tggatgtttg
    25021 gctttatatc cttcgtaatc cttactgttg ataattgctt tcatattagg aattggatct
    25081 tcacctggca tatattgcag attagaagca tgtaattttt tctcagaaac aaaccactca
    25141 ttggaaaaga catgaatcaa atcatcactt acttgtgtaa aatagcgacg tttaatgaca
    25201 aagatatctt cattgctatc tagtgtacct tcatttcttt gtgcttaaat tcaaagataa
    25261 ttttctcaat aaagattttt gattccagta agattccttt actcctttta caacatagcg
    25321 ttgtcctttg ttttgaaaca tcttcttccc ctctttgcca ttaaaaatag cccaattctc
    25381 tataaagaag attaagcttc attattataa tataaagttt aaatttggtt tattacttac
    25441 tttttcttat tctctagtaa gctaatattg aaaaaaatgt aatcagatca ttatttttat
    25501 atgttgtaac ttcctgataa gaaaactaat taaaagaaag aggtaactac ataaactaat
    25561 taaaaaagct aacttcatag ttggaggata aatggaagaa acttcaatga ttgtttctcc
    25621 ttgtgttcct tcaatcgaca ctagtcctat tatcaatctc tcttttttgt ccatttactt
    25681 ttgcgactgt tccccaataa tcaaatacag gaagcgttat tttttgtcct ttagattcat
    25741 gtactgtata gactattttc gaatccatca cttgataagg catagtatgc cattccttgc
    25801 caattcttac ttcatgattc tgcaaatgtt ctttgtattg taatgcttcc gtgggtgcat
    25861 agtcataaag tcctccggga aggagtgtcg tgtaacgaat aagattttct tgattcatta
    25921 ccaagtgatc tctctgagtg acaactttat gttcatagtt tgcttttgtt gcagcagata
    25981 cagccaacag taataaaaca attgccgtta tattaactac ttttctttgc ttagctgatg
    26041 tgctcttcat gaaaacgaac gataaaatca acgagccaaa cagtacttga aagcctaaga
    26101 ttcgccaagg aaattgaatc atttgaatgg gtgtattttg taataaagac catggaaaaa
    26161 atttggtgga taagagccaa gagactaccg cactaaggta aatcactttt tctttgcgat
    26221 taaatccttt aaaaaagaag agtggacaga tcaaagaaat aataccaatg attcctaccg
    26281 taaaggttgt caggtcatta ttcatcgcac caatcaaact atccgagaca tttaatgctt
    26341 ggtgttgtaa ggtcgtttta tctggctcat taatcgattg aaccatgatt tgtcggaaca
    26401 tcggatacca aaagtatgct gttaaaagaa tcgtcattcc tactgccttt gacaactcca
    26461 caatcaaccg gatgctttct ttttttcttg tttcacttac tacaaagccg cctaagacta
    26521 gtaagccaac ggctattaca ctcataaaag tggaaagaac atgtgtataa atgagtaagc
    26581 tcatactgac tgctaatgga attgcacatg gctttttctc ataaatcagt gcgtaagcat
    26641 aatacataac tatcggtata accgtaagtg caatcgcttc agcaatagca gaacgatgat
    26701 aaatatcaat cgtacggtac ccataaaatg tatataaaca gctaaatata aaagccgcat
    26761 cgattctttt taaaaatttt agtccataat gaaacatcag catgatagta caaacattca
    26821 atagccaaac atataagata taactaacga ttaaattatt acttatccaa taaaaaatga
    26881 ctgccggaaa aaaggtcaag tagggataaa aataattcac tccgctccca taatgattaa
    26941 acgtcgtaaa attgattgga ccagaaaaaa ttgaagataa ccctttgact ctagcaaaat
    27001 ggaaggcaat atcccccgat gtagaaatag tatgaacatt tctaaaataa ttgattgaat
    27061 aaagtccagc aataattgct aggagaatgg acaatattat ttttttcttt acttgcatta
    27121 cttaattata tactcctttc atggattgct ttatctagta taacttaaat tttaaataaa
    27181 tcgttattta tttttactct cacttaaaaa agcactaaaa ttataagaga gggaggtaat
    27241 ggtctgaaca ccaagaattg ttccaacatc gaattgctta actaatgagt tcaaagctta
    27301 attatgtggc tcttatattt accgagcgtg gattgcgatc tctttagcga aacaaacatc
    27361 tttcataaaa aaaacagcca tatccgcttt cttggatatg actatttact actactttac
    27421 tatctttcat tcttcttgtc tcacttatga taaggcgccc ccgcattgat ccggaaggca
    27481 cggtagattt gctcgacaag gatcagacgc atcaattgat gtggatacgt catttttcca
    27541 aaagagatct gagcattgct tcttttcatg acggcttcgc tgagtcctaa agagccgccg
    27601 ataacaaaaa caaggtggct ttttccttgg atacctaatt ggtcgatttg tttagcaaaa
    27661 gattcacttg taggattttt cccttcaatt gctaaggcat agacgtattc ttgttctttg
    27721 attttcgcta agatccgttc cccttctttt tcttttactt gtctcatttg cgcttcgctt
    27781 aaattctccg gggctttttc gtcaggaact tcgatcaatt cgatttttgc ataggcattc
    27841 agccgtttga catactcatt gataccttgg atcaggtatt tttcttttaa ttttcctact
    27901 gagataattt tgatattcat gttttctctc ctttggtctt catgctcact ttgtttatta
    27961 taatcaattt tttcgtctat atgtttattt tggctatttt tgttaaaaag atttccccaa
    28021 cagttatgca caacatccac aggtttatcc acagaaaaca gtgttatttt accttatttc
    28081 atcacattca ttaggcaaac atacgtttta taagaattta tccactttat acacaggctg
    28141 tggatatgtt ttatccctta tttttccaat cctatccgcg tagttttaca cagtatctgt
    28201 ggaaaaagaa aatcaaatat tttcatctga aaacaatgat ttttcctaaa gtttttcata
    28261 aaaagttcac agtctcaaag tagactaaag tcaacaaata agactatact aacagtagat
    28321 aaatgaatgt aattggagga ggaacacatg gatagaaaaa atgtgacacc aaagatgaaa
    28381 aaaagtaaaa ataatagcct ctggcgtaag ttaggtctgg ggcttgttgg agggatcgtt
    28441 ggaggactac tgacagctgg cattttttat gcagcgatgg gcactggcaa caatagttct
    28501 actgctacaa gcggcaatca gaattctgcc ggtgaaacag ttgtggaaaa tgtcaaagtc
    28561 aatgtagatt ctgatatcac caaagcggta gataaagttc aagacgctgt cgtttctgtt
    28621 atcaacttac aaagtcaaaa ccaatcaagc ggttttggcg gactattcgg gcagcaagaa
    28681 gaaagtagca gctcagatga tagtaatttg gaagcttata gtgaaggaag cggcgtgatc
    28741 tacaaaaaag acgggaatac tgcttatgta gtcacgaata atcacgtagt agatggccag
    28801 caaggtcttg aagtcttgat gaaagacggt acgaaggtaa aagctgaatt agttggaaca
    28861 gatgcttatt cagatttagc ggtgttgaag atcaattcag acaaagtcga aacagttgcc
    28921 tcttttggtg actcaagtgc tctgaaggtt ggtgagcctg cgattgcgat tggttcccca
    28981 ctaggatctg aatatgcaaa ttctgtcact tcaggaatca tttcttcctt gaaccgacaa
    29041 gtgacaagta cgaatgaatc gaacgaaaca gtcaatatca atgcgatcca aacagatgca
    29101 gcaatcaacc ctggaaattc tggtggtcct ttagttaata tcgaaggaca agttatcggt
    29161 atcaactcaa gtaagatcgc aagtacttct gaatctactt ctaatgtaag cgtagaagga
    29221 atgggatttg ctattccaag taacgatgta gtgaatatca tcaatcaact ggaaaaagac
    29281 ggaaaagtga cacgtccagc tctaggtatc acaatggtcg acttatctgc cgtttctact
    29341 cagcaacaag aacaaatctt gaagattcct tcatctgtaa ctaacggtgt catcgtgaca
    29401 aatgtccaaa cagctacacc ggctgaaaaa gctggattga aacaatacga cgtcattact
    29461 aagatcgatg acaaagaagt ttcttctggt gtagaacttc aatctgcttt gtataagaaa
    29521 aaagtgggag attctgtcaa aatcacttac tatgaaggct cgaaagaaaa aacaactact
    29581 gttgaattga cgatcgatca atcggcatta aaacaaaatc aaaatagtga aaattaataa
    29641 aaaagaggtt gtgacaaaga cttgtcacaa cctctttatt ttggaaatgc ttctccgact
    29701 acggcatcct caggcaata
//
LOCUS       DBBGSZ010000033        29094 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.033, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000033 DBBGSZ010000000
VERSION     DBBGSZ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29094
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.033"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..1028)
                     /locus_tag="ACIZE5_001975"
     CDS             complement(<1..1028)
                     /locus_tag="ACIZE5_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6109095.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1110..1799)
                     /locus_tag="ACIZE5_001976"
     CDS             complement(1110..1799)
                     /locus_tag="ACIZE5_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HGC6109096.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1905..2273)
                     /gene="rplL"
                     /locus_tag="ACIZE5_001977"
     CDS             complement(1905..2273)
                     /gene="rplL"
                     /locus_tag="ACIZE5_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HGC6109097.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2326..2829)
                     /gene="rplJ"
                     /locus_tag="ACIZE5_001978"
     CDS             complement(2326..2829)
                     /gene="rplJ"
                     /locus_tag="ACIZE5_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HGC6109098.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3033..3160)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3239..3928)
                     /gene="rplA"
                     /locus_tag="ACIZE5_001979"
     CDS             complement(3239..3928)
                     /gene="rplA"
                     /locus_tag="ACIZE5_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HGC6109099.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4032..4454)
                     /gene="rplK"
                     /locus_tag="ACIZE5_001980"
     CDS             complement(4032..4454)
                     /gene="rplK"
                     /locus_tag="ACIZE5_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HGC6109100.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4797..5465
                     /gene="sdaAB"
                     /locus_tag="ACIZE5_001981"
     CDS             4797..5465
                     /gene="sdaAB"
                     /locus_tag="ACIZE5_001981"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HGC6109101.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5478..6350
                     /gene="sdaAA"
                     /locus_tag="ACIZE5_001982"
     CDS             5478..6350
                     /gene="sdaAA"
                     /locus_tag="ACIZE5_001982"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HGC6109102.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6441..7541)
                     /locus_tag="ACIZE5_001983"
                     /pseudo
     CDS             complement(6441..7541)
                     /locus_tag="ACIZE5_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324221.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            complement(7633..8520)
                     /locus_tag="ACIZE5_001984"
     CDS             complement(7633..8520)
                     /locus_tag="ACIZE5_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HGC6109103.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(8597..9142)
                     /gene="nusG"
                     /locus_tag="ACIZE5_001985"
     CDS             complement(8597..9142)
                     /gene="nusG"
                     /locus_tag="ACIZE5_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HGC6109104.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9243..9413)
                     /gene="secE"
                     /locus_tag="ACIZE5_001986"
     CDS             complement(9243..9413)
                     /gene="secE"
                     /locus_tag="ACIZE5_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HGC6109105.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9437..9589)
                     /gene="rpmG"
                     /locus_tag="ACIZE5_001987"
     CDS             complement(9437..9589)
                     /gene="rpmG"
                     /locus_tag="ACIZE5_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGC6109106.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9751..10395
                     /gene="cbpA"
                     /locus_tag="ACIZE5_001988"
     CDS             9751..10395
                     /gene="cbpA"
                     /locus_tag="ACIZE5_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-AMP binding protein CbpA"
                     /protein_id="HGC6109107.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10451..10954)
                     /locus_tag="ACIZE5_001989"
     CDS             complement(10451..10954)
                     /locus_tag="ACIZE5_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HGC6109108.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10967..11013)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11551..12516
                     /locus_tag="ACIZE5_001990"
     CDS             11551..12516
                     /locus_tag="ACIZE5_001990"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGC6109109.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12615..13787)
                     /locus_tag="ACIZE5_001991"
     CDS             complement(12615..13787)
                     /locus_tag="ACIZE5_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6109110.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13774..14919)
                     /locus_tag="ACIZE5_001992"
     CDS             complement(13774..14919)
                     /locus_tag="ACIZE5_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6109111.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14933..15865)
                     /locus_tag="ACIZE5_001993"
     CDS             complement(14933..15865)
                     /locus_tag="ACIZE5_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6109112.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15982..17061
                     /locus_tag="ACIZE5_001994"
     CDS             15982..17061
                     /locus_tag="ACIZE5_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HGC6109113.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17058..17676
                     /locus_tag="ACIZE5_001995"
                     /pseudo
     CDS             17058..17676
                     /locus_tag="ACIZE5_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
     gene            complement(17786..18013)
                     /locus_tag="ACIZE5_001996"
     CDS             complement(17786..18013)
                     /locus_tag="ACIZE5_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HGC6109114.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18116..20704)
                     /locus_tag="ACIZE5_001997"
     CDS             complement(18116..20704)
                     /locus_tag="ACIZE5_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HGC6109115.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20724..21383)
                     /locus_tag="ACIZE5_001998"
     CDS             complement(20724..21383)
                     /locus_tag="ACIZE5_001998"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGC6109116.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21432..21935)
                     /gene="trmL"
                     /locus_tag="ACIZE5_001999"
     CDS             complement(21432..21935)
                     /gene="trmL"
                     /locus_tag="ACIZE5_001999"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HGC6109117.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22156..23022)
                     /locus_tag="ACIZE5_002000"
     CDS             complement(22156..23022)
                     /locus_tag="ACIZE5_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HGC6109118.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23131..23772
                     /locus_tag="ACIZE5_002001"
     CDS             23131..23772
                     /locus_tag="ACIZE5_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HGC6109119.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23834..25195)
                     /gene="mgtE"
                     /locus_tag="ACIZE5_002002"
     CDS             complement(23834..25195)
                     /gene="mgtE"
                     /locus_tag="ACIZE5_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HGC6109120.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25213..26112)
                     /locus_tag="ACIZE5_002003"
     CDS             complement(25213..26112)
                     /locus_tag="ACIZE5_002003"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGC6109121.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26114..26911)
                     /locus_tag="ACIZE5_002004"
     CDS             complement(26114..26911)
                     /locus_tag="ACIZE5_002004"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HGC6109122.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26889..27593)
                     /locus_tag="ACIZE5_002005"
     CDS             complement(26889..27593)
                     /locus_tag="ACIZE5_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HGC6109123.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27724..28299
                     /locus_tag="ACIZE5_002006"
     CDS             27724..28299
                     /locus_tag="ACIZE5_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HGC6109124.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28417..29094
                     /locus_tag="ACIZE5_002007"
     CDS             28417..29094
                     /locus_tag="ACIZE5_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP adapter SpxH family protein"
                     /protein_id="HGC6109125.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8559 a         6167 c         5231 g         9137 t
ORIGIN      
        1 acagtattat ttcggttgct tgctgcttca cctagccctt gtactcgtgt ttgattggcg
       61 acttgaccaa attgattccc gacgtctaat aaaataatag ctaaaagcaa aatggccaaa
      121 tggcttccgc caaccaataa agcaataaag cttattgttt gcataacaag tcccatatac
      181 acgatttttc tttcagaata agaatctgcc agtcgtccca cgataggtgc agcaactgct
      241 ccagacaaac caaaaatcgc taatatccct gcttcgaatg ttccccaatt gtaggcggga
      301 ctgctgatat aaaaaatcaa cgtagaccaa aagatcgaaa atgttccaaa catgaaaaat
      361 ccactgactg ccgcttctct taatagacgt tgagaagcaa ctaaatgcgg caaactttta
      421 agtgaatcaa ggtatgaaac agctgtacta ctttgctgga cagaacgcgg cattttccag
      481 taaagcagaa gtgtaagaat tccgactgca cataaagcaa ataaatagat catccgccaa
      541 gaaaaaagac tggcaacaat accagatacc gtccgagaaa gcaaaatccc cacgagtaaa
      601 ccgctaagca atgtacccat gaccttccct cttgcttttg gtcccgctag taccgcaccg
      661 taaggaatga tgatttgcgg cacgatcgaa agtaatccta ttaaaaaaga agcgcatgca
      721 aataacgtaa acgaaggcgc aaaaaaagcg gccaacagag agacggcaga taacgctacc
      781 attcgaatga tcaattttgg acgatccacc acgtccccta aaggaactaa aaacagtaac
      841 cctaacgcat agcctaattg ggtcaacatc gtcaatatcc cgactgcact tgtgctaaca
      901 gataaactag ctgctacttt tgttccaatc ggctggatgt aatacatatt ggcaacaaca
      961 acgccacaag tgattgataa tagtaaaata agcgaagttg ttaaaggtgt tttttcatta
     1021 ctcttcattg atttccccca tttcctatct tagtttacaa cttatggaaa agattggaaa
     1081 tagaaaaata caactattcg ccacacttat tatttgtgct tttgttttcc ttgttttttc
     1141 ttgcgatctt tataaatgaa gacaactaac cctactagca cagtaacact tgcaaccaac
     1201 gtgactgcag ttttgttata tccgtgaaac agagcttctc caccacacgc atacaacaca
     1261 gacgaaggga tgactccaat cacgatcgac aatatgattt gctgtagagg caatttcatc
     1321 gcatctgcag caaaattgac catagaagat ggaataaccg gtatcatata gcctaacatt
     1381 acacctattt ttggatgttt catttgtcgg attgcttgca cccaatgatt cgtttcggtt
     1441 ttcttatcta aaaattttaa gcgatgcata aggaaaattg cagtgatgtt accaagagca
     1501 ttacccaaaa tgttgatgat cgcacctgtc agtggtccaa agctcaaacc agcaatgact
     1561 ccaactactg aagtaggaat acctggaaca gcacacatca ccgctgtcaa tacgatcaag
     1621 agtatcgatg caaaagtccc atgcgaacga atatgtgcga gtagctctgc cttactcgct
     1681 ctcggattta aaaataattg gatgtctgtc tgatattcta aatacaaccg atagcccact
     1741 accagtatca gaatgattcc caacgagatc aacatcaatc ggattatttt ctttttcata
     1801 tttcctcctg aaaaaaatct atattcatta aataatagtt taacataaaa acaaaaaagc
     1861 accgaaatcc aacataggat ctcagtgctt ttaaatagta aaaattattt aacagttaca
     1921 gatgcgccaa cttcttcaag tttagctttc aattcttcag cttcttcttt agatacgcct
     1981 tctttaactg gtgcaggagc gccatcaact acagctttag cttctttcaa gcctaaacca
     2041 gttgcttcac gaactgcttt gataacttta actttttggt ctccagctgc agttaattct
     2101 acagtgaatt ctgtttgttc ttcagcagca gcagcgccac cagcagcagc tacagctaca
     2161 ggagcagcag cagatacgcc aaattcttct tcaatagctt taactaggtc gttaagttct
     2221 aggatagttg cttcttttaa ctcagcaacg atgttttcaa tgttcaatgc cattataatt
     2281 tcctccgttt aattgttctt ttttatttaa tgctttatgc ggcaattaag ctgcatctcc
     2341 atcttctttg tctgccactg ctttgacagc gtaagccacg ttgcggactg gcgcttgtag
     2401 tacagatagc aacatagata gaagtccttc gcgatttggc aattttgcca atgctgtgat
     2461 ttcttccaat gaagagactt taccttcgat gataccgcct ttgatttcta atgcttttgc
     2521 ttctttagca aattcgtcca tgattttcgc tggtgcgact acatcttcgt tactgaatgc
     2581 aacagctgta ggtccagtga atacttcgtc catgccttca aggccagctt ttttagctgc
     2641 acgtgaaaga atagaatttt tgataacttt catttctacg ttagcatcac gaagttgttt
     2701 acgtaaacgt gttacttcat caactgttaa tccgcggtag tcaacgacta ctactgatgc
     2761 agctgctgta aatttttcgc ttacttcatc aacgattgct gctttttttg cgataattgc
     2821 ttcactcatt tttgagtttc acctcctgaa ttttgatgga agagtttttt gcactgaaaa
     2881 ggcaagtcac ttttatagtt actttgctca accagtatta ttcatcacct attcacttcg
     2941 ttcatagtga ttctactcgc tttgctcgaa aggaaactcc tttcgctttg ctcaaccagt
     3001 attgttcatc atctcttcac ttcgttcata gtgattcaca ataaaaaact ctatgccacc
     3061 gcagacatag agggactatt gaatatattc aataaacgtc ctcggtagga aattaaggct
     3121 tgatgccacc tactgtcttc ggtacaagtt aattattaac ctcaactagc ttagcatgct
     3181 aaactagttg agtcaagaat tatttttcag ttggatcaat caacattcta atatttaatt
     3241 agaaagaagc ttggtcaaca tggataccag gtccaaatgt tgttgtgatc gttacatttt
     3301 tcatgtattg acctttagct gctgatggtt tagcttttag caatacatca tggattgctg
     3361 caaagttttc aactaatttt tcatcgtcaa atgaaacttt tccgattggt acatggatat
     3421 ttccagcttt gtccacacgg taagttactt taccagcttt cacttcgttt actgcttttg
     3481 ttacgtccat tgtaactgta ccagttttag ggtttggcat taagcctttt ggtcctaata
     3541 ctcgtcctag acgacctaca gtagccatca tatcaggtgt tgcaacaact acatcaaagt
     3601 caaaccatcc gttttggatt ttttgaacca tgtcgtcgtc acctacgaaa tctgcaccag
     3661 ctgcttcagc ttcttttgct ttgtctcctt tagcaaaaac taaaacagtt tgtgttttac
     3721 cagttccgtt tggtaataca acagcaccac ggatttgttg gtctgctttt ttagggtcta
     3781 cgttcaaacg gtatgcaact tcaactgttg catcaaattt tgcaatgttt gtttcttttg
     3841 ctaaagctac tgcttcggca acaggataaa ctttacttga atcaactttt tttaatgcat
     3901 cttgcatttt tttgctcttt ttagccattt tggttcctcc ttgattgtgg ttataacggt
     3961 tgtacctccc acgtgttcta tatctttcaa tatagagcca actgagaagc tgctgtctta
     4021 gggtgtatag attattctac agtgatcccc atgcttcgtg cagttccttc aaccatgcgc
     4081 attgctgctt caacgttagc tgcgtttagg tcttccattt ttaattcagc gatttctctt
     4141 acttgatcgc tagaaacttt cgcaacttta tttttgtttg gttcgcctga acctttttcg
     4201 attttagctg cttttttcaa tagaacagca gctggcggtg tttttgtaac gaatgtgaat
     4261 gaacggtctt cgtatacaga aataacaacc ggaatgatca aacctgcttg atcagctgta
     4321 cgagcgttga attcttttgt gaatcccatg atattgatac ccgcttgacc tagtgcagga
     4381 cctactggtg gagctggagt tgctttacct gcaggaattt gcaatttaac gattttttct
     4441 actttctttg ccacgagaca tacctcctta agtccgtgat gtggttaatt ggagatgcat
     4501 atttctcctc ccacgtttta tctgatctga aaaaatccag acaaataatg tgcaaaacaa
     4561 tgcacactgg tacagtatag caaatttatt tgttttttca agattttttt ctgctatttt
     4621 tacattttgc ttgaataaac gctaaattta ttctaaaaaa acaacaattt ttcgttctca
     4681 tttcttcttt tatgttacac ttgcgctagc atggttcaac agatgaaagc aaacaataac
     4741 acggtttttt agacccttgt acaaagattc ctacataaca aaatgaggtg gagaaaatga
     4801 aagatttaag gtatagaagt gtctttgata ttattggacc tgtgatgatt ggtccaagta
     4861 gctctcacac tgccggagct gctagaatcg ggaaaatcat acgtagtata tttggcgaac
     4921 agcctgattc tgtagatatt tatctatatg aatcatttgc aaaaacctat cgggggcacg
     4981 gaacagatat tgcattagtt ggcggcctgt tagggatgga acccgatgat gaacgtttag
     5041 ctgattcttt gaaattggca tatgaagccg gtatggaagt cttgtttgtt cctaagagtg
     5101 aaaaagccga acatccaaac tctgtaaaga tgcttctaaa aaaaggaaca cgaaagcttt
     5161 cagtcactgg catttcgatc ggcggtggca atatccagat ttctgaattg aatggattca
     5221 aaatttcttt aagcatgggt actcctacct tgatcgttgt ccaccaagat gttccaggta
     5281 tgattgctaa agtgactagt atactttctg agaccaatac gaatatcggc actatgacag
     5341 tgacacggga atcaaaaggt gaaaatgcca ttatgataat tgaagtagat gatcctcaag
     5401 tagaagaaac ggtaaaaaga ctcaaacagc tgccaaatat cgacagcgta aattatttcg
     5461 attaaggagc taaaaaaatg tttttatcga ttgaagaatt agtagatcaa gcaaaagctt
     5521 atccaagtgt agcagaattg atgattgcag ttgaaatgga aatgagtggc cgttcccgta
     5581 gtcacatcat cgagatcatg gaaaaaaacc tctcagtaat ggaacaatca atcaacgagg
     5641 gaaaagaagg tgttacctcc gtcacaggaa ttaccggtgg tgatgcaaaa aaattagatg
     5701 attatttaaa tgaggcagac tttttaagtg gagaaacaat cttaaaagct gtacgcaatg
     5761 ctgtagctgt taatgaagtc aatgcaaaaa tggggttgat ttgtgctaca ccgactgccg
     5821 gaagcgcggg tgttgttcct ggtgtgctga tggctgtccg agatcggctt gatttgacac
     5881 atgaacagca attggaattc ttatttaccg ctggcgcttt cgggttagtc atcgcaaaca
     5941 acgcttctat cagtggtgca gaagggggat gtcaagcaga agttggttct gcaagtgcaa
     6001 tggcagcagc agctttggtt tgtgcaaaaa atgggactcc tcatcaagca gcacaagcag
     6061 tagccattac attgaaaaat atgatgggac tgatttgcga tcccgttgca ggcttagttg
     6121 aagtcccgtg tgtcaaacgt aatgctttag gctcttctca agcttttatc tctgctgata
     6181 tggcattagc gggtatcgaa agtgtcattc cgccggatga agtcgttgct gcaatgtacc
     6241 aagtcggacg tcaaatgccg tcgattttca aagaaacagc agaaggtggc ttagctgtta
     6301 cgccaactgc taaacgactt gcggaagaga ttttaaataa gagggcgtga taaagctcct
     6361 taatttcgag tattaagaga ttagttatct tcataacaaa aaacgaagag aggactaatt
     6421 gcccttctct tcgtttttta ttaatccatc aatttcgtat tttttacttc atcgatcgtt
     6481 tttgttcctg caagttgcat cgtgatcgac aattctttgt tcaggtgttc aaaaacagat
     6541 gttactcctt ctgccccacc tagattcaac ccataaatca ctggtcggcc aatcgcaact
     6601 aagtcagcac cacttgccag agctttgaag acatgctctc ctcgacggac accagagtcg
     6661 aaaatcactg gtacacgttt gttgactact tcggcaattt ttggcaatac ttcaaaggac
     6721 gcaggacctc catctaattg acgtccacca tgattggata cccagatacc atctgcccct
     6781 gcagagatag cgattactgc atcttctggc gattgtattc cttttacgat aactggaaga
     6841 tgggtgattt ctttgattgt tttgatgtca tctggtgtca agccttgttt tgcagctgca
     6901 taaatttctg cgattccttt tccttcgcca ttaccacttg cactttgttc gctatacgca
     6961 gctaagttag gcattggtaa tggaaattgg aattgattga tgacgtcttc ttcacggtaa
     7021 ccaccgagcg ttgaatctgc cgttaaaatg atagctttag cccctgcttc tactgctttg
     7081 ttcaaaatga actcattgaa tctgtcgtct ttactcatat ataattggaa aaactgcggt
     7141 gcgcctggcg ctgcatcggc tgcgtctttg attgtcgtat ttgcataagt gctgatggaa
     7201 aagattgatc cagcagcagc tactccttta gctgtatcag cttccccttt ttcatgtgcc
     7261 aatccttggg ccgctgatgg cgcttggata atcggtgtat ctaattcaat tccgaaaaca
     7321 gatgtatgca aatcggctga gtcgattccg cgtaatatcc gtggcatgat tttctttgta
     7381 ttaaaagaag tcgtattttc tttcatcgtc cactcatctt cagaaccacc gcgaatatag
     7441 ccaaaagctc ctgcttccat gcgctctttt acacgacctt ctagttaggc aatgtttaca
     7501 atatcgattg gatgttcttc attacttgta tgataagtca tagtagatcc ttctttcatc
     7561 ttcttgatta catataaatc atactaaact tacaaaaagt aagcaaacat ttactctcag
     7621 atacttttat cgctattctt tccaaataaa tcgacttaca agctgatcta cttcttggtt
     7681 ttcatgaagc atactatgag aggcattttc acctgtcact actttttcct ctatttcatt
     7741 tccgcgttgc ttcaacaacg catagaccgc taatgcactg tttaacggta ctgttccatc
     7801 actcaagtct gtttcatcta gttgaccagc aatcaagaaa aatcgagtgg ttataggaat
     7861 attaccgatc atttgctggt aatcttgata gcggttagaa acgacagcag gcccctttgc
     7921 taactcatct gtcagagact gcgcactatc atcgacaaaa tcattaaaag gcgcgccaat
     7981 tgctgttaat gtctgaactt gtggcaatga cgtatcctgt ccatacgttc ctaaatagcg
     8041 tagtgcacta actcctccca tggaatgccc cactatgttg actttatcta tgccgtagtt
     8101 ttctttcaga tacaaaagac aagttttgat ccattctgct tgattccact cgttattttt
     8161 attatcttca aacaatactt ggaccatcgg attgtctgct tttccagaca aatctcctgt
     8221 tgcttgtatt tgtccatctg ttcctactgt taaaaccaat tcttttactg cttgctgatt
     8281 tttttccaaa cgccgcaaca tccctttaaa ggaattttct gtcccgctgt agccgtggaa
     8341 aaaaagtgtt ggaatagtgg ttttttctat cactttactg gattctgccg ttttttcttt
     8401 atcagaaact tcagtagtat ttatcttcgt cgtctggcaa ccacttaacg caaacaaact
     8461 gataaggact aaagctgctg cagttgcacg tttgcataaa tttttgattg gttctgtcat
     8521 acacctcttc ctttccatat agaaaaaaga aagacttgaa aggccaatca tatgatcgac
     8581 atttcaagtc tctttattaa tcgattttat ctacttgatc gaaatcaagt tctgtactgg
     8641 tttcacgtcc aaacatatcg atgttgactt tcaatttttc tttttctccg tcaacttctg
     8701 ttacttgtcc ttctaatcca gcaaatgcgc cttcgatgat tttcacgact tcgccaactt
     8761 ctacttctag atcattttgt cgcaggctca taccgataga acgcaagata tgattgactt
     8821 cttctggaag taatggtgct ggtttgcttc cggctccgtg tgaaccaacg aatcctgtca
     8881 caccaggtgt gttgcggaca acataccatg aagcgtctgt catgatcatt tcaacaagta
     8941 cgtatcctgg gaatgtttta tgaacgattt ctttttcttt cccatttttg acttcagttt
     9001 ctttttcttc aggaacaacg acacggaaaa taaagtcggc cattttcata ctttgcgcac
     9061 gagattcgat atttgctttt actttgtttt catatcctga atatgtatgc aagacatacc
     9121 agtttttttc aaaagattcc attgaaggct cctcatttca ttgtaaaata aaaaaacctc
     9181 agtacacccg aagtttttct ttcgcttcat tatagcacta aaagtacgtt gtggctagcg
     9241 agttatttta aaatccagcc aaataagctt tggatggctg tatccattac gtaaaacatc
     9301 aatccgaaaa taatagaagt ttcgatgact actaacgtat ctttacggag ttgttttctg
     9361 cttggccaag ttacttgttt gatttcatct tttacgcttt ttagaaattt catgagacaa
     9421 cctcccttgc tactgtttat ttcgtttctt tatgtaatgt atattgatta caatatttac
     9481 aaaacttatt gatttccaaa cgttcgccgc tttttccttc actgactgat tttgtgtagt
     9541 tgcgagaccc acaaacggaa caagcgagtg ctgctttttt ctttgccatt tacttctgcc
     9601 cccttgctga gaatcagact tatacttcat aacagtatca cgtaactttt tacttgtcaa
     9661 tttgtgaaat aaactatcta ttgttttgga taaaattatg atatgattaa tttgaaatta
     9721 agctaaaatg agacaattgg aggtatagcg atgctattaa aaacacttgt atataagaaa
     9781 aaagatctga caaccgttac agagactagt acattagaag aagcattaaa aattttagaa
     9841 acttccggat accgttgtgt gccgatctta gattcttcag gtaatatttt ccgtggaaac
     9901 atttacaaaa tgcatatcta tcgtcataaa gcaaatggcg gtgatatgac gcttcctgtc
     9961 actcatcttt tgaaaaacgc tacaaagttc atttacctgg atacttcttt cttcaaagta
    10021 ttctttacga tcaaagagct tccttatatt gctgtccttg acagtgaaaa tcatttttat
    10081 ggtattttga cacatagtac gttgcttaat atgctctctc aatcttggag cgtagaacaa
    10141 ggaagctatg tactgacaat tgcttccaca ggaaagcaag gagatttggc tgctattgca
    10201 aaaatcattt caaaacacag cagcattgcc agctgtatta ctcttgatat cgaaaaagac
    10261 gaatacattc gacgtacatt gatcacgcta ccggctaaca ctgaagcgaa agtatgtgaa
    10321 acgatcgtca accacttaga gaaaaagaat tataaagtgg tagaaattga aaatttgcaa
    10381 aaccaagaag cataatcaaa aagcgaaaaa agaaaacagc taatctgctt tcttttttcg
    10441 ctttttataa ttagacacgc ttttcaaaat caagcgcgcg atctaaataa tacatcaatg
    10501 gtgctgaaac agccatgacg ataaactcac ttaatgcaag cgtgccatag gttgtccaaa
    10561 atgcttggcc acctgttgga actaacatat aagcaatcag tcccatgctg atggtaaaga
    10621 agatcgtgtt caatactaaa cgcatcttta catttttcac tttgttttgc aataaagctg
    10681 tcaggcctaa agaaagcaat gtttggccgc caccaaaaac cacatccatg ataccaaaac
    10741 caaagaaggc attatagacg atgaccccgc ctaaaactcc ccaaagcaat ttacggttaa
    10801 agacaactaa atgattcaaa ctttctgaaa tacgaaactg gatcggccct gaggatacag
    10861 gcgcaactaa aatagttaac gctagataaa gagccatgat gatgccattt acaacgatta
    10921 cggataaccg ttgtctgctt ttcgtttttt gcattttctc tcctcttttc tcctagtttt
    10981 tttaacgcgg gatggttgat gaaccgcggt tatgtgaaac aaacaataat tataacagac
    11041 ttttcattta tttcaatccg tcttatctgc ttttaaaaaa gcaaaagctt aaacaatgta
    11101 aacgtttgct aaaaatcgtg ggatatggta taaagtaagt gtaaggggtc ataagaattc
    11161 ccagtaaagc agacgaagta ggatctgcaa gaacagaatt gttgtgaaac ttaaataaat
    11221 aaaaaaggat gtgggaattt gagcaacctc ttactagaga acggtctagc aagcagctga
    11281 agatctaagt ggacatgccg aaccttggaa cttctcctta cgtaagtaat ggatcatgcg
    11341 cttgctaggc ttttttgtgt ttttcggtct tcggaccttt ttcattttcc tagacttctg
    11401 ctataataac caagaattaa ttttgtaaca gatttttttg aaaaaacaag tttctttcat
    11461 tcaaaaaata gaaaaagctt gctaattatt ggttaaccag caaacaggag tattaaaata
    11521 tcttgtttta ttgaatagca ggaggaaatc atgaaattcc attatcatat attgatcaat
    11581 ccatcggcag gcagcggaaa tggctataaa gtagcagaaa gaattttacc ggtattaaaa
    11641 aataagcata ttgactatac acttcattat agtgaataca aaggacacga tgctgagatt
    11701 gctgaaactt tggcaaaaga aacattgatt ccttggatag aagaagaaca gaaaacaatc
    11761 gatactttcc cccttttgat catcgtagga ggtgacggca ccttacatca ggtacttgat
    11821 actttctatc agatggaagt agaattccca gttgcttata ttccagcagg ttctggaaat
    11881 gattttgctc gaggggcagg ccttccaaaa aatcccaaaa aaggacttca gctgatttta
    11941 gcagctcaat caccagaaaa agtccacata atggcttatg aagaaaaaat aagtgaaaaa
    12001 aaaggaatag ctgttaataa tttcggtata ggattagatg cagctatcgt ccatgcgaca
    12061 aatcattctt ccacaaaaaa gcgattgaac aaatacaact taggatcatt ttcgtattta
    12121 ttctctattc tccgtgcttt attcactcaa aaaggatttc caattctggt agatgcagga
    12181 ggaaaacaat taagtttttc aaacgcattt ttatgtacag caacgaagca tccttttttt
    12241 ggcggaggaa tcgcgattgt tccaactgct gatgcgtcta aaccagtcat tgattttgtc
    12301 gtggtcgaac gaatcaattt ctttaaaatc ttgtggctca ttcttttact tatacagaaa
    12361 aaacaattga aatcgaaata tttccatcac tacacaacaa acagattacg tatcgtttca
    12421 acaacaccgc aacatggtca agaagatgga gaagaaatgg aaaaacgacc ttttgatatc
    12481 acaataacca caactaaaca gttgttttgg tgttaataaa agaggttttg tcagaagcta
    12541 catctggaac accgtttatt cggaaaaaag gactgtgaca cgacttttgt cacagtcctt
    12601 tttttactat gcagttaatt ctttgcccaa ttgggttgcc atcgatagtt tctttcttta
    12661 cccaaaataa attggatcat tgaaaacacc gcagcaaaag caactaagac acaaccattg
    12721 aaccaaaaag attctgcaaa tgtttgattg taactgagtg tttcactgat caagttatta
    12781 ttttgaacaa accaatatgt tggtgtgaat gccgctattt tgctaaccat ttctggcaag
    12841 tattctgctg gtacaaacac cccaccgata aagcaactgc ctgtgataaa aatatctttg
    12901 atcccaccgc tggtttctga gttttttacc aatgaagtga tacaagccga aaagctaatg
    12961 atcggcaata aaaacaagaa agtatttaaa atatgatacc ataccgttat atcccacgag
    13021 gtgtggatca ctaacagaac cattagaagt aagaagccac tgaacaacag cagcgagtaa
    13081 ctaatcaaac taaaggttac tttgcgattc aagtttcgtt tggtaatggg cgcactctgg
    13141 tttcgtttac tgatctcttt gcgattaaac gctagattga tgacgctgaa accgctaaaa
    13201 atggatagaa acaacccata agacaagaaa ttaaaggttg tgcccgtcaa cagctttttc
    13261 atccgctgac tatatcccgc acttagctca acttctccag taaccgagag tgccatttgt
    13321 gtctgttcca tagctgcatc gattgtttta tcttcttctt gaaacagaat cagtgtttgc
    13381 aaaaaggtgt tcacttgctg tgtaacaact gttttagaaa aggcatctgg gcgactctgt
    13441 atcttgatcg tcgccatctt tcctacttcg acttgttcgg taaagtctgc aggcagatgt
    13501 aagataatgt ttacacgatt aaaataaaga gcatcatcga tttctttttg tgaggttcca
    13561 tccaatgtaa cgactgtttc cttgtcattc aaatatttac gaaggccatc gactacaggc
    13621 gactcttctt cactaatcaa ggcgattttc gcatcttgca gagaggtatt ttcaacatca
    13681 atattttgcg caaaaaagaa tgtggcaaca acagtgataa ttacacctat cagtaaattc
    13741 gatttatttg ctttaagcaa tgtccaaatc gttttataaa gcgtcataac gcacccctct
    13801 ttccatccaa gcatttccta acgcaaaaag gaaaataaat ccgatcaacc atagaagatt
    13861 ggtataaaaa ctagccaaat cagtgtagaa ataaagttta tacaaacttt cgctgatcaa
    13921 gttgacgaga tttaattgac caacaatcgg aatatgaaga tcaatccaat acttcacttg
    13981 ttccgacccc atcataccag caaaaaagct catcgcaatc gtcactgaaa tcaagatgct
    14041 atccttttgc accagattca tttttggtat caaattacca accaatgtac ctaacaaaat
    14101 cgcacacaac gaccccagag cggtaacaat catcaaccat tgccaacgtt caccaaagtc
    14161 tacttgatag ataaaacgaa agacagctaa cataatataa atctctgtca aaacaatcgt
    14221 aaagcttgct gccaaattag cgattgaaac taacgattgc tttctaggaa tcaaggacaa
    14281 gcgaatacca tttgacgatt gatttgcttg ctgatcctgt acattgcgga ccccccacat
    14341 cgtcccgtag agaatcgcca ttccaatcag agtgaagaaa taaaaacttt tgaaactcat
    14401 attacgacct gcatgaactt cttgaaaaga tacttcttgt tcaaaaacag tcatgatggg
    14461 cgcgagatca acgttctcca cttctgccac tttactcgaa attataccaa tacgctgtaa
    14521 aaattgatcc atgacgtttt tcatcaacgt ctgactcatt cctgcttgac ccacatggag
    14581 cgaaacagat gaaccatcaa tgagataaaa accagccaaa tcatctgcat ttagcttttc
    14641 attcgcttct acttccgata gttcctgtac ttcaaataat ggtttatcat tgacttcgac
    14701 ttgttctaag actgtggtaa aattttccga aagcgctgtt tgatccgctt tgattacaat
    14761 tccagtatta atcgtttcaa gattgccacc ttgatcaatc tcgccaaagg ccgccataaa
    14821 catcaatcct aaaagaattg gaaaggccaa tgtccaaaac aacatggatt tatttcgcag
    14881 cagtattttt gtgcgatatt tataaaaatg ccaaaacatt atttcccctc ctctagtctc
    14941 tcaaatcctt gccagtaatc tctaaaaaga catcattcaa ggacgcttct ttggttgcta
    15001 tttttccgta actgatcttt tcttcttgta agattgtaag aatcggcaac aatactgtat
    15061 ttagttcagt agttgttact tggagctgac cttttttata agcgattcca tcagaagcta
    15121 ttgttcgctg aatcgctgac aacacatttt ctgggagtaa tgggatgtcg atcgtcaaac
    15181 gatccgccgt ccgtaccata tcttttagag attctttggt tcctttagca atcacctgtc
    15241 cttgatccat gatcacgatc tggtcgcaaa gaatttctac ttcttccatg taatgtgttg
    15301 tatagacaat ggttgctcct tgtcgattca gctccttgat actttctaaa attttattcc
    15361 gactttgggg gtctacagct actgtcggct catctaaaaa aattaaccgc ggcttgtggg
    15421 caatcccaca tgcgatgttc aaccgacgtt tcaagccacc actaagttct cctggacgaa
    15481 acgaaacata tttttctaat cccactaatt gaatcacctc ttcaatcaag gctttccttt
    15541 tctctttttc ggaaacatat aaaccgcaaa aataatcgat attttcttgc acacttagtt
    15601 cgtcaaagac cgcaacgtct tgaggaacga ccccaatcat tgccttgaca gcataatttt
    15661 caggagtcat tgttgtcccg aacaatttaa tggttccttt gtcataattt aacaaagaaa
    15721 gcatacagtt gatggcagtc gatttcccac tgccgtttgg acctaacaga cctaagactt
    15781 ctccttcttg tacttgcaga tcaaaatgat tcaatgctac aaaatctcca tagcgtttga
    15841 ctaatttatc aatttcgata atcatcatga aaaactcctt ccaaatttct tgttgatctg
    15901 actataataa agtgcaagaa aagaaactag tgacgattgg ctaaaccaca catgacattt
    15961 gtcacaatga aggagtctgc tatgcataaa tctcggctac tcaacgaaac tagctttcta
    16021 ctggttatct cattgctttt gctggtaagt caaggattcg ttgctatgca agttatctat
    16081 ttattgatcg ccgttttatt cactggtgtc agttatttac tgcctacaaa gccaaattgg
    16141 attttccaag ttattctatt tcttttatgt gcctttttac ctgatcttgt cctgtttctg
    16201 ccagcgacga tgcgagtgat cgcccctgaa gaaagccacc ttgattactt gtttttgtta
    16261 ggttttttgt tgatttcgac ggttggtaat catcccccca tcaaggtcgc ctttgtcgta
    16321 attttgctgt ttttttcctt ttacttacga aaaaaagatc aacgaacgac cgatcttgag
    16381 aaaaagtaca ttgtctccaa agatactcat tgggaaaaac aacaagagtt atcggaacaa
    16441 aataaagcat tggccctgtc acaagaaaca caattagcct tgcaaattgt ggaagaacgg
    16501 aaccgaattg cccgagacat ccatgacaat gtcggtcatc tgctgtcaag tgcgatttta
    16561 caaattggtg cgcttgaaat gatcaatcaa gaaccaaaac taaaagaacc attagaaaat
    16621 ttaagtgcca ccgttcacac tgggatggat cggattcgtc aaagtgtcca tgacctccat
    16681 gagacatcga tctcttttca acactcctta gagtttctga tcgctgattt tccttcttct
    16741 gttacgattg aaggaaactt gtttgaagga ttgaatgaaa cgcagcaaaa ctgcttctta
    16801 atggtcatca aagaagcctt aaccaacagt atcaaacata gtcatgccaa aaccgttgtt
    16861 ttacattttc gaacgttgcc ggccttttat cgcttgcaaa tcacgaatga tggcaccagc
    16921 ccacaaaaaa attctgctcc cggtattggt ttgaaaacga tgcgtcaacg tgttcaagaa
    16981 caaaagggac aagtccatat tttccaagaa aaccagcaat ttcagttaac gatcatttta
    17041 ccaagggagg gacaccaatg ataacagtag tcattattga tgatgatcca tttgtgacga
    17101 aatcgttaca aaccatttta gaaagcacga aagagatccg tgtgttaggc attggtcatt
    17161 gtgccaagga tgcgcgaaac ccatcgtccc gatgttttgc tgacggacat ccgcatgcct
    17221 aaacaaacgg gcatcgatgc tgccaaagaa attttggcta aatttcccaa agccatcctt
    17281 ttgcttttga cgacattcaa agatgaagaa tacatccgcg aagcattttc catcggtgtc
    17341 aaagggtatt taatcaaaca gaacttgcaa gcgattattc cttctgtcaa atccgcttat
    17401 aatggacagg ccgtatttgg taatgaaatc atcgagactt tcactcaaat gatgaagaat
    17461 aaaccgacga ttgatagtca tgcttatgct tcttttagtg aacgtgagct tgcaatcatc
    17521 aaagaagtag ctgccgggaa aaacaataaa gaaattgcag atgccttgta cttgagtgac
    17581 ggcactgttc gcaattacat cagccaatta ctagaaaagc tagatttacg ggatcgcacg
    17641 caattggcta tctattttta tcagcatttg caataagtct tatctaacac aaaaaaacct
    17701 gaatgatgct ccttcgcatc attcaggttt ttttcacatc ttctattcaa ttgtcccgca
    17761 aaccatttcc tcacgattga aagaatcaag gattcgcagg gctgccagga ttcgttggat
    17821 tgttcggcgt gttaggcgga aaaataggcg ccttgtctaa cgttttttct agttttgatt
    17881 cttcacgatc gtctcgttct acatcaggac tttcattcaa tttgaattct ttttccatct
    17941 catctaactt tttaaagtca ttgccagatt cttttgctaa tttcgctaat ttatcttcgg
    18001 tttctttagc cataaagtaa cgcccccctt ttgatttcag cttagcatat cacactgaaa
    18061 aaacaaaaga aaacgctaac caacgatcat ttttagctat ttctcatctt taaaatcaag
    18121 cattttttgc cggtataaaa tcgtagggag aactgttttc cataccaatc atcggatcta
    18181 ctaactggtt atcgatcact tctgctgtaa gaacgaaatc tttagaaaca gcaggttcta
    18241 cctcttcttt cttttcttct ccaacaaatg aagaaaacag atctggttcc actgtttcca
    18301 ttacttggtt tttcgtttca ttcgtcccac tgtcatcttc tacaggtagc ttttctttta
    18361 caacccgtgg ctcttttgta tagttcccat cttcaaatgg atcatttccg accaaagaat
    18421 cttcataagc tgctagtttg gtccggagag tgatattcat tttatcatta tccatgatcc
    18481 ttgatttcaa cgtagtcatc cggcttgctg attcattcgc tacacaagtg acataggctt
    18541 gctcttcccc taacaaaatc aacagttcct tactgcgagt cactgccgtg tagagcaaat
    18601 tacgctgaag catccgctga tattgatgga ccatgggcaa aataaccatc ttgaattcac
    18661 tgccttgtga tttatggatt gagcaacaat aagaaagagt gattttattc cattcgtttc
    18721 ttttataagt gacctcattt gcatcaaact ggataactaa ttcatccact ttatcttcag
    18781 aatcttttgc caagatgata cccgtgattt ctcccatatc tccattgaat acattcaatt
    18841 cgggagtatt gactaattgg aggactttgt ctcctatccg ataaacggtg tcgttccaat
    18901 gtacttcctt ttttccaggt ttccctggat tgaatatctc ctgcatcatt ttatttaacg
    18961 catcgatccc tgcaggtccc cgatacattg gtgctaatac ttggatatct tgtgcacgga
    19021 atcccttatt tttcgctttt tccacaattt tagagatcaa gggttcaatt tgataagcat
    19081 cacttcggaa ataggaacga tctttttgat tctttgtgaa atcttttggc agacgtcctt
    19141 ctttgatctc atgggcaaga ggaataatac tagaaccatc accttgccga taaatctgat
    19201 tgagttccat tttgggaatt tgttcgattt ccaaaagatc atggagtact tgaccaggac
    19261 cgacagaggg aagctgatct ttgtctccta ctaagataac ttgcatattc gtcggaatcg
    19321 ctttgaataa tgtgttagcc agccatgtat cgaccataga catctcatca acaatcaaaa
    19381 gtccgccttc taattctttc gtactgactg aaggtgtttt ttcccgtcca ttcagcccca
    19441 gaagacgatg gatcgtactg gcaggcagac ctgtcgtttc gttcattcgt ttagctgctc
    19501 ggccagttgg tgctgcaagt agaataggaa aaatttcttg ggtatatttt gaaggatcca
    19561 attccagtcc gttcaactct gcaaaaagat tgacgattcc gttgatcaca gtagttttcc
    19621 ccgtacctgg tcctcctgtt aaaataaata gaggggaacg gattgcttca gcgatagctt
    19681 gttcttgcga aggtccatac tgtatgccga atattttttc gatacgccga atattcttct
    19741 gcacttcttt ttcaggataa tggatttctt ttttacgact gagaaggcgc tggatcgaat
    19801 taccgatccc ccattcagaa aagtacaaac tgttttcgta aagattagtc tcttcttgtt
    19861 gtatctttcc ttcttcaaca agttggataa ttacagtagc aacctgatca ggctggattt
    19921 caattgggcg acttgtttct aaaatacgga tcgtttgctg aagcaatgtc tccgccggta
    19981 cgtatgtatc tcctgtttga actgcatgct gaaaaatctg atgcaagata gctgctcgaa
    20041 ttcttctcgg tgaatctgct gcaataccga tttgttcggc tagattatct gcacgtttga
    20101 acccgattcc ttctatgtct tcgactagct ggtacggatt ttcttcgatg atatccaaag
    20161 actcgttctt ataggcctgg tagatactga aagctaactg actaccgaac ccgtaacgat
    20221 tcagtcccat gatcacttga tccatcccgt ggtttagccg aatcgtctca gcaagcattt
    20281 ctctttttgg cttcgtcaaa ccggagattt gttttaatac cgaaggatca gcaatgattt
    20341 tttcgatagc atcttctccc agcaattcta caattttttc tgctgttttc ttcccgattc
    20401 ctgggaattt ttcgctggaa agatacgcta cgatcccatt tgcagttgtt ggcttttctt
    20461 gctcatatct ttcgagttta agctgccttc cgtatttagg atgatccact aattctccat
    20521 aaaaacgata agtctcattt tcttgaatat cgccgaaact tccggtgact acaatctctt
    20581 tttcacggta atcagctgtg gtttcactga tgtgtaccaa aagcactttg taaaaattac
    20641 taggattttg aaaaaaaatc gcggcaactg taccaacgaa ataaggcatt tcttctggct
    20701 gcatcggaag ccgcctcctt cttctatagt aaaggttctg gtgctgtttc agttcctaaa
    20761 aaatctgttt ggttccatac tttcagttca tatggcaata atctgcaagg ctcttcagtc
    20821 tctaaaatcg tcaaactact attgaacaat ccacccattt cacgcaactc acttagctct
    20881 tttcctgtca tccattgaat ggctgcagtt aaagaagctc catgtcctac gaataaaagt
    20941 gggccatctt tatgtcgggc aaccgcatct gctacaacag tttcgatacg tgtgattgcc
    21001 gattcaatcg tttctccgtg aaaaggagaa ggatcataca gatctaaatg attacgcaaa
    21061 ttcggcagat tatccggata tttctggtac atttcatcga tcgactgacc ttctaaagta
    21121 cccagcccta gttctcttag cttatctgta taaaaaatct ctaccggacg agcaagctct
    21181 ttgttgatac cttctgctgt atcacgtgct cgctttgctg tactggaata aattgcttta
    21241 aaaggaacat attttacctt tttcccaaat gctttgattt cttcgtaact ttgtggcaaa
    21301 agcggagaat cgccattgct cccttgaaaa cgtctttcct gattccattg tgtcttccca
    21361 tgtcgggtaa aatatagttc catacgcagc aaactcctgt ctttctttta ttttactcta
    21421 taataaactg tctaatccag cttgtcattt tcatagtgat gcgtcaattc taaattaggg
    21481 aatccttgct ggcgaagtgc ttcatacact atcattgcag ctgtattcga taaattcaat
    21541 gagcggacat gctcatcatt catagggatg cgtaaacact tttcttcgtt ttcacgcata
    21601 aatgtttctg gcaaaccggt tgtttctttt ccaaataaaa agaagtgctc ttctccatca
    21661 gcaaaatttt cgtcactata tactttatgg gcaaattttg agatcaaatg tagtttacga
    21721 ttacctaaaa atgttaaaaa agcttctaaa ttactgtggt aagtaatatt tacatcattc
    21781 caataatcca accctgcccg ttttagatgt ttgtcatcag ttgaaaaacc tagtggctcg
    21841 attaaatgaa gcggagtatt cgtggctgca cacgtacggg caatatttcc agtgtttgca
    21901 gggattaatg gttcaaataa aacgatatga ttcatcagga tcattcctct catatttatg
    21961 ttcgtttcta ttttctgaca atttgatttt tgcataaaaa aaaacgtatc aactcggtgt
    22021 cagtcactgc gagtcgttac gttagtgaag ctcttctcac taacttttat cagaacagga
    22081 acctgataaa aaccaatgaa aaaacaactt gttgctaata taacaccctc aacttttttt
    22141 tgcaacctct actcattaaa aactgctaga aaaacgtttt ctcttagttc cttttaataa
    22201 ttctatgtca attgtaatct tcttcaaagg attcttatat aagtctgctt tgattcgctc
    22261 ttctacctgc cattctaaag gtgacatggc caaaagatct ttttgatttt cctctggtat
    22321 ctcaaattca taggttacac gctgacgttc agttaatttc attgcttcag caaacttggc
    22381 tactacacgt tcattggaat aactctgttt ttcaggttga ttcggataaa aagcctgacg
    22441 tagttccttt aaataatttt cttgtggcac caccttcaac acttctccat cttctgagag
    22501 tacacgttgg aattcttggt aatgagaagg cgaaaagata tttaaaaccg cgttgaatgt
    22561 ttgatcagca aacggcaaat tggtcaaatc agctacacac caaaatgctt cggcagattg
    22621 ttctgtagct gcgtagactc cttcttttga aatatcaaat ccaacagcat tttgaatctt
    22681 tttcaatttt gaaagttcat tcaagaagct accttctccg cagccaacat ctaatagcga
    22741 gacttcttca ggtaaatgct gcgcaatagt ctcaataacg ggctgataca tgccagattg
    22801 gatcattcta cgccttggaa cgaacattcc ttgatcgtat tctgttttaa ccgcatggga
    22861 taaaaaataa agtgttcctt ttttggaaag gtcaaaacgg tgattatttt tgcatatcaa
    22921 gccattatca gactttttta cttcttcttg gcaaaccgga cagcggaaca gctgatgatt
    22981 ttctgccaaa aactggcgtc ctcggtcaat tttttttaac atagttcccc ctcatttctg
    23041 ttttatctta ccgttagatg ctcactttgg caactgctaa aaatatgata caatgcctag
    23101 aagaaagtga aagataaagg agaagattag atgatcaaag aattttgcgc tgaaaactac
    23161 acatctattc ctctagcaat tgctagagga gccgatcgga tcgaattgtg tgacaactta
    23221 gcggtcggtg gcacaacccc gagtactggt gtgatcgaag aaacgttaag ttatgctggg
    23281 gaaaaagata tccccgtaat gacgattatt cgtcctagag ggggcgactt cgtctataac
    23341 gatatcgaat tgaaaatcat gcatactgat ttgattgaag caaagaaatt agggacggat
    23401 ggcgtagtat ttggttgtct tactccttca ggctggctag acgaagaggc cttagaacta
    23461 ttgatcgaaa cagcagaagg gttgcagatc accttccata tggcttttga cagtattcct
    23521 gaagatcggc aattcgaagc aatcgattgg ctggtagaac atggtgttga ccgtatcttg
    23581 actcatggcg gtcctgctga caaaactatt gtagaaaatt tcccacggct taaagaattg
    23641 attgcctata cagatggccg cttaatcatt ttgcctggtg gtggtgtcac tgcagagaat
    23701 gcagcacatg tagctaaaga attgaacgta agcgaagtac acggaaccaa aatcgtggat
    23761 cttcagttat aatcttataa acaaaaaaac atttgcaaca ggcataatgc ttattgcaaa
    23821 tgtttttgtt tttttacata aaatagccca taaataaaga agcaatattg aaataaatca
    23881 gtacactcgt caaatcgctc aaagtcgtga taaagggacc gcttgctact gctggatcaa
    23941 atcctagacg atccattagc atcgggatta aactacctgc aagattcgcc actgtgattg
    24001 caaatagcat agccatccct atgacaaacc ccaagataaa attatgtttc caaaaaccta
    24061 cgattagaaa aatcgtgatc cccgtaacag ctcctgtgac aacgccggtc aagacttcag
    24121 ccaaaacaag tcgaacaaat ccatgatctt tctcatcaga aatcgcaagt cgacgaacag
    24181 ccacagctag cgactgggtt ccagcattac cggcagttcc tgtaatcagc gaaatgaaga
    24241 ctgctaaaat actcgcttca cttaccaagt cttcatagtg actgattaaa gaagcggtcg
    24301 acatacctaa aaacaacaga gtgatcagcc aaggcaaacg tcgagacgct gcctttactg
    24361 gattttcatt aatttcttcc acattgaccc cggcaagtcc tgaataatcg ctagcagctt
    24421 catcatcaat aacgtcgatg atatcatcga ctgtgacgat tcctaacaaa tgatcatcat
    24481 aatcggtaac aggaagagct aagaagtcat aatctctaaa tgtttgtgcc acatcttctt
    24541 ggtcgtcgcc tacatgaact gaaagcactc gttcgctcat cagatcagaa atcattgcgt
    24601 cgtcatcatt cacgattagg tcgcgcagag aaataacccc tactagctga ccttcttgat
    24661 taacgacata gatgtaatag attgtttcag ctacatctgc ttcgttcttc agcacgtaca
    24721 tcgcagagcg aacagtttga ttggctacga tcgaaacaaa ttcagttgtc atgatcgcgc
    24781 cagccgtttc atcctcgtaa tggagaagtt ccttgatttc actggcatcg tctgccgaca
    24841 tcaaacttaa atatttagca atttgctttt tatccagcgt attaagcaag tcaacagcat
    24901 tatctgtata catctcagaa agcatatcag ctgcatagct aggacgcatt tcatctaggt
    24961 attctttcat atgttcgttg tcttcttcaa tcacatcgaa catatccgct aattctttag
    25021 gcgacagata ggaatagatc agctgcctgt tctcttctgt aagagattgg tagaattgcc
    25081 cctgctcata gatatgcatc tctaaaaaac tgtttctgaa tgcctgaata ttattttccc
    25141 ttaaatcttg agtcaactgg gcaaatcttt cctctaattc ttgattttca tccaaaccaa
    25201 tctcacctcg ccttattctt caaaccgtct cacaactgcc tccatgtctg cggctaaagg
    25261 ctgcttgaac tccagcaact cttctgtaaa tggatggtaa aaacgcagat cataacaatg
    25321 aagggcttgt ctttttattc ccagatccat tcgcccgcca tacatatcat caccgagcag
    25381 ggcacagcca attgcggaaa aatgaactct tatttgatgt gtccttcctg tatgcagctg
    25441 gatatcaact aacgcgattt ctgttagtcg cttctctatc cagtactcag tctgtgccga
    25501 acgtccttca tcagagacca ttcgcttcaa tagcgaagaa taatctcggg cgatcggcaa
    25561 atcgatatgt ccatgtgccg ataaatctga aagccttcca ctgactaagg cctgatattt
    25621 tttcacaaac ttcttttcac gaagttgcat atctaatttt gcgtgcgcaa atccatgctt
    25681 tgcaaaaagc atcaagccag atgtatcccg atctagtcgc gtcaccacat ggattacttg
    25741 gttttcgtaa ccttgttttt tataataagc ctttacacga ttagccattg tcccatttgg
    25801 atggtattgg gcaggaatag acgaaacgcc tgctggttta tttactacca gaacgtgttc
    25861 atcttcatac acgatatcga tcggtgtttc atccaaaagt acggtttcat gttctccttc
    25921 agcaggaatc acaatggtta ccttatcatc cttagctaga gaaaacaaga cattttctac
    25981 ttgatcatta actttgattt gaccgccttg aaattttatt ttcgctaaca gaccctttga
    26041 gatccctttt tcttttaaaa aatattttac ttgctgagaa tgatctttct cataatccca
    26101 tgtaaactgc atatcaatcc tcactaataa aggcatcttt cacacgatgc caaaaatgca
    26161 tatgtcgata agaagcaaaa tggatccgtt cttctgctat tcgataataa attgagcgga
    26221 tatttgcttt tgcgacattc aattgatcaa ccgttacaag ataatcttct gtattttcca
    26281 attttatttc tagccattca tcatgggcaa tcacgatcgg agaacccaaa gtacgaaaca
    26341 ctcgattatt cagtgaagca atctctgcca actgaaaggc attgatacta ggatggatca
    26401 cagcaccgcc gacactttta ttatatgctg tcgaaccagt aggcgtagaa atcgtcaatc
    26461 catctcctct aaaactttca aacagctcgt ttttgatgta tacatcggct accatcgtac
    26521 gattggcccg tttaatcgtt gattcattca gtgctaaaaa atgctggtcc ggtgtttcat
    26581 ccaaataact gatccgaaca tccagcaagg gataactaac actttgttcc cggttcgttc
    26641 gtaagctgtc tactagttct tccagctcgt aatcccgcca atccgtgtaa aaccctaaat
    26701 gacctgtatg cacgcccaag aaacgcacat cattcagaca atgactgtag tgatggaacg
    26761 ccgacaataa tgtgccgtct ccgccgactg agatgaccaa ttctggctca tgatcatctc
    26821 gttgaatccc tgcttgttct aaaagtgcgt tcaaacgttc tgtcacttct atagtctttg
    26881 cttctttatt atgaacgatc gctactttca tcccctgcct cctctctttc gctttctttc
    26941 ttcaaaagcg ttcgatagta gacatcatct gattttcctc ttccatggga gaataaccgc
    27001 tgtgcttctt ggatttcttc acggatactg gacatctctt catccaactg ataggcagct
    27061 tctgccgcac gctgaagtcg ttcactcatt tcttctggaa aaacgccttg atatttataa
    27121 ttcagcgaat gctcaatcgt tgcccagaaa ttcatcgcaa gagtccgaat ctggatttcc
    27181 gccaaaattt tcttctcacc gctgatcagc tgtacaggat actcgatcac cagatgataa
    27241 gaacggtagc cacttgcttt tttatttgtg atgtaatctc gttcttggag aactttcatg
    27301 tcttttcttt tacggatgat ctcaacaact tgatggatat cttctacaaa ctgacacatg
    27361 atccttaacc cggcaatatc agacatttct tcttctaaac gtcccattgg aatatgccgt
    27421 aattgtgatt ttgttacaat actatcgact ggcttgactc tcccagtgac aaattcaatc
    27481 gggacatgtc gattttgttc acggaactgt ttgcggatcc cccgcagttt cactttcaat
    27541 tctgatacag tttgttcata tggtgctaaa aatgcttccc aatctcgttc catagctgat
    27601 acctctactt cattaacatt cattgtttat tctaccatat atgcaaagtt ttttcgtact
    27661 cttgatttat gcattgacca aaaaaagaaa attaggcaaa atagacaaaa aggagtcgat
    27721 caaatgacac aaatgcttga aatcgaatat aaatctatgc tgacaaagca agagtacgag
    27781 atattcatcg ctcactatca attaacagat aaagatttcc gtgtacagac taatatttat
    27841 ttcgataccg ttgatgaaca gctgaagaaa caaaattgtg gcctacggat ccgtttcgtt
    27901 ggtcatcaag ctgaatatac attaaaaaca cctgctgaaa aagggcgtct cgaaacaacg
    27961 gataccttta taacagaaga agcagaagca tttatcttcg aaaaacgtct gcctcgttca
    28021 ggcgcagttt ttcaaaaact ttctgatttg aatatcgatc ctgcttcatt aatccaaacc
    28081 ggaaagctta caacaaaacg agctgaattc cctattgaag aaggactttt agctattgat
    28141 gaaagctggg gagacaatct acacgatttt gaactggaac tagaggtagg ggatgcatct
    28201 gtgggaaaaa ttgcttttat aaatttttta aaacgttttt ctttacctta tcgtcctgct
    28261 aagaacaaga tccaacgtat gcttgaagct aaaaattaga aacctttcat tttcacaagg
    28321 cacttgagtt cattttttta cttttttctg ttaagttata ggatgtgaaa gaatctagtc
    28381 actagttgta tagaatctat tttgggggag attcatatga tcgaaatcta tttatttgtt
    28441 aatcctttag gggaatactg tttcgaaatg gaacaacagt tattacaatt tatcgaagaa
    28501 gagtacggga caccatcaaa agaaaagatg caatttcgct ttcttccttt ggtcaatttg
    28561 cagacaattg gggatgtcat gcaacaaaaa ggaatttctc agaacaatct tgaggaacgt
    28621 aatcacttat tctcaatgac ttattctgca gcattggact gcaaagcggc gcagtttcaa
    28681 ggaaagaaaa aaggccgccg ttttttgatc aaattgcaag aagcagtcgg ctgtaatgac
    28741 ataccatatt ctcaagaact tgctgaatcc atatttgaag aaatcggcgg cgatttgaat
    28801 atgtttaaag aagatcgtca gtctgacttc gttaaagaag tattcttttc tgatcaaaaa
    28861 attgctcggg aaatgggcat cacaaaacac ccttctgcag tcgtttacaa ttatgcctgc
    28921 gaccgtgatt ttggtgtttt agtagaagta aaaggtacaa gtagcctttg gagaatcaca
    28981 gagctgtgta aaacaacaga taactcatat caagttttta atggtgaaca tttacataca
    29041 aatgattctc agttccattc aagaactagc catttacact tgctttctaa ttaa
//
LOCUS       DBBGSZ010000034        28330 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.034, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000034 DBBGSZ010000000
VERSION     DBBGSZ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 28330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28330
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.034"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(171..359)
                     /gene="rpmB"
                     /locus_tag="ACIZE5_002008"
     CDS             complement(171..359)
                     /gene="rpmB"
                     /locus_tag="ACIZE5_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HGC6109126.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            629..991
                     /locus_tag="ACIZE5_002009"
     CDS             629..991
                     /locus_tag="ACIZE5_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGC6109127.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            1043..2725
                     /locus_tag="ACIZE5_002010"
     CDS             1043..2725
                     /locus_tag="ACIZE5_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HGC6109128.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2842..4878
                     /gene="recG"
                     /locus_tag="ACIZE5_002011"
     CDS             2842..4878
                     /gene="recG"
                     /locus_tag="ACIZE5_002011"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HGC6109129.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4927..5928
                     /gene="plsX"
                     /locus_tag="ACIZE5_002012"
     CDS             4927..5928
                     /gene="plsX"
                     /locus_tag="ACIZE5_002012"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HGC6109130.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            6050..6292
                     /gene="acpP"
                     /locus_tag="ACIZE5_002013"
     CDS             6050..6292
                     /gene="acpP"
                     /locus_tag="ACIZE5_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGC6109131.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            6560..7564
                     /locus_tag="ACIZE5_002014"
     CDS             6560..7564
                     /locus_tag="ACIZE5_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6109132.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            7565..8509
                     /locus_tag="ACIZE5_002015"
     CDS             7565..8509
                     /locus_tag="ACIZE5_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6109133.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            8509..9471
                     /gene="opp4B"
                     /locus_tag="ACIZE5_002016"
     CDS             8509..9471
                     /gene="opp4B"
                     /locus_tag="ACIZE5_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HGC6109134.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            9498..10412
                     /locus_tag="ACIZE5_002017"
     CDS             9498..10412
                     /locus_tag="ACIZE5_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6109135.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            10438..12219
                     /locus_tag="ACIZE5_002018"
     CDS             10438..12219
                     /locus_tag="ACIZE5_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC6109136.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            12567..13253
                     /gene="rnc"
                     /locus_tag="ACIZE5_002019"
     CDS             12567..13253
                     /gene="rnc"
                     /locus_tag="ACIZE5_002019"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HGC6109137.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            13273..16854
                     /gene="smc"
                     /locus_tag="ACIZE5_002020"
     CDS             13273..16854
                     /gene="smc"
                     /locus_tag="ACIZE5_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HGC6109138.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            16863..17672
                     /locus_tag="ACIZE5_002021"
     CDS             16863..17672
                     /locus_tag="ACIZE5_002021"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC6109139.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            17683..18681
                     /gene="ftsY"
                     /locus_tag="ACIZE5_002022"
     CDS             17683..18681
                     /gene="ftsY"
                     /locus_tag="ACIZE5_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HGC6109140.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            18868..21135
                     /gene="gshAB"
                     /locus_tag="ACIZE5_002023"
     CDS             18868..21135
                     /gene="gshAB"
                     /locus_tag="ACIZE5_002023"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HGC6109141.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(21224..21676)
                     /locus_tag="ACIZE5_002024"
     CDS             complement(21224..21676)
                     /locus_tag="ACIZE5_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HGC6109142.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            21826..22776
                     /locus_tag="ACIZE5_002025"
     CDS             21826..22776
                     /locus_tag="ACIZE5_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGC6109143.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            22769..23728
                     /locus_tag="ACIZE5_002026"
     CDS             22769..23728
                     /locus_tag="ACIZE5_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGC6109144.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            23725..24480
                     /locus_tag="ACIZE5_002027"
     CDS             23725..24480
                     /locus_tag="ACIZE5_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6109145.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHIGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            24503..25456
                     /locus_tag="ACIZE5_002028"
     CDS             24503..25456
                     /locus_tag="ACIZE5_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC6109146.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(26100..26396)
                     /locus_tag="ACIZE5_002029"
     CDS             complement(26100..26396)
                     /locus_tag="ACIZE5_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HGC6109147.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            26751..27107
                     /locus_tag="ACIZE5_002030"
     CDS             26751..27107
                     /locus_tag="ACIZE5_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HGC6109148.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            27117..28016
                     /locus_tag="ACIZE5_002031"
     CDS             27117..28016
                     /locus_tag="ACIZE5_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGC6109149.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
BASE COUNT         9405 a         4972 c         6111 g         7842 t
ORIGIN      
        1 aaaagagtct agttttcaca aaaaaataaa atttagaata aataacttca taatttgttc
       61 gtataacaaa aataaacgca aaaaaagggt aggaatcaaa agtcccaccc ttaaaaattt
      121 ttattaaata aaaaaccgtt cactatctga acggtccaag tatcattcaa ttaaacgcgt
      181 tcaacttttc ctgatttcaa agcacgagtt gacacccaaa cttttttagg ttttccgtcg
      241 accataacgc gaactttttg taagttaggt ttaacagtac gttttgttga gttcatagcg
      301 tgtgaacggt tgtttccact ttttgtcttg cgacctgtaa agtaacaaac ttttgccatg
      361 gtaatttcct cctttgcctt gatttggagc aatagaataa ttcagctcat accagactaa
      421 catatcatat agaatgggaa tttgcaagta cattttcata gatacaattg acaattgaga
      481 agaataattg taaattaaac aaggttatac ctgaaatttt gcaaggtttt tgagtacttt
      541 gggtaactgc cttttatttc aagttgcgct atgataaaat atgatagaag aaaaatggga
      601 gttttttacc cgttaaggag gctcattcat ggctgtaaaa attcaaacgt cagctggaac
      661 cattgaaatt accaatgatg taattgcaac agttgttggt ggcgccgcga cagatgtgtt
      721 cggtgttgta ggaatggcca gcaaaaatca aattaaagat aatattactg agattttgcg
      781 taaagaaaat tactcaagag gagtagttgt ccgccaagaa gataatggta ttgctgtaga
      841 tgtttatacg attatcagct atggtacgaa aatctctgaa gtttcccgca acgtccaaga
      901 aaaagtgaaa tacaatctag aggcattatt aggcgtaact gccaattcag ttaatgtctt
      961 tgtacaaggt gttcgtgtac tgccagacta ggcaggagac tggctggtaa ctcagcagtc
     1021 gatctgaagg aggattatct aggtgagtgt aacagaaata agtgcaagcc agttccagga
     1081 aatggtccag gcaggtgcga atcgtctgca agtaaatgca gaatacgtca attcattaaa
     1141 tgtattccct gtgccagatg gcgatacggg aacaaatatg aatctatcta tgactagtgg
     1201 agctaaggca gtagtagatt caacctcaga aaaagtagga gaattagcag caatgctttc
     1261 aaaaggattg ctgatgggtg cgcgcggaaa ttccggcgtt attttgtctc aattgtttcg
     1321 tggattttct aagcaaattc cagatgttgt ctcattaaat gcttctgatc ttgctgcagc
     1381 cttcactcat ggagttgaaa ctgcgtataa agcagtaatg aaaccagtag aaggaacgat
     1441 tttgacagta gctagagaag cagcgaaagc tggagaaaag aaagcaaaaa gtactgatga
     1501 tgtcgttgaa gtaatgacag ctgttgtaaa aggagcaaag cgtgctttag ctaaaactcc
     1561 agacttgctt ccagtcctaa aagaagtcgg tgtcgtagac agtggagggc aaggactgct
     1621 gtttgtttat gagggctttt taagtgcatt gaatggagaa ttccaagcgg atgaaacata
     1681 tgaaccttct ccagcagaaa tggatgatat ggtcaatgca gaacatcatc gcagtgtcca
     1741 aggtcaaatg gcgacagaag atatccattt tggttactgt acagaaatca tggtaaaaat
     1801 cggagaagga cctacagtcg atagtacatt cgattacgaa gaattccgta actatttaga
     1861 tggtatagga gattctttac ttgtggtcaa tgatgacgag atcatcaaag tccacgtgca
     1921 tacagaaaac ccaggagaag tcttgaatta tggacaaaaa ttcggttcat tagtcaaaat
     1981 caaagtcgac aacatgcgct tgcagcatga gacgattttg gaacacgatg aagaagtgaa
     2041 cgagtttgcg aaaaaagaaa taccacgtat cccgtatggt atcgtagcga tcgctgctgg
     2101 taaaggcgtc caagagctgt ttgaaagttt aggcgctaat tatgttatca gtggtggaca
     2161 aacaatgaat ccaagtacgg aagacattgt taaagcgatt caagaagtaa acgcagataa
     2221 agtgattgtc ttgccaaaca ataagaacat cttcatggca gctgatcaag cagcagaagt
     2281 agcagatatc ccagtagcag ttgttccttc aagaacgatt tcccaaggat tgacagctat
     2341 gctttcattc aatgatcaag cttctttaga agaaaacaaa gaaacgatga cagaaatgtt
     2401 gtctagcgtt gtgagcggtc aagtcactca cgcgatcaga gatacctcaa ttgacggtgt
     2461 agagatcaaa gaaggagact ttttgggcat gatcgatgga aaaatcctga tctctaaccc
     2521 agatatcaca gcaacagcgt taagtacact agaacaaatg atcaatgagg acacagagat
     2581 cgtaacgatc ttggcaggtg atgaaggaac agttgaacaa gcaaatgaat ttgctgagaa
     2641 actaacagaa aaacatcctg atttggaaat cgagatccac caaggagatc agcctgtcta
     2701 tccttatcta ttttctgctg aataatttct gtgtcagaat atctttctaa cacagtattc
     2761 attcataaaa ggccttcggt tagtgatcag gtatgatcgc tgaccaagtc ctttttttgt
     2821 taaaggaggg aggaaaaatt tatgcgttct ttagatgatc caatcactat gctggcagga
     2881 gtcggagaaa aaagagcagc tagtcttgcc agcttgggca tccaaacgat tgaagactta
     2941 ctgacttatt atccttttcg ctacgaagat attcaggaaa gaaatctaaa cgagatccag
     3001 gatcaagaaa aggttacttt gaaaggaatc gtagtctcgc ctcctgtgat gaatcgattt
     3061 ggttataaaa aaagccgatt gcaatttcgt atgatgcaag aacatgatgt gttcaacgtt
     3121 tcttttttta atcaacctta tctaaaagaa aaagtcattt tatcggagga aatcgccgta
     3181 tacggtaaat gggatgcaaa gcgtaaagcc ttgaacggga tgaagatttt aggttctcaa
     3241 acaatggatg acttttcgcc gatatatcac gtcaacaaat caattcgtca aacgacatta
     3301 gttgatctaa tcaaaaaagg gtttcaagaa tacggcacat tgattgaaga aaatctgcca
     3361 aacaaccttg tggagaaata tcgactgctt gaccgagctt ctgctgtaag aagtatgcat
     3421 tttccaaaag accacgaaga aaaccatcaa gccaaacgac gtgtcgtttt tgaagagttc
     3481 tttttatttc aaatgcgtct tcaaggattg aaaaaagcag aaaaagcaga aacgaatggt
     3541 ttggagatcc tttatgatgt ccaaaaattg aaacaattta ctcaaaagct accttttgaa
     3601 ctgacaaatg cacaaaaacg tgtaacgaat gaaatctgtc gggatcttcg cagtccgcag
     3661 catatgcagc gacttttgca gggagatgta ggtagcggaa aaacagtggt tgccgcgatt
     3721 gcgttatacg ctaccgttac agcaggtttc caaggtgcgt tgatggtgcc tacagaaatc
     3781 ttggcacaac aacatatgga aagcttgcaa cagctgtttg atcccaatga agtaaccatc
     3841 gcattgatta cggggtcaac gaaagcaaaa gaacgacgtg agctccttga aaaactagag
     3901 caaggggaaa ttaacgtcgt gatcggcaca catgcattga tccaagatgg agtcgaattt
     3961 cagaatttag gtctagttat tacggatgag cagcaccgtt ttggcgtgaa ccagcggaaa
     4021 gtacttcgtg aaaaaggctg gcgaccagat gtcttattta tgacagcgac tccgattcct
     4081 agaacattag ctattacagc atatggtgag atggatgtat ctatcattga tgaacttcca
     4141 gctggacgta tcccgatcga aacacgctgg gtaagaacac ctcaattgga cagtgtactg
     4201 gattggacga aaaaagaact ggcaagagga catcaaatgt atgtcatctg tccgctgatt
     4261 gaagaatcag aagcattaga tgtaaaaaat gcagtggaaa tctatgaaaa acttcgtgaa
     4321 ctatttgcac caaaatatga agttggcttg ttacatggta aaatgaagaa tcaggaaaaa
     4381 gaagtaatca tggaagcctt caaagacaac cagatgcaga tattagtttc gactactgta
     4441 attgaagtag gggtaaacgt gccgaacgcg accgtcatgc tgatcatgga tgcggatcga
     4501 tttggattgg cacagctgca ccaacttcgt ggacgtgttg gacgcggaag tgatgcttcc
     4561 tactgtatct tagttgctaa tcctaaaaat gaactaggtg tggaacggat gaaaatcatg
     4621 acagagacca ccaatggttt tgtactaagc gaaaaagatc tggaattacg tggtcctggt
     4681 gaagtatttg gcttccgtca atctggtctg cctcaatttg cgattgctga cttggtgacg
     4741 gatggaaatg ttttggaggt agccagagaa gaggctgcag ccctttggca aataaaggat
     4801 tggcagatgc ttcctgagta tcagccttta gcgcaaagcc tccaaataga aaatcaggat
     4861 aatcgttatt tcgattagca gactgtgcta tactttatac tgatgacgga aaaaggagtg
     4921 gaaacaatga aaattgccgt agatgcaatg ggcggagatc acgcacctca agcaattgta
     4981 gaaggcgtgg ctttagcgca gcaagatttt ccagaagtag aattcttact ttacggaaaa
     5041 gaagcagaaa tcaagaaata cttaacaaat gaaaaaaaca tcacgattat ccatacagac
     5101 gaaaaaatca atagtgatga tgagccagta aaagcaattc gacgaaaaaa gactgcatca
     5161 atggtccttg ctgcacaagc agtgaaaaac ggtgaagcag atgctgtatt ttcagcaggg
     5221 aatacaggcg cgctactagc agcagggttg ttcatcgtag gacgtatcaa aaatatcgaa
     5281 cgccctggct tgatgtctac cttgccagta gtagggaaag aaggtgccgg tttcgatatg
     5341 ctggatcttg gcgctaacgc agaaaacaaa ccagaacatt tgttgcaata cggtatttta
     5401 ggttcttttt atgcacgtaa agtccgaggt atcggacgtc ctcgtgtcgc actcttaaac
     5461 aacggaacag aagcaacaaa aggtagtgaa gtgacgaaaa aagcctatga actccttcag
     5521 aatgaaacaa gcttgaattt tattggaaac gtagaagctc gtgagctact caatggtgtg
     5581 gctgatgtag tggtcacaga tggatttaca ggcaacgctg ttttgaaatc tattgaagga
     5641 acagcaatga atatgatgaa tctattaaaa tctgctattc taaatgaagg gatcaaagga
     5701 aaaatgggcg ctatgctttt aaaagacggc ttacgttctt tgaaagcaga aatggattat
     5761 tccaaacatg gcggtgccgt tttgtttggc ttgaaagcac cagtcattaa aactcatgga
     5821 gcaacaggcc ccgatgctgt tcgctatacg atccgccaaa tccacacaat gcttgagaca
     5881 gatgtagttg gacaattagt cgaacaattt gaaaaaagcg aagaatagta tttggatatc
     5941 tgaagcgatc cgttccattg aaaaaaaggt ggacattcct gaaaaatgcc agtaaaatta
     6001 gccatggtgt aggtaattga caagtgtatg attcttggag gtgaaaaagt tgactcgcga
     6061 agaagtattt aacaaagtag cgaaaattat ttcaaatcat tttgagatag ataccgataa
     6121 agtgacggat gaattgaaca tcaaagatga tttaaaagct gattcaatta gtattatgga
     6181 attcgtttta gagcttgaag atgaattcgg tacggaaatt tcagatgaag acgctgaaca
     6241 aattgaaaca gtcggtggcg cagtagatta tatcagcagc catcttaaat aatttcaaat
     6301 aaaagcaaag aaggataaaa agctgcatgc agctttttat ccttcttttt ttaatctttt
     6361 tgacacgtaa aagtcatttt tctgataatt ctggcgataa acagaaatta tgttgcaaag
     6421 taaagcggtt ttctatataa ttattaataa ttcattacac aaagataaga ataacctttg
     6481 ttataaaacg atttattctg tgtaatgtcc ttttttatta agaaaaactt ccatttagga
     6541 agcagagagg ggtattcgat tgtccgataa ccaattatta gaagttcaga acctacatac
     6601 aggattccga ctcaaagatg actattacga tgcagtagat gacgtttcat ttactttaga
     6661 caaaaacgag attttagcaa tcgttgggga atctgggtgc gggaaaagta ccttggctac
     6721 tacgattatg ggattacttg atcctaataa cacaaaaatt acaggtgaga ttttatataa
     6781 cgatctgaat ttaatcgacc tgaacgaaac gctctataat aaaatccgcg gaaatgatat
     6841 cggaatgatt ttccaagatc cgttgtctgc attaaatcct ctcatgagaa tcgaagacca
     6901 gatcaaagaa ggactttcct atcacacaaa gatgaatgca gaacagcgtc aagctcgtgc
     6961 actagaattg ctagaacaag tagggattcc taatcctgcg agagttggac gccaatatcc
     7021 ccatgaacta tcaggcggta tgagacaacg tgtcatcatc gcaatcgcaa tcgcctgcaa
     7081 acctccaatc gtcattgcag atgaaccgac gacagcccta gatgtaacca tccaagcaca
     7141 gattcttgat ttactgaaag accttcagga agaaacaaaa acagggatca tcttgatcac
     7201 tcatgactta ggagtcgtag cagaaatggc tgatcgagtg gcagtgatgt atggcggaca
     7261 gttcgttgaa gtagcaggtg taaaagaact gtttgatcat cctaagcatc cttatacacg
     7321 ctctttactg aactctatac cacaagaagg aaatcatgat gcagaactcc atgtgatcga
     7381 aggtgtcgtt ccttctctga aaaacatgcc tcgtaaaggt tgtcggtttg caccacgtat
     7441 tccatggata ccagcaagcg atcatgaaga agagcctatc cttcatgaag tcgcaccgaa
     7501 ccacttggta cgttgctcct gctataagca tttccacttt agagacgaaa aaggagaggt
     7561 gtagatgaca gaattaatca caatcaaaga cctgaaagtt cattacccta ttcgcagtgg
     7621 attcttcaat cgagtaacgg atcatgtata tgctgtagat ggtgtggatt ttattatcga
     7681 aaaaggaaag acatatggtt tagtgggaga gtctggctct ggaaaatcta ctacgggaaa
     7741 agccgttgtg ggattagaaa aggtaacagc cggacaaatc atgtatgaag gaaaagatgt
     7801 aacgaagcga agcaaccgca aaaaaatggg ttataacaag gatgtgcaga tgatcttcca
     7861 agattcaatg tccagtttga atcctaaaaa gcgagtgttg gatatcattg ctgaacccat
     7921 ccgaaatttt gaacggttaa gcgatcaaga agaaaagaaa aaggtaaaag gactgctaga
     7981 tatcgttggg atgccggaag atgcgctata taaatatcct catgaatttt caggcggaca
     8041 acgtcaacgt ctaggagtag cccgtgctgt tgctaccaat ccaaaactga tcgtagccga
     8101 tgaacctgta tctgctctgg atctatctgt tcaagcgcaa gtattgaatt tcatgaaacg
     8161 aatccagcaa gaatacggcc tcagctattt attcatttca catgatttag gtgtagtaaa
     8221 acacatgtgc gacaatatcg caattatgta caaaggtcga tttgtagaaa tcggtacaag
     8281 agaagacatt tataatgacc cgcgacatat ctatacgaaa cgtctgcttt cagctattcc
     8341 gcaaatcgat gtagaaaata gggaaagcca caaagaaaat cgacgaagag tagaacaaga
     8401 gtatatccaa aaccaaaaag aatactatga tgcgactggt cgagtctacg atttgcgtac
     8461 gatcacaact acacacaaag tggcgttgaa agatggaggt gcaagctaat gtggaaaacg
     8521 attctgcgac gtgttttatt gatgatcccg caagttatta ttttaagtgt tctgatcttc
     8581 ttattagccc aagcgatgcc gggggatcca tttaccggtt tgatcaatcc aaatcaggat
     8641 ccggcagtga tcgaacagat gcgacaagca gctggcttga atgacccatg gtatgtccag
     8701 tacttccgtt ggatcggaaa tgctttgcaa ggcgattttg gtcaaagttt cttatacaaa
     8761 cgctctgttg ctgacttgat cggcgaacgg atcatcaaca ctttatatct atcgatcttg
     8821 acagttgtcc ttacttattt gattgctgtg cctctgggga tgcttgctgg ccggtatcaa
     8881 aattcaatct tggataagat tgtcgtaatc tacaacttct ttagttttgc tgttccttta
     8941 tttatcttcg gcttgatcat gctatttgtt tttggttatc gtttaggctg gttcccaaca
     9001 agtggatcac aaacactagg tttgcaaggt ggatttatca ctcaatggat agaccgtttg
     9061 aaatatattc tgttaccatc aattacccaa gcatttttgg cgactgccgt cacaatccaa
     9121 tatctgcgaa gtgaagtaat cgattcgaaa tcgctcgatt ttgtcagaac agcccgttcc
     9181 aaaggggtac cgacgaataa agtattcagt cgacatattt tccgaaatgc agcgttgccg
     9241 atggcttctc aaatggggta tgaaatcact tcgttgattg ctggttctgt agttatcgaa
     9301 aagatttttg gttatccggg agtcggaaaa ctatttattg attccatcgg ccaacgggac
     9361 tataccgtga tcacatcctt agtattgatt ttaggaatcg cgacgctagt ggggacatta
     9421 ctttcagata tcatcatgag tatcgttgac ccgcgtattc ggattcaata aaaccaatca
     9481 gaaaggagaa tggatcgatg agtgaaaaaa acaatacagc agttcaagaa agtattcctc
     9541 ctatggggat acgaatgatt gctcgagaat ttaaaaaaga taaaattgct attttttcat
     9601 taggtttgct agtggtttta ttattagtga tctttatcgg tgcgatgctg accgatcaag
     9661 acaaagtgat gtatgttagt atcttcgaca aatacgctgc accaggaaca gtttcgacac
     9721 aaggacaaaa gttcattctg ggagcagatg aaggcggacg tgatgtatta ggacaattga
     9781 tcataggtgc tagaaactct gttacgatcg gatttgcgat cacgatcctt acttcgatca
     9841 tcggggttgg attagggatc atctctggct actacggagg gatcattgac aacatcttga
     9901 tgcggatcgt tgattttatc atgattctac cgatcatgct gatcattatc gtcttcgtat
     9961 cgattatttc cagatacaat gtctggtcct ttatattcat catgagtgca ttttattggg
    10021 tagctaaagc ccgattattc cgaagcaaga cattatctga agcaagaaga gattatgtca
    10081 gtgcctcaaa aacaatggga accaatgatt ttaaaatcat gttccgcgaa atcatgccga
    10141 atctaagttc attaatcatt actaatttga cgatgaactt tgcggcaaac atcggtatcg
    10201 agacaacttt gactttctta ggtttcggct tgccggcaaa tgtacctagt ttaggtacat
    10261 tgatcggtta tgcaagtaac ggagaagtct tagtgaatcg gcaatggatc tggttacccg
    10321 catcaatcct tattttagtt ttgatgttga gtatcaatta tgttggacaa gcattcaagc
    10381 gttctgcaga tgcgcgccaa cggttaggct agtatagaag cgaaggggga aataggaatg
    10441 aagaaaacga tttttggatt tgcagcgctg atgtctgctg tcgttcttgc agcatgcggg
    10501 ggcggaggta cagatacctc tggaaacaac tctggaggca acggcaataa caaagaggaa
    10561 ttaacttttc caattgcaac aaaaaataat gatgatgcaa tcgaagacgg cgaattagaa
    10621 gctgcggtcg caacggacag tcagtttaaa ggattgttcc agtgggagtt ttaccaagat
    10681 tcatatgatg cagcttttat ggctccttct catgaaccgc tatttgcaaa cgatgacgat
    10741 ttcagaatca cagacgacgg agctgcaacg cttgatctag atgaagatac gaaaaaagcg
    10801 acaatcaaag taaaagacaa cgtcaaatgg tcagatggtg aagatgtaac ggcggacgat
    10861 gtgattttcc cttacgaaat cattgggaat aaagattaca ctggtatccg ttatgacgac
    10921 actttccgta acatcgtagg tatggaagaa tatcatgatg gaagtgccga cacaatctcc
    10981 ggaatcaaaa aaatagacga caaaacagtt gaaatcgaat ataaagaagt aaacccaagc
    11041 atgcttcaat cgggtggtgg tatctggtca tatgcagcac caaaacatac gttagaaggt
    11101 gtagcaatca aagatatgga atcaagcgat caagtacgta aaaatccagt gacttttggc
    11161 ccttattaca tgagtaatat cgttgcagga gaatcagtag aatacttgcc aaacgagcac
    11221 tactggaatg gtacgcctaa attgaaaaag atcacgatga aatctgtacc gatggcaagt
    11281 gcaactgaag cattgaactc taaattatat gatatgattt tccaaatgcc aacagatact
    11341 tacgatacct ataaagaaat tgctggctat acaaacttag gccgtgaaca aacttcttat
    11401 acttatctag gattcaagtt aggtaaatgg aatgcagata caaagagtgt ggaatacaat
    11461 ccagattcaa aaatggctga taaatcatta cgtcaagcaa tgggctatgc attagataat
    11521 aatgcagtag gtgaacgttt ctatgcaggt ttgagaagca atgcgacttc attgattcct
    11581 ccagtattcc agtcatacca tgatgatgag atgaaaggat tcacacaaga tctagacaaa
    11641 gcgaaaaaac tattagatga tgctggctac aaagatgtgg atgacgatgg tttaagagaa
    11701 gacaaagatg gaaataaact aacaatcaac tttgcttcga tgtccggtgg ggaaacagcg
    11761 caaccattgg cagattacta tatccaacaa tggaaagaaa ttggtttgga tgtccaatac
    11821 acaacaggtc gtctgatcga attcaattct ttctatgata aattagaaaa cgatgatcct
    11881 gaaattgatg tttaccaagc tgcttggaat acaggaactg atccaaatcc aagtggacta
    11941 tggggaccaa atgctgcgtt caactacact cgttatgaat cagaagaaaa tacaaaattg
    12001 atcaacgata tcagttcaag caaagcattt gatgaagagt accaaaaaga agcatatcaa
    12061 aaatggcaac aatatgcatt tgaagaagca tttgcgattc caacgttgtt ccgtaatgaa
    12121 gtattgccag tcaacgaccg tgtcaaagac tgggattggt cttatgatgt accaaaccca
    12181 tgggcaaatg tttctgttac agcagattca cgttcataat cactaaaaat gaccgaaaaa
    12241 gggcgatgtc ctttttcggt tttttgatat ttttctgttt atttctctaa tattcaggtc
    12301 aaggcgctga tttcatgact tctccaataa acggtgttca aagtccagtt tctcggtatt
    12361 aagtcaaatt tatgcaaaaa tatggaaagc cattttcaca aaattttttc ttcatactcg
    12421 aaactaaacg aatttttcac aacttctcgt caatcactag gattattaaa gctttactta
    12481 ccttttgacc gaaccatttc aaatttgaca aaaaaccagt ataataagga agtatcgaaa
    12541 aaatatccat aaaaggaatg tggaaaatgg acaaccagct gacaaaagaa ctaaaagaaa
    12601 actataacat cgtttttcac gatctaaatt tgcttgaaca agcttttacc cattcatcct
    12661 atgtgaatga gcatcgcaat ctgcaattat cggataatga gcgacttgaa tttttaggag
    12721 atgccgtttt agaactgatg gtttctcagt atttattccg tttatatcct catttgccag
    12781 aaggaaaatt gacaaaaaca cgagctgcga tcgttcgcga agacagcttg tcgaaatttg
    12841 ccaaagaatg tcactttgat caatatgttt tgttgggcaa gggagaagag aattcaggag
    12901 gacgtacgcg accagcattg ctttgcgacc tattcgaagc ttttttaggc gcgttatatc
    12961 ttgaccaggg attcgacacg acccatgcat tcatcgaaaa agtgattttt cctaaagtca
    13021 aagcaggtgc tttttcacat gagatggatc ataaaacaaa actacaagaa gtcttgcaaa
    13081 aatcaggtga tgtatcaatc gaataccgat tgatcaatga agaaggtcca gctcatgaac
    13141 gagtattttg gatcgaagtt tatgtagatg atcaattgat tggcactgga caagggaaat
    13201 cgaaaaaatt agcagaacaa gctgcggcgg aaaatgcatt ggcagcactg taaaagtaag
    13261 tgagggaaag ctttgtattt gaaacgaatt gaaatagccg gttttaaatc atttgcagac
    13321 aagacagtca ttgattttga aaatagcgtc acagcagtgg ttggaccaaa tggcagcgga
    13381 aaaagcaata ttacagaggc tatccgctgg gtattaggag aacaatctgc taaaagtctg
    13441 cgaggcggaa aaatgccgga tatcatcttt gccggttccg atacccgtaa gcagctgaat
    13501 attgcagaag tcacagtgat tttagacaat agtgatcatt atctgccatt ggagtacaat
    13561 gagatcagtg taacccgccg ttatcgacgg actggggaaa gcgagttttt catcaataaa
    13621 caaagctgca gattaaaaga tatccaagaa ttgttcttag attctggatt aggaaaagaa
    13681 tcgttctcaa tcatttctca aggaaaagta gaagcgattt tcagtagtaa accggaagac
    13741 cgtcgtggga tctttgaaga agcagctggt gtcttgaaat acaagcagcg gaaaaagaaa
    13801 gcagaacaga agctttttga aacagaagac aacctcagcc gcgtccaaga catcatccac
    13861 gaattggaag aacagttaac tcctttggcc gcccagagtg aggcagcaaa ggagttttta
    13921 cggctaaaag aaacactgac tcaaaccgat gtctctttga tggttgctga aatcaagaca
    13981 gcaaaaaaag attgggacaa caaacaagca cagcttgcga aattcaatct agaattaggc
    14041 aaactatctg agtcgatcca agaacaagaa tccattttgg cgaagcagcg taaagaaaat
    14101 gcgcaagccg atcgtctgat cgaaaaaaat cagcaagtat tattagatct ttcggaaaaa
    14161 ctgaagcaga cagaaggaca aaaagatgtt ttgcaggagc ggacaaagca tacacaaaaa
    14221 agctcgcaag aatatcaaac ttcattagca gaagcacaaa aaaaggttaa acattttgaa
    14281 aagcttcaag aaagcttgat gaaagcagca gcagaaaaag aaacagagat ccaaaaagct
    14341 gaagcaaatc tcataaaaac acagcaagaa ttagaaaaat accaaaaatc aacgaaagaa
    14401 ttattggcag aattaagaga tcaatatgtt gatttgatgc aagaacaagc agctgtagga
    14461 aacgaactga agtatctaga acgtcaatat atacaagaaa cagcaaaaag caagcagacg
    14521 ttagccaagc aatcggaagt agaagcatca gtagaccgat tgatcttaca aaaagaagaa
    14581 ttgacacaaa agcaggcgca gctaaaatca tctttaactg aaacaaaaga gaagttagaa
    14641 atgatccaac aaaacgggaa aaagttccaa gaagcattag caaaagaaca gcctaaaatg
    14701 tatcaattaa tgaatcaagt ccagcagcta cgtgctcgta agaaaagcct tcaagaaatc
    14761 caagaaaact attttggttt ttaccaaggg gttcgattgg tcttgcagca taaacagcag
    14821 ctttcgggta ttgtcggagc agtggctgaa ctgatcgatg ttcctgcaga tttcacgtta
    14881 gctatcgaag cagctttagg tggggcagcc cagcatgtca tcgttgaaaa tgaaaaagat
    14941 gctcggcaag ccatcacgta tttgaaacag caaagaggag gaagagcaac attccttcca
    15001 ctgacgacaa tcaaaccaag acaattaccg gctcatatat tgacacaagc agcagctgta
    15061 gaagggttta tagggattgc cagtgaacaa gtcagttatc ccgatcaaat ccaaactgtg
    15121 gttcaaaacc tgctaggaac gatcctttta gccaaagact taactagtgc caatgcaatc
    15181 gcgcaaacga tccgctatca atatcgagtg gtttccttag aaggtgatgt gatgaatgcc
    15241 ggaggatcca tgacaggtgg agcgaataaa cgaggaaacc aaggcagttt gtttgtacaa
    15301 aatcaagaat tgaaacagtt gactagtgaa tttgaagaag cagataaaca actccaagca
    15361 caagaaaaaa aagttcagga gctgcaacaa gaaacagctc gtttagccga agaacaagaa
    15421 gttttgcgta cacgaggcga acaattacgt tttgaagaac aagaagcgac aaatcagcta
    15481 caaaacatca taaatgaact tgaacgtttt gaaaaagaaa agcaaatctc aacttttgag
    15541 acacgtgaac tgcagcagtt tatcgaagat tacgaaaagc aaacgaacga attgaaagac
    15601 aaacaaacag atcttgaatc gcaacgacaa aaaatcgacg aagaaatcaa atcgttaagt
    15661 caagaaagcg accagatgga agccagaaga gcacaagtac aaagtcaaaa agcacaagaa
    15721 caagcagatc ttgctgtctt gaaagagcag tttaatcatc tgcagatcca gctccgcggt
    15781 gcccgagtcc aaaaagcaga ggcaaccgaa cgtcaagaag cgatagaaaa gcagttggcg
    15841 acattgacag cagacttttc tgatcatgaa gtcacagaag aaagtttgga aaaacaaatt
    15901 aacgaattat ctgctcagcg agaaacatta aaagccgagt tggcaaaagc caaagagcag
    15961 cgagatagaa ggcaaaagga gatcgataag cttgaagcag tcttggcaga gcgtaatcgt
    16021 gagcaaaaag cacgactgtc ggaacaatcc aaattagaag tccaaaaaga ccgagctgaa
    16081 atgattttag ataatcattt gacctatctg cagtcagaat atcagctgac atttgagaaa
    16141 gcttcccaag actatcaaga aacaaccgat atcgaagaca gtagaacaaa ggtttcatcc
    16201 ttaaaagaac agattgaaaa actgggacca gtaaacttaa attcaatcga acaatacgaa
    16261 caagtcagtg aaagacatac attcttagca acacagcgag atgatctgtt agcagcgaaa
    16321 aaccaattgt ttgaaacgat ggatgagatg gatgatgaag tgcggacaag attcaaagaa
    16381 gtatttgaag ctatccgtca agaattcaaa attgtctttc caaatatgtt tggcggcggt
    16441 aaagctgaat tagtactgac ggaaccaact gatttgctga aaacaggtat tgagattgaa
    16501 gtacaacctc ctggcaaaaa actgcaaagt ctaagtttgc tttctggagg agaacgagca
    16561 cttacagcca tcgcgttgct cttttccatt atccgtgtct gtcctgttcc gttttgtatc
    16621 ttagatgagg tagaagcagc gttagatgaa gccaacgtga aacgttttgg tcgttacttg
    16681 agcgatttcc aagatgacac acaatttatc gtagtcacac accgcaaagg aacgatggtc
    16741 gcagcagatg tactgtacgg agtgacgatg caggaatccg gtgtatcaaa aatcgtttct
    16801 gtacggatgg aagatatcaa tgaagaggcg aaaatcaacg aaacgaaagt gtaggaacga
    16861 aaatgatcaa attagtagca atcgatttgg acggtacatt attaaatgaa caaaagctga
    16921 tttcagatga gaataaacaa gcattagcac aagcaaaaca gcaaggggtc aagatcgttc
    16981 tatgtacagg acgcccctta gctgcgatgg cgcattatct gcaagaatta ggactggtag
    17041 atgaaggtga ctacagcatc actttcaacg gcggtttggt acaaaaaaat gatactggtg
    17101 aaatcatgga aaagaaagtg atggaagtat cagatatcca acgcttatac aaactggctc
    17161 agcaattgga tctgccacta gatgttttgt ctgacaatgt ggttttacag ctgcctagtg
    17221 ccccaaggaa gcaatccttg tacaatgtgt tgaataagct gctgcaattc caaccagcgg
    17281 atataagcga tattacagat gaatttgtgc ttaataaggc agtaatcgct tatgaccaag
    17341 aagaattaga tcctaaaatc aaagaaatac cagcagaatt ccatgaaatg tatgagatca
    17401 tcaaaacaag aagtatgctt ttggaattta tgccaaaagg tgttacaaaa gcttatggta
    17461 tttctttatt ggcaaaagat cttggtttga aacaagaaga aatcatggcg atcggtgatg
    17521 aggaaaatga tttaccgatg atccaatatg ctggactagg cgtagcgatg gagaatgctg
    17581 tgcctttcgt caaagaagca gcagatttcg tgacagccag caatgaagaa aatggcgtag
    17641 ccaaagtgat ccaaaaattt gtattagagt agggggagtc aaatgggatt ttttgataaa
    17701 atcaagcgtg cttttactgg cgaagagaaa acagaagaag ttgaagtaca ggagaagtac
    17761 gacaagggtt tagaaaagac gcgtaaaaca tttggtgaac ggatgaatga gttgtttgcc
    17821 aattttcgaa cagtcgatga agactttttt gaagaattag aagaaacact tatcggtgca
    17881 gatgtaggtt ttgaaacagc gatacgaatc accgaagcat tacgtcaaga agtgaaactc
    17941 agaaatgcga aaaaatcggc agaagtccaa aatgcgatca tcgagaaact tgtggatctc
    18001 tatgaagcgg aaggaatcaa tgaagtaaat gaactaaata tccaagaaga cggactaaca
    18061 gttattttgt ttgtcggtgt taatggtgta gggaaaacaa caagtattgg taaacttgcc
    18121 catcagttca aaaacgaagg taaaaaagta ttgatggcag cagcagatac cttccgcgct
    18181 ggagcaatcg accagttagt tgtctggggc gaacgcgctg gtgttgaagt tgttcgtggc
    18241 aatgcaggag gcgatccagc agctgtcgta ttcgatgctt tggaaagagc aaagacagag
    18301 caggcagatg ttttactagt tgatactgca ggccgactgc aaaataaagt gaacttgatg
    18361 aacgaattag aaaaaataaa acgagtaatc cagcgggaat taccagaagc accccaagaa
    18421 acacttcttg tattagatgc aaccactggt caaaacgcga tggttcaagc aaaacaattc
    18481 aaagaaacaa cagatgtgac cggtcttgtt ttgacaaaat tagatggtac agcaaagggc
    18541 ggtatcgtac ttgctatccg taatgaattg catttaccag tgaaattggt cggtcttggt
    18601 gaaggaatcg atgacttgga gccgtttgat ccaaatgatt ttgtcgttgg attgttcaaa
    18661 ggattactaa aagaagaata acccatgtct aaaaagcagg agctgtgaca aaagttgcag
    18721 ctccttgttt gaatgattgt ttttaacata gctgtgtttt tgatgccttc atttttatac
    18781 ttatttgtaa gcggttctca aacaatttcg ttctttttct tagacttttt gattataatt
    18841 agattcatat gaattggagg tcacttaatg atgaatttta agcaattatt attgcatgtc
    18901 aatgcgcgcc cttttatcga ccaagctcga tttggtatag aacgggaagg acagcgggtt
    18961 gatcttgcag gaaatctagc aaaaaccgat catccagcaa tctttggcga tcgatcctat
    19021 cacccctata tccaaacaga ttttagcgaa acacaaacag agatgatcac ccctgttacc
    19081 gattctattc ccgaattatt tcagtatctc gctgctgttt atgatgtgac tgctcgttct
    19141 ataccgaaag aagagatgat ctggccatta agtatgccac ctgccttacc ggaaaaagac
    19201 gaagagatca ttattgcaaa attaaaaaat ttcgaagatg tcttgtatcg acgttattta
    19261 gcaaaagaat acgggaagcg aaaacagatg gtaagcggta ttcatttcaa ttttgaattt
    19321 ggcgatgagt tgctaagaac attgttcagc catcaggaag aatttcaaga tttttccgaa
    19381 ttcaaaacag aactttattt gaaaacagcg agaaacttta tgcgctatcg ctggatgatc
    19441 acttatttat tcggtgcttc accaatgagt gagaagaact actttttaga tgaatcacat
    19501 ccgcaagaac ctgttcgcag tattcgcaac agtgcgctgg gctatacgaa tcatccaaat
    19561 gtgaaagttt cctatgcttc tatgaaacag tatttagcag atatcgagcg aatgatcgaa
    19621 gaagggaaac tttcggagga gaaagaattt tatacaccgc ttcgtttccg aggcggaaag
    19681 aaagtcgcag atttagcaac aacaggtgtt cgttatattg aattgcggaa tatcgatttg
    19741 aatccttatg caagattggg tatcaatcca gagcaagttc ggttcttaca attattcctg
    19801 atgtacatgt tatggacaga agaaaaagaa gactgtgacc aatgggtagc agaaggtacg
    19861 actcgaaata acaaagtagc actagaacaa ccatcagatc aaacagaatt tcatcaagaa
    19921 ggtagagaaa ttcttgaagg aatgaagcaa atgctggttg aattggattg gttggattct
    19981 ctttatttag tagaggaagc attgactcaa atggatcatc ctgaacaaac gttagcagcg
    20041 aaactctatc aagaagcaca gctatcgagt cagcaagaag ttgctgtggc attgggacat
    20101 caatattata aagaaagcca tgaacgtccc tatcagttgg ccggttttcg cgaaatggaa
    20161 ctttctactc agatatttat gttcgatgcc atccaaaaag gtgtccaagt caaagtatta
    20221 gatgagtcgg atcaattttt gcgtctgcaa ttccaagacc atgtagaata tgtgaaaaat
    20281 gcaaacatga caagtaagga cagctatatc gtcccactta tcatggaaaa caaaacagta
    20341 acgaaaaaag tcttaaaaga agctgggttc cgggtaccag gaggcgcaga attttcatcc
    20401 atggaagaag cggtaaaagc ttatccgaga tttgccgagc aggcatttgt gatcaaacct
    20461 aaatcaacca attacgggtt aggtatcacg attttcaagg aaggagctag tctggaagat
    20521 tatcaagcag gtttagccat tgcttttcgt gaagacagtt cggttttagt agaagaattt
    20581 atgccgggaa cggaatatcg tttctttgtg atcgacggag aagtccaagc catcatgttg
    20641 cgagtccctg ctaatgttat tggtgacagt atccgaacag tgaaagaact tgttgaagaa
    20701 aaaaatagtg accctttgcg tggaacgaat catcgtgcac ctttagaatt gatccaatta
    20761 ggtgaattag aacaattgat gttgaaagaa caagggttga cgatcgaatc agttccccaa
    20821 gccaatcaaa ttgtttatct aagggagaac tcaaatatca gtacaggtgg tgattcgatc
    20881 gatatgactg atgaattttc tgaagcttac aaaaaaatcg ccgtttctgc ggtagaagca
    20941 ctaggagcta agattagtgg tatcgatttg attataccag ataaagaaat cgatcctaca
    21001 actgataaaa aagcatatgg gatcatcgaa gcaaatttca atccagccat gcatatgcat
    21061 gtttatcctt ttgcaggaaa aggcagaaga ttgacgatga atgtattgaa attgttatat
    21121 cctgaagtat tttaaaagaa aaagcttttg acagattgtc ctatttgatg tcaatctgat
    21181 caaaagcttt ttttgcatgt aaaaatttat gtgttttttc gttttaaaat aaacgatccc
    21241 agaagctttt tttctttttt ggtttttctt tttcagctgg cgaagagttt tcttctgggt
    21301 attttttttc gatatcaatc acaggttcat ttactgcttc ttttgctgtt aagagcaatc
    21361 cgaattcctc aggatttgca gtgacgtaat cgttgactac agtgaaacgg ctattgtttt
    21421 tcgttgctag ctggatatat tggttttgga cagaaagggg tagagcccca ttcaagagta
    21481 tggaagcatc tggatgtttt ttgagttctt ttaaaaagtt ttctttgttt tttggttgga
    21541 tcatttcagc aacagtcata ctaagatagc agcgttccct gaatgtccct aaatatttat
    21601 gctgttcttc agggttcact aaaggtgtac cataaagtcc cttatccaaa tggcttttta
    21661 catcatcttg tgccataaaa aataccctcc ttcttctctt tgtctttctt acgattatag
    21721 catattccca ataataccta aaacatatga aaaagcggtt gcttttgttc aacgattcac
    21781 ttaaaataag aatgaaaatc attctcaatt agaaaggtgg attggatgcg ctacggacga
    21841 ctagtagcat tattagttat tttaagtagt atttcattgt tcatcggagt atcgaatgta
    21901 caattgtcag aactgctcca gttagatggg caaagcttac aaatcttgct agtgactcgt
    21961 ttgccacgaa cgatttgttt gatccttgtg ggagcgacca gtagtatttg tgggttgatc
    22021 atgcaacatt tgacccaaaa taaatttgtt tcaccaacga ctgcgggcac gatggatagt
    22081 gcgcgtttag gtattttagt ggctatgatt ttcctacctg gtgcatcctt gattgtccga
    22141 tccttgacag cattttgctt tgcttttgca ggaacattgc tttttttatc ccttacgcga
    22201 ttgttcctcc agaaaaatca attgatgctt ccgttgattg gagtcatgtt agggaatatc
    22261 attggttcag ttgctacttt ttttgcttat caattccagt tggtacaaaa tatgacttca
    22321 tggcttcaag ggaattttgc gactgtgata cgaggaaatt atgagttatt gtatgctgtt
    22381 gttccattgt tgctcttggt ttggctattt gcttaccgat ttacgatcat tggtctgggc
    22441 gaatcgtttg cagtaaatct gggaatagat taccagaaga tgcagttttt aggcattggc
    22501 ttagtatcat tggctagtgc agtcatgttg atcatggtag gaagcattcc ttttatcgga
    22561 gtgatcattc cgaatcttgt ctctagaata tatggagatc aagtgcacaa aacaattggc
    22621 gtaactgctt tagcaggtag tttgttctta gtattttgcg atcttgtcgc tcgcgtgttg
    22681 atttttcctt atgaaatacc agtcagtgtg atcgttggaa tcatcggtgg ggctatcttc
    22741 ctttatcttc tgataagggg acgacgatat gcttaaaaaa aagccatcta tttttattgg
    22801 tatgcttgtt cttgttttat ttgttacagg aatgtacttg acgatccata catatggaaa
    22861 ctggcatttt gcatgtgcat tgaggagtaa gaaaattttt gcatttatcc ttgtctcgct
    22921 agctgtcagc agtgccacaa tcagctttca gacaattacg cataaccagt ttttgactcc
    22981 ttcagtattg ggacttgagt cgttatatgt ccttgtccaa acggtccttt tcttctttat
    23041 cggaggagtg acgatgcttc agcagacagg tacagttttt ttcttattga acgttgggct
    23101 gatggtcggg ctgagtctat tgttattttt ctttcttttg aaaaaaatga gagcgaatct
    23161 ttttttatta ctgatgtcag ggatgatttt aggtacgctt tttggtagtg tcagtacctt
    23221 tttacaagtc atcatggatc cgaatgaata tgatttgctt caaggcagat tatttgcaag
    23281 ctttggcaat atccagagtc agtatctttt gcctgcttct ttgatcatta tcggctgctg
    23341 gtacctgtta tttcgatatc gacatgtgct agacgttttc catctcggaa atgaacaagc
    23401 agtaaacctc gggatagaca cagatcgttt tgaatttttg attttatgtt gtgtcagtct
    23461 tttgacaggg acatcaacgg ctcttgtggg tccagttact tttttagggt ttattgtcgc
    23521 aaatatcagt tatcgtgtct tttctactta tcgtcatggt cagctattta tcggaagctt
    23581 tctggtagct atgctgtttc tgacaggagg acagctcgca gtagagcaga ttttcggctg
    23641 gaatacaaca gtgagtgtcg tcgttgaatt tgtcggagga atttattttg tcacaaaatt
    23701 gattcgcgaa aggaagagta tcctatgatt gatttacaaa aggtcaataa actgtaccat
    23761 ggaaaatcag tggttaaaga tgtacagtta acgattcctg aaaagaagtt gactgctttt
    23821 atcggtccaa atggtgctgg aaagtcaacg gtgttgtcga tgatcagtcg tttgatacca
    23881 aaagatacag gtgaaatcta tttagaccat aacgaagtaa aggcttggaa atccaatgaa
    23941 ttagccaaaa aattatcgat cctacgacaa tcgaatgaaa taaatgtcca aatcaccgtg
    24001 aaagaattag tagaatttgg acgatttcct tatacgaaag gaaaattgac gacaaaagac
    24061 gaggaaatcg ttcaggaatc actggaacac attgggttag aagaaatagc ggatcaatcg
    24121 attgacactc tttcaggcgg tcaactccaa cgtgcgtata ttgcaatggt gctagcgcaa
    24181 gacacggatt atattttact ggatgaacct ttgaacaatc tagatatgaa ttttgcggtt
    24241 caaatcatgc agattttaaa aaatttagta caagaaatcg ggaaaacaat tgttattgtt
    24301 cttcatgata tcaactttgc tgcaagttat gcagacgaaa ttgttgcaat gaaagatgga
    24361 cagttattta cgcaaggaac gacccaagaa atgataaaaa aagatgtatt ggatgaatta
    24421 tacgaaatgg acatacggat ttgtgagatt gaaggccgca gattctgtct ttatttctaa
    24481 aactaacatt aggagagaag agatgaaaaa attagtagta ggtatcttga ttctagcatc
    24541 atttggttta gcagcatgtg gaaatagcaa caacaccagt caggcagaca caaaaaaaag
    24601 cagcacacaa actgaaacta cattgacgat aacagatagt aatggagacc aaatcgaggt
    24661 gccaaataat ccagaaaaag tcgtcgtatt cgacaatggt tctttagata cgatggatgc
    24721 tcttggtgtt ggagataagg tagttggagc agctacaagc agccttcctg agtatctttc
    24781 atcctataaa aaagtagaat cagcaggtgg aataaaagaa ccagacttag aaaaaattaa
    24841 tcagcttcag ccagatctaa tcatcatttc tggccgacaa agagattttc aaaaagatct
    24901 aagtcaaatt gctccgacca ttttcctttc tttagatgcg aaaaatccat gggaatcttt
    24961 ccagcaaaat gtcactgctt taggggagat ctttggtaag caagaagaag ctaaaactca
    25021 attagaggaa ttatctagtg caatcgatca gacgaaaaag aaagcagaag ctactgacaa
    25081 aaaagcacta gtcacacttg tgaatgaagg gcaattatca gcctacggat ctggttctag
    25141 attcggtttc atccatgatt tatttggctt tgaacaagca gatgatcaaa tcgaagcatc
    25201 cactcacggt caaagtgttt cttatgaata tgtgctggaa aaaaatccgg atatcttatt
    25261 tgtagtagac agaacaaaag ctattggtgg agacgacagc aaagatgata tttctgccaa
    25321 tgaactggta gcacaaacga atgctggtaa aaatcagcag atcatctccc ttgaaccaga
    25381 tgtctggtat ttaagcgggg gcggtttaga atcaatgaaa ctgatgatcg aagatgtgaa
    25441 tcaagcattt aaatagcata aataacagag gattaaactc tcatactatg taacaataat
    25501 gtttcttaca ttcttaaata gcaagagcct atcctcaaag aagttatcaa aaaccatccg
    25561 taaaatcgta ttgatgattt tacggatggt ttttatttat ttgagaaatc ttttttcaac
    25621 gtgaattcat tatctacatc atacgggttg attctagaat ggggagtggc aaaaaatagt
    25681 gtgatccatt ttttcagcat caagatcgcc tcctttgatt tgaatcaaag gtacaaagcg
    25741 aaacttagat aaaacttaaa tttagatatt tttattttgt accgatctct tctttaaacg
    25801 atgttccatc tgctgcttct cggcaataag tccactagac tagaaaatat gagaagctat
    25861 tttctgtcca gcgttcttat tactcaaaac aaatcgcagt tgtcacaatc tcttctaaac
    25921 gatgttccat ctgctgcttc tcggcaataa gcccactaga ctagaaaata tgagaagcta
    25981 ttttctgtcc agcgttctta ttactcaaag caaatcgcag ttgtcacaat ctcttctaaa
    26041 caatgttcaa tcagctgacc ttcggtatta gctcaaagca ctgatttcac aacctctatt
    26101 taggcatgtg tctcagcaag cggttgatag ttgatgatct gcatttttcg ataaaaatcg
    26161 gcgggaagct tactccaccg ttttagtaat tgatagaaat aactctcttc tgctttgatt
    26221 ttatactcgc ttaatatcaa tccaaaacta ttcgtttttt ttgaagctaa ttttttataa
    26281 atatccaatg ctttggtttt atcttcattg acaaagagtg tttttacttc aatataagaa
    26341 ccctcgatat tttgtgtttc ttcgataaaa tagatgtttt ttatatattc cttcatagtg
    26401 attcctccaa agaagtcttt tatttgataa gtttactcta ccgaagagtt gttaataatc
    26461 cgtgaacaaa aagtaattct ttttccaata gttgttaaag gttttttatt ttttatagta
    26521 ttttttgtta tttaagaaag gaataaggtt aaacaaataa caggttgctt tttgggtctt
    26581 tttccgttca agaaactgaa cgaagaaaag ggaaagttgt ctcttttgtg ataagagaaa
    26641 tcataataaa cgaatgactt actttccaat aaattgagaa cagtcagaac cagacaaatt
    26701 agttgcatct gatgaataaa gtgattattc tatgacatga ggtgatacag atgaaattag
    26761 aagtgacaaa agaagcacaa gaagtattga agaataaatt agaagcagac gatcaacttt
    26821 tattagatat cgaaaacggt gacggtccat ttgcagaaag ccaagtcagt tgccaattgg
    26881 atacggcatt tcgattgatc attgtcaaaa aagatacaca aacagatcta agtctttatt
    26941 ctgtagtggc tgatacacca gttggaccaa tcaaaatcaa agacagtgca atactttaca
    27001 tggatgatcc atccacactt gctttagaac caacttataa tagtttacaa ttaaaaggac
    27061 caagcggctt gagaaaaggc aacttgcaag ttgttcgaaa agactagagg gataaaatgg
    27121 gaaaattggc gatcatcagc gacctacatg tggacatcaa taaattcggc gaatcagagc
    27181 tgatgcagct ttggcaagtt ttgcaaaagc acaagatcac tcggcttcat ctagccggag
    27241 atacggctaa taaagtagac cgttgcctag ctgttgtcga atttttcgtc aataaaggat
    27301 tatctacgac atttcatttc ggcaatcacg agttggcaga tgtgcccaat gaacagatga
    27361 tggaccattt tccagaccca cattttttaa atgaacggta tattgcttta aatgagcaga
    27421 ccgttctttt agggatgaat ggctggtacg actatcagtt ttccgaattg aaagattacg
    27481 aggcaatcgt acgaatgaag cgtttgtatt ggtatgatcg gttcatccag cgtgggaaaa
    27541 cagatctcga ggtcaatgca gaaatgcttg cagctgcaaa aaatttgcta gaccagctgg
    27601 aagcaaaaaa acttgaggtg attttatcca ctcatttcgt tcctaaacgg gcatttatca
    27661 tgtatcaatc tgctccttat gagcgttgga acaaattaaa tgcattttta ggatcagaat
    27721 cattcggaga attacttgac cgttattcaa atatcaaaca agtagttttt ggccatacgc
    27781 atcgtcgctt tgaagataaa tccatcggtc acacgattta cagctgcaga ccttttggtt
    27841 attattatga atggcagctg acccgagatt ttgtcttgaa agaacagttg ctagacagct
    27901 atgatcctat gaaattacgt gtcctcttgc gtgcccatca cccagctttt caggcctatc
    27961 aaacacaaca tttgcaagag gaatttgaac aagcgatgac aatcgttccg tattgagaca
    28021 gcattagtaa tgtgtaaaag aaaatacctt gtaaaacata aggataagta agagcagtag
    28081 atccatttat cgtggatatg ctgctttttt tgcggaaaat aatcagcgaa tgtttatttg
    28141 atcggatgat ttgtaactcg cagagtacta gatgcaagcg tgtattcttt ttttgaacga
    28201 taatcacaaa aaaaaatata atatacattt tttatttaat tataattaat attgattgaa
    28261 gtctaggcag tcaagtcgag agtgtaaaat attttgtgta aatgaaaaaa tccatacaaa
    28321 aaaggaagtc
//
LOCUS       DBBGSZ010000035        28029 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.035, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000035 DBBGSZ010000000
VERSION     DBBGSZ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 28029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28029
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.035"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            184..1182
                     /locus_tag="ACIZE5_002032"
     CDS             184..1182
                     /locus_tag="ACIZE5_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGC6109150.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1294..1803
                     /locus_tag="ACIZE5_002033"
     CDS             1294..1803
                     /locus_tag="ACIZE5_002033"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HGC6109151.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1833..2492)
                     /locus_tag="ACIZE5_002034"
     CDS             complement(1833..2492)
                     /locus_tag="ACIZE5_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HGC6109152.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2494..3258)
                     /locus_tag="ACIZE5_002035"
     CDS             complement(2494..3258)
                     /locus_tag="ACIZE5_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HGC6109153.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3266..3943)
                     /locus_tag="ACIZE5_002036"
     CDS             complement(3266..3943)
                     /locus_tag="ACIZE5_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HGC6109154.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3980..5365)
                     /locus_tag="ACIZE5_002037"
     CDS             complement(3980..5365)
                     /locus_tag="ACIZE5_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HGC6109155.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5575..5659)
                     /gene="ffs"
                     /locus_tag="ACIZE5_002038"
     ncRNA           complement(5575..5659)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACIZE5_002038"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5682..6197)
                     /gene="tadA"
                     /locus_tag="ACIZE5_002039"
     CDS             complement(5682..6197)
                     /gene="tadA"
                     /locus_tag="ACIZE5_002039"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HGC6109156.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6304..7161
                     /locus_tag="ACIZE5_002040"
     CDS             6304..7161
                     /locus_tag="ACIZE5_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6109157.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7242..7577)
                     /locus_tag="ACIZE5_002041"
     CDS             complement(7242..7577)
                     /locus_tag="ACIZE5_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109158.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7644..9014)
                     /locus_tag="ACIZE5_002042"
     CDS             complement(7644..9014)
                     /locus_tag="ACIZE5_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HGC6109159.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9092..9628)
                     /locus_tag="ACIZE5_002043"
     CDS             complement(9092..9628)
                     /locus_tag="ACIZE5_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6109160.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            9937..11418
                     /locus_tag="ACIZE5_002044"
     CDS             9937..11418
                     /locus_tag="ACIZE5_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6109161.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLIKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(11521..12228)
                     /locus_tag="ACIZE5_002045"
     CDS             complement(11521..12228)
                     /locus_tag="ACIZE5_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HGC6109162.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(12307..12645)
                     /locus_tag="ACIZE5_002046"
     CDS             complement(12307..12645)
                     /locus_tag="ACIZE5_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HGC6109163.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(12756..13718)
                     /locus_tag="ACIZE5_002047"
     CDS             complement(12756..13718)
                     /locus_tag="ACIZE5_002047"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HGC6109164.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(13733..15064)
                     /locus_tag="ACIZE5_002048"
     CDS             complement(13733..15064)
                     /locus_tag="ACIZE5_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DRTGG domain-containing protein"
                     /protein_id="HGC6109165.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(15072..15752)
                     /locus_tag="ACIZE5_002049"
     CDS             complement(15072..15752)
                     /locus_tag="ACIZE5_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HGC6109166.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(15971..16450)
                     /locus_tag="ACIZE5_002050"
     CDS             complement(15971..16450)
                     /locus_tag="ACIZE5_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HGC6109167.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(16577..18256)
                     /locus_tag="ACIZE5_002051"
     CDS             complement(16577..18256)
                     /locus_tag="ACIZE5_002051"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGC6109168.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            18804..20306
                     /locus_tag="ACIZE5_002052"
     CDS             18804..20306
                     /locus_tag="ACIZE5_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6109169.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            20319..20981
                     /locus_tag="ACIZE5_002053"
     CDS             20319..20981
                     /locus_tag="ACIZE5_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6109170.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(21082..21285)
                     /locus_tag="ACIZE5_002054"
     CDS             complement(21082..21285)
                     /locus_tag="ACIZE5_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGC6109171.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(21396..22580)
                     /gene="iadA"
                     /locus_tag="ACIZE5_002055"
     CDS             complement(21396..22580)
                     /gene="iadA"
                     /locus_tag="ACIZE5_002055"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008798 - beta-aspartyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HGC6109172.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(22737..24476)
                     /gene="yfcC"
                     /locus_tag="ACIZE5_002056"
     CDS             complement(22737..24476)
                     /gene="yfcC"
                     /locus_tag="ACIZE5_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HGC6109173.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(25249..25863)
                     /locus_tag="ACIZE5_002057"
     CDS             complement(25249..25863)
                     /locus_tag="ACIZE5_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGC6109174.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(26469..26846)
                     /locus_tag="ACIZE5_002058"
     CDS             complement(26469..26846)
                     /locus_tag="ACIZE5_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109175.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(27146..28027)
                     /gene="galU"
                     /locus_tag="ACIZE5_002059"
     CDS             complement(27146..28027)
                     /gene="galU"
                     /locus_tag="ACIZE5_002059"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGC6109176.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT         8324 a         5873 c         4685 g         9147 t
ORIGIN      
        1 tttgcatact tcataataat aataacataa tacctaacct ctcgtaaaaa tactagattt
       61 gttttctttt atttttcatc actagataca ttctataact taccgtttcg atttcgaatt
      121 caaacatttt tgagaagcat tctcaattaa attctgatat agtgtgaaaa gggaggaatt
      181 tttatggaaa tctatgacat tacaatcatc ggtgcaggtc ctgtagggat gtttgccgct
      241 ttttacgcag gaatgcgcca agctaaaaca aaaatcattg acagtctacc tcaacttggt
      301 ggtcaattag caactttgta tcccgaaaaa tatatttacg atattcctgg gtatccagca
      361 ataaaagcaa gtgaattaat cgatcaatta gaaaaacaat taactacttt taaccataca
      421 ttccatttaa aagaagaagt tctctcgctt actcgtgaag acgaagttat cgagattact
      481 acaaataaag gcatccatta ttccaaagca gtcattttag ctttaggaaa tggttcattc
      541 cagccaagaa aattgaattt agataatgct gaatcatttg aaaaccacgg attggattat
      601 ttcgtgaatg atttgatgaa gtatgctgga aaaaaagtcg ctattgctgg aggtggtgat
      661 tctgctatcg attggacgtt gatgttagag cctattgcaa gcgaagttta cttgattcat
      721 cgtcgcccgg aatttcgtgc gcacgaacat agtgtatcac gcttgaaatc ttcatctgtc
      781 aacttgctta ctccctatct catcgatgga ttatcaggca ataatgggga actgacagat
      841 atccggttaa aaaaagtgaa aagtgacgag acgattgatt tgatgattga ttctctgatc
      901 gtcaattatg gattctcttc taatttagaa catctttctt cttggggact tgatagtacc
      961 agaaatgcca ttactgtaaa atcagatatg tctacttcta ttccaggcgt ttatgcagct
     1021 ggtgacatct gtacctatga aggaaaagtg aaactgattg ctactgggct cggtgaagca
     1081 cctactgcag tgaacaacgc tttacactat attaatccaa aggaacgaac tcagcctggt
     1141 cacagcacaa gcttatacga taaaaatctt cgtcctagtt gattttttat atctctttgc
     1201 atttcaagtt aaacccgaaa gcagtttctt gcattttttt catgttccgt taacatgaaa
     1261 tagagaaaga aaaaataaag ggggagcaat aatatggtcg tcaaaactga gactttagaa
     1321 gaaaaggcaa gagaactatt gaaggaacgt ggcgtaactg tagaagatat cgcacaactt
     1381 gtcatgtttt tacaaaaaga ctatatttct gatttgactt tggcggattg tactgaaagt
     1441 gtcaacagcg tgctaacaaa gcgtgaagta cataacgcca ttatcactgg aatccaatta
     1501 gatatattag cagaaaagaa aaaattgatg agtccgttgc aacatattat cgaagatgac
     1561 gaaggccttt acggtatcga tgagatccta gccttgtcaa tcgtgaatgt ttacggtacg
     1621 atcggcttta cgaattatgg ttatatcgac aaggtgaaac ctggtatttt aaaagaacta
     1681 aacagccacg atggcgttca tgtccatacc ttcttagatg atatcgtcgg agcgatcgcc
     1741 gctgctgctg ccagtcgatt agcacacaaa gaaccagaaa aaagaagtcg ccttactcaa
     1801 taattcaaca aaaaaagaaa gaaaacgtct atttagacga gttctttctt ttttgtttgt
     1861 ttcaagctat tttttcctaa gaaaagaaaa acagcaaaaa ataattctaa taatacaaaa
     1921 aataagataa agctatgcat gaaaaattct tctggaagta cattgatgat tggatcagta
     1981 acgggatcga ataaccagtc atcgttgttg aaaaacgttt catgaaaaag gataaaaaag
     2041 cgatcaaatc ctatcatcat gaaaaaaccg aaaacaactg gcagtaacat gccgatttga
     2101 aacggacgaa tcaaccgcca aagccgatca ttcttttgca aatatttgat aaacaaaata
     2161 ctcgggatca aagtgatgaa aaacacagca taatccacta aaaacaaaat tttcacttca
     2221 taaaagtgat gggctccgct agcagaaact gggaaatctg gcaagctgag gatggttttg
     2281 aagggattat tgagataatt cattaggtga tcaaaatttt tcagtaacgt ctcttgatct
     2341 aaagaagtat aatccaaaat ttgcaaatgt ccgatatcaa atacgtatag tggtcgaaag
     2401 ttgatcgtca caccaactgc cagactgatc agtgtcagaa ataggctgaa caatccagca
     2461 tattccatcc actgccatct cgaatttttc atattagaag ctccattcat ccagtgattg
     2521 tttcacatag gtagctggga taggcaaccc aggtacatct tcttcttttg taaaacctga
     2581 taaaacgagc aaagtatcta tattattgcg tatcccagct tggatatctg tttcatagtt
     2641 atctccaacc atgattactt cttctttttg cagccctaat acttcaacgg ctttatccat
     2701 aatgatggct tctggttttc cgatgtagat cggcggcgtt tgggttgctg tctctacaaa
     2761 agagatgact gaccctgctc caggaagaag gccgcgttca gtaggtatat tcttatctgg
     2821 gttcgttcca atgaaagtag cacctttttg aatagcaagt gttgctttaa ctactttttc
     2881 ataggtcaga taattatcta agcctaccac tacatagtca ggagcctctt cttcccatgt
     2941 aaatccggca gctaaaatca agtcaatcaa tcctgcttct ccgataacat agactttttt
     3001 cccttttcca tctgctttca taaaatcgat tgttgccaaa gtagctgtgt agactgtctc
     3061 tggagctaca tgaatgtcaa actcatctgc tagacgatta gctactgttt ctggtgactt
     3121 agtcgtgtta ttggtaacaa acaagaaagg taattttctt ttttgcaatt cttccacaaa
     3181 tcgtttaccg gccggtatgg gttgtgtccc acgataaatc gttccgtcta aatcaattaa
     3241 atatccttta tagtccattc atccactact cttccctttt tctgatcgta aatgctgttt
     3301 ttgttttttc tacttgttta ggttgttctt gtttttttac tttttcagag gtttttgctg
     3361 actctgtttt tcgattttta ataaccggtt ttttgcgatt agatgcgact ggtccttttt
     3421 tctcatcgat atacgcacga ttatggtttt ttttcttttt tcggcgctga gttgtctttt
     3481 cttttttacc gccgattctc tcgatgacaa aatacgcaca accaaaattg caatattcgt
     3541 aaagatagtc ttccaaggaa tcgattcgct gatctggatg cgcccgtcga ttatccgctt
     3601 ggaaaaatcc ttttaggcgt agttgttcat aaccccaatc tcctacgata taatcatatc
     3661 gggctagtac atcactgtaa cgttctccaa gcttttctgc attaaatcct tcacgataat
     3721 cggacacaag ccgataatgt ctttcaccta tcaaaaaatt actgtcatct aacagtgtca
     3781 ctagctcgcc tttgactttt tctgctttag gctcctcaac gatttcttcc aaagcagctg
     3841 tcagttcttc ggtgactgtt gtttcctgtt cagctgatga ttttttctta gcaatttctg
     3901 ttttatgctc aacgttctgc tgttcatttt gttttgcaga catgcgttca ccacctatct
     3961 tttttattat accttgtttt tatttgattg ggtagtgagc tttcaagtaa tctcctacca
     4021 cacttcggat aaattcaggg aacaaaaatt cattttttcc agcaatctca atcgttggaa
     4081 aaaatggaac aaacatcaaa tgatctacgg tagtaaaagt ataattttta ttcagatcga
     4141 ttggcttgtt cttccaaaag acttgatggt taatagaatc atatgtgatt ccattataga
     4201 ccatctgccc aaaaatctta ccgcgaaatc ccattccctt cataggatag ttacgtaaaa
     4261 agttacgatt tttttctatt tctaaaacta agcggatcag atcatttcca cccaatgtga
     4321 catttaacaa gtgcatcgga tgcggcaacg cagtgtgaag ctgatcctga ttgacccgcc
     4381 cttttggaat ttcagttaaa aacagaccac tgtttaatat tgctgcttcc gtctttcctc
     4441 gttctttcac cgcctcaaag gctacttgga taaacgaatg ctcattgaag atatctagac
     4501 tcagagaaaa tggcaaatct gctacttctt tttcttttaa taattcatgc ccacgttcta
     4561 gataactatt tatttcttgt tcatcttctg taaaagctgt cattgtttcg gtagggatgg
     4621 ctttggctga atgcttaagg atttttttct cttcatcgat ggttaaatgg acttcaccga
     4681 catactgccc gtactttcca gcggctgcta tttggacatc attgattacg tgaccttctc
     4741 tgaataaatg atgggtgtgc gatcctaaaa taacatcaat tgctggtatt tcttttgcaa
     4801 tttggaaatc atcctgaatc ccgagatgac tcatcaaaac taaaacatcc acttgtgaac
     4861 gtaaatcttc gactaattct ggcaaaatat cataaggatt ccgtatgtcc cagccattcg
     4921 gattataagt aagcggaaat ggagcagtaa atgcaattag tccgattttc gtctggtgtt
     4981 tcgttgtaat gattttatat ggtttcgtcc atgccggtgg ctggagcgta tttttatcga
     5041 ataagttatc caggatgata tcaaactcag catgatcgta taaatgattc aactcttctt
     5101 tggaatttcc tacgccttca ttgtttccta tcgtcgctgc atcataacca acttcattca
     5161 tcagcaagat attttcctgt ccattcgttg cttctgacaa tggatgccaa cgatccacaa
     5221 aatcacctag atctactgca atcgttgtcg ttttttcttt cttttcgttt tctcgtttac
     5281 gttgatccaa aaaccttctg atccttggcc aattttctaa atgagaatgc agatcattcg
     5341 tatgtaaaat cactattttt tccatgtacc ctctcgcctc tctttatctt tatcatacca
     5401 taggcagctt tttcttccat tgaaacaagc tctatttcag agtttttcct gccttgaagc
     5461 aaattgtata agtacaatat tcgataaatc agtctggcta aaaaatcagg aacattcatt
     5521 tttacagtac tataaaaata aaaaaaacag acccgaaagt ctgttgtcgt ttcattataa
     5581 tcagacacat ggcggaacct gcttagtgct gcttccttcc agacctgaca cgcttcacaa
     5641 gcccaccatt gtcctagcct ttcggcaaag aatagtatac cttatttttc attcgttgac
     5701 cagtcttttt ttaatttctt ttttcgctgg cggagctttc ggaaaaagtc agtcaaaatc
     5761 atcccacatt cgtcttctaa aatgccacct tctacatatg cttggtggtt aaaccgctcg
     5821 tcctccaaaa gattcatcaa ggtaccggct gttccgcctt ttggatcata cgcgccgaaa
     5881 taaacttctg ctacacgaga caaaatcatc gcgccgctgc acataggaca aggctctaag
     5941 gtaacaaaaa gtgcagcatc ttccaagcgc cagcttccca ctttttcaca ggcttccttg
     6001 attgcaagca tttctgcatg tgtagtagca tcttgcgtgg tttctctaag gttatatcct
     6061 cttccaatca cttttccatc caatacaacc actgctccaa tcggaacttc atgaagcatt
     6121 tctgctttct ttgcttctgc caatgcaagg cgcatccatt tttctttttc tactgcatca
     6181 agatttgtat ttaccaatta cccttccctg cctttgtttt ttcttgtttt actttagcat
     6241 atgataaaaa ggctgtaact aacttttttt tctatggtaa aataaataca agaggtgaac
     6301 aagatgaaaa tggataaatt acttgctctt tacccacaag cacagaaaaa aaactctcca
     6361 gcatcagaag cggatatcct ttcttttgca attgatgatg cttttatctg gatcaaacaa
     6421 gattcattat ctcaacaaga aaccagcctt ttgaaagcgt tattccctgt aatcaacgat
     6481 caaaaaaaac acccatggta tcactatctt tttaaagatg cttcttgtgt tcaagaaaaa
     6541 agctttcgtt tgatccagct tcacgtcgaa tcaaaaggag aattcttaaa aaaagaatgg
     6601 caagatacta ttttggaatt atttcgctat tctgctgatt tcttttttta tacagacaca
     6661 gatgcgctct tagtcgaaca aataaaccgt gattatcttg atgctactga aatcaacggt
     6721 atttttctat ctttagatgc tgattttgat acgacaacgt ctgtattcgt tggttctttc
     6781 cattcacctg gcaccgacct cgtccctttg tttgctgaag aaagaaaaat ttttttaaca
     6841 gagcaaaaca atctttatac tcacagccgt actttttcta tgcaagatgt ggctttacat
     6901 tactatacaa aagatactgt aaaagatagt aagttgatca aaagttacat agaactgatc
     6961 aaacaaaatg aaatggaagt gatcattcaa gaattatgga atgaattagg caatgtcagc
     7021 tctgctgcaa aaacactgtt tcttcatcgt aatactctaa aatatcgaat cgaaaaattt
     7081 caagaacagt ctggtttcaa tctaaaaaaa gccaacgatt tactgttttg ctatctttta
     7141 ttgcttcatg aacataatta aagatagatt aaaggggttg tgacaataat tttgtcacaa
     7201 ccccttattt cgaatgaata gtgttcaaaa gctagtttct cttacatcat tttttcaaca
     7261 aaatgcatta gccggtcttt tacatcttcg gttgaatctt tgattgaatc accataaaca
     7321 gagattttct tttttcctga tttgattttt gctaacattc ccatcaaaga atccaagtca
     7381 ctatctgaaa gaccatctac gatttctagt aatttttcat ttccatcaaa tttgtcatag
     7441 acgaattttt ttactttcgt ccgagtagtc atatgatgga tcttttccat tacttttccc
     7501 gatacaacga ctgctgtcgc tacactggca gcggctgcta cgcttaatcc gattgttact
     7561 tttgttgatg ttttcataag tatcagctcc tttttatcta tctccatcat agcatagaca
     7621 aaaaaataaa cgaactaatc cactcagtga aatctcaatc ctttagggaa aaagttcttt
     7681 actgttcctt ttacttgttt cccaaatccg acaggtatct tatctaatac tagcaaaacc
     7741 catccttgat tcccatcacg ttgaaatgtt tctcctgctg tgtaagattg ccattccttt
     7801 tgagtgatcg gcaagcaagg tatattctct atcttttttg tagcaagcgc taatgcatag
     7861 ctaggttcaa atcgattctt tttgaaatct cctaaatgca aacctgtacg tacgactttt
     7921 aaaccatcga gagaaggggc taactcagga acttcccaaa gatggtcgtt gaacactaaa
     7981 agtcttccag tagcttcata atgaaaatca tttgaaaact ccgtccagag tttttcctgc
     8041 tcttttgtca tttgcacttt actttttttt cgtgtcttct tttctttatg catctgattt
     8101 tgtccatgaa aagtcagctt tgcaacaaaa tgtccttcac cctgatcttt atgaggccat
     8161 atacgtattg ttttttccaa accagctacg cttccccatt cagaacgtcc tgaactaacg
     8221 gattgagtca aaggaatctc ctcaatcgtt actggataat tttctacaag ccagctaatg
     8281 atctcttcat tttcttctgg tgcaaacgta caagtcgaat aaatcagttg tcctttattt
     8341 tttagcattt ttattgctga agacaaaatc tcttgctgac gtttttgaca gtatagcgga
     8401 gattcttctg tccactcttt tattgcattt ggatcttttc ggaacattcc ttctcctgaa
     8461 caaggagcat caaccacgat ccgatcaaaa aagcccgaaa aatgagggac aagttctgcg
     8521 ggtgcatgat ttgtcactat tgcgttcgaa actccccatc gttctatatt ttctgataaa
     8581 atcttcgcac gtttcggaaa gatctcattc gtcactaata accctttccc cttcatttga
     8641 gcagctaatt gggttgattt accaccggga gccgcacaca aatccaaaac tttttcaccg
     8701 ggttttgctg cagcagctgt tccaacgatc attgcacttg gttcttggct atattcatac
     8761 ccagcttgat ggaggaaaga ctttccattg acagtgccaa gaaatccctc attgctgtag
     8821 ggagcgggtt gtaattcttc gctatggtaa gtttggacca tgtccaatcc tgccggtttt
     8881 agtggattcc accgaaatcc ttttttcacg cttccttgtt caagcgcaga aaaaaaatcg
     8941 gatgcttctt cgcctaaaag aagacgatat tttttgataa attgctgtgg taacgttgtc
     9001 gcttcctcct tcattccaat gtttcgttag acattttaca atctttttta cgaaaaataa
     9061 aggtggctga tctacttttt catgttgctg cctaaggtga ctgttccttt aagatatttt
     9121 ccaagtattc atccgtcacc tcgtttttat cccaaacagc gttcatcatt tcaagaaaat
     9181 cttgagaaga atcatctgag cgcaaacttc ccaatgcatt aagccatacc aattcaagcg
     9241 acttttcttc tttgatcttc gtgtgacctt tgacatatga gaaaaatggc cgcttaaata
     9301 gcgaatccat gtctaaatca gattttgcaa tgatttcacg aatactttca tggatagaaa
     9361 aaaaatcttt caataagtag acaatgctta aaacatcatc ggaactgcat tcagctaagt
     9421 agttttcaaa ataaacagtg atttcttcta atatcttctc ttttaacccg ctgattgatt
     9481 tgaaatgtgt ataaatcggg tatgtagaac aaccgcagaa ctctgctaac tctcttgcag
     9541 taattgactt cattccatat tcttccacgt ataccatact tttgaacagc aaatattctt
     9601 tactataatt tgttactctc cccatcattc ttacctccgt ctcttttcat ctacccataa
     9661 ataaataaca taaataattc taaaaatatt attgataatt atcaaaacat atttagttat
     9721 atccattaaa aatcaatttt tccgccttaa aaacaagaat atcttgacaa aataccctag
     9781 gaaataaaca atagaataaa caaggtaaca aaaaaattaa ataacgttat ataaaaaaga
     9841 aggcgacact ctgtgagaat aacacagact gaaatgactt tccactcaca gtttttgtct
     9901 aactatatac aaaaacagaa taaaaaggag gtatttatgc taattgaagc aagaaaaaaa
     9961 gagttacttg ttctacaaat ggtcattcaa aaaaataatt gttctttaca agaattatcc
    10021 aatgacttac atattccaaa acggacaatc aaagaactga tccgaaaaat aaatgtatca
    10081 ctcaagcaat ttttattgat tgatgaattt atttattcta atcataaagg agagatccaa
    10141 accaaagaaa ccgatcaaac taaaaagtta gctgtttttt ctaagttaaa attatgctac
    10201 ctaaaagaat ccaatcgttt taactatttg atgttactaa tcaattatcc acaaactgct
    10261 gtaccaaaaa aatatttact tgaacaactt tatatatcgc cctcctatct cgaaaaactg
    10321 acaaaacagc tcaatcattc cttaataaaa ttccatttac ggatcctatc tgtaaaaaat
    10381 tgctgtactc ttgaaggaaa tgagttatct atccgtctct atctttactt ttttctttca
    10441 gatacatttg gaggtaacga ttggccattt tcctcacttg aattaaatgc actaaaaatg
    10501 aacagtacag atgagcaaat agaaaaaatt tcaaaacaag aaaaaaatat ctacttgctg
    10561 ttaactttat tcatattacg aaacaaacaa caggcatatt ttccaaaaac ttcttctgaa
    10621 atcactgaat tgatggactt attgcagcat acacatgatt attcagaata ctttacttct
    10681 ttttcagtga gtcgcccttg tgaagagaca gaaacagaga gagcctactt taattatttt
    10741 ttctattgtt tttttccaaa tcaaatctct tttcgacaaa aacaggagat tggtttttta
    10801 ttttccacaa gcaaaaacct tatttgtcga caagtcggtc aattgatgac ttacttaact
    10861 caacagtttc ctctcaacca tttagaaaat aaaataccaa tttattttta ttttcttgtg
    10921 ttggcagttg tttttttcga actgttgggt gaatccagca gtagtttttc tacactttgc
    10981 tttccagaag ccacgtccaa tcattctagt tcttttatac aggaaaagaa attaagagaa
    11041 aaaatcgata caattttttc aaaaaatggg gaaagaaacc aaatcagtca ataccttagt
    11101 caattgatcc aacacttact acaaacagaa acgaaagagc agttactcat ccatttgcag
    11161 ataaccaaac agtttacagg aaattatcat cttcaaagcc atttgcagca gttatttcgc
    11221 aaagatgctg ttaaaattac cgcatattca gaacatgctg atttgatcat tacagatcag
    11281 catgagaaaa tttcagatga aacggagact ttctatctgg atacaacgca caatacagtg
    11341 ttatttggca agttaataaa agcggttcat gaactgtata tgaaaaaagg ttatgagaac
    11401 aaaacaaaga ggatgtgaca aaattcttgt cacatcctct tattccaaat aaatggtatt
    11461 caatcagcta actctcggta ttagctcaga tcaaagcgct gatttcacaa cttctttatt
    11521 ttaatctctt cggttgccgc cgaacaataa gatcaagcgc aacagctgca ggaatgtcga
    11581 aagcgctgct gcaacataag tcagtgctgc tgcaaataat acgtgtcttg ccatcggtac
    11641 ttcttcttcc gtcagtagtc cgccttcact caaaatttgg attgctcgcc gagacgcgtt
    11701 aaattcgact ggtaatgtca ccaattggaa aagtaatgct aaagaaaaag cgaaaatccc
    11761 gatattgatt aacgtagagt tccagctaag caatacacct accataatca aggggaacga
    11821 aatcatcgaa ccaaagttag ctgctggaac aagtgctgca cgaatcttca atgggacata
    11881 acccgaagca tcttgtaccg catgtccgca ttcatgagct gctacaccta tcgcagcaac
    11941 tgaagtagac tgtgcagttg cttgagacaa actcaacatc ttattacctg aattgtagtt
    12001 atctgtgaga tctccggcaa tttgttgaac accgacatta tttatctgtt gactttgtaa
    12061 tatatattgt gctgcttgtg taccagtcac attgtttttg cttctcactt gatcgtattt
    12121 tcggaaagta ctattgacgt acgctgacgc aattccggaa ataactaatc caagaatgac
    12181 caaaagaaat gtcggatcta aaaaaccata cattccataa ccatacattt tcgtttcact
    12241 ccttttcgtt tactttattt tatcattagt agtaggaaaa gaatgtgaaa agaccttgaa
    12301 tattctttaa ttctttttca caaattccga tttcagtttc atcggtccaa atccttctac
    12361 cttgcaatcg atattatgat cgccttctac taaacggatg ttcttgactt ttgttccttg
    12421 tttaatggca cctgacgcac cttttacttt caagtcttta atcactgtca cgctatcgcc
    12481 ctctaacaga cggtttccat ttgcatctaa taccactaat ccgtcttcta tgacagtttc
    12541 ttgttcttct ttgttccatt cgttcccgca ttctgggcaa atcaacaagc ctcgatcttc
    12601 atatgtgtac tctgagccac attctgggca atttggtaat gtcatcttct ttctccttta
    12661 aaatctttag tgagcactat tgtaacggaa aaagaagatc ttgaaaagat acatttgtga
    12721 tttttactac aaaaggcacg ttttcgaacg aagtatcatt ctgtttttct gctcttatac
    12781 gattggcata tatcttggat ctctttatag atttcctcta cttctgctaa atcttttgca
    12841 ttcgcaccac ttgctaatgg atggcctcct ccatgatggc gtttagccaa ttcattgatg
    12901 atcggcccct tagaacgtaa acgtacgcgg taataccctg aaggctgctg aacaaaaatc
    12961 ccccaagcca gcacttcgtc aatcactcca ggaagtgaaa cgatcgaagc tgtctctgaa
    13021 tcatcgattc catatttatc aagaatttct tgcggaagga ttattcttcc tgcaccattt
    13081 tcatccacct ggatattttg ataaagataa ccggaaagtt tagcgacttt catcggcatt
    13141 tgttcaatct ctctgttcaa agcacttgca tcaaatggat aatttctcaa tatcgaagca
    13201 atctctaatg tacgggacgt cgtggaggga tacaaaaagc gccctgtatc tccgacgatt
    13261 cctgcataaa gtaaccgtgc agccttaacg ttcatcttta aagattcagg aaacatcaaa
    13321 gcaaattctg caatcatctc actacagcta cttgcttttg tatttaccca cacaagatct
    13381 ccataagggt catcattggg atgatggtcg attttgatca gtttttctgc caactgatat
    13441 ctttgatcac tgattctggg tgaattagct gtatcagtca cgatgactag cgctccttgg
    13501 tagaagacat cttcaacttc ttgcatttct gctaaaaagc gaagcccttc aatcgtttca
    13561 cctacttgac gtatttcttt ttctgggaaa ctttcccgta atagttcggc taatcctact
    13621 tgtgatccta atgcatcagg atcagggcgc aaatgcctgt ggataatgat tttatcgtat
    13681 ttttttattg tatctactat ttcttgctgt actgtcattt cactcctgct ttctaagaac
    13741 gttccattac ttgacaaaca acgattgctt tggaaacgat ggtgttttca ataaacactt
    13801 cgatatccag tttagcggaa cgtctgccga tttccaatac acgtggacga atgtctaatt
    13861 cgctttccaa ttggatcagc cgcaaataat gtaggttcac ttgttcaatc aagatatttc
    13921 gtttttggtt catcaccatt gttttttgtg cgacatcaga aatgatttcg ctaagtacgc
    13981 caaaagaaat ggttccaacg ccattgacca tttgtggtgc tactacgaat ttgaacttag
    14041 ggttttccaa acgatttcct tcacggtcag tatcaatcgt atggatattt ccagatatct
    14101 gatccgaaat cgtatctgca atctgcggtt gtcgctggac aagctgcatc gctttcatta
    14161 catcttgccg ggtaatcaag ccttccaatg tcaagtcatc ggaaacgacc ggcatgactt
    14221 ctagcccatc ccagatcatt tgatggctaa cagaggcaat actcattgtt ttctttacac
    14281 tgattggttc tttcgtcatc acccgatcga tgatctggtt tggcgatttc cctaaaacat
    14341 cttttgccgt aacaatcccc atcaaacgat gatggcggtt gacgactgga aaacgcgaat
    14401 gctgcgtttc ttctgacaaa cgctgataat cagaaatcgt atctgtctgc tgcaaataat
    14461 gagtcttttc agctggcata tagatatcac tgacaagcat gatatctttt ttgatcaatt
    14521 ggtcgcttaa cgctcggttg atcatggttg cgactgtaaa tgtatcataa gaggtgcgta
    14581 agatcggcat ttcaagatca tcagctagct ttgcaatctc agcagtcgta ttgaatcctc
    14641 ctgtgatcaa tactgcggcg ccatcttcca atgctaattt ttggacttcc gcccggttgc
    14701 cgacgatcat tagtgatcct ggcgtaatat agcgttccat ggcatgttta gtcatcgcgc
    14761 cgatgacgaa tttattcaag accttgtcta atcctgccgc cccgcctaaa acgtcccctt
    14821 caatgatcct gacgacctcg ccaaatgtca aacgttcaat atgttttttt aatttgcgtt
    14881 cgatacggat ggtccctact cgttgaattg ttgaaactag tccgacattt tctgcatctt
    14941 tgattgcacg gtacgctgtt ccttcactga cattcaattc ttttgcgatg cttcttacag
    15001 aaattcgatt gccaacaggt aaactttcaa tatattctaa aatcaaatca tgttttgtcg
    15061 ccattttctg cctacacttc cagcgtttcc gagacgctca ttatttttcc ttcactatct
    15121 tccagtaact ctacaaaaga ttcgggatct tgttcaatga cagggaaagt attgtaatgg
    15181 attggaacta ctttcttggc acgaattgtt tgcgcagcct ttgctgcatc ttctggcccc
    15241 atcgtatagt tatcgccaat cggcaagaaa gcgacatcaa tatcgaattc ttctgcaagc
    15301 aatcctagat cactgaaata agcagtatcc cctgcatgat aaatcgtttt tccttctgct
    15361 tgaataataa ttccgctagg ctcgcccata tactgaacga taccgtctac ttcatagctt
    15421 gaactatgct gtgcatgtac gaattttacc acgccgaatg gaaacgcatg ttttccaccg
    15481 atattcatac cgaatgaatc tactcctctg ctgttcgcat aatcagcaat ctcaacaata
    15541 ctgataattg tggcttgatt ttcttttgca ataggaatca tatctcctat gtggtcacta
    15601 tgaccatgag taatcagcaa ccaatctgtc tttacttctt ctgcagttaa gtctgtcaat
    15661 ggatttcctg taataaacgg gtcaatcatc acgcgttggc cattttccat ttcaattgtt
    15721 aaacaggaat gtccatgata cgtaattttc atattttaca cctcgcgttt tctctgtatc
    15781 ttttttatta aaaacgattt catcacttgc acatcaatga aaaaatatag ctgctaaata
    15841 tattttcatt ggattgatag tacagtatgt acaaagcaat tgtaacagat aatacaggat
    15901 gcaccaagta ccaagcagat ataatctcaa gtttgaggtc tctgctctgc ttagcttctc
    15961 ttctcgtccc ttaactaatt aaatcagcgt aaataggatg gacgatcttt tctaaatcgg
    16021 ctacttttat ccgaaggctt ctcccgattt caccgcttga cacaattact tcttcttttt
    16081 cttttaaaga actgtctgct aaaaaacaat aatcaggatg tgcgagtttt attccaatag
    16141 gggtgtttgc tccgtgggga tatcctgtat gcattaatac aaaatccatt ccaggaaaac
    16201 caactttacg atctttcgtc acttgtctcg tttttttgta atctaagtga tcgttcaaag
    16261 gaatcaatgc gatgatcacc ccagttttgt ttcctttcac tacgagagtt ttacatatca
    16321 aagctggatc aatccctctt ttttgtagtt cttctgtgaa agattcttct accacatgac
    16381 taaaatcaag tggttgatag ctgatctttt gttcttctaa ataacgttcg acttttgttt
    16441 gactcatcat tgattcactc cctttattct atcgtttatt ataaagcgag ggatgctgta
    16501 ttcaaaaatt atttgttttt cgcaaaaaaa gagcaagacg agcactctat agagaggttc
    16561 atcttactct ttttgtttat tttttatttc gacgttgagt agcttccata atgactggca
    16621 agatcactgg gcggcgtttt gtttgttcaa ataagtaacg gcctaattga tctcggatgt
    16681 cttgctttaa tttgctccac tcaaaatcat tgctttctaa atgtttctca acgattgttt
    16741 caatcatatt gctgctttct ttcatcagat cacggctagc ttttacgtaa acgaatcccc
    16801 gtgaagtaat ttgaggtttt gaaatgattt tcttttctcg ccgactgata gtgacaaccg
    16861 ctacgaaaat cccgtcttct gacaagattt ttcgatcacg taaaacaatg tttccgatat
    16921 cacctatgcc taatccatca atcattacat tttctgcact tgtagttcct gcaacactca
    16981 tacgcttgtt cttatattcc agcacgtctc cgcgtccagt aatatagata tttttgtatg
    17041 gcatccctac tgcatgagcc aaatctgcat gagcagctaa ttcacgatac tctccttgaa
    17101 ctggcacaaa atatgttggt ttcatcaaat tgatcattaa ttgcaagtca ttaggattgg
    17161 catggccaga aacgcgcata ttctcagaga tcaacttcac tgttccacca gctcgataaa
    17221 tgatatcttc cgttttcgcc acgatggttt ccatcgcgat gcttggcgta gtagtgatat
    17281 aaaccaaatc tccttcttca atcttgacat tacggtgtgt accgtttgcc attttttgca
    17341 gagacttgat gggttcaccc attcggccag tttctaaaat gatcagttct tctggatcat
    17401 agtttttcat gtctttcaac gtaacaagca gatcttcact tggtaattga agtttttcta
    17461 aacgcatcgc tgtgcgaata attcgttcga aatcttgacc agtcaagaca acttttcgtt
    17521 gtgctttttc tgctgcatcc aatacttgtt gcactcgttg caaattactt gctacacaag
    17581 cgacgatgat acgcccttcc caatatttga tcgtatcaaa tacttcatct gctatttggg
    17641 cttcagaagc tacaggctga ggattttctg catttgccga ttcacttagt aaggctaaga
    17701 ctccttcttt gccgatttcc gccaatcgtg cataatctgt ttgatacatt gggatagccg
    17761 tttggtcaaa tttaaaatct cccgtataaa cgatactacc ttcttttgtt ttcagattga
    17821 tccccactga atctggtatc gtatgagtgg tacggaaaaa gctcactact gtttcaccaa
    17881 agtctatttc tgtatgctca tctaccacat ggaaatcctt aaatcctttg gctgcttcat
    17941 tacgactgac attcaatttt gctaactcga tcgtcaactc tgtcccgaat actggtacag
    18001 aaatttttga caacaagtaa ggaagtgccc cgatcgcatc tgcatgtcca tgtgttaaaa
    18061 agacaccagc tacacgatca atgttttctt ctaaatacgt aaaatcaggg attacgacgt
    18121 cgatccccaa caactcattt tcaggatatt ttagcccaca atctaaaata aaaatatcct
    18181 cgcccacttc tgcgacatac atgttttttc cattttcacg aacgccgcct aatgggataa
    18241 ttttaatggt actcacaaac ttcacctctt cttatgacat ccaagtttaa agatgtcgat
    18301 tttcttcttt atctaaatat atgagccatt ccaatgaagc atatgcaaaa tcactatttc
    18361 tcaacttatg gagaatcagc aggaaaatta ccagcacatc cgcgttctga cagttggatg
    18421 ggcattttat tttggatata cttcattaac aaaatggatc ttttgcgaaa cgctatagcc
    18481 agaatactta tataagtatt cagctgttcc ccattattat acaacaaata aactaaatcg
    18541 ctagtatcag caattgttag aacaactatg cacgtaaaaa tccctctgta gcatctagga
    18601 tttcttttgc tattcctctt tcatttcttc ttcgtcggtt tgaaacatac ttttttcatt
    18661 ttaccacatt ttttgcaata actatagtga ctttttatat atacagaacc tcatgttgat
    18721 ggtgtgcaaa cagcataaga tttaagctag ctttaagata ggttgtctat tatcaaatgc
    18781 atctactagg agggatgcaa aatatgaatt ttatgaaacg tgcatggaaa agtacaaaag
    18841 taaaatgggg acgttcattg ttattgtttg ccgtgttcac agccattctt atttttgtgc
    18901 tagctggcct cacgattcga agcgctgcag aagaagcagc gaatcaagca caaaaagaag
    18961 ttggagcaac agtgacttta agtgccaatc gagaagcttc atttaaaaaa caggaacaaa
    19021 cttcttcaag cggttctacc actgaagaac gtccagatcc aggcagtttt tctcttacac
    19081 cagtttcctt aacggacgcg gaaaaaatag ctgaattaga taatgtaaag agttattcct
    19141 ttgaaagttc cgcctcagct atggcaaaag atggaataac tgccatcact agttctgatt
    19201 caagtgaaga cagttcagaa actactgatg caggcggtga acctgctgga ggaatgggcg
    19261 ggaatccgca aatgactcaa gcagactttc aaatcagtgg tgtgtcagca actgcacaaa
    19321 atagtaattt ttctgatgga acagcaaaaa tcacggatgg tgaaggaata gatgacagcg
    19381 acaaaggcac aaacaatgta gtcattgatt ctactctagc agaaacaaat gacctggcag
    19441 tcggagatac tttcacaatc acgagtactg aagatgaaga taccacttat gaaatgacga
    19501 tcaaaggaat ttatgaatcc agcgaaacaa gcggcagtat gggtatgaaa ttcaacttca
    19561 tgaatccgtc gaatacactt tacacttctt acacttttgc aaatgaacta aatgggacat
    19621 ctgacgataa cacgatagat tctgctattt acactctatc tgatccagat aaaatggatg
    19681 agtttctcaa agaagctgag aagctgatcg acacagatac atttagctta caatcaaatg
    19741 attccatgta tcagtcaatg ttggaacctt taaacaacgt ggcaagtttt tctaaaaatg
    19801 ttgttttact agtggctgta gccggtatta tcatacttac tctgatcatt atgattacca
    19861 ttcgggagcg tcggcatgag ttaggcgtct tgctatcttt aggagaatcc agaagtaaaa
    19921 tcattctcca attgtttacc gaagtggcta tttgtatgat tcttgcatta ggagttgctt
    19981 cgcttagcgg aaacgtcgtc gcgaatgccg tgggacagca gctacttgac caacagacag
    20041 aaaccacgac acaaaaccag caagctcctg gcggtggaca aatgccaggt aacagacaag
    20101 aacaaggcgg tcaacgcgat ggtcaacaag gaaccacgaa taatccattt gctgtttctg
    20161 atcaagtcag cgaattggaa atcaatgtca aacctgcaca attgggacta ttagccggag
    20221 tagcatttgg aatcagtctg ttttctgtct ttttagcttc tatagggata ttaagattaa
    20281 acccaagaaa aatcctatta aactaaagga ggaatttgat gttacggaca gaacaattgg
    20341 gattttggta tcaagatccg caagatgcgc tttataaaga tgtagaactg aatttcgaag
    20401 ctggaaaaat gtacgctatt ttaggagcaa gtggttctgg aaaaacgact tttctttcgc
    20461 ttatttctgg actagatgca ccaaaagaag gaaaggtata ctatcaagat cgttcactga
    20521 acaaaatcgg gttaagaagt tatcgtaaaa atgatgtctc gattattttc caagcttaca
    20581 acttgcttcc ttatttatcg gctctagaca acgtcatagc agcaatggaa atcactaaga
    20641 ccaagcaaga gaattatcga caagttgctt tagatcgact ggctcgtgta ggaattgatg
    20701 aaatattagc aaaaaaacag gtgaccaaac tttcgggagg tcagcagcag cgagtcgcta
    20761 tcgttcgtgc tatctgctgt gaacatcaac taatcgtagc ggatgagcct actggaaatc
    20821 tagatgaaac aacttcacaa gatatcgtca aacttttcca agaaatcgcc catgaacaaa
    20881 atcgctgtat tatcatcgtg actcatgaga ttgaagtagc aaaaagctgt gatgaagtct
    20941 ttgaactaaa aaataaaaaa tttcaaaaaa tcgaagttta aaaaacagga taatgatcaa
    21001 ataaaaaatc cgaaccatat ctgtctcgca gatatggttc ggatttttta tttgcttgat
    21061 tcaattagta ataagtggtt tttatttttt ttcgtctttt cgagaaaact tgtctttgac
    21121 ttcgtcgcct aaatttcgag ctttttcttt gatgtcagca cctagtgatt gtgctttccc
    21181 ttctgtttct ttgctcttgt cgtctgttgc tttgccgtat gcttcttttc cttcaccgac
    21241 tactttatct ttcatatctt tagaacgtcc ttttaaatct gccattgtgc ttcctcctct
    21301 tagtttgttt attgatctac cttcagggta acatcaacaa cagatacaga caaacagaac
    21361 gctcgttttc taaaaaagat agttagagct gttgattaaa aacttttttc gaaagtcccc
    21421 catactttga cttctttttc ttggaccatt atttctcctt tagcgataac tgtatcaata
    21481 tcaagcgttt ctttatccaa gatacacaga tctgcatcag caccaatttc gatttttcct
    21541 tttttatcca atttcaatat acgtgctgga ttactggtta tagctcgtaa ggcgatttcc
    21601 aaagggatac tttctttttg cacagcttct ttgatcccta ctagcaatgc cttggcactt
    21661 cctactccta accctaggaa atgattgttt tcatcaaaat aaggcaagct tccttgtcca
    21721 tctgaggtca tcgtgaaatt atctaaagaa acatcttcct cgatcaatcg tttcagtgct
    21781 ttgctgaagc gaacttcacc atctgtcttc tcccaaaaat caggatcttc gctagcagtg
    21841 aagtcaatcg tgccaccacg tttggcaaat gccacgcaag cttcaaataa ttctggtgtg
    21901 cgatttgcat gagtaggcaa aaattgtgtg atcggaattt ctgtttcttc tacgattcgt
    21961 gtcaatagct ctagctttct ttttcctccg cctaagtgga cattgatgat cccagctttt
    22021 ccggataaca tgcctcctac acgagcatct gctactgcac gagcgaactc ttcaaaactt
    22081 ggctgagaag aacggtgatc ggatactgcg atttctccga ttccgataat tttatcaatt
    22141 gtcaaaaagt ctttgatgat agaatctgtt actgttttta ccggcaatcg gtacgaacct
    22201 tcgtatacat aagtggagat tccttctgct tccagacctt tcgctttgct gatcaacgca
    22261 gtcatatctc taccttctcc gtctgttccc aaacaaccga caactgtcgt tacaccagct
    22321 gtagtcaatt ggctcaatgt gacttctggc gttcgatttt gataaccgcc ttctcctcct
    22381 ccacctaaaa tatggaaatg acagtcaatg aaacccgggg ttagtacttt tccctcacct
    22441 gaaagttctt ctacttccac tccttcgtag ccgccttcta gctgttcttc tacagccaaa
    22501 atcttcccac cggcaatcag tacatccatt tttcctaagt aatctggtgc aaacacttca
    22561 atttgtcgaa tgattttcat acatttttcc tctttcttta agtataactg atgataggat
    22621 cttaaaaaat aatccaaacg ataggatctt tactcctttg attttaccgt aaaatgacgg
    22681 ttcttggagt ccttatctac tgtttggatt acttttttat ttacaggtct ccagtactac
    22741 tgcagaccta ttgcaatggc aatcatgatg aaaatagttc ctaaaacaaa caggaatcct
    22801 tgcatcttga tttggaatct tgcccatttt gcccattcga tccgtgcaac acctagcaca
    22861 ccaatcaagc tggctgatac gggtgtaaaa gcgtccataa aacctgaacc aagctgataa
    22921 gcaagaactg ctacttgtct ggatacacct actaaatctg ccagtggagc catgattggc
    22981 atagtcaaag ctgcttgtcc tgaatttgat gtaacaacca agttgaacaa actttggaag
    23041 atgtacatcg cccaagcacc aatgacagct ggaacaccgg tcaacgccgt cccgatccca
    23101 tgcaaaatcg tattcaaagc tgaaggaaca gatgcatcag atcctcccaa gacaagaaga
    23161 atccctttgg ccatacctac tacgattgct gtaccagcta aatcagctgc accagattgg
    23221 aaagaagaag cgatgtcatt gactttcatt ccatctaatt tgaaaagaac agcaatgatt
    23281 ccagcaacta atcccatcac aaagaattga gaagcgattt ctggaatgta atagcctttt
    23341 tgagtcacgc cccaaacgat ccagacaagg acaactaaca tctctaataa gatcaattta
    23401 tgcccaagca tgaatttttt attttcatca gatgtctttt tgatatgaga acggaaataa
    23461 tcatctgatt tgtaagtcaa cgaactttct ggttttttac ggattttttc tgcatatatc
    23521 atcatataac cagcggctaa tgcagtaaca actacccaca taatcaatcg gaatgtcgca
    23581 ccagacaaca cggggattcc agcaatccct tgagccaccg ctacgctaaa cgggctcatc
    23641 caagaggtcg catttccgac ttgagatgcg acataagtca cggttactgc tacgatcgag
    23701 tcatatccta acgcaatgac aaatggaacc atcaccattg agaatggaat tacctcttct
    23761 gccatcccga atgtagcgcc accgaatgaa aaagcaaaga ataatagcgg taaagctaaa
    23821 cgctccagtc ccttagtttt actgataaac gcatagatac ctgcgtcgat cgctccggta
    23881 cgcataataa taccaaaagc acctccaaca acaaggatca atgcagcgat ccctacagca
    23941 gatccatact tatctccaga tactagtcct tcaaaaacaa aatttaagaa accaaagccg
    24001 ccaaaatcat ctgttcccca tattttggct gttttatgca attttttaga agtatcatag
    24061 atattttcgc cgtactgatc gtaaagcaca tcatctgtca aggagatttc atctagtttt
    24121 tcctgcgtaa gatttttttc tccgtcagca atgacttttt ccaatccttt ttccggaaca
    24181 tccagttttt cacgttctgc tggatgatct tgcagttctt ctaattgatc aaacacatac
    24241 gacttatcca gctcgtaagc ataacggaag gaatcttgac gtaaaacagt acgagtactt
    24301 gtttcgccat ttgcatcttt gtattcaata tcttgcgtgc tgaactttcc tgctggaacg
    24361 acaaaagtca gtatccatgc aaagatgact acaccaaaaa taatgacata cgtatggggt
    24421 gtcgataatt tagtgaagtc gcgtttcggt tttcctgaag aatttgtttt cttcaaattt
    24481 atttcttcct ttcttttttc agtaattttg atgaataaaa aatggataat caaatgaatt
    24541 atacagtaaa aatgacattt ccacatgaat aatttattag aaaatcactt ttttctattt
    24601 tgtttttttt ctcctatgta tgattatttt tttctctttc catttatatt aagtatttta
    24661 tttctctgtt tttccttaaa attctttttt tatttttaga ttagagaaaa tctcgtcctg
    24721 tttttttcat tttacaatca ttgaaaaatt gaatttcatt gcaaaaaaaa taataaacac
    24781 ttataaatat ccattatcta tccttcaatt tttgtgtatt ttatttctat tagaaaaagg
    24841 tatcctgttg gacaattttg ttatatcagg taaacttcat tgcaataatg ataacaaatg
    24901 tactataatt actttgtaaa gagttttggg gaagactctt tcatcaacgt gtattaagag
    24961 acaagaaaga atccatatgg attctttctt gtctcttttt ccactacttt ttatttttct
    25021 gacactacat attcttataa ctcatttctc ataactgtga aacaacttat aaaaataaca
    25081 aactttaaac aaaacaagct taaaatcaaa gatgatccat cttaaaataa ctaaaacaaa
    25141 aaaagtagtc gttgttaatc ctcattaata atcgttttct ttttttcaaa cgctccattt
    25201 ttatgtggaa cattattttt ttaaggaact ttgtcaacat gtggataact attttccact
    25261 tgtgtcctgg actagctgtt ttgctgtaaa atacaaaact tgctgcagca aaaagatcgt
    25321 tgcaagagag gctgttccgc agatcgctgg atctagattt ggcaaagtca agactgcatc
    25381 atgtaaattg gcgtggttgt ccaaaaccaa atcagcaaat tcaaataatc gcaaaccact
    25441 gctatgttgc gatttgatac ttcgtgacaa atcaaatcca gtaacaatga ttaatggatg
    25501 accattttct ttgatccact gagctagttc gatgattgcc gggtttcttc cttcattcga
    25561 aagaagaaga aaaatgtctt ctgatttgac agaaagctga tcaataattg cctgtcctgc
    25621 accttctagc gtttcataga cacctccggc tggattttca atcaatatac ttggtacaag
    25681 atccggggtt tgatcccaaa attcaaatgc tacaccactt agtgtgcggc tagcatatat
    25741 ctgcaatcta ccaccttgat taatttgttt cgcgatccaa gtgccagctt gaagcatcag
    25801 cggctcttct atccttaatt tctcttccaa ttggtgataa tagtcaaaat aacataaact
    25861 catttatctc tcccgcctag ctatacttga catgaataga aacagctgcc taatctaagg
    25921 aagtacataa aaaaacagta gttagacagt aacacatgtg gtctttgctg tttcaaacac
    25981 aaaaaaggca ttgaacgaat acgcccaata ccttgacata gcaaataaaa caacgtgcag
    26041 accatggaaa atatctacat aggggtagaa ttttcaccct agattaggta caataaatta
    26101 ggtcgatgca ctgcattgac tatggcaaaa tgatcggtca gggtgtatgt gtgtgactgg
    26161 tcattccctg attcttagcg ccaactaagg gtcagggagc ctttttttat tcagctgttt
    26221 ctatctgaat ttattgtaag taatctctta tccaagtgca agcaagaaaa tacaaaaaaa
    26281 cattggtatg atttatatat atataaataa cataaaaaaa ggaatggctt atcccgatac
    26341 aacaagcatt cctttaaaaa agattctttt atataagtga aaaaagcttt tttccaccaa
    26401 ttaaataaat ctctcatctc aatagtttat ccattatttt atcttttttt gcgtatacct
    26461 actaaatatt accgtcttct tctcgttctt ctactttgtt cgagagaatc tgtactagaa
    26521 aaagtagttg tatgtctacc ttttctgcct atccgagact ttcttttcat atatgggata
    26581 taaatgatta gatacagtac agcaaaaaat aaagcaaata cgcaagcttc ccaactacct
    26641 aacgccaatt caaccatcaa ggtagcaacc ccaacggatg ctgcatacca gataaaaatc
    26701 agaaacgttt ctttttttct gaccatgcga aacatgataa atagactaat aagcaatagt
    26761 ggcaacacaa atatccaatt gcttccttcc atcagccact tgagtatatc aagcagcgac
    26821 tgtgcaacag cgactaattt tcccatagtg aacacacacc tttttttata attaaaaaat
    26881 tcgccttttt attctactat gaatcttctg gcttggcttt catttctctt atgtaatcat
    26941 tttcttttat acaacttaaa aaaaaattaa accattagca taatattttc tgaatctatt
    27001 cacgaaagtc tttttctatc tttcgttttc cacgactcaa ctgatctaga gtcaaaaaac
    27061 taaaacgaca gttgcgcaaa tgacgcacaa gctgccgctt taataacaaa tagcctttca
    27121 ttctcagcag gccacttatt tccagttaac tttctgttct tagcttttta ctcaactgga
    27181 taatatatgc acttaatgaa gtcccaattt ccgaatgttg aagtccatat tcaatatttg
    27241 tcttcatata tcctaactta tcgcctacgt cgtatctttt tcctttaaac tctctcgcat
    27301 agaccgcctc tgtctggtta agagtctgaa gtgcatccgt tagctgtatc tcgtttcctg
    27361 ctcctggttc ttgagtttct aatatctcaa atattttagg agtcagtaga taacgtccga
    27421 taatggctaa attacttggt gcttttccca tttcaggttt ttctacaaac ccttttactc
    27481 tgcaacgacc cttttcgcta tctgttttag gatcaataat tccgtattta gatgtttcat
    27541 tttctggtac acgcatgacg gcaacagcgg aagcttgtgt ttcttcataa tccatcatca
    27601 attgttgagt caatgggata tcatctttca tcaaatcatc ccccagcatg acgacaaacg
    27661 gttcatttcc tataaatgct tttgcttgaa gcacggcatc ccccagtcct cttggatgag
    27721 attgacggat gaagtgaaga ttgacttgag tcgtttcttc aactaaagcg agtaattctg
    27781 ttttttcctt ttcccgcaaa ttgttttcca attcgatatt tgcatcaaag tgatcttcaa
    27841 tgggtctttt ttcttttccc gttacgatca agatgtcttc gattcccgaa tccaatgctt
    27901 cttccacaat aaactggatc gttggtttat ccacgattgg aagcatttct tttgccatgg
    27961 cttttgttgc cggcaaaaaa cgtgttccta gcccagcggc aggaatgact gcttttttga
    28021 ccttcactt
//
LOCUS       DBBGSZ010000036        25496 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.037, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000036 DBBGSZ010000000
VERSION     DBBGSZ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25496
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.037"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            127..3654
                     /locus_tag="ACIZE5_002060"
     CDS             127..3654
                     /locus_tag="ACIZE5_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HGC6109177.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3651..7373
                     /gene="addA"
                     /locus_tag="ACIZE5_002061"
     CDS             3651..7373
                     /gene="addA"
                     /locus_tag="ACIZE5_002061"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HGC6109178.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7442..7783
                     /locus_tag="ACIZE5_002062"
     CDS             7442..7783
                     /locus_tag="ACIZE5_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HGC6109179.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8092..9135
                     /gene="pheS"
                     /locus_tag="ACIZE5_002063"
     CDS             8092..9135
                     /gene="pheS"
                     /locus_tag="ACIZE5_002063"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HGC6109180.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9140..11560
                     /gene="pheT"
                     /locus_tag="ACIZE5_002064"
     CDS             9140..11560
                     /gene="pheT"
                     /locus_tag="ACIZE5_002064"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HGC6109181.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11730..12740)
                     /gene="trpS"
                     /locus_tag="ACIZE5_002065"
     CDS             complement(11730..12740)
                     /gene="trpS"
                     /locus_tag="ACIZE5_002065"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HGC6109182.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            12994..13731
                     /locus_tag="ACIZE5_002066"
     CDS             12994..13731
                     /locus_tag="ACIZE5_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGC6109183.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13745..14560
                     /locus_tag="ACIZE5_002067"
     CDS             13745..14560
                     /locus_tag="ACIZE5_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGC6109184.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14573..15220
                     /locus_tag="ACIZE5_002068"
     CDS             14573..15220
                     /locus_tag="ACIZE5_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGC6109185.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15236..15892
                     /locus_tag="ACIZE5_002069"
     CDS             15236..15892
                     /locus_tag="ACIZE5_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGC6109186.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16054..16875
                     /gene="racE"
                     /locus_tag="ACIZE5_002070"
     CDS             16054..16875
                     /gene="racE"
                     /locus_tag="ACIZE5_002070"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HGC6109187.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16878..18233
                     /gene="rph"
                     /locus_tag="ACIZE5_002071"
     CDS             16878..18233
                     /gene="rph"
                     /locus_tag="ACIZE5_002071"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HGC6109188.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18234..18752
                     /locus_tag="ACIZE5_002072"
     CDS             18234..18752
                     /locus_tag="ACIZE5_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGC6109189.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18859..19359
                     /gene="cbpB"
                     /locus_tag="ACIZE5_002073"
     CDS             18859..19359
                     /gene="cbpB"
                     /locus_tag="ACIZE5_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HGC6109190.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19639..20559)
                     /locus_tag="ACIZE5_002074"
     CDS             complement(19639..20559)
                     /locus_tag="ACIZE5_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HGC6109191.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20685..21737
                     /locus_tag="ACIZE5_002075"
     CDS             20685..21737
                     /locus_tag="ACIZE5_002075"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HGC6109192.1"
                     /translation="MIKCGENNEGGKYMQIDWNNLGFSYIKTPWRFIAKWKDGQWEEG
                     ELTEDNYLTIHEGSPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLM
                     PMVPEKMFVDAVKQVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVF
                     CTPVGAYFKGGLKPTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCV
                     YLDPATHTKIEEVGAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIE
                     GDIFIDDLDQFAEAGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGI
                     QFGDIEAPEGWIEVVE"
     gene            complement(21847..22602)
                     /gene="fabI"
                     /locus_tag="ACIZE5_002076"
     CDS             complement(21847..22602)
                     /gene="fabI"
                     /locus_tag="ACIZE5_002076"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HGC6109193.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22822..23262
                     /gene="fabZ"
                     /locus_tag="ACIZE5_002077"
     CDS             22822..23262
                     /gene="fabZ"
                     /locus_tag="ACIZE5_002077"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HGC6109194.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23377..24138)
                     /locus_tag="ACIZE5_002078"
     CDS             complement(23377..24138)
                     /locus_tag="ACIZE5_002078"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGC6109195.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24327..25421
                     /locus_tag="ACIZE5_002079"
     CDS             24327..25421
                     /locus_tag="ACIZE5_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HGC6109196.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         8447 a         4424 c         5384 g         7241 t
ORIGIN      
        1 cgtatactta aaaaagtaga aatatcagaa ccttaaaagg atataatttg aagaatatag
       61 aacaaatgtt cagtattttt tgatataata aaggagcacc gtatcatgtg ttgaaggagg
      121 aaaagcatgt ctttacaatt tattcttgga aacgggaaaa aagatcaccg tcaagtcttg
      181 atcgacgaag catccgcttg gctcgaccag gatgcaagta accaagtatt tttccttgtt
      241 cccaactaca gcaaattcga acaggaacaa gaaattttag cggagatgcg aagaagaagc
      301 ggaaaaaaaa ctttcagcac aacaaacgtt caagtattta gtttttatcg tctggcttgg
      361 tatttgctgc aacagacaac tcttcttaca ggaaatgaat tatcagaatc aggatctgca
      421 atgatcttgc gacagatttt agaaaaaaat gaggaagaat taacaatctt tcgcggagaa
      481 atcaataaaa gagggtttat tcgtcaatta caagaactct acagtgaatt gcgtacagga
      541 aatattcaac cagaagacct gatgctttta tttggtgatt cacctaatgc agaagaccag
      601 caacttaaaa tgaaagactt gaagctgatt ttttcagctt atgacagcga attgactcaa
      661 cgtgcactaa caaatgaaga tgcactatct atactagcaa attatatgca gacacaagat
      721 ttcaacaacg tcaaatttat tgtcagtggt ttttctcgaa tcaatggtca agagtatcaa
      781 ttactgcagg caatgatgga aaaggggcaa ttggttgtcg atttattgct ggatcgtcct
      841 tatacagcgg atcttccaga agtacttacg ctctttcatg agactggaaa gctttatttc
      901 cgtctttttc aaagtgcaag agaacggaaa gtccctatat tagtggaccg atttgcacca
      961 gagcagactc gtccgacaga gcttcaactg ctgcaaacaa tgtgggaaga gacatctagc
     1021 caaaagaaag cggcagtaca caaaataggg ggacaagagc atctccattt gtgggaagct
     1081 gaaaatccaa ctgaagaagt ccgacaatta gctgttgaaa tcagacgact agtcagtgaa
     1141 gaaaactacc gttatcgtga tatccaagtg ctgacaaaaa atatgtcttt atatggaaat
     1201 atccttcggc cgatctttca agaaatggca attccttttt atatcgatga agaacaaatg
     1261 atggaaaatc atccgctgat cgaatggatc aacagtctgt tcgctcttga ccgctattct
     1321 tatcggctaa gtgatattat gcgttttttc aaaactgaat tatttctgtc gacggaagca
     1381 gaaaccgaac ttgatgaatg gaaacaagag cgagatgaat tcaggaaaaa actggacatc
     1441 actgaaaatg tagcacttgc ttacaattat caaggaactt attggactcg tgaaaaagac
     1501 tggcagtttg tggcgtatga ttttgaagca gaacagattg aagacgtaca gtatttggaa
     1561 gaacagtcaa atacgattag acgattattt cagaaagctg taccagtatt tttgaaaaaa
     1621 ataaagaaaa gcaaaacagg acaagaggcc gcaaatgttt tttatcaatt tttgatccaa
     1681 agtggcgtac agcaacaatt attgttttgg cgtaatcagg aagtagacag aggaaactta
     1741 gaagcggcaa gaaaccatga gcagacatgg ggagcgctga ttgatctgtt ggatgaatat
     1801 gtagtaattt atggtgaatc ggcttttgac tggtcactgt tccaagaaat cattacaagt
     1861 ggtctagaaa atctaagtta tggtaaaatc cctaccgcaa tcgaccaagt gcgaatcaat
     1921 cgtttggaat tagttcgacc aaatcaagct gccgtcactt ttgcattagg gttgaatgat
     1981 caagtgtttc cagaccgaaa agagacaaaa ggattgttgt ccagtgaaga acgagaagta
     2041 ttaaatcagg ccttgccaga tggacagttt ttattcgacc catcaaagga aagtatctct
     2101 tttgagcctt tccaagccta tcttgttttt ctttccggaa cagatcgatt atatcttagt
     2161 tatgcacaaa gctatgacac agatggttcg ctgaagatgt ctccttattt gcgtagaatc
     2221 acagaatatt tatctgttcc cgtcgagaga aaagagcatt tgacgatcga aagcgaccct
     2281 aattgttatg tagggactta cagaagcgga atcaatacag tcaataggat ttatcgatta
     2341 gctttagatg aaaaaaaacc tgtaccaaag cactggcaaa agctcaaaga attagtactg
     2401 aattcgtcat ggcgaaattt tgctttacag atttttgaaa gtcaggaaca tttaaatgtt
     2461 cctgtttcga tgccagaaaa aatggcggaa gagctttatg gaaaagagat ttatacttca
     2521 atttcacgta tggagaattt ttataattgt gaatacaaat acttcatgca atttggtttg
     2581 aaattgaaag aacgaactgt ttatggtcta actccagcag caactggtga tttttatcat
     2641 gaatcattgg atcgtttctt caagctactg ttttcaaacc aattatcctt agtgaatatg
     2701 tccgatgcgc agcgtagaga ctttactgaa aaagtgctgc aggaagtatt cggagaactt
     2761 cggtttgaga tattggatag ttctgcaaga atgaactata tccgctacca gttaggacag
     2821 acgattcaaa aagtgacatg ggctttgcaa aaacagagca aaaatacagg catgcatcct
     2881 cttcagacag agattctatt tggtcagatt gctggagcaa aaggtatcac aggtctggaa
     2941 ttaccgttga gtaatggtgg aaaactccat gttcgaggga aaatcgatcg aatcgatgta
     3001 gcttctgaac aagaagatac ttggctaagc gtcgttgatt acaaatctag cggacgttca
     3061 ttcgatgtca cagaagctta ttatggcatg gctatgcaat tattgacgta tctggacgta
     3121 gcattgatgg atgcggtacg tttgactgga aaggcggctg ttaaaccagc aggatcatat
     3181 tatttacatg ttcataatcc tgtattgacg gagacagatg atgtagagaa gaatacattg
     3241 aaaaaattta gttatgatgg cgtttttgtc gatgatcccg ctcttttaga agtactagat
     3301 cattcactgg aagcaaaaga acaatcactg atctatccag tgaaaaaaaa tgcgaaagat
     3361 gaataccaaa aaggtagttt cagtaaagac aaatttttca cggaagaaga actgcaacta
     3421 ttcatggcgc ataatcggga aaatatgcgg ttagctggag atgcgattac ttccggagaa
     3481 atcaaactaa atccagctta taaagataaa cagcggattg cctgcgaatt ttgtccattc
     3541 agaagcatct gtacgtttga tgtgatgctg aaagaaaata attaccaccg tctggagaaa
     3601 atagataagg aagaagcact gcgtagaata ttgaaaagga gtgaagaaga gtgaatcaaa
     3661 ttcctttaaa accgcaaaat gaacgattca cagatgatca gtggcaagcg atttttgatc
     3721 aaggagataa tctattagtc tctgcgtctg ccggatcagg taaaactaca gtgcttgttc
     3781 gaagagtgat tgaaaaacta aaaatgggtt ttgatatcga tgaattattg attgtgacat
     3841 ttactgaagc tgccgcaaga gaaatgaaag aaagaattca agaggcatta caagaatccg
     3901 tcaatagcga aagtgaccct gtacgtagac agcattttac taagcagtta gttttattgc
     3961 ccacagcgaa tatctcaacc ttacatgctt tttgcctgac agttattcga cgttattatt
     4021 acttaattga tattgatcca gtctttcgca tgttaacaga tgaaacagaa acgatcttga
     4081 tgaaggagga tgtgtgggac gagctgagag aagcacttta tgcagaaaat gatgaacgat
     4141 ttttccaatt aacaatgaat ttttctaatg atcgttcaga tgacggcttg acgaatctgg
     4201 tgttttctct ttatgagttt gcccgtgcca accctgaccc ccaaaaatgg ctagaacagt
     4261 taagcgataa ttatcgtttg cctgaggggc tagcgaaatc tcgattatat caaaaacaaa
     4321 tccgtccttt agttttggca gatatatacc aatgtgtaca gttatatgaa cagatgactc
     4381 agttagcaca aggtgaagga ttagaaaaaa tgcatgagca agtagctgga gaacaacagc
     4441 agatcaagaa tatctatgaa gcgttctcgc aagatcggtt agaagaagct tatgctggtt
     4501 tggaacaact aactttttca acttttaaga gcagtcggaa agcagaattg aaagaaattt
     4561 ccaatgaagt caagggcatg agggataaag caaaaaaact gattcagcag ataagtaaaa
     4621 gttattttcc tgtttcccca agccaaatgg aagaattaac ggacaaagca ctaccgttag
     4681 tcgaagaaat gacaaaagtc acgcaaagct tcatggacgg tttcagtatg cgtaaacggg
     4741 aaaaaggtgt gctggatttc aatgatctgg aacatttagc gttgcagatt ctcacagaaa
     4801 aaacgaaaga tgtatggctg ccaagtgaag cttcaaaaca ttatcgaaaa aaattcaaag
     4861 aagtaatggt agatgaatat caagacgtga accaattaca agaagccatt ttatactggc
     4921 taagagaacc cgatgataca aaaggaaata tgttcatggt tggggatgtc aaacaatcca
     4981 tctattcttt ccgtttagca gatcctagtt tatttatcgg gaaatacgag aatttctcaa
     5041 agaaagaagg cggacgtcga atcgttttgg ctgagaactt ccgctctaga aaagaagtcc
     5101 tttcttttac gaatcttatt tttgaacaac taatggatcc agcagtgggt caaatcaatt
     5161 atgacgaagc agccaaactg atccaaggat tttcagactt tccagagaat gaacagtttg
     5221 agccggaaat catgatctat gaaaaagaac aggaagaatc agagattgag attccgacgg
     5281 atgatatact ggaagacaaa acagaaggcg aactttttat gacaggacta aaaattcgtc
     5341 aattaattga ttcctccttt atgatttatg ataaaaaatc aaaaaaaagt cgtccgatag
     5401 agtacaaaga cattgttctc ttgacaccta caaagaagaa caacttaacg attttagaga
     5461 ttttcaaaac attggatatt ccattagaga tgaatgatgc tcaaaactat tttcaagcga
     5521 cagaaattcg cacgatgatc tcgctgctac aattaatcga taatccctat caagatattc
     5581 cgcttgcggc tgtattgcgc tcaccgatcg tgggtctgat tgaaccagaa ttagccagca
     5641 ttcgattagc taaccgtgca catacttact atgatgctgt gcttgcttat caagcatcaa
     5701 acgaagatga attagcagct aagctggaac attttggcaa gcaactagag cattggcgag
     5761 aacttgctcg ccgttcttcg atcactgact tgttatggga tatctattat gagacgggat
     5821 atctagagta tgtggtcggt ctgccagcag gggcacagag acaagccaat ctttatgcat
     5881 tggttgatcg tgccaaagct tacgagcaaa gttctttcag aggattatac cagttcgtgc
     5941 gtttcattga aaaaatgcaa gaaaaagata aagacttagc agaaccagtc atttcaatag
     6001 aagataatgc tgttcgcgtt atgacgatcc atgcaagtaa aggcttggaa ttcccagttg
     6061 tatttttgtt agatatgaca aaggagttca acttacaaga cttgcgcaat cggtatgctt
     6121 ttgaagaaaa acttggagca ggaattcgct atatggatcc tgaaacacga gtgttatatg
     6181 atacgttacc gtttcaagcc atcaaattgg caaagcaaaa caaattgttg tcggaagaaa
     6241 tgcgtaaatt gtatgtagga ttgactcggg cagaacaaaa gcttttcatt gtcggttcct
     6301 ataaaaataa agagcaaatg atccaaacgt ggtctgaagc agctgatcat gaggagttag
     6361 tttttgatcc tgcgctacgt ttgaagggca gaagcagctt gatgaattgg attggttacg
     6421 gattgatccg tcatcctgaa atgcagaaat acttagagga agaaatttcg acttctcttc
     6481 ttcaacattc aaatgcacag ttttctattt catggatgaa tcagcaatcg atcattgaac
     6541 aaagacagtt gcttgctgaa aaagaactgg ttaacttaga tcagcagatg aaagaagatg
     6601 aaactttatt agcagattcg ttacaaaaac gtctggcata tgaatatcct tatcaagctt
     6661 cttcacaaac cacaagttat caatctgtat ctgaaatcaa acgattattc gaagatccag
     6721 atgatacaca agaatcacgt ttgactctgg aaagcagtca gaacaaagca gcatcccgtc
     6781 aatttcgtta tacgcaagaa caactagcag aaccaaaatt tttgcaaaaa gatcggcaag
     6841 tgtcagcagc tgctgttgga actgctacgc atgctttgtt acaattactg ccattagaga
     6901 tgccaactac agagagtatc catcaaaaat tacaggaatt ggtaaggaaa cggttagtag
     6961 acgaaaaagt cgcgaaaaaa gtagatgttt cttctattat atggttcttt caaacagaac
     7021 ttggtcaaca gctgattgcc aacaaagaaa acgtaaaacg agaacaacct ttttccatgc
     7081 tgcttcctgc tgacgaagta tttcaagact atccaaatca agaagatgaa ctattaatcc
     7141 acggaatcgt cgatggatac ctagaagaaa aagatcatct caatatctat gattttaaaa
     7201 cagattttat tttacatccg gatgatccag cagaaataga tgcaatcgtc caaaaatatc
     7261 aaggacagct aagactttac caacaagcaa tgtcagaagc tttgaataag ccagtagaaa
     7321 atgttttcct aattttgctt cgagtgaaac aaattataaa cattaacaaa taattataat
     7381 tgagcaaact tgacttatgt tttgtaagga ttatgctata ctctgggaag aggtgagtat
     7441 gatggagcta acacagacag aattcgtttt atgccctaaa tttgaaaaaa cattctctat
     7501 tttaggaaaa aaatggaacg gattgattat cgatgtacta ctcgaaaacg gtccgcaacg
     7561 ctttgttgag cttgcggcaa aaatcccgat ggtcagtgat cgagtattag tcgaacgctt
     7621 gaaggaatta gaaaaagaag gaatagtcac tcgaaacttt gcctgtagcg aaaagagccg
     7681 ttcagaatat ctcttgactg aaaaaggagc agacttgcaa aaagcgatgc gtcaaataca
     7741 agtttggagc gaaaaatgga tcacagagga agaatgcggt tgattttgta aaaaaaatct
     7801 tgtaaactat agtccatacg aataagtaaa gaacgatgac gaaaaagagt agtttggcta
     7861 aaccagttca gggagatctg tcgcagactg aaagcagatc ctgtgtttga aaaatgaagt
     7921 tcactttccg agttcgtctg ataaaatcag accggcaatt gtcgttaacg aagtaagagt
     7981 gcggtgtaag tcatttatcc gcaaattagg atggtaacgc gaagacctcg ttccttaaca
     8041 ggaatgaggt ctttttgttt tgtatttgga atttaaagga ggaacaagca catgtctcta
     8101 caagcacaat tagagagctt gaaagaagca acgctcgtca aaatcacagc ggcacaagat
     8161 ttaaatgaat taaatcaaat acgtgttgaa acgttaggaa aaaaaggacc gatcacagaa
     8221 gtattacgtg ggatgaaaga tctaagtcca gaagagcgac caaaagtcgg aagtttcgca
     8281 aatgagatcc gagatctttt gacagaagag atcgagcgaa aaaaacaagt attagaagaa
     8341 gaagcgttaa atgcagcttt ggcaaaagaa acaatagacg tgacactacc tggtagaaaa
     8401 gtaaaacatg gtacacgtca tatcgtgaca caaatcatgg aagaaattga agatattttt
     8461 gtgggtatgg gctatcagat cgtagaagga tatgaagtag aatctgatca ttacaatttc
     8521 gaacggatga atctgccaaa agatcatcca gcaagggaca tgcaagatac tttctatatt
     8581 tcagacgaga tattgattcg gacacatact tcaccagtcc aagcacggac aatggaaaaa
     8641 catgatttct ctaagggtgc tctacgaatg atctcgccag ggaaagtctt ccgcagagat
     8701 acagatgatg cgacccacag tcatcagttc catcaaattg aagggctagt tgttgataaa
     8761 aacatcacaa tgggcgacct taaaggaaca ttagaagtcg taatgaaaaa aatgtttggg
     8821 gaagatcgtg aaattcgttt gcgtccaagt tatttcccat ttacggaacc atcagtagaa
     8881 gtagatgtca gctgtttcaa atgtggtggt gccggttgta acgtatgtaa atacactgga
     8941 tggatcgaaa ttttaggagc tggcatggta cacccgaatg tgttgaagat gtcaggaatc
     9001 gatccagaag aatattcagg ctttgctttc ggccttggac cagaccgcgt agctatgttg
     9061 cggtatggag tgaatgatat ccgtaatttc tatcaaaatg acttacgttt cttaagtcag
     9121 ttcaaggggg agtaagaaaa tgttagtttc atataaatgg ctcaatcgtt atgtagattt
     9181 atcgaatgta acaccaaaag aattagcgga taagatgtct gtgacaggaa tcgaagtaga
     9241 gggagtaacg gttccagaag aaggcttgaa aaaaatcgtt gtcggtgaag tcaaggaatg
     9301 cgtaccacat ccagattctg atcacctttc tatttgtcaa gtcgatattg gcgaagacga
     9361 actgtctcaa atcgtttgtg gagcgcctaa tgtgaaggtt ggaatcaaag tgattgttgc
     9421 acttcctaac tcacgtatcg ctggtaatgt aaaaatcaaa aaaggaaaaa tgcgtggcca
     9481 agtatcaaat ggcatgattt gctcattaca agaaattggc tattcagata gtgttatacc
     9541 gaaagaatac gctgaaggta tctattatat gccacaagaa gctgtaaatg gcgatccagt
     9601 ttttccttat ttggatatgg atgattcgat tattgaatta tctatcacac cgaatcgtgc
     9661 ggatgcattg tcaatgcgtg gcgtagctta tgaagttggg gcaatttatc gtcagactcc
     9721 tacattcgat gacgaaaagc tggtagaatc ctcacgtcct gctagcgata aaattcaagt
     9781 ggaagttgaa gataaagaag cagttcctgc ttatcaaatc agaatcattg aaggagtaag
     9841 aatccagcca agtcctcaat ggctgcaaaa tcttttgatg aacgaaggca ttcgtccaat
     9901 caacaatgta gtagatgtga cgaactatat tttgctttta ttcggacaac cactacatgc
     9961 atttgactac gacaaattga aatcaaaaga gatctttgtc cgccgtgcaa aagaaaatga
    10021 aacattagta acactagatg gagaatctcg ggaattgaca actgacaatc tcgtcattac
    10081 taacggcaaa gaaccagttg ctttagctgg tgtcatggga gggttagact cagagatcac
    10141 gaatgaaaca acaacagttg cactagaatc tgctttattt gatccaattt cgattcgtcg
    10201 tacagcaaaa caatttaatt tgcgtagtga atcctctgca cgttttgaaa aaggaatcaa
    10261 ccatgcgact gttggagaag ccagtgaggt tgctgcagca atgatcgttt ctcttgcggg
    10321 tggggaagtt ctacaaggcg cggtcaaagg ctcagagatc aaagcagaag acgtatcagt
    10381 gaagatttca cttgaacgca tcaatcaata tttaggaaca tctcttgtcg ttaaagaagt
    10441 aaatgagatt tttgaagcac ttggatttag ctatgaagaa aaggagtatg tttattccgt
    10501 agtagtacca ccaagacgct gggatatcca aatcgaagca gatattatcg aagaagttgc
    10561 tcgtatttat ggatacgacc agttgccatc tacacttccg agtggagaaa cggttgctgg
    10621 aagcttgtca aaagaacaag aaactactcg taaaattcgt acaatctttg aaggaagcgg
    10681 attgagcgaa gcaatcagtt atgcattgac aacagaagaa aaatcaagac agtttgttat
    10741 aaatgaaagt aatattacac gtttggactg gccaatgagc gaagaacgtt ctgtattacg
    10801 aatgaatttg atcagcggac tattagatga tatcagttat aacactgccc gaaaaaatac
    10861 agagattgct ttatatgaaa ttggtcgggt gttcttccaa gaaaatgatc cacgtacaca
    10921 tctgccgcaa gaagtaaaac atgcagcaat cgctatttct ggtatttggg aagaaaaaga
    10981 ttggcagacg aaagctcaaa atgtagactt tttcaccatc aagggtcttt tagaaaactt
    11041 atttgaacaa ctaggcatca ctgaagatgt ccattatcaa acagtgacag aaatgaagga
    11101 aatgcatcct ggaagaactg ctgcgattta ccttggcgaa aaatttattg gttttgtcgg
    11161 tcaagtgcat ccaacgatta caaaaagtta tgatattcca gaaacatatg ttgctgagtt
    11221 tgatttatct gctatagtgg aagctgctca aaaagggatc gttttcgaag cagtgacaaa
    11281 attcccagca gtcagccggg acatcgcttt gcttgtaaaa gaaactgtga caaatcagga
    11341 attaacagaa gttatccgtt ctgctgccgg aagattttta acagatatcc aattatttga
    11401 tgtctatcaa ggagaaaaca ttgaaaaagg acataaatcc atggcgtata gcctgacatt
    11461 cgtcaaccca gaagcaacat tgacagatga agaaatcaat aaagcaatgg aaaaagtcga
    11521 aaaagcgttg gtagaaaacc tagaggcaag tattcgctaa gaaggaaaat atagtaagta
    11581 acgatcaagt agcttttgaa gaccatacat ttgaaaaaaa gatgtgacac aacttcgtca
    11641 catctctttt tttgatttta aaaaaggaat agcacagaga cgagataaaa aaacaggcct
    11701 ttacagcctg cttttttaga gtaaatgaat taatggaagt aattgattcc cattgctgat
    11761 tttacttcag aaagtgtttg tgcagctact ttagcagctt cttcactacc tttacgtaag
    11821 atttccataa cagctgaagg atctttttcc aattcttctc ggcgcgcacg gatcggtgca
    11881 aattcagctt ccaatacatc aatgaggtat cgtttgatct ttacatcacc aagtccgccg
    11941 cggcggtaat gagctttcat ttcttcaatt gcttctttat ctgttccgaa tacatccaag
    12001 taggtgaaga ccatattccc ttctacttgt ccaggatctt gtacatggat gtggtttgga
    12061 tcagtataca tactcatgac ttttttctgt aagacatcgg caggatcgga gatataaata
    12121 ccgtttccta acgatttact cattttgcca tttccatcga ttccaggtaa tctacccatt
    12181 ccttttggtg ggaatacgcc ttttggttcc accaagactt caccatatgt atgattgaag
    12241 ctttgtacga tttcctgtgt ctgctctagc attggttttt gatcctcacc aacaggtaca
    12301 agattcgctt tgaatgcagt gatatctgct gcttgagaaa caggatagat aaagaatcct
    12361 gtaggcacgc tttcaccgaa ttttttttgt tcgatttctg ttttgacagt cggattgcgc
    12421 cgaacgcgtc ctacgctgac taagttcaaa taatacatgg ttaattcagc taattccgga
    12481 atttgtgatt ggataaataa agtagatttt gcaggatcta atcccacggc taaatagtct
    12541 aaagcaactt gcaagacatt tgatgaaacc ttctcaggat ttttagcatt atctgtcagt
    12601 gcttgcatgt cagcaatcat gacaaacagt tggttgtctt catctgcctg catagccact
    12661 cgggttttta gagaaccgac gtaatgccct aaatgcagct tcccagttgg tcgatctccc
    12721 gttaaaataa tatttttcaa aaaagacacc tctttacgat ttgtaagtct gagcacttaa
    12781 tatcttaccg tttttcctga aaagaaacaa cagttcctaa ggaaaaaaca aggaaagagg
    12841 ataaaataac taatagatta gaaatggaag aaatatttat gggagaataa acgttctaag
    12901 aaactttaca aattactaaa ctatcagata taatgtattt tattatacat ctttaaaaga
    12961 aatcttacta aataataatg ggagtgtaat tctatggcaa tgattaaatt tgatcacgtg
    13021 gataaatatt atggcaagtt ccacgcatta aaaaatatca atctcgaatt cgagaaagga
    13081 gaagttgtcg ttgtcattgg tccttctggt tcaggaaaga gcacgatgct tcgctgtatc
    13141 aatggattag agacgatctc ttcaggtaag ctgctgatta atgatactga cttgcatgat
    13201 aaaaagacaa aactgacaga agtccgaaaa aacatcggca tggttttcca acatttcaat
    13261 ttgtacccaa ataaaactgt tctggaaaac atcaaattag caccaatcaa agtgttgaag
    13321 caagaccagg caactgcagt caaaaacgcg gagaaatttt tgaaaactgt caatatgtta
    13381 gataagaaag attcttatcc ttccatgtta tccgggggac aacagcaacg ggtggcaatc
    13441 gccagaggtt tagcgatgaa tcctgagatg ctgctgtttg atgaacctac ttctgctttg
    13501 gatccggaaa tgattggtga tgtattagac gttatgaaaa aattggctca tgacggtatg
    13561 tcaatgattg tcgtgacaca tgaaatgggc tttgccaaag aagtggcgga tcgtgttatc
    13621 ttcatggctg atggagaagt attggaagac agcagaaatg tgagagactt tttcgaaaat
    13681 ccaaatgaag tccgagcaca gcaatttatc agtaaagtta tcaatcattg ataggaggaa
    13741 aaagatgcgc aggttaaaaa aaatacgcct gattttcctt ttaggcattg cttttcttgc
    13801 actagccgga tgtaaaggaa atgggttggc aaatgaagat attttagagc gaagcaaatc
    13861 taccaatgaa atcatctggg gtgtcaagta tgatactcga ttatttggaa tgatggatat
    13921 tgagagcaga actgtacaag gatttgatgt agatattgca aaagcaatca ctaaaaagat
    13981 ccttggtgac aatggaaaaa cagaatttgt tgaagtcact tctaaaactc ggattccatt
    14041 attgaaaaac ggaaatatcg atgcaattat tgcaacgatg acgatcacag atgaacgaaa
    14101 aaaacaggtt gacttttcag atgtctattt cgatgctggc caagctttgt tggtaaagaa
    14161 aggaagccaa atcaaaagtg tagatgattt gaatgcttct acaacggttc tagcagtcaa
    14221 aggttctaca tcggctgcga atatccgaca gcatgcacca gatgcaaaaa ttttagaatt
    14281 agaaaactat gcagaagcat ttactgcttt acaatctggt cagggagacg cgatgactac
    14341 ggataatgcg attttgttag ggattgcaga tgaaaatcca gagtatgagt tagttggtgg
    14401 aacgtttact aatgagcctt acgggattgc gatcaacaaa gggcaagaaa acttcttgaa
    14461 agctgttaac caagcgctag aggaaatgca tgcagatggc acatacgata aaatctatca
    14521 aaaatggttt ccaaatgaaa ctgaaggaaa agtagagtaa gggggagagg caatgagcga
    14581 attgatacaa acttatggac caatctttgt cgacgggttc aagatcacat tgttttcgag
    14641 tgtcttagca cttgtgttta gtttgattat cggaacgtta atggcaatct tccaattatc
    14701 aaagaataaa gtagtgagcg ccttagcaaa ggcatatgta gaatttttta gaaacattcc
    14761 attattaatc atcgtgatgt ttttttatgt tgtcgtaccg atttattggt ttaatctaga
    14821 tggattccaa gcaggtacga ttggattaac gatctataca tctgctttta ttgctgaaac
    14881 agtacgttca gggattcaaa ccgtaccaaa aggtcaaaca gaagcaggac tatcttctgg
    14941 ttttacctat tcagaaatca tgcgttatat tgttttaccg caagcattca aaatcgttat
    15001 cccgccatta ggcaaccaat ttatcaacct cgtaaaaaac tcatctattt tagcaatcgt
    15061 agctggttta gatttgatgt atcaaggaga cttgatcgct agtgaaacat tcaatacctt
    15121 cgatacgtat atcatcgttg ggttatttta cttagttatc acgctaccgt tatcttactt
    15181 aatggtttat cttgagaaaa aatgggcggt tcgttcatag aaggagggga aatacatgga
    15241 ttttagcggc gctttttcat ggatgaatat ccgtttttta ttggaaggat taaaggttac
    15301 tgttgaagtt tcattgtttt cgatcatttt tagtttcttg atcggtggtc tgacaggtgt
    15361 gattcgtttt gcgaatatcc ctttcttttc caaaatcctt ggtgtagtga ttgatattat
    15421 acggaatctt ccattattat tgatcatttt cttcacttac tttgccttac ctcaaatcgg
    15481 cattcagatg aacatcttct ggtccgctgt cgcagcatta acgatttttg agtcagctat
    15541 gttgtcggaa attttccgag ctggactcaa tgctgttcca aaaggacaga tggaagcagg
    15601 attatcaacg ggactgactt atgtagaatc gatgcgaacg atcgtgttac cgcaagcatt
    15661 taaatcaatg atcccggcaa ttgtgagcca attgatttca ctgatcaaag atacttcatt
    15721 agcagtaatc atttctttac ctgaactttc tcatcaggca cgtattattt atggacagaa
    15781 caccaattat gtgcttccga tgttcatcat catgacactt atgtacttcg tggtatgtta
    15841 cgcgctttct ctgctttccg gttacttgga aaagagacgg tacagttatt aatagatgat
    15901 tcttttagcg gttgtggcaa actaaagtca caaccgcttt tcctctttcc attcgaaaaa
    15961 aagagatttc gattgtttta agcaagtaag agcacttgaa aattcacgct aaaaagtaca
    16021 caatagggag gatagaattt attgaaaaaa aggatgatac gattgacaga taatcgccct
    16081 atcggattta ttgattcagg tgtcggcggc ttgactgtag taaaagaagc cctgaaacaa
    16141 ttaccgaatg aaaatatttt atttgtagga gacacagcac gctgcccata tggccctaga
    16201 cccgcggaac aggtaatcca gtatacttgg gaaatgacgg attatctggt ggagcaagga
    16261 atcaagatgc tggtgatcgc ctgcaatacc gcaactgcgg tggctttaga agaaatcaaa
    16321 gctgctcttt ctattccagt catcggtgtg atccttcccg gtactagagc ggcagtaaaa
    16381 aaaacacaaa ataaacaagt tggcattatc ggtacgattg gtacggtaaa aagtcaagct
    16441 tatgaaaaag cactgaaaga gaaagtacca gaattgactg tgacaagtct tgcttgtccc
    16501 aaatttgttt cagttgtcga aagtaatgaa taccattcat cggtggcgaa aaaaattgtg
    16561 gcagaaacat tagctccttt aaccactaaa aaaatcgata cattgatttt gggatgcacc
    16621 cattatccat tattacgccc catcattcaa aatgtaatgg gagaaaatgt tcaactgatc
    16681 gattctggag cagaaacagt aggtgaagta tctatgctgt tagattattt caatttgagc
    16741 aattcaccgc aaaatggtcg gacattatgc cagttttata caactggctc tgccaaactt
    16801 ttcgaggaaa tagctgaaga ctggcttgga atcggacact taaatgtaga acatatcgaa
    16861 ttgggaggaa aataaggatg cgtcatgacg ggagaaaagc ccaagagctt cgcaaactgg
    16921 agcttcaaac aaatgttttc aaatatccag aaggatcggt agtgatccgt tttggtgata
    16981 caacagttat ttgttctgca acaatagaaa attctgttcc cccttttttg agagaaacag
    17041 gaacaggatg ggtgacagca gaatatagta tgctgcctcg agcaacgagt acgagaaatc
    17101 gtagagaaag cagcaaaggg aaactttctg gtagaacaat ggaaatccag cgtcttattg
    17161 gtcgttcctt gcgtgcagta gtagacttgg aaaaattagg agaacgtagt atcatcgtag
    17221 actgcgatgt gatccaagcg gatggcggta ctagaacagc aagtatcact ggggcatttg
    17281 tggcattgaa attagccatt gaaaaacttt taagagaaaa agaattgtca gaagatccaa
    17341 taaaagaaca tcttgctgca gttagcgtag gaatcttacc agatgggact tgcgtcacag
    17401 atttggatta ccaagaagat tccgcagcac ttgtagacat gaatcttgta atgacagaat
    17461 ctggaaaatt cgtggagatt caaggaactg gagaagaagc aacgtttgat ggtgaacagt
    17521 tgaatgaaat gctctttttt ggaaaaaacg cgattgaaga tttgatcaaa gagcaaaaac
    17581 atgctttgct aacagagttt gctcaaaatg atgagcggat agaagaaaca aaaacaatca
    17641 tcattgcgac aagaaatcca ggaaaagcag aagagtttcg aaatatgttc aaagaagcgg
    17701 gatatcatgt aaaaacatta cttgactatc ctgaattgcc agatgtggaa gaaactggca
    17761 gcacatttga agaaaatgcc cgattaaaag cagaaacgat tgcacaattg cttgatcagc
    17821 cagtcttagc agatgattca ggtttgaaag tggatgcttt aggcggtatg ccaggaatct
    17881 attctgcacg ttttgcaggg gaacaaaaaa gtgatgcggg gaataacgcc aaattattat
    17941 atgaattgac agatgtgccg gatgaaaaaa gaacagcaca attccattgt acgttagtat
    18001 tcgcggcacc caaaaaagac agccttgtag tagaagcgga atggcccggt cgagtagccc
    18061 gtataccatc tggcgaaaat ggctttgggt atgatccttt atttatccca gaaggtaaga
    18121 aacaaacagc agcagaatta tcgagcgaag aaaaaaacaa gatcagtcat cgggctcaag
    18181 caatgaaaaa attgagtgcc gagtggaaac aatggctgga aggagagaga tagatgcggt
    18241 atttagtagt aagtgataat catggagaca gagatatcct cgttgactta gtagatcgtt
    18301 atcgttctga agtggatatc tttttccatt gtggtgattc ggaattagaa gcttctgacc
    18361 cattatggga tacattccaa gtggttcaag gtaattgtga ttatggacca ggattcgaac
    18421 agaaaaaagt gatccaaact ggtcaggata cagtattcat gactcacggt catttatcga
    18481 atgtccgatt tggtttgaca cagttagcaa tcgaagctcg agctgcaact gccgatatgg
    18541 tgttttttgg tcatacccat caaataggct gtgagatgga tcagaaaatc ctgtttttga
    18601 atcctggtag catttctcag cctagaggcc cgatccaaat cccatcatat gctcttatcg
    18661 aaagtttaga tgaccaaatt tctgttcaat actataaccg tgcccatcag gcagttgaag
    18721 agttggcctt ttctttttcg agagagcgct gaataaaaaa actctaattt ttaataaaaa
    18781 taagctttat tttatgaatt ttgcatccgg tttcggtaaa atagtagtgt tgaatgaaat
    18841 agaaatggag gccatcagat gattggacct atagtaagag aaatgctgct ggaaaatcag
    18901 gaaacgtttt tgattcctgc agaaaatgtg gcaaatgtta tgtatcatca tccattgtcc
    18961 catggtttac ttgtgttatc gaaggtcggt tattccaaaa ttcctgtatt aggaaaagat
    19021 gatcactttg taggactagt aagtttatca gatgtggtca ataaaatgat tgacttgcaa
    19081 acaatcagca tggacccgtt agaaggacta acggttgctg atgtgacaga aacagatgtt
    19141 ccgacaattg atgaaaattg ggaactagaa gaagtactcc atttgttagt cgattcgcct
    19201 tttttaccgg ttgtcacaga agatcggatt ttcaaaggaa tcattacaag aaaagagctg
    19261 cttaaagccg taaacttcat ggtgcatgaa ttagaacgtc gtaatatatt gtctccgaaa
    19321 atcgaagaat taaaagaaca aatcgatatc gtgagctaaa gaacgagaaa ctaaaagata
    19381 atcaaaaaat aagtagaaaa aacagcgtac cagttttgac tttatcttga aaaagaggct
    19441 gggacaaaag cgtttaactc caagaaataa gaaggaattc acgaaaattg cttttcaaat
    19501 ttttgtgaat ttcagcttat ttccgaagga gttgcttctg cttccgccgt ttatacgtgt
    19561 ttagagcgtg ggacaaaagt gttctttact tttgtcccac gctcttttta gtgagattcg
    19621 ttgcatcgtt tgtccaaatt attttccgac agcaattgga ctgttcggaa tcgtgaaacc
    19681 agaagctgtc aattctttga cataggagct caagaactct tcttttaagg catattgttt
    19741 tccgttcaat gcgtagcaga ccgtacgaat cgcaaaattg ctgtttccaa gatccactaa
    19801 tccaaagata gaaggttcag tttggagctc ttcttggtat ttttcagcta atgtacgatt
    19861 tactcgatca atgatctcat agattttgtc atatccttct tcaggaacaa tccgaatatc
    19921 taaaagtact tgcatatttg cacgagagag attgctgatc gtggtgatgt ttcgattcgg
    19981 gatgaaatgg acagtaccat ccgttgcttt cagctgaagg gtacggatac caacagatac
    20041 gacggttcct tcaatcgtta agtttgctag cttgatgtag tccccaacat ccatctgttg
    20101 ttccatgata ataaaaaatc cggtaataac atcactcatg aacccttggg caccaagacc
    20161 gattgccaca cctgcaattc cggcaccagc caaaagtgat ccgatcggca caccgatagc
    20221 agataaaatt gcatagataa aaaagaaacc aagggtataa tgaaaaatag tatttaaaag
    20281 actatgtaaa gtctttaagc ggctctcgtt tagaatggct tttttagaat actgattaaa
    20341 agacttatca atcagatatt ttcccacacg gtgaagaatc caaaaaagga cgatcaaaaa
    20401 aatcagatat aaactttttt ggataaaggc agccaaaatg gcgtcccaat caatcccgtc
    20461 ccaaaaccgc tgaaacgcat ttactttgct gacagcttga tctgtcaatg tctcgccaga
    20521 agagtctgtc gtaccggcag ttgctaataa tgaaaacata aaatcctctt ttctaaaatt
    20581 tgattctttc tgtattgtac caagaagttt tcaaaaaagg aaatagcaaa aataactata
    20641 atgaaggaaa aaagctgaaa ataaaatgac aaataatatg gataatgata aaatgtggag
    20701 aaaataacga aggtggtaag tatatgcaaa tcgattggaa caatctaggt ttttcttata
    20761 tcaaaactcc ttggcgtttt attgccaaat ggaaagacgg acaatgggaa gaaggagaat
    20821 tgacagaaga taattacctg acgattcatg aaggctctcc agcgcttcat tatggtcagc
    20881 aatgttttga aggtctaaaa gcttatcgtc gaaaagacgg caaggtcaat ctctttcgac
    20941 ctgaacaaaa tagtcgacgg atgaatcaaa gtgctagacg attgctgatg ccaatggtcc
    21001 ctgaaaagat gttcgttgat gctgtcaagc aagtggtaaa agcaaatgaa gattttgtgc
    21061 cgccctatgg aacaggcgct acattatact tgcgcccttt actgattggg gtcggtgaaa
    21121 acattggtgt ccatccagct ccagaatatt tatttgtcgt cttctgtacg ccagtaggag
    21181 cgtatttcaa aggtggacta aaaccaacga attttattgt atctgattac gatcgtgctg
    21241 ctcctaaggg gactggtgca gcaaaagtcg gcggaaatta cgcagcgagt ttacttccag
    21301 gaacagaagc aaaagaactg gattactcag attgtgttta tcttgatcca gccacacata
    21361 cgaaaatcga agaagtaggt gcagcaaatt tctttggaat tacaaaagac ggaaaattca
    21421 tcactccgca atcgccctct atcttaccaa gtatcacgaa atattccttg ttgcagttag
    21481 ctgaagaacg actaggactg caagcaattg aaggagatat tttcattgat gatctagatc
    21541 aatttgcaga agctggtgca tgtggtacag cggctgttat ttctccaatc ggtgggattt
    21601 atcacaataa caatcttcat gtattttata gtgaaacgga agtaggacca gtaacaaaac
    21661 ggttgtatga tgaattgaca ggtattcaat ttggagacat agaagcacca gaaggctgga
    21721 ttgaagtcgt ggaataattt caaagtaatg agttgaaaaa aacgtaaaaa gaaaaaatca
    21781 ggaagagact ttaaaaagtt ttttcctgat ttttatatgt tttactttaa agaatgcaac
    21841 aaaagtttat gaaagatgga cacctttgtc aacgtagata atatcaccga tgattccgct
    21901 ggaaagtggg ctgattaaga aagcacaagc attaccgact tcttcgatcg tcacaccttg
    21961 ctgatcaggc gtacgagatt cagataactg gatcagtttt tgatagtctt taacacctgt
    22021 gacagctaat gttttgattg ccccagctga gattccattg acccgaattc ctttaggcga
    22081 gaactcagct gccaaataac ggatagcagc ttcaagagaa gctttcgcaa tacccatcat
    22141 gttataattc gggattgcgc gttctgaacc tagataagtc atgctaacga tcccgctgtt
    22201 tggtgcaaga aacggttgtg cgtattttga tacagcaatt aaagagtagc tgctgatatc
    22261 ttgagctaat tgatagccgt ctctggaaat atcagacaca tttccggaca attcttcttt
    22321 gttggcgtaa gcaactgcat ggacaaggcc gtggatctcc ccagcatatt caccgatggc
    22381 attcattgct ttttcgatgc tttcgtcgct agaaacatca cattctacag tgaatgcttc
    22441 ttcgccgacc aatttgacta atgatttttt cattcgttca ttttggtaag tatagataat
    22501 ttctgcccct tgtttcaaca ttgcttcagc acaaccccaa gcaatgcttt ttttgttagc
    22561 gacgcccata atgacgattt tttttccttc tagaaatgac ataatgactc tcctttgttt
    22621 ctgataaaaa tttgatagtc gtaaaaaaat agagaataat agctaaaata acttcttgat
    22681 ttcttaatta ttagtcaaaa tgttttgatt gtcaaactat tttttcttaa attaaaaaaa
    22741 gattgctaaa tatttaggaa tatgatactt tgatagtcaa agtaatgaaa atggcaattg
    22801 cctgaaagaa ggagtttaat tatgtcttac gtattatctg ctactgaagt aatggaattg
    22861 attcctaatc gttatcctat ttgttatatt gattatgtag atactttaga accaggaaaa
    22921 aagatcgttg cgacaaaaaa tgtaacaatc aatgaagatt ttttccaagg tcactttcct
    22981 gacaatccag tgatgccggg tgcgttgatt ctagaaacac tggcacaagc aggttcgata
    23041 cttatcctaa aatcagaaga gtttctagga aaaagagctt atatcggtgg gatcaataag
    23101 gccaaattcc gtcaaaaagt tgttccagga gatgtgctga aatgtcattt tgaaatcacc
    23161 aaaatgaagg gatcagtcgg tacagcgtta tctgcagcat atgtagatga taaaaaagtc
    23221 tgtgagtgcg agttcacgtt catcgtcaac caaaatgctt gactataaaa cctgatatag
    23281 caaaacaaaa ggaagcttac ttgcttttta tgtaaaaaga agacgcctga atcctagcat
    23341 acgttgtcat ctatgcagga ttcagacgtt atttttttat ttttgttttg cttcttgcag
    23401 tatattgatt ttatcgattt ttacttcttc ttttggtttg tctgaactat ctgtttcgat
    23461 atttgcaata gcatccacga catccattcc ttcaatcact tggccgaaga cagtataatg
    23521 gccatctagt gaaggataac cgccgttttt ataagcgtcg atgattgctt gaggatagtc
    23581 gtcttttaaa agaccatcat gcatatcatc tgtattttga acgataaaga actggctgcc
    23641 gttactgtta ggatcttgtg agcgagccat agataacgca cctcttatat tataaaggtg
    23701 gttgttgatc tctgtttcaa atccttctcc ccaaatgctt tcccctccag tgccatcgcc
    23761 tttaggatcg ccaccttgga tcatgaaatc tttgatgacg cgatggaaag tcagtccgtt
    23821 gtagtaaccg tcttttgcat gtgtcataaa gttttcaacc gcttttggtg cgtgttcggg
    23881 aaataatttg attttgattg tgcctttatt cgtcaccatt tcgaccagat cttcattttc
    23941 ggcgacatct ttcgtcaatt gtggtaattc caatgcgttc aaatcgacgc tactggcagt
    24001 cgtgctttcc gcagtagatg tactttttga actttctgta gacgaactag aagaagtcgt
    24061 gttgtttgca gaacaaccag cagcaaacag caatgctgct gctaaactaa tacttaaaat
    24121 aactttattt ttcttcataa ctgttccttt ccaatttact attttgttat ctttaatgat
    24181 aacaaaatag agggaaaata cctacttaaa ttattggaat ttatcattta ttttaaaaga
    24241 aaaagaaaag gtgtagacca tttactttgt gtttgctata atgtaagtgg atacaaaaac
    24301 gaaaagatgc aggaggaaat ggtaatatgg gaaaattagg aatctcgatt tatccagaac
    24361 ggtcaacatt tgaaaaggac aaagcgtact tggatttagc tcataagtat gggtataaac
    24421 gggtttttac cagtttgctg cagatcaatg atgataaaga aaaagttctt tcagaattta
    24481 aagaagtagt tgattacgcg aatagcctag gcatggaagt aatggttgat atcaatccag
    24541 cgttatttga acagttggag atttcttacg atgacttatc ttttttccat aagatgggtg
    24601 cctacggggt ccgcttagat atcggattca caggagcaga agaagcaaaa atgacgcgca
    24661 atccttttgg tatcaaaatc gagatcaata tgagttcggg cacgaattac gttgacaaca
    24721 tcatgagtta ttcgccaaac acggataatt tattaggttc tcataatttt tatcctcatc
    24781 gatactctgg tttaggatac gaacactttg ttttttgttc agaaaaattc agaaaatata
    24841 atttgaatac gatggcattc gtcaattcgc aatctgctga gtttggccct tggcctacgc
    24901 aagatggctt gtgcacgctg gaagaccacc gagatcttga aattgcgaca caagtgaagc
    24961 atttaatcct tacaggattg attgatgata tttctattgg aaatgcgtac gcaagtgaag
    25021 aagaattgaa agaaatggca gaagcattta acgcggatta tccaacattg aaagtagata
    25081 cggaagaagg tattacagaa aacgaacgaa tctgcttgtt tgataacctt catagttatc
    25141 gaggggatcg ctcagaatat atccttcgtt caacgatgac tcgtgtatac tacaaagata
    25201 aagatttccc gcctcataat acgcgagata tgcatcatgg ggatgtactg attgacaatg
    25261 aagggtacgg tcaatacaaa ggagaaacac aaatcgcctt gaaggatatg aaaaacgacg
    25321 gacgtgtcaa tgttgtagga agaatctccg atgacgaatt attcctcctt gactttttga
    25381 aaccatggtc aagctttaaa ttaattgaaa ataaaaaata gataattagt tattgcagaa
    25441 ataatccgct agaaatagcc agttatttct gcttttttat tttgtttttt tatagg
//
LOCUS       DBBGSZ010000037        22856 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.038, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000037 DBBGSZ010000000
VERSION     DBBGSZ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.038"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            15..284
                     /locus_tag="ACIZE5_002080"
     CDS             15..284
                     /locus_tag="ACIZE5_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109197.1"
                     /translation="MKIDYLELINEIAKYKTGEEIEILRDVYDQLEEAGIEGINNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLSELEQV"
     gene            289..453
                     /locus_tag="ACIZE5_002081"
     CDS             289..453
                     /locus_tag="ACIZE5_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109198.1"
                     /translation="MDLKTFTAQIELMHQEALRQSASYEDKWLNTFHGGRESALDQVL
                     KLLKGERRDG"
     gene            446..745
                     /locus_tag="ACIZE5_002082"
     CDS             446..745
                     /locus_tag="ACIZE5_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109199.1"
                     /translation="MDKKAAMKRIIELTHSENWQEDKEIVTEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            745..1062
                     /locus_tag="ACIZE5_002083"
     CDS             745..1062
                     /locus_tag="ACIZE5_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HGC6109200.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILDEYME
                     DRE"
     gene            1059..1232
                     /locus_tag="ACIZE5_002084"
     CDS             1059..1232
                     /locus_tag="ACIZE5_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109201.1"
                     /translation="MMMPKEIYSDALRGARNQLKMAKRTYEIRPTIENERRVKAIRRR
                     CSIYGELQKEDSK"
     gene            1229..1642
                     /locus_tag="ACIZE5_002085"
     CDS             1229..1642
                     /locus_tag="ACIZE5_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HGC6109202.1"
                     /translation="MIPRFRAWNKKTQSFIDYGDLVLDLRSGKIYAGDIGLVESTIDV
                     TDQIELMQSTGLKDKNGIEIFEWDIVSVSVRNGFDYLDNKVCVVKNSIGHSGLVCATV
                     DEDLEYQIFNTELFEEYTYEVIGNIWENSELLEVE"
     gene            1639..1977
                     /locus_tag="ACIZE5_002086"
     CDS             1639..1977
                     /locus_tag="ACIZE5_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109203.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDMHGKSKSAIKLFGAIEIYADDF
                     PNLWLKEEAE"
     gene            1978..2199
                     /locus_tag="ACIZE5_002087"
     CDS             1978..2199
                     /locus_tag="ACIZE5_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109204.1"
                     /translation="MFKIAFYLFDYKDDSFKKVYFHHWNDSKPVFTKNKRRAQEYFDE
                     RSANKDIVQLKKAESPSAKTLSIRLEEKE"
     gene            2196..2501
                     /locus_tag="ACIZE5_002088"
     CDS             2196..2501
                     /locus_tag="ACIZE5_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109205.1"
                     /translation="MNIKVYLKRNLARFPRSWDTNSYPFEVEEESYLMSANMIEITRD
                     DADEFDKKRSCYFVPNPMYTAVIEDYHISDRFILIDLERPKKRVKQYRRCGFSTKKW"
     gene            2525..2728
                     /locus_tag="ACIZE5_002089"
     CDS             2525..2728
                     /locus_tag="ACIZE5_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HGC6109206.1"
                     /translation="MNTRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQCVAD
                     ASETIRKFGISILNDDRKWEEMR"
     gene            2725..3021
                     /locus_tag="ACIZE5_002090"
     CDS             2725..3021
                     /locus_tag="ACIZE5_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109207.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKARKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHLYNHSAIIRIENTMECDKRLAKSKENLAVARLVDMEVIKSK"
     gene            3099..3515
                     /locus_tag="ACIZE5_002091"
     CDS             3099..3515
                     /locus_tag="ACIZE5_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HGC6109208.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLVQYR"
     gene            4265..4609
                     /locus_tag="ACIZE5_002092"
     CDS             4265..4609
                     /locus_tag="ACIZE5_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HGC6109209.1"
                     /translation="MTEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            4614..4895
                     /locus_tag="ACIZE5_002093"
     CDS             4614..4895
                     /locus_tag="ACIZE5_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109210.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            4998..5312
                     /locus_tag="ACIZE5_002094"
     CDS             4998..5312
                     /locus_tag="ACIZE5_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HGC6109211.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            5290..6984
                     /locus_tag="ACIZE5_002095"
     CDS             5290..6984
                     /locus_tag="ACIZE5_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HGC6109212.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            7004..8182
                     /locus_tag="ACIZE5_002096"
     CDS             7004..8182
                     /locus_tag="ACIZE5_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HGC6109213.1"
                     /translation="MGIFQKAVGYFTKKATVSLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            8145..8831
                     /locus_tag="ACIZE5_002097"
     CDS             8145..8831
                     /locus_tag="ACIZE5_002097"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HGC6109214.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            8831..9991
                     /locus_tag="ACIZE5_002098"
     CDS             8831..9991
                     /locus_tag="ACIZE5_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HGC6109215.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            10001..10876
                     /locus_tag="ACIZE5_002099"
     CDS             10001..10876
                     /locus_tag="ACIZE5_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109216.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIKIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            10873..11184
                     /locus_tag="ACIZE5_002100"
     CDS             10873..11184
                     /locus_tag="ACIZE5_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109217.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            11174..11527
                     /locus_tag="ACIZE5_002101"
     CDS             11174..11527
                     /locus_tag="ACIZE5_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HGC6109218.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            11517..11918
                     /locus_tag="ACIZE5_002102"
     CDS             11517..11918
                     /locus_tag="ACIZE5_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109219.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            11911..12315
                     /locus_tag="ACIZE5_002103"
     CDS             11911..12315
                     /locus_tag="ACIZE5_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109220.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            12327..12932
                     /locus_tag="ACIZE5_002104"
     CDS             12327..12932
                     /locus_tag="ACIZE5_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HGC6109221.1"
                     /translation="MAKTTTVTTFDNISIKRISFNFKNATNAISTDCNGQLDGETEMQ
                     RIVKKCGSTEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDERIKSGIYSYGPDSVG
                     EDFSLAAEIVDDFEEKNKLIGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFGK
                     FYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            12952..13314
                     /locus_tag="ACIZE5_002105"
     CDS             12952..13314
                     /locus_tag="ACIZE5_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109222.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            13317..13499
                     /locus_tag="ACIZE5_002106"
     CDS             13317..13499
                     /locus_tag="ACIZE5_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109223.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            13516..16935
                     /locus_tag="ACIZE5_002107"
     CDS             13516..16935
                     /locus_tag="ACIZE5_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HGC6109224.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASESEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLTKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITVIAGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQAFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWVSIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISSIFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
     gene            16986..17723
                     /locus_tag="ACIZE5_002108"
     CDS             16986..17723
                     /locus_tag="ACIZE5_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HGC6109225.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVVGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINYFNCTGLSKIQIYRNGLR"
     gene            17733..20024
                     /locus_tag="ACIZE5_002109"
     CDS             17733..20024
                     /locus_tag="ACIZE5_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HGC6109226.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYPISGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITASQAWQNAKTLAKPVIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKRLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            20048..22150
                     /locus_tag="ACIZE5_002110"
     CDS             20048..22150
                     /locus_tag="ACIZE5_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109227.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGDYDYSGNPNLLSKLSYDLIE
                     NQNTSAGTLSKGENSFKYNKISAEVEGGVELYYKRRGIANWLPSNKTLVMTVKLRAGA
                     DYSPVDGKLILIRYRYVDSGTGKIVLDLPINSNSITQEWKEFSITGTTPTFSPQAYHP
                     WIQFRAQDGILGEIEMSYDIKIEEGSTATPFQPNLLAEPYNMCREYPNENIADHTVKF
                     PIESGDHQIYQGYTEEELMIGQTYTITLKGTKPASQTFVAYNHWTARLGELKPVDGLT
                     DVWSLTFTPTNVVASSPKLFRVYQYPQSTVGACRIDWLKIEKGDTRTPNISEYKYRGT
                     GMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINSQLTASINE
                     VDTTAKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKLYREGKTVS
                     IYFVALNGKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKW
                     RRNSSYGSDYTFAITYTI"
     gene            22167..22316
                     /locus_tag="ACIZE5_002111"
     CDS             22167..22316
                     /locus_tag="ACIZE5_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109228.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            22313..22759
                     /locus_tag="ACIZE5_002112"
     CDS             22313..22759
                     /locus_tag="ACIZE5_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109229.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            22761..>22856
                     /locus_tag="ACIZE5_002113"
     CDS             22761..>22856
                     /locus_tag="ACIZE5_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HGC6109230.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEE"
BASE COUNT         8124 a         3393 c         4903 g         6436 t
ORIGIN      
        1 taagaggtgg aaaattgaaa atcgattatc tagaactaat taatgaaata gcaaagtata
       61 aaactggtga ggaaatagaa atcctgagag acgtatatga tcaactcgaa gaagctggaa
      121 tcgaaggaat taataatgat cgttcgagtt ggagtaaact cagatactat ttcgcactct
      181 atatcgatac aacacaatta agaaatttag cttatacaaa attactattt gttgattgcg
      241 ttaaaggatt gcaaaaacat cttagtgaac ttgagcaggt gtaatcagat ggatctaaaa
      301 acatttacag cacagatcga actaatgcat caagaagctt taagacaaag cgcctcgtac
      361 gaagacaagt ggctcaacac gttccatggt ggacgtgaga gcgcacttga tcaagtactc
      421 aaattattga aaggggaacg tcgggatgga taagaaagcg gcaatgaaac gaatcatcga
      481 actgacacat tctgagaatt ggcaagaaga caaagaaata gttacagaag tccaaaagct
      541 cggtaaatca atgtggactg aaaagcccaa acggagaacg ccgagaaaga ttgcaatttg
      601 gcatggtgat cgaattctag taacaggtac tgctgaacag ttatctgaaa ttactggtct
      661 gagcaaaaac attatttggg atagagctag gagcttatgg attgattcaa aaggacgaca
      721 gtttaggtat gtggaggaga gataatggat ctcattacac aatacagtga catcatcctc
      781 aagaaaatca tgatgaagat tcagaaagac aaaaaatcaa aagaacgagc tgaattagtt
      841 aagttagaaa tggctgaaac aggagcagga gtgcgaagta gcaggcattg gaaagcagca
      901 gcaaacattg aattttatta caacgaaatt caaaaagggt tcgatcagat gcgtgagctg
      961 gatcggcaaa caaattggag caagaaactt catcaagatc gtttcaaatt tgtagagaag
     1021 tataaagaga tattagacga atacatggag gacagagaat gatgatgcca aaagaaatct
     1081 attcagatgc attaagaggt gctagaaatc aattgaaaat ggcaaaaaga acatacgaaa
     1141 ttcggcccac aatcgaaaat gaacgcagag taaaagcaat tcgccgtaga tgttcaattt
     1201 acggcgagtt acagaaggag gacagcaaat gataccgaga tttcgagcgt ggaataagaa
     1261 aactcagtca tttattgatt atggtgattt ggttttagat ttgagaagcg gaaaaattta
     1321 cgctggggac attgggttag tggaaagcac cattgatgtg actgaccaaa ttgaactcat
     1381 gcaatcaaca gggctgaaag ataagaatgg cattgagatt ttcgagtggg atattgtatc
     1441 agtcagcgtg cgaaatggat tcgattattt agataataaa gtttgtgttg tcaaaaattc
     1501 aataggacat tcgggattag tgtgtgccac tgttgatgaa gatttagagt atcaaatttt
     1561 taacacagag ctgtttgaag aatacacgta tgaagtcatc ggaaatattt gggagaatag
     1621 cgagttattg gaggtagagt gattatctta gctactgact acatcgattc tttaaaagat
     1681 gaaaatggga atgtcccagc attgctaaat tgtggaatta aaagcaagaa tagaatcatt
     1741 ttgttacgga tatcggctga tttagcaaaa tatctttatc tgagcaagac agcagtatat
     1801 tacactgcgg ctacacgtta tcagtacaag ggaaaaacaa tcagtcagga ttattatgat
     1861 cgtttaatca gtcctgacat gcatggaaaa tcaaaatcag cgatcaagtt atttggcgca
     1921 atagagatat atgccgatga ttttccaaat ttatggttga aggaggaagc ggaatgaatg
     1981 ttcaaaatag cattttatct gttcgattac aaagatgatt cgtttaagaa agtttatttc
     2041 catcactgga atgatagcaa gccagttttt acaaaaaaca agaggagagc tcaggagtat
     2101 tttgatgaaa gatcagcaaa taaagatata gtgcagttaa aaaaagcaga atcaccatct
     2161 gcgaaaacat tgtcaattcg attggaggaa aaagaatgaa tattaaagtt tatttaaaaa
     2221 gaaatttggc caggtttcct cgaagctggg atacaaattc ctacccattc gaggtagaag
     2281 aagagagcta tctaatgtct gctaacatga tagaaattac aagagatgat gcggatgagt
     2341 ttgataaaaa aagatcatgt tactttgttc cgaatccaat gtatacggct gtaatagaag
     2401 attatcatat atccgacaga tttattctga ttgatctaga aaggcctaag aaacgagtta
     2461 aacagtatag acgttgtgga ttttcaacaa agaaatggtg ataacaaaac agaggtgaag
     2521 aaaaatgaac accagacatc gcagaataac aaaactaaga aaacaggaac tgaatgtact
     2581 aaagacaaag tttgaaaaag aatatggaat ttcagcagaa gaaacatata aagtggcaag
     2641 tcagtgtgtt gctgatgcga gtgagactat tcgtaagttt gggatttcga tattaaatga
     2701 tgatcgtaaa tgggaggaaa tgagatgaaa ctaaaagacg gattttacgc tagtagtcat
     2761 ggtatcggcg gtttaatgct agatatgccg acaaagaacc ctaaagcacg taagaaacca
     2821 aaattcaaag tcggtgacat ggttcgctgc gaagcagaag gattcatcta tccatttcgt
     2881 ggatatgtag agcatctcta taatcactca gcaatcattc gcattgaaaa cacgatggaa
     2941 tgtgacaagc ggttagcgaa aagcaaagag aatttagctg tagcgagatt agttgacatg
     3001 gaagtaatca agagcaaata aaaaaagccg gatcgctccg actgatgtaa taaatccgac
     3061 aagtttatta tatcacataa aaggagcggt ttgacttgat gcaattgtta cgagaggtag
     3121 atttcaaaca gacaagatgt aatgcgagag atgtgctgaa gaactttcgg cgtttggagc
     3181 ggatggcagg tcgctctttg atagatatta agtcgccgat tattacggat atgccgaagg
     3241 cgccgaagca tggcaataag gcagaagacg cgatcattca gatgatggat atagaagcgg
     3301 agagagatgc gattttagcg gctttgatgg ctcttagtct gattagccgt cagatactct
     3361 actacagttt ctgtgacgta aacaagcact ctaattatga aatagggcaa ttgatacgag
     3421 gatacggaga gaagaatgta gagaagctga aatccatcgc attgatcgaa tttgctgaag
     3481 catacaaaaa aggcgtgtta gttcagtatc gttaattttg tagggttttt gtagggatag
     3541 tgtagggttt ttgagcggtt taacgtgata ttatgatagt gtcgaaagat tagtgatagg
     3601 tctaagacaa aataataata aaaggaacat cgttttatta ttgtttcaca attaagcttc
     3661 gatagacagc agcggaaata ttaagaataa ggatgtgaat tttaactcct tctaaattgt
     3721 tcttattatc tatcatcagt tgctgtctat tgtcattatg tcactgtggt ggaaaggtgt
     3781 atcgctcatc taaaatttag gtgcaaactg caaggttcga ttccttgcca gtgactttgg
     3841 taaccgaggc atcggcggtt taaaaatata ggggtgcgca atttcgtacg cgttttgtgc
     3901 atcttgtagg ttgctattac ataattggtt gggttagatt gagttttggg attcggtaca
     3961 aatgaatcgt caaatgactc aagcacagga tcggaaacgt ccctgcctgt gcattacata
     4021 ttagatcact ctttgagtgg tctttttatt ttgcgtaaag gaggcacgac gatgtataga
     4081 ccacaatact tagaacagaa gcatgaagta atcactgtgc aaaacggtaa cggtgagata
     4141 gtacgaaagt atagaagacc aataaagagc gatacatata aacggaagga aagcaatgaa
     4201 gttattccat tgtatggcaa aagaatagct aagtattaaa taagattgcg aaaggagatg
     4261 ggacatgacc gaggaattct atagatggtt attacagttg ataagagaag atcgtttggt
     4321 taagttctat cagtctccta aatggcgcag gcttagagag aaagcgatga aacgagatca
     4381 ctatgaatgc caagagtgta gaagactagg taagtatcat agagtagaga acgttcatca
     4441 tataaaggaa gtcaaggata gacctgactt agctttagat ttagataatc ttatttgttt
     4501 atgtgttgaa catcataatg aagttcatgg cagatatctt acagcgttag ataaacaaga
     4561 gaagaagata gaaagcttcg ctaacttcga tgcaagtgaa aggtggtaag tgcatgatca
     4621 tcaatgacaa tggcagagag tatgatacag aaaagattga agagtattca tcttatactc
     4681 agggattaat taaacgtttg atatacgttc gctatgtagg tattagggat ctgttatcag
     4741 ataactgttg tagtaaatac aaagtgaatc aagtaagaga agcgttgaat aaagataata
     4801 acgtcgaaag aataaaaaat gtttttggat atagtattga agagattaat tattacattg
     4861 acttcgctga agctttcatt ccgatggtga gataaccccc ccttaaaata aatcgcaaat
     4921 tttttggggg tgatgaaacg gagggggctg tcaggaaaag agattttttc gaactttatc
     4981 atgaaaggag ggctaaaatg tttaaaaacg aattgtctca aaatcgctac agagaaaaat
     5041 tacgccgctc tttaataagc caattggaaa gtcagaaaac aaatattgag ccattcttag
     5101 ataatgttga tcgttatatc agtttatggg aaacggcgat atcactggaa gaagatatat
     5161 ccgagaacgg cattagactg gagaatggta aaaagaatga atcagtagcg ttgcttgttt
     5221 ctgtcaacaa acaaatggga ttgatgttgg ataaacttgc cattactcct gaattggtag
     5281 gtgaagcaaa tgaatcaatt cctgagttat aagcatattg aaaattggtt caaagctata
     5341 gaagaaggca ctatcaaggt atgcaaagag caattattgc taaaaaatta tctagaagaa
     5401 agagtcttta ctagagaaga tatttacttc gataagcaga tggtagagga ttcaatcaat
     5461 ataccagcac aatactttcc attcgaatta attccgtggg aaaaatttct acaatgtttt
     5521 atttatggtg ttcgatggaa aaaagataaa acactagtgt tcaatagata tctttcatta
     5581 atgggacgtg gtaatggtaa aactggtttt gcttcttgga acaacttctt tctactaacc
     5641 gctaaacacg gtattaaaaa ttatgatatt gatatctatg ccaataatga aagccaagca
     5701 aagactagtt ttgatgatgt atttaaagta attaaagatc atcctgattt agataaaaaa
     5761 gtatttaaag ctacgaagga agttattcaa aatatcgcta caaacagcaa acttcgttat
     5821 aacacggcaa atgctagaac aaaagatggg aagcgaccag gtgcaaaccg ctttgatgaa
     5881 attcacgaaa atgaagatta ttcaatgata aatgtggcta cttctggtgg tggtaaaatt
     5941 cgagattata gagaatttta tgatacaact aatggtcatg ttcgtggtgg tccgcttgat
     6001 gacattatag aagaatcaaa aatgattctt tctggagaac ttggaattga caaggatgga
     6061 gcagaatttt ctagtttgtt tccatttatt tgtcgcttgg ataacgataa tgaagttgat
     6121 gatcccgaca tgtgggaaaa agcttgtcca actattaatt acaatgcaga tttaaaacgg
     6181 aaaatgtttc aagaatactc tcaaatgcaa cgtaatgctg gtttaagact tacgttcatg
     6241 accaaacgaa tgaacagacc tatggaagat acacgatttg ctgttgcttc atatgatgat
     6301 gttctgcata cgaaagaaaa agaatttcct gaaaaaatgg atgaagtgat aggaacagtc
     6361 gattttgctg atagacgaga ttttgccagc gttgggttgc taggaaaata cgataaagat
     6421 gtttatttta cacaacatac ttttatccac gaatcagccc ttcgattaca aaacatcaaa
     6481 cgagaggtta tagatatttc tatagatcaa ggaaaatcac agatcgttca tggaaaaaat
     6541 atagaagctg attatattgt aggttggttt cttgaaatga gtaataaata ttatattaaa
     6601 aaaatcgcta tggatatgta ccgtgcaaaa atattgaagc ccgctttaga agaagcaggt
     6661 tttactgtgg aaattgttcg aagcggatct gttacacatg gtatgttaaa agatctggtt
     6721 gatgaccttt ttattaatca acgtttattt tttggtgacg atgcgattat gcgttggtat
     6781 tgcatgaatg tatatgaaga gcatatttct aatggaaata tacgctatga aaaaatagaa
     6841 cctgaaacta gaaaaacgga tggctttttt tcattccttc atggtttgaa ttttttagat
     6901 gatatttatg attctgctcc tgtaacagtc acaaatagct cagtagaaaa tacaggaact
     6961 ggatttactc ctctagtatt ctaacttgaa aggaggtgag aaagtgggga tttttcaaaa
     7021 ggcggtagga tacttcacaa aaaaagcaac ggtttcttta gaagaatact tttgtaaatt
     7081 gcaagttgat tttgtgtatc gaaaatttgc gattgaaact tgtattgatt tgattgcaaa
     7141 tgcgatgagt aaagcggaat tcaagtcata tgaagatgga aaaaataaaa agaatgatct
     7201 ttactatagg ctgaatgtag ctcctaataa gaaaaataat gcaacagaat ttagaaaaaa
     7261 actgatcagg agattaatat tctacaatga agtattgatc gtttctccgt ctaataattc
     7321 tagcgaaata tttattgcgg atagttggga tgtcacagaa tatgcattga aagatgatgt
     7381 gttttctcaa gtgcaaatta acaacatagt ccttgataga gaatttctag aaagtgatgt
     7441 tatctatata aaatacgcag atcaacaaat taggcaacta gtcgatgcgt attatcaagc
     7501 gtatgggaaa ctcatttcta gtgccatgaa tgtttacaag cgctctaacg ctcgtagata
     7561 cgtactgaaa gggaatttat tccgaccgca agacaataca acacaagatc aaatcaataa
     7621 aatgatgaca tcacaattta aggcttttat ggaagctgat aatgcaggtg cggtatttca
     7681 attacaaaat gagtacacat tagaagattt cagcggaaac ttccaaagca attcaagaga
     7741 tataaaaaac ttaatagacg acatctttga gatgacagca gcagcgtttc acgttccgaa
     7801 aaacctacta aagggagaca tgagtgggtt atcggatcaa gtggacgctt ttttaatgtt
     7861 cgaaatcata ccgattgctg aacttattca ggatgcgttt aacgctagtc tctatgaagt
     7921 agaagaatac ttgtcaggga attttgtacg tgtggataca actatgatca agattactag
     7981 cttcaaagat ttggttgacg ctattgatgt aggcattaga aatggagtat ttacaatcaa
     8041 cgaaggaaga gagcgcgttg gaaatgatcg ctctgataag gcgatggcag atgaaatatt
     8101 tataactaaa aacaatcaac aagtatcgaa aggaggtgag gcgaatgacg acaatgaaaa
     8161 catttctagc agtaaagaat gaaggcgcag taccgcaaat ttttattcag ggatttattg
     8221 gttctagttg gttctttgaa gggaatactg acaagggaat caaaaatatt ttggatagtc
     8281 taggtgatca agaagaaatt gaagtagtaa ttaattcaaa cggtggagac gtatttcaag
     8341 ggattgctat tgggaactta cttaagtcaa ataaagcaaa agttaacgtt gtgattaacg
     8401 gcttagccgc tagtgctgct tcaattatcg caatggctgg cgatactata aaaatctaca
     8461 acaatgcaca attgatgatt caccgcgctt ccacatacgg agaaggaaat gtcgatgact
     8521 tccgtacgat tgctgaccaa ctggaatcaa ttgataaatc ggtaaaggct tcatataaaa
     8581 cacgattcaa tggcacagat gaagcattgc aagaacttct tgaaaaagaa tcgtttatgg
     8641 atgcagaaac agctttgagt tatggattgg tcgatgaaat tatcgatgca gaaaatagct
     8701 caggtactga agctaaaaaa gaacaaagcg ttgaagaaat tttgaatgac gttaaagaaa
     8761 aaagagcaga aaaaattgct gcatttacag cagcattaaa taaaacattt ggacaaggag
     8821 atgtaaaata atgacagtta aaaatttaaa aggtgtaaca gctgcaagcg accaattgat
     8881 gaaagctttt aaagatggta acgaagaatc ttttagcgca gctatggtaa gcttatctaa
     8941 ggaaattcag gataaaattt tagaagaagc aacagcaaaa aatcaagatc aattagtatt
     9001 aatgaaccgt ggtcagcgtg tattaactac acaagaaaca aaattctata acgaagtagt
     9061 gaaaaacgaa ggttttgcag gggtcgaaga attagtgcca gctactgtat ttgaacgtgt
     9121 atttgaagat ttagaacaat ctcatccact attgcaaaaa attacttttg ttaacacaac
     9181 tggtgtaaca gaatggattg tgtcacgtgg agtcaatcca gcatggtggg gtaaactttg
     9241 cgaagctgtt aaaaaagttt tagataatgg ctttgatgta attaacatga agcagttcaa
     9301 gctatcaggt tatattcctg tatgtaaggc aatgcttgat ttaggtccag tatggttaga
     9361 tcgttatgtc cgtactgttt tagtagaatc attgagaatt gcattagaac aagcaattgt
     9421 tgatggtact ggtaaagata tgccagtcgg aatgatgcgt gacatgagca aacaaactag
     9481 cggagaatat gctgaaaaaa aagcagaacc tattacagct ttagatgctg taactatggg
     9541 cggtttgatg gcgcgactat caaaattcaa tatcgaaggt gtgaatgatc cgatttatcg
     9601 taatgtgaat ccttctgatg tggtcctaat tgtgaatcca actgattact ggtctaaagt
     9661 attcccagct aagactgtac taactgctaa tggagaatac gtacaagtat tgccagtacc
     9721 agtttcagat ttgcagtcaa cggctgtgcc agaaggaaaa gcagttattg gggtagcctc
     9781 agattacttc atgggtgtag gatctacact aaaaattgaa gcttcagatg aataccattt
     9841 tgttgaagac gaacgcattt atctagctaa acaatatgca aacggtcaac ctaaacgtaa
     9901 cgatagtttc attgtattag atattagcgc tttgggaact actactacaa ctacaaaacc
     9961 aacaaccaca acaactacaa cacaagcgta ggtgatcaga atgaagtata ttctttgtca
    10021 gccggcaatc aatcggttta aatgggagct tgaagtttgt ttaactaatc tgaagaaact
    10081 aggaatcaaa gatatcgtat tgcttttcag cagacacgat gatcagattc ctattttttt
    10141 tgagaaggaa tatggtgttg aagttcatgt gtacgatgat ctgcgggacg acaaagagta
    10201 tattccttcg attaaaccat atttatggtg gaaatattta gaagaagatc attcgcgtga
    10261 ggacgaccga tatttctata tcgattcgga tgtcattttc aataaaagaa ttaatttgcg
    10321 caaattacct tctaaagatg atgtttggta ttgtagcgac tgctgtagtt atctaagtct
    10381 tgattatatt agaagctgtg aaaacggaga aaatattcta aaagatatgg caaacattgt
    10441 aaatgttaca gtagaatctt tggaaactat aaacactaat tcaggaggcg cacagtgggt
    10501 tattaaccgc cctaaagcga attattggaa aaaggtttat ctggattcta atcggctata
    10561 tcgctacctt agagggcaaa aaacaaatat aaaaatctgg acagccgaga tgtgggcaca
    10621 gctttggaac atgatgtatt tcaatattgg tcctaaagtt cacgaggaat tagacttttg
    10681 ttttgctact gatccaatag aaaaagttaa agaagtaaaa atcttacaca atgctggagt
    10741 aacaacaaac gatgaagatt tatttttcaa agggagatac gtgacttcta cgccttttga
    10801 tgaagattta tcatttgtaa acaagaaaaa atgctcttac gcatatgtta aagcaattaa
    10861 ggcggtggtt agatgacgcc tgaacaagtg actgaagaat tgctaatagc tgtgaaggat
    10921 aatatttacg ttacctggaa cgaagaagat gagtcaatta aaaagatgat agctaaaaat
    10981 gctgtttatc ttcaaagtaa agtgagtaca acactttctt tttctcctga aagcttagaa
    11041 tacggattgc taatcgaaag atgtagatac gactggaatc gtgctttaga tgagtttgaa
    11101 caaaatttcg ctagtgagtt attaggtttc attcaacatt atgcgctaca agaatatatt
    11161 gcaggtgatg tgaatggcga ataatcgtag actcgaagaa acattcaacg atggttggtt
    11221 aaagattttg acgcaaacta ccaaaagaaa tgaactagga aaaaagattg gtgtagaaga
    11281 tacagaaatc acttctttaa aatttagaaa tctttccatg agagatagtg atataacagc
    11341 tatggatgcg atgggatcga aattaactaa gaaagtaaag actccatttc atccaatcgc
    11401 caagaaattt aataaagatc aatattttat cgtaatcgat agtatgcgtt acaacgttat
    11461 ctatgccgat tacgataatt tttatatcta tttttatctt gaaagtgtgg gtgaatatgg
    11521 tgattgataa ttctaaagaa aaagaacgtt taaataagca aatttctgct atcaaaactt
    11581 ccttagaaga gcattttggc ctcaaactct ttcaagactc cgtaggcgag gatgagctac
    11641 ctgatgattt taattacttc attctcgaaa caggagaaat agaaatgatc actgagccaa
    11701 aatatagcgt gggtcaaaat ctatatctaa ctttctattc agaaaataga gaagatttaa
    11761 caggagattc actagatatt atttcattga ttcaaaatcg ttcgattcgt tttcagagaa
    11821 tggatcccaa tcatttaaaa ctagagaacc aagatcgcta tatcgatcaa ttggtattta
    11881 cgtttagacg attattgaag agtgattgtc atggctaaaa atagttggga gctaaaaata
    11941 aatggacatg atgaacttct tgtgcggatg gaacgctatt caagcgagag cgaacgactg
    12001 attaacgaag cattgaaatc aaaaggttcg gctattgcag tggataggat tacagaaaaa
    12061 attcctgttt ctgaagcaga tttaagaaga gggcaccaac acgcaaaaaa tagtcgtcca
    12121 cttaagactc aatacattaa tttgggtttc atcattagac ctacaagaaa atttgagtat
    12181 ttaaaatatc ctgatttggg gataggtact tctaaaagaa atcagccgga cgaatttatg
    12241 agaagaggat taggtcttgc acttgatcca attacagaac ttctgattcg tcaattcgat
    12301 aaattaaata aataggagga acaacaatgg ctaaaacaac aacagtaaca acttttgaca
    12361 atataagtat taaaagaatt tcttttaatt ttaagaatgc aacaaatgca atttcaactg
    12421 attgtaatgg acaattagat ggcgaaacag aaatgcagag aattgtaaaa aaatgcggtt
    12481 caacagaagt aaaatcgaaa tctaaaccaa tcaatatgac ggtaacaatt actgcacatg
    12541 taccgatgga agtttatcga cgcttcaatg ggttgaaaca agatgaacgt attaaatcgg
    12601 gaatttactc ttatggtcct gattccgtag gggaagattt ctctcttgct gcagagatcg
    12661 tggatgattt cgaagaaaaa aataagctga ttggtatgtt agcatgcact tcgaatacag
    12721 gattaacatt ctctattgaa aatggtgcgg atgaagtagc tgcgttagaa ctagaaacaa
    12781 aagttatgca agatgaattt ggtaaatttt atcatgaagc aattgttgca gaacttgaag
    12841 aagacttaac agatcaatgg atgacgaatc tatctgctga tgtgattaaa aaaacttcag
    12901 ttgtgacaac tacggccact caatcacagt aaaaaaaacg gaggtagcga aatgaacgaa
    12961 gattactcaa aaattgaact aaacgatgga acaattttga atttagaacc taaactgaat
    13021 atcaagaaat tattgatgat caatagagat tttaacacag acgagtttgc aaaaatgact
    13081 gtgggaaaag gatccatgga tatttctgtt attcaaggtg caaaggctgt gtatattgct
    13141 taccgccaag cgaacatgac tgattatatt tcattcgatg aatttatcga taaatgggat
    13201 tttgatatgg ctactgccag ctatatttat caattgatga tgttcaaaca agcacgcgat
    13261 gcttatcaaa aagaatttga aaaagcaaat aaggaaaaaa agcttcaaaa gtaaaaatgc
    13321 caaagctctt agttgaaacg tgggtcgatg tctattcgat gttgaccgac gttttttcta
    13381 tgccttcaga tttggtttta agcgatatct gtttagatga cattttgcaa atggcttaca
    13441 acaagagtgc ttatgaagga tggaaaaact atgcaataaa ccaatcccag aaaaactaaa
    13501 gaaaggaggt aaaaaatggc taaaaagaga acagaagcag aagtaacatt catagctaac
    13561 gatgacggat tgaaatctac gttaaaagaa atcagtgctg aattaactaa aaatagagca
    13621 gaattaaaac tagaacaagc tcaattacaa cagactggtt ctgaatcaga caagttagga
    13681 agtaaattat cttctttaga aaagcagtat gaattacaaa gtcaaaaagt tgaagtaact
    13741 agccaacgtt tagccaatgc caaaaaatat tatggagaaa attccaccga agttcagaaa
    13801 cttgagagag aactgattaa ccaacaaaca gcgcaacaac gtttgtcaaa cgaaattgat
    13861 aaaacgagta atgcactagc tcaagcaaaa ggcgaaatac agacgtacga gtctacaatg
    13921 caacagttgg atagtgaaca aaaaaatgtt caagctagtg cttctctgat tgaatccgaa
    13981 tacaaaaaat ggcaagcaac tgctggtcaa tcagcttctg aatccgagaa attagcgaaa
    14041 gcccaagaat atgtttctca acaatctgaa aatgcagaga aaacgataga tatcctgaga
    14101 cgacagttag aagctacaca gtctgagttt ggcgctacat ccacagaagc aatgcagatg
    14161 gaggcgaagc ttaatgatgc tgaacgtgaa tttgaagagt taggacaagc tgctaaaaat
    14221 gtagatacaa ctaacttgga cgatatcgga agcaaaatag atatgaataa tctaatggaa
    14281 gcttctgacg ttttaagcga cattggcgat aagcttacag aattagggaa acaagcagtg
    14341 gactctgcta atagtgtagg tagttcccag agtaaaatac aagctaattt tggtttgact
    14401 aaacaagagg ctgaagaatt aacgaatgta gccagagaca tttattataa aggttttgga
    14461 gaatcgttag atcagtccac agatgcattg attttggtaa agcgtaattt aggcgattta
    14521 aataatcaag atttacaaaa tatcacggaa caagctatgg tcctagaaaa caccatgggc
    14581 gctgatatgg atgaaacgtt acgtggtgta aatggcttaa tggtcaattt cggcttgagc
    14641 gctcaagatg caatggattt aatggtttcg ggtactcaaa acggtttaga taaaacgcac
    14701 gaattaggcg acaatatggc agaatatagc caattatgga gtcaaatggg atattcagct
    14761 gatgaaacgt tcggaatgct tcaaaatggt ttagatgcgg gtgcttataa ccttgataaa
    14821 gtcaatgact tagttaagga aatgggaata tcgttaacag atggtcgatt tgagcaaaac
    14881 atggatatgt ttagtgaaag tactagaaaa gcttttgaag agtggaaaaa tggcggagga
    14941 acacaaaaag acgttattaa ttccatgatt caagatttta gcaatatgga tggtcaatac
    15001 gaccaattaa ataaagcttc gacaatttgg tctgcgcttg gcgaagataa cgcgatgaaa
    15061 gttgtccaat ctttaactga tgttaaccat acatttgatg atgttagtgg atctgcacaa
    15121 aaaatgaatg aagattctac tactccgttg caagagttga acgggaaaat agctgaatta
    15181 aaggattcat tagctcctat aggcaacaca atcatagatg cactcgaacc agtaattgat
    15241 tttctaggaa agatggctga tgcgtttaat aatcttccac aaccagtaca ggattatgcc
    15301 gtagcgattg gcggattgac tgctgcattt actttattaa tgccaataat agttggcttc
    15361 atggctctag gtggtcctac tacattaata ataggagcag ttattactgt tattgctgga
    15421 gttatagcaa ttataaaaaa ctggggcgca attactgact ggtttaaggg aatatggagt
    15481 aaattcactg attggttggg tggtacttgg gaaagtataa aagaaggtgc ctcatcagtt
    15541 tgggatggag ttaaagaaac ctggtctgga tttgtagatt gggttcaaga tatttggcaa
    15601 ggagtttctg attggtttgg agagctatgg agcggattag ttgaaggagc ttccaacatc
    15661 tggcaaggag tccaagagac ttggcaagca ttcgttgatt gggtttcaaa tatttggaac
    15721 ggagtcaaag aagtatggtc gattatttgg gcagacattg taggaattgt tcaaatacca
    15781 tggaccttaa taacgtcatt gattcaagcc ggtattaata ttatcgtggg tatttttgat
    15841 gtagctggac agttattagg cgcagcttgg caagctgttt ggacacctat ttctgatttc
    15901 cttaaaaaca cttgggatac tatgacacaa tgggtaagca tcgcttggaa tggaattgta
    15961 actacattcc atactatatt tgatccagta gtggcatggt ggaatggtat atggacagct
    16021 attagtacta cggcttcaaa tatttggaat tcaattagtg caacagcttc tagtatttgg
    16081 aacagtatca agaatacaat cactagcttg gtacaagcag ctgctacagt aattcaaaat
    16141 atttggtcaa ctgtatctag ttggttaggt ggaatttgga attcaatcag ctctacagca
    16201 tcaaatatct ggaatagcgt gactagtagt ataagcaatg ctataaacgc agctaaaagt
    16261 gccattcaaa gtgtttggaa tagtatatct tcgtggatca gcggaatttg gaacggtatc
    16321 aaaaacactg ctttgaatct ttggaatgga attacaagca ctattagctc taaagtaaac
    16381 gatggaaaaa atgcaatttc aagcggttgg tccaatctaa caggtattgt ttccgacata
    16441 ttcaataatg ttaaaagtac aattgctaac atttgggaag gtatcaaaaa gactgttagc
    16501 gctccaattg attggatcag agataaaatc agtagtatct ttgataattt gaatatttct
    16561 ataccacata ttccgttacc acattttaaa ttgagcggag aattcaatcc attgaagggg
    16621 aaaatcccaa cgttgggtgt tgattggtat gcgaaaggta gtgtgtttaa ttctccgaat
    16681 attatcggtg tcggcgaagc aggacctgaa gcagttttac ctttgaaaag atctgtgctg
    16741 caagaaattg gtgatcgtat cttgagtagc acatcagttt catctagggc acaaacgatt
    16801 caacctgtga ataactacga attcaatttc acaattgatg gtaacgcaga tgaggttact
    16861 atgaagcaaa caactcaaca aatcattgat agcattacaa aagttcaaaa tgataatgct
    16921 tcggcatggc gttaaacagg agagtatttc tcctgttttt ttagtattaa aaaggatgtg
    16981 aaaaaatgac tgattgtata cattctataa tcgatggatt tcctgattat ttgcataaat
    17041 tggctttagc tgaaagacca accatacctt ctccaaaaag acagagagtt gaaacttctg
    17101 ttttaggaag gttaggtggc ttagtacaag attactcgtt tgaagacatg tcgtttacat
    17161 tgcactataa ctatttagag gatgtggaag accatcaagc gttcaagcaa tcgttttata
    17221 tcatgcgtca ttggttaaat tatgcaaaga aattagaatt ctctgatgat cccaacgtct
    17281 attatgttat ccagactatc gatattgggg atgcagaaaa cgatattgtt gaatggggag
    17341 agttcgatgt aaatattact gcgaaaccat tcgcaagagt tcaagaagat gtacctataa
    17401 ccgtagataa accacagtca tttaacttgc tgaataatag tttagaagaa agttttccaa
    17461 agattatcat cactccttca gctacttcat gccagttcat cttaaatgat tatgtgttta
    17521 gttttgaagg cttagtagta ggaactgacg tagtcattga tagtgatttg atgctttgct
    17581 acgaagagca atcggacgga gatattttag atcggtccaa caaaatgaag accatgcaat
    17641 atccgacatt gcaagtggat attaattatt ttaattgtac tggtttgagc aaaatacaaa
    17701 tttatcgtaa tgggttaagg taggtgaaat agatgatcga taatttaata actatttacg
    17761 ataaaaacga cgcgaataat ttagctgaac atttatatga tacgcaaggt ttaggcgctt
    17821 tgtcagactg gttaacagct actgttagca ataaattaaa cggagccgag atatttcagg
    17881 gtacttatcc aataagcgga actaatgcag atttgattgt agaaggacgt attattcagt
    17941 gttatgtaga tgaaaatcga gcaaaacagc gtctacggat ttattatgca aagacttctg
    18001 taataggcaa tacgatagaa gtaaaagctg aacctatttt caatgatata agaaaatcgg
    18061 tgttgaataa atatgacagt ggaacagaaa agatcactgc tagtcaggca tggcaaaacg
    18121 caaaaacttt agcgaaacca gttattcctt cacagttttc tttctcgtca ttagtagata
    18181 cgcttgctaa tgtgaagata gaaaaggcga attttttaga attctttggt ggaaaagagg
    18241 gatctattct agatcgattt catggggaat ttctaaaaga taataacaca ttacgtcatg
    18301 aaaaaaggct aggcacggat cataaaatca aagcgattta tactaaaaac ttaactggtc
    18361 ttgacttaga gattgatgct caaagtgttt tagttggagt ttatccattc attagcagct
    18421 cttcagaagg agaagacgag atcactctac cagaagaagt tattttcacg gattacgtgg
    18481 atgattatcc tgctggatat gtttcttttg ttgattttaa agacaaagcg actgatgtag
    18541 ccacattaag ggaagctgct aaagactggt tgaaaacaaa catagataaa caaaaaccac
    18601 aagtgagtgg ttcgattgaa ttagtaccat tgaggcatca aagaggctat gaaaaatttg
    18661 ttgatctaga aaaagtttcg atgggtgacg gagtagatgt gtatcatcca cagttaaaag
    18721 tgaatatgtc agcgagaatt gtggaatata cgtttaatgt tctaaccaat tcatacgata
    18781 aattagttgt aggaaacgtc aaaacaaact tcttagaaaa cacagagaat aatgtcagca
    18841 atttgattaa tgatgccatt gatcaattga aaaacggtgg cgaaatcagt gatttactca
    18901 atgatattgt agatcatcaa actgatatga ttactggtca aaatggtggt tatgttttat
    18961 tagatcctaa agaagcgcct agtcgtattt tgattatgga cacaccagat aagaataccg
    19021 caaggaatgt tttacaaatc aacaatgctg gtattggttt ttctaaaact ggcattaatg
    19081 gaacatatga aacggcatgg acgttagatg gcggattcaa tgcctcgttt attacggctg
    19141 gtgaaatagt aggaattact attagaggta ctacattaat tagtgatggt gctgattata
    19201 gaacaagtat tgctaatggc aaaatgactt ggtactcaaa aaaagttaac aaagatatta
    19261 tggagctaga agcacgtgat tatgtaagtg ctgatgccgg tattgtatca tacaccatga
    19321 aaactggtgg tggtttcatg attagaaatc cacagggtaa cttggttttt agtacgtggg
    19381 ataatggtaa taacagaccg tttctatctt ttggtgcgcc caatttcagg tatagcaatg
    19441 ctagttatgt aacttctggc gacggtagtt ctttaagcat taatggtagt gcgggtaact
    19501 catgggaatt taaggtagct ggtaggacta tgaaatttac tagtgatggt atgctaacgt
    19561 taccaggttg tttttttggt tcatgggaag atgggaaact tgctaggttt gaacaatcaa
    19621 cggtacaagt atataaagat tttactgtta gaggtactaa aaactcaact gtaccaacag
    19681 aacattatgg acaacgacta ttgaacgctt atgaaactcc agaatattat ttcgctgatt
    19741 atggggaagc cgttacaggt gacgatggta aagttcgtgt tgatattgac cccatgtttg
    19801 ctgaaacagt aaatctaagt cggtatatga cacatgtgac acctacagaa ctagttttgt
    19861 gtgctgttac tcatgaagat attgaccatt tcatcattga aactagtaag ccaaacgtat
    19921 tagttagatg gaatttagtg gcacaccgtc tagggtatga agatattaga ttaaaagagg
    19981 atacagcata tgatagcaca gtgcttgacc aaaaacgttt ttaaaacgaa gacaaggagg
    20041 tatataaatg gctagcagtt tatataattt ggctttagat ttcagcaaag aattaaacta
    20101 caccaaagct attatggctc gtcaaggtga taaagggatt acggtgacgg ttaaaccgtt
    20161 tctaaatggc ttgcagatgg atacgagtgg cggaacattt actttaaaag gaacaacacc
    20221 atctaaccgt tacgtagata atgttgcaac tagtgtaact agtgaagaag tcacgttttc
    20281 tcttgatggc acatttatga gtgaagcagg atattataaa cactgctacg tagaatatag
    20341 aaaagacaat caaattttaa caacgcaaga tatcattttt ttctcactag gagtgtctga
    20401 catttcgcaa ggccaagccg atgaatatgt ttcgcaatta gaagagttga ttcgaaagta
    20461 caacgaaact tttgatgctt ttatggctga aatcaaaggt agagtggata gcttaaatca
    20521 acagattact gatttaactg gtcaagctaa aacgctacaa gacaagttag atgctctgaa
    20581 agaagaaatt tctaagttag gtaacttaca agtgatgtac agtaacagca tcgacttcgg
    20641 ggactatgat tatagtggaa atcctaattt gttaagtaag ctatcatacg acttaattga
    20701 aaatcaaaat acttcagctg gaacactttc taaaggtgaa aactcgttta aatataataa
    20761 gatatcagct gaagtggaag gtggagtaga gctatattat aaacgaagag gtatagctaa
    20821 ctggctacca tctaataaaa cgcttgtaat gactgttaag cttagagctg gagcggacta
    20881 tagtccagtt gacggaaaac ttatactgat tagatatagg tatgttgaca gtggaactgg
    20941 caagattgtt ttagacttac ctattaacag taattcgata actcaggaat ggaaagagtt
    21001 tagtattact ggaactactc caacatttag cccacaagca taccatcctt ggatacaatt
    21061 tagggctcaa gatgggatac ttggggaaat agaaatgagc tatgacatca aaatcgaaga
    21121 aggctcaaca gctacaccat tccaacctaa cttattagca gaaccttaca acatgtgtcg
    21181 cgaatatcct aacgaaaata ttgccgatca tacagttaag ttcccaatcg aatctggcga
    21241 ccaccaaata tatcaaggtt acacagaaga agagcttatg ataggtcaaa cgtatactat
    21301 cacgcttaaa ggaacaaaac ccgcaagtca aacctttgta gcgtataatc attggactgc
    21361 tcgtttagga gaactaaagc cagttgatgg gttgacagac gtatggtctc taacattcac
    21421 accaacgaat gttgtggcga gttcacctaa actttttcgt gtttatcagt atccacaatc
    21481 aacagtaggc gcatgccgga tcgactggct caagattgaa aaaggcgaca cacgaacccc
    21541 gaatattagt gagtataaat atcgtggtac tggtatgcgt gattcaaaca atccaaaaga
    21601 ttatgtttgg gatctagcac cagaatatgt cgaagataac ttggccacag atattaaaat
    21661 ttctgaaatt actggtaaag caaacaatta taccgatggg aaagtatcgg agattaattc
    21721 gcagttgact gcttcaatta atgaagtaga caccacagct aaggatgctc aaacaaaagc
    21781 gaatgctaat gcgactgcta tagatgaatt agacaataag atcgatgaac gcattaatga
    21841 tacagctact accacattaa cagttacaaa cgggaatacc ggatcagcaa agctttatcg
    21901 tgaaggaaaa acagtttcta tatattttgt ggctttaaac ggaaaaagca gtggtggaaa
    21961 tgattcaacg atactaacaa ttccagaagg ctatcggcca ccaattagtt ttgagcaact
    22021 ggttggctcg atagaccgtt ctactttgaa cagtgctcag ttatctattg gtgcagatgg
    22081 agccattaaa tggcgaagaa actcaagtta tggatcggat tatacctttg caattactta
    22141 cacgatttag aaaagcgtga atcgatatga aggcagcata tagaccaatt gaaccttacg
    22201 gattcgagca aatcattgtg aatgatgaag aacatttacc ggaagaatgc acagaagtcg
    22261 aaccaccgat tccaaattgg aaaccgaaat tcaattactg ggagggaaat aaatgaaaaa
    22321 catttggaaa tatggacgta ctggcggaga gtacgcagga aaagtattgg acgacatgct
    22381 tgtatccgtt ccttacacag atcagccacc gcttgaagga attcgtgctg atggcgaacc
    22441 gttaacaatc gctgatcaaa tgtttgatcc taaattgaat caatggatta ttttagcgaa
    22501 cgcactagat cacaacgatt taaacaatct caaagcaatg tatgagtcgt tagaaaatga
    22561 gaacggcgat ttaaaacaga tcaatgccaa actcatgcta agcgatgtag caattaaaca
    22621 ggaaaatact gcattgaaag aaaaagcgga tagtttagca caaatcaatt caaaaatgat
    22681 gcttgcttcg ttacaaaata gcaaagacat ttcagaaatt aaagagcaac taaatccagc
    22741 ttcaaaggga ggtgagtagt atgtttagtt ttagcgatgt gaaaatgatg tatgattggg
    22801 gctgtttcac taacgaacaa gtaatggttt tcgttccgtt gtgcattact gaagaa
//
LOCUS       DBBGSZ010000038        22423 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.039, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000038 DBBGSZ010000000
VERSION     DBBGSZ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.039"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            6..305
                     /locus_tag="ACIZE5_002114"
     CDS             6..305
                     /locus_tag="ACIZE5_002114"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC6109231.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="ACIZE5_002115"
     CDS             378..1739
                     /locus_tag="ACIZE5_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HGC6109232.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="ACIZE5_002116"
     CDS             1761..2021
                     /locus_tag="ACIZE5_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109233.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="ACIZE5_002117"
     CDS             2035..2787
                     /locus_tag="ACIZE5_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HGC6109234.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="ACIZE5_002118"
     CDS             complement(2881..3486)
                     /locus_tag="ACIZE5_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC6109235.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="ACIZE5_002119"
     CDS             complement(3539..4513)
                     /locus_tag="ACIZE5_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HGC6109236.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="ACIZE5_002120"
     CDS             complement(4891..5610)
                     /locus_tag="ACIZE5_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6109237.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ACIZE5_002121"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ACIZE5_002121"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HGC6109238.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="ACIZE5_002122"
     CDS             7161..8558
                     /locus_tag="ACIZE5_002122"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC6109239.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="ACIZE5_002123"
     CDS             8639..9079
                     /locus_tag="ACIZE5_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGC6109240.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="ACIZE5_002124"
     CDS             9227..9553
                     /locus_tag="ACIZE5_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGC6109241.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="ACIZE5_002125"
     CDS             9554..10303
                     /locus_tag="ACIZE5_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HGC6109242.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="ACIZE5_002126"
     CDS             complement(10383..10838)
                     /locus_tag="ACIZE5_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGC6109243.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="ACIZE5_002127"
     CDS             complement(11265..11540)
                     /locus_tag="ACIZE5_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109244.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="ACIZE5_002128"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="ACIZE5_002128"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGC6109245.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="ACIZE5_002129"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="ACIZE5_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGC6109246.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="ACIZE5_002130"
     CDS             14770..17436
                     /locus_tag="ACIZE5_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGC6109247.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="ACIZE5_002131"
     CDS             17800..18552
                     /locus_tag="ACIZE5_002131"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC6109248.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18574..19728)
                     /locus_tag="ACIZE5_002132"
     CDS             complement(18574..19728)
                     /locus_tag="ACIZE5_002132"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HGC6109249.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19913..22354
                     /locus_tag="ACIZE5_002133"
     CDS             19913..22354
                     /locus_tag="ACIZE5_002133"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HGC6109250.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
BASE COUNT         7198 a         3933 c         4673 g         6619 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaag
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
    18601 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
    18661 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
    18721 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
    18781 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
    18841 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
    18901 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
    18961 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
    19021 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
    19081 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
    19141 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
    19201 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
    19261 accgacacct tgcgtcactt caccaccgct tgccaagctg taacgagcaa tatcacttgc
    19321 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
    19381 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
    19441 cagtaaatgg tggataatta ccgcactcgc ttttgaatga tcaatcccgg attctgttcc
    19501 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
    19561 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
    19621 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
    19681 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
    19741 ttacttatga taaaaaactt actttactaa ggtatcataa aaagattaaa agaaatataa
    19801 aaaagagaat atttaaggat tgttaaaatt taatcttaga aaaaaataac tggaacaaga
    19861 gctatttgtt tttacagcaa agaatggtat atttttgtag gaggtggctt acttgaaaga
    19921 agtcgttatg atagatgctg caagaacgcc gataggaaag tatcgcggaa gtttaagtcc
    19981 atttactgca gttgaattag gcacacttgt gactaaagga ttattagata aaacaaaact
    20041 gaaaaaagat aaaatcgatc aagtaatatt tggaaatgtc ctgcaagctg gtaatggtca
    20101 aaatgttgcc agacagattg ctttgaacag cggtctccct gtagatgtcc cagcaatgac
    20161 gatcaatgaa gtttgcggat ctggtatgaa agcagtgatc ttagcacgcc agctgatcca
    20221 attaggtgaa gcagaacttg tgatagccgg cggaacagag agtatgtctc aagcacctat
    20281 gctgaaacag tatcagtcag aaacaaatga atatggtgaa ccaatttcca gtatggtcaa
    20341 cgacggattg actgacgcat tttcaaatgc acatatggga ttaaccgcag agaatgttgc
    20401 aacacaattt tctgtgagca gagaagagca ggatcgctat gccttgtcgt cccagttgaa
    20461 agcagcacat gctgtcgaag ccggtgtatt ttctgaggag atcatcccag tcaagatttc
    20521 tgatgaagac gtgttatctg aggatgaagc agttcgtgga aatagtacat tggaaaaact
    20581 gggcacgtta cgtacagtat tctcagaaga aggaactgta acagcaggaa atgcttcccc
    20641 gttgaatgac ggtgcctctg tggtgatcct tgcatccaaa gaatacgcag aaaataataa
    20701 tctgccttat ttagcaacca tcaaagaagt agcggaggtc ggtattgacc caagtatcat
    20761 gggaatcgct ccaatcaaag ccattcaaaa attgacagat agatcaggaa tgaatttatc
    20821 aacaatcgat ctttttgaga tcaatgaagc atttgcagct tcttctatcg tagttagcca
    20881 agaactgcag ttagatgaag aaaaggtcaa tatatatgga ggagcaatcg cattaggcca
    20941 tccaattggt gcaagcggtg cacgtatctt gactacatta gcttacggat tgcttcgtga
    21001 acagaagaga tacggtattg cttcattatg tattggtgga ggtttaggct tggcagtctt
    21061 gttagaagcg aatatggagc aaacacataa ggatgtgcaa aaaaaaaagt tttatcagct
    21121 tacgccatct gaacggcgca gtcaattaat agaaaaaaat gtattgacac aagaaactgc
    21181 gttgattttt caggaacaaa cactttctga agagctctcc gatcacatga tcgaaaacca
    21241 agtgagtgaa gtggaaatcc caatggggat cgcgcagaat tttcaaatca atggcaagaa
    21301 aaaatggatt ccgatggcaa cagaggaacc atctgtcatt gcagctgcaa gtaatggtgc
    21361 aaaaatctgt ggaaatatct gcgcagaaac acctcagcgg ctgatgcgag ggcaaatcgt
    21421 tctatcagga aaatcggagt atcaagcagt gatcaatgca gttaatcatc gaaaagaaga
    21481 gctgattctt tgtgcaaatg aaagttatcc ttcaatcgtg aaacgcgggg gcggtgttca
    21541 agatatctct actcgggaat tcatggggag tttccatgca tacttatcta ttgatttttt
    21601 agtggatgta aaagatgcaa tgggcgctaa catgatcaac tcgattcttg agagtgtggc
    21661 aaacaagtta cgggagtggt tccctgaaga agagattcta ttcagtattt taagtaattt
    21721 tgctacagaa tcattggctt ctgcctgttg tgaaatccca ttcgaacgct tagggagaaa
    21781 caaagaaatc ggtgaacaaa ttgccaaaaa aatccaacag gcaggggaat atgcgaagct
    21841 tgacccttac cgtgcagcaa cgcacaacaa agggatcatg aatggtatag aagctgtagt
    21901 ggcagctaca ggaaatgata cacgtgcggt tagcgcttcg atccacgcct acgcggcaag
    21961 aaatggatta taccaaggat taacagactg gcagatcaaa ggggataaac tagttggaaa
    22021 actaacggtg cctttggctg ttgccacagt aggcggagct tccaatatcc tgccaaaagc
    22081 aaaagcatct ttagctatgt tagatattga ttcagccaag gaactagcac aagtaattgc
    22141 tgcagtaggg ttagctcaaa acctggctgc tttgcgtgca ttagttacag aaggaatcca
    22201 aaaaggccac atgggacttc aagctcgttc attagcgatc tcaattgggg ctattggtga
    22261 ggaaatcgag caagttgcga aaaaattacg tgaagcagaa aagatgaacc agcagacagc
    22321 tatacaaata ttggaaaaaa tccgggaaaa ataaaaaagc aatatcttta gaagaataaa
    22381 gcaagattta cagttatttt atttactgca gatcttgctt ttt
//
LOCUS       DBBGSZ010000039        22322 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.040, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000039 DBBGSZ010000000
VERSION     DBBGSZ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22322
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.040"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            2..400
                     /locus_tag="ACIZE5_002134"
     CDS             2..400
                     /locus_tag="ACIZE5_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HGC6109251.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            384..1079
                     /locus_tag="ACIZE5_002135"
     CDS             384..1079
                     /locus_tag="ACIZE5_002135"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HGC6109252.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1673..2560)
                     /locus_tag="ACIZE5_002136"
     CDS             complement(1673..2560)
                     /locus_tag="ACIZE5_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HGC6109253.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2745..3584
                     /locus_tag="ACIZE5_002137"
     CDS             2745..3584
                     /locus_tag="ACIZE5_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGC6109254.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3780..4754
                     /gene="sgrA"
                     /locus_tag="ACIZE5_002138"
     CDS             3780..4754
                     /gene="sgrA"
                     /locus_tag="ACIZE5_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HGC6109255.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5052..5408
                     /locus_tag="ACIZE5_002139"
     CDS             5052..5408
                     /locus_tag="ACIZE5_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109256.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5540..6568
                     /locus_tag="ACIZE5_002140"
     CDS             5540..6568
                     /locus_tag="ACIZE5_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109257.1"
                     /translation="MYWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWIS
                     LLRISLQRMKQGHSITYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTE
                     QAYLYFMFGVMNTYLEEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLY
                     VNLAMIHLYSRVFGTKKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNT
                     YYEKNRRLIFQYCMLVRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYS
                     ASADQLPDIVISDYPIDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSI
                     LEKLDFVN"
     gene            complement(6594..7034)
                     /locus_tag="ACIZE5_002141"
     CDS             complement(6594..7034)
                     /locus_tag="ACIZE5_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGC6109258.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7194..7700
                     /locus_tag="ACIZE5_002142"
     CDS             7194..7700
                     /locus_tag="ACIZE5_002142"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGC6109259.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            7868..9780
                     /locus_tag="ACIZE5_002143"
                     /pseudo
     CDS             7868..9780
                     /locus_tag="ACIZE5_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
     gene            9785..10786
                     /locus_tag="ACIZE5_002144"
     CDS             9785..10786
                     /locus_tag="ACIZE5_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC6109260.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(10988..11194)
                     /locus_tag="ACIZE5_002145"
     CDS             complement(10988..11194)
                     /locus_tag="ACIZE5_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HGC6109261.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11840..12688)
                     /locus_tag="ACIZE5_002146"
     CDS             complement(11840..12688)
                     /locus_tag="ACIZE5_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGC6109262.1"
                     /translation="MSISIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12852..13754
                     /gene="gnd"
                     /locus_tag="ACIZE5_002147"
     CDS             12852..13754
                     /gene="gnd"
                     /locus_tag="ACIZE5_002147"
                     /EC_number="1.1.1.343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydrogenase
                     (NAD(+)-dependent, decarboxylating)"
                     /protein_id="HGC6109263.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            13756..14757
                     /locus_tag="ACIZE5_002148"
     CDS             13756..14757
                     /locus_tag="ACIZE5_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="HGC6109264.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14754..15038
                     /locus_tag="ACIZE5_002149"
     CDS             14754..15038
                     /locus_tag="ACIZE5_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HGC6109265.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15071..15868
                     /locus_tag="ACIZE5_002150"
     CDS             15071..15868
                     /locus_tag="ACIZE5_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HGC6109266.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            15882..16715
                     /locus_tag="ACIZE5_002151"
     CDS             15882..16715
                     /locus_tag="ACIZE5_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGC6109267.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16733..17590
                     /locus_tag="ACIZE5_002152"
     CDS             16733..17590
                     /locus_tag="ACIZE5_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGC6109268.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17612..18121
                     /locus_tag="ACIZE5_002153"
     CDS             17612..18121
                     /locus_tag="ACIZE5_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HGC6109269.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18158..18559
                     /locus_tag="ACIZE5_002154"
     CDS             18158..18559
                     /locus_tag="ACIZE5_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109270.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18671..19024
                     /locus_tag="ACIZE5_002155"
     CDS             18671..19024
                     /locus_tag="ACIZE5_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109271.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19058..19501
                     /locus_tag="ACIZE5_002156"
     CDS             19058..19501
                     /locus_tag="ACIZE5_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC6109272.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19518..20603
                     /gene="uxuA"
                     /locus_tag="ACIZE5_002157"
     CDS             19518..20603
                     /gene="uxuA"
                     /locus_tag="ACIZE5_002157"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HGC6109273.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20596..21309
                     /locus_tag="ACIZE5_002158"
     CDS             20596..21309
                     /locus_tag="ACIZE5_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC6109274.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(21516..21665)
                     /locus_tag="ACIZE5_002159"
     CDS             complement(21516..21665)
                     /locus_tag="ACIZE5_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109275.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            22061..22261
                     /locus_tag="ACIZE5_002160"
     CDS             22061..22261
                     /locus_tag="ACIZE5_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HGC6109276.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         7686 a         3429 c         4624 g         6583 t
ORIGIN      
        1 gatgacgatc tttgaaacgg ttgtaacaga tgttggtata gaagcagaag tattcaggaa
       61 agaaaaaata atgattttat ttggagatga agcaccggaa acattaacag attattgtta
      121 taagattgaa ttgaatcagg taagaaaaga aataacttgt gatatgaagc tctgttttga
      181 taaacaaatg tatgtaatca cagcagtagg agatgttgtc caaactaatt tgaatgaatt
      241 aggacatatc acgataaaat ttgatggatc tcatgagccg gaacttccag gaacaatgta
      301 tgtagaagat aaggaaatgc cgcatttaag aaaggggaca atcattaaaa tcgatcaaga
      361 ggatcagaat gggggaaagc tatatggaaa tcatgcttga tacagcaaat acaaaaagta
      421 tttattcttg tcaacagttt ttgaatttaa caggcgtaac aacaaatcct acaattctga
      481 aaaaagaagg agcgtcaaac ttcttctcgc atatgaaaga aatcaaaaaa ataatcggac
      541 agattcctat ccatattcag acaataggaa gaacggaaga agaaatgata gaggatgctc
      601 gagttatcat agaagaactg ggaaaagata cgtttatcaa ggtgccggtg aatcaagcag
      661 gccttcaagc gatcaaaaag ttgaaaaaag aaggttattt gattaccggt acagctattt
      721 acacagaatt acaagggtat ttagctatta ataatggagc agattatatt gcaccttatt
      781 ataacaggat gcaaaatcaa ggcattgatg ctatgaaagt gattgattcg ttgcggactg
      841 agatcgaacg tacgcaaaga ccaacaaaaa tattagcagc tagtttcaaa aattgtgaac
      901 aagtcactac agccattcga tctggagctc atgcgataac gttaggtaaa gagctactag
      961 atcaagtatt agagatgccc tcgattgata aagcagtgag gggcttccaa gaagattggg
     1021 tgcaaacttt ccaagcagaa acgattggtg aactaaaaaa ggtcgctgat tacttctgaa
     1081 tcaatttctc cataaaataa acgatagcct tctcgaaaac tcgaggaggc tatctgacga
     1141 ttcaatattc attaatttaa agtttgggtg actattacta actattactt atttctcatt
     1201 taaacgatgt attccctaac ctctaataca tccttgtaac tctgaagtta cgccagtttt
     1261 gaataaattt cataaaaaca aatgaaaagt gtcgcataaa aatatctttc gtgtttctct
     1321 agtataacag aataagaaga acaagtccag aagggatatt tttagtcttt tttaaaataa
     1381 cttttcagtc gagtttgagt ttatgatagt tgtttttgaa gcgatacggc aagtgaaaaa
     1441 atagggaagc atgaaagaat ctacttaatg gcgcattgat tcatgtgata gaaataaaaa
     1501 acttttttaa attatatcct catgattgta acaaatccag tgatttgttt tggtacaaat
     1561 aaaaaaaggc cccgatgaag ttgtggcaaa agtggtttgc ctcaaaaata agaaggaatt
     1621 tccaaaaatc acttctcaaa ttttgccaca tccccaattg ggtcaaattt gtttatttga
     1681 atatattttt tacataagga tctttaatag ttacattgtc ttttttcatc actttacgga
     1741 ttgttttatc catgaattcc gtatcaagag tttttgcttc ggtagcaatt ttttctagct
     1801 cagatttgta tttgtcttta ttagaacctt tatcctgttt ttttaccatt tttactagat
     1861 aatagctttg ctgataagtc gttggatctg ttacaggaat gatatcagaa acttccccgt
     1921 tttttagttt aaatgctgct ttttttactt cagtaggaat ctctggattg gttgaatcaa
     1981 aattcatttt tccatcagtt tcctttaatg ttttattttt tccataagct tgaacaagct
     2041 tggagaaatt ttctccttca tttgcttctt tttttgcttt atctgcttct tctttagtcg
     2101 aaaatagaat gatctgtgta ctaacttctg gatagaattc tttccaagca gtgtctagat
     2161 ctttatctgt taattttaca ttggctttca aaccgtattg gaaagccagc atctgtttaa
     2221 agagtttctt atatgtctct tctgtttggc caactgcttt taattgttcc ttgtagtttg
     2281 gaccgagttt tttgatttgt tcattatatt cttttgttac ttcctttgaa gaaatctctt
     2341 ttccgtatac atcatcaaat gctttgaaga caatcatttt ttttaatagt gtttgattat
     2401 ttgatttaac ttttgggtta tcataaaaat cctgaactgt aagtgttcca cctttaaacg
     2461 ttgcaatcgt ttcattggac ttgctacaac ctgagaatag taaaattgca catgctgaaa
     2521 ggcacataat tagtagttgt tttttcaaaa aatttcccat cctttcctta ttaaaaacag
     2581 tctaacagaa gaattaggga gacagtcttt cattttcgta aggttgctgt agatattctt
     2641 agttcgtaaa aatctattct ctctatgatg gagaacattt acatagtttt cacgagacaa
     2701 gaaagaaaag ggttgttaaa cttaatataa aggagggatg aaagatgatc aggattattc
     2761 ggttgattgg atctgtttta atagtcttag ttggttttgt tttaggaatt cttgtcaata
     2821 atgcacttgc ggatatgttt attggaaata gtgaatggat tggagcaatt gccggtacgg
     2881 tcggacattt agctgttttt ttactagctt tatttcttgc tagtaaggtc gaaggaaaaa
     2941 gaatagaaga ttatggtgtt tctgttcgag gaaaagactg ggggtattta gcgggaggtc
     3001 tcgttgttgg aattggagtg tttctgctta ttactagtcc attatatttg acgggggcgt
     3061 atcggttaga ttcaggaaac gcaaacattg tgccgctgat aacgagtttt attttattta
     3121 ttgcagtggg ggcatcagaa gagcttttat tccgtggctt ttttcagcat cagatgctta
     3181 gatttggtcc gttaatagca atgattggat ctgctgcatt atttgctctt ttgcacggat
     3241 tgaatcctaa catgacattt ctggcagttt tcaatatctt tttagcaggt tgctttttca
     3301 gcgcacttat ctacagtaca ggaagtttat ttacggctat tggtgctcat attacttgga
     3361 attggacaca aggagctatt ttgggtatac cagtcagcgg aacgcaagaa caaggttttt
     3421 tctccactct gatccaatcg caaaatacaa taattactgg gggaaacttt ggggctgaag
     3481 catctatatc aactacatta ttcttgttag tcttgattgt tggtttgtta ctctatgcat
     3541 ataaaacaaa gcggatgaag aaatacactg ctgtttatca ataaaagatg aagaaagcaa
     3601 ggctgatatc ggtcttgctt ttttaagtct gtcattgatt aaacgaaaaa gtaaacaaat
     3661 tcaagcgaat acacgacatc ttttgttaga ttttcacaac tgactgtcgt gttctcatca
     3721 ttttcatttt atataattcc tttatcaaat agaaggtaat tatatggaga gtgatagaaa
     3781 tgaagaaaac agcgaccgta ttatttgtta ttcttgggct gagtataatt gcagcaatga
     3841 ttggaatcag tacttctgca aatgaacggg caaatgagaa tctttcattt actgtgaaaa
     3901 ctgatcggat tgtttatgac atgacacaac aagtcattac tattccagtc aaaccaaaca
     3961 aaagcgtgaa tgctagtgat gtacatgctg ttctaacata tggttgggat ggtaatggaa
     4021 gttcagaaaa agttattggg gaagtttatt taaaagacgt acaatggacc gctggtattg
     4081 agtatacaat aatgatttct gcagaactat cgattgatga gatcaagagt aaagataaag
     4141 ttgatttgat tgttttttat gatggacaga tgacgatcac ggagaatttg aaaccaagca
     4201 gttggacagt tgttggaccg ccaagcagta cggatagcac aagtagtgaa agcagtacag
     4261 aaaacacgag cggtgaaagc agtacagaga gtacgagcag tgaaagtagc acagaaaaca
     4321 cgagcagcga aagcagtacg gagagtacga gtagtgaaag tagcacagga agcacgagca
     4381 gcgaaagcag tacggagagt acgagtagtg aaagtagcac aggaagcatg agtagtgaga
     4441 gtagcacagg aagcacgagc agcgaaagca gcacaggaaa agtaaataat gaacttgatt
     4501 tggtacctat cataccaact aaggaacaaa agagaaatgc agggagcaac ctaaaaagtg
     4561 tgctaaaaca gcctgatttt gtttctcgtg gaattgatca tcaagaaaaa gcgaaagaaa
     4621 cagataatag aaaaagcgat ttaccagaaa ctggtagtag aaccttgaac aagctaatta
     4681 catggatggg tgtgttactc attttgattg taggagcaag ctattttcgt tctctcttcc
     4741 atcgagtgaa ataaagaata aaagcaacag atctaaaatt gaataaaacg atagattttt
     4801 gagtgaatat ttcattcgag agtgctgtat tgcctggcga agttgtagct ttgccagatc
     4861 tatttttgtt tactaacata tttgagaaac aggaaataac aggaacacaa atggaaaata
     4921 agagcaagaa taattgacaa tgcacactgc gcatggtagt atctctgaaa aatcagtaac
     4981 gaatctattt gtacgttatt catgtagctg tcggaataag tctaaataat agataaaaag
     5041 gagtatgtac tttgtttgaa gaatttattg atatcaatga aaggcaagta tatcaatttt
     5101 tgaactattg ttatgaaaga gacgagaaat tatatgtggt gaaggatatc gctttagatc
     5161 taaactacac cctggctaag atgaattcgg tgattcaaca agcagaatcg ttttgcgaaa
     5221 ggtatccaga atataaatta tcttttcttt cagaaaacaa gatgataaaa gtcgagtttt
     5281 cttctcagtt tttactgagt aaagtttatt ctatactttt agagggaacg attggttata
     5341 ttttactgga ttcactttac aaaggtactt atcaatcctt agaaaatctt agtcaaaaaa
     5401 ttatataagt ttgcgtacga ttcaaagaaa attaagagaa cttaatacta ttttgaaaaa
     5461 ctatcattta tcttgcagct tgaaaaaagg taatccgata gaaggagaag aataccgtat
     5521 ccgatacttt tttcacttga tgtattggca gtcattcgac gaaaatcatt ctgatatatt
     5581 atcaagtata aaaaataaac gtcaactatt agaaaaattt gcgaaacatg cgccatatac
     5641 gcgtagtata gatagaaaga aatggatcag cctactaaga atttcgttgc aacgaatgaa
     5701 acaaggccac tcgattacgt atgtcccaga agagatgaac aaatttgtgc atccattgat
     5761 aacaaaagaa gagtttacgc attacatact agagcctttt tttgaagcaa acttctggtc
     5821 gatgaatcac atcactccaa cagagcaagc ttacctttat tttatgtttg gtgtaatgaa
     5881 cacctatttg gaagaagatt tgttggatac tccagataaa gtacaagaaa gttggggctg
     5941 gattgaatcg tctattgtag aaaattttga aaaaaacttc aagatttgtt ttacaacttc
     6001 agaaaaaaat tatctatatg tcaatttggc aatgatccat ttgtattcaa gggtttttgg
     6061 gacaaaaaag aaggtggatg cttttggaaa atcagcagaa gacagagatt ttcagcatat
     6121 atttccagtg atgtatccaa tcatgcaaca gttttttagt ggggtagctc gcagaattcc
     6181 agagcttaat acttattatg aaaagaacag acggttgatt tttcaatact gtatgttagt
     6241 cagggatatt tttataaaac acgaacaacc tgtcatattc tatattcaat caaagtatgg
     6301 taaaacacag gaattatggg caaagaaaag gatattatct atgactgaac gcccaataaa
     6361 atatagtgca tccgctgatc agttacctga tattgtcatt agcgattatc ctatcgacaa
     6421 aaaggcatat gatcaaacga atacacagat attttactgg aatggacaac ctacaaaaaa
     6481 tgattgggcg cgtctgaaag ctgaaatcat aaaaatcagg aatgagaaaa atagatccat
     6541 attggaaaaa ttggatttcg ttaattaaga aaagcagatt gtttatgcca aaattaagac
     6601 attgcaaaaa gattattttc tttaaaatcg acaagatgac cagaaagcaa gagttcgttg
     6661 agctcttgct ttcttttagt tttagaaagg aacatcctga ttttatcttc gctaaatcca
     6721 gtcaaaagtt ttgcagattg gtcgtagata atcggttttt tcaataaaga aggggatgta
     6781 cgaatctcaa tatatagttc actcaaactg agttcatcta ttctgtgaac aagattttta
     6841 taactaatag aatgagtaga gagcatttcg gtcacgccgt tgtttgtcaa ttttagtaag
     6901 tggataaatt catttttggt tagtggttga cgaattaagt tctgttcgat aaacggtata
     6961 tcatggacga taagccaacg ttttgcgcgt cttgaagacg agcagccaga acctgtatac
     7021 aatttaatca tcatacattc ctccaatagc taagtattta tgaaataata acatgaagaa
     7081 atagtcgaaa agtgccattt agaggtgtaa aataagaaaa tgttgtcacg tataatggaa
     7141 ctagctagat aagaaatact attaaatcaa gaaaaaagaa agaaggcaca agtatgtcaa
     7201 acacagccga cgcaatagta gtgatcgatt tacaaaaagg ggtatgtttt gattcttcgc
     7261 cgatacacga attagaaaca gtgacagcat tagtgaataa aagaatcaaa acatacgaaa
     7321 cgattgggaa accagttatt ttcgttcaac acgaagatgc tcaattagtg ccacaaacaa
     7381 aaccatggga gctattgtcg gaattatcta ttcctgagca cagttatttt gtgagaaaaa
     7441 cccatgcgaa ttcattttat aagactaatt tgagtgtttt attaactgaa ttggactgtc
     7501 attcgatcga attatgtggg gcacaagcag agtattgtat agatacgact gtgaagtttg
     7561 ctcatggatt aggataccag cttatgatgt gtagaggagc aacgacaact tatgataatc
     7621 cttttatgaa agcaaaggaa acaatcgctt tttacgagaa aatttgggat aaacgatttc
     7681 tgacattttt ggagcaataa gttgtttctt cgtttaaaaa aagcagaatg gatactggtt
     7741 tatccattct gctttattac gtaaaatgag aaaataatcc tgttctattt ttatgggata
     7801 aaccatttat tttttgtata aaaaatgttt gcgtttacat ataattctcc tagaaacata
     7861 aaaaggagtg aatagcttga gaacaaaaca agtattaaag ggagcgttgg tcatcttatt
     7921 tgctgtaagt acaagcgtcc cgcaatggac agtatatgga gagagcattt cttccgaatc
     7981 ggaatctcgg gaggtagaaa ccacagaaac tactgatgct ggaaatgaaa cgaaatcgag
     8041 tacttcacaa acagaaacaa atactgaaac aacggttgag acatctgtta ctagcacaga
     8101 tcaagaaacg accgctacca cagataacca acaaacagaa gaagcaacag ctacaaaaat
     8161 gtcaaacgac gaatcctctt ctgctaaagt aagtgacaaa gagaatggga cagaaaatga
     8221 tgatatcggt aaaggtgaaa atttcaatgg taaagaatat ttgaattact tcggtaaaca
     8281 gatgacagaa atacttaatg gaccaacaga agacatcaag tcaaaattaa tagagttatt
     8341 agtcactgag cttgctgtta atgattatgg tgtagataaa gagattatca aacatctgat
     8401 tgctacttat ctattgtacg atatcgcttt tgcaaaaaac agtgtgttga tgtcgatgct
     8461 tggaggtaca gatgatggga caacgcctac agaaaacaca ggcttctatc caaatacaaa
     8521 acaacttcat caaactgtac taaacaaaca agatggcaaa atgatggatg tatatgcata
     8581 ttatgtcgat caaggttcag ataaaacagt catgatccat ggcggatttc gagggaattg
     8641 gaataacggg atcgttacag aagaatacaa tgatttttat aaggccgggt ataatttatt
     8701 atttgttgat tccagagcga ctggtaatag cggaggcgat tatgtgacct atggacaata
     8761 tgagtcagat gacgtccttt actggataaa tcaagaagtt cgagagcggc catctcaaaa
     8821 gattttactt tatggtggtt cgatgggagc agctacgatg atgtctgtat tagcgaaaga
     8881 tattcctgtc aatgtcaaag gaattattga aaattgcgga tttgcatcaa ttgatgaaca
     8941 actacgtttt acgtacagcc agacagtagc ccccgcacta ccggatgcca taaaaaatca
     9001 gttagacatc attggggatc aagagcatga agatttattt atgggccttt tgaaacaata
     9061 ctattttgat caggagatgc atttggatac aaaagctgct ctacctacga ttggaatgtc
     9121 agattcattg cctaaattga ttatccatgg aacagcagat gatgtagtac ctgtgtctaa
     9181 cgcgcaaaaa ttatatgagt tatcaggagg gtataaagat cttttattag tagaaggagc
     9241 agggcatgga aaggcacagg aagttgacca tgctgcctac acgaaacatg taacggactt
     9301 tttgaaagta gtgttccatg atcagataaa cgtaaagtat gtggatgaaa acaataaaag
     9361 tctactcaaa gaccaggacg aaatccagct ttacggagct tatggagaaa attatatgac
     9421 agagcaaaag acattcgaag gatacgaatt agcaaatgtt gaaggaccga ctgaagggat
     9481 ttttaatgag acgataccaa ctattatttt ctattacaaa aaaatcccag tagctccacc
     9541 aaaaaagcaa gatccgacag agaatgcaga caataaggga aagaatgaac ctcgagagga
     9601 tcaatcaagt gatgatacgc aaccgattca gatgacagtg aaagtacaaa aaaagacaga
     9661 tgcaaaaaaa gaatgttgcc gaaaactgga gaaaagaaac attcgcttct catttattca
     9721 ggtggatttt tatctgttag cacgattatc acatggattt ggcgaagaaa gagagggtaa
     9781 atgaatgaaa tggttcaagc gaatagtgat tgcagtacca gttatcatcg tagttatttt
     9841 agtcactgta tttttgatta atcaaatcac accaaagccg attagcttgc ttgttagaaa
     9901 acaatttgac acaagtgaaa aagaacaagt atatgcccga ccagatgatt tccagcaaaa
     9961 aatcgaacaa atcgatataa aaaaagaaat atcctatcct tcaaagtaca aaaataataa
    10021 tatggatatc tacacaccga aagtggaaaa gaaaaaatta ccgattcttt tctggatgca
    10081 tggaggcgca tatgtaggag gggataaaaa tgattgtcgt gattatttgg aatatctatg
    10141 ttcagacacg cagcaaatca tcgtaaatat agattatgaa cgatcaccgg aagcaaaaca
    10201 tcctacacca gttatccaat tgaacgaagc cattcaagca gctaaaaaag agataaaaga
    10261 tcaagcagat tggtcgaata tttcgattgg tggaaattcg gcaggtgcac aaattagtgg
    10321 agaatatttg ttagcacttc aaaatgaaga aattaaaaaa gctgatcatc ttgatccgac
    10381 tttggagaac aagcagatta cgaagtttat ttctttgtct ggtctgttgg atccttctgc
    10441 acttactcaa gtaagtgata aaatctctag ctttctttat gaaaaatgtg gatgggctta
    10501 ctttgataat aaggactttg aacaatcaga gaaggtcaaa agtttagcct tggtcagaca
    10561 tgcggatcgt tggacgcaaa acacattctt aacggatgga aatacaaata cgtttacgaa
    10621 acaaatggaa gaagtaactt ctgtatttga gaaagcgggg gtgaaagtca caaaagtaga
    10681 ttatgcggag aaaaatgctg ttttgaacca tgaatatcag tttgatttca gcaataaaca
    10741 agcgcaagaa acatatcaaa agttagtaat gtttttcaag gagtaaagtc ttatgatgca
    10801 aaagaggttg taatctgtca cttagctcca agtcacaagg agcaatttca ataaacaagc
    10861 ttttcatggt ttatgaatat tgtaacttgt gactgaggag ttagagatgg caaggggcac
    10921 cttttattcg aaatttggga atatcacacg attattgtca cgatctcttt tacgtaaatt
    10981 ttataagtca gatttgttgt tttgatcgtt taaaaaaagc aacaaatccg aagcctgcgg
    11041 aggcaagaag ggacaaaaag ccgagtggta agcaaaagaa tgctggttcc actaatattc
    11101 cgttgttatt gatataaggc tgggaacaaa gatgaatagc aaataaaatc aatgcactag
    11161 cgaaaaaaag caaagaaata tggatagctt tcataagcag cacctccttt tttataattg
    11221 tatgataaat agattaagaa tctataaatg tgacaagttt gttaggatgt gaataaaatg
    11281 atcatctagc gaacttgaaa caaagatggc taatgataag caattaatga ttcagcaatc
    11341 agataggtac aaagtttacc atcatacgtc tagaccaata atagaaaata tgggaatata
    11401 atagaaaaga tttaggatac ccccaaaaga atttccccaa aaattcgatg tatcctaaac
    11461 ttttttattt tacataacaa tcatatcaac tgtgaaataa aattacaaat gataacctaa
    11521 aatgaggcca aaagccagtg ttatcaagga aatacttaat tcaccaaaat tttttttaat
    11581 tttttagaaa ataagaaaca aaaataataa aaaaaagaaa agataaattt tttactactg
    11641 tatactaact ttgttatcgc atctaacaag taactcgaat aataccaata caaccttctc
    11701 caaagatgcg atgacatacg ttctaaccca ccgactattg atgttctgta ccacccttgc
    11761 agaaccaaaa aagccactac caaatatttg gtagtggctt tttttgtttt atggattttt
    11821 cgctttttct gttatggtgc tattctttga tttcagaaat agtatgtcga actttagcga
    11881 tagaacgacg tgattctttt tcgttgtaaa acatcaaaat cacatataga gagtccaaaa
    11941 tgcttagttg agaaatacgg gaagctaaag cttcagatcg gaattctgtt tcttcagaaa
    12001 tagaaataaa aacgacatcg ccaagtttag caagggaaga attagcttgg ctagtaataa
    12061 cgattgtttt tgctccagtt tttcttacgg tttcagcaat atggattgtt tcttttgatt
    12121 gccctgtgtg agaaatcaaa acagcacagt ctttttccgt caataaagaa gcttccatca
    12181 attgaatatg gtaatccgtg ctgtgagaag ttgcgatagg ggaacgcaaa aatttatgat
    12241 aagcgtcagt tgctacaatc tctgaaccgc caacaccgaa aaaatagaca cgtttagatt
    12301 cattgataat agtagccgct ttttttagat ccttttgttg taacaacttt tttgtgtcat
    12361 ttaaagttga aatactagac tcgaacacct tttgcgccat agtgagctca gtatctgttt
    12421 tctgaatatt ttcgtggata gaaatagcag atagatcatt ttcttggatc aacatggcca
    12481 ttttaaaatc tttaaatcca ttataaccaa gtttttttgt aaattgaaaa aaagtagagt
    12541 cagcaatgcc cagttcactt gctaaattgc taataggact atgacttact ttgcttggat
    12601 tttctaaaat ataatcggcg atagcctgtt cttttgggct gaagtcgttg tacattgttt
    12661 tgatttgtag tcttatggag atgctcatga gaattcctca ttttcataat aagattatca
    12721 ttttttccgt tctcattaat gttaaagata caaggagagt aggaaaaaat caaacaaaaa
    12781 atatttttgt aaaatctatt tacaaaaaaa tttttttgta taatgagggt ataagaaatg
    12841 gaggcgctat catggaaatt ggtgtaattg gtttgggaaa aatgggattg aatttagctt
    12901 taaacttaaa agagcaccat cacaaagtac aaggactcga catttcaagt acagctgtta
    12961 gtcaggcaag agaaaatgac attcctgctt atcaagagat ctctgaattt ctagctactt
    13021 ttgagcagaa aaaaatcatc tggttaatgc ttcctgctgg agagataacc gaaaacatgt
    13081 taagaaaact ttttccaaaa ctcggaccag gagacattat tattgaaggc ggaaactctt
    13141 attataaaga ttcaatccgt cgagcagaag agtttcagaa aaatgaaatc ggttacttgg
    13201 attgtgggac ttctggagga atcgaaggag cacgacatca agcctgctta atgattggag
    13261 gagataaaga aacttttcta tccgtggaac aattattcaa agatgtagca attgaaagag
    13321 gatatctgta tgctggtgca tccggaagcg gacacttctt gaaaatgatc cataatggaa
    13381 tcgaatatgg aatgatgcaa gcaatcggtg aaggattcca acttgtacaa aaaagtgagt
    13441 atgcttttga cttggaacaa gtcgcacgtg tttggaatca tggttcggtg attcgcggct
    13501 ggctgatgga aatcatggaa gatcagttaa acgaacatcc caatttaagt aattatcggg
    13561 gaatcgtttc tgcatcaggt gaagcaaaat ggacggttga aacagcgcta gaaatggctg
    13621 ttccagttcc agtaattgca actagtttgt tcatgaggaa tctttcacag gaagaagata
    13681 gtttttcagc aaaagtagtt tcagcactaa gaaatgggtt tggcggacat gaaatagttg
    13741 aaaagggtga gtaaaatgcc agattatcat atagcaatcg ttaattccag cagtttcgga
    13801 agagtctttc cacaccactt ggaaagatta aagtcagttg gagacgttca tttctttact
    13861 gttgatcaag agattccagg aaaagaacta gcggagttac ttaaaggatt caatatcatt
    13921 attgcaagtg ttacgccatt ttttcgacga gatttttttg aaaacaaaga tgaactgcta
    13981 ttgatttccc gacatggtat tggttacaac aatattgatt taaaagcagc aaaagaacac
    14041 cagacaatcg tatctatcat acctgcttta gttgaacgaa atgctgtagc agaaaataat
    14101 ataactaatt tgttgtccat gcttcgacgc acgacacaag cacaagcaag agtcaaggac
    14161 gatcgatggg aagatcgggc ggagttcgtc ggtaggacgc tgtttaacaa aacagttggt
    14221 gtgattggtg caggaaatac cggaagcgga gtaatcgaaa ttttgcgtaa cggttttcgc
    14281 tgtgatgttc tagcttatga tccttacaaa tcagatttat acatcgaaag ctttggtgca
    14341 aaaaaagtag aacttcaaga attactggaa caatcagata tcatttgttt atgtgcgaat
    14401 ttgacagaag agaactatca catgatttct gataaagaag tcgatcagat gaaagaaaat
    14461 gtttatctat ctaatagtgc aagaggcgct ctagttgatg aagaagcgat gattaatggt
    14521 ctgaaaagcg gaaagatcgc aggatatgcc acagatgttt tagaagaaga accgggacgt
    14581 caagatcatc cgtatttagc gtttgaacaa gtagtgatta cgccacatat atcggcctac
    14641 acaagggaat gtttagaagc aatgggtgaa aaatgtgtca gagatgtcga acagatcagt
    14701 cagcaccttc ttcctgaacg ttctgtccag acaaagagca actatataaa aggatgatga
    14761 agaaaatggt gaacggttta aaagtgaaaa caggccctca attttattta tatgaagaag
    14821 gtggtatttc aaaagtttct gatctcttga aatcatacgg cgcgaaaaga gtactggtca
    14881 cccacggaac ggtatcatgg gaaaaggcgc tacctaaatt agtatttttg aatgacgaaa
    14941 cgattcaatt tttttatcat cgttattctg gagaatgtag ttatgctgaa gccagacgaa
    15001 tagctacaat catcaaaaaa atgaaatcga tttcgtagtt ggcgttggcg gaggaaaact
    15061 gaccgatcta gtgggttata gtgccaatct tgcaagaatc gatttcggag tcatccctac
    15121 tttagctagt aattgtgctc catggacacc tcttgctgtc atgtataagg agaatggaca
    15181 agcagaaggg aaaacagaac acttttacag acaagctgct ttttttataa cagatcccca
    15241 attagtgatt gattcccctg ttccatattt cattgccggg ttagcagata cactagcaaa
    15301 atggtatgaa tctgagctca tcttagaaca agattttttg caagatgaat catttttgaa
    15361 gctagcacaa gatactgcga agatctgcaa agaagagatt ttgaatcatt ctgctaaagc
    15421 aatccaagat atggcacaaa gaaaactgac atcggagttc aaacagcttt cagagattat
    15481 ctttgctgtt gctggtttag ttggaggatt aggagataaa tacgcaagaa atgcggcagc
    15541 acatgctatg catgacgcta tcagtaaata tattccggaa agccatcgtt ttctacatgg
    15601 agaaaaagta gcgtatggga ttttctatca actggcacta gaaggtcgct gggaaaaaat
    15661 agacgagtta tatcctttgt atcgggaatt agaactgccg gtttctctag aacaaatggg
    15721 attatttccg aaagataaac agataataga taaaatggct gaatttattg attcgaaaga
    15781 gaaagtgcat ttgattccta tagaggtaac acagaaatca ctgatacagt caatgatgga
    15841 actggaaggt tatatcagaa agatctgaag gaggaggaca catggaaaca ttaagtgtag
    15901 tacaaagttt gttgattgct ttatgggtag ccgcggttat gtcccgctgg ttaggtggag
    15961 gagccacgtt gaccttacgt ttttctcctt tgatgactgg attagtcgtc gggttgatca
    16021 tgggggaagt tgcacaagcg atgattgtta cagccgcttt gcaaatgatt tatatggggg
    16081 ttttttctcc aggaggatca atgccagctg aaccatctat tgcagcagct atcgcagtac
    16141 cagtcgcatt attaggggat ctgtcgccag aagcagcgat tgccgttgcg gtgccagtcg
    16201 gattgctcgg aagttacttg tatcagtttc gttttttcat caatactttt ttaggtaaat
    16261 atacagacaa agctgtagaa gatttgaata caaaagctat ggcccgatca attattcttt
    16321 atccaacggt tgcctcattt ttattattcg ttccgcttgt tttcattgct ttatatttag
    16381 gggcgccatt gatcgctgat gtaatcaaag ctttagaggg aacagtcgtt atccacattc
    16441 ttgaagtagt aggtggaggg ttagcggcaa tcggtatcgc gacaactgta tacgttatcg
    16501 gtcgaaaaga ttatctggtc tttttcttcc ttgcttattt tatgagtgtt gttttgaaat
    16561 ctttagatat tacgatggtt acttatgcca tttttgggat tattatcgct ttgatctttg
    16621 tccagtcgca aaaagggaaa caagtacagc ctgccacaag caataacaat tcagcatctt
    16681 ttgatgacga agatgactat gatgacggat tttaatttag gaggaatggg aaatggctga
    16741 aataatggat aatcaaacag gtgctcctga agaaatcacg aaaaaagatg taacaaaagc
    16801 ctatctgaga tggcattttg caaacgaaat tcctcactct tttgaacgtt acttggcgcc
    16861 atcactacta tacggaatga tgccaatctt gaaaaaactt tataaagatg aagactcttt
    16921 aaaagcagca tataaacggc agttactgtt cttcaacact caattaagct ggggtggcgg
    16981 tgtgattact ggcctaatgt cttctatgga acagcaaaga gcagaagaag agtatgaaga
    17041 aaaagagatc ttgatgcagg atgacttgat gtataacacg aaagcgggat tgatgggggc
    17101 actagcagga atcggagatg caatcgattc aggaaccgtc caatatattt ttatcgcaat
    17161 cgcggtacct tgggcacaac agggaagtcc tttaggcgca ctttttcctt ttatctgctt
    17221 tgggttgtat caggttttac taggggtatt tttcgcaaga caagctttca ctatgggccg
    17281 taatgctaca ggcctaatgc aaaacactgg tgttcagaca gcgattgaaa tgctatcagt
    17341 tttagggttg tttatgatgg gggtgcttgc gggaaactat gtaaaagtag aatcttcatt
    17401 gaaatttgcg atatccggac gtgagtttgt tatccaggaa attcttgatc aaatcgtgcc
    17461 agggatatta cctttagctg tcgtaatggg tgtgtacttg ttctatacga aaaaaggatt
    17521 gaaagtcaca caagcattat tatggctgac tggaatatta attgtgctag caggaatcgg
    17581 tattttataa aaagaaggga acgtgaataa gatgggtgta gtcaatttag cgcgtgtgga
    17641 tgagcgtttg atccatgggc aagtaatggt aacgttatct caaaaaagtg gagtgaattc
    17701 catttttgtt gtagacgaag ttgtagcaaa agataaattt atgagagatc tttacaaaaa
    17761 tgcaggaagc cgtacaggac aaaaaacaat tgtcattaca ccagagaaag ctaaattcta
    17821 ttgggatgaa tatcaattta aagaatacaa ttgtattttg atcgcaaaaa cagtccaaac
    17881 gatttacgac ttagtaaaac acggaatccc catggaagaa ttgaatattg gagggattgc
    17941 tcaaaaaaat cctgatacag atcttttagt gacgaaatct gtttatttaa ataaatcaga
    18001 tgctgaaaaa ttgaaagaaa tgaatgaaca atatggcgta aagaatattt attttcaagc
    18061 cactccatct gcacctaaaa caggattaaa agatgtattg aacaagtttg atttgtcata
    18121 aacaaatgct tagaaaaaag ataaagaggg cgaaaaaatg aagaagaacg agctgtttcg
    18181 tgattgggaa tttcgttatc gctatattta ccgtaagcgc cgtacaaaaa agagtaaaca
    18241 gcgttttctt tcagcattag tatcagatat ttacagtatg agaacagatg tgacagtcat
    18301 tgcttacgat acgctagcct accgatcaaa aaatatttat gttggagata tcgaaaaagc
    18361 agagaaagtt atctgtactt attacgatac acccgttcat gcattaggaa gttatttcat
    18421 gtttgattgg aaagaccaaa ggaaaaaaac aatctactct atattattgt ccttcatttt
    18481 gttgttcagt ttaggttggt ggggaatgat gatatataac aaaaatcctc atcacgtatt
    18541 cgatctgcta tccgtataaa caggtatcac tgtactagca tttgggagct actttttctt
    18601 attgggaaaa gcagctcgcg gatggcctag cagacaaact tttattcgaa atacttcatc
    18661 catattaacg atgctagaaa tgatccgtac gattgatgat ccgagtgtag cgtatgcgtt
    18721 tgttgatgaa ggctgttatg gagaaaaggg cttagacagc gtgagatcgg gtatgaaaaa
    18781 agaggctatt cttttttatc tagactctgt tggggcagat acaccgctac agttttcggg
    18841 aaattatttt tcaaataaag aacagtggct gaaacaagtt gataagttga aagaaaaaaa
    18901 cgtcaattat atttttagtg caagaaaaaa gcaagcgcag ttcttctatt tgaccaaaac
    18961 agatttacga gggaaaacat ttaattggca aaatgccaat cagattattg ctctttttcg
    19021 ataagtaaaa agtgcaaaac aaggagtgag aagactaatg ttggaaatca tgatcgttac
    19081 acatggtaag ttgagcgaag gactgaaaga tgcggcggaa gtaattgtcg ggacatcgag
    19141 ccatattgaa acaatgtgct tagagtctgg ggaggacatc caaacattcg gagagaaggt
    19201 caaagaaaaa ttaactatga tcaacacagc agaacccatg ctagtatttg ttgatctaat
    19261 tagcgcaagt ccgtacaatc aagcgctctt ggcagtcaat gaactgactg aagaaaagaa
    19321 agcagccact tatgtcatag ggggcgtgaa tctgccaatg ttgttagaag caatcaatca
    19381 tcagatgctt cacacaccga tagaagaagc ggtggaacaa attgtcaaac aaggaaaaga
    19441 taatttaact gtttggcatg cttcagcgga agaaaaaaaa ttagatgagg acgattttta
    19501 gaaggaaggc tgaaaagatg aagtggggat ttagatggta tggtgaaaaa ggggattcga
    19561 tcccattaaa atatgttcgc caaataccgg gaataaatgg gataattgga actttgctga
    19621 ctaaaatgcc tggagatgtt tgggagattt cagaaattga ggagttgaaa gcatctgttg
    19681 agagccaagg actggaactg cttggaattg aaagtgtagc gatccacgat gcaatcaagg
    19741 cagggacaga tgaacgagat tactatattg ataactatat acgaacaatc aaaaacttgt
    19801 ctcgatgtgg ggttcgattg atttgttata gcttcaaacc aatttttgga tgggcgaaaa
    19861 ctgatttgtt taatgaaaac aacgatggaa gctattctct tttatacgat cagaaaatcg
    19921 tcgatcagat ggagccagga gaaatgtatc aattgataca cagccagtca aagggattca
    19981 aattgccggg ttgggaagaa gaacggttga aaaaattcgc tcagctggaa aaactgtatg
    20041 aaggaatgac cgaagaagaa ttatttgaaa atctgactta ttttttagaa aaagtgattc
    20101 cagtgtgcga aaaagcagat gtaaaaatgg ctatccatcc agatgatccg ccatgggaac
    20161 tttttggttt tcctagagtg acgaaaaatc ttggcgactt gaagaaaatt ctaaatgcag
    20221 tagattctcc atataatgga ctaacgctgt gcacaggatc tttaggggca aatccggaaa
    20281 acgatttagt tgaaatcatc catgaggtag gttcgcgcat ccattttgtc cacttcagaa
    20341 acgtggagtt tttaggagaa agaaagttca aagaaacggc acatccctct acagaaggct
    20401 cccttgatat gtatcatatt atgaaagcgt tggtgcaaga agggttcgac ggtcctatac
    20461 gccctgatca tggtagaacc gtgtggggtg aagtggctat gcctggatat ggcctgtatg
    20521 atcgtgcaat gggactcact tacatgcaag gtctatatga ggcgataagt aaggaaaaac
    20581 cactgggaga gcattatgaa taaaatcaag ctcttcatct ttgatatgga tggcctttta
    20641 ttagaaactg gacgtttagc ttatcgtgct tatgtaaaat cagcacaaaa gtatgattat
    20701 gaaatgcgta aggaagtcta ttatttacta actggccaaa cagaaatggc gataagagaa
    20761 caaatgggca ttttgtacgg agaagatgtt ccatatatca aatggcgaga agcaatcaat
    20821 caatataaag aaaaaatcgt gaaagaagat aagagagtat atacgaaaaa aggagcagaa
    20881 gaaattttat cttttgcaaa agaaagagga atccatacaa tcgtggcttc gtctaataca
    20941 cgggtaaaag tagaaatgta tttaaaaatg gaaaatctat atgccttgtt tgatcaaatc
    21001 atttcagggg atgatgtaaa aaaaggaaag ccggaaccag agatcttttt gaaagcttgt
    21061 tcaaaaatga atattcctcc aagtgaagca cttgtatttg aagactcgat tgcagggatc
    21121 gaagcagcaa ggcgagcggg cattttgtct tttctcatca aagatcattt gatagggttg
    21181 cccgatcata atgggaagca taagttgaaa gtagatgtaa gtttatatga atccaataaa
    21241 gcagactatg aattttatga cctgcatcaa gcaaaacgat ttttagaaag taaagggttg
    21301 tatctctaat aaagaggact attttctagt cctctttatt tattgtcctg cacgactgag
    21361 ggaacagatg aaaaagaagt aattttttat tttgaagtat ctaccttatt tgtagtgaac
    21421 aatttagaac aaacacaaaa cgcatctact gttatctacc agtagatgcg tttaaagaga
    21481 agaacgagaa tcgtccatat gagggtttcc actccttatg cagatttttt taattcttgc
    21541 actgcttgtt cgatcgtaac acctgtcgct acatgattgg tattttcttt gtcaaaaacg
    21601 acaaatagat tcaaatctgt atccaaggtt actcgatatt gtatatcttt gttatagaat
    21661 gtcatagcca ttctcctttc tttaaatact tgctgaaagg caacgaacgc gttgataacg
    21721 aaattccatt tataagtata ccaccaattg aaaggttttc atagttaaga aattttaaag
    21781 tcaaaagttg cagataaaag caaataaaca agaaaacaaa aagtgaatca atcgcggtta
    21841 ttcaactttt tcttcgattc gaagacaata gaagacaatg aattttatat ttcattgcat
    21901 tatccttgtg ttattagaaa aagcatgata tattaaatga gtaatctatt ttgaaacgta
    21961 atttgagcga tatatctaca tagataaaac tccttttgcc tatcaaatat ttattgcaac
    22021 gaaaaaacgt acattgatac gtatcaggag gaatttattt atgaataacg gtacagtaaa
    22081 atggttcaac gcagacaaag gttttggctt tatcactggt gaagatggaa atgatgtatt
    22141 tgcacatttt tcagctatcc aaggtgacgg cttcaaaact ttagaagaag gccaagcagt
    22201 gtcttacgat gttgaagatg gtcaacgtgg ccctcaagca acaaacattg ttaaagctta
    22261 ataaaaattg acttttaacc gtcttttcga aagaaaagac ggtttttttg tacgaaaaaa
    22321 tt
//
LOCUS       DBBGSZ010000040        21254 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.041, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000040 DBBGSZ010000000
VERSION     DBBGSZ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21254
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.041"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(177..758)
                     /locus_tag="ACIZE5_002161"
     CDS             complement(177..758)
                     /locus_tag="ACIZE5_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ReoY family proteolytic degradation factor"
                     /protein_id="HGC6109277.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(764..2023)
                     /locus_tag="ACIZE5_002162"
     CDS             complement(764..2023)
                     /locus_tag="ACIZE5_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGC6109278.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(2025..3071)
                     /locus_tag="ACIZE5_002163"
     CDS             complement(2025..3071)
                     /locus_tag="ACIZE5_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109279.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(3306..3581)
                     /locus_tag="ACIZE5_002164"
     CDS             complement(3306..3581)
                     /locus_tag="ACIZE5_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HGC6109280.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(3824..5134)
                     /gene="der"
                     /locus_tag="ACIZE5_002165"
     CDS             complement(3824..5134)
                     /gene="der"
                     /locus_tag="ACIZE5_002165"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HGC6109281.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(5316..6545)
                     /gene="rpsA"
                     /locus_tag="ACIZE5_002166"
     CDS             complement(5316..6545)
                     /gene="rpsA"
                     /locus_tag="ACIZE5_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HGC6109282.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(6680..7360)
                     /gene="cmk"
                     /locus_tag="ACIZE5_002167"
     CDS             complement(6680..7360)
                     /gene="cmk"
                     /locus_tag="ACIZE5_002167"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HGC6109283.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(7409..8044)
                     /locus_tag="ACIZE5_002168"
     CDS             complement(7409..8044)
                     /locus_tag="ACIZE5_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HGC6109284.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(8110..9513)
                     /locus_tag="ACIZE5_002169"
     CDS             complement(8110..9513)
                     /locus_tag="ACIZE5_002169"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HGC6109285.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(9500..10531)
                     /locus_tag="ACIZE5_002170"
     CDS             complement(9500..10531)
                     /locus_tag="ACIZE5_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6109286.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            10562..10783
                     /locus_tag="ACIZE5_002171"
     CDS             10562..10783
                     /locus_tag="ACIZE5_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HGC6109287.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(10948..11685)
                     /locus_tag="ACIZE5_002172"
     CDS             complement(10948..11685)
                     /locus_tag="ACIZE5_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HGC6109288.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(11838..13178)
                     /locus_tag="ACIZE5_002173"
     CDS             complement(11838..13178)
                     /locus_tag="ACIZE5_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGC6109289.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(13415..14938)
                     /locus_tag="ACIZE5_002174"
     CDS             complement(13415..14938)
                     /locus_tag="ACIZE5_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HGC6109290.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(15316..15927)
                     /locus_tag="ACIZE5_002175"
     CDS             complement(15316..15927)
                     /locus_tag="ACIZE5_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGC6109291.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(16050..16175)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(16257..16973)
                     /locus_tag="ACIZE5_002176"
     CDS             complement(16257..16973)
                     /locus_tag="ACIZE5_002176"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGC6109292.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(16979..17548)
                     /gene="scpB"
                     /locus_tag="ACIZE5_002177"
     CDS             complement(16979..17548)
                     /gene="scpB"
                     /locus_tag="ACIZE5_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HGC6109293.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(17532..18302)
                     /locus_tag="ACIZE5_002178"
     CDS             complement(17532..18302)
                     /locus_tag="ACIZE5_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HGC6109294.1"
                     /translation="MNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDIPIATITEQY
                     MNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEEDPREELVTQ
                     LLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKKIDLIRAMQK
                     ILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESPSKSEVVTTF
                     MALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(18299..18670)
                     /locus_tag="ACIZE5_002179"
     CDS             complement(18299..18670)
                     /locus_tag="ACIZE5_002179"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6109295.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(18689..19576)
                     /gene="xerD"
                     /locus_tag="ACIZE5_002180"
     CDS             complement(18689..19576)
                     /gene="xerD"
                     /locus_tag="ACIZE5_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HGC6109296.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(19672..20145)
                     /locus_tag="ACIZE5_002181"
     CDS             complement(19672..20145)
                     /locus_tag="ACIZE5_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HGC6109297.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(20250..21113)
                     /locus_tag="ACIZE5_002182"
     CDS             complement(20250..21113)
                     /locus_tag="ACIZE5_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor B family protein"
                     /protein_id="HGC6109298.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
BASE COUNT         6003 a         4541 c         3557 g         7153 t
ORIGIN      
        1 aaaaagcttt cctttcaatc atcaatgtgc atgaagtgga agggcaaggc tttacttatt
       61 tgaagccaca gacaagatta ctgaaaaaac tataagaaaa aagacaaaga taggctatga
      121 ggaaagattc cacatccagc tgacctttgt cttttttagt actatactat ttttaactaa
      181 ttgttatgtt cacttacccg gttacttttc ttttgtgtct gcaaaaggat ctttcggtta
      241 acttcatcag ataatttcaa aaaagcatcc ctatctccat cttctagtgc ttgatcgatt
      301 tgagcataaa gcatttttag ttttgcctct tcttcttttt cttgaaaata tcgttcaatt
      361 aattcagtat cttcttcact gactgaagaa tcccaagaag aaaatggatt gtcttctaag
      421 atagatagat attctcttgt ctgccaagca ttttcgaata tacattccac atataaaggc
      481 tttttccaat tcaaacggat ttcatgaaaa atctggtctg tgtccgtaaa ttcttttccc
      541 tgcaaaaaca atttcatggg ttccccttca acagatagat cactgatctg cagtcctcga
      601 tccgcaaaat tcgccccttc aacaaagtgg acattgctta aaatcgcttc atgattggca
      661 agataattca agatccaaaa aacttctctt cggctaaaag atacatgatt gaccatccac
      721 gttaaaaaat tcttcttttc ccgtacatca attagcattt ttctcacctc tctgttaggt
      781 catctaataa tgacagtgcc tccatatctc ctggttcaag tgttaaataa taagtcaata
      841 attcttgcgc tcttttcagc tgcccttctt ctcttaagaa aaaggcatac tctttcaaga
      901 aatctggttc atgtgatagt tcatgataag cctgttcata gtgtacagct gcaacggtaa
      961 agtcttctaa ttcattataa gcatgggcta ggttccattc tgcataagga ttagcagttt
     1021 cttccatctg attgatcact tgtatcacat cttcatatct ttcatcatcc aagtaaagat
     1081 tacttaaagt aagtaatgtt tcatcttgtt tgtctcctac ttctaaagct ttcagtaaaa
     1141 gttcttctgc tcgctgtcta tcatgcagac ggaaagcatt ttccgaggcc aggtgataaa
     1201 gttcgacttg gtaaggattt tctttgattc cttcttctaa cactgtttgt gcttcttcaa
     1261 tcatttcttc ttcttgaaga gcttgtccta gatatagata taacgattga taatgcggat
     1321 taacttctcg aagttcttcc agatagttga ttgcctgctg attttctttc aattgaagat
     1381 tcgtaaaagc tagctggaac agtcgatcat ctgtcctttc ttctttcagt gcttcttcta
     1441 aaggtacgat agctgcttcg aattctcctt gcatacttaa ggattgtcct aaacgttcct
     1501 gcatcgagat tcctgaaatt tcatttatcc cgcttgccaa caatgtttca taaaccactg
     1561 ctgcctcttt gaaacgatca actgaaaaat acaattcagc tagcgcaaac tggatcaatg
     1621 gttcatcagg aagcaaccca gctgcttctt tcaattttgc ttcactcact tcagggattc
     1681 cgataacttg gtacaaatca gctatcgcca ataagctttg cggatagtaa tcactttgct
     1741 tatccacttt ttccaggtat tcaaaagcta agtcgatctc attatcttcg attgcaattt
     1801 ctgctaacgg gatgttcagt ccgtcatttt ctgggtattg gttgatcagt tgttcaaaaa
     1861 tctgttttgc ttcgatcaaa aagccaatag ccagcaattc ttcgcctagt tcagctaata
     1921 tatctgctgg gtcttctttt aatgcttttt ctaaaaagat ttgtgcttgt gacaagtctt
     1981 catctgataa agcttgcaac attttttcgc tatttgtatt catttcaatt ccctcttatc
     2041 tcactgacga tttgttgaaa taccgtcatt gttctcaata attctttttc gtttggatgt
     2101 tggtatccgt ctattatacc tattttttct aaaacaagta tttttttgct tttttctgcc
     2161 aaaaaaagaa ctttttccaa atactccatc tttgaaatct gttccagcca gtggattgga
     2221 tagccaagca agtccagcca cacaaaaaag ttttttagtt ggaaatcaaa aggatatgct
     2281 tggagattcc acacgaaatg aaacatcatt cctaaaaatt ttttcatact agcagaaagt
     2341 agatggccat tttcggtcag ataaaaagct tgttcaaaca gtttaccata atttgacagg
     2401 ttttctgcct ctaattgata aaaatagatc atttcttcga tcatcccggc aaacggccga
     2461 gtcgttaatt gctttttatt tggatagttt ttatacagat tttgcaaaaa acgatgatca
     2521 caaatcattc cgcaacagat aaaagtcaaa aagtcaatct gctttccgtc cacctgccgc
     2581 tcgctgattg tttgatcata aacgatgcgt tctggcagat tgatggtttg cagcactaca
     2641 cgatttggta gctgcaaaat cgtccgctgc ggtgttaatg ctcggcttag agaacggatc
     2701 gatacaggga tcatccatag tgatgaatca agggttgtat gtttttgaaa aaaacctgcc
     2761 agatccatga tcccttcatt tccaaatccg atgataaaca tggattgatt ttcgggatag
     2821 cgtttgacga aatcaagcag gttctttaat tctgttaaat gattgcattg agtgttggca
     2881 caaatatacc agtcattgtt tgcttgattt gcaaataacg ggttgatctt atctgcaaac
     2941 aaatcataat agcgctgatt cgttaaaaat aagattggct gatcaatgga aagttctctt
     3001 agctgactga ctagcgtttc tccgtaaaac actttcgtca acgcatcttc tacttgataa
     3061 tcaagttcca tacgcatccc tcctcttctt atttttattt taccattagt aagcaaattc
     3121 tagaaaagat aagagcaaag ctcacctcat aacttgcaaa taaataaaaa ttaaataaaa
     3181 tacatgtgtt ttctatgtat gacatacgga ttcggaatct ctgtctctta tttattcctt
     3241 ttctgctagg aaataaaaag aaaagcactt gtagccctag agccacaagc gctttttcaa
     3301 ctgtcttatt taacagcgtc ttttaatgct ttacctggtt tgaatgcagg tactttgcta
     3361 gctggaattt cgatttcttc accagtttgt gggttacgac ctttgcgagc tgcgcgttcg
     3421 cgaacttcaa agttaccaaa accgattaat tgaacttttt cgccgttagc taaagcatct
     3481 tgaatagttg aaaatacagc atctactgct gcagttgcat cttttttagt taaatcagta
     3541 gctgaagcaa ctttttcgat taattctgct ttgtttgcca tggatagatt cacctcctcc
     3601 acaagagata tgatagaaat atcatttagt taaaactttc tgagtggtcc agaagtttaa
     3661 aaagaaatat tgattaactt caatattctg ttatcacgat atcatatgaa ccgcttaata
     3721 gcaaggtttt taccaatttt cacatgcttt ttttagtcat agaaacgtaa caaacgaaac
     3781 tgtctttttc ttttgaaaaa aaaacgtcga tatggtaaaa tgcctatttt ctcctacgag
     3841 ggataattcg gatggacgtc ccttcaaaag taaatgcttt tctgatttga ttttctaaga
     3901 aacgttcata agaaaaatgc atcaattcct cttcattgac aaaaacgaca aatgtaggtg
     3961 gtttgacagc gacttgtgta gcataaaaaa tcttcaggcg ttttccttta tctgttggtg
     4021 ttggattgat tgctacagca tccataatga tatcattcaa cacagccgaa gagatacgaa
     4081 gattctggtt catacttact tgttcgatca tttcaggcag acgttccaac cgttgtttag
     4141 tcactgcaga aacaaaaacg attggagcgt aatcaagata ccggaattca tcacgaatct
     4201 cttgttcgaa atcacgcatt gtattggttt ctttctttac aagatcccat ttattcacga
     4261 cgataataat tccacgacca gcttcatggg cgtaacccgc tactcgcttg tcttgttccc
     4321 gaatcccttc ttcagcattc agtaccatca aaacgatatc agaacggtca atggcacgca
     4381 ttgcacgcat cacgctgtat ttttcagtat tttcgtatac ttttccgcgt ttacgcatac
     4441 cagctgtatc tatcattaag aatttctgac cactttcaga aacgaagtgg gtgtcgattg
     4501 cgtctcgggt cgttccttca atatccgaaa caattacacg ttcttctcct aaaatcgcat
     4561 tgatcaaaga ggatttacca acatttgggc gaccaatcaa actaaactta atcgtgtcgt
     4621 cgtcctcttc ttcagtctct tcagagaaat acttcactgc ttcatctaaa atatcaccaa
     4681 tccctagtcc atggcttcct gaaacaggat aaggatcgcc tagccctaag gaataaaatt
     4741 catagatatc gtttctcatt tctggattat ctactttatt gactgctaaa atcactggtt
     4801 tattacttct gtataaaatt ttcgcaacca tctcatctgc gtctgtcacg ccttcgcgtc
     4861 cgctgactac acaaatgatt acatctgctt cttcaatcgc gatttctgct tgatgcttga
     4921 tctgatccat aaaaggttca tcgccaagat caattccgcc tgtgtcgatc acgctgaatt
     4981 ctcgacctaa ccattcacct tttgcataaa tacgatcacg agttactcca ggagtatctt
     5041 cgacaatcga gatacgctca ccagcgatgc ggttaaaaat cgtagactta ccgacgttcg
     5101 ggcggccaac gattgcaatt gttggatttg ccatattatt tcctcctcac aagtttccaa
     5161 tctcacttag tttaacgaat gcattgccaa ctttcaagca tagattgtca attaaacgaa
     5221 gtatttttat tccttattga aatactaatc gcttttcaaa agaaaaactg agacaaaagc
     5281 agctgctttc atctcagtca cagatacaaa atcaattatt tttcagaatc atcggttgct
     5341 ttttcttcta cttcttcttt caacgcatca cctaaaatgt ctcccatagt aaatccagta
     5401 ttttcttctg gtaattcata agactcaaca ttttttggtt cttcttctga agctggtttt
     5461 tcttctaaag ctttgatact caatgcaata cgatgttctt ctggatggat ctctaatact
     5521 ttcactttca cttcgtcacc ttcatgaagc acttcatgtg gtgtcgcaat atgtttatgt
     5581 gaaatttgag agatatggac tagcccttct actccaggga acacttcaac aaaggcaccg
     5641 aagcttgtca aacgtttaac tgttccgtct aatactgtgc caactggagc ttttgtatcg
     5701 atttctgacc aaggtccagg ctgtgtgtct ttgattgaca aggaaacacg ttcttgttca
     5761 ggattgatag acaacacttt gacatttaca tcatcattga cagccaatac atcacttggt
     5821 tttgctacat gactatgtga aatctctgag acatggacta gaccgtcaat tccgcctagg
     5881 tcgacaaatg cgccaaaatc agtaagacgt gcaacacgtc cactgagaac atctccctca
     5941 tggatagttg aaagaatttc ttttttcttt tcttctcttt cgttttccac taccgcttta
     6001 tgcgataaga tcaaacgatt ttctgatggt tcgatttcga tgattttaaa gctcaatgtt
     6061 ttgcctttat agtctgaaaa gtctgcaaca aaatgatctt ccaccattga tgcagggaca
     6121 aaaccacgta caccgacgtc aacgactaaa ccgcctttga caacatttgt aacaggtgct
     6181 tcgatgacct tgccctcttg gaaatctctt tcgatatctt cccaaacttt tttagcatct
     6241 aaacggcgtt ttgaaagtag atagctgccg ttttctttat ctttgccgat cgtactgata
     6301 acgactaaat ctaatacatc accgactttt actacttcgc tgatatcttc taccggcaaa
     6361 gttgataatt cttttgccgg aacgactcct tcaactccag ccccttcgat tccgacaatc
     6421 acttgtttgt cttcaatgac taaaacttcg cccttaacaa catcgccaac ttttacttct
     6481 tgtacgcttt tcattgcgtc ttccattgac tggttgttct cttgattttg atcaaattct
     6541 gtcataacac ttgtcctcct aaccaacatt ctgccgtaag tacggtactg tttttagttt
     6601 aattgattat tcaaaaaaaa taaagcgatt tcgttcgttt tccttgaaaa aacaattgtt
     6661 tttcattttt tttcttaatt taaaaaagaa gataaccttt tttcaaaaca acagctttta
     6721 ttgctgcaac gacttctgga atcgatttgc cagtcgtatc gatacgaaca gcatcctctg
     6781 cttgcttcag cggagagacg tcccttgttg aatcataatg gtctctttcc tgtatctctt
     6841 tcgtcagtgt ttcaagatca gtcggaattc ctttttcttg gttctctttg aaacgtcttt
     6901 ctgcacgctc acttacgctt gctactaaaa agattttcac ttctgcattc ggtaatacag
     6961 ctgtcccgat gtctcttccg tccatgacaa cgccaccgcg ttcccctatt tttcgttgga
     7021 cagcaactaa ttcttctctg acttttccat gtgcagagac ttcagaaaca gcttttgtga
     7081 catctggttg acggatttct aaagtcacat cttttgatgc tatgaataca tgctgtccat
     7141 cttcttgttg cgaaaaagag ataggatact ttttgatcag cgaaactagc ccttcttcat
     7201 ctgaaaaaga tacattgttc gtaatagcta aataagttac tgcgcgatac atggcaccgg
     7261 tatctgtata aatataattc aattcttttg ctaatatctt ggcaacggta cttttcccag
     7321 atgaagcagg cccgtcgatt gcaatactga tttgtgtcat gatataactc ctttttctca
     7381 gaaaaaaagc cgcaaagcgc ggctattatt atttaattct taattcttga ccagggtaaa
     7441 gcataaagtt gtttggatct aagccattca attcaaacaa ttgatcagtg gtgatccctg
     7501 cacgctcagc cacttgtttt ggaccttcgc ctgcttgaac agtcgttgtt gaaccggctg
     7561 cagctgatga agaaggtgtt gtttctgctg cattgctgct tgaatcccct gcttgataag
     7621 ttgcctcact tgaggaagtc ggtgttgtct ctgctgcaat actgctttct gacgttacac
     7681 ctgtatcttg agacacagta gattcttccg cgattgtact agattctact gttgaagtct
     7741 cagttgactc ctcttttgtt gtacttgtag aactttctac tactgatgtc gaagtttcag
     7801 aagaagttgc tgctgttgca ttgttgcttg atccatttct gatccagaaa taagcacctg
     7861 ctggaatagc gatacataag accagtaaaa tcaaaaatag cgaaagaaat aatgtatttc
     7921 ctttcttttg ttgtctctga gaacttcttg atgaaacttc atcatctgta tcgtagattg
     7981 gttgttccca tggttcttgt gtttcgttat tttctgtaga ttgatgtcta tcttttctgc
     8041 tcactgtttt acctcctaaa ctctatcgtg tgtattatac cataggaaaa agtgtcttgt
     8101 cctaaaaaat caatgttcca tgtttttttt aaataaattt agtaaaatcg ttccccaatg
     8161 aagttgttca gtcttagaaa aaagcttcct ctttggcaga agttctgctt ttgctccatc
     8221 aatatcacaa caattctgcg gcttttcgga gagtttttcg ccaaaataag ctaagatgaa
     8281 ttttctgcgg cagttttctt cattaatata gcgaagcatc tgctgcaggc ggaattcttt
     8341 ttctttttcc tgacgtttga gccgttccac ccaattttct ggtttttcag actgctggat
     8401 cagctccatc catttttttt gcagctcatc aaagggagct tgctctgtgg catattccaa
     8461 ataaagctca aaactttgtc gctgttctct agaaagttga ttaaagaaat aatggatacg
     8521 ttcatcccca ctttgataaa aaagaattgc tgcactttct tcctgatctc tgcctgctcg
     8581 accgatttct tgtacatagt tttctagact gtctggcaaa tcataatgga ccacataacg
     8641 gatatcagat ttatcgatcc ccataccaaa tgcattcgta gcaatgagaa actgcagctg
     8701 attttttaca aactgctgtt gaagttgtct tctttgagct gcatcaagac caccgtgata
     8761 gtatccaact gtaaaacgtt ccctgaataa atgatacaat cgttcgactt ctttttttgt
     8821 tgcacaataa atgattgccg ctccttgtgc tctttccatg aagtgttcaa gttcttgttc
     8881 tttttgctgc gttttccgaa caaaaagcga gatattttgc cgattgactg attgtctgat
     8941 ctcttttggt ggtcgatcaa atagtacatg acgtatatct cttgctacta aatctgttgc
     9001 tgtcgccgtt agtgccagtg tgaccgggtt tcctaaaagc tttcggattt ttcctaactg
     9061 ttgatattct ggacggaaat caactcccca ttgagacacg caatgagcct catctactac
     9121 atataacgca atattttgtt ttttcagatg ctctaaaaga gaaggattag tcaacatttc
     9181 gggactcaaa aacaaaaatt tatattgcga tagatgacgg aggacgtatc ttctttcaga
     9241 ttgcgaaagt aaactattga aagcagctac tcgtttctcc cctcgttttt gtaattgcgt
     9301 cacttgatct tccattagag aaagcagcgg tgacacgatg atgaccagac cttccattaa
     9361 ataccccgtc aattgatagc aaaggctttt tcccgttcct gtaggcaaaa tagcgagagt
     9421 atcttctcca tcaagcaacg cctgaataat ttcttcttgg ccgggacgaa atgaatcaaa
     9481 tccaaaatat ttttttaatt catttattaa cattctgtat cgcttccttt ctcaatagat
     9541 agatttgata caaacgaaat tctccataat ctaattgtcc atctacattc cattcgctaa
     9601 agcgccactc tcgcacggaa tccttatttg gttccaaacg ttcgattgtt tctgcagaga
     9661 gaatccactc gtatggaaaa tcatcaaaaa acaaggccca ctcaataaga tgatctgtta
     9721 ctgttcctct ttttaaatga cggattgcca tgatctggtc aattgtctga ccattcataa
     9781 acatctgctt ggtgatcatc atgctttgat tgaaattttg ctgtaataat gaatcgatca
     9841 aagcgtgcca aagcgaatct ggccgttttt cgatttgtgc taacaaaagg tggatacatc
     9901 tgctttgttg cagataaacc gctgactcat cattgttttt tgccagctga taaggaagca
     9961 gccctgttcg ctcatttcca gataattggt tagctaaaaa atctgctgct tcttctggta
    10021 tctccgaaaa cagctgcacc aaactctcat acgcagtatc aatcaaaatt tcacgtggca
    10081 attggctttc actaagccat ttttttagtt ggaaagtata aaaaggactt gtctctgctg
    10141 gaagatagtc ttgaataccc gttgccagat tagaaattac ttgaacagca aatttaatga
    10201 gccgccaact agtttcccct gttctgccat agcggtcaaa acgcaaacca gtatgttcta
    10261 tttgatgttc ggacaacata tcagcccctg caggcgttag ctttgcttca ttttcattta
    10321 tttcgatcca accttgctgc gcaatttttt gcaaaatttg ataaaactta tcctgcttca
    10381 attctggaaa actgttatgg ataaacaaaa gttcgtgggt aaatccataa ataagtactg
    10441 aagtcgttcg ttttcccaca aggagttggt aaagagaact aatccgcagc ttgtgtcctg
    10501 atgaaaatag cgataaaata aaaacaatca tattattctc cttaagttag gatggttaga
    10561 aatgtcacta ctatgtaaac ttgtacctga acgctgtatt gcatgcggtc tttgtcaaat
    10621 cgaagcgcca gatattttcg attatgatga agaaggaatc gttttatttg cccaagaacc
    10681 agaggctcat caacagttcg tgatgccgga agaagaaaca tatgtaaaaa aagcgtatca
    10741 aaaatgtcca gttcgagcga ttttattaga aaataaaata taaatataaa cgaaacttta
    10801 aaaacgtaca ctaagttctc taaacttgaa aataagccgg gatctgtttc tcttgttccg
    10861 tgaaatcccg acttattttg aaagattcat ttgctatcta tagttaattg actagttttt
    10921 tcacggaccc tataggaccc atttatatta tttcaacttt ttcagccagt tttccaatgt
    10981 attgacgatc acagtttgct ggtctgcgtt agaaatttct gcctctccat ctcctttttg
    11041 ctcaccatag ctgccaaaac ctccatgatt tccgccattg attgatacat actctgttct
    11101 ttccggtaaa tactgcttag cttcttgata agcttcctga ttcaatactt tatcttttgt
    11161 cgccgtgatc gataaaacag gaacagctga ttctgtcaat gttccttttt tgtcgggata
    11221 acttgccatg aagaataccc cttttaaatg tttgtctgaa tgattcttat tgacataacg
    11281 acttgccatt acgccaccta atgaatggcc accgatcaca taatcggaat ttggaaaatc
    11341 ttctttgacc ttatccgctt tgtttccgcc catcactgct agatcaagtg gcattttgac
    11401 aatagcgact gaaaagccgt tttttgctaa atcttgcgcc caaatactat aactttctgg
    11461 ctctacgaga gcaccaggat aaaaaataag taatggagac tttccatgat tctttttctc
    11521 tccttcaaaa aataagtaat cttctttgtt ttttccttct tttaccaaca cttgcgcttc
    11581 tgacgatggt tcgtacgtat tttgctgtat atagtaataa ccggctccac cgagtaatcc
    11641 taaaatgatg actaagccaa ttagtattcg tctaaatatt ttcactttct cccacctttt
    11701 ctatctgagt gacccctttt tcttaatcaa gtatgattat accttaaaaa aataagagag
    11761 aaatgcaaac tttccagcat caaataaaaa aagacggaat atccatttga atatccgccc
    11821 tttttgtatg tttattttta tttagcacat aaacgataca cagcttctgc ataaatttcc
    11881 attgctttat acatactact taattcccat cgttcattcg cctggtgcat aaagtcagga
    11941 gtatcaggga acatcgcacc gaatgccaca cactggttca tcgtacgagc aaaagtagcg
    12001 ccgcctgata caaacggttc agtcatgtct ccagtaatat cgcgatatgt ccccaataga
    12061 tttttcacta actcactgtc tagtggcacg tataatgaat caaggaagtc aaattcttca
    12121 taagtcaacc catatttttc tgctgtttta gttaatttag ctactaaatc atctttcttg
    12181 aatgtaacag ggattctcat atctacaccg atttttgttt gttctggtgt gatttccaaa
    12241 cttgcaaagt tcatcgttag ctcgccggat tgttcatctt ctgttttgcc cacgacagct
    12301 tcaccagttg cattttcttg aactaatttt cctaagaaat tgattgggcc aaaatcaaat
    12361 acttctgaaa gagcaattgc cagacgagaa atagcattca ctccttgtgc tgcatctttc
    12421 gcgtggatac ttttaccaag aacgacgatg ccttcacctt gttcttcgaa atcgaattcg
    12481 tgttttttca atgcttcttt tacttcagaa agcttttctc cagagtaagg agctgcatca
    12541 ggaacaacat tcaacgctcc tccagctttt acagaaaact cgttcgttcc tggtcctgtc
    12601 aagtaagctt gcaataagcc tttttctgca taaattaaag gaaattcagc atctggcgca
    12661 aatccttgcg taattccttc ttctttttcg ttatattttt ctaaacaacg ccataaattt
    12721 tcttcatctg taccaaagat aaaacgaata cgtgtcttga attccacgcc agcatcaatc
    12781 aaagctttga cggcatacat tgccgcaata gaaggacctt tgtcatcttg ggatccgcga
    12841 ccaactaacc agccgtcttt tatagttgga tcgaatggtt ttgtttccca attattttcg
    12901 tcccctgctg gaacaacgtc catatgacac aagataccga ataattcatc tccagagcca
    12961 atctctgaat aaccgtaata gccttctgga tctttaaatg ttctaaatcc tagcttttca
    13021 ctgatttcca atactttatc caaagcttca atcacttttt taccgaaggg atgtccttgt
    13081 cctgaatctg cttcatctag tacggaagga attcggatca attcgctcaa tgattctaat
    13141 gcttgttcat gatgttgttc tgtcacaaat tttttcatga tattatcctc ctaatatgtt
    13201 aaaaagggtc atgtcaaatt cctccgacac aacctcttct tctcaaataa tgacgtttta
    13261 agcctgctcc atcagcaagc agaatgttct taacaaatga tgaaagaaaa aacactcact
    13321 gaatggagct attgacttat ccacgtgctt atcgatagcc gtttatcggt ttcttcattc
    13381 ttatgataga ccttgtacct gtatttgtct aggtttagaa cattgctgct acacctagga
    13441 tcacacagat ggctacaaat aatatcgcaa ttaatttacc ggtaaatttc caccacactg
    13501 aaacatcgaa acgagcaatt gctacagcac ccattacgat agcagatgtt ggtgtaatta
    13561 agtttactaa accagatgca gattgataag cagtgattac taaatcctta ccgacgccgg
    13621 caaattcacc cataggtccc atgattccca ttgttgcagc agctaagccg gaagttgaag
    13681 gaatcaagaa tgacataggg atatagaaaa taaatgtaat aatgatgaat acacttgaag
    13741 ataatgaact taatccttgt tcgccccaat gtaagatggt gtctgtgatt aatccattgt
    13801 tcataaccac ttggatacca cgagcaacag ctactacgat tgctacaccg atcaaatcag
    13861 aagcaccagc taaaaattca gagacaaatt cagactcttt catgccataa gtgattgcta
    13921 ctacgatgga cattactaag aataacatag taatttctgg gaagtaccag tcacctaatg
    13981 gaagcatgct tttacctaga accgtaccta gtaccggaag gtttgttaac cagtttgtca
    14041 atgattcaaa aatcgtgaaa ttcgcattca aggttgtcca aggaatcaaa ctgatgatca
    14101 tgataccaaa agtaataaag aacaatacat taacatgttt ttgttttttc gtgattactt
    14161 cttgacgacc gattgcttca atatcgaaat gcttcatatc ttctttacgt tggttgtata
    14221 ctaatgattt tgttggatct ttttcgatct ttgatgcata acgatacaca tatacaatag
    14281 aaatagctaa caaaataacg aacatcaaga atcgaagacc aataccttca cccatcgaaa
    14341 tcccaacagc ttgtgaagct acgcctgttg caaaaggatt taccgttgaa gctagacagc
    14401 ctacttgaga ccctactaat acgattgcta cagctactac tgtatcaaag cctacagcca
    14461 tcatgactgg gatcagtaaa gcatagaatg gaatcgtttc ttctgccatt ccgtaagtag
    14521 agccgcctaa tgcaaataac agcatcaata ctggaataag cattttttct tttcctttga
    14581 atttcttcac aactgaagca atcccggcat ctagtgcccc tgttttgttg ataataccta
    14641 aaaatccacc aacaaccaaa atgaagaaag agattgggat tgcagcaggt gtttctttag
    14701 ttagctcccc cgctggtaca cctagcatcc cattgattgg cgccatgaaa atatcccaca
    14761 gcccttgagg attttgttgt actcgttcat atgatccagc gacgatgttg cctgcatcgt
    14821 ctacactata gtgcccagct ggtataaacc aagtaagtac agcgattact gcaataataa
    14881 taaataagac cgtatacgct gaaggcattt gaaatttttt cttttttgtt tgttccatct
    14941 tcttcttcct ttcttttccg ttagagacaa caattttggc tctaatgtta ttttatcaaa
    15001 aagagtatca gaacaaaaat aataacacgc attttgtaaa acttttgttc aaaaagttcg
    15061 tttttcccta ttccctcctc ttttttcagg tttttaaagc tttcttcttt ttcattgtag
    15121 cgtttccttt tttttataaa caaacatttt cgtcttttaa aaggagaaga atttcacatt
    15181 tgcaaagaat tgattgattt ttatgcataa atcaaaaaaa tactcaaaac aaacaaataa
    15241 aacgtttaca ttattgcatg tcttgtattt ttttccaaaa aaaaagacca agaaatttct
    15301 tgatcttttt gatatttatt tgactgctgt atgacgttgt tcgaactgat gttgttttcg
    15361 acttaaccat ggaagaagtt gcgcatgcag cactaaaaag acagcactca cgatgaatcc
    15421 tttgatcaag ttgaaaggaa cgatcccaat cagtacatag tttgctaaag acatgcccag
    15481 catctgtgtt gcgttcagcc ctaaaaacat taagtaaaga ggcgtaataa cgaaataatt
    15541 tgcgatactc ataaaaatag ttagagcgat ggttcctgta atgacaccta aaaatttgtt
    15601 tcttccttta tgctgtttct ttacactaaa gaaataataa atcgggaatg taaagatcgt
    15661 tgttgataag aaactagcag tgtctcctac caaattatcc ggagaaaaac ctgtagtcag
    15721 cagatgtaat actgaacgca agaacgctgt tgcaactccg gccgctggac cgaataagaa
    15781 catgctgatc aataccgaga tatcactaaa atcgatcttc aaaaaactaa aagccggcat
    15841 gatcggaaaa gcaaaatact gtaaaactaa tgcgatcgca gcaaacatcg ctactgcaac
    15901 cattttctgt acacgggtgt tcttcatttg aaatcctcct gttaggactc ctcttcagcg
    15961 aactttttga cgtttctctc caaatgaaaa aactctattt tccagggaaa atagagttag
    16021 agttatttga tcaagcgtcg tcaaataagc tctatcttct ttatccagac tatactgtcg
    16081 gtatcggaat ttcaccgatt cagctatttt tttgcaaaat aggtcgtgga ctataaccac
    16141 cggtcgggaa tttcaccctg cccctgaaga cgaaccttat ataatttttg tttacatatt
    16201 cattatacat atctattcaa aaaacgcaac atctaacact tataaaaagt aagtgttcat
    16261 tttgagtggt tcagcaaact gctgacttct tttttgttca gttcacggta atccccagga
    16321 cgtaggcctt gtaaagtcag atctccgtat ttttcacgtt ttagtttttg cacaggaaga
    16381 ccaactgctt gaagcatatt tttcacttga tgattacgtc cttcgtggat cgtcaattcc
    16441 acgatactgt ggtttgtctt aggatccact gataaaattt ggaatttagc tggagatgtt
    16501 tttcgtcctt cgatctttat tccttttgtc aaaggtgcaa gcatcgattt tgtagcgatc
    16561 ccttttacct ttgcaacgta aactttatcc acttcatgtt ttggatgtgt caggcgctga
    16621 gcaaaatctc catcatttgt cagtagcaag atccccgaag tatcgtaatc cagtcgacct
    16681 acaggataga tacgttcttt taccatcggc aaaagatccg taacaacttt tcttcctttg
    16741 tcatctgcaa cagcagaaat aactccttta ggtttgtaca ataaatagta accgtattct
    16801 tcttgataaa ttgggacttc atccacttcc acagtgtcat gtttcccaac ttttatccct
    16861 aattccctta caacttgtcc gtttactttt acacgtcctg caaggatgaa ttcttctgct
    16921 tttcgacgag aagtgatgcc agcgtgggca attactttct gcaatctctc cattacaatt
    16981 attctccttt attcattcca tcaaagaata gatctggtga cacgtcttct tcaagtgaaa
    17041 tttccatttc ttgtgtatca ggcagttctt ctaatgattt caaaccaaaa taatctaaga
    17101 agtagccagt tgttccatat aatatcggcc gacctggtcc ttctactcta cctttttctt
    17161 caatcagttt atgggcagct agacgctgta ccgctcctga aacctgaact cctcgaatct
    17221 gctcgatttc agctcttgtg attggctgtt tataagcgat gattgctaag gtttcgacgg
    17281 cggcttgaga taatgtgttt gatgtccctt gcgcatatcg cttaagtaag ggagccagct
    17341 cttttttagt cgttaataca taatggcttt ccgtttcaaa aatatgcaaa gctgagtgcg
    17401 agttttgagt gtaagattct tttaattctt tcactaaact tgtgacttct gcttcgctga
    17461 gatttaacag tccgcttaat tcttcattac tgatcccttc ctcgccaaca ataaaaagaa
    17521 gggcttcaag ttcacttaat ttcgtcatgt tcggtatctc ctactgctgg ataaagcata
    17581 attgattcat agttttcttt ttgttgcgca atgatctgcc cttttttcat caattctagc
    17641 aaagccataa aagtagtgac aacttcactt ttagaaggtg actcaaaaaa agaatcgaaa
    17701 gtacagccat gcgcatttct ttttatacgc tcttcgataa ataccattcg ttcttcgatc
    17761 gttgtgtcat cgggcgtgat cgttttttcc actttttgag aaaatttctt acgttctaag
    17821 attttctgca tggcacggat caaatcgatt tttttgactt gtcctcgctt caacggcttt
    17881 tcagcatccg ctaacccatc gatgttcata ggttcttttg tgtaataaag acttcgttcc
    17941 tctgcttttt ctgtcagtct ttcagctgca tatttatatt tacggtattc taaaagctga
    18001 gtgaccaatt cttctcgagg atcttcttcc cataattctt catcgtctgt gacgaattct
    18061 tggacaggaa gcaatgtctt gcttttgatt gccatcaatg tagcagccat cactaagtat
    18121 tctcctgcaa cagctagctc gagtgttttc attgtatgga tataattcat atattgctcc
    18181 gtgatcgtag cgatcggtat atcatatata tcgatttcca tttgctgaat cagatgaagc
    18241 agcagatcga gaggaccctc gaatacatct aatttaatat tgatctccgt caactcattc
    18301 actctttctt ctttttcttt gctagccatt ttccaatgta aggctctgtg atttcagttg
    18361 cacggatgga gacatccggg tacttttcct gtaattcatc taacatttga aagcccatat
    18421 tctcaccgcg ataagacgga ttcaaagaaa tgtcatggat gatcagctga tcgttcgttg
    18481 cccagtaaat accaataatc ccttgaatgt tggttgaacc ttctggcgta aagaaaaaaa
    18541 gttcataatc gtcttcagat tcgtacgtat caatctcctt caacaaagaa gttttacctg
    18601 tcagtttctt atggaaactc aatagtccca tagcaatttt acggttttct ttccggtaat
    18661 gtgttaacat cttctcacct tcctatgact aagcccttgg aaaatgctgc ttataaacat
    18721 ccgtcattct tttcttcgtg atatgtgtat aaatctgagt cgtagagata tccgcgtgac
    18781 ctaacaattc ctgtactgtc cgcaaatcag ctccattttc tagcagatgt gtggcaaagc
    18841 tatgccgcag cgtatgtggt gttacttctt tgtaaatccc agcctctcgt actaactgct
    18901 tcagattttt ccagattcct tgccgagaaa gacctttccc atgattattg acaaatacat
    18961 gcatttcaga tgcgtccttt acaagtaatg gacgtgcttc gtctaagtag cgttccagcc
    19021 attggatcgc ataatcacct aaaggaatga tccgctcttt atctcctttt ccaactgtct
    19081 gtaccagtcc aagagaaaga tgaagatctc ccaatttcaa tccaatcaat tcactgacgc
    19141 gcatcccagt agcatacatg acttccaaga ttgcacgatc tcttatccct aacgtttttg
    19201 tcgtatcagg tgcttcaatc agcttttcta cttctgtcag agtcaatgta cttggtaatt
    19261 tctgtgcttt cttcggcgta tcgatatgtt gcatcggatc atgatcagtg atacgctctt
    19321 gccgtaaaaa ctgatggaat cttctgagac ttgagatcat ccgagtaaca gttgctgtcg
    19381 cttttttttc ttcatgcaac ttctccagaa aacggatgac taaaaagcga tcgacatcct
    19441 gccatgaagc aattttctgc tcctgtagaa aatgcaagta ctgttccaaa tcacgttcat
    19501 agctttgtcg tgtattggcg gacaatcccc gttcaatatt caagtagtgg agataatcgt
    19561 tgatttgctc tttcataata atccccctca tgcctctcta tcatatcaga taccgcttca
    19621 ttctgatagt ctttttccat aatctgagca aagaaaaagc cgtctagaca ctcagacgga
    19681 ctggtttctt ttttcttttt catagcattc ctgacagatt ccatggaacg ttagccgatg
    19741 atcttttact aaaaaatgat aacgttcttc tactacttgc tccacttcaa gtaaaagatc
    19801 ctcttctact tcctcgatcg tgccgcagtt caagcatagt aaatgatgat ggaaatgttt
    19861 ggcgccttct tttctcaaat cataacgggc taatccatca ttaaaactta ctttatcgac
    19921 aattttcaat tctgtcaaga tttcaagggt tcgataaaca gtagcaagtc caatttccgg
    19981 actctttttt ttcactaaaa agaagatttc ttctgcagat aaatgctctt tctcattttc
    20041 caaaagcaca agcagagtag cttctctttg cggtgtcagc ttaaaccccg cttcatgtag
    20101 ctgctgtttt gtttttttca tcgccgaaat agcattcatg accatttact caaccccaac
    20161 aatttataat aattacaaat aaaaaaagat ataacactat gttaattaaa attattataa
    20221 gctagttaag aaaaacatgc aagggattct caattagatt ttttgactag ttttgtcaca
    20281 ccgttttctt gtgtaatcaa tccttgtttc aaaagattac ctaatgcgcg cttaaatgct
    20341 cctttgctga taccaaaagc tttcatgatt tcttctggat ccgatttatc tgtaaagttg
    20401 atttgctgat ctgcagaacg ttctaaaatg gttaaaatca tttgtgcatc atctgatata
    20461 gcttcatatg ctcttggctt caatgaaaga ttcagtacac cgtctggtcg gacaccaatc
    20521 actcgacctt ttatctgctc gcctagacga ggttcattat atcgttcaga aggatggata
    20581 aacccaagat agaaatcttc cgttaaaacg tacgtacctg ttaatttcaa gcggtatgct
    20641 gttcctatca catctttgtt tttcatttct tctgttccat atttgcttaa agatttgaat
    20701 attttttcat ctgctaaact gccccaaata cggtcttttg catcaactct aagggaaatc
    20761 atcaagcgat cccctttttt aggccatagc tctgtcattg tcggcaattc atcaagagat
    20821 acgacaaagt ctttatctgg aagaccgata tcgacaaacg cacctaaatc ttttcgtgta
    20881 gcagtaacga ttccaaaagc gtaatgaccg atacggcttt taggaatttg tgtagtgatc
    20941 cgattttcat gtttttgatt ttggtaaccg aatccttcaa ctgcttcacc gattttgtgt
    21001 tcaccttctg atttgcttaa gccaaaggtt tgtccgtttt tttggacaaa gtagtttttt
    21061 tcattttcat caataataat acctgtaaat atagttgcta ataaatcgtt catttttttc
    21121 tccctctata gtgaaaggtt ttcttaatac atttctttgc tatcataaca taatgttatc
    21181 tacttgaata gctgagcctt ggtttggaaa ggtgaaaaaa ggagtatgac aacagttgtg
    21241 tcatactccc cttt
//
LOCUS       DBBGSZ010000041        20834 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.042, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000041 DBBGSZ010000000
VERSION     DBBGSZ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20834
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.042"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..181)
                     /locus_tag="ACIZE5_002183"
     CDS             complement(<1..181)
                     /locus_tag="ACIZE5_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HGC6109299.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDA"
     gene            complement(318..1604)
                     /locus_tag="ACIZE5_002184"
     CDS             complement(318..1604)
                     /locus_tag="ACIZE5_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6109300.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            1877..2455
                     /locus_tag="ACIZE5_002185"
     CDS             1877..2455
                     /locus_tag="ACIZE5_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGC6109301.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            2455..3384
                     /locus_tag="ACIZE5_002186"
     CDS             2455..3384
                     /locus_tag="ACIZE5_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6109302.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            3381..5117
                     /locus_tag="ACIZE5_002187"
     CDS             3381..5117
                     /locus_tag="ACIZE5_002187"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGC6109303.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(5180..6016)
                     /gene="pheA"
                     /locus_tag="ACIZE5_002188"
     CDS             complement(5180..6016)
                     /gene="pheA"
                     /locus_tag="ACIZE5_002188"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGC6109304.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(6013..6522)
                     /locus_tag="ACIZE5_002189"
     CDS             complement(6013..6522)
                     /locus_tag="ACIZE5_002189"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HGC6109305.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(6515..7810)
                     /gene="aroA"
                     /locus_tag="ACIZE5_002190"
     CDS             complement(6515..7810)
                     /gene="aroA"
                     /locus_tag="ACIZE5_002190"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HGC6109306.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(7823..8914)
                     /locus_tag="ACIZE5_002191"
     CDS             complement(7823..8914)
                     /locus_tag="ACIZE5_002191"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HGC6109307.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(8931..10097)
                     /gene="aroC"
                     /locus_tag="ACIZE5_002192"
     CDS             complement(8931..10097)
                     /gene="aroC"
                     /locus_tag="ACIZE5_002192"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HGC6109308.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(10099..11163)
                     /gene="aroB"
                     /locus_tag="ACIZE5_002193"
     CDS             complement(10099..11163)
                     /gene="aroB"
                     /locus_tag="ACIZE5_002193"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HGC6109309.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(11196..12218)
                     /gene="aroF"
                     /locus_tag="ACIZE5_002194"
     CDS             complement(11196..12218)
                     /gene="aroF"
                     /locus_tag="ACIZE5_002194"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGC6109310.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(12877..13851)
                     /locus_tag="ACIZE5_002195"
     CDS             complement(12877..13851)
                     /locus_tag="ACIZE5_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HGC6109311.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(13832..15715)
                     /locus_tag="ACIZE5_002196"
     CDS             complement(13832..15715)
                     /locus_tag="ACIZE5_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HGC6109312.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(15733..17958)
                     /locus_tag="ACIZE5_002197"
     CDS             complement(15733..17958)
                     /locus_tag="ACIZE5_002197"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGC6109313.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            18073..19107
                     /locus_tag="ACIZE5_002198"
     CDS             18073..19107
                     /locus_tag="ACIZE5_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6109314.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(19174..20187)
                     /locus_tag="ACIZE5_002199"
     CDS             complement(19174..20187)
                     /locus_tag="ACIZE5_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC6109315.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(20265..20453)
                     /locus_tag="ACIZE5_002200"
     CDS             complement(20265..20453)
                     /locus_tag="ACIZE5_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HGC6109316.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         5831 a         4525 c         3774 g         6704 t
ORIGIN      
        1 ttgcatctgt caacatccgc tgataattac ctaacccgtt aaatgtcata ttgacagggg
       61 gaccactttg aaaagacgtg atcaaagcca aaaccatcgg aataaaaacc atgattgata
      121 tcaaaatgac tggcaagatt aaaaaagcat gcccgttttt gaataaatct ttctgcttca
      181 ttcttttccc tccaattcta tcattgatta tctacatgaa aagacaagaa agacaatatc
      241 tgtaaggcag acgtgatctt ttttgtcttt tcgtttgtct gatgaaaaag cgaagaaatt
      301 cactttttta ccaccgatca attagccaat tgtgcttcta cttgtttttg tgtatctgct
      361 agtaccttgt ctgtctcttc tccattgatg attcgatgaa gagcttcagc tacgactgct
      421 tcaattgcat aggtctcatg tccgtaattc acttctggta tttcagatgt ccatgttgaa
      481 aaatcgtcaa agatcttttg accactgtaa aattcagaag cttcttgata agcttcttgt
      541 tcattcgcgc taagcatcgt agatactagt ccgatttctt tcgcaagagt gcccatcagt
      601 tcttcattcg aagcaaacgt tgcttctagg aaatctttcg ctgaatcttc tccagctact
      661 cctttgatca cataccagcc agcgccgcca aggttagaag cttgcgcttt ttgcagattt
      721 tctggaagtg caggtattgg tgcaatcttc cattttccag attggttttc tgctccttgg
      781 atcgttgaag aataccaagc gccagttggg ctagaagcta ctgctcctga ttgtatcgca
      841 gttactccag cattccagtc agaggtttgt tcgactagat cttctttcaa aagagtggca
      901 aacaattcaa gaccatactt taaagatgca ttgtcttgga tcgtgactgt ctccccatct
      961 tcagatgtat accattctcc tgcctgttgc ataatcatcc ttactcgacc aaggtcagaa
     1021 ggattgactt cagcgatttt ctttcccgtc ttttctttga catctcgcgc tacttgaata
     1081 tactcgtccc acttcagatt ctccatatcc tcttctgtat aacctgcttc tgccatcaga
     1141 tccgtacgat agaagtttgc tgttacgccc gaatcgaaag gaacaccgta tattttatct
     1201 cctactttgt ttaccgcaaa tttatacggt gcaaaatgat cttcctttac aatagcagac
     1261 aaattagcga atgcatctgg ataagaagtc aaatagcctt gtatcctata atcttcaatc
     1321 aagacgatat tgggcaatcc ttctgtattc ccgctcgcta aagcggtgtt cagtttctga
     1381 acgatatcat cctgagacat cgtaacaact tctatctctg tttcttcgtt ctcataaact
     1441 ttttttgctt cattcactgc tttgatattg aatgtctcat cccacgccca gacagtgact
     1501 ttttcttctt tgtctgctgt actactagca cttccgcatc ctgttaagaa acctgatgct
     1561 gccgctaaac aaacgactcc agcaattaac tttctgatgt tcatttttat ccgctccttt
     1621 tccatccatt agttgtttac gtttgctaca ttcatcatac caaaatttga aaacggtttc
     1681 tttattattc agatacttca aaaatttctc ctaaaataat aaaaaaatac aaatcaacta
     1741 tgacaaaagg aataatctta gcatctagac caaagatcga aatggtgagg tttctttaaa
     1801 ataaaaatat ccttgcattt tctcctagaa ataagtattt ttaaattaca agactattct
     1861 taaggcgggt aaaaaaatgc caatacgcgt aattcttatc gatgatgaac agacgatttt
     1921 agatggaatg aaacagttga tcaattggtc tgagcacggg tttcaattaa tagggacttt
     1981 ttccagtccg ctgaaagcgc ttgatttttc tttggtacat gcaatcgata tcgtggtcac
     2041 agatgtaatg atgcctgaat taaatggaat cgaattatcg cggctattaa aacagcaaca
     2101 acctgaaaca cagatcctta tcctctctag ctatgatgaa tttgatatgg ttaaagattc
     2161 ttttaaagaa ggcgtcgctg attatctttt aaagcctcga ttgagtcctg atttttttct
     2221 aaattcctta actgccgttt cacaaaaaat caaaaaaaag cccaacaaaa gcccaatcac
     2281 caatcgttat gagcagatct gcgagaatct ttcacagcag attgctggac aaactcgtcc
     2341 attgcttgac cctcttcttt ttgaacacac cttgtttttc tgttatatac cgaaaaacgg
     2401 ccattcagtt caaaacaagg ctctaaacaa aaacagtcga tcacccattc attgatggat
     2461 agcgacgatt cgtttactat ttatcctgtt tctacctttt cggaagaatc cggctatgta
     2521 atcaatactg attccaaaga tacacttagg aagtttgttc aaaagtttcg tcaagaagtt
     2581 tttccaggtg atttttttgt tgtttctgat tcttttgcaa tccaagatat caatgaaata
     2641 ttccaagaga tcagaaattg caccaaagga caacgtttct atcataaggg aaagaacctt
     2701 gcttatcagc atgaacttct tccgttatta accaaccacg agcagcaagc aagtagttat
     2761 ttaacaaaaa tcgttcataa agactacgct ttagctgtca aagaacttga gaatttcttc
     2821 acgacgatat tggaacagcc tattgatcca gcttatttga aacatgaggc aatcaatcgt
     2881 ttctatgcat tactcaacgc tttggctgac gagcatgttg ggaatgaaga actttctttg
     2941 ctcaagatcg cccttccttc tttattagcc gatgctgagt atttcgaaga tttttctatt
     3001 cttgtcaaag aaacacttga gaaactcacc cacttttctg caaatgcaaa aaaagacaat
     3061 ttcgatatct tgactttgat ctacgagttc gtccaggaaa attatgagaa agaaatcaat
     3121 ttacaacttt tatccgaaaa atatcatttt tcatatagct atctctcagc catctttact
     3181 gaaaaatttg gtatcaactt ttcaaaatat ctaaaaaaag tccgtatcag taaagccaag
     3241 ctctttttga cggaaacacg gcttactttg acggaaatct gtgagaaagt cggctatacc
     3301 gaactgggtt atttctccag agtttttaaa gaagagacag gaatgacacc ttctcaatac
     3361 cgtaaaggaa cttttgtaaa atgagaaaaa aaatcaaaga gcatgaactc tttgccaaac
     3421 ttctgttcat tttgttcatc ggtctttttc tgcaagccat cgtcatttct ttgtttattt
     3481 atcatcgatc aagggatgcc tatatccagc tgttcaatca atcgaatgat gtggtactaa
     3541 aaaagattca atctgaattt gaaagtttga atgatacaat cgagaataca ttagccgctt
     3601 ttgattctaa tccagctgtc aaaagctatt tttccaatga tccagcccaa catatggaac
     3661 agcttcagca actaagaaca atccaaaaaa tgaatgactc tctttcaaaa atccatccaa
     3721 tgatcgatta cgatgtattg atctttggag aaaatggaag aacttttgtc ggaaacgaca
     3781 tgctcactgc cgtatctgcc gattcttttt ttcaatctgc gattgctcag agagtgaatg
     3841 aacgtgctgc tgatacacaa atgctttttg cacaccacgg attgactctt cgcgataaga
     3901 aagcacccag cgtcttcttt gtcaaaaaac tgaaaaatac attgaatcac gtttacggat
     3961 atgctgtttt atcgatctca tccaagcaac tagcgaatct ttttcaatct gtagtaaatc
     4021 ctgagatatc gaagatctcc ttcatgaacg aagaacagac gatcatcgca tcaaatgaag
     4081 aaaatacaat tgggagccga tcaatgattt tcaaaaaact aacagtaggt gaaacaacga
     4141 tttcaaatgg acagcagttg acccgtcttc ctctgtaccg ccaggattgt acattactca
     4201 gtcaagtcga tcttcattct ttatctaacc aaatgggcgt gatttttccg attattttgt
     4261 ataatatcgt gacacttgct tttgctggct cattggtatt tatgtatttg gatcgacaca
     4321 caaaatcgat ctaccgcttg attgattcgc taaaacggct agaggaagat ggcttaaaag
     4381 ctactgttcc tgtacaagga agccatgaag tccaattgct agggaatacg atcaatcaat
     4441 tgctaagtaa tgctcagcat cattatgaac agacgatcca agacgaaaag aagaaacgtt
     4501 cgcttgaaat ccaaactatg caagcacaga tacagcccca ttttatttat aatacgctga
     4561 ctagcttgaa atttttgatt tggcagaaaa aaacagatga agcagttcaa ggaatcgaca
     4621 gtttcattac tttactaaga agtacgattg ggaaaaaaga agaagtgatt ccagtcaagg
     4681 aagaaatcaa aagcgtacaa agttacatcg atcttttgag tatgcgatat ggcgaaagaa
     4741 tctcggctaa aataatgatt cctgatgaac tgcagtcatt atctatgccg aatatgatcc
     4801 ttcaaccaat tatcgaaaac gcctatcttc atgcttttca caataaaacg caaggattca
     4861 tcacggtgta cggcaaaaca aaaaatcagc ttcttttatt cgaagtgatt gataacggcg
     4921 atggcttcga tactgaaaat accaaacaaa aaaatgatca tttttcagga atcggcatca
     4981 gccatgtaga tgagcggata cgcctaatgt atggcgatgc atatggctta acgatccaat
     5041 cagtgattgg gacaggaacg actgtaacga tttgtctacc gcttcttcct aaaaatcaat
     5101 cagaatatca aaaataaaga atagccaagc gctgattttt ttattttaag ttaaataaat
     5161 caatcagtat tcttgacttt catctacgcg tctcttctac tgtcagcact ggataacagc
     5221 ccaatatttg actttctcct ccgagcatct tgatttcttg gagcgcattc tctactaatg
     5281 tcattggacg gtccaacaac aaatcgatca cgaaaaaata ttctcccaag ctagttttca
     5341 atggtcggga ttcaatctta cttaagttga tttcccgcca gccaaaagct gccagcattt
     5401 tatgaagcat ccctggccga ttagcaggta gtgtcaagat gacactcatt tttactggag
     5461 ctgactgctg gctggtcatc tttcggtcac cgacgatcca aaaacgtgtc tggttcaact
     5521 cattatcttg gatattctca gctaagatct ccaatccaac atgctgtgct gtttctaatg
     5581 aagcaatcgc tgctgcgtct tctttcggat gttctgctac atacattgct gcagcagttg
     5641 ttgattctgt tgctactaaa ggaacattag gataatgcgt ttctaaaaac tgttgtgatt
     5701 gtgctagtgc ttgtggatgt gaaaggattt ttgtaatctt tgttgctgga ttgcctaaaa
     5761 gctgctgctt gataggaaga acgatttcac ttttaacttc gacttctgga tgtttggaaa
     5821 gaagatcgat tgtgtgatga acagctcctt ccaatgaatt ctctacagga acgacagcca
     5881 gatcgacttg tttgcgaaac aaagcgcgca aacaaacagg gatggaagca tacgcagtca
     5941 attgttctgt aggaaatagc tgacaagccg cctgataagt gaatgaactt tctggcccta
     6001 gatagctgac gttcatatgc ttttgatcct ttctataatg gtatcgatga tcttttctgg
     6061 tgtttgattg gtcgtgttga ttcgatgtgt cgcactttct tcataccaag aaagtcgttg
     6121 tgccaataat gcttttattt cttctcttgt ttttccaaga gctaaaggtc gaatagacgt
     6181 ttcatcttgt tggatacgat caactagaca gtccgcttct gcctctaagt aaagaacaat
     6241 cggctgtgtt tttaaaaaac gccgattttc tgcactttgg acaatccctc caccagtcgc
     6301 gataattttg tcttcatttg acagctttct taaaatatct gactccactt ttcgaaagct
     6361 tttttcaccg taatagtgaa aatattcggc aatcgacaat tggatatgtt cctcaatctt
     6421 tgtatctaaa tctacatact ctttttgtaa acattgagct aaccctttac cgattgttgt
     6481 ttttccagcg cccatgaaac caatcagcaa aatgctagcc atgagcttct cctcctgaca
     6541 caagttctgc taaatcgtca aaaaatgccg gataagagat tgaaacagct tcagctcctt
     6601 ctagttcgca aggtccatca gctatcaaag cagctacttg cagcatcata ccgattcgat
     6661 gatcgcctct gctggacact tttgcgccat gcagaggtgt cggcccatgg atgatcagac
     6721 cgtctgctgt cgcttttatc tttgctccca ttttctgtaa ttcttctgcc accgcatcaa
     6781 ttctgttggt ttcttttact tttaattctt ctgcgtcttt gatgatcgtg attccttctg
     6841 cttgagtagc cactaaagct agaatgggca attcatcaat cagacgcgga atgatttctc
     6901 caccaatcgt tgctttcttc aaatgactcg tcttgacact taaatcagcc gattggttct
     6961 gttcattgtg attcgtctgg gtaatcgctg cgcccatctc ctccaacaca tctaagatac
     7021 cagttcttgt tggattgacc ccgacatttt ttaacaacag ttggctttcc ggaacaagaa
     7081 gtcctgctgc tagaaagaaa gcagctgatg aaatatcacc tggaacagtt atctgttgac
     7141 cagttaattt ttgcggtccg gtcactatga tcgttttatc ttccactgtg atccttccgc
     7201 caaattgacg aatcatttct tccgtatggt tacgggaacg ttctttttca acgattacgg
     7261 atgtgccttc tgcttgtaat gccgcaaaca gcaaagcaga tttgacttgc gcactggcta
     7321 caggcatatt gtatcggata ggtgataaag agcgggttcc tgtcacagtg attggtagat
     7381 actggtcatt ttcttctcct tgcaagtcag cgcccatctc gcgtaaaggt tccatcactc
     7441 gccccattgg acgtttagac aacgaagcat ccccgaacag agtagtcgta aaaggctgtc
     7501 cagccaaaat acccatcaat aaacgtatgg tcgtaccgga gtttcccatg tcaattgatt
     7561 cggttggttg gacaaatgag tggctaccgc gaccatgaat cttgatcacc tcttcctctt
     7621 cttcgatctc gacacctaat tgttggaagg catgtaaagt actcagacaa tcttctgcgc
     7681 gcaaaaaatt ttgtatagtc gtcgttcctt cagcaattgc tccaaacatg atgctgcgat
     7741 gggaaattga tttatctgct ggtatcctaa cagtccctct taatccatgt atttgttgta
     7801 ataattgcat ttatccagcc tcctatttga tccagcaatg ataactggta ttagacataa
     7861 tgattctttt tgcttgtaac aaatcctgtt ggtttttaaa actgatttgc agtattccta
     7921 aaatatcttc cctggtctct tggatcttca aattaatcaa agaaactccc gcttttccga
     7981 tcagtccagt tacttctgca ataacgccag gttcatctgg cacatcgata aataaatcaa
     8041 aaaaggcagg aatcgcgcct tgcttatgga caggcaactg gtctcgactt tcttttgccc
     8101 gattgaaaaa agaaaagatt tccgattggt tctcagtcat gatccattct gctatttgtg
     8161 tcatttcttg ttgccaatct gccaatcgtt ccaataatat ctgcttattg ctcaacaaaa
     8221 tatctgtcca catgacagga tctgaggaag cgatcctagt gatatctcga aagcctcctg
     8281 ctgccagttg tttggctcgc ggatactctt gattgaattg ttctgcctga ttgactaagc
     8341 cagctgccag aatatgtgga aaatgactta gcattcctgt tatacggtca tgttctcttg
     8401 ctgtaagagt tacatatttt gctttggttc cgcaaaatag ttcttgcagt ttttcaacat
     8461 cttttttcgt cttttccaaa ggtgtaaaga tgtaataggc attttcaaat agtttagcat
     8521 ctgctgcctg tatacctgat ttatgagaac cagccattgg atgtccaccg acaaaccgaa
     8581 gatttttctg ctcagcggat gtcacgactt gctgcttcgt actgctgaca tccgtaatga
     8641 tgacgtgatc agacaagttg attctttcaa ggacatcaag ataagctaag gttgtacgga
     8701 cgggaacggc taataagata acgtctgctt gttctgcacc tgtttcaaaa tcacttgcaa
     8761 cgtaatcaac gatctgctgt tctactgctt gctcacgggt ttttgactga ctatcccaac
     8821 caactactat cagttctgga ttggtctgac gaatacaaag tgccatagaa gcaccaatca
     8881 gtccaagccc cacgataaaa acatgttgtg ccatcttatt tgcccccttt ttagtaatgt
     8941 ttcaagtagt cacggtactc cttcactgca gctttcaact caacaagcga atcacttggg
     9001 aattttgaca atagctctgt cgctaccaca gtggctacaa cattttccgc aacgacgcta
     9061 gctgcaggaa ctgctgtact atccgaacgt tctacacttg ctttgtaagg ttcttttgta
     9121 tcgatatcaa cactttgaag tggcttgtac aatgtaggaa tgggtttcat gaccccgcga
     9181 atgacaagtg gttcgccatt ggtcattccg ccttcgaagc cgcctagatt attggtacgt
     9241 cggaaatagc ctctttcttc ttcccatagg atctcatcca tcacttctga gcctggtaat
     9301 gaaccagaag tgaatccgac cccaaattct acgcctttaa aggcattgat actaaccaca
     9361 gcttgtgcga ttttggcatc tagcttcgtg tcccattgta cgtagcttcc taatccagct
     9421 ggaacgcctc caacgagcac ttctacaatt cctccgatcg tatctccatt tttctttgtc
     9481 tgatcgatca aatcttttat tctttgctca actgctggat caacaactcg tacttctgac
     9541 gcttcagaaa tttctttgat ttcttgaatc gagatatttc caggtatttc tgcttggatt
     9601 ccaccaagac aaatcacgtg tcctgctacg atgatgtcaa gttcttccag aattttcttg
     9661 gcaattgcgc cgattgctac acgcatggtc gtctctcttg cagaggaccg ttcaagcaca
     9721 ttccgaagat ctcgatgatg gtatttcata ccgcctacca aatccgcgtg tcctggacgc
     9781 ggacgtgcaa ctcgccgcag tgattggtct ttttcaggca cttctgctac agacatgaca
     9841 gttgtccaat ttttccaatc tttattttct accactaaag tgacaggtga accaattgtt
     9901 ttgccgtgac ggatgccaga cgtgatccga acacgatctt tttcgatctt catccttcct
     9961 cctctgccgt aaccagcttg tctgcgagcg agttcgtgat tgatttcttc ttctgacaga
    10021 ggtaatcctg ctggtagtcc ttcaataatg gctgttaatt ctggtccatg ggattctccc
    10081 gcagtcatat aacgcatctt acagtcctcc taagtaatct ttgaatgtct ctgtgggaac
    10141 aggaacgatt tttgcttgcc caatcttttc tagcaagatg atattcaatt ggcttcctct
    10201 tgctttctta tcatgggtta tcgcgtggaa taattcatct ggatgactta gatcgtacgt
    10261 aatcggcaga tggaattttt gaagtatcct ttctaaagca gctgtcgatc cagttggaga
    10321 caagccgatt ttttctgcat gagaagtgat ggctaccatt ccaatagcta ctccttctcc
    10381 atgactgact accccatatc ctgctgtatt ttcaattgca tggccaattg tatgaccaaa
    10441 atttaaaata agtcgatttc cttggtcaaa gacatcttct tccactactt ttcgtttgat
    10501 ttccaacgta gcagtaatga ttggaacagc atgttccaga agatcttttt cgtctttcag
    10561 ctcgttcagc tgtttccaaa gcgttgcatc tgctatagct gctgatttga tgatttcagc
    10621 gattccttct cgtaaacgac gtaccggcaa agtttttaga acctcaggat caatcaatac
    10681 accagctggc tggctaaatg ttccgacaag gtttttcgct ttgtttgtat tgactgctgt
    10741 cttcccgcca atactagaat ctacttgtgc aagtagcgta gtcggaattt gaacgaaatg
    10801 gatcccacgc atgaacgtcg aggccacgaa tgctgctaga tcacccacca ttcctccacc
    10861 aagtgcaagt atcccatcgc tgcgggtaaa atcattatct gctaaaaaat cgtataactc
    10921 agctgcttgt tctaaagatt tactggtctc acccgccggt acgattgaaa ggactggttc
    10981 aaaattagct tgtctcaatt ggaacatgat tttttctgca tatagtggag caacgtttgt
    11041 atcagtgatc acagctactt tttgaggtct ccaaatcgtt tgaagccatg atccagcctg
    11101 ttctagtgcg cctttttcaa tatgaatatc gtatttttgg ttatcaacat gtacagtaag
    11161 cattcgtttc acttctttct tttaaaaagc tggaattaat cgagtgtctg aatcttttcc
    11221 attgcttctt tcatgatcgc aacttctttc atcatgcgtg agtaagtctt ttcattcaac
    11281 gattggggac cgtctgacca agcatttgca ggatcaggat ggatctctac gatcatgcca
    11341 tctgctccgc ttgccacacc cgcacgagcc attggtggta caagttccca aattcctgta
    11401 ccatgacttg gatcaacaat cacagggaaa tgagttaatt ttttcatcaa tgggacagca
    11461 cttaaatcaa acgtattacg tgtcgctgtt tcgtaagtcc gaatcccacg ttcgataaaa
    11521 atgacaggag atttgtcttc gactgcaatg tattctgcag cattaagcca ttcattgatc
    11581 gtaccggaaa ttccacgttt caatccaaca ggtttacctg ttttaccgac agcagatagc
    11641 agtttaaaat tttgcatatt acgtgcgcca atctgtagga tatcgctgta ctcagccacc
    11701 atatcgatat gcccttcatc catcacttca gtaatcactt tcattccaaa ttcatcagcc
    11761 gcttgacgga tgtatttcaa tccttcttct tctaaacctt ggaaagcata tggagaagta
    11821 cgtggtttga aggcaccacc tcgcagaatt tttgcgcccc cggctttggc cattcgcgca
    11881 cattctctga tttggtctaa tccttcgata gaacaaggac cagccatcgt cacgaaactg
    11941 ccgtcaccaa tttttactcc gtctacatcc acgactgtat tgccaggatg gaattctcga
    12001 gaagtcaatt tgtatgtgtt taaaatacgc acagcatttt ctactccttc atagcgtgta
    12061 aatgctcctt cttgtaaact tcgcgtatca ccttttagtc caatcactac tcgttctgtt
    12121 ccttgatcga ttgagacttt gaatccttct ttttcgatat gatcgacgac tttttttatt
    12181 tgttcttccg ttgcttcttt tttcataatt actatcattg tttttcccgc tttcttttgt
    12241 ttacttatct atcttggctg attttctcta ctttttcaag gtggttttac attaattcct
    12301 actaaatgac cgtgtcctgt tgttctcatt ttcgctcctt ctttcctact tatgacccag
    12361 ataatcaaca aaaaaagatg tccctgtagg aaattgcctc tacagtgaac atcttcaacg
    12421 agccttaaaa agcgctgcaa aaatataaaa tagccactat agatgaattt ctctacgtgg
    12481 ctgtaagtcg tgtttaaaaa tctttagcca tcatagatac aaacctggtt tgtttgtacc
    12541 cacgaagtca tgaatacaaa cctatctaaa atagctaaag taatacgtat tcagttttgt
    12601 aagttttcta gatttcataa aaaatcgctc caaactgatg taagaattgt acctagtata
    12661 gacataaaaa aatcgactgt caatcatttt tatgaaactt tttttaattt tctgatagtt
    12721 aactttgttt ttcagaaaaa taacaattgg ttttattgaa gaaaatagtc atgaacaaaa
    12781 gtatctgaga acttttttac tctcttgttc atgacatata gaataaagca gctttgtctt
    12841 gtaaactccg tttttcaaat aataatctaa agattgctac tgaataataa agccgatttc
    12901 atggtcctct tcgctgctga ttcggtaagg tgactcaaca tccgctcccc agctattgat
    12961 acccccgact cctcttactt ttgcaaaaat cgtaagaacc gttcgtcttt ctggcggtag
    13021 ttcttctata tgtgttgcct gttccagttc ttctgctttg aatggtaaag cggaaaaagc
    13081 aaatggcgta tcctgctgtt caaatcgcaa cgaaaaatct tcttgatctt tatccgtatt
    13141 atccaacgtt tgatttcttg ttagttctac ccatttcgtt tccatatgca tgccgcattc
    13201 ttggggaaca aggtatgggg aaacggggag tcctgccact ttataaatac cttcgacacc
    13261 accagccatc cgatccggat atgtttcccc tgataggcct tcatactcaa aaaattttgc
    13321 tttcgttggc ataatgaacc ttaaacccaa tgcgggtaat tccggtaatc ctttttgtcc
    13381 ataataatgc atattgacaa gcattttacc ctctccagcg atttggtagg aaattgtcac
    13441 ttgggttttt ggtactgtgt tgatttccag tgtaaaaatg atttcaaccg tttcagcgta
    13501 ttcattactt gaatattgat tatttactgg agcaatcggc aaatcgatct ttttattgtc
    13561 caccagtact tctatttctt tgacttttgg atacaatccg gctcctaacc acataccgga
    13621 tttaaatcca aatccgctac ctctgtcatt atcggtcgtt gctcgccaaa aaactggaag
    13681 tgtttcccgg tatagccatt cttttccgtt tttattgagc gattccagtc cgcctcttgt
    13741 ataagaaaaa atataatgcg tattccccga tttgacacct aatgtacagt cgccgaagac
    13801 gattgcaact ttttccgtat ccatatgact tttatttact gtatttttca taataatatc
    13861 ttacctcctg catggcgggt ttttcttgtc catctgcaaa aacgatccca ttccctgaga
    13921 attcatagtc acttggttta tcgtcaaagt caccgccata gcgcatcact tctctgcctg
    13981 tgattggatc agtcacttgg atcgcctgat ctttaaaatc ccatatatag cctccttggt
    14041 acatttcata acgatcaagc aacgtcatgt aagaatccat tccacctaac gaattcccca
    14101 tgtcatgcat atattcacat aagatgaacg gtttttccgc tttattttca aggtagtcaa
    14161 tgatctcttc tggtggcgca tacatgcagc tttttacatc tgaaatcgaa tcttcgaatg
    14221 ctggatttgg aaaattccct tcataatgga caagtcgatc ggggtctact tttttgaagt
    14281 aatcgttcat ttgtcgaatg ttttcttccg cataagattc atttccaaga gaccaaaaaa
    14341 gaatacttgg atggtttttt aatgtttcga aattcgtttt tgctcgatca agaacagccg
    14401 cctgccactg aggtactgca cctggtacgt tgtaagaagg ctcaaatgcg cccatttttt
    14461 gccatgagcc atgggattcg aggttcgttt ccgccatcac atggattcct gcttggtcgc
    14521 ataaataata ccaagtgatc tggttggggt aatgagatgt ccgtacgccg ttgatctttg
    14581 cattttttat gatagccaaa tctttttcca tatcttctat agtgatggcg cgtccttttt
    14641 tcggatgcca ctcatgtcga tttaccccgt tgataatcat ccgttttcca ttgaagtaga
    14701 tgattttatc tttgatttcg attttacgaa aaccgaagga atagtcaata tactccgtta
    14761 ctcttttttc ttcgtctatc gtctccaatt caagcttata taaattgggc tgaaaatgcc
    14821 cccacagtgc cacattttca aatccatcga tgcgaatcgt catttgctct tttaacggat
    14881 attgctgttg atagatttcc ttcccatcag gatctagtat cgctacattc agctgactgt
    14941 ttttggctac ttgctcaaaa gacaaatcta cttcaagttt gccattttga catttgtcat
    15001 ctaagcgagg tttgatccaa agatcttcta aatggttttg tcctcgagca actaagaaga
    15061 catctctgaa gatcccaaaa aatcggaaaa agtcctgatc ttccaagaat gcagctgtac
    15121 ttcttttgta aacctccaca gctagaatat tttcttcttc caaataaggt gttaaatcaa
    15181 attcagacgg agtgaacgaa tcttcggcat acccgataaa atgaccattc aaccaaataa
    15241 acattgcttg ttctacacca gcaaaatgaa tcgagatttg ttttcccttt agaccttctt
    15301 ctaatcgaaa agtcgtcaaa tacgaaccaa ccggattgtc tttagcagct gaaaagatcc
    15361 cttccgcctc tttctcaggg cttgtcgtga aagggggacg gcgaaataca tgtccctccc
    15421 acggatacat cgtattgatg taatggatct tgtcataatt tgctaattca atatgactag
    15481 gaacagtgat ttcatcaaaa gaacaggcat caaaatcttt tttataaaat gtttttggtc
    15541 gtaccgaagg atttggcgaa taacaaaaac gccatgatcc atttaaagac tgtttaaggg
    15601 aggatgtggt ttctacttct tcccttgttg cataacaaac atgatcgcta tgtgcatttg
    15661 attggttcac tctaaaaact tgtggatcat ctaaccattt tatatttgct ttcatacttt
    15721 tttccttctc tctcataact ttttgaaatg aagcagttct gtttggaaat caccttgaaa
    15781 atcggggaag taaagtccaa ctgtcatcaa ttcggccccc gaaaatatcc gcttcgaggt
    15841 ctgttcctga taaagtgcct catcatctaa ccccatcaga tatacttcat ggaacgctgg
    15901 ttgagctgaa gctagtatcc tccctaaaaa cacaatagct tcatcttgtt taggagacac
    15961 aaacatccat gcggcaatat tttcttcaaa aggactcgcc aaacgataat aatggccata
    16021 ctggatcacc ggacgaatcg tttgatagga tataatttgg tcttttactt gctttttttc
    16081 ttcaggagac agctttgtca aatccagttc ataaccaaaa acagcgctca tagctgtttc
    16141 tcctcttgtt ttcaacgaag tagatctgtc ggtctgatga tttggtacag ctgatacatg
    16201 agctgtgatg gacgaaatcg gataagcaag gcttgttcca tattggattt tcatacgctc
    16261 cactgcatcc gtgttatcac ttgtccatga ctgcggcata taataaataa acccggcatc
    16321 aaaccgtcca cctccaccag aacagccttc ccataagatt tccggataat cagttgtcaa
    16381 atgttcaagt agttcataaa gcccgagcat ataacgatgc gctacttctc cttgtctctg
    16441 tgggtcaagg gtaatcgaat agacatctga aagcgaacgg ttcatatccc atttgatgta
    16501 gtcaagagga atcgtatcta aaatctttct catttgtttc tcaatcgtct gccgaacatc
    16561 taaccttgta aaatccagta catgttgtga tctggaagca gaaggcattc tacctggctc
    16621 ctgcataaga aaatcaggat gtgttcgata cagttcagaa tcaaccgaga tcatttcagg
    16681 ttcaaaccat aaaccaaatt tcaatccttt gctatgagca taatctgcta tttcacgtaa
    16741 tccatttgtc aacttgcctt catactcgaa ccagtctcct aatgaagaat tgtccgcatc
    16801 tctttttcca aaccagccat catctaatac gaacatttcg atgcctagct cctttgcttc
    16861 atcaatgatc gccttgattt tttcactatt gaagtcaaag taagtggctt cccagttatt
    16921 gaccagaatc ggccgttcag caaattgatg acgacctctt gcgattcttt cacgtagcaa
    16981 ctcatggtgg atctgactca ttttgttcaa tccctgactt gagtaagaaa ggatcatttc
    17041 aggtgtttga aaagactggc ctgcattcaa ttcccacgaa aaacgatggc tgttgatccc
    17101 accgacgact ctcaattgat tgatctgatc tttttcaagt tcgaaagaat ggttgccgga
    17161 ataaacaaat tgaagtccga tcgcttctcc agtattttct gtcgtatgat gatgaactaa
    17221 agcaataaag ttattcatat ggtgactgct cgttcctcga cggctttcaa atacttttgt
    17281 tccagataaa acagattgcc gtgaaatctg tctttcattg acatgtgctc ctggcaaagc
    17341 aatgacttca tcaaatcgcc tagtatgggc aaagtctagc tggaaactag ccgctttttc
    17401 tagtttgatt gtttctccgg tttcatttct tatctttaca gatcgtgtga tcactgctct
    17461 atcagtaaat atggtataga acaaatcgaa ataaatcgct gtttctctat ccttaagtga
    17521 aatcaccaac gtttgtgcct ctgacttgtc catcacataa gtttgaggca agccttcgat
    17581 ctctggcttc ccatctgtaa tataatggct gtcatatctc agatccagta agtctgatcc
    17641 attcttgcgc tgaatgatcg atgcgggcgt tcgaaagtcc atgctgccat gagaagagta
    17701 ttcttgcggt agtgtatctt tcgacagaga ccggtcagga tttaagggaa catttcctga
    17761 aaatccacga tctcttcggg gataattttt attgtctttg tactgcttga ctggtttgcc
    17821 aaaataaata tgcgccaata cattgctttc ttctatcttt atcagataag aaagaaatgt
    17881 atttcgtaaa tggaagactc ggctcttttc atcaaataag atgaaatttt tatctgtttt
    17941 tctatgcgta atatccatca tttcactccc aacaaaacgg aaaccgttta ctttttttta
    18001 taattcctgt atactgttta ctaaacaatt ttgtcaataa aaatttttta tttttttgag
    18061 gagtgtgtaa aaatggttgg aattagagat gtcgcacgaa aggcaaatgt ctctcctgct
    18121 acagtttccc gtgtgttgaa taacgatcag acgatccatg tggctcagac tactcggcaa
    18181 cggatagtag aggcagctgc tgcgttggat tatgacatca gtactcgtaa atatatcaaa
    18241 aagagaatgc cttcgattgg tgtgatctct acgatcggca aagcgagcga agaacaggat
    18301 atctattaca aacatttgcg agtagggatg gaagaagaag ctcgacgtct gcatttaggg
    18361 atgaatcgaa tctataatct atctgataat cctaaacaat gggaagatct agatcagtta
    18421 ggtgcggtga tcgttgttgg gactgttacg aaagaatcga ttaccgcctt gttaaaacaa
    18481 aacatgcaaa tagtcgtcgt ggataaccct gacatccagc aagaggtcga tatggtgtat
    18541 gcagatcttg aacggatgac taaaaccgta ctggaattgt tcttagaaaa tggtcataaa
    18601 agaatagcct atatcggggg atataaagtc gatatggatg aattcggtgg gaagcagatt
    18661 tctataaatg aaaagaggat gcgtgcctat cagcatttta tgatcgatca tcacttagaa
    18721 aaatatatgt cttatcatct aggtggctgg acagaaaaac aaggtgaggt acttgcgact
    18781 aatctattag aaaatgaatc ccctcttcct actgccattc ttgtcgggag cgatccaatg
    18841 gcaattggtg tctatcgggc attgaaacaa aaaaatatcc aaattggaga agagattgtt
    18901 gtagcaagct ttgataatat cgagacaatc gcaaacctct cccctggctt gaccagtgtt
    18961 caaatcaatg cgaaatcaat tgggcaagca gctgttcgaa tggcattgga gcgaattgac
    19021 ggtatacggg acgaaccaat cattttgact tatcctgcac gattgattgt tagggaaagt
    19081 tttatcccaa gaacaaaaag gtattgaaag agaggttgtg aaaagccgct tcgtttcttc
    19141 atactcaaaa cgaaacggct ttttcacaac ctcttactta tacttattca caaaatccaa
    19201 tgtctgctgg taacaatttt gcgattcttt tagcgtgtaa tcaaattggt attcatgggt
    19261 aatctctttt tttgtatctg tataaaacaa ggattgcacg ggtaccttta attctgtcaa
    19321 ccgattttct aatgcttgac cttgctcctg gaatgagtat gcatttccgt cagttatata
    19381 cgttggcgga aattccttag aaacatggtc agccacacta gcttctttca attgctcact
    19441 cgttttccaa tcttttgttc caatcaacga ccacgcaacg gttttgacga aaaacttcat
    19501 aaatcgatca tccgaatgct gctgtgctgt tagcttcaaa tcaacaggtc cgcaataaga
    19561 aatggttcct ttcagactat cttttggaag tagctgtttg attttcattt gtttagcata
    19621 cgcatcattc gtttgtatag ctgcatattg caatgcgatt tgtgaacctg cactatctcc
    19681 accaaaaaat aattgttcca tgtctagcaa tttgtcgtct ttttcttcag ctaataaatc
    19741 tttgatcagt tcattcactt gaagaacttg attagggtat tctgaatcag gcgctaattc
    19801 ataattcatc gcaaccactg cgatgttggc gtctgaaact aattttgtcg caaattcttt
    19861 gacacccgat ttatctccgc cgacgaatcc tccaccatgt acccaaaata gaacaggaac
    19921 aggccccttg ctgttttttg gatagtagat gtcataagta ttctctttat acttggactc
    19981 atacgtcaaa tctgtttttt tcgccacgtt tttttctgct tgatcgaacg tttttttatc
    20041 agtgatttga acagtatttg aaaacatatg gttgatcaag aatgctccag gtctggggga
    20101 aagctggaag gcaagaaaga ttgcaaacgc gatcccaaga atgattccga agaaccatcc
    20161 gataaattta agaattttct ttttcataag gctccctcag tagttagtat taagcattct
    20221 gattatacca tagtgttatt tcctatcaag ctctcctaga tgatttaatg attttcccca
    20281 aacttcttct gcaatgcttt tgacaaaaga aattttttcc attgttcttc aaacaaaaca
    20341 ttttcttctt ctgttgaagc aaatccacat tgaggactta agcacaaacg atccaaaggc
    20401 agatatcgtg tcgcttcgta gatccggtca atcacttgct ggtgctcttc catttcgcca
    20461 tttttcgtta cagtcaaaat ctaagacaac taatttatct tcagagactt tctctaaaag
    20521 aacaaaactc ccagcacgtt cactatcgta ttctaaataa taggcacgga cattttcttg
    20581 agtaaaataa tgggtctgct acgtcgtcat cccccctgat gccgccaaaa tcgaataata
    20641 atttccgcgt caaacatgta tatttagtgt tgaatcattt gagaatatga aaataaaaat
    20701 ctttttgatc aatcagttaa tcaaattgaa ataacgaaaa atctgagaca gaatgacgtt
    20761 cattctgacc cagatttgat tttgcacaac tcaacagtcc ttattggcaa atcgccaaaa
    20821 taatgtagac taac
//
LOCUS       DBBGSZ010000042        19107 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.044, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000042 DBBGSZ010000000
VERSION     DBBGSZ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.044"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..1835)
                     /locus_tag="ACIZE5_002201"
     CDS             complement(<1..1835)
                     /locus_tag="ACIZE5_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HGC6109317.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWR"
     gene            complement(1832..2536)
                     /locus_tag="ACIZE5_002202"
     CDS             complement(1832..2536)
                     /locus_tag="ACIZE5_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HGC6109318.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            complement(2548..4857)
                     /locus_tag="ACIZE5_002203"
     CDS             complement(2548..4857)
                     /locus_tag="ACIZE5_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HGC6109319.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            complement(5052..5516)
                     /locus_tag="ACIZE5_002204"
     CDS             complement(5052..5516)
                     /locus_tag="ACIZE5_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109320.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            complement(5516..6142)
                     /locus_tag="ACIZE5_002205"
     CDS             complement(5516..6142)
                     /locus_tag="ACIZE5_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HGC6109321.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            complement(6149..6514)
                     /locus_tag="ACIZE5_002206"
     CDS             complement(6149..6514)
                     /locus_tag="ACIZE5_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HGC6109322.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            complement(6504..6842)
                     /locus_tag="ACIZE5_002207"
     CDS             complement(6504..6842)
                     /locus_tag="ACIZE5_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109323.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            complement(6832..7158)
                     /locus_tag="ACIZE5_002208"
     CDS             complement(6832..7158)
                     /locus_tag="ACIZE5_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HGC6109324.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            complement(7139..7417)
                     /locus_tag="ACIZE5_002209"
     CDS             complement(7139..7417)
                     /locus_tag="ACIZE5_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HGC6109325.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETD"
     gene            complement(7419..8783)
                     /locus_tag="ACIZE5_002210"
     CDS             complement(7419..8783)
                     /locus_tag="ACIZE5_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HGC6109326.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            complement(8796..9365)
                     /locus_tag="ACIZE5_002211"
     CDS             complement(8796..9365)
                     /locus_tag="ACIZE5_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA];
                     GO_process: GO:0019082 - viral protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HGC6109327.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            complement(9337..10524)
                     /locus_tag="ACIZE5_002212"
     CDS             complement(9337..10524)
                     /locus_tag="ACIZE5_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HGC6109328.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            complement(10588..12315)
                     /locus_tag="ACIZE5_002213"
     CDS             complement(10588..12315)
                     /locus_tag="ACIZE5_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HGC6109329.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            complement(12312..12764)
                     /locus_tag="ACIZE5_002214"
     CDS             complement(12312..12764)
                     /locus_tag="ACIZE5_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HGC6109330.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            complement(12876..13256)
                     /locus_tag="ACIZE5_002215"
     CDS             complement(12876..13256)
                     /locus_tag="ACIZE5_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HGC6109331.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            complement(13253..13639)
                     /locus_tag="ACIZE5_002216"
     CDS             complement(13253..13639)
                     /locus_tag="ACIZE5_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HGC6109332.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            complement(13641..13919)
                     /locus_tag="ACIZE5_002217"
     CDS             complement(13641..13919)
                     /locus_tag="ACIZE5_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109333.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            13967..14695
                     /locus_tag="ACIZE5_002218"
     CDS             13967..14695
                     /locus_tag="ACIZE5_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HGC6109334.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            complement(14841..15317)
                     /locus_tag="ACIZE5_002219"
     CDS             complement(14841..15317)
                     /locus_tag="ACIZE5_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="HGC6109335.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(15277..15633)
                     /locus_tag="ACIZE5_002220"
     CDS             complement(15277..15633)
                     /locus_tag="ACIZE5_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109336.1"
                     /translation="MKKVNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVL
                     KIEQNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIR
                     GGVCEISLVKRLPRTR"
     gene            complement(15611..15796)
                     /locus_tag="ACIZE5_002221"
     CDS             complement(15611..15796)
                     /locus_tag="ACIZE5_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109337.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            complement(15797..16069)
                     /locus_tag="ACIZE5_002222"
     CDS             complement(15797..16069)
                     /locus_tag="ACIZE5_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH/PUA domain-containing protein"
                     /protein_id="HGC6109338.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            complement(16066..16266)
                     /locus_tag="ACIZE5_002223"
     CDS             complement(16066..16266)
                     /locus_tag="ACIZE5_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109339.1"
                     /translation="MKVREQFKIVSDEGNVYKIKIVNINEYREADHKYLVDLYMNDKY
                     LGEGFCGDSLFDDERILKEETE"
     gene            16394..16606
                     /locus_tag="ACIZE5_002224"
     CDS             16394..16606
                     /locus_tag="ACIZE5_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109340.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            complement(16639..16833)
                     /locus_tag="ACIZE5_002225"
     CDS             complement(16639..16833)
                     /locus_tag="ACIZE5_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109341.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(16846..17028)
                     /locus_tag="ACIZE5_002226"
     CDS             complement(16846..17028)
                     /locus_tag="ACIZE5_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109342.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKI"
     gene            complement(17025..17165)
                     /locus_tag="ACIZE5_002227"
     CDS             complement(17025..17165)
                     /locus_tag="ACIZE5_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109343.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            complement(17655..18020)
                     /locus_tag="ACIZE5_002228"
     CDS             complement(17655..18020)
                     /locus_tag="ACIZE5_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109344.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            complement(18060..18362)
                     /locus_tag="ACIZE5_002229"
     CDS             complement(18060..18362)
                     /locus_tag="ACIZE5_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HGC6109345.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            complement(18362..18661)
                     /locus_tag="ACIZE5_002230"
     CDS             complement(18362..18661)
                     /locus_tag="ACIZE5_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109346.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            complement(18654..18818)
                     /locus_tag="ACIZE5_002231"
     CDS             complement(18654..18818)
                     /locus_tag="ACIZE5_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109347.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            complement(18824..19093)
                     /locus_tag="ACIZE5_002232"
     CDS             complement(18824..19093)
                     /locus_tag="ACIZE5_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109348.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
BASE COUNT         5345 a         4058 c         2953 g         6751 t
ORIGIN      
        1 attctccaag ctctcttttc tgcatctgtt tttaattcat caggataccc accaggtgtt
       61 tctcctccgc cagatggacc gccattttgt cctggtatca cttctttacc tctaacagta
      121 agttttccct gaatatctaa atcaccgaaa taatatgctt ttccgtttcc taataacaca
      181 aatccttttt ctgcagttgg agaaattaaa atgtattttc catcgccatt tgtacgtatt
      241 accaaagaat tttcctcaag aggtgtaggt gttacagcat ttggaaatgg atttcctgct
      301 gaatctgttg ttccgatcgt tccaatggat tcttttctat tccagaattc catacctttt
      361 ttggttagct ccatgatttt tttgttttca ttccaaattt gaagcgtgcc ttttacaagt
      421 tttaacacat caccataagc attaaaggaa gtttcgaata cttctgcatt tattgttcct
      481 actttgatga agtcagcaac aatttctcct tttgatgtga tagcaatacc gaacgggcca
      541 tttactccgt tgtctgaata acctaagcca tttaaattcc aacgccacac tcgctttgca
      601 ttcgccacat ttggagtatc catgataaga atctctgatg gagctttttc tggacgaaaa
      661 acgacatgcc caccagaatt accagtgatc catgccgtcg cattcaacac attttgaact
      721 aacgtttctg ttcgattgtc gattttcttt ttcaattctt gtgcttgagt atttactgcc
      781 gaagtgtaca gtgataaatc attacctaaa acaatatcct tatatttccc aagcgttggg
      841 aaataagtgt attcgaccat acgctctttt atctcgatat ctagctcttt cgccctaaca
      901 tgagcgacat caccaaagtg taaagacgct agctcttgat acatgtcacc gtattcgagt
      961 gtgtgttcca acgccaccat actgactgta tgagtagctt ttggctcatg gatacgatca
     1021 ttgtcaaata aggttttgcc ccatttgatc aattcatcaa ctgttttaca atctccgttt
     1081 tcacgtttgg caatacgtcg attctcgttg gttactccat caatttctaa ataaccatat
     1141 tcgataggtt ctttgtcttc atcataatcg ttatcaggaa caccgccaac caaatacaaa
     1201 ctattgacaa ttgattcttc atcaatttct tcttcgattg cttctaaatt gatgccaaaa
     1261 tcaatccgaa aaccattatc tgatccaatc tgttttacca gtttcaaatc atagttatcc
     1321 atatcaagtt ccgcgctagt cacgccagtc aaattttgat taccgttatt tgaaccaatg
     1381 attgcttcaa ctggcgcgac ttgtcttgct gtaaattggt gcgttgtccc tacattcgaa
     1441 agatagttaa atttttgatc aaatgccaaa ctgtttttaa gattggtcat gatctgagac
     1501 ccattgccgt tatccgtaaa cgacttgaca ataaagttct tattggccat aaaaccaata
     1561 tgccgagctg ttacagaaac ggaggtcaaa ttctttttga cattataaat ttcaaaatat
     1621 tgccatgatc catctggtac cttcgctttt ataaaatttc ctttttttaa ataagagcga
     1681 tactgtccgc ttcttgaata gttaccataa aaacgatatt ggccattcag cacacgattg
     1741 atttctggca aatcttccca atcaactaac gacgctccgt tcacgctcaa atcatctggc
     1801 atttttttat aagcataaat aaattcttgc gtcacagata cacactccta ttccaaaacc
     1861 gcacttcttt aaattttccg gatattttta cctgattcca ttcaggctgc aatactggcc
     1921 aatcaccacg cgtaaataaa ttcaaacctt cttgtattgc ttttccaagc tgagtatcaa
     1981 ccacgattgt tgcagctaac gtattaagta ttgttaggct tttatcaccg acagcgatcg
     2041 ttatatctcc tccgttcgat tctatttcca gatagggatg tgcaatttcg tcaccatgat
     2101 caaaaatatc cataacacta gaatgaaaaa ttttaggtgc ttcaccgatt tttcttttga
     2161 gtggctgaca acgaaaagta acatcgaatg tataaaagaa gccccactcg ttttcgaaag
     2221 ggacttcttt atccatgctg cagatagcct ctagatactt gtctggatca ttatgtgtga
     2281 ttaattggct tttaccagtg agccatcgtt tgacttctct cagtttcgaa tgtggaatag
     2341 tgatcccttc tatttccaaa tcaaaaggtt catagtcatc aaacgtctcc gtcaattctc
     2401 cgcttcggcc ctgaatcgtg taagtttcgt atcgcttgtt cggcataata tctggaagct
     2461 ctgcctcaat gatgcaattc atatcaatta ctgcattccg atttttccaa ataaaatttg
     2521 gttcatctgg attcataaat tgtcgactca aataggaaca cctcccaaat cacgaatagc
     2581 ctgtttgttt gctttagcaa atttacgatt catacgatct aactcagatg gattgtttgc
     2641 atcgactttg ccaatgtgta tatgctgttc aatgctacct ccagaaactc ttccactgat
     2701 ccctttgcgt ttttcttcgt ctgataatgg agtaactgtg gttttaccat tcttggcagt
     2761 cagtaactca ggtccagctt caccaacaat cgcttgtcca ttgattagat gaccgccttg
     2821 tgctaaataa ggcagttttg aaatagaaaa tgattttcca cctacaccag gaacccattt
     2881 tggtatcttt atattattca atccaccaat aaatccattg atcaatccaa tcatggcatt
     2941 aataggagct ttccctacag caacaatacc atcgaaaata cctccaaaaa tatcaactag
     3001 accttgccat gcttttgacc aattccctgt aaatactcca gtgataaaat ctagaaaacc
     3061 actgaaaatt cgttttccag cattataaaa attattgaaa tttgctataa caccatcgaa
     3121 aaatccacca aaataaccac ttaaaaaatt aaatatttca acagctacat ctgaaacacc
     3181 tttgaagaaa gaattcactc catcatgaaa ccatttaacg ttattatatg cccaaattag
     3241 tccagtaact aatgcgccaa tagctataac tgctaatgca aaccagcctc ccgacattcc
     3301 aaataaacca gcaagtcctt gccaaactcc tataaaactt ttaacttccc caacgatttt
     3361 tgtaacagat cccataagtg aaccaagaac gattagtact ggtccaactg ctgccgctat
     3421 accagcaatt gttatgatcc aattctttgt atcttgatct agagaccccc accatttaga
     3481 gaattcctgt aataaggaag ttgctttttc aaaaaaaggc aaaaggctta cttggactgc
     3541 ttcacctacg tcagccattg ctaattttgc attgttcata gcttgatcgg cttgatcaat
     3601 tgggtcgaga gtagcatcga atgtgtctcc tacagctccc ccactttctc cagcagtttt
     3661 tgctaaatct tccaggttca aagtacctct acgaattgca tcggccattc taggaccgcc
     3721 tttagtcccg aatacttctg ctgctgcatt gatggcttct gtttcagaac ctgcattttt
     3781 taccttgtct tgtagttctt ctagtccttg acttaaagat tttccgtctt tcgcataagc
     3841 cactgttgct ttagataaac tacttaaagc tgcgcttgaa tcaacaccag attgctcaaa
     3901 ttgtccaagt aaagtgaccc cttcaccaaa gctcaaccct aattgtttaa tttgtggtgc
     3961 gccatcaatt gctttttgca tcaagtcgtc tacagattga ccagtattct gcgatgtttt
     4021 cgttgttaca tcaaggacag aattcaaatc atcatattct agtccataag catcaatagc
     4081 ttgtcgagca gatattgctg attgcgaaac atctgtatca ttgatttcag cgtactgtag
     4141 gagataattg gttgaatctt ccagtttttt atccatgaat ccaaattgtg tatttacctc
     4201 accaatagct tccccaaccg tttgtaaagg taaatgagta tttgaaccaa cgtttttgaa
     4261 agactgtgaa agtctatcag cttgatcacc tgttgctccg gtttttgtaa tgatggtatc
     4321 aagtgcctcg tcaacttcac caaatgctgc aagtcctgct gctcctgccg ctacaatagg
     4381 cgcggttact ccaacagaca ttttttcacc aacgcctttt actttctcac ctgtttcttc
     4441 gattttctgg agtttttttg ctgtatcaac agaaacgtca ccttgttctt taagtgcatc
     4501 gttcgtctgt tctaatgctg tacgaagttt attttctccg gtttcagaat tgagtaattg
     4561 tttataaagt ttttctgatt cagcagaata ttcaccggtt tctttgacag atttttcata
     4621 ttcctctctc agcatttgag atcgttgttc agccaatcct aattgttttt ctaatttttg
     4681 tttagccgct cgcaattttt ctgtttgagt tgcatccttg tccatcgcag acacttggtt
     4741 tttgtactcg gcagcggcta agttcatttc tttgttgatt tctttgattg ttttcgaata
     4801 actgacttcg ccattcgttt taaaattaag aacgacatca gattctttac cagccattta
     4861 tcttagcgct cctttctacc accaaggcga tttatccata gttacagatt gaggtggttc
     4921 aaaatcggtg ttttgttgta accactgtaa ataagatttg agccacaagt taggtgtaga
     4981 ctttaaaaag aaactctcac tccaattcaa tagagtgaga gcaacgtaaa tataaaaact
     5041 ccaaggagtt cctatctctt ccgattcttt ttgtttttct ttctttttgc ttgcgctttt
     5101 tgaaagtctt gtggcttctt ggattttttt aggtcttcca cctgaaatgt ctggctagca
     5161 aaaatttcca tacaggtact ataagcagac aacacctctc cactcattcc caaaaatttg
     5221 aaaatagttt ctggatcttc ctctaaacca ccagtacgca gcatggcata aatcaaggca
     5281 cgcatgattt ttagatcact aggcgataag ttagcagaag aaatttgtcc ttctttttta
     5341 gatagcatgg cgttcatatc agattcaaat tgcgaataat ctccaccata cacatctgct
     5401 ataaattcca tcgtttgcat agtaaatgaa atagggaatt ctgcgccttg aataattaca
     5461 acagcagaat tttttaagtc ttcaacgtga attccataat cagataaccg agccattaac
     5521 ccgcacctcc aactttagcc aatgttttcc actgttcttc atcgtataca ggttgagcaa
     5581 tgaatttatt aaataattct agagaagctc cgtctctatt tgaatcaaaa cttgcataca
     5641 tcacattatt gtatttcagt ccgatggaaa ccagatttgc agttacatcg tcaatttttg
     5701 tttcttcctc tgcagtggca tactcttcgt caatcacatt ggatagttgt gtattaggat
     5761 accaaactgc ttttttaccg ccattttcaa tatttccaat aaatccaaag gcgaagtacg
     5821 gaaattctcg tgcggtattt ttgctaaacg ttactccgct tttagcaact aatcctttga
     5881 tttcatccat cacttctatc ggaataccca cgtgatccaa cgcaagttca tgttttgttt
     5941 ctcgcgacac acgacgaaac attttgctgg atgcccattt ttctaatgct gttccattcc
     6001 ctttgacacc gatttttgtg gcaattggca atcgtaaaac ttcactataa gtcggtgcag
     6061 ttccaacaga atctggcgtt gccatcatcg caattaaaat gtcgtccaat ccttcaaaat
     6121 aaaaagtatc ttgttttccc aattaaaatc acccttccca taaatcaagt atttttctag
     6181 tcataatttc ttcaattttt tctttgtttt gttcatacgt accacttgca aaatgttggg
     6241 cacgttgatt tgttgtgcca ttttcggcaa agcgccagta aaaggccgtc tcttcaaatt
     6301 gaactttcac ttgatcgttt tcaactacta cttttatttg atcgcgcata tgtttctttt
     6361 ttaagagcga cttaggaata ttaggaagca actgctttag ataaaagtta gctgcttctt
     6421 ctaaagattc caacgataat tttttcggat caacttttga aaggtttcct aaataatccg
     6481 atatttcaga aaaaccattc ttattacttg gcattttcca cacacctcac atatgtgtaa
     6541 tagttggtta cggtatcgtc gttctcatca ccttgtatac ctgtaaaatc tgaatatgga
     6601 atgccagcat tttgcagcgc ttgttcaata acaactaaat cctgttctgt tccaagtgta
     6661 aaaaaagaga cttggtaata aggtaatttt ttatagactt taccggatgc catttttttg
     6721 ctgttactca catttgagta cacaatgtat ggatacatcg tccctaatct ggctttgtct
     6781 ctgaacactg ctaactttgt tgatttcagc gctgttttca attcatcaaa gctaatcgac
     6841 ataagctaaa ctcaactcca tttctcttgc atcgggattc gtataaatgc gagtaatgtt
     6901 atacgttaca gaatcaattt tgagcgcact taatttctct gtgatggatt tatcccatct
     6961 gactttaatt cgtctgacaa cgtctgtctt ggcttgctgt gataaatatt tttcttgaga
     7021 agtcacaccg agttcttcat agaatattag acgcttaaat tcgtaaattg tagttggacg
     7081 atcgtttccg tctgttcctg ttttgatgtc tagcaattcg gctttccatc tgagattatt
     7141 agtctgtctc ttcggcattt tgaatcgctc cttgcacgat aaatggcgtc atggcattca
     7201 tagctttgtc gagttcatcc tctgaaactc tatattcata ggcaatgccg gcaaccatca
     7261 aaataagata ttcttgttgg ccaccagttg ctgttttgac ataatctttt gccatattta
     7321 aataaaaaga gagcaaagaa tcatccatgc cctcttcaaa atgaatatgt gatttgaatt
     7381 tttcctctaa agacaattct ttagtttgct cttccatctt aaccaccaac tggttttgta
     7441 atttcgtagc gatatactgc cggttcaaat ggagaataaa ccaattgacc atctagcaag
     7501 ttgtaaattt ggaatccaat ttgattttta ccagagaatt tttcaacaag tttttgaatt
     7561 tccaaggcac caataacttc ttgaatttta aatgcagaaa aatcgccaaa atataaaact
     7621 ggcgtgtctg gttcaccctt tttatctgct gcatctgtcc aatccacagg atagccaact
     7681 aattggtaac caattccacc ttctgcttgt gtgaatggcc gcaacaaagg aaatccatca
     7741 tctgttttca ttttttcaat ggcagtcaaa gcagctcgat taataataaa gcgtcccttt
     7801 ttcatcactt ctgtcactgg tgtattttta aattcgatta atgcatcata taatttttgc
     7861 ccagcacctg aagcagttag atctaaaggt tttttaaatg ctacagcctt tttggctaat
     7921 gcaccaggat tttcatttcc agcgtcatca ccattgaaca tataattgat ttctttacgc
     7981 acataagctt ttttcaattc ttccacaaca atatcttcaa ctggaacacc agacattttt
     8041 aataattttt tagttactgt tgccaaagca tcgaattcgg caggattaag caaaatttca
     8101 tcaaactgaa tagctgtttc agcaatatca gttgaacgct ctttcttgtt tacattcgca
     8161 tctgctttct tcacaagaat tggatatttg acatctcctg atgttcgcac cactgttccg
     8221 tatttacgaa gtaaattttc ttcttgagca taagtaataa cttcagatgc aattacttct
     8281 gggacagtaa ctgaaccgtt gccagcttca atccctaaag ctcgagcttc tgcttcagaa
     8341 atatttccag ctacaaaatt agcaaatgct tttcgtagtt gttgatcttt ttgtttcttg
     8401 gtcatttttg cacgtgcctc caatccgttc ttaattgatc caagtaatcc atctcgttgc
     8461 tgttgagtaa tcattccaga acgattttct gaactatctt cactgtctga atcttcttct
     8521 tgatcgttgt cttcaccaga acggctttcg tctgaatccg tactattcga ttgatcatct
     8581 gtattgtcgt ctgtttcatc agttccagaa tctgcgccta attcgtcttt aattccgttc
     8641 aattcatcaa taacactgtc aatttcttct ttcacggctt ctaaatctgc ttcgcgtaat
     8701 tctcctgatt caactttttc acgtaattca gtcaatcgtt gctcacgacg tgccttcatt
     8761 tttttcaata attctttatc catgtatttt tcctcctacg cttctagcgc ttgattaatt
     8821 tttttgatta atttttttct ttcttcgacg tttttttcta attcatcacg acttcttaat
     8881 gcagcttctg tatcttcgta tgctggcaaa ggcacaatag aaacctcgta taattccact
     8941 tcatggattg ttcgaagcat tggttcagaa ttgtagtccc acgtttcttc agtcggcaca
     9001 aaaccaaaac tacattggtt gatgtctcct cgttccatag atttaactaa gtcccttgct
     9061 accgttgtgt ccggtaaatc aacttcgaat ttcaaaccac gttcatcttc ttcaaggcga
     9121 agggttccgc ttttagtacg tcctagcaca ttggaccaat cgtgattgaa caaacaacga
     9181 acatccgaat tactaattgc ctttgagaat gcaccaggaa caatcacttc gcttaagtca
     9241 tcccataaaa gtgtttgact gttgaataca gcagcgtagc cgctaatggt cctcgtatga
     9301 gtttcttcat cggaacgtgt tgaaagattg gtgatgtcaa tcgtgcgaat ttccttcttc
     9361 ttcatttcca tcacctcctt tcaagtcttg atcattcgtt ggtaaggaat catctgttgc
     9421 atttttctgg ccaatcctag ataagtcatt tgaaatatag atagcttgtg tttctggagt
     9481 attctgttta ggaaaaccaa gcatttctgc cacgttatct ggacttgtaa tcccggtacg
     9541 aacgatgttg tagccaatat ttgtttttgt tgagtaagga acaaaatcca aaatattaat
     9601 tttccattcc actctatagc cagaattagg cataaaaaaa agagcggtgt aatgttcgct
     9661 cttgtttttc aatattggtt tgattgcttt gttgtgcaga tacatcatcg ctttttcaat
     9721 atctgtcttc atcagcgatt gatacgtatc aacattgatt cctagaaatt ttcctaagtc
     9781 ttttttgtaa acacctaaat aattcaaaat tgccgcgtca tcaacaggac tttttaatgt
     9841 ctcgatggaa tatccttttc ccaaaggaat catcttaaca gaatgatcac tctcattttg
     9901 cgttccttcc agttgatcca atatagcttt gacaattttt gtttgggcgc tattatttgg
     9961 attgatgtgg gcgtctagtt taagcatgaa cgcaagtaaa ccgcctttag tatatttgtc
    10021 cgtcaaaact ttttcagcgc tcagaacgcc ttctagagtg tttcttgcaa gatcaattat
    10081 tccagcacct tttaatgaat cagttccgat gttcttaatg tgtcgaatca tttgaccagg
    10141 tattttttga ccattcattt caaattcttc ttgaagtcgt tcattgattt tagttgttac
    10201 accgtacgcc aaatgaagct gatccctatc cgttaatggg aatgtctcac cattgatcaa
    10261 taaagtattt gtttccaatt tggtaaattc gaatcctgtc aaataatcat tgggactctt
    10321 caaaatattt agtaagtgat gatctttgac ttcgttgccg tcgggaccaa taacaattgg
    10381 tgtggccaat gccacctgat tagatatgtc ttgaactaat tcataaacat cagaagattc
    10441 catgatagat gaatccgtca catatctttg accataacgt gtgtagtgtc caaaaatatc
    10501 ctcgatatat ccacgttttt ccataaaaga atagactgca ttcgataacc gatcacgtaa
    10561 tttcaatttt tttcaccgcc tttctattta tctatagatg gaacttaggt aatcatctaa
    10621 ctcatctgaa tcaatatctg tcatttgatt catcgtttcc ttatgaccac acaaaaacgc
    10681 cacgaaccca tcaatctttt tctttgattg acgtttactt ggcgcttttt gtccattgat
    10741 gttagtaatt gctacaacgt tcaaagtgca ataaaggaat aatggattat caaattgaat
    10801 tcgtttctca taaaacaacc gttcgacatc gtcaaaagga gcattcaata ctttaggata
    10861 ttgagcaact tcaacgcatt ccaatcctaa gttttctaat ttctcaacaa gtttgtcact
    10921 catcgctgga tcataattca cttgctgaat atcatataaa ttcatgcagt cctctatgta
    10981 ctgcaaaatc tgatcttgat caatcatttt tccgtcgcaa aattcaacga aaccttgttc
    11041 agccaaatca ctgtaaggaa cattatcttc tttttctcga aactctaaat cttcattcgg
    11101 aataaaataa agttgcttta ctttaagaac cgctttacca tcttcatccc atgttgggaa
    11161 gtttaaagat acacaggtca aatctcgtgt acgtgataaa tctaaaccga tataacatgg
    11221 ttcgccactt aaatcaccaa gttcttgtgt ggtaactaaa catggctcta cttgatcctg
    11281 ttcaaagaaa ttatccgcgc cgttcacaaa tacatccaag tgtttcgtta gaaattcagc
    11341 tttggaatga gctgaccgtt gcgctgtttt aaatgccgat tctaaagcag ataaatcgac
    11401 tgatattccc cagttaggat tgcacatttc ccagactttt ctatccgtcc aatcataatt
    11461 tttatttggc tcatagatta gaacaaagtt tgaatcatta tcatcacgtt tcaacacttc
    11521 ttttgcttcg cgatatacac gcattccaac agacgacgaa cctttcccag cagttgagat
    11581 attaaacatc aatggctgtg gtaaagatat ctgagcagac ttaaaattgt catactgttc
    11641 cattttctcc tgtttatgca attcatcgtt caatacaaaa tatggattgg atccctcgat
    11701 attatcaata ttcttggttt gaacaataaa tttatttgag taagccatat cttcatgaat
    11761 atagtcataa gtaatactag aaacagttcc ctttggcccc ctaaatattt tagttccttc
    11821 aagtaggatt ggattgttta agattgtaac tgcaaaaggt ttggcagcat attgcgcttg
    11881 agcaaaatca gatgcgcaag catagcaatc aactgataac gccccttctc cgtacattgc
    11941 atatcctaat gaaccgacag caatcaatgt tttaccattc ttttttggaa tctggacata
    12001 agcctcacga gtaacgcgta caatttggcc tttttcattt tctttaaccc aaccataaat
    12061 ccaagaataa ataaattttt cccagggttc taaaagaaac ggttttccca ccatttctcc
    12121 ttttgtgtga acaataaatg attctaccca atccatcatt tcattcgcgc gatctacatc
    12181 aaaccaaata tcttttcttt ttttccactg ataccagcga tctattgcta aacgaacggt
    12241 cttaggatac ttcttaggtt tctttcttac ttcttttgca aataaatcag cataatttac
    12301 accaggttca atcatttttc agcacctgcc ttcttacgcc atttatttct gtgcgctgct
    12361 agttcatcta ctggctttac ttctgggcgt gtaatttctt catcttttct tgcggtcgat
    12421 cctccagcaa ttagtctacc agtttttgct ttgtttgtta atcctaataa atctagagct
    12481 ttcatcttct tatctgccca agtttctact tgttgtgcca atggatgttt tgattgatta
    12541 gtagctcctg atttattcgt gaatttttgc gtctccggaa atcctttttc cttccacaat
    12601 aaatatttgt gttggtaaat ttcaaaaata tccaagtatg attcgattaa tggatcaaga
    12661 gtgatggtgt acaaatcaga caaattcatt atttctaaga tacgagcttt ttcagcactt
    12721 actttttcat caataatcgc tttacgttgc gctttagtcg tcatttttgt atacaccccc
    12781 ctttgttttt tgaaaaattt gacctaacga tgcgcgtgac tccccgctac cctatctccc
    12841 cacgcgaaaa aattttgaaa atgaataggg gggcttcaat tgaaatacga aggaaaaact
    12901 tttttgtctt ccgtttcgtt ttcaacaatt ggatgacatt ttgaacataa tagcatgaga
    12961 ttgtttggat caagcttaag cagttcgttg tctttgattg gtacaatgtg atggacgtgt
    13021 gctctctttc caaatatgaa ctgaccacac cgctgacaat gaccaccttc tctttcataa
    13081 ataaattgac gcatatcttt ccatgcttgc gttcgataga atggtttgtt ctcatgatga
    13141 taaacagact ttgcttgctg cttcttcttg cgtgatctgc ttgatctctt gtgttcagta
    13201 cagtagatac cctttgctat tttgttcgtg catccgtcaa actgacagta tttcattcta
    13261 cttcacgaat aagatttatg atatcgcctt ttgcacggat agcaccagga atatcaatac
    13321 catgtttctt agcatatgca cgcaattctt ttgcagtcat attgtccagt tcatccgtat
    13381 cttcagtgga ctgatcatta gtagcttcgt ctccatcaaa attagcagca gtgtttccat
    13441 cgctatcaag aatttcactg ctatgagcta tgagttcgcc attgacagca acaaatgatt
    13501 tgccatcact caaaattcct ttttcttctt ttacttcaaa atttggttct tgatctttcg
    13561 gaacaactac tgtccttttc ttttctgaat cccaatactc tgttccacta atggatgttc
    13621 taattttgat cattgccatt ttaattctct cctttgtaat ttgtacggat tacttttgcg
    13681 cccattcgct cataccattc aatcgtttcc tgcagattgg gtagagtgtg tgacaataaa
    13741 gaaataacta acgtattcat tccagttctg taatcatcat tctccacttg cacatgtgca
    13801 tgattaccat tccaattttc tctgtacgga ctattctctg cttcaattgc tttcttataa
    13861 actttagcca aacttgattc tacttcaata ctaagtaccg cttcatgaaa atcattcatt
    13921 tgtttactct cctatcagat attttgtggt atgatttata aaaaagatgc gaggtgtttt
    13981 aatgcttcaa gaagttaata ttaagtatcg tgatcgtcaa aatacagaga caatttattt
    14041 gccaaatagt tgtccgcatt gcggaaatat aatgactccg tatgtgtatt ttggggtttc
    14101 atcatatagt gcgttcgata atgatagaat ctttggcgta ttagtacagt gtataaatga
    14161 tgagtgcaac aaattttata gtttacaatt tataaatacg tttaatgaag atgaaggata
    14221 ttctgaaaat attttaatta aagattatta ccgtccgccg attaaaatag atttaccaga
    14281 aaatattgaa aaagtttctc ctacatttgt tgatatttat actcaagcca cacaagctaa
    14341 atctgagcaa ttggaacaaa ttgctggagt tggttataga aaagctctag aatttctaat
    14401 taaagattat gcaatatcta aaaattcaga ggatgaagat aaaataaaaa aaatgttatt
    14461 aggtaaaaca attgaaaatt atttgaatga ttttcctaaa ctccaaagat tagccaaagc
    14521 tgctacttgg attggtaatg atgaaacgca ctatgttcgt agacatacta ataaagatgt
    14581 tcatgatatg gatgcattta ttaaatcagc agcgcaattt atcgcggctg attatgatgc
    14641 tgatttagct gatcaattta taaatggaaa taactttatg ccaactacta attaaaagaa
    14701 taaaagagcc acagatacca attaataaaa cggttgggat atcttggctc tttcatattt
    14761 ttttgacact aatagaatat catgctgcta acaatgttta catagctaca atgaccgaac
    14821 atttagtgaa cagtgtaatt ttagaataaa gagagttgtt ctttgtactt ctcgctattg
    14881 taaaaatcaa tttcgttttc ttttttcaat cggtcagctt gtctgtgttc atactcatct
    14941 aaaaagttca atgtctttct aatttctgca tgtcgctgtc tgacatacga tgagctatac
    15001 ccaacagatt cagcaatatc ttctaagctc atttgatcaa catatttcat cttaacaatt
    15061 tgattatcga taccagaaaa gctatctatc agcaataaca tttcttcttt ttgctcgatc
    15121 aacaattcca attcattttc tatcttttgg atattctctt ctaaagaaga agttctcgaa
    15181 ttcttttcga tgcggacgtt tgctaaatca ccacagaccc atcgattcaa ttcaagctta
    15241 cttttattaa gattccactt taagtaaaga atctgctcat ctagttcttg gtaatctttt
    15301 aaccaatgaa atctcacaaa cgccacccct tatggtagaa tagtattgcg ctgctatctc
    15361 gaaaggggta gcttttttat tttttcttag ccgttccatt ctggattgcc ttttgttcca
    15421 aacgtcgttt tttcttctta atctttgatt ttgtttttcc catacaattc tcctttccga
    15481 aaacacattt tgttcgattt ttaatactaa ataaaagttg gccagaattt ttcgttcgtc
    15541 tttactcatc tttttttgaa taagattact agcataaaaa tagttagtac cacgaaaatg
    15601 aacaggtaaa tcaattacgt tcaccttctt catgccagtt atcagccact agaatctttg
    15661 cgttagtgcc gccaccgttt tcttttttgt atttttcaaa tgctttataa gcagctgttt
    15721 ttgatttata gatttttccg gaaccgactg ggaacatcca tgtgccctct gtgatagcta
    15781 agatgtatac tttcatttaa ttcacccctt taatccccaa cactacatat ccggacttct
    15841 gcatgtaatc agtaatataa gtgatctctg ctttgtatga gtcaccagtg taactaaatg
    15901 ttggtctcgt tagtccaggt aattcatgtt taatgtattt tttatattca cgtagtatta
    15961 actgatcacc aactttgaag tcacgatcat tcttgcggat ctcgaattgt ttgcgtccgc
    16021 tcgtcactgc ttcaaaatat tctggtagta tttttagttc gtggatcatt ctgtttcctc
    16081 cttcaaaatt cgctcatcat caaaaagtga atctccacaa aatccttctc ccaaatattt
    16141 atcgttcatg tataagtcaa ccaaatattt gtgatctgct tctcgatatt cattaatatt
    16201 aacgatcttt attttgtaaa cattaccttc gtcgctcact atcttgaatt gttctctgac
    16261 tttcaccacc gttcctcctc tttttgaaaa aattttagtg tttttgtaag accccctaaa
    16321 tcagcttttt tatttgatat aatacttgta tcgattaatc aaatcgaaat taaatttaaa
    16381 aaggtgattt atcatgaata tcaacaattt agtaaaactc gttgaacaac gttttaaaga
    16441 atcaggatta gaacaattaa aaaaagataa ttctccagaa ttattttcta attttaccga
    16501 agacgacatt cctactctta aacaattaaa atattattct gattattgga cgcaaactcg
    16561 tgagaatgaa ttaaatttag aaaaactcat tattaaaaag aaatagcaac tccagcccac
    16621 acggctggtt ttttagtttc aacttccctc cttacgggtc aaaatcatcg gttccggcat
    16681 aatctgatca tcctttagca acaaatcagg atattttttc cttagcttct tattgttcgt
    16741 gtaagttttc aatagccatt ggttggcttc gcttttgctt tctccagaaa aataaatttt
    16801 ccctgtttgg atgcctgcaa gttgaatcat cattttcacc tcaaatcaaa ttttttctgc
    16861 tagatggagc aaaagcaatc cgacatcaag aatcttttga cccattattt cagctacttt
    16921 gctcggctta actccttgag aaaagagcaa gcgtgcttgc tctatctctt cgtgagtcca
    16981 aataaatttg gcttcctcaa ggataattac tggatcagtt gctctcattg ttcctctgga
    17041 aaaatgatgt cattcttatg cttggaccag gtatctgcat atggaacaaa gtattgtcta
    17101 gctaattcga tttgatcaat taaagcagtt tctgataatt catggtctgc agcaatttca
    17161 ttcatactat cgccttcatc taaacagata agaccgttga cgttatcgat ttttacattt
    17221 gtgactgctt gactttctcc acgctcataa tattctacag ttgatactga tacatcagct
    17281 tcggagttta attgcagaat ctgttactgc cgggataatt taatattctt ttcataattc
    17341 accttttttc ctactgacat cgaatatttt tcatgttatg attagccgtg aaaggagagc
    17401 tatattatgt gtttacacat gatgtcctta gctcattcgg ttctttggaa gcttttttgg
    17461 aaataactct caggttcttg acgcaaatct catttattct ttgaaacaaa aaacttccat
    17521 tttccgagag ctttggatca cttcaaaaga gatttgcatt tatatttctg tgaccttgag
    17581 tcgcgtaaag aaccttacag caatggcggc aattccactt tcaggaaacc gccttttttc
    17641 attgatattg gtggttagcg gactacccat tttctttcgg cagtgccaaa ccacaaatga
    17701 tctgtgttga tgtttaggta gttgtatacc agataagcta aatccaaagt gcctgcatct
    17761 tcaagacgac aatattccaa aaattctccc atagctggac ataaaaatcc tggagctatc
    17821 atatcccaac agttaatagt gcaaagaaat tcgtttagct tctgaacgtt ttctttggtt
    17881 tcacgaatta caacatactc caattcttct ccgctggcag agcattccaa aacttcaaat
    17941 tgattaagaa atggtagaac atatgcttca aacatcaaca ttccatcttt ctgtttttgc
    18001 acttgttttg catcaatcat gtctatcctc ctattcagtt atttcttcca ttaatggaat
    18061 tatttcaggt cactggactt aacgaaaaca ccattgacca tctttccagt ccgacctttg
    18121 atttcgtcat aagcaaaatc caagcactcg tataaatcca tatcattttg cattgccaag
    18181 atgatcaagg ttactactac atcgccaatt ccgtctctta aaccatgttc atcttttcta
    18241 gctagagaag cggcaacttc cccgatttct tcgaccgttt ttaacatttg cttgctgaaa
    18301 tccgcttgat ccaatccctt atcttttgcc cactgctcta ctttcgcgat tagttcgtcc
    18361 attatttctc ctccacatac ctaaactgtc ttccttttga atcaatccat aagctcctag
    18421 ctctatccca aataatattt ttgctcagac cagtaatttc agataactgt ttagcggtac
    18481 ccgttactag aattcgatca ccatgccaga ttgcaatctt tctcggcgtt ctccgtttgg
    18541 gcttttcagt ccacattgat ttaccgagct tttggacttc tgcaactatt tttttatctt
    18601 cctgccaatc ttctgaataa gtcaattcga taattcgctg cattgccgct ttcttatcca
    18661 tcccgacatt ctcctttcag taatttgagt acttgatcaa gtgcgctctc acgtccgcca
    18721 tgaaatgtgt tgagccactt gtcttcgtac gacacacttt gtcttaaagc ttcttgatgc
    18781 attaattcga tctgtgctgt aaatgtcttt aggtccatct tgtttacacc tgctcaagtt
    18841 cattaagatg tttttgcaag cctttaacac aatcaatgaa tagtaatttg gtatatgcta
    18901 aatttcttaa ttgcgttcca tcgatataga gtgcgaaata gtatctgagt ttactccaac
    18961 tcgaacgatc attcttaatt ccttcaattc cagcttcttc gagttgatca tatacgtctc
    19021 tcaggacgtc taattcctcg ccctttttat aattcgctat ttcattaatt agttctagat
    19081 aatcgatctt catttttcca cctctta
//
LOCUS       DBBGSZ010000043        18937 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.045, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000043 DBBGSZ010000000
VERSION     DBBGSZ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18937
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.045"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..435
                     /locus_tag="ACIZE5_002233"
     CDS             <1..435
                     /locus_tag="ACIZE5_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HGC6109349.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(759..842)
                     /locus_tag="ACIZE5_002234"
     tRNA            complement(759..842)
                     /locus_tag="ACIZE5_002234"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(806..808),aa:Leu,seq:cag)
     gene            1370..1870
                     /locus_tag="ACIZE5_002235"
     CDS             1370..1870
                     /locus_tag="ACIZE5_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6109350.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(2060..2404)
                     /locus_tag="ACIZE5_002236"
     CDS             complement(2060..2404)
                     /locus_tag="ACIZE5_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGC6109351.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(2539..3477)
                     /locus_tag="ACIZE5_002237"
     CDS             complement(2539..3477)
                     /locus_tag="ACIZE5_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGC6109352.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKNEESGLF"
     gene            3664..4155
                     /locus_tag="ACIZE5_002238"
     CDS             3664..4155
                     /locus_tag="ACIZE5_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HGC6109353.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(4179..6554)
                     /locus_tag="ACIZE5_002239"
     CDS             complement(4179..6554)
                     /locus_tag="ACIZE5_002239"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HGC6109354.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            6880..7506
                     /locus_tag="ACIZE5_002240"
     CDS             6880..7506
                     /locus_tag="ACIZE5_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGC6109355.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            7529..8233
                     /locus_tag="ACIZE5_002241"
     CDS             7529..8233
                     /locus_tag="ACIZE5_002241"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGC6109356.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            8425..9258
                     /locus_tag="ACIZE5_002242"
     CDS             8425..9258
                     /locus_tag="ACIZE5_002242"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HGC6109357.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            9455..11383
                     /locus_tag="ACIZE5_002243"
     CDS             9455..11383
                     /locus_tag="ACIZE5_002243"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGC6109358.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            11521..11976
                     /locus_tag="ACIZE5_002244"
     CDS             11521..11976
                     /locus_tag="ACIZE5_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HGC6109359.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            12056..12184
                     /locus_tag="ACIZE5_002245"
     CDS             12056..12184
                     /locus_tag="ACIZE5_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109360.1"
                     /translation="MFEKLKYFIGTIGWFLLAVLLILGLAYLLFPDLIQNVFDTAF"
     gene            12446..12715
                     /locus_tag="ACIZE5_002246"
     CDS             12446..12715
                     /locus_tag="ACIZE5_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109361.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            13115..13369
                     /gene="rpsT"
                     /locus_tag="ACIZE5_002247"
     CDS             13115..13369
                     /gene="rpsT"
                     /locus_tag="ACIZE5_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HGC6109362.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(13458..14504)
                     /gene="holA"
                     /locus_tag="ACIZE5_002248"
     CDS             complement(13458..14504)
                     /gene="holA"
                     /locus_tag="ACIZE5_002248"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGC6109363.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(14542..16815)
                     /locus_tag="ACIZE5_002249"
     CDS             complement(14542..16815)
                     /locus_tag="ACIZE5_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HGC6109364.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            complement(16808..17347)
                     /locus_tag="ACIZE5_002250"
     CDS             complement(16808..17347)
                     /locus_tag="ACIZE5_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HGC6109365.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            complement(17483..17701)
                     /locus_tag="ACIZE5_002251"
     CDS             complement(17483..17701)
                     /locus_tag="ACIZE5_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HGC6109366.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            complement(17698..17943)
                     /locus_tag="ACIZE5_002252"
     CDS             complement(17698..17943)
                     /locus_tag="ACIZE5_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGC6109367.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            complement(18059..18787)
                     /locus_tag="ACIZE5_002253"
     CDS             complement(18059..18787)
                     /locus_tag="ACIZE5_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGC6109368.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
BASE COUNT         5815 a         3666 c         3329 g         6127 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacctg ttcaagctga acaacctgtt
      121 gtacaagaaa cggttcaaac ggaaacacaa gcagcgcctg ttgctgaaac acaacctgct
      181 cctgctgtaa cagaaactgc tgctactcca gcaagtacaa gctctgcaaa agaatggatc
      241 gcacaaaaag aatcaagcgg ttcttacaca gcaacgaacg gacgttacat cggccgttac
      301 caattagatt cttcttactt aaatggtgac tactctgctg caaaccaaga aagagtagca
      361 gaacaatatg ttacttcacg ttatggttct tgggaagcgg cgaaagcatt ctgggaagca
      421 aacggttggt actaagattc attatttgaa cgtttaaaca cattcaaaat atagtaagag
      481 gtcatgcgat ttattctttc gcatgacctc tttttgagtt taagtttagt ctttattcct
      541 taactatcgt ttgccagtat ttcttgtatc agaatctata aatctactat ttgaatcaat
      601 ctattaggtt ttaaactgtc ccaccttcac acaaattttt tttgatttat ttgaatctgg
      661 ttccgttgtt taaaattttt cctatattct tttagataat atgttatttt ctttctcatc
      721 gctccaggtg taccttctct ttataaaaaa acaaattatg cggctaagaa gactcgaact
      781 tccacgaggt caccctcact agcgcctgaa gctagcgcgt ctgccaattc cgccatagcc
      841 gcatcacatc ttttagttta ggattacatg tgttttttgt caagaacata tttttgttct
      901 ttttcatttc tgtacgccct cccttatgcc atctacacaa ataattcatc cgagcaactc
      961 catcatctat tgagggttgg tgaaaaaatc tgttttatcc atatgatcga tttcaatgtt
     1021 aaacgaacga ctctgggatt agtaactatt ttattttttt cttcatttct tttttcctct
     1081 ttttctcgat tcagctatct tctttcattt ggatattgat tatttcttct gttgattact
     1141 atccttctgg aattctagac gctgaagtaa ttcacgtttt ctttcttcta gagatcataa
     1201 gtaacgaatg aacgaacttc aaataatttt tttattgtaa ttcatatttg tattgttcga
     1261 tgattcttaa tacgatatga cacaataaat aaaaataggc atggctattt acaacaatag
     1321 tgctatagta gaaaacaaat gaataaggtt acttaaagag gtgaatacga tgaaactgat
     1381 caaactatgg gaagcagatt taaagaaagc ttatcagcta caaactagct ttggaccaaa
     1441 tgagagtgga tttatcaaca atgcttatgg ctatacattt gctgaatttt tagattatgt
     1501 aaaaaaatgc gaaaaaacgt ctttaggaat cgatcttcct gagagttacg ttcccgcaac
     1561 cgtctttatt ttagaaagtg atgaacatga gtatgtagga atttttaatt tgcgccataa
     1621 actgaacgaa acattaagaa acggcgctgg ccatattggt tacggcatct cccctaatta
     1681 tcgtaaaaaa ggatatgcca cacaaggatt agcattagta ctacaagagg caaaaaaaat
     1741 cggcattgat gaggcacttt tgtctgtaaa taaaaaaaat cttggcagtc ttaaagcaca
     1801 acaaaaaaat ggggctgcga tttatcgtga agatgagaaa gaatactata cgaaaatcaa
     1861 actgatgtaa aaaagaagga ttccaaaagg aaagggattt gaatgtcctt tatcaataga
     1921 acacatttat ttaattaact tataatatag cagacaaaat tttataaaca aagaaacctt
     1981 ttatctcttt tcttctagaa aggataaaag gcttttttgt ttttcctatt tgcttctcat
     2041 agctagtcag ccaagatttc tatcgtatcc ccaacgcaat ccgtgcataa cggctcatct
     2101 tatctgtcgt ccatgctgga taccagacta gtttgacttc tgctttcgtt acttctggca
     2161 cttcttttaa tgcgtcatgg atagattctg ttaaaatatc tgctaatgga cagcccatag
     2221 ttgttagagt catcttaatg actgtttctc cattttcagg attgaattct atatcataaa
     2281 tcaagcctaa attgacgatg tcgattccta attcaggatc aatcaccatt tccaaggcag
     2341 caagaatacg ttctttgatt agttctattt cttgtccaga ccgttcttgg tttgcttcgc
     2401 tcatcgtacg acactcctta acacgatttt tatttatcat actctttttt tagctgcttg
     2461 taaatgagaa tttagaagta agattctcgt ttaaatttat aaaaatgttc ttattagatg
     2521 taatagatta aatttattct aaaataaacc tgattcctca tttttttgtg aacgattttt
     2581 tatttctggc aatacgccag ttgttcgata cattttttgt tcgttttcat ttgcaaaccg
     2641 gccaaatact gaatgagttg gtaaaatatt gataaatgca tcgtcgtcga tttcatgaac
     2701 gatctgatca agatcataca tttcgtagcg ggtgatgacc atcatgatca tgttcccttg
     2761 tttttttgaa tagccaccga cagacggcag taatgtcatt ccacgtacca tccgttttgc
     2821 tagttcttct gttacctctt ctggcttgac ggtaacgatc attgctgtta ctttttgatg
     2881 actcgtgtgg atggcatcaa ttacttgagt cattgcataa atggaaataa tcgtatacaa
     2941 ggcactttcc cagttaaaga agaagcctgc gatgactaca atgataccat ttagaatcag
     3001 catgtagttt ccgactgttt ttccagttgt ttgtgaaagt acaagagaga tgatatccat
     3061 cccaccagtt gtaaagccca tttttaaaga taatcctacg ccaagaccta ataaaacacc
     3121 gcctactagg gcattcatca aaatattatc agtgatctgt ccgactggaa gcagcatcgt
     3181 catcaccgat acacatacaa cattcacaaa actaaggatc gttgctcgtt ttcctacttt
     3241 gagaaaccct aatacaaaca cagggatatt caaaagaaaa ataaatgttc ctgtgtctat
     3301 cttgatatga aaccattcat ataaaagcga ggaaatgatt tgagcgatcc cattcatccc
     3361 tgcagaaaag acattggctg gaatcaaaaa ataatttaaa gcgaccgcag cggtcaatcc
     3421 ggttatcaaa ataaccacta ttttctttaa tctttcattt ttatgatacg cagtcataat
     3481 tttactcaca agcacctctc ccctactttg gtattccaaa tgtaagaata acagtttatc
     3541 tattaaaata aaatacttcg aactcaaatg agaagaattt tagcaaacag gtaagaatct
     3601 gccctaatcc tatgataaga tagatgtatg gtaaatattt atatgtatat caggagggtt
     3661 cctatggcaa aagatgctag cttcgacatt gtatcagaag tcaatacaga agaagtaaaa
     3721 aatgcgattc agcaaacaac aaaagaattg tccaatcgct ttgacttcaa ggattctaca
     3781 gtagaaatca aattagagaa cagcaatcta gttgtattga gcgatgatga tttcaaaatc
     3841 gaacagatca aagatgtatt atttggtaag ctgatcaaaa gaaatgtgcc aatcaaaaat
     3901 atccattttt ccgaatcaga acacgctcta ggtggcaaag ctcgacaaac tgccgatttg
     3961 gtcaacggaa tcgatcgtga aaacgcgaag aaaatcacta cagctatcaa aaatgaaaaa
     4021 ctgaaagtaa aagcacaaat ccaagaagat cagattagag tgacaggtaa gaaccgtgat
     4081 gatctacaag ctgtgattgc tttattacgt aaacttgact taccaatcga gttgcaattc
     4141 actaactatc gttaatcaaa aaacgaggct gacgtctgtc attcctcgtt tttttgattt
     4201 actgcttctt ttgataacca aaaacgctgt attccttctt ccaattcccc aacacttcgt
     4261 acttctcttg ctgtttgcca atgttgtggg aataaacgtc gataagaaaa actagaaaat
     4321 cgttgatctg ccaatacaac gattccttga tccgccatgc cacgaatcac tcgaccacca
     4381 gcttgcaaga ctttgttcat tccaggaagc tgataagcgt aagcaaatcc aaggtgttcc
     4441 ttctcatcat aatatgattt gatcagttcc tgctcatgat tcatctgcgg caaacctaca
     4501 cctacgatca tactgccgat caatcggtcc cctctcaaat cgattccttc tgaaaaaatc
     4561 ccgccaagta cgcaaaatcc aatcaatgtt tcagcgggat ttgtttgaaa ttttgttaaa
     4621 aatcgttcgc gttcttcctc attcatgtcc gtttcttgga ttagcacatt gctgtcggga
     4681 tattgctgtc tgaatgcttc caccgcaaga tctaaatatt gataagaagg aaagaaaacg
     4741 aaataattcc cgacctttcc atcagcaaaa gcatgaatcg tctctactaa ttttgccaga
     4801 ctgtgttccc tttttcgata agtcgtctct aggtaatttg cgatgaaaac ttgctggttt
     4861 ccttctggga aaggactcgg cagtttgtaa gccagacttt tttgtccccc cagtgtttcc
     4921 tgataataag agagtggtga aaaactagca gaaaaaagaa tactgctttt tcctttatcc
     4981 aacgactgct caagaaacaa gcttggatca atacaaaact cttttactat cagatcgcga
     5041 tacgtttttt cgactgttgt ttcgtagtga tcatcataaa attcactgac cttcaaaaaa
     5101 tgaagcaaat caaaataata aggaagcaat tgttcttgtg atgggtgctc aggaaattct
     5161 gccagccatt ctttaatttt ttcgcttaat tgataacctg cctttactaa agattcagcc
     5221 ggtgcttttt gatgatgata atcccaatga tcttcttttg ctatttctcg gatcgaatca
     5281 aattctttta atagtttgtt gaaacggcga tgaagttttt tgaattcctt tggtatagct
     5341 tccttacttc gtttcgtttt ttcataagat agttctgccg aatacatctc tcgggaacga
     5401 ttcaccaaat tatgtgcttc gtcaatcaaa aacagatagt cctcgttttt ttcatcttca
     5461 aaaaaacgtc ttaaataaac agttggatca aataaataat tgtaatcccc aatgattacg
     5521 tcacaccaga tactgacatc taatgatagt tcgaaaggac aaagtgtatg ctttcttgca
     5581 taagtttcga tgacttcacg agtgatctga ttctcatgat tcaaaagatc ccataaacct
     5641 tcattaatcc gattgtaata accattggca tatgggcact gatctggatt acaggtcgtc
     5701 tcatctaaaa agcagatctt gtctttcgcc gtcaaagtga cactttttac ttcagctcct
     5761 gtatctttta atgctgtcat agcatcttca gctacttgtc tagttattgt tttagccgtt
     5821 agataaaaga tcttttctcc ctcttcttcc cctacagctt tcaaagcggg gaataacgta
     5881 gagattgttt ttcctgttcc ggtaggtgct tctacaaaca atttctgttt cgtacggatc
     5941 gttttataag cagctaccgc tagttcacgc tgacctttcc tatactcatc atgggggaat
     6001 ttcaaagcca tcaaagaggc attgcgtaca gtgcgccagt tttcttgaaa aacaagccat
     6061 tctttataat cttcagtcag ctttttaaaa aaagtttcta actgctctct tgtctgatgt
     6121 tcaacctttc tcgtgatcac ttcttctgcc gtctggaagt aagtcaattg cagatttatt
     6181 tcttgtaaat catgttcttg actatagata taggcataca cccttgcttg atgaaagaaa
     6241 agttccactt gttctggttc taaatcttca aatcgtggtt cggaggtttt gatttcatct
     6301 atataataaa taccgtctct tttgaaaata ccgtctgcac ggccttcaac gatcaggtaa
     6361 tattcatcta attgaactgt tgtttttaaa aagacttctt tttcatagtt ttctcccgca
     6421 tctttttgga gcttgcggtg gattctcgct ccttctaatg cagtatggtt acttttttta
     6481 cgattgtcga tacttccacg tcgcaaaata aattctacta agtgccgcac agatattttt
     6541 gactgtttga tcatttccac cacctctttc tctctaagat tacctgaaaa aacctagttt
     6601 agcaaaaaga gctctctttc caaacataaa aaaacaccct gctgattagg cagggatata
     6661 ggatatagaa tttggatttt tggatgaatc taatgtaaca aggacatatt aaaatgctat
     6721 gaaaacttac tttccttctc tttagaatat ccaaatactt ttcatatagt ctgataattc
     6781 agataagtaa agagaaataa gtacctgttt ttgtttccta gcaatgaatg cgttatacta
     6841 atggatgaaa gaagttttgg ctatcaagga ggaatgcaca tgcatatcga aagattaaaa
     6901 acaggaatga ttgaagaaaa ctgttatttg gtctacaacg aagaagcact tttgatcatt
     6961 gaccctggag aagatgcgga acgaatcaaa caagaaatca aaaaaacaaa ccaacagccg
     7021 gtagcgattt tgcttaccca tactcactac gatcatatcg gtgcagtgga acctttacgc
     7081 gcgtattatc aaatcccagt ttatgtcagc ccactagagc aaaaatggct aggtgatccg
     7141 attttgaatc tttctggact cggtagacat gatgatattg ctgatgttat tgtctcgcct
     7201 gcagaatatg aatttgaaat gaaaacttat actttaggaa acatgtcttt tcgcgtcgtc
     7261 cctaccccag ggcattctat aggaagcgtc agctttattt ttgatgattt tgtcgtttct
     7321 ggcgacgccc tgtttagagg aagtatcggt agaaccgatc tgtatacagg gaatttagaa
     7381 caattacttc atagtattcg gacccagctg tttgtattac ctgatgaatt tgcagtctat
     7441 ccaggacatg gcgatgcaac gacgattgaa caggaaaaaa ggacaaatcc ttttttcaat
     7501 cgttaaaacg acttaggagg agaataaaat gacagaaact acactttata tcgtacgaca
     7561 cggaaaaacg atgttcaata caattgaacg agtacaaggc tggtgtgata cacccctcac
     7621 aaagcaagga caagaaggca ttcattattt aggtcgcggg ttaaaaaatg tcgacttttc
     7681 atttgcttat tctagtgaca gtggtcgtgc aatcgaaact gcccgtatta ttctaggaga
     7741 acattctaag ggaaaagaaa ttccttattt tattgaaaaa aggattagag aatggtgttt
     7801 cgggtctctt gaaggtggat atgacatgga aatgtggggt gtgatccctc gtgtattgaa
     7861 ttttaaaaca tatgatgaaa tgtttaccac agaagtttct tttgaacaaa ttgctaatgc
     7921 tgtatacaac ttagataccg ctgggtgggc ggaaacttat gaaacattgc gagaccgtgt
     7981 atggacagga tttgaagata tcgcccatca ctgcgaaaaa aatggtggtg gaaatgtttt
     8041 agtcgtatct catggtttga cgatcgcctt tttgcttaat ctgatcgatc ctaaacagcc
     8101 tgttcgtgct gggcttttaa atggcagcgt aacaaaggtc acttatgcaa acggtcgatt
     8161 ttctatccac ggcatcaatg atacgtctta tatcgataac gggaaaacac atagtcgcga
     8221 ctcgtttcta taatggggat attttaattt ttaccagaga atcataaaag gcaaagtctg
     8281 aacgagggct ttgtcttctt ttttctcttc gtgtacttat ctgctttatt tctcaagttt
     8341 ttcttaatat taaaaaacag attgggtttc tcaaaaaata acggtatact ataagatgta
     8401 tcttaattgg gaaggaagga atttatgttt tttgcaaata ttatcaaagc agtgattctc
     8461 ggtattattg aaggaataac ggaatggctg cccatcagta gtactggtca tttgatccta
     8521 gcagatgaat tcatcaaact ggatgccagt tcacaattta tgtcgatgtt caatgtcgtt
     8581 atccaattag gggcgatctt ggctgtcgtc gttctttatt ttcacaagtt aaacccattt
     8641 tctccaagta aatcaacggt agaaaaaaaa gatacgtgga cactttggtt taaagtgatc
     8701 gttgcttgca taccagccat catcattggt ttgcctttgg atgattggtt agaagcaaat
     8761 ttccacaagt tcttaccagt tgccattgtt ttgatcgttt acggtattgc ctttattatt
     8821 gtcgaaaaac gcaacaaaaa caaaacacct cgttggactt ctctgaatga ctttacgtac
     8881 caagcagctc ttcttgttgg gttattccaa gtcttggcac ttgttcccgg aacatcccgt
     8941 tctggcgcaa cgatcctagg atctatcttg attggtgctt cgcgttttgt cgctacagag
     9001 ttttcatttt tcttagggat tcctgtcatg tttggcgcaa gcggcttgaa gatcgtcaaa
     9061 tatttagctg aagggaattc attcaaaatg gaagaaactg ttgttcttct tgtaggaaca
     9121 ttcgtatctt ttgtggtttc cgtcttagct atcaaattct tactaagcta tttgaagaaa
     9181 aacgacttta ccgcttttgg ctggtatcgt attatccttg gtatcatttt gattggttat
     9241 tggtttattg caatgtagaa aaaaccagaa cacttctctt atttgagaaa tgttctggtt
     9301 ttttattttc tttaataata atcattataa ataataaaaa caacatcaag cttaatcacc
     9361 aaatgataac cattatcgtt ctcatttagc tgttattatt atcaattaca tttttattat
     9421 gctatccttg ttttgacaag gaggtctaat aacgatgact aatcagaaaa aagcttttgc
     9481 agcaacaatc ggctgccttt tatttatgat cttcggtttt atcttcgacc gattctctct
     9541 taccatcacc ccactttttt atatcagtgc cattatcatc ggtggatata aacaaacatc
     9601 ggaaggcttg aaagaattgt ggaatgatcg gacactgaat gtggatttat tgatggcttt
     9661 agctgctatt ggtgcctgtt tgatcggtaa ttactttgaa ggagcaatgt tgacattcat
     9721 cttttgttta agcggtgcat tagaggaata cacaactaat aaaagtcaaa aagaaattac
     9781 tgctttgatg aatcttcaac cacaaaaagc ccaattatta aaagaaaatg gacaaatgca
     9841 agaagtagat gtttctcaac taaaggtgga taacttggta tttgtcgcta aaggagcagc
     9901 tgttccgata gatggctttt tagaaagcac acaggcaacg atcgatgagt ctgcattaag
     9961 cggtgaatct gtgcctgtag aaaaatattt aggcgatgag atgtatgcag gaacgctgaa
    10021 tcaaggaaat cccatcacga ttcgagtaac aaaaacgagt tccgaaactg tctttgctaa
    10081 gattatccaa ttagtagaag aagcgcagaa tacgccaact caaacagctt catttatcga
    10141 acgaatcgaa aataattatg taaaattgat tttgcttgct gttcctctaa tgatccttct
    10201 cccccacttt ttcctaggtt ggagttggga tgaaagcttt tatcgaggaa tggtattatt
    10261 agttgtggct tctccttgtg cgcttgtcgc atctgctaca ccagcttctc tagctgctct
    10321 ttcaaattct gcaaaaaatg ggattttaat caaaggcggt atccatttag aaaagctttc
    10381 tgaattaaaa gcgattgcct ttgataaaac aggaacgctc actaaaggaa aaccagttgt
    10441 aactgacagc tttttctttg atgaaaagga tttggcacaa caacttcttg ttgctatgga
    10501 acaaaaaacg acgcatccac ttgctcatgc gattttgcaa tatttcgatt gcacaatacc
    10561 tgaagaaatc caatacttac caatagaaga aattactggt tttggattac aaactaccta
    10621 tttaggtgcg caatggaaag ttggcaagca cgcatatgat cctgagacga tgataatcag
    10681 caaagagatt gcggaaatga tcgaacgttt ggaaaatcaa ggcaaaaccg tgatttatct
    10741 ttctaaagat cagcagttaa ttgctgtttt aggtctgcta gatattccaa aagcaaatac
    10801 ccaacaagta atttcctact ttaaatccca aaacatccat acaagtatga taaccggcga
    10861 ccattctggc acagcaaagg ccattgctga acaagtaggg attgaacatt actatgcaag
    10921 ctgtactccg gaagaaaaaa cacaactagt caaaaaagag aatgaacttt accaagtaaa
    10981 tgcgatggtt ggtgatggag tcaatgatgc gcctgcttta gcagccgctt ctttaggtgt
    11041 cgctatgggg caagggacag atgccgctat ggatatcgca gacatcgtct taatgaaaag
    11101 cgacttaaat aaatttgtct acagtcatcg gctatcttta aaaatgcggc ggatcatcaa
    11161 acaaaatatt attttttcga ttcttgttat tctcttgttg attgcttcta acttcctgca
    11221 atttttaaat ctacctcttg gagttgtagg acacgaagga agcacaatat tggttattct
    11281 gaatggcttg cgtttactaa gacctttacc tgatctttct gattcttcaa aaaaatgtaa
    11341 gtcttgtcca ctatacaaag cgcggctgtc ttctgtcaaa taagcaaagt gtttttttat
    11401 gattttgttt attttatgaa aaaaacagct tatgaatagg tcttgaagga tgaattccta
    11461 cttttgtaac tttctaaaaa catgttatga ttgtttcgaa gaaagtgagg aatatatttc
    11521 atggaaagtt ggcttttttt aggaattatt ttacttgtag caattttagc taaaaatcaa
    11581 agtctgatga tagcggcagc ttttgttttg attatgaagc tcataccagc ctcccgttcc
    11641 tttttccctt ggcttcaagg caaaggaatc aatattgggg tgacgatcat cacagcggct
    11701 attctaatcc ctatcgcaac aggagaaatc ggtctacgtg atctattaga agcctttaaa
    11761 tcccctattg gctgggtagc tgttttttgc ggtgggctag tggctgtctt atcttccaag
    11821 ggtgtaggat tgattgcttc tgatccacaa atcactgttg cacttgtttt cggcacgatt
    11881 ttaggtgttg tcttcttaag aggaatcgcc gccggaccgg tcattgcttc tggtatcact
    11941 tactgtatct tacaagtatt tgctttagga aaatagaaca aattttgtct attttaggag
    12001 attcttaaca cccccaattt actgatccgt gatatactga caacgaggtg atacaatgtt
    12061 cgaaaaatta aagtatttca taggaacaat cggctggttt cttctagcgg tacttttgat
    12121 tctgggctta gcttatctat tatttcctga tttgatacaa aatgtgtttg atactgcttt
    12181 ttgattgacc tattaaaacg atatagggga tgctcctgcg atgcaggggc tttttttaat
    12241 caatgttttg taataattta ggccgtgcca atgagacttc ctatagaatt cgatgctctt
    12301 ttttcttttt ggctcttctg ctcttttttg ttatactaga ttacagtgga caaaagaaag
    12361 aatgatcgca tccacttcaa cgaatatcaa aatggaagaa ttagtgcctg ttttcaggtt
    12421 actttgaaaa gaaaggaaga cgcttgtgga aacttttgaa ggtcttttaa ttgatacgta
    12481 cgttttacaa gaacagccaa tgatgctgac tgggatcaac ttgcagcttg aggaccgtgt
    12541 gatcaatggc ctgcttaaag atcgctattt ggcaaaatat atcttacgtt tgcccctaaa
    12601 taaatatgtg ctggaagtaa gtggcaaatg gaaccgtcgg aaccagttgg tcataaaaaa
    12661 aatgttgata aaaaatatcg atgaatacat taaaataatc ggtacaccag aatagccttt
    12721 actgatcaaa ggatactggt tataaaataa ctgcagtttc ttaatagaaa aacaaagaac
    12781 aacagggaat cgtatccctt ttcaaaaaaa actttgcaaa cggttctctt tgttatataa
    12841 taacttagta ccaaacattc ccattcaaac tttgtttaaa tagataaata aaaatctagt
    12901 ttggtttgac gctattgcct cccacaatag cgtctttttg atttttttca gcttgtacta
    12961 tccgttttta ctgaaaaaaa atcctaataa aagactgtta aggaaaaaaa cttgtcatgt
    13021 tcatattgca aagcacgctg cctttaggta taataatgaa tgttgaatta tgcggtaaca
    13081 cgcgtaagaa cttaagttat cggaggtgaa actaatgcca aacattgaat ctgcaatcaa
    13141 acgtgttcgt acaagcgaaa acgctaatgt gaaaaattca tctcaaacaa gcgctatgcg
    13201 tactgcaatc aaaaaatttg aagatgctgt agcttcaggt gctgacaacg tagatgcgtt
    13261 atataaagaa gctgttaaag ctattgatat ggctgaatca aaaggtctaa tccacaaaaa
    13321 caaagctaac cgcgacaaat ctcgtttaag caaaaaaatc gctaaataaa agaatcggct
    13381 tcggccgatt tttttatttg tcaaaaaaag gacaaaaaca aacgaccttc ccgcatgctt
    13441 tgccctcgtc tttcttctta tcgatttctt aacaactgcc ctgtgcgcaa aacgaatagt
    13501 tgaaaactta attctttttc gatttgtccc gttttgattt gataatccat ctcaactaat
    13561 tgatcaaaca actgtaccag caaatgttca tcgaattttt ttacttcctg catggcaagt
    13621 tttacacgat atggatggat tttcaatgtt tcagcaatat ttgcctgctg ataaccaatc
    13681 tttacaagaa attttgtctg taaaaataaa cgtaattgag aaagcaaaat cgcattaatt
    13741 ttgattgttt cttccccttg cataactaaa tcttcgtata aacgcaaagc ttgttccgtc
    13801 ttccctttta aaatatattg ggtcatgtca aaaatattat gttctaacgt tttaggaact
    13861 aattcttcta cttctcttac cgtgatttgc tgttgatttt gtccataaag gaccaatttc
    13921 tgtaactctc tcatcatttt ggataaatct aagtcggtca acctcaagaa taaatcaatt
    13981 gcacttcgtt ccattttgat tgaggaattc tctaaggtat tcatcagata ttgacgtact
    14041 tctttttcat tcaactgttg gacattgatg ataattgctg tttttttcaa ttgtttcgtt
    14101 acttttttcc gttcatccaa cttttcatat ggcgcaaaga atactaatac agtcgattct
    14161 aatggttctt tcaaataagc cgtcaataaa tcagtatttt gttcgattcc attgtttact
    14221 ttttcacctg ttaaaaaata aggattctct acgaatacta accgttgatc tccgaaaaac
    14281 ggcaacgtct ctgcttcagc tactacctca tctaaacttg cattttccat gtcaaaactt
    14341 aaaaaattta agtcatcttc gccctctaat tggatttttt tgacaatttc tgtccgaact
    14401 tgatcttgga gaaacttttc tgttcctaaa atcaagtaac aagatgcaag tttttcttta
    14461 cgtatttttt gtaactctgc ttgtatactc aaattactca ccactttcaa aaattatcct
    14521 accatgagca gatgagaatt actagtctat cattgtttcc actagcccat gaggatgaaa
    14581 aactggatgc cagcgatagg tgatcattcc ttgttgatcc gttcgccatg tttttatctg
    14641 attttcttct agtgtctcca atacttcgct gtgcgggtga ccataacgat tatttacgcc
    14701 gcaggatata atcccatgtt ttgcttcaat atgggaaaga aaatctgtgt tacttgacgt
    14761 acggctaccg tgatgaccta atttgactac atcggctttc agattaggat aaatcaaaag
    14821 caattgtttt tccattgctt gattcaaatc tcctaaaaat aaaaagcgcc tattgttata
    14881 ttccatccat agaccaatcg aatcttcatt tcttccctct cccttttcaa aaggagtcaa
    14941 tacataaaga tcataataac cgctgatcct gtccccatgt ttgatttcaa tgatctcagt
    15001 accatttttt tgagcttcag ataaatgcct ttgtaatggc tcatttcgtc cagcgcccca
    15061 accgatataa atttttttga tagtaaaatg ctgagataac gtgggtaatt ctcccacatg
    15121 atccgtatcg tcgtgtgtca agatgagttt atcgattaca cttatcccct gaccttttag
    15181 atatggaacg atatttcttt cagcaggagg acgtatcata ccttgcgccc acttttctct
    15241 ttcaaagtgt aactgacctc cagtatcgat caaaatcgtt tcttttcgaa aaggactttg
    15301 caaaaagata ctgtctcctt gaccgacatc gataaaagcg atcgttgaag aaaagcgtaa
    15361 aaatggcaaa gtcaaaaaaa taaaagaaaa aagaccaaca taaaacaagt gtttcacagg
    15421 ttgttctttc aacctatcca tacaaatcag taatccgaaa atatacatcc cagatagcac
    15481 aaggggcaaa cgtcctataa tgagagacga ccctgaagaa aaatcgatta ttcgctcaaa
    15541 taagattaat ccctcttcta tcagcaaaag taaagtttcc ggcagccagc gattgaagag
    15601 tgtgagaaat aacacaccag gaagaaaaag aaacttgaat accggtgcaa tcagtaatgt
    15661 aaaaagacta cctaaaatag gccactcata aaaatgccat acaatcaacg gcatcgtgat
    15721 catagtaaac aggacgtgag aggccgtttt tttcaaccaa tctccatcaa aagaaatcag
    15781 gataaacaaa aaactcatga aaaaactaag ctgtccaccc gcatgaaaaa gaaatcgagg
    15841 atcaaatagt aaaagaagcc aaaagacaac tgcaaataag tccatggtgg aataatgctt
    15901 attcagcaat ttgactagca atcgcaataa aaacagcaaa ctagcacgca aaacagaaat
    15961 agaacttcct gcaatagaaa cataacagat agttagtaga ctcaacggaa taatactgac
    16021 gtgtagtggc catccgatac gtcgaaacaa ataatacagc caccctaaat aaaattggat
    16081 gtgtagaccc gatagactga acagatgcag caaaccactc tccctaaaaa tttcttctgg
    16141 ttctctgaat cctgcatctt tatagcccca taataaagaa ttaatatata cacttgtttt
    16201 ttgcggaaat tcagattgga caaaggagat aaaagatcct ctttttctct gaagccagtt
    16261 tcgccagtga ttttgcatgg tgatctgttc aatcttttga atttggaacc gtccagaaat
    16321 tctatggttc ctgaagtaag cttcttggtc aaaattataa agattccgct tttttgctgg
    16381 agagatgaac tcgccttcag cagtcaattc tattcccttt cctcggaagt taagccatgt
    16441 tttcaattct gcttctgtgt ttacttgata agaaagctgg agcttttgtt tattctctga
    16501 taaccttcct tccattgtca aaaaattacc atttgcacga atcgtatctg taaatacagt
    16561 aatttgcgca gatgttgttt tttcctctaa aaatgaatac tcttgtagcc tataagaaat
    16621 ggataccgtt atgctacaca aaatacacaa gtacgcgata aaacgtcctt cttttagcga
    16681 aaaccataaa aaaattccgg caagaagcaa acgataaccc caattgtcag tgtaatacaa
    16741 caaacagata atcatcgacg taattgccgg aaaaatcaac cgatttcgaa catgcctttc
    16801 taaaacgcta gacatgtttt cctgttaatt cattttgaag ttttgaaaaa tgctgtgagt
    16861 ctaaagcaac ttggtgtaca gatacaccta attgttcgat caacgcttgg gcataaggat
    16921 catttcgata gtcatggaga taattgatcc ctttcacacc agcttgcaac aaagcctttg
    16981 tacaggccaa acatggaaaa tgtgtgacat agatttctga accttccgtc gggataccaa
    17041 gttttgcaca ctgtaggagt gcattcatct ctgcatggat cgttcgcaag cagtgtccat
    17101 ccacgacgta acacccttca tctatgcagt ggacatctcc actgactgct ccattatagc
    17161 cgccagcaat gatccttttt tctcgaacga gtgtcgctcc tacttctaaa cgtgtacacg
    17221 tactacgtaa agataacagt actgcctgag ccataaagta ctggtcccaa ggaatgcgtt
    17281 cattatgtga cttatcagta actttttctt tattcgtatc gcatgctttt gaagattttt
    17341 ctaacatgtt ttatattcct ccgttttttc aagttgatta aaaagtactc attgcttaaa
    17401 caaaatattc tttaaatata acgaatcatc ctgtctgaca aaagatccta cccttcactg
    17461 ccgaaatgaa gtccgtcatc cattagccca ttataaaaat tcttcgaatc catttgttca
    17521 agaaattccg tataaaaatc gatacttcac aatcatggcg ttttgctact tctgtgagaa
    17581 cagagatata ttctttgatc aacttgttat tccgatattt ttgttttgtc tcatcgactg
    17641 ctggtggcgt gataaagaaa gcatgatcag aactatagtc ttttttcagc tgaactatca
    17701 tccactgcag attttttggt acgtttcttt agaaagttgt ttatgctctg ctagatcatt
    17761 cgtcccaatg agaataaata ctttatctgc tgtatagcta agtacatctt tggcaaagcg
    17821 ttctcgtaga gcttgactgt tattgccgct gacagccgta ttcataatat gaatcccaga
    17881 tattttattt tggagataga cattcagcat tggttttttt aatgtttctt tgcgaacaat
    17941 caagctattt cctatccaaa aatactacct cctcgtcctg ccaagctctt agaattggat
    18001 tattcttagt atccattagc gtccatttat tgctcgtgcc agtcgatttt gaatcattct
    18061 atttaattgt aacgaagttt tttagttttt caactgtctt ttcaccgata ccagaaatct
    18121 cctgcaggtc ttccactttc tggaaggatc cgttttcttc tctaaatcga atgatttctt
    18181 gcgctttgac tgatccgatc ccaggaatct gctgaagttc tgatggagtg gctgtattga
    18241 tatttatttt gggaggctcg gaatctgctg taggctgttt tccttccgag gatgccaact
    18301 gatcaagatg ttctggcagc tcttcaccta cagcagggat atataggact tgctgatctt
    18361 ctatcttcgc agaaaagttg attcgatcgc tatccgcttc ttctaataat ccacctgcac
    18421 gctttagtac atcatagacc cgttcttctg aagaaaagga atagatacca ggctccttca
    18481 cacttccttt gatatcggtg tacatgacct ttggacgagc atcctcttct acatcgtttc
    18541 cttcagctga tggatcttct ccactggaac taaacgaaga aagtatttct tttgcagcag
    18601 tctcttctgt ttctctataa aatagcaaat ttgataataa aaaaccactt gcgatacaaa
    18661 agataagaac tatcatagac atccaaatga tcaatttggg tgaagctagt attttcttgc
    18721 tgattttttc tatcattgtt cttttttcaa agaatgacca gtaaaaatca ttcattactc
    18781 ctttcattta aaattgaaga aacagtgagc tctggcaaaa tcgtcccttc aacatctaat
    18841 tacgtcaatt ttttcttttg tttttatttt tatcgtgaag atttttgacg aaaaagaggg
    18901 gttgtgacag aactcgtgtc acaacccctc tttaatt
//
LOCUS       DBBGSZ010000044        18909 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.046, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000044 DBBGSZ010000000
VERSION     DBBGSZ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18909
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.046"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(58..2157)
                     /locus_tag="ACIZE5_002254"
     CDS             complement(58..2157)
                     /locus_tag="ACIZE5_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division site-positioning protein MapZ
                     family protein"
                     /protein_id="HGC6109369.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(2377..3486)
                     /gene="rpoD"
                     /locus_tag="ACIZE5_002255"
     CDS             complement(2377..3486)
                     /gene="rpoD"
                     /locus_tag="ACIZE5_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HGC6109370.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(3510..5351)
                     /gene="dnaG"
                     /locus_tag="ACIZE5_002256"
     CDS             complement(3510..5351)
                     /gene="dnaG"
                     /locus_tag="ACIZE5_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HGC6109371.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(5533..7848)
                     /locus_tag="ACIZE5_002257"
     CDS             complement(5533..7848)
                     /locus_tag="ACIZE5_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGC6109372.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(8033..8893)
                     /locus_tag="ACIZE5_002258"
     CDS             complement(8033..8893)
                     /locus_tag="ACIZE5_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HGC6109373.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(8952..9584)
                     /locus_tag="ACIZE5_002259"
                     /pseudo
     CDS             complement(8952..9584)
                     /locus_tag="ACIZE5_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
     gene            9751..10512
                     /locus_tag="ACIZE5_002260"
     CDS             9751..10512
                     /locus_tag="ACIZE5_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC6109374.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            10538..13129
                     /gene="mprF"
                     /locus_tag="ACIZE5_002261"
     CDS             10538..13129
                     /gene="mprF"
                     /locus_tag="ACIZE5_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HGC6109375.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(13317..14504)
                     /gene="tuf"
                     /locus_tag="ACIZE5_002262"
     CDS             complement(13317..14504)
                     /gene="tuf"
                     /locus_tag="ACIZE5_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGC6109376.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            14872..15228
                     /locus_tag="ACIZE5_002263"
     CDS             14872..15228
                     /locus_tag="ACIZE5_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HGC6109377.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(15469..16473)
                     /locus_tag="ACIZE5_002264"
     CDS             complement(15469..16473)
                     /locus_tag="ACIZE5_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HGC6109378.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            16639..17490
                     /locus_tag="ACIZE5_002265"
     CDS             16639..17490
                     /locus_tag="ACIZE5_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGC6109379.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            17507..17752
                     /locus_tag="ACIZE5_002266"
     CDS             17507..17752
                     /locus_tag="ACIZE5_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109380.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            17939..18643
                     /locus_tag="ACIZE5_002267"
     CDS             17939..18643
                     /locus_tag="ACIZE5_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109381.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT         5353 a         3880 c         3333 g         6343 t
ORIGIN      
        1 tttttcgaat aaacggtgtt aaacggcagg ctcacagcct ctttcatttg cctaaaatta
       61 attgctccca tttcctccga accatccagt tttacagttg atggttacga tgtaaaatgg
      121 caaagcactt tctccaatgc ctttcatcaa tgcagatttt gttgaagtgg catatagatt
      181 ataatagcct tccccatttt cgattctggc tttttctaat ctgtaacctc cttcaacgat
      241 atatccacgt tggatacatg tagcaatcac tttgctttgg acacctggtg cccacgtcca
      301 tgctggatta gatgcatcgg caatatcact tgctctggca gatttgattg gctgattcgc
      361 tgagtttgaa gaggaagggg tcgaggatgc cgcttcttgc tgtgctgctt gtgcgaccgc
      421 agcttgttga gcggcttgag ctgcagctgc tgcttgagcg gcttgttttg cttgttcttc
      481 agctgctttt ttcgcttctt ctgctttttt cttttcctct tcttcttttt tctctttatc
      541 agtgagcatc ttatctactt gtttcaattg ttcattcaac tgagcagata gatctgtatt
      601 tttcactttt tctactgctt cttttgccgt cttgtattgg tcgcgtgttg ctgaatccac
      661 tacttttccg tctttaaaga ctatagctgt tttttcttta gctgtttgca attcagcata
      721 ttgattttta gcttctgttt gtgcttgttg aatcaatttt ccaaaatctg tgttatccgt
      781 ttcgattgct tggatctctt tatctgcttt caacttgatg tcatctgcta gatgatcatc
      841 gacgatggca ggtgctatga accactcatt cactttttgg atatctcgga tcttagattg
      901 gatatcttgg taagttgttt ctaactctga atatcctttt tcattcttaa gactggataa
      961 atcatttttt agttttgata aatcttgatg aatcatatct gcacgaataa attgatggtg
     1021 atcatctgta taaaaggcag caagtttctc atgaagttct tccatttgtt gctgtctttt
     1081 tgcttctgct gctacttcgg cttctacttt ttgatgatgg tcataataag cccagcttcc
     1141 tccaccgagt agaagtactg ctgctaaaac gagataaggt actttttttg attttttctt
     1201 ttgcgcttta tctggatctg ttttttctaa gtttgattct tgatgtgttt tttcagtatc
     1261 tggcacgatt gttattgatt tcgcttctgc ttcaaacagc ttaggctggt tctcttcttt
     1321 ttctattttt gcttcaagat cagtaccctc tttgcttaca gattgatttt cagcatcgga
     1381 ttcactattt atttcatcgg gctctgttga ctttttgtct gtgttttcga gtatttcttt
     1441 tttctctgct tccggcagtt tattcgtttt ttccttttct aattgttttt cagtaaatac
     1501 ttcagttttt tctgtgatat ccgtttttac gtcttttatt tttactgttt ctttacctgt
     1561 ggcgttttct ctatcagagt ctttttcagt ttcttgttcc ttttctggct ctactttgtt
     1621 ttcctgtgca attttttcac tgatcatttt gagcagctct ttcgcgtgct cttcttttgt
     1681 atcttcacga tgtgctttga tataagcgga tagtatcgaa ttttcttcct cattatcgac
     1741 gatttctttc agttcagcta ctcttctttt ttgttttgat tcaagcgttt cttcttgatt
     1801 ctttcctgat tcttccgaag tctcatgaac agttgctttc ttctgttcat ttttctctat
     1861 attagttact tgatcgtgag caggtggttc ttcgtcttct ggttctgctt tttcgaataa
     1921 ttccattaca gattctagag gtaaatcttt caattccgac cattcgattg gatcgtttaa
     1981 ttctgtatca ggaaagactg catcttcagt tgatttatcc tgcatagctg catctgtatt
     2041 tgtttcttca attgattctt ttatttgctg atcttctgca gttatttgat gaccgcagtc
     2101 tggacagata gtattctgct ccattttttt cgatccgcaa tttggacatt ttttcatcac
     2161 ttagcgatcg gctcctttac taggtttacg ctaccattta atctatcata ttctatacgt
     2221 cacgccaata gcttattttt aggatttact taaaaataat gaatgaattt ccttcctata
     2281 gaaaaaaaag cttgagactg cgtagtctca agcttttttt cttttaaaat aaaccaaaca
     2341 gttttactga tttctcttct ggtcaatagt ccacgcttat tctaagaaat cttttaattg
     2401 ttttgaacga gaaggatggc gcaattttct taatgcttta gcctcgatct gacgaatacg
     2461 ttcccgagta acaccaaata ctttccctac ttcttccaat gttctcgtcc ggccatcatc
     2521 taaaccaaaa cgtaagcgaa ggacattctc ttcccgatca gtcaatgtat ctagtacatc
     2581 ttccaattgt tcttttagta actcataagc tgcgtgttct gctggacttg ttgcttcctg
     2641 gtcttctatg aaatcaccta agtgagagtc atcttcttca ccgattggcg tttcaaggga
     2701 aacaggttct tgcgcgattt tcaagatttc tcggactttt tctgttggaa gatccatttc
     2761 cgcaccgatt tcttctggcg taggttctct tccaaggtct tgcagcaatt gacgttggat
     2821 acgtatcaat ttattaattg tttcaaccat atgaactgga atacggatcg tacgtgcttg
     2881 gtcagcgatt gctcgagtga tggcttgacg aatccaccat gtagcatagg ttgaaaactt
     2941 aaatcctttg cggtagtcaa atttttcaac tgccttcatc agtcccatgt ttccttcttg
     3001 gatcaagtca aggaactgca tgcctcgtcc tacataacgt ttagcgatac ttactactaa
     3061 acgaaggttt gcttctgcca gacgctgttt cgcttcttgg tcgccttctt cgattttcaa
     3121 tgctaacgct acttcttctt ccgcagttaa aagggagaca cggccaattt ctttcagata
     3181 catacgaacc gggtcattga tttttacacc ggttggcgca gaaagatctt ctgtttttgc
     3241 ttgttcagct tttttctcag cactcttcaa gctgtgaatt gatggatcac cattttcatc
     3301 caccacactg atacctgcgt cttcaatctt ttggatcaat ttgtccattt catctgcatt
     3361 caaagtgaat ggtgtagcaa gctgattgga taaatcatca tatacaactt gtcgtttggg
     3421 tttgttttct ttgatgaaag ctgctactgc tgcttcatac gtttttttat ctgttccatt
     3481 tgccataaaa gaaggccccc cttgagtagc tatttggctt gttttaactg tttcgttaaa
     3541 ttgatgattt caatcgtcaa ttcaagctca agctgtttgt ttccagttcg tctggcttct
     3601 tgctgcattt gtttttttaa tgttatttca tcagctaagc cagatttgct gatcacatct
     3661 agcaagtctt ggatttctcg tggcgaactt tcttctgcca ccggtaaata ttcgatttcc
     3721 accaccaacc gccttaaatt ttcatcttgc aaaaagtcta aaaactctgc aaggttgaat
     3781 tcataatgtt gtgagacata tgcatcgaat aaaaaataaa cttctgcata tgcatcatga
     3841 ataaactgaa attctcgttc ttttaaaata ttacggacag aaacttcttt aaatgcacga
     3901 tataatagaa tctgctctgc cttttctact tgcgtcaaag gtctcttttt ccgtgcagtt
     3961 tcttgtctcg taacctgagt gtgttgactt tcctgaggtt cttgacgatt ttgctgattt
     4021 gtccttcgaa gatcgcgcag ttgtttttgt atcgtctctc tgccgatctg aaactctgtt
     4081 gacagttgag atagatacat atcttgttcg attggtgaaa caactcggct aagttcaact
     4141 agtaattctt cgaggtattc gatcttgtct ttttcattat ctaaattttt cccttgtttt
     4201 aaataacgtg atttaaaagt aaagactgtt tcgcgcccat gagccactaa ttcttggaaa
     4261 gatgcttctc catacttacg gagatattca tcaggatcaa gcttttctgg aacgactacg
     4321 acagaaagtg ctaatcgact gttttgccga agcaattcaa tccctcgatt ggttgcttca
     4381 aaacctgcgt tgtctccgtc atagcaaaag accaattctt tcgtcagctt ttccatttgt
     4441 tggatctgtt gagctgttag acttgtcccc atagaagcta atccagtttt gataccagcc
     4501 tgccatgcag caatcacatc cataaaccct tcgaacaaca aaatttctcc gtttttccgg
     4561 atatcgcttc ttgctttatc aagattaaat aaaacttgtc ttttattgaa cagttctgtt
     4621 tctggactat tcaagtattt gggctgatct ttttcctgcc ctttttcagg tgcaagccag
     4681 cgtcctgaaa aaccgatcgt ctggccttga gaattacgaa gtggaaacat cactctttga
     4741 taaaaacgat cagacatacg gccatcatca tgcgtgacaa acaatccaga gcgttctaac
     4801 aattcatttg aaattgattc attcttgaat acttgctgaa gaaaagaacg ctcattaggt
     4861 gcaaaaccta tgttgaattc ttcaattaat tctaaagaca acccacgact ttgcaaatat
     4921 tctaaagctg gctgtccagc ttttgtatgc aatagcatgt gatgatagat ttccgctgct
     4981 ttttcatgag cagcaatcag tttccccgta gcagattcag gattttggac agctatagta
     5041 cgctgacgcc attgatcttc taacggtatc tgttcgaagt ctgccacttt taccactgct
     5101 tctggaaaac ttagaccttc tagttcttga agaaaagtaa acacgtttcc gcctttacca
     5161 caaccaaagc aatgaaaaat ctgcttgtct tctgcaacag aaaaagacgg tgtacgttct
     5221 tcatgaaaag gacacagccc caagtaattt ttaccagact ttttcaactg gacatattgt
     5281 ccaatcacct caacgatatt cgtttgactg cgtactgttt cgataacctc ttgaggaatc
     5341 cgttgagcca ttttttcacc ccctgctcta ttgatatctt ttgggtttaa cagaagatat
     5401 ttcaggagaa taaccggtaa aaaatcgcac taactgaaat cagtgcgatt ttaaaggaca
     5461 caattataca tgtttgattg tatcatattt cattgctttt tcaagtataa cacatttcta
     5521 tctcattaag catcaatttg ctactctttt cagtaactga ttttgaatat cagccttcca
     5581 gtacaatact cgaagaacaa tatttacgag catgaataca aagaagtatc ctacgctctc
     5641 tcccaaccct aagtttactt ccaaaattcc atggaacagc attgcagcta catatatccc
     5701 tacgatcgtc gttactgcta ggaagatgcg caatgggttg aagggataac aagcttttac
     5761 aactgccatg caactgatcc caatcagcaa gtaatacatc aaagtagtag tttcagcatt
     5821 tccccatgcg aatgtttttc caagtagata caccgcaatg atattcacta ctacaagcaa
     5881 ggcatttggt aaagcattaa taagtgctgt aggcaaataa cggtaagtga tttttctttt
     5941 atcttgttca aaagataaaa agaaggaagg atacccttca atcgctaaat caatcagcgt
     6001 gatttggata gggataaacg gaaatccaat tgctgtaacg gcacatataa tcgataaaat
     6061 aaatgaataa atcgttttga taaaaaagat gcctgagact ttcgtcacat tgttgaccac
     6121 tcggcgtcct tcaaacagga cttctggcaa tgtagtaaaa tcagagtcca acaataccag
     6181 attcgcaatc tgacgtgttg ctccatcacc ttctgccata gcaatgctgc aatctgcttc
     6241 tcttaacgcc aaaacatcat tcacaccgtc gcctgtcatt gcaaccgttc tgccgctttc
     6301 tttcaattca tttaccagca atttcttttg ctgcggactc actcgtccaa aaaccgtata
     6361 gcgatgagca gcttctcgca cttccatttc ttcagtaatt tgagaaagat cgacatacgc
     6421 atcataattc ggtaatcctg cacgtctagc gatattggag acagtaaaag gattgtctcc
     6481 agaaatcact ttcagatcca caccttcctc atgaagataa gctagtgttt cttgagcgtt
     6541 ttttcggatt ggatcatcga tttcaaacag agcaaccggc tcaacaaatg ctggtttttc
     6601 ttcgttcaat tgctgatttg gagcgatccc caacataagt acgcgatagc cattcgcttg
     6661 ggctgttttt agactgtccg gaagccgatc ttcttccacc aaacgttcag gcgctcctac
     6721 gtacacgact cccagttctg gaaattccat cgcgccccat ttgcgatcag aagaaaatgc
     6781 gactttgttt gtcacatcat accgattaga aagctcaaaa taatctctca tagcccgcat
     6841 agtgatgttg ttatcactgc tttctgccag atacgtcccc ataatttctg ggatggcttt
     6901 ctcgtacagc ggatgtagtg cttctacccg ctggatactc attttccctt cagtaatggt
     6961 ccctgtttta tccaagcata atgtatcgac atgggccagc gtttcaattg aatacatgtc
     7021 ttgaacaagg attcgttttt ttgccagttt ggttacccct gtcgttaatg caatacttat
     7081 tagcaatacc aaaccctttg gaagcatgcc taacaaagct gctgcagatg caataacaga
     7141 aattttgata gaagcatcgc ggatgaacag tgcttccaaa aatagtatga tccccaaagg
     7201 aataatcacg aaactagtga atttggatac tttgcgaatc gaatctacaa gttcagaacg
     7261 aatagctttg tgagtctttg cctcgctagt caagcggaca gcataattat ctgcacctac
     7321 tcggataact tcagccatga cagaaccgct tgtcaaaaag cttccagaaa gcaattcagc
     7381 tccagtttct ttgacaatca aatcagattc gcctgtcaaa agagcttcat ttgcttctgc
     7441 ccgtccagat ataacctgta aatcggctgg tatctgttct cctgctccga tttttaccaa
     7501 atctcctaat accagctctt tagtagaaat cgattgttct ttaccgtccc ggatcactag
     7561 tacttctgat tgggaaacaa tcgataattt ccgtacaaga tttcttgcat gtatttcttg
     7621 ataaattcca ataacgatat tgacgacaat aattgctaaa tacgccatgt tggaatacgc
     7681 acctacaaat aacagacaaa tcccaatacc aaagttcaga aaattgaata acgtcaatat
     7741 attatcgctg aatatttgtt ttgtactttt tgatgcatct tcctggtagt cattttgctg
     7801 gccagaagcc attttctgaa ctacctcttg ctgtgtaagt ccattcattt tctttttctc
     7861 cattttccgc caactttcaa aaataatcac gtgtttaagt ctagcgtgtt ccaagattaa
     7921 aaacaacttg tttttataaa atttatagaa aaacacacga atgattttac aaaaaagatg
     7981 ccaacctttt tgtttgaatc acccgtgtgc tgtttttatt atcaatctat ctttacttat
     8041 attgttcctc caaacggctc atccaccaac ctagtgctgt accggctata aaaagaacag
     8101 gacaagctag taccccagca actcccaatc ccgcgtaatc ggtaggaatg atcataatcg
     8161 ttgaagcaaa aactacacct aaaatgaaat ggaatagctt gctatatgcc tttgagaaaa
     8221 tgtaatccat gatttttgac aatccaagaa cacaaagaat cccaccaatt ccgatcggca
     8281 caatcacttc aagtcgtact tctttaaatc cgtcagccat cgctttatac aatcccatat
     8341 acaccaaaaa attagaaggg ctcaatcctg ggacgatcat acccaaacca atcaatccgc
     8401 cggcaatcag ccatgttcca aaattctgat cgacttgccc gtcaaataat tgagcgccgt
     8461 ataataaaaa caaataagcc agaacaaaag taacaaccat gatgatcaca tcagaagtat
     8521 ctcttccttt tttccctgct tctttccata acgcaggaac agttccagcg atacatccga
     8581 caaaaaacca taatatcgtt gtttcatacg cacctaataa aaaactgact aaaaaagaaa
     8641 gtagaaagat gcctgtcact ccgcctagac caacaggcag aaaaaacaaa acattttctt
     8701 tgaaattttt tgtaaggtgg gctaaaaaag aaatcagccg ctcatacatg ccaaagacag
     8761 ctgctaatgc accaccgctg actcctggca agataaatcc tgaaccgata aacattccct
     8821 tcacaaaccg taacatccag tctttggttg tgtaccccac ttcttgattt tccatttttt
     8881 gccttttttc cactatttgc gtactccttc tttcatttaa ttttattcat gattgaacat
     8941 ttcctgctat tttacttaaa gactttttca taggtctcta ttattttttc attcattttg
     9001 acaatatcag gataaaacat gttacctcca ttatgataga gatagccgcc attgtaaagc
     9061 aaggactgga tccgccaata tcggtattgt ttcccttcct catttcctaa aagtgggctc
     9121 agcacatctt tagaatacgc ttctgctaat tctactgtgt tttctccgcc atgatttttt
     9181 acataggcaa tataatcttt cccaaaatta tatgcttgga cagctgtcca taaatcgcat
     9241 ccttgtttct ttgcttctac tatcatttcc gccaaatatt tgacaccttg atcaatactg
     9301 tcagctggat tatcaatgat ctcagcttct ccatgcagac tttccgagct ctgcatgaga
     9361 tctgtccctt ttccttttga ttcggtcaat attatcgcct tgatcaaatt ctcgtagttt
     9421 tccatatgat aattttttgc agctgttgtt atttctattt gatagctttc cactcgtttt
     9481 accgaacgat aagttcttcc tcataaaaac aacaccgcac caataaccgt cagaatgatc
     9541 atgtaaaaaa gaatacggat aatagataat cgttttcgct tcatttcatc acctagttat
     9601 tttgacatct ttttttatct tactatttct ttatcttctt ggctatttct tccttgattt
     9661 ctgtgtacgc cttaagaaaa aatgaatttt cctgtatttt ttgacatctt acgaaaatga
     9721 tcgttgtttt tcagtaaaaa caattgccca atgactgata taatcgttat actttacaca
     9781 gtaggtgatt atgtgaaaaa agaaaagaaa tatgcaaaaa tgccagatgg gagcgaaatt
     9841 tactatgaaa agagcggtca aggcttccct ctctttttac tgcatggcaa tgacggcagc
     9901 ggccgctttt tttcagaaca ggtccctgta ctcgaacgct actataccgt gtatctagta
     9961 gatagccgag gacatggtcg ttcgacaaac gaagcatcta tgttgaattt tcagttaatg
    10021 gccgaggatc tgaatacgat catgttgctg gaaaaaatcg atcaggcaga ttttcttgga
    10081 tttagtgatg gagcaaatct agcactggta tttgccagca gcttccctaa aaaagttcat
    10141 cgattgattt taaattctgg aaacacgctt gttaaaggcg ttcgtttttc tgccagagtc
    10201 atcagtaata ttcattatgc atgggtatgg ttactctctt tatttcgccc aagtcttcgc
    10261 aaaaatcttt tagttatcaa acttttgctg catgacatcg ggcttacaga aaatgattta
    10321 aaaaaaatca actcccccac tttgatcatc gtgggaaaaa aagatgtaat caagctaaaa
    10381 cattctttgt atatagctaa aactatacca aaagcttcct ttgtgcttgt gaaagaacaa
    10441 ggacatgaat tagctagaaa agatcctgaa cgcttcaatc gagaagttct tcaatttctt
    10501 tctgaaacat aactattagg aatagaaggt gatttatttg ttaaaaaata ccatacaatg
    10561 gctgaaaaac cacctaggac tgttcaaaac aatctttttg atttctgtca ttgtcattat
    10621 tgtcggtgaa ttgatgtcca tcggtaaaac tctatctatc cagcaattag gagaaacgtt
    10681 tgccactata cctgtatgga aaagcggact aatgctattg attggtctta tctctgtgtt
    10741 acctatggtt ggttatgata ttattttgaa tcggatgctt gaacaaaagc agaatcctcg
    10801 ttacctgttt gagacaagct ggctgatcaa tacgatcaac aatattgccg gtttcggcgg
    10861 gtttgttagt gtggggcttc gctctgaact atatggacaa aagaaagaga gcagaaacgt
    10921 gatccaagca ttatcgaaag ttttcttgtt tttgatggct ggactttcta tttacagtct
    10981 gctttctttt ttacttgtag tcttcacgcc agttgctcct tttttgaagc aatattggat
    11041 atggttgatc ggcggcggtc tatattttcc tgtcgtcttt ttatttacta ctttcaaaaa
    11101 gaaaggattc cttggtggta cctcacttaa aactcaagga cagctattgc tagtttcatt
    11161 gttggaatgg accggtgtcc tgtttagttt cctttctgtt ggttatttaa tggaaatccg
    11221 gattgatctg tggcaaacaa ttccattatt cattgctgct tcagtgatag gaatcgtgtc
    11281 tatgattcca ggagaaattg ggagtttcga tgtaatgatg attatcgggt tgtccgctat
    11341 tggtgtgcca agagaaatag tcgttgtgtg gatcttgctc tatcgcctgt tctactacat
    11401 cattccgttt ttgattggaa tcgtcttttt cttcaaaaat atcggttcca cttttgatca
    11461 gcgttattct ggtatcccta aacaattagc aacagaaatt gcgcataaaa tcgtggttgt
    11521 cttattatac ttttctggaa tcatgctagt actttctgcc actatcccgc aagcttttac
    11581 agagtttcgc tggcttcata gtttgaaccc attgaaattt cattttatta tccaatttcc
    11641 tagtatacta ttgggatttc ttttaatcat tatgggcaga gggatcgcag cacgtgtgaa
    11701 acgagcatat ttgcctacaa tcttcttgat tgttctagct ttactttatg ttttattaag
    11761 tgattttagt ttcacaccgg tggttttctt gtctattctg cttctgatca ttcttgcttc
    11821 taaaaacgaa ttatttcggg aacaattgat ctattcatgg gagtggcgta cgatcgatgg
    11881 aatcattatt ggtgcactgt ccttgcttta catcgttatt ggggtataca atctgccgga
    11941 tttccctcat cggcgtcacc attttatttc ctttttctta tttccttctg aaaagatttg
    12001 gttttcggga ttgttggcca tcatcgctgt tagtttcatg atcgttctat ttgttcattt
    12061 ccttcaagga gaaaagaaac agattggcga agcctttaat gaagaaaagg ccctgaagat
    12121 ccttacaact tatggaggaa actccgatag tcaattgatc ttcttaaaag ataagcggat
    12181 gtttgcctat gaaaaagacg gtgaaccaac tgttcttctc caattcgctt gcttcaataa
    12241 taaatgtatt gtaatgggtg atccttctgg taagaaagaa gattttccag aagcaatcga
    12301 agcttttatc gaagaaacag atcgactatg ctatttacca gttttctacg aaacaagcga
    12361 agagattgtt atgattttgc atgaattcgg ctacgatttc attaagatgg gggaagaagc
    12421 ttatgtagac ctgaatagtt ttacaacttc agggaaaaaa atgaagggca ctcgtgctgt
    12481 cttgaatcgg atcgaacgag aaggatttac atttgatgtc ttacaaccac cattttctac
    12541 tgagcaaatg agtactttca aaaatatctc tgataattgg ttgggttcac gaaaggaaaa
    12601 agggttttct ttaggctttt tctctgaaga ttatctacaa agagcgccta ttgcagttgt
    12661 caaaaatacc caagaagaaa ttgtcgcttt tgcaacgatc atgcctactt acacgaacaa
    12721 taaagtagga acgattgatc tgatgcgata tgattctaaa aaagcacctt ctggcagtat
    12781 ggatttcttg ttcttgcatt tgtttgccta tatgaaagaa gaacatatcc aatggttcaa
    12841 tttagggatg gcccctcttt caaatgtcgg aacttccaga aagagttttt tacaggaaag
    12901 gattgcatac ttggtttacg agtttggttc tcatttttat tctttccatg gattaagaga
    12961 atataaaagc aagtacgcta caaactgggt ctcacgttat actctatatt ctagagatag
    13021 ttggattgca tatgttatga ttgctttgct gattattgat aatgcgccag ttgagcagac
    13081 acaaggtaga ataagtggtt tgaaaaaatg gatacgaaga aagtattaaa aactgcatac
    13141 cgatagatga acactctcat gatgaataaa agagactgaa gtaaaacgaa agttcatgct
    13201 tctacaatct cttcttatac aattgaagaa caaagagcgg tccaaacaga aatcctgttt
    13261 ggaccgctct tttattttaa acatttttca ttaccaaaat attcgagtcg cgtttcttat
    13321 gcttcgatct ctgtaacgat acctgaacct actgtccgtc cgccttcacg aattgagaat
    13381 gtcgttccgt tttcaacagc gattggatgg atcaagtcaa catcaatcgt cacgttgtca
    13441 ccaggcatga ccatttctgt atcttctggc aatgtgattg ttcctgtaac atcagttgtg
    13501 cggaagtaga actgtggacg atagttgttg aagaatggag tatgacgtcc accttcttct
    13561 tttgtcaaca cgtacacttc tgctttgaat tttgtatgtg gagtaatgga acctggttta
    13621 gcaagtactt gtccacgttc gatatcgtca cgttggatcc cccgtaacaa cacgcctacg
    13681 ttatccccag cttccccgta atctaacgtt ttacggaaca tttctacacc tgttacaact
    13741 gctttttgtg tttcaggttt gatccctacg atctctacct catcaccgac acgaacagca
    13801 ccacgatcaa tacgacctga ggcaacagtt cctcgacctg taattgagaa gacgtcttcc
    13861 actggcaata gtaatggttt atctgtatca cgttctggtg ttgggatata ttcatctact
    13921 gtatccatca attccataat agcagcttca gcatctggat cgccttgcaa tgcttttaat
    13981 gcggaacctt tgatcacagg agtgtcatcg cctgggaaac catattcgct caataactcg
    14041 cgaacttcca tttctaccaa atcgatcaat tcttcatcat cgactaaatc aactttgttc
    14101 aagaaaacaa tcaggtattt tacaccaact tggcgtgaca ataaaatgtg ttcacgtgtt
    14161 tgaggcatcg gaccgtcagt tgcagaaaca actaagattg caccatccat ttgtgctgcc
    14221 cctgtaatca tgtttttcac atagtccgcg tgtcctggtg catcaatatg cgcgtagtgg
    14281 cgtttttctg tttcatattc tacgtgtgcg gtattgatcg taatcccacg ttcacgttct
    14341 tctggagctg catcaatact agcatagtct tgaggatttg ctaggccttt tttgcctaat
    14401 actgtagtga tcgcagcagt taaagtagtt ttcccatggt caacgtgtcc aatcgtacca
    14461 atgttaacgt gtggtttact tctgtcataa tgttcttttg ccataattta caaacctcct
    14521 aaataatata gatcactgaa aaatttcagc tctcaccttt ttattatagt ctttttttga
    14581 ctaaatcaaa aagaatacgt ccgacttact ttttgtaaga ttcgaactaa gcttattata
    14641 cgtcaatatt ggtcaaagtc aactaagagc actcgtctgt cttatacgcg aaaaaagtac
    14701 cttttataaa taaaaaaatg tgttttttga gaaaaacttc aagatagtcc ttaactttct
    14761 tttgaagcaa taagaacaaa atgaggaaaa gtttaaaatt cagctgttgc caacaacttt
    14821 caatagacga aatcttctat ttcgttaata ataaggaaag aggtgaagta catgaaaaaa
    14881 ttaattggcg tacttgtcgt tttaggcata tttctcggcg gaagttttgc agcttatcat
    14941 tatttttacg gcggcgaagc ttattataca aaaatcacga cgaatggcga aatgtcagct
    15001 acccaagcag ataacggaga gaaattcacg acttatacct acaagcaagc ggcttataat
    15061 aaagatggtg aaaaaaaaca ggtgacgctt cgcgaagaaa gagaacatcc attaaagatg
    15121 aatgcgtatc ttaaactcaa agtcaatcct cgtaaaggtg tattaagctg ggaagaaata
    15181 aaggcttctg aagtgcctaa aaatgcggca gaaaaaatcg ataattagta aatggtctta
    15241 aaattttatt agataaaaag aggctgggac agaagcgttt aactccaaga aataagaagg
    15301 agttgcttct gcttccgccg tttatacgtg tttagagcgt gagacaaaag tgttctttac
    15361 ttttgtctca cgctcttttt ttgttatatt cgtcttttcc gatccttctc ttgacacaat
    15421 tcatttaact gatcactggt acttgaacac ctaatattct agtcattttt ataaacgatt
    15481 caatacttca tccacatttt tgatcatcac ggatatcgta ccatccggat tattcacaaa
    15541 ttcaatcaaa tctgggttgc gatatacatc tactggtacg atcagttcga tcccgtttga
    15601 tagcttgaat ttttgttttc caaatttttt ctcagaaatt tcttgtactt cttttacagg
    15661 aggtgcttct gggacaaatc cttgctcttg tacttcttct ttaaaagcca tttttgccgt
    15721 gatgttttcc ttgaagactt tttccgcaat catctcatga tccaaccgac ctttttcttc
    15781 tatcgtatca tagacagctt ctttcaaatc agccatgata tcaaattctt ctgtctcaaa
    15841 tttttttcca agatgcttgg ctactttttg gatcactttt acattttctt ctaaagaagg
    15901 tgcaggaaca ctttcgatca ctcttccaga aaaataaagc tcttttttgc cagaaaactc
    15961 atattttttt tcaattaatt cgtaggtcca atcagtcaaa ttcacagcga atgcttcatc
    16021 tgctttttgt gttttcgccc ctagaattgc tcgattcaaa atcaagcggt tgtcgatccc
    16081 tgcttcgtct gcttcaacaa agtgagtgta agcctcacga taattgactt tcaataaaga
    16141 taagtacatc actgtatcta attcatacaa gacaacaaat acatctgcac taggtgcttc
    16201 ttcactttct tggtagatat cgaaccaccg ctgaacgatt gcttcacttg cttccacaaa
    16261 attttcttga gcgattttaa gtgattcaac gatcatgctt tcttctgcta gttgtccagt
    16321 ttttgtttga gcagaagaga ttttttggat cttcttttga agaaaatcac gaatatattc
    16381 ttttgtcaga tccagctctt tttgtgaaaa gactggagaa ccagtttctc tgtcaataat
    16441 atgcagaatt gcttttttta aatagatatc cattttctca ttcccttctg tcttagttta
    16501 cggaaaaaaa atcaaaaata ccagaatcaa aatcattttc ttttaaacaa aaatttcaag
    16561 agtagaaaca aaatggattc tttttttcga aaaatgcgct acacttatag ttgaacgaat
    16621 aaaaaaggag ctgaaagtat gaattcatta acaagcactt atcgtctatc aaatggttac
    16681 gaaatcccgg tagtaggatt cggcacatgg caaacacctg atggggatgt cgctgtttcc
    16741 tctgttaaag aagcgctggc tgcaggttat cgccatatcg atactgccca aggatacaag
    16801 aatgaagaaa gcgtcggcca agcgattaag gaaagtggaa ttcctagaga agagatattc
    16861 ttgacaacaa aattatggaa tgcaaaccac agctatgaac ttgtgatgtc ttcttttgaa
    16921 gaatcattga agaagctcca aacagattat ttagatctgt ttttgatcca ctggccaaac
    16981 cctgttgctt ttcgtgataa ttgggaacaa gcaaatgcag atacatggcg agcatttgaa
    17041 gaactgtatg aagcaggtaa aatcaaagca atcggtgtga gcaatttctt accccaccat
    17101 ctagatacac tagcaaaaac agcaaaaatt atgccgatgg tcaatcaagt tttccttgca
    17161 ccaggcgaat tacagacaac tgtagttgag tatgcaaaaa aacatgatat gatcctcgaa
    17221 gcatatagtc cattaggcac tggtaaaatc ttcgatgtgc ctgaaatgaa acaaatcgct
    17281 gaagcacatg acaagacgat tgcacaagtt gctttgcgtt ggtcgctgca acacgaattc
    17341 cttcctcttc ctaagtcagt gacaccaagc agaatcaaag aaaatactga attatttgat
    17401 tttgaattaa cagaagaaga aatgaaacaa atcgatcagt tagatggtgt agtcggcaaa
    17461 gcaaaagacc cagatactac ccaattttaa gtcgaaaggt gattttatgg atccaatcga
    17521 acgcttgaat tctctctcgg aagaagttac ccagactttt cattccgatt ttgtcttttt
    17581 gatcgatgca gagaaaatcc aacattttcc tgcaagaaac tggacacatg atcaaatcat
    17641 cgaagaactg aaaaaacggt tcgatcattc gctaatggtc aaaccctggc acgaacatga
    17701 agtcatttat tcacctgaac tacctgtttt tgccttgata ccgaaaaaat agaaagaatg
    17761 gaacggatta tgtatatata cataatccgt tccatttttt atttttcttt caaaaaacgg
    17821 gaaaatacgc aaatttttct gttgtaattt gcgtatacgc aagttttttt gcattactcc
    17881 ttttcatttg gctgtttttt tcttataatc gaaagggtat gagcgaagga gagaacatat
    17941 gaagaaaaaa cagaaacaaa aattattaaa tcaattccgt ccttcattgg atggtgtaag
    18001 aggacaatta ttccgttctc tagaagaaga gagcttgcga cgttatggtt tgccgttaca
    18061 agtcatgctt gatcccaaaa accgtcaaat cttaacgatc ggattagctg ggaaaacaaa
    18121 tgaagataca cggatcaacg tgccaatcga tgacaacttc aatactgtat taaagagaat
    18181 tcgttcagga gaaaacggga ttttcgaacg attccgtgac aatcttctta ttgaaatcgt
    18241 gtcttactgg aatgatcaac gattgaaaaa cgatgaacca actgcgcaag ctgttgcgac
    18301 accagttaca gaagaaacag tcagtgtgcc agaagaaaaa acggaaaaac caaaagcgga
    18361 cacaactgaa aatacacgct caactgatac gaatgccgct ttaagttttg ctgatttttc
    18421 aaaagccgtt gctgagtatc ctaaatttta cacagaacaa aatgaacatg aagtagttat
    18481 taatgaaaaa aatgctgatg aacctcgtaa attagcaact atttctatga ctactgaaaa
    18541 tgagttcgtt atcgaaaaag cactcgaacg gaaatacaaa gtcaaattga ctttgattcc
    18601 tttgatcgaa caatttgcag cgacagcgat tactgatcga taaaaattct atttgtcata
    18661 aaaggctggg atttaaaatc ccagcctttt tagtcatata ataatttcta cagcaagtaa
    18721 aaagaaattc cttctaacat caggctcaaa tatcagcttg acctgtccaa caaatcacct
    18781 atgatcctac aatgttaggc gacttctctt ctacctgaag atatcttgga gttgcctgat
    18841 ttcttaagat gcctaacctt aactataaaa aattctaata ataaacatat tttctgatag
    18901 agaaaaaag
//
LOCUS       DBBGSZ010000045        18789 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.047, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000045 DBBGSZ010000000
VERSION     DBBGSZ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18789
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.047"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(510..1076)
                     /locus_tag="ACIZE5_002268"
     CDS             complement(510..1076)
                     /locus_tag="ACIZE5_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC6109382.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1076..2032)
                     /locus_tag="ACIZE5_002269"
     CDS             complement(1076..2032)
                     /locus_tag="ACIZE5_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HGC6109383.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2032..2688)
                     /locus_tag="ACIZE5_002270"
     CDS             complement(2032..2688)
                     /locus_tag="ACIZE5_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGC6109384.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3058..5076
                     /locus_tag="ACIZE5_002271"
     CDS             3058..5076
                     /locus_tag="ACIZE5_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGC6109385.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5146..5352
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5503..7917
                     /gene="leuS"
                     /locus_tag="ACIZE5_002272"
     CDS             5503..7917
                     /gene="leuS"
                     /locus_tag="ACIZE5_002272"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HGC6109386.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8265..9818
                     /locus_tag="ACIZE5_002273"
     CDS             8265..9818
                     /locus_tag="ACIZE5_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WD40/YVTN/BNR-like repeat-containing protein"
                     /protein_id="HGC6109387.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10199..11983)
                     /locus_tag="ACIZE5_002274"
     CDS             complement(10199..11983)
                     /locus_tag="ACIZE5_002274"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6109388.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(11998..13719)
                     /locus_tag="ACIZE5_002275"
     CDS             complement(11998..13719)
                     /locus_tag="ACIZE5_002275"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6109389.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13819..14580
                     /locus_tag="ACIZE5_002276"
     CDS             13819..14580
                     /locus_tag="ACIZE5_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGC6109390.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15547..15815
                     /locus_tag="ACIZE5_002277"
                     /pseudo
     CDS             15547..15815
                     /locus_tag="ACIZE5_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16487..>18789
                     /locus_tag="ACIZE5_002278"
     CDS             16487..>18789
                     /locus_tag="ACIZE5_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HGC6109391.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQLVET"
BASE COUNT         6178 a         3336 c         3781 g         5494 t
ORIGIN      
        1 tcttttttac tgctttgatc ataaaagtct gcatattcat cactgatatt ttttctaata
       61 aattcttcca tcataaaaat cacctcaaaa cgattatacg aacttacgtt cttgttgtaa
      121 agcgatattt gaggggcaaa aaaggggcat aatttgactg atattaagtt agctattgat
      181 atatgaatga catacaaaaa tataaaatct tttaaaaatg cttatatatc aatgtttttg
      241 ccattctttt atatatctgt tatatgtcaa aaaaatgtgt tcaatttcaa tttgtatttg
      301 aataaagagg ttgtgaaaaa gctgtcctgc atcaagtaat aagaacagcc aatcaaaaac
      361 agcttctcat gtttttgatt tggttggact tattaccgca gatataagct tttgagcacc
      421 gtgaataaag aggttatgaa atcaacgctc taacctgagt attagagaaa aaaacgcaaa
      481 acatatcatt tatgttttgc gttttttatt tatctttttt tctcaataca atataaaata
      541 ggcggctggt tcttttggtt gataaaccga taattcagca cattatatgt ttcctgtggc
      601 agtttggaac aaaaagaatc aaccatatcc agttcttttt ctccaccttc atgaccatag
      661 tagacgacaa ggatcaatcg tccgcgaggc acaagtcgtt tcaatatttc ttccatagct
      721 gtgcgtgtag tctctggcat agtgatgatt gctttatcac tttttgggag ataccctaga
      781 ttgaaaatcc ctgctttgag attttgttgt tcagctatca cttctcctaa cgtttcgtgg
      841 ccttgtagaa acaatgagac acgttcttct aactgacgct gttctagcct ttcacgagta
      901 gcatcgattg cttgttgctg gatatcaaaa ctatagacat gaccagtttt tccgatgtgt
      961 tctgctagaa aaaccgtatc gtggccattg cccatcgttg catctacgac gtgatcccct
     1021 ggttgcaaga tttcttgcag taatgtatgg ctgaaatgca aagcagtttg caacatcaga
     1081 cgctcacctt tttccgtaca tcatattttc cttggaagct atctctgcga agaagttctt
     1141 catcaattgc attcaagact tcccattttt tcaagctcca cattggtcca atcaaggaat
     1201 cccacggcgc atcccctgtc aaacgatgga tgatgatctc ttttggtatc atttccagct
     1261 ggtcgcaaat gacattgaca tagtcaggac ggctcattaa ttgaaggcga ccttcatgat
     1321 agtcccgcaa cattctcgtt ttgcgcatca gatgcatcaa atggagcttg attccttgga
     1381 tatctgaatc taaaatggtg cgtctgacat tttctttcat catttctaaa ctttcgcctg
     1441 gtaatccgtt gatcaaatgc gtacaaacac ggatattatg tttgcgtaat ttagccacgc
     1501 catctaaata agtttgataa tcatgtgctc ggttgatcag ttttgaagtt tcttcaaaag
     1561 ttgtttgcaa tccaagttct acccataaat acatccgctc gttcagttca gcaaggtaat
     1621 caactacttc atctggcaga caatccggtc gtgtaccgac tgataatcct acgacacctg
     1681 gtaaattgac tacttgctca aatcgttctt tgattatttc aactggcgca tgggtgtttg
     1741 taaaattttg gaaataaacg atgtattgtt ggacatgagg ccatttttga tgcatcatgt
     1801 cgatttcttt ctggaattgg attggaagag ggtcttcagg tgcaacgatc atgtctcccg
     1861 aaccagatac actgcaaaaa gtacaaccgc catgggcaac agtcccatct cgattcggac
     1921 agtcaaatcc tccatcgatc ggcaccttga aaattttccc gccaaactca tttcgtaaag
     1981 cgtaattcca agaatgatat cttttatttc cttctgaata aggaaaagtc attaaaagtc
     2041 cttctttctg taagagttat ctatttgttt tcttttttct ctatacactg gataagtcag
     2101 gcacagccaa gaaagactga gtaagtaacc gccgatgata tcagtaggaa aatgaacgcc
     2161 cagataaatg cggcttatcc cgacacttac tataataaac atcatcagca attgaagcaa
     2221 tgtgcgtaag gttctttttt gaacaaaagc tggaagcaga aatagtaaag aaccgtaaag
     2281 aatcatactg cctgctgcat gtccactagg gaaactgtaa cttgtttcaa ctactaagtg
     2341 cgccaatgaa ggacgctctc gcatgaaaaa tagtttgatc accgggttga tgattccagc
     2401 aattacaata aatccagaaa cgaaccaaaa tgtttctgcc ctttttttct tataccacat
     2461 ccataaagcc gcacaagcaa ataaaatgat gacggtaaga ggattaccga atttagtcat
     2521 aaagagttgg tagctgttca gatcaggata agaagctctg acaatgcctg taaaccactg
     2581 atcgaaacca gaaagccacg acagatggaa ctttacgatc cagcccaaaa tgaaaaacag
     2641 gacaagaaag aagctaccag ccacctgaaa tgatgtttta tatttcatac aattcctcct
     2701 ttgaagcaat gacttattat agcatttttg gtccagcgaa aaaaacggta aagagataaa
     2761 accaatgtat gattcctctt tgaataacca atattcttat aaaaaaaata actgtaatcg
     2821 gaaagacatt ttttggtaat gcaaatgaaa tgttagggaa ataaaatcag tgtttttcga
     2881 aatcctttta aacaagaacg tagacgtagg aagaacttga aaatgaacag aagttgttca
     2941 ttacggtaaa ttacaatatg attacaaaaa acaacaaagc tcttaaataa cttttaataa
     3001 atattaagag aagttataat tattaataat agataaattg aagttggagg atagaagatg
     3061 gaaaacattg caagaaaaga acggagacgt ttagaacaga ccaaacgttt tcgaaaagca
     3121 aaacgagggg cagcaatcgt gggaactgcg atggtaggct gttctgtcgc tgccccatta
     3181 gtacagccgg ttcctgttca agcggatgaa acacctgttc agttcggcgc aagaatcaat
     3241 acagcggcat ttatcacaga aattgctact tatgctcaac caatcgctca agccaacgat
     3301 ctatatgcat cagtgatgat cgcacaagca gttgtagaaa gcggttgggg cagtagtgcg
     3361 ttatctcaag caccttatta taatcttttt gggataaaag gcagctatca aggacaaacc
     3421 gtctacatgg atacgcttga atttttaaat aatcaatggg taaataaaaa ggagcctttc
     3481 cgacaatatc cttcttttgc tgaatctttc aatgacaatg cctatgtact tagaaatact
     3541 tcatttggca acggttatta ctatgccggt acttggaaga gcaacacgaa atcctataca
     3601 gatgcgacag cttgtttgac agggcgttat gcgactgatc ctggttacgc aggcaaatta
     3661 aataatatca tcgcaactta cggattgacc caatatgata caccagctag cggaaacgca
     3721 ggcggtggag cgactacagg tggcaataat actggaagtg caggtagtac tggcggttca
     3781 agcaattctg gtaatacaaa ctcaggttca gcaacttcga ccacttatac tgtccaatct
     3841 ggtgattctg tttggggaat ctcaaataaa ttcggtatca caatggatca attgatccaa
     3901 tggaacaaca tccaaaacaa tttcatttat ccaggacaaa aactgacaat caaaggtagc
     3961 caggaaaatg gctcttcgac gaataattcc ggtaacaata ccaattcttc aggaaatgct
     4021 ggtacatcaa acggaggaca aacaactggt gcgaaataca ctgttcaatc tggtgattct
     4081 gtttggaaga tctcaaatga tcacggaatt acgatggctc aattgattga atggaacaat
     4141 atcaagaaca atttcgttta tccaggacaa cagctaatcg tatcaaatgg cggttcttct
     4201 aatgctggag caaatactgg ctcaaatact gggaatacaa gtggctctag ttcgtccagc
     4261 tcaagttctt ctaatacagc ttcaggaacg aaatatacag ttaaagccgg agactctgtt
     4321 tggagcgtct caaataaata cggaattacg atggctcagc taatccaatg gaacaatatc
     4381 caaaataact ttatctaccc aggacaacaa ctgactgttt caaacagtgg atcaacaaac
     4441 agcacgtcag gtaatacagg ttcgtcaacc aatacaaata acagcagttc agttaatact
     4501 ggcagcagtt cgtctcaagg cacttatacc gtgaaagcag gtgaatctgt ttggagcgtg
     4561 gcaaataaaa acggcatcac gatggatcag ttaatcgaat ggaataatat caaaaacaac
     4621 ttcatttatc caggacagca attgatcgtt aaaggtggaa cttcggcaaa tacaaataca
     4681 ggttcaacta cttctgcagc gaaaccaaat acaccgaata cgtctgctac gacaagtaca
     4741 tcatccactg gtaatacgat gtataccgtg aaagcgggcg agtcagtttg gagcgtagcg
     4801 aacaaacatc atatcacgat ggatcagtta atcgaatgga ataatatcaa aaataatttc
     4861 atctatccag gacagcaagt gattgtgaag aaaggttcat ctcaatcaac aaaccaacaa
     4921 tcagttactg gttcgaaaac ctatactgtg aaatctggag aatctgtttg gagtgttgct
     4981 gacagtcatg gaattacaat ggctcaacta atcgaatgga acaatattaa gaacaacttt
     5041 atttatccag gtcaaacgtt gattgtagct aaataaaata gctgttcgaa gaaataacga
     5101 ttgaattcca caaaaatatt tgttactata aggctactta aatatgacaa cacttgaaaa
     5161 ggaagtagta aaaagactga agtttcagag agcgcatggc tggtgagaat gtgcacggat
     5221 gcttttgaac tcgcctttga gttgcccttg ctgaataccc gagtaagcaa gcggcggtga
     5281 cggccgttac aacgttcgag gccttttcac taaggtaaaa ttaggtggta ccgcgtagat
     5341 tacgtcctat aaaaagagca atctttttat aggatttttt tatttctttt gtgaagtttg
     5401 agaaaacaaa gcaaaaggaa ataaaaataa acagattctg ccggtttttt cgttatattt
     5461 ataatagaaa caagtgtttt caatagaaca ggaggacagc aaatgagtta caatcataaa
     5521 gaaattgaga aaaaatggca aaaatactgg gcaaaaacga atactttcaa cacccatgat
     5581 gatcctgaaa agccaaaatt ttacgcactg gatatgtttc cctatccatc cggtcaaggg
     5641 ctacatgtag ggcatcctga aggttatacg gcaacggata tcctttcacg tgtgaaaaga
     5701 agtcaaggat acaacgtgct gcatccaatg gggtgggatg cattcggtct gcctgctgaa
     5761 caatatgcgc tagatacagg aaacgatcca gctgagttta cccaaaaaaa tatcgaaaca
     5821 ttccgacgcc aaatcaattc tttaggattt agttatgact ggaatcgcga agtgaataca
     5881 actgatccgg agtattataa atggacacaa tggatcttta cgaagcttta tgaaaaaggt
     5941 ctagcttatg aagcagaagt agcggtaaac tgggtacctg aattaggaac agttatttca
     6001 aatgaagaag tgatcgatgg gaaaagtgaa cgtggtggct atgatgtagt cagaaaacca
     6061 atgcgccaat ggatgctgaa aatcactgct tatgctgatc gcttattgga tgatctagaa
     6121 ttagttgatt ggccagaaag cattaaagaa atgcaaagaa attggatcgg tcgttcagta
     6181 ggagcaaata ttgaatttaa agtggctggt acggataaat cctataccgt atttacgaca
     6241 cgaccagata ctctattcgg tgcaacttac tcggttcttg cacctgaact agatcttgtt
     6301 agagaaatta cgacccctga acaaaaagct gctgtagaag cttatatcga agagacagct
     6361 aaaaaatcag atctaaagag aacggatctt gcaaaagaaa aaacaggagt atttactggt
     6421 gcttatgcaa tcaatccagt taatggcaag gaaatcccaa tctggatcgc cgattatgta
     6481 ttatcttcat acggcacagg agccatcatg gctgttccag cacatgatga acgtgacttt
     6541 gaattcgctc aaactttcgg actagaaatt cttccagtta tcgaaggtgg agatgttgaa
     6601 aaagctgctt acacagaaga tggtacgcac atcaactctg aatttctaga cggcatgaac
     6661 aaacaagaag caatcgataa aatgaatgaa tggctagaag aaaatggcgt agggaaaaaa
     6721 gaagtcagct atcgcttacg tgactggcta ttctcccgtc aacgttactg gggtgaacca
     6781 atcccaatca tccattggga ggacggaaca gtcacagctg tcccagaaga agagctacca
     6841 ttacggttgc ctaagacaaa aaacatcaag ccaagcggta ctggagaatc tccattagca
     6901 aatatcgagg agtgggtcaa tgtcgttgat cctgtaacag gtaaaaaagg ccgtcgcgaa
     6961 acgaatacaa tgccacaatg ggcaggaagc tcatggtatt acctgcgtta tatcgaccct
     7021 cataacaaaa aagaactagc agattatgaa aagttgaagc gttggctacc agttgacatc
     7081 tacattggtg gagcagaaca tgcggtactt catttactat atgcacgatt ctggcataaa
     7141 ttcttatacg atatcggtgt tgttcctaca aaagaaccat tccaaaaact atacaatcaa
     7201 ggaatgatct taggcgaaaa caacgaaaaa atgtcaaaat ctcgtggtaa tgtagtcaat
     7261 cctgatgatg tggtcgaaac ttacggtgca gatacactgc gcatgtacga aatgttcatg
     7321 gggccattag atgcttcgat tgcttggagc gaaaatggct tagaaggaag ccgtaaattc
     7381 ttggatcgtg tatggcgttt gatcgttgat gagaacaata aaatgcgtga ccgtatcact
     7441 acattgaatg atggcaagct tgataaagtg tatcatcaaa cagtgaaaaa agtgacagaa
     7501 gactatgaaa atcttcattt caatacagca atctcccaat tgatggtctt tatcaatgaa
     7561 gcctataaag tggacgctct gccttatgaa tatatcgaag gatttgttca actactcgca
     7621 ccgattgctc ctcacatggg tgaagaacta tgggcaatcc ttggaaatga tggtggtatt
     7681 tcttacgcac catggccaac atacgatgaa gcagcacttg ttgaagacga agtagaagtt
     7741 gttttccaag taaacggtaa agttcgtgcg aaaagcaatg ttccccgaga cttaggaaaa
     7801 gatgagctag aaaaagcagc attagccaat gaaatagtgc aagaatatat tgaaggcaaa
     7861 acagtcagaa aagttattgc ggtaccaaac aagttagtca atatcgttgc taattaattg
     7921 gctctttgtc aataaggact gatgagttgt gcaaaatcaa atctgggcca gaatgaactt
     7981 cattctgtct cagatttttt gttatttcaa attgattaat tgattgatca aaaaggtttt
     8041 gattttcatg ttctcaaaca cgttcaatgt ctttttcttc tgaatggtct tgtaagagat
     8101 ctctgtaatc atcaaatttt tgtctattaa tcttagtatt ttttgatgta taaactacct
     8161 gaaattgaga gtacatacca aattcataaa ttttttatta gtgggactag tgattgtatg
     8221 gattttgacg cataatgaat gaagtatgag aaaaggagag acaaatggat caagaactat
     8281 ttattatcga agtattatca gctaaacaaa aaattatcga gaaagcgaaa aaaagagcga
     8341 aaagaataat gttcaagctt ttaagcttag tatttttctc tggtttgctt tttttcggag
     8401 ctgtatcgtt cctatatcgc catatgagtg cagtagtccg ttcagctgaa gggatgcaaa
     8461 aattaaataa tttgtatcac ttttcgtggg gagttggcgg aataacaatt gttgtgctta
     8521 ttgtttttct tctacttatt tggctccgtt accatcaatt gtcgcgtcat ttcgatcaat
     8581 ggcttagtca aagagcacaa cagtttttac ataataaacc aacttctcaa gatgatgact
     8641 atctttattt tgagaagact tcgacgagtc aagcttttcg gatacaaaaa agtgattgcc
     8701 agttattgct gagatcactt gatgatttac ctatctactt aggcgaaagc aaatcaaaat
     8761 tcggaatgaa cacattccat atttttttac tagaaaacga acccagatgg gaaaaaagcc
     8821 agtcttcgcc tggtggatac ctgacaacta agatgagtac attagtcact ggttttttcc
     8881 tcattctttt agctggaaca atctattatg ggagatacac tcagccaaaa atgtcttctc
     8941 atataaatgc tgcttctcac atgacaatga actcaactaa cgatacgcat atacaaaaga
     9001 caaatgaagg gttgttagct gatcctaagc aaaaggtaaa tttgacaaca caaaagataa
     9061 atgatctcaa acttgataca gagacgcact ctctctatat gacaacagat agtggtgcta
     9121 attgggtatt tgtgccgatt gattcgcaat ggttgcgttt tggcgaatac accctgacaa
     9181 cggggctgat tcctgaaggt tattggatgg acaacacata tgatatttcc gccgatttct
     9241 catggtttat ctattcttct ggggatgatg tacgtctgct gacttcaaga gataatggta
     9301 aaacatggca aacgtctatt atcacccaat cagttcagcc gatacgttat cgaaaagcgg
     9361 tattttatgg caacgatggt ctatttatct gtacatcagc cagtgggatg tctgcagaaa
     9421 ctttgtacat ttacactact atggatggcg gaatcacttg gataaaaagt ggaagtacaa
     9481 tgatcaatca gccagtacaa aatgtcagct tcgttacaac ttctttaggt tttgtttcga
     9541 cacgtgaaag tttgttttat acaaacaacg gaggacgctc attcaaagaa tcagttctgt
     9601 cgattccgga aaactatcag acagggggga tagatctttt tcaatcacca aatgaagtta
     9661 ctcaaataag cgcgaatacg ttagagacaa aattttattt gttgaaaaaa ggaccaatcg
     9721 atgcagggaa aatgtttgcc tgcctcttcc gttcaactga taacggggaa acatggcaat
     9781 tcgttcagca actatcgcaa gtagaacaag gagattaaag aagagagatt gtgagcctga
     9841 cgttcagcac cgagtcacaa gaaacaaatt caaaaaacag cttctcatat ttgttgaata
     9901 gtgtaactcg tgattcggag ttgacaagag caacaagaag cgattttgaa gtatagcttc
     9961 tcgtatttta caagatcgtg tcttattgcc gataggttgt ctcttgaaca ccgtttattc
    10021 gtaaaaaggg attgtgacaa gtcttttgtc actacttacc gaacgaaact gaaggagcta
    10081 tccaaaaagt atcattagta ttattctttg tgtttctagt ggcaccacta gtacatttaa
    10141 aaaagctatc gatcatggac taatcataca tgatcgatag ctttttagat aatgtttgtt
    10201 acgctatctg aaattgacta ttataaagac tggcataaag cgttggtgat tggagtagtt
    10261 cagaatgtgt tcctttttcg acgatatcgc cattcttcat tacaaggatc atgtctgcat
    10321 tttcaatcgt tgacaaacgg tgtgcaatca caaaacttgt cctatctttt gtcacagctt
    10381 ccattgcttg ctgaatcaat gcttctgttc gtgtatctac gctagaagtt gcttcatcta
    10441 aaataacgac aggaggattc gctagaatga ctcgagcaat tgtcaataat tgttgctgtc
    10501 cttgagataa cgtgccgttt tcgctagaaa tgatcgtatc atatccgtct ggcagtgttc
    10561 gaataaagtg atcacattgt gcgatttcag ccgcttcgat aatttgttct cttgtggcat
    10621 ccattttccc gtaggcgata ttatcagcta ccgttccttc aaacagccag gtattttgta
    10681 aaaccatccc aaaagaacga cgtagttctc cacgtgaaag cttggtaata tcaagaccgt
    10741 cgaattcgat ctttccttta ttcagttcat aaaaacgcat cagcagattg actaaagtcg
    10801 tttttcctgc accagttgga ccaacgatcg ctaccgtttg ttttggcttt actgaaaaat
    10861 cgacttgatt catcaatatt ttatctgatg tgtaaccaaa ctgtacattt ttgaaagcta
    10921 tttttccttt cggttgttct aaaagtcttg catctggaag gtctggaatt tcatctgttt
    10981 catctaatat ctcaaatatc ctatcgattg ctgccattgc ggattggatc gagttgatca
    11041 cataagaagc ggtagaaatt ggttcagaaa tctgattgat gtactgaaga taagcttgta
    11101 agaagccgat cgtcacacca cctgatagaa caagcatagc accgaatacc gcacttatga
    11161 tgaaggcgag ttgattaatg aaacgaatgg ccggatagat agcacagttc ataaattgag
    11221 cacgtttaaa agcgttgtat tgctttttat ttacttcgtg tatagcagct tctgcatgag
    11281 cttgctgatt gaatgttttg accactagat taccagctaa gatttcttcc attcgattat
    11341 ttaaaacacc cagttcatac tgattctgtt cagaaatctg tttgtttttg ttcgcaatct
    11401 tagttgtaac aattgaactg ccaacgatca gcaataagac gagcaaagta agcttgcttt
    11461 cgatataaaa cagcatcaga ccagcagcag ctattgttac gacagaagta aaaaattgat
    11521 tgatacctgt caataacact tgagaaagtt gattgagacc ggtagttgtc cgactaatga
    11581 tgtcacctac ttgatgattg tcaaaaaacg acatcggtaa tgttttgaat ttttttgtga
    11641 tttcttttcg caccctcaat gtgatctttt cgcttaacgc tgccattgtc cgttcctgaa
    11701 taaatgaagt gatgctgctt aagactgaac agccgatcag caataagaca gggaacaaca
    11761 atgcttgttt gatatcactg aaagaaagct gtccaatacc tgtttttctt atttctgata
    11821 agagatcatc gatcccgatt cccatgatca agggcatggc tacgactaat aggttcccga
    11881 ataaactgca tagaaacaat ccgtaaaaat atttatgttc aggtttgatc attttccaaa
    11941 aacgtatcaa agcacgcgtg ttcaacgttt ttttcttttc catcgtatcc cttctttcta
    12001 tattccttgt gattttgcaa actcctgata agtttggcaa ttagacagta gttcttcatg
    12061 agtaccttgt ccaacgattt ttccttcatc taaaacaatg atgttatctg cttgttggat
    12121 tgtactgagg cgttgagcaa caatcacgag agttttctcc gacatgtgtt tatgaagggc
    12181 tgctcttaat gctgcatctg ttttatagtc taaagcggag aaactatcat cgaatacata
    12241 gatctctgct ggtttgatca acgctcgagc aatacatatc cgctgtttct ggccccctga
    12301 ataattagaa ccgccttgag caacaaagct gtccaatccg tcaggaaggg tgtccactag
    12361 ttcttctaat tgagcgatct tgatcgcttt agacaactct tctgttgagg catattcatt
    12421 tcccatctgc aagttgctta aaattgtccc gctgaataag aaagccttct gagggacata
    12481 actgatgtgg gagcggatct gttcttgagt catttgagta agaggaatac caccaagggt
    12541 tacttttcct atcgtagggt cactaagtct caagagaagt ttcgccaaac tactttttcc
    12601 agatccggtc ccgccaacga tcgctgttgt ttttccttta ggtattgtga aatcaatatc
    12661 ttctagaact ggatcagaga tttcagtata tttaaatgtg acatgttcaa aagcagctgc
    12721 atttgtctga tcaaaggttg gttcagctac tgttttgatc gtctcttcct caatttcgat
    12781 ctctgcttgc agtatttctt ctatccgtcg taatgaggca aacgatttag ggataatgac
    12841 caataccata gctgcgatca tcaagtaagc aagtgtcagc atagagtatt cgactacagc
    12901 agtcacgaca ccgatttgta atgctccttc tgctacaaga tttccgccaa accacaaaat
    12961 agaagcataa acgattccca tgagcaaaaa agcaattgga gtgacccaag caaatattcg
    13021 gttcactttg atcatttgat tagcatagtc agcaaagctc ttattcgttc gcttttcttc
    13081 atatgattga ttatcaaagg cacggatcat attaatccca gtaaagaatt ctctcaatgt
    13141 gatggtgatc cgatccattt ttggctggat actcaaagat aaaggtgccc ctcgtttcat
    13201 cagtcgataa acaatccata cataaaaaac aacagagatc aatgtaaccc atgttagtaa
    13261 tagagaataa cgaaacatca tgagaatggt gaaaacgcaa ataaccggtg ctggtaagat
    13321 catttggcaa aataaaacaa tcatttgctg gacattatcg acatcattcg tcattcttgt
    13381 caaaagagat ccagaactaa aacgactgat atccttcatt gacagctgtt ggaatttacg
    13441 gaaatatttc tcccgcgttt ggaatccaaa cctagcggaa gccaatgctg aaaagtaact
    13501 agaggcaact gcagcgattg ttcctagaaa cgctacaagc agcatttcaa ctccaatttt
    13561 ttttataact gaggcttcgc cacttgctat acctgtgtcg atcagctttg ctactaattt
    13621 tggtacacct aatgtaccgg cgatttctaa acagatcatc acaaaggtaa ggagagcgag
    13681 tcctttgttt ttctgtaaga atgtttttaa gatagacata ttattcctcc ttttttcctg
    13741 atacttttcg attctatacc ttcaagtaac ttgaaggtca atagaaaaaa gaataaactg
    13801 aaaaagaggt gagaaaaaat gaaaaaaatg tatacgattg gccaagtatc ggaactattt
    13861 gatttgccaa aatcaacgat ccgctattgg gatgaacaag gattaatccg ttcaagtaga
    13921 caagaagaga atgattatcg attgtttgat atcgatgata tttttatgct ttatgatatc
    13981 gttttttata gaaaattaga tataccgatc aaacagatga agaatttata tggaaaaaca
    14041 ttgacggagt tatatgagac acttgatgaa acagaaagaa gaatccataa agaactggtg
    14101 gtgatgaaac aaaaacaaaa agagataagg gagcaaaaaa aacagttgaa attgatgatc
    14161 gatacaaacg aggaagaatt tcctgtagaa gagatccctt ttgactgtat gatctcaacg
    14221 gagtttgaag atattgtgga aatcaaaaaa tttctaccta actattcaag ctttgggatg
    14281 atgagtatgc cagcttccag ttcacagacg atgtatggat tttttatcga ccctagtgaa
    14341 gtacatttat ttactcaaga cgtgatttgg gagaaaaaag atacggctgt ttatcgtcga
    14401 ttcttattga aatccgagat gaaccatgcg gaacgtaata atattttaga aatcagagaa
    14461 agaatgtatg aaaaaggatg gaaaacagga gaagtgatcg gccagtatct attgacgaat
    14521 acggatgaaa acaatatcag aactgaatat tatcatgcat ggatagaaat gaaaaaatag
    14581 gaaatatgtg tttaagataa ctcgaaaatg atggttgttt tagttataaa gaaaaatttt
    14641 ctggttcgat tacgggttta atgtggggga ttattagtcg tggatagata gaattttagt
    14701 tttttagagg aaatatgtct ttaaaaatgg aatggttgca attcttagcg atatatacga
    14761 tgtaattgtc ctcttaaaaa agtatggaaa aataattgta ttgggtgtta tgtataattc
    14821 atggtgaact gagactaatg agaagaaaaa ttcatattgt tatgagtgag attgtatcag
    14881 atgagaatga taaattaaat aggtgcataa aagcattaca cttaaaatac attgttgctt
    14941 acattattac aatatgttaa taaggcaaaa ataaatagat ggattgaata aacatatttt
    15001 ttaatcaaat agtccctact gtgactttcc tcagctatcg gtgatactac cgatagcatt
    15061 tttttgctta taaaataatt ataagtattt agagattttt cttctaacat tcttcaaaca
    15121 agaaaaatca caaaggttat tgttattttt atatattctt tttaagaatg attgtttttt
    15181 tatagaaatt ttaaaaaata aaacacgtta ttgatggata gttagtttgt tatttggtaa
    15241 tattatagaa gttgactggt agtgatttat ttttcgtcgt tttataaaaa tgttattttt
    15301 tggaaaaatt cacaaatatg taacgaatgt ttttctggaa tttgctgtgt taaaaagcag
    15361 tatgactaat ataaatacta ttgtcattta tgcaattttt tatggatagt aattttagag
    15421 gggaatcaat gaaggaagaa tagaagggaa aaatagttgc aaatacgcca gttagcaaaa
    15481 atagcaatac atcttcaagc tttaaaattc gagagaatca tcttggtagt ggaatcaact
    15541 acaacaaaag gattaaacca attaatagat agaattacca atggaaaaat agaaaaggta
    15601 gttattctat acaaaagttg tttaattcgc ttcggttatg aacttagtga aaccctttgc
    15661 aatatatggt acagaatata gaaattattg acattacaga aaatgatgaa gatttaatac
    15721 agattgtcac tatttgtaga taccttttac aaggaaaccg agccaataaa gctaagaaga
    15781 tgattaagga gttgatggaa gacgatacaa gttaagaaag tgaaactacg cccaaataaa
    15841 gagcaaaaag agtaattgga cgtggaaaat gcaagaaatg aaccatcgat tcggtggaca
    15901 gtttattagt aatgacggtt tgagaacatc catgacgaga atgaaggaac atcctaaatg
    15961 cgtttagttg aaccaagtgc caaataatat ggccaaataa gcgatcagtt atcgatgaat
    16021 cccaagtatt ctaaactata tattcatttt gatgctaagc attgatatat ttttttggga
    16081 ttgatgaagg ttaaccaata cagggactca ctgatgaaat tctagagtct gaccttggta
    16141 tcaacgattt agtgattgtt tctaatggaa aagtataaaa gtatataagt acattaacaa
    16201 aataactatt agggttacgc tccagcttgt gcaaggcact ggcaggagga atcgtgaaat
    16261 cataattatg gttaagccac acggacaact aaaagtcata caaagctatc gaatcaatca
    16321 acagaagaca atcggcaatc attagctttg tttacagctt acattgcaac gcttgagttg
    16381 aaccgaaaat acgagggagg taacgcagcc attttgagtt ggggaatctt tttagaaaat
    16441 tatcgggtac cttgttgttt agtcaaaatt ataaggggga gtaatagtga ggaacaaatt
    16501 tcataaactg ttaagtatgt ttctagttat gcttattgtg atcaatcaat ttgggaacat
    16561 aacggttcta gctgagtctt tagcagaaca gccagagcgt tcgctgacga tcgaagttga
    16621 tcaagaggag gctgctttgg gtgagcagtt ccagttgcga gtcagaggaa caccagacct
    16681 gctaaatgca ttggtcattg ataagagtga ggatttgatt gaaggggaag tgaagcaact
    16741 caatgattac gaacgtctga ttacttattc ttcccagcat tcaggtaaat acgaattgac
    16801 cgcaagaagc ggtgatattc aatcaaatac ggtctcaata gaaatcagtg taccagaaga
    16861 aagcacaagt gagtctttta atgtaccaga agaaagcaca agtgaatctt ttaatatacc
    16921 agaagaaagc ttaagtgaat cttttaatga agccagatca tctgagccat ctataacgca
    16981 ggaatctcag attgaaagac aagaggagct cttgaattat gacatcggca tctctgctga
    17041 gcgccccact ttgccgagca ggcatacaca aacgttaaag ggatacattc aaggaggcgc
    17101 tggcgatatt cttgaagaat atggggagat ggtcgtacga gttcctagag catcgattgg
    17161 cttaattgag ttcattagag tggaggtcgc tgatgattca cctttaaagc cactggcatt
    17221 ttaccaagaa ggcacagacg ttgtttttcc atttaccttt gattatgaag gattaaatga
    17281 agccgctcag tcgtatacat tcagtatcac gtttgaagtt gctttctttc aatcaggcgg
    17341 tactgagcca aataatgact ttcaagtgag tcttacttat gctgagcgag cagcaaacac
    17401 ggaattttca attacgccta ttccttcatc aagacccatt ttttcgaaat tatactatgg
    17461 ctctagagaa atcgacagcc aaggaaatct tgggaatctg ctgattgacg ggcaagacgt
    17521 gaccaacagt aataaattta ttttgcaggt aaattatgaa ggatcacgaa aagacggtgt
    17581 agtggttacc gatgtactac cgcaaggaac aactttggca ccgaatccga ctacatggag
    17641 ttccactgga aatagagaac ctatttcagg tggggttcgg atcgcagaag taacgaatcc
    17701 aggtgaagca aacgttagaa ctcattatgt ttccgaggaa tttgtggaca aagtatcttt
    17761 taataaggaa acgaatacac ttgttgtgga ctttggtaat ctagcagagg gtcaatcgta
    17821 ttttattgaa tatgctcttg aagtgaccga tgtcgacttg ttcaatgaag gaagacaaga
    17881 ggatgggttt tctcggaatc gagcgagtat gacctacaat aatcaggtaa tgagccgaga
    17941 ctaccgcttg agaatccctg aaagtaatct tccggcaatc tctttaagaa aaagtgtgga
    18001 caaaaatgtt atcaatctca atgaaaatga actaacgtat actctgcatg tctcgatgtt
    18061 ttctggaaca agaaatacgc ttgttattga agatgttttg gaagaaggca tggaatttgt
    18121 gtcatttcta tcagatattc cctctttcat tgatgccgaa gtcaataatg gaatagttcg
    18181 tttcagtgcg aataatacga ttggtggtcc gacaagtttt accctctctt ttaaggtcaa
    18241 tgtagaggcg tatgcggtcg gcgatcaaat tttaaacttt gcaacgcttg tgaatagtga
    18301 caatcgattg aatacgagta ctgtaagaac aaggaaaatc gatgggcgta ttaaagtaat
    18361 taaaactgat gagaatggcc aaaggctggc aggagcaaaa tttgaaattt tatcaagcga
    18421 ttcacaagtg atacaagaag gtataacggc agaaaacgga gaatttttaa gtgaaccgct
    18481 tcctgtaggt agctatcaag tccgagaaac agaagcaccg gaagggtatc ttttagatgc
    18541 gacggtacat gatgttttta taaatgaata ctccatagaa gaagtgacgt taaccattga
    18601 aaacatcctt gatacgggtg gtgttgaact aattaaacat gctgaaggca gtggtgaagt
    18661 ccttcaagga gctgtttttg agttacagaa ccgagaagga gaaacgctac aaaccggttt
    18721 aactacagga gaagatggaa aactggcaat tgacggttta gcaccaggag catatcagct
    18781 ggtagaaac
//
LOCUS       DBBGSZ010000046        18713 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.048, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000046 DBBGSZ010000000
VERSION     DBBGSZ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18713
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.048"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            105..404
                     /locus_tag="ACIZE5_002279"
     CDS             105..404
                     /locus_tag="ACIZE5_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109392.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(501..935)
                     /locus_tag="ACIZE5_002280"
     CDS             complement(501..935)
                     /locus_tag="ACIZE5_002280"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6109393.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1167..1877)
                     /locus_tag="ACIZE5_002281"
     CDS             complement(1167..1877)
                     /locus_tag="ACIZE5_002281"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HGC6109394.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(1867..2727)
                     /locus_tag="ACIZE5_002282"
     CDS             complement(1867..2727)
                     /locus_tag="ACIZE5_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HGC6109395.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(2732..3370)
                     /locus_tag="ACIZE5_002283"
     CDS             complement(2732..3370)
                     /locus_tag="ACIZE5_002283"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HGC6109396.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3385..3684)
                     /locus_tag="ACIZE5_002284"
     CDS             complement(3385..3684)
                     /locus_tag="ACIZE5_002284"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC6109397.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(3727..5211)
                     /locus_tag="ACIZE5_002285"
     CDS             complement(3727..5211)
                     /locus_tag="ACIZE5_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGC6109398.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5231..5692)
                     /locus_tag="ACIZE5_002286"
     CDS             complement(5231..5692)
                     /locus_tag="ACIZE5_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC6109399.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(5710..6777)
                     /gene="ulaG"
                     /locus_tag="ACIZE5_002287"
     CDS             complement(5710..6777)
                     /gene="ulaG"
                     /locus_tag="ACIZE5_002287"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HGC6109400.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            6995..7765
                     /locus_tag="ACIZE5_002288"
     CDS             6995..7765
                     /locus_tag="ACIZE5_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGC6109401.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8038..8865)
                     /locus_tag="ACIZE5_002289"
     CDS             complement(8038..8865)
                     /locus_tag="ACIZE5_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6109402.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9433..10668
                     /locus_tag="ACIZE5_002290"
     CDS             9433..10668
                     /locus_tag="ACIZE5_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGC6109403.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(11667..11927)
                     /locus_tag="ACIZE5_002291"
     CDS             complement(11667..11927)
                     /locus_tag="ACIZE5_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HGC6109404.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(11954..13255)
                     /locus_tag="ACIZE5_002292"
     CDS             complement(11954..13255)
                     /locus_tag="ACIZE5_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC6109405.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(13547..14005)
                     /locus_tag="ACIZE5_002293"
     CDS             complement(13547..14005)
                     /locus_tag="ACIZE5_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HGC6109406.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14018..15349)
                     /locus_tag="ACIZE5_002294"
     CDS             complement(14018..15349)
                     /locus_tag="ACIZE5_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HGC6109407.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15360..16802)
                     /locus_tag="ACIZE5_002295"
     CDS             complement(15360..16802)
                     /locus_tag="ACIZE5_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC6109408.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(16789..17553)
                     /locus_tag="ACIZE5_002296"
     CDS             complement(16789..17553)
                     /locus_tag="ACIZE5_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HGC6109409.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(17657..18532)
                     /locus_tag="ACIZE5_002297"
     CDS             complement(17657..18532)
                     /locus_tag="ACIZE5_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGC6109410.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
BASE COUNT         5896 a         3887 c         2866 g         6064 t
ORIGIN      
        1 gctatatcaa gatgaatcaa atatacttgt cattcatcat gaaatataga gacttataaa
       61 attgtttatt tttataatgt atcagtatag aaaggaaata aaacatggat tatactgttg
      121 aatttgacag tgaactactt aagcaatttc cacaagaaga acatttcatg tataaagaag
      181 caatttccca caaagtgaca gagtatttgg agcataattt ttttcgtata aagccagtgc
      241 gtactcgttc ggcaaaagga atatacgaga tgaaagtcaa aattaataaa aaaaattatc
      301 gcatagcatt tgctttaaaa aaaaatcatg tgttcatttt ttatattagt tcgaatttgc
      361 aaaaaattgt atttgataaa gaggtgagta aaaaaataaa atagctgagc attggaggat
      421 agattgagtg atactaagtc tatcctcttg tttttctaaa gaactaagct agaatttttt
      481 cttttgtacg ttattatatg ttatttgtca ttaccaaaaa gcaccttttt tcttctagta
      541 tctatgacat aagaaatacc acccatttcc tttacttgaa caaatcctac tgattcataa
      601 aatttttttg ttttctcagt atcatctgtc aataattcga tttggactgg tccataacta
      661 gtgatcttct ccaaagcttc attcaaaagc actttgccta ttccttggcg ctgatacctc
      721 ggatgaatga ggatatcttg aataaatgcg atcgtcgcaa aatcagtgat ccaacgaacg
      781 attccgataa tcttcccttc cccattacgc tttatcagag attcagattg ttcaaatgct
      841 ctagctaacc ttgcagtgtc ttttgtgtaa ttcgtccaac caacgctctt atataattca
      901 gaaatctcat cgatcataag ggaatcaata ttcatttttt tcttcctttc ttatacaatt
      961 ctccctctaa taatacagtt ctttgactat ttaatctatc acatataact ctcctgtaaa
     1021 gattctctcg attccttaaa attcctcttt ccttttagaa tgcatacttt ttgataaata
     1081 aaaaggttgt gataaatttt cttcacaacc tctgtttctc tctatcaagt gttatctttt
     1141 aattttctac ccttacccta gcatctctat tgcccgtagt atgcatactt tccatgtttg
     1201 cgaaaataat gtttatctag taaatattgc gggatttcac atatattggg gttgatcagc
     1261 tcgttttctt tggccatcag acaaatttca tctaagatca aactgttttc tactgctttc
     1321 ataggtgaat ccccccatgt gaacggtcca tgtccataga caagtactcc agggacttcg
     1381 tttggatcta attttctttc cttaaacgtc tcgacaatca cattccctgt atgaacttcg
     1441 taagcttctc ttacttcttc tttcgttaat tggcgtgtac aaggaacctt accataaaaa
     1501 gcatcagcat gagtcgtgcc ataagctggc aaatcgcgtc ctgcttgcgc ccacatgacg
     1561 gagtgcgtgg aatgagtatg agtaatagca gttatatctt caaaagtttg atacaaaaca
     1621 acatgtgtgg ggagatctga agatggtttt aagctatctt cttctattat atttcccgac
     1681 aaatctgtta ccaccatttg atctgcttgc atgcattcat atctgacacc gcttggctta
     1741 atgacgatga ctcctagctc acggtccact tcactcacat tgccccaagt caatttgact
     1801 aatccgtatc gcggcaatgc cagatttgct tcaaggacac gttgcttcat tgctgcaatt
     1861 ttttcttcac aagacatcat agccagcctc cttcaattta gaacttaagt agtcttttgc
     1921 ctgctggatt tctcttcgaa agtcttggct tttttcactc cacatttcaa tcagaaatgt
     1981 tccatcataa tctagacgtt tcaaatgtct taataatcca agaaaatcaa cacaaccgct
     2041 accaaaagga acatcacgaa actggcctga atattctttt gttacagggt aagtatcttt
     2101 taagtggata gcagtgatat aatcgatccc tttctcaagt tctcgagccg gattattttc
     2161 cggccatgcg gacaaattgc ctaggtctgg atatacttgt agaaaaggtg aatgaatctg
     2221 ttctttgatt tctaaaaatt ttgaaatgga gttcataaat ggatcatcca tgatttccac
     2281 ggaaagaatg atgccatatt tagaagcttc ctttacgctt tcttttattc cttcgataaa
     2341 gtcttctctg gaattcattg atttctcttc ataataaaca tcgtatccag ctatttggat
     2401 tactttgacg cttagattat gcgccaaatg gattgctttt ttcattagtt gtttcgctgc
     2461 ttttttcttt tctggatcag cagaaccaaa cggaaatcgc cgatgcgcac ttaaacaaat
     2521 cgaatggata cgtacaccgg agctgaacat ctcttctctc agctcagcta tcttttcttc
     2581 agaccaatct aatcgtgcta accgctcatc cgtctcatca atcgacatct cgataaaatc
     2641 gaagtccatt tcttttacaa gggaaaaacg ttctttccat gaaatatctt tgggtaacgc
     2701 tttttcataa atcccaattt gagccatttc cttaccccca gatacgaatg atctcatctt
     2761 tgaagttttg tgcggccttc atcggatcat ttgctgctgt aataccacga ccagtgataa
     2821 aggtatacac atcgatccct tcaaataagt gtaatgtgtg tggatttaat ccaccagtta
     2881 cagaaacatt aaagcctagt tcaatcagtt ttttgatctt cgataaatct ttttcacccc
     2941 aagtttcacc agataacagc gcatcacggc tttgatggta gattacctgc cggataccga
     3001 tgttatgcca atccatggct tgttcaaaag tccaattgcc gtagagttct acttgcaatt
     3061 cacctatttc tttttgtgct gcctccatag ttggaatcgt tgcacaacaa atgactgtca
     3121 tccagtctgc tcctgctttt gcaacattac tcgccactgt tcctccagcg tctgcacatt
     3181 tcgtatcagc gactagtttt ttatctggga acatactgcg aatacagcga atcgcttttt
     3241 gtccttcctg taagcaaaga attgtgccca cttcaataat atctactaca tcaccaactt
     3301 tcataacatc tcctaatgca tgttctaagt cattgtgatc taacgcaatt tgcaaattcg
     3361 gcctgctcat cttagttcct tcctttactt gtttttttgg taccactttg tttcagcaaa
     3421 tttttcactg atttctttga ctgacatcac atttttgata ccgataactg taactccttt
     3481 tttctctgcc tgagtaaaca tattcaaaaa attgactggc gtaaaaacta catcgtattg
     3541 gccagctgaa ctttttccct ctgaaatggc acaatgatgg attttggtaa ttggtacgtt
     3601 tagttctttc attgcttttt ccacacttct catcatcatc aagcttgttc ctgatccatt
     3661 tgcacacgat actaaaattc tcatcttaat ccctccatta tgagtgttgt ctaatcagat
     3721 tttcttttat actctctgct tttctgcata tgtgtcatag tcttctacaa tcaaaaaata
     3781 accatcagga tttttccgat attgtaactg cggaatagcc aataaaccaa tgacaactac
     3841 ggcaattcca gcataaccta ggactttcat gattactgta aacaatggcc aagctgttgc
     3901 ccagtcgaac atcccgatat aaccaccgta tgttgacatc ccaatccatg tagcgaataa
     3961 tgctgaaccg cctacttgta tgattcctga aagaaacggg aacaggcaag cggctttgaa
     4021 tccacctcgg ttattggcat aaactgctat aacggcatta tcaaagaaca acggaatgaa
     4081 accggctatg acgatcgttg gtgatttcaa taaaatcagt aaaccaatca tcaaaaactg
     4141 tcccaaagca ccaaacaaga acccaatcgt taccgcattt ggcgaaccaa agccaaaagt
     4201 agcagctacg tcaattcctg gaacagctcc tggtaaaatc gtgtttgaga ttccttggaa
     4261 agattgagtt agttcatcga cgaatgtccg aacacctaat tgcaagatcg ccagatatac
     4321 cgcaaaattt aaagaagtcg tcataatgta gaataagaaa ctctgccctt cttgcatgaa
     4381 ttgcgcttga atcaaataat ctttgcctag tacaatcaga atgatcccaa agaaaaatag
     4441 catgagtaac gaagtagcaa ccatattctc attgaaaatc gacaagaatc ctggtaattt
     4501 gatatcttca atttttttgt cttgcttgat tgatctattt ttcttttcat cccgcttttt
     4561 catccactca gctaattttg caaatataaa gattccgaac atttgctgat gtgccactgc
     4621 aaatccggca ccttctgtca attcctgcgt gattcctact gttaagttag aagctactgt
     4681 ccaataacaa cctaaaatca gtcccataaa aatcaatgct tgtatcctac ctagatcagg
     4741 aaagcaaaac agtaaaatcc aaaaagcggt agctgcttgt tgaacctgaa cgtttccggt
     4801 agtgaaaacg gaacgcagtt tcgtatattt ctgaaaacgg actaataaga tatttaaaac
     4861 aaatgcaatc agtaataaaa tcatcacatc tccaaaggta cggccaaatg tctccattaa
     4921 tccagcatcc acagcatttt gtccaaaata aggatctgta accatggcat ccaaattgaa
     4981 ccgttccttt agtccaacca agattggccg aaaattattg accaaaccac cagagccaac
     5041 agtcaaaata aagtaaccga ccgttgcctt taagaatcca gcgatgcatt catgaagcgg
     5101 gcgtttcagc aaaatatagc ctaataacac gataaaacca atcaggtatg ctggctgcgt
     5161 caagatattt gttgcaaaat acgtccaaat gcttaacaaa aattccccca tcttttttct
     5221 cctctatcaa ttaattatat tctgccatca caacttggta atcatcgatg gagttcgtag
     5281 agatgagacg ctcaaccaat ccatctgtca ttaataattc ggataatttt tggatatttt
     5341 ctagatgttc ttctggatct tttgctgcga gtgtaaaaaa caaactagcc gttttctcct
     5401 cattctcccc ttcactttca aaacggattg gctgtttcaa cttggtaaat gaaatagctg
     5461 ttccaaaaac accatcactt ttttctgaag aatgcggcat tgctacttga ggtgcgatca
     5521 caatataagg accgtatttt tctacacaat ggatgatctc ctccacatac gtttcatcaa
     5581 taatttcctt atcgatcaat acaagacagc tttcggcgat agcttcacgc caatccgtga
     5641 tttctttatc tgggtaatga atcaattgat ggtcaaaaaa gtatttcagc aagaaactcc
     5701 ccttctttct tataaaaacg acggaaacgg tgtatcattt tcaatcgaga agacatcttc
     5761 aaatcctcga taaaaattaa actcaagatc atctttgttt gtcggataga tgaatttccc
     5821 gcctacttgc cagatataag gtttaaatcc atacttcagg cgatcctttt tgaatttcca
     5881 aatttcagtg atctcttttg gatcagccat aaaattagac caaatatcgt agtggacagg
     5941 aatcactact tttgcattca atgactccgc catgcgcagc atatcaacag aagtaacttt
     6001 gtctgttatc cctcgtgggt tttcaccata ggcccctaaa cagacatcga ttttgtgttc
     6061 attaccatgt ttggcaaata aattggagta atgtgaatct cctgcatgat aaagattccc
     6121 tcctgatgtt tcgaataaat agtttactgc aatttgatcc atctcctgag gcatttttcc
     6181 ttttaatacc tcttctggat cttcacaagt gaccaacgct gtccgatcaa acgcttctaa
     6241 agctactaca ttgatgtctt tgattttgac tgcatcacct ggctttactg taatcgtttt
     6301 ttcttcagga attccccatt tttgccacgt gcgaaccact tcttttggcc caatgaatgt
     6361 tgcttcagga caattttgat gaactgctgc ggctgtatgg atatctagat gatcggaatg
     6421 gatatgtgta acgattaaag cgtctacatt ttttatcgca aaaggatcga ttacgaaagg
     6481 ctgagtacgt aaattaggct gcatattttg aacgccactc atacgcatca tctgatggcc
     6541 ttttttcatc atgccattcc catgactacg ttttcccgtc ccacaccata gatcacataa
     6601 aatattcgtt ccttcatgac ttttcagcca aattcccgta cagcccagcc accacatagc
     6661 aaaagttcca ggatccacta cttctgtttc gatttcttca ttcaagtatg tgccccactc
     6721 aggaaatgtt tctactaacc acttttcttt tgttacttca ttgacagttt tactcatttg
     6781 cttgctcccc ccatatcgtt gttccaactt acaagtaaat attaatgtgt atcagcatcc
     6841 atgaaaaccc ttttatatga ccgtttgttt tttatatgat tttctttcag taatcaatga
     6901 ttgtttcagt ataataaaga cagatatgaa tgtttaaatg aacaactagt caaataaatc
     6961 catggatcaa gatgtccctc aggaggcaaa agtcatgaaa aactcacttg tcaatattga
     7021 aaaacgtcaa aaagaaattt tggaactgct tcagcagact gaacaactat caactttcga
     7081 attagctgaa tcccttgatg tatctattag tacgatacga agagatttaa atttattaga
     7141 agaaaaaaac gagatcatac gcaattacgg ttattgttct tataattaca aaaaccagac
     7201 tgattttgat caatctggtc ctgaaaggat taaacaagcg attgccagag aagctagtaa
     7261 atacattaac gattatgata cgctgtttat caattctagc tcgactgcgt tgaaaacact
     7321 ggattttctt caatctaacc atttgacagt cattacaaac aacgtgaaaa tcaattactc
     7381 tccgcacaaa gataattgta gttatatttt aactggtgga gagatgcgct ttccaaaaga
     7441 agcactagtg ggcgacatcg cattaaatac gatttcttca gtcaatgcag acatttgtat
     7501 cattggctgt agcggagtcg atgtagtaca tggggtcaca acaaagatat taaatgaatc
     7561 aacgatcaac gaaatgatgg tcaacaagac aatcaaatgt aagattttag tcgctgatca
     7621 tcgaaaaatc ggactgacat caaagttcaa gattgctgat atttcagtct ttgattattt
     7681 gatcactgat aaattttgtt ctgaaaaagt attagaggag atcagaaata cggggataaa
     7741 aaccattcaa gtagattcat tttaagaacc aggacgtaaa tatgtaaata ggattatcaa
     7801 aaaaatgaat aacaaattta tcgataaatg aaaaacacgc tacgctcaaa ttgataaagg
     7861 aatcccaaga tgtatccatc caatcgatac catcataatc tattgcttct tttataaccg
     7921 ttatatgttg cctaaatagg aatcaaacaa tatcgaaaaa aggaggtatg acaaaagtca
     7981 cacctccttt tttcgaataa acggtattca aatcagaaca ctgatttcac aaccacttta
     8041 tttcaggtcg ttttcaatca cctttaccgc gtaatcattt ccgttgaaac gcgctatttt
     8101 ttttgcgtcc atatatcttt ctaaataatc atcttctcct aattgcttat ggcaagaagc
     8161 aatttcataa agcaagtatt ccaatgcata agtcgattta tgtttcttat tatactcaat
     8221 acccttctca cataattgga ttgctttatc ataatcctcg attttacggt aataggtggc
     8281 gatatcataa tatacaatgc agaccatcag attatcaaaa tcagtctcac tcaatatttt
     8341 aagtgtacgc tccacataaa ctttcgcaaa atctaattct ccttttgaca agtagatcat
     8401 tgccacgttt gcagctgctt gtaagtgatg gatatctgtt tcggtcgttt gttccaacac
     8461 ttgattaaaa taaaataatg ctgcatctgg ttttttcgca taaagatgat caagcagtcc
     8521 ttgataaaat aaaatttgat ttaaaagatc agaattactt actttttcct gatcgatcgt
     8581 ttgtaaaatt ttataagatt cttggtattt tgatacagaa ttcaatgatt gaatctcatt
     8641 tatttttttc ctgattttgt cttcttctgt ttctactaat atatcggaga tctcgacatt
     8701 cagctttttg caaagcgcac ttaagatatt gatgcctggc gacatattct tgttttcgat
     8761 attgctgaca gttgcttgtt cacaaatgcc ttctgctaat tgtacttgtg ttaacccctt
     8821 tttctttcgg tattctttta gtaatgctcc atctacttta atcaaaacaa tttccttccc
     8881 tttaaaaaat tatttctcct ttatatcata cacaaaaaaa agttctaaac aaccaaaaat
     8941 gtttagaaca gaataaaaat tttaatttta aaataatatt caaattaaac aactggcgta
     9001 tctgctcctt gatttctttt tgtgttatct gaataattat cgtttacagt tataacacat
     9061 agtgaaaatt gtcatggcga gaaagtctaa gaatattttt aaacataact atttctttct
     9121 tacgtgtgta taatgacgac agcacaccta tcaattaata taattatttt atttttttat
     9181 gttctcatgt ttatttttaa tgacacaact tctcgtattt atctggcaca acatataaat
     9241 cgatcaaaaa attgttgcgt gtttttttga aaattggagt ttcaacttga ttacaaaatt
     9301 taaatttaga agttgtgaaa acagcgagag acagtttaat attcaaaata tacataggct
     9361 actcgaacgc tgtgtttttt agtatactag taagaaacga agggatagac tcattccaat
     9421 aaggaggatt tcatgaagac aattcttttt gctcctgcag tattcaattt agctgagaca
     9481 acacgaatga ttgaggttgc caaagctatg aaagaccgtt attactgtgt attctttggc
     9541 ttttctaaaa cttttgctcc tttgatcaca gaaagtggct ttgagtatca tttactagcg
     9601 ccgatcctta cgaaaaaaca agaagaacaa atcataaaat ttgaccagtt gcgtacactt
     9661 aaaaaccctt ttaccaaaga aatggttgcc tctcgtatca ctagtgaaca gagtctgatt
     9721 gctaagtttg agcctcgact gattgtgaca ggttcgaatg tgacaatttt tttatcggcc
     9781 cgcaataaaa agattccttt agtatatgtt aaaccctatg ctttgagtga accttttttt
     9841 caatcagagc atgcgctgat gccccacgag ttacgtttct tcggcccttt aagcaatccc
     9901 ctttggcact ggacaaaaaa gcgtatagta aatacccgat ggatccccaa tgccttcaaa
     9961 cacgctgcac aaaaagaaat gcttccttta ccaaaaacaa gtttacaaat gatggatgct
    10021 gatctaaatc tcatcacaac gcctaaacta tttttggaag aagaacagct gccggaaaat
    10081 tatcgaatcg ttggtccaat ttttgctaag ctcagtactt ccttgcctga agaagtgcta
    10141 acttttatac agcgaaagca acaagaaaga aaacgtatta tctatttcgc aatgggtagt
    10201 tcaggcaatc cgcgtatgtt acgcaaaatt ttgttcttct tacaaaaaca accggatcta
    10261 gcggttattg cacctattga ctatctgctt gatgacattc aatctgactc agaagatctt
    10321 ttaataacag aatatctgtc tagtcatctt ttgcatgaat tcattgattt ttcttttatc
    10381 cacggcgggg aagggaccgt ccaaactgcc tgtgaatccg gcaaaccgtt tatcggtgtg
    10441 gggatgcaat ttgagcaaag ctgtaatatt gactattgtg taaaatacgg aaacgcaatc
    10501 gccctcacaa aaccagtgac tgaaagaaaa ctgcagattg ctctgcgcga agtttcttca
    10561 cccaagattc gtcagcaggc acgcacgctg caagccgttt ttccaataaa tggtccacaa
    10621 caagcaattc aagaaatcga aaccttcctg agcaaccacc caatatagtt tcaagtagaa
    10681 aaagcttttt taatagagac tcatcagtaa tttcgctatt cgagacccag acagtgaaaa
    10741 tacaaaaaaa gtaaatagtg gattgaaaag ttagagttac ttaaattacg gtgtctaaaa
    10801 aacacaaaat catccttaaa ataaaagatc tgacgctatc caaatgagca taggtagcgt
    10861 ctgccattta ttcttagtca aattctttga cacctttctc tggttggatc atctcaacgt
    10921 ttcttcaaaa gaaagaccat aataattagg caaatacatt ttcttaaaat gtgtcatata
    10981 gatctagaag catcgctttg tagagatttg tgccgctagt cccctcaaca attactaaat
    11041 caaatgtagg atttaccact ttatctttga taatcaacct ccctcttctg ttgagacaat
    11101 gatctcgcaa tccgatgcat actcctatat aaactgccag caatccccac atattgagta
    11161 gatcatgtca gaatgttcta tgtcgtcagc aacgatacac taaaagtcac gttcaccatg
    11221 actgattgct attcccagca caattatttc tatacacgtt tcatgatttg aataaacact
    11281 cacatcatac atattaccat tcatacacca tactgcagcc cctactatat ggttgtaagc
    11341 tcccaaatct atatttgact tgatcacttt ggtagtagat ctactaattc taaatccatt
    11401 gctgataaaa tttccatttt ttcctccttc tttctgccaa aacagttaaa acaataataa
    11461 tctttatgta aaaaagggct gtgacaaaag ccttgtcaca gtcccatatt ccgaataaac
    11521 ggtggtcaaa agcttgcatc tgcggtaata agttcaacca aacgaaaaat aagccaacat
    11581 ttcacaaaaa tttaagaagc aattttcgta aatttcttct tatttcttga agctaaccac
    11641 ttctgttaca accactttta gaacatttaa agcttcgatg tgacaaacca tctatgctgc
    11701 tcgatcataa aattgatagc aaaaattcca caaagtacat atgtccccca tgaaaacaaa
    11761 acattcatat gcggtacaat gatctttgga agaatcacga tcaaaaatga tgccagtgcc
    11821 caaatccatc gattgatttg aatatgatat gtagctagca tattcaatat aaggtgacta
    11881 gccgttaata aaaagataaa aacaaaaaat aaaatcagcc aatacattgt ttcccacctt
    11941 ctaaaaacca aacttagaca gtctggactt cgttttctcc acgactttgt tcatctgaca
    12001 gcatcttttt atcataagct tttacaaatg gataatagat aataaatgct atcaatgtgt
    12061 tgatcatgat caagataaca acacgccagt catttcctgc tgaaagataa ccgccgattg
    12121 gagctggtaa tgtccatgtt ggcaaaacag taaatctatt gaccatttct aatttgactg
    12181 caaaataact gataatagtc aaaactaaag gaactaagtt gaacgggatg aacatgtaag
    12241 gattcaacat cataggagct ccaaaaatta tgggctcatt gatattgaag ataccaggaa
    12301 taatagaaaa acgaccaacc tctttcaaga attttgattt acagaagaat ataaacaaaa
    12361 cagataccac gatcgttgct cctgcaccac caattgttac cgtccattga taaaactgtt
    12421 caggagcgat atagggtaat tgggtggcag ctgtaccatc tgccaatgcc tttgcattct
    12481 catccaacat gatcagccac attggacgaa caacagcccc tacaatactc atgccatgga
    12541 taccaaatga ccacaacaaa tggatcaaaa acattggtag taaaacacca agcaaattat
    12601 tccctaaaat attggttaaa ggctcgaata acgataataa ggcagcgttt acatcaaagc
    12661 ccgcgacgct tcgaatcagc caagtaattg ttaaaatgac tgcacctgga atcaatgcct
    12721 caaaactacg ggcaacagca ggtggcactt gttctggcat tttgatagta atatttcgat
    12781 ttttaaagaa acgatatact tccactgcaa aaatcataga taagatcccc gcaaacatcc
    12841 cagatgctcc caaagaactc ataggtaaga cccagccaag aggtgcctct tcaggagtta
    12901 aaacgtttac aggaacttgt aacataaaga acgttcctaa agataatata ccacctgtca
    12961 cactatctaa tccatatgat ttagctagat ccgaacccat aacaaaagtt gcataaatag
    13021 ccatcaatcc catcgtcatc ctaaagggta aaacaatcgt tgccgaataa ggggcaataa
    13081 attcattcca tccaggaaac ggtaaattga taaagaccat aaaaaatgtc ccaatcaaaa
    13141 tcaatgacaa tgttgaaaca accccattac gaattgctaa taaatgacgc tgtgtaccaa
    13201 tttttgccat tggtgggaca agtttctctt cgacccattt catcagcttt tccactaaaa
    13261 ccactccttt tcaataaaat atgaaccatt cattgcatga caacgcaaag aatgttcata
    13321 actaattata taattaagaa attttatttc aatatattct cttaaataat caaatttatt
    13381 tttaagaatc ctgaaaataa gttttctaaa tcataggagc aacaaaaaaa ttcgataatt
    13441 aacaaaaatc aaaatgatta aatctagtga ttgaaacata tcatttcaaa aaaattttgt
    13501 aaattcaccc ataaatatca ccctatttaa cttttttcat cgtacactaa aattcaaaac
    13561 aactatcttt aatctttact tcttggtttt gttttaataa atttccttca aaaatgcctg
    13621 gagaaactac aatgatcacc gtatcttttt gtgcttgctc caacttcttc aaatctataa
    13681 tagctaacag tgtcccttct tttacctcct ggttactttc aacccgtatc tgaaacggac
    13741 ttccttcgag ttcaactgta tctaaaccca tatggatcag tatttttctg ccagattcac
    13801 tttcgatcgt tatggcatgt cgggtaggaa atatattatc gattattcct ttaactggcg
    13861 catggatata tccatcatga ttcgttatag cgtatccaac tcctatcatt tttgaagaaa
    13921 agacctcgtc ttttactgct gttaatggaa taatttgacc actagctaca gcttttagaa
    13981 tgtttcttgt tttaaagaaa tgcacttttt atcacctcta ctttaatgct ggccaatatt
    14041 ttttgtttac tttgatcatt tcatctagta ttttttttgc gactctggca tttggtacgg
    14101 tttgattcaa tgtaaatgct tgtaaagctt tttgataaga accttcaaag taagcatcta
    14161 ctagtaactt ctctactgca acttgtgcct ccatcaatcc tttatgaaaa tcactgattg
    14221 gttttcttag tgtaattggc tccacaccag ttgcaccaac atatgccggt atttcaacaa
    14281 ctgcatctga ccgtagattc ggaatcgccc cttgattagg aacgattagc ataaagcgac
    14341 gacgatcatc attcaacaag gaaatagcta tatcgacgat atattgtcca tgctccccaa
    14401 aattaaagtt caatacttct tccacaatac cgcggcgtat tttatcagcc atttctttgg
    14461 tatttttctc tcgtccatcc atgaccatat tagcacgtgt atactctttg tcagtatgct
    14521 caacgaccat atcaggatat aagtaatact ctaagtaatt attcgggata ttacttggaa
    14581 aatttttcgt gatgactgac atcatttgaa aggttttttg ccaagtttta tctcctatat
    14641 taaaatcggc gacttgcatt tcttttgtta ttagtttttc aataatctct ggcataattt
    14701 ctcgttgcaa ttctttatca taaatcgatg tataccagcc aaagtggttt aaaccataat
    14761 acgtaacgat ccaattctta cgatcataac cgtaattcac tgcaatcgtt tcttcaattg
    14821 aaatagtcat atcacaggca ttaatcattt ttacattcgg atatttacga cgaacagctt
    14881 cagaaacgat cgactctgga tttgtataat tcaaaatcca tgctttgggg gcatagtctt
    14941 gtatatgatc gacaatttcc aataaacctt tgattgagcg catcccataa gcaaatcctc
    15001 cgagtccaca cgtttcttgt cctactaatc catgtttaag tggaatcttt tcgtcctttt
    15061 ctcgcatctc caatcctcca acacgaattt gtgagaaaac aaaatcgcat cctgtaaaag
    15121 caagctttgg atcatccgtt gcacgaatgc gaatatttga aaaacctttt cttttcagca
    15181 taaatttaac aatcaagtac atatccatat ttctttcttc atcaatatca tataaacgta
    15241 tttcagataa tggcaaccgt ttttcattgt tcaaaatggc ttgaacgatt cctggtgtat
    15301 acgtactccc gcctccagct atagtgataa tctgtttttt catcatcatc ttttcctttc
    15361 tattcttcta ataatttatt gaattctgcc ataacataag tcacttctaa gccgatgata
    15421 atttgataat ttttttcagt tggtttaatg atcccgctta tccctaattg cttgattcgc
    15481 tgttcctcga ccatggtggg atccactacc tctacccgta ggcgtgtatt acaactatag
    15541 acatccagga tattggcttt tcctccaaac gcttgtagca tttttgttgc catatattca
    15601 taatttttac ttgctaaccc taactctgtt tcttctaagg ttacttcatt gccaaactct
    15661 gccttagctt cacgtcctaa tgtctgaatg tttctcttat tgatcaaata ataaaaagta
    15721 acgtaataca aggcaaaaaa gaaaattccg attggaagaa tcaaaatagc attggtagcg
    15781 attcgaaaat tgatgagata atcaacaata catgctccga atgtaaaacc aattcgtata
    15841 ttgaataagt aacagacaat ccctgctaaa ccggcaaaaa gtgcatggat cacgtacaac
    15901 ataggagaaa gaaacatgaa actaaattca acaggctcag tgatatttgc aataaatgaa
    15961 gttcctgcac cgcttcccat gattcctttg accatctctt tattttcttt ataagctgct
    16021 ttatagatag ctagacatat agctggtata ccaaacatca ttactacaaa aaaaactgat
    16081 aaaaacagtc cagcctgagg atctccgttg ataaagcgtg tcatctctcc tctgaaaact
    16141 tccttgctag gagatgtata gcttcctaaa tcgtaataaa tatacgtatt caacacatgg
    16201 tgcagtccaa aggggatcag caaacgattc aaaaacataa atatccccac acctaatgct
    16261 cccatatcaa cgagcagttt tgcaaaatta tcaatcccaa tttggatgag cggccagata
    16321 aagcccaaaa aaacagctgc gattgtttgt agaatcatca ccatagtcaa tgggaatttt
    16381 tcgcccgcaa aataagaaaa aactactggt aatttttgtt ctttaaagcg attatacgtc
    16441 catgccgcta ctaaaccgga aataattcca ccaaaaatcc ccatattcac ttctgggtcc
    16501 ataatttcta agcctttttt caaggtagca atcgctaaaa aaccagtaag tgcaggtatt
    16561 cctttgtcct tatttttgac aaaaccgatt gcaactccta tagcaaataa gatatccaag
    16621 tttccaaaaa cggcatttcc agctgcacca attactggga tgttcagcat atcgtcagct
    16681 gataaacgca tgatcaatcc cgctaatggc atcgctgcaa ctggaagtag catcgctctt
    16741 ccaagcttct gcacatttga tttaacattc atttttattc ctcctctatt aaatatcctc
    16801 atatgttact aactcaatca aaggatcatt tttcactttt tgagcaaatg ctgaatgaat
    16861 taaaaattcg acttggtggg tacgaggata cacaaaactt gaaccattta acaattcctg
    16921 atccaaatac gctgcgtgac acatgacttc gatcgtttta tcttctctca atatcatgag
    16981 taaacttgcc aaatattctt ccacactcgt attgatttgt cgtttttttt catcagtttc
    17041 tcctacgaca tcgaaacaag gctcaaaata atcgacatga cgaacttcat cttttcgttc
    17101 aaagttgctc cgaaccggca aatcatattt ttttgctaat gtaacaacta cctcctgatt
    17161 ttcatccaaa gtatgagtat gatgatgact gtctaaatga gttggtatga tccccgcatg
    17221 ataaattttt tgaatctgag cattccattc ctgatacagt tgatctttgt caatgttaaa
    17281 tggatgctga taataagata aggatctgaa ctctccgctt tcgataagag tatcgacagt
    17341 tttgaggagt ggtttgccac acgtcaatgt taaatggact cctacaccta gcctaggcat
    17401 ttcctttctt agtttcacag catgctcgaa acccggcata tttgccatca atgtagttga
    17461 tgtcaaaatt cctcgctgat aagcatccat aatcccataa ttcacaccat ggctatagcc
    17521 aaaatcatcc gaattaaaaa tcacttttcc catttcattc tccttctttt ttctactaaa
    17581 ataggcgcaa ccaaataatc atagtccatt tactatgtgt catttggttg cgcctataga
    17641 tagttacgcc cttattttaa tagattcttg ctagatgaat tgccaaatag atgatttcat
    17701 tttcttgaat ggcaagttga aattgctgtt cgatgatatc tttaatcttt agtgctgtac
    17761 aatacgcttt gctatgttta aatgtttcag taaaaaaacc aatattttct actggcgttt
    17821 cttcctgata aatcaagcgt ttaaccagga atttgatatg aaccattaag cgatgataag
    17881 tcagtgattc tttatcataa acgtttgaat aggatttttc tagatgggac aaaatcgtgg
    17941 tcgtcatttc tactattttt aagctcttta aactattagg ctctcctagc tcagcattaa
    18001 tgatatgcat agtgatgaat cctacttcat ttgaccctaa ctcggtttga tatcgatgat
    18061 tgattcgctc gaccacttct actgctatat catattcatt tggataaagg aatctcattt
    18121 ctggcaacat aattgctgtg acatctctat cttctctttt tcgttgaata gcaaaataaa
    18181 tatgatctgt caatgtaata tagatatttg aatctaatgg agaggagatc ctagctgtta
    18241 tcagttcaat cacttcttcc gcaaaatcca taaattcgat tggaatctgc gagactatct
    18301 cactgaatcg tttgatcttt tctttagaat ctaatacaaa taatttgtca gcatcctcaa
    18361 catcaaatgg cttactcact ttagcagaaa agccaatccc tttccccatc gcaatttttt
    18421 ctattccatc gtcatcgatc aatacagcat tatgattcag ctttttcatc acatacaccg
    18481 ttaattcacc tcctctatat gataaaacaa aacaacttgc agactccttc atacatattt
    18541 ttgtctccaa acaattttta aagacaaaaa acgacctaag aaagaaccct ttcttaggtc
    18601 gtgcctaatt gaatagtagc accctacata atttacaaaa atagtttaac acataataaa
    18661 agcgttatca atatcttttt tactcgtttt atgataatac ttgtatcgaa ttg
//
LOCUS       DBBGSZ010000047        17229 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.049, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000047 DBBGSZ010000000
VERSION     DBBGSZ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.049"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            1..369
                     /locus_tag="ACIZE5_002298"
     CDS             1..369
                     /locus_tag="ACIZE5_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HGC6109411.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            549..1490
                     /locus_tag="ACIZE5_002299"
     CDS             549..1490
                     /locus_tag="ACIZE5_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HGC6109412.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1559..2290
                     /locus_tag="ACIZE5_002300"
     CDS             1559..2290
                     /locus_tag="ACIZE5_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGC6109413.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2434..4614
                     /locus_tag="ACIZE5_002301"
     CDS             2434..4614
                     /locus_tag="ACIZE5_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HGC6109414.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4634..5116
                     /locus_tag="ACIZE5_002302"
     CDS             4634..5116
                     /locus_tag="ACIZE5_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HGC6109415.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            5132..5893
                     /locus_tag="ACIZE5_002303"
     CDS             5132..5893
                     /locus_tag="ACIZE5_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HGC6109416.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            6024..7358
                     /gene="murC"
                     /locus_tag="ACIZE5_002304"
     CDS             6024..7358
                     /gene="murC"
                     /locus_tag="ACIZE5_002304"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HGC6109417.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            7665..8150
                     /locus_tag="ACIZE5_002305"
     CDS             7665..8150
                     /locus_tag="ACIZE5_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="HGC6109418.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            8143..8826
                     /locus_tag="ACIZE5_002306"
     CDS             8143..8826
                     /locus_tag="ACIZE5_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HGC6109419.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGIILAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            8952..11597
                     /gene="polA"
                     /locus_tag="ACIZE5_002307"
     CDS             8952..11597
                     /gene="polA"
                     /locus_tag="ACIZE5_002307"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HGC6109420.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            11642..12478
                     /gene="mutM"
                     /locus_tag="ACIZE5_002308"
     CDS             11642..12478
                     /gene="mutM"
                     /locus_tag="ACIZE5_002308"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HGC6109421.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12442..13071
                     /gene="coaE"
                     /locus_tag="ACIZE5_002309"
     CDS             12442..13071
                     /gene="coaE"
                     /locus_tag="ACIZE5_002309"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HGC6109422.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            13123..13455
                     /locus_tag="ACIZE5_002310"
     CDS             13123..13455
                     /locus_tag="ACIZE5_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGC6109423.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            13767..14258
                     /gene="nrdR"
                     /locus_tag="ACIZE5_002311"
     CDS             13767..14258
                     /gene="nrdR"
                     /locus_tag="ACIZE5_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HGC6109424.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            14281..15654
                     /locus_tag="ACIZE5_002312"
     CDS             14281..15654
                     /locus_tag="ACIZE5_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGC6109425.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            15654..16580
                     /gene="dnaI"
                     /locus_tag="ACIZE5_002313"
     CDS             15654..16580
                     /gene="dnaI"
                     /locus_tag="ACIZE5_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HGC6109426.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            16709..17149
                     /locus_tag="ACIZE5_002314"
     CDS             16709..17149
                     /locus_tag="ACIZE5_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HGC6109427.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
BASE COUNT         5876 a         3009 c         3795 g         4549 t
ORIGIN      
        1 atgtttacga atgaaataaa aatcatgctt tatgtggacg atgtagaaaa aaatgcaacg
       61 ttttggagag cagttggctt tgcggaaaaa gatcgtcaag aaatggatgg gacgcttata
      121 attgaagtag gagttgagga cagtcaaacc tcatttctgt tatatgatcg agcatttgtt
      181 gagtcccatt cacctggcac agctactagt gccccatctt tgatgtttta cagtaaagat
      241 atctttggac tatataaaaa aatgcagacg caatcagtca cattaggtga tatggtacag
      301 cttggagaag aatatgtctt taactttgct gatcccgatg gcaactactt tgcggttaca
      361 ggtaaataat agaaataaag actttgtttt tctgtgcgaa acaggaaagc gaagtctttt
      421 taattcaaat aataatatta tgtaaacaaa aaactttcca tgcgtaatta tacacaagca
      481 aataaatcgt caaatgcgaa cgccttcttt atactgttta ggaacgaaaa gaaggaagga
      541 agaaatacat ggattatcaa gtactgcttt attacaatta tacaaaaatc gaagaaccag
      601 aggaatttgc caaaaatcat ttagcctttt gcaaatcttt ggatcttaaa ggtcgtattc
      661 tagtagctga agaaggaata aatggtactg tgtctggaac cgttgaaaac acgactgcct
      721 atatgaaagc aatgaaagct gatcctcgat ttgctgatac gatgttcaag atcgatccaa
      781 gcgaaggaca tgcctttaag aagatgtttg taagataccg tccagagctt gtaagtttaa
      841 agctagaaga ggacattgat ccaaaccaag tgacaggtgc ctatctttca ccgcaagaat
      901 ttaaagaagc tattttagat gaacagacag tggtgattga tgcacggaat gattatgaat
      961 atgacttggg acattttcga ggggctgtac gcccagatat acgcagtttt cgagagcttc
     1021 cagactggat ccgcgagcac aaagaagaat ttatggaaaa acgggtagtg acctactgta
     1081 ctggtggcat tcgttgcgag aagttttctg gttggcttgt ccgtgaagga ttcaaagatg
     1141 tcggacagct gcatggcggt attgctactt atggtaagga tcctgaagtc caaggagaat
     1201 tatgggacgg caagatgtat gtgtttgatg aacggatcgc tgtcgatatc aaccaagtag
     1261 ataaacaaat cgtcggtcgc gactggtttg acggaacacc atgtgaacga tatatcaatt
     1321 gtagcaatcc tgagtgcaat cgtcagattc ttgcttccat tgaaaatgaa gaaaaacatt
     1381 taggagcatg tagcatagag tgtgcgaaac atccgcgcaa tcgctatgtt caagaccatg
     1441 gaatctctcc agaagaagca gaactgcggt ttacagcttt aattaaatag aaaacaatag
     1501 ttttgattgt cgaccatttc caatatgcgc tatactagcg ttgaggatgg tgatccacat
     1561 gaaatcattg atttatgcta ttggggatgt ccatggcaaa catgagcttt ttgaaaaact
     1621 tattcactat tatgatccaa agatccatca gcttgtttta ttaggggatc tcaatgatcg
     1681 aggtcctcgt acaaaagaat gttttttatt aggaaagcaa ttagtcgaag aaacaggagc
     1741 catttacctc cggggaaacc atgaagaata ttttttgcaa tttctgcaat caccggagga
     1801 ctggtatgcg ccttatatga gaaatggtgg aaaagaaacg tttgaaagcc tgattcaccc
     1861 aggggcatcg gaggaatact ccccaactga aatctcgatg atgatccaat cgagatattc
     1921 agaactgatt aaatttttag tccagcgccc cttgtattat gaatgggaaa attatctttt
     1981 tgtccatgcc ggtgtggatt tgacaaagaa agactggcgt aagacaagtc taagagactt
     2041 tatttggata agggaaccat ttcatgaagg gaaaaacaat acaggtaaga caattgtatt
     2101 tggacatacg attacaccaa tgctccatgg agatatgcag acaacagacc tctggattca
     2161 ggatcataaa atcggaatgg acggtggggc tgtattcgga gggtcattgc atggggttgt
     2221 ttttgacaag gaaggtattc ttcaagatat tgaatatcag aacaacgaag gaccttggca
     2281 tggaatctga ctaatggaaa gaatgaagga gctgtgactt tgttgcggct ctttttattt
     2341 ttatagagaa tattgtttct ttcagtagtt taacccagga taaaaagtat gatagaataa
     2401 agaagcaatt tttagcagaa aagaggcatt ttaatgacgg aaaatttgaa ccagacgatc
     2461 attcagcttg tacaaaaaga actttcagac tatcgtccta agcagttgac tactgtactt
     2521 aatttgttaa atgaaggaaa cactgttcct tttatcgcgc gttaccgaaa agaaatgact
     2581 ggaagtcttg atgaagtcca gattcgtgaa atcgaagagc ggtatgccta tcttgaaaac
     2641 ttagaaaaac gtaaaactga agtgattcgg ctaatcgatg aacaagggaa actgactccc
     2701 gagttagaag cagaaatcac ccaagccgtg aaaatgcaac aagtggaaga tttgtatcgt
     2761 ccatacaaac aaaaacgacg gacaaaagca acgattgcta aagaaaaagg acttgaacca
     2821 ctcgcgaagt ggctgatgca gcttacagat ggagaggtgc aatctgaagc agaaaaatat
     2881 attgacaaag aaaaagaagt ctcttctgcc gaagaagcgt tgcacggtgc tcatgagatt
     2941 attgctgaac aagtcagcga taatgcaaaa tttcggactt ggattcggtc ttatacgtat
     3001 aacaaaggta tgtatgtcag caatgtcaag gatgagcaag cagatgaaaa aggcgtatat
     3061 gaaatgtatt atgactttgc agaacccgtc cataaaatgg tttctcatcg aatattagct
     3121 actaatcgtg gagaaaaaga agatattctg aaagtattct ttcaagtaga tgaagcagca
     3181 attttagctt acttggatcg ccaaatagtc aaaaatcctg cctctccttc ttcttcattc
     3241 gtcagagaag cctatcagga tagttataaa cgctttattc agccagcaat cgagcgagaa
     3301 ctgcgcaatg aattgactga aaaggcagat gagcaagcaa tcgctatttt cggcgaaaac
     3361 ctccgtaatc ttttgttgca accgccacta aaaggtaaag ttgtcctggg atttgatccg
     3421 gcttatcgta ctggatgtaa actagcagtc gtagatgcga cagggaaagt tttagcaatc
     3481 gaagttattt atcctcataa acctgcagcg caagcaaaaa gagaagctgc tggaccagct
     3541 tttatccaat taattaataa atatcaagta gatatggtag ctatcggaaa tggtacagcc
     3601 agtcgggaat ctgaactttt tgtggctgag cagttgaaat ccgccgacca taaaacctat
     3661 tacgctatcg tcaacgaagc aggcgcttct gtttactccg ctagcgaaat tgcacgaaaa
     3721 gaatttccgc atctacaagt tgaagaaaga agtgctgttt ctattgcccg tcgcctgcaa
     3781 gatcctttag ctgaattagt caaaatcgat cctaaagctg tcggagtagg ccagtaccaa
     3841 catgacgttt ctcaaaaacg tttggctgaa caattggatt ttgttgtgga aacagcggtt
     3901 aaccaagtag gtgtggatgt gaatacagca agcccgcagc tcttgcagca tatatcagga
     3961 ttgaataaaa caactgccca aaacattgtc atttatcgtg aagaaaacgg agaattcacc
     4021 gcacgaactc aattgaaaaa agtgccacgc ttaggaccaa aagcatatga acaagcaatc
     4081 ggattcttgc gagtccctgg tgggaaaaac attttggaca acacaggtat ccatcccgaa
     4141 agttattcta ttgcaaaaga aatattaact tcagtccaac tttcagaaaa agagcttggt
     4201 acagaagaag cagtagaaaa attgacacga ttatccgtag agaaactggc tgaaagccta
     4261 tcagtcggag aagaaacgtt agccgatatt ttagctgggc tgacacaacc tggacgagat
     4321 atgcgtgatg agatgccagc gcccttatta cgtacagatg tattgagtat ggaagacttg
     4381 aaaccaggga tggaattgac tggaacggtc cgtaatgtca ttgacttcgg cgcatttgtt
     4441 gatatcggtg tgaagcaaga cggacttgtc catatatcga aactcagcaa aaaattcgtc
     4501 aagcatccta cagatgtcgt gtcagtagga gatatcgtaa cagtttggat agaacaagtc
     4561 gatacgaaaa aaggcagaat cagtttgacg atgctttccc cttatgaaga gtaacaatga
     4621 ggagtaacaa aaattgacac aagaagaact gcagcagtta gtagaagaga tatcattaaa
     4681 aagcttccag cttcctttca agcaccaagc aatgttcaat ccacgcttac gtacaactgg
     4741 cgggcgctat catttaaacg atcatcattt agattttaat gcgaagctat ttgaagagtc
     4801 agacgaagag acgattgcag gaatcatcaa acatgaactt tgccattatc atcttcatct
     4861 agctggaaga gggtatcagc ataaagatat ggatttcaag tatcttttga aaaaaacagg
     4921 agggttgcgc tatgcaccag ccttgacgaa gaaacagata aagatggagt attatcgatg
     4981 ccaagattgt tctgccacga tctgccgcaa gagaagaatc gatgtacgca aatatcgttg
     5041 tggaagatgt catggagaaa tcaaatggat tgagacaaaa agagaagact ttaatgaagc
     5101 acaaaaaatc agatgaaagg atagaaggcc tttggaaaaa agtgagcaga ggaatctaaa
     5161 agactggaat cagctattaa attttttagc cgcacctgaa gagggaaatt ttgaggaact
     5221 gacggcacct acacttattt tagctggaaa ctgtcttcct atcttagctg ataaagcagc
     5281 acaaatgtat ttaaatggcc aagtagatca attgtttttg gtcggagggg tggggcatgc
     5341 gactagaatc ctttatgaga attttgaaaa gcaaggattt cattttgaag atggcatgag
     5401 tgaaagtgaa atctgtcgtc agtatctaaa agaagtctat gatttgcccg ataaggcttt
     5461 tctgatagaa tcgaagtcta caaattctgg agagaacgcc actttttcac tggagattct
     5521 tcattcctta ggagctgtac cagaaaaaat cttattgatg aatgatccga cactgcaacg
     5581 caggactcga gcaacttttg agaaagtatg gcaaaatgaa caaactattt tcgcgaatgc
     5641 tgtgccattt gtgccggaaa tccttcactt ttctgaagag atcatcttta cagcaaaaga
     5701 actgaatcat caatggccta aggaatattt ccatgcgcta gtattaggag aaatggaacg
     5761 tctccatgac gatgagaacg gctatggtcc gaaaggaaaa gattttattc ctcacattga
     5821 tatatcagag gaagtttggt cttcttacac cagaattaaa gagtcaataa aaacggattt
     5881 ttctcgtact tgaccatttt agcaagcgaa tcctcctttc caaataaatt tggttgaaat
     5941 tttcaatcgt ttataagata atgaggagcg tgttgaatgt aatagctaaa agaatggacg
     6001 ctagataaga gaagaggatt caaatggaaa atcaaaataa attgtatcat tttgttggta
     6061 tcaaaggttc aggaatgagc tccttggctc ttgttttaca tgaacaaggt ctaaatgtcc
     6121 aaggatcaga cattgaaaaa tatttcttta cacaaagaga tttagaaaaa gcaaatatca
     6181 cgattctgcc atttaacgca gataatgtaa aaccagggat gacgatcatt gcaggaaatg
     6241 catttcctga ttcacatgaa gaaatccagc gagcaaaaga attaggtttg gaagtgattc
     6301 gctatcacga ctttattggt cattttatcc aaaattatac gagtatcgct gtaacaggct
     6361 ctcacggaaa aacaagtacg actggactgc tctctcatgt attgagtggt gtccgtccaa
     6421 caagttatct aattggagat ggaacaggac atggtgatcc gcaagcggaa ttcttttcat
     6481 ttgaggcctg tgaatatcgc cgtcatttcc ttgcctattc accagactat gcaatcatga
     6541 ccaatatcga ttttgatcat ccggattatt atacaagtat cgacgatgta tttacagctt
     6601 tccaaacaat ggctggacaa gtgaaaaaag ctatttttgc gtatggtgac gatgcttatt
     6661 tacgcaaatt aaaagcaaat gtgccgattt attattatgg tgtcacagaa aacgatgata
     6721 tccaagcacg aaacatcgaa cgcacaactt ctggttctgc ttttgatgtc tatcatgggg
     6781 atgaatttgt tgggcacttc actgtaccag cattcggtaa acacaatatc ttaaatgctt
     6841 taggtgttat tgcagtagct tatttcgaaa aactggatct gaaagaagtt gcagaagaaa
     6901 tgctgacttt cccaggagta aaacgtcgat tcagtgaaaa gatcgtagca gacatgaccg
     6961 tagtcgatga ttatgcgcat caccctgcag agatcaaagc aacgattgat ggcgcacgcc
     7021 aaaaatatcc agataaagaa ataattgcag ttttccaacc ccatacgttt acgcgtacga
     7081 ttgcattgat ggatgaattt gcagaagcac ttgatttagc tgataaagtt tacttatgcg
     7141 atatttttgg ttcggctcgg gaagaacaag gaaacgttaa gattgaagac cttggagcga
     7201 aaatcaaaaa aggtggagaa gtcatcaaag aaaataatgt atctccattg ttagattatc
     7261 atgatgcagt agtaatcttc atgggtgctg gagatgttca aaaatttgaa caagcgtatg
     7321 aaaaactttt aagcagcacg acgaaaaatg tactgtaata caattactgc agtgtcctta
     7381 taaaaataga aagaggggga gtggcaaaaa tcttgccaag cccccttttt tgcaacttat
     7441 gataaacggt gttcaaaagc ttgcatctgc ggtaataagc ccaatcaaat caaaaacatg
     7501 agaagctgtt ttttcttggc tgttcttatt atttgatgca ggacagcttt ttcacgacct
     7561 ctgtaaacta taggaatctg ttaaatcaag ggagcagaac ttgcctttta cgctactttt
     7621 ggtacaataa tgtatgatta aaaataaact ggagggtttc tatcttgaac ataggtaagc
     7681 cgagaaaact aggaaaaaca ataaatgaaa tcgaggaagg cgactcgtta tccttaacag
     7741 aatctattga agataaccag cttttgctgt atttgggatt gacgaatgat gcaaatcctt
     7801 tgtatatcca acatgacttt gcacaaaaaa cagaatatca acagccaatc gttccatcag
     7861 tgatgctgat ggggatcatc acaagtgcaa tttcaaagca tcttcctgga ccaggatcac
     7921 atgttgtcaa tttttctgtc aattttattg aaccggtttt ccattatgaa acactgactt
     7981 ttcagtttga ggtcataaaa gtagataaga tgaaggatgt ggtgacgatt tctgtagaag
     8041 cggagaatac gaacgaagat cgtgtgttgg atgctgtcgt tatggtccaa ccgccacaag
     8101 ttcctgaatt ggaaatagca atcgaaagtg aaggtgaatt gaatgaataa tccaagtaca
     8161 tcaatgtcag gtatcaatcg tttttatgca aaagtttatg gatttttagg tatgggactt
     8221 gcccttagtg cagtcacttc ttacttggct ctttgggtat ttcctttgca attagcaact
     8281 tttatcaata attttccact aggctttgtg ggtctgtgga tcgttgaact gattttagta
     8341 atggttctag gcgtaaaagc acaaaagaat ccgagcttag caatcggtgg atttattgcc
     8401 tactctcttt tgaatggcat aatattagcg gttactcttg catactacga tattggaaca
     8461 gtaacgcaag ctttcttgac agctactttg atgttcatgg ggatgtctgt tgtcggagta
     8521 acaacaaaaa gagatcttag cggggttgga agagcaggac aggcagcttt aatcggagtg
     8581 atcattgcac tagtcttgaa catcttcatt ttgagaagta gcgtagttga gctgttcatc
     8641 tccctactgt tagtcgtcat ctttgcaggg attacagctt atgataacca aagcatccgt
     8701 aatatctatg tccagacaaa cggaacagca catagtggaa ttgctgtatt catggcattg
     8761 aagctgtatt tggactttat caacttgttc ttggcgtttc tgagaatctt tggacggaac
     8821 aactaaaaaa gaaaaaaatt catcagttgg ggctataccg aattatttgg tatggtcccg
     8881 ctttttcttt tcgcattccg caggattctt tgttagaatg aataagaact ttacagtaag
     8941 gagttaagaa gatgacaaaa aataaattat tactcgttga tgggaacagt gtggcttttc
     9001 gcgcattctt tgcgcttcac aattctcttg aacgtttcaa aaatagaaac ggtcttcata
     9061 caaatgcaat ctatgcattc aatacgatgt ttgaaaatgt tatgcaaaaa gagcaaccga
     9121 ctcatgttct ggttgcgttc gatgcaggaa aaacgacttt tcggacagaa atgtatgcgg
     9181 agtacaaagg tggaagatcc aaaacacctg gcgaattcaa agaacaaatg ccatatatac
     9241 gtgatttgtt gacaggacta ggggtacagt attacgaatt gcccaattat gaagcagatg
     9301 atattatcgg tactttggca gaaaaagtag acaaagatca atttgatgtc gtcgtgcttt
     9361 caggtgatcg ggatttgact caattagcta gtaaagaagt aaaagtggat atcactgtaa
     9421 aaggtgtcag cgatatcgaa agctatacac cagaacatgt agcggaaaaa tatgatgggt
     9481 tgacgccaaa acagattatt gacatgaagg gactagccgg agatgcctct gacaatatcc
     9541 ccggtgtgac taaaatcggt gaaaaaacag ctatcaagct attgaaacaa tatggctcag
     9601 tcgaaggaat ttatgaacat atcgatgaaa tgaagcaaag caaaatgaaa gaaaatctga
     9661 taaatgacaa agagcaggct ttcttatcga aaaaattggc gaccatcaat acttcagcgc
     9721 ctgtggatgt ctctatcgac tcattgaagt atgaagggaa aaatctcgat aaactcgttc
     9781 cgttttataa agaaatggat ttcaatcagt tcctttctaa attgaatatc gtagaagaag
     9841 aagtaaaaat ggatgatatt ttgtttgaag tcgttcatga attcaaagag gaaatgttta
     9901 ctacggatat ggcgttgtac gtggaaatga tgggcgacaa ttatcataca gaggaaatcg
     9961 tcggagtagc gtgggggaca gaaaagaaaa tttatgtcac gaacgatcta tctgtattcg
    10021 aaaaccgagc gttccattct tggatcactg atccgactcg gctgaaaaaa gtatatgatg
    10081 cgaaacgaac ttatgttgct ttaaaccgct atactggaaa aacgaaagga atcgattttg
    10141 atgtcttgct aggtgcatac cttctcgata cgaatgaaaa aagcacagat atcgaaggaa
    10201 tagctgctca ttacggatac aacgatatcc aatcagatga agctgtatac ggcaaagggg
    10261 cgaaaaaagg tttaccagaa gaagaggaac tcttttttgc tcatttagcg cgaaaagtag
    10321 ctgcaatcaa tgcgttgaca ccaaaattga gccaagaact ggcagaaaaa aaccaagaag
    10381 atcttttccg gaaaatggaa ctgccattgt ctatcatttt ggcagagatg gaaataagcg
    10441 ggatcaaagt agatgcgact cgcttacaag aaatgaaggg cgagttctct gctcgcttaa
    10501 gagagatcga acaaaaaatc tacgaagaag ccggcgaaga attcaatttg aattcaccaa
    10561 agcaattagg agtgatctta tttgaaaaaa tgggattacc cgttatcaaa aaaacaaaaa
    10621 ctggatattc cacagccgta gatgtactgg aacagcttcg tgaacaagca ccaatcgtag
    10681 aggatatcct cacctatcgt caaattgcaa aaattcaatc tacctatgtc gagggactgc
    10741 tgaaagtgat ccaatcagat ggaaaagtgc atacccgtta tgtccagaca ttgacccaaa
    10801 caggacgatt aagctctgtt gatcctaatt tgcagaacat cccgattcga ttagatgaag
    10861 ggagaaagat acgtcaggca tttgttccta gagaaaaaga ctggctgatt tattcttctg
    10921 actattcaca aatcgagtta cgcgtacttg cgcatatctc aaatgatgaa catttgaaag
    10981 ctgccttcct agaaggtcaa gatatccatg ccagcacagc gatgcgtgta tttggaatcg
    11041 aaaaggcaga ggatgtcaca ccaaatatgc gtaggcaggc aaaagcagtg aattttggta
    11101 tcgtgtatgg catctctgat tacggacttt cacaaaatct aggaatcagc cgaaaagcag
    11161 cacagcaata catcgatacg tactttgaaa aatacccagg tgtcaaagaa tatatggaaa
    11221 gaatcgtacg cgaagcaaaa gaccaaggct acgtcgaaac gctgtatcac cgccgtcgat
    11281 atctgccaga catcaattca agaaattaca atatccgttc ttttgcggaa cgaacagcta
    11341 tcaatacacc aatccaagga agtgctgctg atattttgaa aatcgcgatg atcgaattgg
    11401 ataaacgatt aaaagaaaca ggtcttcaag ctacgatgct gttacaagtt catgatgaac
    11461 ttgtcttcga ggtaccggaa aaagaacttg aatcattaga taaattggtg aaggaagtta
    11521 tggaacaagc tgtttctctt catgtaccac tgatcactga cagcagttgg ggaaaaacgt
    11581 ggtacgaagc aaaataaaca ttgtttaaga cagagcaata taatgaaggt gaaaagaaaa
    11641 aatgccagaa ttaccagaag tagaaaccgt tcgtaaagga ttggaacggt tagtagtagg
    11701 aaaaacgatt caaaaagttc aggtcttgtg gcccaagatc atcgagcaac cagagacacc
    11761 catctttgag gcttctcttg ttggcgaaac catccaatcc attggacgta gagggaagtt
    11821 tttaattttt catctcgatc attgtgaact gatctcacac ttgcgaatgg aaggaaaata
    11881 tcaatttacg aaagaaaata caccaatcga taaacatacg catgtacttt tcttttttga
    11941 ggatggaagc caacttcgct acaacgatgt acgaaaattt ggtcgtatga caatcgtcga
    12001 aaaaggagca agtgcaactt accgaggaat catgaaattg ggacctgagc ctttgccaga
    12061 tagcttctta ttagcagatt tcgcaaatgg actgaaaaag tcccacaaag caatcaagcc
    12121 attgctgcta gaccaacgtc tagtgactgg tctaggtaat atttatgtag atgaagcatt
    12181 atgggaagcg aagatccatc cagaacaacc ggcgaacaca ctgcgcccca aagaggtaga
    12241 acaattacgt ctatcgatca ttgatgtttt ggatcgtgca atagaagccg gaggtaccac
    12301 gattcgcagt tatttgaatg cattaggaga atcaggcgga tttcaagtag cactgcatgt
    12361 ctatcagcaa actggcaaac catgtatacg ttgtggaacg ccgatcgtga aaacaaaagt
    12421 ggcacaaagg gggacgcact attgtccgaa ttgtcaaagg ctaaaaatcg caaagtagga
    12481 tttgttttag gtttgacggg tggaatagct accggtaaaa gtacggcagc caaagtcttt
    12541 cagtctcatg gatttccttt gatcgatggc gatgtgattg ccagagaaac tgttgagcct
    12601 ggaacgcttg ctctgaggaa aattgtatca gtgtttggcc aagaggtatt gcagcctgat
    12661 gggcaactag atcgagggaa acttgggatg attgtttttc catcaaagga aaaacggcaa
    12721 aaacttgatc agctattaga tccgtttatc cgaaaagcga taaaagatca aatcgcctct
    12781 ctaagttcca atcatccttt agtaattgta gatatcccat tgctctacga aggtcattat
    12841 gaccactata tggatgcagt agctgtcgtt tatactacgc cagaaactca gcttcagcgt
    12901 ttgatgaaac gtaatcaact gacgctagaa caagcgcagc agagaattag tagtcaactt
    12961 ccaatcgaag aaaaaaagca gcgtgcggat attttgttcg acaacaatgg aacaaaagaa
    13021 atacttgtgg gacaaatcga aaattggctt tttgctaatc gctttctttg agtatctgtg
    13081 tcaattttgc tatcctgagt atatagaaag tgagggatag cgatgggatc attaaaaaat
    13141 caaaaggata aagtcgtagg taacgcaaaa gaaaaaatcg gcgagatgct caataaagaa
    13201 aatctaatcg atgaaggtcg tacgcaatca gaaacagcag aagaaaaaga aaagcagtac
    13261 caagcaagaa tcgatgaaat agaagaccag caggcagaag aagaagcgaa gcggcaagat
    13321 ttgactcaag aacgaaaaaa tccgacacct gatcgtagta aaacaccgct cccagaaagt
    13381 gaccacattc ccgatgagca aaaaatcgag gaacagcgaa tgaaacacta tacaggaatc
    13441 gaagagaagt tataaaatag taaaaaatcg agatgtgact tgaagcagat gagaaggtgt
    13501 tcatctgctt caagtttttt gtgctagatg actaaatcag cttttgtgta agttatttct
    13561 cagtaatcaa ggtgatcagt attggaaaat tgaaatttag taaggacagg ggacacaatt
    13621 acgcatgaaa gtagaaaaaa ttgttcttat atccgtgttt tttgggtagg acagtcgcgt
    13681 ttgtgatttg tttcgtgtta taatacaact agttgtaaag aaagacacat cctttatata
    13741 aaatgcgatg caagaggtga gacaaaatga gatgtcccag atgtcaacat aataattcac
    13801 gagtaatcga cagccgtcaa gcagatgatg gacgtgcgat ccgtcgccgt cgcgaatgtg
    13861 agaattgttc gttccgattc actacatttg aacgaattga agctgctccg ttattagtaa
    13921 tcaagaaaaa cggggaacgc gaagagttca atcgcgataa aattttaaga ggactcatcc
    13981 gttcagcaga aaaaagacct gtagctatgg aacaaatgga acaaatcgtc aaccatgtcg
    14041 aaaaccgcgt acgcagtctc ggagaaaacg aagtatcgac gaatctaatt ggtgaatatg
    14101 tgatggaaga tttagttgat ttagacgaaa tcgcttatat tcgttttgca agtgtttatc
    14161 gccagttcaa agatatgtct gttttcttaa aagagttgca agatatcgtg gataaagcaa
    14221 aagaaaataa taaagagaat aataaagaaa acaattaaga aacaaaaagg aggcatttcc
    14281 ttggaaaatg cttggaaaga gcttcaacca aaaaatattt accaaggaag aaaagcggct
    14341 ccgctgagag aagacagcaa gaacgccttg ctgtatcttt atcagccact aatcggcgga
    14401 gaagccttga gtatctattt caccctgtta tcagaaatct ctcaagaatc tggcaaaggt
    14461 cctgaaggga tgcatgcaga tctgcttagt agtctaggct gcggtatccc gcaattttat
    14521 gatgcaagaa aaaagctaga aggaatcggc ttactggatg tttattttaa agaagatagt
    14581 gatctgggac ctcgttttat ttatgagctg ttagaaccac tcattcctaa agcatttttc
    14641 aaagactctg ttctggcttt tcttcttctg gaaaaagttg gtgaacgacg attccagaag
    14701 cttacccaat tctttgaacc taaaaggcat acagcagagg gatatcaaaa aatcacaaaa
    14761 aaatttttag atgtttatcg cttcaatgaa gcagtgtacg ctgctaatca agaaaacatc
    14821 gaatcgctga ataaatcttt tgaagaatct gaatcagtag cattacttga agcagattcg
    14881 acattcgatt ggcagttttt gaatgattgg ctggcaaaaa aacatattgc aagtcttgat
    14941 gatccaatca tcaaacaagt cgacatgtat catcagcttt acggtttcga tgaattgaca
    15001 cttggcgaac tgatcagtca atcttatgac tttagtgaac aaaaagtatc tgaaaaagaa
    15061 ctgcaaaaag ccattttggc aatgcagaga cgtccggtga agcaaacaaa agaaacagtt
    15121 gcggtttctg aaaacagtaa tgaaccctcg tcaaacgaac atttgacaaa cgcagcgctt
    15181 cagctgataa aagaagcaca gagcattcca ccgatgaaat atctggaagc aatcaagtca
    15241 gaaaaaggcg gatatgtttc taaacaagaa aactggttac tgcaagatct tgtttctcaa
    15301 tcaggtcttt ccagtagcgt gatcaatgtt ttgctgaatt atgtactagt gatcaagaat
    15361 aatgctagct taaatgccag ttatgtaaat acagtggcaa atgaatgggc acaaaagaaa
    15421 atcgccacag cagaagaagc gatccagcac attcggcaaa taagtaatca agcaaaacaa
    15481 tcaaaacaaa agaagcaaac aaattatcaa actggcaagc gaaatgttcg acgggaaaag
    15541 cttcctgatt gggtcaacca gccaaaagat gaaaaacaga tcagcagcga gaaaaaagca
    15601 gagattgacc gccgttttaa agaatacctg gcaaaaaagg agggtgatat ctagtggaag
    15661 acgtaggcaa agaattgaag aggatcatca gcaaacgcaa ttatcaagaa aagtatgctg
    15721 aaatgatcgc tgaagtctta aatgatgcgg atgttcaagc ttttctaagc gcacaccaag
    15781 aagaattgac acaagcggat attgaaaaaa gttacgctaa attgtatgaa ttcgtgcaag
    15841 aaaagcgtaa atatcaaaaa aacgatccaa cgatgatcgc tcccggctat gagccgaagc
    15901 tgacgttgaa ttttcattat gtggatgtca cttatgtacc aacggaagca ttgttagcac
    15961 ggcaaagaca agaagaaatc agaagccgag taaaagcaat ggatatgcca aaagatattc
    16021 aatcggcttc ttttgaaaac tttgaacgta cagatggacg aggatatgcg agcttagaag
    16081 ccctagattt tgtagagaaa tatactgctg atccaaaagg gtatcataaa ggactgtatc
    16141 tagtaggaag ttttggtatt ggaaaaacat atttattagg agcaacagcg agagaattag
    16201 cgattgctgg attcaccacg acgctagtcc attttccgac atttgccgtt gagatgaaac
    16261 aggcaatcgg aaaagatcaa gtggcagaaa agttagatgc agtgaaacgt tcacctattt
    16321 tgatgatcga tgacattggt gcagatgcga tgagtagttg gatacgagac gaagtattcg
    16381 gtgttatcct tcaatatcgg atgcaggaac agttaccaac cttcttctca tcgaatttta
    16441 caatggatga attggaacag catttgtccg tcactcaacg tggagatgaa gagccgctaa
    16501 aagcgaaacg gataatggaa cgcatacgtt atttgacaaa agaaatcgaa atgactggtc
    16561 gcaaccgacg caatggttga acagttgaca agtccaactg acatttgacc tagtagtaaa
    16621 agcaggtcag cgaatcatta tatggacaga aatgaccgga gacaatcacc gcaacaagta
    16681 atgcagaaac ttaaacggag gattttttat gagggctatt ttttctagta tatctgtagt
    16741 tggtctattt tttcttttag caggctgcgg tagcgcagat agcaacacag gttctgttga
    16801 ttcgattgat gcgggtcaaa cagtaaaaac aagcagtacg aaaacggaga gacaaagcat
    16861 atttgtcgga acgattgaaa gtatcactca agtagaagca gaagaagaaa cgcttcagtt
    16921 gaaactcgtc gatgtcatgg ccaaagaaga tccagcgaat atgggaacgt cattcagcaa
    16981 tgacggagtg atcttaaatg ctactgctga aaaaataagc gtggacataa atgaattgaa
    17041 aatcggtgac aaagtccaat ttacattagt tgagatgccg atcatgacga tgtctatccc
    17101 accgcaagtt cctggagatt cgattattga tgtttcattg aacaaataac caataacatt
    17161 ttttcaaaaa taagaaaatg ttgttttata gaacgaaaag gtatattttt taaggagata
    17221 tgggaattt
//
LOCUS       DBBGSZ010000048        17106 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.050, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000048 DBBGSZ010000000
VERSION     DBBGSZ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17106
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.050"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            7..1398
                     /locus_tag="ACIZE5_002315"
     CDS             7..1398
                     /locus_tag="ACIZE5_002315"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGC6109428.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            1414..2454
                     /locus_tag="ACIZE5_002316"
     CDS             1414..2454
                     /locus_tag="ACIZE5_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGC6109429.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            2473..3558
                     /locus_tag="ACIZE5_002317"
     CDS             2473..3558
                     /locus_tag="ACIZE5_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HGC6109430.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            3591..4553
                     /locus_tag="ACIZE5_002318"
     CDS             3591..4553
                     /locus_tag="ACIZE5_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HGC6109431.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            4546..5973
                     /locus_tag="ACIZE5_002319"
     CDS             4546..5973
                     /locus_tag="ACIZE5_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HGC6109432.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            5975..7045
                     /locus_tag="ACIZE5_002320"
     CDS             5975..7045
                     /locus_tag="ACIZE5_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysialyltransferase family
                     glycosyltransferase"
                     /protein_id="HGC6109433.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            7032..8453
                     /locus_tag="ACIZE5_002321"
     CDS             7032..8453
                     /locus_tag="ACIZE5_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGC6109434.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            8466..9473
                     /locus_tag="ACIZE5_002322"
     CDS             8466..9473
                     /locus_tag="ACIZE5_002322"
                     /EC_number="4.2.1.115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050377 - UDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4,6-dehydratase family
                     protein"
                     /protein_id="HGC6109435.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            9485..10489
                     /gene="neuB"
                     /locus_tag="ACIZE5_002323"
     CDS             9485..10489
                     /gene="neuB"
                     /locus_tag="ACIZE5_002323"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0016051 - carbohydrate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HGC6109436.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            10486..11634
                     /gene="neuC"
                     /locus_tag="ACIZE5_002324"
     CDS             10486..11634
                     /gene="neuC"
                     /locus_tag="ACIZE5_002324"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0006047 - UDP-N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HGC6109437.1"
                     /translation="MKKILIVSGTRADYGVYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            11607..12284
                     /locus_tag="ACIZE5_002325"
     CDS             11607..12284
                     /locus_tag="ACIZE5_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HGC6109438.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            12235..13416
                     /locus_tag="ACIZE5_002326"
     CDS             12235..13416
                     /locus_tag="ACIZE5_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGC6109439.1"
                     /translation="MAIQLKLRKKELILNSRILLSSPHMGGTEEKYVAKAFKDNWIAP
                     LGENVDKFEESITKYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATV
                     NPILYQGAVPVFIDSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYER
                     ILAIANQFNVPVIEDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSD
                     KKYVEHSRFLATQARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIF
                     NRYKEAFSGIDRIEMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRA
                     LWKPLHLQPVFQGVKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIF
                     K"
     gene            13429..14406
                     /locus_tag="ACIZE5_002327"
     CDS             13429..14406
                     /locus_tag="ACIZE5_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC6109440.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            14406..15314
                     /locus_tag="ACIZE5_002328"
     CDS             14406..15314
                     /locus_tag="ACIZE5_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HGC6109441.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            15315..16067
                     /locus_tag="ACIZE5_002329"
     CDS             15315..16067
                     /locus_tag="ACIZE5_002329"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HGC6109442.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            16072..17019
                     /locus_tag="ACIZE5_002330"
     CDS             16072..17019
                     /locus_tag="ACIZE5_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HGC6109443.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT         6161 a         2191 c         3092 g         5662 t
ORIGIN      
        1 gtatatatga ataaaaatgg agaatggagt gctgcacgac ggatattcat tatattaatg
       61 gatgttattg tatacaatgc agcaatatat agtagtttct tactgaagtt tcgtggagag
      121 atcccattac gaaatttaga aactttccaa cactcagcaa ttattatttc agtgattttt
      181 attgcgttga acattttgtt gggtgcatat gttttttata atcgaatgat cagtgacatc
      241 gtgtttgtca cagtcatcgg tcaggtattg atgacactag ggatcatggt agtgactttt
      301 gcgggccgct ggtttgcttt tccacgtctt gttatcttac tttcatttgt tctcggtacg
      361 cttttcttaa gtatctatcg tattctcgta tataaacttt atttacgcgt aagtcgagat
      421 aaaaaggtcg tcattattgg gttagaaaag gatgtcgcac cagcaatcca aaattttggt
      481 tcaaagaaaa acaacaaaca taaagtcgaa gcagtcattc ttgataacta ttatgcaaac
      541 atcaaaaata tgattaaaga catcgatatt gtctatcttg cttctcatat cgaagaaact
      601 gaaaaaatca aaatctatca attagttact aaaaatgaaa aaaaattgtt tttgaataca
      661 acatttgaaa acttgacatt gatcaatcca aatattatga atttcgaaga tgaaagtatt
      721 attgaagcat ctggatttag aatccaacct gaatatgaac tattcaaacg tttgtttgat
      781 atcatcgttt cacttgtttt attagttatt gcttcaccat ttatgttatt cacagcaatt
      841 ttagtcaaag tgacatcacc gggaccaatc atctataaac aagtgcggat cacaaaaaat
      901 caaaaggaat tttcaatcta taaattccgc tcgatgaccg ccacagccga agcaaaatct
      961 ggaccagttt tagctaagag caatgatgca cgagtaacgc ctgtaggtaa atttattcga
     1021 gctgtccgct ttgatgaatt accacaaatc ttcaatgtgc tgaaaggcga tatgtcgatc
     1081 gtaggaccac gtcctgaacg tcctttcttc gtcgatcagt tcaatgcaga aaacccttat
     1141 tactacttac ggcataatgt tcgtgctggt atcactgggt atgcacaagt ctatggaaaa
     1201 tatgtctctg attacaacag taaattacgt tttgatttac tttatatcaa aaaatattca
     1261 ttgatgcttg atttaaagat cttgctgcaa accatcaaga tcctatttga taaaatgtcc
     1321 tctcaaggac ttgaagaaga cgaaaatgtg atctcattgg cagaaattgc ttttccgaat
     1381 gaaaaaatct ttcgctagtt gggaggcgta aaaatgaaca atccgaaatt cagcataatc
     1441 gtaccagtat acaatgcaga agcaactatt ggtcgaacga ttgatattct aaaagaattg
     1501 gattatgaag agtacgaagt cgttttagta aatgatggat caacagatca aacacaggaa
     1561 atcattcaag aactgattga aaatgatgaa cgttttgaat tgattactac gaccaatcaa
     1621 gggcccggat tagcaagaaa cgaaggaata agacagtcaa aaggagaata tctcttattc
     1681 ttcgatgcag atgacacgcc agtaaaaacg atcttgtcag attatgatca tttgctagaa
     1741 aagagtccaa aagcggatct tgttgttagt tcgtttgttt ttcgtacaat ggacgaggga
     1801 agaatcgttt ccgaaaaaga aaacttagtt acagaatgtc actatctaac tcacgaagag
     1861 tttataaaag acatgtatca gttaatgaat gaacagttga tgtatgttgt atggaacaaa
     1921 tgctatcgta gcgatattct gaaaaataac caaattctat ttaaaactta taatagttgt
     1981 gaggatcgaa tatttaactt acattattat gaatactgtc atcaagtgat catgaaccca
     2041 aaagtagaat atatttatga atttgaaggt gggaagggga tcactaatca ataccgacct
     2101 aacaagttcg aaacatttaa agaattctat tcattagcaa atactgtaac agacgatatt
     2161 aataaagacg gtatggcggc gcttctttta aaagggacaa cttcagttat tttttctatt
     2221 tatagtacct ctgcaagaac ttcaaaagag aagaaagacg aagcaaagca gatattgagt
     2281 gatccagtga tccgagaagc caagcaaatt gctaagacgg attcttcagc aaaaaaaata
     2341 acaaagttgc tttacaatat gccagctcca ctatttttat ctgctgtaaa agttggaagc
     2401 ttcgttgaag tgaaaatgcc agggttaatg gctgctttga agcgagtata ttagttaatg
     2461 gaggaaaata taatgaaaag aattttgcat tttcagggac gaatgggttt aggtggagca
     2521 gagtctttca tgatgaattt atatcgtaaa attgatcgta caaactatca atttgatttt
     2581 ttgatttatg aagattatgc agatgttcaa gactatcatt cagagattga aagattagga
     2641 ggccgtattt ttgttgtacc taatcctaag aaaaatattt ttaaatattt aatagaagtg
     2701 aataagttac taaaaaaaga atctttttct atagttcaca atcaggttta ttttggcggg
     2761 ggaattaatt tatggttagc caaaaagaat ggaatcagac agagaattgc tcatagccat
     2821 gcaactgaag atggaaaatc tcaaaatatt gtaatgaatg tattgcgtaa atttttaacc
     2881 aaattgttgt tacaaaatgc aacagactac cttgccgtta gtcaagaagc tggtgaaagt
     2941 ctgtttcaaa accacccctt tgagatagtt cataatggta ttgatttaga gctttatagt
     3001 aaaaattcag aagctaaggt taataagaga aaagaattgg atatctcaat gagtactttt
     3061 gttgtgggaa acattggacg attagagaaa caaaaaaatc aatcttattt gttagagatt
     3121 tttttagaaa tactaaaaat gaattctgat tcttacttga ttttagtagg tgaagggtca
     3181 cttagaaata aactgaaagc caaagcagta gaattggata tagagaaaag agtaaaattt
     3241 ttaggagaaa gaaacgatat tcccgagtta ttatctgtga tggatgtttt tgtaatgcct
     3301 tctctttatg aaggtctgcc aatggttgga ttagaagcac aagcagcaaa attaaaatta
     3361 gtcttagcag atactatttc caaagataca aagttaacaa ataatgtgga ttttgtatca
     3421 ttagatgaaa caccacaaga atgggcaaaa aaagtaataa aagagccgta tgctaataaa
     3481 ataacacaag aactaaagag ttatgatgtt tcgtacacta ctgaacaaat ggagagtata
     3541 tatagtagag atcattaaaa atgttcaaga tattttagga gtgattattt ttgaaaatat
     3601 gttatttgat attggcatac aatgatattg gcaacttaaa gagattggtc aatcgattga
     3661 acgaaaatgc agtttttatt attcatatag ataaaaaaac tgatatagaa ccatttattg
     3721 aagcatttaa atcatatgat aatgttgaat ttttatgtaa taaaaaccgt gttaaaattt
     3781 attggggtgg tttttccatt gtacaagcag aaatcaattt agtaaagaga gcattacaaa
     3841 atgagaaata tttaaaatat gtattattat ctggtgctga ttatccaatc aaagataatg
     3901 agtatattta taattatttt aaaaagaata gttcagtgga gtttattcgt ggaatagatc
     3961 tagatcaaat taaacataaa gaattttatt ataaacatat agatgtatat caaaaacatg
     4021 attatcctag aattaatagg aataacacaa ctgcatttaa aatttttaga gctataatta
     4081 atcgttgtct gaggatgatt aaacttcccc caaaaattag acaccataaa tttgatttgt
     4141 atcatggttc tcaatggtgg gctttgtcga aagaatgcct aacagaatta atacaaatgt
     4201 atgaacaaaa tcaacaagac tacctgaatt ttaaaatagg tatgtttgcc ccagatgaaa
     4261 aattttttca tacacttttt tttaattcct cgttcaaaaa taaaaatgtt attggaggac
     4321 cagatttacc acttgaattg aaaaatattg aagaaactac tttacaaact tcgaaattag
     4381 caaatattca tattattgat ccttccatga acaaatggtt tgatgaaagg gatatagatc
     4441 aaataaaaga aagtgaaaaa ttatttgtaa gaaaagttaa atcggattac tctgataaac
     4501 tattaaatag aattgataaa gaaattttga aagttggaaa tatagatgaa tagaatagta
     4561 cctgttttag agaagagttt attaagtcga gatgcgtttc gagtaataaa tttaatcatt
     4621 tgtctgcttt attttatgcc tagtactttt aatgtaacta atatcccgat gaaaatagct
     4681 tttgcttggg gtggaattat agttttgtat gaggttttta taaagaaaaa tttttttaaa
     4741 atgcgttttt cttggctact gattggagca atgattagtt ttatcttaac tataatcatt
     4801 aacagagaaa attttttaat tccatctatt tataattttg gatatttgct gattactttg
     4861 atagtaattt ttcctgcaga cttttcacaa agtgaagagg aaaaaaagaa aaaaatggtg
     4921 tattttaata atgttttcat tatcataatt tttttagctg cgctaatatc tatctatcaa
     4981 tttatttttt tgatttctta tcatgtccca acaggaacgc caggattact tgcaagacaa
     5041 ggttttattg aacatcggtt atttggtgtc tatacaagtc caaatgttgg agctatgttt
     5101 ggatatactt ctattatttt aagtttaatt agtgtattaa tttcaaaaat aacaaaaacg
     5161 attcgtgttt tttatatgat gaattttatc gtacaaatat tttatattac actttcttcg
     5221 tctagaggtg cccaggtagt aatttgttct tttttagtat tatttctttt gttgtttgcc
     5281 aattcaaaat ttagaaagag cattagagaa gtactacctg taaaaatcaa atggatggta
     5341 agcatattat tagttctatt ggtatatttt tcttttggta ctaattatgc taaggatttt
     5401 ttagcaacaa ttcctgtatc gattgataga aaagtagaag ttatagagtc aaatgaatca
     5461 gataaaactc cacttccaga aaaagaagta atattacagc attctagtga taactccgaa
     5521 atttcagctg gtcgttttac gatttggaaa gctgcgctta aagttataag accaactttg
     5581 ttatttggtt atggagagac cgatttctat gggaatagcg atgcaaaatt tttgaaaaaa
     5641 gtagatcttg atactacaga tgtgaatgaa ctaaaaagag cacatggaaa catgcataat
     5701 ggatttcttc aagtacttgt atcaagtggt ataattgctt ttatatgtat ctatgctttc
     5761 tatgtgttaa atatctttag tttactcaaa acatttttta gaagtaaagt gaattatgcg
     5821 tttcttggta ttgttttaat ttttatacta tctattttta tagatgaaat ggtggaggct
     5881 catgtacttt tcaataagcg cgatgtcatt tcaattgttt tctggtatta tttgggaagc
     5941 atttcttact tgtatttaaa aaaggagaat taatatgaag acagctttca ttgcttggac
     6001 tcctttacat ttgattaata tattaaatgt ttatcaaaat ttttaccgag aatcaaaagg
     6061 agatttattt atttattctg aatttgaaaa cgctagaaga tatagtgagc gtataaaaga
     6121 attagggcta tttaatgatg ttgtttttgt gaatcaccgg aaaatcggtt cttcctttaa
     6181 acgtaaaatt aacttgttaa ctaaccataa tcaatttttc tcggatgatt tatccgttta
     6241 tgatgaaatt tttatacagg gggaaaatta tttcacaaaa atacttttct ccaatgttta
     6301 caaaaaaaat ccagatgtaa aactaaatta tatagaagat ggtttgggta cttatttgaa
     6361 gaagagtata ttttcaacaa gtaaaaacgt tcaaagagtt tttaaaatat taaataaaaa
     6421 tagcatcttc aaaaaaaaaa ttgacgatta ttttgtctat tgtccggaat tgttacttta
     6481 tgatgtaaaa aatataaaaa aaattcccaa aatagatgaa aacagtaaat tgatgaaaaa
     6541 catacaatca atctttggga tagaagaagt ttttgtcgga gataaatgta tcttttttga
     6601 tcaaccttta ttatctgatg gttatggcat agatgaaaca gatattttcg ctaaagtaaa
     6661 tagtatattt tctggaaaaa aagaaacttt aattaagctt catcctagag caaggacaaa
     6721 tcgttatggt gaaaaaaaca tattgaattc cagtttaccg tttgaagtct tgctacttga
     6781 aaatgacttc tcttcaacac ttttgattag tcctatatct acaatttctt tttcaccatc
     6841 tatgatgttt gaaaagacga tcaactctat tatgttggct aaattaattt taaatgaata
     6901 tacagcatta tctgaagata aaaaagaaac attgacaaat attgttcttt tctgtgaaca
     6961 ttataaccgt ctatcagaag aaaaaatttt actcccagaa aactgggcag aattaagaaa
     7021 gttggtagag tatgggatta tttaacacac tttccaagtc aaaattagtt aagtccagtt
     7081 tctggtatac tatagggaat ttttttatta agggaatttc attcataact attcctattt
     7141 ttgtaaatat tactactcaa gcagaatatg gtttgattaa taatttcact tcatttgtat
     7201 caattttttc gattcttgtt gggctaagcc taaattcggc aattaataat gcaagttttg
     7261 actataaaga tgacataaat gaatttatgt catcggtact ttctctagct acactttcgt
     7321 taattgtgtt cttattaata gggaacatat attttttgtt ttcaaatgct ttttttgata
     7381 tgaaccaact tgtatttaat ttgatgttat tacaaagttt tgctagtttt gtaattagtt
     7441 atatccagtc ttattttacg attaacttta accattttaa atatttgatt ttatctttta
     7501 tatctacttt tttgaatatt gcaatctctg tagctttgat gcagacatta tattttgatg
     7561 ataaatatgt tggcagagta gtcggcggaa cactgtcatt tgtgttgata ggtttagtaa
     7621 tttatttaag aataatgata aagggtgctc atttttttga taaaaaacag tggagatacg
     7681 ctttaaaaat ctctttgccg ctaatcccac attccttagc aaatatagtt ttagcacaat
     7741 tcgatagaat tatgattaat tcttatttag gtcctgctgc ggggggaata tattcctaca
     7801 ttagtaacat aggtattatt ctaagcgtaa tatggatgtc tactaataac gcctgggttc
     7861 catggttcta tggtgagatg agtaaaaata atgaaaaaaa agtgaagaaa gttagtaact
     7921 attatttagt agtctttact ttgattacga tgattgtaat ggtagtttcg attgatttag
     7981 caaaatttat ggctccgaaa gactattatt ctgggttatc tttagtggtt ccgataacct
     8041 taggctattt ctttcagttt ttatatagtt taccagttaa tgctgaattt tatgagaaaa
     8101 aaacatcgtt tattgcgatt ggtacagtag caagtgctat agttaatata ctattaaaca
     8161 tgattttcat acctaggtta ggaataattg ctgctggata cacaaccgta tttacgtatt
     8221 ttttactttt tatttttcat tataatatcg ctaaaaaaat tacgaataaa caattatttg
     8281 acacaaaaaa aatatgtatc ataataattt ttgtatcaat tttttctttg atacttcata
     8341 ttttaatcaa tcaaatgttg attcgttacg ttttgacatc attattgata attagtttag
     8401 ttatatattt tttaaagatt aagaatcgaa ttatagatga ctataattca taggaggaga
     8461 tataagtgtt taaaggaaaa acaatattag taactggcgg aactggttcc attggaagtg
     8521 aaattgttcg tcagctttta aaatatgaac caaaagctat cagaatttat agtagaggtg
     8581 aagaaaaaca attttatatg caacaagagc tctcaaatca cactaatttg agatttttaa
     8641 ttggtgatat cagagactct caaaggattg attatgcatg tcgtgatgtg gatattattt
     8701 ttcatgctgc cgcaatgaaa cacgttccag caagtgaata taatcctatg gaagctgtaa
     8761 aaacaaatgt gatgggaact caaaatgtaa tagatgcagc gatcaaaaat aatgtaaaac
     8821 attttgtagg tatcagtaca gataaagtag tgagtcctac taacaccatg ggtgcgacaa
     8881 agttattgag tgaaaaatta ataatagctg ccaatcagta taaaggaaaa acagaaacaa
     8941 tattttcttg tgtaaggttt ggaaatgtca tggggtcaag tggatctgtt attcctcttt
     9001 ttagtaaaca aataaaaaac aataaagata ttactttgac agatgttgat atgacacgat
     9061 ttatgatgtc aataccggat gctgcaagat tagttctgtc tgctgctatg aattcaaaat
     9121 ttggagaaac atatgtctta aaaatgccgg caatcaatat tttaacttta gctcaatcat
     9181 taataaaaat atataatgat acacatgatg aaaaatatag aggtgaaata aaagttgtag
     9241 gtatcaggcc aggagaaaaa ttatatgaag agctaatgac tacagacgaa attgaacgct
     9301 catatgaaaa tgataaaatg tatatcattc caccacacta tcatgctact gacgaactgt
     9361 acaaagatta tgaaaaaatt aaaatcactg catactcttc agatgcaaca gaattaatga
     9421 gtggacagga atttattaga atcgcaaaag agaataatgt cgtgacttgg taaggagttt
     9481 tatgatgaaa tcagaagtat atgtaattgc agaaattggt gtaaaccata atggaagtct
     9541 agatttagct ttagaaagta ttgataaagc taaagaatgt ggagctaacg cggttaaatt
     9601 tcaaacattt aaaacgaata agctagtttc caaaaaggct ccaatggcaa aatatcagaa
     9661 ggataatctt aaagaggaca gttctcaatt tgaaatgcta aaaaaattag aattatctca
     9721 atctgatttt attagaataa aagattattg tatacaaaat aaaattgatt ttttgtctac
     9781 tccttttgat gaagaaagtg cagactttct aaaacaaatt ggtgtacaag gatttaaaat
     9841 tggctcagga gatttaacaa atttaccttt tcttagaaaa atagatatgt atgggttgcc
     9901 agttttatta tctacaggta tggctgatat tcatgaggtc agtgaggctg tagattgttt
     9961 catagatagt ccagttacta ttttacattg tacttcaaat tatccggcta gttctgaaga
    10021 tattaattta ttggcgatta acacattaaa agaaatgttc gggatacccg ttgggtactc
    10081 cgatcattca ttgggatatg atgttggtat ttgtgctgtt gcgatgggtg ctaaggtaat
    10141 tgagaaacat tttaccttgg ataaggaact acctggtcca gatcataaag cttctttaga
    10201 tcctcaggaa tttgcagatt ttgtaaagca tattagaaac actgaaatat ttttaggtga
    10261 tggtgttaag cgagcaatgc cttctgaact tagtacaaaa gaagtatcaa gaaaaagcct
    10321 agtggtcact gagaatttaa atgtgggaga tattcttaca gagaaatctc ttacaataaa
    10381 acgtcctgga aatggaatag ctcctaagtt tttatatcaa tatattggca aaaaagttaa
    10441 aagaccaata agtgcagata gtgttctgct tgaggaagat gttgaatgaa aaaaatactt
    10501 atagtaagtg gaacacgagc tgattatgga gtatataaac ctgttgctga gaatttacta
    10561 caagataatt gggatgtatc atttgttgtt tctggaatgc atttatccca taaatatgga
    10621 tttactaaag aattgatctt agctgacgga tttagaatta gtggagaagt tcaaagtttg
    10681 tttttagaga acaataaggg aaacatggct cggtctgtgg cattagagat aaatggtttc
    10741 acaaatatat ttgaacaaac tagccctgat tttgtattat tactagggga tagaggagaa
    10801 atgttggcag ctgcgatagc ttgtttgtat cttggaatca aaacagcaca tattcacgga
    10861 ggcgaagtgt ctggtactgt agatgaatca ataagacatg ccataacgaa aatagcatct
    10921 gttcattttg ctgctacgga aaaaagcaaa gagcgtttaa taaaaatggg ggaagattct
    10981 tggagagttt ttcccgtcgg agctcctaga atagatacta ttttaaataa tagattacct
    11041 agttttagag atataaaaga aaaatatcat ctaaaatttg aaaagaaaaa atacgttttg
    11101 caagtatttc atccagttgt aaccgaacta gaaaatatag aaaaacaaat tttagctttg
    11161 atcaattcaa tggaacaaca atctcaacca attatttgca ttttacctaa tagtgatgct
    11221 ggtagcgaaa ttatcagaaa aatgtaccag aaatatttaa aaacggatat tatttatatt
    11281 acgaatttag agccggagga atacctgact atattaaaag agtgcaaatt tatgatcgga
    11341 aattcttctt ctgggataat tgaagctgca tcattcaaaa taccagtaat aaatttagga
    11401 accagacaaa atggacgaga acaatctaaa aatattataa atgcaaatct aaatgaaaat
    11461 gaaattgaaa ctgctttgaa taaaatacaa gatcctcagt ttataaaaag cttgaaaaat
    11521 gttaagaaca tctacggtga cggcaacagt tctagaagaa taacaaaaac attgaatcaa
    11581 atattgaatg atggggaaga tattaagtgg attcaaaaac aaatagctta ttaaaatata
    11641 ctagtgatcc atacattatt attggggctg gcggacacgc aaaagtcatt attgaaacct
    11701 taagattaga aaataagtta atatatggat tttttgatga taagcaaaat aaaatgcaag
    11761 atctgaaata tcttgggaaa ataaacgaat tgaatagctg ggcggatagc aaaaaaaaaa
    11821 tctataaatt tattgtagct attggtgact gtgtagtaag aaaaaagatt ataaaaaaat
    11881 tgaatatgcc aagtgagcaa tatggaatag ctgttcatcc aagtgctata gtggcaaaag
    11941 aaatttcaat tggttatgga actgttattt ttgcgaatgc tgtaattaac ccagatgctg
    12001 taattggaga gcatgctata ataaacacag gtagcattgt tgagcatgat tgtagaatta
    12061 ataactatgt tcatttatct ccaggtgtat gcttagcggg tggagtacat gtaggtgtag
    12121 gaactcaaat aggaattggt tctcaatgta tccagatgaa gaaaattgga tcttggtgta
    12181 tgataggcgc agggagcact attgttaagg atattccctc acattcctta gcttatggca
    12241 atccagctaa aattaagaaa gaaggaatta attttgaatt ctagaatttt attatcaagt
    12301 cctcatatgg gaggaacaga agaaaaatat gttgctaagg cttttaaaga taattggata
    12361 gcgccattag gtgaaaatgt ggataaattt gaagaaagta ttacaaaata tactggttct
    12421 aagggcggag cttctgcgtt aagttcaggt acagctgcca tacatcttgc cttaagactg
    12481 cttaatgttg gaaaaaacga tattgtcttt gctccttcat ttacttttat agctacagta
    12541 aatcctattt tatatcaagg ggctgtacca gtgttcattg actcagaacc taatacatgg
    12601 aatatgagcc ctgttgcact agagagcgca ttagaagaag ctgaaagaaa caaccaatta
    12661 cctaaggcaa tcatcgtagt gaatttatat ggtcaaatgg ctgattatga acgaatttta
    12721 gctattgcaa accaatttaa tgttccagtg atagaagatg cagcggaatc gttaggttct
    12781 acttataagg gaatttcgtc aggcttattt gggacaattg ggatctattc atttaacggt
    12841 aataagatca tcacaacctc aggtggagga gctctagtgt ctagtgataa aaaatatgtt
    12901 gagcattcaa gatttttagc aacacaagca agagatcaag caccgtatta tcaacatagc
    12961 gaaataggtt ataattaccg tctaagcaat atttctgccg gtatcggacg tggacaaatg
    13021 gaagtattga atgatagagt agctaaacga agagaaattt tcaatcgata taaggaagct
    13081 ttttctggaa ttgatagaat tgaaatgatg ccagaagtgg atggcatggt gccaaatcgt
    13141 tggttgtcta ctttaacgat caatgattat aattctattg atcaagtagt taacgtaata
    13201 aataaactaa atgaaaaaaa cattgaaaca agagctttgt ggaaaccact acatttgcaa
    13261 ccagtatttc aaggggtaaa aatgtattac catgataata atcttagtgt gtcagaaaag
    13321 ttatttaata gcggcttatg cttaccttct ggaagtaata tgacagatag tgaacaagaa
    13381 tttgttattg atgagtttaa aaaaatattc aagtaggtgt gatattttat gaacatagga
    13441 attattggtt taggttccat ggggaaaaga agacttagac tcattcaaga acactttaat
    13501 gatattttac tatgtggtgt tgatactaat gaggcgagac gaaaggaagt tgaaaaggaa
    13561 tttggaatac caacttataa tagtctaaca gaggcaaaaa atttgtttga aataaattca
    13621 gtttttgttt gtacatcccc tataacccat gaatttatta taaaagaggc tttaaattta
    13681 gattgtaata tctttacgga aatcaattta ttaaatgaat attatgatga aataatcgaa
    13741 gtagctaaaa agaaagatag attactttat ctatcttcta catttttgaa gagaaaagaa
    13801 attcaatata ttaagtctaa agtgacgcat aataaaaaaa tttcttatca ataccatgta
    13861 ggacagtatt tacccgactg gcatccttgg gaagattatc gcaatttttt tgtttcaaac
    13921 aaaaaaacta atgggtgtag agaaatattc gctattgaat taccttggat tatagataca
    13981 tttgggaaag ttaaatcgtt tactgtaatg acccagaaat tatccaatct tgatattgat
    14041 tattcggaca gtttcactct tattattgag catgaaactg gtatagttgg aactttaagt
    14101 gtagatgttg tttcaagagt agctaaaaga aatttaacta taattggtga aaagatttta
    14161 atagaatggg aaggtaaccc ggattctcta ttttcatgga atgaagaaac ttctagtatg
    14221 acagatattc aattgtacga tgaggttatg catgataata attattcaca tactattatt
    14281 gaagatgcat atttagagga gattaaagaa tttttcacgc ttttggaaaa gaaaatggaa
    14341 ccccaatata cttttgaaaa agataagtat attattaact taattaacga cattgaggta
    14401 aattaatgat gaaagtaatt ttttttgggt tagggtcaat tggaaagaga catctaaaaa
    14461 atctaataag ctatggaaaa aagaattcta ttaattttga tataacagct tatagtagca
    14521 gtggaaaaaa agagtttgaa gaaataacgt atattcaaaa tagagacgat ttggatacac
    14581 attatgatat agcttttatt acaaatccga cttttaagca tctggaaaca ctaaatgtaa
    14641 ttgttgaaaa agttgattac atatttttag aaaaacctgc tttttctgag agtattgatc
    14701 ttactcaata taattatgat tacaaaaata tttatgttgc tgctccactg aggtataaaa
    14761 atatcatgga agttgttcgt aatagtattc aaagtaaaaa agtatattct gtaagagcta
    14821 tttgttctac ttatcttcct gattggagaa aaggtactga ttatagaaat aattattctg
    14881 cctttaaatc tatgggggga ggagtagaat tagactgtat acatgaattg gattatatta
    14941 taaacctatt tggtttccct aaatcagtaa aaaaacagtt tggtaaatat tcgaatcttg
    15001 aaattaacag taatgattta gcaacatata tattgagata cgatgataaa attatagaaa
    15061 ttcatttaga ttattttgga agagttccta caagaaaatt tcaattgttt actttagatg
    15121 aatgtatcaa tgttgactta ttaaataata aaataagttt tgaagaaaac attgttaaag
    15181 aaatgcctga atctgctaat gatatgtatg agaaggagtt gaaatatttc tttgaaaacg
    15241 tagtaacagg caaagaaaac tggaatgatt tatatcatgc aaacgaagta ttgaaaatag
    15301 ctgaggagaa ataaatggaa attttattta ctatttgtgg tagagctggg tctaaggggt
    15361 ttaaaaataa aaatttgaaa tatttggcag gaaagcccct agtccatttc gctttagcaa
    15421 tgatagatat ctatcaacaa aaacatcctg aacataattg cacgacttgt ttgaatacgg
    15481 acagtaatga gttagtagaa ttgacgacta agttaaatcc gtctgtgaaa attgtagaac
    15541 gtaaacctga attagctaca gatactgtag ggaaaattga agtgatacgt gattcattct
    15601 tacaactaga aagagaagat aatatatttg atttaattat agatttagat ttgacttcac
    15661 ctttacgtga agtttctaat cttgaagaat taatagatga acatctaaaa aatttagata
    15721 aagacgtcta cttttcagtt gtttctgcaa gacgtaatcc ctattttaat atggtaaaaa
    15781 gaattgaaaa tgaagttact atagttaata aatcaagata cacatctagg caacagacac
    15841 ctgaagtttt tgaaatgaat gcctcaatgt attcttttaa acctgaattt ctaaaaaaaa
    15901 gtaattatat ttttgatggg caatgtggga taataaaaat gagagattat ctaattttag
    15961 atattgatag tgaagaagat tttaaatggt tagaattttt gtttcctaaa tttttagaag
    16021 attcttcgga gcttcaagat atctataatt atttatatcg gaggtaaaag gatgagctgt
    16081 tatcttatca ccggtggggc tggcttcatt ggttctacct tagccaatca tttaggagaa
    16141 gaacatgtgg taatcgtcgt cgatgactta tcaatgggaa aagtagaaaa tcttgatatg
    16201 acgaaaaata tcacttttat tgagggagat gtcgctgaga aatccttgat ggaagagatc
    16261 atgaaagcta ataaatttga ttatatcttt catttagcag cagttgctag tgtggcagat
    16321 tcagttgccc gaccagtaga aacacatcgt gtgaattttg aaagtgtatt aatgatttta
    16381 gaattgatcc gcaagtatca acctgattta aaacggatcg tgtttagttc ttcagcggct
    16441 gtttatgggg atgaaccgac tttaccaaaa aaagaagagt ccgtgattcg cccattgacg
    16501 ccttatgcgg ttgataaatt cgctgcagaa caatatgtgc tagattattg tcatttatat
    16561 gatgtacccg gtagcgcagt tcgttttttc aatgtctatg gtccaaatca aaatccgaat
    16621 tctccataca gtggtgtgat ttctattctc gtagatcgct ataagaaaca aatcgtagga
    16681 gaagcaactt catttacatt atttggtgat ggaagccagt ctagagactt tgtttatata
    16741 gatgatgtaa tccaagcatt acttttagtt gcgaatgagg aagctgcact ggggaaacaa
    16801 ttcaatgttg gaacgggtaa agcaaccaca cttttggaat tgattcatgc aatcaatgaa
    16861 attctcggtg tagaattgac acttgaatac aaagaagagc gttcgggtga tatccatgac
    16921 tctctagcag atattactaa gatccagtca attggctatc aaccgaaata tggtatttta
    16981 agtggaatga ctaattattt gaaaactgaa atcaattaaa acatactaag ataagattag
    17041 agggtaaatt caggctcttt gtcaataagg actgatgagt tttgtaaaat caaatctggg
    17101 atagaa
//
LOCUS       DBBGSZ010000049        17006 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.051, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000049 DBBGSZ010000000
VERSION     DBBGSZ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17006
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.051"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..125)
                     /locus_tag="ACIZE5_002331"
     CDS             complement(<1..125)
                     /locus_tag="ACIZE5_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HGC6109444.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(229..540)
                     /locus_tag="ACIZE5_002332"
     CDS             complement(229..540)
                     /locus_tag="ACIZE5_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGC6109445.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(542..739)
                     /locus_tag="ACIZE5_002333"
     CDS             complement(542..739)
                     /locus_tag="ACIZE5_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HGC6109446.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1133..2860)
                     /locus_tag="ACIZE5_002334"
     CDS             complement(1133..2860)
                     /locus_tag="ACIZE5_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HGC6109447.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2853..4046)
                     /locus_tag="ACIZE5_002335"
     CDS             complement(2853..4046)
                     /locus_tag="ACIZE5_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HGC6109448.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4233..4877)
                     /locus_tag="ACIZE5_002336"
     CDS             complement(4233..4877)
                     /locus_tag="ACIZE5_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6109449.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4971..5105)
                     /locus_tag="ACIZE5_002337"
     CDS             complement(4971..5105)
                     /locus_tag="ACIZE5_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HGC6109450.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5107..7239)
                     /gene="feoB"
                     /locus_tag="ACIZE5_002338"
     CDS             complement(5107..7239)
                     /gene="feoB"
                     /locus_tag="ACIZE5_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HGC6109451.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7236..7709)
                     /locus_tag="ACIZE5_002339"
     CDS             complement(7236..7709)
                     /locus_tag="ACIZE5_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HGC6109452.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8110..8334
                     /gene="nrdH"
                     /locus_tag="ACIZE5_002340"
     CDS             8110..8334
                     /gene="nrdH"
                     /locus_tag="ACIZE5_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HGC6109453.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8493..10652
                     /gene="nrdE"
                     /locus_tag="ACIZE5_002341"
     CDS             8493..10652
                     /gene="nrdE"
                     /locus_tag="ACIZE5_002341"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HGC6109454.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10702..11667
                     /gene="nrdF"
                     /locus_tag="ACIZE5_002342"
     CDS             10702..11667
                     /gene="nrdF"
                     /locus_tag="ACIZE5_002342"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HGC6109455.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11756..12895)
                     /locus_tag="ACIZE5_002343"
     CDS             complement(11756..12895)
                     /locus_tag="ACIZE5_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGC6109456.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13204..13917)
                     /locus_tag="ACIZE5_002344"
     CDS             complement(13204..13917)
                     /locus_tag="ACIZE5_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HGC6109457.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14171..14872)
                     /gene="nagB"
                     /locus_tag="ACIZE5_002345"
     CDS             complement(14171..14872)
                     /gene="nagB"
                     /locus_tag="ACIZE5_002345"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HGC6109458.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15106..16638
                     /locus_tag="ACIZE5_002346"
     CDS             15106..16638
                     /locus_tag="ACIZE5_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGC6109459.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16829..>17006)
                     /locus_tag="ACIZE5_002347"
     CDS             complement(16829..>17006)
                     /locus_tag="ACIZE5_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6109460.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5278 a         3495 c         2910 g         5323 t
ORIGIN      
        1 gaaaaaacac attccactaa atttgatgcc ggttttcctt gaggttttgt tccagcacct
       61 cctttaattt ttttaagctc ttgatctgaa cattgtttag catttagtct atttttttct
      121 tccattacga ttccccctac aaactataaa tacttttatg tcactgattc aatataccta
      181 tttttctaat caaaaaattt tgagacatat ttaatattat aagtatcatt aaaattgaga
      241 tttatctcca taatctgctc gatataaacc atttattcca gcagttcttc caatttcact
      301 caaatttctt attaattcct cttgatattc agtgaatctt attttattag tataagcagt
      361 aaaatataga taattcacca atctatttat taaaggactg ggatctaatt catatttttg
      421 tttttctaat tttaaatata ccttttgtaa aacctcaaga atatcagaat atttaggatc
      481 tttacttata gatatatcat tatataattc atgaacaatt tgcttagcat tttttttcat
      541 tttagcactt ccctggaatt gctccaccta aaaaaccacc tatagacatt cctgcaatac
      601 aagtagttgc cttggcccaa tcgaccgtac atttattttt agtgcaatac actccatttc
      661 cataatattt tccactatga gtggtacccc catagataag ttgtgtctct ttaatagaca
      721 aaatttttaa atgtttcata atctaatcac ccctaaatta atgtttttag actattattc
      781 taacattcat taaatttcaa aaaacaattc cttcttgaaa cgtagcaaaa taattcctga
      841 ataagaattt aatcactttt aagtatataa actatgtata ttctttaata ttttttgaga
      901 atgcacttcg tacataataa actttaatca cattagtctt tcatacctac gatcgatctc
      961 tttgactcgc acccataaat tcataatagt ttgtcggcgt ctttgaacgt ttcgaagatg
     1021 agctacgcat tctctttttt tatagacaaa aaagatagag acgaacatgg agcttccaaa
     1081 tttggatatt tgatccaatt ttggaagctc catttatttc gtgtctgtct ttttattttt
     1141 tccagctttc gactaattct tggttctctt tgatccagtc ttttgctgct tgctgtggat
     1201 cttttccatt gttgatttcc aacataactt tttccatatc tttttctgac caatggaaat
     1261 tgtctaatac tttgtaagct tctggctggt cttctttcaa tccttttcga accatcgtat
     1321 ggatctgctc ttcgcttccc attccgtttt caggatcttc taagtatttc agatcatatt
     1381 tggcaaacat ccaatgaggt gtccatcctg taactacaat tggttcgtgt tttttgatcg
     1441 cttgacctag tgcaacggtc attgctcctg aagaagatgt ctctactttc cagtctttca
     1501 agttgtcata tttttggatc gtgttttcag cagccgtaac tacaccagct cctggctcga
     1561 ttcctatgat tttcttacct gcctgatcgg ttaactcatc gatcgaattt acatccatgt
     1621 aggctggcac tgctaaacca acttttgctc ctgtcaaatt ggcacctagg tcttcgactt
     1681 gatctttata ttgtgcatat tgtgaaccat gagttttagg tagccaagct gaaaccatgg
     1741 catctgactc gccatttgaa acagatttcc acatgattga attatctaat ggcgtcatcg
     1801 ttacatcata gcccatttgt ttcaatactt caccgactac atttgttgaa gcaacttctg
     1861 tatcccattc aacataagat aagttgatac gttttgtttc tttggcagat gaaaaactcc
     1921 ctataccaat cgcacctaag atcactacta ctacagcacc aatgatcagt ccttgacgtt
     1981 ttttactttt ctgtgttgtt gctcctgcag cttttttatt gtttggctgg ttcaaatgct
     2041 gtgtaaaacg gtcaatgatg attgctaaga taactaatgc aaccccgttg acaaatccat
     2101 tcccgacttg tgctctttgc aatgctgata atacgccgcg tcctaagccg ggtgcaccga
     2161 tcatagaggc aataacgacc attgaaagtg acagcattgt tgtttgattg atccctgcca
     2221 tgatcgtact tttagctaaa ggcaattcta gtttgaatag tttttgacga cttgtgctcc
     2281 cgaatgaatc agaagcttct actaattctt taggaacttg tcgaatccct aaattcgtaa
     2341 aacgaacggt tggtggcaga gcaaagatga ctgaggcaaa tacccctgga accatcccga
     2401 taccgaaaaa tgcaactgct ggaatcaaat aaacgaatcc tggcattgtc tgcataaagt
     2461 caaggatcgg tttgataata ctttgggctt tactgctttt tgccatcaag atccctaatg
     2521 gtaccccaat gatgatcgag atcacactag ataaaagaac aagtgtgaca gtattcatca
     2581 aatcattcca tagaccttgg ttataaataa accatagacc gattaatgtg aacaacgtaa
     2641 gtcctggacg tttcttagaa ataaagaaag ctgctaccgt caataacaag ataaacaaag
     2701 gagctggaat cactaacagt aaatttgtaa tccccgacat cactgcctgt ccaatcgttt
     2761 gtaaaaatga aaataggcca gaaaaagttg tcgtaaacca ttctgtgata ttttctaccc
     2821 agtttgccac tggtaattga tagttcaata gattattcat gttcactcac ctcgcttgtt
     2881 tctgctaatg cttcaatcac actacctcgg atgacgacac cttttaattt tccatcctct
     2941 acaactgcaa gtggagtcgg tgagtcataa ataatattga aaatatcact taccaccatg
     3001 tctttcccaa tcaccgtcac attttcatct aggaagtcga tcaatggacg tttttgcttc
     3061 ctagcttcta acgcttgatc tgcagtgatg atccctttca ggtgtctctt tctgtcaaca
     3121 gccatcagca tgctgacttc ttcattacgc atccttgtca atgcaacgtt tggtccatca
     3181 gattcgatat tcgtcgtcaa tgcaggtacc atgatgtttt gagccgtaag cactttggaa
     3241 cgatcgactt cttccacaaa ttcacgtaca taatcatttg ctggattggt caatatttct
     3301 tcacctgttc cgatctgcat gatttcgccg tctttcatca aggcgattct gtccccaatc
     3361 cgtaaagctt cattcaaatc atgggtaatg aaaataatcg ttttttgaac attggcttgc
     3421 aggtccagta attcgtcttg catttctcgc cggatcagcg gatcaagagc cgagaacgct
     3481 tcgtccatca gcaagatctc aggatcattt gctaaagctc tggctaggcc aacccgttgt
     3541 tgcatcccac cagataactg actaggatat tggtctttaa atgaaagcaa actagaattt
     3601 tctaatgctt tttctgcttt ttcttgtcgt tcttctttag gtacaccacg gacttctaac
     3661 ccgtattctg tattttccaa gatcgttcga tgtggaaaca gaccgaagtt ttggaaaacc
     3721 atattgattt tatgacgacg gacttctcgc aattcttctt tgcttaactt cgatacatct
     3781 tctccatcaa tatagatact gcccgaagtt ggctcaatca gacgattcaa tagacggatc
     3841 aatgtggatt tcccactccc ggaaagcccc atgatcacga agatttctcc ttcttttacg
     3901 tcaaaattca cgtcatacac accaaccgtt gcaccggttt tctttaaaat ctccgttttc
     3961 ggctggtgat cattcatcat atctaaagcg gcttgtgtct ttttaccaaa tatctttgtt
     4021 aaatgtttta cttctacttt taccaaacaa attctccttt tttatgtaaa ttcatttttc
     4081 tttctgaaaa aagtgaccac actatgttaa catcatgtag tcactttgtc aaaaatgaaa
     4141 gaaatttgct tgtccaaact gaaaaaaact tggctaaatc tttgtaaata aaaggtttag
     4201 ccaagttaat atttttttaa tatttcacac aatcattctg caagctgatg ctccgggtaa
     4261 aaaaagtttg tcatacgctg tagtgtatat tcatttccaa taaaatgaac gatgtcccct
     4321 gccgtaaatt tagcataggg gccaggtgaa acaagcagtt cttcattatg agaaattgcg
     4381 ataactgtgg cgccagtcgc ctgccagata ttcaactcgc taattgaacg gtccagatgc
     4441 attgcttttt ctgataaaga taattcaaac ggaagtaaag gattcatctt atgtattcgc
     4501 ttcgtttgat tgaccagctg atccaataat tgagaaaaat gattcagctc atcttgttgc
     4561 ttctccacac ttgccatgat ttctgctttt gtatcttgga tggattgtac atcttgatat
     4621 tgcaatagga aatcttttgc tttttccttc gaagcaacaa atgccccact tccatgccgt
     4681 acttccatga ttccaagatc taccagcaca ttgatagcct tgcgggtagt ctcaggagaa
     4741 gcattgtacg tactggcaag tgttgagcgg gcatggatct tctcacccac tttatatcgg
     4801 ttttcaacga tacgttcggc taaatcaaca gcaatctgct ggtagcgcgg gcggacgatt
     4861 tttttctttc cagacatttt ctttcctctt tcttttttta ctttccctca tcttactatg
     4921 ctctagcaaa ataagcaaaa aaggggagaa tagcctcttg caacgactga tcatcgcttg
     4981 atctgttcct tttttactgg gcaagctgtt tgacagtcat cacaattctt accggatttt
     5041 aaacgagtat agacaattgc gcctgcactt ccaaagatta acacacttaa taagaatgtc
     5101 gccatcctat tcctctcctt ctaatgacaa tatagtataa aactggttct tggattttgg
     5161 ctgacggaac aaaacataaa cgagtcctat catcagtaaa atagcaagat acgtccctaa
     5221 cgctacctgt ccaccctcca ataagtgtcc caactgataa atcacaaaac taactaaata
     5281 agctaaaccg cattgatagc ctatggcgat ccaagtccat ttcttggcat tcatttcccg
     5341 atggatagcc ccaattgccg caaaacaagg cgcacaaagt aaattgaagg ctaacaatga
     5401 ataagctgct gcgggagtat atgtgtgttg tagcacttgc cagatttctc tgccattttc
     5461 ggatacttcc gcatgaccaa acaaaatacc aaatgtgcca ataatatttt ctttagcgac
     5521 caatcctgta atcgctgcga ctgttccttg ccagtttccc caaccaagcg gctgaaaaac
     5581 aactgccagg attcgcccga aaaaggctaa gatactttgg tcttcagaaa caggttgagc
     5641 ataaaaatta taagaagagc tgaaccagat cacgatacta gaaacaaaga taatcgttcc
     5701 tgctttttta acaaaagact tgctgcggtc ataggtttgt cttaggaccg ctgaccattg
     5761 aggaaaatga tatgcgggca attccatgat aaaaggagct gtatctccag caaacaaacg
     5821 tgtttttttc aagctgattc cagagaaaat aattgcagtc ataccaagaa aataggcaga
     5881 aggagctacc caagattgat gaggaaaaaa ggcccctgct actaaggcaa taatcggcaa
     5941 ctttgcagaa caaggcatga aggttgtgac catgatcgtc aaacgacgat cttgctcgtt
     6001 ttcaatcgtg cgactggcca tgacgcctgg cactccacat cctgtagcaa tcagcatagg
     6061 aatgaaggat tttcctgaaa gaccgaattt cctgaaaagt cgatccatga caaaagcgat
     6121 cctcgccata tatccgcagt cttccagaaa gctcaagcat aaaaacaata taatcaattg
     6181 cggtagaaat cctaacactg ctcccacgcc tgcgatgatg ccgttcaaga tcagctcctg
     6241 catccatccc gctacttgcc attcagctaa caatctgcca acatgttctg gtaaccatgt
     6301 accaaacaat gtgtcattga tccaatctgt ccccattgtt cctactgttt gaatagccag
     6361 ataatagatc agccacatca caaatgcgaa gatcggcaag gctaaccaac gattcgttgc
     6421 aatctgatcg attttgtcac tcatcgataa ttggaaagaa tcatttgaca caacacagag
     6481 tgtacatagt tgggtaataa attcataacg ttcattgacc agaatcgtct cactatcgtc
     6541 gtccaatagt ttctctgtta actggatcag ttgctcgatc tctttttgct gagaaactgc
     6601 tatctcgtaa tcctctctta ccttctgatc tcgttcaaaa tatttcattg cataccagcg
     6661 tttcttgccg ctttgttctc ctagtacatc ttcaatttca tgtaaagctg cttctaaacg
     6721 tggatcatat gtacagggaa caggaataga aggccgcttt tttgcagact cctgaatctt
     6781 ttcgattagt ttttcgattc cttgcttttt caatacgctg attggtaaaa ctggtacacc
     6841 aagaccatag gaaagctttt ctagattgat tttttttcct tcttttttga tgacatccat
     6901 catattcaga ccaatgatca taggaatgtc taaatccaat aactgcgtag ttaaataaag
     6961 atttcgttct aaattggtag catcaataat gttgatgatc agttcaggct gttcctgaac
     7021 caaataatct cttgcaatca cttcttctgg tgtataagga gacaaagaat agatgccggg
     7081 taggtcctga atatgaatgt tcggattttt tttcaacgat ccttcttttt tttctactgt
     7141 tacgcccggc caattcccta catattgatt cgaaccagtc aagagattga acaagctagt
     7201 tttcccgctg tttggatttc cgactaacgc gatattcatt ctttttcctc cctttgtatc
     7261 aagattagtt cggcctctga ctttcgtaac gtcagttcat accctcgcac tgtcagttcg
     7321 attggatctc ccagaggggc tagttttcgg ataactattt ttacatttcg cgtcaatccc
     7381 atatccatta accgtcgctt cactgcgcct tgtccgtgga ttgctacgac gatcccagtc
     7441 tctcctgctt ttaattgatc aagagaagtc cagctttcag aggaagcagt ctttttattg
     7501 acaaagattt gacctagtat ttcccgactt actgccactc gatgactttt taccagtaaa
     7561 atggcattgt tgcctgataa attgacgacg acgattttac ttccggcaac gatcccgata
     7621 ttttgcaaat ggcgttttgt tttttcttct gtttcgattc gttcgacttg ataaacgaaa
     7681 ttctgctttg cctgcgctaa ggtctgcata ttgattcctc tcttgtgaaa taaatcatgt
     7741 attaaaatca ttcattatat gttctaattt tcttacgtgt tacgcaaata aatgagaatc
     7801 attctcacat agaatactct cggtaattga gaatgtcaat tatacttgtg atattatgag
     7861 cgaatcttta gtattgatag ataaaaatga gaaaaaaata tttcttcata gttttccaca
     7921 attttttctc tattaaattt gctattttcc cacacgatac ttgttttcag ctcttttttc
     7981 aaaaacacaa aacttagtat tccacagttt ccacaacaca atatgtagtg tttgttgttt
     8041 gactttttta ctaagagttt tatactatct attatagata ataagaatgt gttagaggag
     8101 gcactcacca tgaacgtaaa aatcttttct aaaaataatt gtatgcaatg taagatggtc
     8161 aaacggtttt taacagaaaa tcaaattgct tttgaagaag tcaatatcga tgaacagcct
     8221 gaagcagtag actggttgaa agcacaagga ttccaaagtg ttcctgtcat tacttctgat
     8281 gcagaaacag ttatcggatt ccgtcctgat cagttgcgta aacttgccag ctaacatgac
     8341 taaaagaatc aaaacgtgat acatggattt gaagggcttg agacagcacc agtttttgtc
     8401 gcaaacttcc aaatcctttt ttaaagctta aaaacaatgc aatgatttgc aatcaagcat
     8461 catcaaatac gaaatgaagg ttgggcgtac gtatgagtct taaaaattta caagatgtca
     8521 gttatttcaa gctgaataat gaaatcaatc ggccagtcaa tggtcaaatc cctttgaata
     8581 aggataaaga agctttagtt gccttttttg aggaaaatgt caaaccaaat acgatgactt
     8641 ttccatctat tatggaaaaa atcaattact tgatcgatca agaatatata gaagcagaat
     8701 tcattcaatt gtattcacca tcatttattg aaaagctata tcaatttttg gacgagcaac
     8761 atttttcttt caaatctttt atggctgctt acaaatttta ttctcaatat gcgttgaaaa
     8821 ccaacgacgg ttccgcttat ctggaaactt atgaagatcg agtagccttc aatgcgcttt
     8881 actttgcgaa cggggatgaa gaattagcac ttgctcttgc agacgaaatg atccatcaac
     8941 gatatcagcc agctacacct tctttcttga atgctggacg taaacgtcgg ggcgaattgg
     9001 tgtcttgttt cttgactcaa gtcactgacg atatgaactc tatcgggcgc tcaatcaact
     9061 ctgctttgca attgtcccgt attggtggcg gcgtagggat tactttatca aatcttcgtg
     9121 aagccggcgc tcctatcaaa ggatatgagg gtgctgcaag tggtgtcgtt ccagtcatga
     9181 aattattcga agatagtttc agctattcta atcaattagg tcagcgtcaa ggagctggcg
     9241 tggtttattt gaacgttttc catccagaca ttattgcttt cctttcagca aaaaaagaaa
     9301 atgcagatga aaagattcgc gtaaaaactc tttctcttgg cgtgatcgta cctgataaat
     9361 tttatgaatt gacacgtaaa aacgaagata tgtatttatt tagtccatat agtgtcgaaa
     9421 aagaatatgg tgtcccattc tcttatgtaa atattacagc tgagtatgat catctagttg
     9481 caaatccaaa cattcgcaaa caaaaaatca aagcgcgtga tcttgaaaat gaaatctcaa
     9541 aattacaaca agaatctggc tatccttacg taatcaatat tgatacagcg aaccgcgaga
     9601 atccaatcga tggcaagatc atcatgagta atttatgttc agagatttta caagttcaaa
     9661 cgccttctgt gattaacggc aaacaggaat atgaagtatt aggaacagat atctcatgta
     9721 acttaggctc gacaaatatc gtgaatttga tgcaaagccc taactttggt caatctgtgc
     9781 gtacgatgac tcgtgcattg acatttatta cagatgcatc tgatatcgat gtcgtaccac
     9841 cgatccaaaa cggaaataag ctgaatcata cgattggatt aggtgccatg ggcttacaca
     9901 cttatcttgc aaaagaacaa atggaatatg gctcagagga ttcattagac tttacaaata
     9961 tttacttcat gctgttgaat tattggacac ttgttgaaag caacaatatc gctcgtgaaa
    10021 gaaaacaagt tttccataat tttgaaaaat cagcttatgc tgacggcact tatttcgaaa
    10081 aatacgtaac tggagaattc cagccaaaat cagaaaaagt caaagcattg tttgaaggca
    10141 tttttatccc aactgctgaa gattggaatg ctttgaaaca agcagtaatg aaagatggac
    10201 tgtatcatca aaatcgcttg gcagtagcac caaatggctc aatttcatat atcaacgata
    10261 cgagtgcaag tattcatcct atcactcgca tgatcgaaga acgccaagag aagaaaatcg
    10321 gtaaaattta ttacccagcg ccttatctat ccaatgagac gattccgtat tacacttctg
    10381 cttatgatat ggacatgcgt aaagtaatcg atgtttatgc aacggcacaa caacacgtcg
    10441 atcaaggcat gagtttgact ttattcatgc gttctgaaat cccagaaggc atttatgaat
    10501 ggaagacaac aacgaagcaa acgacacgtg atttgaatat tttaagacat tacgctttcc
    10561 acaaaggaat caaatccatt tattacgtac gtacctttac tgatgatgca gaagaaatcg
    10621 gaagcaatca atgtgaaagc tgcgtgatct aatatcatag atagattcgc ttattcatat
    10681 tttaattaaa ggagcattct catgtcagaa acatattatg aagcaataaa ctggaatgaa
    10741 attgaagata tcattgataa atccacttgg gagaagctga cagagcaatt ttggctagat
    10801 acacgtatcc cactttcaaa tgacctagat gattggcgta cattgtctca attggaaaaa
    10861 gatacagtag gacatgtatt tggcggtttg acactgctag atactgtcca atctgaaagt
    10921 ggcatggatc agttgcgtaa agatgtccgc actccccatg aagaagccgt tttgaacaat
    10981 attcaattca tggaatccgt tcatgccaaa agttattctt ctatttttag tacactgaat
    11041 acgaaaaaag aaatcgaaga aatttttgac tggacaaata cgaatcctta tctgcaaaaa
    11101 aaagctgagc gtatcaatga aatctacaaa cacggtacac cgctagaaaa gaaaattgcc
    11161 agcgtctttt tagaaacatt cttgttctat tcaggttttt atactcctct ttattattta
    11221 ggaaacaaca aattggctaa cgtagcagag atcatcaaac taatcatccg agatgaatct
    11281 gtacatggaa cctacatcgg ttacaaattc caattaggat tcaacgagtt acctgaagca
    11341 gaacaagaaa cgttaaaaga ctggatgtac aatcttcttt atgagcttta cgaaaacgaa
    11401 gaacgttata cagaagaatt atacgatcca atcggctgga cagaagaagt caagacattc
    11461 ctacgctata atgccaacaa agcattgatg aacctaggga tggatccact ctttccagat
    11521 actgccaatg atgtcaaccc aatcgtaatg aacgggattt caacaggcac aagcaaccat
    11581 gacttcttct cacaagtcgg aaacggctat ttgttaggtc atgtagaagc gatgaaagac
    11641 gacgattatt tgattggatt ggaataagga tttattttaa ttcaaaaatt tttcgaaaaa
    11701 taaaaagagt ttagcgtaca gatattttaa atgtacactg aactcttttt tatgcttatt
    11761 cacttgtttc ttccagcact tttggactgt ctaacttttc cgaaacatgt tccattcttc
    11821 tcaataaata gattttccgg atatttaata ttatcgtctt aatcactgca tagacaggta
    11881 tgcaaatcag catgcctaat attcctgcga cacttcctgc tccaatcaat accaagatga
    11941 tcgtcaaagg atggatattc attgatttcc caaataacaa cggcttgatc aaatttccat
    12001 ctaattgttg gatcactaaa atcgacaacg ccatatacaa agcttgaaat ggagagataa
    12061 acaaaccgac aatgattgct ggtaccgctc caataaaagg gccgacatac gggataatat
    12121 tcgtgattcc gcaaatgacc gcaagcaaca agctataagg ctgatcgaat attctcattg
    12181 ccaaaaagct cattacacca ataatcaaag catctaagat cgtactgctg atataggcag
    12241 ataatgtttc gtttaattct tttaccgttt ggcgtaactc tttacgaatc gctttcggaa
    12301 agaagtgaga caacgcatca ataaatttgt gcccatcctt gaacataaat agcaaaataa
    12361 atggaacggt aaataacaaa ataaaaaatt gcatcataaa tgaaatgatt tttgagacac
    12421 ttgcagataa actgactaat atgatattga acaaattact aagagataaa tttgctgatg
    12481 ctaattgttc ttccaaattg aaatttttaa actcttcccg ctgcgccaat tcatttaacc
    12541 atttgcttgt ttcatctgca tacattggca agctctgggt caattgaatt gtctgttcca
    12601 ttaactgagg cactacattc atgacagtta aaacaactaa aatgattacg accaaaaacg
    12661 tcaataaaaa accgaacact ctcgggatcc gatgcttttc gagaaaaaca acgattggat
    12721 cgaacatata atagataaaa ccagcaacaa gcaatggtaa aaaaattgcc gaaagcattt
    12781 tcaatattgg actaaaaata ttcggcattt gtaaaataaa gtacacgccg atgatcgtga
    12841 gtactagctc cactgtccag aaaaataatt ttgattgttt aaaacgtgat tgcatacatc
    12901 tcctccaagg tcctttgata cttctattct atcatttaac aaagagttac gcgctgagat
    12961 tttcatttgc ttaaaaaaaa caaaaaaaat aaacatattt taatgagtag acgagtactt
    13021 aaacaaaaac acggtttgga gtagtgacaa aaattatact gcagtccctt tttccaaata
    13081 aacggtgttc aaaagcttgc atcttcgtaa taagcccagc caaacgaaaa atataaggaa
    13141 ctatttttat ttggctgggc ttattacttg atgtaggaca tctattttac aacctcagat
    13201 catttattgc gcaatactga ctaaatgcaa ctttgtgata tttttgtgta cggacaactc
    13261 ctcgatcaca tcggcataag tgagcccttt tggaagatca atcgtataga tatttttgta
    13321 cactcggtag tcatcaacga attttacgtc aaaattcaca tcttcgatta cgatattttt
    13381 ctcttcaaaa taatcggtaa gaaaatcttt ggtttctttt ctatggataa attggatttc
    13441 taacttttta gtcgtaggta catggatcac gcgtttcact actgtgagtg caatagcaat
    13501 cccgataaaa ctgatgatcg caatggaata gtaacccatg ccgatggcga tccctaatcc
    13561 agcaattgcc cataaagaag cggcagtcgt aagtcccgtc accgattgtt tcgtgacgat
    13621 gatcgttccc gcgcctaaga aaccgacacc actcaccact tgagcaatca gccttgcttc
    13681 atctgaacga atcgttccag caagctgtgg atactctaaa gcatctctta atgcaccact
    13741 agcgatctca acttggatca atgcaatgat acatgctccc atacaaacta aaatatgcgt
    13801 acgcatacct gctggacgat ttttatattg tcgttcaaaa ccgattgctc cgccaaatag
    13861 catagcgatc cctaaacgta aaataatctc tggaattgtc aataccatat cattcatcta
    13921 aacaccctcc agtccaatat atcatgtctg aaaggagcag acaaaaaaag tgcaattttt
    13981 acctcttacg aaaaaaggac tgtgacaaaa tttttgtcat agtccttttt atgaataaac
    14041 ggtgttcaat cagctgaccc tcggtattac tcaacaaacg gcaaaatatg gggagctatt
    14101 tttcctttgt cttctctaat actcaggtca aaacgctgat ttcacaacct ctttagccta
    14161 ctattgaaaa ttacaactta cttgctgctt cttcatcgat gatcacaaca acattgtcgt
    14221 gattttgcaa tacacttgct ggcaaatgat tcgttacagg tccttcaatc atccctttga
    14281 ttgcatcagc tttgctttcg ccaaatgcca tcaagacgat ttctttactt ttcataattg
    14341 aaccgattcc cattgaaaca gcttttgttg gtacatcttc tgctttatcg aagaatcgtt
    14401 tgtttgcatt gattgttgat tctgttaagt caactactga agtcgttccg tcaaatgaag
    14461 caccaggttc attgaaaccg atatgtccat tttgcccgat tcctaagatt tggatatcga
    14521 ttggatgtgc atcgatgatt tgatcatact ttttgcatgc tgcttccaga tcttctgctt
    14581 ttccatctgg tacaaacgtt tctttgaatg gttttttatc aaataattgg acatccatga
    14641 aatgacggta gctttgttca tctgaaccgc ctagtccaac gtactcatct aagtttacag
    14701 aagtcatttc actgaaatcc aaatcgcttg aagtcatttc tttatataaa gtaactggtg
    14761 tgcttcctgt tgccaatcct aatacttttg cacctttgtt cataccttct ttgatgattt
    14821 caaatgcttt ttttccgcct tcttcagcgt tttttacacg aatgatttcc atagtgattg
    14881 ctcctttata ttttggtata gcccaattat agcattcttt ttttcttttt acaataatta
    14941 gtatagacca aattgcattt ttttcatttt cttgacaata aataggaatc cgtgttaggt
    15001 ttcataagat ggttcaatca aacaatccat gttgcatgaa aaccaagcaa gtgattcact
    15061 gtggacgctt tatgtctgca gtttttttat gaaaaaggag ttattatgag tatactgaca
    15121 ttaaacaaca ttacccagca atttggcgac aaaatcctct atgaaggtgt cgatctgcaa
    15181 ttaaatgctg gcgaacatct tgggctgatt ggacaaaacg gagccggtaa aagtacattg
    15241 attaaaatca tcactggtga gatcttacca gatgacggac agatccattg gcaaaaaaat
    15301 attcacaaag gttacctcga tcaatatgtg gaagtcgatg aaacattaac aatcgaagaa
    15361 tttctaaaaa ctgcgtacgc aaaagaatac gaaaaggaag aaaaaattgc ttttctttac
    15421 caaacatata gcgagacctt cgatgattcc ttgctggaaa aagctgggaa actccaaacg
    15481 gaattagacc aaggagtgtt ttatcaaatc gacaccttag ttgctgagat gagcagcggg
    15541 ttggggatcg atgtcttagg tttagattca ctgttgaaaa atctaagtgg tggacaacgt
    15601 tcaaaggtga ttttagcaaa actactttta gaaaacccag atgttctgat cttagatgaa
    15661 ccaaccaatc acttagatga tcagcatatc caatggctga cgcagtttct tcaggatttt
    15721 gacggtgcgt atatcgtgat ttcccatgac caagaatttc ttgatcagat caccacccat
    15781 atcgcagaca tcgagtttgg aaagattact aagtatactg gccatctaaa acaagcattg
    15841 aaacaaaagg aacaaaatcg cgaaagctat ttgcgccaat atcatgctca acaaaaacaa
    15901 atcgaaaaga ccgaagctta tattcgaaaa tacaaagccg gttcccgatc aacgatggca
    15961 aaaagccgac aaaaacaatt agataaaatc gaacggctga cgcctccagc ttcagcaagt
    16021 aaagctgtct ttgattttcc attctcgcct attgtcacga cattagcagt ggaaacaact
    16081 gatttagtca tcggatatga tcgaccgcta cttgcaccca tcaatttgac catccgcttt
    16141 ggtgaaaata ttgccattcg aggcttcaac gggattggaa aatctacttt attaaaaaca
    16201 ctgatcggtg agattgaaaa aataagtggc gatttccact tcccagataa cacaaaaatc
    16261 aattactttt cacaagatct gtactgggaa aatccattag aaacaccact acaatattta
    16321 agcagtcaat ttccaaaagc gactatcaaa gaattacgtc gccaactagc taaagcaggg
    16381 ttagttaatc aattagcaag tgaacctctc actacattaa gtggtgggga acaaactaag
    16441 gtgaaacttg cacagttgac aatgaaccaa ggtaatttac tgattctcga tgaaccgacg
    16501 aaccatatcg atcaagaaac gaaagaaagc ttacaagacg ggatacagaa atttccagga
    16561 acagtaatca tcgtctctca tgaacaagaa ttttatcaag atcttgtgca acgagtcatt
    16621 gagattgaac caaaataaac gtttgattga atagttgaaa aaaaggagct gtgacaaaag
    16681 ttttgtcaca actccttctt ctgaataaat ggtggccaat tagctgacct tcggtattag
    16741 ctcaaaaaac ggcaaaatat gaggagctat ttttatttgg ctattcttat tacttgatgc
    16801 agaacagctt ttcacaacct cttttcgtct attttttatt ttcgagattt ctctttcctt
    16861 taaaaacaac tgtttgaaag aagaacgcac atccttgaaa aacaagcccg ctaaccgtta
    16921 cacctaacca gccatactgc tgccacattg tcgtccctag caatgaacca gccgcacctc
    16981 caataaagta cataaacata aataca
//
LOCUS       DBBGSZ010000050        16578 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.052, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000050 DBBGSZ010000000
VERSION     DBBGSZ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16578
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.052"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            64..990
                     /locus_tag="ACIZE5_002348"
     CDS             64..990
                     /locus_tag="ACIZE5_002348"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HGC6109461.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            1172..2065
                     /locus_tag="ACIZE5_002349"
     CDS             1172..2065
                     /locus_tag="ACIZE5_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HGC6109462.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            2199..2324
                     /locus_tag="ACIZE5_002350"
     CDS             2199..2324
                     /locus_tag="ACIZE5_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGC6109463.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(2458..3090)
                     /locus_tag="ACIZE5_002351"
     CDS             complement(2458..3090)
                     /locus_tag="ACIZE5_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109464.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(3238..3780)
                     /locus_tag="ACIZE5_002352"
     CDS             complement(3238..3780)
                     /locus_tag="ACIZE5_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HGC6109465.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            3915..4304
                     /locus_tag="ACIZE5_002353"
     CDS             3915..4304
                     /locus_tag="ACIZE5_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109466.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            4308..5072
                     /locus_tag="ACIZE5_002354"
     CDS             4308..5072
                     /locus_tag="ACIZE5_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HGC6109467.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            5201..6148
                     /locus_tag="ACIZE5_002355"
     CDS             5201..6148
                     /locus_tag="ACIZE5_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6109468.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            6278..7018
                     /locus_tag="ACIZE5_002356"
     CDS             6278..7018
                     /locus_tag="ACIZE5_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109469.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(7309..7977)
                     /locus_tag="ACIZE5_002357"
     CDS             complement(7309..7977)
                     /locus_tag="ACIZE5_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGC6109470.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            8111..8398
                     /locus_tag="ACIZE5_002358"
     CDS             8111..8398
                     /locus_tag="ACIZE5_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109471.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            8814..10352
                     /locus_tag="ACIZE5_002359"
     CDS             8814..10352
                     /locus_tag="ACIZE5_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HGC6109472.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            10349..11314
                     /locus_tag="ACIZE5_002360"
     CDS             10349..11314
                     /locus_tag="ACIZE5_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6109473.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            11301..12623
                     /locus_tag="ACIZE5_002361"
     CDS             11301..12623
                     /locus_tag="ACIZE5_002361"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGC6109474.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      12686..12790
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            12864..13607
                     /locus_tag="ACIZE5_002362"
     CDS             12864..13607
                     /locus_tag="ACIZE5_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6109475.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            13622..14614
                     /locus_tag="ACIZE5_002363"
     CDS             13622..14614
                     /locus_tag="ACIZE5_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6109476.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            14626..15363
                     /locus_tag="ACIZE5_002364"
     CDS             14626..15363
                     /locus_tag="ACIZE5_002364"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6109477.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            15353..16075
                     /locus_tag="ACIZE5_002365"
     CDS             15353..16075
                     /locus_tag="ACIZE5_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HGC6109478.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(16159..>16578)
                     /locus_tag="ACIZE5_002366"
     CDS             complement(16159..>16578)
                     /locus_tag="ACIZE5_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HGC6109479.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         5616 a         2794 c         3382 g         4786 t
ORIGIN      
        1 gtattgcttc tttccgtttt tttgctatta ttaaatagga gaaatcacaa aggagcgaat
       61 gacatgtcaa aaattttagt ttttggtcac caaaatccag atacagatgc aatcggggca
      121 gccattgcgt tttcacactt gcaaaatgaa ttaggtaaag aaacagaagc agttgctcta
      181 ggtacaccta atgaagaaac acaatacgca ttagaccact ttcagctatc tgcaccacga
      241 gtagtagagt cagctaaagc agaaaatgca gatgtcatgc ttgtggatca taatgaattc
      301 caacaaagta tttcagatat cagcgaagta aatattttag ctgtagtaga ccaccatcgt
      361 attgcaaact ttgaaacagc taatccattg tactatcgtg cagaaccagt tggatgtaca
      421 agtacgatta ttttaaaact atataaagaa aaccaagtaa caattcctaa agaaatcgca
      481 ggaatcatgc tctcagctat catttcagat acattgttgt tcaaatcacc aacatgtacg
      541 cctgaagatg aagcagctgc aaaagaactt gcagcaatcg ctgaagtcga tctaaacact
      601 tatggacttg aaatgttgaa agcaggaaca aatctaagtg ataaatcagc tgcggttctt
      661 cttgatttgg atgcaaaaag tttcccaatg ggcagttcca acgttcgtat cgctcaagtc
      721 aatacagtgg accttaatga agtgatggat cgacaagcag agctagaagc agcaatggaa
      781 gatgaaatga aagcaaatgg ctacgatctg ttcgtattag ttgtcacaaa catcttagac
      841 agtgattcag aattacttgt tgctggtaaa ggaaaagaaa aagtagaaga agctttccaa
      901 acaactttga ccaacaaccg tgctttgctt aaaggtgtcg tttcacgtaa aaaacaagtc
      961 gtacctcaat tgacggctgt atttagctaa tcaaatggta gtatgaagca ttcaaaatga
     1021 atggataagc gattgatata aaaagaaaca tagaacatac taaaggccga agaaatggag
     1081 gagaataaca gtcaattatg actcttgttc ttcctccttt ttacgtaaaa gccttttaag
     1141 taaaataaaa cggatagaaa agagaacata tatgaactat tattcaaaaa ataaggaaaa
     1201 cttttatcaa aaactgaccg atgatccgct tttttcttca ttgaccgatt atctatatga
     1261 acatcgagaa caagaaacga ttctaagaga attgaaaaaa gaattttcgc aaaataaatt
     1321 ttcccatttt cttgatttat tgatcgatgc aggattaatc aagagggaag aacgaagata
     1381 tcatttgaac tttccaatat ttgatcctaa agattacttg caacaagcca cttcggctgc
     1441 tgaaaccata gctgaacaat tgaagagact ctctgttgat gaacaaaaat tagcgatggg
     1501 agaagttatt tgggcgtatt gtttcgaaga tgaacggaaa gaagcgtatt tttatggagt
     1561 aagaaacagc cgagagacag aattgctgag gacaactgca ggaaatgaga agtaccgttt
     1621 tatcacactt tcctctatag aacacttccc gcttactttg gctaattact tttttgtaca
     1681 gaagaatcag cttcctgtaa cgaaggcatt caaagaatta gccgaactta ttggagacgt
     1741 aaatgaatcg tacttttttg atcaaataga agttatcgtt gacaggatac gtaagaataa
     1801 atataaaaat cgccggccta gtattttcca tcagtctcta cttgtgacga atactataaa
     1861 ggaagaagaa tcattcacat tagaattacc tattgtcgaa aaaaacaatt ttgagattga
     1921 attaccaaca ttggatcctt cattgacaat ggaggaaatg gcctttctta aacgacaaat
     1981 cttttctgag ctgagcaaga aatttatacc gcatgcattt tcttatatca aagaatatgg
     2041 aacagtttta gtgagtaaaa cctaagagag cagtaagcaa aaattatact gactcttgca
     2101 ggaggagcct ttctcttcct ttatggttaa aagaattatt tgagtatttt gcctatctac
     2161 cacctattag attcactaca tggtctggaa acaaaggaat gcaaaaaaat ggtgagaaat
     2221 gtggaatgac aaaggaagta gtgataagaa aagttagatt tttaaataat caatattatg
     2281 attcagtcaa gtatggcatt ttatgggaag aactagctga ttagattagg aagtccattt
     2341 gataatccag aatcactaag aaacgaatgg cgagtcatta ataatttatc caatcttggg
     2401 ttattctttt agattgaagt gtttaaaact aaaaaagcat ttatgaagtc gtaatagtca
     2461 ggcttcaaaa tgctttttat tttgtttgtt ttttctttgc cacataaata cacctagact
     2521 gacgatgaag agcatatcca acagatttcc tgcgacttgg atcgtcgaag ggttggtcag
     2581 tggcattaaa gcaaggacaa aaaaggaaaa caagctgtaa ataaaacagg tgacaggaac
     2641 taatcgaaag aagagcggac atttcaattg gctaaaaatg agtgaaaaaa taaaataagt
     2701 aaaaatggat aaaatcacga ctaaaccatt catgataaag aagaaaagcg tattgtgatt
     2761 aaacgaataa aaaagaattg ctaaaaaaga aaacgtttta aatgcaatca atacgcttga
     2821 agcttcgttt aacgtaccag gatgtcgatg aaaaaaatag gcaccgaaat aaacagaaaa
     2881 cagtaagccg caaagagaag acaaaatcaa aaaaaacgga ttttcttcgg cttctgtgat
     2941 atcagaatga tccaaaagca accagcctaa tgcactagaa ggcgcatgtg aggtcttaag
     3001 gtatgaataa catagaaaaa ataagatcgt caaagttgca aaaaaagagc ctaaatgtaa
     3061 aaaattagtg gttctacgtt gaatttccat aatatctcca aattaaattg ataagtatat
     3121 aaagtataat aacaaattga tgagtatatg tcgatgtttt ttaatcaaaa taataaataa
     3181 aaactgtcta acatttaaaa tttaatttag atattagaca gtttttaagt ttgtgagtta
     3241 ttttccttgt cgttttctca cttttttagt ccagaaacca cctgaaatat attttggctc
     3301 ataagaaatg ataaaagcac gctcttcgat ttctttgatc aggcgataca gttcacgttc
     3361 gctttttcta ggagaaagta tttcgagaac tagccgctca ccttccagcc ccattgcaga
     3421 agtctgtgtc acaccataac cgtgttctct cagtataccc ggcaaacttt tatcttctgc
     3481 gctatttgct ggcaaaatcg ttgtgaccat gatgtatcct aatgccaatt tgtcttcaat
     3541 caaaattccg acactgatac ctactgcgta acctaacgca tagacaaata aattcagtgg
     3601 attatctaaa cgatctaaaa caagggataa gccgacgata taaatcgtga tctcgaccat
     3661 actgacaagt ggagcaatca gtcgatagcc tttcattgtc aacatgaaac gtaacgtgtt
     3721 cagagtgata taagcaaaat taatgaggaa gatcatcccc aacatttttg gatcaatcat
     3781 ttgtaaaact cctttcattt atataacaac aatatcaaaa aaaatcgtaa gtgaagaaaa
     3841 attgaaactt tatacataca aaaaaatgat aaaatgatta taatagaatt ataaagatag
     3901 gttaggtgat taaaatgaaa acggtcaatc gtgtgttttg tgccagccac gtgctaagtc
     3961 tccttctcag tatatactta ggtgtctatt cgattcaaca gccaattgag gtagagaaca
     4021 ttgtttttca gatgtcgctg acagatggtt taattttaag cgtttttttc tttttgatac
     4081 tgtttattgg taatattttc ggtagcgttg ccagtttttt gaatttttct atttatccac
     4141 tcctttcgct agcattagga gtggtgggac tttgttctct gtgcttattt cccgagccat
     4201 tcagtcctgc atttatatta tttggtacac tgaacctgtt ccagacaact gttggagcat
     4261 ggttgctatg gcgatcagga aatttaatga aaataggtga gtaacaattg aatccaatta
     4321 tattgaaacg ttctgtccat catattccag tgttagaagt tgttctgaaa gaattaagag
     4381 aggaacgtat tcccgttgtc atctattatc acggatggca gacaagtaag gagttagttt
     4441 tgacgcaagg aagaaaaatt gcgcagcagg gcattcgtgt gatcctgcca gatgcgatga
     4501 atcatgggga gcgcaaacag ccggtttctt ctattccatc ctatacattt tgggatagta
     4561 tctacggaaa tctgtttgaa tttgacacac ttatcaagca tttagaaaaa agaggtcttc
     4621 tacatgatca gcttgcagtt ggcggggttt cgatgggggg aatgacaaca tgcgccttgt
     4681 tggctaaaca tcctcatata gtagcgggcg tgtgtttgat gggttcccct gcacctttgg
     4741 aatatggaaa agaaatcgta aggcgcgcat cggaatataa ttatgtcgta ccaaaagact
     4801 attttgattt gatttcatgg gttaagagct atgatttgtc attgcagccg gaaaagttag
     4861 ctggacgtcc tctgttcttt tggcatggac aagctgacga aaaaatccct tatatacaaa
     4921 cggaacgatt tgtagaaaaa aatcggcata agtcttacgg aaaagaaatt gtttttcgtt
     4981 cctcaaaaac acagcgacat atggtacaaa taccactaat ggaagaagct tccacttttt
     5041 tagcaaaaaa tttgataaaa aagtataaat aattgaaacg gaaaatcact catgacgata
     5101 gaggattttc cgttttttat tttgggctat aataaactct gttaggaaaa tttggtataa
     5161 ttgatagtaa gaatgacaac atgttagaaa ggaagagagc atgcccactt tagcagatgt
     5221 tgcaaaacgt gccaatgttt caaaaatgac ggtctctcga gtcatcaatc atccggaaca
     5281 ggtgactgac gaattgaaag agttagtttt ctcagcaatg gctgaactgg attaccgtcc
     5341 aaatattgct gcaaaagcac ttgtcacgaa tcggtcgcag atcatcaaat tatttatact
     5401 ggaagaaatc gacacaactg agccctatta catgaatttg ctgatgggaa tcgctaaacg
     5461 gatcggtaaa gcgcattatt ctctccaatt agttacaaat gatgccttcg acgtcggttc
     5521 ttgtgatgga tacatcatca caggtgtcag aaaaaaagac ttcgattgga tcgaccgttt
     5581 ggaaaaacca gttgtcttgt ttggggaaaa ttctgaagga tatgattatg tagacagcga
     5641 taatgaatat ggtacagcaa aagcaacgca atatgcctta gaaagagatt atcaaacgat
     5701 tatttatatc ggtatcgaag tggacgagcc ttttgaaatt tcaagggaaa ctggttattt
     5761 atctgtgatg aaggaagttg atcttcctag taaaatcttg cggtttccaa atcattcgac
     5821 agaagtagaa agatatatga cagaaaactg ggcagatttt acagataaaa cttgttttgt
     5881 atgtagttca gatcggctag cactaggagc agtaagaggg attataaatg ctggaggaca
     5941 cttgcccgaa gaatttggtg tgattggatt tgatggggta tttttagacc aaatcagttc
     6001 acctaaattg acaacgatca agcaagatat tatacgtatg ggtgaagtat gtggagaaat
     6061 gttgttaaaa aaaatagaag aaaaaggggc gagtcaaggt tatcgtcgtt tttttcctga
     6121 actagttatc agagagacaa cgaattaagt cttattacta tatatatatt tatgaaattc
     6181 atcgctattt tcttaaaata atcagcgcat tgctactgaa aacaatgaat ctgtgctatt
     6241 attgagaaaa gttccatttt tgagaaggat ggtttgaatg aaagaaatca gacgaaaaca
     6301 tttccgtttt cctgcgtacg atgatgagtt aggcgtaaaa ttaaccaacg acaagaagcg
     6361 agtattattt gacggacaag aagatctttt gactgaacag aatcagtccc cgtttgaaca
     6421 gatgaaagaa tttcatttca cgaacacgaa caccgagaaa atccgtcgca agcgtcgtgc
     6481 aacaaatgga ttgaagtcag ctccgcgtaa ggaaaatttg gaaaagcata aaggaaaatt
     6541 accggattat accggccatt accaatcaga aatcacatcg acaggacgaa aaaaactttt
     6601 tggtgattcc tctcgttctg tcagacaaag tgaaacaagg acagagtcca agcatactac
     6661 acgaaacgca tctgttgaca cgaaggtgcg ggagcgttct tattttgttc ctaaatatgt
     6721 acccgcatcg attatcccag accctagaga aagcaaaatt tctgaggatc atttaatcga
     6781 atcgatgaaa aaaacggatg actcttatct gttgttcgat acagaaccga cgccgtatca
     6841 agaaaaaaga aatggtgagc cgtctgtacg aacattcaat cgaacaaaaa cgttagagga
     6901 aacaaagcag tcagaagaaa aaaaatcgaa aaaaagccat ggtatcttag aacgctcatt
     6961 acaaggattg atcgatgatc aaggaaactc tttgggagaa aatagctatt ttaaataagt
     7021 gatatacaaa tttatattcg gctacagttg gaaaggaaac gctgcggcgt ttccttattt
     7081 tatactctat ccgaaagttt atatcgtatc ctcaaatttt tttgagttta agcgaatttt
     7141 ttctcccaat aagtaagaaa ataatggcaa aataaaaaaa caaactattt tcgcagatcg
     7201 tttgcaaaaa tagtttattt ttttataaag aagattttac tgaataatat cattttagtt
     7261 tacataatga tatttctgta aattaaataa agtagtgaaa aataagaatc agtgctctaa
     7321 ctgttcaaga ggatcaagtg gttcaaatgt ttctgtagtc tgttttgctt ccaattgggg
     7381 caaaacagat ccaatttcca gatacttcac tttattcaat gtataagata gaatagaaca
     7441 gctaagtaat gtatacagaa aatgtgtgag atccaaataa agcaaggaga caactaaaat
     7501 accaaaagta atcaagaaaa gacttttgcc aatcttaata tgaaaatatt tttcaatggc
     7561 ttgataaatg atatctgttc cgcctgtgct tccgccgaat cgaaagacga gaccgcaacc
     7621 aatgccagaa agaatacctg tcatcaaact attgatcagt agactatcta cagcaaaatg
     7681 tatatgaagg ctctcccata aatgtaaaaa gaaaactagc gcaaatgttc cgacgatcgt
     7741 ccggagaaaa gcgtgttttc caaaaagaaa caatgagata agcaataaag gtaaattaaa
     7801 aagcagtgaa gtgacagaag gagcgaatcc aaaaagatta tgcaaaagca aagcaatacc
     7861 agtaacccca ccatctgcca gcttagatgg aatattgatt cctgtcacag ctaatccgta
     7921 gattcctgcg cctaaaatga ttccgcacaa ttctgtaaat aaatttaatt ttttcatttc
     7981 tagcctcttt tcttttgaaa attttcagca acttctttat tatactgact tatactctta
     8041 cttcaagagg aaaatgaaaa aaaattattt ttggctgttt ctttttattt atcaaataag
     8101 gagtggaaaa atgcgagcag cagacttatt gacaattctt acaaaatcac ccaaaaaaac
     8161 agagtatcaa ggagtttttt tggctcaaga acaaaaactg gtgcctgtga caatggtcca
     8221 gataaataaa gcaaatcaat ttatcttttt atttgaacac ggcaaagcac cacttgctat
     8281 gaaagacatc tttctttttt tgatgaagaa ccgtgagaaa gctgtttatt atcagtcaaa
     8341 agaagaactc attcctcttt atggagtgaa agagatagaa aataaagtgg tgatataagt
     8401 aaaaataaga aaacaagacg tttatgatgt caaaacaacc attttttaca tttttggcaa
     8461 aaaagtgtca tgatacagta taatattcgt tgaacaggcc aataaaggtg ttctccccca
     8521 cgagatttct actttattgg ctgtttcttt ttattaaaat aaaagttgtg tgtgtaaaaa
     8581 agatatagct gattccaagt gacaatttcg tatagatttt tatggtattc gtagtgaaaa
     8641 aacgagaacc aaaaagttga tccgactttg ttgcttggat tctttttttg tcagcatatt
     8701 tagaggtatt tttttctttt ttttgttcgt gctgtaaggt taaggcaaga caagttagtt
     8761 gggaaaaagg aaagaaatgt ttatacttaa agaataacag aaaggaaggt cgcatgaata
     8821 attttataca aacattaagt gaaagaaaag gcgagttgct ggaagctgca tttcaacatc
     8881 tgtccatttc tctcatttct ttgctgattg cagcactgat tgctattcct ttagcgattt
     8941 gggcagccaa tcataaaaaa atggcagaag tcttattgca gatcacgggt gtgctccaaa
     9001 cgattccttc acttgcctta ttaggtttac ttatcccatt tgtagggatc ggaactgttc
     9061 cagcattgat tgcacttgtt atttacgctt tgcttccgat tttccaaaac acgtatattg
     9121 gtctagctga aattgacccg tctattgaag aagcagcggt agcatttggt atgtccagaa
     9181 tgagacgctt gctgaaagta gagcttccca tcgcattacc tgtcattatc tcaggtatcc
     9241 gaactgcctt agttttaatc atcggtacgg ctactttggc agcattgatc ggagcaggtg
     9301 gattagggac atttattttg ttaggtattg accgaaatac acctgttttg acattgattg
     9361 gtgcgatcag ttctgccttg cttgcaatta tattcagcgg actgattcgc tggttgcagc
     9421 ataagaaacc tcgatattcc atcattactt tagcagcagt ggtgtgttta tttggcggcg
     9481 tttctttata tcagtctgcc ttgtttaaaa atgaaaccat cacgattgct ggaaaattag
     9541 gagcggaacc tgaaatcctg atccaaatgt ataaagaatt gattgaagac aacacaaaaa
     9601 cagaagttga attaaaaccg aattttggca agacgagttt tttgttcaat gcactggatc
     9661 aaggtcaaat cgatatctat cctgagttca caggtactgt cctagaaagc ttggtgaagg
     9721 tacctgaagc aatgaaaagt gctgatttga caaaagaaaa aacatatgac gaagcagaag
     9781 aattattgaa taagcaattc gatatgacat tattaaaacc aatggcttac caaaatacgt
     9841 atgccttggc agtcaagaga tcttttgcga acgaacatca acttaaaaag atttccgatt
     9901 tggcagctat ctctgatcag atcaaagcgg gattcacact ggaatttatt gatcgttcag
     9961 atggatataa aggaatccaa gaagcatatg gcttgaattt ttcaagtgta caaagcatgg
    10021 agccaagttt gcgttaccaa gcaatcaata atggagatgt caatattgtg gatgcctatt
    10081 ccacagatag ccagctcaag gagtacgatc tagtgactct agaagatgat cgagggttat
    10141 tcccagctta tcaaggcgca ccgctgatga aaaaagattt tgctaaagaa catcctgaaa
    10201 tcgttaaagc actgaataaa ttaagcggaa aaataacaga ggatcaaatg attgatatga
    10261 attaccaagt caatgtcgaa aagaaaaagc cgacagaagt agcacgaatc ttcctgaaaa
    10321 atgaaggatt agtaaaggag gaagatcagt gactaaatta atcgagttca aacatgtgca
    10381 aaaaaagtat gatggaaagt atgtcatcga tgacctaaat ctggcaatca aaaaaggaga
    10441 aatctttgtt ttggttggtc cttccggtag tggaaaaaca actactttga aaatgatcaa
    10501 tggattatct aaaccatcag caggagacat ctacttcaaa ggaaaatcgt taaatgaata
    10561 taatctgcag aaaatgcggt ggaatatggg atatgtgctg cagcaaatcg ctttgttccc
    10621 gaccatgaca gtcaagcaaa atattgaagt catccctgaa atgttaggtt gggaaaagca
    10681 gaaaagagca gaccgtgtag atgaacttct tcaaaaagtt ggcttatctc ctgatattta
    10741 tcgagatcgt atgcctagag agttgtctgg aggagaacag caacggatcg ggatcatccg
    10801 agctattgct gcaagcccag atgtgatttt gatggacgag ccatttagcg cattagatcc
    10861 gatttcaaga aactcattac aagaattggt tttgtcctta cacgaagaat tgggcacgac
    10921 catcgttttc gttacgcaca atatggaaga agcaatcaag ctaggtgatc gtattgcatt
    10981 tatgaaggat ggagaaatta tccaatgtga cacaccagag cagttattga tgaatcctaa
    11041 aaacgactac gttcggcatt tctttgatga accgaaacag acgaaagagt ggcgagtaga
    11101 agatttagtc gtcaatggat atttcttaaa tgaaatacca gaaaatgctc gtcaacaagt
    11161 ttgctttgat acgcctatga aagaagtata ttcgcttctt tcggtgtatc caagcattgt
    11221 gatagtagaa aagcaaagaa gtattgggtc gctgacaagt aaagaaatct ttgctttttt
    11281 aagtcgagag gaggaaggaa atgaaaacat atgatgcaat catcatcggt tcaggtgtga
    11341 gcggcttaag tgctgcttat ggattgaaag aagcaggtaa aacagtacta gtggtcgaag
    11401 aagatctatg gggcgggact tgtcctaacc gtggatgtga tcctaaaaaa gtcttgttaa
    11461 gtgcagtaga ggcacgtaat cgggtaaaac aattgagtgg aaaaggtttt aacgagatcc
    11521 caactgccaa ctgggaagaa cttcaaaaat tcaaacgaac atttacggat ccagtcccag
    11581 aaagccgaaa aaaacaatta gcagaagctg aaatcgatca tctttcagga accgctcgtt
    11641 ttttggatga ttcatctatt gaagtcaacg aagaagtctt ccatgcggat tacttagttt
    11701 tggcaaccgg gcaaagacct acgatcttac cagtggaggg aaaggaatac ttgaaaacta
    11761 gtgcagactt tttatcattg cctgtactgc ctaaagaaat catttttatc ggtggtggtt
    11821 atattgcttt tgagctagct acgattgcca atgctgcagg gagcaaagta accattgtcc
    11881 atcataatca acggccatta aaagaatttg aggcgtcttt ggtagaggaa gccgtccatc
    11941 aaatggaagc atctggcatt cagtttgctt ttggtgttga aacccaaaag atcatttcag
    12001 aaggtactcg ctatcgttta gtcggaaaag agacggaatt agtagcagat atgatttttt
    12061 gtgcgactgg gagacagccg aatacagaat ctttagcact tgagcaagcg aatatcgtct
    12121 ttgataaaca cggaattgca gtcaatgatt atctgcaaac gagcaatcca aaaatttttg
    12181 cgtgtggaga tattgtttca aggaaaaccc caaaattgac accagtcgcc acttttgaag
    12241 gaaattatgt agctaagcgg ataacggatg caacaagcga acctatcaaa tatccgatta
    12301 tacctacgat cgtctacgcc agtcctaaac ttgctgaagt aggagttaca aaaagtcacg
    12361 cctcttcgtc agatcaagtg gtagagatgg atcttaccag ttggttcacc tatcatcgtg
    12421 tcaatgaacc agttgctaag gctgaattga cctttgacca gcaaaattat ttgattggtg
    12481 ctgcagtgat tagcgagcaa gcagacgaat tgatcgatga tttgacactc gtcatcaatc
    12541 aaaaattgac taaaaaagag ttggatagct atatcatggg gtatccgaca ttggcaagtg
    12601 atctctccta tttattgaaa taatcagcat gataactaaa gcgcttgttg ctttttcctt
    12661 cttgtgctac actttaaaaa atgaatacct gtttctgggg atgtcgtaga cgacatgaga
    12721 gtaagttgtg aacttagacc cattgaacct gtcagttaat actggtgaag ggagaaacat
    12781 agcagacgct tgaagcgggt tactatgtcg tgcccatttc aagcgttttt tgttattcat
    12841 attagaagaa aggaggtaac aaaatgaaga aaaatcttta tccagcagtc agtatggcat
    12901 tcattttaat tatttggcag attgttgtca tagtttggaa aatacctgcc tttattttac
    12961 ccggacctgc tgctgtattt tctgcattag cggcagatgc acaagtatta ctttcccatt
    13021 ctgtcacgac attaaatgaa gcagtgcttg gtttggtaat agctagcgtt ctttctttta
    13081 ttactgcctt ggcaatggat tattggaagt ttttagaaat gtctttttat ccgttactag
    13141 tgatttcaca aatgttgcca atcatggtgt tagggccatt acttacccta tggtttggtt
    13201 tcggtatgct tccaaaagtg atccttgttg tcttgataag ctattttccg atcgtagttt
    13261 ctttttcgga tacattgagg aaagtatcaa aagagcaaat catctttttg aaaacgatgg
    13321 gggcagatac agggaagatt tatcgaatat ataaaatacc agcgggttta tccggcttct
    13381 tttccggttt aaaagtggct gctacttatt gtgtcagcgg agcagtcgtt ggagaatggc
    13441 taagcgctca agcaggctta gggtattaca tgatacgcgt aaaaaacagc taccagatcg
    13501 ataaagtttt tgctgcgatc atttgtgtca ttctattgag tttattgctg aatggcgctt
    13561 gttcattatt gaaaaaaggg tattatcgta tgctttatat tttttaagag aaggggatca
    13621 aatgaaaaaa ttatggcttt tattaccgct actgttgctt ttatccgctt gtggcactgc
    13681 aaaagaaaca agtagcaaac aagaaataaa ggatttgaaa aaagtgacac ttgttttgga
    13741 ttatgtaccg aatactaatc atactggcat ctacctagca aaagaaaaag gctattataa
    13801 agaggctggt ttaaatgtcc aaatcatcga accaggagat aattcgacaa gtattggtct
    13861 agtaggtgcg gacaaagcac aatttggtgt aagttatcaa gaagatgtca cttatgctca
    13921 cgcagatgga cagaatatac cagtcaaagc aattgctaca gtgatcaaac ataatacttc
    13981 tggattcgcc accctatcag acagtaacat ccattcacca aaagattttg aaggaaaaac
    14041 atatgcaggt tggcaaagtc caagtgaaga agctgtctta aaagctgtga tggaaaaaga
    14101 cggcggggac ttttcaaaac tgacaatggt aggaagcaat ggagaagggc cagaaagctt
    14161 aggaaaatcc tcagatatcc aatggtactt tgaaggttgg gatatgatca aagcaaaaga
    14221 agcgggtatt gaactaaact atatcccatt gaaagaatta gatgaacggt tagattacta
    14281 tactccggta attattacga atgatcaact gatcaaaagt gatccagaat tggtacagtc
    14341 ttttatggat gccacgaaaa aaggctatca ggaagctatt aaggatccaa atgacagtgc
    14401 taaactgttg caaaaatatg caaaagaaaa tgatcggacg tttttagaag aatcacaagc
    14461 attcttgtca aaaaattata cggatgatcc tgagaattgg ggattgatgg aagaaaaagt
    14521 ttggcgcaat tatacagctt ttatgcagga aaacggattg atcaagcaag atgtaccttc
    14581 gcaagaacta ttcactaatc agtttataaa ataggagtga tagatatgtc aatccaaatc
    14641 agccacttga atgtagtcat tgaaaacctg aaaatattag aagacatcca tttcactatc
    14701 cctaaagata cctttacatc gattgtcgcg ccaagcggag ccggtaagtc aacattgctg
    14761 aaaactttaa caggagtcca gcctatgact tctggaacga tcaaagtaga cgatcaaaaa
    14821 gtaactggtc tccatacagc atttagttat atgccgcaag aagatatgtt acttccttgg
    14881 ctgagcgtct atcaaaacgt tacgttatat caaaaaatca atcatctaac aatcaatgaa
    14941 gaacaagtaa gggattatct ggatatcttt gggttaaacg gctatgaaca ttttttgccg
    15001 gaacaattat ctggcgggat gaagcagcga acggccttgt tacgaacaat catgaatcct
    15061 tcttcttact tgcttcttga tgaaccattt ggagcgttag atgctatgac cagagggcag
    15121 atgcaagact ggatgttgaa gctgcctaaa aaagcaaagc ggactacttt acttgtgacg
    15181 catgatatcg aagaagcaat ttatttatca gacaggattc ttgtgctttc cgcccgtccg
    15241 gcacatgtga ttgctgagat tcaagtgcct gaaaaacgac ggtcacgtga atggctactg
    15301 cagcaatcag agttgaagca aacgatttat cagttattgg caggtgaatt agatgttaag
    15361 tgatgctcat tgtcatttag atgggagtca gagtttagca ctccttcagc aggaacacac
    15421 gattttgacg atcatcaatt gtgattcgcc agaagaatgg aaggaaaaca gacagcttgc
    15481 agcaagtaag actcaagcct taagttacgg tatccatcct tggaaagcag atagctatac
    15541 gtttgaacaa gttgagcctt ttttgaaaaa agcaaggatc atcggtgaaa tagggttaga
    15601 taatatttgg acgaatgtac cgatgactac acaaaaaaaa gtatttgagc gacagcttgc
    15661 ttttgcagcc ataaatgaga aacctgttgt actgcacaca aaaggatgcg aaaaagagat
    15721 cttaaattat atccaagctt accctaatca ctatttgatc cattggtatt cttctttgga
    15781 ctatcaacaa gactatattg atttaggctg ttatttcagc attggtcttg atttgaaaaa
    15841 gaatccagca gtctggcaac tagctaaagc agtcccaatc gaccacttac ttattgaaac
    15901 ggatggacta catgcagcag agtgggcttt aggggggatt ttttcagaaa aagattatgt
    15961 ctcactgctt gaagaacagt taaagacaat cgctgagatc aaagagctat cagttgaaga
    16021 agttaaaaaa aatacttatc aaaacttgga acgtttcatt agattaggta aataaaaaag
    16081 agatgtgaca caactagtgt cgcacctctt tttggctttc tttgtataaa agtaaactgt
    16141 ttgattaata aatgaatctt agtaccaacc gtttgcttcc cagaatgctt tcgccgcttc
    16201 ccaagaacca taacgtgaag taacatattg ttctgctact ctttcttggt ttgcagcaga
    16261 gtagtcacca tttaagtaag aagaatctaa ttggtaacgt ccgatgtaac gtccgttcgt
    16321 tgctgtgtaa gaaccgcttg attctttttg tgcgatccat tcttttgcag agcttgtgct
    16381 tgctggagta gcagcagttt ctgttacagc aggagcaggt tgtgtttcag caacaggcgc
    16441 tgcttgtttt tccgtttgaa ccgtttcttg tacaacaggt tgttcagctt ggactggtgc
    16501 ttcttgaacg gctgcttgag gttcagcagc tgcttgtgca gagccttctg ttgggattgt
    16561 taattgttgt cctgagta
//
LOCUS       DBBGSZ010000051        15153 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.053, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000051 DBBGSZ010000000
VERSION     DBBGSZ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15153
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.053"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            4..2376
                     /locus_tag="ACIZE5_002367"
     CDS             4..2376
                     /locus_tag="ACIZE5_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArdC-like ssDNA-binding domain-containing
                     protein"
                     /protein_id="HGC6109480.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIREEIERFEKGESSFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGEFEESKKYQATSEEEKVAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2437..3897
                     /locus_tag="ACIZE5_002368"
     CDS             2437..3897
                     /locus_tag="ACIZE5_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HGC6109481.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3908..6112
                     /gene="topB"
                     /locus_tag="ACIZE5_002369"
     CDS             3908..6112
                     /gene="topB"
                     /locus_tag="ACIZE5_002369"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HGC6109482.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6128..6277
                     /locus_tag="ACIZE5_002370"
     CDS             6128..6277
                     /locus_tag="ACIZE5_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109483.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6352..6945
                     /locus_tag="ACIZE5_002371"
     CDS             6352..6945
                     /locus_tag="ACIZE5_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HGC6109484.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6958..7857
                     /locus_tag="ACIZE5_002372"
     CDS             6958..7857
                     /locus_tag="ACIZE5_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HGC6109485.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7860..8357
                     /gene="ssb"
                     /locus_tag="ACIZE5_002373"
     CDS             7860..8357
                     /gene="ssb"
                     /locus_tag="ACIZE5_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGC6109486.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            8723..8983
                     /locus_tag="ACIZE5_002374"
     CDS             8723..8983
                     /locus_tag="ACIZE5_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109487.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9428..9634
                     /locus_tag="ACIZE5_002375"
     CDS             9428..9634
                     /locus_tag="ACIZE5_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HGC6109488.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGQRAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9655..9885
                     /locus_tag="ACIZE5_002376"
     CDS             9655..9885
                     /locus_tag="ACIZE5_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109489.1"
                     /translation="MTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLVEDAPTML
                     FEDLVKIAGYELHYQENMETYENEYWLTKLEN"
     gene            9900..10337
                     /locus_tag="ACIZE5_002377"
     CDS             9900..10337
                     /locus_tag="ACIZE5_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109490.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            10330..11037
                     /locus_tag="ACIZE5_002378"
     CDS             10330..11037
                     /locus_tag="ACIZE5_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109491.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
     gene            11201..11401
                     /locus_tag="ACIZE5_002379"
     CDS             11201..11401
                     /locus_tag="ACIZE5_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109492.1"
                     /translation="MNKIIPLLFVLCIGEILMRHGAAVHLNFVVFLGILVFCLIFWRF
                     VLALVSLLFKLIAAIFFIGLFR"
     gene            11417..11596
                     /locus_tag="ACIZE5_002380"
     CDS             11417..11596
                     /locus_tag="ACIZE5_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109493.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            11937..12200
                     /locus_tag="ACIZE5_002381"
     CDS             11937..12200
                     /locus_tag="ACIZE5_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HGC6109494.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            12194..12544
                     /locus_tag="ACIZE5_002382"
     CDS             12194..12544
                     /locus_tag="ACIZE5_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HGC6109495.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(12568..13182)
                     /locus_tag="ACIZE5_002383"
     CDS             complement(12568..13182)
                     /locus_tag="ACIZE5_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6109496.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRL
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            13496..13918
                     /locus_tag="ACIZE5_002384"
     CDS             13496..13918
                     /locus_tag="ACIZE5_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109497.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            13928..14131
                     /locus_tag="ACIZE5_002385"
     CDS             13928..14131
                     /locus_tag="ACIZE5_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109498.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            14342..14926
                     /locus_tag="ACIZE5_002386"
     CDS             14342..14926
                     /locus_tag="ACIZE5_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6109499.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         5578 a         2450 c         3059 g         4066 t
ORIGIN      
        1 gacatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ttagtacgat tgcaaaatga attaaatgaa caaatcgaaa agatgtttga acaccaaaaa
      121 atgacgaacg gtcaaccaat gaacgacaag aggaatggcc gttcatggtt taaccagcaa
      181 gaacgaatcg aaaataaagt ccaaagtctg agagaagaga tcaagcaaca agaaaaacag
      241 gtagaaaaac ttgaaagaca agaagagcta aaggaaatgg gttataacaa gtacggcgga
      301 ctagatatga cgatcgaaaa tattccaaga atcagagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcgt ctttttcagc cgccacgatc cgaaaatatc aacggaagtt ggaaacatta
      421 gaacagctga aagaaaaatc agaaaaagga aaagaaaata tcctccctga agtacaagcg
      481 atcattgaca gcggacgagt aacgcaatgg aaaaaaaatc cgaccattta ttttctgaaa
      541 ggctatcgaa aagtcgcttt agaactgaat gaaaacgggg aatttgagga atctaaaaaa
      601 taccaagcca catcggaaga ggaaaaagta gctgttcgtg aattacttga agaggctgcg
      661 ccaactgatt ctctgaagga gaaagaaaac gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggagaga tcgtaacatt agaattgatc
      781 gatcaactca aaacgttgga caaccaatac gctgcagaag caggttatta taaattctat
      841 tttgaagaag tgaagaacgg agaagtagtc gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaacccat ctatttagag ttagcaaaat tgtgcgaaca agtacctgag
      961 aaggaacaaa aacaatcggt caaaaatgaa cctgtttcga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taaacaagaa
     1081 gttaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttctcctgaa
     1141 gacgtcaaag aacttttgaa ctttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcttgtt taggtcgtgc cgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaagggt tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaacctta ctatacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacag ttaaaacctg aagactatcc gaaaatcttt
     1501 ccgaaccgtg tctttgattt tcaattggat aaaaaaggac agtcagaact tcaagctggg
     1561 attcaagcgg tagccaacaa tattggaata caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacgtggg gcgtatgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cctacgcagc atttagctac aagtattcat
     1741 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
     1801 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac gtcggagaaa
     1861 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagct
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
     2041 aagcaggagc ataaaaatac tttagaaacg ccagagaata agaatattgt gcccgttggt
     2101 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtaat tttaaaagga
     2221 aaaagttatg gaaaagagat ccaaacggcg ttaccttcag aagaatttgc gctaggaaat
     2281 ccattccgat tttcacttga gacagtgtca gaagtggcaa aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgt gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt tttaaaatga ccgagaaaaa aatgagtctt
     2461 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     2521 gtcaataaag gacgagatta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
     2581 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
     2641 ctttttttca tagacaaaga gatccaagac cctaagcaac aatttaaagc agccactgat
     2701 tttattctaa agaatgaaga caaaacagaa cgagtggaaa atcttcattt tgaaacagaa
     2761 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
     2821 aaggaagaac gaaaactacc agagtggctg attgattatg cagaaaaaga agggttgatt
     2881 gccgaactaa agccaaaata tgaacggcaa aatttcttag ttcgagacga tcgtttagat
     2941 catgcggtcg cctttttatg gaaagatcca cagacaaaag agacagtagg ggcgagttat
     3001 caaggaacgt tcattgatta tgaacgtttt ggtgagagag gcacatataa gcatatagat
     3061 aaaaattcga cagcgaatca tggctttaac ctaaagatcg gtgaccctaa gcagataaaa
     3121 ttttttgaga gtagtattga tttacttagc tatgctgcac tgaatcgtga tcagttaaac
     3181 gatacgtggt tagtctctat ggaagggtta aaacaccatg tgatcagtca ttattttggt
     3241 gaggcagtat ctgaattgag aaagaaacaa gcctttcctc aatccatcga gatttgtgtg
     3301 gataatgacc gtgcaggaca tattttctac gaaaaagaac aattaatggg cgcagtcgat
     3361 ccatttacga atcagaaagt acgttgtgaa cgaggaatcg ctaatgattg gcaagtgcca
     3421 aaagaataca aaatcattta tgaagaagtc gcaaaagaag aaaaggtcac accagaagct
     3481 attatggcca tacacaagac agaaaacaat ctgcaattaa cgaaccaact ggtttccgct
     3541 cacaaagtaa atgcgttttt tggccagcag ctttctgtta acgattcaat agaagccatt
     3601 aatttgaaag atatttgtag agaagtcgca aaagaattaa aagtttgtga acgcgtggat
     3661 ggtacgtacg attttgatcg tttttatcaa gaaaaagggg atattaatgc gcagattctt
     3721 ttctcttata aagcagaaca atactacaaa ggctataaaa atcatgaaca tgaatttgta
     3781 cctgaagtaa aaaaggactg gaacgatcaa ttgaagcatg agatccagca acaagaaatc
     3841 agaaagcaaa aacgtgccat gttgtttcaa caaggcagac aacaagaaag ggagtgaaat
     3901 cgtcatgatg aaaaccgtta ttttagcaga aaagccgtca caagcgaaag cttatgccga
     3961 tagcttctct aaagccactc gaaaagacgg gtattttgaa atccaagatc gattgtttcc
     4021 tggtgaaact gtgatcacgt atggttttgg tcatttagtc gaattagatt cgcccgatat
     4081 gtacgatgaa aattggaaac aatggtcatt agaacatttg cctattttcc ctacacatta
     4141 tcactatcat gttcctaaag ataagaaaaa gcaattcaag gtggtgaaac agcaacttca
     4201 atcggccgac accattatta ttgcgacaga tagcgatcgt gaaggggaac tgatcgcttg
     4261 gacgatcatt caacaagtag gcgccgatca aggaaaaacc tttaaaagac tttggatcaa
     4321 ctccttagaa aaagaagcca tttatcaggg attccagcag ttacgagacg caaaagagac
     4381 ctatccaaaa tttgaagaag cacaagcacg tcagatcgcc gattggttaa ttgggatgaa
     4441 cggtagccca ctgtatagtt tactcttgca gcaaaaaggc ataccaggaa gcttttcctt
     4501 aggcagagtc caaaccccaa cgctttacat gatttatcaa ttgcaggaaa agattagaaa
     4561 tttcaagaaa gaaccttatt ttgaaggaaa atccgaagta atcgctcaaa atggcgcatt
     4621 tgatgcgaag cttgatccga atgaaaccca agcgacgcaa gaagcatttg aagattattt
     4681 aaaagaaaag ggggttcaat tgggaaaaca gccaggcatg attcgccaag ttgaaaccga
     4741 gaaaaaaagc gcggcaagtc cacgtctttt ttctctatcc agccttcagt ctaaaatgaa
     4801 tcagctcatg aaagctagtg ccaaagacac tttggaagcc atgcaaggct tgtatgaagg
     4861 gaaatatcta agctatccgc gaacggatac cccttacatt acggaagggg aatatgcgta
     4921 tctgttggat cacttagacg aatacaagca ttttttgagg gctgaagaaa tttcgactcc
     4981 tattcataca ccgaatagta ggtacgtgaa caacaagaaa gtccaggaac attacgcaat
     5041 cattcctaca aaaacagtta tgacagaagc gacgtatgaa agtctgacac ctttacaaca
     5101 agcgatttac gagcaagttt taaaaacgac agtggcgatg tttgcggaaa aatataccta
     5161 tgaagaaaca acgatcttga cgcaagtcca gcagcttcag ttaaaggcaa tcggaaaagt
     5221 accgatagat ctaggttgga agaagttatt tggcaaagag agcgacggaa aagagaagga
     5281 agaagagccg ctacttccta aagtgacaaa aggagaaatg gtgacggtag atctacaagt
     5341 ccttgagaaa gaaaccaagc caccacaacc ttataccgaa ggtacgttga tcactgcgat
     5401 gaaaacagct gggaaaaccg tggatagtga agaagcgcaa tccatattga aagaagtgga
     5461 aggaatcggt acagaagcga cacgggcgaa tattattgaa accttgaaac aaaaggaata
     5521 tatcaaggta gagaaaaata agcttgtggt gacgaataaa ggggttttgc tttgccaagc
     5581 tgtggaaaaa gagccgctgc ttacgagtgc cgaaatgacc gccaaatggg aaagctactt
     5641 gttaaagatt ggagaacgaa aaggaacaca aaccactttt ctagccaata tccaaaagtt
     5701 tgtctctcac ttattggaag tcgtcccagg acaaatccaa tccattgatt ttggatcgac
     5761 gttacaagaa gtgaaagcag ccagtgaaaa gcaagaagcc gcgcgtcatt taggaatttg
     5821 tccaaaatgc caggaacaag aagtcttact ctatcaaaag gtggcagctt gtacgtctga
     5881 agcctgtgat tttaaattat ggacaacgat tgccaaaaag aaactcacag cgacacagct
     5941 gaaggagatt attcaaaata gccgaacaag ccaaccagtg aaagggttaa aaggtcagaa
     6001 gggttcgttt gaagcaacga ttgttttaaa agaagacttc actacaggct ttgaattttc
     6061 tgaaaagaaa aaaacgaact tcaagaaaag aacacgacgc acgacaaaat aatggagggt
     6121 taatcttatg cgtaatacaa cacacaaaca acaagaaatc gaaaatcaaa aagccaaaat
     6181 tcgttcagaa caagagaaat tacgtgccag taaaagaaga cttcagcaat taaagaacca
     6241 gcaacggatt caaaaagaaa tcgaattaga tcgatagaca ttaaccttgt tacaaataca
     6301 ctatcatgat atatttaatg tagtgtattt gtaacaaaag gggggaagta aatgcaagag
     6361 aaactgaaag aattgttggc tattcgcgat ggaaatttat ctatgaagga agccagaaaa
     6421 ttaggaatcg cagcaaccac tgtacaaaga ttggtgaatc aaggaaaatt gatcaaagtt
     6481 gatcgtggtt attatgtaga ggatggtcat ggaatagatg atttattttg gcttcagcaa
     6541 cgtttttcca ggggaatctt ctctcatgaa acgactttag atatttacca gctttctacg
     6601 aatatgccga aattcattca cttaactttt ccccatggat ataacgttga tcgttcaatt
     6661 acaaaagagc agcagttaca atttcatttc gtgaagaaag aagtttatga actaggaaaa
     6721 gtagagggaa cttcctttca aggaaatcct attactatgt atgataaaga gcgtacactt
     6781 tgtgatattt ggaatccgag atatgaaatt gaatatgaaa tgaaattaga agcattaaaa
     6841 gagtacatgg aagacccatt gagagatcca agtaaattaa gagattacat gacaaaacta
     6901 catgtagaaa aagaaatgaa ataccacatg caaagcttat attgatggag gaaaaagatg
     6961 acaccgacac aatttgcagc aaaaacaaga aatttagcaa agaggacagg attaaatgca
     7021 cagttagtac aacggcattt tatgatggat cgtttaattg aacaaatttc tgaatctaag
     7081 tataaaaatg atttcatttt gaaaggtggc tttttattag gatcaaaata tggaatcgat
     7141 agaaggacga caattgatat cgacacgaca tttagaaata gcaaattaac tgaagaaaaa
     7201 ttgaagagta tttttaatga tttaactagg aaacccacga aagaaggtat tgttttctct
     7261 attcaaggaa tgaaggaaac aagagaagcc gatttttatc ctggatttca aattaaattg
     7321 gtggctaatt tagagaaagt acgtgtgcca tttaaaatgg acgtgacaac aggagattct
     7381 atttatcctg aagtagatac acactatcac caattaatgt ttgaagataa aaaggtggag
     7441 attccagctt atccaacagc acaaattatt gcagaaaagc taagtgctac gttcagcttt
     7501 ggcacagata attcgagagc aaaagattac tacgacttat ttaccattcc gaaactagaa
     7561 aatatcgata cgaaagagtt atacaaaagt gttcgaaata catttacaaa acgtggggat
     7621 acaaaaccgt tgtcctttta ttatgaaaga gaaatggata agatcatagg aaatgactat
     7681 ttggaaaagc agtgggaaaa atatcgctca gttaacacgt ttgcgaattc catttcattt
     7741 acagatacag tcaacgaaat tgatcaccta atgaaaagtg tgatcaaaat tgaaaatcaa
     7801 gaaagaaaac ggcagtttaa aagatcacaa caaatgaatc aagaaatgga gagataaaga
     7861 tgatcaataa tgtaacttta gtaggacgct taaccaaaga tccagattta cgttataccg
     7921 cgagtggtac tgcagtagcg acttttaccc tagctgtcaa ccgaaatttc acgaatcaaa
     7981 acggcaatcg agaagctgat tttattaact gtgtgatttg gcgcaaacca gcagaaacaa
     8041 tggtgacatt agctaaaaaa ggtagcttga ttggtgtagt tgggcggatt caaacgcgga
     8101 cttatgacaa ccagcaagga caacgtgtgt atgtgacaga agttgtggcc gataatttcc
     8161 aactattaga aagcaaagca gcgacagaaa gccgtgcgca cgctgatcaa tcgtccacca
     8221 gtccaagcac caccactttt gaacaacggg atacagcgac gcctaataac aatggattga
     8281 acgctttaca gaatccattt gggaatccat ttggtggaca atcaatcgat attagcgatg
     8341 atgatctacc gttctaagta gcattttcta ttggttgcat ttgctacggt ttatgttata
     8401 atttagtcaa caaaaagaat tttcaatcta taaccaaaaa ccactagctg gcgggctagt
     8461 ggttttcttt tacgtttcta ttataagaat taacgggtag gcttactgtc tttcttggca
     8521 aatttacaat caagccattt gcagatatag tgcgcggcta cttctgccat gattgcaaaa
     8581 acaaaatcaa aaagaatttt caaacctata acctcctccc cttgccagat taggccgggg
     8641 tagcagacag caagactatt atagcataat tgaaatatcc aaatgattgg atttttgcta
     8701 taattttagc gaggtgattg tgatgaacaa atatgttggt ttgcttgata aaatccgagt
     8761 aataaaaacg caaccgttat tggttcgctt tactttacaa acgattcatg aatcgattaa
     8821 ttgtgtagtt gcagatattg aaattatcga taaattgcta attatggatg atggaaaata
     8881 caatattgcc gtcacaggtc acttcaataa acgaaatcag ctagttattg ctagcatgta
     8941 tgttagaaat cccgatcatt ttacgcgatc gatgggcata taaaaaaaga agagttgcaa
     9001 tcctaatgta ggactgcagc tctttttgtt ttacatagaa acaagaaaaa tgaaaaggcc
     9061 tttttaggaa ggcgcgagcg ccttctcaat tgaaaaacct ctctcactcc aaccgccacc
     9121 gccgttcgag aagaaaggaa gtgaacgttg cacgttcact aagataaagg gtcttgcaaa
     9181 gcaagacaaa atagaaaaaa cttcctctca ccaaaaggtt cgttcctgtt cgttatctct
     9241 ttattgattt gccagaccgg caacaagttg ccttttatca ccaaaaagcg acaaggacaa
     9301 gggtaaatgg cacgctgcgc gcccttgtcc ttgtcgcttt tcgttgattc attctggcca
     9361 acaaatcaat aaagaaagaa ctaacgaaag gaagtaaaac ctttcctaag aggaggcaga
     9421 atcaatcatg cgaaagaaat ttgattattg gggtgttccc ttcagcgaat tattcccaaa
     9481 ctatcatgca ccacatactg tcgaatgcga ttgtggacaa agagcgaaat gtatcaaaag
     9541 ctatcgtttg tatcaatgtc caacatgcgg aaaaaaatac accttgtctt atggcgatta
     9601 tattttgatt gatgagaaag gaaagaaacg ctgatgaaaa cataacataa attattgact
     9661 gtaaaagaag tcgttcaaat tttggtggac aaagaagtca tttctgaaaa agtagcagaa
     9721 gctttactta ttccgcggta ctggacgata gaaacccctt tagtagagga tgcaccgact
     9781 atgctatttg aagacctagt gaagattgca ggatatgaac tgcattatca agaaaacatg
     9841 gaaacttatg aaaacgaata ttggttaacc aaattagaga actaaaaagg agaaaaaata
     9901 tggctcaaaa ttactatgac gaatttgtca aattaccttt ggataaaatg gcacaaaaaa
     9961 tggaggatat gacattccta taccatgaga cacgtgttcc aaaaaaacat tataaggaaa
    10021 gattgtcggt agctgtggaa gaaatgattg aatcaggtgt cgaaatgaat ctcattgcga
    10081 cgtactatcg aacactggaa gaactgaaaa aacaaaatgc aaaatggttt ttccaagcct
    10141 tactatgctt ggaagtaggt gtcaaaccaa gcactattaa accttctgaa tatcaagctt
    10201 tagaactaac gtatgggaaa tttgtcgaaa cgaaaaaagc caagactgtt tcaagtgaat
    10261 ggttagatta ttttgaaaat atcaataagt atggcgccta ttacaccatg aaaaaggagg
    10321 acaacgaaaa tgaataaggt gatttatcaa ctaacaacgg aagatgtgtc acacttttta
    10381 acaaacaaag aacatttgaa tgaagtaatc agacggattc aaaaagactt tagttgtatg
    10441 gaagaaatga agtactttat tcaaagagtc gaagaacaat tgtatttgga aagtgaaacg
    10501 agtcaaacga aggttacagt cagcaataat tatttagacg tgtataaaca tcgtcctgaa
    10561 acggtaaaaa aaggaacgga gcttctacga ctagaaacag aaaaatacat catgaatgtt
    10621 tacctagaaa ggagtgaact ggtcgaaaac tttgtcagct gcacgatttg caggaaacac
    10681 tattactcag aatcagaata ttattcaatt tttgagagca tggaattaat ggaagaagaa
    10741 atggaagagc taaacagcaa aaatgcgacg atagacgatt attatcttgt atttactaga
    10801 tttttgacgt gtggaacgga atctatcgtg ttaatgggaa tggattatga actcgctgta
    10861 cccgaagcat ttttgaggga atatgtagaa gaagtagata acccaggcga cgactggtac
    10921 acgactttaa ctgatttttt agatacctac acttacgacg atacagaaga aatccaaaat
    10981 gaacttgacc gtaaacgaat gccatatcaa cgatttgaaa ggaaaaaaag gcaataatca
    11041 tttataccga aaagtgagaa tgtgtgaaat aagaacaaaa accttgaaat taagggaatg
    11101 gttcttattt cgcaccaatc gctccaaccg cccccgccgc ttaggtggtg cgaaataagc
    11161 gggcaaagcc cgataaccta agagaaagaa ggagatccat atgaataaaa tcattcctct
    11221 gttgttcgta ctgtgtattg gcgagatact tatgcgtcat ggtgcagctg tacatttaaa
    11281 cttcgtagta ttcttaggaa tactagtatt ttgtttgatt ttttggcgct ttgtgttagc
    11341 ccttgtgagt ctactattca agttgattgc agccatattt ttcatagggt tatttcgatg
    11401 aaaggagaga gtactaatgc caattgcaat aggaaataaa cggttacccg tgacattaga
    11461 tgaaaagaga caaaaagaat tgcagcaact aaagcagaag tacggaaaaa gtgaatctaa
    11521 gattatgtgt attgcgttag atctattgat cgcgcaagaa aaagcaggat ttgatatacc
    11581 agcactaaaa aagtgacgtc acttttcatt tgaagaaaca aaagtgatag cacttaattg
    11641 ttcctactat ttagaatatt ttctatgtcc tttttattcc attttgtatc aataactatg
    11701 aaatctttaa agtatccaga agagattatt tttagatcaa tttttttctt acctgattct
    11761 aaagattttg ttttcttaaa catattatga tttcctttcg actattttca tataaatgtt
    11821 aacatagttt atggattcat ggaatgttaa tctaatttaa tagaaaagga taattaagta
    11881 tatacgtttt ttcttatgta tgttatacta tgtatataca gaaagaggtg tctactatgg
    11941 aaatgttacc tataaaaaaa tggggaaata gtaatggcct tagattgcca aagtatatta
    12001 tggaatatct tggaattcat acagaagaca aagtgaagat aatacaagaa gaagtaaacg
    12061 gtcagaagcg gctaattatc gaagcggcta atatagaaaa tgaattaaca attgaacagt
    12121 tatttgaaaa ttacactgat gaaagaaatc atgtgacgat tcaaaattta ggtgaagcag
    12181 taggtaatga aaaatggtga gaaaacctag acaaggcgat attctattat tgaatacagc
    12241 acctcgatct ggacacgaac agacaggtaa aagaccttat attgttttaa gtcatgatat
    12301 tattgcggat tatagtaacg ttgttacagt tgctccaatt tctagtacaa ctagaaacta
    12361 tccgctatat gtaaatataa actcagaata tgaaatgaag acaacaggaa aagtattatt
    12421 agatcaacta acgacaattg attatgaagc cagagagtgt atttttttgg aaaaagcgca
    12481 tgatagttta gttgaggagt tattgatgaa agttagaaca gtttttcaaa aagtaagcaa
    12541 ataaaataga aacagcagca tgatcaacta ttcgtgattg accatgctgt ctttttttat
    12601 tctatatacg gtttgtctcg taacattgta gtcttttgca atcttagcga tcgcaacacc
    12661 tttttttaga tcctcaacga tgtttttata aacaagacga cgttggggat cttttgcatt
    12721 ggcactgtat agcttaggac gtcctttata aacaccgttc gcttttgcaa tcttaatgcc
    12781 ttgtgcctga cgtcgtttag attcggtacg ttcttgttca gcgatcatgg ccaaaatttg
    12841 aatgatcaaa tctttaatga atttatccag gagaggattg ccaattgctt cggccatgat
    12901 cggtagactt gtgatgatca gctgcacatt tttcttcttc aagtaattga ctgaagcgat
    12961 gatctcgtcg taatttcttc caagtcgatc aatagcttcc acaataaaaa tatcttgatc
    13021 tcggacgaaa tccagtgctt cttgaaaaac aagtcgatga gtaatcgttg cgccagattg
    13081 tttctcaatg aaaattctct ctgcaccgaa ttttttcatt tcttcaatct gccgttgttc
    13141 attttgatcg atggatgaga cacgtatgta tgcaactctc aaaattttta cctactttct
    13201 gcaactattt aaaaaacacc ctaatcatac acgagaaaac cagatttttc aatgtcgcgg
    13261 tcgtgtctag ttagggtata ccttatatag acaaaaacta atgatggagg aaatagtatg
    13321 tgtcactttt ctttttaaat ggcaatattt tttgtaaata aatgtcaatc aagaaaattt
    13381 aaacgattat gacattaaaa atatatttta tgaattttct agtatataac ttgatttatc
    13441 tgttaagatt tattaagaaa acgttttctt atttttgatt tcgaggtgat agacaatgaa
    13501 aaataagttt attttatctt taggtatttt aactattgga attagtgtaa ctggaactac
    13561 aattcctaca tttgctgata gtacaaatga accaactact gtagtagata ataaccaaga
    13621 attaactcct ttagatagga acggaatagc cattggtaac ccaactaacg acttaactgt
    13681 tactgaaaat tatttaatag tttctccatt acttgctcga gcagcttcta aaacgatacg
    13741 agtgacagga acgatgattt ttgataaagt tggttggcct tctagacctc ctcaatcacg
    13801 gaattggaaa gaaaaaagaa atggttattg gtactatgga aaattgtatt tacaaagtta
    13861 taaatcagct ggaaacaatt ggattgcgac ttattcagga accttaacta gaaagtaggg
    13921 attttttatg ccagaatttg tgaacacacc aaatttttat caagatagcg atattctaag
    13981 taaaattaat ttaccgaaag aagaatcagc tttacaagtt cagcgaactt tacaggagac
    14041 acaaaaaatt caaaaatcaa tttctaatct agaagattct gaagaaaaaa gaaaaaaaag
    14101 agaccaaaaa acatatcaaa aagaaaaata atgattttaa aaaaagagtg tctagtcgac
    14161 attctttttt tctaattgaa agtgttcata aaatcaccca tttctggaca ctttcttttt
    14221 ttgctttatt tttcaaaaaa acaattcatt tcatgttcat aaacccataa caatatctat
    14281 gttcagttaa actatatgga taaagttatg ttacaataaa attaatgaag gagtgatttt
    14341 tttgaaaata ggatacgccc gggtatctac tggtttacaa aatttggatt tacaagaaga
    14401 cagcctaaat aaatttggtt gtgaaaaaat ttttactgat catatgagtg gggcaaaaag
    14461 taatcgacca ggattagaaa tggccattga ttttgttcgc tctggcgata cacttgtcgt
    14521 ttggcgctta gatcgtttag gtagaaatat ggaagatttg atttcaatcg tcaatcgact
    14581 gaatgagcgt ggtgtgagtt ttcatagtat tcaagaaaat attacgatgg acaaatcaag
    14641 ttctacagga cagctcatgt ttcatttgtt tgcggcattt gcagaatttg agcgtaattt
    14701 gatcctggaa cgatccgcag caggacgagc agctgctcgt gcaagaggac ggtttggtgg
    14761 tcgtcctgaa aaattgtctg aacaagattt ggaattactg aagactttag tggatagcgg
    14821 tacacctatt aagactattg cggaacggtg gaacgtctca agaaccacca tttatcgtta
    14881 tttggcaaaa atggaggaga aaaatggaaa gacaaattct cattagtttt tgtcatttaa
    14941 tgctgaaaat ttttgccatt tatctagaaa agtgacaata gtatgagaat tttttgtaag
    15001 tgtctactga taacttattc tcaaatgttg taaggatttt attcatttgt taatattaaa
    15061 gaacggaact ccaaaaaagt ccgtactcta atttgcagtc tctcactctt ttagagtgag
    15121 agtttttatt agattttcaa attaattagt aaa
//
LOCUS       DBBGSZ010000052        14128 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.054, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000052 DBBGSZ010000000
VERSION     DBBGSZ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14128
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.054"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..242)
                     /locus_tag="ACIZE5_002387"
     CDS             complement(<1..242)
                     /locus_tag="ACIZE5_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGC6109500.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNEL"
     gene            complement(235..1827)
                     /locus_tag="ACIZE5_002388"
     CDS             complement(235..1827)
                     /locus_tag="ACIZE5_002388"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HGC6109501.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(2337..3062)
                     /locus_tag="ACIZE5_002389"
     CDS             complement(2337..3062)
                     /locus_tag="ACIZE5_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109502.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(3216..3542)
                     /locus_tag="ACIZE5_002390"
     CDS             complement(3216..3542)
                     /locus_tag="ACIZE5_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109503.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(3579..3944)
                     /locus_tag="ACIZE5_002391"
     CDS             complement(3579..3944)
                     /locus_tag="ACIZE5_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HGC6109504.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(3981..4196)
                     /locus_tag="ACIZE5_002392"
     CDS             complement(3981..4196)
                     /locus_tag="ACIZE5_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6109505.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            4325..4660
                     /locus_tag="ACIZE5_002393"
     CDS             4325..4660
                     /locus_tag="ACIZE5_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6109506.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(4736..6733)
                     /locus_tag="ACIZE5_002394"
     CDS             complement(4736..6733)
                     /locus_tag="ACIZE5_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109507.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(6831..7106)
                     /locus_tag="ACIZE5_002395"
     CDS             complement(6831..7106)
                     /locus_tag="ACIZE5_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6109508.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            7338..8072
                     /locus_tag="ACIZE5_002396"
     CDS             7338..8072
                     /locus_tag="ACIZE5_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6109509.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            8111..9253
                     /locus_tag="ACIZE5_002397"
     CDS             8111..9253
                     /locus_tag="ACIZE5_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6109510.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(9881..10366)
                     /locus_tag="ACIZE5_002398"
     CDS             complement(9881..10366)
                     /locus_tag="ACIZE5_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HGC6109511.1"
                     /translation="MVRRVFFSFHYADVTRAMVVRNSWTLRGTKEAGFVDKAEFEKVK
                     RNGDIAIKNWIDNQLIGTSVTVVLIGKETLDREYVKYEIQESYKRGNAILAVNIGKIK
                     DFNQMTTTSQSVIKIIGQKPDGEYLWFDEIIDGQYDYISDDGYNNLGTWIDSAAYKKG
                     K"
     gene            complement(10368..11039)
                     /locus_tag="ACIZE5_002399"
     CDS             complement(10368..11039)
                     /locus_tag="ACIZE5_002399"
                     /inference="COORDINATES: protein motif:HMM:NF037286.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109512.1"
                     /translation="MSRFSINVVEVDDYSEITDILKSIRKKYLRKTIFISGSAVDYTP
                     FTSESKGLKFVEKLAYRLSESGYRIVSGYGLGIGNSIVSGVLKQRRNLRKNNIQDVLS
                     LRPLPLDMPHEWRRYRENIIAESGISIFVFGNKLESGEIVTADGMIEEFELSVQNENI
                     VVPIGFTKGASKVLFDKIQENFSDYFDDSLKSKFQALEKLDTEGEVDKKVEQIVSLIN
                     SIQED"
     gene            complement(11302..12495)
                     /locus_tag="ACIZE5_002400"
     CDS             complement(11302..12495)
                     /locus_tag="ACIZE5_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6109513.1"
                     /translation="MSEKRRDSKNRVLRSGESQRKDGRYAYKYVDTFGKPQFVYSWKL
                     VPTDKTPAGKREDISLREKEKEIQKDLDDGIDTIGKKMTVCQLYAKQIRHRGNVKHNT
                     KLGRERLMRILEQDRLGSCPIDSVKLSDAKEWALRMKEKGLSYKTINNDKRSLKAAFY
                     TAIQDDCIRKNPFDFQLSDVLDDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVI
                     LLGTGLRISELCGLTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNE
                     EVYQAFQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNKSHE
                     EALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNYYAHATFDSARAEM
                     ERLAA"
     gene            complement(12579..12779)
                     /locus_tag="ACIZE5_002401"
     CDS             complement(12579..12779)
                     /locus_tag="ACIZE5_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HGC6109514.1"
                     /translation="MNHDVPIWEKYTLTIEEASKYFRIGENKLRKLAEENPASGWVIM
                     NGNRIQIKRKQFEKIIDTLDTI"
     gene            complement(13203..13436)
                     /locus_tag="ACIZE5_002402"
     CDS             complement(13203..13436)
                     /locus_tag="ACIZE5_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6109515.1"
                     /translation="MKNPNYKGIELLPLSVIEAARAGDAGAVERVLQYYSGYMNKLCT
                     RTLYDENGYPHVCLDEAMKRRLEIKLIHAIVTN"
     gene            complement(13443..13874)
                     /locus_tag="ACIZE5_002403"
     CDS             complement(13443..13874)
                     /locus_tag="ACIZE5_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGC6109516.1"
                     /translation="MDAIPRDYEARCMFDAFCKTVLRNEAKSYLAEMKRRRDREVSLS
                     SLSQADLDKLCTVDHYPSDSFTFSSHGYDLHINNELVAEAFAALPSMEQSILILHCVL
                     DMADGEIGGLVGMSRSAVQRHRTNTLSELRKQLKALMPKGG"
BASE COUNT         4295 a         2895 c         2269 g         4669 t
ORIGIN      
        1 attaattcat tatatttttt ttcagtaatt ttatatcttg tttcgtaatt atcataaata
       61 gcattttgtt gttcatagac aacaaaattg ctattagata caaagaattc tttctttaag
      121 gcactcccaa atggtcccct ccttactcca tcttttttat caagtaagca ttcaaactta
      181 cgctgttccc aagcttccgt aaatcctggg aaacgaattt ctggttgtat atcattactc
      241 atgtttgaac acctccagcg caccttgtaa ccacgcttca ttttcaggtg ttgtttgcag
      301 ggaagagata gcttctaaaa gttctttttc tagcacttgc tgttcttgtc gtatcttctt
      361 gatgtcattt ccgacatgaa ccatatcaat tggttcttct tcttcaaacg tatctacata
      421 gcgtggaata tttaagttat agtcattttc tttgatttca tcaaagtttg ccaaatgagc
      481 gtatttctcg acatcttttc tttcagcata ggtttcgagg attttttgaa tgttttcttc
      541 cgataattta ttctgatttt ttcctttgac aaattctcga ctagcgtcaa tgaataatac
      601 gtctcgagtt tggcggttct ttttcaatac aatcaccgtc gttggaatcg atgtcccgaa
      661 gaacaagttc gcaggcatac cgatcacagc ataaatactg ccgtcttcta gtaatttttg
      721 acgaatgacc ccttctgcag cgccacggaa taaaactccg tgtggcaaga cgatggccat
      781 agtccctgtt tccttcaaat gatagaaacc atgaagaaga aacgcaaaat ctgctttgga
      841 ttttggcgct aattttccat aacgattaaa ccgagaatcg tctaagaagg tcgtatctgc
      901 tgaccaatta gccgaataag gtgggttcat tactactgca tcaaatgtgt aaggttcatc
      961 tgttggccaa tccttattca acgtatcccc attgcggaga ttcatttctt cggcatctac
     1021 cccatgtaaa atcaagttca tttttgctag attgtatgtc gttgtattta attcttgccc
     1081 atgatattta acgttatctg ggtgagttaa gtagttacgc acatttaaca tcaatgaacc
     1141 tgaacccatg gttggatcaa aaacactaaa gaatcgtcgt tctttttgat ccaacgtcac
     1201 gatttgtgcc atcatatcag aaaccatatg aggcgtgtaa aattctccgg ctttcttccc
     1261 tgcttctgaa gcaaattgac tgatcagaaa ttcataagca tccccgatca cgtccccatc
     1321 gtgacctaaa acttccacgt cattcaattt cttaatgact tcggtaatcg tcacatttcg
     1381 ttgttgctca tctgttccta gtttttttga ttggagatcc acatcatcaa ataacccatt
     1441 aaattgattg taggtagatg ccaattgcac aaaggctttg tttagatcat tcaattggaa
     1501 cgttgcttgt tttgcttgat ccgctaagac gttgaaaaga tactctggcg aaatcgcata
     1561 ccccaaaata tcaacgattg ttgcaatcag atcttctttt gattcttcat ctgaaagtaa
     1621 ttcgcgatac aacatcgttt gtttgcttac cgtatcatat tcctctaagg attcatctgc
     1681 taaaagaacc acttgttcca acaaacggtc ggataaatat ttatagaaaa tcagtcccaa
     1741 taaataattt ttatattctg acgcatccat tttgctacgg agattatctg ccgcactaaa
     1801 taatttttga tttaattctg cacccaaaaa gatacactcc tatctcttat ttaaagttgc
     1861 tatataccct cttattttag catactccct tttagaaaaa gcaaaaaaaa aaagaaagaa
     1921 acttattctt gctaataaac tacgcgaaag gagtctaacg ttgtttgata taacttagac
     1981 tgatcgttaa cttatttttt atatttctac atagttatct ttagaaccat ttcagataca
     2041 tatgaaacaa ttacatatga ttttttcata aaaaaacagt actgtctagt agtataaaat
     2101 atacaaattt cttaaaaatt ttttcactaa aatcactacc tgaaacagtc taaaacactt
     2161 atatatcaac gtttaatgaa actatctccg tttcatttca gatacaaata aatatagtcg
     2221 ggctccaaat ccgaaaaaaa atacccccag tagcttatcc taagctactg gagatgtata
     2281 agtacggtca tataacaacg gggtagggta aataaatgaa aaagatggaa gaatcattat
     2341 tcaataactt ttttaaatac ttcgttgtaa tcagttacct gtccgttctt aaataccaca
     2401 gaataatctt ttttcccatt ttcaagtaac cgaagtggaa tatctttacc aactttctct
     2461 gtcactgcat tactgatacc tgttagatta gctaataaat ctgataaaga ttgagcatct
     2521 gtagaaatct ctgtatcagt atttatcgtg attcctttat cttcatttac aagtttccaa
     2581 gtaggtggta tagctgtgta tgtttctaca aatgaattaa gtttttcatt aagtgacttc
     2641 tcttttatat ttccatctaa aaactctgta tatatggctt gagctatact aaaacaaagc
     2701 tggccttgtt ctaataattt tacatcatta gttagtaaag ctgtgttcac gttatcaatc
     2761 gcttcaagaa gagtatcttt ggtgtcccta acagctttag gtgtgccttc tggaatttcc
     2821 ctacttgata cctcgtccat tttatcttcc ataaacccct taaaatcata tctttctccc
     2881 aaatccatag aagtttttga gaaagctttc atttctgagt ctatttcttc aataatattt
     2941 aacatgtctg atacatattg tttaggctga ttcgttttta atctatatgt ggtaaatatc
     3001 tcaattcctc caattatcaa taaaattgcc aaacaaatcc ataataattt tttctttttc
     3061 atttttcctc ctatacactg ctgttataac agtgactaat gtaaagattt tcccagcaat
     3121 catcagacta ttatttacag ggaatcaaaa aaactcctta gtaagcttac acctttagga
     3181 gttcctgttt gaacggtatg cataatacat ttaaatcaat ttaacattaa cacctcagta
     3241 tatggtatct ctacatatac acggtctttt tttggatagt actcgacatt tatattgata
     3301 gcacttccat tgtctaacgt agctttagcc cggtacgtgt tatcaccatt atcatgagtg
     3361 atcgtcacat catcacatgt ccgatttaag ttatactgtt cttgtaaaat ctgagttacc
     3421 aatggtacag atgacttctc tagtccagat gaacccgtca ttcttgaaaa aattatacct
     3481 ataatagcca atacaacgat acctataatg acaaacttct tattcatatt tactttattc
     3541 aactttttat ctcctatctc caaaatgatt ttctctcatc agtaactcat tgacatcccc
     3601 aatagtacac caaagatggc tccagctacc cctgctatca tcaaaatcgt acccatttgt
     3661 tcatctttct ctcgatataa gtaacccata ataacagcaa cagcaccaaa taccacagga
     3721 ataaatgcta atgatactac catagaaatc caaccaataa tcaaatacag cttccctgtc
     3781 tcttgtccat gtacgatttg ttccttcatt tcattaattg tctgctcagt acttttcttt
     3841 actgtgtctg ttccggttgt ctcatctgtt tcttgtaatg ctccgcaaaa ctggcaatac
     3901 ttactttcat ttgttatttc tttaccacat tttctacaat acatgtcttc tcctcctaaa
     3961 atcattcaat tgcttattag ctaactgttt actttattaa atacatcaga aaacagctca
     4021 tttattggta cacttaatat ctcagaaagc attttcattt gatagggttt aggaatcgtt
     4081 ctccctgttt gccacgaact tacacattgc tgtgtaacat tcattttttt ggctaactca
     4141 gtttgggaaa gtcctttttc ttttctgtat cggctgagat tacttacttt tttcatgatt
     4201 ctcccctcct gttttattat atacaacaat atgatgtatt tcaactcata aaatatataa
     4261 atacttcaaa tgtcattaca aatacaacaa cttgttgtac tctactgaga aggggggtgt
     4321 attaatgaaa cagaagcaat atgcaaaggt cattagagaa aagcgaaaag cactcgggtg
     4381 gacacaaaaa gaattagcta aaaaaatctt ctctacacaa caggcagtag caagatggga
     4441 aaattctgta acagaaccta acctcgatag cttaacagct ctttctagag ccctaggaac
     4501 ccctgtaagc cattttctag acaatgttga catagattat gaggaagagt ttttggctct
     4561 ctatcgctct cttagtactg aagatgcaat tcgaacaatt gactatatga agctattaaa
     4621 aaggcaagaa aatgaacgca atcagctatt gaaagattga aaaataaata acccaccgaa
     4681 ctttaacggt gggtgtattg agatgaaata agattaagag ctatggataa cctgtctagt
     4741 ttaatataat tgggtctctt ctattcctta ctctccgtcc atcatctctt gttacacttg
     4801 taaattgata aataggaact aattcaactc ctgataatat caattctttt attacttcat
     4861 ctatccctgc ccctttcgct agatatacta aaaaactact gcttgctttc acattgtata
     4921 gtttcttaat atccttagaa gctcgttcaa gagtgaatcc ttgtttaaca aagtagcctc
     4981 tgttttctat taaagcattt ttcacgctgt tatccctgac atttcgtagg cgttcacaaa
     5041 cagtgttaat aagttctttt tctgtcatta gatatgtccc ttgccacgat aagccctgta
     5101 aaacttcatg tgcttcatct aaaatcaatt gtttttcctt gctaagttct gatcgggaat
     5161 tttgaggaaa tactctttta gcctcttttt cgttaaaaca tatcttaacc cattcataag
     5221 aaaaatattg atatgtaaaa tgaaattttt ccagaagtgg aaggatatct tcattcaatt
     5281 tttgaatcac agaagttgca ttaaaaacgt ctaatcgata gacattgctt ctcttatgtt
     5341 taaagtttcc taacgctttc tcttccttta acctatttag gtattcgagc atcttcaaag
     5401 gaacatcttc atcatctaat ttttttatca atcctataaa agtcataagt gatagtaact
     5461 tattacattt atctatgtca taagttttac catagtaaga actcattttt ttagctaatt
     5521 gttcccccga caaaatacaa gtcacacttt ccttactatc atcaaaaaaa ttaacatcag
     5581 aaagcaagac atcatagaca cgtcgcattt cctctagata attccttatt gtcctgaaaa
     5641 gtttgtcttt cattgattca agagtgtcaa aaagtacttt tgattcctct ttcaattttc
     5701 gaaaatgtgt aggatacaag tctaggttct ctaatagcca attaaatgtt tctacccgac
     5761 tgtctttctt taaaattagc atcacaactc caataaaatt ttcactgata tcacaattac
     5821 tggaatgaca ataaaaaatg gaatgcccag ttttactggt aaaaatacta gcagagggat
     5881 tatgatcgtt gtgaaacaga catcttaagt ttttacttga cttaagtaat ttattcatat
     5941 caatggttaa caatctttca taaatctcat taaaagacat gtcggaggaa tcaaacaggc
     6001 agtctttaaa ccactgtttc atttcttctt tgtcgtcatt ttttatcaac ttaacaaaat
     6061 cggtttcatt gactagttca tactctctcc ctgaatcact ttgacaattt ttagaacatg
     6121 tcatggtaaa atcaatcgga agctcagtaa tatctaacat gttgtcttca ttaattatta
     6181 tcactgcatc tgacttatat cctccaaaaa acattctatt cgaagcattt acattgtcat
     6241 cacacccggg gatgttcttt ttcaagtatt cgtaaacagc aaccatttta ccatagtcag
     6301 taattgcttc ttttaataga aagacaatct tgtatttttc tagattttca gagtaccgaa
     6361 tacttttttg tatcgcaaac gcagaattat gaactaaatt gatagataaa accttttcta
     6421 tgcttaagta tctactatca tctttactca aatctactac cttccccttc tcatctttaa
     6481 cagtgttatc gacatccaga ataattactc tggtttccac aaaactctcc ttgtcattgc
     6541 ctttattctt tgtcttgctt ggaataaatg attgtgatga atttagtatc tctacaaact
     6601 catctcttgt aacttctcta tagttatcta aacacctatc tcttacatca gttttttctt
     6661 tttttgtaac tggcttctct aataattttt ctttatctac ataaattgga atattaatca
     6721 ttgatgtttc catttgtgtt tcctccttat aaaattctgt taaagactaa aacatacaga
     6781 taataaaaac aaactcttta ttactatatg ttttagtctt atttgtttac tcaaccttta
     6841 taccgttcca tgaaactatc aatatcagat tttttaaatc taatgaccgt atcaattttt
     6901 ataacaggta acccgtattg agaaacatat tttctaatcg ttcctactga tacacctaga
     6961 tattcacttg cctgctgata gtccatatac tctagagtga ctccagaaat aatgtcttct
     7021 agcataggct ttagcactgt aattatctct ttcacttgtt gttcaacttg tatagaaaca
     7081 atgctatcaa tgatttgtag agacatattt ccccctcctt tcgtgattgc ttgaacaaat
     7141 tttctaagaa ttatcttcgt attttttgct caaaataaaa gtattttgtt attaaccgat
     7201 taatcaaaca aaaaatgatt accagttcat cgacatacac ataatacctc gataaaaaag
     7261 gggtgtcaat agttttgtaa aatttattta caacacccct tttttgaggt atactaattt
     7321 taggaggtgt ggtcaatatg ataaaacgtc caccaataaa ttatttagaa cgaaaaaaga
     7381 tactcggaac aaaaataaaa gctataagaa agagtaaaaa attaacacaa ccagcatttg
     7441 gtcttatgat taacaacggt caattaattg acaaaaagac tatctacgaa tgggagaagg
     7501 gaacctattt accaatacca gagcgattat cccgaattgc tgatttggga aatatgagta
     7561 tagaggagtt agtttgtggc aatgtagaag aatatatttt gggaattatt ctttatagag
     7621 atagcattgt actagatggt ataacatttc cagataaaaa cctgttccag catcttcgtc
     7681 aacagttccc accagtacac tctaatttag atacatggct ggatagatat tccaaattag
     7741 aaccagagat gcaagaattt attgctaaca agacttgtaa taaagttaaa aatgaaaaaa
     7801 ttagtctttt caatatctta aaaatagaag aattattcat caatgctatt gtagaagaat
     7861 ttgacaataa cattcttttc ctcactagca gtatagaaga actactagaa agaatggtag
     7921 atgaatggct acctattcaa ttgaaagaca tgtcttatcc cgaagaagct gtgagagaaa
     7981 ttactgataa tataaacaag ctagaacaaa cgatttcatc aattgggaaa aaatacacta
     8041 agaaaaaaat gaagggaggt gataccatct agtggtaagt actccttgta aactaagagg
     8101 agatgatttc atggcaaaaa tatcaaagta caaaaagaaa aacggtcaag tggcgtggat
     8161 gtataaagga cacattgcca ccgatccacg aactggtgaa aaaataaata ctacgagaag
     8221 aggttttagt agcaaacaag aagctcaaaa agattatgac gagtacagac atcaaatatt
     8281 atacggtgtt aaaaagaaag cacctgatat gacatttgaa gacctgtata atgaatggat
     8341 aactcatcag cgtaccagtg ttaaagcttc aacaatcgca atctcagtaa gatacgcaaa
     8401 taatcaaata cttccagcat ttggtaagct taaactatcg aatatctctg tcccatattg
     8461 tcaaaaagtg gtagatgaat ggcacagtaa atatgaaagt tacgattata tgagaaaaca
     8521 gactgcacaa attttacgct acggggttgc aatgcaatat attgacaata atcctatgga
     8581 aaaaacactt cttccacgaa aaaaagagta tgagaaaaat cgtaaatttt actcaaaaga
     8641 ggagcttaat aatttactgg atgcttttaa agattttggt aacatgaaac aatacgcctt
     8701 cttcagatta ttggcataca caggtatgag aaagagtgaa gtactcgctt tacagtggaa
     8761 agacatagac acgtttaata aagaactaca tgtcaataaa actcttgctg tagatgaatt
     8821 tggtaaagtt ataattcaat ctccgaaaac aagagcttct agacgagtta tctctttaga
     8881 tactgagact ctttctatcc tcaacaactg gaaattacag caaaaagaag agtatttaaa
     8941 acttggatac aatactagct ctaaagagca acatgttttt acaacagtta aaaacactct
     9001 atacattcca aacactgtta atgattggtt aagatatatt ttgaaaaaat ataacttgcc
     9061 tcgtattaca cctcatgggt ttagacatac acatgctagt ttattattag aagcaggaga
     9121 atctgtcaag gtagttcaac aacgattagg gcatgaaaat agtaaagtga cattagacat
     9181 ctatgcacat attacaaata atgcacctaa gaaaacaggt caagactttg ctgatatgat
     9241 ggctcatcag taaaagagct ggtcaaaatc tggtcatttc tagtatacag gcaaaacaaa
     9301 aaagctagaa cccttatata tcaagggttc tagctcctat aacaggttta cccaacactg
     9361 ccttccaatg actcttttgg gaatcagagg aaagaatcag gctttataga gatatttcat
     9421 ctaacaaatt actttagact gacagtatat atcagcaggt actgtcatcg ggaacgtagc
     9481 caatatcgta tccaaaacag caggtagaga agctatttga ggattcaagt tattctattt
     9541 caaccatgaa gttaagttca ttaaaaataa agatagttgg tatttcaata atttttgtat
     9601 agagttaatc actttattga tgctaattca tcttgattgg tattataatc gtattcaagt
     9661 tgcgtggcgt gcttttgcta gaaaatatat aactgttctt tataaagaaa tataaggatt
     9721 aaacattttt tatcatagag ttttacttat ctatagaatt atgtctgttc ctaattcagt
     9781 ttgatgaatt aactgataaa aaaatatcta ctatttaaag atacagggat aagtaagtaa
     9841 aaaaataaca tgtcattaga tagtagacag ttccaactct ttatttacct tttttgtatg
     9901 ctgcactgtc aatccaagtt cctaaattgt tgtatccatc atcacttata taatcatatt
     9961 ggccatcaat aatttcgtca aaccacaaat attctccatc tggtttttgc ccaattattt
    10021 taattactga ttgactagta gttgtcatct ggttaaaatc ttttatttta cctatattaa
    10081 cggccaaaat agcatttcct cgcttataac tctcctggat ttcatattta acatattctc
    10141 gatcaagagt ttctttacct atcagcacca cagtcactga tgttccaatt aattgattat
    10201 ctatccagtt ttttatagca atatctccat tacgtttaac tttctcaaat tcagccttat
    10261 ctacaaaacc agcttccttt gttcctcgca aagtccagct gtttctaact accattgctc
    10321 ttgttacatc tgcataatgg aaactaaaaa aaacccttct caccatatta atcctcctga
    10381 atactattta ttaaactgac aatttgttca acttttttat ctacttctcc ttcagtatct
    10441 aatttttcta gcgcttgaaa tttacttttt aaggaatcat caaaataatc actgaaattc
    10501 tcttgaatct tatcaaacaa aaccttactt gcacctttgg taaatccaat cggaactact
    10561 atattttcat tttgaacaga taattcaaat tcttcaatca ttccatctgc tgtaactatt
    10621 tcacctgatt caagtttgtt tccaaaaaca aaaatactaa tcccagactc tgcaataatg
    10681 ttttctcgat atcttctcca ctcatgaggc atatcaaggg gaagtggtct taaagaaagt
    10741 acgtcttgta tgttattttt tcttaaattt cttctctgct ttagaactcc tgaaacaata
    10801 ctattaccaa ttccaagtcc gtaacctgat actattctat aaccggattc agaaagccta
    10861 tatgctaatt tctcgacaaa ttttaatcct ttcgattcag atgtaaatgg agtataatca
    10921 acagcacttc ccgaaataaa aatagttttt ctcaaatact tttttctaat acttttcaaa
    10981 atatcagtaa tctcagaata atcatctact tcaacaacgt ttatcgaaaa tctggacaaa
    11041 tcattgattt gtagtcttct ttttgtcagt tcataattat atctctcttg atcaaaaaaa
    11101 tcctcagaat cgacaaaatt ttcctttaaa attatatggg attttagatt atctttttag
    11161 aagttcttga atgtcggtat agcccgtgtt tccgggcttt tccggcattt ttgatattgt
    11221 tagatactta caaatgttct tattacctct caccatttcc ccctcaaaag tagtaaatgg
    11281 agtagtaaaa ccggccttgt gtcaggctgc cagccgttcc atttctgccc ttgcggaatc
    11341 gaatgtggcg tgtgcataat agttcagcgt catggtgata ttggaatgtc ccataatgta
    11401 ctgcaaggct ttggggttca ttcccgcatt ggctaaccgg gtgcagaatg tatgacgcat
    11461 agcatggggc gtcgtcgttt tcggcaacgc ttcttcatgg ctcttgttgt acttcttcac
    11521 aagcctgcca aacatcccgc cataatctac cgccgtcatg ggatagccgt tctgtttgag
    11581 aaacaggaaa ttggcatacc cgtcaataat gaacggcttt gcacctttgc ggttttttat
    11641 cactcgctgg aacgcctgat acacttcctc attcatgggg atttttctga cgccgctttg
    11701 ggtcttgggt tcgtcaatat agtaaccgac gccggtattt ctcaaaagct ggtggctcac
    11761 gatgattacc cggttttcaa aatccaaatc tttgtccgtc agtccgcaca gttccgaaat
    11821 gcgaagccct gtccccagca gaataacgat tgcgtcataa tgcttttggt aaaccttatc
    11881 accttgaata aaggacagaa aactttcttc ctgtgctggt gtaagaggca cctttggttc
    11941 cgtatcgtcg tccagaacgt cactaagctg gaagtcaaac gggttttttc ggatgcaatc
    12001 gtcctgtatg gcggtgtaaa aagccgcttt cagggaacgc ttgtcgttat tgatggtctt
    12061 ataagaaagg cccttttctt tcatccgaag cgcccattcc tttgcgtcgg acagcttcac
    12121 actgtcaatc gggcagctcc ccagccgatc ttgttccaga atacgcatca gccgttcccg
    12181 gcccagtttg gtgttgtgct tcacattgcc ccggtgcctg atctgcttgg cgtagagctg
    12241 gcagacggtc attttcttgc cgatggtgtc tatcccgtcg tcaaggtctt tctggatttc
    12301 tttctccttt tcccggagtg aaatatcctc ccgtttacct gccggggtct tatccgtagg
    12361 cactaacttc catgagtaaa caaactgcgg ttttccaaag gtatcaacat atttgtaagc
    12421 atatcgtccg tcttttctct ggctctctcc agaccgcaaa acgcgatttt tgctgtctcg
    12481 tcttttttct gacatctcgt catgctcctt tccatgacgg aaagagccgc atatatgctt
    12541 ataaattatt ataacatatc tgcggccctt tttcactatt agattgtgtc caaagtgtca
    12601 attattttct caaactgctt gcgtttgatc tggatgcggt tgccattcat aatgacccag
    12661 ccagaggccg gattttcctc ggccagctta cgcaatttgt tttctccgat acggaaatat
    12721 ttagacgctt cctcaatcgt cagcgtgtat ttttcccaaa taggcacatc atggttcata
    12781 atgcagcccc ctttcacaaa ttcaaaggtt tgtgtgattt aggggcatag acggacggct
    12841 gctggcacag ctccacggga ctttcacccc cgcgtggttc tcacgcggcc ctacccattg
    12901 cctgcgacgc ttttaacgct cggactgtgg ctataaggga gtatcatagt cctgcctgta
    12961 cgtcgtcgcc cgcaagccgc cacgctcaca ttgcggcgtg gtgttcctcg ctccgctttt
    13021 cccgtaggga aaagtatcat ggcgcaccag ccgtccggct cggcacagac agaatgtgtc
    13081 cgtatgccct atgatgcgcc gccgttatct tgcgggcata tttatcaagg tgcgatcagg
    13141 ccaccgggaa aacaccgaaa cggggaaagg gtaagccgtt tcatgctgcc ggggccggtt
    13201 cgtcagttcg tgacgatagc gtggatgagc ttgatttcca gacggcgctt catggcctcg
    13261 tccagacaca catgcggata gccgttttcg tcatagagcg tccgggtaca cagcttgttc
    13321 atgtaaccgc tgtaatactg caaaacgcgc tctacggctc cggcatcccc agcgcgggcg
    13381 gcctcgatca ccgaaagggg caaaagctca atgcccttgt agttcgggtt cttcatccgc
    13441 gtctaacctc ccttcggcat caacgccttt agctgtttcc gcagctccga taaggtattt
    13501 gtcctgtgcc gctgaacggc actccgggac attcccacaa ggccgccgat ctcaccatct
    13561 gccatatcca gaacacagtg caggattaaa atactctgct ccatgctggg cagcgcggca
    13621 aaggcttcgg caacaagctc attgttgata tgtaggtcat agccatgcga cgaaaacgta
    13681 aagctgtcgc tggggtagtg atctactgta cagagcttgt ccaaatctgc ctgtgacaaa
    13741 gagcttagtg acacttcacg gtcacggcgg cgcttcattt cagccaagta gcttttggcc
    13801 tcgttacgca gtaccgtctt gcaaaaagca tcgaacatgc accgcgcttc atagtcgcgg
    13861 gggatagcat ccatcttctc accccctttc tgtgggggac ttaggtggtt ctctcccttt
    13921 ccgctaacaa gactttgaca aggccgccag ctacccgcta aatacctcct ttttgaaaat
    13981 ttctcaaaaa atttttttgg ggacagccgg gccgcaaaag acgacaaaaa tcgcccggca
    14041 ggtcgcaaac ctaccgggcg agaaaatgct ttgctatgct gctgatttac atggtatagt
    14101 acatactcat aaccggaata gccctgtg
//
LOCUS       DBBGSZ010000053        13940 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.055, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000053 DBBGSZ010000000
VERSION     DBBGSZ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13940
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.055"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            134..307
                     /locus_tag="ACIZE5_002404"
     CDS             134..307
                     /locus_tag="ACIZE5_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109517.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            947..1420
                     /locus_tag="ACIZE5_002405"
     CDS             947..1420
                     /locus_tag="ACIZE5_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HGC6109518.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1429..1656
                     /locus_tag="ACIZE5_002406"
     CDS             1429..1656
                     /locus_tag="ACIZE5_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6109519.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2292..2663
                     /locus_tag="ACIZE5_002407"
     CDS             2292..2663
                     /locus_tag="ACIZE5_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109520.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2919..3161)
                     /locus_tag="ACIZE5_002408"
     CDS             complement(2919..3161)
                     /locus_tag="ACIZE5_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGC6109521.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3193..4095)
                     /locus_tag="ACIZE5_002409"
     CDS             complement(3193..4095)
                     /locus_tag="ACIZE5_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGC6109522.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4108..4296)
                     /locus_tag="ACIZE5_002410"
     CDS             complement(4108..4296)
                     /locus_tag="ACIZE5_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HGC6109523.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4310..4873)
                     /gene="amaP"
                     /locus_tag="ACIZE5_002411"
     CDS             complement(4310..4873)
                     /gene="amaP"
                     /locus_tag="ACIZE5_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HGC6109524.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4911..5804)
                     /locus_tag="ACIZE5_002412"
     CDS             complement(4911..5804)
                     /locus_tag="ACIZE5_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HGC6109525.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5882..6805)
                     /locus_tag="ACIZE5_002413"
     CDS             complement(5882..6805)
                     /locus_tag="ACIZE5_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGC6109526.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6854..7204)
                     /locus_tag="ACIZE5_002414"
     CDS             complement(6854..7204)
                     /locus_tag="ACIZE5_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HGC6109527.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7237..8139)
                     /locus_tag="ACIZE5_002415"
     CDS             complement(7237..8139)
                     /locus_tag="ACIZE5_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HGC6109528.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8132..8989)
                     /locus_tag="ACIZE5_002416"
     CDS             complement(8132..8989)
                     /locus_tag="ACIZE5_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HGC6109529.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9323..10132
                     /locus_tag="ACIZE5_002417"
     CDS             9323..10132
                     /locus_tag="ACIZE5_002417"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC6109530.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10172..10669
                     /locus_tag="ACIZE5_002418"
     CDS             10172..10669
                     /locus_tag="ACIZE5_002418"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HGC6109531.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(11054..11127)
                     /locus_tag="ACIZE5_002419"
     tRNA            complement(11054..11127)
                     /locus_tag="ACIZE5_002419"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11091..11093),aa:Ile,seq:cat)
     gene            11314..11637
                     /locus_tag="ACIZE5_002420"
     CDS             11314..11637
                     /locus_tag="ACIZE5_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109532.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            11801..12055
                     /locus_tag="ACIZE5_002421"
     CDS             11801..12055
                     /locus_tag="ACIZE5_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109533.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            12125..12370
                     /locus_tag="ACIZE5_002422"
     CDS             12125..12370
                     /locus_tag="ACIZE5_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6109534.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            12446..12811
                     /locus_tag="ACIZE5_002423"
     CDS             12446..12811
                     /locus_tag="ACIZE5_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02328 family protein"
                     /protein_id="HGC6109535.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(12872..13435)
                     /locus_tag="ACIZE5_002424"
     CDS             complement(12872..13435)
                     /locus_tag="ACIZE5_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109536.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT         4087 a         2577 c         2303 g         4973 t
ORIGIN      
        1 ttcggagaat taaaaaatac aataaataac tttagttact ttaatgcgtt cttactttat
       61 ttttatatta tcatttttct tattcacttc tttggtttat actattctta taaataaaaa
      121 cgaggtatgt cctatgatga aaagattgta ctattcattg atcataacga ttggctattt
      181 gattgtatca aatctaggaa atatggtatt tggtatcagt aaagaattca gttggactac
      241 tacattatgg gaatctctat tctttttcat cttcgtattt ttgttacaaa attatcgaaa
      301 aaaataaaca tgtgccatct atctgttggc acatgtttta ggatttatgg tactttttat
      361 tcggcaatcc attttatttt tctacttctt cttaatacct ctaacacttt tgatttataa
      421 actaatccaa tgcatctact tgcgcttatt aagctatttc agctagatag taccacccca
      481 tgcgtcaatg cttgattttc cttttgtata acattgtata agcaataaag gacaaataag
      541 tggtgattac accaaaccat tgaataagaa aaattctgat acgtaaataa acatgaactt
      601 gaaaaaatta atgaatcggt tagctactac gtagttgtct tttttctcat acagttctgt
      661 taacttacac ttctcttcgc tagataataa aaaatcctcc aactgtattg tccaatataa
      721 tcccaggcat ctaaactagc attatagaag agacacacat agaatctaaa ataactggtt
      781 ttaaatgttt cttacaatca aaaaaagctg ttaaatgcac tccacacctt catactctat
      841 cattttttat aaacgatata tttttattgt ttttcgataa aaaatagttg ttttacaata
      901 attattctgc tatattttag ctatcaaaga taaaagaggg ataaaaatga aatttaaaac
      961 attgctatta aaatttgtcg ttttaggtat aagtgccgta tttattttgt tcggcgtact
     1021 tttttatact cagatcgcta caagcgaaaa aggattcaat tttgattggc agaccacatt
     1081 atttgtttct gtcatttact ttgcccttct cctagggatc gttattgctt atttcttatt
     1141 gaaactattg aaaaaaatcg aagataacca agctttttcc actcaaagct taaacatact
     1201 aaaaaaaatc gaacgaacca ttttgtttat tggtttcgcc ttttttggct tacttcctaa
     1261 atttatgaaa gtagcggatt tagacgatgc tccaggtttg atgttggtag gaatcgctgt
     1321 cgtattcatt ccttttgcag tatacacatt aacaagcgtg ctggaaaaac tgcttgaaca
     1381 tgcgatttta cttaagacag atcatgattt gacagtgtga ggtgcgacat ggcaattatc
     1441 gttaatttag atgtagtatt agctcaaaaa aaaatgagtg tgactgaatt gagtgagaaa
     1501 gtgggcatta cgatggcaaa catctctatt ctaaaaaatg gaaaagcaaa agccatccgt
     1561 ttttccactc tcgaaaaaat ctgccaagtt ttggagtgtc aaccaggtga tttgttgacc
     1621 tataaaaatg actcgaatac tataccagaa gaataaaata aagtagaaca aacagtaaat
     1681 aaaaaataat ctgaatgata gatgtgtgag acttttagaa gttatttacg tctattattc
     1741 agatttttta tttcgattga ataccgtttt atctataaat aagatatgta ctgactcata
     1801 caaagggggc cttttcttct ccatgtacta tcacttttcc tgatacaact ggtttcctgt
     1861 tacgttgtag ttggatctgc ttttagtata atactttatt cattccacca gactgatagc
     1921 agtttgagca gtctaaataa tcatgtagta ttacaggcca ttctgtttca taccttgaag
     1981 tgcttaaaac ttcagctaat ggcccattgt gttaactctt actccattct tttttagtaa
     2041 gctcccatat atactgtaaa gccttctata tattatgtca tgttgctttt taacatttac
     2101 tatgtagttt tgataaaatg atttgaataa cagtgatgga caattctttt ttatttttaa
     2161 cattattttg ataataatga ttatttattt aaaaatacat tagataacat ttgttacgac
     2221 acgaaaaagc ttcacaaaca aatatcgtta ttttaaaatg agggcgaact cacacaatta
     2281 ggaggaatag tatgccattt attgtttact tttttctttc attactcgtg atctatattc
     2341 cattaccaac atttttcctg ctcgtcaatc gtctagcaga gcaacatgat acgattgctg
     2401 ctcttacgaa actttgttta cttctatttg tttgtctaga ttactttacg agctattatt
     2461 ggctaaaaca gacaagagta aaaaagagat attatttctt ccttgtcttt ttcaatctct
     2521 ttgagtttct gatccattgc tttttacttc atcagtatca tacgatccat ttgtggatca
     2581 tctgggtttt caaagtggtc gtattatttt gtatgttcac ctttcctatc tcaagaaaat
     2641 ttagggaggc attgttttat taaagaagct tctctgtatc aataaagaca catttaagga
     2701 aaaactttta aaaatctaat tgggaatttg cccgcataaa taagaggctg tgacaaaagt
     2761 cttgtcacag cctcttattc cgtataaaca gtgttcaaaa gcttgcatct tcgataatat
     2821 gcccaaccaa atgaaaaata tgagaagcta tttttgtttg gctgttctta ttacttgatg
     2881 aagaacagct ttttcacgac ctctttttaa aagtcttttt acagttttcg agcaaagaat
     2941 gatacgatta gtactaaaat gatggcacca atcaatgatg gcacgattgc cattcctgca
     3001 atacttggtc cccaagaacc taataatgct tgaccaagtg ctgatccaac taaacctgct
     3061 acgacatttg caataatccc catcgaagaa cctttattcg tgattgctcc tgcaattgct
     3121 ccgataattc ctccgacgat aagtgaccaa ataaatccca tgtttcgttc ctcctaatgt
     3181 tttacttcct tattactgaa cccgtggttc tgtattttct tttacttttt gtgcgccgct
     3241 tccagctgct gattttactt tatctgtttg attcgaagca aattcaccgg tttttttcgc
     3301 tgcgtcagtt actttgtctt gcaccgtttc ttgatctttt tcaaattctt cttttgtttt
     3361 gatgtccact acgttagcgt tgacttcgat cacttctaaa tgtgtcatat tttttacttc
     3421 tttgccgatt acttcttgca tttcttcaaa gattttttcg atatctttgc catattccac
     3481 aatgacatcc atatcaactg ctacttgttt tttaccgact tctgtttcga tcccagccgt
     3541 tacattatct gtattcacaa gttttcctgc cacattagag aagaaaccac cgtttgcaga
     3601 taataaaccg tctacttgtt caattgcgat tccgatgatt ttttgcacaa ctttatcttc
     3661 ataattcagc tcaccgcgca ttgaatcttc ctgttcagaa tcatgctttc cttggttatt
     3721 tgtatgatca gaaccaagtt ttccttgtcc gtttgtgtgg tcagaactaa gtttttcttg
     3781 tgctttcgca tggtcagaag gatgtttttg ctcttccaca ggtttagaag gatcgattgc
     3841 atcatgttgt tctggaactt tagattctgg agttcctgga tgatgaggtg catgcttttc
     3901 tgcatcatgt ttcttctctt ctactccttg ttgaacgtta gggactactg gatctggatg
     3961 tgcagatact ggtgctgttt tgttcttttc atcgttcaca ccatttgatt ggtttggtgt
     4021 cgttgggtct ggatgtgcag acactggttt ttggttgttc attttattgt tattattttt
     4081 gttattgtta ttcatggatg tttcctccta agatttaaaa tagtgatcta agattttcgt
     4141 ttgtttcaga taaaaaccga tagcgacgcc gatcgctgcc atgatcaaga tcaataaggt
     4201 cttgaaaaag cccacggtga tccataaaac ggctaatatc aatccaagta ccccaaagat
     4261 gatagggagc ttgtatgtcg aaaatagttc tttcattttt ggtccccccc tattctactc
     4321 gtttgcggtc attgcttcgt ttagctggtt cttcaaagcc tgtgtatttc accgatactt
     4381 tcactggctc ttttgttccc aatatgtgtt gtacttcatt ttcgatttct ttcatcaatg
     4441 ttcctgtttt accaatgagt gctgaagttc gtttcaactc cccttttaca ttgacggcga
     4501 tcttgttttt cgttgctttg acatttactt ttggtgaatg gatgaattca tcttcatgca
     4561 agtgagaacg aaccattcct tcaattgctt ttttatccaa cgtcaactcc ccatcaccat
     4621 gtttcagtag aaagtttccg attgtttttg gataaaacag gaaaacaagt aacgtgataa
     4681 ttgtcaaaat agcaaatgca acggcaagcc aaaatacata ttgttgcacg tatgaattag
     4741 tgatggaaaa gaatcgaaac ttctctagct gaaaaggcaa tggataggtt gcacttaata
     4801 gtatcgcaaa caaaagcaca gatagcaaaa gtaatgttcc gatcactccg atcgttttta
     4861 cacctttatt cattttcgca cctcctcata ggggtgaaac gatcaacttc ttataagttg
     4921 atcgcttctc caccagttac tccgtaaatt tgggctgtaa cataacttgc tttattcgat
     4981 gctaagaaaa cataaactgg tgctaattct cctggctgac ctgcacgttc tagtaaactt
     5041 tgctgaccaa attcagggat cgaatcagaa ggttgtcctt cgtctagttg taatggtgtc
     5101 cagattggac caggtgctac accatttaca cggattcctt taggtgcaag ctgttttgct
     5161 aaaccgatcg taaagttagc gattgaagct tttgttgctg cgtaatctaa taaatgttcg
     5221 cttggattga atgcttgaac agaagttgtt gttacgattg ctcctcctgc tgggatatgc
     5281 ggaacagctt ctttcactaa agcaaacata gcgatgatgt ttatcataaa tgtgtctttg
     5341 acttgctcaa gtggtaactc agcaatagac tgacaagaaa tttgctgtcc tgcgtttagt
     5401 accatcgtat ctagcccgcc aagttcactc acggctttat ctatgatttc tttaggtgct
     5461 tgttcgtcac gaagatcaaa aggtagtaag acaatcttac gtcctgcatc tttcacgtat
     5521 tttgctactt cctctgcatc tttttcttct cctgggaaga attgaagagc gatatctgcc
     5581 ccttctctag caaatgcaat cgctgctgca cgaccgatcc ctgaatctcc accagtgatt
     5641 agtacacggc ggttttctag ttgattattg ccttcatagg attcttctcc acaatcagga
     5701 acaggaatca tattctgctg taaagctggt gtatcctgat cttgtttagg aaatttctcc
     5761 gtatggtaca agtttcgcgg gtcgattaat tttggttctg tcattgctgt attcctccta
     5821 gtttttaaat tgtattgcca aaacaaattt ctttgtttga tacctgtttt aaatagattc
     5881 tttaatttgt ataatctttc cggtataaat ggtaacctaa aactactgct gctatcaaag
     5941 agccaaagac tacgagtata aagcctagag cagaactttt acccggtaat cctcctgtat
     6001 tcattcccca aatccctgcg aacaacgccg gaacggaaat gattaatgca gctgaatcta
     6061 gatatttcat gatatgattt agattattgt ccatcatccc gttgaataga tcaccaatac
     6121 tctctaataa atctcgatag atctcgatca ttttttctgt ttgtcgctgt ctcaaatgga
     6181 catcatagag tagctgttca tcgtctaaac gtttgatgaa agtttcagaa ttccataatt
     6241 gatccattgt ttcccgttga tctcttaagg tatgatcgat atatacgatg tctctttcaa
     6301 gatctgcctg tttatacagt tcttcatttt ccgttgtttt acgagctgct ttatccaaag
     6361 cgtcaattcg ctttttcatc tctcttagtt ctttcacgta atgggtgtaa atatctaata
     6421 atgtatacgt gatgatcttt tcaaacgagt ttaaatgatt tccatgcttt gtcagcagcc
     6481 gatccacaaa ttcggttttt ctatcgatac aagtaatcaa gagattatcg gaaagtacaa
     6541 aagatattgg cgttaatttt ttttcgatac gattatctga ctgatctaga ttaatcacta
     6601 ccaaagaaaa tggatgctct agtttcgtct cataaaggcg ctccatccga gaaacttctt
     6661 ccggatattc ggttcctacg aaaatatcat caggaagctc gaattcttcg attgcttgct
     6721 caatctcttc gggctttgca ctatcaagta cgagccaatt atattttttt tcatctgttt
     6781 ctattacatt cttttcttca tccacaaagt agtatctcaa tgtatacctc ctttttggac
     6841 tttctcgaaa ctattagctg aagaagcagt tctttaattt gatattataa tcgagtactg
     6901 cgatttcatt ttctaatgaa aagctgtcaa gctgtttgtt gaagtccatg ttcaatcgtt
     6961 taccgaaata attttgctct aatttagatg tatagatgtc caataatgga tgctcgattt
     7021 tagtcgcata ttctccaaat tccgaaacaa aaggaatgat ttgaaaaaag ctgccttttg
     7081 caaaagcacc tttgtccctt agaaatggat cggaatcatt gataagcgcg agtgcgattt
     7141 ttgtattttc cccaaccttt tcaattaacg tctctactgc atttttagac attgtaattt
     7201 ccattcctac tccccctctt cagttgttgt cttctattat ttaacaacta catctgtttt
     7261 tggttgaact tttgcatatt ttggatattt agggaattta gctacacaac ggaaagccgt
     7321 catccctgca tatttttcgt aatatttctt cgttggccct tcaaaatcct tgctccacgg
     7381 tttcacatgt cctgaaaaat ggataatgta aggattgttg cgagtttctt cgtattcacg
     7441 ttcacctgct gctgttggat gtttttttgc ttttgccatg atatagcctt gtgcattcca
     7501 acgcggatga agtggtaacc aacggtcatg taagatagca tttaatgcat cttggtcatg
     7561 gaatcgtaat ttttctggat tatgttcgat gaaatctaat actttttgcg taatattttc
     7621 atctaaccat tttttcacat tgatcagcat caaacctgag ttgaaataac gcattgattt
     7681 agctgaaatt ttcatttttt ccagtcgttg atggaaccca gcgtcttcaa cagctgctac
     7741 gattgaatca ccgaagtcaa gacgccataa tttagagata tcttgtaaag cgatcatgtc
     7801 gcaatccata tataagatac gttcaacttc tgtgccgcgg aacaattccg gaatcgcaat
     7861 acgataataa gctgtttctg gaatacgatc gctgattacc acatttgtaa agaattcttt
     7921 attgattttc aagaattcca catctgagtt cattcgtgcg tttttcactg agaagcgtaa
     7981 aagctgttta ctttcaaaat cgatatcatc gtcaatcaca tagaaccgaa caaatttaga
     8041 cgggttgcaa ttatctaata ctgagacaaa taatgcagct aaatgtggta cgaattttgt
     8101 gttacaactt gcgactactg ctatttcttt tttattcatt gatctcgcct actttcgtta
     8161 gagtactgtg tgctaatttt tttaagtata aattggtata cggatgatct ttcaacgtat
     8221 tccaaggttt atcatgtcct gtaaagtgaa cgatcgaagg tttttcattt ccttctttat
     8281 actgacgttc atatttttca tttggtgctg gatgacgttc aaaaatcagc gaagtctgca
     8341 tgttccattt tggatgaagt tgttcccaat cttcataaag tacagcattc aaagcatctt
     8401 ggtcgtgata gatgattcga tcgccatttt cactgaggta atggatagtt ttttctgtaa
     8461 tttctttttt attccattga tcaatgtcaa tcaccatcac tcctgaattg aagtacaagt
     8521 catcggaatc gattcctaat ctttccaaag ctttcacttg gcctggatcg ataatagcgc
     8581 cgattgtttt tccatttaac ggctcatcat atagttttac gatatcgtct agtactaaca
     8641 catctgaatc taagtaaagg actttcttat aatcctcttt agctaataag tttggtaaag
     8701 aaattcttaa gtaagcggta gttgtgatat ggtcactgac taggaagtct tcgtagatat
     8761 ctttttccac tgtcaggaat tggatacttg cattacttga atatttattt accgtttctt
     8821 ccaatccttc tttactatat tctgatagac catcgtcaat cacataaaat tttatgcgtc
     8881 ttgttttatt gcaattttct aatgcagttg cgatcatcac gctcaagtaa ggagcataat
     8941 tttcgtctga agcagttacc acaggaacta cgccgtatct cttctccatc aaaatcactc
     9001 ctttttctaa tctttttcta acctgttcta catctagaat attcctcatt tggttttaaa
     9061 gcaaaatata tgctttgttt tcattgaata ttttaaaatt tttttatcac aaaacgcatc
     9121 ggtaagcgct aactattcgt ttttcatggc tttttattca aaggtattga ccaaaaacta
     9181 ctatatatag ccaccttttt cttaagaatg ttttttgaaa aaattcataa tgacaaagca
     9241 agttagtttc atttttttaa attctcattt aatcttaagg taacaggaaa atagatatgt
     9301 aaaaagaaag taggaagata aaatgaaact agcagcgatt gatttagacg gtaccttgct
     9361 tgatcgaaat ggaaagatac cagaagaaaa tatccaagca cttcggaaat ttgatgaaaa
     9421 tggcggaatc gtaaccgtcg ctaccggaag gaacagcatt tctgctaaag atattttttc
     9481 cgaattagga atcggtggct atttgatttc ttccaatggt tcactgattg ctgaaatgaa
     9541 ggatggaaaa atggcgaaag ttctcagacg ttcaaaaata gatagcgata cactgagaaa
     9601 agccttcttc tatgctcaag aagcgaaaat atccatcatt gctagccgag aaacccaaga
     9661 tgatcagctg acattcgatg aatcaaatct agtcaaagat gacccttatt atgaacattt
     9721 caatttacag aaccattctt ttgatcaaat tttaaatatg ttggaagatc cttctcttag
     9781 ctatcttaaa ttagcattaa cagataagag tgaagaaaaa ctacagaagc tacaaagaga
     9841 tctgcaagca gatggtatcc aatcagtatt ctctgatccg catttcttag aaatcacgcc
     9901 tacaggtatc actaaagctc attcacttgt ttttctggcg gattaccttg gaatcgaatc
     9961 gagtgacatc atggcttttg gcgatcaaga aaacgacatt gctatgttga attacagcgg
    10021 gttgagtatt gcgatgggga atgcacagcg acaagtaaaa gaaattgcaa accaagtaac
    10081 actgacgaat gaagaagctg gtgttgctta tattttaaaa aacttctatt aaaaagaata
    10141 aaatgacgat atgaatgtag gaggaaagaa aatgttagtt attattgata tgcaaaatca
    10201 tattcttgat ccaaacagcg aattttatat tccagagtca gatcaattgg cagaacgtat
    10261 tgctcaaaga ttagctaaag cacgccaaaa taatgaatat attctcttca cacgggatat
    10321 accagttgaa ctgaaggaca aagaagaaga acgagaagat ttgcaattga tccctcttct
    10381 ttctccacaa gaaaatgaac gagtgattaa aaagtattac tttacgattc cacctgaaac
    10441 tttagctgaa atccaggaaa ctttatttga aagcaaagaa gaacaaaaag agatcgaagt
    10501 agtcgggatt gaaacaaact tgtgtgtact ctctaatctg ataggcctgc agagtgcttt
    10561 tcctgaagca gacttttttg ttgatccaat gttagtctcc agtagaaaac acggagaatc
    10621 cgctttagag ctgttgaaag atttcaacgt ctctatcgtc gaatcataaa aatatctatc
    10681 ttcatttacg atatttaaca cacaataaaa aaagcacgca gaactgtttt agtcctacgt
    10741 gctttttcta tcaaagtaga ttggcttttt tatgacacag agtgaaacgg caggctcacg
    10801 acctctttct taaatggtgt tcaatcagct gaccctcggt attagcttaa caaacggcaa
    10861 aatatgagga actatttttc cgtttgttaa gctaatactc aggtcaaaac gctgatttca
    10921 caacctcttc cttaaacggt attcaaaagc ttgcatctgc agtaataaga acagccaagt
    10981 aaaaacataa gaagctgttt ttacttggct gttcttatta cttgatgcag ggcagctttt
    11041 tcacaacctc ttatgtacct tgtaggactc gaacctacga ccggacggtt atgagccgtc
    11101 tgctctaacc aactgagcta aaggtacatc ataaataaaa tttatttttg ttacttttca
    11161 actatagcac gaatgacaaa ctctcacaag tttcaaaata taagtaaaat aatattgtta
    11221 ttcttatttc ttttacttgt gtcataacta ttttgttact ttaattttta tttgcttatt
    11281 ttagaaaaaa tgttattctt ttatttattc tcaatgttag gagtgattat tttgccattt
    11341 attgcgattt tattcgattt agttgcggca gcagcttatt ttctccaatt aaattatcaa
    11401 acctcaggaa ttctgtttat tggaatgatt tttcaaggtg tgattaccct tttgcttctt
    11461 gtcatgatgc tcagctataa aggaaaaaga tatgcccgta ttcaaacaaa agtatttgtt
    11521 aaatatgttt ccattcgcta tgggatcatc attctttcct ttttagtgaa tgcgatcgtc
    11581 ctctttttat atgtattgaa ttacttagat atcaatccat tgattttttc tcgatagata
    11641 agacacattc agcggaacag ttcctgctta tcagcagaaa actgttctgc tttttcattt
    11701 ttcattgatc tattcttctt ttattttcct agcatttcat ttgtgatgta tgcaataaca
    11761 tgttatcttt tattatatga atcgttgagg agtccgttac atgattacgt tggtgagagt
    11821 tttgttttgg gtgcctgcgg tcgcactggt cgcaagtatt gtttatctta tgaattggaa
    11881 caaagaacgg ttttatttag ctattttgac tcttccggct atctacttta tgtggaaagt
    11941 ttttaattac aactactttg aacccgatag tgtttttata gaagaattat caggactggt
    12001 tttgtcttta ttgatcgtca ttctttattt gatacgttta aataaaaaac attgagtact
    12061 attgattgca tgtgtagctt tctatagtca ttataactat tctactataa tgaaaggtga
    12121 ttaaatgagt atcgaagaag ctattttact ggatacttta cgttgtcgtc tgaatttctt
    12181 aagaactggc cgatctttat ctcaagtagc tgtttctagc gcgttaagta ttcctttatt
    12241 caaatatcgt aagtacgaag aaggagaaga aattccaagc atcattgaat taatctatat
    12301 cgctgacttt tacgatattt ccgttgatta cctaattggt cgctcagaaa cagcaagcaa
    12361 actgaagtga ttttttccag ccttggtgct ggttttttca tttaacgtct aaggttaaca
    12421 atctatatat aaaggagaca tttctatgcg attatggcat gaaaaattga tttcaaagct
    12481 tcctcgtcaa cagcttttag gacaacatcg ggaatgctgt gcattaagag gaaatggctg
    12541 gggaaagaaa catgctactg tggattatgt ttttcactat tctccttata gattattcca
    12601 atatcatcag cttgtcatgg atgaaatgga aaaacgtggt tacagcccag caccagagtg
    12661 gaaaaatcct atgtatcgtg gcaaatcatg cgaagcattt tttgatttac ctactgtaga
    12721 gcgcaacgtg ccgatttatc cggaacacga tgaagtttat ctagcagaat gtttagcaaa
    12781 tttggagcaa aaaggaattt atcttaccta atataactag aaaagccttc tatctcctct
    12841 tacttcatta aaaagcttta accatcttag atcaagctaa aatgtcgtaa gttttagggt
    12901 tatcttcatc ctcacgtgca aaactaaaag cgtactctag ttttggttca tcgccaactt
    12961 ccctagacat aaatgaacat ctcctgacgt ggtttaaaag taccgcatct tcgacgtctg
    13021 tatacgatgc acagcacaga ttgcttcttt tgatctttct tttgattttt ctgttgcttc
    13081 ttctacacct tcttcgatta ctacatcgat gcttacaatt gcttctgcct aatattccca
    13141 tgcatcgtcg atttaagcct ctgtagtcac tgtgatcgtt tccacatttt aactcctctg
    13201 tcgtggcttc agttgatttt gtgatcagtt cagttgctaa gccagagtca gaacaacctg
    13261 ccattgctag cgttaatatt gatagtaaaa atagtttttt tatcataagg ttccccccct
    13321 gaaaatagac taaaataata acgctttctt tttttgtttt cagacgaaaa ttaataattt
    13381 ctaaatattc tttaaaaaag cttataacta ttatgccttt tttaatatat aacacagtta
    13441 tttttaaaaa taagaatgct aaatcactct acaataacgg cgaaagcaca aaaaataaaa
    13501 aaattattac gttattaaaa aaacagatga aagatcaggt tttattagat ctcattcttt
    13561 catcacttga agggatttaa tgaactactt tttcctcttt gtcgttttta tatattcgta
    13621 ttccttcaaa cagtaggata gcctctttca atgcttgata tttgaactgt ccgttactta
    13681 aaaatttaga tgtgccgccc tcttcctaga acatattctt ttttactttt tcattaattg
    13741 acagaccaat cgaacgaaac tgtaaatttc gataggataa tgattggtca aactcattca
    13801 ttttcaagac atctcgattc atattcaaga taggaatctt tttatcaaca tcactttatt
    13861 cgtattttcc tctaccataa aagcttcacg ctccacaaaa ttgttttata cactactatt
    13921 cagcccattc aacgaccaat
//
LOCUS       DBBGSZ010000054        13840 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.056, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000054 DBBGSZ010000000
VERSION     DBBGSZ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13840
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.056"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            82..1203
                     /locus_tag="ACIZE5_002425"
     CDS             82..1203
                     /locus_tag="ACIZE5_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HGC6109537.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            1210..4338
                     /locus_tag="ACIZE5_002426"
     CDS             1210..4338
                     /locus_tag="ACIZE5_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC6109538.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            4357..7551
                     /locus_tag="ACIZE5_002427"
     CDS             4357..7551
                     /locus_tag="ACIZE5_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HGC6109539.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(7697..8404)
                     /locus_tag="ACIZE5_002428"
     CDS             complement(7697..8404)
                     /locus_tag="ACIZE5_002428"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC6109540.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            9169..9567
                     /gene="spxA"
                     /locus_tag="ACIZE5_002429"
     CDS             9169..9567
                     /gene="spxA"
                     /locus_tag="ACIZE5_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SpxA"
                     /protein_id="HGC6109541.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            9899..10552
                     /locus_tag="ACIZE5_002430"
     CDS             9899..10552
                     /locus_tag="ACIZE5_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HGC6109542.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            10778..11776
                     /locus_tag="ACIZE5_002431"
     CDS             10778..11776
                     /locus_tag="ACIZE5_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA family protein"
                     /protein_id="HGC6109543.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            11952..13760
                     /gene="pepF"
                     /locus_tag="ACIZE5_002432"
     CDS             11952..13760
                     /gene="pepF"
                     /locus_tag="ACIZE5_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGC6109544.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT         4910 a         2286 c         2850 g         3794 t
ORIGIN      
        1 aatatgtaaa atagaagaca ggtgtcatgt aatggatcaa agtgttataa taattagaag
       61 gacatttttt gaggtgattg aatgcgtttt ttacatacag ccgattggca tatcggaaaa
      121 aaactacaag gttatgactt gattgaagac cagcgtcatg tactatcttc tatactagat
      181 atcgcgaaag aagaaaaagt agaggcaatc gtgattgccg gagacttata tgataggagt
      241 gtcccagctg ttgatgccgt agaattatac aatgaattga tggtcgattg gaatttaaag
      301 gaaaagatcc cgatttttgc tatatcagga aatcacgata gcagtacgag actttcagcg
      361 ggtacgccat ggttcagtta ttcgaactat tttttgcgaa cacagctagc agaagcattt
      421 gaaccagtcg agtttaaaaa cgtacaattt ttctttcttc cttactttga accaattgca
      481 gcgagattat attttgaaga tgacaatatc cgaacgatca agcaagcggt agccaaggtg
      541 atagataaaa tgcaggagct atttgattca gaaaaaaaac aagtattgat tagccatttt
      601 tttgtaatgg gaagtgtaaa atctgattcg gaaacgaaaa tcgaagtagg cgggttggat
      661 tcgatccctg gtgaactact tacaccgttt gattatgtag cactaggaca tttgcataat
      721 caagctgctt tgagacagga taatgctcgc tatagcggtt ccccattgaa attctcttta
      781 tctgagatca accaaaaaaa aggcgtatgg atcgttgacc tgacaacagg cctggagttg
      841 aattttaggg agatcgaacc cctgcatgat attgaagaaa taacagcgag tttcaaagaa
      901 ttgctggatc ctgcctttta tcagtccgtc aatcgggaga attacatcta tatctatctc
      961 actgatagaa cgatcatccc gaatatgatg aaccagcttc ggcaaatata tcctcgtatt
     1021 ttggggattg aacgggcaaa cggtcgagca gaacaaacaa agcgcaaacg aaaagtacta
     1081 gaaatgaaag atcctcaaaa attagcagaa gcatttttta gtgaaatgac ggaagagcag
     1141 ctaactgcaa accaagaaaa atggctcgga gaaacgttgc aagaaatcat ggaaatggaa
     1201 tgatcaagaa tgaaaccgaa aaaattacaa cttaaaaatt ttggtccttt tatcaatgag
     1261 accgtagatt tttcacgttt gacagaagca ccgctttttt tgatcagcgg gaagacagga
     1321 gctggcaaaa cgacgatttt tgatgggatc accttcgcac tttttggtga aacttccgga
     1381 agacttcgct ctggaaaaga gatgcgttct ttgtttgcta caccagacga agaaacaagc
     1441 gtgacttttt cttttgaaca tcagcagatg agctatgaaa tcgaacgaaa accagaacaa
     1501 gttttagcaa aacgaaaagg aaacggaaca aaaaaacagg cagccaaagt aacgttgacc
     1561 atttttgatg ggaaaggaaa agaaataaaa caaatcacaa aacgtacaga agcagatcag
     1621 ttgatcagag aactgatgaa tctcgatgcg aaacagtttt ctcaaatcgt tttactaccc
     1681 caaggagaat tccgtaattt tttggtttca tcaagcagtg ataaagagac tgttttacgt
     1741 catttattcg gtactcaatt tttccaacag ttcaatgagc gattaaaaga aaaagcaaaa
     1801 caacagcaac aaaaattgga tcatttagag caagagctgc atcttctgca aaaaaggttt
     1861 gttttagtca aagaagagga accagcagca gggtttgaag ccgttttagc ccaatggaca
     1921 aaccatcagg caatactcga aaaacaaatc acggaagaaa aagaagctct aacggaactt
     1981 caggaaaaac aaaagcaact agaaaattcc tactatcgtt ttgaaagctt gaaaaaaagt
     2041 tatgaagaaa aaacgatatt aataaacaag caaaaggaat tagctgctca aaaagacgaa
     2101 atagaggaaa agaaacgatg gattgggtat tatgaattta cgcaacgatt agtcgaacca
     2161 atccagcgcc tacaagaaat aaaagttgaa aaaatagaac tgtcacaaaa aagtagtgag
     2221 caaacaaaga aactagcgat gactacgcag aattatgaag agtggcaaaa aaatgaagca
     2281 aaccgcgtac gccgacaaac aaaaatcaaa gaagctgctc aaaaactgca aaacaaacag
     2341 atgatggtgc caattgtcga atccttacgt agtaaaaaac aagacgcaga acaattaaca
     2401 atttcattgg ataaagaaga attgaatgcc gagaagctgt atcaaaatct cgctatctat
     2461 caggaaagaa ctcgaattct tcaagaaaat ttactggatc aggaaaaact gcaagaagat
     2521 cgtcttgctt ttggacagtt aaaatatcta gatgaaaagc agcaagaaat agaaaaacaa
     2581 aaagcaaaag acactgggtc gctcgcacag ataagagaag aactcaaaaa agcaactgaa
     2641 gaaataacaa aaaatagtca gctattgaaa gaacagacag aacaagcaga acagctgaaa
     2701 agccaatggg caaagcagca aattgctcgt cttcagcttt ttttgcgtcc aggggagcca
     2761 tgtcttgttt gtggatcaac ggaacacccc atacaacaat taaaacacga acagccaaat
     2821 aaggaagata tcttaaaagt agaacaacaa ctggcagaag ctgagtctgc tgtagaaaga
     2881 actcagcaaa tcattgccaa aagtgaagca catgaaaata atcttcaaca acaattatca
     2941 gatttagaac aaaaaatcat ggcaacgaat atacaattgg ctgaacaaga agaacacttg
     3001 caacaggctt tgaaaaaggc atttcctgag ataacagaac aaaaaacaaa aacaactctt
     3061 gtagtaatcg aacaatcttt agatagacga aaaagcaaga tggccaatgc aagaatagag
     3121 ctggaagaaa taagacaaca agcagaaaag ctcgaacaac aattagctgt ctacaaacag
     3181 cagcagacag aaaaaaataa tcagctccag caactgcaag gagaaatcaa aagtttagaa
     3241 caacaattgc aagatacgga tagtaactgt ttagaagagg agatacgacg acttgaaaaa
     3301 cagttagaag aagactcgaa tcaactagct gttgagcaga aagcaggagt gcaattgttg
     3361 caagatcttc atacgcttcg gacacagctt gatcttcaac atgaacaaat agaaaaaata
     3421 gatgaaaaaa tagaaaagga acaagaaaga atagctaaaa agttagaaag ccagtcgtat
     3481 ttttcaacaa ttgaagaaat ctgtgcattt gcacaacagc aagcacaata taaagaaaac
     3541 caacgtacag ttacttctta tcatgaagag caattagtga cagctgaccg gctgcgtcaa
     3601 ttagaaaata tccagctaac tgagacattc ccagatacag aagagatcag ccaacagtta
     3661 gaagaaataa gacgtatgat cgaaataaag caagaaaaga tatacggttt acaagaacaa
     3721 aaaattagta atcaaaaaat ctacgatgaa tgtctttcga tttatcacac aagccagacg
     3781 aaattagatg agcttacgca attacagcag ctttcgcaaa cattcaacgg agaaaatcct
     3841 aagaagacta gtttggaacg gtatgtgctt caggtttatc ttcaagaagt gttacaagta
     3901 gcaaatgatc atctccaacg tttaacgaaa aatcgttatc aatttgagct agcggatacc
     3961 attggcagtt atcgagggaa aaccggatta gaaatcaata tctatgatga tcaggcaggt
     4021 atgtctcgaa gtgcgcatac cctgtctggc ggtgagagtt ttattgcagc actttcttta
     4081 gcattagctc ttgccgatgt gatccagaca caagctggtg gtgtagcaat cgatgcattg
     4141 tttattgatg aaggatttgg gtcattagat gaagaagctt tggaaatggc aatggaagct
     4201 ttagaaacga tcgaaagtga aggaagaatg atcggcatca ttagtcatgt aagagaattg
     4261 aaagaacgag tattacaaca aataagaatt gatacagaag gtagcggaca aagcaaaata
     4321 cgctatcaac ttggataaaa agggagattg gtaactatga aatggagtat tccagaaaaa
     4381 gtcattgcac gtggacgtca atacttgcaa gaaggccgag tgttatcggt tgtccctgac
     4441 caagaagaaa acgtgtggca tgcagaagtc ttgggcagtg aattgtatat ggttgatttg
     4501 gatggtacag caaaagagat agattactgc caatgtccct attgggagga acataaatat
     4561 tgtaagcata cagttgctgt ggaactttat ttacggtcga aaaatctatc tcgtatcatg
     4621 aaaaaagacc agccaatgct agaaccggta aaagcaacaa gtgagggaga aatcattgca
     4681 aaaggttttt ctcgtctaaa aacacaaaac aatcctcaag cggtgcaacc tttgattatt
     4741 gaataccaag tagaaacgat tgagactaat cagtatcacc cagagctttc tattttggca
     4801 ctttacttgc gtatcggttc attggcatca ccgaaaaaaa catatatcgt aaaaaacatc
     4861 tatgattttt tacaagctta cacagaaaaa gaaacttaca ctgttaataa acagtaccag
     4921 tttcgtctag ataaacgggc gtttcaaaaa gaagatcaaa aaatactcac gcatcttgca
     4981 ggaagtgctc agacgcatca attattaggt acgaacggct tacaagtcaa aggaaaacta
     5041 gataaaagat atctgcttct cccagtagaa caagcccgct tcctgttaga gcagatgaat
     5101 cagactacac gtttgcatct gcagataaat gaacaaaacg atcaaggaat acaattttcc
     5161 gatcaaaaca aacctttatc attcaaagtg gaaaaatttg gagaagatta tttgctgcaa
     5221 gcattgaatg attttgattt tttctttatg cattatcagt ggggagttat ccaagggaca
     5281 ttttattctc tgacgaaata tcaacaaacg gtttatcaaa cttggaaaca attgattcgc
     5341 cgattggaga aaccagaagt agtgttcaag aaaaaagaat taccgtcttt gtttaaagag
     5401 attatccctc tgctgtcaga gatcggcgac gtagctattg cccctgcagt agaagaggaa
     5461 gtagcagata tccccgtcga atttattttc tttttccgaa aagcaaaagg aaaaatccaa
     5521 gctcgagtcg atttcgtcta tggcgaagtc atctattcga ctgacccgaa gcatgaggtc
     5581 tcgacagaac aggcttttca ggtgttacgt gacacagtag aagagaaacg agtacttgat
     5641 ctattcagaa tgtatcgcta ccagaaaaat gaaactggtt atgaacgtcc attgccaagc
     5701 ggggaagaac tatatgcctt tttccgcaca gaactatctg tcttccgtca gtttggtgaa
     5761 gtcagacttg gaagaaaatt gcgagagttg tatttagatg cgcataaaca tcaaccgaaa
     5821 atcgaagtaa ccgagaccgg ttcatggctc gatattcgat tcgatgtgac agggatagag
     5881 gagcaagaaa tcgatcatgt cctgcaaagc ttgctgagaa atgatgcttt ttatacatta
     5941 gaaaatggtc aggttctttc ttttgattca gaagaatttc aacaaacaag ccaagtgttg
     6001 caacaattac gggaatcgat acgtacagaa gaaggaacga tccatgtacc taaaaatcaa
     6061 ggattgatca ttcaaaatca attggaaaaa agcaatgcta cttttagtga atcgttccaa
     6121 acgatggtac aagatctcat tcatccagaa agataccagg cacagcttcc caaaggattg
     6181 aatgcaacga tgagagatta tcaaaagcaa ggttttcgat ggttgaagat gttaggtcat
     6241 tatcagtttg gcggtatttt agccgatgaa atgggacttg ggaaaacact acagacaatt
     6301 gcctttttac tttcggaaaa agaagaacgg aaaagcttct ctgctttgat cgtagcgcct
     6361 gcgagcttaa tttacaactg gcaggcagag gtgagaaaat tcgccccttc tttaagtatc
     6421 caagtaatca atgggaataa aaaagaacgt gaagaattac tggctaaaga cacagatatc
     6481 cgagtgactt cttatgccag cttaagacag gatctagcta attatcagtc gcaaaaaatt
     6541 gattatttga ttcttgatga ggcacaaatg gtcaaaaata gcagtacgaa aactgcacaa
     6601 gcattgagag aattagctgt acctcagcgg tttgcactga gtgggacacc aatcgagaat
     6661 aatttagaag aattgtggtc attgtttgca acgattatgc caggattttt cccgactaaa
     6721 acaaaattca gggaacttgc cgcagaagaa attgcgcaaa tgattcgacc gtttatttta
     6781 cggcgagata aacaaactgt gttgaaagac ttgccggaaa aaacagagat gaatctatat
     6841 tctgcactta cagaagaaca aaaaactgtt tatttagctt acttgcgtca aatgcgtgaa
     6901 gaaatcacat caatggattc tgaagcattc aagaaaaacc ggatcgggat acttgctggt
     6961 ctgacaagac tgcgacaaat ttgctgcgat cctcgtctgt ttattgaaga ttaccaaggc
     7021 ggttccggca agctcgaaca agtaaaagat ctactggtag ctgccaaaga gaacaaacga
     7081 agagttttgc tgttttctca atttacaggg atgctgacta tcttgcaaga agagttagcc
     7141 gagctaggga tctcgacatt ttatttaaga ggcagtacga aaccacaaga tcggttaagt
     7201 atggtagacg catttaatgc tggcgaaaaa gatgtttttc tgatttcctt aaaggctggg
     7261 ggaactggat tgaatctcac gggagcagat acggtcatct tgtatgacct ttggtggaat
     7321 cctgccattg aagaacaagc tgctggacgt gcacatcgga tcggacaaaa aaatgtggta
     7381 gaagtgtggc gtatgatctc tgaaggaacg attgaggaac gcatggattc actccagcaa
     7441 gaaaaacgcg aactgttcca aaaagtgatc caaggtaatg aagaacagtt gacgaaactg
     7501 actgaagaag acatccgcat gattttaagt gtaggagaaa tcgaggagta agagactcga
     7561 aaaagcgttc agtaatgggt aagaaagcct ttctaaagaa gcgattgttt atttgattta
     7621 aaaaatagca aggaggctgg gattccattt tatcccagct tccttgctat cattttttta
     7681 tttctatttt taaaggttat acaaagattg tcttcattgt ctctaacagc tgatcaaaag
     7741 aagaaatctc gatatcgcaa attggagtct gttcaatttt gcgttctcga tggttgaacc
     7801 aaagcgcttg ccagttagca ctttttgcac ctagaacatc attgtcgtaa ttatcgccaa
     7861 cgtataaggt ctcttctgga agcatatgaa attctttctc agctagctga aaaatctctt
     7921 tttctggttt ttggaaacct gttgcttgag aaatgagcat attgcgggaa ggaatccaat
     7981 tgttcaattg aagttgcttc agtttttttg tctgatggtc agtcggccca tttgtgataa
     8041 ttcctaatgg gacattcttt tccttcaaga aatcgagggt ttttttgacc tcctcatgca
     8101 agcagatatt atcaagttct tcctcgtaaa ttttttgaaa taagaggcca tcttcttccg
     8161 taatatgagg gtagtctaaa tcttttagtg attggctgat ccgatgtgct cgcatatatt
     8221 ctagtgtcca atctcctgcc attacttttg ggaagttttc atcactatga tggcggaacc
     8281 ggatatatag tggatgcata tctgcatctg aaacaagcgg aacgactctt ttgaccgcgt
     8341 ttcgaaatgg ctgctgctga tcatacatcg tatcatcaac atcaaacaca actgatttaa
     8401 tcaaaatttt acacgccttt cggttttcat tgattttttc acaaatcctt gactattgta
     8461 acagaaaaaa ttgtctaaaa aagctgataa ataaaggttt ttcttactat atttctattt
     8521 ccttgacaga ataaggtttt tatatttcag tttttttcac taaaaatcgt gaaacacgtc
     8581 aataagtttg atgaacaaat taatcattat ggtagaagtc gattgattta ttttaatgca
     8641 atctctgtgg aattttcgaa agatttattt ttttaataca gtctcaatat aactattcaa
     8701 acataaaata acgttatttg atttatttgt ttatagtaaa ttttatttag taatcattgc
     8761 tttaaaatac tacgcttata taacagagaa aataagcgtt ataataaaga acagtattat
     8821 ttaaaatgac agaaaacatt actattaaag aaataaaaaa cataaaaaat cttaagaaat
     8881 cggtttcatt tagcttttga gataaaataa tagtacagtt ttatacgctg tttcatatgt
     8941 ttagaaaatt tgaattagat ttgaaaactc taatttttaa atgataaaaa aagcgagaat
     9001 gctggtttta ctgtatatta accttagata actttcattt ttttaaaaaa attatgaaaa
     9061 aaaggtagct atttaaaagt tgattatgta taatagaaac agatgggaga ttattatgat
     9121 cttctgttac aaaaaagtga ttcttatcac gaaaaggagt ggtgcacgtt gttaacatta
     9181 tatacttccc caagttgtac ttcctgcaga aaggctcgtg cgtggttgca agaacatcag
     9241 attccatttg ttgaacgtaa tattttttca gaaccattga acagttctga attaaaagcg
     9301 attttacaaa tgacagaaga cggaacagaa gaaatcatct cgacacgttc caaagtattc
     9361 caaaaactga acatggattt agatgatctg ccgttacaag aattattgga acttgtgcaa
     9421 aacaatcctg gattgcttcg ccgtccaatc atgattgatg ataaacgtct gcaagttggt
     9481 tttaatgaag atgaaattcg tcggttccta ccgcgcgatg tacgacaatt agaattacgt
     9541 caagcacaat tgatggctgg attatagaag gataatacga aacttggaaa agactattac
     9601 aaagatagtt tttccaagtt tttttgtttt tacaaaaagt attcttgatt agatgtataa
     9661 aaaggtagta gaagatgatg attgcacgaa aaatagagag ggaaaattag ctgaaaagtc
     9721 ggctatatag tattcgtctg ccaaaaatgt tatagttaaa taagatagct tgaaaggttg
     9781 aaaaatccgc tggttttatt aaattcgctt aacagcgaga ttttttttct ttacatttaa
     9841 gctgatttcg ctacaatgaa tctatattaa acattgtggc aaagtgaggt gtagcaaaat
     9901 ggaaatggaa catattaatg aaaatacgat ccgtgtacta attggtcatg aagatttaga
     9961 ggaacggggc gtttcatttt tggatttact tggcaatcac aaagaaatcg aaaatttctt
    10021 ttatagtatt ttggaagaag ttgatatcga agaggagttc cgaggaagcg aagctgtcac
    10081 tttccaagtt ttgccaaaag gagacggatt agaactgttt atcagtaaaa atcttccgga
    10141 tgaagaaatt tctcaatcag aagattctac tgttgattca gaagatgtga gtgactttct
    10201 tcgtcagcag attattggca gcgatccgga ggaagaatta tctggaagcg ccctagaaga
    10261 acaggaaaga caagcaactt ttgcttttga agattttgaa caagtgatcc aacttgcaac
    10321 agatgtcgaa ctagagtctg cttggactga tttgtattta ttcgaagagc gctattacct
    10381 agtcgttcac ttctggatgg aaaatctcaa ccaagcggat gtagagaatc agattgctcg
    10441 aattttggag tttgctgaaa agagcgatcg tacaccagaa acattgaatg aatatggaca
    10501 atgtctgatg gcgcgtaatg ctatcgagcg aacgaaattt tattttgtat aaatcagcat
    10561 tatagtaaga gactgtgaca aaaattgtgt cgcagtcttt ttttcgtata aatgtgttca
    10621 aaagcttgca tctgcggtaa caagcccaac caaacgaaaa atattgggaa ctatttttgt
    10681 ttagctgttc ttattacttg atgcagaata gctttttcac gccctctttt ttcgtgtaaa
    10741 taaattctta gacgtaaata agttcagagg gagaaaaatg ctgcttgcaa tgaatgaata
    10801 taataagtgc tgttttgcta aacatgcaga aaaaggaaag aaatattatt gtcgtggctg
    10861 tcgaaaaaga gtgattttga aaaagggaaa gaaaaaatgt gctcattttg cccatcaaaa
    10921 atcagataac tgttcggtct ttagtgaaag agaatcaaaa gagcacttac agttaaagga
    10981 atgcttcatg gattggctgg gacagtcagt agaaccagta tttttggaag cctatttgcc
    11041 gaggttgcgg caaaggccgg atattttgtt ggcgaatcta gcaatagaaa tccaatgttc
    11101 tagactgtct caccagagat ttattgaaag aacccaaaat tatttgaata acagttacca
    11161 agtatggtgg atacttggta attcttttct tggacaatcg caattctcat tgatagaaaa
    11221 aagttgctgc tactataata gaaaaagagg agtgcattgc tggaaagctg atctcaagaa
    11281 acaaaagctt tatttgtatc atcatattac agagactgta tcagggcata tttccttttg
    11341 cagtagctgc tggacttttt ctagtaggga ccttaaagaa atattcacta gtaacgaaat
    11401 taaaatgaac caaatgaaaa aaatagaaaa agtgagtgaa gatgggaaga aatggctgac
    11461 acgccaactt attcacaagc aaaagaatac agtatccata caagaacaat gctacttgcg
    11521 tcataaacat cttttgcatc tatcatcgtg gatctatcaa aaaagtcggt ttttctttta
    11581 tttacaagaa caggtttttc tttatcgaat gttgtacgaa gaagccttgg aaaaccagaa
    11641 agttcctgat ttcaactcat ggctttgcca aataaaagaa cataaaaggg aatggctttt
    11701 tcctatgatt gatgaagaga tggtctatca gcagtttttt aacgaatgca tacacttgtc
    11761 ttctttgaaa aaatagtaag tataaaaata ggctaggaat cggttttcta tgtaaaacaa
    11821 gatttagtta tgctaaaatt gatggaagca gacacatgaa tgagtagaaa agttagatgc
    11881 tgtgacatgt ggatgttaga ctatgatcta ttttgataga tagagctaag ggaagaaaag
    11941 gagtggattt catggaagta aagcagttgc caaaacgaga agaattgcct gaaaatttaa
    12001 cttgggactt gaccaagatc ttttcaagcg accaagagtt tgatgagaaa tatttggaat
    12061 tatcagaaga gttaaaacaa tctgaaaaac acaaaggaac acttgatcaa ggcgcttctc
    12121 aatttttaaa tgcgattgaa ttcgtattga gggtttatcg ccaaactgaa gtcatttatg
    12181 tatatgcgca ccttaaaaac gatcaagaca ctggaaatac agattaccaa gcgctttatg
    12241 caagagcaag cagtctgttt tcgaaagtta gtgaagccgt ttcctggttt gaaccagaaa
    12301 tattgcaatt gtcagatgac cagatttggc aatatttcaa agaagaacca aaattggaag
    12361 tctatcgcca ttatatccag caaatagtag ataatcgagc ccatgtctta tctgctgagc
    12421 aggaatctct tcttgctgga gcaggtgaaa tctttgatgc ttcaagtgat acatttgctg
    12481 ttttgaataa tgcagatcta gtttttccaa cgattgaagg agaaaatggt gaaatagtcc
    12541 aattatctca tggcgtgtat ggtcagttgc tagaaagcac ggatcgaagg gtgcgcgaag
    12601 cagcatttaa ggggttgtac agtgtttacg aacaatttag aaatacattt gcttctactt
    12661 taggcacaca tataaaagga cataatttta aagcgaaagt ccgtaattac agctctgcca
    12721 gagaagcgtc tttgagcaat aatcatattc ctgaaagtgt atacgatact ttggtagacg
    12781 tggtaaacaa gcatttgcct ttgttacatc gatacatgga attacggaaa cgtttattag
    12841 aagtggaaaa actgcacatg tatgatcttt atacaccggt cttaggggaa gctccaatta
    12901 cctttacgta cgaagaagca aaagaaaaag ctttagaagc actgaaacca atgggtgaag
    12961 aatacatggc catcgtagaa aaagcattct ctgaacgttg gatcgatgtt gtcgaaaata
    13021 aagggaaacg aagcggtgct tattcttcgg gaagctatga cacaaatcca tatattttat
    13081 tgaattggca tgatacgctg gatcagctat ttacgcttgt ccacgaaatg ggacatagtg
    13141 ttcatagtta tttcactcgt tcgaaccagc cttatgtgta cggcgactac tccatctttt
    13201 tagcagaaat tgcttcgaca acgaatgaaa atatcctaac ggagtattta ttggaaacag
    13261 aaaaagaccc tcgtgtacgg gcttatgtac tcaaccatta cttggatggg tttaaaggaa
    13321 cagttttccg ccagacacaa ttcgctgaat tcgagcattt catgcatacg gaagatgaaa
    13381 aaggtgtgcc attgactagt gaatacctaa gtgatagtta tggtaaattg aatgcaaaat
    13441 attatggtcc agcagtcgaa gaagacccag aaattaaatt cgaatggtca cggataccgc
    13501 atttttatta taattactat gttttccaat actcgactgg cttttctgct gcttcagcac
    13561 tggcgaagaa aatactaaac caggaaccag aggcactaga gaactacttg gcttacctaa
    13621 aagcaggtaa cagcgattat cctgtggaag taatgaaaaa agcaggagtt gatatgacac
    13681 aggctgcata tattgaagat gcaatgtcga tgtttgaaca acgtctaaat gaattagaag
    13741 aattgatcga tcgtttataa ggctttctat ttttgatttt ctcgaataga aacgaaaaaa
    13801 atacgtcggc tctcttgtaa gggagtcgac gtattttttt
//
LOCUS       DBBGSZ010000055        13591 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.057, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000055 DBBGSZ010000000
VERSION     DBBGSZ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13591
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.057"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            312..482
                     /locus_tag="ACIZE5_002433"
     CDS             312..482
                     /locus_tag="ACIZE5_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109545.1"
                     /translation="MKKFIYRVLENDEVVAIFNEQQYAQDFIAYEKTISDKQFEIEKV
                     DIADWLLQPREF"
     gene            496..1098
                     /locus_tag="ACIZE5_002434"
     CDS             496..1098
                     /locus_tag="ACIZE5_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6109546.1"
                     /translation="MAKIGYARVSSKEQNLDRQLKALEGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVVVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINNLVIELYKYQAESERKRIKERQAQGIEIAKKKGKFKGRQPKFKENDPRLQHAF
                     DLFLNGCSDKEVEEQTGINRRTFRRYRSRYNVTVDQRKKQ"
     gene            1114..1791
                     /locus_tag="ACIZE5_002435"
                     /pseudo
     CDS             1114..1791
                     /locus_tag="ACIZE5_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            2102..2599
                     /locus_tag="ACIZE5_002436"
     CDS             2102..2599
                     /locus_tag="ACIZE5_002436"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HGC6109547.1"
                     /translation="MLFLRDGEIKATLTTMMNKLAFSHKLILEPLFKSVSQIDEESDR
                     ERMDAIDKLMEQLLEERNTLIALMSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTN
                     SASGVLRANEIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLK
                     EKVVR"
     gene            2600..3016
                     /locus_tag="ACIZE5_002437"
     CDS             2600..3016
                     /locus_tag="ACIZE5_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HGC6109548.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            3036..4580
                     /locus_tag="ACIZE5_002438"
     CDS             3036..4580
                     /locus_tag="ACIZE5_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6109549.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            4723..4947
                     /locus_tag="ACIZE5_002439"
     CDS             4723..4947
                     /locus_tag="ACIZE5_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6109550.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            4962..5831
                     /locus_tag="ACIZE5_002440"
     CDS             4962..5831
                     /locus_tag="ACIZE5_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HGC6109551.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            5812..6546
                     /locus_tag="ACIZE5_002441"
     CDS             5812..6546
                     /locus_tag="ACIZE5_002441"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC6109552.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            6579..7487
                     /locus_tag="ACIZE5_002442"
     CDS             6579..7487
                     /locus_tag="ACIZE5_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HGC6109553.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            7484..8026
                     /gene="sat4"
                     /locus_tag="ACIZE5_002443"
     CDS             7484..8026
                     /gene="sat4"
                     /locus_tag="ACIZE5_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HGC6109554.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            8119..8913
                     /locus_tag="ACIZE5_002444"
                     /note="aph(3')-IIIa"
     CDS             8119..8913
                     /locus_tag="ACIZE5_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HGC6109555.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            9189..9320
                     /locus_tag="ACIZE5_002445"
                     /pseudo
     CDS             9189..9320
                     /locus_tag="ACIZE5_002445"
                     /inference="COORDINATES: protein motif:HMM:NF024804.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
     gene            9396..9889
                     /locus_tag="ACIZE5_002446"
                     /pseudo
     CDS             9396..9889
                     /locus_tag="ACIZE5_002446"
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            10059..10955
                     /locus_tag="ACIZE5_002447"
     CDS             10059..10955
                     /locus_tag="ACIZE5_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC6109556.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     GNLASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMIERIIQLENEKE"
     gene            11054..11263
                     /locus_tag="ACIZE5_002448"
     CDS             11054..11263
                     /locus_tag="ACIZE5_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HGC6109557.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            11280..11552
                     /locus_tag="ACIZE5_002449"
     CDS             11280..11552
                     /locus_tag="ACIZE5_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HGC6109558.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            11554..12417
                     /locus_tag="ACIZE5_002450"
     CDS             11554..12417
                     /locus_tag="ACIZE5_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HGC6109559.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(12680..13417)
                     /gene="erm(B)"
                     /locus_tag="ACIZE5_002451"
     CDS             complement(12680..13417)
                     /gene="erm(B)"
                     /locus_tag="ACIZE5_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HGC6109560.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT         4818 a         2106 c         2842 g         3825 t
ORIGIN      
        1 tatgatacgt gtttgttttt ctgtgctgtt tagtgaatga ttagcagaaa tatagagagt
       61 aagattttaa ttaattatta gggggagaag gagagagtag cccgaaaact tttagttggc
      121 ttggactgaa cgaagtgagg gaaaggctac taaaacgtcg aggggcagtg agagcgaagc
      181 gaacacttga tcttttaagt tgctatcttt ttaaggtcaa tagagtatac ttatttgtcc
      241 taatatggtt ttagcagtat aattgacttg gtgaataggt catttaagtt gggcataata
      301 ggaggagtaa aatgaaaaaa tttatttatc gagttttaga aaatgacgaa gtggtggcta
      361 tttttaatga gcaacaatat gcgcaagatt ttatcgctta cgaaaagaca atttctgata
      421 agcaatttga aattgaaaaa gtagatatag ctgattggtt attgcaaccg agagaatttt
      481 agaggttggt tgaaaatggc taaaattggt tatgcacgtg tcagtagcaa agaacagaac
      541 ttagatagac aactgaaagc gttagagggc gtttctaagg tcttttcaga caaattaagc
      601 ggtcaatcgg tcgaacgccc acaattacaa gctatgctta actatattcg tgaaggggat
      661 atagttgttg ttactgaatt agatcgatta ggacgaaata ataaagaatt aacagaattg
      721 atgaatcaaa ttcaaattaa gggggcaacc ctggaagtct taaatttacc ctcaatgaat
      781 ggtattgaag atgaaaattt aagacggctg attaataatt tagtgattga attgtataag
      841 taccaagcgg aatctgaacg caaacgaatt aaagaacgcc aagcccaagg aattgaaatt
      901 gctaagaaaa aaggaaaatt caaagggcga caacctaaat tcaaagaaaa tgatccacgt
      961 ttacaacacg ctttcgattt atttttgaat ggttgttccg ataaagaagt tgaagaacaa
     1021 actggaatta atcgccgaac gtttagaagg tatcgatcaa gatacaacgt gacagtagat
     1081 caaagaaaaa aacaatgaaa agagggatag ttaatgagta cggttatttt agctgaaaaa
     1141 ccaagccagg cattagccta cgcaagtgct ttaaaacaaa gcaccaaaaa agacggttat
     1201 tttgagatca aagacccact atttacagat gaaacgttta tcacctttgg ttttgggcat
     1261 ttagtcgaat tagcagaacc aggtcattat aacgaaaagt ggcagaactg gaaacttgaa
     1321 tctttgccga tttttcctga tcgatacgat tttgaagttg caaaagataa gggaaagcag
     1381 tttaaaattg ttgctgaact tctcaaaaag gcaaatacaa ttattgtcgc aacagatagc
     1441 gacagagaag gtgaaaatat cgcctggtcg attatccata aagcaaatgc cttttctaaa
     1501 gataaaacgt ataaaagatt atggatcaat agcttagaaa aagatgtgat ccgaagcggt
     1561 tttcaaaatt tgcaaccagg aatgaattac tatccctttt atcaagaagc gcaaacacgc
     1621 caaattgccg attggttgat cggcatgaac gcaagccctt tatatacctt gaatttacaa
     1681 caaaaaggcg tacaaggtac attttcatta ggacgtgtac aaacaccgac tttatatctc
     1741 atttatcaac gccaggaagc aatagaaaac tttaaaaaag aacctttttt cctgaataat
     1801 tcatagtttt actaatagtc tttcctaaca ttgatttaat agtctttaaa gtattctgct
     1861 tcatcaccca ttaggtgatg aaaaaagaac ccctttctga tttagcggac aaatactttg
     1921 acctaatctc agaagatata aaagaaaaaa taataaaata tccgatttat actttgtata
     1981 aagaactaaa gtagttagca aatcatttac agcaaatcac tatgttccac ataccatttt
     2041 acatacttac cttatccacg acacatgttg agatagtatc gaagataaag aaagttgctc
     2101 catgttgttt ttgcgagatg gggaaatcaa agccacattg acaaccatga tgaataagct
     2161 tgctttcagt cataagctaa tcctagaacc acttttcaag tcagttagcc aaatcgatga
     2221 agaaagcgac cgtgaaagaa tggacgctat tgataagcta atggagcaac tattggaaga
     2281 acgcaatacc cttattgcac tgatgtccaa aggtttccta gaacctgctc tttttaatca
     2341 ggaacgaaat gttttagata gtgagattaa aaatcttact accgaaaaaa caaacctggt
     2401 aacgaactct gcgagtgggg ttttgcgagc aaacgagata aaggacctca ttaattatgt
     2461 gtcagcagat aattttaatg gtgactacac ggaagaacta tttgaagaat ttgtagtgaa
     2521 catcattgta aattccaggg atgagctgac attcaatttg aaatgcggtc tttccctgaa
     2581 agaaaaggtg gtgagataaa tggcatatat tccatatgga tacaaaattc aagatggagt
     2641 ggttactgtc gatgaaaagg cagcaggtca agtaaaggta ttctttgaga aatacatatc
     2701 aggactatcc cttacagtgg ctggcgaaca ggcaggtatt gaaaagacac attctgtgat
     2761 ggggcgcatt ttgaaaaacg tcaactacct tggaaatgat acgtatccag caattattga
     2821 taaagagata tttgataaag ctgaagaagt tagagataaa cgtgcaaagg atttaggacg
     2881 agtggtagag cttgccgctt tcacctctcc ccctcccaaa gaacgattca aaatgaaaaa
     2941 ggcagataat aagatgccag tggatccttt tgaacgagca gaatacttat acagtctgat
     3001 agaaagcgag gaataaagtg acagagaaaa atataatggt tattcctgct cgtaaaagag
     3061 taggaagtac agccgcaaaa gaaaagataa agaaacttcg tgttgctgcc tattgccgtg
     3121 tttctacaga aacagaagaa caaaattcta gctatgaggt tcaggtctca cactatacag
     3181 agtttataaa gaaaaataat gaatgggagt ttgctggcat ctttgcagat gatggtatct
     3241 ctggtacgaa cactaaaaag cgtgacgaat ttaatcgcat gattgcagag tgtatggacg
     3301 gtaacatcga catggttatt acaaaatcca tcagccgatt tgcgcgtaac accctagact
     3361 gccttcaata cattagacag ctcaaggata agaacatatc agtttatttt gagaaagaga
     3421 acatcaacac cacggatgcc aaaggtgagg ttttgctgac tattatggca tctttggcac
     3481 agcaggaaag ccagagcctt tcacaaaacg ttaagcttgg gctacagtac cgataccaac
     3541 aaggaaaggt gcaggtcaac cataagcgat ttatgggcta cacgaaagat gaagatggaa
     3601 atttaactat tgtccccgaa gaagctgaga ttatcaaacg catctaccga gaataccttg
     3661 agggtcagag tctagtgggc attggtcgag cccttgaaaa ggatggtatt ttaacagcag
     3721 cgggaaaacc aagatggcga ccagaatcag ttaagaagat acttcaaaac gaaaaataca
     3781 tcggagatgc ccttctgcaa aagactgtca cagtagattt tctgaccaag aaacgagtga
     3841 aaaatgaagg gcatgttccc caatattatg ttgaaaatag ccatgaagcg attattccta
     3901 aagagttatt tttgcaggcg caagaagaaa ttcatcggag aagcaatatc tacacaggag
     3961 aaggcaagaa caaaagaatt tacagtagca agtacgcttt aagtgccatc accttctgtg
     4021 gagattgtgg cgatatttat agacgggtct attggaatat ccacggaaga aaagaatttg
     4081 tctggcgatg cgtgactaga atcgagcaag gtcctgaagt ttgtaagaac cgaaccgtaa
     4141 aagaagatga actttatggt gcagtaatga ctgcgattaa taagctactt gcaggtggga
     4201 acaatatgat aaagacactg gaagagaata ttcatgctgt gattggcgaa accacagaat
     4261 accaaatttc agagattaac aactcactag aggaaaaaca aaaagaacta atcaagctgg
     4321 cgaacaaggg tcaagactat gaccacttag cagatgagat tgatgagctg agagacaagc
     4381 gacagatcct tttagtagaa gatgcctccc tcagtggcga gaacgagcga atcaatgagc
     4441 tgattgaatt tatccgcaag aacaaattcc gcaccttaga atatgatgat aagcttgtaa
     4501 ggaagataat ccagagcgtt acagtctatg aaggccactt cgtcatagcc ttcaaatctg
     4561 gcatcgaaat ggaaatatga aaaccagaag taaatagccc atgactctac agtagagttg
     4621 tgggttttct tttgcttgct gattataata atattttaat aactattgtg tttatcaacc
     4681 aaatggttta taatattctt agcgtaaact tggaggtgct gtatgactac ggcagaaatg
     4741 attaaagaac tgtgtgagca aatgaatata agtgtttccg aacttgctag acgtattggc
     4801 cagactccac agaatttcaa taaaaaatta caacgagaaa cagtaacctt ggatgagttg
     4861 aaggccattg ctgatgtgct aggtgtcaag tttgtgcagg catttatttt accagatgga
     4921 gaagaaataa aaatatctaa cgaataaagg aggatgttta tatggtaggt aatgttattc
     4981 aaatagtaac agagaaatta tcatctttgc cttttataga aggcatcgta ttagggggct
     5041 cacgtgcaag aggcacccat acagaaaatt ctgatataga tatcggaatc tattacaatt
     5101 cagactcatt tgacctgaca gcgattaatc aaattgctac agagttggat gatgagaata
     5161 gaaacaacct tgttgtacct cccggagcgt ggggtgattg ggttaatggc ggtggatggt
     5221 tagttataaa cgggtgtcat gttgacttga tattacgtga tataaaacgg gtggaacaaa
     5281 taatcaaaga tacggagcaa ggaattgtta ctgccaatta tcagaccggg catccccatg
     5341 gttatataag tgctatgtat cgtggagaat tagcgattag taaaatacta tatgctaaga
     5401 acgaaagctt atgcgaatta aaaaagcagg cagaaattta ccctactgct ctaaagaaaa
     5461 gcttgatgaa cttttttata tttgaagctg aattctcttt aatgtttgta aaagcaaatg
     5521 cgggggcaga ggataaatat tatattgcag gccatgtttt tcgtattatt tcatgcttaa
     5581 atcaagtact atttgcatgt aataatgctt attgcattaa cgaaaagaaa gctataaaac
     5641 tgcttgaaac ttttgaatat aaacctgaaa aatatgccga aagagttaat catatttttg
     5701 aagtactcgg tctttctctt tttgaatgct acgacatgac cgagaaactt tataaagaag
     5761 tgaatgaaat tgtatcggag ataaataact ttttaaacga ggagagttca gatgaaagaa
     5821 aacaaatatg atgataatat attttttcaa aaatacagtc aaatgagtcg ctcgcagaaa
     5881 ggactggctg gtgcgggaga atgggagact ttgaaaaaga tgctacctga ttttaagggt
     5941 aagcgtgtgc ttgatttagg atgcggctat ggatggcact gtatatatgc gatggaaaac
     6001 ggtgcttcct ctgtagtagg tgttgatatt tctcataaaa tgctcgaagt agcaaaagga
     6061 aaaacccatt ttccacagat tgaatatgaa tgctgtgcca tagaagatgt ggatttccca
     6121 gaggagagct ttgatgtaat actaagttcg cttgcgtttc attatgtagc agactatgag
     6181 aatttaataa aaaagatata taggatgctg aaggctggtg gcaatttagt ttttacagtt
     6241 gaacatcctg tttttactgc tcatggaaca caagactggt attataacga aaaaggagaa
     6301 atactgcatt tcccggtgga caattattat tatgagggca aacggacagc tatgtttttg
     6361 gaagaaaagg ttacaaaata tcatagaaca ctgaccacat atctaaatac actgctttca
     6421 aatagtttta taataaatca gattgtggag ccacagccgc cagagaacat gatggatatt
     6481 ccggggatgg cggatgaaat gcgacgccca atgatgctga ttgtatcggc aaaaaagaag
     6541 atgtaataat atagaaaaaa taaacgagga gtatgtaaat gagatcagaa aaagaaatga
     6601 tggatttagt actttcttta gcagaacagg atgaacgtat tcgaattgtg acccttgagg
     6661 ggtcacgcgc aaatattaat atacctaaag atgaatttca ggattatgat attacatatt
     6721 ttgtaagtga tatagaaccg tttatatcta atgatgactg gcttaatcaa tttgggaata
     6781 taataatgat gcaaaagccg gaggatatgg aattattccc acctgaagaa aagggatttt
     6841 cctatcttat gctatttgat gattacaata aaattgatct taccttattg cccttggaag
     6901 agttagataa ttacctaaag ggcgataaat taataaaggt tctaattgat aaagattgta
     6961 gaattaaaag ggacatagtt ccgactgata tagattatca tgtaagaaag ccaagcgcaa
     7021 gggagtatga tgattgctgc aatgaatttt ggaatgtaac accttatgtt attaaaggat
     7081 tgtgccgtaa ggaaatttta tttgctattg atcattttaa tcagattgtt cgccatgagc
     7141 tgctgagaat gatatcatgg aaggtcggca tcgaaacagg ctttaaatta agtgtaggca
     7201 agaactataa gtttattgaa aggtatatat ccgaggattt gtgggagaaa cttttgtcca
     7261 cctaccggat ggattcctat gaaaacatat gggaagcatt atttctatgc catcaattgt
     7321 tcagggcggt atccggtgag gtggcggaaa ggcttcatta tgcctatccg gagtatgata
     7381 ggaatataac aaaatatacc agggacatgt ataaaaaata cactggtaaa accggctgcc
     7441 tggatagcac atatgccgct gatatagaag agaggcggga acagtgatta cagaaatgaa
     7501 agcagggcac ctgaaagata tcgataaacc cagcgaacca tttgaggtga taggtaagat
     7561 tataccgagg tatgaaaacg agaattggac ctttacagaa ttactctatg aagcgccata
     7621 tttaaaaagc taccaagacg aagaggatga agaggatgag gaggcagatt gccttgaata
     7681 tattgacaat actgataaga taatatatct ttactaccaa gacgataaat gcgtcggaaa
     7741 agttaaactg cgaaaaaatt ggaaccggta cgcttatata gaagatatcg ccgtatgtaa
     7801 ggatttcagg gggcaaggca taggcagcgc gcttatcaat atatctatag aatgggcaaa
     7861 gcataaaaac ttgcatggac taatgcttga aacccaggac aataacctta tagcttgtaa
     7921 attctatcat aattgtggtt tcaaaatcgg ctccgtcgat actatgttat acgccaactt
     7981 tgaaaacaac tttgaaaaag ctgttttctg gtatttaagg ttttagaatg caaggaacag
     8041 tgaattggag ttcgtcttgt tataattagc ttcttggggt atctttaaat actgtagaaa
     8101 agaggaagga aataataaat ggctaaaatg agaatatcac cggaattgaa aaaactgatc
     8161 gaaaaatacc gctgcgtaaa agatacggaa ggaatgtctc ctgctaaggt atataagctg
     8221 gtgggagaaa atgaaaacct atatttaaaa atgacggaca gccggtataa agggaccacc
     8281 tatgatgtgg aacgggaaaa ggacatgatg ctatggctgg aaggaaagct gcctgttcca
     8341 aaggtcctgc actttgaacg gcatgatggc tggagcaatc tgctcatgag tgaggccgat
     8401 ggcgtccttt gctcggaaga gtatgaagat gaacaaagcc ctgaaaagat tatcgagctg
     8461 tatgcggagt gcatcaggct ctttcactcc atcgacatat cggattgtcc ctatacgaat
     8521 agcttagaca gccgcttagc cgaattggat tacttactga ataacgatct ggccgatgtg
     8581 gattgcgaaa actgggaaga agacactcca tttaaagatc cgcgcgagct gtatgatttt
     8641 ttaaagacgg aaaagcccga agaggaactt gtcttttccc acggcgacct gggagacagc
     8701 aacatctttg tgaaagatgg caaagtaagt ggctttattg atcttgggag aagcggcagg
     8761 gcggacaagt ggtatgacat tgccttctgc gtccggtcga tcagggagga tatcggggaa
     8821 gaacagtatg tcgagctatt ttttgactta ctggggatca agcctgattg ggagaaaata
     8881 aaatattata ttttactgga tgaattgttt tagtacctag atttagatgt ctaaaaagct
     8941 ttaactacaa gctttttaga catctaatct tttctgaagt acatccgcaa ctgtccatac
     9001 tctgatgttt tatatctttt ctaaaagttc gctagataga gttctatatt agagatgtaa
     9061 agagttttgg tgaagaggtt tgtgagtatg gcttttataa ccagggtgca atgagaagca
     9121 ctaacagcag ctagcttaag aacgcatagg atatactttt tatggaagtc acagaggagg
     9181 aataaaattt gaacaggatt aacagagtaa cctctattct tattcagctg caatcaaaaa
     9241 aaataattcc tgccaaagaa attgcacagc gatttaatat aagcttaagg acagtttaca
     9301 gagatatccg gacacttgaa gaagccggaa taccaattgg atctgaggcc ggaaaaggat
     9361 attttcttgt agagggcttc ctacttccgc cggtaatgtt tacagcggcg gaagtgggtg
     9421 cattgattac agcagggaaa tttttaaatt gccatggaga tgaatcattt ataaaggatt
     9481 ttgattcagc tatgtataaa atcaaatcta ttttgaagca tggtgaaaaa aactatgcac
     9541 aggagttgga gaacagtatt aacgtgtaca gcacatctgg acagaaaaat acattggcgg
     9601 ataacgttat tgcagcaatt cagactgcaa tctgcaataa aagggtaata tcaattcaat
     9661 atcctgcatc aggagggcaa gaaccggaaa gcagaatgat agagcctata tcactggggt
     9721 tttatgaaca gaactggtac ttaatcggtt ttgcaggcta agaaatgaat ataggaattt
     9781 tcgtgtggat cggattaaaa gcatttgcat agaagaagag ctctgtcaaa gccatgatgg
     9841 ctctttggaa caaatattaa aacaaatgct ttcatataaa aaactatatg ccctacaatg
     9901 ccgttgtaaa aattggggaa aagggatata ttgattttat atctttctca aaataaatat
     9961 aaaagccctt taaagagggc ttttatatat taatcacaaa tcacttatca caaatcacaa
    10021 gtgattaatc acaaatcact tgtgatttgt gattcttaat gatacaatat tactatacaa
    10081 aaaaagaatg gggcgtagtt atggagaagg aaaaactaaa aatacttgaa gaattaagac
    10141 gtattttaaa caataaaaat gaagcaatta ttatcttgaa taattacttt aaaggtggtg
    10201 ttggaaagtc caaattatcg actatgtttg cttacttgac agacaaattg aatttaaaag
    10261 ttttaatgat cgataaggac ttacaggcaa cattgacaaa agacttagca aaaacttttg
    10321 aggtagaatt gccacgtgtc aatttttatg aaggcttgaa aaatggaaac ttggcttctt
    10381 ctattattca tttgactgat aatttagact tgatccctgg cacgtttgat ttgatgttac
    10441 tgccaaaatt aactcgctca tggacgtttg aaaatgaaag tagattgctt gctactcttt
    10501 tagcaccttt aaaaagtgac tatgatctta ttattattga tactgtacca acgccaagcg
    10561 tttatacaaa taatgcaatc gtggcgagtg attacgttat gatcccttta caagcagaag
    10621 aagaaagtac aaacaacatt caaaactata tttcctattt gattgatttg caagaacagt
    10681 ttaaccctgg actagatatg attggttttg ttccttattt agttgatacg gacagcgcaa
    10741 cgataaaatc aaacctggaa gaactgtaca aagaacataa agaggataat ttggttttcc
    10801 gaaatattat caagcgaagt aataaagtaa gtacttggtc taaaaatggc attacagaac
    10861 acaaaggcta tgacaaaaaa gttttgtcta tgtatgagaa cgtatttttt gaaatgattg
    10921 agcgaatcat tcaattagaa aatgaaaaag aatagaatca caaatcacaa gtgattaatc
    10981 acaaatcact tgtgatttgt gataggtgat gataaaataa atagtaagaa gaaatagaaa
    11041 gaagtgagcg atcgtgggaa atttaggcgc acagaaagca aaacgaaatg atacgccaat
    11101 cagcgcaaaa aaagatataa tgggggataa gacggttcgt gttcgtgccg acttgcacca
    11161 tatcataaaa atcgaaacag caaagaatgg cggaaacgta aaagaagtta tggatcaagc
    11221 cttagaagaa tatatacgga aatatttacc tgacaaactt taaaaggagt gaaaatgaaa
    11281 tggcagttac gtatgaaaaa acatttgaaa ttgaaatcat taatgagtta tcggcaagtg
    11341 tttataatcg ggtattaaat tatgttttga atcatgaact agatactaaa aatactcgtt
    11401 tactagaagt gaatctttta aatcaattag aagtggcaca agaagttgat ttatttcaac
    11461 aaccatttga agaattacaa gctattcatg agtattggcg gtcaatgaat caatattcaa
    11521 aacaaatttt gaataaagag aaagtggctt aacatggcga atattactga cttcaccgaa
    11581 aagcaatttg aagatcgttt agaaaagaat gttgaacgac taactaaaaa tagactagcg
    11641 gttgaatcgc caaccgcttt tttacttggt gggcaaccag ggtcagggaa aaccagtttg
    11701 cgatcagcaa tttttgaaga aacacaaggg aatgttattg tcattgataa tgataccttt
    11761 aaacaacagc acccaaattt tgacgaatta gtgaaactct atgaaaaaga cgtagtaaaa
    11821 cacgttaccc cttattcgaa tcgcatgaca gaagcactta ttagccgttt aagcgatcaa
    11881 ggctataatt tagtgattga aggaacagga cgaacaacag acgttcccat tcaaacagcc
    11941 acaatgcttc aatctaaagg ttatgaaaca aaaatatacg tcatggcagt accgaaaatt
    12001 gaatcatact taggaacgat tgaacgatat gaaaccatgt atgcagatga tccaatgaca
    12061 gctagggcaa caccaaaaca agcgcatgat attgttgtca aaaacttacc gaccaattta
    12121 gaaacccttc ataaaacggg cttatttagc gatataaggc tttacaatag agaaggagtg
    12181 aaactctatt caagcttaga aacgccttcc attagtccga aagagacctt agaaagagaa
    12241 ttaaatcgta aagtatcagg gaaagaaatt caaccgactt tggagagaat agagcaaaaa
    12301 atggttcaaa atcaacacca agaaacccct gaatttaaag caattcaaca aaaaatggaa
    12361 agcttgcagc tacctacacc accaataccc aaaacaccta aacttccagg tatttaaacc
    12421 ttaaaaaagg aaaagagtag ttaccaaaaa acggtaacta ctcttttttt ataaaaacat
    12481 ttcctcatgt tggggtcccg agcgcctacg aggaatttgt atcgataaga aatagattta
    12541 aaaatttcgc tgtttttttc taatttcatt ttgaggtgaa ttaattggta gttattagag
    12601 gtgccctata cctaataatt tatctacatt ccctttagta acgtgtaact ttccaaattt
    12661 acaaaagcga ctcatagaat tatttcctcc cgttaaataa tagataacta ttaaaaatag
    12721 acaatacttg ctcataagta acggtactta aattgtttac tttggcgtgt ttcattgctt
    12781 gatgaaactg atttttagta aacagttgac gatattctcg attgacccat tttgaaacaa
    12841 agtacgtata tagcttccaa tatttatctg gaacatctgt ggtatggcgg gtaagtttta
    12901 ttaagacact gtttactttt ggtttaggat gaaagcattc cgctggcagc ttaagcaatt
    12961 gctgaatcga gacttgagtg tgcaagagca accctagtgt tcggtgaata tccaaggtac
    13021 gcttgtagaa tccttcttca acaatcagat agatgtcaga cgcatggctt tcaaaaacca
    13081 cttttttaat aatttgtgtg cttaaatggt aaggaatatt cccaacaatt ttatacctct
    13141 gtttgttagg gaattgaaac tgtagaatat cttggtgaat taaagtgaca cgagtgttca
    13201 gttttaattt ttctgacgat aagttgaata gatgactgtc taattcaata gacgttacct
    13261 gtttacttat tttagccagt ttcgtcgtta aatgcccttt acctgttcca atttcgtaaa
    13321 cggtatcggt ttcttttaaa ttcaattgtt ttattatttg gttgagtact ttttcactcg
    13381 ttaaaaagtt ttgagaatat tttatatttt tgttcatgta atcactcctg aagtgattac
    13441 atctataaat aaatacagaa gttaaacgat ttgtttgtaa ttttagttat ctgtttaaaa
    13501 agtcataaga ttagtcactg gtaggaatta atctaacgta tttatttatc tgcgtaatca
    13561 ctgtttttag tctgtttcaa aacggtagat g
//
LOCUS       DBBGSZ010000056        13532 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.058, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000056 DBBGSZ010000000
VERSION     DBBGSZ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13532
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.058"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            120..1754
                     /locus_tag="ACIZE5_002452"
     CDS             120..1754
                     /locus_tag="ACIZE5_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HGC6109561.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTFKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
     gene            complement(2021..3190)
                     /locus_tag="ACIZE5_002453"
     CDS             complement(2021..3190)
                     /locus_tag="ACIZE5_002453"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGC6109562.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            3394..4569
                     /gene="mltG"
                     /locus_tag="ACIZE5_002454"
     CDS             3394..4569
                     /gene="mltG"
                     /locus_tag="ACIZE5_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HGC6109563.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            4705..5184
                     /gene="greA"
                     /locus_tag="ACIZE5_002455"
     CDS             4705..5184
                     /gene="greA"
                     /locus_tag="ACIZE5_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HGC6109564.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            5353..6084
                     /gene="liaF"
                     /locus_tag="ACIZE5_002456"
     CDS             5353..6084
                     /gene="liaF"
                     /locus_tag="ACIZE5_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HGC6109565.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            6081..7148
                     /gene="liaS"
                     /locus_tag="ACIZE5_002457"
     CDS             6081..7148
                     /gene="liaS"
                     /locus_tag="ACIZE5_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     LiaS"
                     /protein_id="HGC6109566.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            7155..7787
                     /locus_tag="ACIZE5_002458"
     CDS             7155..7787
                     /locus_tag="ACIZE5_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGC6109567.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            7927..8592
                     /locus_tag="ACIZE5_002459"
     CDS             7927..8592
                     /locus_tag="ACIZE5_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HGC6109568.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            8620..8913
                     /locus_tag="ACIZE5_002460"
     CDS             8620..8913
                     /locus_tag="ACIZE5_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HesB/YadR/YfhF family protein"
                     /protein_id="HGC6109569.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(8981..9928)
                     /locus_tag="ACIZE5_002461"
     CDS             complement(8981..9928)
                     /locus_tag="ACIZE5_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HGC6109570.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(10106..10909)
                     /locus_tag="ACIZE5_002462"
     CDS             complement(10106..10909)
                     /locus_tag="ACIZE5_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HGC6109571.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            11055..11969
                     /locus_tag="ACIZE5_002463"
     CDS             11055..11969
                     /locus_tag="ACIZE5_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HGC6109572.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            12017..12487
                     /locus_tag="ACIZE5_002464"
     CDS             12017..12487
                     /locus_tag="ACIZE5_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HGC6109573.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            12572..13180
                     /locus_tag="ACIZE5_002465"
     CDS             12572..13180
                     /locus_tag="ACIZE5_002465"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HGC6109574.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            13314..13514
                     /locus_tag="ACIZE5_002466"
     CDS             13314..13514
                     /locus_tag="ACIZE5_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HGC6109575.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
BASE COUNT         4580 a         2040 c         2603 g         4309 t
ORIGIN      
        1 aaacactact tttgtaatat aaaaaatatt ttattaataa taaaattaat cacattttat
       61 atagtgacta atctagtgtt taaaaaaaat aaatgatact atatgtaata taaaaaaaca
      121 tgaggtggta tatgaatttg aaaaaaattt tttctgtaaa aatatttata gtttatgcat
      181 ttgttagttt attatattta tttccagcat ttaaaaacat ggaaatattt ggcttttatg
      241 atacggcatt tcacattaat cgtgcgttaa gtttagaatc tatttttagc tcccctatta
      301 attttgaaac gtttagatca tatggcatgc aagtaaataa tttttaccca tggttaactc
      361 tatatccttt atttttattg atcaagttta ctaatttagc aataggctat aacctttttc
      421 tttatattgt tacgctcatt actctattta tatgtcatta tgtaatgtat gaaattacca
      481 aaaaacatgt tactagctcc tttttcgcta ttatatatac aacatcttct tttaggagtg
      541 tagaaatatt tcttcgaggg gcaatggggg aattactcgc aatgtcaata cttcctctta
      601 ttttactcgg gtttataaag ctttacgact caaaaaaaga atcttgggtt atgttggcga
      661 ttagcatgac tttattaatt tacactcatg ttctttctgt agctatgact atggtaatga
      721 ttataattgc tttaattatt caattttatc ggaaaaagaa aatagaaatc ttcttaatta
      781 ttaaattaat aaaagctgct atagttactt tacttctttc actagcgttt ataggtccta
      841 tgattgagca gacattgtat caagatctga atagacctta tgtggatata ttacaaaaaa
      901 gagcaattta tctgggtaaa gagtttttga ttggaagtat agattcagaa ttactatcat
      961 ttggtattgg cttaactttg cttatttgtt taattatact aacatttaac tttaaaaaat
     1021 taggaatctt atctaaaatc acttatataa tgggtataat atctattcta ctttgtacaa
     1081 aaatatttcc atggtttgcc ttacaaaata ctcctttaaa tattattcaa gctccttggc
     1141 gttttatgat attttcaaca ttgttcatat ctttttcagt atctctattt atttctccac
     1201 agttggaaaa attttcttat acaaggagaa gaaattttat actattatta atattagcta
     1261 tttcaatttt aaattattca tcagtagtta acatggtgaa agaaatgaat tttcaaggaa
     1321 cttattctaa tgaacaaatg gaaaataaac ttgaagaatt tgagaatttt gattatgtac
     1381 ctataggcta taaaaaagat caattgcttt tgaaaaacca tcaagttaca gaagatggtc
     1441 aagttattta tagtagcttt tctccaaata aagatgaaat tacatttacg tttaaatctt
     1501 caaaaggcaa aacaatagtt ttacctgtat tccggtataa aggattaacg gttactgtta
     1561 attcaaaaaa tgctacagta ctaaaacaag gaggtccttt tgttacagta aaaagtgaaa
     1621 gtggaataaa taaagtaaca atcaggtatt catacacatt tttttctaaa atctcattat
     1681 ttatttctat aatcacgcta attgttcttc ttttttattg cataaaatta aaaataagaa
     1741 caagccatga atgatttgct agcacatatt ttagcaatct aaagatacta ttttagattt
     1801 aataggccct ttgtcaaata atgttggtaa agagaaatct tagaataatt tggacagaac
     1861 agaaagaaga acacctcttt ctgttctgtt tatttggaat taaagtctgt agcaaaaatt
     1921 gatttttaga tttgtcccac actctttcct acgtttagtc gagtactttt tttaagcaaa
     1981 tgctattcaa agaagtagta tttgctatct tttcatcata tcagctattt gccaacttag
     2041 tagttccttc catcaggtca tagatttggt ttcttagatc agcagtaggc agtttgatag
     2101 ttttgtcagc ttttatattg ctttccatga tgatagcatc ctgtgaatct ttgctaaata
     2161 tagcagatgt atcaaaagag tcgatatttc cttgcgacag gatataatta tctccgctat
     2221 ataccccacc actatatgga tgtccattcg cattttcacg ccataatgag aagagtaagt
     2281 ctttggaaac tagttttcca gataaaactt gtgtaaacag cgtatttaaa tcatagacgg
     2341 acatactgat attaccagtc cctaattcgt tatggatctc tgtttcagat tctgtcagtg
     2401 gtttaaagta atcatcctct ttagacattt gataggatag tgcatgattg gatgaatttt
     2461 tgacttggtc ataaaatttt gtatgctgta atcctaaagg ttcgatgata tcatcggtca
     2521 ataatttttc atacggttga tttgttaatt tgatcaaaat tccagtcaat atggtaaagt
     2581 tcaatgaatc ataatgagag gtctgataat ctgtaaattt taagtgctga atcgcaaatt
     2641 gaacgacttc ttcatcagtc atcggtatgg ttggagaagc agttcggtgc aagcctgagc
     2701 gcatatacag caagtcacgg atagtaattt gctggctgcc agcaatttgt ggatagaatt
     2761 gagccagctt agtatctaaa gaaaggtgcc cacgctcgac ttgttttaaa atcaaaagag
     2821 tagtcaatgc tttttgaacc gaaccaatct gataataaag agaaggatca tttggttgtt
     2881 gcgtgagttt attcgcatag ccatagcctt tttccatgat gatgcgatta tttttcttta
     2941 cgtaaattga gccaatataa tcattttttc ttaatagttg atcgattttt tcaacgagct
     3001 gttgttcatt ggtagtcagt atcaactttt tttgagctga ttgagcatgg gcaactatct
     3061 gagagtgttc attattgtaa aattgccatc caagaatagt tcctgtagag aacgcactaa
     3121 ggctaaacaa cacgacaacg atcattaaaa atgaatattt tcttttttta gcatgttttc
     3181 cttttttcat aatagtttat ttagtctcct ttctttttta cagaaagaat aaagctaaaa
     3241 tagcttgtat cttgataaca tttattttaa tcttatagta atggatttac tacttacatt
     3301 tttgatagaa tatttaaata aaatcattca cgccaattca aatatcatgt ataatgaata
     3361 aagttacgaa cttgatagta aggaggagtt gttttgtcag gaaacaaaca acacccaagt
     3421 aaagataaaa aagaagccag taaggcagct acagcagata taatcgacaa gcggagaaat
     3481 ctgcgtaaaa aagaagataa gattgtgagg aagatcattt tagtgattgc tcttacatta
     3541 ttgattattg gcggatttct tggatttacc gtgtatcgtt atgtagatag cgggttgaag
     3601 cctttagata aatcagatga ccaattagtc caagtcgaga tcccgagtgg ctcttctaac
     3661 aagcagattg gtgagatttt ggagaaggac aatattatta aaagcgggat tgttttcaat
     3721 tattatacaa aatttaaaaa tttaactggc tttcaagctg gctattatca gttagcgcct
     3781 aatatgactc ttgacgagat tggcaaacag ttgcaagaag gcggtacttc tgagccaaca
     3841 aaagttgcag atgggaaaat tgccattcca gaagggtacg atatcgatca gattgctgaa
     3901 cgggtagcga aggtaactgg taaagacaag aaagaatttt tagatttagt gaatgatgag
     3961 actttcttta acgagttgca ccaaaaattc ccagaactgt tggaaagtgc atctaaagct
     4021 gagaacacaa aataccgttt ggaaggttac ttattcccag ccacatatga ttattacacg
     4081 agtacttcgc ttaaggatct agtgattgaa atggtgaaca agacgaatac ggtcatgcaa
     4141 aactattatt cagctatcaa gcagaaaaat ttgactgtac aagaagtttt aactctagct
     4201 tctctagttg aaaaagaagg cgtaaaagaa aatgatcgta aaaacattgc acaagtcttc
     4261 tttaaccgaa tcaaagcaaa tatgccactt cagtcagata tctctgtttt atacgcatta
     4321 ggtgaacaca aagaattagt gacgtatgaa gatacagctg tagattcacc atataatttg
     4381 tataccaata ccggctatgg acctggacct tttgacaatc caagcgaaga ggcaatcaag
     4441 gcagtattag aaccagcaga aaatgactat tattatttcg tagcagatac gagcactgga
     4501 aatgtttatt tcgctaaaac ttatgaagaa catatggaat tagtggaaaa atatgtaaat
     4561 aattcttaga aaaacaggct ctagacattg atcattttta gaaaaacatt tacatttgaa
     4621 gaaaagcgtg gtaatctttt ttggactata ttcctcaaaa gattaccttt tgcggtattt
     4681 tatcgaaaaa aggagacgtt acacatggta gagaaagttt atccaatgac tctagaaggt
     4741 aaagaaaaat tagaaaaaga attagaagaa ctaaaaacag tcaaacgcgg agaaatcatt
     4801 gaacgaatca aaattgcccg cggtttcgga gatctttccg aaaactctga atatgaatca
     4861 gcgaaagatg aacaagcatt tgttgaagga agaatcacaa caattgaaaa tatgattcgt
     4921 tttgctcaaa tcatcgataa cgacggtgta gatgcagatg aggtatcaat tggtaaaaca
     4981 gttacattca tcgaactacc agatggagaa gaagaagagt acacgattgt cggaagcgct
     5041 gaagcagatc cgttttctgg caaaatttcc aatgattctc ctattgcgca agcattgatt
     5101 ggcaaacgta aaaatgatga agtaactatt gctactccag gtggcgatat gttagttaaa
     5161 atcgtcaaag tagaacaagc gtagtctgac tgaaagatct agagagttca tcttactgat
     5221 gatacactct agatcttttt ctctttgtgt attttagatt tcaacaaacg atcttacatc
     5281 taaagtccta tagccaacag ttaaaaaaat aggtatgatg aaatgagaat gtgtcaggag
     5341 ggagaaagag cgatgaatag ttcttggcgt ttttttgtgg tagttgaagc actactgctg
     5401 ttatttgctg tttggcaaat cgtaaacaat actggacttt tgcttttagt gatattcggt
     5461 attttcaata tatatctagc tatgcgcaaa catcctcgta ctaaatttca aaattttcaa
     5521 ttgatattag gaagtttggt catttttttt agcttagtca acagtcctgc tttatggatg
     5581 atggctgtat ttgccgtttt atttattggt ctgaaaggtg tagagatttc agggatagat
     5641 ttaaccaaaa atgctttttg gcgaaagaaa cagatcatga tgatccaaac agagcaatta
     5701 aaaacacata ataatgagcg gaaaagacag caattattcg gtaaccaacg tattggaaac
     5761 gacgtctatg aatgggacga tatcaacatc gccgtcattt ctggtgatac tatcatagat
     5821 ttgggcaata cgcttttgcc aaaagatgat aatattgtga ttgtaagaaa agggataggc
     5881 agaacacgga tcttagtacc tttgggcgta gccatccgat tagagcatgc gacattagta
     5941 ggaaatgtct tgtttgaaga agagcaattt tctttgaaaa atgaacaaat caaaatctac
     6001 agcagtgatt atgatgaaaa ccctcgtaga ttgaagatta ttactaatac cttgattgga
     6061 gatgtcgagg tgatacgaat atgatgggaa aaatatccag agcgatgcta gctgtttatt
     6121 cggggattgc ggctttcctt attattctat tttcactttt cacttatttt tatgccagca
     6181 atcaaagtca ttggtgggga gaattactgc gtgcacgttt attatatgtt ccgcttatct
     6241 tccatttgtt agccatttcc ttaggtgtag gattaattgt ctttctatta ttatcactta
     6301 ttcaaaagac aaaatacggg aaaatcgaag aaaagctgcg tgcactttct tctggcaatt
     6361 atgaatccaa attgttgctt cttccgatcc caagtgcatc ggacgattta tacatcaaag
     6421 atattgataa ggaaatcact aagataaaag aaaaaatgat tgaagtatct agtgaattac
     6481 aaattgtaac gagccgtccc caatatgtag atggacaaac caaagaagaa attttagaat
     6541 tagaaagaca tcgattagcc cgtgagctgc atgattcagt ttcgcaacaa ttgtttgcag
     6601 caatgatgat gatgtcggca ttgacggagc aagcagaaaa aagcgagaca ccagaaatgt
     6661 ttcgcaagca gttgaaaatg gtagcagaga tcatcaacgc ttcccagtct gagatgcgtg
     6721 cgctgcttct tcatctacgt ccagtcaatt tagaagagaa aagtttaaag caaggtatcg
     6781 agcagttatt gaaggaattg caaaataaaa tccagatttc gctgaaatgg gatgtagaag
     6841 atgtaaaact atctagttcc attgaggatc acttgttccg aatcgttcaa gaattgttat
     6901 caaatacatt aagacatgct aaagccaatg aattagaggt atatttgcac aaaatagaca
     6961 ataatctttt gttacgtatt attgacgacg gaacagggtt taatatgaat gaaacgaaaa
     7021 cgggaagtta tggattgaac aatatcaaag aacgagtagc tggtattggt ggaacagtaa
     7081 aaatcattag ttttaaaggt caaggtacaa gtgtagaaat caaggtccct ttgatgaagg
     7141 aggcatagat aaggatgata aaagttttat tagtagatga ccatgaaatg gtgcgcttag
     7201 gcgtctcttt ttatttatct attcaagaag acattgaagt aattggagaa gctgaaaatg
     7261 gacgacaagg ctatgagaag gcgatgacac ttcgaccgga cgtcatttta atggacttag
     7321 tcatggaaga aatggatggt atcgaatcaa caaaagcaat cttaaaagat tggccagaag
     7381 ctaaaatcat tatcgtaacc agttttattg atgacgaaaa agtttatcct gccattgaag
     7441 caggtgcagc agggtatttg ttgaagacct ctaccgcaca tgaaattgct gatgctataa
     7501 gggcaacgca acgtggcgag cgagtattag aaccagaagt gacaacaaaa atgatggaaa
     7561 aaatgagtcg gcgaaatgag cctgtattac atgaagaact aacgaatcgg gaaaatgaaa
     7621 ttttaatgct gatttctgaa ggaaaaagta atcaggaaat agcggacgaa ttgtttatta
     7681 cactgaaaac agtaaaaaca catgtttcca atatattggc taagctagaa gtggaagacc
     7741 gtacacaagc cgctatctat gcattcaaac atggtttggt gaaataaaaa cgatgataaa
     7801 gaggataatc aaaagctgag aaaataacta ttatttttct tggctttttt acaataatga
     7861 tgcttgcttt tgtttttgta aaggctttgt tatactgaga aaagaagata ctaaaggagg
     7921 aaaacggtga aacaaaattt tgcaattgta ggtcttggac gatttggcgg aagtatctgc
     7981 cgaacactga tcgaagctgg tcaagaagta ctggctattg atagtaatga agatcgggtc
     8041 aatgaatata tgaatatagc cactcatgct gttgtggcaa atgcacagga tgaaatgaca
     8101 cttcgatcat taggcataag aaatttcgat catgtaattg tcgctattgg agaagatatt
     8161 caagccagta tcttagttac tctgatggta aaggaaatgg gcgtaccaaa tattttagca
     8221 aaagcccaaa atgagtatca tgccagagta cttgaaaaga tcggagctga tcgcgtcgtc
     8281 catcccgagc gagacatggg aataaggatt gcgcataatt tagtgtcaaa gaatatttta
     8341 gattacctag agttgtcaga taaatattct ttagcagaaa tccgagtctc caatcctaaa
     8401 tttttcaaca aaacattagc tgaattaaat ttcaggcaac gttttgactt aacagtagtc
     8461 gccatacgaa gagtagatca aacggttatc gcttctcctg cagcagatga atatgttcgt
     8521 gaaaatgata atctactggt tattggagag acaggcgatg tggatattct agacgataag
     8581 atgaatcaat agaaagaaaa gagaaagtag gttgttggga tgaaattaac ggtaacgcca
     8641 aaagcacaaa agtggtttga ctcagaaatt gatctgccag aaacttacgg aatacgtttt
     8701 tttggaaaag tctacggcaa aacagaggtt catgatggtt tttcgattgg aatgtcagtt
     8761 gaacagccag aacatcctgt aaagaaagtg gaaattgatg ggacactttt ttttatcgag
     8821 gaagcagatg aatggttctt taaaggatat gatttacttg ttgattatga tcccaacctg
     8881 gaggagccaa cctatcactt taaaaaacaa taaaaaaaga gagggtgaca caatttttgt
     8941 caccttctct tttttctttt gaaaatattg ttttcagcta ttaatatcct gcagacaatt
     9001 ttacttgatt ggtttgaagc tcatgggtgg caaagtagct tttcagattg gttaaaaaaa
     9061 tagccattaa tttcttttga aaatcaggtg tcaaacctgc aatgtgggaa gtaatcagta
     9121 cattgtccat tttccaaaga ggatgatctt gtggaagagg ctcttcctca aaaacgtcta
     9181 atgctgcaaa ggaaagttgc tggttattta aagcctgcac cagatcttgt gtcttaacag
     9241 aagcaccacg gccaacattg atgaatacag attttggatc aaagtgttca aacatatgct
     9301 gatcaaagag cccagttgtt tcctccgtta gaggtaagat attgactacg aaatctactt
     9361 caggaagaac ttcctttagt tgatttaaag aaaaagtctt ttccattcct tctgctggat
     9421 gaccggatgt attgattcca tagcagttca tgtctaatgc tttgcatttt tttgcaatca
     9481 tttttccaat atggccagtt ccaatgatta gtattttttt cccttggata gattggtaat
     9541 ggaccgatga acctaaccat ttcatgtcac tctgtgcctt ttgtgcttga aaaagaccac
     9601 gagaataccc aaggatgatt cctaagacat gctccgtaat cgattcactg tggatgccac
     9661 taccatttga aagtaaaata tgtttctttg aaaaagtctc aaggggtagc tgatcaacac
     9721 cagctgagat agattggacc catttcaagg tagaagaggc taatagtttt tcttggtagt
     9781 ctgagttcca gcccaaactg atctctacat tttgtagatc ctctggttgt aattctgttt
     9841 taaagatata accaggcgct atagtatgga tttcttcgat aaattcatca cgaaatggac
     9901 gatctgcata aatgattctt tctgacatag ttaatttccc gcctttcttt actctaagtg
     9961 tagcgcatac aagaagaact ttgaagcgcc ttgcttgttt tttgagaaag aaatattttt
    10021 caaataaaaa aggggctgtg acaaaaaaat gtcacaacct ctaaaagggt ctattgaagt
    10081 agaaataacg agttgtcttt atttcttaat tgatcgatat ttttgcccat cctttgacag
    10141 cttgagcaaa aataaagatt cctgcaaaag caatgaaggc gctagtgtca aaagaaggaa
    10201 gaaagaccat caagattgtt gcaattatag taggcaatga aattgaatag atcaatgttt
    10261 ttaaacaatc aagaaaagta gcttttgtta gtcgaaagcg tgcatagaga aaagcagcaa
    10321 tgttggtaaa tagcaaagtg atcagcagat tcagaaaact aggataaata gaaaatataa
    10381 atgtcaggac ttttatccaa agtggtatag atgcttcact taaaaaagaa cggagctgct
    10441 tacctgttaa gttttttaaa gattcattgg tgtagggaag ttctaattgg ttattgttca
    10501 acaaagcaga agtcgtgcct gtattaggaa gagctatgat aagtttgttt tttaacatcc
    10561 cgacactaac aaaattcccc atcaaatcag tagagatgtc ctgttctgtt cgttttccct
    10621 ctggatcaaa tgtgaagata atggagtttg tttggtaaat gaatccttct ttttcttcgg
    10681 tttgaagctg cccgttttgg attgtaaaat caggaatgcg agtagcaatc ttttgcccat
    10741 ccaattgaat gttgtttaag acttgaaaaa cttgaaaaga gattggcaaa gccataatta
    10801 tactcaaaac taaaagatag acaatggctt tccaaaatgg gacatttctc gcctccttta
    10861 ggtctttgaa tcgtataaag gaactgataa ttaattgttt tgttgtcata agtactcctc
    10921 atctagtagt gtcatcactt gcaattctag cgaagtatca agtgaaatac aagtgcttta
    10981 aggaaacagc tgaatgattg gtgaaatatc aaaaaaatgt tattcttgtc taaagactat
    11041 ccaatataaa taaaatggag gaaggaatag tgcctacaca gccacagaga tcatcaaaaa
    11101 aactatttgg agtagtggtt ttgaatgcgg tgatcacttt atcagaattt attggaggga
    11161 ttatgtcagg gagtttgtct cttgtttcag atgctttcca taaccttagt gatacattgg
    11221 caattatttt ttcttacggg gcacaaaaaa tggcccgaaa agaagcaaat aaaaaacgta
    11281 cgtatggcta ccagcgttta gaaatattga gtgctttcat caactcattc atattgatca
    11341 tattatcctt gtttttaacc gttgaagcat tcaagcggtt cacttcacca gaaaagataa
    11401 atagtcattt gatgctaaca gtagcagtta ttggattgct cgcgaatttg ttctcagtat
    11461 tattattacg acaagaagca gatgaaagtt tgaatataaa atctagttat ttgcatttgt
    11521 taagtgatac actgtcttcg gtaagtgtga ttatcggagc aattttgatc cgttttttcg
    11581 atatctactg gatcgatcca gttattacac tgatcatttc gatatatata ttgatagaag
    11641 cgataatggt gatcaaaaaa gctgccgcta ttttgataca aagtgcacct gctatcgact
    11701 atgaaaaaat ggaacaagaa attgaagcaa tcgatggggt aaaggatgtt catcatgtcc
    11761 atatttggca gtatagcgaa aagataatta ttttcgacgg acatattgat tttgaagatc
    11821 agctactaag cgagattgaa aagatatatc ctcgtataat ttctttatta aaattaaaat
    11881 atggtattac acatgtgacg atccaagcag agacaaaggc aaaggatcaa aaaaaattaa
    11941 tttttttaaa taaagatgaa agttattgaa atatagagta tgataaataa gaatttttaa
    12001 taaggtaggt tggctcatga agcagtatcg acagttaaaa ggatatttag aagcaaaagg
    12061 atattgggag atactagtct atctcttttt tggtggtttg gctacgattg taaattttgt
    12121 tagttttgct ctcgcacgcc aatattttga tttaagtatg gccttatcca attctatttc
    12181 gtggttttgt tctgtattgt ttgcttttgt aacgaacaaa ctttgggtat tccattcaaa
    12241 atcaccgaat tttacacatg cacttattga atgcggtaag ttcttcttct accgtatcct
    12301 ttcttacgga ttggacatgg gggcaatggt attgttgatc aatgttatga acagcaatga
    12361 gtatgtggcg aaaatcatca ctcaaattat tgttatcctt gcgaactata ttttcagcaa
    12421 gttgtttatt tttaaagaaa ctgaggtttt tgaagaagaa gtaggtcaaa gtgaaaaaga
    12481 cgactaggca taacaattga agaatttcct tctctttgtt actctttgta atgtagacat
    12541 tattaagaaa acattgagga ggaatttttt tatgacttac acattaccag atctacctta
    12601 tgcatatgac gcattggaac cttatattga cgaagaaacg atgcatctgc atcatgataa
    12661 gcatcacaat acttatgtga cgaatttaaa ttcagcaatt gagaaatacc cagaattagg
    12721 cgaaaaaaca atagaagaat tattatctga tatggacgct attccaacag atatcaagac
    12781 agctgtacgt aacaatggtg gcggacatgc taaccattca tttttctggg aaatcatggc
    12841 accaaatgct ggtggcgaac ctacaggaga aataaaagaa gcgattaatg aagcttttgg
    12901 tgatttttct tcttttaaag aagaattcaa aaaagcagcc gctggacgat ttggttctgg
    12961 atgggcttgg cttgtaatgg aaaatggaaa attagctatt acctctactg caaatcaaga
    13021 ttctccattg atggaaggaa agacaccaat tctaggtttg gacgtttggg aacatgctta
    13081 ttatttgaaa tataaaaatg tccgaccaga ttatattgca gcattctgga atgttattaa
    13141 ttgggatgaa gtaaacaaac gtttcgaagc agcaaaataa ccatttcctc cgtcatatca
    13201 gtcttaaaaa taatttggaa aataaaagag cgaaagcttg ctagcgtttt ctaaattggg
    13261 tataatgttc ttgcaaggtt acttgcaaga acttttttgg aggatataca tttatggaac
    13321 acggaacggt taaatggttc aacaatgaaa aaggatttgg gtttattaca gtagacggcg
    13381 gagatgacgt atttgttcat ttctcagcaa ttcaaggaga cggcttcaag agcctagaag
    13441 aaggtcaaga agtagaattc acgattgttg aaggtgcacg cggacctcaa gctgctgaag
    13501 tgactaaatt ataataattt gttgaataaa ga
//
LOCUS       DBBGSZ010000057        13381 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.059, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000057 DBBGSZ010000000
VERSION     DBBGSZ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.059"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(46..1365)
                     /locus_tag="ACIZE5_002467"
     CDS             complement(46..1365)
                     /locus_tag="ACIZE5_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC6109576.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1362..2015)
                     /locus_tag="ACIZE5_002468"
     CDS             complement(1362..2015)
                     /locus_tag="ACIZE5_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC6109577.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2303..2823
                     /locus_tag="ACIZE5_002469"
                     /pseudo
     CDS             2303..2823
                     /locus_tag="ACIZE5_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(2821..3540)
                     /locus_tag="ACIZE5_002470"
                     /pseudo
     CDS             complement(2821..3540)
                     /locus_tag="ACIZE5_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010745868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
     gene            complement(3491..3700)
                     /locus_tag="ACIZE5_002471"
     CDS             complement(3491..3700)
                     /locus_tag="ACIZE5_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109578.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            complement(3682..3750)
                     /locus_tag="ACIZE5_002472"
                     /pseudo
     CDS             complement(3682..3750)
                     /locus_tag="ACIZE5_002472"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
     gene            3977..5250
                     /locus_tag="ACIZE5_002473"
                     /pseudo
     CDS             3977..5250
                     /locus_tag="ACIZE5_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5357..6388)
                     /locus_tag="ACIZE5_002474"
     CDS             complement(5357..6388)
                     /locus_tag="ACIZE5_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6109579.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(6395..7225)
                     /locus_tag="ACIZE5_002475"
     CDS             complement(6395..7225)
                     /locus_tag="ACIZE5_002475"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6109580.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(7222..8037)
                     /locus_tag="ACIZE5_002476"
     CDS             complement(7222..8037)
                     /locus_tag="ACIZE5_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6109581.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(8034..8858)
                     /locus_tag="ACIZE5_002477"
     CDS             complement(8034..8858)
                     /locus_tag="ACIZE5_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HGC6109582.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(8848..9948)
                     /locus_tag="ACIZE5_002478"
     CDS             complement(8848..9948)
                     /locus_tag="ACIZE5_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGC6109583.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            10126..10911
                     /locus_tag="ACIZE5_002479"
     CDS             10126..10911
                     /locus_tag="ACIZE5_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HGC6109584.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            10944..11327
                     /locus_tag="ACIZE5_002480"
     CDS             10944..11327
                     /locus_tag="ACIZE5_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HGC6109585.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            11403..11534
                     /locus_tag="ACIZE5_002481"
     CDS             11403..11534
                     /locus_tag="ACIZE5_002481"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGC6109586.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            11503..11739
                     /locus_tag="ACIZE5_002482"
     CDS             11503..11739
                     /locus_tag="ACIZE5_002482"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGC6109587.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            11751..11837
                     /locus_tag="ACIZE5_002483"
                     /pseudo
     CDS             11751..11837
                     /locus_tag="ACIZE5_002483"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
     gene            complement(11817..12788)
                     /locus_tag="ACIZE5_002484"
     CDS             complement(11817..12788)
                     /locus_tag="ACIZE5_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HGC6109588.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT         4068 a         2917 c         2312 g         4084 t
ORIGIN      
        1 aataagtctc tatttttcaa taactattgc aaaattatat cttaattaag aaaatatttt
       61 tattttaaag ataaaaaatt cttcatcctg caatacttta tattctatat tgtaattatt
      121 cagaatatta cttacaatat ataaacctaa tccattacta ttttccttat ttaaatcaaa
      181 tttaacatca aatattttat ccatattcga aattttattg ttaccgtatg aattctctat
      241 atataaccaa tcattaacta tcccaatatt aattacccca tttacatcag tatattttac
      301 cgcattacta atcaaattag atagaataat ctttaaagct gtttttccta tataaacatt
      361 ctcgtctaat atataattat tgacagttat tttcttttga tttgctaata tttcatactt
      421 ttttaatatg tcttctaatg tatcatttat tttcaaatat tcttcatcat tattcaaatt
      481 ttctatagaa tgaactgata atatttgaga aatatttttt gttaaactat caacgatttc
      541 aatacattca ttaatataaa tatctctttc tttatatttt ccaatattgt atttcatgtt
      601 ttccagtatt attttaagac tagcaagagg ggttttaagt tcatgggatg cacctttaaa
      661 aaagtcatat tttaactttt ctaattttaa aatttcttta tttttaaatt ccaaatcgtc
      721 aattgttctt aataaagtag aatacaaatc attaatttgt tgttttaatt ctccaacttc
      781 atcattagag ctaactttta aactcatttt tttatcaagt ttcatcattt tatcagtaac
      841 aatttttatt tcttgtatat tattttttat tgattttgca taaattaaag aaataatagc
      901 agaaaataaa attgatatta ataaagaata tggtaaaaat ttaaggctta aatctttcgc
      961 atctttttgc atatcagctg tagaaacaaa ttgtagattt gtttttttac catcattaag
     1021 ctttatttct ctttcttcaa ttatcaaaga attactatca ctttctaaat taacatttat
     1081 attatctttg atttgtattt cattcttatt atttttttct tttatgaata cttttatttc
     1141 actactcttg gaataaaact ccaaagtttg ttctatatat tttatttctt ttccattcat
     1201 attactagaa atttcatttg ccatattatg aatcttttct tttctcgtct ccaaatatgt
     1261 tttaggaaag ataaaaaaaa ttaatgaatg aactaatata attattattc caagaacaga
     1321 aaatatttgt atgaacattt ttggaaatat ctttaatttt ttcattttct ctccaattta
     1381 tatcctacat ttcttatagt agttatacag tctaattgta atttttttct aagttctttt
     1441 atatatacat ctattactcg atcataagga gtttcttcgc tatctttcca tacataatca
     1501 ataatttgca ttcttgttaa cacttgtcca ttattatcca ataaacattt taatacttct
     1561 agttcttttg catttacatc tatttcttca ccatttattt tagctgtata gctattaaaa
     1621 ttaaccgata gatccttata ttcaaacttc tctaaatgtc cataattctt cttaattaaa
     1681 gaatctattc tagcttttaa gaccggcaat gaaaatggct tttctacata tccgtctact
     1741 aaattagtaa atgcatcaat tttatattct tcatcactaa atgcagtcaa gattagaatt
     1801 ggtaaattgc ttttctttct aatttctttc aacacttcta aaccatttat aaaaggtatc
     1861 tgaatgtcta agataaccaa atttatatcg ctattaaatt ttgacaaggc ttctcttcca
     1921 tctttagctt gaataacagt atatccaaat tctgaaagat attcacttat tccctctctt
     1981 atcatattat catcttcaac agttaatatt ttcatatata cctccactta agcctataca
     2041 ctagatatta tacagcatat tatggctcta taatatctag tgttggtgac gccttctgtt
     2101 gccaatactt tttctttttt ttaataaatg caaacagaca ccttgaaatc ctttagaaaa
     2161 aaggcttcta taatattttg tgttgttgga aaatcgaagg cgattttcta ctaacacttt
     2221 ttcttcgttt caactcaaaa agagactcac ttttggtaaa atttagtcga ccaaaacatc
     2281 accctaccaa aggagtcgct ctatggataa tcatactaga aaattactcg gattaacaga
     2341 taaacattta ttttttgatg aagaatggct gattgaaaaa gaatataaag gcgttcaagc
     2401 gcagtttatt aaagggagat tggatgactc accttcccat tgtgaacact gtggatcgat
     2461 tcgtattatc cgcaacggtt cctatacgac acgtactcag atgttgaaag tcaaagaaaa
     2521 gttgactatt ttagaattaa aacgtacccg ttttctatgc tatgattgtg ggcagacctt
     2581 ttctgcgaaa acggacttag ttgatgaaca tcatcaacta acaaaggaac tgaaacaggc
     2641 gattctcata gaactgtacg aaaatcaatc acgtaatctg aaaatcagaa gaagtaccgt
     2701 cggctcaagc gatattggaa actcttactc aaagattcca cgacattgga gccgctcaaa
     2761 cggcattatc atcgactgtt taaacgacca attagtcaaa cagaaatcgt cgatgaaccg
     2821 ttgtgcacaa tggtgtcctg aacgtacagc gacaccttcc atatccagag cagtcgccac
     2881 atcacgggga tggatgccat ccaaattaaa agcaaccacg ccagtatgat gttcaggatc
     2941 ttgcggtccg taaatggtga taccgccgat cgcttgtaat ttaggtaaaa cgtaggcaac
     3001 cagttcttgc tcataacgat gaatattctc cataccaatc tcattcaagt aatcgattgc
     3061 tcctgcaatg ttcggagtac cagcttcaaa tttccatggc agctctttcc atgaactatc
     3121 gtaaagattg acaaaatcta tcatttcacc gccgaattcg actggctcca tttgttctaa
     3181 caattgacgt ttgccatata atacaccgat tcctgtcggc ccgcacattt tatgcccgct
     3241 aaaggcgaaa aaatctgcat ccaacgcttg tacatcaact gtcatatgcg gtgctgcttg
     3301 ggcaccgact ggactatcct caactacaac agcctgttca accctcagcc gtttcaagca
     3361 caacaaataa ccttctggat ctggtttgcc gacctgaaga tcatcgatcg tcacaaagga
     3421 atcaattttt tccttaatca tcggatgtgc ttcaaaaaaa tagtctagct cccgcagttc
     3481 agaattgaga ctactccgat tttccagtgc tgctgatccg ctgctcaaaa tgttcagcat
     3541 ccactggtct cccaaccgct tgacttatcc cttcataaaa ggacagttct gctgccgtcc
     3601 caacaccttg ttgatagtct gcaaaaggaa ttttatagcc gaactgctcc agtaaatagg
     3661 cttcagtaaa tagtgatgaa tactctcgta aaacatccat tcactgtcaa tcatcgtccc
     3721 atcaaaatca aaaataagtg ctttggtcat cttctttccc ccttacccaa aacaagcaaa
     3781 agctgtgtcc tgctctctct acagtatcag cataaaaact gccgtctgaa aagtcaaagg
     3841 tgaaagaaat gtggcgctat aatttctagg actgatagta aatcattcta tcagtccttt
     3901 tgagcataaa aaaacaaaac atacagaagc tccgttagaa ttgaatcacc acaacacaat
     3961 caaaggagcg ttctgtatgc ctgatcttca tcttatcaaa ctattactag gaatcaaaga
     4021 tggaaacatt caaatcactc atgtcgagaa gaaaaaaata cattcaatca acagtatcgt
     4081 tgtttctgcc acgctcatta aaacgattca gccctgtcct cagtgtaaac aggtgaatca
     4141 acatgggctg atcgttaaga acggaaagaa aaaatcgctg gtccttctca ataagtgtgc
     4201 gaatcaacgg acttatcttg ctttggcaaa gcaacggtac ctctgtcgtg gctgtcacac
     4261 ctattttacg gcgaatacct acattgttga aaaaaactgt tttatcgcca aacaagtaca
     4321 ttataaaata ttggaggaat tgactgaaaa acaagcaatg acgacgattt ctaaacattg
     4381 cggcgtttct tggtcaaccg tttcgcgaac actcgcttct ctgctcccca tgacaaacgt
     4441 gaaaataaat tggttgcctc gctgttcatt ggtagatgaa tttcgttcat tgaaaaatca
     4501 agtcggtccc tattcttttt cttgtatgga tggcgatact gggaaattac tggatattct
     4561 tccttcacgt aagaagaaag atctcatttc ttattttatg caatttgaac gacgtgcacg
     4621 tttaaacgta aaaatactcg taacagatat gaacgcctct tatgctttgc tgataaaaga
     4681 gtgctttcct catgccaaac tcgttgtgga tcgctttcac atcgtcaagc acctcattcg
     4741 cagttttaag gatatttgac tatgagtcat gaaaagcttc gaccgaaacg atccaataca
     4801 agccaaacac tatcgacaag tgaaggcttt atctcgactt ctgatcaaac gacaggacac
     4861 gcttgtttat gataaatgga caaaatggcg taattttggt tgggcctatt taaccgaaag
     4921 tgaagtcgta gaacgtctac tttctacttc tgatgaacta cgaatagctt atgcttacta
     4981 tcaagaaatt cttcaagctt tttatgacaa agaagcggac atcttctttc agcttgtaaa
     5041 aacaatgccc aagtcggttc caagagaact gcatcatata aaaaaagcgt ttataaacta
     5101 tgaatccggc attcgtttag ccttagagtt gccttactca aatggcaaaa tagaaaatct
     5161 gcatacccac atcaaagcat tgaaacgaat agcttacggg ttaggatgag aaccagaatt
     5221 ttcttaatca atcatctgat cacttattaa acataaaaaa acatctaaag cagaaaatca
     5281 attctacctt agatgttctt atatcactct atcagtccta tttgacaaag agccagaaat
     5341 gtttgccgac tatacactag ctttgttgtg caaaatgctg agtatcaatt tccacaggga
     5401 ttgctagaat atctttcagc tgaatgtata aggcatcgct aattttctct tcccgatcgt
     5461 tcaaccgatc cactaaaatt tctttgccct ccagcgtttg aaaaacatac cgttgaatgt
     5521 tgcctaaaat aaatgattcc ttccatagaa ccggaatctt aaccccctga ggaaccggtt
     5581 caaattgaat cagctccggt cttaaataat aaatgcagcg attgccctta gcggaaaact
     5641 cgtgggtata ctgattcagc tcataccatt cgaaacgatt atagttgccg ataaattccg
     5701 caacaaatcg gctctgagga ttctgataca attctttcga ggtggaaacc tgagccaccc
     5761 gcccagcttc catcacaaaa atccgatcac tgattcgcat cgcctcttct tggtcatgag
     5821 tcacaaaaat catcgtcatc cctagcgatt gctggatagc gcgcaaatcc cgctgcagct
     5881 gttttctaat tcgggcatcc aaagcactta atggctcatc cagcagcagg actttcggtt
     5941 cagtgaccaa tgagcgagcc agtgccaccc gttgtcgttg accgccagaa agaaactgga
     6001 catttttatc tgcctgctcc gtcatatcca ccaatgatag catctcaaaa accttttcct
     6061 gaatcacctc aggactcagc ttctttacct tcaaaccaaa ggctacattt tcaaaaacag
     6121 tcatagttgg aaacaatgca tactgttgaa aaacaaagcc gatattgcga tccttcgtag
     6181 gcttatcggc aatattctca ttgtccagca caatctcacc gctctttggt tgttccaatc
     6241 ccgtgataca gcgcagcaac gtagactttc cgcacccgct gggacctagt aaagtaacca
     6301 gctcaccctt ttcaatctga atttcatcaa tagctaaaat ctgtttttca tcaaaaaaca
     6361 gattgagatc atgtatttct aaaaacattt tccgtcacaa ctcctttaag ggcttctttt
     6421 tcgactgctt ctcttccctc gtctgcttaa gggacagctg ttgcttttgt cgataagtca
     6481 gcataaaggt agttaaagca attcccacca taaacagcaa atacaaaacc atcacagcgc
     6541 tagccaaatg gccgttttcg ttcatccgcc gcagcatata gatgcgtacc gtctgaaatc
     6601 gaccgccaat caacaggttc gtcagcatgt actccccaaa aaccgaagaa aaaatcatca
     6661 gagaaactag ggtcacaccg atacggatgt ttggaaacag cacctggata ataatcgtag
     6721 acatcggggc gcccaaggtt tctgctgcat ccactaattc cttcagatta attaagcgca
     6781 tctggttgtt aagactaaga tagacaatcg gcaacgccgt aataaacaat gcacctacca
     6841 acactacaaa cattgggata ccagtttcag catacgttcg aagcaaagcc gttaccaaaa
     6901 tcactcctgg taaagcatac ggcagcagga gcagcttttc cagccaacga ttcaaacgag
     6961 ggaaatacaa atgaatccaa ataatggtgg gaatcatcaa caacagaatc gtcaccaaga
     7021 ccacacctgc taataaaagt gagcgaccca ccgcagcaat aaattccctg tccgtcagca
     7081 gctgttggaa ccattgcaag gtaaaatcac taggtaaaag cgattttgac catttagtgg
     7141 agctggcata caaaatcgtt ccaataatcg gcagcaagta atacaggaca aagcagaaca
     7201 aaatcggttt tattaacttt ttcacgtctg caccaccttg cctttctttt gaataatcaa
     7261 cattgccgtt accagcagga cacctaaagc gactgccaac gcactgccta aattaggctt
     7321 ggcgaacaca tctcccgaca ctaaagccgc aattcgaatc gttaaaagat ttacattact
     7381 gctggtcagg gcatacgctg tttcataggt ccccatgcca ttagcaaata agatgacaaa
     7441 ggtgctggca atcgatggtc gcaaaaaagg caaagccacc ttgaaccaag catacgctga
     7501 tgaagcgccc agcaattgtg cggactccag ccattccttt ttcacttcct tcatgctggg
     7561 atacaaaaac aagaccccta acggaatttg gaaataggta tacgtgatgg tcaatcccca
     7621 ccaagaatac aaattgaagt ccgctagaaa tggcaaaatc attttcagca cacctacatt
     7681 ccccaacaaa ataataaaag agaatgccag cggaatccca gcaaaattag ctgccaaatt
     7741 ggaaacaaag gtgattttct cctgcaattt agtcgataga ttcattaagc ataaacataa
     7801 aataaacgtc ccgattaacc caatcacact ggagctgaca gcaatcagta cgctgttaac
     7861 aaaggcctgt gtgtaatatt tgttgctgaa aatatcactg taattggcca atgtccactg
     7921 gttagttaaa tcactgtgca agctgcacag aaccataaaa agcagcggca gcagtaaaaa
     7981 tgcacagaag ataaaggagg caggaaccag aaccaagcgt tttttcatct ctttcatccc
     8041 ctcatcaatt cttgaatgtc ctgcattttc tctgacggtg caattcctaa taaccagcaa
     8101 aacaatggag ccgccagcag ctgtggtaca gtttgttcct tcagcttttg gcgtttattt
     8161 gaaatcaaat aaaaaggaac ttcacgatgt gcagccaagc tgccgccatg cagtccgtgc
     8221 gcatccatcc cgtgatccgc agtcaccacg acttgataac ctttttgcag ccattcagga
     8281 aggtaaatag ccaataatct gtccgcctga ttaaccgctg ctgcatattc atgagaatcg
     8341 gcggtaaatt tgtgaccgac atcatcaata ttcatcgaat gtacgaccaa aaagtctggc
     8401 tgatactgat tcactaaata atgggcatcc gcaaataaat gcgaatcagg gtaagtgtcc
     8461 tcactataaa agatgccatg ctgaatcagt cgctcctcct gatgctggat gcgatcaacc
     8521 aaacgattat agggggcttg attgtacaac tcgctgtacc agtggtaagc ggcggctcct
     8581 gtttttccgc cagcttcctt aactaattca aacagcgacc actctttgga tcgctgagca
     8641 tggtaattac tatagatgcc attttcatag gctggaacgc cggtcatcag tacttcgtat
     8701 aacggacgtg aattgctggg cagctcactt tttaccttca ataagcttgc ttgctggtgc
     8761 tcaactaaat gattcatgaa cccaagctgg gcgacggctg tgtcgtagcg acagccgtct
     8821 agtataacta caatcagttt gtcaagtcta ctttgcatag gtcagtacct ccgcctgcca
     8881 aagctctgga agctctacag aggtcttgtt ccaagcttca ttgtcttcaa ctggcaccgc
     8941 cgcttcataa gcatcctccg gcagtaattt ttcagctact tctttaggca gctctacctt
     9001 gcgaataggt cgcgcatagc cctttgccaa attgatttgc ccttcatcag ataaaatata
     9061 ttcccgtgct agctttgccg cattgggatg aggggcattt ttattgatta aggttgtata
     9121 cccgctaatg atggagccgt ctgttggcac agttacctca aaacgctcgg agtcaatttg
     9181 gtcacgataa tttagtccat tgaagtccca aacaactgcc acatcgattt cacctttttc
     9241 aagatttgct acgctggcat caacggtgga caaacggcct ttttctgcca tttttttgta
     9301 gtaattcaga cctggctgaa tatccttttc gtcacctccg ttggcaatcg ccgcagccaa
     9361 tacagcaaat tgtgcttggt tggcaatcgt cacatccccc acgctaactt gatagtcacc
     9421 ctcttgcagc tccttccagc tagtcggtgc ttgcttcaca ttctctttat cggtgataaa
     9481 ggaaatggtt cccgtatagc ttaacaacca atccccatca tcatcctttg cccaatccgg
     9541 aatttcctcc caatagttgg tcttataagg taaggttaac tctttgcttt cagccaacgg
     9601 accgaagctg ataccgacat caccaatatc ggcggttcca ttttttcctt ctgattcaaa
     9661 cttagccaat tcttctgcac tggacatatc cgtatccacg tgacttaagc cgtattcttt
     9721 ttcaaggtcg ttccaagtgc ctacccaatt tgcccaagta tccggcattc ccaagctggc
     9781 aatctctcct tcttccttgg ctttttctat aatcgtatct aaagagtcgt ctgccgcagc
     9841 cgattgcttc gttgcttcac ctgagccgca gcctgtcagc aggatactta ctgttgctgc
     9901 acaaaataaa ccgatagtca tgttacgaat tttttcattc attttcattc attcttctcc
     9961 cctttcgata attccattct aacaaagctt tgtaatgaga gaatcagttt cttgaaaagg
    10021 tttcatgaac aatgtaaagg ttgtatatgg tttgtaaatt tcgacgaatt cccgttaacc
    10081 ttctaaagct tttgcggtat gatagtagaa aaaaggaggc tccctatgca gtattatgat
    10141 cagcatctcc acacgtattt ttcctttgat tcagaggaaa aatttgaaaa ctatttagcc
    10201 tatcagccgg agtttttcgt ttctacggat cactttgatt taaacaatcc atctaccgga
    10261 aaagatgaca ttccggatta tccagcctat ataaacaaac tggactcttt aaaagaaacc
    10321 tattccacca aatttctgcg aggtatcgag attggcgttg ttccaggaca agaagagcgg
    10381 atcgtggatt acctcgctca gcatccttat gatttaaagc tggtaagtat tcatcaaaat
    10441 ggccgctttg attatatgga cgatgtggtt ttaaccaaag atcccattca aactaccaag
    10501 gaatattttg atcagatgtt gcaggtcttg acggattttc cagaaggaga tattttgact
    10561 cactttgatt atggattacg ccgcttcacc ttcacagcgg aagaattcgc ggagcatttt
    10621 gaggctcagc tgctaacgat tttcaaaaag gttgttgaac gagaattggc gatggagtta
    10681 aatgccaaga gcttcttgaa atacggcaac gaagaccttt accgttatgc cgttcctttg
    10741 tatcaaagtg tcggcggaaa gctctttacc ttaggctcgg atgctcatgt tgccgaagat
    10801 tatcagctgg gctttaaaaa aatgagtcag ctgttggcag actgtcaggt agaaaagttg
    10861 ctagtcattc aaggaaaaga acgccgcctg acgccgctgc cgattttgtg attcctatat
    10921 aatagaagaa agtggtgaaa aaaatgagca acctgtggga ctacaatcaa gaggcaccca
    10981 tccattattt aattgcgcga cattgggatg cgttgaaaat tgaggcggtt tgccgatcct
    11041 tgttagcagc cgttccaaaa caacaactgg aaaatttttt ggtggctgac agcttgcagc
    11101 gggaaaaagt tcaggcttat tttgcagcct ttaaagatca gcctttggaa tatttgcatg
    11161 cgcagtttca tcttttttat caagtagccg ccccagatga ctacaacgat ttacgaggac
    11221 agctgcaatt gacctttcaa gcggatgaaa ccgcctatac cgttttattg ggaatggctc
    11281 gccttggtga tcaggcgaag gtcgagtggc ggattttcga tatttgatgg caggatcaag
    11341 gcgtttcagt tgcaaacctt cctctctttc aattagaaaa accgcagcag gaagaagttt
    11401 gtgtgctggt caccgatgct ggtgaaattc gtctccgctt atttcctgac caagctcccc
    11461 tggctgtagc caactggcgc tccctagctg agcaaggcgt ttatgacaac acacctttcg
    11521 gctcgtgtca ttaaggaatt tgttattcaa ggtggcgctt tggatggttc tggtgatgaa
    11581 gctgtttcca gctatgaggg ctttttcgct gatgaagtgc atcgcggact ttatcatttt
    11641 aatggcgcct tggccttagg ggaccacggc ccccacacca acggcaacca gttttttatt
    11701 gtgcaaaaca caaaggcgca ggctgacctg ctaatgtaaa gcaagcatac ttggagcttg
    11761 gaggactacc ggagctggat ggtcgttata ctgtttttgg acaggtatac caagggttag
    11821 aaatcgtagc agcgatcgca gctcagccga caaacagtga agatgtaccg attgagccag
    11881 tgttcattcg acaaattaac ttcgaaaaaa catcgtaaaa agacactcac tgacttcagc
    11941 aaaagctcta ttcttgagct ggctgcagct agtgagtgtc tttcatttat ccataagata
    12001 aagcttggat tcaataaata aataaatgtt ttggttaaag ctgtgaccag caaatgagga
    12061 accgtgcgag ccagttgatc tgccaatgca aacatttctt taggtgaagg cgctggcgtg
    12121 tctgccaacg gatactccag tcccaatgct tggtaaccgt gcataccata gcagtggtac
    12181 ggtagtaatt ctaacggtac gaaccgatca agatctgcca caaaacaagc aatcgtcagc
    12241 agctcggtca ggttcatatt gatacctgga accacaggaa ctcgaattcg cacttcgcag
    12301 ttaggatact caattaaaaa gcgacgaata ttcttcaaaa tttgttggtt atctaagccg
    12361 gtccattgtt tgtggagctt gctggtaaac atttttacat ccacaaacaa tgtatccaca
    12421 tagggagcta ccttttggat ttcattataa gcaccacaaa agctggtttc cagtacggta
    12481 ttgattccaa tgtatttcga tttttgcaaa atttctttag caaaatccgc ctgaaccagt
    12541 gcctcgcctc cgctaatggt cactccgcca tccgagtgaa agtaaaaaac agcatccttc
    12601 tcaatctcat ccattacctc ttcagcggtc atggtctggc caaatccttt ttcaatctgc
    12661 ttgctttgtg attcgggaat cgaacaccag gcacagcgta atgggcagcc ctttaaataa
    12721 acaacggtcc gtaaaccagc accatcatgt agagaaccct gttctattct taatactgtt
    12781 ccttccatat agatttttga attacacact agtttaaact aaaacacaca aggaaaaact
    12841 taccatttaa tcataaaatt agctcatata aatatactag gatgtaaaat agactggtca
    12901 aaatctggtc aaaaaagagg actaatacag gtagtcctct tttttgttat tttaatattc
    12961 taaatcattt tttattggtt tattccctta ttcgatgtag actcaaatca ctatatcact
    13021 agatatcaaa cggcgtcata cggaatcaaa aacatcaaat ttgacctgtt aaatggtcat
    13081 tgaataacat tcaaaatcaa taaaacggag tcagacacgg agtcaaaaac gctgagagta
    13141 aaaaatatat acagccttgt aggtaaagta ccacagggct gtatattttt tatttcagat
    13201 taccttaaat gattccattt actttttatc tcattttttc ctactagtta gtatcaaata
    13261 ctctcctatt ttctcaataa actatttttg gatacatggt atctgaaaca gctaaaacct
    13321 tgtcattaca gcaaaaaatc acgttatcca gactgtagac aaagtccatt ttatggatga
    13381 t
//
LOCUS       DBBGSZ010000058        13084 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.061, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000058 DBBGSZ010000000
VERSION     DBBGSZ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13084
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.061"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(78..2198)
                     /locus_tag="ACIZE5_002485"
     CDS             complement(78..2198)
                     /locus_tag="ACIZE5_002485"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HGC6109589.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2428..3606
                     /locus_tag="ACIZE5_002486"
     CDS             2428..3606
                     /locus_tag="ACIZE5_002486"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HGC6109590.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3622..4380
                     /gene="aroD"
                     /locus_tag="ACIZE5_002487"
     CDS             3622..4380
                     /gene="aroD"
                     /locus_tag="ACIZE5_002487"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HGC6109591.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4403..4888
                     /gene="ybaK"
                     /locus_tag="ACIZE5_002488"
     CDS             4403..4888
                     /gene="ybaK"
                     /locus_tag="ACIZE5_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HGC6109592.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4959..6212)
                     /locus_tag="ACIZE5_002489"
     CDS             complement(4959..6212)
                     /locus_tag="ACIZE5_002489"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGC6109593.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6328..7677
                     /gene="gdhA"
                     /locus_tag="ACIZE5_002490"
     CDS             6328..7677
                     /gene="gdhA"
                     /locus_tag="ACIZE5_002490"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HGC6109594.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7789..9135
                     /locus_tag="ACIZE5_002491"
     CDS             7789..9135
                     /locus_tag="ACIZE5_002491"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HGC6109595.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9443..9829)
                     /locus_tag="ACIZE5_002492"
     CDS             complement(9443..9829)
                     /locus_tag="ACIZE5_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HGC6109596.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(10097..10246)
                     /locus_tag="ACIZE5_002493"
     CDS             complement(10097..10246)
                     /locus_tag="ACIZE5_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109597.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            10708..10920
                     /locus_tag="ACIZE5_002494"
     CDS             10708..10920
                     /locus_tag="ACIZE5_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109598.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(11198..12997)
                     /locus_tag="ACIZE5_002495"
     CDS             complement(11198..12997)
                     /locus_tag="ACIZE5_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HGC6109599.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRSFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT         4291 a         2353 c         2577 g         3863 t
ORIGIN      
        1 tattctaaga tttctcttta ccaacatcat ttgacaaaga gcctaatttt gtcgctgctc
       61 cttttaaatt tattttatca ttcggaagaa cttgtggtcg ttccgtgaag ttcttggtac
      121 gtttgcgttt tataaagatc aacagttgat tgtcccttgt gttcactaaa gacactagtt
      181 gacttgtcac caagagattt ttcagcttct tttaatttct ctaagccatt cttgtagtca
      241 taatcactgg tatcaattgg gtctaatcca ctattcgtat agaaccgaag aagatcacca
      301 ttattgattt ggtcagaaac agctaactgt ttatcaactt tttctttcag tgaatcaatt
      361 tcattctgta cttcctcagt aggttcagta atagcttcac cagtttcgtt actatagatc
      421 gtaccaccgt agtaagtata ttttggtgta acaaaatcac catcacggaa agaaacaagc
      481 tgttcatgat ctttcgagaa tagatcttgt cctaactgaa tataattttt tgtatctaca
      541 cctagtaagt gaagtaatgt aggcaaggca tcaacttgtc cgccgtaagt gtgattgatt
      601 ccgccctgtg tttgtccagg gatatggatc atataaggga cacgctgcat ttgtgcattg
      661 tcgtagtttg tccaagtaga acttgttttt ccaactaatt cagctagatt tttatttctt
      721 gaattcgaga caccgtaatg gtcaccgtaa aggacgatga ctgaattatc atacaagccg
      781 ctttctttca aataattgaa gaattcttgt acggcggtat ctaaataatt ggctgtcgca
      841 aagtaaccgt tgatcgtttc atcatttgta ttggctaacg ggaatcctgc ttcgtcattg
      901 gtgaattttg aataaggata atggttagat acagcaatga attttgaata aaatggttgt
      961 tgcagacgtt ccaagtattg tacggattgt tggaaaaatg gtttatcatg caacccgtat
     1021 tggaacgaat tgtcatcatt aacatcataa taagaagaat caaagaaata atcatatcct
     1081 aaattcttgt atgtctcgtt tcgattccag aatgtaccag cgttcccatg gaataccgca
     1141 ctagtgtaac cttgtgtttg acttaaaata tcaggtgcag cttggaaagt attttttccg
     1201 cctaattgtg tgaacaagga gccttgattc aagccaaaca atgaattttc catcagcgtt
     1261 tccgcatcgc ttgtttttcc tgcttttact tgatggaaaa agttgtcaaa actgaacgtg
     1321 ctgttgctgt ggtaaagact attgatgaaa ggtgtaactt caagctggag accattctca
     1381 tctgtcaatt tataatcgat caggaattgc tggaagcttt ctaaatggat ataaatcaca
     1441 ttttttcctt tagcgagccc gaacaaatca tcatttggtg ctgcataatg ttcttttaca
     1501 taattttcta cttctttcat atcattggga cttgcttctg cccgcacttg gtttgtctgg
     1561 taagtttgaa caccgtcata aaccatgaaa gcattcaagc caagatattt gaccaaataa
     1621 tcacgagaga atgttcgagt cagcaattct ggacgatcag cttccgccat aaaaagattt
     1681 cctgagaaaa tcataactgc taatgtagag atcgcaaaag ccattcttgc tcggatcggg
     1741 cgagggtcca acttgatttt ttttgcaatc agcagaacag tcaagataat aaaatcgatc
     1801 caatagatca catcatatgg gcgaaacagt cgaatggcac tttctcccag accactcgct
     1861 actttcccag cacctaaaat cgtgttgatc gtaatgaagt ccgtgaattc tcgataataa
     1921 gtgacattcg aaaaaacaag caatgtcaaa agaaaataaa tgaccatcat cgtgatataa
     1981 gcaactctag ggcgtctgat ataaagagca attccaagta ataacaatgt agttgcaata
     2041 gggttgataa acaagataaa gtattgaatg ccactttcga ttccgagatg gaaatcaact
     2101 aaataggcaa aaatcgtttt caaccaaagt aaaacaacta gtaaagaaaa aaatccgagc
     2161 ctcttattca aaaaggcagg tgtttttata catttcaaga taatcttcct ttctgcactt
     2221 cttaatcaca gaagtgtcat gaaaccatgt tacacagctc acttattctc atttatttta
     2281 ctagtatgac aatatagtgt caattgaaac cagaagttta tgctgtttca ttaaggtttt
     2341 ctttaagctt catgaaaaaa tgagcagtaa gacaagtcct atgttttttg ttatacttgg
     2401 gaagagaaag ctaaagcagg tgaaggaatg aaagtaaaag taaaaaaaag agcaagcaat
     2461 cgattgaaaa aaggatatcc actgatccaa aaagaagacc ttgctcatcc ccaaaaagaa
     2521 accacgcaat gggtggaatt agttgattcg caaaaccaat ttatcgcaaa aggatatcta
     2581 ggaaagcaga ataagggaat cggttgggta ttgagccagc agaacatccc atttgatcaa
     2641 tctttttttg aagaattttt tgtgaagtca aaagaaaaaa gaactttctt tttttcagat
     2701 gattctacta ccgcttttcg tatattcaat ggagaaggag acgggatcgg cggtctgatt
     2761 gttgattatt atgcaggtta tgctgttttt tcttggtata acgaaacgtt atatgcacat
     2821 cgtgaattat tgattcaagc ttttcgtgaa atctacccgg aaatcgtagg aggctatgag
     2881 aaaattcgat ttgaatcagt aaatctgcct gagagccagt tcatttacgg aaaagaggca
     2941 ccggaaccct tgatcgtaaa agaaaacgga gtaaaatttg ccgtttattt aaatgaagga
     3001 ttaatgactg ggatcttttt agaccaaaaa gaagtacggg gatcattagc agaaggtttc
     3061 gcttctggga aaacagtttt gaacatgttt agttataccg gcgccttttc tgttgctgcc
     3121 gcaatgggag gggcaatcga aacaacaagt gtcgatctag caaaacgcag tttaaaaaaa
     3181 acacaggaac agtttgaagt gaatggtttg gatgtcgatc agcaaaaaat cattgttatg
     3241 gacgtattcg agtatttcaa atacgccaaa agaaaacaat ttttatatga catgattgta
     3301 ttggatccac caagttttgc cagaaataag aaaaaagtct ttcgcgtagc aaaagattat
     3361 ggggaactgg tcaaggatag tctggatatt ttagcagaag acgggatact tattgcgtct
     3421 acaaatgctg cgaatgtctc gatagaacaa ttccaaacaa tgattgaaga ggaattccat
     3481 gccaaaaatg tttcttttga acaacttgct ttatatcgtc tgccaaaaga tttccagacg
     3541 acggatacct ttttagaagg caattatctg aaagtgtttg tttatcaaat taaaaataac
     3601 cattagaagg agcgatgcag aatggtttgg gtaaagggat tgaatatagg aagcggtaga
     3661 ccaaagattt gtgcgcctct tatcggggcc gtccgagagg aagtattacg tgaagcagtt
     3721 cttgcacgtg aagcaggggc cgatttagtc gaatggcgag tcgatcatta tcgtgaagtt
     3781 ttttcttttg atgaagtagc agaaacattg gttcttatcc atgagatgct tgatggactg
     3841 ccgttattat ttacgtttcg taccttagct gaaggcggag aacaagacat atcgatccgt
     3901 cagtatcgcg acctttatga acatgtgata cacacaggat tagtagatat ggtcgatatc
     3961 gagttgttca aagtagaaag tctaggaaaa agactgatag aggaaatcaa gtctttaaac
     4021 attcctttaa ttatcagtag tcatgatttt aaagaaacac cagcagaccc tgtcttgctt
     4081 taccgattga atgttatgga acattttgga gccgatatcg gaaaactggc agtaactccc
     4141 aataatgaac gagatgtttt gcggttgatg gagttgacta gacgggcaaa tgcttttgtc
     4201 tccatgccta ttattacgat gtccatggga aatcttggta aaatttctcg tctggctggc
     4261 ggaacgacgg gttccgttat gacatttggt tccttaagca gcgattctac ttctgctcca
     4321 ggacaattac cggtcaaagc attgaagcaa attattcaat tattaaatga accgttgtag
     4381 aacaagtttg aggtgatatt ttttggcaaa gaaaaaaata gtaaaaacga atgcaatccg
     4441 tatggtcgaa caaaaaaaga ttccctatac agagcacgaa tatgagtggg acgaaagcca
     4501 cctaagtgcg tcatcggtcg ctgaacagct tccagaaagc caatctcata tatttaaaac
     4561 actggttgct gtgggcaatg tgacggggcc tcttgttgct gtgataccgg gagaagccga
     4621 attgaatcta aaaaaattag caaaagtttc agggaataaa aaagtagaaa tgctccattt
     4681 aaaagatttg gaagcaacga ccggatacat acgtggtggc tgctcgccta taggtatgaa
     4741 aaaactattt cctacttatt tagatcaaat tgcagaaagc tatgaacaaa tcattgtctc
     4801 ggctggcaga agagggctac agatggagtt agcacctcaa gatatctgtg cattaacgag
     4861 cggacaattt gcagatataa aacaataaat catacgtata aaagaaagaa ggaggccggg
     4921 atgttgtttg tccagtctcc ttctttcttt tttatacatt atgctctttg cccggcattc
     4981 attcctgcta catgccctgt agcgaaagcc gctgtgatat taaagccgcc agtataacca
     5041 ttgacatcca gtaattctcc cgcaaaatac agaccatcaa tgattttact ctccaatgtt
     5101 ttaggataaa tttcctttag agaaacccct ccgccagtta caaatgattt ctcaatagga
     5161 aaagttttgt tgattgatag cttaaactct ttgcatagtt gaacaaaatc ttgaatttgt
     5221 ttttgagagg cttgttgtcc tgtcagatga tccatttcaa gccgctcaag aaagaaaact
     5281 aacaatcgct caggcaatat accatgccaa gcattgacca agttcttttt ggttgcttta
     5341 cttttttctg tcaatatatg aataagctct tgtttggttt gtgtagggaa acaatccaga
     5401 gaaagtgtca ctggttctcc cgttttctct aattctttat tgacaaaact tgaacaacgc
     5461 agtgcagccg gaccagaaat accgaaatgg gtgaaaagta aatccatcgt atgttcagtc
     5521 aatacacgac cttttttatt taaaacgcgt aaagtgatgt cttgtaaaga aagcccttga
     5581 agtgttttct cctgaatata cggttcatcc gatatcaagg gggactctgt cgcataaaga
     5641 ggcgtcaccg tgtgacccac tcgcttcacg atcttgtacc catctccagt agaaccagta
     5701 gatggataag tccgtccacc agttgttaag ataatggcag gagcatggaa ctcttcgaat
     5761 tccgtgcgta taccgtaaat tttatgttct ttgtggatca atttctctac tcgagtagag
     5821 aatagaagcg tcacatctag ttctttcaga cgattgagca atgcttcgat aatcgttttt
     5881 gatttatttg ttacaggaaa catccgtcca tgatcctctt cttttaaatg tacgccttgt
     5941 gattcaaaga agttcatgat atcgaaatta ttccattgcg caaacgtact atataaaaac
     6001 tttccatttc caggaatatg tgcaatcaaa tcatcaacag gacgattgtt cgtaacattg
     6061 caccgaccac cacctgtcat cagtagtttt tttcctgctt ttttgttttt ttcgatcaag
     6121 agtacgcgtg cgccttgttc agctgcactg atcgctgcca tcatcccgct tgttccagcg
     6181 ccgactacga tcacatcata cagtttttcc attccctcac ctcaaggaaa gtgtagcata
     6241 tctgaagaaa gaaaacagaa aaaatgtttt gagccaaaag agaaaatgag ctaaaatgag
     6301 ggaagataag caaaggagcg tggaacgatg acaaacgcaa cagaatatgt tcaagcaatt
     6361 caagaaaagc tacatcaaaa ggatcaaggg caagaagaat ttttacaagc aatcgatgaa
     6421 ttcatgccca cggttatgtc ttttttggac actcatcccg aatatatcga aaagaatatc
     6481 ttagaacttt taacggaacc agaaagagtt attcaatttc gagtgccttg gcaagatgat
     6541 gaaggaaact ggcgagtaaa tagagggtac cgtatccaat acaactcagc tatcggccct
     6601 tataaaggtg gattgcgctt ccatcctagt gtcaatctaa gtatcttgaa atttttggct
     6661 tttgaacaga ttttcaagaa tagtttaacc ggtctgccaa tcggtggagg aaaaggcgga
     6721 agtgacttcg atcctaaagg aaaatctgat aatgagatca tgcgtttttg tcaaagtttc
     6781 atgctggaat tgtcaaaaca tatcggccca tcgattgatg ttcctgcggg agatatcggt
     6841 gtaggagcta gagaaatcgg ctatttgttc ggcgaatata aacgattgaa aaaatatgat
     6901 actggtgtgt tgacaggtaa acctttggat ttttggggaa gtaagatacg tacggaagct
     6961 actggttatg gattagtgta ttatgtcaaa catctattga acgaagaaaa agattcattt
     7021 aatcaaaaaa cagtttttgt ttccggaagc gggaatgtag ccatttatgc aatcgaaaaa
     7081 gtgcaagagc taggcgggaa agttgttaca tgttcagatt ctagcgggta catctatgat
     7141 ccagaaggaa tagatgtgaa actattgaaa gaagtcaaag aaatcaatag acaacgtttg
     7201 acggaatacg caaaccaacg tccttctgct atttatcatg ctggagaatc tgtttggaca
     7261 ttgaaagaaa aagcggatat cgctttgcca tgtgctactc aaaatgaaat agacgaaagc
     7321 ttggccgaaa tcttagtaga aaatgggatc aaaatcgtag cagaaggcgc taatatgcca
     7381 tgtacagtaa aagctgtttc tgttcttcat gaagcaggcg tgtggtattg tccaggaaaa
     7441 gctgctaatg ctggaggagt agcagtatct gctttagaaa tgagtcagaa cgcccagcga
     7501 ttgacttggg aaagagagca agtggatgag cagctggatc aaatcatgga aacgatttac
     7561 catacgtgtc gccaaacagc agccgagtac ggcgacgaaa aaaatctgct tcttggagca
     7621 aatgttgctg gatttgaaaa agttgccaaa gcaatggcag cagaaggttt agtttgaaaa
     7681 atgaaacttt cttggaaata ttgtcagcat tttgtttatt tgcttgaaaa ataataaaaa
     7741 aaaacgtaaa gtattacctg tagagtaaac ctataaggag gagaacaaat ggcacacatt
     7801 cattttgact attcaaaagt agcaccgttt gtcaacgaac aagagttagg gtacatgcaa
     7861 agccaagtaa cagcagccca caacgaatta cgggaaggta ctggcgcagg aagcgacttc
     7921 cgcggctgga tcgatttacc aacgaactat gacaaagaag aatttgcacg tatcaaagaa
     7981 gcagctaaaa aaatccaatc tgattctgaa gtattagttg ttatcggtat cggtggttct
     8041 tatttaggcg ctcgtgcagc gatcgacttc ttgaatcaca cattcttcaa tttattagat
     8101 agcaacacaa gaaaagcacc acaaatcttc tttgccggaa attcaatcag ctcaacatat
     8161 attgctgact tgatcgaagt aatcggtgat cgcgactttt cagtaaacgt tatttcaaaa
     8221 tctggaacaa ctactgaacc agcgattgcg ttccgtgtat tcaaagagct tcttgttaag
     8281 aaatatggac aagaagaagc aaacaaacgt atctacgcta caacagataa agcaaaaggt
     8341 gcagttaaag tagaagcaga tgcagaaggt tgggaaactt tcgtgattcc tgatgacatc
     8401 ggcggacgtt tctctgtatt aactgctgtt ggtttgttac caatcgctgt tagtggtgca
     8461 gatatcgatg cattgatgca aggtgccgct gatgcaagca aagcatactc aagcgacaaa
     8521 ctagaagaaa acgaagctta ccaatacgca gcaatgcgca acattcttta ccgtaaaggc
     8581 aaagtaactg agttgttgat caactatgaa ccaggaatgc aatacttctc agaatggtgg
     8641 aaacaattgt atggtgaatc tgaaggaaaa gaccaaaaag gcatctatcc ttcaagcgca
     8701 aacttctcaa ctgatttgca ctctttagga caattcatcc aagaaggacg tcgcaatatt
     8761 tttgaaacag ttgtgaaggt tgaaaaacct cgtaaatcaa tcacaattcc tgaacaagca
     8821 gaagatttag acggtctagg ctacttgcaa ggaaaagaag tggacttcgt aaatacaaaa
     8881 gcatttgaag gaacattgct tgctcataca gacggtgacg tgcctaactt gctagtcaaa
     8941 attccagaaa tggatgctta tacattgggt tatacaatgt acttctttga aattgctgta
     9001 ggtatttcag gttacttgaa tggaatcaac ccattcgacc aaccaggtgt agaagcttac
     9061 aagaaaaaca tgttcgcact tctaggcaaa ccgggctttg aagatcttgc taaagaattg
     9121 aacgaacgcc tgtaagataa gggtttttcg ctagatttaa ataatcagtg atagaaacat
     9181 gttcgcttta aaatgaaaac tggtacccat ttaggtactc aaacatactg catcgtttat
     9241 tcagaataag gggctgtgac aagacgtttg tcacagtccc ttgtttgtat agaaatcgat
     9301 tgattgcctt gctctttagt ttgttttagg actttaagaa cagtgaggct gacttcgaag
     9361 gttaattctg tttttttgtt ttctagaatc agtaagcaaa aaagcactca cttcgagtgc
     9421 ttttttgcga tatattctta gcttaagata ggcctaattt ttcttttaca gatgagggta
     9481 ccttatcgct ggtaattact tttttctcta tgatccgctt ttcgcttgct ttcaactgca
     9541 agatcgttcc ttcggtgtaa gcagaaccat tggcagagtc accagaagta atgacatcga
     9601 aatctaactg tcttttttca ccgttttcag cataagcatc tacgttgtat ttaaaacctc
     9661 ttccaattac ttccccatta tctgctttga tatcagtttc tgcaggcatt ggagctttga
     9721 ctaccgcata ataatcttta cctacataag tagactgata gtagtcccaa cctttccatc
     9781 ctataaaagc aatcaatatg ataacgatca accctaaaat ttttttcatg aaagatctcc
     9841 ttttttattt ttattatatt aaatattata cagataataa cggaatatta tcatcgaaac
     9901 agctaacaaa attgtcataa aaaacgagat ggttgatatt agaacttgtg tttttgttta
     9961 ggtctagaga taaagagaga caatttccaa atatatgtaa tgaatacaaa aagacgtttg
    10021 tcgcggatta ccgttacaaa cgtcttttat tgattttccg agatctcatc agtcgccatt
    10081 tggaatggtt cactccttat ctagattcgt ttaatgctcg gactgcttgt tcgattgtaa
    10141 taccaaacgc aacgttattt tcgttttgtg catcaatcgc cataaaacgg ttagaagttg
    10201 tatcaaaagc tacgcggtat tgcatatttg tttttgtaaa cgtcataaaa ttcatctcct
    10261 ttgtaatgta atttagttct tgaaagtttc ctttaaactt tcgaacttat accaagttta
    10321 gcatcgtacg ttttttgatg caattaaaaa gcatttatca ttttccttat ttattttttc
    10381 ttaaatggtt tagctatttt cttttaatcc gataagtagc ccaatcatca aggttacaaa
    10441 tactattgct tgaatataaa tcatatgctc acctctttat aaataactta gcaatataaa
    10501 gaaaaaaacg cacgaacaac ataggaatat aaacaaacgt ttttgtcaca acgtctaaga
    10561 tcgtgttaaa aaatagttat ctaaaaagca gaaagatact caaaataaaa aataaaaaaa
    10621 tgaataaaaa cgttttcaaa tacaaggtaa tttgttatta taaaataaag aaaaaacaaa
    10681 ataaaaataa agaaaagagg gaatgaaatg gtaaaagcag aagtaggaag atcttatata
    10741 tgcaaaccga tcggagtatc tcatgaacta atcggctgta ttgaacgtac atatatcaac
    10801 acggctgtcg tgtatgttga aagttatgac caacgagact atcaacttat caatgaaagc
    10861 aagtatcgca tgctcgtaaa attctgtgat attagcgcac ctactgaatt ggtttcttaa
    10921 acagtatttt tgagaattcg caagaactcc cttataatat aaataaagac agaagggagc
    10981 gagaagatat gccaaaaaga aaaagttcag ggaaaatggg aattattctt gcagtgatct
    11041 ctgcaattcc tgctatttta gctattgttc gtgcgatgaa ggaatcaaga gaaagttaag
    11101 cacacattat gagcgtcaaa caaaaaacgc atatacctgc ggtggcaggt tatgcgtttt
    11161 ttgttgtata aagacttttt tcattaacga tttttgatta gccgactccc aaaacaaaat
    11221 ttagcagttt atctgaataa gtgatttctt catctgtttg tttcacactt tcatttagta
    11281 gtcccatctc atcggttatg ataccatcca caccataaaa catcatgcga ctcatggcat
    11341 ctgaatcgtt gattgtccat acatatactt cttttccgtc ttggtgggca gaattaatga
    11401 agttacggtt gatcgtacta tattccattg tcagaaaatc agcaggcgtc acagggggcc
    11461 caacaatatt gaaaggtaag atgtagccca cataaaagtt tggttctgct tcttttaaat
    11521 ctgaaacggt ttggtacgtc aaactttgca aaatatgatg gttctctaag ataactttgc
    11581 ggtatttatg gacaaatcgt tcgacaaggt catccgaatc ttttttagag gtcttgatct
    11641 caataagtaa tttttggttt agcttatgtg ctttttccaa ataagaatca aaagaacaaa
    11701 caggggcttg cactccgttt tcagtaactg taagatttgt caattctttc aatgtaagat
    11761 cctgtggtgt tccatttacc cctgttaagt gacgaagatt tgcatcatgc atcactacga
    11821 aatgaccatc ttttgtttcc tgaacatcca tctctacata atcaggatga tagtctctgc
    11881 ttgttttttc aagtgcttct aaagtatttt gcgccccatt ttgggtactc acacctctgt
    11941 gagagacagt cactggtttt gtctgaacag ctgaagtcag ataatccata ttgtaaagac
    12001 agacgccaat accgaaaaaa actgcaaaaa gagtcaaacc agtgtttttc agcgcagaga
    12061 aacgcaagtt gggggcttgt gggataaacc acttagggat ctcaggcaag aagccttcgt
    12121 catccatgaa atcaacaatg atataaaaaa tccctacggt agacatcacg atattgaata
    12181 ataaaatccc ttgtaaaagc gtcatagcaa acacagcgct gatcaatgca tagtctggga
    12241 aaaattgttc aaccatactt tgtgccaaaa taacaacgat atatcctaaa gaagaaagga
    12301 gtaaaatcgt accgccaatc acaataaatt ggcccgtgat ggccaaaaga cgcgatttgg
    12361 tcaatgacca gctttcccga atggctgctc gaaaagaacg atctcgtaga atcatttccg
    12421 gtaaagcaaa aatcagtcga atcccaatat agccaaggaa aatataaacg agtaaaaagg
    12481 aactgacgat gatccaacga ttagcaaaaa taaaatccat aatgaaagcg gggattttta
    12541 tttttgacag tagatcagaa ttaaaactta atccgctgat cggtagaatc aataaaaaat
    12601 aagcaaggaa aaacaaaaaa gtaatgggtc tcactttctt cagctgaagt atcgtcaagt
    12661 gtaagagttg cttcaaagag attggttctt tctttttaat aaaaaaaaca ctcatcaaaa
    12721 gaaaagtaaa ttcgaaataa actaacagta aaatcgtcat caaaactacg attaacgaga
    12781 gtagaacccc aggatgttga gaaaaaattg aaggaatatt gtcataagac aaatagtcaa
    12841 ttgcccctcg gtgtaaaata aaacgggtcg tactgctcaa taagggtaaa caaataaata
    12901 aaataaagcc atgcatcagc aagacatcac ggaaataagc ttgtgttcct tttaaaaagt
    12961 cccaagcatt acctaagcta cgtttcaaat aattcatcct atcacctgct cttcacattg
    13021 tagcgcaaat ctaatgaaaa aggaaagggt gcagtgtgtt ttgcagaccc tttcccagat
    13081 ttaa
//
LOCUS       DBBGSZ010000059        12877 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.062, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000059 DBBGSZ010000000
VERSION     DBBGSZ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12877
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.062"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(162..2159)
                     /gene="tkt"
                     /locus_tag="ACIZE5_002496"
     CDS             complement(162..2159)
                     /gene="tkt"
                     /locus_tag="ACIZE5_002496"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGC6109600.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2261..2512)
                     /locus_tag="ACIZE5_002497"
     CDS             complement(2261..2512)
                     /locus_tag="ACIZE5_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HGC6109601.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2659..3282
                     /gene="lexA"
                     /locus_tag="ACIZE5_002498"
     CDS             2659..3282
                     /gene="lexA"
                     /locus_tag="ACIZE5_002498"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HGC6109602.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3462..3680
                     /locus_tag="ACIZE5_002499"
     CDS             3462..3680
                     /locus_tag="ACIZE5_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109603.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3969..4481)
                     /locus_tag="ACIZE5_002500"
     CDS             complement(3969..4481)
                     /locus_tag="ACIZE5_002500"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HGC6109604.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="ACIZE5_002501"
     CDS             complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="ACIZE5_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HGC6109605.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6934..7377)
                     /locus_tag="ACIZE5_002502"
     CDS             complement(6934..7377)
                     /locus_tag="ACIZE5_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA
                     domain-containing protein"
                     /protein_id="HGC6109606.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7378..8166)
                     /locus_tag="ACIZE5_002503"
     CDS             complement(7378..8166)
                     /locus_tag="ACIZE5_002503"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGC6109607.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8163..9104)
                     /gene="rnz"
                     /locus_tag="ACIZE5_002504"
     CDS             complement(8163..9104)
                     /gene="rnz"
                     /locus_tag="ACIZE5_002504"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HGC6109608.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9281..9868)
                     /locus_tag="ACIZE5_002505"
     CDS             complement(9281..9868)
                     /locus_tag="ACIZE5_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HGC6109609.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10089..11402)
                     /gene="obgE"
                     /locus_tag="ACIZE5_002506"
     CDS             complement(10089..11402)
                     /gene="obgE"
                     /locus_tag="ACIZE5_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HGC6109610.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11690..12700
                     /gene="gap"
                     /locus_tag="ACIZE5_002507"
     CDS             11690..12700
                     /gene="gap"
                     /locus_tag="ACIZE5_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGC6109611.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
BASE COUNT         3557 a         2880 c         2295 g         4145 t
ORIGIN      
        1 ctcaagaaac acaaactaat ccgaagaatt ctttgttttg tcatttaaat gtaacatagc
       61 cgaaaacgaa aagtaatatt gatttattct tctaacacat aaagaacagc tgtctccaac
      121 ttgcagacag ctgttcttat cagtcaaaca attgcttgga tctatgatag ttgattgtac
      181 gtattcacga cattttctac tgtaaatcca aattcttcta aaattttagt gccaggggca
      241 gatgcaccga aatgatcgat tgtaatcgtt gcgccctctg ttcctacgta gcgttcccat
      301 ccaaatgatg cagcagcttc gatagccaca cgtttcttca ctgatttagg aagtacactt
      361 tctttatatt cagaagattg tttttcaaag aggtcaaagc ttggcataga aacaacagaa
      421 acatctttgc ctttttcagc caattctttt tgagctttca cagccaaatc aacttcagaa
      481 cctgttgcaa tcaaaatacc ttctggtgtt tctccttgtg atggagaaag aacatacgcg
      541 ccttttttca ccatttcatc tgctacttct tttgtagaag gcaatactgg aaggttttga
      601 cgactcaata caaggatagt aggcgcatct gttgtctcca tcgctacttt ccaagcagca
      661 cgtgtttcat ttccgtctgc cggacgaatc acttgaacac caggcatgca gcgaacagat
      721 gctagttgtt caatcggttc gtgcgttggt ccgtcttctc cgacagcaac cgagtcatgt
      781 gttaagacgt aaacaacagg agtatgttgg attgctgcta aacgaactgc tggtcttaga
      841 taatcgacaa agacaaagaa tgttccaccg tagatacgag ttccgccatg aagttggata
      901 ccattcatag ccgaagccat tgcaaattcg cggacaccga accagatgtt gcgtccttca
      961 taatgttcag gagtgaaatc tttatctgca gccaccattg tattattgga acctgacaag
     1021 tccgctgaac caccccagaa gcttggtata gctttcgata attcttggat gacttcttta
     1081 cttgaaacac ggcttgcttg actgcttcca acttcataag ttggcaattc tgcatcccag
     1141 ttttctggta gtttgccatc aaaagcatct tcaaattgtt gtgctaattc aggataagct
     1201 tttttataat tggcaaacat ttcattccat gcatcttcag ctttttgtcc ttcttctatc
     1261 atcgtttgat ggaagcgggc agctacttct tctggaacag tgaaatctgg atactcccaa
     1321 ccataaactt ctttagccat cttgatgcca tcttcaccaa gaggagcacc atgaacagca
     1381 gatgttcctt ctttaggagc accatagccg atgactgttt ttacttcgat caatgttggt
     1441 ttgtctgttt cagcttttgc ttcttcaatc gctttagaga ttgcttctag gtcatttccg
     1501 tctttcacta agatatgttg ccagccatat gcttcatagc gagcaccaac gttttctgtg
     1561 aaagcttttg aagttggacc gtctagtgaa atatcgtttg aatcgtataa aacgatcaat
     1621 ttccctagtt tcatatgacc tgccatcgaa cttgcttctt gagatacccc ttccatcaag
     1681 tctccgtcac cgcatattgc atacgtatag tgatccatca cattaaagtt ttctttgtta
     1741 tacgttgctg caaggtgcgc ttctgccatt gccataccga cagccattgc aatcccttgt
     1801 cctaatggcc ctgtagtggc ttctacacca tctgtatgat gtacttcagg atgtcctggt
     1861 gttttagaat cccattgacg gaattgtttc aaatcatcga ttgtcacttg atagccagct
     1921 aaatgaagca agctatacaa cattgctgac ccatgtcctg ccgaaagaac gaaacggtcg
     1981 cggtcagccc agttttttga tgtcgttgga tttactttca ggtgttttgt ccataacgca
     2041 tatgccatag gtgctgcgcc catcggcaat ccaggatgtc ctgagtttgc tttttggact
     2101 gcttcaatac ttaatgtacg aattgtgtta acgccaagtt ggtcaatttt gtcaaacaaa
     2161 ataacccctc ctattaattt aggttttttt tacctttatt tcttacactt tcattctata
     2221 agatgtcaca cgaaaaagca atctttttca gtatttttta ctaaaagttg tcatttcggt
     2281 tgtgtaagcc ttttttcttt tggatttctt ttaatttttc cggggtcacg tcattgccct
     2341 caggatcgac gactttcatt ccttcgatat gatgacgcat accggaacga aaagcttcca
     2401 aatactcttt gcgcaagttg atttgttctt gttcttcggc ttttgagaga ccattttcct
     2461 tctttttacg tgcaagttca ttgatccgct ctattttttc aggtgacagc atgctcagcc
     2521 ctccttttac tctccttcat attatataaa aactgaaaaa aaaacaacta gataaactaa
     2581 ataaaatacg aacattcgtt tgatttagcg ctttttatat ggtactattt atttatcaag
     2641 tgaaagaagg tgtaccttgt ggcccgacaa actgaatcaa gacaaatcga agtcttacga
     2701 tatatccatg aacaagtaac ccaaaaagga tacccgccga ctgtccgtga aatcggggaa
     2761 gctgttcagc tttcttctac ttctactgtt cacggtcatc ttgcacggct tgaaaaaaaa
     2821 gggtttatcc aaagagatcc gacgaaacct cgtgcaatcg agttgacaaa acaaggttta
     2881 gaaaagattg ggattcgtcc aacaactatt ccagtacttg gcgtcgtaac agctggagaa
     2941 cccattttag cagtagagga tgcttcagac ttctttccaa tccctcctaa tctttcttcc
     3001 gaagaaggca gtctctttat gctgacaatt cgtggagata gtatgatcaa tgctgggata
     3061 ttggatggtg acaacgtgat cgttcggaag caagaaactg ctcaaaatgg cgatattgtc
     3121 attgcaatga ctgccgagga cgaagcgact tgcaaacgat tctataaaga aaaaaacttt
     3181 ttccgtctgc agcctgaaaa cgacttgctc gaaccaatca tcttagatca agtatctata
     3241 ttaggacgag tagtaggact ttatcgtagt catatctatt aattgctact aattaaaaga
     3301 aaacttttta aaaagagttt gagacgttgg tctcaaactc ttttttcgcc cgggttcttc
     3361 ttctttcaaa tttttatcac ttccctcttt acaaaccgaa caaatattcg tatactaaat
     3421 atacgaacaa ttgttcgcat aaattaaaga ggtgagaatt catgaaatca atgagacgtc
     3481 ttggcttagt attaactgtt ttgtttttag gtattattat tggtaatttc ggcatacgtc
     3541 cagctttact tgtgtttgtt ccgttattta ctttgtggtt catgttgtgg gatgaaaaga
     3601 agtaccgtca atctgagcgg cgcagaattc atgaagatca tttctatcat gagccctact
     3661 acagatccag gcaatcataa taaggattga ctgctaatta ttcaaaagac aagaagttaa
     3721 acttttacgg gggtgtgaca aaaatcggtc acatcctttt tttcgaataa acggtgttct
     3781 aaagccagtt tttcggtatt aagtcaaatt gcggaaaaag tgatttttta aacttctact
     3841 ggtctttgct tgtttccatt tataaaaaaa tagcgaccct caaaagtcag atagagaatc
     3901 tgacttttga gggtcgcttt aaaatcgctt ctttaagaat aacatcaaga atagcttctt
     3961 ttttctgctt aatattccat taatgtaatg atgtcatatc ctttgatttt gtcgcgtcca
     4021 tggagatcca tcaattcgat caaaaatgcg cagcctacga ctacaccgcc taattgttcg
     4081 atcagttcga tcgtcgcttt gattgttcct ccagtagcta gcaaatcgtc acaaatcagc
     4141 acacgttgac ctggtttaat ggcatcctta tgcaatgtca atgtatctgt tccatattct
     4201 aatccataag tcacttcgat ggtttctcga ggtaacttcc cttttttgcg gactggggca
     4261 aaaccgactc ctaactcata agcaacagga catcctacga tgaatccacg ggcttctggc
     4321 ccaactacca tatcaattcg tttttctttt gcataattta cgatttgttt agtagcttcc
     4381 cgataagcgt caccatctgc catcagtggg gaaatatctc gaaacacaat tccttttgac
     4441 ggatagtcgg gaatactggc aatataatct tttaaatcca ctctttgttt cctcctaggt
     4501 tgttaaccat ttctttatgg taggaatatc gctcaaaagc aaaaattcct caactttgat
     4561 tttattgagc cgtcgctggt ataatctgct ctcagtcaaa ggatgacttt ctgggctagc
     4621 gactttttgt aaaacaccgt tctctattgt aacaaatttc aattcaaaaa acacctgtat
     4681 cataaaaatt aataattttt cagggatacg caaatattga gctattgctt ttattttatg
     4741 acgtatatca attcgttctt gagaatggat caatttaaac aattttgcgt actgttctct
     4801 tgtgcctacc ccattcaaat aggcctcatc aggtgaaatc cccatcagat aaacacgatt
     4861 gaatgaataa gaccgaaaaa cttctttcag atccgctaaa tcatctggac aatccataac
     4921 aactagagag tttggttttc ttttttcaat tattgccttt acagaatcta gtccttcgaa
     4981 aacaatcgca gcttcctgga taatctcagg cacgaatttc aacgtcgaag aatcaaatgc
     5041 taaataaagg ctaccttccg acgttcggct ctgttcacgg aaacgttttg cccgccaatc
     5101 aaatacttgc agaccaccca cagaaaaatc agataccatc agctgcggtt tcttacgccc
     5161 gttccattca ttgatcgaaa gctttcctac cacatctacc tgattattca gcagttcttc
     5221 ttcttgagta ccaaaaccaa aagcgaccgc atcaagctga ctcgatgcat cggaaaggac
     5281 aaatttcaga tgctgttggt ttgctccgat tcttttgata ttttctgctt ggacttgtcg
     5341 aaataaaaac tgaggcaaag gattatccgt accaaatggc gccaatagtt tcagctcatc
     5401 aattcgctct actgttactt catttggcag caatacttca tcaattctca actcaggccc
     5461 tctcatcaag tcaatttgat gatcgactat atattggttc atcttctcct gtagtatagt
     5521 gacattttca cttggcatcg ttaaaccgac tgctgcatga tgtcctccga agtaagtaaa
     5581 taaatctcgc atctggtcaa gcatttcaaa aagattcaag gcttcaatac tacgtccaga
     5641 tcctttagct gatccatctt cttttaaagt aaggacaagc gttggtttac ccgtttcatt
     5701 cattattttc ccagcaacaa tgcccaaaac gccttcatgc catcctcggt ttaccaatag
     5761 atggatatga ttctccttat tgaccatcgc taatgcttct tgtgttatct gctctacgat
     5821 tgcttttctt tcttcattga tctcattcaa tttttttgct tgaacggatg cttcctcttc
     5881 atcaaacgtc gcaagtaacg agacggcagg acgtggatcg cccatccgac cgattgcatt
     5941 tagtctggga gcaatcgaaa aaccgatcgt tgtttcgtct gcgtccctca tttttacgcc
     6001 gctttcttca aatagcgcct gaagtcctat ccgttctgaa tgatgaatgg catcgattcc
     6061 taatgaaaca aggattcgat tctcatcagt caatgaaact aaatcggcga tcgttcctat
     6121 cgctactaaa tccaaaaatt ctgcaggcgg ttcttccaat aatgcagaag ctactttgaa
     6181 tgctactccg actcctgcca aatctggaaa tggatagtgc cccgctggat gacgagggtg
     6241 aacaatcgca taagcgtctg gtaaattctc aggtagttcg tgatgatctg taatgatcac
     6301 gtctacacca gcttgctgag cgtatgctac cgcatcattt cctgctaccc cgttatcaac
     6361 agtgatgatc aactggattc cttcttcgat cttttcttgg tataccgatt ggtttggtcc
     6421 atacccatgc tcaaatcgat ttggcaggaa tacttctact tctgcaccaa gtaattccag
     6481 tgtttctttc attaccgttg cactggtgat cccatctgcg tcataatcac cgtaaacgag
     6541 gattttttct ccactgatta cagcttcttg gattcggctg attgctttat ccatatcgtg
     6601 tatcagatac ggatcatgta attcttgttc ctttggatgt aaaaatcggt tgatatcctt
     6661 ttcctcatgg taacctcttt gccacagtaa cttaccgaca aatggagata atttcagttc
     6721 acggatcatt tggagaaagg attcagaagg ctctgtctcg cttaacttcc aatcaaaatt
     6781 tgcttgtctc actttctcac tcctaactta gttattatag caaaggaaat cagcaaaaaa
     6841 aagcagaaag aaagaataaa aacagatcag atccgctaga cagatgttca gcaggacctg
     6901 atcttttgta cgaccattta tgaaatatcc ctattagtca aaataattga agctttgttt
     6961 gggcgattga gttttttgtt cttccggcgc tttcaattga ctgatttgtg cggttttcgc
     7021 ttgtaactcc gcctgataag cagcttccaa ctccgcacgt tcgtttctaa actcgcgttg
     7081 ctgttcttct tttgcttctt caattttctt ttgaagttct gtttgatatt ctgacatttc
     7141 ctgagtcagc tgtttgattt gctttttttg ctgccatagt gttgccgaag cagtcaaaaa
     7201 tacaatcagt gcaccaatca gcgcagaacc gatgatcact aagatcaatg gcgcagaaaa
     7261 ggaagtgaag ccaaaactta caggaacatt tttattgttc aatacagcaa aaagaacaat
     7321 aatcaaaact aaaacaaatc caagaatcac attgctttgc tttttcaatt ccttcaccta
     7381 ctttttgtta aaaattccgc tggctaaata atcaccaatc gttggaaaca gcgtataaaa
     7441 ttttgatgca acttctaaaa taaacggttg attgatttcc cgttttggat gtctcatatt
     7501 gcggacgatc atttttgcca acttggcagg ttctaaaacg atttgtccga ctttttccaa
     7561 atagcttccg cttggatcag ccttatcgaa gaaatttgtc tcgattggac ctggattcac
     7621 tgtcgtaaca gctacgccaa gtggtttcaa ttctaatcgc aaagcgttgg agaagccaag
     7681 gactgcaaat ttcgtggcag aataaaccgt tgattttgca gttgccattt ttccagccat
     7741 agaggcgata ttaatgatat gaccttgtct tctttctgcc atatcgatcg caaatttttg
     7801 tgtcaaaacc atcattccta agatgttgac ttcaaacata tcgtatgctt ttccaaggtc
     7861 gaatgtaagg aagtcttcga aaatcccaaa acccgcattg tttaccagaa tatcgacgcg
     7921 cccgacttct tccatcacct tttcatataa ttcgtccacg ctttcaggat tgctgacgtc
     7981 taccttgaaa gcataagcct ctttgccgct caagcgtctg cactcgtctc tgacaccttc
     8041 tacaaatgcc attcttcgtg cgcaacttat aacgattgct ccttgctttg ctgcttcata
     8101 acagatttgt gcgcccagac cgcctgaact acctgttact aaaacaactt tatcttctaa
     8161 attcatgcct cttcctcctc gcgaaatgga atctcaatgc tatcaaaatc tttcataatc
     8221 gtcgtgtttt caaacacttc ttgtgcttct ttttcaagct ctaaagctgc ttttcctaaa
     8281 tatctcgcac tgatatgagt aagtagcagc cgttttgcct gcgcttcttt tgcaacttca
     8341 gcagcttgat gagtcgtgga atggaaatag ttgtgcgcca ttcttgcttc atctttatta
     8401 aatgtgcttt catgtaccag aatatcgcta ttttccgcaa gcacaacgga attatgtgtt
     8461 tttctcgtat cgcctaaaat agtcacgatt cgtccttttt tatctggacc tacgaaatct
     8521 tttccattga tcgtccgccc atcttctagt tggatcgttt caccttgctt cagtttgccg
     8581 tacagtggtc cagctggaat acctaattct tttagacgat ccacctgcaa ttctccttta
     8641 tgatcatgtt caaccacacg ataaccaaaa ctgtcgatcc catgatttag tttttttgta
     8701 taaacagaaa attgctgatc agtaaaaatc ggggctgttt catttagctc aatgaatttc
     8761 agcggataac ttaaacgcgt ttgcgaaata cctaaagaga cttttatgta ttcctctatc
     8821 ccttttggcc cgtaaatctc taatggcgta tccccacctt gaaatgaccg gctgctgatg
     8881 agcccgggaa gtccaaaaat atgatcgccg tgtaaatgtg taatgaaaat tttaccgatt
     8941 tttctcggac gaatagtcgt tcgcaaaatc tgcatttgcg tgccttcgcc acagtcgaac
     9001 aaccaaactt cattgcgctc gtctaaaagt ttcaatgcta tacttgtcac atttctatgt
     9061 tttgcaggaa cacctgcacc tgttcctaaa aattgtaatt ccataatcta cctgactttc
     9121 tttaagttcc tctttaattt tagggtaaaa agaagggata atcaaccgta agtcgagaat
     9181 gggttcaaat taaaaataac gttctaaagc gatagcgttt tctttgaaaa ttactataaa
     9241 aacagcagcg aacccgtttg agatcctctg ctgtttttta ttaatttgaa gatccagaac
     9301 tttcattgtc gttggaagtt tgcggatgtt tgtccttcca agtcttttgt gcagcttctt
     9361 tcgcatgatt ttcagcttct ttcgcatcat gcacatcttt ttcgacatct tcataatcca
     9421 agcgagtaat ttctccgcct aattccatca ttaccaattg attcagtggg cgattgtcct
     9481 cttcatcagc aatcaagatc agtcctgtag ctccttcacc gattttattt cctacaaagt
     9541 cgaacacggt ctgggcatct tttatttctt tggcatcttg tgtcgcaccg atcattcctc
     9601 cggcaaacca tcctaataaa atccctagcg gaccacctaa tacaccaacc aacattccga
     9661 ttaatccacc cgtagaagat ttgttattac cggtaaagtc gataaaatct tctattttga
     9721 attgatgtgt cccattagga tcatggctga caactgccat ctgttctcct ttaatcgaac
     9781 gaacagcatg taactttttg atttctgaaa atgcctgata tgcctggctt tctacttgaa
     9841 aatttaaaat gattactcgt ttgctcatta aaaacgcccc tttcatacct tcttgttatt
     9901 tattttacct ttaattgaaa aataagaaaa gaaaagcact ctttttttcc aataaaatag
     9961 ggctgtgaca aaagtcgtat cacagctcct ttttccgaat aaacggcgtt cttgaagctg
    10021 atcacttctg tcacaacctc ccttaaatct gaatctatat tttttggtat ttgtttttat
    10081 ttgcttgcct attcgacaaa ttcaaattca aactcaccga tacgtacaag gtcgccatct
    10141 ttcgcaccgc gtgcccgaag agcttcatcc acacccatac cacgtaattg acgagcaaaa
    10201 cgcatcactg tttcatcatg atcgaaattc gtcatttgga ataatttttc gatcttctca
    10261 ccagataaga tccacgttgc atctgaatca cgatcgattt ggaactcagg accttctgga
    10321 ttgaatccat agtgtacagt ttcttcttcc agttcttctt cgtacaatgg gaattctggc
    10381 gttacttcta acaaatctgc tgtagcattc aataacgcgt ccaatccttg tcgagtcact
    10441 ccagaaattg gaaatactgg gatgtcatca gcaaattcat cttctttttc cttgttcagc
    10501 tgttctttga atttcactag attttccggt gcatccggca tatccatttt gtttgccacg
    10561 atgatttgcg gacgctctag caagcgtaag ttataagtag ataattcttt gttgatggca
    10621 agatagtctt cataaggatc tcgtccttcc atcccactca tatcgatcac atgtaaaatt
    10681 actcgtgttc tttcgatatg acgaaggaat tgtgtaccca gcccaacacc ttgcgaagct
    10741 ccttcaatca agcctggcaa gtctgctgcg gcaaaacttc tgccatcact tgtagtaacc
    10801 attcctagat taggtacgag cgtcgtgaaa tgataagcgc cgatttttgg acgagcagat
    10861 gaaataacgg atagtaaagt cgatttcccg acagatggaa aacctacaag tccaacgtct
    10921 gccaatactt tcaattctag ttcgattttt cgctcttgtc ctggttcacc gttttcagca
    10981 atttccggtg caggattccg aggagaggca aaacggatat tccctcgtcc accgcgtcca
    11041 ccttttgcca caactagtgt ttgaccattt tcaattaaat ctcctaaaag agcaccagtc
    11101 tccgcatctc ggacagtggt tccttgtggt actttaacat aggtatcttc tgaaccacga
    11161 ccgtgcatcc ctttactcat cccattttca cctggctgcg ctttgaaatg gcgattgaac
    11221 cgaaaatcca tcaatgtacg taacccttca tcgacgatca agatgacatc gccgccacga
    11281 ccaccgtctc cgccagccgg tccgccgtca ggaacgtatt tttcgcgacg aaatgcaacc
    11341 attccgtctc cgcccttgcc agctttcaca tcgatcgtta cttgatctaa aaacatggac
    11401 ataattaagt cctcctatta ttcatttatt tatttgactg cctgaatttc cacaataaac
    11461 aaaagtctta cttattttat cggtgaaatc tgattttgtc tatcatttca gcaaaaagat
    11521 tgtttacctt cttctttttt tatcatttgg taaggtttcc aacctttttt ctgctaccaa
    11581 gtataatttt ttgacaaaat attctttgcg tagcagaata acagtgtatt aattgtatta
    11641 attgaggatg ccgtttcaca gcacccctaa taaaggagga acttttgata tgacagtaaa
    11701 agtaggtatt aacggatttg ggcgtattgg ccgtctggct ttccgccgca tcaaagaagt
    11761 ctcagatgat attgaagtag tagcaatcaa cgacttaaca agtccaacta tgttagcaca
    11821 attattgcaa tttgactcta ctcatggtac ttatcctggc acagttactg caacagaaga
    11881 ctcaatcgta gtggatggcg aagcaactcg tgtttatgca gaacccgacg caagcaaaat
    11941 cccttgggca aaagaaaacg gtgtagatat cgtactagaa tgtactggtt tttatacatc
    12001 tgaagaaaaa gcaaaagcgc atttagatgc tggtgtcaaa cgagtagtta tttctgcccc
    12061 agctggtgct atgaaaacca tcgtctataa cgtcaatgat gatacattag atgaaaacga
    12121 caaaatcatc tcagcaggtt catgtacaac aaactgttta gcacctatgg cttatttctt
    12181 aaataatgaa tttgggatcg aagttggtac aatgacaaca gttcatgcct acacttccac
    12241 acaaatgctc ttagatggac ctgtaaaagg cggtaatttg cgtgctgctc gttcagctgc
    12301 tgacaatact atcccacatt ctactggtgc tgcgaaagca atcggcttag ttatccctga
    12361 gctacaagga aaattacaag gacacgcaca acgtgttcca gtcgttgatg gttcattaac
    12421 tgaattggtt tcagtattga aaacaaaagt aactgctgat caagtaaacg aagcaatcaa
    12481 aaaacacaca gttgacaatc cttcattcgg gtatgatgac cgtcaaatcg tttctagcga
    12541 tgtcattgga acaactcaag gttcgatctt tgacccaacg caaacagaag taacaactgc
    12601 tggtgatttc caacttgtta aaactgttgc atggtatgac aatgagtatg gatttacttg
    12661 ccaaatgatt cgcttactag aaaaattcgc taacttgtaa tttgatagat caatcgataa
    12721 aagaagcctt tgactggatc cagtcaaagg cttctttctt ttcaggctct tcgtcaaatc
    12781 gtgttggtga agacaaattt gaataaaact tagaccgata tgcggcgcgt tctgtgcgcc
    12841 gcatattttt ttagttttca aagatcagac cttgttg
//
LOCUS       DBBGSZ010000060        12744 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.063, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000060 DBBGSZ010000000
VERSION     DBBGSZ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12744
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.063"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            683..1357
                     /locus_tag="ACIZE5_002508"
     CDS             683..1357
                     /locus_tag="ACIZE5_002508"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGC6109612.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            1354..1695
                     /locus_tag="ACIZE5_002509"
     CDS             1354..1695
                     /locus_tag="ACIZE5_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109613.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            1725..2084
                     /locus_tag="ACIZE5_002510"
     CDS             1725..2084
                     /locus_tag="ACIZE5_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HGC6109614.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            2608..4689
                     /locus_tag="ACIZE5_002511"
     CDS             2608..4689
                     /locus_tag="ACIZE5_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGC6109615.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            5000..6466
                     /locus_tag="ACIZE5_002512"
     CDS             5000..6466
                     /locus_tag="ACIZE5_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGC6109616.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            7081..7620
                     /locus_tag="ACIZE5_002513"
     CDS             7081..7620
                     /locus_tag="ACIZE5_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HGC6109617.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            7694..8134
                     /locus_tag="ACIZE5_002514"
     CDS             7694..8134
                     /locus_tag="ACIZE5_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HGC6109618.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            8147..8356
                     /gene="copZ"
                     /locus_tag="ACIZE5_002515"
     CDS             8147..8356
                     /gene="copZ"
                     /locus_tag="ACIZE5_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HGC6109619.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            8356..10542
                     /locus_tag="ACIZE5_002516"
     CDS             8356..10542
                     /locus_tag="ACIZE5_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGC6109620.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            10562..12733
                     /gene="copB"
                     /locus_tag="ACIZE5_002517"
     CDS             10562..12733
                     /gene="copB"
                     /locus_tag="ACIZE5_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HGC6109621.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
BASE COUNT         4286 a         2150 c         2784 g         3524 t
ORIGIN      
        1 aaaaagaact gcgaactctc gcagttcttt ttttaaaata cgggataaag gaagtttcca
       61 gcagacaaga gaagaaagca aaagaaattg ctatttgatt cacaaggttc tataacgaaa
      121 tcgcaatcaa tcaaacattt acaaagaagg taattcaaat ggaaatctga tttgatgatg
      181 cttctgctgt tgaaataaag cagcatctag cacctgaaaa caaactaata gtaacattcg
      241 aagatggagt aggtccgtat tttcagcatg caataatcca tatgtaagtt caattcaccc
      301 ttgaaatcat cggaccagat aaagttatga ccaatctatc ccaagcaatc tagaagagat
      361 attagtaaag ggacatttac tagaagtctt agatgagcct ataaatatat gttctgatgg
      421 cgtcatcagt ggtctgattg acggaagctt aggtgtgatc gatctctctg gaccaaacaa
      481 cgaaggaatc aaggggaatc cggcacgtta agaaaaaaat agcataaaaa actagacact
      541 tgatgagcgt tcattcaatt gtttgaaggg actaggctgg tgtcattttt tatacatata
      601 ttttctcttt cgtcttgata gggcttatgg gataatataa ggaagaaaat catcgtttta
      661 ttcaaaaagg agtttttgac aaatgaaaaa acgtatatta tttatcggtg atagcattac
      721 agacgcagga agagaccgag cagaagcaac tgatctaggt aaaggttatc cacttttgat
      781 tgccggaaaa ctaatctccc aatatccaac gatggaattt gaatgcatga accgtgggat
      841 aggaggagac aaaattgcag atctgcaagt acgctggcaa gaagattgtt tagctttaca
      901 acctgactat gtatcgattt tgatcggaat caatgatacc tggcataata ctagcgatca
      961 ggctatattc ggaactgaga aatctgctca gcaatttgaa tccgtttatc gaaaattact
     1021 aaatgaactt caaacagtgg gaatctgcaa catcatcttg atggagccgt ttgtacttcc
     1081 tataaccgac gaccgtcatg gctggcgtaa agacttagac cctaaaatcc aaattgttcg
     1141 taaacttgct aaggaatatg gcgcattgct ggttccttta gatggtatat tcaatgcttt
     1201 agggattgtt tatggttttt cgaaatatac aagagaagat ggggtccacc caacgattgg
     1261 cggacatgag atcattgcac aaagctggat agatgcaatt gccgcagtcg atttttttag
     1321 tggagataaa aatgagcgaa agaaaagtga gaaatgatgg aaatacggtg ggcagtaaaa
     1381 gaagatctac ctcaaatcaa tcagctgatt actgatcatc cagaatcatt cgtaaaagca
     1441 aaaacggcag ctgacctaaa tgataagaat aaactattgc tcgttgctgt aacaaaagaa
     1501 aaacggatta tcggatttgc gcaagcggac gtgcaacagt cagaagaacg attggatcag
     1561 cgaccatcag gaaaactaat ccaacacaca ttagtaacaa aagaaaatac ggaagaaatc
     1621 caaaaaaaat ttgcagaata tttgatactg gaagctaaaa aaagaagaat aaaatcattt
     1681 tttgcccagt tttaatcaaa aacagtaata gaaggagaaa tacaatgagt tgtttaggaa
     1741 atgtcatctg gtttatattc ggcggactaa tcggtggtct tagctggtta gcagcgggga
     1801 tactttggtg tatcacgatc ataggtatcc caatcggtat gcaatgtttt aagatcgcct
     1861 ccctttcttt tgcgcctttt ggcaaagaag taatttatca ccagtctggc atgtcattga
     1921 ttgttaatat catctggctg atcgtttcag gcctaccaat tgctctcgca catgtcgtca
     1981 gcggcatcct tctatgtatc acgatcatag ggataccttt tgccaagcaa tctttcaaac
     2041 ttgctcgatt ggcgttgatg ccattcggtg cagaaattgt ataaaagaga ataataaagg
     2101 ttagataaag catagagtca ggtgggatac atgtatttca cctgactcta tgcgttctcc
     2161 tgtataagtt cttccatgtg acttttacgt cttttattta tatggggtta ctgtttatgg
     2221 aaagttgaaa taattttcat taaagaactc tttctatatt tttgaaagcg tagtggagct
     2281 tcgaatatct gggaaggaca ttttgcaggg attgaaaaaa gatattgtcc tatcgaaaaa
     2341 ttaatgaatt tagacaaatt gccagcaaca ggcttcaaac ttagttgcta tcctgtcaag
     2401 atcaagaagg caagtgcggg ttggataaga gcagtggcaa tgatcgaaaa gaaaaagaaa
     2461 gaataagcca aaacatctgt atggaagaaa ttttccgatg cagatgtttt tcattttttc
     2521 tttcggatac cttgacatat gaataaccgt tcatttataa ttagttatga agagatattc
     2581 atatgttgag gcgaggaggt cattaaaatg aaaagttaca gattagaagg tttagattgt
     2641 gcgaactgtg caatgaaaat cgaaaaagga gttcagaaga tcaatggagt caaggaagca
     2701 acggtaaact tcacttctgg aaaactaacg attgacgcag aggaagatca tttggctacg
     2761 attgaacaag aaataaaaaa agtagtgaag gaattagaac cagatgtcaa agtaacagaa
     2821 atagataagg aaaaagtatc tgaacatgga aatgaaaaag agagaaatac gctgttccgg
     2881 attttatttt cccttgcagg tatcgcttta ttgctattat ttgattttaa tgaaccaatt
     2941 cgcttgatag ggtatttatt gatttatctg ctgataggat atgatgtagt gaagaaggca
     3001 gtgatgaata tcgtcaaagg aaaaatcttt gatgagaatt ttcttatgtc tgttgctacg
     3061 attggcgcta tgttgatcgg tgaatatcca gaagccgtag cagtgatgct attttatcaa
     3121 atcggcgagt atttccaagg attggcagtc agtcattcaa gaaaatcgat tcgcgaattg
     3181 atggcgatcc gtccagaaac agctcacgtg cagacgacgg aaggattgat gaccgtgaac
     3241 cctgaagacg tgcagatcgg tcagtttgta cttgtgaagc ctggtgaacg tgtaccgtta
     3301 gatggaacga tcatcgaagg agaatcatta gtcgatacgt cagcacttac aggagaatca
     3361 gtccctaaat ctgtatatgt tggtgaaaca gtattaagtg gatttatcaa taaaaataaa
     3421 ccatttttag ttcaagtaga aaaatcttat gaaaattcta ctatcagcaa attattagaa
     3481 ttagtagaaa atgccagcag taaaaaagca ccagctgaaa atttcattac taaattcgcg
     3541 cgctattaca caccagtcgt tgtaggattg gccgttttat tagctgtttt acctccactt
     3601 gttgtttctg gagcggcgtt ttctgaatgg atctatcgag cattgacatt tttagtgatc
     3661 tcatgtccat gtgcattagt gatctccgta ccccttagtt tctttggcgg tatcggagga
     3721 gcaagtaaaa tcggtgtatt agtaaaaggt tcaaattact tggagttgct tgcacaaact
     3781 gagacagtgg tattcgataa aaccggcaca ttaacgaaag gtgacttttc gatccagacg
     3841 atcgatacaa aaatcgatcc aaagatattc atgcaatatg ttgcgagtgc agaacagttt
     3901 tctacacatc cgattgctca atctgtttta gaaggctacg caggtccgct tttaccaaca
     3961 gctaatatcc aagaatttgc aggtgaaggg atcttagctg aagttgatgg caaacaagta
     4021 ttagcaggta atcacaaatt gatggaaaga tttgaaatct cttttccttc aagtcaagaa
     4081 atcggtacat tgctttatct agcgatcgat caaagttaca gtggttatct tgttattgca
     4141 gataccttga aagaagatgc cgtagacgca ttggttcaat taaaaaaggc tggtgtgaag
     4201 aacacagtca tgttgacggg cgattcgaaa aaaattgctg atcatatcgg gaagcaagta
     4261 ggcgtggaca agatatatag cgaattgctt ccagaagata aagtgcagcg gttagaggaa
     4321 atcttacaaa gaaacaataa aaagaccgca tttgtcggag atggaatcaa cgatgcaccg
     4381 gtgctagcaa gagcagatgt aggaatcgca atgggtggat tgggaagcga tgctgcaatt
     4441 gaagcagcag atgtagtcat catgaatgat caaccatcga agattgcaga agcaatccat
     4501 ttagcaaaga aaacattgaa aatcgtcaaa cagaacattg tctttgctat tgggataaaa
     4561 attttggtac ttgccttagg tgcttttggt tttgcatcaa tgggagatgc agtatttgca
     4621 gatgttgggg tgacagtatt agctgttttg aatgccatgc gaagcttgca tgtaaaaaat
     4681 aaacgttgat caatgaagag gacgaatgaa cgtcctcttt tttttatatc cttttcttaa
     4741 tgaaaaatgt aaagaaaata gataggatta taaaataact aatgttttta attttgcaga
     4801 aaattcaaaa tagcttgaaa ttcaataagg taaatgaaat aaaagaaaat aacttatttt
     4861 tttgatggaa aaaatatgaa aaaacgatgt gtattaaata aaagaataca cacataaaat
     4921 aacactgtct tgtaagtttg ttaaaaattg aatatgatta catctggata acaaattttt
     4981 atcataaagg agagaacgaa tgaacaacaa acaattacgc tggtttactg ttgcgttaat
     5041 tgcatttaac atggtttggg gcatggggaa tgtagttaat aactatgctc agcaaggagt
     5101 atcagttgtc acctcttggc tattgatttt ggccatttat tttattccat acgcattgat
     5161 cgttggacaa ttagggtcag ccttcaagga tagtaaagga ggcgtcagtt catgggtcga
     5221 aaatacgaca tctaataaac gactggcata ctatgccgct tggacttact gggtcgtcca
     5281 tattccttat ttggcacaaa agcctcaagc aatcctgatt gctggcggtt gggcagtcca
     5341 aggaaatgga aatatcgtaa atacgatgtc agtacaaatg gtagcagtta tttcacttat
     5401 tatatttctt gcctttttat atttatcaac aaaaggactt tctactttga aagtgattgg
     5461 cggactggcc ggaacagcga tgttcgtcat gtcgatctta tttattcttt tagctgtaac
     5521 ggcaccgttc atcaatccaa cgatggaatt tgccacacca catatgaatc aagtgaaaac
     5581 atatattcca acatttgatt tcagttattt cacaaccgtt tcgatgctag tatttgcagt
     5641 tggaggagcg gaaaaaatat ccccttatgt caactctaca agaaatcctg caaaggaatt
     5701 tcctaaaggg atgatcttct tagcagcaat ggtagggatt tgtgctgtat taggctcagt
     5761 cgcaatgggt atgctgtttg ctagcgataa tattcctaaa gacttgatgg caaatggggc
     5821 atacagtgct tttcaaattt taggtaatta ctatggtatc ggtaactcat tgatgatcat
     5881 ttacgcattg acaaacatga ttggacaaat ctccgcatta gccttttcaa ttgatgcacc
     5941 actaaaaatc ttgttagcag atgcggatcc agaatttgta ccaaactggc tacgtaaacg
     6001 taatcgtaaa ggtacattgg tgaatggtta tcttctgaca ggtatactag taggaatcat
     6061 tattttgttg ccgatctttg gtatcaaaga tatgaatgaa ttagtaaaat ggttgacgaa
     6121 cttgaactca gttgtcatgc caatgcgtta cctatgggtg ttcttggcat atatgatgtt
     6181 gaataaagct tataagaaat tcaattctga atataaattt gttaaaaatc caaaaatcgg
     6241 ttttatcttt ggtgcttggt gctttgcctt cactgcgttt gcatgtatcc taggaatggt
     6301 gccaaaagta gattatactg ctgatcctaa agcatggtgg ttccaattat tcacgaatat
     6361 catcacacca attgtcttga tcttattagg tatgatcttg ccagcaattg ctcgtcgaga
     6421 caaaaacaaa gaaatcactg aaccagaaac agtggttcag ccttaaaata gaaatacttg
     6481 ttacaagagg ttgtgacaga agtggtcagc ttcaagaaat aagaaggaat ttacgaaaat
     6541 tgcttctcaa atttttgtga agtttcggct tgtttttcgc agaagctact tctggaacac
     6601 cgtgaatcag aggttgtgaa aaagctgtcc tgcatcaagt aataagaaca gccaaacaaa
     6661 aatagcccct catatttttc gttttgctgg gcttattacc gcagatgcaa gcttttgaac
     6721 accgtttaag aaagaggtag tgagcctgcc gtttaactcc gagtcacaag gagcaatttc
     6781 aaaaaacaac ttctcatgtt tgttgactat tgtgccttgt gaccgaggtg ttggcaggag
     6841 aacaccgttt aaggaagagg ttgtaaaatc agcgatttga cctgagtatt agaggaacaa
     6901 acgaaaaaat agctcctcat attttgccgt tttttgagtt aatgctgaag gtcagctgat
     6961 tgaacaccat ttattcgaaa caagggactt tgacacgact tttgtcacag tcccttgttt
     7021 ttttgcggcg ttataagtgg tatgatcgaa ccaaattcca aagagaagtg agggagaaga
     7081 atgaagatca tcgtgattgg acaaagtggg tcgggaaaat cgaccctcgc aaggaagatc
     7141 aaagaaatca ccgactttcc gctactgccg ctagaccttt tatggcatac aacagactac
     7201 agtattcagg caaaaaagtg gtttttgcaa gaacagcaat cgtttatggt atctaatccg
     7261 tcatggattg ttgaaggaaa ttatacttct acattagagg aaaggattaa agaagcagat
     7321 aagatcattt ggcttaaagt gccgcgttat ctcgccatct accgagtagt ttggcgttct
     7381 ctaaaaagaa agataaacaa aaaatctcgg ccagatatgc ctgaatcatt ttcagagaaa
     7441 ctaaacaggg aatacttaga atttttatct tttatctggc attttgaaga aaacaatgaa
     7501 ccgaaaatac agcagctgat ccaagtagct aatgcaagaa ataaactgat catccttaaa
     7561 acaagacgag agaaacaaga atttttaact aaattgaaaa tagagagcaa aaataattga
     7621 cagtttttgt ttacaagcgt aatctgtatt cataagctaa tgattacatt tgtaaacgaa
     7681 aggtgtgaaa taaatggaaa aagtcaaaac gccagtaaag atcagtgatt cagagtggga
     7741 gatcatgcgt gttatttgga cacttggaca gacgacagcc caagaaatca cgcagatctt
     7801 agctgattcg atggattgga aaccagcaac gatcaaaact ttgctgggac gtttggtaaa
     7861 aaaagaagtg atctggacag aacaagaagg aaaaaaattc atttatcatc cagctgtctc
     7921 ggagatggaa acagttcgca gtgcgacgga aaatcttttt tcccatatct gtgcaaaaag
     7981 gattggagag acgattgcgg atctagtaga agaagccact ttgactcaag aagatatcaa
     8041 tgagattttg aaacaactgg aacaaaagca accagtagat acgatcgaat gtaactgtat
     8101 cccaggtcaa tgtgaatgta aacaacatca ataggaggaa gaaaaaatga aacaacaatt
     8161 ttcaatcgaa ggtatgagct gcaatcattg tgcagcaaga gtagaagaaa cagtaagcgc
     8221 acttgacggc gtgcaaaaag tgaaagtaaa tttgaaaaaa gcaaacggta cggtcaagtt
     8281 tgatgaaaca aaagttcaat ccgaaaagat ttgtcaagca atcaatggat tgggttataa
     8341 agcagaggtg atttgatggc aacagcagaa accaaaatgg atacgttcgt cattacaggt
     8401 atgacttgtg caaattgttc tgctaggatc gaaaaagagc tgaacggaca acctggtgtg
     8461 gtcaatgcca cagtcaactt ggccactgaa aaagcaagtg tcaaatatga agggacgacc
     8521 actgaaaaat taatccaaag cgtagaaaac atcggttatg gtgcaatttt gtacgatgaa
     8581 gcccacaaac aaaaaattgc agaagaaaag caagcgtatt tgaaaaaaat gctattcgat
     8641 cttatattga gtacggtttt gactttgccg ttgatgttgt caatgattgc tatgatgtta
     8701 ggaagccatg cggcgattgt tcactttttt cattttccaa tcgtccagtt agtgctgtct
     8761 gctcctgtcc aattttatgt cggtgctcgt ttttataaag gtgcgtacca tgcaatcaag
     8821 acgaaagcac caaatatgga tgtattggta gcaattggaa catcggctgc ctttgcattg
     8881 agcatttaca acggattttt ccgtggacac ccccaagatc tttattttga aagcagcagt
     8941 atgatcatca cgctgatttt gctcggcaaa tatttggaac atacagcaaa aacgaaaaca
     9001 ggtaatgcaa tcaaacaatt gatgtctctt caaacaaaaa ccgcccaagt gataagaaac
     9061 gggaaagaag aaacgttagc gattgaagaa gtagtcgttg gtgatcaact agtcatccgt
     9121 cctggtgagc agattccagc agatggtcga attatttcag gaagcagtgc gatagatgaa
     9181 agtatgctta ctggtgaaaa tcttcctgta gaaaagaatc cggatgacac gctttttggc
     9241 gggacaatca atacgaatgg tctgctacac atggaagtca cacaagtcgg caagcagaca
     9301 gtattagcgc aaatcattca aatggtggaa gatgctcaag ggagcaaagc cccaatccaa
     9361 aaaatcgcag atcggatctc agggattttt gttccgatcg tattagtcat cgcgtttatc
     9421 acgctcatag ctacaggttt gatcactggt gattggcaac tcgcattgat ccatagtgtc
     9481 tctgtattag tcattgcgtg tccatgtgca ttaggtttag cgaccccaac agctattatg
     9541 gtaggaacgg gtgttggtgc acgaaatgga attttaatta aaggcggaga agcattagaa
     9601 gcagctgctc acttagacag cattgttttg gataaaactg gaacgattac agaaggaaag
     9661 cccaaagtta cagatctagt cggttcaaaa gaagtcctat ctatttttta tactttagaa
     9721 caagcttctg aacatccact aggtaaagca atcgtggaat acggaaaact gcaagaagca
     9781 gcaacatacg atatgattga ttttacagcc cacccaggtg ctgggatcag cggtacgatt
     9841 aatggagtac gctattttgc gggtacacgt aaacgattaa ttgaattgaa cctatcattt
     9901 gatgaatacc aagaacacgc gttagaatta gaacagcagg gaaaaacagt catgttttta
     9961 gctgatgaaa agcaagtgat cgggtggatt gccgtggctg atcaaatcaa actagaagcc
    10021 aaacaagcaa tcaagcagct ccagaataaa ggattagatg tttttatgct gacaggagac
    10081 aacaaactgg cagccgaaac gattggtaaa caagttggta ttgatccaaa gcatatcttt
    10141 gctgaagtac ttccagagga taaagcagcc tacgtagaaa aacttcagaa agatggcaaa
    10201 aaagtcggta tggcaggcga tggaatcaat gatgcaccgg ccttagcatt agctgatgtc
    10261 ggtatggcaa tgggaagtgg aacggacatt gcgatggaaa cagccgatgt gacgctgatg
    10321 aatagcagtt tggcatccat tgcacaaaca atcgagttgt ctaggttgac attgagaaaa
    10381 atcaaacaaa atcttttctg ggcttttgtc tataatacga ttggtattcc ttttgccgca
    10441 ctaggctttt tgaatccaat cattgcagga ggagcgatgg cgtttagttc cgtcagtgta
    10501 ttgttgaact ccctgagctt aaatcgacac atgaaaaagt aagagaaggg atggagtaaa
    10561 aatgaatggg aacgatatgg agaaaaaaca tgagcataaa aaagaagtag taaacaaaga
    10621 aagtacagaa tctcatgaaa aacagatgga gatgaaacat gaccatagtc agatggatca
    10681 ttccatgcac atgggacata accatggaga tatagcaaac agcaaacaaa tggaccattc
    10741 gatgcacatg gatcacgaac acggcggcat ggatcattcc atgcacatgg ggaatttcaa
    10801 acaaaaattt tggctatcgc ttatcctagc tatcccaatc attctttttt caccaatgat
    10861 gggaatggaa tttccatttc aagtaacgtt tcctggttct gattggctcg tattgatctt
    10921 agcaactata ctatttatct atggcggtca gccattttta agtggagcta agatggaatt
    10981 gaaacaaaaa agtcctgcta tgatgacact gatcgcgatg gggattacag ttgcatatat
    11041 ttatagtgtc tattcgttta tcgcaaatct gctcaatcca catacacacg tcatggattt
    11101 cttctgggaa ttggctactt tgatcgttat tatgctacta ggtcactgga ttgaaatgaa
    11161 tgctgtgtcg aatgccagca atgctttaca aaaactagca gaattactgc cagaatcagt
    11221 gaaacgcttg acgaaagatg gaaaagaaga gacagtttca ttgaaagaag taaacgaagg
    11281 tgatcgtttg atcgtccggt ctggtgataa aatgccaaca gatggtgtaa tcttgaaagg
    11341 tgaaacaatt gttgacgaat cagctgtgac tggcgaatca agaggaatca aaaaacaagc
    11401 caatgacaaa gtgattggcg gttctatcaa tggggatgga acgatcgaaa tcgaagtaac
    11461 tggaactggt gaaaatggtt atctagcgaa ggttatggaa atggtgcgaa aagcacaagg
    11521 agaaaaatcc aagctagagt cattatctga caaagtggca aaatggctgt tttatgtcgc
    11581 attaattgtg ggtatcctgg cattcatcgc ctggttgttc ttgacagatc ttcctaatgc
    11641 attagaacgt atggtaacag tctttatcat cgcctgtcct catgctctag gtttagctat
    11701 cccattagtt gttgctcgct ccacatcaat agcagctaaa aacggattac ttttgaaaaa
    11761 ccgcaatgca ctggagcaag ccaatgatct agatgtgatc atgctggaca aaacaggaac
    11821 actaacagaa ggaaaattta ctgtaacggg tgtcgaagta cttgatgatg cgttcaataa
    11881 aaatgaaatc cttcaatatc taggagcctt ggaagcgaat gccaatcatc cattggctgt
    11941 tggcattatg aattatttga aagaacatga aatcaagcct tatcaagctg aaaatctaaa
    12001 aaatctttca ggagtcgggc tagaggcaac agtcaaaaaa caacaagtga aaatagttaa
    12061 tgaaaaagaa gttgagcgtc tcggattaaa cgtagaacaa gcattattga aaccttacca
    12121 agaacaagga aataccatca gcttcctgat tttagaaaat catctagctg caatcgttgc
    12181 tttaggtgac gtagtaaaaa cagaagcaaa agaatttatc cgaacattga aagaaagaaa
    12241 aatcactcct gtcatgctta ctggtgacaa taaaaacgct gcccaagcag tagcagatta
    12301 tttagggatc gaagaatatt atggcggttt attaccagat gataaagaag ctgttgtcca
    12361 gaaatacctt gaccaaggga aaaaagtaat catggtgggt gatgggatca atgatgcgcc
    12421 aagtttagcc cgtgcttcaa tcgggatggc aatcggtgca gggacagata tcgcaatcga
    12481 ttctgcggat gtcgtattga caaacagcga tccaaaagat attttgcatt ttcttgatct
    12541 agccaagcaa acgcgaaaga aaatgatcca gaacctctgg tggggggcag gttacaatat
    12601 tcttgcaatt ccgctagcag ccggaattct tgcgccaatt ggtatcatat taagtccagc
    12661 agttggtgct gtcttgatgt cgttaagtac ggtagttgta gctctaaatg ctttgacatt
    12721 gaaaatcaaa taataatgaa aaaa
//
LOCUS       DBBGSZ010000061        12735 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.064, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000061 DBBGSZ010000000
VERSION     DBBGSZ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.064"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            97..540
                     /locus_tag="ACIZE5_002518"
     CDS             97..540
                     /locus_tag="ACIZE5_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGC6109622.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(546..1730)
                     /locus_tag="ACIZE5_002519"
     CDS             complement(546..1730)
                     /locus_tag="ACIZE5_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HGC6109623.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            1998..2696
                     /locus_tag="ACIZE5_002520"
     CDS             1998..2696
                     /locus_tag="ACIZE5_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGC6109624.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2703..3380
                     /gene="nth"
                     /locus_tag="ACIZE5_002521"
     CDS             2703..3380
                     /gene="nth"
                     /locus_tag="ACIZE5_002521"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HGC6109625.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3506..4039)
                     /locus_tag="ACIZE5_002522"
     CDS             complement(3506..4039)
                     /locus_tag="ACIZE5_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109626.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4336..6717)
                     /locus_tag="ACIZE5_002523"
     CDS             complement(4336..6717)
                     /locus_tag="ACIZE5_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HGC6109627.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6707..7354)
                     /gene="recU"
                     /locus_tag="ACIZE5_002524"
     CDS             complement(6707..7354)
                     /gene="recU"
                     /locus_tag="ACIZE5_002524"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HGC6109628.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7418..7957
                     /locus_tag="ACIZE5_002525"
     CDS             7418..7957
                     /locus_tag="ACIZE5_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HGC6109629.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8047..8466
                     /gene="gpsB"
                     /locus_tag="ACIZE5_002526"
     CDS             8047..8466
                     /gene="gpsB"
                     /locus_tag="ACIZE5_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HGC6109630.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8488..8855
                     /gene="rnpB"
                     /locus_tag="ACIZE5_002527"
     ncRNA           8488..8855
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACIZE5_002527"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9064..10230
                     /locus_tag="ACIZE5_002528"
     CDS             9064..10230
                     /locus_tag="ACIZE5_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HGC6109631.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10276..11772
                     /locus_tag="ACIZE5_002529"
     CDS             10276..11772
                     /locus_tag="ACIZE5_002529"
                     /EC_number="3.4.17.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HGC6109632.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11853..12536
                     /locus_tag="ACIZE5_002530"
     CDS             11853..12536
                     /locus_tag="ACIZE5_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGC6109633.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            12545..>12735
                     /locus_tag="ACIZE5_002531"
     CDS             12545..>12735
                     /locus_tag="ACIZE5_002531"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109634.1"
                     /translation="MTEVVSSKIFRIIFRKSYFWNTVYQEVVSLPFSSESQGTISKNS
                     FSCLMNIVTCDSELAGEHR"
BASE COUNT         4272 a         2230 c         2630 g         3603 t
ORIGIN      
        1 tcttggtttc agattgggtt ttcctacaaa atatttttat ctttgttgaa taggaaacaa
       61 aaaaacaata taatgaaaga aaaagaaggt gtagaaatgg ataaaagaca actgctaata
      121 gaagaatatc tggatttagc taatgagatt attcatcgta ataaaccaga aatggaaaaa
      181 gaatttgcag gatttactct aaatgaacta gaagtgattg aacatatcgg gaaaatccct
      241 gatcctaacg tgacaaaatt agcgaatgct agttacatga ctagaggagc catcagtaag
      301 ctaacaaaaa aactgatagc tagagggatc ataaacactt atcaaagcga agagaataaa
      361 aaagaaatct attttcaatt gacgccaatc ggacaaaaaa taaggaatag acacgagcaa
      421 ctccatcaaa aatgggtaca gcgagatgct actgtatttg aaaatatgtc aaaagaagaa
      481 tttgacacag tatttcgttt tatcggtcga tacagagaat ttatacgaag tagcaaatga
      541 agctactatt ttttattgta gtgataatag gcaaaaatca taagcaaaaa tccgaatacc
      601 gtcggaagaa atggtgctgc agcataaagc tgtcctgcga ttagcgggcc gatgacgcgc
      661 gatagagatt gtatactttg ggtaccgccc attacaagac cttgctggtt atctgagaca
      721 gaattggata gttggccatt gaatacagga gtaaaaatag aatcaccgaa accataacag
      781 ataatcccaa ataaaaacaa aatcggcagt agaagaattc cagataatgt gatgaataga
      841 taggcgagga tttcactgaa catccctatt cttgtgatct gctgttctga aaattttttg
      901 agcaatcgag gcataatgaa caattgcgag acagtatcca agattccaat caaagagaag
      961 cttaaaccaa ccaacccagc cttccactga aaggcgtcaa tcgaaaattg agaaaagata
     1021 gattgaagag agccagctgc caaccaaaca gcaaaacctg ctgtcaataa aggaataacg
     1081 gatgaaatct tgaataattg ttgtaattgg tgaaaaggtc ttacatggga gaaacttaaa
     1141 tctactgaac gtttttttat tggaaggctt tctagcataa atgtgtagcc ataaacggca
     1201 tttaagaaag taaagagtgc tccaataaat ataggaacag aattccccaa ctcagctaat
     1261 agacccccta taataggacc cagcgttgtt cctataccga ctaaagcacc catccatcca
     1321 aaaactttgg ttctttcatt aggttccgtg atgtcggcaa agtaagcata taaggtggag
     1381 atttctcctg ccgtcaatcc ttcaatgata cgaccaagga acaacatcca tatcgaattt
     1441 cctaaaccaa aaagcaaata tccgatactt gatcctaata aactgataat aaggatcgga
     1501 tgacgcccaa aatgatcact taagctaccg agaatggggg cagataagaa ggcagctaga
     1561 gcataaacag acatgagcaa agtgatatag aaagcttgct gatgtatgga gtgagaataa
     1621 ggcagcgtta aaaacggaag tacaggactg acgatagtaa atcctaatcc agtgaataag
     1681 acagagacgt atccaaaaac tttagaatgt ttatttgtga aactgtacat gtaaaaactc
     1741 ctttatgcaa taatgttaac ttggaaacaa aaatagtgta tagtaatttt gtttccttgt
     1801 caacattcta aggaacagcg aaatctactt aatttattta ttccgaaaag tgaagatacg
     1861 catcaaaaac atgaacaaac aaaaatcaag tagacgacat tgtaaatctg accgatcagt
     1921 gaagtaaata gaaaagaaac ctgttcttgc ttcccatgtt ttttttacgt atactgtgat
     1981 tgagcggagg agaaatcatg ttgaatttag aaaattactt aagcgctgga caaacagtca
     2041 tatctaatct tttacttaaa aattatcata ggatcggtct acaatctgaa gaatttttat
     2101 ttgttctaca gttgcatatg gcacagcttg aaggagatac tttccctgat ttgcagatga
     2161 ttgctatgga tatgggaatc aaacaagatc agatttttca aatactggat cgtctcgtaa
     2221 caaatggatt tatcaagata gaaacgacga ttgtcaacgg taaaaaagca gatcgatata
     2281 atctttaccc catctatgat ctattaggtg agtatttaaa aacacaagaa aaaaaatacg
     2341 aagaaaaaac acaagaaaaa gaaatccagt cagtgtatca attatttgaa caagaatttg
     2401 gacgcccgct ttcttcgatc gagttccagc ggatcggaca atggctagaa gaagaccatt
     2461 atcagccgga aattttgaag ctagcactgc gggaagccgt attaaatcag gcttatagtt
     2521 ttaattacgt tgaccgcatt ttgctatcgt gggaaagaaa aaatctacgt acaaaacaac
     2581 aagtggaaga agaccaaaaa cgaagaaaac agcagcttct tcaaagagaa gtagaacagt
     2641 cagctcaaca agaagaattg ccgaaagtct cactgaaaaa ttggttggag gagtagcgga
     2701 atatgttaag caaacaaaaa acaatggaag ctctagaaac gatgtatgga atgtttcccg
     2761 aagcacatgg agaactcaag cacaataatc catttgagtt attgattgca gtgatcttaa
     2821 gtgcccaggc gacagatgta tcagtgaata aagcaacgcc agatttgttt gcctcttttc
     2881 cgacacccga tgcgttagca gaagcttcaa tcgatgaaat cattcttaaa ataaaaacga
     2941 ttggtttgta tcgaaataaa gcaaaaaaca tcaaagcgtg tgcacagcag ctgattgaac
     3001 gtttcgatgg gcaagtgcca acgtcaagag aagaattgat gtctcttcct ggtgtaggca
     3061 gaaagacagc aaatgtcgta ttgggggatg cattcgggat accagcaatc gcagtagata
     3121 cccacgtgga acgtgtctca aaacgcctga ggatctgcaa actagatgct acggtcatgg
     3181 aagtagaaga aacactgatg cggaaagtac cacaagaatt atgggtaaag acacatcata
     3241 cactgatttt ttttggtaga tatcattgca cggcaagaaa tcccaagtgc gaggtatgtc
     3301 ctttgctatc aatatgtcaa gatgggaaaa atcggatgcg tctaaaagaa aaggcgctaa
     3361 aaaagaaacc acgcctgtag acgtggtttc tttaattgca aataaatgta tgaattatct
     3421 tgttattatg gagaaaagct gtttcgttta tcttttttgc atgaaaaagt aaatgtacat
     3481 actcagtagc taggatggta acttattaca atttattgcg ataaaaataa aagttgttat
     3541 ttttattggg aaaatacccg atgtagaaaa taatgccttc caatatacct ataaaataag
     3601 tccagtattc caaaggatta tataaataag tgacgtatct atctaaaggt gtaataaaaa
     3661 tgataagtga taataaaaaa ataccattta taactaaaca taaactaatg gatttgggcg
     3721 gtttcaggct catcagaaaa atatagattc tggtgaacaa caaccataaa aaagtgagaa
     3781 tcattgcatg agagcttctt tccataaatt ttcctttaag agtagtgctt aaaagtacag
     3841 aaaaaataat aaatgcaagg ataggagcaa ttaaagtaaa tttatttaat aataaacaaa
     3901 atttttcagc ttttttattc ttggaataac gaggtattgt tttcgataaa aaaagatggt
     3961 gcagacaaat tatgataatt aagcatacta tcagataact caaaatgaag ccttctttca
     4021 aaaaattatt caaaaccata tattgtattt tttatttgat aataacaatg ggattattaa
     4081 gaagtggcac taaataaaag actagtgtgt atttagccga tttaattata aacaagtaaa
     4141 tggataaagt atatgtaatg ataaaagaaa aatggatttt ctaattttta agctaaatgt
     4201 tagatcacac atgtatatgc tggatagtct tataaaaaat catgtaatac agcttggtac
     4261 atgattttta tttgtagctg ttttttacat agacacaaaa aagaaaccac gcttgtagac
     4321 gtggtttctt ttttactatc tgtttccaga agctgaggtg ctgctggatg gtgtatggtc
     4381 atttgcagca tccgctccgc tagttgctgg ctcactggaa gaagcaggag gagcagatga
     4441 agacggtgtc gagctttctt cggatgaaga agaaggaacc gttgttgaag acgctggctc
     4501 gcttgtttct gctgtcgtgc tttcttttga ggactcagca gttgattcgc tttgactagt
     4561 agagctagag ctttgagtcg ttgtctctgt tgttgagctt ccaggagtct ggacatagct
     4621 ggaagatgga atagttgttg atggtgtaat tgcattcgat ctagctgtat attgatcttt
     4681 gtagtacagt tcaccgccca cacgaattaa tccgcttggc atctcccagt ctgtatttgt
     4741 cacgttagct gaaacatact gcataagctc gcgataaaca tcagaggcta cgtgtgacga
     4801 ttctgaagtg acaggcgtca tttttttatt gtaacctgtc cacacggaaa tcgaataatt
     4861 tggcgtatag cccgcaaata ggatatctgg atacacccca gaagaaatac caagttttgc
     4921 atactcgtca tctgtgtaat tggatgttcc ggtcttaccg gcttgatata acccagcgat
     4981 ttgcgcattc gtaccagttc cttcagtgat cgtatctttt aaaatgtctg tgatcatata
     5041 agctgtttct ggagacatgg ctgtttttcc atctggctca taagtttctt ctgttccgtc
     5101 ttggaagacg attttattaa catattgagg tttgtaataa gtccctccat tggcgaaagc
     5161 cgcataggct gctgccattt ttaaggaaga agctccgtat tttgtcccat cttgttcttc
     5221 cgtattacta gagatcgcat tcgattgatg gatcgtactg tattcgatcc caagattttt
     5281 taagaaagaa gccactttat ctgaaccgac ttcattgaat aatttgactg ctggaacatt
     5341 acgggataag taaagtgctt ggcgtaaagt aatggtgccc atatattgat tatcccagtt
     5401 tcctacagga gtcgaagtcc cttcatagtt atacggtgcg tcagtaatag tttttccagt
     5461 agaatatttc aaatattcaa aagctggtcc gtaatctgtg acaggtttca tcgtagaacc
     5521 aaaatcacgg gaagtattca ctgctaagtt gttgcctaaa gttacgtctt ctgcgatgtg
     5581 acgtccgcca atctgggctt ttactttccc ggtattggtg tcgataaggg tggaggcaac
     5641 ttgcatctcg tcgtctgggt aagagacata ctgatccgtg ttgacgatat catatagttt
     5701 cttttgggcg tccagatcca aattcgtata aatctctaaa ccgtctgtgt agacattctt
     5761 atctgttttt tcttgtactt cattgatgac ttctttgaca taattatcga cgatcttagt
     5821 attgtcatcg gattgagtta gttcttgcag accatccgtt accggtacat taacagcttg
     5881 atcatattct gtttgagaga ttttttcgtt ttgaagcatc gtatacaaaa cagtatctcg
     5941 tcttttcttc gcctgatctg gataaacata aggatcatag gcggaagggg cttgaggcat
     6001 cccagcaagc aatgctgttt gcggtaaaga aagttctgat aatttcttac caaagtacat
     6061 ctcagaagct gtctccatcc cgtacaagcc gtttgacata tacactttat ttacgtagta
     6121 ggtcaagatc tcttgtttcg attttttttg ttccaatctt acagccatcc acgcttcttg
     6181 ggccttgcgt ttcagagtct gatcctcggc actggtggag aagaaggaaa gtttgatcaa
     6241 ttgctgtgtc aaagtacttc cgccttgcag tccgccagag gtaaagttag agagggcaga
     6301 accgatgatc cgaatagggt caaccccgat gtgtttataa aaacggcgat cttctaccga
     6361 cacgatcgca tcttctaatg ttttcggtaa ttcattcgca gaaatttttt cacgcttttc
     6421 tgcgcctaaa tcttcgaata gttcgccatc ttgtgtatat agtttggaag atacggtagc
     6481 gtctaatttt ttatccgtca attcgggcgc atcttttgcg taataccaga aaagtcctac
     6541 acctgctaaa aagaggatac agaaaaatga gagtattcct aaaaggatct tgataaataa
     6601 tcctttttta tgtgttccag aggactttcc agaacctttg ccagaattct tcttcacact
     6661 ctttttagga gtaggctgtt tctgtcgtct agagcttcta gtttgttcat ttgccattct
     6721 tgctttctcc ttcaatagat aatgttgata aatagaagtc aaccgcgtcc aaataaggaa
     6781 tccgcggaga aataccagtt ttgatctcta ttcctagttc ttcgatcaaa gataaaggta
     6841 gtgatttgcg tcctttttcc ttttgggcgt cccagtaagc aatcaaatga acactattca
     6901 aataaaaaca gcgcttcaaa gacgaaaacc ataacaagac aaagcagacc ccattttgtt
     6961 cgaggcatgc tttcatatgt tcgatttgat gggcatggaa gtttttaaag ggaaaagatg
     7021 ttttgttctt ggtttctttt gcttcaaagt ccaagtaaaa gcctcgatag acgccattat
     7081 agtctgtagt tgaggcttgg gtaaagtagg cttccttgat cacagcagca cttctcttag
     7141 gatagtctac tttcacgatt tggatagggg taggcttttt atggataacc gccaacccgc
     7201 gggaaagata atatttatta ctttcattga ttgcttcttc aaagcgcatc ccccgattgc
     7261 cgaattcagt gatctgattt cttttttctt gaattttttc gacgggagag gcattcttat
     7321 aataaggttg gccatttgga tagcgcaata ccatctttaa tcacactcct aggccacatt
     7381 atagcaaaaa agcggataga aagaaaagga atctgagatg gataagtcaa aagtaatcta
     7441 tgtgtctggg tatcgaagtt tcgaactcgg tgtttttaaa gaaaatgatc ctaaaatcca
     7501 agttgttaaa aatgttttaa aaaaagaact ccatcagtta gcagaagaag ggctggaatg
     7561 ggtacttgtc agtgggaatt tgggcgtcga actatgggct gtgcaaatag tagcggaatt
     7621 gaaagaagaa tatccggaac tatctcttgg tattttgtat cctttttctg attttggtaa
     7681 taactggaat gaagggaacc aagaaaaaaa acaattagca gaacaattag cagattatgt
     7741 cgaagctgtt agccatcaac cctaccaatc acctagtcag ctaaagaatc acactcgttt
     7801 tatacttgag catacagtgg gctgtctgct gatctatgat gaagaattcc ctggaaaaac
     7861 gaagtatttt tttgaagatg cacagaatta ccaagcagat catccctacg aaattcggct
     7921 gatcagtatg gacgatcttc aaaattttag tgaataatcg atattgtgtt tgatttatca
     7981 acttttttcc tatacaatga aaaaggtaga aatgttatta cgtaaatgaa aactagaggt
     8041 gtaaatatgg cgaatttggt ttatagtcct aaagacattt tacaacaaga attcaaaaca
     8101 aaaatgcgcg gctatgatcc cgttgaagtt gatgaattct tagacaatat catcaaagat
     8161 tatgaaactt acagcaaaga actccttgct ttacaagaag aaaacgatcg attgagtgca
     8221 aaagtagctc aattatctaa aactcaagga gcagctcaaa cacgcgtgca acaaacagag
     8281 gcaccaaaga gcgcagcagt gaccaatttt gatatcttaa aacgcttgtc aaatcttgaa
     8341 cgtgaagtat ttggtaaaaa gcttgatcaa caagcaagtg cagtcaaacc agcacaacct
     8401 aatccaaata actacacaaa tgcagacaca agcttagatg ataatgaaaa aacacgtcaa
     8461 ttttaatttt tgattaatga atttgcggtt ttcgggtaat cgcggtctga cttgatcagg
     8521 ctgaggaaag tccatgctcg cacaggctgt gatgcctgta gtgttcgtgc ttagcgaaac
     8581 cataagctaa ggtactcttt ggagtaacgg caggaaaaca agctaaggct tcggctatgc
     8641 ttaagtatcc ttgaaagtgc cacagtgacg aagcggctgg ggaaacccat ccggtggaac
     8701 gcggtaaacc cctcgagcga gcaacccaaa caatggtagg ggcgcttttt gtctggaaga
     8761 agaacaggac aaaaaggcag tataactgca gatagatggt taccgctttg ttttttctcc
     8821 ctggaaaagc aaagtacaga acatggctta tagaaaaccg caaacatcag ggaattaggt
     8881 cgtgacaaaa gtaatgcgtt ataagaaaca agaaaaacat ttgaaagcta tttttcaata
     8941 cttcagatga atcgttctta ttacaaaaca aacttttgta tcaccggtta ttcggaattt
     9001 gagtaaaagt gtggggtagg actgatgtcc cacctccttt ttttataaat aaggagattg
     9061 tgtatggaaa aaaacaggaa gttcaacctc gtcgcaactg cggcaagcgg gctagaagca
     9121 ctggttggta aagaattaag agatcttgga atcgaatgcc aagttgagaa cggacgtgca
     9181 cgttttgaag gaacaatgga aacgatcgct acagctaatt tatggttacg tacagcagat
     9241 cgagtaaaaa tcgtggttgg ggaattcgat gcgtatacgt ttgatgaatt gtttgaaaac
     9301 gtaaaagcat tgccttggga agattttctt ccactagatg cagcttttcc tgtagctgga
     9361 aaatcgatca agtcgaaact atatagcaca cctgattgcc aagcgatcac aaaaaaagca
     9421 atcgttgaac gtctccgtac ctattatcac cgtccagctt ctgtaccact gacggaaact
     9481 ggcgcacatt ttcagttgga agtagctttg ctgaaagacc atgtgatggt aactctggat
     9541 acgacaggac caagtttatt caaacgtggt tatcgcttag aaaaaggtgg agcaccattg
     9601 aaagaaaaca tggcagcagc acttattatg ttgacaaatt ggcgaaaaga ccgtccattt
     9661 tatgatcctg tatgtggttc aggtacgctt tgtattgaag cagccttaat aggccataat
     9721 atcgcaccag gattcaatcg tgagtttgct tgcgaatctt gggattggtt cagtcaagaa
     9781 atcatggaaa atgttcgatc agcagccgaa gaaaaagcag attatgatat tgaattagat
     9841 attactggtt cagatatcaa tggacggatg attgaaattg ccaaagccaa tgcagaagaa
     9901 atcggattag gctcttcgat tacctttaag caacaagcag tcaaagactt caaaacggat
     9961 aaagaatacg gggtcatcgt ggctaatccg ccttacggag aacgtctagg agaagaagaa
    10021 actgttcgga aattatataa agaaatgggc gatgtattcc gtccattaaa aacatggagt
    10081 aaatatatct tgactagcga cttagcgttt gaggaatttt acggacaaaa agcaaccaaa
    10141 aaaagaaaat tgtacaatgg tgcattgcgt acggatctat tccagtattg gggaactcgt
    10201 ccgcctagaa aaaaagagaa agacgaataa tcttactaat tgattcattc aattggatgt
    10261 ttggaggaat agggaatgaa agaaaaagag tttttacaag aagtaaaaga aatcaatctt
    10321 ctacaacaag ctttaggaat cctcgattgg gatacacaaa caggtatgcc tgaaaaagct
    10381 agtgcatacc gaagtgaagt agacagctat ctttacagca tttatttttc aaaaaaaatc
    10441 ggtccaaaaa tcaaagaagc cattcgctat ttttctgaac atccggaaga attgtcggaa
    10501 gttggaactg ccgtttttgc caaagtaaaa gaagagtatg atttggaaca tcgcgtaccg
    10561 gaagatctta tgagaaaata tacagctgcc gtttcttcag cacacggaca atggcaaaaa
    10621 gctagagaaa cacaacaatt ttctgatttt caacacgcat tgaatcaaaa tattgaatta
    10681 acaaaacagt tgatacctta ctggagaaaa gatgaaaaga cgaattatga tgttttgctg
    10741 aatcaatacg aacccgggat gactgtcgaa atccttgata aggtatttga tcagcttaaa
    10801 gaaggaattc tttcgatccg ccgtacgctc caagaaaaag ggactgaacc tgaaacagac
    10861 tttttaaatc ggagaatgac gaaaaaacaa cagaagagat ttgtagtgaa agtaatcgaa
    10921 caacttggtt atgattttag tcgtggtcgt ttagatgaca ctgtccaccc atttatgact
    10981 ggaattaatc cgaatgatgc acgaatcacg acacgatgga acgaaacaga tttcaaaatg
    11041 gctgtttttg gagtgatcca cgaggctggt catggtatgt atgaacaaga catcgatgat
    11101 aaatatgcgt atacaccggt ttatgaaggt acatcaatgg gtatccatga atcacaatcg
    11161 ttgtttaacg agatcattat tggaagtagt cgcagcttct ggaaaaagca atatcctttc
    11221 tttcaagaat gtgcagaagg aacattcgat gatattcctt ttgacaaatt ttatcgttca
    11281 ttgaaccata caaaatcaag tttggttcgt atcgaggcag acagtttgac ttaccctctc
    11341 catatcatca ttcgttatga aatcgaaaaa atgattttca atgaaggggt agatgttgct
    11401 gaactacctg aaatatggaa tcaaaaatat gaagagtatc tgggaatacg accaacaaat
    11461 gatgtggaag gcatcctaca agacgttcat tggtcaggtg caagctttgg ttattttccc
    11521 tcttatgcat tagggtacat gtatgcggca caattacttc attctttgca gcaagaaata
    11581 gatgtggaaa atgttctagc gtcagacgat tattctccaa tcaaaaactg gatgtcagag
    11641 catatccatc aatatggtgc atctagaaaa ccaaatcaat taatcatgga tgcaacacat
    11701 gaaccgctta atccgcaata cctgatcgac tatatgaaag acctgtattt taatgtatat
    11761 caggtaaaat aaaatacaat ttacaaagat agctgaaatt catctaatct atagatgttt
    11821 tcagctattt acttaagaaa gaagtggaac gaatggataa attacaagtg atcgctgatt
    11881 atagtatgga ccaattagcg catgatcaaa caggacatgg gagcgatcat accaaaagag
    11941 ttgtcaagtt agctgaaaaa attttggaga cggaaccgca ggcagaccgc tttgtgacgc
    12001 ttgcagcagc ttacctacat gatacgattg atgataaagt cgttaaaaat gagaacgagg
    12061 caaagcaaca gcttcgtgta ttccttcgct ctttgccaat agtagaggaa cagatctcga
    12121 tgattttttc cattatcgaa aatatgtcct tttctaaaaa tctctctgaa gcggccgaac
    12181 tatctctgga aggtaagatc gttcaagacg ctgatcgtat cgaagcatta ggagcaatcg
    12241 gcattttgcg tactgcttat ttcggcggtg gacatgggca cccgattttt gatcctgaac
    12301 tgtatccgca aacattcaag gacaaagaaa attaccgaaa aggcacgaca gtgatcaatc
    12361 atttttatga aaaactgttc ttgctgtctg ataaaatgaa tactgattac ggatatgaag
    12421 aagccaaacg aagagaaacc ttcatgcgtg aattcttaga agaatttttt ctggaatggt
    12481 ctattgacga tgaaaatttt actccagaca attggatcaa aaataacaaa aaatgatgga
    12541 ggttgtgaca gaagtggtca gctccaagat atttcggatc attttccgta aaagttactt
    12601 ctggaacact gtttaccaag aggtcgtgag cctgccgttc agctccgagt cacaaggaac
    12661 aatttcaaaa aatagcttct cgtgtttgat gaatattgta acttgtgatt cggaattggc
    12721 aggagaacac cgttt
//
LOCUS       DBBGSZ010000062        12734 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.065, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000062 DBBGSZ010000000
VERSION     DBBGSZ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.065"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(87..266)
                     /gene="rpmF"
                     /locus_tag="ACIZE5_002532"
     CDS             complement(87..266)
                     /gene="rpmF"
                     /locus_tag="ACIZE5_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HGC6109635.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(324..893)
                     /locus_tag="ACIZE5_002533"
     CDS             complement(324..893)
                     /locus_tag="ACIZE5_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HGC6109636.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1079..1981
                     /locus_tag="ACIZE5_002534"
     CDS             1079..1981
                     /locus_tag="ACIZE5_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HGC6109637.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2016..3800)
                     /gene="pyk"
                     /locus_tag="ACIZE5_002535"
     CDS             complement(2016..3800)
                     /gene="pyk"
                     /locus_tag="ACIZE5_002535"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HGC6109638.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3874..4836)
                     /gene="pfkA"
                     /locus_tag="ACIZE5_002536"
     CDS             complement(3874..4836)
                     /gene="pfkA"
                     /locus_tag="ACIZE5_002536"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HGC6109639.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5004..8318)
                     /gene="dnaE"
                     /locus_tag="ACIZE5_002537"
     CDS             complement(5004..8318)
                     /gene="dnaE"
                     /locus_tag="ACIZE5_002537"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HGC6109640.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8549..8734
                     /locus_tag="ACIZE5_002538"
     CDS             8549..8734
                     /locus_tag="ACIZE5_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HGC6109641.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8796..9992)
                     /locus_tag="ACIZE5_002539"
     CDS             complement(8796..9992)
                     /locus_tag="ACIZE5_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HGC6109642.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10162..11598)
                     /locus_tag="ACIZE5_002540"
     CDS             complement(10162..11598)
                     /locus_tag="ACIZE5_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGC6109643.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11891..12700
                     /locus_tag="ACIZE5_002541"
     CDS             11891..12700
                     /locus_tag="ACIZE5_002541"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC6109644.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3802 a         2672 c         2250 g         4010 t
ORIGIN      
        1 atatttttta tttaccgact acaaaaaaat aaacctcaag gctccatggt tagccttgag
       61 gttttacatt ttctaattaa aatgtattaa gcttcttttg acattacgtc cttaccatca
      121 tagtaaccac aatttgcaca tacgtgatgg ctttttttca tttcaccaca gtttggacat
      181 tcgtttaacc ctttgattgt caatttgtag tgtgtacgac gttttgcttt tttagctttt
      241 gatgttcttc tagctggtac tgccattttg ctacacctcc ttgtaaagtc ttgtatctaa
      301 attagacaca atatattcca atcttacttg ttatcgtcgt cttttgattt agaatcaaaa
      361 agttcagata gttttgcaag acgaggatca attttattct cggcttcttc catttttctg
      421 cgctggtatt cttcttcgga aacaacttcc caatcattgc cttttggaag ttctgttgct
      481 gcttcctctt cttttgtcaa tacccgcatt ggaatcgcca ataagatgtt gtcttcaatc
      541 gactctgcta aattcaataa tggaccttca attagcaaaa tctcatctgc agacatttgt
      601 tcatctctac tttggaattg ttcttctgtc atgaatactt cgtctacaga aaaatccatg
      661 ggcagttcaa caggttctag tgaacgtgtt gaaggaactg tcaaagtcgt ctgcacagtg
      721 taatgaacga tatagccttt cttatcaact gagaccaaac cttcgacttc cactggcgca
      781 acatcaagta ttaaattgtc tcgcttcatg agagcggctt tcaagtcgag cgtctcatga
      841 aaagttaacg gtgtctcctg gtattttctc aattccaata aagaccattt catttttcat
      901 cactcctaag caacaaaagc aattatacag ggcaaaaagc atgttgtcaa tgaaattttc
      961 ttgacacctt gcagttcata aaaaaacaga aaaatcttta ttagaaagcc tctgtttgct
     1021 atcatcctca gaatcattta caataatcat tattccatta aaggagcgga tgatcttcat
     1081 gaacacgaaa gatatcgaat actatgtcca aatcgtcaaa caaaaaaatt ttacgaaagt
     1141 ggctaattat ttccgtgtga gccaacctac tattacatat gcattacaac gtcttgaaaa
     1201 agagtttgac accgtactta ttacaagaga tcgatcgcat cacgaattaa tcgtcacgcc
     1261 ttctggaaag cagctgtttc tccatgcaca aaccattctc caagagattt ctactgcaag
     1321 agctgaaatc actcagttgc aaaagaaaaa gcttcgtttt ggcatgcctc ctattatcgg
     1381 caatgaatac tttcctaaac tgtcaagtta ctttatcaag catgaattga tgaatcaaat
     1441 tgagattacc gatggaggct ctcgggactt atacgggatg atccgacaag ggaggatcga
     1501 tttagctgta ttaggctcaa cacagccaat cgtggatcaa tatttagaaa cagagttact
     1561 tttggacaaa cgtttcatga tcgtcgtgcc acctacacat cctctttcca agcaggatac
     1621 tgtctctttc aaagatatag cagatgaaca gtttgtacta ttgaacgaac attatgtcca
     1681 ccccgcagca ttcactaagc tttctaaaca aacacatact catccaaaag ttgtttatca
     1741 aagcaatgac ttgacgattt taaagagtat ggtccgagaa aatgtgggta tcggtttttt
     1801 ggcagagatt gctgtccatc ctgaagatca tttagtttgc ctccctcttt cagatgaagt
     1861 tcagcctcgc ttcttgattt cattggcaaa acgaacacag cagatcgtca cgcctcttca
     1921 agaacaagta gtccaagtta tccatgaatt cgttacagca caaaaaaaca gctcttcgta
     1981 aaagaagagc tgtttttatt ttttattaag ctaaattaga tagctgttgt ttcgccacgg
     2041 taaacgatgc cgcgacgtga atcaacggta atcaattcac cttctgtaat tgttgttgtt
     2101 gcgcctttag caccaacgat tacaggaata tcttgtgcaa ttcctacaac tgcagcgtga
     2161 gaagtcaatc cgccttcttc aacgataaca gcagctgctt tttcgattgc aggcatatat
     2221 tctttgtcag ttgatggtac aactagaacc attccgtctt ttgctttttt tacagcttct
     2281 tcagcagatg aagcaataac tgcatttgca acgacagatt tttgtccaac gccttgagct
     2341 tctaataatt tagaaccaat catttgaatt ttcatcacgt tagttgttcc gcgttcacca
     2401 actggtacac cagcagtgat caagattaaa tcgccttctg atgcgaaacc taattcaaca
     2461 gcttttttag ctgctagttc aaacatttca tcagttgttg atggtttttc agcaactgtt
     2521 gggtaaacgc cccagtttaa catcaaacca cgttttgtgc gttcgtcaaa agtaacagcc
     2581 aagatatctg catctggacg atattttgaa atcatttttg cagtgtatcc tgattcagtt
     2641 gcagcaacga ttgttttcac gcctagattt tttgcagcac gagctacaga taaaccgatt
     2701 gtttcagtta catctgtttt atcgaattcg ttcaattgga atgtacctaa ttctgataat
     2761 gcattttcag cttcttggtc gatacgtgcc attgttgaaa cagcttcaac tgggtagtcc
     2821 ccgtttgcag attcaccaga tagcattgtt gcatctgtgc catcaaatac agcgttagca
     2881 acgtcagaag cttccgcacg tgttggacgt gggttttctt gcattgattc taacatttgt
     2941 gtagcagtga taactgggat accagcagca ttacattttt tgataatgcg tttttgaacc
     3001 attggtacta gttcagctgg gatttcaaca cccatatctc cgcgggcaat cataacaccg
     3061 tcagaaactt tgatgatttc gtcaatgttg tcgatacctt cttgagattc gattttaggg
     3121 aagatttgaa catgagtcat gtctttttct tctaagattt cgcggatatc tagaacgtct
     3181 tgtgctttac gtacaaaact tgcagcgata aagtcgatat cgttgtctaa accaaaacga
     3241 atatcgtcag catcttttgg agtaatacct ggcaaactaa tagaaacgcc tggtgcattt
     3301 acccctttac gtgatcctag catacctgca tttttaactt ctacgactaa ttcacggttt
     3361 gcttcgtctt tttcaatgat ttgcatatcg atcaaaccat catcaaataa aatgtgtccg
     3421 ccaacgtgaa catcgtcaaa taatcctggg taagtaaccg cgattttttc ttttgaacct
     3481 acatgttcag gatccataga gatgcgtgtt tgatctccta cttcaaattt gatgtatcct
     3541 gcacgaccaa aatcagcttc tgttgtgcct tgaacagttg tacggatttc agctcctttt
     3601 gtatctaaaa gaataccgac atcttttcct gtctttttaa ctgcttcacg gaccatagtc
     3661 atacgtgata attgttcttc atggtcacca tgagaaaaat taaagcggaa gacatttgcc
     3721 ccagattcaa tcaattgaga aataatttct actgagttac ttgctggtcc taatgtacta
     3781 acgattttgg tttttttcat ttaaaaaact ctcccattca attttgttta tttaaagctg
     3841 tacacagctt aaatagcttg gtttctttca ctcttaaaat gaaagtgaat tatttagatc
     3901 atatagtgat aagtctggtt tatgtttgtt gttttcaagt gtatcaatga tgtcagacgc
     3961 aacgatttcg ttgtcatgga taccgacaca taatccacct tttccttctt gaagcaattc
     4021 gacagcgtaa gcaccgaatt tacttgccaa cacgcggtcg cgtgcgcttg gtgctccacc
     4081 acggacaacg tgtcccaaga tagatacacg tgtatgatag tcaccaaatt ctgaaagttt
     4141 ctcagcgaat tcatttccgc ccattacacc ttcagccaag atgatcaagc aatgtttctt
     4201 cccgcgatcg cggccttctt ggattttttt agcaactgaa gccatatcaa aatcatgttc
     4261 tgggatgatg atttcatccg ctccgccagc cacacctgac cataaagcga tgtctcctgc
     4321 attgcgtccc attacttcga taacgaatgt acgaacatga gaagtcgctg tgtcacgaat
     4381 acggtcaatt gattctagta ctgtattgat tgctgtatca aaaccgattg tgaaatcagt
     4441 cccaggaata tcattatcga ttgttccagg aatacctact gctgggaaac cgcgttttgt
     4501 caaagccatt gcgccatgat aagagccgtc tcctccgata accactagac cttcgattcc
     4561 gaattttttc aattgttcga ttccttttaa ttgaccttct tcagttgcaa attctggata
     4621 acgtgcagaa tacaagaatg taccaccacg ttggatcttg tcacctacat ctgccacatc
     4681 aagacgacga atatctccag caactaaacc ggcaaaacca taattgatcc cgtatacttc
     4741 cagtccttcg taaatacctt tacgaacaac ggcacgaaca gctgcattca ttccaggtgc
     4801 gtctccgcca ctggtcaaaa ttccgatgcg tttcataata aacattcacc tcattaaaat
     4861 actttatcct aagtatgact taggtttaca accatttttg cgttaaccac gactaacatt
     4921 ctaacattat ttttctcact tgtcttgatt tacggataaa aaaatgaaaa aaaatgaaag
     4981 caagtagtat tttttaccgt aagttatttg aaaaccacat tatcttcgcc aagcagataa
     5041 ataagttgcc cctttatact cttgctgtca tccacccaat aagcatctga cagaactact
     5101 tttcgttgcg ttttttcgtg atacataact actggtatat atcctgggtg tttctgaaaa
     5161 atcacttgta attgtttcat tatctcggga tcttcccgtt cttctgtaat acgcaaatag
     5221 caagtttgtg aaggatactg ggcttctaac tggttaggat cagcaaagct ttctccaatt
     5281 agttgcagtt cctgattata tttgctgatt tcgctccgcc cttgaacaaa gatcactcga
     5341 tcaacggcaa acaaattacg atatttacga taaagagttg gaaaaactgt gacagaaatt
     5401 tctccactac tgtcggttcc ttcaacaaag gccatcagtt ctcctttttt tgtccgaatt
     5461 tctctaactt ccttgatcat cactaataaa ttgactggtt gattagggac gatatctgta
     5521 atcagctgaa cttgtttagc taaacgaaga cgatcaaacc cttctgcagg atgacctgac
     5581 aaataaatac ctaagtactc ctcttccagc ttcaagcgtt cttctagtgt atagtcagcg
     5641 acttcttctt cttttaatgc catgattccc agcaagtcaa gacttccacc actgtaaacg
     5701 atattttgga tttttccttc gagatcaagc atcaattgtt tcctgttagg agataattca
     5761 tcaaaaactc ctactgctgt cagtgattgc agtaactcta atttcagcca acgcttatcg
     5821 atccgtatga ggaattgatc cactgactgg aacgggccat tttgttttct ttcgtttaat
     5881 atatcttcta caaaatcacg ccgaatacct tttatcgctg tcagtccgaa tctgatttct
     5941 tccttattga ccaactcaaa actggaatta ctttgattaa tggacggcga ggaaagtttg
     6001 agtttatttt tacgtgcttc tgcaatatat tctttcaatt ttgatgtgtt atgccgaaca
     6061 gaattcatca ggctggtaaa gaaagcacct ggatgatggg cttttagata cgccatttgg
     6121 aatcccacga atgaataagc aaatgcatgt gaccgattga atccatagtt tgcaaatttt
     6181 tcgatatatt catatacggt cgctgctgtt ttttccgaat atccctgttg taatgctcct
     6241 gatacaaaat gcgacttttc ttcatctaat acgtcttttt tctttttact cactgcccgt
     6301 cgcagaatat ctgactgccc taatgtaaat ccagccatag tcgaggcgat ctgcatgatt
     6361 tgttcctgat agacgatcac tccatatgtg tttttcaaaa tcgggatcag tgaatcatct
     6421 gggtagcgaa tggcttcttt tcctttcttc ctggcaatga aggtatctat attttgcata
     6481 gggcctggtc gatacaatgc attgactgcg gcaatatctt cgatgttttc tggatctaat
     6541 cttcgtaaaa cgttccggat accagcagat tcaaattgaa atactcctga ggtttcgcct
     6601 cgttgaaaca agagcagcgt ttttgcatca tttagcggga tctcttttaa tcggatctca
     6661 tacccttcta ctcgcttaac agctttcaaa gtaaaatcaa taatcgataa gttgcgtagt
     6721 cctaaaaagt ccattttcaa aagaccgatt gcttctacct cattcatcgt atactgggtc
     6781 agaaaagctt catcagaacc gcgttggagc ggaactagtt caagtagatt cttatcgctg
     6841 ataactacac ctgctgcgtg agtcgaaaca tgtcttggca atccttctaa aatcactgca
     6901 gttttgaata aaagttggtt tttttcgctt gcctgaacta attctactaa ttgatgcgaa
     6961 gttttataag cttgggtcaa tgtgattttc aattgattgg gtattgcttt tgaccagcgg
     7021 tttgcttcac tttgcgataa accaaacact ctagctgcat ctctaagaac catttttgct
     7081 gccattgtgc caaatgttgc gatttgtgcc atatgatatt gtccatactt ttctcgaaca
     7141 taattcaata cttcttcacg tcgattgtca ggaatatcca aatcgatatc tggcatcgta
     7201 aagcgttcgg ggtttaaaaa gcgttcgaac agcaaatcat attctaatgg atccacatct
     7261 gtgatttcta acacataggc tactaatgaa cccgcagcag aaccacgacc tgcaccggta
     7321 acgattttgt ttctatgagc aaaagccatt acatcccata cgatcaagaa ataatcatcg
     7381 aatcccattt gatggatgac agataactcg tagtccaaac gttcttggta ttcctttgta
     7441 tagtcagtga ttcggcgttc cacttgcgaa tagcataact ctcttaaata ttctccagct
     7501 tgttttccat taggaactgg ataatgcgga agtaatttct gatggaactg gaattcaaat
     7561 gaaatcgatt cagctaaacg ctgggcgcct attacagctt gggaaagacc cgctttttcg
     7621 aatcgtttga tcatttcttg ttctgaaaga agatagacat ttgctgttag tggtaaagat
     7681 gcagataaat tttctaaagg tatttggctt ccctctttga tatgtttcat cacttcaagt
     7741 gcaaaaagtt cttcttgttg taaactagcg atgggatgta atgcacaaag cgaataattt
     7801 tcttttatca catactgata ccattcaggc aattgatcag gcgtgttttc tgtcaagccg
     7861 atataaaaat ttctagtaaa aacattttca agtaaaaact gccaatgacc gaaaaagtta
     7921 tcctctttat tgaaagcctc agaaacagaa tgatttgccg gaacaacaaa cgctagatgg
     7981 tcggtttctg tcatttctgc aagttccaat ttttcttgga tcatttttcg gctggaaagt
     8041 ttcatcagct gctgataacc tatttcatct tttgcgtacg caagcaagcc ataatttttt
     8101 tcttcataag tataactaag atgtaatcca atgattggct gtactccttc ttctacacaa
     8161 atacgataga attcaggtgc accgtataag acatctttat ccgttatggc taatgaagtg
     8221 tagccttgtt tttttgcttc ttgtacatat tctcgaatac gtatcgtact ttgtaaaaga
     8281 gaataagaag taattgtata aagttgtggg aaaaacatct tgcattccgc cttttttttc
     8341 gttaaaattc actagcgtta aaaggtttga tccttttact ttcattaaga tagcaggcgc
     8401 tgaagttgat tattccactt catttgcttg cttgtaatct gtaggaatga gttctttcgc
     8461 aagaactcaa attttattga gatttggtct cgtttcttta cattcaaaga aaatctggta
     8521 aaattaagat agaaaagagg tgttctttat gcgatatatc gttacattat tctgggctgt
     8581 cgttctaggt caagtagtcg gttatattgg tgctgcatta acaagcggaa catatgattt
     8641 tactttgaca acaatcattt cattcattgc gggtgtcatt atccttttga ttggtgcagt
     8701 tgcgccaaga aaagaaacct ctgcccattc gtaaaaaaac agccaagagc ttgagatttc
     8761 tcaagctctt ttttattttc tactcctcac caccattata atctgctgcg aagaacttta
     8821 cgaaagttga ataaagaaag aagaatattt gacagaacaa acaaacttgt cacaataaaa
     8881 acagcactgt aattataagc atgcgcgact gtcgatccta gcatgggacc taaaacttgt
     8941 ccaaagttgc taaacatctg attgtagcta tagattcggc tgactccttc ttgaggcgta
     9001 atcttactga tcagtgtatt gacagaaggc atcaaagcgc cagttgaaaa gcctaaaata
     9061 aagcgaagta tacctaattg gagcggtgta gtgacgaatg ccataggtaa ataacagcaa
     9121 aatgataaaa tgagtcctcc aattagaact ttttgattcc caatcttatc ccctagtttt
     9181 cctagtttcg gtgaagaaaa gacagcggaa acaccagcta tcgaaacaat caagccgctg
     9241 acaaaaagga tattttctgt acttccgctc aattcacgaa tatataaggt caaaataggg
     9301 ctgatcgtag tgattcctat ctgtaaaatc aaggtcgtaa tgaagagacc gatcaaaata
     9361 gagagatgat ccatttttga aaaaatttct ttggtgctta tcagatcttt tttctcgatt
     9421 ggatggaaat cttctttgac taagaaaatg gtcaataccg ttgtgatcat caacaaagcc
     9481 cctgtgatca agaatacatt ttccatacca aaccactgag ccagtgcacc gcccattgaa
     9541 ggtccgatca gatttccagc aatcgctccg gtagacaatg ttcctaacgc ccatccgctc
     9601 ttttctctag gtgcctgtga agcaatcatc gctgtggcat ttggaatata tccagacaaa
     9661 atcccattcc aaaaccgcat gatcaaaagc caatacgcgt ttggtacaaa agccaaagat
     9721 cccattgtta atgtcatccc tgctgctgca cggatcatca tgagttttcg gccttttcga
     9781 tcagctagat ttccccagat tggtgcaacc acggcagatg caaaagcagt cacagagatt
     9841 gctagtcccg aaaacaattc gatttgatct tttggtgttc ctagttgctc aacataaact
     9901 ggtatgaatg gcataactaa actaatactt gcaccagtga aaaaacagcc aatccacgca
     9961 atcactaaat tttttctcca attaatctcc atctatcatc cctctttcgt ctcttttatc
    10021 atacctattt tcgaataaac aagcaacgat ctcgccagta aaaagagaaa aatcccgcaa
    10081 aggtcatttt atatgtaacg ttctttttat gtaaaacaaa aagagatcag aacaaatact
    10141 gttccaatcc cttctcttta gttaaattgt tgctagaatg atgaagttga taatgaataa
    10201 aatatcaacg atccacaaag caacagaaac ttgattgtat tttcctttga ttactttcac
    10261 aattgtatag aaaataaatc ctgctgcaat cccataggaa atgctatagc acaatcccat
    10321 aaagatcgat gcaaagaagg ccggtaaagc ttcttccata tctagccatt tgatgtctgc
    10381 aaaagaagcc atcatcatta ctccaactaa aatcaatgct ggcgcagttg cttgatttgg
    10441 tacaatggcg atcagtggag agaataaact acttaatgcg aatagcactg ccactactac
    10501 tgaagtcaaa ccagtacgtc caccggcccc gatcccagct gcagattcga cataagttgt
    10561 tgtattcgat gtaccaaaga tagcccccac agaagtagcg atcgcatcgg caaatagtgc
    10621 tttatccatt tttgttttga acccacgacc atcttccaac gcgatctcgt cttcttttga
    10681 gaaaatacct gtgcggcgtc ctgtaccgat aaatgttccg atcgtatcga aagtatcaga
    10741 taaactgaat gcgatgatcg tcatcaatac ttgaggaatc ttggaagaat cactgaataa
    10801 agattgcatg ccttcagaac caaatgctgc accgaaagtt gttcctaatt ctttaaatga
    10861 attacctaac gaattcgttt gccaatcaat ggaacttaaa tcaacaacac ccataaaaat
    10921 accaaggact gtggtcgcta cgataccgat aagaatagcc ccacggacat tttttacaac
    10981 taaaatggct gtcagtacca aaccaatcac agccaataag ataggagcgt tgtcaaagtt
    11041 ggctaacgca gggacgattc caccatttat cgtaacattt gtcgcttttc cgccttcaac
    11101 gacagagctc gaaatagctg actggtctgc tgaaaaagat aagaatcctg catttttgat
    11161 tccgacatac gcaacgaaaa taccgatccc gccaccaatc gcatgttgaa gactttcggg
    11221 aatcgcccga ataatcattt ttcgaatatt tgtgacagta ataaaaatat tgattaatcc
    11281 gcaaataaac accattgcca aggcttgttg ccaagaataa ccaagcccaa aaacgaccgt
    11341 aaaagtgaaa aatgcgttca atcccatacc aggtgcctga gcatatggta catttgcgaa
    11401 caatcccatt accagcgtac caataatcga tgcaatgatt gtcgctagaa atactgcttg
    11461 gaagggcata cctgatgctg acaaaatcgt cggatttacg aataagatat aactcatggc
    11521 aaagaatgtc gttactcccg ccattatttc agttgataca tttgtattgt ttttctttaa
    11581 accgaaaaac ttttccataa aaagttccac tccctgaatt tttttctgat ggaaaactat
    11641 aataataaaa aataagtaaa atagggcaaa tccatcgaac aatttcaaat tatatagacg
    11701 tttcattcgc ttttcaacgt ttttttaaca aaaaaagcga aaataatact taacgttcgt
    11761 gtttagctta tgtttagcta tttatatagc cataactgta gtttttgtta ggaatagctg
    11821 attgctcttg ttaattacct aaaatatgct agactaaaac aaatgctagt tgaggaagga
    11881 aggaccctta ttgaataaaa aattaattgc catcgatctg gacggaacta ccctcaatca
    11941 agattcgatg attacatcta aaacaaaaga gactctaaaa aaagcaatca atgccggtca
    12001 tcatgtcagt attgctacag gacgcccatt ccgaatgagc catcagtttt accaacaatt
    12061 agaattaaca acaccgatgg ttaattttaa cggcgcatta gtacacatcc ctaatcagca
    12121 ctgggatggt gaaagagaaa cgttgatcaa tcgtgaaatc gcttttgaaa tcttatcgca
    12181 aaaaaagcag ctaaatttag attttatcgc tgctgaaaat cgtgatactt tttttattga
    12241 cagttttgat ttctttgatg aaaaaatttt tgcttcttct cgtccaggag agaagaattt
    12301 gctttctcct aaaaatttga cgacaaatcc tacatctttg cttgtccgaa cagacaaacg
    12361 ttttgcagga gctgtatctg ctgaattaac acgtcaattt ggcagttatg tcgatgttcg
    12421 gacatggggt ggacctactg ccatcttaga gattgtttca aaaggaatcc aaaaagcaaa
    12481 aggcgtgcaa gagattgcta actacctgtc tatcgatcaa aaagacgtca ttgcctttgg
    12541 tgacgagcat aatgatttgg aattgttgga ttatgcaggt tggggagtag ctatggctaa
    12601 cggtactgac caactcaaag gcattgcaaa tgatgtcact cctttgagca atcaggaaga
    12661 cggtttagct gtttatctgg aaaaactact taaactataa tagagaatta gattccacaa
    12721 aaaagaggtt gtga
//
LOCUS       DBBGSZ010000063        12494 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.066, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000063 DBBGSZ010000000
VERSION     DBBGSZ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.066"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            158..730
                     /locus_tag="ACIZE5_002542"
     CDS             158..730
                     /locus_tag="ACIZE5_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HGC6109645.1"
                     /translation="MTENKATQERTPQERLQEEQEHKEHVHHTKINAAAIADHLLGNM
                     HTLHVKLHQYHWYVKGANFFTLHEKFEELYNENEKWFDKLAERLITSGHKPASTTVEF
                     EKYSMLSEDAVNKYAKAEDMVENIIEDFRSTRDLTIRAIRLAQDEGDDALEDTLIAFK
                     NDLDKNIWMLQAFIGKEALEDDDALDEDED"
     gene            875..1579
                     /locus_tag="ACIZE5_002543"
     CDS             875..1579
                     /locus_tag="ACIZE5_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011476586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HGC6109646.1"
                     /translation="MTKHTHHEIGDHAACIRLVPIFNHLEDSAMNYIAEKAHTKQYQK
                     GEFLFRSQEKEDTLYIINRGKIRIYRLADSGKEQLVRILNPGDFTGEWTLFNPDAVHE
                     EYAEATRDTVVCMIQQKDVQDFLEQYPAISLKLLAEMSKRLESSERQTTQVAVESVIT
                     RLVLFLAENVEPEMGNSPTITLPMAKKDIASYLGTTPETISRKFGELEDEGLIQQLSG
                     KRIKIQDLDDLLLYSE"
     gene            1807..2145
                     /locus_tag="ACIZE5_002544"
     CDS             1807..2145
                     /locus_tag="ACIZE5_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109647.1"
                     /translation="MHCFWVIVAITLSAAGAFFVVPFTKNTIGGEAKTSNVVEADRLA
                     MEKEEEVVKGAGVIGHGKVAYYEASDQGDKSVFTVWFPWSLAGILFSITMTRMTRKIE
                     EMEQIEWDSY"
     gene            2130..2984
                     /gene="lgt"
                     /locus_tag="ACIZE5_002545"
     CDS             2130..2984
                     /gene="lgt"
                     /locus_tag="ACIZE5_002545"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HGC6109648.1"
                     /translation="MGFVLGVLNPHVVEIGSVVIHWYGVIIAAGILAALQLSTKEAKK
                     KGLEEDTIIDMALWAIPIGLLGARLYYVLFELGYYLQNPGQILAIWNGGIAIYGGLIA
                     GGGTLYWYAKKKGTSLALVLDILAPNVLLAQSIGRWGNFMNQEAHGGPVTRQFLENLY
                     LPEFIIEQMNMNGTYYHPTFLYESLWSLLGFVLIVTIRNRKQLLRQGEVALSYVLWYS
                     VGRFFIEGMRTDSLWIGEWIRVSQALSLALFIGAIVVWFIRRQDYPPISYYSDGNKGQ
                     KKTIKMVN"
     gene            3131..3364
                     /locus_tag="ACIZE5_002546"
     CDS             3131..3364
                     /locus_tag="ACIZE5_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HGC6109649.1"
                     /translation="MEKAILQLETLSCPSCMQKIEGAVKSVNGIDKDSIKVLFNSSKV
                     KTNFDSAVTSIEEIQKAIENVGYPVLKAKVKAV"
     gene            3562..5466
                     /locus_tag="ACIZE5_002547"
     CDS             3562..5466
                     /locus_tag="ACIZE5_002547"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGC6109650.1"
                     /translation="MQQYILSKKNVITVISGLLIVLGFFSHFVLENVGLSEWSLIIAS
                     VFGITPIAIQAFQAMKVKVISIDVLVSIAAIGALFIQNYEESAIVTFLFLFGHYLEQR
                     TLNQTRSAIKELTEMAPESALKQMDNGEFEEVEVDDIDEGDILLVKTGAKVPVDGIVL
                     TGEGHINEASITGEAIPVNKLADAEVFAGTILENGTIQIRADRVGEDTTFGKIIELVE
                     EAQDSKSEAERFIDRFSKYYTPAVLVLAIVVWAFSQNIELAITILVLGCPGALVIGVP
                     VSNVAGIGNGARNGVLLKGSEVIQDFSNVDTIVFDKTGTLTVGNPTVAATELYEKDPA
                     ETLGYLASVERESDHPLAKAVLNQIGETNFYPVEGTEVVKGGGIVSSVAGHRVAVGNV
                     ALMEKENVTLSKKVQKDVKRFEQQGNSLVLTAVDGELKVLMGIRDQVRPGVKANLQEL
                     KDLGVKNLVVLSGDNQGTVDVVAGELGLTEAHGYMLPEDKSAYIGKLQQRGQIVAFVG
                     DGVNDSPSLALADIGIAMGSGTDVAIETSDVVLMNSNFSNLPHALGLVKATANNMKQN
                     IVISIGVVLVLLTSVFFSEWMNMSIGMLVHEGSILVVIFNGMRLMKYKLKGRKEQKEV
                     SAPAEKVKIS"
     gene            5776..6138
                     /locus_tag="ACIZE5_002548"
     CDS             5776..6138
                     /locus_tag="ACIZE5_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HGC6109651.1"
                     /translation="MEKVCQVTIVHKEKVNVIKKKLDQKDFSNLLVLGKCFSDSSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVFLKLSENLSMKS"
     gene            6155..6766
                     /locus_tag="ACIZE5_002549"
     CDS             6155..6766
                     /locus_tag="ACIZE5_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HGC6109652.1"
                     /translation="MLQSIFSAIAVYISTSIDYLFILLIIFSQSHTKKGIRHIFWGQY
                     LGTGILVAVSLFAAYVLNFIPQDWIIGLLGLIPIFLGIRVAFVGEEEEEEEEVVEKLE
                     SRGTNRLFWTVALITIASGGDNLGIYIPYFTSLAFSEIIIALIVFAISVAVLCYISYK
                     LAKISFVSETLEKYERIIVPIMFIALGIFIMIENGTIQTLLGF"
     gene            complement(6868..7776)
                     /locus_tag="ACIZE5_002550"
     CDS             complement(6868..7776)
                     /locus_tag="ACIZE5_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HGC6109653.1"
                     /translation="MSKSDKDHNHSNQNQPKKNIKIAFFINLIFSISEFFFGFLFNSV
                     SIMSDAVHDLGDSISIGFAWFFQGYSEKKQDERFTFGYNRFSLLGALITGVVLISGSF
                     FMIYRSVPRLIDPQPVNYSGMFWLSLVAIALNGYAAWILSKGTSKNESMLNLHMLEDV
                     LGWIGVLIVSILMNFTEAYRLDPILSILIALYILYKTVPEFFTTMKILLNGSPENVNV
                     KSLADSIKNVPAVKDLSHFHIWSLDGEENALIITVLIDPSDIDKAREIKEEIAEVAHK
                     SSVENHITIEITTSKEELEKGYSHNT"
     gene            complement(7818..8132)
                     /locus_tag="ACIZE5_002551"
     CDS             complement(7818..8132)
                     /locus_tag="ACIZE5_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HGC6109654.1"
                     /translation="MDIKTTSPIDKGSILSISKLFKVISDPTRLSVLFLLQKKECSVG
                     NIAISLDMEQSAISHQLKTLKDARLVKSRREGKSMLYSLDDLHVFSILEQVLTHVNEL
                     EK"
     gene            8431..10362
                     /locus_tag="ACIZE5_002552"
     CDS             8431..10362
                     /locus_tag="ACIZE5_002552"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGC6109655.1"
                     /translation="METIQEQQSQEKHNHNHNHDHDHDHGKMPVVLYFVGLALAVIAL
                     FLNEDYQLVQNVLFSIATISAGYHVILLEGLGETIENSKAQKKFIPNSHILMGLAAIG
                     ASLMGNFWEGTLLILIFSGAHFLEDYAEGRSKREITKLLEMNPTTARLILPDGSTKNV
                     DVSELKVGDQLQVLNGDQVPIDGVILSGSTSIDESSITGESIPKEKSKGDGVFGSTIN
                     GTGTFTMKVTKENKDTVFSKILQLVNQNQDNQTKAASIIQKFEPKYVTVVLIAIPLFM
                     LLAPFLLDWTWSQSVYRGLVLLVAASPCALAAATVSATLSTTSNLAKKGVLSKGSSYL
                     SQLADIKAIAFDKTGTLTKGKPEVTNYYFADSVNEENMIDIVVALEKESNHPLADAIL
                     RKFEQKNKLTIEVENQIGKGLTGDYKGRNYRIGKPTSFDDVSDEYSRLNNEWASEGKT
                     VVYVAVDEEVIGLIALMDVPSEYAKETIEYFRKQGIHTTLITGDSEMTGKAVAKQLGI
                     DEVIANVMPEDKSRIIDEQKEKYGVTAMVGDGVNDAPALVNADVGIAMGDGTDVAVEV
                     SDLVLMQNNLSKLVQSHNISSKMNRVIWQNIIFSMAVVAFLIVVSFLGLTDIAISVII
                     HEGSTLVVILNGLRLLKAV"
     gene            10655..11206
                     /locus_tag="ACIZE5_002553"
     CDS             10655..11206
                     /locus_tag="ACIZE5_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6109656.1"
                     /translation="MGYNVQPLRSQQEINDFLFCLRRNKNAERDVFLFLIGINSGLRM
                     SDIVKLKKKDVITSKNPRIVEQKTGKTRILYLSSLQDLIHGYTAPLDPEAYLFPSTKG
                     GHLEVNTVYQMFQKVAKLLGRDDIGTHTLRKTFGYHYYKKTKDVATLMEIFGHSSEKI
                     TKRYIGINEDEISETLLNFRLGF"
     gene            11519..12061
                     /locus_tag="ACIZE5_002554"
     CDS             11519..12061
                     /locus_tag="ACIZE5_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBECR4 domain-containing protein"
                     /protein_id="HGC6109657.1"
                     /translation="MSIKETTQITRQLNAIYKAAHLLQEHFVDKKVSFVGEVSTVAII
                     FSTTNFMHLCGIDYRRGTHLFFQDALDRKINLQDIQIKTDGTTFQKLQVIGSLDLLLG
                     KHISIVGRGVYSSLRYDAAIRTRKKILALSLKQNGLIYIPISLLNLSSKEIGPGQKVT
                     GIFSEDLTSGELKMIMEVID"
BASE COUNT         4048 a         2093 c         2609 g         3744 t
ORIGIN      
        1 aatttaatag agaagcctgg cgtctattaa gaaataattt tcttgatgag cgtcaatttt
       61 tttaacggaa atctatccta tactaaattc agtaaagaaa aaggaggaat caaagaaagc
      121 tattttaaac aaaccaaaat tataggagga ataaatcatg actgaaaata aagctactca
      181 agaaagaaca ccccaagaaa gattgcaaga agaacaagaa cacaaggaac atgttcatca
      241 tacgaaaatt aatgcagcgg ccattgcgga tcatctttta ggcaacatgc atacattaca
      301 tgtgaaactg caccaatatc actggtatgt aaaaggagcc aatttcttta cgttgcatga
      361 aaaatttgaa gagttgtata acgaaaatga aaaatggttc gacaaacttg cggagcgtct
      421 aattacttct gggcataaac ctgcttcgac aacggttgaa tttgaaaaat attcgatgct
      481 ttcggaagat gcagttaata aatacgctaa agcagaagac atggttgaaa atattatcga
      541 ggacttcaga agcactcgtg acctaactat tcgcgcgatt cgtttagctc aagacgaggg
      601 tgacgatgct ttagaagata cattgattgc ttttaaaaat gacttagaca agaacatttg
      661 gatgctgcaa gcgttcattg gtaaagaagc attagaagat gatgacgctc ttgatgagga
      721 tgaagattaa ggtaaaagta gaagctgatt tagggattgg aattctttcc agtccttttt
      781 ccattttctt gatgtgcatc aatttttttg tagtaagaga cttatataat aaaagcagcg
      841 aatataaaca aaataaataa agggggagaa tgaattgact aaacataccc atcatgaaat
      901 tggcgaccac gcagcctgta tccgcttggt tccaatattc aatcacttag aggatagcgc
      961 gatgaattac attgctgaaa aagcccacac gaaacagtat caaaaaggag agtttctgtt
     1021 tcgttcacaa gaaaaagagg atactttata tattatcaat cgtgggaaaa tccgtattta
     1081 tcgattggca gactctggca aagagcagct agtgcggatc ttgaaccctg gtgatttcac
     1141 cggagaatgg accttgttca acccggatgc agtacacgag gaatatgccg aagcaacccg
     1201 agataccgtt gtctgtatga ttcagcaaaa agatgtccaa gattttctgg aacaataccc
     1261 agctatttct ttaaaactat tggcggaaat gtctaaacgg ttagaaagtt cagaacgtca
     1321 aacgacacaa gtagccgtgg agagtgtcat tacccgttta gttttgtttt tggcagaaaa
     1381 tgtggaacct gaaatgggca actctcccac catcaccctg ccgatggcaa aaaaggacat
     1441 tgcttcctat ttaggaacga cacctgagac catcagtcgc aaatttggag aattggagga
     1501 cgaaggattg attcaacagc tgtctgggaa aaggatcaag attcaggatt tagatgattt
     1561 attgctttac agcgaataat cggacacact tttttctaca cgttggtgtt ctgtcgctct
     1621 tcattaacaa cgggacagaa ctcagtgctt ttgcttccat ctgtccgttt ttggcttttt
     1681 taagacagaa cgaccttcat tcattggaaa aataaaagca caaacatgat aaccctcaag
     1741 tttttttgtt ttatttttct ttaagatagg gttgtcgaac aaaacgtaaa aataagtagg
     1801 gtgaatgtgc attgtttttg ggtgatagtt gccatcacgt tgtcagcagc gggggcattc
     1861 tttgtcgtcc ctttcaccaa gaacacgatt ggcggcgaag caaaaacgtc taacgttgtt
     1921 gaggcagata ggttagctat ggaaaaagaa gaggaagttg taaaaggagc cggcgtaatc
     1981 ggacacggaa aagtggcgta ttacgaagcg agtgaccagg gagataaaag tgtattcact
     2041 gtttggtttc catggagctt agccggaatc ttgttcagca tcaccatgac tagaatgacg
     2101 cgaaaaattg aagaaatgga gcaaatagaa tgggattcgt attaggcgtt ttgaatcccc
     2161 atgtggtgga gattggttct gttgtgattc attggtatgg agtcattatt gcagcgggca
     2221 tattagcggc tctccagttg agcaccaagg aagcaaagaa aaaaggactg gaagaggata
     2281 ccattatcga tatggcctta tgggcaattc cgattggact cctcggcgct cggctttatt
     2341 atgtgttatt tgaacttggt tattatctgc aaaatccagg acaaatcctt gcgatttgga
     2401 atggcggcat tgcgatttat gggggattga ttgcaggagg gggtacgcta tattggtatg
     2461 caaagaaaaa aggtacttct ttggcactcg ttcttgatat tttagcgccc aatgtattgt
     2521 tagcccagtc cattggtcgt tggggcaatt ttatgaatca ggaagctcat ggtgggccgg
     2581 ttactcgtca attcttggaa aatctttatt tacctgaatt tatcattgaa caaatgaata
     2641 tgaatggtac ctactaccat ccgacttttt tatacgagtc attgtggagt ttgttgggct
     2701 ttgtcctcat cgtcactata cggaaccgaa aacagctttt gcgtcaagga gaagtcgctt
     2761 tgagttacgt tttgtggtac tcagtgggtc ggttcttcat tgaaggtatg cgaacggaca
     2821 gtttatggat tggcgagtgg atccgcgttt cgcaagcctt gtctctggcc ctgtttattg
     2881 gcgcgattgt agtatggttt atacgcagac aagattatcc accaatttct tattattctg
     2941 atggcaataa ggggcagaaa aagactatta agatggtgaa ttgagcaaaa agataaaaag
     3001 aagtgcaaaa cttgatatgc gtcaattttc gtttgctaaa agtgagctat actacagttg
     3061 taaagaggaa aaggcagtgt tcattaatct gctgccgata aaataaaaac acataaagga
     3121 gataggaatt atggaaaaag ctatattgca attagaaacg ttgtcttgtc caagttgtat
     3181 gcaaaaaatt gaaggtgccg tgaaatcagt taacggtatt gataaagaca gcattaaagt
     3241 attattcaac tccagcaaag tcaaaaccaa ttttgattca gctgtcactt cgattgaaga
     3301 gattcaaaaa gctatcgaaa acgtaggcta tccggttctt aaagcaaaag tcaaggccgt
     3361 ttaacagatt aaatgaacta ggcaattctg gaagaaaagc tatttttcca ggattgcttt
     3421 ttttgttgca atccgattcg aggtgcttag aaacgataaa agagaacttt ctaaacttga
     3481 tgtcagtcaa ttaattactt aggcaattat cttatactgt gtttatcaat aaaagagaaa
     3541 ttaaatttgg agggaaaaag catgcaacaa tatatattaa gcaagaaaaa tgttatcacc
     3601 gtcatcagtg gattgttaat cgtactcggt ttcttcagtc actttgtttt agaaaacgta
     3661 ggactttcag agtggtcttt gatcatcgcc tctgtctttg ggattacgcc aattgccatt
     3721 caagcgtttc aagcaatgaa agtcaaagtc atcagtattg atgtcttagt cagtattgca
     3781 gcgattggtg cgctttttat tcaaaattat gaagaatcgg ctattgtcac gttcttattc
     3841 ttattcggac actacttgga acaacgaaca ttgaaccaaa cgcgatctgc tatcaaagaa
     3901 ttgactgaaa tggcacccga aagcgccttg aaacaaatgg ataatggcga atttgaagaa
     3961 gtagaagtgg atgatataga tgaaggggat atcttgctcg ttaaaacggg tgcgaaagtt
     4021 ccagtagatg gcatagtcct tacgggtgaa gggcatatca atgaagctag cattacaggt
     4081 gaagctattc cggtcaacaa gctagctgat gcagaagttt ttgcaggaac cattttagaa
     4141 aacggaacga ttcaaatcag agctgaccga gttggtgagg acaccacatt tggaaaaatt
     4201 attgaactcg tggaagaagc acaagattct aaatccgaag cggaacggtt cattgatcgc
     4261 ttttctaaat actacacacc agctgtcttg gttctggcaa ttgttgtatg ggcgttcagt
     4321 caaaatattg agttagcaat caccatcttg gttctaggtt gcccaggcgc attagttatc
     4381 ggagtgcctg tctcaaacgt tgccggtatt gggaatggtg ctcgtaacgg tgttctttta
     4441 aaagggagtg aagtcattca agacttcagt aatgtggata caattgtatt tgataagaca
     4501 ggtactttaa ctgtcggaaa cccaaccgtt gcagcgactg aactgtatga aaaagatcct
     4561 gctgaaacgc ttggctatct ggccagtgtg gaacgggaat cagatcatcc attagcaaaa
     4621 gcggtcttaa atcaaattgg agaaacaaac ttttatcctg ttgaaggaac tgaagttgtg
     4681 aaaggcggcg gaatcgtttc aagtgtagct ggacatagag tggctgttgg gaatgtggcc
     4741 ttgatggaaa aagaaaatgt cactctcagc aaaaaagtgc aaaaagatgt caaacggttt
     4801 gaacaacaag ggaactctct cgttttgaca gcggtcgacg gtgaattaaa agtactgatg
     4861 ggcattcgcg atcaagtccg tccgggtgtg aaagctaatt tgcaggaatt aaaagacttg
     4921 ggcgtgaaaa atctagtcgt tctttcagga gataaccaag gaaccgttga tgtggtcgcc
     4981 ggcgaacttg gtttgaccga agctcacggc tacatgttgc cggaagacaa atcggcttat
     5041 atcggaaaac ttcaacaacg tggtcaaatt gtagcctttg ttggagatgg cgttaacgat
     5101 agtccgtcct tagctttagc agacattgga atcgcaatgg gaagcggaac ggacgtagcg
     5161 attgaaacat ccgatgtcgt tttaatgaac tcgaacttca gcaacttgcc tcacgcatta
     5221 ggattagtaa aagccaccgc aaataatatg aaacaaaata tcgtgatttc aattggagta
     5281 gtgttggtct tgttgaccag cgtcttcttc agcgaatgga tgaatatgtc tatcggaatg
     5341 ttggttcatg aaggtagtat cttggtggta attttcaatg gcatgagatt aatgaagtat
     5401 aagttgaaag gtcgaaaaga acaaaaagaa gtatcagcac ctgcagagaa agtaaaaata
     5461 tcttaagaat aaattagaag aggctgagac aatagtccat ccttgaaatg acaaaagcgg
     5521 aaactcagat ttttaaatct gggattttcc gcttttttga gttcttgaaa aaaaataaga
     5581 gtatagagta tgttctttat aaaattaatt ttcgtgtaaa tgattaaaaa atttaataat
     5641 aaaatttaaa ttcctattaa gttgtaacac atgaaattgc ttataatagt gtattgaaat
     5701 taaggtagat tgacaaacga gtgatcaaat agatatacta ccttcaaacg accgtttgaa
     5761 tgtgaggtga gatgaatgga aaaagtttgc caagtgacta tcgtacataa agaaaaagta
     5821 aatgtaataa aaaaaaaatt ggatcaaaaa gatttttcaa acttacttgt gttagggaaa
     5881 tgtttcagcg attcttctag gattaaaatt ttctatgctt tagaaaccta taaggaaatg
     5941 tgtgtctgtg atttagcaga aatacttact gctagtgtcg ctacaacgtc acaccattta
     6001 cgttttttaa aaaaacatgg aatggcaaaa tcacgtcaag atggaaaagt agtttattat
     6061 tctttagcga atgaagacat cctttccgct attcgtgttt ttttaaagtt atcagaaaat
     6121 ctatctatga aatcttagtt tggaggaagt tattttgtta caaagtattt tttcagctat
     6181 cgctgtttat atttctacca gtattgatta tttgtttatc ttgctgatta tcttttctca
     6241 aagccacaca aaaaaaggta ttcgtcacat tttttggggt caatatcttg gaacaggtat
     6301 tttggtagcc gtaagtttgt ttgctgctta tgtgctaaat tttattccgc aagattggat
     6361 cattggtctt ctcggtctaa ttccgatttt cttaggaatc agagtcgctt ttgttggcga
     6421 agaggaggaa gaagaagagg aagtcgttga aaaactcgaa tctagaggaa ctaatcgctt
     6481 attctggaca gttgccttaa taacgattgc ttctggaggc gataatttag gtatttatat
     6541 tccatacttt acctcgttag ctttttcaga aatcattatt gctttaatcg tattcgctat
     6601 ctctgttgcg gttctctgct atatcagtta caaattagcc aagatttctt ttgtttccga
     6661 aacgttagaa aaatacgaac gaatcattgt ccctataatg tttattgcgt taggaatttt
     6721 tattatgata gagaacggga cgatacaaac gctactaggt ttttaaaaat cataatcacg
     6781 aaagataaaa agagaggcag cgactaatca aaatcgctgc cttttttgct tttcaaataa
     6841 tgaagtattt tttagcgtag aactatctta cgtgttgtgg gagtatccct tttcaagctc
     6901 ttctttgctt gtagttattt ctattgtgat atgattctct acgcttgatt tgtgtgcgac
     6961 ttctgcaatt tcttctttta tttccctagc cttgtctatg tctgaagggt ctataagaac
     7021 cgtgatgata agggcgtttt cttccccgtc cagtgaccaa atgtgaaaat gtgagaggtc
     7081 ttttacagca ggaacatttt taatggagtc cgccaagctc tttacgttta cattttcagg
     7141 cgaaccattc aataaaattt tcattgtggt gaaaaattca ggaacggttt tgtagaggat
     7201 ataaagtgca atcaaaatcg ataagatagg atccagacga tatgcctcgg taaagttcat
     7261 tagaatactc acaatcaaga ctccaatcca ccctaatacg tcttccagca tatggaggtt
     7321 caacatgctc tcgtttttgg atgtgccttt gcttaaaatc cacgcagcat atccattcaa
     7381 tgcaatagct acgagagaaa gccagaacat gccactataa tttacgggtt gtgggtcaat
     7441 caaacgtggc acactacgat agatcataaa aaacgagcca ctaattagca caacgccagt
     7501 tatcagcgcg cccagtaaag aaaagcggtt atagccaaaa gtgaaccgtt catcttgttt
     7561 tttctctgaa taaccttgaa aaaaccaagc gaatccaatt gaaatagagt cccctaaatc
     7621 atgaactgcg tcggacataa tggacacact attgaaaaga aagccaaaga aaaattcgct
     7681 tatagagaaa ataagattta tgaagaaagc aattttaata ttctttttcg gttgattctg
     7741 attcgagtga ttatggtctt tatctgattt tgacatttaa aaacctccta agtttgtatg
     7801 ctacatacta attggtttta tttttctaat tcattaacat gagttaagac ttgttcgaga
     7861 atactaaaaa catgaaggtc atctaaactg taaagcatac tttttccttc tcttcttgat
     7921 ttcactaagc gtgcgtcttt caacgttttt aattgatgag aaatagcgga ctgttccatg
     7981 tccagagaaa tagcgatatt tccaacacta cactcttttt tctgtaaaag aaagagaacc
     8041 gacaatcgtg taggatcact aatcacctta aatagtttgc ttattgacag aatagatcct
     8101 ttatcgattg gagaagttgt ttttatatcc atagtgtttt tattcctttc atatgacctt
     8161 ccgttcatat ctatattacc atatgagcga aacaatgcta atcttttgtt tataaaagag
     8221 aagtggcgtt ctctttatct tgacaaaatg tatatagcga tataaaatga gtatacaaac
     8281 atatgattaa ttagtcatat gtaaggtgga ttcattacga tttacttttg gaataaacga
     8341 aaggagtcag aaatagcaga aatttatgtg attcaagaag taaatgatgg aaaacaaagg
     8401 aattataaat tatataggga ggcaatagaa gtggaaacta tccaagaaca acagtctcaa
     8461 gaaaagcata atcataatca caaccacgat cacgaccatg atcatgggaa aatgccagtc
     8521 gttttgtact ttgttggttt agcattagca gtgattgctc tatttttgaa tgaagattat
     8581 cagttggtac aaaatgtttt gttctcaatc gctacaatca gtgccgggta tcacgttatt
     8641 cttcttgaag gccttggaga aacaattgag aattcaaaag cacaaaaaaa gttcatacct
     8701 aattctcata ttttaatggg attagcggca attggagctt ctttgatggg gaatttttgg
     8761 gaaggaacat tattgattct tattttttct ggcgcacatt ttttggaaga ttatgcagaa
     8821 ggaagaagca aacgagaaat aacgaaatta ctcgaaatga atccaacgac tgcccggtta
     8881 atcctgcctg atggtagtac aaaaaatgtg gatgtcagtg aattaaaagt gggagatcaa
     8941 cttcaagtgt tgaatggcga tcaagtacct attgatggcg tcattttgtc tggatctaca
     9001 tccattgatg agtcgtctat tactggagaa agtatcccga aagagaaatc caaaggagat
     9061 ggcgtcttcg ggagtacaat caatggaaca ggtaccttca cgatgaaagt caccaaagaa
     9121 aacaaagata cagtattttc aaaaatttta caattagtga atcagaacca agataaccaa
     9181 acaaaagctg cgagtattat ccaaaaattt gaaccgaaat atgtcacagt tgttttaatt
     9241 gccattcctc tattcatgtt attggctcct tttctacttg attggacatg gtcacaaagt
     9301 gtctatagag gattggtcct tttagttgca gcttcaccgt gtgctttagc agcagctact
     9361 gtctcggcaa cgctatcgac gacttctaat ttagccaaaa aaggagtcct ttcaaaaggt
     9421 agttcttacc tgtctcaatt agccgatatt aaagcaattg catttgataa gacgggcacc
     9481 ttgaccaaag gaaaacctga agtaaccaat tattattttg ctgattccgt gaacgaagaa
     9541 aacatgattg atatcgtagt agctcttgaa aaagaatcca atcacccctt agcagatgct
     9601 attctaagaa agtttgagca aaaaaacaaa ctaactattg aagtagaaaa ccaaattggt
     9661 aaaggattga cgggagatta caaagggaga aattatcgta taggaaaacc gacttcgttt
     9721 gatgatgttt cagatgaata tagtcgttta aataatgaat gggcgtcaga aggtaagaca
     9781 gtcgtatacg tagcagtaga tgaagaggtt ataggcctta ttgcccttat ggacgttccg
     9841 agtgaatatg ctaaagaaac cattgaatat tttaggaaac aaggtataca caccacatta
     9901 attactggtg actcagaaat gacgggaaaa gcggttgcta aacaattagg aatagatgaa
     9961 gtgattgcga atgtcatgcc ggaagacaaa tccagaatta tagacgaaca aaaagaaaaa
    10021 tacggcgtga ccgccatggt tggagacggt gtaaatgatg ctcctgctct tgttaatgca
    10081 gatgtgggaa tcgctatggg agatgggact gatgtggcag tagaggtatc tgatttagtt
    10141 ttaatgcaaa acaatttatc taaattggta caatctcata atatttcttc gaaaatgaac
    10201 cgtgttattt ggcagaatat tattttttca atggccgttg ttgctttttt aattgtcgtt
    10261 agtttcttag gcttaacgga tattgcaatc agtgtcatta ttcatgaagg aagtactttg
    10321 gttgttattt tgaatggact tcgattgcta aaggcagtct aaagaatgat tgcacaactt
    10381 caaattaatc gagtaataga gataattaag gattacacta cattttttat ctctattact
    10441 tgtttatatt tatctagatg ttcaaagtca aaatgatata tcaaccatac tcttgtggcg
    10501 cgggttgaat ataagataca tgaaattgga taaaatcatg tatcaagaat cctatcctta
    10561 tagggttctt tttttttact ccccctaaac acacgatttc gtgttgtaat aactataatc
    10621 atgtattcga acagactaaa aaggagggat tgtcatgggc tataatgttc agccactacg
    10681 gtcgcaacag gagattaatg attttttatt ttgcctgcga cggaataaaa atgcggaacg
    10741 tgacgttttc ttgtttctaa ttggaattaa cagcggtctg cgcatgtccg acatcgttaa
    10801 actcaagaaa aaagacgtga ttacctcaaa aaacccgcgc atcgtggagc aaaagacagg
    10861 gaaaacacgc attttatact taagcagctt acaggacttg attcacggct ataccgcacc
    10921 cttagatccg gaggcttact tgtttcccag tactaagggc ggccatttag aagtcaatac
    10981 ggtctaccag atgtttcaaa aggtcgcgaa gctgttagga agggacgata tcggcaccca
    11041 caccctacga aaaacctttg gttaccacta ttacaagaaa accaaagacg tggccacctt
    11101 aatggaaatc tttggtcaca gcagcgagaa gattaccaaa cgctacatcg gaattaatga
    11161 agatgaaatc agtgaaacgt tattaaattt tcggttaggt ttttgattgt attatataat
    11221 agataagcac agtaagacgg ttataatcac ccacagtatt ggacaaatca accttttttt
    11281 ggtatattat atatacaaat gagagcaggc tcatagtcaa cttgatataa atccggaaca
    11341 taagggtccg gcgggtggcg agcaccaaaa ctaaactcga tacaaatccg gaacgtaagg
    11401 gtccggcggg tggcaagcac caaaactaaa cctgtacaaa aggctgctct tttgagcagc
    11461 tttttttatt gggaaaaagg agcattcttc gcacgcggca aaaaaagaat acaaacgcat
    11521 gtctataaaa gagacaaccc aaattaccag acagttaaac gcgatttata aggctgctca
    11581 tctcttacaa gaacattttg tagataaaaa agtatccttt gtcggagaag tctcaacggt
    11641 agcgattatt ttttcgacaa ctaattttat gcacctctgt ggcattgatt atcgcagagg
    11701 cacacacttg ttttttcaag atgccttaga caggaaaata aatttacagg atattcaaat
    11761 caaaacggat gggacgacct ttcagaaatt acaagtaata ggtagccttg atttattatt
    11821 ggggaagcat atttctattg ttggcagagg tgtttactct tctcttcgct atgatgcagc
    11881 tattcgaaca aggaaaaaaa tattggctct gtctttgaaa caaaacggat taatctatat
    11941 ccctatctct ttgttaaacc tatcatcaaa ggaaattgga cctggacaaa aagttactgg
    12001 catttttagc gaggatttaa catccgggga acttaaaatg attatggaag tcatcgatta
    12061 atcattaata gtgatatgcg acgtcatttt gaagtaatta ttctattttg ggttataaaa
    12121 taaagcattt taagacgatt tcaaatcatt catgtgggtt atttatcacg gatgagcttg
    12181 aaatcgtctt ttatacgtat caaattgaaa tgttcggcat acaacctatc gttgttacta
    12241 cattactaat tgtcacttgt taaggaactt ggatcctttc taaacattcc ctagagataa
    12301 attttacttt atccctccgt taatatccaa tttaagcacc tttccgattc agggttaatt
    12361 tgcatatcaa gtgcagcttg tgttctagta agattagccc ttttagtccg gctgagttga
    12421 cttatggata taagatatgg tcatagcaaa tagatactac gtatagtctg ttaatttagt
    12481 gtcattaatc ttaa
//
LOCUS       DBBGSZ010000064        12144 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.067, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000064 DBBGSZ010000000
VERSION     DBBGSZ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12144
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.067"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..566
                     /locus_tag="ACIZE5_002555"
     CDS             <1..566
                     /locus_tag="ACIZE5_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGC6109658.1"
                     /translation="YFKSEKDTSSLTLTLEEGVEPDKVTSKVINQLKEKGSLKHLGEY
                     EVLDTAMLTKGIGQILSTITYFITAVAGISLFIAGVGVMNMMYISVSERTKEIGIRRA
                     LGATRKSIMLQFLLEGLILTLSGGLIGYLLGMALAYSVGSLIKVNVSLDLFTILLAVG
                     VSSVIGLVFSVMPASEAAKKDLIDILR"
     gene            967..1572
                     /gene="fic"
                     /locus_tag="ACIZE5_002556"
     CDS             967..1572
                     /gene="fic"
                     /locus_tag="ACIZE5_002556"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0070733 - AMPylase activity [Evidence
                     IEA];
                     GO_process: GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="HGC6109659.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            1588..2160
                     /locus_tag="ACIZE5_002557"
     CDS             1588..2160
                     /locus_tag="ACIZE5_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6109660.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2412..2669)
                     /locus_tag="ACIZE5_002558"
     CDS             complement(2412..2669)
                     /locus_tag="ACIZE5_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109661.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(2795..3610)
                     /locus_tag="ACIZE5_002559"
     CDS             complement(2795..3610)
                     /locus_tag="ACIZE5_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6109662.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            4127..5452
                     /locus_tag="ACIZE5_002560"
     CDS             4127..5452
                     /locus_tag="ACIZE5_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HGC6109663.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            5445..5795
                     /locus_tag="ACIZE5_002561"
     CDS             5445..5795
                     /locus_tag="ACIZE5_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109664.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            5777..5962
                     /locus_tag="ACIZE5_002562"
     CDS             5777..5962
                     /locus_tag="ACIZE5_002562"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109665.1"
                     /translation="MGSIRMNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSF
                     YVEAAAGYHKYEYYIGY"
     gene            complement(6866..7141)
                     /gene="prgO"
                     /locus_tag="ACIZE5_002563"
     CDS             complement(6866..7141)
                     /gene="prgO"
                     /locus_tag="ACIZE5_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="HGC6109666.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(7113..8066)
                     /locus_tag="ACIZE5_002564"
     CDS             complement(7113..8066)
                     /locus_tag="ACIZE5_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC6109667.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            8678..10171
                     /locus_tag="ACIZE5_002565"
     CDS             8678..10171
                     /locus_tag="ACIZE5_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HGC6109668.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            10306..10602
                     /locus_tag="ACIZE5_002566"
     CDS             10306..10602
                     /locus_tag="ACIZE5_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HGC6109669.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            10703..11554
                     /locus_tag="ACIZE5_002567"
     CDS             10703..11554
                     /locus_tag="ACIZE5_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109670.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            11575..11787
                     /locus_tag="ACIZE5_002568"
     CDS             11575..11787
                     /locus_tag="ACIZE5_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109671.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIE
                     YRTEYLELTNQTDFLLIRKQQEQEKN"
BASE COUNT         4171 a         1864 c         2268 g         3841 t
ORIGIN      
        1 attattttaa gtctgaaaag gatacatcgt ctctaacgtt aactttagag gaaggagttg
       61 aacctgacaa ggtgacctct aaagtgataa accaattgaa agaaaaaggt agtttgaaac
      121 atttggggga atatgaagtg ttagatacgg ctatgttaac gaaaggaatt ggtcaaatcc
      181 tcagtacgat cacttatttt ataacagctg tagcaggtat atctttattt atcgcagggg
      241 taggtgtaat gaacatgatg tatatatctg tatctgaacg aacaaaagag atcggtataa
      301 gaagagccct aggagctact cgaaaatcga ttatgctgca gttcctttta gaaggtttga
      361 ttttaactct ttcaggaggg ttaattggct atttattagg aatggctctt gcttatagtg
      421 ttggttcttt gataaaggta aacgtgtcac ttgatctatt tactatttta ctagcggttg
      481 gggtatcttc ggttattgga ctggtctttt ctgtaatgcc cgcttcagag gctgcaaaaa
      541 aagatttaat tgatattctt agataaaatc agaatgacaa gaatatttac gttctagatt
      601 ctaaaataaa acacaaagag accaaccagg caccctattg tttctttgta gtatagagat
      661 attctttggc ttgtaagaga tcaatagagt taggtgaccg gagttcgaaa taaaggaaat
      721 ttttgattgt ataggagaat tctttatccc taatatttag aattttgagt atgccatgtt
      781 gatgttttag attctctata aatatagagg tgtatcaaag gtcaactaga ctgtgcaaaa
      841 tagagacact tgaaaaatct atcgggggtc agaaacttaa tagtttttga cacataaaca
      901 aaatcgcgat ataatggggt tgagagtgtt tcataaactt atgtcataaa gttaaggaga
      961 tttcgcatga ttttagagaa taaattggga ttaaccaatc aagttgagtt ggctaaggtt
     1021 gaagaaaaac tcagtaaaca aaaagcgaaa gaattgtacg attgtggaaa aataaatgaa
     1081 atcgaagttg gtacatttaa aggtttatct gaaattcatg aatttctatt ttcggatatt
     1141 tacgattttg ccggaaaaat ccgatcggtc aatattgcaa aaggaaattt tcgatttgca
     1201 ccagttatgt atttagaaca ttcgttacag catattgatc agatgccaca aacttctttt
     1261 gaagagatta tcaagaaata tgtggagatg aatatcgctc acccatttcg agaaggaaat
     1321 ggccgaagta ctagaatttg gctggatctc attttaaagg aagaattgca aaaagttgta
     1381 gattggaact taatcgataa agcagactat ctttctgcaa tggagcgaag tcccataaac
     1441 gatttggaaa tacgctatct aatttccaat gctctgactg ataaaattga cgatcgcgag
     1501 ttatatatga aaggaatcga tgtcagctat ttctatgaag ggtattctga gtatacgata
     1561 gatgatttgt aaaagtaggt ggaccaaatg acgaaatatg gatatgcacg tgtctcaacc
     1621 gcttctcaaa gtacaaaaga acaaattcaa cagttgcttg agaacggcgt agagaagaag
     1681 aatatttttt cagaaaaatt tacgggtaca aaacgggatc ggccaaaatt caatcagctg
     1741 ttggctggtc tgaagcctgg agatgaaata gttgttacga agcttgatcg atttgctcgt
     1801 aacacgagag aagcattaga gatcattgaa cctttactcg atgataacgt aacgatcaag
     1861 gttttgaatc taggaacgat tgaaaatacg tccatggggc gaatggtgac acggacgttg
     1921 ttgagtgtag cagaaatgga acgtgatatg attgtggaac gtacccaaga aggaaaaatg
     1981 tttgcaagaa agaataatcc taatttcaga gaaggacgtc cgaaagcaac aatcacaccg
     2041 aagaagaggc acgcatatga actgcttact tcaggtaaat cgtataagga agttgaagct
     2101 ataaccggtt tcagtcgcag tacgcttttt agaataaaga agaaaattga agaaagttaa
     2161 aaaagaagtc tcagcgaacc agacaggtaa atacttaatg cgttctagat atgagtctat
     2221 tagcatgttg tgaaatataa tattttttta tttacttgat ttctgctcaa aaaatgtgta
     2281 tggtaactgt aaaaggtaaa gtaattaaag gtatgctagc cacgcttact atattaggat
     2341 accatcatat atttataatg aacgatttgt tcgtctacca aacaacacat atcgttcagc
     2401 gtaagtcacg tttaggaacg tggctttttt agtgttatta tcgataaata atctattgac
     2461 tctattgatt ttatctccat atccctacgg tgttgattgt ctttagatct ttcatttaag
     2521 aaccaaataa ctatcataaa aatcagcact gctgctaata taataaacag cattcctatt
     2581 gtgatattac ctattgattt taccataact acgattaaag taataatggc attcaagtct
     2641 cctttgttct ctatatataa attagccata aatcatcttc ctttcaaatt aagatacttg
     2701 tttgatacca ataaatagta agcgtggcta gcataccttt ttctgtaata gcaagtgttc
     2761 taatagtcca aacttaatga tggaccgatg ctagttatag tacagtaatg ttttctttct
     2821 tatctagatt tttagtaagc tctatcagca aatctaacaa atctgagtcc ttttcagaaa
     2881 ctaaattaaa tctagtgttt acaacaaagt tttcatgttc tatattgttt agattatttg
     2941 cggaaaggag ggcttctaga tcttgacatt caaatctata tgcatcgtca taaatcttac
     3001 tagaaggagt gcttaattcg aaattactta ttttctcatc ttggaccaag ataaatttat
     3061 agatagtatc tttttgtgtt tttcttttaa aaacacaaca gagtgtgtta taaggaacgt
     3121 tataattttc atcagcctca ttttttctcc attcaaacaa atgataaact gcaaccaagt
     3181 tgccatcaat ttcatggaca gtgctctcgg taacatcctt taaagaacta tcaagggcta
     3241 atttatagta actagagaga ggaagtaaaa ttgtcgattt actgagatgg ttatcgtcta
     3301 tacgtgcaat catacctaaa tcaactaagg ttttattcca ggtgtttata gttttagttg
     3361 tcactcctag agactctgct atggtattga ccgaatgcca ggaatccccg ccttcattct
     3421 ttgccttaaa acagtaatac agatataaat taatagcttt gttattcggt aaatattttt
     3481 caagttctgt tggtagaata aagtaagaat ccttaatgtt ttttctgaac tgtctccagt
     3541 ctctgtagtt ttgtttataa agttgtgaaa cggtttttcc acctttagaa agtcctgcta
     3601 tcttaaccaa tcttattgct cctttcttga atctgtcatg atcatacagt attttttact
     3661 tgtagtccag caccttaata tattatccta tgtaattaat ttcgtactag atagtaatta
     3721 ttttttattt aattctctag tcacttacaa ataagttata taaactacga ttaataaatt
     3781 attacaaaaa ctattaagaa aacttctaca tacaactatt acaaaactat taagaaactg
     3841 aatactccta ttttttgttt ttaaggaaag ttttttcttt tttgaatttc ttattttttt
     3901 ctaatataac taagcaaaac tggataatac gacacttatt ttcaaatttt cacaagacta
     3961 atagtaaata tccatttaat aaagtgatac aatgtgttga ttttacaaat caacagaaga
     4021 agtagggaaa taacttacct atgcttcttt ttttgtacat ttaatcgatt cttctttaca
     4081 aaaacgaacg tatgtttgta taatgtggaa gaatggagtg ttatttatga tggattattc
     4141 aaaagagcca gtaaatgatt actttttgat cgatatgaaa agcttttacg caagtgtcga
     4201 atgtatagaa aggaatttag atccattaac gactgaatta gtcgtcatga gtcgagcgga
     4261 taatacagga tcagggttga ttttagcttc ttcaccagct gcaaagaaga agtacggtat
     4321 ttctaatgtc agtcgaccac gagatctacc gcaacctttt cctaaaacgt tacatgtcgt
     4381 tccaccacgc atgaatctct atattaagcg aaatatgcag gtaaacaata ttttcagaag
     4441 gtatgtagca gacgaagatt tattgattta ctcgatcgat gaatcgatct taaaagtgac
     4501 cagatcaatg aatcttttta cgactgaagg aacaagaagt caacggagaa agaagctggc
     4561 tcaaatgatc caggagaata ttaaagaaga gctaggattg cttgctacag taggtgtcgg
     4621 agataatccc ttattagcta aacttgcttt agacaatgaa gcaaaacata atgatggatt
     4681 ccttgctgaa tggacgtatc aaaatgttcc tgataaagta tggaatattc ctgaaatgac
     4741 agacctttgg ggtattggat ctcgaatgaa aaaaagactc aaccaaattg gtatcatgag
     4801 tattaaagac ttagctaatt ggaatccata cactattaag agccatttag gtgtgattgg
     4861 cttacagctg tattttcatg cgaacgggat cgatcgaaca gatatagcga tcccaccaga
     4921 accgacaaag gaaaaatcat atggtaattc acaagtgtta ccacgagatt ataccaggag
     4981 aaatgaaatc gaactggtgg taaaagaaat ggcggaacaa gtagctattc gtatcaggca
     5041 acataactgt aaaacaggtt gtgtccattt atacattggc acgtcgatct tagaaacgag
     5101 accaggtttt tcacaccaga tgaagatccc tataacagat aatacaaagg aattgcagaa
     5161 ttactgtctt ttcttgtttg ataagtatta tgaaggacaa gaagtaaggc acgttggaat
     5221 aacctatagc aagcttgtgt acactgattc gcttcagctg gatttattta gtgatccaca
     5281 aaagcaaatt gacgaagaaa atttagataa aattattgac aagattcggc aaaaatatgg
     5341 ttttacgtcg attgtacatg cttcttctat gttagaaggc gctcgtagta ttactagaag
     5401 tacattggtt ggtggccatg caggcggcgc aggagggctt aaaaatgatt gattataatg
     5461 atcgtggacg tttaaagtgg gcaggttttt atttatctga tcatactgaa aaaattgatg
     5521 ccgacaatga acaacgagcc aatcaaaatt tggcaaaaga acaaatgacg actgaagagg
     5581 ttgcggaagt attgaacgct gcagtcataa aaaatagatc agtatgtatt caaaaagaag
     5641 aacgaaacgc tgaaggatac tatccagaag atattgttag caagatctta ggtagtgatg
     5701 agctggggat ctacgttgga aaaaacaaag ttcactacga cgaaatacgt catatcgaat
     5761 tttaccagga taataaatgg ggtcgattag aatgaacatt atccagcaat atgagctaaa
     5821 gtatataacc tttgatcagc tatcagaaga gatttggggt tatggccagc gtttgataaa
     5881 tgaggttggt gttgaacgct tctctttcta tgtagaagct gcagcaggat accataaata
     5941 cgaatactat attggctatt aaagtgcaat aaaattatat ttcttttatg ttttacattt
     6001 tgtatcaatt ctgataaaat tacctatagg taattaaaaa atataaaaaa actagttaca
     6061 accttaggac gttgtaacta gcttgaagca tactagagct aactaaaata gcactagaaa
     6121 gcaatgttaa acccgtccaa caaacttgat ttaacattga gaccagctta ttcagctaaa
     6181 tatagttgaa taagcttctt ttgttttaaa aaaacaaaag gtgtactacg aataacgcaa
     6241 gtaaaagaaa tactattaca accagtaggc tacaagtaag tattactaaa cattgcgtag
     6301 ttagaacctt tgctctattg tctaaagcca caaaattaga gatcagcttt atgatgctaa
     6361 gagcgagctg catccatgcg gacataggtt cttttgacac tattaattct cctttttagg
     6421 ataagggaaa ttgctagtag ttttttcatt agcaccatcc cccttcattt gattgagtct
     6481 agtgctgctg tgatagtttg ctgtttaata tgcttacatt cttattataa cataaatgaa
     6541 acaaacacat ggttagaggt cgtatcaatc aaaatagtgt ctcacaaacg atttattact
     6601 tactcctgct gactaacgga ctgttcttca gtaactgtaa ctatatgttt gttaaaacca
     6661 ccattacctg tagataaaaa ccaatatatt tactatactc actatattaa atatatttag
     6721 tatagtaaaa actagaaaca ataaaatttg tgaatgttgt atacccccaa acaatacaca
     6781 tattttgaag gattaggatt aataaagcta aaaatatagt aagtatacta aatatattta
     6841 ctatatctag tatacttact atattttaat cttttgatcg tctattatat ataatccgtt
     6901 cctcgtcgtt taaagtatca acataggcgt ccattgcaag tttgactatt tcatacatag
     6961 gaatatcttt tgcataacta agatcccgaa tggtttttag tacgggagga tctacttgaa
     7021 ctggttttct ttctttcgca gtgtactttc gttcccctaa ctcgacatta atatcatctt
     7081 taattgaaat atcttcagca ccaattttct tcttatcttt gttcgttggt aataatgcca
     7141 tttagtttaa tctcctttcc aagaggtagg atatgattgg ccattgagtc agcatattta
     7201 ggtgtataat caaatccttc aatatcacca tgttgttcat agtattcaat tctttcttct
     7261 aattctgtaa agatgtctgc aaaaatagcc caccatcttc gatctacata atcatttaat
     7321 tggataccat tctcaccata catttctaac cgatccgagc ctttaacaat gcttttaaaa
     7381 atgtttgatt caccatactt atcaattgtt ttttgatagt ttgcgtgttg agaggaacgt
     7441 cgcactgaga aaagaacagg caaaattcca atgatttgaa gatgagactc ttcaaaattc
     7501 gtgacaatcg gaactaaaac tttattaata aaatcttctg ttccttccat tgcgtaccgt
     7561 tttaattctt gcattgcaat aatataatct gcagcagtta agaatgcacg aaccacatta
     7621 tctgttgatg gtgggcagtc gataaagata taatcgaaat tttttctcaa ttcttctaaa
     7681 ggtttaatga aggccaatga tctcttacga cgatcaggat atttttcgga caagtattca
     7741 ttaagttctt cagatccagg agagccagcc ataatatata aatgtggact tacttgagta
     7801 atacctgaaa cccagtcccc ttttttgatt gctgcagaca tggatcgatc aaagctagta
     7861 atttgatacg ttgatccaat gttggaagta gtatttcttt gttggtcata atcaattagc
     7921 aacacgtctt tttcaaaaag ttgactagaa acaatcgcta ataaatcatt gtctgtagtc
     7981 ttaccaatgc cgccttttct acctgtaagc attacaactt ttcctagttt atctgatgtt
     8041 ttaaatgcag tccgtaagtt ttccatagtt ccctccaatt tcctatacta aatatattta
     8101 gtatacttca tatacttaat atattcgata tatctaatat actccaaatt gataagaatt
     8161 cagactttat aaggaatata gtggatatac taaatatatt tgctatattc agtatatcag
     8221 atatattcaa aatgtcaaaa tatatttgtg cgttttgcgt tgacaattta gagtgaaaag
     8281 aggtaaactt aattctatag aaaccacaga taattcacta tttacaaagt agcaaaagca
     8341 gtggtactct ttaaacagaa aaattacata aaaaaaagag acggaaataa ttgattttag
     8401 cagaatcaat tatttctgaa tcacatggtt aggacatgtg ttcacgctcg tctcaagaat
     8461 atgtaagtag ctaccaacta cttatattaa aagttgatcg gatacctttt ccgattgcct
     8521 ttattctacc aaaaaaaggc gagcaactca acagaagaac gtttatttag tgtacttaaa
     8581 ttaaatattc ttaaacactg aagagagaac acatactatg gctgagatta aagctaaact
     8641 gtgttctctt tttgtttgag aaaggacgtt acaatcgatg ttgagcgaaa tttattcagc
     8701 tattcttaaa aacggcttac gtacatacaa atatcgaaac agcaccatga aacctgcagg
     8761 tcatattgat tccagtagga gtggtgctat ctttgcgtac cgtagcaagc aattaatgaa
     8821 tgttgggcgt ggtatggtca ttacttcgga agaagctatt ttagagaacg aaaagaaact
     8881 aacgcattgg acacctaata cctatcgctt tggtacttat gcggatgatt atcgaacagt
     8941 ggttaaaggt cattctgaga aaaacttaag tcaaatcaac acatttgtag ttgatatcga
     9001 ttcaaaagag aaccatcaag gcgaaattat tttagcctgt ttagatcaag tgggctacat
     9061 gccaacgcta attttagaat cagatcatgg ttatcaagtt tattttgtac taaagacacc
     9121 aggctatgtc acaaagaaaa gcaatttcaa ggtgatcgat gtagcaaaaa aaatttcaaa
     9181 aacaattcgt ctacagttgg ctgaaaaatt gtccggagtg gatctaggat gtaaccactt
     9241 cggaattgct cgattcccac aagaaaataa tattgttttt aaagaaatga actatcagta
     9301 ttcttttgct gactggattc aatggtcgat gaagcttgaa tcagatcaaa aaacaaaaga
     9361 agatcgagaa cgaaaactaa ttgtctttcc tgagaaaaaa gaaattcgtc aagtagatga
     9421 accgtggttc gatatgttac ttcataaagc aaacatcgtc ggcggagaag gacgtcttgg
     9481 tcgaaataat gtgattttca cgctttcttt agcttattac tcttcaggtt atgcattgga
     9541 tacttgcgaa tacaatatgt tcacattcaa cgaacggtta caggaaccgc tatctgaagc
     9601 agaattagta aagattgtac gtagtgctta ttctggtaat tatcaagcag caagcagaga
     9661 attcattatt gaattgtgcc agcaatgggt ttcaccaacc ttaaaaaata atgatctgtt
     9721 cattcaacga cgtggctggt ggaaatttaa aaagccacga gatcaaagaa aatatagtca
     9781 taaaaatgaa tggaaagaag atctattggc ttatctaagc gaaaaaagtc ttgctagtga
     9841 gccttatttg aacctgtcaa aaaaagaatt ggcttcacaa ctaacgatgc ccaagcgaac
     9901 acttgataag atcttaaatg agttacgaga ggagaataaa gtcttctaca aggtaacacg
     9961 aggaagaaat ggcggaatga tcattgcttc agtcaaaacg ttgttcgcga gggttattca
    10021 actaagtaaa gaaaagagac tagattattc aacaaggatc acagaggtat ttggactcaa
    10081 cgagagctta gtagaagaga catttagaca attatcaacc cccttgaacc ctcttaaaga
    10141 agtgaatctt tttgaagtag atacaggttg aaaaataaaa ggtgcaaatt gccttataca
    10201 atatatctat gatacttctg taggtgttgc tccctttgcc tagctacgtg taggtggtat
    10261 acttataact gcgtatgcag tcttatgtat catggaggaa gttgtatgtc gttaaaaaat
    10321 tatgtctatt cacatcctgt taatgtgttt atcattggtc gtttgggatt atctgtggaa
    10381 gtgttctgtg agctttatgg ttttaagcag gggactttgt cttcttgggt taccagggaa
    10441 aaaacagttg cttctttgcc gattgagttt cttcatgggt tgtccttagc ttctggggag
    10501 actatggatc aggtatatga ttgtttgtgt gtgttagagc aggagtatat tgagtataaa
    10561 atagctaacg agttaagaaa aaggaagaag tatatccagt agtagttttt atttacttaa
    10621 aaaattggtt cattgagcaa cctatcgctg ctaaagtagc aaaggaaaac gttaaaggaa
    10681 agaatttagg gaagaaatcg aaatgaaatc ggacgactgg attgaacaca cctggcttcc
    10741 tctgaaaaga aatagcaaac gaaagaaatt ttgggtattg caattatggc cattaggaaa
    10801 actttgtagt tacggggcac gacttattct tgatttaacc gtttactcga ttggagtatt
    10861 tggaacggct tattacttga taaatgatcc caataggatt gcagcatcag acatttttac
    10921 agtgctaatg acgttgattt ttgtcatgct attgtctatt tttactcaat tagtcatgca
    10981 atttaccagg caaaaattaa cagcaggaaa acttttcaaa agcctattcg atttaattgt
    11041 tgtaaatgca attctagcga ctttaataaa acaaattgaa caatctggaa gaacaacaaa
    11101 aggagtgaag gattttttat tgacgtttat tcactttgta aatggacaca tgtatttgtt
    11161 tgaagtgggt attattctct tttttgtcgg gtatgtatcc acgaaactta ttaaacgttc
    11221 aattgaaaaa gaaattgaaa ttgacctgat tccgacactt cttggttatg agtacaatgt
    11281 tgattttgga agatatgacg aattgatcaa tacggatatc gttcacacga gtatccatga
    11341 atctactgtt aagggcatca gatctatttt aaaaaatggc caggaaatga aagcaataga
    11401 tcgaagaaaa gagatctaca atttttatga agtcgaagca agcctacgat atggcatcgg
    11461 aaaattgtgg ttagatggaa gtaatattcg tcaaaacaaa ccatacattt tttggaacag
    11521 tagtgattta gaacttccaa tgaaagataa ataattatgg agaatcgttt gaaaatgatt
    11581 cctctataca ggattgtgct tatagttggc atggagttaa aaaccttaaa gaaggagcag
    11641 ttattcaaag tgaaagaacg tcataatcag ttactatgta gtaaaacggg tacgatgaac
    11701 attgaatacc gaacagaata tttagaatta acgaatcaaa ctgatttttt gttgattcga
    11761 aagcaacaag agcaagaaaa aaattaatgg ctacttatag ccaattgatt gatgaatggg
    11821 aacaattcaa ggaatctaaa attccagaac gtctctaaaa gcctttattt gtaaagagca
    11881 taaggaaacg tgggaacact ttttaaaaaa agtgttccaa taggctgtgc ctattacgtt
    11941 tctcaaaaat aaatgtggga acaaaatatt taaaaatagg atagtgaaag gatagtgaag
    12001 gatagtaaaa ggagggtagt aggatagcaa aaaggatagg ctccttttcg ctatcctttt
    12061 taaattggag gaattaatat ggaagtaaga ataagaaatg tggatgagaa aatcgtaaga
    12121 gaaattgatc gaagatgtga cgaa
//
LOCUS       DBBGSZ010000065        11017 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.068, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000065 DBBGSZ010000000
VERSION     DBBGSZ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.068"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(39..1415)
                     /locus_tag="ACIZE5_002569"
     CDS             complement(39..1415)
                     /locus_tag="ACIZE5_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HGC6109672.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(1543..2631)
                     /locus_tag="ACIZE5_002570"
     CDS             complement(1543..2631)
                     /locus_tag="ACIZE5_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGC6109673.1"
                     /translation="MFWSLELLIIAALIMISSEINFIFEPIGTFFSTLFAPVLIAGFL
                     YYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQISSLASNMPDF
                     IKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSLGSIVGTIASA
                     TVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTLANYISGQAIE
                     CLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLVTVFNDPVKAL
                     LCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLGIFLGVPFYAI
                     CKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            2803..3237
                     /locus_tag="ACIZE5_002571"
     CDS             2803..3237
                     /locus_tag="ACIZE5_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6109674.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(3315..3848)
                     /locus_tag="ACIZE5_002572"
     CDS             complement(3315..3848)
                     /locus_tag="ACIZE5_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HGC6109675.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(3942..5120)
                     /gene="mutY"
                     /locus_tag="ACIZE5_002573"
     CDS             complement(3942..5120)
                     /gene="mutY"
                     /locus_tag="ACIZE5_002573"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HGC6109676.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(5113..5910)
                     /gene="recX"
                     /locus_tag="ACIZE5_002574"
     CDS             complement(5113..5910)
                     /gene="recX"
                     /locus_tag="ACIZE5_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HGC6109677.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            6017..7399
                     /gene="rlmD"
                     /locus_tag="ACIZE5_002575"
     CDS             6017..7399
                     /gene="rlmD"
                     /locus_tag="ACIZE5_002575"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGC6109678.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(7573..8151)
                     /locus_tag="ACIZE5_002576"
     CDS             complement(7573..8151)
                     /locus_tag="ACIZE5_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HGC6109679.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            8473..8943
                     /locus_tag="ACIZE5_002577"
     CDS             8473..8943
                     /locus_tag="ACIZE5_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HGC6109680.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(9051..10277)
                     /locus_tag="ACIZE5_002578"
     CDS             complement(9051..10277)
                     /locus_tag="ACIZE5_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGC6109681.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
BASE COUNT         3296 a         2198 c         1845 g         3678 t
ORIGIN      
        1 ttattcaagc aacacgtctt tcataaccaa gtttccaatt atcttcttgg ctcgtcatct
       61 tcgaattctt ttctgaagta tcttcgttct tcttcaggtt ccgcttctgt ttcttccgga
      121 tcatgaaaaa tgacacggat tttaaggatt cgagaacctt ccatttcttc agaaaccagc
      181 gtaatattat cgacatcaaa cgataacttt tcgccttcat ccggaatcat gcctaatgct
      241 gtaatcaaat aaccagccat cgtatctaca tcactcatat gcagatcact gtcaaaagct
      301 tcattgaact catcaatcag catacgtcct tggatgatat attcgtgttc atcgattttt
      361 tcataaagat tctcaacttc atctgattca tcatcgattt ctccgacgat ttcttctaaa
      421 aggtcttcta gtgttgctaa cccaacgacg ccgccatatt catctaataa aatagccatc
      481 tgattctgcg tctttttcat ttcatataac agatcatcaa taaagaccgt ttcaggaacg
      541 aataaaggct cctgcatgat tttcttgata tctaaattat caaagccgaa tttatgggca
      601 gcttttagta aattctttgt atgaaggatt ccgactactt tatctttgtc ttcgttataa
      661 acagggattc ttgaatagtt ttcggataaa acttcattca cattttcttc cacagtgtcg
      721 ttgatatcaa tcataaatgc atccgttcgt gggaccatga cttctcgggc aactttcgta
      781 tcaagagaaa aaaccccttg gagcatttct aattcttcat tattcaatac gccttcgttt
      841 tcaagcatat aacgcatttc atctctggtc atttttgaat cttcatcatc aaaagtcatc
      901 ggcgtgatac gcgccaataa acttgtggaa gcagaaagca gccagacgaa gggcttagct
      961 actacaccaa tcaagcgtat cagccctgaa gtgaactttg cgacttcttc tgatttattt
     1021 aaagcaatac gtttagggta caattctcca aaaacaatcg atacataggt caaaatagcc
     1081 agcacaatga tatttgcaat attttttgcc gctgtgccgc cacctaatac cggagctaac
     1141 cgttccgata aagtattagc tagtgaagca ccagacaaaa tgttgaccaa agtgattcct
     1201 acttggattg tcgataggaa attatttgga ttctgcaata tttttaaaag cttttgagat
     1261 ttcacatctc cttcatcagc tttttgctcg attcgattct tattgatcga aacaacagca
     1321 atttcggaag ctgctaaaaa agcattgatc aatgtcaaaa cgatcaataa taaaatctgc
     1381 gctaacagcg actgactctc agggtcagca ttcataatcg cattctctcc ttataaaatt
     1441 aatttttagt ttacgataga aaaaaacgtg gcactatagc cacgttaaaa tggtatcaca
     1501 aagcaatttt ctttgcaata aaaacaagtg tactaaaact acctacgagg tcgtagcaat
     1561 tttcttcttg ttttcatttt gcttgtcttc tttgacgatt ttgattatat aggaaatgat
     1621 cgtcttgcag attgcgtaaa aaggaacacc taagaagata ccaagcaatc cggcaatatt
     1681 tccagctact agaagaacga taatgatcgt taatggatgg attttcagtg atttcccaat
     1741 tacattagga taaatgatat tcccatccaa ctgttggacg attagcacaa ccacacaaca
     1801 aagtaatgct tttaccggat cattgaagac tgttactaga aatgcaggtg ctagtcctag
     1861 ataaggtcct aaatatggaa ttaggtttgt caatcccgca atgaccccaa ataagaaagc
     1921 ataatccaca ccaattacca tatatcctaa aaatgtgaag gtaccaacga ataaacattc
     1981 gattgcttgt ccgctaatgt aattagccaa tgttttattc agttgcccca ataactccac
     2041 aatttggttt cttctttttt ctgggaaaaa ctgttggatg tttggcacta gtttttctcc
     2101 gtctttcaac atatagaaca agatgaatgg tgctgtaatg attactacgg ttgccgaagc
     2161 gatcgttcca acgatcgaac ctaaactatt ggatactcca ctaaggaatt gctgaatgat
     2221 tgtcccgtaa gaaatgtcta attgctcaaa atatttattg atatctactt ccttgaacaa
     2281 aggcaattcg gctacctctt ttaaccagct ttctacctgt ttgatgaaat caggcatatt
     2341 agatgccaat gaggaaattt gctgtactag acttgggatg acactaagta aaatccaaat
     2401 aattgctgca actaaaagga gcagcacaat tgcgacagcc catattcttt tgatttttgc
     2461 tttcatcaac agcttgacaa taggattcaa taaatagtaa agaaagcctg caatcagtac
     2521 aggtgcaaat aacgtggaaa aaaatgtccc gatcggttcg aaaataaagt ttatttctga
     2581 tgaaatcatg atcaatgcag ctatgatcaa taattcaagc gaccaaaaca ttagtttaga
     2641 ctgtctaagt ttttcaaaca atagatttcc tcctttcttt cttactagta tatattatat
     2701 tcgttaaaaa ttcttttatt ctttttttat ttttgaaaac ttgccatact ttttatttgt
     2761 tttattttcc agtatactat acgaaaggaa ggtggctaga ccatgaaagt tgtacaaaca
     2821 aaagatacaa tgagcaatat ttacttagat gctgtacgga tcaggcatca agtttttgta
     2881 gtcgaacagg gtgtgccttt gtctcgagaa atagacaaag atgaagccca ttgtatccac
     2941 ttcgtcctgt actcagataa aaaagaaccg caaggaactg tacgtctttt gcctttagaa
     3001 aacggaaaaa tgaaattaca gcggatggcg attctttctg aatacagaca ccaagggtta
     3061 ggaaaaatat tgattgaaga agcagaaaac tttgctaaga atcaaggcta taatacgatt
     3121 ttattagggg cacagtccac agctgaaact ttttacgaaa aactaggata tacagcttac
     3181 ggcgatcctt ttgaagatgc tggcatgcct catatttata tgaaaaagac tttataaaaa
     3241 tttatttcga aaaaagcaaa aaacagcaag cttttgagaa aaatctctca ctggcttact
     3301 gttctttttt gtgtttactt acgcgacaat tgcttgtaac ggttatacca aatatcaata
     3361 tagccttccg agaacgggcc atctccatta ttgatccagt caaccagaat cttcacattt
     3421 tcttttagga tgaagtcaat atcgttcggg taattcatca ttttgctgtg catctcatat
     3481 tcatcgacat ccaatagtcg tttctcgccg tcaggaaata ccttgatatc caagtcatag
     3541 tcgatatatt tcaaggcctc atcgtccagc aaaaaaggtg aagctagatt acaataatag
     3601 gaaaccccct tttctctgat cattgctatt acattgaacc agtatttttt atgaaaataa
     3661 acaatcgctg gttcgcgcgt tacccatcgg cgtccatcag attcagtgac taatgtgtga
     3721 tcattcacgc cgatcataga gtgttcgctt gtttttaata ccatggtatc tcgccacgtt
     3781 cgatgcaatt tgccgtcgtg cttgtaactt tggatcgtca caaactctcc ttcttttgga
     3841 actcccatag caacccttcc ttaagcagca ttttgtgctt tgtgtttggg tgttcattac
     3901 accgacatca taattattat atcaataaaa atgagctttg cctagaaagg attcctattg
     3961 tttcgatttt tctctaactg atctaccagt ttcatttgga ccttaggaaa aacgaccgaa
     4021 tcaaatgcat caggcttcaa ccacttcgaa gttttgttct cggtaaattc ttgttctgct
     4081 ccctcggttg cccgtccgta aaaaaggaga acatgccatt tcagatgact aaaaatatga
     4141 gtaacttctc ctaaatgtcg tgtctgccaa acaaagagtt cctgcttttc aaatgggaga
     4201 ttttgctctt cttctgctac taggtcatca aacagatcga tttctggctt tgtttcccat
     4261 tcttttttca atcgctcata ctcctcttgt gtcacttcca tcattggaaa tgtccacata
     4321 ttcgccagca atttttggct atctctttct tcaaaataat acgctccaga atgattttga
     4381 agagctgcac tgatataata aacgtctttt ggctttgctt tttttgtttt tacaggaaaa
     4441 ctcgtttgga ttcctcgttt gttagctaaa caaaaggctt ggatcggaca agtctcacac
     4501 tttggagaag ttggtgtaca gatagctgaa cctagatcca tcattgcttg gttgaattca
     4561 cctggatgct tttcatcaat gattttccgc atcgcttcat caaagatttt cctgctagaa
     4621 gcttttgcga tgtctgcttc aatgcaaaac aatctgctga ctactcgcat cacgttgccg
     4681 tcaactgcag gttctggaag tccaaatgcg atacttgcaa tcgcgcctgt cgtatatggt
     4741 cctattccct tcaatgagct aatttcttca ggcgtttgcg gcatttcccc atcaaattct
     4801 gacatgatct gtttagcagc agcttggatg ttccgggctc ttgagtaata accaaggccc
     4861 tcccatgctt ttaaaagctt ttcttctgga gcatttgcta gctcttcaat tgtaggaaac
     4921 cattccatga aacgataaaa ataatcgatc actgtgtcta ctctggtttg ctgaagcatg
     4981 atctcagaga tccagatacg ataaggatca cgattatagc gccaaggcag gtttcttttt
     5041 tcttgttcat accattgaat gaactgatct tgaaattctt ttgtttcttt atctgtccat
     5101 ttttcccatt ctttattcac tttcctcttc cttttccgta atgaatcgct ggatcatatc
     5161 caaatcaaat cctttttgat ataagctttg ctttactttt agatttcttt ttttaggttc
     5221 aaaccttaaa tttcttcgcc atagtttatc tccttgtttg actaaataat catattctat
     5281 ttcttgatct gcttcttgcg gaagatcagc tatcgcttgt tggatcactt cttgagaaaa
     5341 gcctttcgtc atcaatgttt gttggatttt tctcaataat tctttttggc tttttccgtg
     5401 attttttcca aacgcttttt cggctgtctg atgtgcattt tgaacttggt cttcaaatgt
     5461 atattggctg agcgcttgtt caatgatttc aggtttcaaa cctttttgct gcatctgctg
     5521 cgctaatttc tttggtcctt tgtcacttaa gcgcatattc gtgcgcacat aactttcccc
     5581 atagaccaaa tcatcgacaa ggtccaattc ttttaagcgg gctacgattt tatttcgatc
     5641 ttcttgaagg atttcctttt cttttaagta tgttcggatt tctttttccg atcgcaactg
     5701 ataacttaag taattcattg ctaggtgaaa accgaaatca gctccgctac tcttcttgat
     5761 ctcttggata gtttcttcgt ctaattcccg tccttttaat aatcgatagc gtactaatac
     5821 atcttcagat acttgtaaag cttctccttc agataaatct acgcgataga aagggccttt
     5881 gcctttactg attctcgtaa cggttaacat aaacatcctc ctcgaacata tattctctat
     5941 cataccacag aaaatccccg taatcaggta ttatatgtta gaataaacca cagaaaaaag
     6001 aaaaagggag atacttatgg cagaaacaat tgtcaaaact ggacaaacgg ttcctttgaa
     6061 aatcaagcgt ttaggcataa atggtgaagg aatcggttat ttcaaacggt tgatcatatt
     6121 tgttccatat gcactaccaa aagaagaagt actagtgaaa atcacgaaag caactcctcg
     6181 ctatgcagaa ggagaattaa taaaagtcaa aaaaacaagc aaagatcgcg tagtggcacc
     6241 atgtcctgtt tactatgaat gcggtggctg tcaattacaa cacttagctt atcaagctca
     6301 attggatttt aaaaaggatc tgcttttgca agcattggaa aaattcaaac cagcaggctt
     6361 tcgatcttat caacttttgc cgacgatcgg gatggatgag ccttggcatt atagaaacaa
     6421 agcacaattt cagttacgaa aaaataagca gactcaaaaa attgaagctg gtttatacga
     6481 agcaaactct catcagttag tccctataac agactgcttg gttcaagaac ctcgaacaca
     6541 aaaagtaatg aatactgttg ttcaactatt gaataaattt gatgcaccca tctatgatga
     6601 acggacaaac agtggaatct tccgcacaat catggttaga atcggtgtta aaactgggga
     6661 gttacaagtt gtttttatta ctcgcagtaa aaaattcccg caaaaaaacg caatgatccg
     6721 tgagatcaat gaacgactgc ccgaagttgt ttcaatcatg caaaatgtcc aggcacaaaa
     6781 aacgtctctc gtgatggggg atgaaacgat ccacttatgg ggaaaagaag ccattgaaga
     6841 acaaatcaat gaagtgactt tcgatctttc tcctcgtgcc ttctttcaac tcaatcctca
     6901 gcagaccgaa ttgctttatg gcgaaggaat caaagcatta gatgtccagc ctaatgaaac
     6961 gatcgtggat gcttattgcg gagttgggac gatcggctta agtgtagcaa aacaagccaa
     7021 agaagtacgg ggaatggata ccgttcctca agcaatcgct gatgcaaaaa aaaatgcgga
     7081 aagattagga tatcacaaca ctcgatatga agtcgggaca gcagagcaag ttctgcctaa
     7141 atggttgaat gaaggttttc agcctgatgg tatcatcgta gatccaccac gtacgggttt
     7201 ggataacgca ttgatccaat cattattgaa ataccctcca aaaaaacttg tttatatctc
     7261 ctgtaatgtt tctacacttg ccagagatct ggttaattta agtaaaaagt tcaagattga
     7321 atatttacag tccgtcgaca tgtttcctca gactgcacgt tgtgaagttg tcgtgaagat
     7381 gacgagactc gctgactaaa tgaaagaggt tgtgaaaaag tctgccctgt atcaagtaat
     7441 aagaacagcc aaacaaaaat agctcttcat gttttatgaa tactgtactt gtgaccgaag
     7501 agttaacagg aggacactat ttatttaaaa aaagggttgt gacatagttt ttgtcacagc
     7561 cctttttgat tattattgga tattcacgtc tatcacttga taaaatgcat ttgtcgtatc
     7621 gctgatattc catactgcta aaatcacatt atatcctttt cgatcctgcg gaagtgtgat
     7681 cgtttggttg actgtttttg gtggaacagt tgctttgtcg tctatttttg tgatcaattc
     7741 aaaatcacta aatttcaaag gttgattagg attccaagtt ggtttggtaa tgtagtaatc
     7801 ccaagtactt gtccgatgtt gtgctgttaa attccaagta atatttaatg ttcctggatt
     7861 aaccatgttt ttatgccatc tgttagatgt ctgttcatct aaaggctcaa agccgctgac
     7921 tcctgcacta gcaatttttc catcaatgaa tgtatttttg gtagcttcga tactttgcgg
     7981 ttcccattgt gctcttccga cattttgatt taagtttcct gctgctgatg ttcctaggta
     8041 tgcacggctt cctggagaag taatataacc atgcgcaaaa cctggaatgc taaaaccgaa
     8101 caaccctaaa ctaactaacc caataaacaa taacgtacta atctttttca tgtagaaacc
     8161 tccttcattt gataaccaca ttgtaaacgc tttattgtat taacacaaac attatgcttt
     8221 tataatttta tgttgaagta aaaaaggtga aaaaagtaag atgcagatta taacagaagt
     8281 agacgagaaa agtacaaata gaaaacatga gaatcaaatc atatgatctt tttcaaaaac
     8341 atcattcata taaacaaatg ttcaactttt taataacaac aattatcaat ttttttctta
     8401 cttcacaaac taaatacagg tcttgctgtg agccttcatg gtaaactaat attatagaaa
     8461 ggagttagta aaatgaagat gataaaagat attcgttttt gggtttgtgt tataggaatt
     8521 gtcatattag gctttttatc agggttgctt agcggaaatc ccggaaaata ttactattct
     8581 ttgcaacttc caccatttgc accacctagc tggatatttg ggccgatgtg gaccttactg
     8641 tatatattga tgggtatttc tctttatttg ttacttaatc acaacaacaa aaaacagcga
     8701 aacaatcttg tcggtctttt tgtgattcag ttcattttta attttatatg gtctgctcta
     8761 ttttttaatt taagaaatat tttcattgca gcaatcgata ttacactttt agttattttc
     8821 ttgtcagtgc ttatgtatca gttgtggctg catcatcgcc tggcaatgtg gctcatgatt
     8881 ccttattatt tatgggtact attcgcaact ctattgaatt attcaattta ttttttaaac
     8941 taagcgctaa aaagagacgt cctgtaattt aacacataga aaaagtgcca cctaagttag
     9001 attttttgtc taatttaggt ggcactcttt attaaccaaa ctattttttt ctagtaccca
     9061 cttgttgttc catactcatt attctggtca taaccataac cattttgttc ctgtccagcg
     9121 taaggatcat aactttgagt atcttgactt ggtgtatagt actgacttgt atcttctgtt
     9181 tgctgataat aggtattcgg atcttggtac tgatcatatg tgttttctga ataggaagaa
     9241 taatcggtgt acccttcact attcgatcca tcaccgtttg tcgaatcgcc atcttccgaa
     9301 tcatcaaaga acatcattga agcattctca tttttcaaat taggtaatgt atcgcttgtt
     9361 tttatattta attgtttctt cagttcattt tggatcgaaa gaagatcatt ttttcctaaa
     9421 atttgatagt agatatcatt gatcatttgt ccttcgcctt gcaactggtc ttgtttgatt
     9481 gtttcaaacg ccggggtgta gttcgtcgct acatcaagca tgtcatccca atctaagtcc
     9541 gtcgtcacat tgttctcaac tgcttttaaa atttttctat aattgcttac gccatctaaa
     9601 cttaaaactt tattgacgat tttcgtcact acttcccgct gacgacgttg tcgaccgata
     9661 tcgccttctg gatcttcgtg tcgcattcga gaataggcta aacctttttc tccattcaat
     9721 gtttgttcac ctactggtac atggacacca tccaaagtaa agtcaatttt attattcact
     9781 ttgatgccac cgaccgcatt gatcaaatct tccatgccat ccaaattgat cgttacataa
     9841 tgatcaatag gaatatcgag cagttgctca attgaatcca tggccatttc gacaccacca
     9901 aatgcgtagg catgatttaa tttatctacc gttccataac ctacgatatt cgtataaata
     9961 tctcggtcca aactgatgat cgttgatttt ttttgtttcg gattaactgt tactaccatc
    10021 atcgtatcag aacgtccttg ttccgttctt cctaatccac cggtatctaa acctaatagc
    10081 aaaaccgaaa aaggttcttt gtcatcaatg cttactctct cagaacgttt ggaggatatt
    10141 cgattagagt ttttagaaat tttgtttact gtttggctcg cttctcccat aaatctgatt
    10201 ccgtatgctg ataatccggc aatcagcaaa acgaataccc ctaacaaggt taatagaact
    10261 ttttgccatc gcttcataat acacctctgt ttcacatttt ctaaaatatt gtctcatata
    10321 actgttcaat cagcaaattc actttttaat cataagaaaa ctttaaaaaa catttttgtg
    10381 taacgattat tattttttaa aatttctcaa aattcttaac tatcatacca taccgtgaaa
    10441 aagatcgaaa gaccgaatac acgcagttcg caatcgtttt atcttttttt atgtattttt
    10501 tccagaaaaa gcgaacaaca aggtattttc caaataatcg tgcagtaaaa tgatcgcaca
    10561 tacctttccc atctttttaa cagtctttgc ctaccgttca gattatcatt cgatttcacg
    10621 acaatttctt cctatgactg gtccttttgt taaacccatc ttctattcgt tttatttcca
    10681 gctcactgca tggctcttaa aatgactcga actagtgatt gcattaccat catcttttaa
    10741 tggatagata tgctcctctt caaagtaaaa cgattttctt ttaaagtaat agaattgaca
    10801 tggtaatgag tatgtatact agtggtttca caaatggtct tttattcaac atccaaaaac
    10861 tgaaatttct ttaaaatcca ttactaacga agaaaatgtt ccttgcttga taattagtta
    10921 ggacatgtca agtgaacaaa tgcatttact tagccaaaaa atctaaaaac ttcataaata
    10981 gacaaaaaga cacgactctc taagaagtcg tgtcttt
//
LOCUS       DBBGSZ010000066         9928 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.070, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000066 DBBGSZ010000000
VERSION     DBBGSZ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9928
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.070"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            154..417
                     /locus_tag="ACIZE5_002579"
     CDS             154..417
                     /locus_tag="ACIZE5_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HGC6109682.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            417..689
                     /locus_tag="ACIZE5_002580"
     CDS             417..689
                     /locus_tag="ACIZE5_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HGC6109683.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYFRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            766..1095
                     /locus_tag="ACIZE5_002581"
     CDS             766..1095
                     /locus_tag="ACIZE5_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGC6109684.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            1085..1372
                     /locus_tag="ACIZE5_002582"
     CDS             1085..1372
                     /locus_tag="ACIZE5_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGC6109685.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            1658..2515
                     /locus_tag="ACIZE5_002583"
     CDS             1658..2515
                     /locus_tag="ACIZE5_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HGC6109686.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYVEVE"
     gene            2516..3064
                     /locus_tag="ACIZE5_002584"
     CDS             2516..3064
                     /locus_tag="ACIZE5_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109687.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            3324..3785
                     /locus_tag="ACIZE5_002585"
     CDS             3324..3785
                     /locus_tag="ACIZE5_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermophilic serine proteinase"
                     /protein_id="HGC6109688.1"
                     /translation="MKKFKKKIYLGLVVGVSMFGFMAHTKQVTADTNQKERIMSQLDD
                     SQIEYVPNELIVSLKATQRISTEKNKPQNLLGVKVMVEKDLTLRTNESDYNKRDQVLL
                     VKLNEEISVEEAVRTFNASDMVNYAEPNYVVELEPLNDVEEPNTTDSLGNR"
     gene            3829..3915
                     /locus_tag="ACIZE5_002586"
                     /pseudo
     CDS             3829..3915
                     /locus_tag="ACIZE5_002586"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
     gene            complement(3881..4951)
                     /locus_tag="ACIZE5_002587"
     CDS             complement(3881..4951)
                     /locus_tag="ACIZE5_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGC6109689.1"
                     /translation="MKNDIVTYANTKCEEIGISNLEECFFDTNDLSQFLRTGRTNASK
                     LANDLVAKNVLFKINTRPVLFAIKERFEEHFLIPVKDVYESISELKTDLEPNSTDSIL
                     QKMIGYDMSLSDAVEQMKTAVFYPGRGLPMMITGDTGVGKSFFVHTAYQFMKKVNVIH
                     ENAPFKVLNCAQYHNNPELLSGILFGYVKGAFTGADEDRNGLLQDADGGVLFLDEVHR
                     LPPEGQEKLFVYMDGGTYSRVGETIHHASNVRLVFATTEGKEDFLETFMRRIPIHIHI
                     PNIEERGILEKNKLSKILSLAKAKTLARLLMFLLKSLVLHKYSQNILNYYFLEKSKKN
                     RIPNFHLHFQKDLHVDNQFLNQ"
     gene            5553..7397
                     /locus_tag="ACIZE5_002588"
     CDS             5553..7397
                     /locus_tag="ACIZE5_002588"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGC6109690.1"
                     /translation="MNYKQTAEEVLQYIGGEENISHLEHCSTRLRFTLKDNSKVNMSQ
                     LEKVDGVMGVRQNVQCQVIIGNDVVEVYDEVKALLGDNVSNTEEAPKQKQKLGSVLLD
                     FIISIFQPLIPAIAGGGVLKSLLLLASILGLISDQSQTYQILNLVGGAPLYFLPILVA
                     MTTANKLKVNQLVAVSAVGALILPEMTAMLAEGATFLSFGLDNIAYASQVFPAILTVL
                     FYAQLEKWFTKVSPKPIRIFFVPMMSLLITVPIALLLLGPLGYNVGTAFSSIIVSLYN
                     QFGWVATGVLAAVLPLMVVTGMHKAMIPYAVSSMSELGAELLYLPASLAHNISEAGAC
                     FAVSIKTKDKKLKSTAVSAGISALFGITEPALYGVTILHKRVLYAVMFSSLIGGAFAG
                     IVALQAFALVGPGIASITMFADKADPMNLVWAFAVSGISFVVAFAAALVLYKDKEVVN
                     EVETKMETAVVSDAVLSSPVNGKVISLSEVKDTVFSSGMVGDGVAIIPEEGILVAPED
                     GEITMVFETKHAIGLKTANGAELLFHIGIDTVQLEGKGFEAFVRSGEKVAKGQKLIAF
                     DIDLIKEAGFDPTVICVVTNKDNYTIRSFNLEKLVTNDSDLLAISPIA"
     gene            7453..8919
                     /locus_tag="ACIZE5_002589"
     CDS             7453..8919
                     /locus_tag="ACIZE5_002589"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016620473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC6109691.1"
                     /translation="MTNTTSFPKGFLWGGAIAANQVEGAWNVDGKGLSVADMATYKPN
                     LDNKDFAAHMHVTLQSIKEASEDKSDKWYPKRRGVDFYHHYKEDLALFAEMGFKTLRL
                     SIAWTRLFPTGEELEPNEKGVAFYENVFKEMQRLGIEPIVTLSHYEMPLALAVKYNGW
                     VERRVIDDFVRFANVCFDRFGKYVKYWLTFNEIDSIHRHPFTTAGIIQEKSAEGQEAQ
                     DIYQALHHQFVASALVTKDAHEKIPGSQVGCMLTKLMTYPLTCAPEDVELTLKKNLEN
                     NFYADVQVKGEYPALIEKDLENRGIQIKMEDEDREILKKHTVDFVSFSYYMSMAESAD
                     PNAERTPGNTVLGVKNPHLPSTDWGWQIDPKGLKISLIELYDRYQVPLMIVENGMGAV
                     DQVVDGKIHDPYRIDYFKAHFQQMKEAIDEGVDLIAYTSWGPIDLVSAGTSQMSKRYG
                     FIYVDADDEGNGTYNRLKKDSFNWYKEVIETNGASLFE"
     gene            8956..9798
                     /locus_tag="ACIZE5_002590"
     CDS             8956..9798
                     /locus_tag="ACIZE5_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGC6109692.1"
                     /translation="MISIKKVLNSSVVLVEENGKEMIALGKGIGFGQKAGDEISGDKV
                     DKIFLPFEEKKSSQLLELVEEIPIEFFEITRTIVFEAEKGLDKKLNPGVYLTLTDHLH
                     FAVERAQKGVNIANRLYWEIKIYYPKEFQIGKYALTLLNEQYGIDLPKEEASNIAFHL
                     INAQSEDPDSGAGFKYAKMIGGIVNLVRYSLQKDIDTNSIHYARFITHVRFFVERYYS
                     DALLDDGEEEFYNQMWILYPSAMESAAKIKDYIEKVYHKTIPNDEVVYLGVHINRLMK
                     HANG"
BASE COUNT         3430 a         1505 c         2009 g         2984 t
ORIGIN      
        1 ctctaggaaa aaattaacta gcaccacggg tataaaggaa acggataaca ctttacaatg
       61 ctgttttggt actccaattt aaacaaaaca atcgaattta cgtacttaat taagtacgtt
      121 agaatggaga tataaattag agggggagta gatatggcaa aaacagtctt aaatcctagc
      181 tcagcacgga aaaattttta taagttgttg aaagatgtaa atgagaatca tacggaaatt
      241 gaaatcatta gtgagcgcag tgaaaataat gcggtgctta ttggtttgga tgattggaaa
      301 gcaatcaaag aaacgctatt acttgagcaa ataggcactt tgggtgttgt tcgtaagcga
      361 gaaaaagatg atagtggatt tactaatgtt gatgaaattg attgggataa cttataatga
      421 ataactattc tgtgatgatt aaaaactcgg ctaaagctga tttaaagaaa atcaaacagt
      481 ctaatttgaa acctcaattt gagaaggtta ttcagacttt aaaggaagat ccctatctcc
      541 ctacccaatc atttgagaag ttaaaaccta cacatgaagg taggtatttt agaagattga
      601 atagacaaca ccgggttgtt tataaggtag atgaagatga acacgtggtt gaaatttatt
      661 cagcaaggac gcattacgag tcacagtaat tacttgtaaa tacattatct cgtggtataa
      721 tgtatttact aagtaattac atactgttag aaatgaggga tttaaatgat tacaaaaaca
      781 agaaaacaag gcaattcaat catgttgaca gtacctaaag attttaatgt tcctaatgga
      841 gtcgaagttg aagcaaagtt ggtagagaat ggtattcttt atgaatttgt tgaaccacaa
      901 aaagaatttt atgattttag cgaagatatt ttgtctgata taattgcaga aggctacgat
      961 aaagatgaga ttcttgtaga atttaagaat agaaaaaaca aaatgcattc ttcctttaga
     1021 gatattgctg aagatacact tactaattct aaagtaatga ctaaagagga gttggcaaca
     1081 gaaattggct tatgaaatcg ttccttcaaa acatgtcatt aagtatttaa aaaagctaaa
     1141 agagaagcca ttgaaagaaa aatttttgaa tttaatttat gatgaaattg cgattgatcc
     1201 atataagggt gaacaaaaaa ctggggattt atcaggtatt tggtctagtg ggttcaaata
     1261 tgcgggcaca acatatagag tagcttacga gattatagaa aacaaggtta ttccagtatt
     1321 gttatgtgga acgcatgaaa acttttatga acagttgaaa aaattaatct agtgatttgt
     1381 tgtcgttctt aagaaggacg gcttcttttt tatcgaaaat ctgattcgtc tacatgacta
     1441 aagtcgcgag tattctctgc ttctcgataa attaaataac gtcattactt tgaggaaagc
     1501 tataaatcaa tatatttcag cttttcctta tttatgtact accttttact tattaattat
     1561 aaggtagtac atatatatct tttttttggt agtaactaaa aataaatatg ttataatagt
     1621 atcaaatgaa tattgctaaa agaaaagagg taggaacgtg gtagcgaaga aatatgtaat
     1681 cggtaatttt aaaggtggcg taggtaaaag tacgtgcgcg caaatgttag ggtttgaatc
     1741 agcagttaat gaaggaaaaa gaaccttgat aattgacttg gatatgcaag gaaatacttc
     1801 tgatgtgatg aacttaacgc atatgaactt cactaacgaa gaaggaggcg gagaaggtga
     1861 accgattgtt tacgaaaata ctgtgactga cgtgttgata aacaatcttc cacctaaaga
     1921 ggctgtctat aaagtaatca ataacctcta tatacttcca gcagacatgt cctttgaaat
     1981 gtatgatgat tggatcaaag accaatataa tgattcatta tcccaattca aatatatgaa
     2041 agaaaagcta gaaccattat ttgatgagtt tgacgtcatc tatttagatg tcccaccttc
     2101 tatttctgta tatagtaaat ccgcgatgta cattgcggat tgggcaatcg tcgtcttaca
     2161 gacccaagta aaatcgatga gaaatgcgat gcaatatctt gagtatatgg acttttttgt
     2221 gaaagaattt gatacaaatt tatatgttgc tggtgttatt cctttcatgt tggaaagcgg
     2281 tgacgcagta gatcaggaaa tgtataaaca agcccaagag atttatgggg aacatttgat
     2341 taaaaatgtt gtactcaaaa atgcgcgctt aaaacgatac gacggatcag gtattacgat
     2401 ggagaagaca aagaaaggtc tcttaaaaca atgggatcgc aaaagccacg aattatttat
     2461 cagtattttg aaagaattgg aagaacacga gaattggtat gtggaggtgg agtaattggc
     2521 tgacatcaaa ggacttgata tttttgggaa caacaaagga ctcgccaaaa taaaaaaaga
     2581 agcagaagca aagaaaaagc agcaagcaat tacaccatct gaaaataagc aattagaagt
     2641 gcaccaagtt caagaaataa aaacttcctc caatgttgaa agacagagta gaggaagaac
     2701 aaaaaaagtt ggcgcaccaa tcagaaagtt tgataaggtt tattccacca agcatccttt
     2761 aaaactgtcg actttgttaa atgcgacttc cagagtttta gtagaaaagt atgagactaa
     2821 tatgacaaga gatgaattgc ttagaaaagc tttagatgag tatattaaac agaatcttac
     2881 gcaagaagat aaacaagatt tgtttaatga cgtggtgaaa gaactagact tgttcagaga
     2941 aaaatatcca attgttccag aattagatga tcgtggagaa ataataagaa ctaccagtca
     3001 gataaaacaa gataccgaag actcactgcg caaagggtgg ggaatgaata ataaagttag
     3061 ataataatca aagaagaact aagtaactac ctttaaacgg tagttactta gttcttcttt
     3121 gatttgcgtg aaatagaggg gatttatttt tctggttacg tgattaaaaa atccaaaaaa
     3181 tgagcatagg aacggttatg attttagggt gtgttttaat gagatattgt gatttcatta
     3241 ataagtgtat gataatctgt tgttgagtta gtaaataagt aatagagcta actctaaaat
     3301 aaaactatta ggaggagatg tagatgaaaa agtttaaaaa gaaaatatat ttaggattgg
     3361 ttgttggggt gagtatgttt gggttcatgg ctcatactaa acaagtaact gcagatacta
     3421 accaaaaaga aaggattatg agccaattag atgactctca aatagagtat gtacccaatg
     3481 agctaattgt cagtttaaag gctacacaaa gaatttcaac agagaaaaat aaaccgcaaa
     3541 atttattggg tgtaaaagtt atggtggaaa aagatttgac tcttaggaca aatgaaagcg
     3601 attataataa gcgagatcaa gtattattag tgaaattgaa cgaagaaatt agtgtggaag
     3661 aggcagtaag aacatttaat gcttctgata tggtcaatta tgcagagcca aactatgtgg
     3721 ttgaactaga gccgttgaat gatgttgagg agccaaatac aactgattct ttaggaaatc
     3781 gataacgatc ctaattggag taaacaagct aatttaagag agattagcat gccatccgct
     3841 tgggaagaaa ccaagggttc taaggatgtg aaggtagcgg tcattgattc aggaattgat
     3901 tatcaacatg aagatctttc tggaaatgta gatgaaagtt tgggatacga ttttttttac
     3961 ttttttcaag aaaataataa ttcagaatat tctgactata tttatgcaac actagtgact
     4021 ttaggagaaa catcaatagc cttgctaaag tttttgcttt cgctaaagag agtattttcg
     4081 ataatttgtt tttttctaaa atacctcgtt cctcaatatt tgggatatgg atatgtatag
     4141 ggattcttcg cataaaggtt tccagaaaat cctctttgcc ttctgtagtc gcaaaaacta
     4201 aacgtacatt ggaggcgtga tggatagttt caccgactct agaataagtt ccgccatcca
     4261 tataaacaaa tagtttctct tgcccttcag gaggcaatct gtgtacttcg tctaaaaaca
     4321 gtactccacc gtctgcatct tgcaacaatc catttcgatc ttcatctgcg ccggtaaaag
     4381 cacctttaac atagccaaat agtatccccg acaataattc aggattatta tggtattgcg
     4441 cacaattaag tactttaaaa ggagcattct catgaataac gttcactttt ttcataaact
     4501 gataagcagt atgaacaaaa aaactttttc caactccagt atctccagtg atcatcatag
     4561 gaagccctct tccaggatag aagacagcag ttttcatttg ttccaccgca tcggataagc
     4621 tcatatcata cccaatcatc ttttgtagaa tggaatctgt agaattgggc tccaagtctg
     4681 tttttaattc agatatactt tcgtatacat cttttaccgg aatcaaaaag tgctcttcaa
     4741 agcgctcttt gatggcaaat aacactggac gagtattgat tttaaataga acgttctttg
     4801 caactaagtc attggcaagt ttactggcat ttgttcttcc cgttcttaaa aattgcgaca
     4861 ggtcatttgt gtcaaaaaag cactcttcta aattactgat gccaatttct tcacattttg
     4921 tgtttgcata agtcactata tcatttttca tcttataaac agtcctttct aaacttctat
     4981 cccttaaata aatagcaaaa aaaaggaagc aatatcgata tgctgtcctc ttaatttaat
     5041 aaagcgctaa tctaattcac tgtattatca ttttttagta gtatagcaca attatgaatg
     5101 ccttttcttt atatcaaata aagtttatat aaaaaacctc atcctgcaag aaagaaaaaa
     5161 tgaacccatt ctttttatac taggtcttaa aaagacagaa catctgctag aagatagaag
     5221 agaataagag ttatatatgt tggaagatat tcttagaaaa aagacaaaac ttttagaaca
     5281 cgaaaactat attgaacgaa taaaatgaaa aaatgattaa aaaatcattt tattatttac
     5341 gtttacattc taatatgtta aattgaatat aacttaaaca ggcatgtgac tggtaatgca
     5401 ggcaggacct aaataagttg aataacaatg tatgcgtttc aatacacgtt tgccttgttg
     5461 tcaatttatt tagtttctgc ctgttttttg tgttgaggat ggccacttcg actcaaaagt
     5521 tcatcactca aaaaagaaaa gagggaaaca ccatgaatta caaacaaaca gcagaagaag
     5581 tattgcagta catcggtggg gaagaaaaca tatcccattt ggagcattgc tcaactcgtt
     5641 tacgttttac gttaaaagac aacagcaagg taaatatgag ccagttagaa aaagtggatg
     5701 gcgttatggg cgttcgccaa aatgtgcaat gccaagtaat cattggaaac gatgttgttg
     5761 aagtgtatga tgaagtgaaa gcgttattag gtgacaatgt ttcaaatact gaagaagcac
     5821 caaaacaaaa acaaaaatta ggttcagttc tattagattt tattatttct attttccaac
     5881 ctttaattcc tgcgattgca ggtggaggag tattgaagtc cttgttgcta ctagcttcta
     5941 tcttagggct gattagtgac caatctcaaa cctatcagat tttaaatttg gtcggcgggg
     6001 caccgcttta tttcttgcct attctggtgg caatgactac ggctaataaa ttgaaagtca
     6061 atcaattggt tgcagtatct gctgtcggtg cattgatcct tcctgaaatg acagctatgt
     6121 tggcggaagg tgctacattc ttatcttttg gattggataa tatagcgtat gcatctcaag
     6181 tattcccagc catcttaact gttttatttt atgctcaact tgaaaaatgg tttacaaaag
     6241 tttcaccaaa accaattcgt attttctttg tacctatgat gagcttattg attacagttc
     6301 ctattgcttt gttgcttcta ggaccattag gttataatgt aggaacagct ttctcttcta
     6361 tcattgtgtc tttgtacaat caatttggat gggttgcaac cggagtctta gcagctgtac
     6421 tgccattaat ggttgtaacg ggtatgcata aagcaatgat cccttacgct gtttcatcca
     6481 tgagtgaatt gggtgcagaa cttctttatc tcccggcttc attggcacac aatatttcag
     6541 aagctggcgc atgctttgct gtcagtatca aaacaaaaga caaaaaattg aaatctacgg
     6601 ctgtttctgc gggtatatct gcattattcg gaattactga accagctctt tacggggtaa
     6661 cgattctgca caaacgtgtt ttatatgccg ttatgttttc tagcctgatc gggggagcat
     6721 ttgcaggaat cgttgcactt caagcctttg ctttagtggg tcctgggatt gcaagtatca
     6781 cgatgttcgc tgacaaagct gacccaatga atctggtttg ggcatttgca gtatcgggga
     6841 tttcatttgt ggttgctttt gctgcagcgt tggttcttta taaagataaa gaagttgtca
     6901 atgaagttga aactaagatg gaaacggccg ttgtttcaga tgctgttctt tcaagtcccg
     6961 tgaatggaaa agtaatctca ctatcagaag taaaagacac tgttttttct agtggtatgg
     7021 taggtgatgg agtagcaatc attcctgaag aagggatatt agtagctcct gaagatggag
     7081 aaatcacaat ggtatttgaa acgaagcatg ctattggttt aaaaacggct aatggtgcag
     7141 aacttctttt tcatattggt attgatactg ttcagttaga aggaaaaggg tttgaggcat
     7201 ttgttcgttc tggtgaaaaa gtagccaaag gacaaaagct gattgcattt gatattgatt
     7261 taatcaaaga agcaggattc gaccccacag ttatctgtgt ggtaaccaat aaggataatt
     7321 acactatccg ttcatttaac ctagaaaaat tggtaaccaa tgatagtgat ctcttagcta
     7381 tcagtccgat agcttaaaca caagatagtg aaaaaaaata tattgaatga aggaatagag
     7441 gagaatagaa taatgacaaa cacaacaagt tttccaaaag gatttttatg gggcggcgcg
     7501 atagcagcaa atcaagtaga aggtgcttgg aatgtagacg gtaaaggtct ttcagtagcg
     7561 gatatggcta cttataaacc aaatttagac aacaaagatt ttgctgctca tatgcatgtc
     7621 accctgcagt ctataaaaga agctagtgaa gacaaatctg ataaatggta cccaaaaaga
     7681 aggggcgttg atttttatca tcactataaa gaagatttag ctttatttgc cgaaatgggc
     7741 tttaaaacct tgcgcctctc tattgcttgg actcgcttgt tccctacagg agaagagctg
     7801 gaaccgaatg aaaaaggggt tgcattttat gaaaacgtct ttaaagaaat gcaacgttta
     7861 ggaattgagc cgattgtgac actatctcat tatgaaatgc cattagcttt agcagttaaa
     7921 tataatggct gggtggagcg tcgagtaatt gatgattttg ttcgcttcgc taacgtttgt
     7981 tttgatcgct tcggcaaata cgtaaaatat tggctgacat ttaatgagat agacagcatc
     8041 caccgtcatc catttacaac agctggaatt atccaagaga aaagcgcaga aggtcaagaa
     8101 gctcaagata tctatcaagc attgcatcat caatttgttg cgagtgcgtt agtgacaaaa
     8161 gatgctcatg aaaaaattcc aggaagccaa gttggttgta tgttaacgaa attgatgact
     8221 tatccattaa cttgcgcacc agaagacgtt gagctgacct tgaaaaagaa cttagaaaat
     8281 aatttttatg cagatgttca agttaaggga gaatatcctg ctctaatcga aaaggatttg
     8341 gaaaatcggg gaattcagat taaaatggaa gatgaagatc gagaaatttt aaagaaacat
     8401 accgtagatt ttgtttcttt cagctattac atgtccatgg cagaatcagc tgatccaaac
     8461 gcagaacgca caccgggaaa tactgtttta ggggttaaga atcctcattt gccttcaaca
     8521 gattggggct ggcaaatcga tccaaaaggt ttgaaaattt cgttgatcga actttatgat
     8581 cgttaccaag taccgttgat gattgtggaa aatggtatgg gagcagtcga tcaggtagta
     8641 gatggtaaaa tccatgatcc gtaccgcatc gactacttta aagcacactt ccaacaaatg
     8701 aaagaagcaa tcgatgaagg tgtagatttg atagcttata ctagctgggg accaattgat
     8761 ttagttagtg caggaacttc tcaaatgtct aaacgatatg gatttattta tgtggatgca
     8821 gacgatgaag gaaatgggac atataaccgc ttgaaaaagg attcgttcaa ctggtacaaa
     8881 gaagtgatcg aaacaaacgg tgcatcctta ttcgagtagt ctcgatcttt ttaagcagcg
     8941 atagggggat aatgagtgat ttcaataaaa aaagtattga attcaagtgt ggtacttgtt
     9001 gaagaaaatg gcaaagaaat gattgcatta ggtaaaggga taggctttgg acagaaagct
     9061 ggggatgaaa tatcaggaga taaagtagat aaaatatttc tgccttttga agaaaagaaa
     9121 tcttcacaac tattagagtt agttgaagaa atacctattg aattttttga aatcactcgt
     9181 actatcgttt ttgaagcaga aaaaggatta gataaaaaac tgaatcctgg agtctattta
     9241 accttaacag accacctgca ttttgcagtt gaacgcgcac aaaaaggggt aaatattgca
     9301 aaccgtttgt actgggaaat aaaaatctac tatcccaaag aatttcaaat tgggaagtac
     9361 gcactcaccc ttttgaacga gcaatatgga attgatcttc ctaaagagga agcctcaaac
     9421 attgctttcc atttgatcaa tgcacaatcg gaagatcctg atagcggcgc tggattcaag
     9481 tatgcaaaaa tgatcggcgg gatcgtcaat ttggtccggt attcgttgca gaaagatatc
     9541 gatactaatt cgatccatta tgcccgcttc attacacatg tacgtttctt tgtagaaaga
     9601 tattattctg atgctttgtt ggatgatggt gaggaagaat tctacaatca aatgtggatc
     9661 ttatacccgt ctgccatgga aagcgcagct aagatcaaag actacattga aaaagtttat
     9721 cataaaacaa ttccgaacga tgaagttgta tacctaggtg tccacatcaa tcggttgatg
     9781 aaacatgcta atgggtgagc gctcagtaat actattgatg cttttaaaat ctttagagat
     9841 ggattatagt aaaaacaagg tgatttccag ctgtttgtta tctataagag acatttaaaa
     9901 aggattaacg taagataata aaaaatct
//
LOCUS       DBBGSZ010000067         8603 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.071, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000067 DBBGSZ010000000
VERSION     DBBGSZ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8603
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.071"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(132..1085)
                     /gene="menA"
                     /locus_tag="ACIZE5_002591"
     CDS             complement(132..1085)
                     /gene="menA"
                     /locus_tag="ACIZE5_002591"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HGC6109693.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(1098..2201)
                     /locus_tag="ACIZE5_002592"
     CDS             complement(1098..2201)
                     /locus_tag="ACIZE5_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HGC6109694.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(2291..3226)
                     /gene="pplA"
                     /locus_tag="ACIZE5_002593"
     CDS             complement(2291..3226)
                     /gene="pplA"
                     /locus_tag="ACIZE5_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular electron transfer flavoprotein
                     PplA"
                     /protein_id="HGC6109695.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            3528..5462
                     /locus_tag="ACIZE5_002594"
     CDS             3528..5462
                     /locus_tag="ACIZE5_002594"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGC6109696.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5919..6335
                     /locus_tag="ACIZE5_002595"
     CDS             5919..6335
                     /locus_tag="ACIZE5_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HGC6109697.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            6349..6915
                     /locus_tag="ACIZE5_002596"
     CDS             6349..6915
                     /locus_tag="ACIZE5_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HGC6109698.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            6938..7924
                     /locus_tag="ACIZE5_002597"
     CDS             6938..7924
                     /locus_tag="ACIZE5_002597"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HGC6109699.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(8079..>8603)
                     /gene="scm"
                     /locus_tag="ACIZE5_002598"
     CDS             complement(8079..>8603)
                     /gene="scm"
                     /locus_tag="ACIZE5_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HGC6109700.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSD
                     TRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVI
                     GLRITFMSYKKSKR"
BASE COUNT         2527 a         1657 c         1752 g         2667 t
ORIGIN      
        1 tgataaacgg tgttcaaaag cttgcatctg cggtaataag cccaaccaaa cgaaaaatat
       61 aaggagctat ttttatttgg ctgttcttat tacttgatgc agggcagttt tttcacaacc
      121 tcttcatgct gttaaatggc ttgcataatg attgttagta atagccccaa tacataactg
      181 gcattgaata agaccatatt tttgatggaa tagctgaaac tgataggctg gggtaacgtt
      241 tgcttgaatt gatccaaatg cttcttcaca attggcaagg tcaagaaggt gaccaagatc
      301 ggccattcat agataccgct caacaacccc attaaaatca cgaaatagca agcatacatc
      361 aatagctgga ataagactgt tcccgcagga cgtccgatat aaaaaactag tgtatagcga
      421 tgattttcaa tatcacggtc aagatcccgc aaattattag ccaacatgat attggcaatc
      481 gtaaacacca agggtaagga agctaatacg attgctgcta tagcccaaag atttcctacc
      541 aaagcaaatt gtccagatga aaagttgact gtcagatcat agacatctga accgaatgta
      601 ttgacataaa cgaccatggc aaaaattcca aggcccatag tcaccccact gaaaatttcc
      661 cctaaaggca ttcgagataa aggaatcggt ccgaatgtat agaatactcc aataaaacaa
      721 cagataaatc ccatcaaaag taaaagccaa cccgtattga tcgttagaat aacgccgata
      781 acaaaaacaa atgcaatcat agctaaaatc atgtttcgaa tcaatacagg agatagattt
      841 ctgcggccaa tgacattttc ttcatactta tatacttcag aatgagcctt ttcataatcc
      901 atgtaattat tgatagcggt agtcgctaaa tcaaaaacta gcattccaat aaaaaataaa
      961 aaagtgttta gccaatgtat ctcatgaaaa aaagcgatag agaataatac ccctaccgca
     1021 aaaggaaata cactagccac ctttgttcgt atttcaacta cttctaaaaa gatttttagt
     1081 gtcatggttc gtactcctta ttttagttca gaacggtcac ccatcgtgta atgggagtcc
     1141 tccgataatt tgaaggtgtc tttgattgga tcggtcacat atactttatc gtcttttgtc
     1201 acgaagatcg cttccgtccc gttattcaat tcgctttcga cgtattccag tccttttttc
     1261 acacccattg aaaagactgc tgtagacaac ccgtcaccat caattgattt atctgttatg
     1321 atcgtgacac ttgcgatatc attgtcgaac ggataacccg tttttggatc aaacaaatga
     1381 tggtattttt tgccatctac ttctaaataa cgctcgtaaa ttccagaggt aactaatgtt
     1441 ttgttccgtt ctttaataga acctaaaaca gatccgcgag ccatgttcgg atcttggatg
     1501 ccgactgtcc agtcttggtt ttcgcctctt gggctgtggc ctaagacata gacattaccg
     1561 cccaagtcaa cgatggcagt ggtcactcct tgttttttca agactttcac tacttcgtcc
     1621 gtaatgtaac ctttggcgat tgcacctaaa tcgatgatca ttcctttttc ttttagataa
     1681 acagtttttt ctttgtcatt tagttcgatc ttatgataat ccactaattt caatgcctga
     1741 tcgatttctt cttgggaagg ttttctggcg tcatcaaaac cgattcgcca taattgtgtg
     1801 attgcaccaa tcgccatatc gaatccgcct tgagaatctt ggctatattc gtaggcccgc
     1861 ttgactaacg tgtagacgtc atcagaaact tttactggtt tgatcccagc ttgctcattc
     1921 acttcatcga tctcagaacc tttttgattg atcgtgattt tatcaccaag ttcttttact
     1981 cgatcgaagg caggtttcaa tgctgattct ttgccttcat catacacacg gatacgaacg
     2041 taagtcccta acaagaactg ttcatcagaa tatggatctt tcaatatctt ggtagctgct
     2101 gaactttcag tggttgtttt atttgctgag ttgctgcagc cagttagcac cataaaagag
     2161 atgcccagtg tgattaagga aaatagtagt tttttccgca tctttttcct ctcttcattt
     2221 tgaaaggtga gacgactgcc taatctggct atcgtcccac cctccaactt ttattagtat
     2281 gattatgtga ttatttttct gttacgatat tatctacttc gattgtttga gtgtcgcctt
     2341 tttcagctgc attcactaat tgttgtgcgt acatgatgaa tgaatgtgag ctgtgtgtag
     2401 cacctgtaac aacttctaca ttagcaggtg agccatcttc ttcgcccatt gctttgacga
     2461 attcgtcgtt cagagtaggg atgtaagttt ttggttctgt accgcttttt gctttcatat
     2521 tttcattata ttctgtatca tcttgttttg atttaccgtc tttgtcgata taatcaaagt
     2581 ttgattcagt tactttgccg ccagcaactg tcatttcgaa ttgcacacgg tagccgttag
     2641 agtagttctt ttcttcaagc ttgtaagtgc cgtctttcaa atcagcacca ttgtcgattt
     2701 cgattgtatc tgtgttacca gcttgagcag cttggatcaa ttgttgtgcg tagttttgga
     2761 agctttcaga tgagtgagta gctccagtta cgacttccac accgcttgcg ctttgtgctt
     2821 ttaagaattg gtcattcaac tcaggaatgt atttttctgg gtttgtgcca gattttgctt
     2881 ccatgttttt gttgtattct gcatcttttg tttttgattc gccgttttca ttgacgttat
     2941 catattttga ttcagtgatt ttgccgtctt ttacaaccat ttcaaagact gcacggtaac
     3001 catttgaata atttttttct tctaatttat atgtgccgtc ttgcaaatct ccgccagcta
     3061 caacttttgc agatgattct gttgtgcttt ttgcagtcga agattgtgct gtagatgatt
     3121 cagaagaaga gtttgagctt ccgttgtcat ctgcgccgca agcgcctaac actagagctg
     3181 aaaatgctaa tacggcaaat ccagttacaa aacgtttttt cttcatttta ataccccacc
     3241 attccatttc tagtccacaa tttttctttg tgattcatta tacattctaa tctttttagc
     3301 ctataagtca actatttttg ataaataacc catgtaatat ttcaaacgtt ttctttcagc
     3361 aaatttcgtg aaaaaacgct ttattttaaa atttgaaaaa aatccaaaag gagttagaca
     3421 aaagaacaga acatctatat aatatatgga gattgtgtaa taagtatcaa actaaaagaa
     3481 ttatcatata ttcattatat agatagtcta taaggagcgg atgatcaatg gcaaagcaaa
     3541 atattgtcgt tgtaggagca ggatatgccg gtgtttcagc tacaaaatac ttggcaaaga
     3601 aactgaaaaa agaagatgta gcaattactc tgatcgatcg tcattcgtac catactatga
     3661 tgaccgagtt gcatgaagta gctggcggac gtgtagaacc agaagcaatc caatacgatc
     3721 tgcagcattt gtttgctcgt caaaagaatg tacaacttgt cacagacact gtaatcggta
     3781 tcgataaaga acgaaaaatc gtcaagacca aattaggttc ctatcctttt gatcagctga
     3841 tccttggaat gggcggagag ccgaatgact ttggtacacc tggtgtcaaa gcacacggat
     3901 tcaccctttg gtcatttgaa gattctgtaa ggattcggga acatattgag aagacagtag
     3961 caaaagctgc attggaacca gatgatgaac tgcgtaaagc catgctgact ttcgttgtct
     4021 gtggttctgg atttaccggt attgaaatga ttggggaact gatcgactgg aaaaatcgcc
     4081 tagccaaaga ttataaatta gatccaaacg aaatcacact gatggtcgta gaggcaatgc
     4141 cgacgatctt gaatatgttg gatcgaaatg atgctgcaaa agctgaacgc tatttgcgta
     4201 agcacaacgt ggaattatta ttgaatgcac caatcgtaga agtggctgct gatcatatca
     4261 aattgaaaga cggacgcaac attccgactc acacactgat ttggacagct ggtgtcaaag
     4321 gaacttctga cgctgctgac tttggattag aatcagcacg cggacagcgg ttgatcgcca
     4381 atgaatatat gcaggcaaaa ggctacgaag ataaaaacat ctatatcatt ggtgatttag
     4441 tcttttatga agaattccca ggaacaccga caccgcagat cgttcaagct gctgaacaaa
     4501 caggacacac agccgcagcg aatatcgtgg cttcgatcaa aggcggagaa aagcataaat
     4561 ttaaaggaaa ctatcaagga tttatggttt ctattggtgc caaatggggg gtagctaacc
     4621 tatttgataa gatccattta agcggatttt tagctatcgt aatgaaacat atcgtgaatt
     4681 tgaaatactt ctttgatatt cgttctggtt attatatgtt ccaatattta atgcatgagt
     4741 ttttccatat caaagatgat cgcaacgtga ctcgaggaca ttcttctcgt tacggcaatg
     4801 tcttatggag tgtgccactt cgtattttct atggtttagt ttggttcgtt gaagcttcca
     4861 aaaaaatcat tgggaatggt gaagtgttca aaccaagtac ttggtttggt gaaggatcat
     4921 ggttcactgg aaacagtgtg ttcccttgga catgggaata caatgtaaca gatgttgcca
     4981 gtggtgcttc tgctgctggt gatgcaacca cagctgccag cggagcaggg gcaagtgccg
     5041 gagaagcagc gactcaagct gcacattttg gtttgagtta tgcatacggt gaagaaccaa
     5101 tggctgtgat tgagaagtca ccagactggt tcacaaagat catgcaagtg atcatgccaa
     5161 acaatgatgt agcaatgttc ttccaaaaat tcatggtatt ctttgaaatt gccttggcat
     5221 tagcattgat tgctggatta ttcacatggc tatgcagtgc gacaacgatt gtattggtga
     5281 tcacgttctg cttatcaggc atgttttact gggtaaacat ttggttcatt tttgttgctt
     5341 tcgcattgat gaacggttcc ggacgtgcga ttgggttgga tcgctgggta attccatggc
     5401 tacaacgtac actaggtaat tggtggtacg gtagaccaag ttcccagtac ggcaagaaat
     5461 aaatagataa agaacgttat ttgaatgcaa gatttcaata gaaaggggct gagacaaacc
     5521 gtcacagcct cctttttatg taaaattaaa ggaataagat gcccgagata agcctccatg
     5581 agcaagacac aggtgtcaca acctctgtta caacctcttg ttataaacgg tgttccagaa
     5641 gtagcttctt cgaaaaataa gccgaaattt cacaaaaact tgaaaagtaa ttttcgtaaa
     5701 ttccttctta tttcttgaag ttgcccactt ctgtcacaac ctcttgttat aaacggtgtt
     5761 ccacctgctg cttctcggta ataagcccaa agaattagaa aacatggaaa gctgttttct
     5821 attcttcgtt cttattactc aaagcaagac acaggtgtca caacctcttg tttttatgct
     5881 aaaattgggt gagttaatct ggaaaaagga gaacaaaaat gagccttaaa gaatttgctg
     5941 aaaaaagtct gctcaaacct tgggatgttt ttattatttt gcttttgact gttctttctt
     6001 ttttaccagt catgattttt ggtcttcagc aaaacaccgc aacagcagaa aaagaagcgg
     6061 tactgcgtgt ggatggcaca gaaatcaaaa cattcccttt gatggctgga gaagagagca
     6121 acacatatac ttacaaagat gaacacggag attataactt gatcgagata gatggcgatc
     6181 gagtacggat aaaagaagca gattgcgatg accagatctg cgtacgtcga ggctgggcaa
     6241 cgaaaaatgg cgaaaccatc gtctgtttgc cacataaatt agtgatcgaa gtccgttcaa
     6301 cagatggagg tgacgaagac agtctgattt attagacctt cacacaccat gagtaaatta
     6361 caaaaaatga tttatatttc gctacttgtt gcacaaggag tgatcattgg tttattggaa
     6421 aatatgatcc cttatccttt ttcttttgcg cctggtgcaa aactaggctt agccaatcta
     6481 atcacgatcg ttgccatttt taccatgaaa aaacgagaca gcttcttact actttggcta
     6541 cgactattcc tgactacttt gctaggcgga acgatttcca cattccttta tagtatgagt
     6601 ggtgctttgc ttagttattt tggaatgtta ttggtcaagc aattaggacc aaaacgtgtc
     6661 agtatcatcg gaattagtgc ggccggcggt ttcatgcata atgtcggaca gcttttgatg
     6721 gcttctttca ttgcacaatc atggacagtc atgttgtact tgccagtcct ttcagtttta
     6781 gggattttat cagggattgc aatcgggatc gcagcgaatt atcttttacg acatgtgcag
     6841 acacttcaac gattccaaaa agattatgag cagggaacca aacaaaaatg gagcccaatg
     6901 tttaccaaaa aataatcgtc acacaaggag tttttttatg aagctacatc caatgtggga
     6961 aaactatcct gctttaagta aagaattgac agaaacacta aaacggatgg aagaaactgt
     7021 ccgcctgaaa aacaaacctg tcgaacaagc aatcaaagaa acgatccatg ccggcggaaa
     7081 gctgttgcgt cctgcctatc agctattgtt ctcacaattt ggaccagagc aagatcgaga
     7141 caaagccatc gctttggcag cttctatcga aatgctccat acggccacac tgatccatga
     7201 tgatatcgtt gatgaagcgg atctgcgacg tggtcagcct aatatccgta gtcagtttgg
     7261 taatgtcgtt tctgtctatg caggagacta tttatttgtc tgctgtttta aactattgtc
     7321 tgattactcc acttccttga aaagtctcca attgaattct cgcagtatgg aaaaagtatt
     7381 gaatggcgaa ttagggcaga tggatgatcg ctataattat gaactttctg taaaagaata
     7441 tttggaaaat atttcaggta agacagctga actgttccaa ttaagttgtt ctgttggcgc
     7501 ttttgaaagt ggaacaagcg agcgcttcgc aaaaaaagca ggagatatcg gactttctat
     7561 cgggatggcc tttcagatta tcgatgatat tttagattat acaaaagaga gccaggaaat
     7621 cggcaaacct gtactagaag acatgcgtca aggggtctat tctttaccgt tgatctactc
     7681 tttgcaaaaa aacaaaccaa agctactacc ttatttagag aagaaagcgg caatgacaga
     7741 agaagatgtc gacgccgtac gcaaaatcgt tgaacataca ggaggcgtgg aagaagctag
     7801 gaagttagcg gcctcttaca cagaaaaggc tttgaaggaa ataaagaaat tacctgccac
     7861 ctctcttcga acaaaagaga atctcttttc ccttacccaa ctgattttgg atcgcaaaga
     7921 ctgaataggg aaaggttcga tacgtaaata aatttctcag aaggaaatct acgtgttttt
     7981 tgacaaattg aattgtagtt cttgtattta tgataaaaag caaaaataaa gagcaacgtc
     8041 cgttagcgac gttgctcttt tttatcttga atattttttt accttttcga tttcttataa
     8101 ctcataaaag tgattcttaa accgattaca agtaatataa cgcctgcgag tgttatccaa
     8161 ttattcgatt gacttccagt tttaggaagt gctctttttg atttgtttcc attgtcattg
     8221 cttgttttat tagttaagtt aaagttcgtc ctgttatccg aacttgtttt tgagaaggag
     8281 acacttgcat gacgtgtatc gcttgtggta gacgacgtgt ctgtactatc gcttgaagtt
     8341 gatgaatctg agctatcact tgtggtagag gatgtatctg tactgtcact tgaagctgac
     8401 gtgtccgtgc tatcacttgt agtggtagat gaatctgagc tatcacttgt ggtagaggta
     8461 gtatctgtac tgtcacttga agctgacgtg tccgtgctat cacttgttgt ggtagatgta
     8521 tccgtactgt cgcttgaagc tgacgtgtcc gtgctatcac ttgtggtaga ggtagtatct
     8581 gtactgtcac ttgaagctga tgt
//
LOCUS       DBBGSZ010000068         8083 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.072, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000068 DBBGSZ010000000
VERSION     DBBGSZ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8083
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.072"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..286)
                     /locus_tag="ACIZE5_002599"
     CDS             complement(<1..286)
                     /locus_tag="ACIZE5_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC6109701.1"
                     /translation="MTYTHLTPNELVMIEVYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIAKRSTEGWTPDVIIG"
     gene            921..1814
                     /locus_tag="ACIZE5_002600"
     CDS             921..1814
                     /locus_tag="ACIZE5_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGC6109702.1"
                     /translation="MGKISLGIDIGGTFIKYALIDKQHRIKEKWKVETVKYNTADEFY
                     DYICSNIRNVDEIDKIGVSAPGLIDEDSNVKSYAAPNVAIMYGTNINNEINKRTNKKV
                     SAINDAKAAGLCEFKIGNAKGYKSSAFLIIGTGTGGCICDENGVVYGKDSFAGEFHNM
                     PFVNAEIGGLDKMGDYASITGLVNLYNKKANREEQVQYGNEVCKKYLNGNESAVSSVD
                     EWIGNIVAQLIVITVFYNPEVICIGGGISEENWFINKVRETYKKTCREYLEADFITTE
                     INRCKHNNDANILGAVIKASI"
     gene            1888..3327
                     /locus_tag="ACIZE5_002601"
     CDS             1888..3327
                     /locus_tag="ACIZE5_002601"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC6109703.1"
                     /translation="MIYEELDKFQDDFLWGSASAAYQVEGAWDKDGKGESVWDVYTRQ
                     PGTTFKNTNGNIAVDHYNRYKEDVALMAEMGLKAYRFSIAWTRIYPNGRNEVNEEGLK
                     FYENLIDELIANNIQPIITLYHWDLPQHLQDLYGGWESREIIHDFNEYCVTLFKRFGN
                     KVKHWVSLNEQNIFVTLGYVTAMHPPAVKDQKRMLEANHIANLANATVIESFKKYVPD
                     GMIGPSFAFGPVYPFSCDPKDVLSAENAEDLNCNWWLDVYCKGKYPVFAFKYYERLGI
                     APTIEDGDLELLERVKPDFIGINYYQTSTVAFNPLDGVGQSEGINNTGKKGTTKESGL
                     PGVYKNAKNAHLETTNWDWAIDPTGLRIGLRRLTSKYNLPILITENGLGEFDKLEEDD
                     TVNDAHRIDYLSAHIKACKEAITDGVDLLGYCTWSFTDLLSWLNGYQKRYGFVYVDRD
                     ENDQKDLRRIKKNSFYWYKNVIRTNGEEL"
     gene            3375..3677
                     /locus_tag="ACIZE5_002602"
     CDS             3375..3677
                     /locus_tag="ACIZE5_002602"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC6109704.1"
                     /translation="MKKILLVCSAGMSTSLLVTKMRNSAKEKGIEVEIDALPVAEAST
                     AVDNVDIVLLGPQVRFQKGTVEKLVKGRIPVEVMDMRLYGMMNGKAILEDALQKIN"
     gene            3696..5060
                     /locus_tag="ACIZE5_002603"
     CDS             3696..5060
                     /locus_tag="ACIZE5_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC6109705.1"
                     /translation="MSFMDKFQSAIERLLVPLSTKLNAQRHICAVRDAFILSFPLTMA
                     GSLMVLLNNVFLSADGFMFKILQFDKLFPGIVKFQAVFAPVVKGSADIFSILIVFLIA
                     RNLAKLMEGDDLLTGLTAISVYFIIYPDYFDNEGVNYLTNQYMGAQGLFVAILVGLLV
                     GELMSRLAKSDKLEIKMPEQVPPAVARSFKVLIPIIITTVFFSVLNYFVKMAAPGGLH
                     ELIYNIIQTPLTRMSQSLFSVIILALLSQLLWAMGIHGPNTIAAIRDTMFSEAGNANL
                     LHYAESGTTWGAPFPITYSGLATAFAEYGGSGATLGLIIAILIFSKNKESKSIGKLSF
                     VPGLFNINEMVIFGLPIILNPIYIIPFIIAPLVNIMIGYTAVMILKIMPPVTIGIPWT
                     TPGPLMPFLGTGGNIVALFVGFICLAVSVLIYSPFVIAANKAAIIEDEMENEIQSQEV
                     VESI"
     gene            5116..5430
                     /locus_tag="ACIZE5_002604"
     CDS             5116..5430
                     /locus_tag="ACIZE5_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGC6109706.1"
                     /translation="MEGIELTAFSIISNVGMAKSLAIEALRDARKGKYNEAEKKMAEA
                     SEYFVKGHHAHTSLIQKEAAGEKVELSLIIMHAEDQLMSTETTKLLIEEMIEMFKQLN
                     NK"
     gene            5764..6810
                     /locus_tag="ACIZE5_002605"
     CDS             5764..6810
                     /locus_tag="ACIZE5_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6109707.1"
                     /translation="MMNSTEIAKIAGVSRSTVSRVINNYSNVSEETREKVLRVIKEHE
                     YVPHASARMLAGSQNKVIGLFIIDLIHEEVGLKNRITKSPYYLEFTSSVIETASEMDY
                     LVLVHIIHSVAGYEKIKESFYNKTISGGIFIGQNDDDESIKTIIDRGYKVVLLDQSIR
                     PEDATYNQCMIVNADNYNGAYCATKYLIDKKHKQIAHITGGTVKFSSKDRIRGYKKAL
                     EDAGIEVNKNLIVNSEFVENAGYEAAKKLFNGNSEFSAIFASNDKIAFGAIKAIQERG
                     LKVPDDISVIGFDDIESSKYFNPPLTSMKMKLGEMADIATKSIVASIEGETKPSINVV
                     PVSLVERESCGILQ"
     gene            7365..7919
                     /locus_tag="ACIZE5_002606"
     CDS             7365..7919
                     /locus_tag="ACIZE5_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109708.1"
                     /translation="MKQLLSKLKKIWAVLPEHSLKQRIGNNLALIYSGALLIQDILGY
                     PLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLTNSDNKHTPSTI
                     WGKVSIKKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNMCAEKGRRTKRI
                     HMNRQVLPTYEILLPSSLKSYFRL"
     gene            7938..>8083
                     /locus_tag="ACIZE5_002607"
     CDS             7938..>8083
                     /locus_tag="ACIZE5_002607"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF013579.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGC6109709.1"
                     /translation="MKVRHHVIKQLKDIPIPMPAISEQQKIGTFFKQLDDTITLHQRK
                     LDLL"
BASE COUNT         2791 a         1258 c         1679 g         2355 t
ORIGIN      
        1 ggccaataat gacgtctggg gtccaacctt cagttgatct ttttgcaatg tattcttttt
       61 cctcagcagg aaaaatgatt tcggttctcc cacaacgtcg cttattttct ttgtattgtt
      121 caaagtattc aagtgctgtt ccaccacatt tgagaaagtt atagacattg taaattgttt
      181 ggcgtccacg tttaagctgc ttcgcaacga tggcaaccgg agtttcttga tgaaaatata
      241 cttctatcat tacaagctcg tttggtgtaa gatgggtata agtcatttat gttcactctc
      301 cttgtatgct ttagcgggta ttacgatttg agtgtaacat aaatggcttt tttatttgtc
      361 tcgcttaatt atacaaacgg cgtcattaga aaatgatggt aaattatttg atggtaacgg
      421 tgatgtaaca acggtaatga aattattgct ttaacagttt agcgtgataa aaatctatac
      481 cttcttaagt tgatttatta acttgagaag gtattttttt ctgaaaaatg ataatgaaaa
      541 tcaaaatgtt catttctatc aattttgaag tcaaaaaaat aaagtacagc ccagaaattt
      601 gctctgtact ttaaaaaact agttaaatga agatgaaatc gctcccttat tttttagtat
      661 tggtggaatt aaaaggtact ttttaaacaa aaactacaca taaaaaataa aaaaaataaa
      721 aaaagtattg aaatgtaatt gctttcagta tatgctatat ctataaacgc gcgttcatgg
      781 gatgttcatc gtataaaaaa aggtggaaat gagcgtatcg tttttctttt taacaaatca
      841 tgaacgcgcg tttatgagtt tgaatcaagc tgcaatataa gaaggcaaac tgcaagacct
      901 tcattttaag gagaagtgtt atggggaaaa taagtttagg aatagacata ggagggacgt
      961 tcattaagta tgcattaata gacaagcaac atcgcatcaa agagaagtgg aaagtcgaaa
     1021 cggttaagta caatacagcc gacgaatttt acgattatat atgttcaaat ataagaaatg
     1081 tagatgaaat tgacaaaatc ggtgtaagcg cacccggcct tattgatgaa gattcgaatg
     1141 ttaaatccta tgctgctcct aacgtagcta taatgtacgg cacaaatatc aataatgaga
     1201 tcaacaaaag gacaaataaa aaagtgtccg caatcaatga tgcaaaagcg gcaggtttat
     1261 gtgagtttaa aattggaaat gcaaagggat acaaatcttc agcgtttttg attataggta
     1321 caggaacagg cggatgcata tgcgacgaaa acggagttgt gtatggaaaa gattcgtttg
     1381 cgggggaatt ccataatatg ccttttgtaa acgctgagat aggcggcctt gataagatgg
     1441 gtgattatgc ttcgataacc ggattggtta atttatacaa taaaaaagct aatcgggagg
     1501 agcaggttca gtatggaaat gaggtttgca agaagtacct aaacggaaat gaatcagctg
     1561 tgtcttcagt agatgaatgg ataggaaaca tagtggctca attaatagta atcaccgttt
     1621 tttataatcc tgaagtgata tgcatcggtg gaggaatatc cgaagaaaac tggttcatca
     1681 ataaagtaag agaaacgtat aagaaaacct gtagggagta tttagaagcg gattttatta
     1741 ctaccgaaat caatagatgc aagcataata acgatgccaa catactgggt gctgttataa
     1801 aagcttctat ctaaaataca caacagtttt gtttcaagaa agaatgtttg aaaataaatt
     1861 tatattgaaa acgaaggaga agattcagtg atatacgaag aattagacaa attccaagat
     1921 gatttcctat ggggatcggc atctgcagcg tatcaggttg aaggagcatg ggacaaagat
     1981 ggaaaggggg aaagtgtatg ggatgtgtac acccgccaac cggggacaac atttaagaat
     2041 acaaacggga atatcgcggt cgaccattac aatagataca aagaagacgt agctttaatg
     2101 gctgaaatgg gattgaaagc ttatagattc tcaattgcat ggacacgtat ttatcccaat
     2161 ggaagaaatg aagtaaatga agaaggctta aaattttatg aaaacttgat agatgaactt
     2221 atcgcgaaca atatccaacc aatcattacg ttgtaccatt gggatttacc tcaacatctt
     2281 caagatttgt acggcggatg ggaatcaaga gaaatcattc atgattttaa tgaatactgt
     2341 gtaacgttat tcaagagatt tgggaataaa gttaagcact gggtatcatt gaatgaacaa
     2401 aatatatttg taacactagg ttacgtaacc gctatgcacc cgccagctgt taaagatcaa
     2461 aagagaatgc ttgaggcgaa tcatatagcg aacttagcta atgctaccgt aattgaatcc
     2521 ttcaaaaaat atgttccaga cggtatgatt ggaccaagct ttgcatttgg accagtttat
     2581 ccattcagtt gcgatccaaa agatgtttta tccgcagaaa atgcagagga tttaaattgc
     2641 aattggtggc tcgatgttta ttgcaaaggt aaatatccag tgttcgcttt taaatattac
     2701 gaaagacttg ggatcgcacc cactattgaa gatggagatc ttgaattgtt ggaaagagta
     2761 aaaccagatt ttatcggaat aaattattac caaacaagca cagttgcatt caatccgctt
     2821 gatggagtag ggcaatcgga aggtatcaat aacacaggta aaaaaggcac cactaaagaa
     2881 agcggattac ccggagttta taaaaatgca aaaaatgcac atctggaaac aacaaattgg
     2941 gactgggcaa ttgatcctac tggtttaaga attggactaa gaagattgac cagcaaatat
     3001 aatcttccaa tacttattac agaaaacggg cttggagaat tcgacaagct tgaagaagac
     3061 gacactgtca atgatgctca cagaatcgat tacttgagcg cacatatcaa ggcttgtaaa
     3121 gaagcaataa cagatggtgt tgatcttcta ggctactgca cgtggtcatt tacagatttg
     3181 ttaagctggt tgaatggtta tcaaaaacgc tatggatttg tgtatgtgga cagagatgaa
     3241 aatgatcaaa aagatttgag aagaatcaaa aagaacagct tctattggta caaaaatgtt
     3301 attcgcacca atggagaaga gttataagaa tcgttcacaa tcaatgaata tgaaaaaaca
     3361 aggagagata gaccatgaaa aaaattttac tagtatgttc agcaggaatg tccacaagtt
     3421 tgcttgtgac caaaatgaga aactccgcaa aggaaaaagg aattgaagta gaaatagatg
     3481 ctcttccagt tgcagaggca agtacggccg ttgataatgt cgatatcgtt cttttaggac
     3541 cacaagtgcg tttccagaaa gggaccgttg aaaaacttgt aaaaggcaga attcccgtag
     3601 aagtgatgga catgcggctg tatggaatga tgaatggaaa agcgatttta gaagatgctt
     3661 tacaaaaaat aaactaggaa aggaggctaa aaaaaatgag ttttatggac aaatttcaaa
     3721 gtgctataga aagattgtta gtgcctttat ctacaaagtt gaacgctcaa agacacatat
     3781 gcgcagtaag agatgctttt attttatcat tcccattaac gatggcagga tcattgatgg
     3841 tgttattgaa taatgttttc ttgtcagcag atggattcat gtttaaaatc ttgcaattcg
     3901 ataaactttt tccgggtatt gttaaattcc aagcagtgtt cgctccagtt gttaaaggtt
     3961 cagctgatat tttctcgatt ctgattgtgt ttttgatagc cagaaacctt gcgaaactaa
     4021 tggaaggcga tgatttgttg acaggtttga ccgcaatctc tgtttatttc atcatctatc
     4081 ctgattattt cgataatgaa ggagtaaatt atctaacaaa tcaatatatg ggcgcacaag
     4141 ggttgtttgt agcaattttg gttgggctct tggtcggcga actaatgtct agattagcaa
     4201 aatcagataa gttagaaatt aaaatgccag aacaagtacc tccagcagtt gcaagatcct
     4261 tcaaagtgtt gatcccgatt atcatcacga cggttttctt ctccgtcctc aactactttg
     4321 taaaaatggc tgcaccgggc ggattacatg aattaattta taacatcatt caaacaccat
     4381 tgaccagaat gagtcaaagt ttattctcag tgattatttt agcattatta tctcaattgc
     4441 tatgggctat gggaatacac ggaccaaata cgattgcagc tattcgagat accatgttct
     4501 cggaagccgg aaacgcaaac ctcttacatt atgctgaaag cggtactaca tggggagcgc
     4561 cttttccgat aacgtacagt ggtttagcta ctgctttcgc tgaatatggc ggttcaggag
     4621 cgacattggg tctaatcatt gctatattga ttttctcgaa aaataaggaa tcgaaaagta
     4681 ttggcaaact ttcttttgta cccggtttgt tcaatataaa cgaaatggtt atctttggtt
     4741 taccgattat tctgaatccg atttacatta ttccatttat tattgcgcca ctggttaaca
     4801 ttatgattgg ttataccgca gttatgattc ttaagattat gccgccggta acgattggta
     4861 ttccttggac aacaccagga ccattgatgc ctttcttggg tacaggcgga aatatcgtcg
     4921 cactgtttgt cggattcatc tgtcttgcgg tgagtgtatt gatttactcg ccgtttgtaa
     4981 tcgcagcgaa taaagcagcg attattgaag atgaaatgga gaatgaaata cagtcacaag
     5041 aagtagtaga atcgatttaa aaaagctgca gtacgctgag aacaaaccga aagattcaag
     5101 ataggagatt tacacatgga aggaattgaa ttaactgctt ttagtataat cagtaatgtt
     5161 ggaatggcca aatcattggc tattgaagca ttaagagatg ccagaaaagg aaagtacaat
     5221 gaagcagaaa agaaaatggc tgaagcatcg gaatattttg tgaaaggcca tcatgcacat
     5281 acttctttga tacaaaaaga agctgctggc gaaaaagttg aactttcgtt aataatcatg
     5341 cacgcagaag atcaattgat gtcgacggag acaactaaat tattaatcga agaaatgata
     5401 gaaatgttca aacagttaaa caataaataa gtgaacatga aagagaaaat attagacgaa
     5461 ctagaattgc ttgcttactt tacaggcaga atctgatgcc agcagcaaaa catagagcac
     5521 ccaggatgaa atataatcct gggtgcctta tttttagaac aaaacaccgg ggtggtagtt
     5581 tgttctgcgg ttgaaggcat ttgctgatgg tttctgcatg aaaggtattg ccaaaagtct
     5641 ccttttgctg gaatcctgaa gcaggcagag tttttcgaaa aacagaaaaa gattgaaaaa
     5701 aatggacaaa taatatagtg ttgcagtatg aacacgagtt tacgaacgaa aggagatgcc
     5761 tttatgatga atagtactga aattgcaaaa attgccggag tatcacgcag tactgtatcc
     5821 agagtgataa ataattattc aaatgtctcg gaagaaacaa gagaaaaggt tttaagagta
     5881 attaaggaac atgagtatgt gccacatgct tcagcaagga tgcttgcagg aagccaaaat
     5941 aaggtgatcg gcttatttat tatagacctg atacatgaag aagttggact aaaaaataga
     6001 attaccaaaa gtccgtatta tctagaattt actagttcag tgatagaaac agcaagtgag
     6061 atggattacc tggttcttgt ccatattata catagcgtcg caggctatga aaaaattaaa
     6121 gagagttttt ataataagac aatttctggt gggattttca taggccagaa tgacgacgat
     6181 gaatcgataa aaacaatcat tgatagaggg tataaagttg tgctgctcga tcaatcaatc
     6241 agacctgaag atgccaccta taaccagtgc atgatagtga atgcggacaa ttacaacggc
     6301 gcttattgtg cgacaaaata tctcatagat aaaaaacata aacaaatcgc acatattaca
     6361 ggcggtacgg tcaaattctc ttctaaagac aggataagag gatacaaaaa agcattagaa
     6421 gatgcaggga tagaagtaaa taagaacttg attgtaaata gcgaatttgt ggaaaatgct
     6481 ggatatgagg ctgcgaaaaa attatttaat ggaaatagtg agttttcggc tatttttgcc
     6541 agtaatgata agatagcatt tggagcaatc aaagctattc aagaaagagg tctcaaagtt
     6601 ccagatgaca tctctgttat aggatttgat gatattgaat cgtctaaata ttttaatccg
     6661 ccattgactt ctatgaaaat gaagttagga gaaatggctg atatcgccac aaagtcgatt
     6721 gttgcatcga ttgaaggtga aacgaagcca tctataaatg tagtacctgt ctcattagtg
     6781 gaaagggaga gttgtgggat tttgcagtag caaaacttgc tgaattagtt ggagctgatt
     6841 atttgattat tttgattgag gtagacaatg tctgtgtcta tgtcgacttg aaaagtaaag
     6901 tacagcgccc aaaaatgctc tgtactttaa atctcagcaa aaacaggaat atttcccaaa
     6961 catctccttc tttgagtaat tatacaaaaa ttatgcagac tttctttttt catgataaga
     7021 taatttaaaa agtttttaaa cgatttctcc tcctcttttt cttatatcgg gggagcatat
     7081 ttttttgtag actaggggat tataagttca gccatcaatg tctagctccc aagtcctgac
     7141 ctagtgaaaa aaagataaat ttgccccatt gcgcgcttcg ctgctcattc agggtcaaat
     7201 ttcctatttt ttcataggtc aaggcggact tgtccgcttt tcttatatta agtttacaaa
     7261 ggatgcgaat cacgcagaga aagttaaaag tctttcttct aatacttttg gttggggtat
     7321 aaagttattt cttttgaaac tctttgaaca agggattgca aaaattgaag caacttttgt
     7381 cgaagctcaa aaaaatatgg gctgttttac ctgaacattc tttgaagcaa cgcattggta
     7441 ataatctagc tttgatttat agtggagctc tcctaattca agatatactg ggctatcctt
     7501 tacgattaga gcatatacag acggtgctta ttaattcgta cgaacagtta atcgtagata
     7561 ctagtttagg aagtgagcaa acggtatttg accgagtgaa aacattgttg gtgatgaata
     7621 gccataaatt tttaacaaac agtgacaaca aacatacgcc cagtacgatt tggggaaaag
     7681 tatcaattaa aaaaaatggg gatattaagg taaatatttt tcctatcccg tttgaggact
     7741 tgttaaggcg agaatttcaa gtaaaggatc taacctatct ttttagacaa ttgcttgatt
     7801 cgggtaatat gtgtgcagaa aaagggagaa gaacgaaacg tattcacatg aatcgtcaag
     7861 ttcttccaac atacgaaatt ctattacctt cttcactcaa atcgtatttt cgattgtaat
     7921 ttagaataaa ccaaagtatg aaagtgaggc accatgttat taagcaactg aaagatattc
     7981 ctattccaat gcccgctatt tcagaacaac aaaaaatcgg cactttcttc aaacaactcg
     8041 acgacaccat tacccttcac caacgtaagt tagatttact aaa
//
LOCUS       DBBGSZ010000069         7625 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.074, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000069 DBBGSZ010000000
VERSION     DBBGSZ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.074"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(14..712)
                     /locus_tag="ACIZE5_002608"
                     /pseudo
     CDS             complement(14..712)
                     /locus_tag="ACIZE5_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
     gene            791..967
                     /locus_tag="ACIZE5_002609"
                     /pseudo
     CDS             791..967
                     /locus_tag="ACIZE5_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            complement(1143..1712)
                     /locus_tag="ACIZE5_002610"
     CDS             complement(1143..1712)
                     /locus_tag="ACIZE5_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HGC6109710.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1786..2109)
                     /locus_tag="ACIZE5_002611"
     CDS             complement(1786..2109)
                     /locus_tag="ACIZE5_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109711.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2263..3075)
                     /locus_tag="ACIZE5_002612"
     CDS             complement(2263..3075)
                     /locus_tag="ACIZE5_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109712.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3402..4277
                     /locus_tag="ACIZE5_002613"
     CDS             3402..4277
                     /locus_tag="ACIZE5_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HGC6109713.1"
                     /translation="MGKRSTIQLMIVALLACGHVLFEDIPGVGKTLLVKALAKAVQGT
                     FSRVQCTPDLLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLE
                     AMAENHATIDNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDD
                     ELLLLLDKFEKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAI
                     QLGISPRGSLSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKK
                     QIIHTLVAQIPIPVR"
     gene            4291..4614
                     /locus_tag="ACIZE5_002614"
     CDS             4291..4614
                     /locus_tag="ACIZE5_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109714.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KNKRF"
     gene            4611..5363
                     /locus_tag="ACIZE5_002615"
     CDS             4611..5363
                     /locus_tag="ACIZE5_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HGC6109715.1"
                     /translation="MILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKR
                     EISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKL
                     SAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPELLILG
                     NRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKD
                     RTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5353..7524
                     /locus_tag="ACIZE5_002616"
                     /pseudo
     CDS             5353..7524
                     /locus_tag="ACIZE5_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2272 a         1512 c         1370 g         2471 t
ORIGIN      
        1 agggggggat tttttatcgt tgtggaatat ttaaatacca acgcttgtca tgaaaatctt
       61 gtgctccacc cttagtattt ccttctggat cgtttgtcgc acgcatcatg acgtatactt
      121 tcttattagg gaaatcacgc atattgaaag atacatgata gccaacattt cctaaagtat
      181 tataagcttg atttacgtct ggtctataaa tcccatcagc tcttactcta gctagttctt
      241 ttccagtatt gtagtccata atgaaaatat actcgtattt ataattagca atgtgccatc
      301 cagctacatg caagtttgcg ttttcgattt ctccgaactg atcaatgtgg gcgtaatttg
      361 ttccatctgt cagcgtagaa tttgcagcac ctgctcgagt tggatcaatt actggtttat
      421 cctccgaagt agttggatta tcatccgtaa aaccatgagc caaatcatag gctagttttt
      481 ctttacttac acctatttca gaaagataac cgtaaggatc tgtatgatcg ccccaaatat
      541 tttgtgttac ccataaatgc gatttgattc ctggttggtt ataaggagtg tctaatgtta
      601 atggaatacc atatttcatt gctgaatctc ttgccaattc aacgtatact ttatagttct
      661 tttcaaaagt ttctttatca tgtgtgtgtt gtaactcgat ttgcacagga cttttggctc
      721 acgaggttgt cctactctac atcttgctga tagatatgct gaaaggaaaa caccaacatt
      781 atgttttgct ttttcagcta gaacgagaca agcaggaata cctttagaag atatcaaagg
      841 ttttttaggt cataaagatg tttccactac acaagtctat gcccatattt ctcccgaagt
      901 gaaaaaaaga tcaatgaatc aactagaaaa ctatatagaa gagcaaataa aaaagcactc
      961 aaattgagtg cttttttaag ctcactatca ctaaaactat cactaatttt atttataagc
     1021 gaacatgttt ctatcactga ttttttaaat ctagcgaaaa acccttatct taaaggcgtt
     1081 cgttcaattc tttggcaagg tcttcaaagc ctggcttgcc tagaagtgcg aacatggttt
     1141 tcttatagct catgtagaaa aattttcttg atgatgattt tatccatcaa ttgagattga
     1201 ctgttttgct ctcctatgat ttcagctatg attgtccgat tttgcggttt tcttcttaac
     1261 tggtagttga ttttcccagt ttccatcaac tcgctaagca tatccacgac tccgccaaat
     1321 ccggtctttt tcgtaataaa acctagtgct accattcgtt catctagatt ttttgctgta
     1381 atcgtcacac cagtaatgag cgagtgctgt aatgtttggg ccagctcttc catcccttca
     1441 gcattggata cgacggaagc tgttttgtta ataggttctt cgtttatttc ttttggttct
     1501 ttcctctcca ctttcactgt ttgacgaagg acatctagtt cttgcaagag cgtttcgtat
     1561 tgttcttggg tcagcatcac gccagctact ttttcacgat taaatatata tacgccagtt
     1621 cccgcgtctc gcgcttgagc aaatacatcc atcggcgatc gtttcacttc tgtgatcgaa
     1681 gatgtgggaa cttctaattt ctttaattcc aatggatttc ctcctttact aatcgctttt
     1741 tattatagca cagactgact tgttttgatc ttttttccaa aggttttatc ggtttttgcc
     1801 taaccagtaa ttgatatcgg taagaagtct ttcgatacca aatgaaggat ggtacagata
     1861 cgttttttga tcttcgttat ggtctagtgg aaaaaaatga tcgatgatca ctagatctgc
     1921 ataccgaggc ggcttatttc gagtacatac atgtatagag atccgttttc gatgtcttag
     1981 cgttttgttc agtaccccag caagtcttct tgcttcttgg tgttcatagc gaaaaaaaaa
     2041 gacgattttc acttcaggag ggtggacatc taaataccct cgttcctgga gtgttttcag
     2101 taaaagcatc ccccactcta ctgcggggtg tgcaagtgct tgttggatcg ctagccgaaa
     2161 ttgatatagt ttatctttgg aattgggaaa tttttctaat gtttcctgat aataacgaac
     2221 ttcttctatc agccggtcat ggataccaat tacgtaacga agtcattctt ggtaaagtac
     2281 ttttgtcagc tttgatttgc tttcgctctc aaattcgcta ttcagccaaa acagcgaatc
     2341 aagcttttca gtcacaatcg tcaatttccg atagtcttgt gtctcttcta tccgtttcca
     2401 ccgcttttca gtaatctggt tacagctcaa gcgcaaaatt gctagataat ttttttcttt
     2461 tattggcaaa atctgctcct ctctaaatag caattcagga aacaattcaa agaatagtgt
     2521 tcgactgtct cctaaaatct cgatttctgc cggatccttt ctttgcttca ataattggat
     2581 gaacatctca gaaaaggact gctctccatc atctgcaaaa aaatgcggaa aatctttcaa
     2641 aaagcaaaac agcagatatc ttacttttct ttctgaacca aagatctgtg cttttttata
     2701 agaaaaagaa aggtggtact cgccaaacca ctttctcaat cgctcttgcg tagaacgatc
     2761 gtacttctgc tcgtaaggtt cattcaatag cagatttttc agtaaacaaa acgggggtga
     2821 ttggatcaga aaaacaaaca agagataagg ttcgctatat ccttgatcat aaactaactg
     2881 aacggttttc ttatgaagaa tcagctgaat gggacagtcg ctttccgcca aacgtttcag
     2941 atgccgatcc actgttttaa catcgatttt cagttcttca gctaaatcag cttttcgcca
     3001 gatcaaatct ttcattagat tgattagtga aaataaattc tgtgcatttt ttgataatag
     3061 tttttgccat ctcatcgatc atttctcacc tgatttctaa acatattgtt tgatcaaaat
     3121 gggttcactc ctaaaaagat aaaaaactcc ctttctattt atttaaatac gcaaatcttc
     3181 ctcattattt tttattttac tcaatttaat cgtattctca tttcaaaacg aatgtacttt
     3241 aaaaaaacat aataagatca ctttgcttgt aggatgtatt cccttccatt acaatgaaat
     3301 aaatagcgat tttatgagaa ggtgatgtga aaatggaaga aaaaatagaa gaatccaaac
     3361 aaaaaatcga tcagttgata taagaattag aaaaagcggt catcggcaaa cgttcaacta
     3421 tccaattgat gatcgtggcc ctattagcat gtggtcatgt cttattcgaa gatattcccg
     3481 gtgtaggtaa aacgttactg gtcaaagcac tagcaaaagc tgtacaggga accttcagca
     3541 gagtccaatg tactcctgat ctgctgccta gtgatattct tggtttttcc gtatacaatt
     3601 cacaatcaaa agagtttgaa tttcgtccgg gaccgatctt taccacgatc ttgttagcag
     3661 atgagatcaa tcgtacgact cctcgtactc agtcagcact tttagaagca atggccgaga
     3721 atcatgcaac gatcgacaac aatacatacc ctctagacaa tcattttttt gtcttagcta
     3781 cgcaaaatcc aatcgagtac gaaggaacat atcctttgcc ggaagcacag ctcgatcgtt
     3841 ttttattccg actacaaatc ggttatcctt cttttgatga cgaacttttg ctacttttgg
     3901 ataaattcga aaaagtgttg gataacttaa atgaagtatt gaacagttat gaaatagaag
     3961 aaataaaaac aaatgtggcg aatgtctttg tcagtcccga agtggcatct tatgccttgc
     4021 agttagtgtc agcaacaaga agtcatgctg ccatccagct tggcatcagt ccacgaggaa
     4081 gcctttcctt tattcaggca gcaaaagctt atgctttaat ccatgggaga aattacgtca
     4141 cgcccaaaga tttgcaggat ttagttcctt acgtgttttc ccatcgcctg attttttacg
     4201 atcgttcatt gaaggaagac gaaaagaaac aaatcattca tactcttgtt gcacaaattc
     4261 ctattcctgt gaggtagatt gaggtagaca atggaaaaaa tcaaagatta tttcattaat
     4321 tttgtgttat ttctggtata tttcatcatt gtgctttttg ctcttgtatt caacaattct
     4381 ttaggctggt tcttgttggc cttttttact ctttatgtat catggagctt gatttcatta
     4441 agcagctttc taaagaaact ttcggttact tgtacattgc agccactcgt ttatcgcaaa
     4501 aaaagtatgc aggttatttt ttccatagca aaaaagagaa ctttttcttt acctctccct
     4561 cgtttacaaa tcggcttccc agcaatcttt gcagaaaaaa acaagagatt ttgattctta
     4621 caaataaacc gcaagaagtc caattgcttt ggcagccaaa agaaagagga tgccatgaaa
     4681 cattaactgt catttttaca gcctatgata gtctaggact tttcagaaaa agtgcaaaaa
     4741 gagagatctc ttttcctgtg actgttctgc ctgctttttg taagattcaa gcagaaaaat
     4801 tacagagagt tctggaaaaa aaacagcagc tgaacgcgta ccaaagaggt cttgattttc
     4861 gggaacatcg cgcttatcgt ccaggtgatt ctttcaaccg aatcgattgg aaattgtctg
     4921 ctcatactca agagtggtta taccgtgaat acgattatca agaagaagaa tgttctcctc
     4981 ttttttgctt ttggggttcg cccagtccaa aatttgaacc tctgctagac ttgtattttt
     5041 ctttatggca tttgagaaaa gaaaagcagc cggaacttct gatattaggc aaccgcgcct
     5101 ttcatggcaa agaccccggt catacctatt ttgcttcttt ggaagctggc gatgagaaaa
     5161 cttttttcgc acacttgaaa aaatatgcaa aaaaacaaat cgtcctcttt gttcctgaga
     5221 attctcctga agtctcagaa gctattgaaa cattgtcaaa agatcgaacg gtttatcttg
     5281 tttatttcgt agaaaaacaa ctcatggtcc aagaaaaaga caagatatgt tcattgccag
     5341 gaggtgaatg gattgacgat taaacgggaa aaatggctgc gtggcgttta ctcctttgtg
     5401 atactaagtg taggtgctcc gatatttgta gtagctaatc aattgcaaaa cagctacctt
     5461 cttatcctaa ctattggtgt cctatgcctt attgtctgct gtattcctaa aaaatgggta
     5521 cgtttgctgc tttctttgcc agtaatgata ggttgtttgt ttttatattt tccttcgaag
     5581 acattttcca tattatggat cttacagttt ttttcgtcag ttacagagga attcttccat
     5641 ctatcccaag gtaaacttta ttatttgcca gaaaagacag ctttttttct cataatgttg
     5701 ctgatctatt tatttattac attgaccgtg gattacgact attggtacgc accctttctt
     5761 tctttgatgg cttacttcat gatgcttacc gtttttcgga aaaaagattt actgtacgaa
     5821 atgattgcgg tagtaactgt tttgttcgtg tatctggcag caaggcaatt tttctccatc
     5881 cggttgttgt cgagaaacac tcgattccag tcattgacta cagttctgct tatttgtttc
     5941 ttaactttta gcgctatctt gcctttatat cttccgaaag tacaccaatc tctcgaggaa
     6001 acgagtgaac cgatccgaga atatcttaat gatgaagggc tttatgacac actccatgag
     6061 tatcaattaa ccggaagtgc aagaacaggc ttcagtgaga atgatgaaca gcttggtgga
     6121 cctttatatg ataatggcga agttgttttt acagcgaacc aaaaaggaaa tggctattgg
     6181 aagatcgaaa ataaaaatca ttacaccggt tctggatgaa tagaagatca ggacgcaccc
     6241 atccaaccaa tccaagaatt ccctgttgac atcacgagct accaaaccgt tatagaagac
     6301 aaagaaaaca ttacattgac cctaaaaaaa caagctttct taccttatcc ttatggaaat
     6361 actaccttga ctgatttttc attagctagt ggacaaacgc tttactattt gcctgaaagc
     6421 cagcgattca ttcctgtccc gaatgaatcg acacgttctg caactttaca aacagaaagg
     6481 ttagttttta cgagagaaga attaaaaagc agtcagttaa aagctgatga tttagaaaat
     6541 cagcagacaa atcttcaatt gccaaaaagt ttgcctaaac gtattgagga cttggcggtc
     6601 gaattgacca aaaatgaagc aactttaatt cgtaaagtcg aagctgtcta acagtattta
     6661 aaaacaagcg gaaatttccg ctattccaaa acggataccg ggcatactcc aaaagaacac
     6721 gattatgtgg attatttcct ctttgattca aaagtcggct attgtgacaa cttttcaact
     6781 tctatggtcg tccttcttcg aacacttggt atcccagctc gctggacaaa aggttttaca
     6841 aatgggctca gaacaggcac agataatcaa gggaatgagg aatacagcat tctcaatagt
     6901 catgctcatt cttggccaga ggtatacttt cctggatttg gctggcttcc atttgaacca
     6961 accccttcat ttgccaatcc aatgggttca caaccagttg ctgaaacaac cgaaaccgtc
     7021 cagcctgcta tcgaacaacc aaatgaaagc gaaaatatgg cagaaactat ttccagtgag
     7081 agatctgagg tcattccatc agaagaaaca acactcacac cagcttataa aatcgtctta
     7141 ttcagccttg gagtgtgttt atccgtcttg ttgttctttc tattgttatt cagaaaatct
     7201 ctgcgctgga caagttatct tatctatctt catttttttg cttctactaa tacgattgca
     7261 tatcaaaaac ttcttaaccc tttggaaaca ttggtaccgc gcaaacccgc agaatctttg
     7321 caggaatata gcctgcgaat agaacaagaa ttcaagctag atctgcgttt cattcgatta
     7381 actactcaat atgaagcaga aatatatgga cgacaagcag atccggtaaa attcgataaa
     7441 aaaacctatt tagaaataac gcatataata agaaaaacgg tatacaaaaa aattctgaca
     7501 aaagggagcc gcttcaaaaa ataagataaa atttctggag aatctacttc tcgaatgccg
     7561 agaaccagct gattgagtat cgattactcg aaaaaaaggt tgtgacacgt tttttgtcac
     7621 aacct
//
LOCUS       DBBGSZ010000070         7597 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.075, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000070 DBBGSZ010000000
VERSION     DBBGSZ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.075"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(135..425)
                     /locus_tag="ACIZE5_002617"
     CDS             complement(135..425)
                     /locus_tag="ACIZE5_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109716.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(543..803)
                     /locus_tag="ACIZE5_002618"
     CDS             complement(543..803)
                     /locus_tag="ACIZE5_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109717.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(940..1353)
                     /locus_tag="ACIZE5_002619"
     CDS             complement(940..1353)
                     /locus_tag="ACIZE5_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HGC6109718.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1809..2294)
                     /locus_tag="ACIZE5_002620"
     CDS             complement(1809..2294)
                     /locus_tag="ACIZE5_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109719.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2433..2648)
                     /locus_tag="ACIZE5_002621"
     CDS             complement(2433..2648)
                     /locus_tag="ACIZE5_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HGC6109720.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2872..3672
                     /locus_tag="ACIZE5_002622"
     CDS             2872..3672
                     /locus_tag="ACIZE5_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HGC6109721.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3691..5559
                     /locus_tag="ACIZE5_002623"
     CDS             3691..5559
                     /locus_tag="ACIZE5_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HGC6109722.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELCDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5552..6043
                     /locus_tag="ACIZE5_002624"
     CDS             5552..6043
                     /locus_tag="ACIZE5_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HGC6109723.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6031..6585
                     /locus_tag="ACIZE5_002625"
     CDS             6031..6585
                     /locus_tag="ACIZE5_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HGC6109724.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6603..>7597
                     /locus_tag="ACIZE5_002626"
     CDS             6603..>7597
                     /locus_tag="ACIZE5_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HGC6109725.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2706 a         1213 c         1444 g         2234 t
ORIGIN      
        1 gttactatga ataacataat aagaaagtaa agtggattga tttgagatct ttttatactt
       61 caaaaaagat aacacccaac tttcaaaaat atgttttgga agttgggaca aacgagttaa
      121 tacattttaa tacattattt tttattcaaa aaaaatagca caatggcaaa gatcgtaaga
      181 gagatcataa gccccaatga atgactaaaa agaaaagcag aatcacatgc catatcatcc
      241 catatttctt caagaaaata aataagcggg aaaaagggaa ggaatagtag aacatcgatc
      301 cagcaccatt tttttcttct tttgaaataa cataaaacaa taaacatgaa cgtgcaggga
      361 agtaaaaaca aagctttact cataactaac aaaataccag ctccttttat ttttttctcc
      421 cccacattca aagagtaaca atggtatgta cttaataata gaaaaatgga tcaacttgta
      481 tgaataacag ctgaaaagat ctgcaccaaa taaaaaactt ccagccaaaa ctgactggaa
      541 gtttattttt ttctgaaata ttctaacaca aatatgaaaa agatggccga agctaataag
      601 ccgatttcgt agcaaaacaa tgagatacca gagtcgtaat aataaaatcc tctaatctta
      661 tggataaaat agatcatcgg acaagcagat aagagtaagt atttgttagg ccttttgaat
      721 aagtaaaaga aagcactggt cattatgata aatggtatcc aaaacaaaag tttacttaag
      781 acaatcaaat gatcaactcc catatttttt accaagagag atcataacat ctttatcgta
      841 aaaacaaaat atttttttgc tcattttgaa aatttaaaca tactcgttct tatccaaata
      901 tataaaaatc gcccctcatt catcgagagg cgataagttc taatttaact caattttttt
      961 tgtttctttt ggctgataag ctgttttagg taataccaat ttcagcacac cgtttttaaa
     1021 ggttccagtg attttttctt catcaacatt aggaagatag aatgaacgtt tgtaagagac
     1081 cgaatgtctt tctttccgta catagttgcc atcttcttta tcttctgtat gggactcatg
     1141 attggcggag atcgtcaaag tattatctga atattcaact gtcgtgtctt ctttgtcaca
     1201 gccaggcata tcagcagtta gtttgtattc tttttcattt tcgactaaat ctacttttgg
     1261 ataacttgaa acacctaaaa aatcattgaa tgctggacta aacacgtcat tgaaatcagg
     1321 gaacatgtcg cgaatgctag gtacatttgc catttttgat catcctttca ataagtattt
     1381 tttatttatc cctatttacg taataactct attttgaaaa aaatgcaagt ataatggtta
     1441 gctttgtgaa tatttcatct aatacgatac aaaggctatc tttctaattt gaaaaaggga
     1501 tcattaaaat aataagaaga aaatatgtca aaaggtaaaa aagtaaattc ttctatccaa
     1561 atatagaaaa attgaatcta gaaaaccgcc cgacaataaa tttcattaac tcagttgacc
     1621 gaaaatgaag tagataccaa aaatttatca agagagcaag tagagaagtg agtatattca
     1681 taagagaaat agctgtaacg aattattagg ttaatgcaaa tgcttattta tactccgtat
     1741 aactttctca gaaaaaatga taccaataat gacttgctag tactgtaaat ccgtataata
     1801 tcatctaatc aaaatggtgt tccatttgca tctgtcatcg taatcgatcc ttcgggtgac
     1861 actcgataaa aaccaacgct tccagatcct ccttgggaac ggatttgttt gctggaagct
     1921 gtgaacaaat aatctcgatc aattttttga taaaagctaa taacaatatc gtcactttgt
     1981 aattcggaac ggtgggcaat aagaaataga agtgctttgt cagagttttc taatggaaga
     2041 gaaggtacag tgctttcttg catttcagat gttgaagaaa tgctaaacga ctgaatactt
     2101 gattggctat gttgcgaatc tacattacca gtagaagtat tagtaatgga agtagtagaa
     2161 gtacttttag ttgaaccaac ctcagttgtt gaaatggctg ctgaagattc tttaacagaa
     2221 ttctttgttt tatatccaca ggcagaaaaa agtattacag ttcccaacaa gcctgcgtaa
     2281 atccctttat gcatgatagc tcctcctaaa atagattatc tttattcagt atatcactta
     2341 aacaaagaaa agcagatggt ttaaaatgaa aaaaccttcc caataaaggg aaggttcatg
     2401 aagataataa cttttttaat aattatagct ttctaatatc tttcatcaac ttttctagta
     2461 atcattggga aaaatttcaa gcagtagatc gcacaaatac ctacgacgat ataaatgatc
     2521 ttcgcaaaaa tagttgttga accaccagca atcatagcta ctaaatcaag ttcgaacaag
     2581 cctaccaaca gccagttcaa ccctcccaca atcaataaag ttaatgcaat agcatctaaa
     2641 gttttcatta gaattctcct ttcttaaatg ataaaacaat tatatatcaa aaagagaaac
     2701 attgcttata taacgctcag gaattttagc aatctatgca aaaagatgaa aatttttttt
     2761 gctcttccat tagtacacat tttttagctg aagctgtaaa tttcatgtct taattttttt
     2821 tagtgagctt ttatactgga tttgtaagaa aaaagaagga gaggatcaca tatgtcggat
     2881 tggttggata ttgcaggaaa agtagtaatt gtaactggag gttcctcagg aattggaaga
     2941 agtatcgtcg aaaatttgtt gaagcagaat gcacaagtag cgaattttga tgtaactgaa
     3001 tgccgtatac agcatgaaaa cctactatct ttaaaagtcg atgtgtcttc taaaacggac
     3061 atagaagaag ggatatataa agtaatgaaa catttcaaga cgatcgatgg tctagtcaat
     3121 aatgcaggaa taaatattcc ttctcttcta atagatagaa atcatccaaa aagcaagtat
     3181 gaattatcag aacaagtttt tgataagatg atcgctgtca atcaaaaaag tgtatatttg
     3241 atgagccaag cagttggaag aatcttggtg caaaagggat caggagtgat cgtgaatctt
     3301 tcttctgaat caggattgga aggatcagaa ggacagagct gttatgctgc tacaaaagca
     3361 gcgatgaaca gttttactcg ttcttgggca aaagagttag gaaagaggaa tgttcgtgtg
     3421 gtaggtgttg caccagggat actggaagaa accggtttga gaacacaaga atatgaagaa
     3481 gctctttctt atacgagagg tataagcgtc gaacagctga gaaacggtta cagtcgaaca
     3541 agtacgatcc ctctaggaag gagtggtaag ctgcaagaag tggcggatct agtctgctat
     3601 tatctttcag aaagatcaag ttatatcact ggagtcacga ctaatatttc aggaggtaaa
     3661 acaagaggat aaaggatagg ggggacgcac gtgacgctag taaacagatg gtaccaatta
     3721 ttgaaattac tagtcactca caagaaagtt tcaatccagg aagtgcaaaa agaaatcaaa
     3781 accagtaatc aaaccataaa aaaagatatt ggggagttga atgaagaaat tgccggtatt
     3841 gcaaaaatca tccaaaaaaa caaacatttt gaacttgaaa tttatgattt tgattttttt
     3901 gatgagatca tgcaaggaaa attgaaaaca gccagtgatt tcaattcggc atccaaaaga
     3961 atcgcttatt tactaaatag gctgatcgaa acagaggatt tcttacgtat ggatgatttg
     4021 tctgaagaag tcggtgtcag cagaggaaca gtggtcaagg atctaaagac attaaaagag
     4081 atgatcaatg attttgatgt aaagattaca ggcacaccaa ataaaggact aagaataata
     4141 ggagatgagc tagaattacg actactttta ttttattttg tttctcccta cttttcagag
     4201 acgaaaacag aacagtttct agaagaaaaa caagcaatca aacattttca gaagaagacg
     4261 aatgctagta aacaagaaat caccctttta acgaaagtta tcggtatttc tttgaataga
     4321 atctctagta actatctgtt gaagaagccc atcaatcgtt acagtgggtg ttttgaatat
     4381 atccaagaat tcaatgaact gatcaatcag ttggaagaaa tctatgaact aactttgagc
     4441 caatatgaaa aagattttat cagttttcct ttgaacatca tcaacacaag tataacgatg
     4501 ataaggaaag ctaactctga tttgcgctta tatttcgacc ccatgatgat gcgtattcga
     4561 cgattagatc tcattgatct ggatgagtcc ttcttatatc aagagatgaa acagcacctc
     4621 tctttattga taaatcgggt aatttttcgt tatcgattga ctgatttatt ttatggtgag
     4681 atagaaaaaa agtatccttt ttcttaccaa atcgctagcg aatgcataca agcattagaa
     4741 gctatcttgc aacataagat ctctaaagta gagatcagct acctaacgtt gtatttggag
     4801 ttagcatttc gatatcaaaa agagcatttt tcctctaaaa aagtagccat tgttcatacg
     4861 acaggaaaag gaacagcatt aatgatccaa agacaaatca aaaggatatt ggggagggat
     4921 atacaaataa cacatgtttc agaagaacaa tatgaaaaag tagatctaaa caaatatttc
     4981 gctgttttta caacgattcc gttaaaaaat gtaaatgaag agacaccggt gatccatttg
     5041 actaatcttt ttgatgactc ttggttaagg gcacaatggc aaaaagcaaa aaaaaagcga
     5101 ttagccgggt ttcattctac tgtttttttc tatcaaatat ggaaagaaaa aaagacgtat
     5161 caagaatatt taaacaaatt agtcgctcct ttgatcagag gctattatgt ggatgaagaa
     5221 tttgaaaaaa ggatcttgaa aagagaatat cagcaaagca catttgttaa caaagaattt
     5281 gcttttcctc acacaaccaa ccagctatct caacacattg ttttatcagt agggctaata
     5341 actgatcaag gtttagcaga aacaggagga aatggagtta tttttttatt tgccatacct
     5401 gaagaaatga cggctgaagt tgagaatgaa ttatttgagc tatgcgatat cctatttgaa
     5461 ctcataaaaa tgggaataga tgagtttatt gaattagcac cgacacaaga atcattttta
     5521 aaactaatca aaagtaaagg agagagactt catgaatgat atgtatctat tcatagtttt
     5581 cgcagcttca gcttatgtgc tgcaagcagt tatcagttgg aagcaactaa agcatttcaa
     5641 tcaaacatat agcgaactgc gaagaaaagg aaaagtagcg attggtaaac gacctgggaa
     5701 aatccgttca ggcacgattg ttatgctagc tatagacgat catgatcaag ttttagaagt
     5761 cagaaaaatg caaggggtta catctttggc aaaatttcat tcattacctg tctatgcggg
     5821 tgaagatatc cattacatcg atcgttacca tccctcagtt cgagcggaag atcgtttgac
     5881 acaagcagct ttagaaaatg ccagagaagt atacttacga atagaggcag gaaatgaaaa
     5941 aagtgaacaa ccttcattgc cttttattgc tatgctcaat aattttcgga tatggaaaag
     6001 tacgatcaaa gaaaaaagga gtgacaaacg atggatatca taacaaaatt tgctgaggga
     6061 tttatgaggc tgttccaaac aggtgcagaa acattcataa gctggatgac aggaatcgta
     6121 ccagttgtct tgatgctgat ggttgcaatg aatacgctga ttgctttttt aggtgaagac
     6181 cgagtaacga aagtagccaa attatcagcg aaaaatccgc ttactcgtta ccttgtgtta
     6241 ccgttcttat ctgcttttat gttgggaaat cctatgtcat ttacaatggc tcgtttcctt
     6301 ccagaatact acaaaccaag ctattatgct gctcaagctc aattttgtca tacgagcaat
     6361 ggtgtattcc cccatattaa tcctggagaa ttgtttgtat ggatggggat tgctcaaggg
     6421 atcgaaacct tagggctaaa ttcgatggag ctggctatcc gatacttgct tgtgggactg
     6481 ctgatgaact ttattggtgg ttggataact gattttacta ctggatttgt atgcagacag
     6541 caaggaatcg ttcttagcaa aaaagtagag ctttcagttg attagagaaa ggagagtttt
     6601 aaatgtatgg tgatattaag atcgtaagag gaaacggcgg gtatggaggt cctttgatta
     6661 ttaggccgac aaaagataaa cacaagttca tctatgtcac aggtggaggt gagaggccaa
     6721 tgatcgtaga taaaatagaa gaactgacag gtatggagtc tatcaatggg ttcaaaacat
     6781 caatacctga tagtgaaatc gcgcttgcaa tcgttgactg tggagggact cttagatgtg
     6841 gaatttatcc taaaaaaggg ataccaacca tcaatatcgt ttccacagga aaaagtggcc
     6901 cattagcaca atatatcact gaagatattt atgtttcagc agtagggtta gaacaaatac
     6961 agccactaat ggaaactgat gataacaaag aaacagtaaa tactgcatct ccagataaaa
     7021 agtacaaata tgatacttct aaaaagataa ccgagcaaaa agcagagcag caaaactgga
     7081 tagcaaaaat tggaatgggc gcgggaaaag tagttgctac attcaatcaa tcagcaagag
     7141 aagcagtaga tacgatgatc cggacagtga tcccttttat ggctttcgtt tcccttttga
     7201 ttggtgtgat acaaggttct gggatcggta atgtatttgc taacattatg gcacctttag
     7261 caggaaatgc agttggatta acaatcattg gctttatttg ttcactgcca tttttatctc
     7321 ctttgcttgg tccaggggca gttattagcc aagtgattgg aacattgatc ggtgtagaga
     7381 ttgggaaagg aaatattcct ccccaattag cattaccggc actatttgct atcaatactc
     7441 aaaatgcatg tgattttatt ccagtcggtc taggtttgga agaagcaaaa gctgagacag
     7501 tagaagtagg tgtaccatca gttctttatt caagatttct taacggcatc ccacgagtta
     7561 tcattgcttg ggtagcaagt tttggattat atagctg
//
LOCUS       DBBGSZ010000071         7548 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.076, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000071 DBBGSZ010000000
VERSION     DBBGSZ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.076"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            118..1259
                     /locus_tag="ACIZE5_002627"
     CDS             join(118..346,346..1259)
                     /locus_tag="ACIZE5_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGC6109726.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
     gene            1494..1946
                     /locus_tag="ACIZE5_002628"
     CDS             1494..1946
                     /locus_tag="ACIZE5_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109727.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            1960..2649
                     /locus_tag="ACIZE5_002629"
     CDS             1960..2649
                     /locus_tag="ACIZE5_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109728.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            2774..5125
                     /locus_tag="ACIZE5_002630"
     CDS             2774..5125
                     /locus_tag="ACIZE5_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="HGC6109729.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            5205..5600
                     /locus_tag="ACIZE5_002631"
     CDS             5205..5600
                     /locus_tag="ACIZE5_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109730.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            5925..6542
                     /locus_tag="ACIZE5_002632"
     CDS             5925..6542
                     /locus_tag="ACIZE5_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6109731.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            6583..6882
                     /locus_tag="ACIZE5_002633"
     CDS             6583..6882
                     /locus_tag="ACIZE5_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HGC6109732.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            6916..7083
                     /locus_tag="ACIZE5_002634"
     CDS             6916..7083
                     /locus_tag="ACIZE5_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HGC6109733.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(7128..>7548)
                     /locus_tag="ACIZE5_002635"
     CDS             complement(7128..>7548)
                     /locus_tag="ACIZE5_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6109734.1"
                     /translation="SLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNELLD
                     TAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRLV
                     FKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT         2597 a         1140 c         1503 g         2308 t
ORIGIN      
        1 gattcatcgt tattcctcct gctatctttt tctattattc tatcttattt gatagtagat
       61 ttaaaacttt gcaacagaac cgtagaatct aactactaag aaaaggacgt gtccacgatg
      121 gcaaaagcca agaaaaaatt tgatgaagac tttaagaaga tgatcttaga tttaaaccag
      181 tctggccaat cggtcgaaga actggcagcg caatatggta tcgctacaca aacgatttat
      241 cgttggaaga agcttcatac aaagaatgta gcaaccggca tgactgaggc agaaatccta
      301 gcgatgaaaa aggaaatggc ccgcatgcag gaggaaaaca ctatcctaaa aaaggcttta
      361 accatattcg ctcaaaagta aaaatgagtg atgtcttcga atttattcaa tcaaatgttc
      421 atgatcatga cgtaaaacaa atgtgtaccg ttttggaagc accgaaatcc agctactatg
      481 actggaagaa aaagaaacct tccaagcgcc aatcagaaaa caaacgctta aaccgcttga
      541 tttcaggaat ctactttgaa aacaagggta tctatggtgc gcctaaaatt cataagattc
      601 ttgttggccg tggcgagacc ttgtccttaa agaaagtaca aatactgatg agaaaattag
      661 gcttgcgttc agtcaccctc aagaagtaca agcctggcaa acaagcgaaa gttaaaagtg
      721 aaggacgtaa aaacctgtta aaccaagatt ttaccactac gtcgatcaat caaaaatggg
      781 tgacagatat tacctatatt cataccctaa aagatggctg gacctacctc tccactattc
      841 aagacctcca cacaaagaaa gtcatcggtt ggaagtttgg caagcagatg acgaaagaat
      901 tggttatcga aacccttgac aatgcgctct taaaccaaac accctccgag aacttgatca
      961 tccactcaga tttgggttct cagtacacta gcgaagccta tgaggcaaag ctgaatgaat
     1021 tgaacattcg gcactccttc agtcgtaagg gctgtcccta cgataatgcc ggtatcgaat
     1081 cgtttcacgc ctcactcaaa aaagaagaag tctatccatc aaaagcgtat gaaaactttg
     1141 aagctgctta tttagcgtta tttcaataca ttgaaggatt ttacaatcgc aagcgaatcc
     1201 atagtagtat caactattta acaccaaatc agatggagga gttggcattg caagcttagt
     1261 tcctagctac cacttacatt tttttggcga gatttccaca gggtttcaac ttcatcgctt
     1321 cgatcagcgg tcaaacggtt ttggtttgac cgctggtcga aacgatgaga tactcacccg
     1381 ctggaatctc gaaaaaattc tcacaaatcg tgtccgaggt attgactcaa atccaccaat
     1441 tatcttatcg tagatatata ttataaattt aataagaaag cgaggtgaga atcgtgaaaa
     1501 aaacgatact aagtattttt tcagtattta caatattaat tgggggctat tttcttttga
     1561 atttagattc tgttaattca aacgctcaaa taaaagatca aagagtagct gaacataata
     1621 ataaaaaaat gagtttgacc aaaaatatct attctatgtc agatgaagaa ttgtataaag
     1681 aatttggtga tttatccggg gaacagttag aagaaagtat tccaggaatt agtgactcag
     1741 ataaaattgt tgtcttgtct gctggtgggc aattaatggg agatggcaaa tccgaattag
     1801 ttagttataa acaaaatcac agacagttta ttgatgttaa tactgattcc aacgctattt
     1861 cgattaagga tctaaaagag cttttaaata gtaaaagaaa tgaattaaag cagataaaag
     1921 aaactaattc agtggaatta gagtaaagga agattcatta tgaaaaagat ttttggtgtt
     1981 tctgttgggc tacttatgat gttaacattt ggaaatgcag tatatgctgc tgagaaagaa
     2041 gttatttcag atccagagca gtacgcctca cgatactttg ctgattttga agaagaagat
     2101 aaagtacttg cattgccaga aggtggtttt ttaaaagggg aagctaaaat tgtatctatg
     2161 gataatccag atataattca aggttcatat aattcagaaa ctgatcctgc ttcagtttca
     2221 gtgacagaag caaaaaaaat tgttgctgaa aaattcaaaa atgatattga aactactcca
     2281 attatgcctc gaggagcatt tccacccgat gttggtacta gcggacacct tcttgtacta
     2341 gcaggaggag gaagctataa atcacagcca tttagtggtg cgggatggcg ttttggaggt
     2401 atgggtgtaa aaccagctga tggtacaggc aactttttac gttggaaatc ctacattgac
     2461 gatggaagag taggaaatgt aaatcaagcc aacgcaacta aatctggttc tattcaagga
     2521 atggcattgt atgctcgtga aggattcaaa tactttgcac caaacgggcc tggttggaca
     2581 atgaatatag gtatttatta cacttataat cctgttgcag gtacgtatta tgttgttcaa
     2641 aatatttaat aaaacagcac aaagagattt ctttgtgctg ttttattatt tttagttgtt
     2701 gacaaacact aaaatataaa atataatcaa cacataaaca aacgtatgtt cggcaagaaa
     2761 gcaggggatt tttatggatg agatggtttt aagtactcag aaatggctaa acaagaaata
     2821 cagtaatgtt acagggtttg ataaggttcc agaaaatggg cgaacagggt ggcctacaat
     2881 ctatggactt attgaaggac tacaagtaga acttggtatt actaatctag tagctaattt
     2941 tggacctacc actgaaaaaa tgtacgataa tcaggttact cctaaatggg gcaaaaatct
     3001 acctaaaaat attgtatttc ttattcaagg tgccttttgg tgtaagggga ttaatccagg
     3061 tggcttcgat ggggtatata ctccatattt agatactgct gtaaaagagt tgcagactga
     3121 tgcagggttt aatggaagcg ctgtaactgg agttttggat gcgaaatggg ccaaagcgtt
     3181 atttgatatg agtgcttttg ttcttgttcc cggcggagat agtaaaatta gaaaaatgca
     3241 gcaatggtta aatgtaaatt atttagaata cacgggaata atgccttgtg atggtattta
     3301 tcaaagaaat tcaaatcaag cattaatttt tgcattacaa gctgaactag gatattctcc
     3361 cagtgaagca acagggtctt atggtaatgg gacaactagt aaaacttatc ctgtgtctga
     3421 aggtaactcg ggaaactatg taagaataat tcaatatgga ttatatgtta atggttattt
     3481 tgaagacggt acattcgatg gtattttcac taaatatatg ggtttagaag tactggcatt
     3541 ccgaaaattt atggtattgc ctgaatatac tgaaatagca gatgttgttg taataaaagg
     3601 actattgtct agcgctggag atattagaag atctgcagat ggcgcagata cttctacgca
     3661 attaactaga tctcaaatcc aaacattggt tgataatgat ataaaaatag ttggtagata
     3721 tcttactggt actgttggaa ttggaaaaga tgaacgaaat aagtatctaa ctacagagga
     3781 attgaataat attttttcta aaaatttatc tgtgtttcct atctatcaag atggaggtgc
     3841 agcattagct tattttactt atgatcgtgg cttatcagat ggtaagaagg ctatagatgc
     3901 agcaaaaaat ctaaatatac cattaacaac agttatttat tttgctgttg atctagacat
     3961 gttaggggaa gaaattcttg catatgctgg agaatatttt aagggggtat ctgctgtaat
     4021 gtcatatagc gggtatcaaa cgggtgttta cggaacaaga aatgtttgtt ctcaaataat
     4081 caataacggg tatgcttcgt ttgcatttgt ttcagatatg tcgactggtt atagtgggaa
     4141 tttaggtttt cctatgccta gacaatggtc ttttgatcaa tttgttgaat ttaccatagg
     4201 aagtggcaac ggagctgttg gtatcgattt aatcgctaca tcgggtagag atagcggatt
     4261 taatgagtta tcaaatgata ctaataatga taattacatt gccaaataca atcagaaggt
     4321 tataaatcag atggtacgtg cgtatcaata tctatcacaa gctggtcttg ataatccttg
     4381 gaaccctcat ttgacatttt atagatatgt aaattattct ggtttgtcat gggacatcat
     4441 ttcttctcct gtaacagagc atgatagaaa aatttatgat gaatatagga ataaattaac
     4501 taatagcgag ggcctgtata attattttat agatcctaat actggttcaa taataggttt
     4561 gcctcactta attgtgacgt tacaatcaca gatgtttcta gccgacacaa tcaatgatag
     4621 tgtttctgac tttgcaggtt ggttaggaga tttaatgact tgctggggtg aagttaagaa
     4681 attaggaata caaatggagc aaggtgtatt tgcattagta ggtacggctg caggtggaac
     4741 atttagtcta gaagatttat accaagatgt tgacgcggta aatgtttata ccttagcaaa
     4801 aagaaattct gattcaacag ctttatcggc tttaaaaacg tactattgtg ataagggtgc
     4861 tattgataga tttaatcaat ttgttaagaa cagatttggt tcttcagata aaatcgcttc
     4921 agtaacaaat agtttattag aaaatgacga aacagttgat atcttaggtg tagggataat
     4981 ttcatttttc attgataaaa tagttaataa ttcacttggg acagatttta cttatcttga
     5041 ttttattgga gatgagggga aagttgcaaa tggattttct gaaaaaatta ttcaatttca
     5101 agaaaataga agtaaactta attaagaatc gtttactatt taaacagtgt ccttttcctt
     5161 tttaaatata tacgataaaa taagtatatg aattgtaaaa ggacatgatg attatggaag
     5221 aaatagaatg gaataatctg actcaaaata ataaaaataa ttctggatgt ggaattatct
     5281 ttatgtttgt tatagttttg ggaatagtag tacttttaat aactgtcaag atagtagatt
     5341 actttgcgaa tactcctgaa gaacaaatac agagaaaact tcctgagttt gaaagagtac
     5401 caccttatga tccaagagat aattcatttc aagtaaaaaa attaaaagag tctccaaatg
     5461 aaatgtggtt tgaagttaca gttgaatcaa gcgacttcaa agaaaaaaag aaagaataca
     5521 attatattgt aaaggcaaaa gtatcaaaaa gatttatttt taaccctaaa ttagaaatat
     5581 atagtgttgt aatagaataa tagtgttaaa aaaattgtaa aagttaaaga agtcaaattc
     5641 tgatgtgaaa aataaaatat accatggaag acataaaaga aaaactggat aactagttta
     5701 tttaatggca gaccgttaag gcctgccatt tttatgtatt ttagcggaat aaatataatc
     5761 atgcgggagt gtaaacttac tgtttcaaaa agtatacttt ttgacatgcc ttgattttct
     5821 ttgtttatgt atggcataat aaccacataa tacaatttga aacgtttctg atttaatctg
     5881 attgttttga aacaatttta gtgaaaaaag ggtagataaa aacgatgaga aaattttttt
     5941 atatccgggt cagtagttat gatcaatcga tcgaacgaca actgatttcc gcgaaggaat
     6001 taggaatccc tgaagaatat atatttgtag aaaaagccag cggcaaagat tttaaacgcc
     6061 ctgaatatca attaatgaaa cggatgtttc gaaaaggaga tttactctat ctacaatcat
     6121 tagatagact aggcagaaat aaacaaatga ttttagaaga atggcgagaa ttaactaagg
     6181 aaaagcagat tgatatttct gtgttagaca tgcctctgtt agatactgct agttacaagc
     6241 aactagatgg gttagagacg cttatctctg acttaattct gcaattactc agctatatgg
     6301 ccgaagacga gcggaaacga attaatagcc ggcaaagaga aggcgtagaa gctgcgaaac
     6361 aaaagggtgt aaaattcggc agaaagaaaa ttgctttacc tcctgaattt cctgcgatct
     6421 attctgactg gaaagcagga aagataactg cagtctatgc tatggatcaa ttgggcatga
     6481 aacgaaatac cttttatcga cgggtgaaag aatatgaaca taccttgcac cacttttctt
     6541 gatagatata acagctatta gacgggaagg gagagtttga aaatggactt aacgaatcaa
     6601 agggtcgttt ttactggaac gctgcagcaa atgacacgaa cccaagccat cggtttggtt
     6661 cactctttaa acggccattg tcaatcaagt gttacttcaa aaacaaattt cctggtttgt
     6721 ggtcagtatt ctaagtcgtt gtttgatgat tctctctata caaaaaagga acaaaccgcg
     6781 cgggacttga ttgcgttagg tcatgagatt accattttat cagaagtcga attttatgcg
     6841 ttaattagtc aacagttgaa agaatggcaa cggtatttat aatcgttagt aaaatttaca
     6901 aggaggaaaa tttttatgaa gcgaaaatct tatgatcgtt ggggcattga aataactagt
     6961 tttaatcgaa atattgcttt tcacgtggag tgtgactgtg gggaattagc aaaaagtgtt
     7021 tatcaaaaaa attactttta ctgtcctaaa tgccatcgcc gatacggggt acatggaaca
     7081 tagaaacgaa atagtgcggt agaaaagcga atgaatgtag tatatttcta caaatcattc
     7141 gctttcttta ttttataaat agttggtcga gagatcccgt tttcttttgc aatctctgca
     7201 actggaatgc cttgctttaa catgtccacc acggttttaa aaactaagcg tttttgcgga
     7261 tctgttgagt taatagaata ctcgattggt cgtcccttat atcggccggc tttttgagcc
     7321 aataatactc cttgccgctg acgttcacga attttctcac gctcgttttg tgcaatataa
     7381 cttagcagtg ataaaaacat atcgaacata gcggtatcca ggagttcatt tccagtatta
     7441 aaatctaaaa actgtgcatc taatattttt aacgctactt ttttctgttt cataaaagca
     7501 actgtatttt ttatatcttc ataatctctt cctaaacgat ctagtgat
//
LOCUS       DBBGSZ010000072         7239 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.077, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000072 DBBGSZ010000000
VERSION     DBBGSZ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7239
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.077"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(31..1377)
                     /gene="gor"
                     /locus_tag="ACIZE5_002636"
     CDS             complement(31..1377)
                     /gene="gor"
                     /locus_tag="ACIZE5_002636"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HGC6109735.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(1511..2764)
                     /locus_tag="ACIZE5_002637"
     CDS             complement(1511..2764)
                     /locus_tag="ACIZE5_002637"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HGC6109736.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(2770..3693)
                     /locus_tag="ACIZE5_002638"
     CDS             complement(2770..3693)
                     /locus_tag="ACIZE5_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HGC6109737.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(3914..6406)
                     /locus_tag="ACIZE5_002639"
     CDS             complement(3914..6406)
                     /locus_tag="ACIZE5_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGC6109738.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(6413..6880)
                     /locus_tag="ACIZE5_002640"
     CDS             complement(6413..6880)
                     /locus_tag="ACIZE5_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HGC6109739.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(7016..7089)
                     /locus_tag="ACIZE5_002641"
     tRNA            complement(7016..7089)
                     /locus_tag="ACIZE5_002641"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7053..7055),aa:Arg,seq:acg)
     gene            complement(7147..7220)
                     /locus_tag="ACIZE5_002642"
     tRNA            complement(7147..7220)
                     /locus_tag="ACIZE5_002642"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7184..7186),aa:Pro,seq:tgg)
BASE COUNT         1997 a         1598 c         1177 g         2467 t
ORIGIN      
        1 taaaaagctg ttggaactgt taatattaaa ttatcgcatc gttacgaatt cttccgctcc
       61 tgttggatgg atggctactg tattgtcaaa gtcttcttta gttgcaccca tcttgatagc
      121 cacggcaaaa ccttgcagca tctcatcgac accaacacca atagcatgta agccgacgat
      181 tctttcttct tttccgacac agatcaattt catttcgcat ttttggcgat aatcatttaa
      241 tgcaaagtac attggggtaa agcgtgaacg ataaactttc aattcatttt cgccatattt
      301 ttccaatgct tcttcttctg tcaaaccaat tgttgcaatt ggtggatgcg taaagacgac
      361 tgtcggaaca agtttatagt caagataaga atctttcttt ccattaaata aacgttctga
      421 taaacgtcta ccagctgcga ttgcaacagg agtcagatct aatttaccga tcacatcacc
      481 aacagcaaaa atatgttcat ccgttgtatt ttggtattta tctactttga taaacccttt
      541 tttgtccaat tccacatttg tattttccag acctaatttt tcggtattcg gtacacgtcc
      601 accggcaaaa agtacacaat caccagttaa ggtttcacca ttttcaaata gcaccgtata
      661 ttcgtcattg tttttagtaa tttctttagc aatatgatgt gcgtaagttt ttattccagc
      721 ttcttggtac atttggatca aattgtccga aagcatttta tcaaacgttc taagtggtcg
      781 ttcttttcga tatgcccaca tgacttcact acctaaacca cgaaatacac ctgaaagttc
      841 agccgcaatg tatccagcac ctaaaacgat tgctctctta ggtaactctg ttaattcaaa
      901 aaatccattt gaatcaattg cgtattctcc accaggaatg gtcattttac ttgcacggcc
      961 tccagtagcg atcaagattt taggagcacg ataggtttca ccgtttactt cgatcgtttg
     1021 actatcgata aaagtagcgt aaccttttat agcctcgaca tgattgctat ctaatcctct
     1081 ttgataagca ccgtgtagaa aatcaatata tttttctcgt ctttctacta gaccggcgaa
     1141 atcaacattt tttaaatctg cttggatacc gtaacttgag gcatctcgtt caattgtttc
     1201 caaaatcgta cttgcttgcc acataacttt tttaggtaca caaccgacgt tgacacatgt
     1261 tccgcccaat tcattcgctt caatcagcaa aacttttgcg ccatgcatcc ctgctctgtt
     1321 tgctgaagca ataccgccag agccgccacc aattacgatg taatcatata tttgcatttt
     1381 gttcctcctt attgaagaga tcaatcaaaa cctttattta acgatccttt ttctacagaa
     1441 aacaagtgta acacttttct tgaattttgt atgcgaagat gcttaaaaca gggatatatc
     1501 agctttttcc ttatttacgt tttcggatca tatctccagg tttcaccggc tgtgcgactg
     1561 gcatagttaa aatcatcatt ggatttggtg ctcggtcaat ggattcgcct tcttcattat
     1621 gcataacttc aacggtttga ctgaaatgac tgaatcctgg accataaaat tcgatttcat
     1681 ctcctacaga aaacaagttt ctctgacgta tcgtagcaat ctgtgttgcc tcatcataag
     1741 ataatacttc accgacaaat ttatatactg ggattttacg acgttcaccg aataattgtt
     1801 cgttttcagt tggtgtattg tagtaaaaac ctgtagctaa ttctcgttgt gctactttcc
     1861 ataactcgtc gatccattct tgcttgcaga catagttttc aggatcttcc atataactgt
     1921 ctacagccgc tttatagaca tttgacaccg tagatacata atggatcgat ttcattcttc
     1981 cttcgatctt gaagctgtct acgccgtttt caatcaattc tggaatatgt tcgatcattg
     2041 acatatccac tgcactcatc gagaattctt cttccacttc gcctgtatca gttaaactgt
     2101 ttcgttcttg accaaaaggc atatcgaaca atccatactt ccagcgacaa gattgagaac
     2161 atccgccacg gtttgcatcc cgcatcgaca tatggttgga caatgtgcat cgaccagaat
     2221 aagagataca catggcacca tggataaatg cttcgatttc ggtatccgta tttttacgaa
     2281 tctctgccac ttcctccatt gaaacttcac gagctaaaac gacacgttcc aacccttctt
     2341 ctttccagaa ttccaatgtc tcaaaattag ttgctgaagc ttgagtggat aaatggatcg
     2401 gcagacctgg ggcttctgtc gcacaaattt cgatcaaagc tggatcagaa acaatcactg
     2461 cagaaatacc gacatcacgc aaactgcgga aaaattcccc tgctccatct tcatttcctt
     2521 catgggtgac catattagca gcaacgtata ccttcgcatc atgttctttt gcaaaagcaa
     2581 ctccttcagc catttcttca taagtaaaat tacctgcacg gcttcttaaa ccatatgcat
     2641 tcccgccaat atatactgca tctgctccat aatggatcgc ggtttttaac ttttccagtg
     2701 ttcctgctgg cgctaggatt tctggtcgtt tcaattttct ttttactgtc atttctttca
     2761 tcatactcct tatttgatag cagaaggatc aatataaaag aatcctgtat ctaattcacg
     2821 gttttcagga tgcaatttac tgatttcgct agtcattttt tccgcttttt cttgatccca
     2881 gctaccttct aaaatttgtt tttttgcttc ggcgaatagt cgagtgatgt ttacgaattt
     2941 ttcgcctgga gtaaataatc cgtccaattt ccatgtacag taatgatgct gataaagttc
     3001 attcaattca ttcgagagat tcagatcatt gctggcaaaa atatgtgtgc catgactatc
     3061 ttcataaata gaataatgtg tctcttcttt tttaggttcc gagataaaaa gacctctttc
     3121 acgatctttt tgttcgtctt gtttcgtata gttatagtaa ttctgtagca gtggacgttt
     3181 ggattgatgg atgcatgtag caccatacac aagggtttct acaggaatat cgagtttttc
     3241 ttccatcgcc ttcatctctt caaaaggaac ttcacgagca agtactgctc caactgcgcc
     3301 ttttttcgcc cagaaattga tttgacgtgc gctcgttact aatgtttcag catcataaat
     3361 atacggtata cgcaattcag gatttttttt catcgtataa ataatacctg tatcaccaac
     3421 tgtgatcaca tctacgttta tttcttttaa aaaagccaaa tattcaggta catttttcat
     3481 tttttcagga tgaatgatcc catttacagc aatattcgct tttttaccat acttgtgtgc
     3541 taattctacc aattgtcgct gttcttctcg tgtaaatgaa gcaggcagac gcaatccaaa
     3601 ttgctcttca ccgaaatata gtgtatctgc acctgcagca agcaactgtt ctgcttgttc
     3661 aatagtttct actgtggtta tgagttcgat cataattttc tcctcctaca acttcataat
     3721 agtagcatag ctctaaaaac tttccaatac ttcttctatt taaagtcgga tttttgaaaa
     3781 ttatttcaca aaaaatcaaa ataaagttcg atatattctg tccaaatata aaaagagatt
     3841 gtgacaaaaa tcttgtcaca acctcttaat caagtcttac tattataaaa attcagctac
     3901 acaggccaag taactatagg gaacctactg tttccttttt aggtccgcga acattcaatg
     3961 tgatcttacc ttttgaagca cctactgtta cgtggtcacc taaacgaatt tctccgccaa
     4021 gcaaagcctc gctcaatcga tcttcaattt ctttttgaag tgcgcgacgg attggacgtg
     4081 caccatattc aggatcaaat ccagctttcc cgatcacatc gattgcagat ggtgtgattt
     4141 tcacttgaat atcttgttct ttcaatcgtt tgataatcgc tttgctcatg atttggacga
     4201 ttgtatggat ttcatcttta ctcaatgaat ggaagacgac agtctcatcg attcgattca
     4261 agaattcagg tcggaaagct ttctttaact cttctaagat acgtttttgc atggctttgt
     4321 gatctttagt aacatcttgg acattgaatc cgacattttt ttcttctcga atttgtgtcg
     4381 ctccgatatt tgaagtcata atcatgattg tatttctaaa gtccactttt ctacctttag
     4441 aatctgttaa atgaccatca tccaatactt gcagaagtaa attgaaaacg tctggatgtg
     4501 ctttctccac ttcatctaag agaatcactg aatatggttt ttgacgaatt ttttctgtca
     4561 actgtccacc ttcatcatac cctacgtatc ctggaggaga cccgattaat cggcttgtac
     4621 tgtatttttc cataaattct gacatatcaa cacggatcag ggcatcttca cttccaaaca
     4681 tgacttctga aagtgctttg gccaattctg tttttccgac accagttggt ccaaggaaca
     4741 tgaatgaacc aattggacga tcaggatctt tcaatccgct tcgtgcacgg cggatcgcac
     4801 gtgaaactgc tttgacagcc tcatcttgac caacgacacg ttcatgcaga agtccttcca
     4861 gttctaacaa gcgttcgctt tcttttttct ccaactgctg tagagggaca ccagtccact
     4921 ccgatacaac tgtagcaaca tcttcttctg ttacacgatc agaataacct tgctcctgtt
     4981 ttgcttcaat tgcagaaact ttttgcagct ttttacgtag tgctttttct tgtctgcgta
     5041 attgagcagc attttcaaag tcttgttttt ggatcgctgc ttccttttct tgtactagtt
     5101 catcgatttc tagtttgatc acagttgatt ttgttaagtg atcggtttga tccaaacgga
     5161 ctttcgctgc tgattcatcg atcaaatcaa ttgctttatc gggtagttga cgagaagtga
     5221 tataacgaac agaaagattg actgctgctc gtacagcttc atctgtgatc tccactccat
     5281 ggtgctcttc atatcttgta cgtaatcctt gaagaatcac ttctgcttct tcaggagttg
     5341 gctcatctac ttgaatgcga gcaaaacgtc gctctaatgc agaatctttt tcgatatatt
     5401 tttgatattc atctagggtc gttgctccga tcgtttgtaa ttctcctcga gctaacgccg
     5461 gtttcaagat attcgaagca tcaattgctc cttctgctcc acctgcacca attaaggtat
     5521 gcaattcatc aatgaataag attacttgac catcattata gatttcgtcg atgacctttt
     5581 tcattcgatc ttcaaattca ccgcgatatt tcgtaccagc aaccaaagat cccatatcaa
     5641 gcatcatcag gcgcttttct tgcatgtctt ctggcacttc acctaaaatg attttttgag
     5701 ctaacccttc agcaatggct gttttgccta caccaggttc acccaccagt acagggttat
     5761 tctttgtccg tcggctaaga atctggataa gccgtttcac ttctctcgaa cgaccaacaa
     5821 ctgggtccag cttgttttct tttgctaatt tcgtcaaatc acgtgctaat gaatctagcg
     5881 taggtgttcc ttgcggtgtt tgccgtttat cttgtacatt tacatttcta cgacgattca
     5941 ttccttttcc agcagaatca ccagctagcc ccattttttg tttcagaact tgacgggctt
     6001 ttgaaaggct gatacctaag ttgatcatga ttcgagtagc catgatactt tcatctttta
     6061 ataagctcat caaaatatgt tctgttccaa ctttttgaga accagttttc ttcacttcgc
     6121 tgctagctaa agcaaaaact tgtttcattc ttggtgaata tggaagaaag actcctttag
     6181 ggtaagaacg gataccacca taaccaatca gatgttcaat ttcttcataa atttccgttt
     6241 cattcaaatc catttcacgt aatacttttc cagcaattcc attttgctcg accactaagg
     6301 ctagtaaaac atgttctgaa ctaactgatt gatgtttcaa ccgttttgct tcttcttgtg
     6361 caatttctaa tactgcttgg gctctttcag taaaaagttc ttccatctaa tctcacttcc
     6421 catcttcata acttaaacgt tccagaaatg ctcggagaat ccgagcacgt gtatgatctt
     6481 catattcatt gaaattcaat gtgttttttg caattgcact caacatcaag tttccttctt
     6541 tttttgtaat tatttggtct tcataaagtt tttgaataat agcaaaagca tttttctcac
     6601 tgattgtatc atcaaataac tgatttatct gctcaagtaa ttgtttttta tctgaaatcc
     6661 ttacttttgc aattcgtata taaccaccac caccacgttt gctttctact agataaccac
     6721 gttggatggt aaaacgggta ttaatcacat agttgatttg tgaaggaaca cagttaaaga
     6781 ggtctgccat ttcaatcctt cgaatctcga tcatttcact attttccaga attttcttta
     6841 tatatgattc aattaaatcc gaggtattct gatgtgccat cttattcatt ccctttgact
     6901 aatattgacc ttaattataa cgaatttgat aatagaaaga aagaagaacg ctttttgtta
     6961 aataaatcct ttagaatcaa caaaaaaaaa tacggaatat actattccgt atcgacgcgc
     7021 ccaagaggag tcgaacccct aaccttttga tccgtagtca aacactctat ccagttgagc
     7081 tatgggcgca tattcaattt aaaaaaatta taaatcattt gaaaacaaaa agcaagataa
     7141 aaaaaatcgg gaagacagga ttcgaacctg cgaccccttg gtcccaaacc aagtgctcta
     7201 ccaagctgag ctacttcccg tttaaaaaat aaaaaagac
//
LOCUS       DBBGSZ010000073         7140 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.078, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000073 DBBGSZ010000000
VERSION     DBBGSZ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7140
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.078"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..616
                     /locus_tag="ACIZE5_002643"
     CDS             <1..616
                     /locus_tag="ACIZE5_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HGC6109740.1"
                     /translation="FVFAPLEGEDLASFLVGAAIMMIGMTLFLFGADYSMMEVGDLVG
                     KYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQQVYDISDGEIGRVLLIGIVSVGT
                     GVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFTSSEFMPIAFDSGGVTTGPVTVPF
                     ILALAGGMTSMIKQKKNENDSFGMVGIASLGPILAVMILGVIFQ"
     gene            613..1386
                     /locus_tag="ACIZE5_002644"
     CDS             613..1386
                     /locus_tag="ACIZE5_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HGC6109741.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            1383..1781
                     /locus_tag="ACIZE5_002645"
     CDS             1383..1781
                     /locus_tag="ACIZE5_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HGC6109742.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            1966..2637
                     /locus_tag="ACIZE5_002646"
     CDS             1966..2637
                     /locus_tag="ACIZE5_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109743.1"
                     /translation="MNFLVVLKDTLIERFTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            2696..3136
                     /locus_tag="ACIZE5_002647"
     CDS             2696..3136
                     /locus_tag="ACIZE5_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109744.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            3148..3816
                     /locus_tag="ACIZE5_002648"
     CDS             3148..3816
                     /locus_tag="ACIZE5_002648"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HGC6109745.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            3880..4503
                     /locus_tag="ACIZE5_002649"
     CDS             3880..4503
                     /locus_tag="ACIZE5_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HGC6109746.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            4559..4945
                     /locus_tag="ACIZE5_002650"
     CDS             4559..4945
                     /locus_tag="ACIZE5_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HGC6109747.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            5158..6549
                     /locus_tag="ACIZE5_002651"
     CDS             5158..6549
                     /locus_tag="ACIZE5_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HGC6109748.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
BASE COUNT         2276 a         1160 c         1573 g         2131 t
ORIGIN      
        1 gtttgttttt gcaccgttag aaggagaaga cctcgcttca tttctggttg gtgcggcaat
       61 catgatgatc ggaatgacgc tctttttgtt tggagcagat tattctatga tggaagtcgg
      121 agatctagta gggaaatata tgatcaaaaa gaaaagtttg accgttttgg tcagtttggg
      181 atttgctatc gggatcgtga tcacgattgc tgaaccttcc gtgcaagttt tgggacaaca
      241 agtatatgat atatctgacg gagagattgg cagagtgttg ctgattggga tcgtcagcgt
      301 cggcactgga gtatttctag cctttgcgct gcttcgggtc gtattcaagc tatcctatta
      361 tcaattgatg gctataggct acataggcgt tttgatcgcc tcatttttca ccagttccga
      421 atttatgccg attgcttttg attcgggggg agtgactact ggtccagtaa ctgttccatt
      481 tatcttggcc cttgccggag ggatgactag tatgatcaaa caaaagaaaa atgaaaatga
      541 cagttttgga atggtcggta ttgcttcgtt agggccgatt cttgccgtga tgattttggg
      601 ggtgatcttc caatgagttt ctggcagcaa gtgatagatg gaatcgaaat cgttaccatg
      661 gaagtcattt tggcagtggc acctatcgta atcctatttg ttttaatgaa tatcattagt
      721 tttcgtatgc gcaaaaagcg tttctttgac attatgaaag gtttcttgat aacgactatt
      781 gggttgatcc ttttcctgca cggagtcaat atggcttatg taccggtagg acagcattta
      841 ggcagtgcta ttgcgggatt gccttacaat tatatactgg ttccccttgg ctttttaatg
      901 gggttcttag tagggtttgc tgagccggcg attcatgtaa tgatcaaaca ggttgaagaa
      961 ttgagcgagg ggagaatccg atcgaaaatc atgctgatgg taatttcaat tgggatcggc
     1021 gcagcagtag gattgtctat gtggcgtttg ctcgtcggat tctctcttta ttatttcttg
     1081 atcccaggat acgggctagc atttatttta ggacgaaaag tggacaagat ctttttagca
     1141 atggcttttg ataacggtgg agtagcaacg ggcccgatgt gttcgacatt tattttatca
     1201 atgagcgtgg caatcgctgc acaaattgaa ggaagagatc cgatcattga cgggtttggt
     1261 gtggttgcaa tgattgcatt gacaccaata ttatccactt tagtactagg atatatttat
     1321 aaacgaaaag atgaaaaaga cagaatcgaa aaagaaagat tgcaaaaatt gggggaaagc
     1381 aaatgaaaga tcttgtagca ttgaatcttc acatgattgt gacgatcgtt gacggaggaa
     1441 tgggcgaaga tgttatcgac ttttcaaaag aagcaggtgc agcaggcgga acgatcttac
     1501 atggaagagg ttctggtgta catgattcag ggaaattttt aggtttggac atttcgccag
     1561 aaaaagatat tgtgttgaca ttagtacccg atagtttgac gaataaagta atggatgcga
     1621 ttggtcaagg catcaacatc gatattccag gtaatggtat ttgttttagt attgatgtag
     1681 acaaagtcat tggtatcact aagattcatc aatatcgaga aattatcgga atgcaagaac
     1741 ttttagatga aaataacgat agagaaaagt ctgaatcata gacaagcgtt tgaagaggaa
     1801 ataaacacaa acaagaaggc ggatgagcgt tatttccgct tttttgtttg tatttttctc
     1861 gtgaatactt atgaaatagt aaatttttat gaaattctac tctaagcatc agactttctt
     1921 ttcaaaatat gctattttaa aaatgatgaa aaaaggggga gaaaaatgaa ttttttagtt
     1981 gttttaaaag atactctgat tgagcgattt acatttctat atgttcaatt gcaggaaaat
     2041 aaaacattgc tgcatttttc accagagttc catctagagg ggctaacatt aggagaaatc
     2101 tatcaagcag aagggctgtc ggctgttttg cactttttta aggtagaatt ggaattacca
     2161 gtaaaagatt atatcgagct ttctcttgaa tcttgggatc gagcagtggt tgaactgttt
     2221 ccagaaggtt taatgatcga tacaaacgat gggaagatcc atctgactgc agcagaactg
     2281 caaaaacaaa tgcgttatca aatagatgac gaaaattctt tttctatttt tagacgtcag
     2341 caaaagattc taaaaagctt tttaaaagtg atcagtaaaa aacggaatct gatcaaaacg
     2401 acacagctgt tgaaaaaata tccaggtctg cttcacacgt ctattcaatt tcctcaattg
     2461 attacgatga tccatcgttt tatacgtatg caacagctac catctaagaa gctgtttctt
     2521 ccattgacgg acacatttcg agtagtcaac agagaagata aaaagaaagt gattgtgatt
     2581 gactttacca gaaatcggaa tgtccttcac caagttgcaa tggaaaaggc caattaaggc
     2641 tttttctttt tggatttttt tgtcataata aatattagat gatggaggag ataatatgat
     2701 gcaaacatgg ttagaaaggc taatacgatt tcagcagaac tatcacaaac ttatgcaggg
     2761 aagatatgcg aaatttgatc agttgaatcg cggtctattg atcgctgcgc ttgtctttag
     2821 tttgctaagt cgttggttgc cctatagaat cggacaattg ttgttcatcg tctttttcgg
     2881 atggatgata tttcgtttcc tatcaaaaaa aatctacccc agactaaatg agaatcaacg
     2941 ttatttgaaa tatcttgata gagtcaaaga aaaatatcat cagataaaaa acaaaaagca
     3001 agtcaaaatg gatcgaaaaa gttatacttt ttttgagtgc ccgaattgtc atcaaaagca
     3061 gcgtgcacct aaaggaaaag gacgaatacg tgtgacatgc aaaacatgtg gtataaaatt
     3121 cgaaacgaat gtttaaggga gaaaagaatg aaattagtat tattacgtca tggcgaaagc
     3181 gaagcaaatt ttgaaaatta ctggacagga tggctagatg tcgccttaac agaaaaagga
     3241 aaagaacaag cagcagttgc cggtcaaaaa atgcttgaag ccggacttca attcgatgcc
     3301 gtttatacct ctgttttgaa acgtgcgatt cttaccggac aagtcgcact agaagaaatg
     3361 ggtcagttat ggcttcctat aataaaaaca tggcgtctaa atgaacggca ttatggggat
     3421 cttgtgggta aaaacaaaga taagatgaaa gaaatatacg gaaaagatca agtaaaaaca
     3481 tggcgcagag gatatacgga agttccgccg ttaaccgcag aaaatagatt tgaccgcaga
     3541 tatgatcact tggatccgca tttgatccca tacggagaaa gtctggaaat gacagtgaat
     3601 cggatcattc ccttatggca agatcatcta gcaccaaaac taaaagatcg gcaagattta
     3661 ctagttgtgg gtcatggtaa tagcatccga gcactgacaa aatatttaga agatgttcct
     3721 gaagatcaaa tggatacgat cgatatccca aatgcacaac caatccagta tacattagca
     3781 gatgatttga caattctgga caaaaaaata ctttaaagaa cacctttatc taaaagtgag
     3841 agatagaaaa aagaagcaaa ggaatggaac aaaaggaaca tgaaaaatta tatatgggac
     3901 tttgatggta cattgtttga tacgtatccc gcaatggtag atggtgcatg gcaagcacta
     3961 aaagattttg gtatcagtat ggacaaaaaa gaaatctact tcaaaatgaa aaagtattct
     4021 actagttatt tgatcaatga atcaaacttg aatgccagag agtttaatga attatttcac
     4081 cgatatgaaa aagaaagtac ggaagtttcc cgtccatttc cagaaacgaa acaagtactg
     4141 gaaatgctaa aagacaacgg cggtcgtcat ttcatcctga cccaccgttt gacagaatca
     4201 acatggggcc tgttaaaaga acatcgattg gcacatctga ttgaggaagt agtagggatc
     4261 gatcaggact ttcctcgtaa acctgatcca gcatctttaa attatttgat cgatactttt
     4321 catttagaaa gaacagacac gatgatgatc ggcgatcgtc gtttagatat cgaagcaggg
     4381 aaaaatgcag gagtcgctac ttgtctttac gacatcgatc attttctggg tgagatcccg
     4441 gcagattatg tggtaggaaa tctgaatgaa atccttacct tgcagagcat cattaaaaag
     4501 tagtatcccc tttcaaagga gatatgttat aattttcata aaggagtgat aaaattatat
     4561 ggaaatcaga agacaaaaag aagttgtaga agcatttcat tatgatatga gattgccgaa
     4621 ccaagaagta gaaacagatt tgaaagtagg cttctcgcct ttaaaagaaa cgatcgaaaa
     4681 ctatccgaaa gaacatagca tcgtaggagc acgcttagag ttccgtttag tgtttgatac
     4741 atatgtttta tctggaagtg tgagtcagat caatcatatc ctcaatcgga aaattgaagg
     4801 tcaaaatgat gtcacacaag aagaagtgga cgagctagta gcaccgttat tcgatatcgt
     4861 acgccgaatg tcttatgagg tgacagagat cgccttagat cagcctgggg taaaattgaa
     4921 ttttcaatca gaaaaacaag aatagacagt aaaaacatac ctgcgataga ttaaagctat
     4981 cacaggtatg tttttttatt actaattgta agcaaaaaga atgtcatttc gataaaaatc
     5041 gtctaaaata taaaagtcac tgaaaaaaat tttttcagga ggatggttga agaatcattc
     5101 tcgggaacct ttacttcctt cgatggactt gtcattaata atatgaggag gagaaaaatg
     5161 acaacactca tcacagtttt agtggttcta gtttttgcgg cattattata tgtgttctat
     5221 cgtatgcaaa agcgccatac aaaattttca acacgcgtct ttacagcatt aggagttggt
     5281 atcgtctttg gcggtctgct tcaattgatc tttggtgtag acgacaaagt cgttactcaa
     5341 tcaatggaat ggatcgggat tgtaggtcaa ggatatgtat cattcttgca aatgctagtt
     5401 atgcctttag tgtttatttc gatcattggt gcattcacaa aaatgaaagt ttctgaaaag
     5461 ctagggaaaa ttagtgcgac tgtattgact tctttacttg gaacaacagc tattgcagca
     5521 ttgatcggaa ttggttcaac aatgctgttc ggactccaag gagctaaatt cacacaagga
     5581 gctgcagaaa cagcacgaat ctctgaactg gcaacacgtc aggaaacagt tgaaaactta
     5641 tcgattccac agcagatttt atcctttatc cctaaaaacg tttttgctga tttagcaggt
     5701 agtcgtgcaa caagtacgat tggagtcgtt attttcgcgg catttgtcgg aatcgcttat
     5761 ctaggcgtga aaagaaaagc gccaaaagaa gcagcattct tttcagattt agtcgacagt
     5821 ctgtataaaa tcattatgcg gatcgtgacg cttgttttgc gtttgacacc ttatggagta
     5881 tttgctttga tgacaaacgt tttggcaaca agtgattttg cagctatcgt caatttaggt
     5941 aaatttgtcg ttgcttctta cgtagcattg cttgctgttt tgattgtcca ctcactgatt
     6001 ttgattggtg caaaagtcaa tccaatcaac tatttcaaaa aagcctttcc ggtattgagc
     6061 tttgcgttta cttcacgttc aagtgctgga gctttgccat tgaatatcga gactcagaca
     6121 aaagctttag gagtagatga tgcaacagct aatttctcag caagttttgg tttgtctatt
     6181 ggacaaaacg gctgtgctgg cgtttatcca gctatgttgg caacgatcgt cgcaccagca
     6241 gctggagtga atgtctttag tttggaattt attttgatgc ttgtggcaat tgtaacaatc
     6301 agttcttttg gtgtagctgg agtcggtggg ggcgcaacat ttgcttcact gatcgtttta
     6361 ggggcaatga acttgccagt agcaatcgtt gggttagtta tctctgttga accattaatc
     6421 gatatggcac gtacagcagt aaacgtcagc ggtagcatgg tagctggtat cgtgacaagt
     6481 gcacgcatca aagatttaga tcgcgatgtc atcaatgatg attctaaagt gatcgatgtg
     6541 aatgcatagt caaaaagagg ttgtgataga agtggtcagc tttaagaaat aagaagaagt
     6601 ttcctaaaaa tagtttctca aatttttgtg aaatttcggc ttatttccga gaagctactt
     6661 ctgaaacacc gtgaataaga ggttgtgaaa aagctgccct gcatcaagta ataagaacag
     6721 ccaaacaaaa atagttcctc atattttacg tttggttgag cttattaccg cagatgcaag
     6781 cttttgaaca ccgtttaaga aagaggtcgt gagcctgccg tttcactctg agtcacaaag
     6841 agcaatttca aaaaatagct tctcatgttt gttgaatatt gtgtcttgtg accgaggagt
     6901 tgtcaggaga acaccgttta ccagaggttg tgacttgttt ttagtcacga cctctttttt
     6961 tatttattcc atataaatac acattattta ttccgaaaag tgaaagcgca aataacaaaa
     7021 acaaccaact tatttattat taaagaaaag cgtatttaag taggacgatt ctgttgagag
     7081 ctttcgtaga ttttcccatt ttcctatggt aaactgacaa agttgagaat gttagaacag
//
LOCUS       DBBGSZ010000074         6999 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.079, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000074 DBBGSZ010000000
VERSION     DBBGSZ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6999
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.079"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            252..677
                     /locus_tag="ACIZE5_002652"
     CDS             252..677
                     /locus_tag="ACIZE5_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGC6109749.1"
                     /translation="MHLHRISALAVQIGRYHHSETRAVMEGLEEAIQTTNDCPYRRTF
                     HSDQGWAYQMKAYRNKLKEYKIFQSLSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCF
                     EELKSAIDSYIYYYNNERIKQKLNCQSPVQFRKTTVTVV"
     gene            complement(982..1944)
                     /locus_tag="ACIZE5_002653"
     CDS             complement(982..1944)
                     /locus_tag="ACIZE5_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6109750.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGESI"
     gene            complement(1946..3385)
                     /locus_tag="ACIZE5_002654"
     CDS             complement(1946..3385)
                     /locus_tag="ACIZE5_002654"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HGC6109751.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            3570..5516
                     /locus_tag="ACIZE5_002655"
     CDS             3570..5516
                     /locus_tag="ACIZE5_002655"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HGC6109752.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5780..6652
                     /gene="scrK"
                     /locus_tag="ACIZE5_002656"
     CDS             5780..6652
                     /gene="scrK"
                     /locus_tag="ACIZE5_002656"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HGC6109753.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         2228 a         1211 c         1249 g         2311 t
ORIGIN      
        1 attataaata actcataaaa aatattttga ctttcaaaat cacttttgct accagaagtt
       61 gaggcgaagt gttttaagca tagttgtacc ctagtttgac cgttaaaaat aaataacgat
      121 cgctagagtg caactatgtt tgtttgctct accgtcagcg tcggcttggc ctctcacatc
      181 cattaccgtc gggatcatct ccgttacata cccttacaaa atacgccctg taagcattgc
      241 atgaaaccac cgtgcatttg caccgtattt ccgccctagc cgttcaaatc ggtcgctacc
      301 accattcaga aacacgtgcg gtaatggaag gtttggagga agctatccag accactaacg
      361 attgtcccta tcgtcgtacg tttcactcag atcaaggttg ggcgtatcaa atgaaagctt
      421 atagaaacaa attgaaggag tacaaaatct ttcaaagcct gtctcggaaa gggaactgct
      481 tagataattc acttatggag aatttttttg gcttattaaa acaagagatt tttcacggga
      541 aagtttataa ctgtttcgag gaattaaaat cagccatcga tagctatatc tattactaca
      601 ataatgaacg gataaaacag aaattaaact gtcaaagtcc cgtccaattt cgtaaaacaa
      661 ccgttacggt tgtgtaaaaa tatcatttta gagcatgaaa aaaggagtgg atttctccac
      721 tccaaaaaag tctaactttt gggggtcact acatttttga tcctttttat ttgattaatt
      781 atatccagct ggataataat tttgggggca acatttctat cttactatta tcttcctaaa
      841 gtagtagact ttcttattgg gaaaaattac aacaaaaagg agtggcttag ttgacaactc
      901 ctttttgttt acaaatcaat tggatatcta caaattgtat tttctaacgg attttataga
      961 cattaaaaaa ttaatttgac gttaaatact ttctccagaa agtattgaga ttggtaaaat
     1021 ataatcctta tttgtctttt cgcctttaat ttttttcaga agaatatcaa caataagact
     1081 tgcaatttca tcaattggtt gtcttattgt tgtcaattgt gggaaaaatt tctcaatgaa
     1141 agaggtacca tcgtatccaa taatttttaa atcttctggg atattaagtt taagttgatg
     1201 agcaattttc atagtgagaa tggctgttaa atcatcagaa acaaaaatac catctggttt
     1261 gtgatttata atagttgact ttatttccat ttcacgacgg atagtagaca gattattagg
     1321 aattttgaaa atttttccat ttggattttg aaaagaaaaa cctagtgcac gtaattctgt
     1381 gggagaatcc gtgttatcat ttcctgtaat cataatggta ttttgacaac catttttttg
     1441 taaagtctta gctgcaagtt ttcccccttc aaagttatct gaagaaacaa tggaaacatt
     1501 aggagctaaa tttctatcaa aagcaacaat aggtgctctc acacgctcat aatcagcaat
     1561 tccaagatta tggcttgatg agattatgcc atcaacttgg ttggcttcaa gcatttcaat
     1621 gtattctctc tctttagcag gatcattttg actattgcaa ataatcgttt tatatccatg
     1681 tttaaataac tctatttcga gatactcaat gagttcagag taaaagatat tactaatatt
     1741 aggaaaaata agaccaataa gctgaggtga ctttccttga agtccacgtg ctaaattatt
     1801 tggtttataa ccaagagttt tcatagcttc atgaactttt tgttttgttt tttctgataa
     1861 atatccctta ttattaatga cgcgtgaaac ggttgttggg ctaactccag ctaattcagc
     1921 gacatcagtt aattttgcta ccattttaat attttaattc aaagtatttt ccagtaggtt
     1981 cgcctgattt gatttgaata ccattttggt gattttcagg gaatacacga ctagtaaaca
     2041 ctttttctcc tttattaata aaaatctcaa tgattgagtt atctacaaaa atgttagcag
     2101 ttgtttcttt agtatcaatt gagcattcac gaatcgtacc aaagtcagtg gcatattgaa
     2161 tgcctgcttt gctgcgatct aaaataattt ttccttcttt ggtatctaca atcaagctaa
     2221 gtccatttcc tttactatca gagaaaagaa gtaactccga tttctgattt ggaggaaaag
     2281 ttagttcaag ctcataagta ttatttgttt ctgcttttgc tgtaaattgt tcagaactag
     2341 cacgtaatga tgtaatagct tctactggat attggtaaag tttaccatct tttattgaaa
     2401 gttcttttac aagactcatt gctccctgat aatcatactt atcagttgga taatcgatat
     2461 caggtagtcc aatccaactg acaatcagag cacgaccatc aggagtattg aatccttgag
     2521 tcgcatacgc ttcaaatcca taatcaagat tttgaatttc tgaagcgccc acaagtttta
     2581 ctttttctat gtcaagcgat tgacagatct taaaagtatt cggatagata ttcccataat
     2641 ttagctcaga tttatccaac ccttgaggac aataaatgag aacaggtttt ttgtctacaa
     2701 atactagatt tggacactca atcatgtatt ctgaaccagt gccgccaaaa tcaaggttgc
     2761 caacttcctc ccatgtttcc acgttattgt catccgcttt gtaaagtttg ataaagcctg
     2821 atttttctaa attttgtgct ccaacaatcg catacaattg tccttcataa ttaaacattt
     2881 gtggatcacg aaaatgatca gttacatcag caggtttatg aataagaaca ttctcacctt
     2941 tcgtaatgtt gtagtcttta tccatccatg ctccgatttg aagtgtatca cgttcccaat
     3001 tttcatttcg aacgtttcct gtatagagta agaatagatt cccctctatt tcatatgcag
     3061 aaccggaata agcgccgtgg ctatctcgtt ttgtgtctgg aagaagttct gctcctgtta
     3121 catgaaaatg aactaaatca tctgattcat tgtgtaccca ttctttcaac ccatgagcag
     3181 ctccaaatgg ccaattttga taaaaaagcg tatattttcc gttaaaaaaa gaaaaaccat
     3241 taggatcgtt taacaatcct gttttaggtt cgatatgata gctagcacgc caaggtgatc
     3301 gttttacatt atccttaatt ttatccatct catctttagt ccaatcagaa taagcacgat
     3361 atcgtatttc tcgaggtaag ttcatatttt actccttcaa tttatctttt tacaactagt
     3421 atggtaaacg ttttccgttg aaaaatcaat catttcattt aaaaaaataa actatatgac
     3481 aaacgtttga catattttta agatatgcta aaataaattt gcatttcagt gaaccgtttt
     3541 cacgtaaaaa taaaaaagga gtgattcgaa tgaattacag taaagtagct tccgacgtaa
     3601 tacaagcggt cggaaaagat aaccttattg cagctgcaca ctgcgctaca cgtcttcgtc
     3661 tcgtactaaa agatgacacg aaagtgaatc aaaaagcttt agacgaaaat ccagatgtga
     3721 aaagcacatt taaaattgat ggacaatatc aagtgattat cggtgcaggt gatgttaatt
     3781 tcgtttatga cgaacttatc aaaaaaactg gactttcgga aatttcaaca gatgatttaa
     3841 aacaaattgc tagtaaagat aaaaaattca accccattat ggcattaatt aaattattat
     3901 cagatatttt tgttccaatt atacctgccc ttgttgcagg tggtttatta atggcattac
     3961 aaaacttttt aacagctgct ggactttttg gaccaaaatc aattgaagaa atgtatcctg
     4021 cgattgaagg tatttcctca atgatccaac tgatgtccgc tgcaccattc atgttcttac
     4081 caattttagt aggtatttca gctgctaaac gttttggagc aaaccaattt cttggtgctg
     4141 caattggtat gatcatgaca acaccagatc ttggtggctc aactgaatat tggaatattt
     4201 ttggttatca tgtttcacaa acaaactatg cttatcaagt tattccagtt ttagcagctg
     4261 tttggatatt atctatatta gaaaaattct ttcataaaaa attgccatca tctattgact
     4321 ttacattcac gccattatta tcagtaatga ttactggatt tttgactttc acagttattg
     4381 gccctgtaat gttattgttg tctaatggaa ttacagacat tattgtttgg ctatataaca
     4441 ctactggatt tattggaatg ggtatttttg gaggaacata ttcacttata gtcatgactg
     4501 gtttacatca atcatttcca gctattgaaa ctcaattact ttcagcgtgg acaaatggta
     4561 tcggacatgg agactttatc tttgtagttg catctatggc aaacgttgct caaggtgctg
     4621 caacatttgc catttggttc ttaactaaaa attctaagac aaaaagtctt gcttcctctg
     4681 cgggtgtctc agcacttctt ggaattacag agcctgcctt gttcggagtt aacttaaaat
     4741 accgctttcc attcttttgt gctttaattg gttcaggaat tgctacagca gtagcaggat
     4801 tacttaaagt agttgctgtt tcacttggtt cagcaggttt cttgggattt ctttcaatta
     4861 atgcaacatc tattccattt tacgtattgt gtgaattgat tagctttgta gttgcttttg
     4921 caattactta cttctacggt aaaacaaaag ctgctggtat ctttaaagca gaagaaattg
     4981 ctgaacaaac accagttaat tcttcaaaag tagcaacaac agatccaata tctactgatg
     5041 ttgaatcaac acaaacaaaa gtttcatcag aaacaattgt tagtcccatt tctggtaaag
     5101 tgattagtct ttcttcagta aatgatccag tcttttcatc agaagctatg ggaaaaggga
     5161 ttgccattaa accaaatgga aacacggtcc attctccagt agatggtact attcaactca
     5221 cgtttgaaac tggacatgct tatggtatta aatcaaataa tggtgctgaa gttctaattc
     5281 atattggtat tgatactgta tcaatgggag gaaaaggatt tacacaaaaa gttactacta
     5341 atcaaaaagt tagaaaaggc gatattcttg gagcatttga ccgttcaatg attgagaaag
     5401 aaggtcttga tgatacaaca atgattattg tgaccaatac ttcggattat tcagaagtaa
     5461 atatagtagc tgaaaataca gtcactgagg gtactgattt acttgaaatc aaataaatat
     5521 atttccctga gtaaagatgg aattttcttt ccaaaatcaa ataatataga ttaatcaaat
     5581 atttgagaat aacattttat ttaatctttt catatatcaa ttgtatgaaa aattattaga
     5641 attttaaaaa atgataaaaa ttcaaaaaga aaaaatagta gttatttact tgtcatgtta
     5701 ctaaataaaa aaataattta aatatgatat atagtcattt atttagtgat ttcattctaa
     5761 aataaaggga gaaatgtcta tgctatacgg tgcaattgaa gcaggcggca caaaatttgt
     5821 gtgtgccatt ggcgatgaag aaatgacgat caaggaaaga gtgagctttc cgacaacgac
     5881 acctgaggaa acaatgcctt tagtcattga cttcttcaaa caataccaag cagatttagc
     5941 agggattggg attggctcat ttgggcctat cgatatccat cgcgattccg ccacttatgg
     6001 gtacattacc tcgaccccga aattggcatg gcaaaatttt gatttcatcg gtaccatgaa
     6061 aaaagaattt ccgatcccga tttcttggac aacagatgtc aatgcggctg cctatggtga
     6121 gtatgtcttc ggcagtggca aaggattgag cagtgtcgtt tactatacga tcggtacggg
     6181 tgttggcggc ggtgccttac aagaagggcg ctttatcgaa gggtttagtc atccagaaat
     6241 ggggcatatg ctcgtcgtcc ctcatccaaa agatgacttt gctggcagct gtccatttca
     6301 tggcaactgt ttagaaggga tggccgctgg acccgccatc gaaaaccgct tagggaaaaa
     6361 aggacaagag gttgcagaag atgatcctta ttgggaaatc gaagcctcct atattgctca
     6421 atgtgcctac aatacaacct tgatgttttc tccagatgtg atcatttttg gcggtggtgt
     6481 gatgaaacaa cgccatatgc tgcaaaacgt ccacgacgca tttgcaaaat tggtcaatgg
     6541 gtatgtcgaa acacctgagt taagcaaata tatcgtgacc ccagcattag aagacaacgc
     6601 tggaacgctc ggttgtttgg cattggctcg agaagcggtc ttacattcat aaacgaaaaa
     6661 aggctcttcg acatttagtg ttggtagaga aagatacaac tgaaaattta gtcataacca
     6721 gttaggcaga gtgcttaact ggtttttgtt ttacttggaa gatcaagcct tgaatgagat
     6781 aaattcttgc tcgaaagtta tggaaatttc gatagccgta ggccacttgt attgtgcaat
     6841 agttttttac aaaaaaaagg gggtgcggat atttttttgg acctttttaa caaataggtt
     6901 ctgttgcaaa gttttaaatc tactatcaga taaggtagaa taatagaaaa agatagcagg
     6961 aggaatgacg atgagtcatt ttaaaggaaa gcaatttca
//
LOCUS       DBBGSZ010000075         6869 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.080, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000075 DBBGSZ010000000
VERSION     DBBGSZ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6869
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.080"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..227
                     /locus_tag="ACIZE5_002657"
     CDS             <1..227
                     /locus_tag="ACIZE5_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6109754.1"
                     /translation="KTTEFDILHALMSTPNKVFSRSDLIEKVKGIEFDGLDRSIDSHI
                     KNLRHKIENDAKSPMYILTVHGTGYRFGGH"
     gene            227..1620
                     /locus_tag="ACIZE5_002658"
                     /pseudo
     CDS             227..1620
                     /locus_tag="ACIZE5_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294791.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
     gene            1635..1841
                     /locus_tag="ACIZE5_002659"
     CDS             1635..1841
                     /locus_tag="ACIZE5_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109755.1"
                     /translation="MFQKQIKIAKLVCECWAKKIFFQLISIDSVEKVHLDILSNSVVI
                     FSKKDLSIATIKKEVFGLQIYEMT"
     gene            1862..2458
                     /locus_tag="ACIZE5_002660"
     CDS             1862..2458
                     /locus_tag="ACIZE5_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdhK family protein"
                     /protein_id="HGC6109756.1"
                     /translation="MKTVKKMTKLVFASLGIIVFLGACSNQSESNNSNSTNEESTSTA
                     SSEMNSMEGMNHEGMVPSSMKDAANPKFPVGSNVILLGDHMEGMKGANAQVVGAFDTT
                     MYEVSYEPKTGGPMVNNHRWVVQEELKDTETVANEGDTVILNADHMDGMMGAEAKVDK
                     SITGTVYVVNYTPTDGQEEVKNHMWVTEDEMEYDENNE"
     gene            3410..4009
                     /locus_tag="ACIZE5_002661"
     CDS             3410..4009
                     /locus_tag="ACIZE5_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6109757.1"
                     /translation="MKSVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLRDVLEISRGRVIVKERLAMKEQKTAKHNSVFISNKLRKVILDYVQSEFPEQ
                     LQAQDFSKYLFPSRKGADTPLTRQSLWRIIHEAGTAVGLKEIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            4058..4774
                     /locus_tag="ACIZE5_002662"
     CDS             4058..4774
                     /locus_tag="ACIZE5_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HGC6109758.1"
                     /translation="MNEEKQPNFPDKYHLSRKESVYLLKKNIVELVYNAGKFEGLNTT
                     LLQTEGIIKYNRANNVAVDDVLTVVNLKRGFEMLLNDVQEPLLETSKRINRIVAAEDA
                     LFPGEIRTGGVELSTIQGRYVPPMLTEDEVNNQYGEIMNQEISDTEKALRLFLFISKN
                     QIFWNGNVGTALLIANKIMFSNGLGLLSIPENVFMKFNELLSKYCNSNLLVNESNIIS
                     FLYEQCIFGINYLKIIQHTI"
     gene            4788..5567
                     /locus_tag="ACIZE5_002663"
     CDS             4788..5567
                     /locus_tag="ACIZE5_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002396205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HGC6109759.1"
                     /translation="MMTIDEAKQLATYFSVGSAGYILDFTNVTWNIFTKKIVGIEIQN
                     HYGGSKGVSFQKFLLDDQFDDSLKNRLIQSLKGIMDRDKKYESTEMNPIVQLLFEEVF
                     KEDTSTALRKMKFSSEIDLLYIRQLPIRIQTDIKNKDFDSVLTKANTLIDEVLKFIIE
                     NTEGPSVNINLFKSKELRKEVFGRLNIKTEKDMDNRIKALVGALNTLSDKILEMRNSQ
                     GDAHAHGSNRIVIKEEEAILVANSSMVLCEYVFTKYKGLNR"
     gene            5650..6006
                     /locus_tag="ACIZE5_002664"
     CDS             5650..6006
                     /locus_tag="ACIZE5_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGC6109760.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVDNGRYVITHGFTKKTEKTPITE
                     LKHAKELREEWFTNDD"
     gene            5996..6262
                     /locus_tag="ACIZE5_002665"
     CDS             5996..6262
                     /locus_tag="ACIZE5_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6109761.1"
                     /translation="MMIKKLIEEKKKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            6421..6699
                     /locus_tag="ACIZE5_002666"
     CDS             6421..6699
                     /locus_tag="ACIZE5_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109762.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYVNNSSGQSVINKQIVENRVLLQSFKNKISFCIISSF"
     gene            complement(6696..>6869)
                     /locus_tag="ACIZE5_002667"
     CDS             complement(6696..>6869)
                     /locus_tag="ACIZE5_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HGC6109763.1"
                     /translation="HRSIKRRHKLYQSLRTASTTIKGMETIRGIYKKSRKEGTLFGFS
                     VCTEIRILLGIPA"
BASE COUNT         2527 a          957 c         1333 g         2052 t
ORIGIN      
        1 ttaaaacaac tgaatttgat attctacacg ctctaatgtc cacacctaat aaagtctttt
       61 ctcgtagtga tttgatagag aaagttaagg gaatagaatt tgatggacta gataggagca
      121 tcgattctca tataaaaaac ttaagacata aaattgagaa tgatgctaaa tcacctatgt
      181 atattttgac agtccatggt acaggataca gatttggtgg ccactaatga gaaaaagaac
      241 gataaaaact caattagctg tttccttttt agcaatcgca acattaataa taggatcgat
      301 tagtttagtc gcattaagtt tgatgaacaa tcattttagt aaatacgtgg aagagcggca
      361 agaagatttg ttgaatcagt atgtatatac aattgattta ttgtggttaa atagtgggga
      421 aacatggaat agtgaagaac ttgcagcact atctgagaaa gtattagaga ataatattta
      481 tttttctata gaagacgaac aaggcaacat ggtttgggaa cttactggaa aagatttgaa
      541 gtcagcacag gagaaactga aaaaaatgca ttgaaagttt ctgagaaaaa cagtgtgaaa
      601 ctagacgaaa caatagaagt gaaaaagaag ttaattaatg atggaaacga gtttggaaaa
      661 gtaacgtttt attatttcgg accttttgct tatacagagc acgatgcctt gtttatctcc
      721 agtatgaaac aaagtttaat gtatgttgca attgcagctc ttcttgtatc attcatactt
      781 gcttcgtgga tctctgctag attaggattg ccactaaagc atgtaagcga ttttacacat
      841 aaattaactc gtggggaata tgctgataaa atcccacaag aaacttcaat tattgaaata
      901 aattccttaa ttgattccct aaatgattta agtaatcagt tggagaaaca gcatgggctt
      961 cgaaaaagat taactaccga tatttcacat gaattaagaa ctccattagc tacgcttaaa
     1021 ggcaatgtgg aaggaatgat tgacggagtc tggaaaataa ctcccgagcg cctacaatct
     1081 tgttatgacg aaatagatcg tctaactcgt ttaattggaa atatagaaat aatcaacaaa
     1141 attgaagcaa aatatgatca tttaaataaa actgagttta acatatataa gttgattgaa
     1201 tccgttattg aaaatttcgc cagcaaaatt gagtcaaaaa accttcatgt tgaaatccaa
     1261 ggggataaca tcaatatatc tgcagataaa gataaaatga accaagttgt tatcaatctt
     1321 ttgaataatg ctattaaatt tacgcaaaag gagggaacca ttaagttttc tataagtaaa
     1381 aataaagacc atgttctttt aattgttgaa gacaacggca tcggtataga aaaagatcag
     1441 caacttcata tttttgatag attttatatg gctgacccct ccagaagtag agctttaggg
     1501 gggcaaggta tcggattagc tattgtaaag agcgttattg aagcgcataa aggtagtata
     1561 actgtaaaaa gtaaattagg tctaggaact aaatttgtta taaagttacc atttcaataa
     1621 aggaggagag ttatttgttt caaaaacaga taaaaattgc taaactagta tgtgaatgtt
     1681 gggcaaaaaa aatatttttt caactgattt cgatagatag tgtcgaaaaa gttcatttag
     1741 atatcttatc aaattctgta gtaatctttt ctaagaagga cttatcaata gctacaatta
     1801 aaaaagaagt ttttggatta caaatttatg agatgaccta aatgtgatta attaaaggag
     1861 gatgaagaca gtgaaaaaga tgacaaaatt agtatttgca agtcttggaa ttattgtatt
     1921 tttaggagcg tgtagcaatc aaagtgaatc gaataattct aatagcacaa acgaggaatc
     1981 gacttctaca gcgtctagtg aaatgaatag tatggaggga atgaatcacg aaggtatggt
     2041 tccttcttca atgaaagatg ctgcgaaccc taaattcccg gtgggaagta atgttatact
     2101 gctaggcgat catatggaag ggatgaaagg tgcaaatgct caagttgtag gggcctttga
     2161 tactacaatg tatgaagtaa gctatgagcc aaaaactggg ggaccaatgg ttaacaatca
     2221 tcgatgggta gtacaagaag agttaaaaga tactgagact gtagcaaatg agggcgatac
     2281 tgttatcttg aatgccgatc acatggatgg gatgatggga gctgaagcaa aagtagataa
     2341 atctattaca ggaactgttt acgttgttaa ttacactcca accgatggtc aagaagaagt
     2401 taagaatcat atgtgggtaa ctgaagatga gatggaatat gacgaaaata atgagtaatt
     2461 ttatatacta aaccaacaag ctggtacatg gtcttcgtat tctcaacatg aggaatatga
     2521 gctctttgtt aataaggact gatgagttgt gcaaaatcaa atctgggtca gaacgaacct
     2581 cattctggct cagatttttg gctcttcgac atttagtgct ggtagagaga caactgaaaa
     2641 tttagtcata accagttagg cagagtgctt aactggtttt tgttcgcatt tattattctt
     2701 ttgatattgg ctgcttgccc ttcaatttta tttggtttct taatcaactc ttcatataac
     2761 cccaaatcat atattaatga ggtgcctcct attcctataa atctatctct tctttaatag
     2821 tatgagaaaa gtctactctt gtagatttaa attgtcaaca aaaaatttac agatgtaaat
     2881 gataagttga atagagaaag ataaattatt tttttggtat tcatataagg ttaattatgt
     2941 attatcacaa aatgattgtt gtcgaataac taaaagtgtc aaaacaatga tgaaatcatt
     3001 tagttcttat aaattagaca agagaaaata aatattccat atctacttta ttggatccat
     3061 aacatgacta aattctgaat actttttaaa gcttatcatt tggtaaaact gaatataagt
     3121 taattatata gactgaaaat tttgaatttt cagaatagaa taacttaaaa gtactgacaa
     3181 attttttaaa ggggcaatat taatgttctg agataatcaa atcttaccga aaatatcaaa
     3241 agtccaatgt gacacaattg gattttgtca cattcgttaa aatcgctcca tccttagagg
     3301 ctctaatagg aaatcacttt tcttttagcg ccttttttct atagcttgtt taaatgtgac
     3361 ttattatctg ttataatcgt attaagtaac atttgagagg tgtctaaaaa tgaaaagcgt
     3421 ggaaccgatt cgcgacaaaa aaaagatcga tgccatgaag gccattttgg cttccggaaa
     3481 atatgggcaa cgaaatttgg tgcttttttc gatcgggatc aatacagcct atcgaatctc
     3541 cgatttaaga cagttaaaat taagggatgt gctagaaatt tcccgtgggc gggtgatcgt
     3601 caaagaacgt ctggccatga aggaacaaaa aacggccaaa cacaattcgg tcttcatttc
     3661 gaacaaattg cgaaaagtga ttcttgatta tgttcaatcc gaatttcctg agcagttgca
     3721 agcacaagac ttcagcaagt atttgtttcc aagtcgaaaa ggagcagata cgcctttgac
     3781 ccgacaaagc ctttggcgga tcattcatga agcaggaact gcagttgggt taaaagaaat
     3841 tggtccccat tcgatgcgta agacctttgg ctatttttta tacaagcaag gaaccaaaac
     3901 agagatcatt cagtcgctgc taaaccattc ttcacaacgg gagaccttac gctatattgg
     3961 aatcacccag gaagacaaag atactgcagt aaagagtttg gatttatgac agaataatgc
     4021 cctatataat agaaggaaaa attcaagagg tgagaaaatg aacgaagaaa agcagcctaa
     4081 ctttcctgat aaatatcact tatctcgcaa agagtctgtg tatttattga agaaaaacat
     4141 tgtagaactg gtgtataatg cggggaaatt tgaagggtta aatacaacgt tgttacaaac
     4201 agaagggatt attaagtata atcgggccaa caacgtggct gtagatgatg tcctgaccgt
     4261 cgttaactta aaaagaggct ttgaaatgct tttaaatgac gtacaggagc ccctgttaga
     4321 gacaagtaag cggattaatc ggatcgttgc agcagaggat gcgctttttc ccggtgaaat
     4381 acgaaccggt ggggtagaat tatcgacgat tcaaggaaga tatgtgccac caatgttaac
     4441 tgaagacgag gtaaacaatc aatatggtga gataatgaat caagagatat cagatacgga
     4501 aaaagccctg cgactgtttc tattcatttc gaaaaatcaa atattctgga atggtaatgt
     4561 gggtacagcc ttgttgattg cgaataagat tatgtttagc aacggtttag gactattatc
     4621 aatacccgaa aatgtattta tgaaatttaa cgaactttta tcaaagtatt gcaacagtaa
     4681 tctattagtc aatgagtcaa atattatatc atttttatat gaacagtgta tctttggtat
     4741 taattatttg aaaataatcc aacatacaat ttaagaggta taagtaaatg atgactatag
     4801 acgaagcaaa acaattagca acttattttt cagttggttc agcgggatat attttagact
     4861 ttactaatgt aacgtggaac atatttacaa agaaaatcgt agggattgaa atacaaaatc
     4921 attatggggg ctcaaaggga gtatcctttc aaaagtttct gcttgacgat caatttgatg
     4981 attcgttaaa gaatcggtta atccaatctt taaaaggtat tatggatcga gataaaaaat
     5041 atgaatctac tgaaatgaat cccatagttc agttgctttt tgaggaagta tttaaagaag
     5101 atacttcaac tgcattaaga aaaatgaaat tttcaagcga gattgattta ctttatattc
     5161 ggcagctacc cattaggatt caaacagata ttaaaaacaa ggattttgac tctgttttga
     5221 caaaagcaaa tactttaata gatgaagttc taaaatttat tattgaaaat accgaaggac
     5281 cgagtgttaa tattaattta tttaagtcaa aagaattaag aaaagaagta tttggccgcc
     5341 tcaatattaa aactgaaaaa gatatggata atagaatcaa agcccttgtt ggagcactca
     5401 atacattatc agataaaata ctcgaaatga gaaatagtca aggagatgct catgcacatg
     5461 gctcaaatag aatagtaatt aaggaagaag aagcaattct tgttgcaaat tcttctatgg
     5521 ttttgtgcga gtatgtgttt actaagtata aaggattaaa tagataataa aatgcatatt
     5581 ttatagtata caattcgaat ttttatgtta tatactataa tataaaatca atatatgata
     5641 taattgggta tggaaaaaat atcttttgaa acatttaaaa gacccaatgg tcatgatgaa
     5701 tttttagaat ggttggaaac attaccaaaa aaagatagtg cgaagctttt acgtacaata
     5761 gaagaaacag aaaagaatgg gatgctagta gctcaacggt tgaaatgggt gaaaaaatta
     5821 gacactaatt tgtacgaatt aagaagtaag gtaggatcaa acatccaaag agccatctat
     5881 ttccatgtgg acaatggaag gtatgtcatt actcacggat ttactaaaaa aacggagaaa
     5941 acaccaataa ctgaactcaa gcatgcaaaa gaacttagag aggagtggtt cacaaatgat
     6001 gattaaaaaa ttgattgaag aaaagaaaaa agataaagat tttgcagaag catatgaccg
     6061 tgaaggaaga aaactcgaaa ctgcggttgc tctttatcat gctcgggagg aagcagggct
     6121 aactcaagcg gagcttgcac aaaaagcaca tacaactcaa tctactattg ctcgaattga
     6181 gagaggggat aacgtatctt tcgataaact tgatgatatc gccagggcat taggtaaaaa
     6241 gctggtagta gaatttgctt aaaagcgagt tgaaaatata tctataatag gctcctaact
     6301 aatcaattag tttagtgggc ctttttttac tagatagata aaggttgtac tatagtgtaa
     6361 aagacaataa attttatact aaaattactt taaagagaac tagagagaaa ggtacaataa
     6421 atgaaaacca taaatcttat aaaagtattt atagcatcac caggtgatat agcagcaaaa
     6481 aggaatgaag tagaagaaac catatataga tggaatatag aaaatacaga taatacaaaa
     6541 gtgattttga tgcctatacg atgggaaact aatgcgattc ctacttatgt aaataatagc
     6601 tctgggcaaa gtgttattaa taaacaaatt gtagaaaata gggttctgct gcaaagtttt
     6661 aaaaataaaa tcagtttttg tattatttct tcattttaag ctggaattcc caataatatc
     6721 ctgatttcag tgcagactga aaagccgaag agagtgcctt cttttcggct tttcttgtag
     6781 attcctcgaa tggtttccat ccctttaatt gtggtggaag ctgtacgtag actttgatac
     6841 aatttatgtc gacgttttat cgatcgatg
//
LOCUS       DBBGSZ010000076         6674 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.081, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000076 DBBGSZ010000000
VERSION     DBBGSZ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6674
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.081"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(51..1517)
                     /locus_tag="ACIZE5_002668"
     CDS             complement(51..1517)
                     /locus_tag="ACIZE5_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HGC6109764.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1904..2500
                     /locus_tag="ACIZE5_002669"
     CDS             1904..2500
                     /locus_tag="ACIZE5_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGC6109765.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
     gene            complement(2558..3040)
                     /locus_tag="ACIZE5_002670"
     CDS             complement(2558..3040)
                     /locus_tag="ACIZE5_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109766.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3146..3343)
                     /locus_tag="ACIZE5_002671"
     CDS             complement(3146..3343)
                     /locus_tag="ACIZE5_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109767.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3638..4396
                     /locus_tag="ACIZE5_002672"
     CDS             3638..4396
                     /locus_tag="ACIZE5_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HGC6109768.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4456..4884
                     /locus_tag="ACIZE5_002673"
     CDS             4456..4884
                     /locus_tag="ACIZE5_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109769.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4930..5002
                     /locus_tag="ACIZE5_002674"
     tRNA            4930..5002
                     /locus_tag="ACIZE5_002674"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4963..4965,aa:Gln,seq:ctg)
     gene            complement(5152..5523)
                     /locus_tag="ACIZE5_002675"
     CDS             complement(5152..5523)
                     /locus_tag="ACIZE5_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HGC6109770.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5738..5923
                     /locus_tag="ACIZE5_002676"
     CDS             5738..5923
                     /locus_tag="ACIZE5_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109771.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6006..6194)
                     /locus_tag="ACIZE5_002677"
     CDS             complement(6006..6194)
                     /locus_tag="ACIZE5_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109772.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6218..6481)
                     /locus_tag="ACIZE5_002678"
     CDS             complement(6218..6481)
                     /locus_tag="ACIZE5_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109773.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
BASE COUNT         2216 a         1303 c         1079 g         2076 t
ORIGIN      
        1 aaaaacagga actgctgcaa ataagcaatt cctgttttta tgttcattga ttaatgaata
       61 gagcccatta gttttttgat tggttctttc acagtaaata gcaagatacc accgacgatt
      121 gctactgcac cgataatacc gaagtaagca gattctgttc ccggtgtgta gaagcgtgca
      181 atttgtgcat tgattgcttg tgaagaagca tcagctaaga accaaatagc gattgtttgt
      241 gattcaaatg ctcgtggtgc taattttgtt gtcacagaca aaccaactgg tgaaagacac
      301 aattcagcaa taaccacgat gaagaaactt cccaacaacc acaatggact tacttttcca
      361 cttgtaccat aaagcatacc cggcaacatc aatagcaagt acgataatcc tgcaaataaa
      421 agtccaagag agaatttcac tactgtagat ggttgacgtt caccaagttt cgtccacatc
      481 gttacgaata ctggtgtcag aataaagatg aaaattggat tcaatgattg ataccagctt
      541 gcttggatcg ttacaccaaa tagcgtagat tgtgtacgtt cactagcaaa taaagctaag
      601 atagatgaac cttgttcttg taatgaccag aaaatgattg ctgcaaggaa taatgggata
      661 taagcccata ctcttggttt ttcttcagca gttacatctt ttgaagtcag cattttgata
      721 aagtaataca acggtaagat aatccccaat acactgattg tattgacaaa aaagtcaatt
      781 gtcagatgac cagttagttg tgccccgccg aatactgcag cgataacaac aagtgcgatg
      841 atcaagttac ggatgaatcc tttacgttct tcagttgtca aaggattcgg cggtgttgta
      901 cccactccgt ctaatgtctt gcgtccttgg atgatgtatt gtaataatcc aaagaacatc
      961 ccaatagcag ctaaagagaa ccctaaatga tagttatatt cttgaccgat tgtaccaacg
     1021 attagtggtg ctaataatgc ccctaagttg acacccatgt aaaaaatcga aaatcctgca
     1081 tctcttcgca agtcagtctt tgaataaaga tgtccgacca tgccagaaac atttggtttc
     1141 aaaaaggcgg ttccgataat aatcaatgcc atcgaaacaa acaatgtact tacaccaaat
     1201 ggtaaagcca agacgatgtg gccaagcata atgaaaactc caccgaagaa tacagtgcgt
     1261 tttgctccta acactcggtc agatacccat ccgccgacga tactagacat gtagatcaaa
     1321 gatccgtaga tcgacatgat agctaatgct gttgctcgtg gtaatccaag tcccccgttg
     1381 gcaactgtat cgtacatata atagataagt aatgcacgca taccgtaata actaaatcgt
     1441 tcccacatct cagtgaagaa caaagttgac aatcccttcg gctgcccgaa gaagcccttg
     1501 tcttgctgtt tttccataat ctatacccca attctttaaa ttttcagaaa atattataca
     1561 tctttaccga aaaatttaac taaaaaactt atttaagaaa tataaactaa ttttctataa
     1621 aagcaagtaa tttttaatgg caatatcata aaaaaaagaa gatagagatt taataattat
     1681 atatcagctg tttttttcaa ataagcaaaa attcctaaaa cacaacaatg aaagcgataa
     1741 ctaagaaaat ccttacataa cgatttttct tattaaaatt gttttttgaa cttcgcttat
     1801 tttttgtgag catatctgtt tacttacttt ttgtaaggtg ctatacttca tttcgtaatc
     1861 aattaaaaaa atgcaaaacg caaatcaaag gagaaatttt attatgacaa cttttactga
     1921 cactttgaaa aaccgccgtt caatctatca tctaggacgt aatgtttcac tttctaatga
     1981 agaattaaca actttgatca aagaagcaat taaagaaagc ccaactgctt tcaatgctca
     2041 atcaacacgc gcagttatcc ttttcggaga tgcacatgaa aaactttggg aaatcactga
     2101 agaagcactt cgcccattga ctccagcaga agctttccca aatacacaaa acaaattagc
     2161 tggtttcaaa aatggttatg gtacagtatt attcttcaaa gatactgacg tggtaaaagg
     2221 tctacaagaa caatttgaat tatatgcaga caacttccca gattggtcag aacaatcaaa
     2281 cggaatcgca acagctaata cttgggtagc attagttgat aaaggattgg gcgcaaactt
     2341 gcaacattac aacccagtta ttgacgaagc agttgcaaaa gaatggaata tcccttcaaa
     2401 ctggaaacta cgttcgcaat tagtattcgg ttcaccagaa acaccggctg aggaaaaaga
     2461 atacatgaac gatgccgatc gcttccgcgt atttggataa ttttatttga aataaaaaac
     2521 agaggttgtg acaaacatct tgtcgcaacc tctgttttta ttctggatca atcataatat
     2581 caatctctgc ctcatcgttt aagcgttggg acaaaaatgg aactaattct tctaatgatg
     2641 cagaaaattt cagcatcggt cctcgccatc cgtttcggaa aaaattcatt tttacgattt
     2701 tagaaccttt tggctgatat aatacaattt tattgatctc agaaaaagga acaccttttt
     2761 tgtcaaagct attcaaaaca agtccttctt ctgtgattcc tctactgtcc aacaaaaaac
     2821 taataaaaat cattgctgac aagatccctt ttgccaattc atctgctgta ggatgactga
     2881 tgagtgtata ccaaatgact agtgacacta agaagggtat caccaagtag acccatcgat
     2941 ttcgcacagt ccgataaata atttcttttc gaaccagcca aagaaataaa aacatcacaa
     3001 caacgaataa aaacaataga accgtaaaga atgttaccat gacaactcgc ctcgcttttt
     3061 cttctccaga aaataggaaa agaatactga tttaccttct caaagaaatt ggacttgcag
     3121 cacgccgcac gtccaattgt tttctttatt caaatgtatc atattttgca acaaccatgc
     3181 ttgctttttc atctaataat tcttggtcct ctgcagcaca ttgggcaact ttgaccacgg
     3241 cgcagtttgt catttttgat acaacttcac caatgaccgt ttttgtaaaa ccaattggtt
     3301 tgcatgcata ttgttctcct aaattaatca tttcttccgt catcaaaatc ctcctaaact
     3361 gctggaactt ttctccacat taccactgct atttctttgg agatttaact cattgatttt
     3421 tatttacagt taaaaatcaa ccttacaggc attatagcgt actgttttcg ttttcacaat
     3481 taaaacagct gttgtattta gaagaatttt tttcaaaaaa ttaaaacata ttccttaaaa
     3541 actaattatt tcctacatat taaaatataa tacttccatt tccaataaaa atacatttat
     3601 aataggaaag ataaacagct gaaaagggag atttcaaatg aagaaaaaaa cgttcaaaaa
     3661 actattgttt ctagggggca cagctgctct tttattaagc ggtacaagtt attacctaca
     3721 tatccattct ccagaacata caatgaacac tgcacaaaaa agttcaacac aaaaaacgaa
     3781 aaagacaaaa gagaaagcag aagttttact agatgttcca ttagagagcc agtttgattc
     3841 tccttcttta gaaaatggct gtgaagtcac ttcgctttct atgcttttat ctttttatgg
     3901 ttatgaaaca actaaaaacc agttagctga gcaattggat tacgtccctg ttttcaatgc
     3961 agatgggact catggcgatc ctaatgaagg atttgttggt gatatcagtg gcggagactg
     4021 ggctatggtc gtctatgttc ccccagttgc ctcccttgct cagcaaatcg tccaaacgga
     4081 ttatcacact tttccaaaaa ccgatgctca actcgatgat atcaaaaaag cactatctaa
     4141 aggaaatcct gtctggactt ctgtgactat caattttgaa gtcccagatg aaactgattt
     4201 tatgacttgg accacaaata atggagaagt aagagtcact cctcttgttc atgcttgtgt
     4261 agtcactgga tatgacaaag aaaatattta tgtcaacgat ccctatggtg taaaaaatcg
     4321 agcagtaccg atcaacgatt tttcggcgat tttcactgca atgggtggac agatgctaac
     4381 tttggagaaa agctagtaat tcaaacaaaa atcccttata ctcaagatac caaacctttg
     4441 aagggagcgt agataatgga aaaattcaca cataaaaaaa tggatccaaa tgaaattccg
     4501 attatttttg tccgtgactg caagggaaat gttcaaggta aagtctctat taatgagtgg
     4561 aacgagcgtc gcagacctgc taccctcaat gaactggaaa tcaaattgta tcgtcaatct
     4621 cttgtttatt acgcagatca agagtacgag aaagccaccg atttattgaa atttctaatt
     4681 gctcgaacag agtatactcg ctttgaatat attgaacgtt tagcaaacat ctatcatatt
     4741 atgaatgaac ctgtcaaaga atatcagtta ttggacaccg tcttgtcagt agcagaactg
     4801 attgcccttc ctgctggatt agaaaagaaa ctagtacgcc gccttttacg agtaaagcaa
     4861 caactatccg atcaagaaaa ataacttgcg tttttttagg aaagtgctat gattattttg
     4921 ttgaataaat gggatgtagc caaactggta aggcacttga ctctgaatca agcaattgta
     4981 ggttcgaacc ctgccatccc aatttgatgt gcttgctgaa aaaatgaacc ccctgtaaaa
     5041 gaacaatctt tttgcagggg gattattgta ttatttttac tacttgtatt tagtttacat
     5101 aattaaatta tgaataataa aatcgggcgt attcttaata caaaaactga tttacccaat
     5161 aattgctaat gctttctccg gaactttttc tctaggaact tcctcatacg tttctatgtg
     5221 tgctccttta ttgctaattt tcaaataatg attttctttt aacacagaaa gaccattaaa
     5281 ttcaaccgtt cgttctttcc cattggcatc agcagctttc tgcacatacc ttgctgtacc
     5341 atattcattt acttcctctg gtttttgtgt ctttacatag acctctcctt tttcaactaa
     5401 tggatttagc tgatcaagta taccagggat ttctccataa cttccttcag tataatattt
     5461 cagtccaaat agcaaaatac cactaatcgc cgccagtcca atcaaatatt taatcacttt
     5521 catctttcta cctccttgtt atatattcag tatatgggtc agttaaagaa attccatccg
     5581 tcccaagttg gagatttttc tcctacttta gaagcgagaa tcgagtgttt ttttagtaaa
     5641 aatgatcgtt atttgatatt attgacgtgt ggataaatca gtttttctcg ttttgtccat
     5701 gtaaaaaatc atgttgatag caaaggatgt gttcaaaatg aatcaagaag aattatttca
     5761 aaaagtcaag gaaatgatta agaacggcaa tttcgatggc gcaaaacgat ttatcgaaga
     5821 acataaagaa caattaggac cttataaaga gaaagcccaa aatcttttaa aagatgtaaa
     5881 tatcgacagt gtcaaaaaca aatttaaaaa tctattcaaa taagtaaaac tttcactttt
     5941 gtaaaatcaa aggaggacaa tgctgctgca tcgtcctcct ttggttcttt tctgaatact
     6001 tcatactaaa ataaacgtgt cggatcgtaa tgataagtca cattgccgtt cagtgaggct
     6061 tttcccacca catatttacg attctccaac ttcagccacg cttctcgaaa agccattaat
     6121 tcttctcttt ttacatcaat cttttcgatt tttccatcga tcaaatcttg aataagttgt
     6181 tcatatggat tcattttttt cctccatctg ctgtcaatca ataagttgta aaaataggtt
     6241 catatgcttt tttggtatct agatcttctc tgactttgac tgtcgtataa ataatttttt
     6301 ctactgggat actataataa cttccttcac cattattgaa tcggtgaacg tctttctttg
     6361 ctaaaatacc atttatttta ttcgtcagta cacgttgttc gacactgtta cttacaacat
     6421 agtaaatcac ccgaatatta ttgatcaaat gcaaatcgat ttctaacact acatgatcca
     6481 tgaaaatccc actccttctt tcactttgat tatagcaagt ttctcctcta atttcaaaat
     6541 cgatacagat tttaccggat aaatccacaa aactgcttgc gccatttcgc acaaagtgtt
     6601 attttgtatc atggacttta tttatcggag gcaatagtat gatcgcgatc ggtcaatttg
     6661 ttttttatat tcct
//
LOCUS       DBBGSZ010000077         6391 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.083, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000077 DBBGSZ010000000
VERSION     DBBGSZ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6391
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.083"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            330..1175
                     /locus_tag="ACIZE5_002679"
     CDS             330..1175
                     /locus_tag="ACIZE5_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC6109774.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="ACIZE5_002680"
     CDS             1456..2676
                     /locus_tag="ACIZE5_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HGC6109775.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="ACIZE5_002681"
     CDS             2673..5393
                     /locus_tag="ACIZE5_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC6109776.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="ACIZE5_002682"
     CDS             5377..6321
                     /locus_tag="ACIZE5_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGC6109777.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2379 a          987 c         1231 g         1794 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttcttt t
//
LOCUS       DBBGSZ010000078         6210 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.084, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000078 DBBGSZ010000000
VERSION     DBBGSZ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6210
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.084"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..206
                     /locus_tag="ACIZE5_002683"
     CDS             <1..206
                     /locus_tag="ACIZE5_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HGC6109778.1"
                     /translation="KVEFVYQYTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVGY
                     RNQKLAQRILDNELGCANASEAV"
     gene            977..1711
                     /locus_tag="ACIZE5_002684"
     CDS             977..1711
                     /locus_tag="ACIZE5_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6109779.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1727..2896
                     /locus_tag="ACIZE5_002685"
     CDS             1727..2896
                     /locus_tag="ACIZE5_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGC6109780.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2912..3907
                     /gene="lacD"
                     /locus_tag="ACIZE5_002686"
     CDS             2912..3907
                     /gene="lacD"
                     /locus_tag="ACIZE5_002686"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HGC6109781.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3986..4912
                     /locus_tag="ACIZE5_002687"
     CDS             3986..4912
                     /locus_tag="ACIZE5_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HGC6109782.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4931..6181
                     /locus_tag="ACIZE5_002688"
     CDS             4931..6181
                     /locus_tag="ACIZE5_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGC6109783.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         2068 a         1025 c         1277 g         1840 t
ORIGIN      
        1 tgaaagtaga atttgtctat caatacacat ttgaaacctt acaacaattg gatttggagt
       61 tatttgacta tgtcaattgg tggaaccacc ttcggttgca cggtacactt ggctacgaga
      121 caccggttgg ttaccgtaac cagaaattgg cgcagcgaat ccttgataat gagctcggat
      181 gtgctaacgc tagcgaggca gtctaacttt aactgttagc tcctgccgaa gatcgtcaca
      241 tccgaggagg ctcattgtca aggacaatcg gaatagcata cggaaagaag ttctgcacct
      301 tataaaattt gtcaaaaaaa ctgttgccat tccaaagttt gaaaaatgct atttcgaggt
      361 agaaggatat tatataagca cggttgacta aacgaagtga taataaaaaa agttattcaa
      421 gaataagaaa aattatgata cgaattcaga taaactggag aatacagaga cctttaaaag
      481 ggataagaaa caacataaat tcctcttaag agagaacgaa aggacaaagc cagcaacttg
      541 atacacgagc tagtattaga ggaatttatt ctcatagact cccttttgaa tacgtttcaa
      601 ctttaatttt catgttcata aatgatttga aaccaaagca aatgcgttgc acttttcctc
      661 cgtcttccga aaatcgttca attcactggt aagtagtcat ttgatagttt gaggcaaatt
      721 gttgattgat gaagggtagg agctaaaaaa agataccagt tgaagagaga aaaagaaaaa
      781 aatagagggt gttcttgaat gaaaaaagtt ggaaaattat ttttcatttc cttttattcc
      841 tattaaagtc agtgatgtca atcatattaa caagactaaa aatgaaaata aaaaaaagat
      901 tgttcttagt attgactcat aaaaaatacc actactatac ttacattgtg gttatagcca
      961 gttaggagag acatcgatgc aaaatacctt tcaatcaaaa tcactttatt atcagctggt
     1021 agaaatattg aaacaacgaa tcgaaaacag tatggtcgct catgacaagc tgccatcaga
     1081 aagagagttg accagttttt atggcgttag tcgcacgacg gtgcgactag cattgcaaga
     1141 actggaaaaa atgggctaca tttatcgaca acatggaaaa ggaacctttg tttcggaatt
     1201 aaggacaaat gcgactgatc tagctggcgc atatagtttt accgaacaaa tgcgggcaat
     1261 gggcaaacat cctgaaacca agatattggc cttcaagaag attgaagcaa ctaaatattt
     1321 agcgagtcat ctgaatgttc aactaggtga gcctttattt caattagacc gattgcgctt
     1381 agctgatgat ttgccaatga tgatcgagaa atcctatttg ccagtgaagc tatttatgtc
     1441 cctttctcaa gaaattctat ttctgaaacc tttatataat ttgttttcag agaatttcaa
     1501 tcaaatcgta cggttggctg acgaggaatt ttatgccagc attgtccaga aagaagatag
     1561 tgagttgcta aatattccag aaggatcacc agtgctccat ttagttcgct caacctataa
     1621 tctcgagaac gaagtgattg aatttacatt aagtgtagcg cgggctgata aatttcatta
     1681 taagatcagg catctgcgtt ccactaactg aattggagga aagaaaatgt ttatgttctc
     1741 aaaagaagaa ctacgaaagc taggagcaga aaatactacc cgagaaattc gacagcaacc
     1801 ggaactgtgg catgagacgt ttgaccgtta tcaagaaaca gttgcagatt tagatcgttt
     1861 gtttacggat gcgaaacaac atgctggaga gcgaccaatc cgagtcattt ttacaggggc
     1921 cggaacctcg caatatgtgg gagatacact aattccgttt cttactagtc aaggaaatac
     1981 gaaccagttt atttttcaaa gtattggttc gaccgatatc gttgctacgc caaaagaata
     2041 cctgattcct gatgagacaa cgatcttggt ctcatttgcc cgtagtggaa atagtccaga
     2101 aagtctagcc gcagttaaga tggccaatca gctggtcaac aagatctatc atatcgtgat
     2161 cacctgtgca ccagacggat tattggctac acaaatgcct acaaaaaaag aaaatctagt
     2221 tttactaatg ccaaacaaag ccaatgacgc tggttttgct atgacaagca gtttcagctg
     2281 tatgacgctg actgcgctac ttatttttga tcaagcaagc aatcagcaaa aagaaagata
     2341 tgttcatcaa ttaagccgac taggagaaga agtcatccaa cgagaatcag agatccaagg
     2401 gtatctggca tcagactttc atcgcatcat ttacttaggt tcgggaagct taggcggatt
     2461 gactagagaa gcgcaattaa aagttctcga gttaactgct ggaaaaatcg caaccgtatt
     2521 tgatacatct ttaggattca gacatggtcc caaatctttt gtcaatgagc aaacattggt
     2581 tttcctgttt gtcagcaatg actcatatac gcagaaatac gatgtagaca tgctggaaga
     2641 aatcaaaaat gacggtattg cccaacgcgt tgttggaatt ggtcaaaagg gttcattgtt
     2701 tagtggtgat tcctttgaat tagttgcaga ttcgttactg ccggatggct atcttgcttt
     2761 agcagatatc atggtagccc aaacgatcgc attactttgt tcggtgaagg ttggtaatac
     2821 accagataca ccatcgccaa gtggaacagt caatcgtgtg gtcaaaggcg taacgattta
     2881 tccatatgaa aaataggaaa gagtgtgaag catgttagaa tggtcggaaa ataaaagaca
     2941 agcaatggaa cgtctatcga cgccagaagg cattattacc gctttggcga tcgatcagcg
     3001 aggcgcgctg aagaaaatga tgtcggcttt agggatggaa gcgacaaagg aaaaaattga
     3061 gcagtttaaa acactaattt cccaagaatt gactccttat gcctcagcaa ttttattgga
     3121 tcctgaatac ggactgcctg ctgcacagaa gcgtgcagca gcgagcggtc tgctgttggc
     3181 atatgaaaaa actggttatg atcaaaccgt acccggccgc ttgccggatc tgctgtcgga
     3241 ctgttcagtt ctgcgattga aagagttagg tgcggatgcg gtgaaatttt tactgtatta
     3301 cgattatgaa gaagcagagg aaatcaatcg gcaaaagcaa gtttttgttg aacgaattgg
     3361 aagcgaatgc atggctgaag gactgccatt ttatttagag ttattgtcat atgatgctaa
     3421 aaatgtagat acgaaatcgc tttcctatgc caaagcaaaa ccgcgcaaag tgatcgaaat
     3481 gatgaaagaa ttctcgaaaa cccagtataa agtagatgtc ttaaaggttg aagtaccagt
     3541 aaacatgtca tttgttgaag gaaatgcaac aggggagatc gcctatacac gtcaagaagc
     3601 tgccgcttat tttaaagaac aaagcgatgc aacagatttg ccgtatatct tcttaagtgc
     3661 tggggtatca gcggcattat tcatggagac attgcgtttt gccaaacatg ctggggcacg
     3721 attcaacggt gtactctgtg gcagagcaac ttggaaagat gcagtcgctc ctttcgttga
     3781 aaaaggagaa gcggcaactt tagaatggct gacagaacaa gggacacaaa acattcgtca
     3841 attgaatgaa gtgataagag aaactgccat cccatggtat gagaaagtaa gtgaaagcac
     3901 ttgttaatgt ttctaatata ttagtagtga taagagatat gtgtgattat aatttatcat
     3961 tattgaaact gggaggatat tttatatgaa taaaagattg ttagattatt cagcttcaga
     4021 ttttttgaaa gctaagccga tggaattaaa gcaggcaatt ttggcttctg aaggtagaac
     4081 aattatggca gaaaatgtgc caagtagctg tccttacatg ggaaaatcag tgacaaatgc
     4141 agaattggag agagctgctg gagctgattt aattttgttt aatgcactag atctttttaa
     4201 tcctcaaatt tcaggtgtac ctttaactct aaaagagaat ccaataatct ggattaaaaa
     4261 agctttagga agagctattg gtgtaaattt agaacctgta gacaaagaag ttttgatgag
     4321 tgaaaatcga actgaaattt caagtggtag aatcgtttct cctgagactt taaaaaaggc
     4381 aaatgaatta ggctttaatt ttatttgttt aactggaaat ccaggaacag gagtatctaa
     4441 tagaactatt gagaaagcaa taacattatc caaatcaatt tttaatggat taattatcgc
     4501 tggaaaaatg catggtgctg gtgttgatga accaattatg aacttagata tagcaaaaag
     4561 atttattaaa acaggtgtag atattttatt agttcctgct ccatacactg ttccgtattt
     4621 catggaaagt gatttgcgag gaatcgttga ttatataaaa gattttaata gaaataaatc
     4681 tattgaggaa aaagttctag tactaacggc taatggaaca agccaagact cttctgacca
     4741 agaaactatt aaaaaaattg cattagcatc aaaagcatgt ggagctgata ttcaacacat
     4801 aggggattct ttaaatggta tttgtcttcc agaaaatatt tttgctttgg gtcaagcaat
     4861 tcggggatat cgtcatcaaa ttattatgtt aggaaaatct aattatcgtt aattaaggag
     4921 gaaatgaaag atgatcgaca aagttcaaaa aatagctgca aaaattagta atcaaagaca
     4981 tctactagct ttaagagaca gcatggctgc agttatgcca ttaatcatta ttggttcctt
     5041 ttttatgtta ttagcaaatt tcccgataga aggatttaca aaatggttat ctgaaattgg
     5101 agtacaatcc tttttgaaca aagcatcaga ttcaacattt ggtattattg gattagctgt
     5161 tacctactct ttgggacaca atctagcaaa gacttatggt gtagactcat tatcagcagg
     5221 attattatct ttgagtggat atgttttact tacaccttta ttggatgcag atggttctat
     5281 aggatttcca acaaaatact ttggtacctc gggtcttttt gttggtatta ttgtagcact
     5341 tgtatctaca gaaattttcc ggtggtttgt acttaaaaat attacaatta aaatgccggc
     5401 aagcgttcca ccaaatgtaa gccgagcttt cgttgctatt attcctggct tttttgtcgt
     5461 tctactatgg tttattgttg ttgtaatttg ttataaactt ggaattgaaa atgttcatgc
     5521 tcttattgca gatacactcg caaaaccact atctttactg acgaaaactt taccaggaat
     5581 tatattggtt atacttattc aatgtttctt ttggatgttt ggtattcatg gtgcacaggt
     5641 aacggggcca ataattgaac cgttattatt gcaaaactct gatgtaaata gaattgctta
     5701 tcaagctgga aaagaacttc ctaacattat aacttatgaa ttcttatata actttgtttt
     5761 ttctggtggt gcaggttgtt tatttgcact tgccatttta acatttttct tttcaaagag
     5821 tcaggaaaat aaaactttag gtaagttatc aatcgctcca gtaagttttc aagtagcaga
     5881 gccccttcta tttgggtttc caactatatt aaatataaaa atgttaattc catttgtaac
     5941 tgcaccagta gtaacaacat taattactta tttttcaatg agtatgggat tagttgcaaa
     6001 acctgtagga gcaacaatcc catggacaac tccaccgata attgccggat ttttagcttc
     6061 tggtggacga ataagtggtg cagtgattca agtaataaca attgcaataa atgttttgat
     6121 atactatcca ttctttaaat tagatgataa tgccaagcta aaaagcgaaa aaaatgatta
     6181 gaactaccta tatgtttcta actgtagtta
//
LOCUS       DBBGSZ010000079         6173 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.085, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000079 DBBGSZ010000000
VERSION     DBBGSZ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.085"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            725..811
                     /locus_tag="ACIZE5_002689"
     CDS             725..811
                     /locus_tag="ACIZE5_002689"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGC6109784.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="ACIZE5_002690"
     CDS             complement(932..1621)
                     /locus_tag="ACIZE5_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109785.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1866..2780)
                     /locus_tag="ACIZE5_002691"
     CDS             complement(1866..2780)
                     /locus_tag="ACIZE5_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HGC6109786.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="ACIZE5_002692"
     CDS             complement(2762..3142)
                     /locus_tag="ACIZE5_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HGC6109787.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="ACIZE5_002693"
     CDS             complement(3592..3879)
                     /locus_tag="ACIZE5_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGC6109788.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="ACIZE5_002694"
     CDS             complement(3899..4123)
                     /locus_tag="ACIZE5_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HGC6109789.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="ACIZE5_002695"
     CDS             complement(4578..4748)
                     /locus_tag="ACIZE5_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109790.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="ACIZE5_002696"
     CDS             complement(4763..5296)
                     /locus_tag="ACIZE5_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HGC6109791.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..>6173)
                     /locus_tag="ACIZE5_002697"
     CDS             complement(5317..>6173)
                     /locus_tag="ACIZE5_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HGC6109792.1"
                     /translation="IVSRMREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEK
                     ILSLRFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYS
                     LQQFNELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPI
                     RQELTAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALAL
                     ADKQKEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLL
                     SDLDNLFQ"
BASE COUNT         1634 a         1152 c         1041 g         2346 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtacatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DBBGSZ010000080         5770 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.086, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000080 DBBGSZ010000000
VERSION     DBBGSZ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5770
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.086"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..301)
                     /locus_tag="ACIZE5_002698"
     CDS             complement(<1..301)
                     /locus_tag="ACIZE5_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
                     /protein_id="HGC6109793.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKY"
     gene            394..743
                     /locus_tag="ACIZE5_002699"
                     /pseudo
     CDS             394..743
                     /locus_tag="ACIZE5_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1015..1305)
                     /locus_tag="ACIZE5_002700"
     CDS             complement(1015..1305)
                     /locus_tag="ACIZE5_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109794.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1707..1943
                     /locus_tag="ACIZE5_002701"
     CDS             1707..1943
                     /locus_tag="ACIZE5_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109795.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1950..3902
                     /locus_tag="ACIZE5_002702"
     CDS             1950..3902
                     /locus_tag="ACIZE5_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HGC6109796.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3974..4471)
                     /gene="dfrG"
                     /locus_tag="ACIZE5_002703"
     CDS             complement(3974..4471)
                     /gene="dfrG"
                     /locus_tag="ACIZE5_002703"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HGC6109797.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(4798..5490)
                     /locus_tag="ACIZE5_002704"
     CDS             complement(4798..5490)
                     /locus_tag="ACIZE5_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGC6109798.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT         1894 a          997 c          917 g         1962 t
ORIGIN      
        1 catacttgca aagtaatact acaattccta acataatcgt agaatttaat aatttccata
       61 gcataaagtg tttagaaaag aacattaaga atagttctat aataattctt gaactccatg
      121 tcttataatg ttctatcgaa gcacccaaat agccaagttc atctaatcta cttgcataaa
      181 ctacgtcatc cgctctcata gtcggcatat acatattaaa gagtaaaaag ataccccaaa
      241 tccctattag taacaagatc agttctttgt tattcgttat ttttctatta tgtttgttca
      301 tttttatact ccttcttata tttcctaata gagtataaca tagctttaag cattacttaa
      361 agataactta aaagttatct tttaaatact taattgttaa ataccttatt tgatgcaaaa
      421 gaaatctacg atagtcaaca aaaaaatttt cattatatcc agaaaaattt ttcttagtta
      481 aggacctatg gattgcagta atgcagaatt cgtcgaataa actgccaaag acatacaatc
      541 atattgcttt taaaattgac gaacaagata tagattcgtt tgtctcaaaa atccaaatgt
      601 taggtttaac tgtcgaacca ggacgttctc gtgtgaaagg cgaggcttct tcaatttact
      661 tttacgacta tgataatcac ctcttcgagt tacataccgg tactctccag gaacgtttaa
      721 aatcctacaa ttccactacc tgagactagt aatgactagt ctctttttat ggcctctgat
      781 ccccccattg agcgaatact aatagggctt cgaattgatc tgttcaatct ttaagcaata
      841 tccctcaaat gagtttggaa agtttagtga ttcatcacaa atacttaaat acatgtagtt
      901 atatatagat tgaggttctt gtgagcgtat gctcgtgtgg gttcaaatcc catcgtctgc
      961 atccatcttt ccaaaacaag cggctaggac atttttgtct cagccgcttg ttttctagtt
     1021 tattctttca tcttgtcgga ccttttttct tgggtataga cttttctcat attctaccac
     1081 aattttgggt ttccctaaca catgatagga tctcacaaca aattgctttc tattattata
     1141 ataacctgta acgactaact tcatcccttc gtctacttca gctaggaagt tcaaactatg
     1201 ggaagcaatc aaacaattga ccccatttaa actgaaacgg atcaacggtc tggcactaac
     1261 ttgcaaagta cggatcttat ctactgttcc atattttttc tccataacct tcacctcaat
     1321 accattatac gaacatacat tccctttgta aagaagaaac tctgttttat ctttttgact
     1381 ttttgtctat tacctttctt aaaatcatat tggcacttcc tgcgaagatg aaggacatgt
     1441 actaaaaaaa agaggcagca gtatagattt aagtagttca gttttggagt acaaaaagtg
     1501 aaaatgtaaa cctaaatgag tatcaaattg caactgaatt tgatactcgt tttttattgt
     1561 taaatcaacg tttgttgtta atttacacca caaaatgtaa gttaaaatgt atataaaaat
     1621 gcgaacgtga aataattatt gtaggaatgc aaattggtgt gttaaaatgg ttacaattta
     1681 ctaagcaaaa aggggtgcat tttcctatgc aatttcttga gccaaaaaat aagaacgcta
     1741 agtctgtgga ttgggaaata tcagagcaag taagggtgat agttaagcaa tacgctgaat
     1801 atgcagagcg tactgaaagc gaagcagtgg atgaattctt attgaacatt ttagacgata
     1861 agaagtttat tgaatggatt gccaacaagc gaagtaataa gcggattgtt gaaaaaatgg
     1921 gtatcaaaga tagagtgggt tgatagacaa tgaccaagct taaaagatta gccacgaagg
     1981 aagatgaaat tgtagatgtt aaaattccga tttcaaacga agaattaaaa gatagggcta
     2041 aacaatatga tttattaact ccaaaacgat ttgcaacaag gtataacaaa atgttgttct
     2101 tgccaacgtc ttttaaatgg aacggttctg aatatcccat tcaatataat tactgcatca
     2161 atccgttttg ttgtaatttt gggaaagaac agcacaaatt caaagatgta aaagggaaac
     2221 caagtcgata taaaatgact ggtagttcca aagataaagg tcataaaggt atgtactgca
     2281 atgacaatcc tattggcaga ggtgtatcgc aaaactgtac agtaacccct ttatctaatt
     2341 ggtctgttgt tgaagaaatt aaacgcctta tagaaatcaa tagcatccaa gatgttgagc
     2401 cagattatca atttcataaa gaaggctgct cggaagaaga atcaacccca ttcaatgagc
     2461 cgaagcaatt ttacaaaagg gggaaaagta ggggcaaatc tcaacgctat caatgtaagg
     2521 cgtgtaagaa gttcactaat gttctaccaa aaagagaaga aaccactact tatcaccaac
     2581 aaaagaacac cattcttcca atgttcgcta agatggttgt tggaagggtt tcagtcagtc
     2641 gtacttgtga tattttagga attggagttg gaacctacta tcataagctg gagtggctgt
     2701 ataggcgttg tttggagttt ttagaacgat atgagacaca accccttcaa acaaagaaat
     2761 ttaacgagat gtggcttaat acggacaaga tgcactacta cctaaataac gtccgtaaga
     2821 aaggacaagg ttcaaagaaa tatacggggt ttgaagacct taatatgcaa acgtatatag
     2881 ttgtatctgc tgaggtctta tcaagatatg tgttccgttc tgatgttgcc tatgattgga
     2941 atatttcaat ggatgaatta aatgaagata caagaaaatt caaagaagac catctcaata
     3001 cttttagtcg taaaaatgat aggttagatt ggtcttatta tccacaagaa ccatccgcta
     3061 acgatagcga aaataggaat gcttatcttc acgaattagg gaaaattact aataggagta
     3121 gatttgtcga tggtttaaat gttgatgctc cttatactac aactgctcac tattggttaa
     3181 ttaaacaaat ggttaatgcc gacgaatggc gaatgattag tgatgatgac ttctctatta
     3241 gaaacgcctt ttatagagta ttcacgaaag aattaaggtt gagcgatgca catcatttta
     3301 tttgccaagt taacaagacg aaaagcagaa aacaatgctt aaaagaattc ggacaagcaa
     3361 aagcagaact gctcgattgg ggagatatca gaggattcaa aacaaagttt ctacggactt
     3421 tggcatctca ttatctaact gaattactaa caagtcatca attccacgaa gaggctatta
     3481 gtaaagatgg agaaagatat cgcaaatatg ccgataaccc tatcaaacat ccattagcca
     3541 ctaaggataa aggattttat tcagttgatt gtagaacgga tttatctgct ctggaaccaa
     3601 acgaaatcgc aaagatgcta ttaaatgtta atgaccattc gaccaatagc tttattcaac
     3661 agataagacg ttatatatca tctcttgaaa gaccattaac aacagctcgt ggtgataaga
     3721 agagctatat ttacgctaac ttcaatccga agtatgctca atttgcgatt acaattctaa
     3781 gaacttacta caacttttgt cgccctttta aatcagcgga taaaaaggtt ttgacacctg
     3841 ctcaaagatt agggattaca gataaacaat ttgattggaa agatataatt tatttcaaat
     3901 gacaaaaaga gcttggagta atcccaagct cttgtgcttt atctttactg ttcttcttca
     3961 attaacgcac ccgttaactc aataagtttt ttctttcata tacatgaaaa tagtagttat
     4021 acggattttt atcattcttt atcccttttt gggcaaatac ctcattccat tcctcataat
     4081 tcacttctgg aaaaaaagta tctccttcga attcatgatg tatttttgtg atgtacattt
     4141 tctcaacata agggaaaaac aaattataaa tctgttctcc tccgaaaata aaaatttctt
     4201 cttcgttttt acataactca aaaacatctt ctattgaatg aacaatttca caaccattaa
     4261 aggtaaaccc cttatctctc gtcagaataa tatttcttct gtcaggtaag gctcttccga
     4321 ttgattcaag gttcttccta cctaatatta tcggatgtcc ctttgtagta tttttaacat
     4381 attcccagtc cttgggaatc ctccaaggaa tgtcattctc tttgccaatc actctattct
     4441 tatccatcgc agcaatcaaa gaaactttca tttataacac agccttttta actaatttac
     4501 catctaattt cttatttcta tcaaaaaacc ttttctcatt atcctgcccg ttagttgaat
     4561 aagcaatttt ttctataagt tatattatca taataccaca aaatcacaaa ttttcattca
     4621 attatcattt tcaattgcat tttataaatc attttgtatg taatttggta tgtaagttaa
     4681 aatgaaaaaa gtagtccatt ttgaagtaca ttttgtcatt ttgtactcca aaactgaact
     4741 acttagtata gattactgtt gcttctttac taatttaggt ttacttgtta agaaagatta
     4801 tttacgcaaa tgttcttcaa caatttgctg agatttatca gctgtatctt ccacttcatc
     4861 ttttgctttt tctaactttt gaatatattg tttcaagctt gagttttcag cagttgcttc
     4921 gtctaatttc ttttgtgtat ctgttaactg agtttctaca tttgtttttt cttgtgtcag
     4981 tgttgcgatt tgttgattca aaccatttac agtattttgt aattctgaaa gttttgcttg
     5041 tgcttcttgt agtcttgctg tccaatctgc attcagatga ttgatttcat catttttttg
     5101 gttgatctca tctagtttga cattgatttc attttgtttg ctttgtagtt gtgcatcctt
     5161 gctgactaat tgactttcta agttttgttt ttctgctgcc gattgatttt tttggttttc
     5221 taattcattt acttttgttt ggtattcttg gacatctgcc tttgaatctt gcaatgtctg
     5281 ttctttttgt gctagtcgag cggtaagatc tgtaatcgct tgctctttat ctgtcaatgt
     5341 atgatcaagc tgtgtcagat tctcattgat tgtatcaata tctgtctctc caccccacaa
     5401 aataatttca tttgcgtacc gcgtgcctgt gtagccaatt agacatagaa atgcaacgac
     5461 aatcccacca gtaataaatt tctttttcat ttgcatagct ccttaatcca atacttttac
     5521 atgctaaaag taagtgatct caaacacaat gtcaagcgtt tttaaattac atatgtaatt
     5581 ttaatataaa tactatcaaa tactcattta atcctccttt tttatctatt taaaaaatct
     5641 tttttataga gaaaaatgca ggttaatact ttcttaaata aatatttatg gtgaacaaaa
     5701 acaaaaaagc aagttttatt aaacgtaacc cttttcattt catagattac tgtatttatt
     5761 acaaaaaacg
//
LOCUS       DBBGSZ010000081         5724 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.087, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000081 DBBGSZ010000000
VERSION     DBBGSZ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5724
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.087"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            193..918
                     /locus_tag="ACIZE5_002705"
     CDS             193..918
                     /locus_tag="ACIZE5_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109799.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            908..1417
                     /locus_tag="ACIZE5_002706"
     CDS             908..1417
                     /locus_tag="ACIZE5_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109800.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(1487..2935)
                     /locus_tag="ACIZE5_002707"
     CDS             complement(1487..2935)
                     /locus_tag="ACIZE5_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC6109801.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(2935..3651)
                     /locus_tag="ACIZE5_002708"
     CDS             complement(2935..3651)
                     /locus_tag="ACIZE5_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HGC6109802.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            complement(3632..3982)
                     /locus_tag="ACIZE5_002709"
     CDS             complement(3632..3982)
                     /locus_tag="ACIZE5_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HGC6109803.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            4126..4899
                     /locus_tag="ACIZE5_002710"
     CDS             4126..4899
                     /locus_tag="ACIZE5_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC6109804.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            5070..5436
                     /gene="ssrA"
                     /locus_tag="ACIZE5_002711"
     tmRNA           5070..5436
                     /gene="ssrA"
                     /locus_tag="ACIZE5_002711"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         1659 a         1124 c          994 g         1947 t
ORIGIN      
        1 attattgtcg ctgctcctct tttcgaataa acagtgttca aaagcttgca tctacggtaa
       61 tagaataggg cagcttcttc acaacctctt gctttttaca aaatattttc tggttttaat
      121 tcgtgatttc actaaaggaa tttcatactt tattcatatt cattttctat actttttata
      181 gaggtgaaaa gtatgaaaat aatccgctat gctactgctc gattaattta ttacaaaaag
      241 cagacaatac tctattgttt attttcaagc ttttctgctt ttttattgat agcatgcctg
      301 actctttacc attcgcaatc ggctttagcc aatcaagtcc aagatcggct ttcatttatt
      361 ggcgcttctg catctacaga gcttcttccg gctttagaat tagctagccg attttatata
      421 aaaggcatat tcagtttatt ttttctattt gccttccttt ttatcttttt cttttactat
      481 tcagtcaggc aaaacaagca ggaattgatc aattggcgcc tgactggtct ttctaaaacc
      541 aaattattcc tttttatttt ctggcagctg ttctttcctc tctttctttg ttgtatcttg
      601 gttttattgt ggatcgtcag cttccagtca gtttatgaag cgcttcttca aaggatcaat
      661 tttcttgtct taaagactac tgaactgcca gatatccgtg atatcttgac ttcggtaagc
      721 ggacttacaa ttccgatgga tcaacagact ttttttacca tcgatttcca aaatgatctt
      781 tttttcacag atatacttaa gggatttgcc caaactctta ttgggctcag tggatgctgt
      841 ctcattctta gtctattccc tttcactttt tttatccatc atttgcaaag taggaggcct
      901 ggacgtaatg aaacctgaat atttgattca tgctgaacac ttgaccgtta ttttgtgtcc
      961 tctcgaaaaa cagcataaaa tattggagca cttgaaaaaa gaggttcttg ttgcaaaact
     1021 ggataatttt gcgatcatcc aaaaaaattg gccgatgttt ccttatctga atcttaaaga
     1081 ccatgtcctg ttggatgtac cggaaaaaga aatcaaacaa gatcgtttgg cctatcaaga
     1141 aaaacttgat atctctcctt ccttgcttaa ttgtgcggca gctgagttga cgtcttttga
     1201 aaaagtaaag ctgcaattac ttcatgcctt gctttccaag cgaaacaata ttgttattga
     1261 agatacattt gatgaactta gtgtattgga gatccaagag ctactccact tgctttctta
     1321 tttagctcat gaagaaaatc aaggtatctt actctttact catgatgcta ctattgctca
     1381 aagtccttat attgatcgtt tagagcccgc gggctaaatc aatcatttta tagtaaaaac
     1441 aagcggtata gaagatcgat tcatgatctt ttataccgct tgttttttac tcttttttga
     1501 tttctacgtc aggcaaacga acagcgaatt ttgttccttt tcctagttcg ctttctactt
     1561 ctaattttcc tttatgcaag cgtacaagtt gctgcacgat tggtaaacct aatcctgatt
     1621 caccatattt tgtatttttt cttgaaggat ctactttata ataacgatcc cagatacttt
     1681 tcatttgttg ttcagacatt ccaattcccg tatcttcaat cgtgatgatc gtttcaagat
     1741 agcctttttc taaagtaatc gtgatttggc cgttttcagt aaactgtatc gcgttttgaa
     1801 taatattgac catgatttgg acaaatcggt cataatcagc gtaaacatca atatcatcaa
     1861 cggctttcaa tgtcaatgta tctcctgctg cttctgcttt agcttctaac tgtgcaacaa
     1921 tatttttcaa tgtttctgtt ccattgaatt ttttaatgac catactgatt tgattcgtac
     1981 ggattttttc ataatccaag ttttcattca ccaaacggat cagacgctct gtttcatttt
     2041 tcatcaattt aatcgcgttt tctcgctgat tttcagggat tgcattgtat tctaaccctt
     2101 ccagaagtcc gttgattgtc gtaagaggtg ttctcatctc gtgagaagca tctgccataa
     2161 attgtcttcg acgattttct tgttcttcaa tttctgcttg agattctttc aatgaattcg
     2221 tcattttatt gaaatcatct gctaactcat caaattcatc tttgtcatgt acggggagct
     2281 gtacatcaaa attaccattc gtcacttctt tcgtcgcatt ccttaaccga ttgatacgct
     2341 taacttggaa tgctgcaaaa gcatagctgg caataactgc aacgatactg gaaaaaataa
     2401 atcctttgaa caggttcagt gtaattggac gaacgctgtt atcgatattt cgcgcaggtt
     2461 gactaactac aagtgctcca tagaattcat gattcaaatt aaatggcaca agtgcgtaag
     2521 aggtcgcctg tgcttgtcct aaaatatttt tattcgatgt gaatttttct tgacgtccat
     2581 tcctcagatt tttccattga tcagctgtta aggtaaaatt cagtaaagct gtattagtcg
     2641 gataaatgac acgttcgttt ttatcgataa atataaagtt cacattttgt tctgtcagta
     2701 cttgctctgt cagcagcaat gcattttgaa acgcctgatc ttgactaaac tgcgggagcg
     2761 tatcggcata ggtttgcgtt gtcttttcaa ctgattcagc atatccaaac agttgctggt
     2821 aattgttttc ttcaatcgtt tgttttgtca gttgtgtaaa agaaactcca acgatcaata
     2881 agatcaacgc gaccattccg caaaaagcta agagttgctg atacaaataa cgcattaggc
     2941 aacaccagaa tcatcgaatt tgtagccgac tccccaaaca gtttggatga cttgtggtcc
     3001 gaccttttcg attttttgtc gtaatttctt gatatgggcg tccactgtcc gttcatcacc
     3061 aaagtactga taatcccaga ctaattcaag caactgctcc cgagagaata cttgacgtgg
     3121 tttttttgct aaagtaaaca atagatcgaa ctctttaggc gtcagtcctt caattggccg
     3181 gttgtccaga tacgcttctc gtgttttcgt attcatcttg aaatgactag tctcgatatc
     3241 aaaatgatca tctgaaactg ctgcttcttc tcttgcttct gccaactcac tacggcgatg
     3301 caaagctttc attcgagcaa taagcgtcag aggactgaaa ggttttgtga cataatcatc
     3361 tgcccccatc tctaagccga tcacctgatc gctttcagaa tctctagctg tcagcatgat
     3421 aatcggcaca gtacttgaaa ctttgcggat ctctcttcct actagcatac cgtccagtgt
     3481 gggcaaattc aggtctagtg taatcatatc ccaatgttgt gggttttcta aaaaggcatc
     3541 gagcccttct tttccatcat acttgaaagt tgcttcccaa ccttcattta agaaaaacat
     3601 ctgcatcatt tcagaaacag attgattatc ttcaatcatt aaaatattca ttatcgttcc
     3661 ctccagtttc caggtcatat ttctgtaatt tcttttctgt cataataaaa ataggcataa
     3721 ttggaaatac tagcagaagc atttcaatca gaaaataatt cgtatgccca gatgtcttta
     3781 aataatagcc gatcaatgcc atcagtaagc ccataagaaa aaaccagttt ccgcttgtct
     3841 tttgagccag ccgccaatga gcgtctgttt ttgcggcaag aggcgaatga tacccataaa
     3901 aaggcagatt tccttttgag ggcagaatcc gaaaaagact gccaattatt aagaataaga
     3961 taccaatact gaaaaaaatc attctttccc tcctaaattc tcttcttata gtatactcta
     4021 aattgttgac tgaaccaata tgttcaggaa ttcttcacga aaggtttgtc ttttgttcat
     4081 tctttgttaa gataaactta ttccaataaa aaaggagttt tatttgtgtc aaattatcgt
     4141 gcaatcactt tctttgatct tgatggaaca ttactagatg cgaaatcaaa aatcacaccc
     4201 gaagtggcaa aagctatgaa cgcattaaaa gaaaacaatg ttctccccgt catcgctaca
     4261 ggacgtacag aagcagaaat ccactctatc atggaagatg cgggcattac ttctgcggtc
     4321 accatgaatg gttctttcat tcgagtagac ggcgaagaaa tctattctca aacattttct
     4381 tcagaagaat gtcaaaaaat gtatgatcat gtacagttga acggtcatga actttcttac
     4441 tataacgatc agaaaatctg gtgtaccggt catagccaaa caatgatcaa tgcttacgac
     4501 ttcattcatt cagatgttcc ggaaattgat cctttaggct ttaaagaaaa cacagtaaat
     4561 atgttgctga tcttatctca atcaggtgac gaatactatc acgaacattt tcctgagcta
     4621 actttttatc ggaatggtcc ttactcgatc gatacagtga agaaaggaat ctcaaaaggg
     4681 gcaggtgtca aacgtctgca aaaagaactt cagctggaaa aagttcctac ttttggattt
     4741 ggcgatggtc cgaatgattt tgccttgttg gaagcttgcg acaacaaaat cgctatggac
     4801 aacgcctatg acggattaaa agaactttct acctttatca caaagaaaaa tacagaaggc
     4861 ggaattgtcc acgcattgaa gtattttgat ctgatttaag atcttttttt gaagctacct
     4921 cttttcttaa gaaaatcgct tattttttct taagaaaggg gcagttatta tataaataat
     4981 gggatatgat tcgctttttt attgaattta tcccaatata tgctatacta attttgtatg
     5041 aaaaatacac gtaacccttg ttagctaacg gggacgttac ggattcgaca ggcacagtcg
     5101 agcttgaatt gcgtttcgta ggttacgtct acgtaaaaac gttacagtta aatataactg
     5161 ctaaaaacga aaacaactct tacgctttag ctgcctaaaa acagttagcg tagatcctct
     5221 cggcatcgcc catgtgctcg agtaagggtc ctaactttag tgggatacgt ttcaactttc
     5281 cgtctgtaag ttgaaaaaga gaacatcaga ctagcgatac agaatgcctg tcactcggca
     5341 agctgtaaag tgaatcctta aatgagttga ctatgaacgt agatttttaa gtggcgatgt
     5401 gtttggacgc gggttcgact cccgccgtct ccatatatgt atggttgaga cagataaaca
     5461 tgtatgaaaa acgttgttaa atcaacgttt ttttattttg gtcaaggaga gaaaagtaga
     5521 gaaatacaaa attttttgca ttgattttgc attcaaaaaa acattcaaac atttagaaat
     5581 ccccaatacg tattcaggaa aatctatttt aaggtttaca aaaagaactt ttgttcgtac
     5641 actctttttg aggtgaactt ttatgctgat ggaaggaaaa acacaattat ggtttaagca
     5701 tgttccttca aataagtttt ttta
//
LOCUS       DBBGSZ010000082         5341 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.088, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000082 DBBGSZ010000000
VERSION     DBBGSZ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.088"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(62..286)
                     /locus_tag="ACIZE5_002712"
                     /pseudo
     CDS             complement(62..286)
                     /locus_tag="ACIZE5_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877485.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(840..926)
                     /locus_tag="ACIZE5_002713"
                     /pseudo
     CDS             complement(840..926)
                     /locus_tag="ACIZE5_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            2092..3132
                     /locus_tag="ACIZE5_002714"
     CDS             2092..3132
                     /locus_tag="ACIZE5_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HGC6109805.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            3956..4288
                     /gene="traE"
                     /locus_tag="ACIZE5_002715"
     CDS             3956..4288
                     /gene="traE"
                     /locus_tag="ACIZE5_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HGC6109806.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4907..5248
                     /locus_tag="ACIZE5_002716"
     CDS             4907..5248
                     /locus_tag="ACIZE5_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HGC6109807.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1943 a          728 c          900 g         1770 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aaccgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccacttgcag atgtagtgtg cagttacctc tgcaaatggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa accccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattata ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt agtacttaaa caatctaaaa aatagttatc ccaattgtta tgcttttata
     1081 atacgattat ttgtaacaaa atgaatatta tataattaaa cactaccata tttaggtagt
     1141 gtttaattat tagcaaaaca aaaaatattt attctattct cttaacttca actaagttat
     1201 gctgcacacc tttatataaa tcatatgcaa ctcattagct agacaaacta caagcatgta
     1261 gttttatctg ttaattatgt actacctaaa taaagtagtt tataattagc aagtatatat
     1321 atttaaaaat ttaagattaa tttttttatg acttgtacaa atttatctga tattctctta
     1381 ttaagaacta cctaatttgg gtagttctta ttttttacat tttaagtagt atttaattgc
     1441 aatttggtag tattttttta ttatcttatt cttagaacgg tagtacttaa tataaatata
     1501 ggtagtatct aatttaagta ttaatggtag tatctaaatt aacaggtagt atgtaactac
     1561 tttaaagtaa tttttttcag attaacacag tagtatctta ttaaataagt taattttaat
     1621 ggtagtacat aattattata tatatctgac attggtagta cttattgtat tttttagtag
     1681 tatataatct attgttttct agcctaaagc cttgtcttat aagaataata taatatatac
     1741 tactgaaata aggtagtata tattactagt aatggtagta tgttttatat gcataaggta
     1801 gttcttaatt tattttttgt tttgacactg gtagtactta attatcttta attttaaaac
     1861 taaattttat tcatacgttt ttctggtagt atttaattat aaataatatt tatttaaagt
     1921 agttcttaat gactttaaag gtagtacata attcatttta tttctgattt taggtagtat
     1981 ttaattaaaa aacagtttta atgcgtttgc attttttatt tatctttgct attttcgaaa
     2041 agagtaggta attttacata aataaaacaa cgtgaaagta gaggatctac aatgactgat
     2101 tttaaatttt ttaaggcgga tagagtttac aacgaattat tttatcaatt tccaaaagtc
     2161 tttattgttt ctgacgaata caaaaaaatg aaagattcaa ctaagattgc ctatatgctt
     2221 ttaaaagcaa gattagagat cgcaatcagc aaacggcaaa tcgatgaaga aggtaatgtt
     2281 tattttactt atacgacaaa tgaactatgt agagtattaa actgccaaaa acaaaaagcg
     2341 atagcaatca aaaaagagtt ggaatccttt ggtttattat tacaaaagca gatgggattt
     2401 aacaaacagt tagggaaaaa taatcctaat agactatatc tagcagaatt aaaagtctca
     2461 gaaaatgata tctacttact cgaaaaattt gatagagaga atagggaaaa cgttgataaa
     2521 tcagagggta tgaaaatcat acccaccctc gacgaaaaat cagacgctga atcccttggg
     2581 gctcaagagg gtatgaaaat cataccgtgc caaaacgttg ataaatcaga gggtatgaaa
     2641 atcataccag aacttaataa taatatatta gacactaata gacacaatat agacactgaa
     2701 aaagaccgcc tacaagatca attgttgtta gacaattttg agacaattat gacaaacgac
     2761 agcattgcta cgtttgtccc tgaacgagta ttaaatttga taaaaacatt ttcttcaagt
     2821 tacagtgaag ctcaaaaaac cgtccagact attcataatg caaagaaaaa agctgaaata
     2881 gaaagtgata tttcgatagt ttttgaagaa ctcgatagtt attatgtcaa tgcagaacaa
     2941 gaattataca cgacactgtt aaaagcctat caaaaattaa aaaccgaaaa agtcgaaaat
     3001 atccagaacc tgatttttgt ctatgtaaaa aattggttta tcgaaaaacc aatagctgct
     3061 aaagtatcaa gtgaaaaacg tttgaattat gcaagctccc caagcactat tacgaaagac
     3121 tggttagagt gaaactttac tgacaaagtg attgttgctt catggagtaa cattaaaatt
     3181 aaaaattttt tattattcta attatattac gaatattaca aaataatagc tattttaata
     3241 gaatttataa gttaaaatat tatgataaaa atcacaaacg tagcctttta cgtcataagt
     3301 gttaaaagaa ataattaatt tcaaatatag aaaagggaac gtatgtttgc atactccttt
     3361 tttttgagtt ataataatac gcgaagagag ataatttcat tatttaaaca agctaaaaat
     3421 cttgatatta cttcttttca ggcaatacga atattattcg cttacatttt ttgtataaat
     3481 ttaattgtct gctatgcttg tgatgaattg attttcgttt tgcacttttg gatgataaat
     3541 ttggacaatt gaaaatacaa aaaaaagaaa ggcggtatga actcggaagg ctggtaacct
     3601 tcgtcagcgt tcatacacgg cattaagatt tggcccttaa tgcgttaacc tttcagtgtt
     3661 acggtattac ccgcaatgga tttagtataa cagatattca aaagtgatac cacttttttt
     3721 ggctgtgtta aggttaaaaa tacgtgatat tacgatgaat ctatgcctaa gcataatgtt
     3781 ataaaaatgt ccgtgtggct ctttgccgta tgacgaacgc tgaaattaga gggaacgcat
     3841 gtttggatgc gttccctctt ttttgtttgt catgaacgaa aatcaattct ctatttttga
     3901 aaaataacaa gaaaaacttg ttaaaaatat ttaaagaaat tgggtggttt attttatgtc
     3961 atatacagga attttgagtc tcaaagatat ttgtcactac ggtaaacggt gtaccgctac
     4021 agagaaaatc acgaagaaac tatcaactgg ccaaagtaaa accgttgtgc agtgtaagaa
     4081 atatataatc cagaaagaca aagtctcaga ggaaatgatt tattacattg ggaaacaaaa
     4141 gcaaataatt ttaaaagatc ctatcccctt aaaagagcta tatccaacaa tcaaacatgt
     4201 ttatgaccaa aacggtgtac tgattggtcg aagaaaaaat ggagtcttgc gttgtaccgc
     4261 aaaagggatg gggcgtttga tcggctgaat tgatcattct cataacttgt attttatcgt
     4321 ttttcgcttg cttgaaaata ttgtcgagac ttctaaagga acttagagtc actagaaaaa
     4381 taaggagtag acttgatcta tcaacaattc ccttcgggga gtgacggggt aggttttaac
     4441 gattggtaac gtaaaaaatt ggtcaatcga gtaaatgcgc ttgtttggat agtggtgaaa
     4501 tgaatttgtg taaataataa gcgcagagta aacaagaggg aatttagaag ttagacaagt
     4561 tagaatagcg tctagattaa tcatgagcag ctactaaggg atctagactt tgacgcaaac
     4621 tcatggaata aggagtaggt cttctcgtaa tggggaggac gcacaagaaa ttgtgtcgtg
     4681 tgctgcagta catgtagata cttgcgagga cgttgattat tggatcaatc gagcatttac
     4741 cgctgtctac tagggtttct cgtttcggac gccataaacg agtcgaaatt ttttatgtat
     4801 ttttaagtaa acgaaaaacg ataaaatatg aacaagtcct gaataaagtg aaaaaattaa
     4861 tataaagcat agagaaaatg aaatttacgt aatggaggaa tgacaaatga aaaattatga
     4921 tccgaatata cgattgggca cacatactat taaggtttct ttccaacgtt gggattacaa
     4981 aggatttgtg acgtttagaa ggggcggaaa ttgtaaagga ttagatgttt tagcattaga
     5041 cgaggatgat ttatacgatc aaacattgac tgataatcca attggattcg gcttgctacc
     5101 tgaagatgat gaaggtaatg aatggtttaa aatgacgctt atgaatgata atggagacga
     5161 attatctgtt gaagatactt ggtcatattt gagtgattat attgtcagct ttgaaatcat
     5221 tgaatttgta gcggataaag aagaataaaa actggaggaa taaattttac agataaaggc
     5281 ttagaaggag tcacgacgat taataaaaag gtagtattac cttaggcatt gagtaaggaa
     5341 t
//
LOCUS       DBBGSZ010000083         5339 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.089, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000083 DBBGSZ010000000
VERSION     DBBGSZ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5339
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.089"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(19..414)
                     /locus_tag="ACIZE5_002717"
     CDS             complement(19..414)
                     /locus_tag="ACIZE5_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109808.1"
                     /translation="MKNKGQIWYIGYIVSLFLIVTILVTDFPKMVDIGLAILFSAVFG
                     VSHVQILHDKMIKNDADYKINVMDERNIIIKEKAGNITNMFNTILLGVATVIFICLDY
                     IIPAIIVGSIIAIQPIILIIISSVLEKKM"
     gene            complement(404..616)
                     /locus_tag="ACIZE5_002718"
     CDS             complement(404..616)
                     /locus_tag="ACIZE5_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6109809.1"
                     /translation="MKNRLEELRKQRGIKQEDLASALEVSRQTIGSLENGRYNPSIIL
                     AFKIARYFQMSIEEIFIYEEESEDEK"
     gene            1688..2290
                     /locus_tag="ACIZE5_002719"
     CDS             1688..2290
                     /locus_tag="ACIZE5_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbiJ-NTD4 domain-containing protein"
                     /protein_id="HGC6109810.1"
                     /translation="MEDIILRDRLTDPLKNSLANVIYDILREADKVYSNYNGKVSWVI
                     YSFLIKEFFKEQINNSYELGYHFTVYYEDIIKRLEDLEWYAYYDLLEVFASAKILDKK
                     KREEVNKILESENSGYRLSESNEFIPITDDISIKSINAVSESPFNYAKNHIHKSLTYI
                     SEKENQDYNTVVREAISAVESCLIEFSGLPANKKILWELL"
     gene            2645..2881
                     /locus_tag="ACIZE5_002720"
     CDS             2645..2881
                     /locus_tag="ACIZE5_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HGC6109811.1"
                     /translation="MNIKKRKIREVGNSIVVTLSKESLLQKGLKPGDTIFIDEDKMME
                     AIVKEESKIDLEIDMYVNQALSEYDAAFKELVEK"
     gene            2878..3291
                     /locus_tag="ACIZE5_002721"
     CDS             2878..3291
                     /locus_tag="ACIZE5_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HGC6109812.1"
                     /translation="MIYLSEKDIVKLNVIQIKKYSPRETIGVIDKNALSMAVNQPKQH
                     IFGKDLYPDKFSKAAVLLINLIKKHPFHNANKRTAFLAAYVFLKLNGYSLKMKNQEVV
                     EFVVEIATYQGDFDDLKEATTDILKKNSTKTDSKK"
     gene            3834..4760
                     /locus_tag="ACIZE5_002722"
     CDS             3834..4760
                     /locus_tag="ACIZE5_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003953 - NAD+ nucleosidase activity
                     [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HGC6109813.1"
                     /translation="MTGRNPKVFISYSWENKENKEWARELADKLLENGIDAYIDQYDL
                     SLGDRLPQFMEQQISDSDYVLIICTPEYKKKANNRTSGVGYEGHIISAELLSGKNERK
                     FIPIIKEGRASEVLPTFLAGKLGIDLSDSQHYDENLDDLITTIFGVKRKPALGDIPRH
                     IKGSPLLPIEHNENKDIEILGIITDKVTVPKMDGSRGSALYKIPFRLNRVPSQLWKEL
                     FVRNWNSPPRYTTMHRPGIASVVDDEILLNGTTIEEVREYHRETLKLCIEKSNTQEKK
                     ILLEEEQKKERENERVRSHKESVQKLADELEF"
     gene            complement(4757..>5339)
                     /locus_tag="ACIZE5_002723"
     CDS             complement(4757..>5339)
                     /locus_tag="ACIZE5_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6109814.1"
                     /translation="SIDQNEQRQIEEMRKFGAEKIFIEKQSGATITHRPIFQEVLDFV
                     RDQDIFIVEAIDRLGRNYDEIIDSVNYLKKKNVRLIITNLPIMAEAIGNPLLDKFIKD
                     LIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANTKDPQRRLVYRSIV
                     QDQENGVAISKIATDYNVTRQTVYRIKKELTIN"
BASE COUNT         1908 a          760 c          902 g         1769 t
ORIGIN      
        1 ttgtatgaac ctttatttct acattttttt ctcaagcaca ctactgataa tgattaaaat
       61 aatcggctgg attgcaatga tacttccgac aataatagct ggaatgatgt agtctaaaca
      121 aataaatata actgttgcca cccctaacag tattgtgtta aacatatttg ttatatttcc
      181 cgctttttct ttgattatga tattccgttc gtccataaca ttgattttgt agtctgcatc
      241 atttttaatc attttatcat gcaaaatttg aacatgagaa acgccaaaaa cggcactgaa
      301 taaaatagca agtccaatat ctaccatttt aggaaaatct gtaaccaaaa ttgtcacaat
      361 caaaaacaac gaaacaatat aaccgatata ccaaatctga cccttatttt tcatcttcac
      421 tttcctcctc atagataaaa atttcttcaa tgctcatttg aaagtacctt gcaattttaa
      481 atgccaatat aatagaggga ttataacgtc cattttctaa agaacctatt gtttgacgag
      541 atacttcaag agcagaagct aaatcttctt gtttaattcc tctttgtttt cgtaattctt
      601 ccaaacgatt tttcacaaca tgctcctttc taaaaaatgg aaagtttact ttcctttcgt
      661 gcttttataa tactcctgcg agcacaaaat gtcaaggaag ctttccatat aaattttgat
      721 tttaatgttt tagttactgt ttttatgaca catgaacaca cttattctta tttcctctta
      781 tctgctatca acagaaaaga aaaagccctg tcaagagccg attagatcaa gccagtcgag
      841 aaacgatgtt agaccaaatt gattttgggt aatgaatgtt tagaacttag tagtcatcca
      901 aaaacgacta ctttttttgt tgaatcgtcc aaggacgatt cgatgctttt gacttgtaag
      961 aacaggattg aatgaaacca tactgttcgc atatttttag tggatgaaca aacaaaatac
     1021 gagagatttt ttgttcgttc atccatggtt ttagaaaaaa gagggacgat tttggaagaa
     1081 gaaaatcgtc tctttttttt cttctttttg tatgacaaaa agaaagatct tttgcccatt
     1141 ttatttttat aaaatgggta ggtggcgttc gcgtaaagca aatcgataca atccaatggt
     1201 tttggcgaat cagatttacc attctaggct tgtttaatac agacatcgat tgttattttg
     1261 agaatttata tccttattgg caatgaaatg gatattctcc ataccaatag aaatcttcaa
     1321 gataattttc ggaaatatat aagagttaat caattatgat catatagtag gtaaaaatta
     1381 ggacagcctt caattatatg ggaaaccaat ataatcaagt aattattcgg gtaacacaaa
     1441 tactagagta ctcatttctt ataactgttt tacacctatt agggatcagt attattaata
     1501 gatctagata aattaatacg taattatata ataatttatg tttgtgccat taaacaatct
     1561 taacagatat ttcattttat ttatgtaaaa caacacgaat aattattgct tcgtaaagtt
     1621 atatgagtat aagttaattt actggaggta gtgcaatgct tttttctgaa agatttggtt
     1681 ttaaaaaatg gaggatatca tactgagaga tagattgaca gaccctctta aaaatagttt
     1741 agcaaatgtg atttatgata tattacgaga ggctgataaa gtttatagta attataatgg
     1801 aaaagtctca tgggtaatat attctttttt aattaaagag ttttttaaag aacagataaa
     1861 taatagctat gagttgggtt atcattttac tgtttattat gaagatatta tcaagaggtt
     1921 agaagacttg gagtggtatg cttattatga tttattagag gtttttgcaa gtgctaaaat
     1981 cttggataaa aagaaaagag aggaagtaaa taaaattctg gagtcggaaa attctggtta
     2041 cagattaagc gaaagcaatg aatttattcc aatcacagat gatatttcta ttaagtctat
     2101 aaatgctgta tctgaatcac catttaatta cgcaaaaaat catatccata aatctcttac
     2161 atatataagc gagaaggaaa atcaagatta taatactgta gtgagagaag caattagtgc
     2221 tgtcgaaagt tgtcttatcg aattttcagg attaccagct aataaaaaaa tactttggga
     2281 actgctataa aagcaattaa agacaaatcg aataacaatg tcgatcttac atttttaaaa
     2341 ccatttgaga caatgtatgg tttggcgagt aataatggaa tacgacatgc agaaaatgaa
     2401 aaaacaattg tctcagattt acctgatgca gttttggtgt taacaacatg ttcagccgta
     2461 attaattatt tgggagtaaa aatagcatat gactccaata aatcatgaaa agttaaaatt
     2521 catccaagag ctacattata actattaatt tccaactctt taaaagttta gtaattgaag
     2581 gaagtaataa gggtgattga acaatacgga tatacggtgt atacttatcg taggagttga
     2641 tgatatgaat attaaaaaac gcaaaatcag agaagtaggt aattcaatag ttgtaacttt
     2701 gtcaaaagag agtttattgc aaaaaggttt gaaacctgga gatactattt ttattgatga
     2761 agataaaatg atggaagcta ttgtaaaaga ggaaagcaag atagatcttg aaattgatat
     2821 gtatgttaac caagctttat ctgagtatga tgcagctttc aaggaattag ttgaaaaatg
     2881 atctatctaa gtgaaaaaga tattgtaaaa ttgaatgtta ttcaaataaa gaaatattca
     2941 ccgcgagaaa caatcggagt cattgacaaa aatgcgctga gtatggctgt aaatcaacct
     3001 aaacagcata tttttggaaa agatctgtat cctgataaat ttagcaaagc agctgttctg
     3061 ctaataaatc tgatcaaaaa gcatccattt cataatgcta acaaacgtac agcattttta
     3121 gccgcgtatg tttttctcaa gctaaatggc tattcactaa aaatgaaaaa tcaggaagta
     3181 gtagaatttg tagttgaaat tgctacgtat cagggtgatt ttgatgactt aaaagaggca
     3241 acaacagata tactaaaaaa gaattcaaca aagaccgatt caaaaaagta gaagcaaact
     3301 agggattcag ttaaatctga agatttagtt tgttctttat tttagtttac ataagataca
     3361 ttatgcgaag ttcattattt taaaagctta aataataaac ttttttataa taccaattta
     3421 tttatgtaaa ccaatgacct taatcgctta agcaagcatg ttatgtaata ctctactctc
     3481 tccaaaacta atgactatct attttcaaag aagctagaat gattatctga tcaaatgata
     3541 atttatattt aattcctggt ctactgctct tcttttaatc aattaatgtc taacgtactg
     3601 tacacgataa agtaggaaga cttattttca acttcggatt cattttttta attcggtgaa
     3661 aatcactaaa ttaagagttt atccaagttc attttagctg agaatacgct tgaaaataat
     3721 tttgatgaat tttcctgaat taaaatttat taacttgttg agtgatataa ttgtaatgta
     3781 ttaccaaata gttagcactt agattagtga tggaaaggaa tagtgagaac aagatgactg
     3841 gtagaaatcc caaagtattt atatcatatt catgggagaa taaggaaaat aaagaatggg
     3901 ctagagaact agcagacaaa ttacttgaaa acggtattga tgcatatata gatcagtatg
     3961 atttaagttt aggtgataga ttacctcagt ttatggagca gcaaatatcc gattcagatt
     4021 atgttctaat tatatgtaca ccagagtata aaaaaaaggc aaataatcgt acaagtggtg
     4081 ttgggtatga aggtcatatt atctcagcag aattgctttc tggaaaaaat gaacgtaaat
     4141 ttatcccaat aattaaagaa ggacgtgcaa gcgaagtact tcctactttt cttgctggaa
     4201 agcttggaat tgatttatca gatagccagc attatgatga aaacttagat gatttaatta
     4261 caactatatt tggtgttaag agaaaaccag cattaggtga tatacctagg catattaaag
     4321 gcagtccttt actacctata gaacataatg aaaataaaga tattgaaatc ttaggaatta
     4381 tcactgataa agtaactgta cctaaaatgg atggctcaag gggttctgca ttatataaaa
     4441 ttccatttag attaaataga gtaccaagtc agctttggaa agagttgttt gttagaaatt
     4501 ggaattcacc accacgatat acaacaatgc atagaccagg aattgcttct gttgtagacg
     4561 atgaaatttt acttaatgga acaactattg aggaagtccg ggaatatcat cgggaaactt
     4621 taaaactttg cattgaaaaa agtaatactc aagaaaaaaa aatattgcta gaggaggaac
     4681 aaaaaaaaga gagagagaat gagcgagtca gatcacataa agaaagtgtt cagaaattag
     4741 cagatgaatt agagttctag ttgatagtca gttctttctt aattcgatac acagtttgtc
     4801 tagttacatt atagtctgtt gctatttttg aaatagcaac accattctcc tggtcctgaa
     4861 cgatgcttct ataaacaagg cgacgttgag gatcttttgt gttcgcactg tataacttag
     4921 gacgtccttt atagacgccg tttgctttag caatctttat cccttgtgcc tggcgtcgtt
     4981 ttgattcagt acgctcttgt tcagcaatca tggccaagat ttgaatgatt aggtctttga
     5041 taaatttatc caggagagga tttccgattg cttcagccat gatcggtaaa ttagtgataa
     5101 taagtcgcac atttttcttc tttagataat ttactgaatc gataatctcg tcataattac
     5161 gtccaagtcg atcgatagcc tctacaataa aaatatcttg gtctctaaca aaatctagaa
     5221 cttcctgaaa aatcggtcga tgagtaatag tcgctccaga ttgtttctcg atgaaaattt
     5281 tttcagcacc aaattttctc atttcctcga tttgacgttg ttcattttga tcgatcgat
//
LOCUS       DBBGSZ010000084         5311 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.090, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000084 DBBGSZ010000000
VERSION     DBBGSZ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.090"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="ACIZE5_002724"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="ACIZE5_002724"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HGC6109815.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="ACIZE5_002725"
     CDS             complement(1297..2133)
                     /locus_tag="ACIZE5_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6109816.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="ACIZE5_002726"
     CDS             complement(2317..3534)
                     /locus_tag="ACIZE5_002726"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGC6109817.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3683..3844)
                     /locus_tag="ACIZE5_002727"
     CDS             complement(3683..3844)
                     /locus_tag="ACIZE5_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109818.1"
                     /translation="MEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGIAMDWAA
                     NLWNDYHDN"
     gene            3917..4000
                     /locus_tag="ACIZE5_002728"
     tRNA            3917..4000
                     /locus_tag="ACIZE5_002728"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..5311)
                     /locus_tag="ACIZE5_002729"
                     /pseudo
     CDS             complement(4240..5311)
                     /locus_tag="ACIZE5_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1653 a         1082 c          838 g         1738 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat
     4741 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
     4801 taaaaataag atattcatgt ctaaaaaaac ggctttccaa atgatgaaat acctaaatct
     4861 aacttattaa gaaagttgaa atttttatat tcaggaaacc atttattaat ttcatgtgca
     4921 gcacgtaatg cattccctgg agttgtcaaa gagaaaatta attctgctaa gcttattatt
     4981 gaaaatactg ataacttata attatatcgt ccattgacaa tcaaatataa actaactata
     5041 cttgttagaa caaaaaaaca ggcgttgact tgttcttgat tagttaaaaa tatcaataaa
     5101 ggaatactta cccaatatat ttttctattt atttcttctc ctcttaagag ttgaaaaaac
     5161 ggataaaaag ttagtaaact aaatgctact ggccactgat agttcaaggt ggttgctctc
     5221 caaccggttt cccccattac tgtcaatggt attaaacagt atatagagca aaccaataat
     5281 aaatttttaa catttatttt ctcaaaaaca t
//
LOCUS       DBBGSZ010000085         5122 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.091, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000085 DBBGSZ010000000
VERSION     DBBGSZ010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5122
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.091"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..286)
                     /locus_tag="ACIZE5_002730"
     CDS             complement(<1..286)
                     /locus_tag="ACIZE5_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC6109819.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVVIVAKQLKHGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIAKRSTEGWTPDVIIG"
     gene            446..1534
                     /locus_tag="ACIZE5_002731"
     CDS             446..1534
                     /locus_tag="ACIZE5_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109820.1"
                     /translation="MYSKNWKKKLVMGVMVGSIFVFAGCSASTDKSKTATSETKTAEV
                     VKSKMKQIEKNVEKILAEKDKDTKLSEYKKFVTESSAYSKSDKTEKKITNTYTESIKK
                     IKTNFKEQDDKDLKENTLDNLEEATENDLSQKVNTLDELKKWVQKESTDVYSQAEVDS
                     LIKKIDDTITTYKNQLEKIKIDNQEATSTETTTESSEVATLQENVSEEPQVVHTNLLN
                     SIEEAAQYLGQKLPQSGGSDAFENGQQNSDGSFTFHYQLHGGPEGITWNIITVNNNGE
                     IIQDDYFKTVPNEATNNNVSTLSQAAISELEAAQLAIAKHNELGRPNATDAGSETTAD
                     GYYFYYMADGTDQMYKYFVSNSGQVQAE"
     gene            complement(1991..2158)
                     /locus_tag="ACIZE5_002732"
     CDS             complement(1991..2158)
                     /locus_tag="ACIZE5_002732"
                     /inference="COORDINATES: protein motif:HMM:NF012372.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HGC6109821.1"
                     /translation="MSIREIVRIQSFPDSYIFVGSSLSAKYKVIGNAVLPKLAKVIGD
                     SIVKQLSESNF"
     gene            2203..2625
                     /locus_tag="ACIZE5_002733"
                     /pseudo
     CDS             2203..2625
                     /locus_tag="ACIZE5_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3402..3597)
                     /locus_tag="ACIZE5_002734"
                     /pseudo
     CDS             complement(3402..3597)
                     /locus_tag="ACIZE5_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
     gene            3946..5031
                     /gene="xerS"
                     /locus_tag="ACIZE5_002735"
     CDS             3946..5031
                     /gene="xerS"
                     /locus_tag="ACIZE5_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HGC6109822.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
BASE COUNT         1902 a          795 c          802 g         1623 t
ORIGIN      
        1 ggccaataat gacgtctggg gtccaacctt cagttgatct ttttgcaatg tattcttttt
       61 cctcagcagg aaaaatgatt tcggttctcc cacaacgtcg cttattttct ttgtattgtt
      121 caaagtattc aagtgctgtt ccaccacatt tgagaaagtt atagacattg taaattgttt
      181 ggcgtccatg tttaagctgc ttcgcaacga taacaaccgg agtttcttga tgaaaatatg
      241 cttctatcat tacaagctcg tttggtgtaa gatgggtata agtcatttat gttcactctc
      301 cttgtatgct ttagcgggta ttacaattgg agtgtaacat aaatggcttt tttatttgtc
      361 tcgcttaatt atacaaacgg cgtcaatata accactttta tgaaaagatg ttataattaa
      421 ctaaaaaata atagggagaa aacacatgta ctcaaagaat tggaaaaaaa agttagtgat
      481 gggtgttatg gtagggtcta tttttgtttt tgcaggttgt tcagcttcga cagacaaaag
      541 taaaacggct acttcagaaa caaaaactgc tgaagtagta aaaagtaaaa tgaaacaaat
      601 agaaaaaaat gtagagaaaa ttttagccga aaaagataaa gatacaaaac tgtcggagta
      661 caaaaaattt gttactgaat ccagtgctta ctctaagtca gataaaacgg agaaaaaaat
      721 tactaatacc tatacagaat ctattaagaa gatcaaaaca aattttaaag aacaagacga
      781 taaagactta aaagagaata cactagataa tcttgaagaa gcaactgaaa atgatctttc
      841 tcaaaaagta aatacattag atgaactcaa aaaatgggta caaaaagaga gtactgatgt
      901 atatagccaa gcggaagtag attcattaat caaaaaaatt gacgatacaa ttaccacata
      961 taaaaaccaa ctagagaaaa taaaaattga taatcaggag gctacatcaa cagagactac
     1021 aacagaaagt agtgaggtag ctactttaca agaaaatgtt tccgaagaac cacaagtggt
     1081 ccacacgaat ttattaaatt ctattgaaga agcagctcaa tatctgggac aaaaacttcc
     1141 acaatcgggc ggttcagatg catttgaaaa tgggcaacaa aattctgatg gctcgtttac
     1201 ttttcattat caactacatg gaggtccaga aggtatcact tggaatatca ttacagtgaa
     1261 taataatggt gagattatcc aagatgatta tttcaaaact gtacccaatg aagcaacaaa
     1321 caataatgtc tctacactta gtcaagcagc tatttcagag ttagaagctg ctcaacttgc
     1381 aatagctaaa cacaatgagt taggtagacc taatgcaact gatgccggaa gcgaaactac
     1441 agcagacgga tattattttt attatatggc cgatggaact gatcagatgt ataaatattt
     1501 tgtaagtaat tctggtcaag ttcaagcaga ataacattga gttataatga tattatcaga
     1561 tgaactgtat cataaatttt taacgtgaaa tgtttgtaat atcaattgga gaatggtata
     1621 tggatttact aaaagataat aactgttatt ttttagtaaa ttcatactat ttagaaaaga
     1681 ataatttgct gaatacttgt aaactatgtg tgatacttat cttatatgga tatagactcg
     1741 tggtgctagt taatttcagc ttattataaa ccaacatttt cattttataa aaacgactaa
     1801 aaacagaatt tctgagtaaa atttcaaaag taaaaatagt gatattatgc tcttgttcct
     1861 agattcaata attaactagc accacgagtt tataaaattg gcaataaaat tttaatcatt
     1921 attaacataa cctggatctg taaagcaatt taactcttaa taaaaaagca tctaaaaaaa
     1981 gcgtgttcag ctaaaagttt gattcagaaa gttgtttaac tatagaatca ccaattactt
     2041 ttgcaagttt tggtagaaca gcattaccaa ttactttata ttttgctgaa agagagctac
     2101 cgacaaaaat ataactatct ggaaatgact gaattctcac tatctctctt atcgacactc
     2161 ttagatgaac tcaaaaaaat gggtacaaaa agagaatact gatgtatata gtcaactaga
     2221 aatatcgctc atagagtgcg tgttcgaggt cgaaaagaaa tctgtgagga gttcaaattg
     2281 atttaccatg cgaattcaaa agaagaggca ttgaattaca tcgattttat gattaggaaa
     2341 tggaaaaagc aggatcgaag agtcgtgaac ctactcttga atcctgccct attaaccttt
     2401 tataatttcc cttacgctat cagacgaaca atttattcaa cgaacctgat tgaaggcttt
     2461 aataagcagc taaaacgata tactcgaaga aaagaacaat tccctaatga agaatctctc
     2521 tagagattct tagcttcgca attcaactaa tataaccaga aatttttaag tagagttcac
     2581 aaaagattta aagaaattca agatacatta gagtcgatga tttaactgta attaacagaa
     2641 tggattttcc atttacacat aattcttgac gctacctcat aataattaag agctttaaaa
     2701 ttagtattta ttagatactt aaaagctatt ttagtattga taaattgtta ccagcaacaa
     2761 aaaagaagtt acttagtgct aacttttgag caactgctag aggaggtagg atatggctaa
     2821 ttatcctgta atttttattg tattttctag aaatgtaatt attctcttaa acattccagc
     2881 atatccaagt atatagaaaa tttacgtttt ctatatagtt ggatgtttac aagttatatc
     2941 tggtttaata agtttttttc tgttagtcat ggcatgtttt attgtgctgg ttcatcaata
     3001 tattgaaatg tactaaaatg aaattttcag ttatggtata atatttatgc tgtctgctac
     3061 cccggcctat tatggcaagg ggaggaggtt gtattatgaa ttaccttttc gatatgtttt
     3121 ttgcaatctt agcagaagta tccgcgcatt acatctgtaa atggcttgat tgcaaaatta
     3181 ttgccaaaaa agacagtaag cctacccgtt aatctgaata gaacgtaaaa gaaaaccact
     3241 agcccgccag ctagtggttt ttggtgtatc atgaattacc ttttcgttaa aacaattata
     3301 ccatatttcc taaaaaatac aattaataga cgaattatca ttaccacttt gatgaaaaaa
     3361 gctgacataa atttttcttt tatttttata atgaataaac atttatcaat aagcttttga
     3421 aaggcaggat cgtactttgt tgatgattga gatattgcta catcaatctc agcagttaag
     3481 atttttttga attgttgctt gaattttttc tttatctaaa aaaattgtat ctccaggatg
     3541 caacccattt tctttaagaa attcctttta aattgttaat actactgagt gccccacttc
     3601 tctgaatttt ctttaacttc tccctcccct tttttatttg tatatacatt catatacgct
     3661 tgttaatatc aaatcaaccg tagtctctct tatgtctaat tatatagaaa gattgttctt
     3721 tctatataat ttagacaatt taaaaaatta agattgcctc cttctgtttc ctttcctatt
     3781 catgtatacc atttatttta aattattaaa tctataccta tttatctgct tttttgaaat
     3841 aaattaataa atttcagagt ataccaattg acaaaacact ctataattgg tatagtccaa
     3901 ttatagagat actcctctcc cctacttatc gaaaggatga ataacatgaa aaatacagaa
     3961 atatatcaaa aaatagatac aatcatactt catatgcccg attatataaa agattttgtt
     4021 caagatcgtg aggataaaga tcaatcacct cgaactactt tagaatatct aaaaaattat
     4081 aagctctttt atgaatggct tctgagtgag tctatcgttc ccgatacttc aatcacctcg
     4141 ataagacagt taactgccta tgatctaaac ttgtacaaat ctcatttgaa acgtcgcaca
     4201 aaggaaaatg taaaaaaaga gacaacaaaa actaagctca aagataataa taacttaggt
     4261 ctatctactt ctactatcaa tagaaatatc acagcattaa aggttctatt taaatatctt
     4321 tcgaaaagtt ccaataatcc tttaggaaaa ccatacttag aaaataatcc tatggatcaa
     4381 gtagcaacta tcacagataa aactacgtta gctgcccgtg caaacgcaat cgagaaaaaa
     4441 ttatttctag acgaagatac acaaaattat ctagattata ttgccaatga atataaaaaa
     4501 actttgagca aacgagcttt gatctattat caacgagatg tagaaagaga cctggcgatc
     4561 aatgcattga ttttaggatc tggattaaga ctctccgagg ttgtaaatat taatttagag
     4621 gacctatctt tagaaaagaa taatgtggta gtaactagaa aaggaaataa gagagacgca
     4681 gtaaatatag cagcatttgc aatggaatat ttagctaatt atctagctat tcggaaagaa
     4741 cgatacaaag taacagaaaa cgaaaaagct ttatttctag caatttatca aggagaagcc
     4801 aagcgtatat ccggtattgc aatcgaacgg atggtagcaa aatattcaaa aggattcaga
     4861 gtccaagtca gtccacataa attacgtcat actttggcta ctagactcta tcaacagaca
     4921 aattcattgg tattaactgc ccaacaattg ggacatacaa gtacaaatac aacaacttta
     4981 tatactcata tagacaatgc agctacaatt gatgctttga acgctttgta aatgtagtaa
     5041 aaaatagtat aataatgaag cctgtctcta aaattagata aaagcccaac tttaaaggca
     5101 agcttcatta tcatttttat at
//
LOCUS       DBBGSZ010000086         4932 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.092, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000086 DBBGSZ010000000
VERSION     DBBGSZ010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4932
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.092"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            85..972
                     /locus_tag="ACIZE5_002736"
     CDS             85..972
                     /locus_tag="ACIZE5_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HGC6109823.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="ACIZE5_002737"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="ACIZE5_002737"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HGC6109824.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="ACIZE5_002738"
     CDS             2274..2720
                     /locus_tag="ACIZE5_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HGC6109825.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="ACIZE5_002739"
     CDS             2993..4345
                     /locus_tag="ACIZE5_002739"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HGC6109826.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="ACIZE5_002740"
     CDS             4516..4803
                     /locus_tag="ACIZE5_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HGC6109827.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1694 a          813 c         1031 g         1394 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 agcggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt tt
//
LOCUS       DBBGSZ010000087         4591 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.093, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000087 DBBGSZ010000000
VERSION     DBBGSZ010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4591
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.093"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            151..957
                     /locus_tag="ACIZE5_002741"
     CDS             151..957
                     /locus_tag="ACIZE5_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HGC6109828.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            975..1655
                     /locus_tag="ACIZE5_002742"
     CDS             975..1655
                     /locus_tag="ACIZE5_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HGC6109829.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGETF
                     SFWWLVRHADKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGH
                     EVKEFPEPNSDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVFADKEP
                     QALYKITNGSIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPES
                     VDIQEENQ"
     gene            1652..2623
                     /locus_tag="ACIZE5_002743"
     CDS             1652..2623
                     /locus_tag="ACIZE5_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HGC6109830.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVSHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            2616..3644
                     /gene="vanB"
                     /locus_tag="ACIZE5_002744"
     CDS             2616..3644
                     /gene="vanB"
                     /locus_tag="ACIZE5_002744"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HGC6109831.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKAAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            3650..4258
                     /locus_tag="ACIZE5_002745"
     CDS             3650..4258
                     /locus_tag="ACIZE5_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HGC6109832.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(4324..4497)
                     /locus_tag="ACIZE5_002746"
     CDS             complement(4324..4497)
                     /locus_tag="ACIZE5_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109833.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
BASE COUNT         1281 a          971 c         1232 g         1107 t
ORIGIN      
        1 tttgaccgac aggtataacc ctgccggtct ttttttgctg ctacaggaaa actacagact
       61 ggctacaggg aaagtacaga tgcgcttgcc ataataacaa tcgtaccagc cacaaatcgt
      121 agttttattg caaaggaggc attcgatcaa atggaaaaaa gcaactatca ttccaatgcg
      181 gatcatcaca aacggcatat gaaacaatcc gtggaaaagc gggcttttct atgtgcgttc
      241 attatttcgt tcacagtctg cacgctgttt ttggggtgga gactggcttc cgtattggag
      301 gcaacacaga taccgcccat ccctgcaact catacaggca gcagcactga cgtagtggag
      361 aatttggagg aaaacgctct tgccaccgcc aaagaacagg gagatgaaca ggaatggagc
      421 ctgattttag tgaacaggca gaaccccatc cccgcacagt acgatgtgga gcttgagcaa
      481 ctatcaaatg gtgagcggat agatattcgg atttctccct atcttcaaga tttgtttgat
      541 gccgcaagaa ctgatggagt ttacccgatt gtcgcatccg gataccgaac aacagaaaaa
      601 cagcaagaaa ttatggatga aaaaattgcc gaatataagg cgaaaggcta cacctctgca
      661 caggctaaag cggaagcaga aacttgggtg gccgtgccgg gaacgagcga gcatcagctt
      721 ggtcttgctg tggatatcaa tgcggacgga attcattcaa caggcaacga ggtttataga
      781 tggctggatg aaaacagcta tcgttttggt tttattcgtc gctacccacc agacaagaca
      841 gagataaccg gtgtgagcaa cgagccgtgg cattaccgat atgttggcat cgaagctgcc
      901 acagagatgt acaaccaagg ggtttgcctt gaggaatatt taaaaccaga aaaatgagaa
      961 aaggatgtta tgttatggac agaaaaagat tgacacagcg tttcccgttc ctgcttccaa
     1021 tgagacgggc gcagagaaaa atgtgctttt atgcgggaat gagatttgac ggctgtcgct
     1081 atgcgcagac gataggggaa accttttctt tctggtggct ggtacgccat gcggacaaag
     1141 atacccccta taaagacggc cttacggtga ccaatggtaa actcaccacc atgtcgggcg
     1201 gcggtatgtg ccagatgagc aatttactat tttggatgtt cctgcatacg ccattgacaa
     1261 ttatccagcg cagaggtcac gaagtaaagg agtttccaga gccaaacagt gacgagatta
     1321 aaggggtgga tgcaaccatt tcagagggct ggattgattt aaaagtgcga aacgataccg
     1381 actgcaccta ccaaatatgg gtgaccttag atgatgagaa aatcatcggt caggtgttcg
     1441 ccgacaaaga gccccaagca ttatacaaaa ttacaaatgg cagtatccag tatgtccgtg
     1501 aaagtggcgg gatttatgaa tatgcccagg ttaaacggat gcaagttgcc ttaggtaccg
     1561 gggaaataat agattgcaag ctgctttata caaacaaatg caaaatctgt tatcccctcc
     1621 cggaaagtgt ggatattcag gaggagaacc aatgagaaaa agtgtgggca ttactgtttt
     1681 tggatgcgaa caggatgagg caaatgcttt ccgcgcttta tcgccggatt ttcatattat
     1741 ccctacgctg attagcgatg cgatatcggc agacaacgca aaattggccg ctggcaatca
     1801 atgcgttagc gtaagccata agtccgaggt ttccgaggcg acaattcttg cgctgagaaa
     1861 ggtcggggta aaatacattt ctacccgcag catcggctgc gatcacattg atacgactgc
     1921 cgccgagaga atgggaatct cggttggcac ggttgcgtat tcgccggaca gcgttgcgga
     1981 ttatgctttg atgctgatgc tgatggccat acggggtgca aaacccacca tgcacgccgt
     2041 ggcgcaacaa gatttcagat tggatcgtat ccgggggaaa gaactggggg atatgactgt
     2101 gggagttatt ggaaccggcc atatcgggca agcggtcgtc aaaaggctgc ggggatttgg
     2161 atgccatgtg ctggcctatg ataacagccg aaaaatggat gcagattatg tccagcttga
     2221 tgagcttcta aaaaacagcg atattgttac gctccatgtg ccgctttgtg cggatacccg
     2281 ccatctgatc ggtcagaagc aaattggaga gatgaagcaa ggcgcatttt taatcaacac
     2341 cgggcgcgga gcgcttgtcg ataccggggc gctggtggag gcgttggaaa gcggaaagct
     2401 gggtggtgcg gcactggatg tgttggaggg cgaggatcag tttgtttata ccgattgctc
     2461 gcagaaagtg cttgaccatc cctttttgtc gcagctttta aggatgccga atgtgatcat
     2521 cacaccccat acggcgtact acactgagcg tgtgctgcag gatactacag aaaaaacaat
     2581 caggaattgt ctcaattttg aaaggagttt acagcatgaa tagaataaaa gtcgcaatca
     2641 tcttcggcgg ttgctcggag gaacatgatg tgtcggtaaa agccgcaata gaaattgctg
     2701 cgaacattga tacggaaaaa ttcgatccgc actacatcgg aattacaaaa aacggtgtat
     2761 ggaagctatg caagaagcca tgtacggaat gggaagccga cagtctcccc gccatactct
     2821 ccccggatag gaaaacgcat gggctgcttg tcatgaaaga aagcgaatac gaaacacggc
     2881 gtattgatgt ggctttcccg gttttgcatg gcaaatgcgg ggaggatggt gcgatacagg
     2941 ggctgtttgt attgtctggt atcccctatg tgggctgtga tattcaaagc tccgcagctt
     3001 gcatggacaa atcactggcc tacattctta caaaaaatgc gggcatcgcc gttcccgaat
     3061 ttcaaatgat tgataaaggt gacaagccgg aggcgggtgc gcttacctac cctgtctttg
     3121 tgaagccggc acggtcaggt tcgtcctttg gcgtaaccaa agtaaacggt acggaagaac
     3181 ttaacgctgc gatagaagcg gcaggacaat atgatggaaa aatcttaatt gagcaagcga
     3241 tttcgggctg tgaggtcggg tgtgcggtca tggggaacga ggatgatttg attgtcggcg
     3301 aagtggatca aatccggctg agccacggta tcttccgcat ccatcaggaa aacgagccgg
     3361 aaaaaggctc agaaaatgcg atgattacag ttcccgcaga cattccggtc gaggaacgaa
     3421 atcgggtgca ggaaacggca aagaaagtat atcgggtgct tggatgcaga gggcttgccc
     3481 gtgttgatct ttttttgcag gaggatggcg gcatcgttct aaatgaggtc aataccctgc
     3541 ccggttttac atcgtacagc cgctacccac gtatgatggc cgccgcagga atcacgcttc
     3601 ctgcactgat tgacagcctg attacattgg cgttaaagag gtgataagta tggaaaatgg
     3661 ttttttgttt ttagatgaaa tgttgcatgg cgtccgttgg gatgccaagt acgccacatg
     3721 ggataacttc acaggaaaac cggtggatgg gtatgaggtg aatcgcatca tcggcacaaa
     3781 ggccgtggcg tttgctctgc gcgaggcaca aatccatgcg gctgcgcttg gctatggctt
     3841 gcttttatgg gatggatatc ggccaagaac tgcggtggac tgcttcctgc gttgggcagc
     3901 gcaaccggag gacaatctca caaaagaaaa attttacccc aatatagagc gagccgagtt
     3961 gattacaaag ggttatgtgg cctcacaatc cagccatagc cgtggaagcg caattgatct
     4021 tacgctctac cacctggata caggggaact tgtttcaatg ggaagtaact tcgattttat
     4081 ggacgaacgg tcgcatcata cagcaaaagg gataggggat gcagaggcac aaaatcgaag
     4141 atgcttgcgt aaaatcatgg aaagcagcgg atttcagtct tatcgctttg aatggtggca
     4201 ctataagttg attgatgagc cataccccga tacctatttt aattttgccg tttcataatg
     4261 aaagtattgg ttttgtatca gattttggat ttgataaaat ctatgctggt catggacaat
     4321 cttttactgg aaagtggtta aagcatcttt tgtaatacat tgcaaattat agtattcaat
     4381 ctgcccagcg gcagaaaaga aaaaaaccgc tgttgggcag acctttccca cgcccatttt
     4441 gtattttgct ggcggcggtt ttgagaaatc aaggccgccg ttcttttctg gcagcaaaag
     4501 gtgtggcggc ccataggagg atgccgctat gctgttttgc tattgccatg ctctaatcca
     4561 cttccaccac tcaaaaaaag ccttgcccct c
//
LOCUS       DBBGSZ010000088         4430 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.094, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000088 DBBGSZ010000000
VERSION     DBBGSZ010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.094"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(543..2048)
                     /locus_tag="ACIZE5_002747"
     CDS             complement(543..2048)
                     /locus_tag="ACIZE5_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC6109834.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="ACIZE5_002748"
     CDS             complement(2045..2731)
                     /locus_tag="ACIZE5_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC6109835.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="ACIZE5_002749"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="ACIZE5_002749"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HGC6109836.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1238 a          919 c          729 g         1544 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat
//
LOCUS       DBBGSZ010000089         4416 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.096, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000089 DBBGSZ010000000
VERSION     DBBGSZ010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.096"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            59..913
                     /locus_tag="ACIZE5_002750"
     CDS             59..913
                     /locus_tag="ACIZE5_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGC6109837.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1010..3259
                     /locus_tag="ACIZE5_002751"
     CDS             1010..3259
                     /locus_tag="ACIZE5_002751"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGC6109838.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKIPEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3262..>4416
                     /locus_tag="ACIZE5_002752"
     CDS             3262..>4416
                     /locus_tag="ACIZE5_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6109839.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1556 a          626 c          806 g         1428 t
ORIGIN      
        1 gtaataatat aaacataata aaacaaaaat tatccaaatc taacatagga gggtggatat
       61 ggaaaattct atatatttag taacagaacc taacactcag ctgaaagatt gttactttaa
      121 tttttgtggg tattcaaaaa cagaacctag acatagtttt ggaccagcta ttcgagaaca
      181 atacttaata cacatagtgc tagaaggtga aggctattat tcaattaatg atcaaaaata
      241 ttttctgaag aaaggccaag gatttgttat cccaccagga gtatctactt tttatcaagc
      301 agatgaaaaa aatccgtggt catatgtatg gttgggttta agtggcaatc ttgtagaata
      361 ctatctaaaa gaaattggtg ttggaaagaa tcatcttacc tttaaagtcg aaaatttaaa
      421 ttcatttaaa ggattaattt ttgaaacttt atcgtatgat caggacaatc tagtcagtga
      481 attgtccaga caaaaacaag tttataaatt tttagaactc ctcttaaatt cagctagtta
      541 tctgaacgaa gggataatta ctaaaaagat gaatcctttt gttcgtcaaa caattgaaat
      601 aatacgtgag aatgcgtatc aaaaattatc tgttaaagat attgctgtca gtctatcgat
      661 acacgaaaat tatttatcac gattgtttaa gaatgatatg ggaatatcaa taaaagagta
      721 tattagtgaa atcaaaattt ctattgcaaa cgatctgtta tcatcaactg aatattcaat
      781 ccagcaaatc agtgacaaga taggattctc aacagtacaa tctttttcta aagcctttaa
      841 gaaagcaaat ggtgtttcac cgggagtata tcgaaaacgt agattaggtc taggaatcat
      901 taatggtgaa taaactaaac atttgatttt gataaatatt cgttacttta aacgcttact
      961 atttatgtga gcgtttttta taatgcaata aagaaacgga ggagagctta tgtataagga
     1021 taatgaaatg aatattattt atcgatcaga aaaccaacaa tttcatttgt ttaatcagga
     1081 gataagttac atttttaaga taccggaaga tggtaaatta ttgcatttat attatggtga
     1141 gaacttacca gataatgact atagtcatct aattgagatg catcatcggc ctatgacaac
     1201 ctatagaaat gaaaacgatt tgctatattc gttagagcac ttaaaacaag aatttcctga
     1261 atatggtaca acagatttta gacatcctgc tatttcatta ctacagaaaa atggctctcg
     1321 cttatcagat tttgtctatc aagggtacga agtggaagaa ggaaaaccta aactagaagg
     1381 tttacctgct acctatgttg ataataatga tgaaagcaaa acattgaaag tttatatttt
     1441 agattcagtt acaaatgttc aagtagaatt attatataca atttatagag attatcctgt
     1501 tattactcgt agcgcgcgag ttatgaataa aggaaaagat attcaaataa tcgagaatat
     1561 tagcagttta tcattggatt tacccgatgc aaattatgaa tggcaacaat tatctggtgc
     1621 ttggggtaga gaaagaacta ttaagtcgcg tactttacaa caaggaattc aatcaatcga
     1681 atctactcga ggtatttcaa gccatcagca taacccattt gttactttaa aaagaaaaaa
     1741 tactgatgaa aatcaaggag aagctattgg tgcagcacta gtttactcag gaaacttctt
     1801 aattcaagca gaagtagata catgggatgt tactagacta caagttggca tcaatccatt
     1861 tggatttaat tggaaactca atccaggaga aatatttaca gcaccagaag cgattctggt
     1921 ttattcaagt aagggtttaa atgccatgag tcaaactttt catcaactat ttagaaaacg
     1981 cttagctcgt ggtaagtggc gagaaaaaga ccgtcctgtc ttaattaata attgggaagc
     2041 aacatatttt gattttgacg aagaaaagtt ggtaaatatt gctaaaaaag catttgatgt
     2101 tggtattgaa ttatttgtat tagatgatgg ctggtttgga gaaagagaaa acgattgtgc
     2161 aggattagga gattggcatg taaatcctaa aagactacct agaggaatcg gcagcctttc
     2221 agaaaaaatt cgtagttttg gtatgaaatt tggtttatgg tttgaacctg aaatggtgaa
     2281 taaggatagt gagttatatc gcacacatcc gaattggatt atttctacac ctaatcgaaa
     2341 acctaatcat ggtaggaacc aatatgtatt aaattttggg ttagatgagg ttgttgaaaa
     2401 tattttcgat caaatgtgta aaatcattga tgaatcaaac ttagattaca ttaagtggga
     2461 tatgaatcgt ccattgactg atgtatttga cagtcacttg tcagcagatc aacaaggaga
     2521 agtattccac agatatgtac taggcgtata tcgcttatat gaaaaactta taacaaaata
     2581 tcctaacata ctatttgagt cttgttcatc aggtggtggg cgctttgatc ctggaatgct
     2641 tcactatgca cctcaagctt gggctagtga tgattcagat gcaattgaaa ggttaaaaat
     2701 tcaatatgga actagtatgc tgtatcctct ttcgtctatt ggtgctcatg tatcaattgt
     2761 tccaaatcat caaacaaacc gtataacacc tataaaaact agaggaaatg tagctttttt
     2821 tggtgcattt ggatatgagc ttgacttaaa tgaattaagt gaaggcgatt tgaggattgt
     2881 aaaagaacaa attgcctttt ataaaaaata tagaaccata attcataatg gtacttttta
     2941 tagactatta tcaccattcg atgatgataa tcaaaccgcg tggatggttg ttagtcatga
     3001 taagaaaacg gctattgttg ctcattataa aacattaaat gaggtaaatg ctccttaccg
     3061 ccgactgaaa ttaaaagggt tagataatga cggactttat aatgtaggac aaaatagttt
     3121 gcgatctgga atggaattga tgagagcagg actagtctgt tcagatgcat ctagtggaca
     3181 aataaatgat cagaatcgac gcccagaaac atttgatttt gattccaaga tttgggttat
     3241 aacacaggag gaaaagtaga gatgaataac caaaaaagct tacttcaaaa aggagcaatc
     3301 ttaagtattt cactaatgtt aacaagctct caagcaatta atggtgttat tccacaaatg
     3361 aaacagtctt tggggatatc acaaagtcaa agtgaacttt taggaactgc accaagtata
     3421 actgttattt tgtttatctt attatctagt tactttgcca aaagaatagg aatgaaaaag
     3481 acaataattt taggtttatt attagctggt ataggaggaa ttattccagt atttacagct
     3541 accttccaaa ccgttcttat tagtcgagta atattaggtg ccggtttagg agtatataat
     3601 tcattggctg tgacatatat cagctcttta tactctggca atactagagc aacgctatta
     3661 ggtattagaa attcaatgga agctttaggt cagacaatcc ttatttttct tgctggagtt
     3721 ttagtgaaca ttaattggac ggcttcgttt ttagtctatg caattgcgtt tcctgtagct
     3781 ctcttattcg cgctaaaagt tcctgaaatt agagatgaaa atagtgacat acctgaaaat
     3841 catgtaaaag aaaagatgaa tccaatggtt tttgccctag ttctatttgc aatcttactc
     3901 gtaatgaata gtattgctat ttctgtacga tttgcatcaa ttgcaactga aattaaaggg
     3961 gtaaacttta atgctagtaa ctatttagct ctaatgccta tcttaggaat actagcagga
     4021 tttatgtttg gaccaataaa taagtggata ggaaaaggaa ccctatactt gggaattata
     4081 ttctttataa tttcaaattt gttaattgct gtgtcaaacg gtaatatgac gttcctgcta
     4141 acgggtttat ttttatcaag tataacagga tcatggtgct tcccatttat ctttagtaac
     4201 ttagataaag tcactacaaa gaatacaatt aattttgcta cttcattgat ttttattggc
     4261 tgtaatattg gtaattttat agctcctatt gctatgcaat tagcacaatt tctaacaaga
     4321 agtacaaatt tgactgctcc attttttgta ttcgcaggaa tatttattgt gatcctattt
     4381 gtaacatttt ttgcgacaaa taaaaaaaat actaga
//
LOCUS       DBBGSZ010000090         4372 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.097, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000090 DBBGSZ010000000
VERSION     DBBGSZ010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4372
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.097"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(83..1051)
                     /locus_tag="ACIZE5_002753"
     CDS             complement(83..1051)
                     /locus_tag="ACIZE5_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGC6109840.1"
                     /translation="MSKKRTIVNEWEKLTALSNRRLNVQTLVQTIKLNWSIDRITIVG
                     KLNQNIFYHTQHDVLILDFEQLMRVNEGNGYLKAVGNNGWQLLDQHDENIAYIEISKW
                     QEGKGRIDFNPNKISRFLADSMKNFIHDLFLEPHFSRADVACDLIDVPDEFITQYRII
                     DPVSFKLIYGRSGKLETVYWGSRASERQIRLYNKKIEQEMKRKVVPSEINTWWRLEMQ
                     LRRGKATEWYAMVKESLDSFVSPHFLPTDIKPTDKVMIDGLLANHSNWAILSRNSKYK
                     YRNLLKRESQNDELTNHLRETFEESADDLKKELDTWLQGLDVTEEE"
     gene            complement(1496..2902)
                     /locus_tag="ACIZE5_002754"
     CDS             complement(1496..2902)
                     /locus_tag="ACIZE5_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HGC6109841.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDRQKTNDWHKHIDFTKSDEN
                     IYLEQTNLADKYEELFGEVVEKYNAKQKRADRKIEDYLAKVRKDKKLEPQREFIVQIG
                     ILDDFQTNRADGSSTGISKQQAEQNRVIANKILVQYYKEFQERNPNLAVYNAVIHNDE
                     ISPHLHLNIVPVAEGYKRGVQKQPSFNKALVQQGIHADKDNGRVLFNNFRNQEVDSIE
                     RLMNDYGWKRDIVGTNKIKDIHEYKEIMSEISELRQTAVKERESVSDELRYIYRQREE
                     NERDKALMASERAKIEEEKKNMLNVKKEMAVIFQKDMVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVATLEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQHKLERSENEIEW"
     gene            complement(3124..3486)
                     /locus_tag="ACIZE5_002755"
     CDS             complement(3124..3486)
                     /locus_tag="ACIZE5_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109842.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFETFADFERWLSSISDDQQHEKTVDNEWLADEKSAPSERDYPDESDDLFGVIPNKK
                     SQMSESKFTSIFNDVNLR"
     gene            complement(3490..3798)
                     /locus_tag="ACIZE5_002756"
     CDS             complement(3490..3798)
                     /locus_tag="ACIZE5_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109843.1"
                     /translation="MDKIDLREETVDRIELMYERLADYLNLPDEDNYSEMLERIMDVL
                     NSVINADLAKSSVLTNEFVHKHLAQTTDESEKEFWLKLMSHVMQLNQISVINSKEKEM
                     "
     gene            complement(3807..4226)
                     /locus_tag="ACIZE5_002757"
     CDS             complement(3807..4226)
                     /locus_tag="ACIZE5_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109844.1"
                     /translation="MTDLPEKMTIKNLADELGISKNTVRNQLVNAGYDLARYKDNGVI
                     MLDKELIGVVRSIYRSKGGQLTGDLPVNDAGNDFPLEKENEFLREQLAEKDRHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
BASE COUNT         1241 a          979 c          604 g         1548 t
ORIGIN      
        1 aaaaaaacaa cgacaacgtt atcacctgtt aaattcacca accaattttt cttaccaaaa
       61 tgcttttgtt tttctgccat tactattcct cctctgtcac atcaagtccc tgtaaccaag
      121 tatccaattc tttttttaaa tcatctgctg attcttcaaa tgtttctcgt aaatgattcg
      181 tcaactcatc attttgactt tctcgcttta ataaatttcg atatttatat ttcgagtttc
      241 ttgacaaaat cgcccaatta gaatgattag ctaacaatcc atcaatcata actttatccg
      301 taggttttat atcagttggt aaaaaatgtg gactcacaaa gctatccaaa ctttctttca
      361 ccatagcata ccattccgta gctttaccac gtcttaactg catttctaac cgccaccaag
      421 tattaatttc tgaaggcacc acctttcttt tcatttcttg ctctattttt ttattgtaca
      481 aacgaatttg ccgctcgctt gcccgactac cccaatacac cgtttccagt tttcctgagc
      541 gtccataaat taatttaaat gaaactggat caataattcg atattgcgtg ataaactcat
      601 caggcacatc aataagatcg caggcaacat ccgctcgtga aaaatggggc tctaaaaata
      661 aatcatgaat aaaatttttc atggaatccg ctaaaaatcg actgatttta ttaggattaa
      721 aatcaatccg cccttttcct tcttgccatt tagaaatttc aatataggca atattttcgt
      781 catgttggtc taatagctgc caaccattat ttccaaccgc ttttaaatag ccattgcctt
      841 catttacccg cataagctgt tcaaaatcta atattaatac atcatgttga gtatgataaa
      901 aaatattttg attcaacttt ccaacaatgg taattcggtc aatcgaccaa tttaatttta
      961 tagtttgtac caaagtttga acatttaacc gcctgttaga cagggctgtt aatttttccc
     1021 actcattcac gattgttctt tttttactca tattcagttc ctcctcaaag aaaaaagaga
     1081 tttttggaaa gaatttccag agttcacgta actctaaaaa ttcataacca tcaatctcta
     1141 gtcttgaaga aacctaaaaa tattcgtata atgaatttga gttacggaac tagtgtggtt
     1201 agtttccgta aaggtcgaga acgttggtag cgttgctcga cttatttttt tgctcttttt
     1261 ccagttcatt tgtttgctaa ctcaataata gcacttctct ttagctatgc aaataccaaa
     1321 aaaataaaac cgcacccttt gaaaagggcg cccccaaact tcgctaacgc taagttggcc
     1381 aaaaaatgga cttgccattt tttagcaaat gtcagcttca ggggctagtg gtttagccgt
     1441 caactcctta tcctcggcac aaaccgcctc cggtaccgtt gactgcacat cgtggctacc
     1501 actcaatctc attctcagaa cgctctaatt tatgctgtga gacgttttga cgataaaata
     1561 aggttttctc ctgctctaat acttctaatt cctcagaaag ccccatatcc ttttctgcaa
     1621 gaccaaaacg gatagacaaa cgagtgatcg atttttgaaa tgcgtttttt aatcgctcta
     1681 aacgctggcg taaagagcga ttttcttctt tcagcttttt attttccact tgtaaatctg
     1741 ctaattgttt tctaccagac aaatgacgct cttcttccaa tgtagctaca tactcattta
     1801 attctgtatt ttgctcaagc atctgtaaat attgctcact catgttatca gcatttctct
     1861 tggcatttgt tgctctcgta gctcgttgat acaaatcaac aaaatcattc ccagataaat
     1921 gatacgaacc atcaggaagc ctcttgaaac tttctaaagg aaccatatct ttttggaaaa
     1981 tgaccgccat ctcttttttt acattcagca tatttttctt ctcttcttca atcttcgctc
     2041 tctcagaagc catcagagcc ttatcacgct cgttttcttc tctttgccta taaatatacc
     2101 tcaactcatc agaaacgctc tcacgctctt ttacagccgt ttggcgcaat tcagaaattt
     2161 cactcatgat ttctttgtat tcgtgaatat ctttaatttt gttggtaccg acaatatccc
     2221 ttttccaacc gtaatcattc attaatcgtt ctatagagtc aacttcttga tttctaaaat
     2281 tattgaaaag cactcgacca ttatctttat cagcgtgtat cccttgttga accagtgctt
     2341 tattaaagct cggctgcttt tgaacacccc gtttataacc ttcagcaacc ggcacaatat
     2401 tcaagtgcag gtgcggactt atttcgtcat tatgaataac agcattataa acagccaaat
     2461 tagggtttct ctcttgaaac tccttgtaat actgaaccaa aattttattg gcaatcactc
     2521 gattttgttc agcttgttgt ttcgatatgc cagtagaaga accatctgct cgatttgtct
     2581 ggaaatcatc taaaatgcct atttgcacaa taaattctcg ttgaggttcc aactttttat
     2641 ccttgcgcac tttcgctaaa tagtcctcga tttttctatc ggctcttttt tgtttcgcat
     2701 tatatttttc taccacttcg ccaaacaatt cctcatattt atctgctaga ttcgtctgct
     2761 ctaaataaat attttcatcc gatttcgtga agtcaatgtg cttatgccaa tcattggttt
     2821 tctggcgatc agttaactca cgattattat gagaaatact tgtattcttc gttccttttt
     2881 taaatgaaat actaaacccc aagttaaaac cctccttcgc gctgtcgcta ataaaaagat
     2941 tgtaaacctt tctgttactc tttgtcaaag agtaacattt tcctaattgt gacatggatg
     3001 tcacaattcc aaacgctctc cgagggtttt cgctgtcaca agtgacaacg aaaaaaggag
     3061 ccgaaagcgt atcacgctat caactccttt tatgctttat tttgcttcac gcaaaataat
     3121 cgcttatcgt aaattcacgt cattaaatat tgacgtaaat ttactctcac tcatctgact
     3181 tttcttattc ggtatcactc cgaataagtc gtcagattca tcgggataat ctcgttcgct
     3241 tggcgctgat ttttcatcag caagccactc attatccact gttttttcgt gttgctgatc
     3301 gtcagaaatt gacgataacc accgctcaaa atcagcaaaa gtttcaaacc caaaacgctt
     3361 gcgaagagcc ttgcccattg cagcattttc tttctcaatc aagcgttttt tctgttggcg
     3421 aagtttcgct tgttcttttt ttaatttttc ttcttgcgct ttaatatctg ctaaagtcat
     3481 tcccataaac tacatctcct tttctttgga attaataacg gaaatttggt ttaactgcat
     3541 aacatgactc attaatttca accaaaattc tttttctgat tcatcagttg tttgcgctaa
     3601 atgcttatga acaaattcat tagtcaaaac tgaagatttt gctagatcag cattgataac
     3661 cgagttgaga acatccataa ttcgttcaag catttcacta taattatctt catccggcaa
     3721 attcaaataa tcagctaacc gttcatacat caattcaatt ctatcgactg tttcttctct
     3781 caaatcaatt ttatccatgt cacacctcac ttccagaatt gccaccattt tcgatttttt
     3841 aattcttgat tttctagtaa caactgatcg tttttttgtt gctgaagcaa agtcaatttt
     3901 tgttggtcac gaatcatttc cgttaattca gaaatatgcc tatctttttc cgctaattgt
     3961 tcacgcaaaa attcattttc tttttctaac gggaaatcat tgcctgcatc attgaccggt
     4021 aaatcaccag tcaattgacc accttttgac cgataaattg accgcacaac accaatcaat
     4081 tccttgtcta acatgataac cccattatct ttataccgag caaggtcata acctgcattg
     4141 accagttgat tgcgcactgt atttttagat atacccaact catcagcaag gttttttatg
     4201 gtcatttttt ctggcaaatc agtcattatc ttctccgtta ctttcagcta ccccataaac
     4261 atatttaaca gcatgcttag ggataatgat tggggaatca attttattat ttttcaaaat
     4321 caactcatac tgcgttacat caagtaactt accggacatt tttttgctat cc
//
LOCUS       DBBGSZ010000091         4116 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.098, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000091 DBBGSZ010000000
VERSION     DBBGSZ010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4116
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.098"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            155..316
                     /locus_tag="ACIZE5_002758"
     CDS             155..316
                     /locus_tag="ACIZE5_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HGC6109845.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            335..1612
                     /locus_tag="ACIZE5_002759"
     CDS             335..1612
                     /locus_tag="ACIZE5_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6109846.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1622..2278
                     /locus_tag="ACIZE5_002760"
     CDS             1622..2278
                     /locus_tag="ACIZE5_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6109847.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2278..3654
                     /locus_tag="ACIZE5_002761"
     CDS             2278..3654
                     /locus_tag="ACIZE5_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6109848.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3784..>4116
                     /locus_tag="ACIZE5_002762"
     CDS             3784..>4116
                     /locus_tag="ACIZE5_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HGC6109849.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT         1629 a          455 c          727 g         1305 t
ORIGIN      
        1 ctgcgcaagg cttaccagcg agatagagat cgacgatttg ttgtttgaat tcttttgaat
       61 aggttcttcg ttgacgtctt ggcatgaaaa atcctccagt gtgtttttta ttattctaca
      121 caccttattt tttctgtcta gtctagtgta gccgattcag gataaggata agtgtattaa
      181 ttgtggaaaa tgtaaaaaag tttgccaaat gaataaagat tcagttgaga attgcaatca
      241 tctggagtgt atcagatgtg gacgatgtaa aaatgcttgt ccagtggatg caattagtta
      301 tggagtaaga aaatagaaag gagtagttag gaaagtgata aaaaatgcta tagcatatat
      361 tacaagaaag aaaaatagaa ctttaataat ttttatcata ttaactatag ttctttcttg
      421 cttgtattct tgtttaacaa taatgaaatc aagcaatgaa atagaaaagg ctttatatga
      481 aagttctaat tcttcaatat caataacaaa aaaagatggt aaatatttta atgttaatca
      541 atttaaagat attgaaaaat taaaagaaat tgaagaaaaa ataattcaat atgatggatt
      601 agcaaaacta aaagatgcta aagtagttag cggagaacaa agaataaata gagaagattt
      661 atctgacgaa tttaagaatg ttgtttcact cgaagctaca aataatacta aaagaaatat
      721 tttatttagt agtggagtat ttacaattaa agaaggtaaa aatatagaag aaaatgataa
      781 gaattcaatt attgttcatg aagaatttgc taaacaaaac aatctaaaat taggtgatga
      841 agttgatctt gaattactag atattgaaaa aagtggaaaa ataaaaagtc ataaatttaa
      901 aattataggg atcttttctg gtaaaaaaca ggaaacatat acaggattat cttctgattt
      961 tagtgaaaat atggtgtttg tagattattc aacaagccaa gagatattaa acaattcaga
     1021 aaataatgaa attgcaaata aaattttaat gtattctggt agtgcagaat ctacagactt
     1081 agccttaaac aaattgaaag agcttaaaat tgatgagtca aagtattttg ttgaaaaaga
     1141 ttctaatgcg tttgaagagt ctttagagtc agtgagtgga ataaaatata taataaaagt
     1201 aatgacttat tctattatgt tgggtgggat ggttgttctt tcattaatct tgattctatg
     1261 gttaagggaa agaatttatg aaataggtat attcttatct attggaacat ctaagataca
     1321 aattataatg caatttatat tcgagttaat attcatatcg ataccaagta taatatcttc
     1381 cttattttta ggaaatgtat tactaaaagt aattgtagat ggattcatta actcagagga
     1441 ttcaatgatt tccggtggaa gtttaataaa taatagtagt tttatgtcaa atataacaac
     1501 acttggacaa agttatttaa tattaataag tattattgtt ttatcagttg tatttgcttc
     1561 ttcattaatg ttaatcaaga agcctaaaga aatcttatca aaaataagtt aggagaaaat
     1621 aatggatata ttagaaataa agaatgtagc atatagttat gcaaattcta aagaaaaagt
     1681 tttgtcagga gtaaatcaaa aatttgaact tgggaagttt tatgcgatag taggaaagtc
     1741 aggaacagga aaatctacac ttctttcctt acttgctgga cttgataaac ctcaaacagg
     1801 aaaaatattg tttaagaatg aagatataca aaataaagga tatagtaatc atagaaaaaa
     1861 taatatatct ttagtatttc aaaactataa tttaatagat tatttatcac caattgaaaa
     1921 tattagatta gtaaataaat cagcagatga aagtatcttg tttgaactag gtttagataa
     1981 aaaacaaata aaaagaaatg ttatgaaatt atctggtgga cagcaacaaa gagtagctat
     2041 tgctagagca ttggtatcag atgctccaat aatactagct gatgagccta ctggtaatct
     2101 agacagtgtt actgctggag aaataattaa tatattaaag acattagcta aagatagaaa
     2161 taaatgtgta atagttgtaa cacatagtaa ggaagtagca gattctgcgg atatcatttt
     2221 agaactaagt ggtaaaaagt tgaaaaaagt aaataaaatg aatttggagg ttgaataatg
     2281 ataaaaaatg catttgctta tgtaactaga aaaagtttaa aatcattaat tatcatatta
     2341 gttattttat ctatgtcaac tttaagtctc attagtttat ctattaaaga tgctacggac
     2401 agagcttcaa aagaaacatt tgctaatata acaaatagtt tttctatgga gataaataga
     2461 caagtaaatc caggaacacc tagaggtggg ggaaatgtaa aaggtgaaga tattaaaaag
     2521 atatctcaaa cagatagtat agactcctat gtaaaaagaa taaacagtgt tgcagattta
     2581 gttgattatg atattattga aactcaagag actcttgcga atcaatcacc tgaaagagca
     2641 aagaatttta aaagaacagt tatgttaact ggggttaacg actcaacaaa agaaacaaaa
     2701 tttgtatcag aagcatataa attagtagaa ggaaagcatt tagaaaatga agataaaaat
     2761 aaaatcttaa tgcataaaga tttagctgaa aaaaataacc ttaaagttgg agataagata
     2821 aaaataaaat ctaatttatt tgatgctgat aatgagaaag gtgcagatga aacagtagaa
     2881 gtagaaatta aaggtctatt cgatgggcat aatagcggtg gagtaagtgc agcacaagaa
     2941 ctatacgaaa atacattaat cactgatatt catacagctg ctaaagttta tggtaatacc
     3001 gaagatacag ctgtatacca agatgcaaca ttctttgtaa aaggtgataa gaatcttgat
     3061 agtgtaataa aagatcttgg gaaattagat ataaattgga gagaatataa tttgattaaa
     3121 agttcatcaa attaccctgc attacaacaa tctatatcag gtatttactc aatttcaaat
     3181 aaattatttt ttggctcatt aatatttgca ggagttgtag tttcattatt attattctta
     3241 tggatgaatg ctagaaagaa agaaatagca gtattactat cattaggtat atcaaaatta
     3301 gaaatttttg gtcaattcct aattgagatg gtatttatat caatccccgc attcgttggt
     3361 tcctatttct tagctcaata tacagctgac aagcttggga ataatatatt gaataaggtt
     3421 actggtgata tagctaaaca aatagctaaa caatctgcat ctagccaatt aggtggtggg
     3481 gcagaagctg aaggatttaa caagacatta tcaagtttag atatcaatgt attacctaaa
     3541 ttcatgattt atgtagttat atttatgagt ttagtacttc ttgtatcatt gattatttct
     3601 tcattcaata tattaagaag gaatccaaaa gaattattaa ttgacaataa ttaaaatttt
     3661 cggtgctttt tagcaccaaa aatgagagtg taatataaac cgtgtaagta accatcaatc
     3721 ctaggcgggt ggttgcttca cggtttttat ttttctaaaa taagatcaag aggtgattac
     3781 acgatggcta gaaagaaaag aaatcctgat gctgagaagt tagctgaatc cattttgaat
     3841 acttatcaac ccgaatctgt agaggatatg caagatgttt taaaagatgt gtttggtccc
     3901 ttatttgaaa aaatgcttca aggagaattg aataaccatt tagggtatga cgcccattct
     3961 aaagagccaa agaaacatga caatcgacga aacggttatg gcaataagac gcttaaaacg
     4021 agctttggta aagtaaacat tgatgttccc agagaccggg aggcttcttt tgaacctgag
     4081 ttgattccta atagaaaacg agatgtctcc gacatc
//
LOCUS       DBBGSZ010000092         3878 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.100, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000092 DBBGSZ010000000
VERSION     DBBGSZ010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3878
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.100"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(718..3867)
                     /locus_tag="ACIZE5_002763"
     CDS             complement(718..3867)
                     /locus_tag="ACIZE5_002763"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009035 - type I site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HGC6109850.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
BASE COUNT         1076 a          803 c          637 g         1362 t
ORIGIN      
        1 ggactaatac aggtagtcct cttttttgtt attttgatat tctaaatcat tttttattgg
       61 attattccct tgttcgatat agacccaaat tgatctatca ataattatca aactgagtca
      121 tatagagaca aaaatttcaa aaatgacctg ttaaatggtc atcgaatatc atttaaaatc
      181 aatacgacgg agtcagacac ggagtcaaaa caagcccgct gagagtaaaa aatatataca
      241 gtcccatagg taaagtgcca caggactgta tattttttta tttgagatta cctgaaatga
      301 ttccatttac tttttatctc attttttcct actagttagt atcaaatact ctcctatttt
      361 ctcaataaac tattttgggt tacatggtat ctgaaacagc taaaaccttg tcattacagc
      421 aaaaaatcac tttatctccg tttcatttca gatacatttc acttaagcgg attccaaaaa
      481 aacaaaagaa aaaggaaccc ctagttagcc tatgcttttt attggttcct ctcaaaacac
      541 ggtcatataa caacggggtg gggtaaatga atgaaaaagg tggaggaaac attattcaat
      601 agctgtctta aatacttcgt tataaaatgt gaacaaataa aagacatcta tccctatttt
      661 ctacacttcc actttactac catctttgaa tcgtacaatt ttcttaactc ttctcgttta
      721 cctcaattca ttttcaagtg gaatcagctc atcatctaac attttacgcc atgctcgctt
      781 catttcttgt gggtatttaa atggcttcgc ttctggatgg ttggctttat atccttcgta
      841 atccttactg ttgataattg ctttcatatt aggaattgga tcttcacctg gcatatattg
      901 cagattagaa gcatgtaatt ctttctcaga aacaaaccac tcattggaaa agacatgaat
      961 caaatcatca ctcgcttgtg taaaatagcg acgtttaatg acaaagatat cttcattact
     1021 atctaaagtc cccacatcaa acgcatttaa aatttgtcgg taaacttctt tgactccttc
     1081 tgttttattc aatttagcca aagctttttc aatttcttct cgtgcatctg aactattcgc
     1141 cgcataagtt cctagtaatt gatcaatata agtagaatca atatcataca acttcgtggt
     1201 attttcacta taaaattcga tcgtggaaaa atcttctccc tctttttctg gttcttcctc
     1261 tattaatgaa cccttcacgg tctcgtacac gccaatttgt tcttccaaaa gttgaatttg
     1321 attgttcaag gttgaagatt tcaccatgtc atcattgtaa tcgtcataag tcactaacga
     1381 ttcataagca cgattcaatt cttggaatgc tttgacgtac tcgatacgga tttcaagtgg
     1441 cgtatgttca tcaatggatt ccatggatga aacctctttt aacttaccat atgcttgctt
     1501 gaatcttttt ttggattcct gataacttgg ataaatcaaa cccgattctt cttttgcttc
     1561 tgaatacagt tttgtcgcat cctcgacatt cttctccatt gtggctggct ttcggaaagt
     1621 aacaattagt ccttttgttt tttctggata cgtacggttc gtacgtgaaa aagcttggat
     1681 caatcctgca tactctagat tacgatccac aaatagggtt tgaatcgtag gtgcgtcaaa
     1741 acctgtcaat agacgatcca ctacgatcac taaatcaatt tgtttcccaa attgtttgaa
     1801 ttccgctctt tttcgtgcca aacgattatt gatgtctccg ttataacgct caatgtctgc
     1861 taatgaccag gaagtatcat aatactgatt atattcctca ataatttttt gcatttcttc
     1921 ttgttggaca cttgaatctc ggctgttttc ttctaatgaa taggtaatag cgattcgtgg
     1981 aaaatcagga tcctccatcg ttcttccttc acgaatgggc tgattaggaa actcttttgt
     2041 taaccagtca ggttctttcg tcatttcttt gatcgctcga taatactttt tggccatgtc
     2101 aatggaactc gtggttaaga tcgcagactt cgttggacgg ccatttcgaa aatcaaattt
     2161 tgtataggca ttgtctggac ggaacatttt atgaatgact ttttggatat gttcatctgc
     2221 ttcaaaaaca gtagggtcca aataactttc ttttttgaca ggctccattt gatcaatcat
     2281 acgattgatc tgttccggtg aatactctgc atatgtttct acttctttta atttccgata
     2341 gattttattc tctaatgaag tcggctccac ggtgttttca tgctctactt gaaatcctaa
     2401 aaccgagcca tcttctaatg cattcttgat ggtataggta tgcaagacct ctccatactg
     2461 atcatgggtc gtacgtgcca attgcccttt ggcttgtttc cgattctcag ggaaaatcgg
     2521 tgtacctgta aagccaaacc aagtggattt cggaaacatt tttttgattt cttccatatt
     2581 ttcagcactt aacgctcgat gacactcatc tactacaaac acgatatgtt gccccattaa
     2641 tttttggaag cgattggttc cttttttctc ttcttgtttt tttgcatatt tcaacgccgc
     2701 atctagcttt tgacgggttg taataatcac aacatttgca ttggcatctg ccaacagagt
     2761 ttcacttaac tctttggcac ttcctgttcc cacgatcaag ctattcgctt tggcgttccc
     2821 ggaagaaatc ccagtattaa attccgaagc aaatttcgta aactctgtgg tggtttgatt
     2881 atctaaatct ttgcggtcca ctaacatgat cgtccgatcg atccccgatt ttcgtgctaa
     2941 aagcttagta gatacaaaac tagtcaacgt ttttcctgaa ccagtcgcat gccacacata
     3001 tcctgattga tgtttatttg cagcaataaa caaggcttga atcgcatgta cttgataagg
     3061 atgtaacacc atgaggattt tattgtcttg atcttcactg acaatcgtat aatccgcaat
     3121 caagcgatga gcatccggga tatttagcac ttgtttgcaa aactcatata agttttctac
     3181 ctttttatta tctttcgttc gccaactaaa taaaaactta ggatgcaaat cctttggtaa
     3241 ggcatttgca aaataccgag tggtttgttc attggaaacc acaaacaact gtaaggtcga
     3301 aaagatattg ttccgaaaca taccttcttc tgcatatttt ttgatttggt taaacgcctg
     3361 ataaaaacta tcttttgcgg ttacttgttt cagctcgatt tggacaatcg gtaatccatt
     3421 gatcagtaag gtgacgtcaa aacgtcgatc ccgtgcttct atgttacttc cacgttttgc
     3481 aatttgatgg accacttcat aggtagagat tcctccacca atgtcttgat tagaataaag
     3541 aatgagcgag acagaaccca gttgcggatc ttcccgttca atcgtgatcc gagccattcc
     3601 attttcacct tttaaccatt tcgcagcatc aaagggggtt ttcgttcgta gtaacaattc
     3661 tgttttgatc gtttcaaatt ctttatcggt caaaggaaaa tcattcagtt ctgcttgatt
     3721 atttgagatg attttttggc gtaaattgac ccaaagatct tcttctgatt ttagatcggg
     3781 acgatacgtc cactgattat gcccttcccc caatacacgg atcaactgtt cttcgacttc
     3841 cgcttcctca cggtgactaa ttttcattta tcttccct
//
LOCUS       DBBGSZ010000093         3844 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.101, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000093 DBBGSZ010000000
VERSION     DBBGSZ010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3844
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.101"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(38..289)
                     /locus_tag="ACIZE5_002764"
     CDS             complement(38..289)
                     /locus_tag="ACIZE5_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase family DNA-binding protein"
                     /protein_id="HGC6109851.1"
                     /translation="MEQLALVNLSALKASLAESEIANEVWDTKQAAEYLKTTTRTLTK
                     DAESGKIPAAKVGREWRFSSIALYQYLKGGKTWANSTEH"
     gene            complement(303..494)
                     /locus_tag="ACIZE5_002765"
     CDS             complement(303..494)
                     /locus_tag="ACIZE5_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109852.1"
                     /translation="MSNLDNGRAAIKKFMRENGVTMEDLATAYGYTRVRMQQIIDGHW
                     SGPKANKTILEIIRDYRIR"
     gene            787..1107
                     /locus_tag="ACIZE5_002766"
     CDS             787..1107
                     /locus_tag="ACIZE5_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6109853.1"
                     /translation="MTLFERIKSLASQRDKSMKEVALELGFSENLFYRWKTTEPKARD
                     LQKVADYFNVSVDYLLGREEKETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            1125..1547
                     /locus_tag="ACIZE5_002767"
     CDS             1125..1547
                     /locus_tag="ACIZE5_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGC6109854.1"
                     /translation="MYLKLKEMLSEYNLKLIYMEMEEPGFYYPKPRIVFLNEKLHEDS
                     SEAFHLAHELGHFIASHFEYSVLYDNSTTFHSKFEAEADRIAIMILLNIFIENELTDE
                     SQFKLENFMEFYSINNKLRTECFNVCQSYFKKKYSYAQ"
     gene            1630..2265
                     /locus_tag="ACIZE5_002768"
     CDS             1630..2265
                     /locus_tag="ACIZE5_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HGC6109855.1"
                     /translation="MAKKVMGQDGKMYKVKKPFYKRVWFWVLIVLLFFGIGGALSGGE
                     NKDSATATSTSTNKETTKETTTKEEKTYKIGDDVAVGKMEYKVNSVEVVKQVGPSVLP
                     TNAKDTFLVVDLSVKNAGDKAVTVDSSFFKLKADGKTFEADSAASMSANQDENGNITN
                     SFFMESLNPDMQQTGKIVFDISEAQANAQNNVLQAQTGYFGTETVSIALHN"
     gene            2383..3594
                     /locus_tag="ACIZE5_002769"
     CDS             2383..3594
                     /locus_tag="ACIZE5_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6109856.1"
                     /translation="MSEVTGYLEQVDNETYRLRAVLGYKPDGSAKRKSKTIKANSKRA
                     AYKELNIWLEQFEGMTDDSLDLFNITFGEFYRKIWLSEAEKNLEPKSYHNYKRMIENR
                     FLDKFDFIPLIDIKPYMIKKIVVNAQRINTKDPGRNSDKPLSRNTKLRMLYAVNNLFL
                     MAKNEYGAIKENPVENVKIPKEKGVKKNIEEPYSEEEIHAMLKAAFEESIEIKTLIVL
                     AFITGARQGEIAALEEKDIDFDKQEIRFHQRISEVDGKSDIRLLPGLKNDDDEKIVTG
                     PAYLFDMLDELIKENKKIRWKLNIKKLRHYFIFDTKQDGTLPRGSYLYKKFKRFTKRH
                     NLRHIRFHDIRHTSATYLLSDPNMTPKELQKRLGHRDFNTTMNVYGHVLRKEKDTATT
                     AFEKLLKKDIK"
BASE COUNT         1415 a          610 c          683 g         1136 t
ORIGIN      
        1 aggcctaaag cgtagatgat gaatggtgtg ctgaatacta gtgctctgtt gaatttgccc
       61 atgtttttcc tccttttaga tactgataca aagcgatact actaaacctc cactctctgc
      121 caactttcgc tgctggaatc tttccagatt cggcatcttt agttagcgtg cgtgtcgtgg
      181 ttttcaaata ttccgcagct tgctttgtat cccacacttc atttgcaatc tcagattctg
      241 ccaaagaagc tttgagggct gagaggttaa ctaaagctag ttgttccatt gattaattcc
      301 tcctatcgaa ttctgtaatc acggatgatt tctaagatag ttttattagc ttttggtcca
      361 ctccaatggc catcaataat ttgctgcatt cgaacacgtg tgtatccata tgcagtagcc
      421 aaatcttcca tagttactcc gttttctcgc ataaacttct tgattgcagc acggccgtta
      481 tctagatttg acatctattc actcccctta catatagatt tgtaagtcaa aatgatagaa
      541 aaaacgtata aactattgac taatagtata caatcgtata ctatataaac atagttaaat
      601 aagcctacaa caaacccttt attatgcaat cggtcgccaa acttaatgct ataaggtgta
      661 tttttagttt gctttttttc tatcaaatta acttacaaac aaataataat acaaacttat
      721 acttatgtca acagtataat ttacattttg tgtactttta tttgtttagg attggagaac
      781 attattatga cactgtttga aaggataaaa tcattagcta gccaaagaga taaaagcatg
      841 aaagaagtcg ctttagaatt aggatttagc gaaaatcttt tctatcgatg gaaaacaaca
      901 gaacccaaag caagagattt gcaaaaggta gctgactatt tcaatgtctc tgtagactat
      961 cttctaggta gagaagaaaa agaaacgcct aaacatgtgg atttatcaga agatgatact
     1021 gtattttctt ttgatggaaa agaaatatct aaggagacaa tgcgtaaagc gattgcaatt
     1081 gctaaagctt tagaggaaaa tgaatagttg gagtgatggg ttgtatgtat ttaaagttga
     1141 aagaaatgct gagtgagtat aatttaaagt taatctatat ggaaatggaa gaaccaggtt
     1201 tttattatcc aaaaccaaga atagtatttt tgaatgaaaa actacacgaa gacagttctg
     1261 aagcttttca tttagcccat gagctcggtc atttcattgc ttcacatttt gaatattcag
     1321 tactgtacga taactctaca acttttcatt caaaattcga agctgaagct gatagaatcg
     1381 caattatgat tttactaaat atctttattg agaacgaatt gactgatgaa tctcagttca
     1441 aattagaaaa tttcatggaa ttctactcta tcaataataa gttaagaaca gaatgtttta
     1501 atgtttgcca gtcatatttc aagaaaaaat actcttatgc acagtaaaaa aagcccgtgc
     1561 tgcaacacgg actcatacct catttctgag atcacaaata tattataaca agaagtgagg
     1621 gatatttaaa tggcaaaaaa agttatgggt caagatggga aaatgtataa ggttaaaaaa
     1681 ccgttttata aacgggtatg gttttgggta ttaatagtac ttttgttttt tggtattggt
     1741 ggtgctctaa gtggcggtga aaacaaagat tcagctactg caacatcaac aagtactaat
     1801 aaagaaacta caaaagaaac tacaacaaaa gaagaaaaga cttataaaat cggtgatgac
     1861 gttgctgtag ggaaaatgga atacaaagta aactccgttg aagtagtaaa acaagttggc
     1921 ccatctgtac ttcctactaa cgcaaaagac actttcttag tagttgactt atctgtaaaa
     1981 aatgcaggtg ataaggctgt gactgttgat agctcattct tcaaattaaa agcagatgga
     2041 aaaactttcg aagctgattc ggctgcatct atgtcggcaa atcaagatga aaatggtaat
     2101 atcactaact ctttctttat ggaaagctta aatcctgata tgcaacaaac tggtaaaata
     2161 gtttttgata tctctgaagc ccaagcaaat gcacaaaata atgtattgca agcacaaaca
     2221 ggttactttg gaacagagac agtttcaatt gctcttcata actaattagt ataaaaaaca
     2281 cgccccaccg accaaagcga gcgtgttcta agaaaaaaca aacctacaca ataggcttct
     2341 ttatagtacc tattgtatca gagaaagaga gctgattcaa ttatgtcaga agtaacagga
     2401 tacttagaac aagtagacaa tgaaacatat agactaagag ctgtattagg gtacaaacct
     2461 gatggctcgg caaaaagaaa aagcaaaact ataaaagcga atagtaaaag agcggcatat
     2521 aaagaattga acatctggtt agagcaattc gaaggaatga ccgatgattc gttggattta
     2581 ttcaatataa cttttggtga attttataga aaaatatggc tttcagaggc cgaaaaaaat
     2641 ttagagccaa agtcttatca taactataag cgaatgatcg agaatagatt tcttgataaa
     2701 tttgatttta tccctctaat cgatataaaa ccatacatga taaagaaaat tgttgttaat
     2761 gctcaaagaa tcaatacaaa agatcctgga agaaactctg ataaaccttt atcaagaaat
     2821 acaaagcttc gtatgttata cgccgttaac aacttatttt tgatggctaa aaatgagtac
     2881 ggagcaatta aagaaaatcc tgtggaaaat gtaaaaatac caaaagaaaa aggcgtaaaa
     2941 aagaatatcg aagaacctta ttcggaagaa gaaattcatg caatgctaaa agcagcattt
     3001 gaggaaagca tagaaattaa aactttaatt gttctagcat ttattacagg agcaagacaa
     3061 ggagaaattg cagctttaga agaaaaagat attgactttg acaaacaaga aataagattt
     3121 catcagcgga tttcagaagt ggatggaaaa tcagatattc ggttgctgcc aggtttgaaa
     3181 aatgatgatg atgaaaaaat agtaaccggt cctgcttatc tatttgatat gttagatgaa
     3241 ttgatcaaag agaataaaaa aattcgttgg aaattaaata taaagaaatt aagacactat
     3301 tttatatttg atacaaaaca agacggaact ttaccacgtg gaagttatct gtataagaag
     3361 ttcaaacgat tcaccaaacg tcacaatttg cgtcacattc gttttcacga cattagacat
     3421 acatcagcta cctatttgct tagcgatcct aatatgactc caaaagagct tcaaaaacga
     3481 ttaggacacc gagattttaa tactacaatg aatgtttatg gccatgtctt acgcaaagaa
     3541 aaagatacag caactacagc gtttgaaaaa ctattaaaaa aagatataaa ataacactaa
     3601 aaaattatat tttcgggtat aaactcgggt aggatatata aaaacttggg ataatttgcg
     3661 gtatataagc atttaaaaat gctgtaaatt cgcttatctt catttaaaat accattaaat
     3721 aacgaactct taatcagcgg gtcgcgggtt cgagcccctc acggcccatt gggtgccaaa
     3781 cccacggaac aggtaaatgt tggtgcgaaa gcatttcgaa aacatttacg ctgttctttt
     3841 ttta
//
LOCUS       DBBGSZ010000094         3421 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.102, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000094 DBBGSZ010000000
VERSION     DBBGSZ010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.102"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            648..965
                     /locus_tag="ACIZE5_002770"
     CDS             648..965
                     /locus_tag="ACIZE5_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HGC6109857.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(1056..1421)
                     /locus_tag="ACIZE5_002771"
     CDS             complement(1056..1421)
                     /locus_tag="ACIZE5_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109858.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1629..2111
                     /locus_tag="ACIZE5_002772"
     CDS             1629..2111
                     /locus_tag="ACIZE5_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109859.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2308..3198
                     /locus_tag="ACIZE5_002773"
     CDS             2308..3198
                     /locus_tag="ACIZE5_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HGC6109860.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT         1175 a          525 c          626 g         1095 t
ORIGIN      
        1 cttattgctt ttgcaaaatt tatttacctg ttttctggat caacgatagt gtacattatg
       61 ctatccttgt ttggatttta ggacgtttaa agaggcactt ttttacataa cttaatccat
      121 agacctttta agcatgctgt gagataataa taaagaagag tttaaagcgc accccaaacc
      181 acttccccat aagtgtatta cgctttaaac tcttttatat ttgaattcac taagaagcat
      241 accatatatt tgaatttact aagaagcata ccatattttt gaaaaaaagt gagaaaaaag
      301 gcttataatt aggatttaga gtaattaatt agatgtttat tttataggac tgatactata
      361 gattacaaat agtatcgtat ttcgcaatct taaaattatc ttcttactgt gaataagata
      421 ataaaatttg tatttgtcct ttttaggtaa cttattttaa tctatatacc tttctggatc
      481 aacgaaagta tactttatat agtcataacg ccgatggtaa ctatgcactg taacgataat
      541 gctgctaaaa tatcttttta cgaaaaacat cacaaggaaa aacttaacta tggtattatc
      601 taaacataat tttttcggta tttaatattt aattaggagg taatattttg cttttttata
      661 gtaattttat cttaatagta gcgatattat tacttctgaa tatatggatt tttgatagga
      721 gtagaaattc aagtataggt tttagaacta aacgaagttt gtcttctaaa aaaaattggg
      781 tatactcaca aactattttt tatggaggaa ttgttttaat tagtttactt tcttcaacac
      841 tttattcttt gaatattata gatgtttcca cctcaaattc aatatctatt attggaatca
      901 ttattgctgc aattattaca caactgtttt tagtgtttgg agagaagaaa agaagtaaaa
      961 aatagaaaaa ctagtgatag ttttggtgat ataagaaaaa catatatgta taaaaagaag
     1021 aaagtagctt ctctttgtac atatatggtt tgtttttatg gatgccgagc ttttttataa
     1081 gataaggcta ccgcccataa cgacccaagg atttgtggaa ctaagtaaat acctgcaaga
     1141 agcaagatca gctgggtcgg ttttaaagga tgatagaagt aacgccattc agtaaaattg
     1201 gcgcaaaata aataggaagt gacagtagat ataatattgg caatgaataa agatataata
     1261 cgcctgttcc tttgaaaata atatccagca aaaagagata aaaatatcaa tgtgatgaac
     1321 ccgcttacgg aatgataacg aaaatcaagc agtaaggcga aatgcacata aggaacaaaa
     1381 gataaaagca acggaaggtt tttccagcaa gtttttatca tctttcatca ccacctaaca
     1441 agtgttatta ttttgttagt tttattgtaa attgaatcct gcaataatca attacttttt
     1501 cattatttct agattaaatg aataaactct catgccatta tctctaaaaa aaaagttttt
     1561 ccccctaatt tttttagata gaaaattgta tagtatgatg agagaaaaag tagtttgggg
     1621 gaacgttaat gagaagaaaa gcagtaatcg atcggcttta tttatttttt tggttttttc
     1681 ctatcgtttt gctacctttt acatgggtaa atgctgttgt acaaggtgcg gagatattag
     1741 gcctgatcca aggaagcgga tttgtggttt ctaggaattt tccagctttg attgttttct
     1801 atttagtgat aagtgtaggt ctcttattac caaaatctct gatcaatcac tacaattggc
     1861 agctgcttta cttttcttgc ttattagtat ttacatctat gttttctttg ctgcctcgct
     1921 tgattatcgg ccctaatggt ttgagcgaga gtggattgaa ggatttagct tattcctcca
     1981 tgtatttctt gacgatcaaa ccatggttct atttagtaat tgcctcattt attcttgcaa
     2041 cattttttta cttctggaca gaaatcagga taaaaagtga acgatctgta tctataaaaa
     2101 ataactattg atggtggatc atcagtaaaa aaacatatga gctgcgtaaa atgcatgttt
     2161 ctcatatgct ttttttatta ttatgtaaag aatgcgaaaa acgtttacat gatttttaca
     2221 taacttaact atatttttac agcaaccata cgagggattt acagtcgact gataaacttt
     2281 agttgtaaat aagaaaggag caataaaatg aaaaaagtat tgtttactct aggtatgatg
     2341 ggaattcttt tagccggatg cggctcagga tcaggaaata cagatggctc tgccacacaa
     2401 aataattcaa gtgactcaaa tgaacaagta aaaatcgttg cggtaggttc gacagcatta
     2461 cagccgttag tcgatgcagc acaagaaagc tttgtacaag aaaatccaaa ttatcaaatc
     2521 tctgtacaag gaggaggaag cggaactggt ttgagccaag tcgaagctgg agcagttact
     2581 atcggaaact ctgatgtatt tgcagaagaa agagacggag ttgatgcttc aaaattagtg
     2641 gatcataaag tagcagtggt cgggatggca ccaatcgtca ataaagatac agatgtcaaa
     2701 gatatcacca aacaggaatt gattgatatc tttacaggaa aaatcactaa ctggaaggaa
     2761 gttggcggga aagatcaaaa aatcaacgtc gtgaaccgtg caaacggcag cggtacccgc
     2821 gcgacattcg aaaaatgggg actggatggt gctacccctg tgcagtccca agaacaagat
     2881 tcatcaggaa cagttcggca gctggtaagt caaacaccag gagcaatcag ctatttagct
     2941 ttctcatatc tcgatgattc cacacaagca ctaagtatcg acggtgtaga accaaaagaa
     3001 gagaatgtag cagataacag ctggggaatc tggtcatatg aacatatgta cacgaacgga
     3061 aaaccttccc ctgaagtcca aaaattctta gactacatga tgacagaaga aatccaagaa
     3121 ggacctgtca aagaattggg ctatttacca atcacaatga tggaagtaga acgtgatcac
     3181 gaaggaaata tcaaataact agcagataaa catgccacgg tagtcgttac tattaaggaa
     3241 aaatcaacta tgtttcccca catatacatt tttcctttaa ttgtgaaaaa tagttcctca
     3301 tattttgccg ttttttgagc taataccgag ggtcagctga ttgaacaccg tttattcgaa
     3361 aaaaagagct acgacataga actgtcgtaa ctttttttgg ctcttcgtca aatcgtgttg
     3421 g
//
LOCUS       DBBGSZ010000095         3282 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.103, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000095 DBBGSZ010000000
VERSION     DBBGSZ010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.103"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            2..586
                     /locus_tag="ACIZE5_002774"
     CDS             2..586
                     /locus_tag="ACIZE5_002774"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGC6109861.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(663..1838)
                     /locus_tag="ACIZE5_002775"
     CDS             complement(663..1838)
                     /locus_tag="ACIZE5_002775"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HGC6109862.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            1920..2300
                     /locus_tag="ACIZE5_002776"
     CDS             1920..2300
                     /locus_tag="ACIZE5_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvfD/Ygs/GSP13 family RNA-binding
                     post-transcriptional regulator"
                     /protein_id="HGC6109863.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            2374..2736
                     /locus_tag="ACIZE5_002777"
     CDS             2374..2736
                     /locus_tag="ACIZE5_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109864.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         1114 a          538 c          622 g         1008 t
ORIGIN      
        1 tatggcattc ccacaactag atttaaaaag tgaaaaagga ccaaaagctg ttatcaaaac
       61 aaaccgtggt gacattactg ttcaattatt ccctgaacta gcaccgaaga cggttcaaaa
      121 tttcattgaa ctttccaaaa aaggttatta tgatggcgtg atttttcacc gcgttattcc
      181 tgatttcatg atccaaggcg gcgatccaac tggaacagga atgggtggcg aaagtattta
      241 tggcgaaagt tttgaagatg aattcagtcg tgaactgttc aaccttcgcg gagctttatc
      301 tatggcaaat tcaggtccaa acacaaacgg aagccaattc tttattgtaa ataacacaaa
      361 tgtgccagct aatatgcttg gacaactaga aggtgctgga ttcccatcag aaatcattga
      421 agcgtataaa ggtggcggaa ctccttggct agatttccga catacagtct ttggacatgt
      481 actagaaggg atggacacag tagatgaaat cgcaaatgta caacgtggtc cacaagaccg
      541 acctgtacat gatgtagtga ttgaaacaat tgaaatttca gaatagtttg gtatggtacg
      601 gagtaattat gaaaaaggac gaaacctagt aaggtctcgt ccttttattt tgaataaatg
      661 atttaatcga ttgtctctaa agcatacttg attcgattaa gtccttccag taaagtttct
      721 tctggacaag caatattcaa gcgcatatgc ccatgaccgg aaggaccaaa cgtgatgcca
      781 ggatttaata cgacttttcc tttccgaaca agagtgttct ccaattcttg gtcgtctgaa
      841 atataggcgg taaaatctaa ccacattaag taagttcctt cagggttcat tattctcact
      901 ttcggaagat actgttcaaa aaactgatta actgtttgaa catttttttc tagataagga
      961 atcagttggc ttaaccattc tccacccgtc tcataagccg cttgggttcc aatcagtcca
     1021 aaagtgttga tttcgtgctg ttggttcatc actaaatgtt tttcaaaatc agctttcatc
     1081 tctggatttt tgataaatac cattgaattt ttgattgcag ctagattgaa agtcttggtt
     1141 gcggaagtaa aagcaactag tagatcatct aaattaggat caatcgttag catggaagta
     1201 aatgtatgat cgaataaagt taaatcttga tggatctcgt cactaaacag aatcacttga
     1261 tgttttaaac acaattcgct taactgtttc aattcttctt tgctccaaac acgccctcca
     1321 ggattgtgag gattgcataa aatcattgct tttacattgt tttcttcgat ttttttctcc
     1381 atgtcagaca agtccatgat gaaatgatta tttttttcta gcaaagagct tcgaacgatg
     1441 tgacgttgat ttgtttctat aatagaggaa aatggaggat aaactgggtc atgaatcaaa
     1501 atagaatcgc ctggttttgt aaaagtttgt actgctgcag ctaaactggt taacacacca
     1561 cttgtaaaaa cgatattttc tttcgtcaac tccacagcat ggtgttggcg ttcccaatga
     1621 atgatagcct gatatagttt atcagacaga gtggcataac caaagattcc atgtttgatg
     1681 tattcactaa acgctttagc taccccaccg ggagacaaga agtccatatc tgctacccac
     1741 aaaggaagta agtcatccat ttgatatgtc tcagcaattg cgtcccattt tacactttct
     1801 gtatcttttc ttgaaatctg tttatcaaat tcgatcatct taagacctcc agtcattttc
     1861 gtcgcttctt tttttgagct atttacagta taatgataaa tgcgaagaga gggaagtaga
     1921 tgacttataa aattggacaa ataattgaag gaaaagtgac agggatacag ccttatggcg
     1981 cattcgtttc tcttgataac gagacgcaag gacttattca tgtttcagaa gtacaatccg
     2041 gttatacgaa aaatatccat tcattgttaa aagtcggaca gccagtaaca gttcagatca
     2101 tcgacattga tgaatattcc aaaaaaatca gtttatcttt aagaacgtta gaaaaaacaa
     2161 atccagctgt tccatatcgc agaaaaaggt atttcacgaa taaaaatcgt aagatcggat
     2221 ttaccactat tgcggagcag ttacctattt ggatagaaga agcattatct gaactagaac
     2281 ggaaagaaaa taagaaataa aaagtgtatt ttttctgaaa atgtgctaga atttttatgt
     2341 aagccataga acaagttgat cgaggtggaa attttggcaa gcaaaagagt tgctggtaca
     2401 attatgttgc atttggagga tggtactaaa aaatttttgg tccattcaat tgatgacaag
     2461 ttggaatttg cgttagcgga actttctgaa ggaaagactg gtttagcgaa tatacttaat
     2521 ttcttaaaag aaatagttca tatcgatgtt agcaagatta gtttgatgga attgacaaat
     2581 acacatatta aagaggaaaa tgttccgttg tttgtctttg aaactgaaca aaagaatcaa
     2641 agagaagaat taggcgaagg atatatttgg gaagaaccag gtcaaatgcg ctctgttctt
     2701 ggaacttacg aagtagaggg agtgcctttc ttctaaaata cagattaagc gaacaaagaa
     2761 gtttgaattt ttttcaaact tcttttttta ttgtttggtc caaaaaatac aatgaaatgt
     2821 tctgctaaag atagtttttt agtgcatttt attttcaaaa tatgttgaaa acggttgtat
     2881 aacgaataat aataattgat cgaaaaatca tttcacaaag taatgcttaa tttatagttg
     2941 accaaggaag aaatacatga taaatttaac agcgttgatt ctgaagtgga tgttatatca
     3001 catttctaaa aaatttaaaa aatagttatt gacatgttac taacgacatg ataagataac
     3061 tgagtcgtta aaaaagaacc acttgcgaag cttgattcta tcgaaaaaaa cttcaaaaaa
     3121 gttcttgaca aataacaaac gataagttat gataaatgag ttgctgaaag atttcgaaaa
     3181 acgaaatcga aaaaaacttt taaaaaagag ttgacaatcg cttgtctctc tgatatgata
     3241 taaaagttgc tacggcagcc aaaaacgaat cgggaaacac tc
//
LOCUS       DBBGSZ010000096         3199 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.104, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000096 DBBGSZ010000000
VERSION     DBBGSZ010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3199
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.104"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            301..585
                     /locus_tag="ACIZE5_002778"
     CDS             301..585
                     /locus_tag="ACIZE5_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109865.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            588..1004
                     /locus_tag="ACIZE5_002779"
     CDS             588..1004
                     /locus_tag="ACIZE5_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109866.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(1141..1860)
                     /locus_tag="ACIZE5_002780"
     CDS             complement(1141..1860)
                     /locus_tag="ACIZE5_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HGC6109867.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFRSLMDIPEYYQMGNIDQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLE
                     FTFSSLTSDLPKISLRNWLEE"
     gene            2522..2608
                     /locus_tag="ACIZE5_002781"
     CDS             2522..2608
                     /locus_tag="ACIZE5_002781"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGC6109868.1"
                     /translation="MFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(2910..>3199)
                     /locus_tag="ACIZE5_002782"
     CDS             complement(2910..>3199)
                     /locus_tag="ACIZE5_002782"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109869.1"
                     /translation="EYRRQRSDFISRKIVRLEKEKMEKFPYEYFQNLEKLEQAIQAIK
                     FDLTDEKLLEYKNMTPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
BASE COUNT         1065 a          597 c          499 g         1038 t
ORIGIN      
        1 aaaaaaaatg tcgtttgaaa aactaaataa atttttgatc gtgcattttt aaatttggtt
       61 atcgattaca cgtgcagcac tcccccccga attttaaaga gcataaggaa acgtgtaccc
      121 actttctaaa aaaagtgggt agataggctg tgcctatcac gtttctcaga aaaaaatttg
      181 atatcacttt ttcgccatcg tgggtagctt atgtatagca ttttggcaaa aaacagctat
      241 acaaatatag tatttgtatg gtatacataa attatacata attgcaaaag gagatttttt
      301 atggacattt tagttcggaa tattgatcca aagtttgttg caacaataga caaacgttgc
      361 caagaactca cgaataaaac aggagaaaaa tggagtcgaa ataaatatct aaaagtttta
      421 atcgaaagtg attttgaccg tcaacttacg acttacaaaa aagaccaatt cgatttattg
      481 ctcgataaat ttattgctat ccaaacagaa aatactcaaa tattaagcga gtatgtctac
      541 acaaataatc aaatcattga aatgcttatc ggaggaatga tataaccatg agaaaaactt
      601 ctgtccaaaa acatgttact ttgtacccta gtcatgttga cgttttagat tccatcatcg
      661 aaaaaaatcc agatatcaat aactactcgg aagccattcg ctttttatgt atgagttatg
      721 aacccgatac caacacgacc actaccagca atcaggcaaa actaaatgct atgggaaaag
      781 aaatttccat catgactgaa atcatcgcag aatttgctga tttatatcta aaagatacag
      841 gcgttcttat tggcacaaat tctaaagtat atcaagaagt gaaagaaaaa atcgaagcta
      901 aactaaatcc atcaaatcga aatcgaccaa agaatcatca aaaagaaacc agtcaaacag
      961 tcacttctag aaatttcgac ccaacaaatt ttctaaaacg ataaaaaaca gataggagtt
     1021 attcctatct gttttttatt tagaagcccc atacaatatg ctagaatgta ctagcaatct
     1081 tagtcggttg taagggactt gtctacttgc ttaatgtaag gggggcgagt tcttttttat
     1141 ttattcttct aaccagttac gcagagaaat ctttggcaaa tctgacgtta ggcttgaaaa
     1201 agtaaattct aatttggcga ttttattgcc cttttttgct tttatttttg tgactttaag
     1261 atcattgaag tattttttta gttctcgtaa tgcaggattt aatacttttt gatcaatgtt
     1321 acccatttga tagtattctg ggatatccat taagctccta aactcttcaa tacgaactac
     1381 ataataacca gtagaacggt actgcataag cagtcggaat agagtttttg catacgtaga
     1441 acgcaacgac gtgaaagcag ataattcaaa tctactaaat tcagctgtta aaccattaat
     1501 aatatattct aggtccggat taacactgac ttcaacaaac ttttttgttt tattgatttc
     1561 aaaaccagta aacaaaacaa agtagcgaat agaatcctca tcttcagtac ggtaagtaag
     1621 attaagcata tctttataga gcttttctaa atcaccgaca aaggcttttg tagcagtcat
     1681 cttataatca cttaactctt ttaattcctc gaaagaaaat ctaacttttt tcaaaccacg
     1741 atctttcata cgagcgcata atgcaaaaaa taaatccatc tgcttagcat tgaaattttt
     1801 cagcggtact aaattcaatt cattttgata tttgactgtt aattccgttt tttcatccat
     1861 tcctttcttc cccccttaca aataaataat aacctttaac aaccaactcg taaataggtt
     1921 ggttgttatt atacaaaagg atattagtac tcagataaaa agttgttagt actcagataa
     1981 aaagttgtta gtactcagat aaaaagttgt tagtactcag ataaaaagtt gttagtaccc
     2041 ttctgtatcc gttgggagag taaggctcaa ctgcccccta aaaagggttc taaaaaatct
     2101 ttaaaaaata aataaaataa acgcgcgcgc gcgagcaaaa tttcccgcca aaaaatcacc
     2161 cactttttaa aataaacagg ttcgcgcatg atattaaact gccaatctag ctccctatgg
     2221 tcgctgtaag aaggagtgat cgctacgctc tcacatttta cttgcagcag tcgcctttag
     2281 gctccttcgc caaaaataat tcattaggga ctcctttgtg gcgtcctgag agctcgtcta
     2341 agccgttcta agacaagatt cgataaaaac tatgtccttc gttctaaagc gccttacagg
     2401 cggtcagggc aagccctaac aaccccaagg caataaaaaa cttaggctta tttttgcttt
     2461 tttattgtat aattgattgt cgcctatccg acagtcttgc gactggaagg aggtgtgttt
     2521 cgtgttcact aactttattt gctcccttct tgttgggctt ttaagcgctt tgttcagtta
     2581 ctggttgaat aaccgaaaca agaagtaaaa cttaattaag gcgactcagc ccacaaaaaa
     2641 agccccagag aatccgacct ctctggggct ttcgtgtgtt tcgtgttcac ttatttgcaa
     2701 tcaaattata acagaaataa atatttattt caaaaatatc ctacaaaagt ctaaaatccg
     2761 taattatttc ttatatgcaa catttacaaa taaagtcgct ctgagagctc gtatttttcg
     2821 atttaagacg ttttatttag tttttggtgt atttcattgg tccaagctaa aaaactctta
     2881 gaagcgattt tagagccatt taaacccact taattatatt ctccatgaaa ttcgctccat
     2941 gcgtcaaaag ctgcgtctga aattccgccg tcttcgttca ctagttgcat taatttttcc
     3001 aacgatcgtt ttctttcggg tgtcatattt ttatattcca acaatttttc gtctgttaaa
     3061 tcgaacttga ttgcttgaat tgcttgctct aatttttcta agttttgaaa atattcgtaa
     3121 ggaaattttt ccattttttc tttctccagt ctcacaattt ttctagaaat aaaatcactt
     3181 ctttgccgtc tatactctc
//
LOCUS       DBBGSZ010000097         3031 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.105, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000097 DBBGSZ010000000
VERSION     DBBGSZ010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3031
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.105"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            581..1540
                     /locus_tag="ACIZE5_002783"
     CDS             581..1540
                     /locus_tag="ACIZE5_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC6109870.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYRF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPLEVFLSYVGKDDLSSLI"
     gene            complement(1527..2132)
                     /locus_tag="ACIZE5_002784"
     CDS             complement(1527..2132)
                     /locus_tag="ACIZE5_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109871.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     LIYKIIEDDKQTELNMCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNS
                     LDFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKVSFVKLS"
     gene            complement(2372..>3031)
                     /locus_tag="ACIZE5_002785"
     CDS             complement(2372..>3031)
                     /locus_tag="ACIZE5_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HGC6109872.1"
                     /translation="YISLLCKEEVRELPKSNSAVGIDLGIIDFAILSTGQKFDNNKFT
                     SKMEKKLKREQRKLSRRALLAKQKGINLFEARNYQTQKRKVARLHEKVMNQRTDFLNK
                     LSTEIIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSSFVSKLQYKADWYGRKIIKV
                     DKWFPSSQICSNCGHKDGKKSLEIRKWTCPICHTHHDRDINASINILTEGLRLHSMGL
                     A"
BASE COUNT          988 a          503 c          471 g         1069 t
ORIGIN      
        1 aacaataaat gaagactttt ttattgttaa ttgtttattt ttctattatt agatatgaaa
       61 atcgcattta gataaaatag aaaaatatga atatatttta aatattaaga tgagagtcat
      121 taacttatga tagtagtcaa tttgcttttc actaattaca aaatatgtga tataggaagt
      181 ttagttattg ttctcataat gccatcctgt ttttagatta tctagtaatt tttttgttat
      241 ttaaaattag gagcagtgcc aattgtttta attttaaagg ctttttttat atcttctaaa
      301 ttagaagata tttgtatatc aatatggaat atattacctt ttttgtattt ttttatgtta
      361 tctttagcta aaacatcaaa tacatgtcct tgaaattgta tcgaggcagc tggatttagt
      421 ttaaattgag gaaactttac cacagctgat tcaaaacact tgtcacattt ttttattttt
      481 ttaccttcgc cgattgtaaa attaagctag acaactaaaa aagtcatttg tgctacactc
      541 aaaatagttc cgtcgaaaga attataagga gtgagtacaa atgacctata cccatcttac
      601 accaactgaa ctcgtaatga tagaagctta tttcaatcaa tcacactctg tttcaaaagt
      661 agcccatctg gtacaacgtt ctcgacaaac catttataat gtctatcgtt ttcttaaatc
      721 tggtggaagc gcaataagct actatgaaca atataagaaa aacaaacgta actgcggaag
      781 acgtccgatt gtgttaccag atgggcaaca agaatacatt caaaaaaagg tggctcaagg
      841 gtggactcca gatgtcctta ttggtcgagc agagtttcct attgcttgtt cggtacgtac
      901 actatatcgg atgtttaaag ataaaacctt tgatcctcac gatttaccaa tgaaagggaa
      961 aagaaaacca aacggacata aagaaaaaag aggaaaacaa gcttttcgcc gttcgattca
     1021 ggatagaaca actgattata tacagttcaa tcatgagttt ggtcacctag aaggtgacac
     1081 cattgtcggt ggaaaacata aaagtgcggt gatcacgtta gttgagcgat tatctaaagt
     1141 gatcatcacc ttgaaacccg ctggtaggca agctatagat attgagaata gactgaatca
     1201 atggtttcaa tctgtaccga aacacttgtt taaatccatc acatttgatt gtggaaaaga
     1261 gttctcgaat tggaaaaaga ttagtaatac caatgatatt tcgatttatt tcgctgatcc
     1321 aggaacacct tctcaacgag gactaaatga acattcgaat ggcttattac gtaaagatgg
     1381 cttatataaa gctatggatt ttaataaggt atccgaaacc tttatccaat cggtggcatc
     1441 aaaacgaaat catattccta gaaaatcatt acactatcgc acaccattgg aagtattttt
     1501 gagttacgta ggtaaagatg atttgtctag cttaatttga caaacgaaac tttgtaaaaa
     1561 tattcgattg aatattctat ttggcacgac tcacttggca gtatatgtat gtcaatattt
     1621 ttcatctgtt tcataggtat ttcaaaatct aaactattaa aaacatataa ttccctgtaa
     1681 ttatttacat ctaactctac taaatttatc tttggaacaa tagatcctcc acccattcca
     1741 ccataataaa aaaaatcttg ttctctatca aaatagcaca tattaagctc agtttgttta
     1801 tcatcctcaa taattttata aatcaaacct atataatcat gaatgctggc aaaaattttt
     1861 tttaagtcaa gttctaaatc ttcttcgaaa acacatttaa tttctcctac tgataattga
     1921 tactctatat tacatgactt aattagtttt ttagatcccc cctccagata ggcatatgtt
     1981 tcaataatta tgttcttttt attgcttggc aaatttccgt tatttattgc ataaattaaa
     2041 aatgactgtc tatttagccc ataatctaat acaacttctt catactcata tttctttaaa
     2101 tatttaatat gaaaatatgc tgaattaatc aaaactcgag tgttactgtt gttatttatt
     2161 gttgttctat tgtgtataaa attgtatagg ttgtcatatt ttcttggttt agtgaactac
     2221 tcaccactta gctaaaccta acggtttctt acgtttgaag tgggagcttc ttgggaagag
     2281 agcatacttg atagcgtatt actttactaa cagaggtgcc tcttatttac caagctatcc
     2341 ccgtagttcc tacggttctt gtttatttga tctaagccaa tcccatagag tgtagcctta
     2401 gaccttcggt caggatattg atactagcgt tgatatctcg gtcatgatga gtatgacaaa
     2461 tagggcaagt ccattttcga atttcgagag atttcttgcc gtctttatgt ccacaattcg
     2521 aacagatttg gctagatgga aaccacttat ctactttgat gattttccga ccgtaccagt
     2581 cagccttgta ttgtaattta gacacaaaac tagaccaaga aacatccgaa atactttttg
     2641 ctagtttatg attacgcaac atgccttttg tgtttaagtc ttcaatacag atgatatcgt
     2701 gatttttgat aatttctgta ctcaacttat tcagaaaatc agtacgttga ttcattactt
     2761 tttcatgcaa tcgtgctact ttacgttttt gtgtttgata atttctagct tcaaacagat
     2821 tgataccttt ttgtttagct aataaggcac gtcttgacaa cttacgttgt tcacgtttga
     2881 gtttcttttc cattttggac gtaaatttat tattatcaaa tttttgaccg gtagaaagaa
     2941 ttgcaaagtc tataatacct aggtcaatac caacagcaga attagattta ggtagttcgc
     3001 gaacttcttc tttgcataac aaagaaatat a
//
LOCUS       DBBGSZ010000098         2698 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.106, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000098 DBBGSZ010000000
VERSION     DBBGSZ010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2698
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.106"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(139..609)
                     /locus_tag="ACIZE5_002786"
     CDS             complement(139..609)
                     /locus_tag="ACIZE5_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109873.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            696..1394
                     /locus_tag="ACIZE5_002787"
     CDS             696..1394
                     /locus_tag="ACIZE5_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HGC6109874.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            1572..1913
                     /locus_tag="ACIZE5_002788"
     CDS             1572..1913
                     /locus_tag="ACIZE5_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109875.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            1906..2577
                     /locus_tag="ACIZE5_002789"
     CDS             1906..2577
                     /locus_tag="ACIZE5_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HGC6109876.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
BASE COUNT          995 a          391 c          545 g          767 t
ORIGIN      
        1 ataggaacga ttgtttacat ggtttggatt tttatggggc ttgatgaagc tgaagctgag
       61 tacagagcga aaaagccaac cgagggggct gactaaaaat gaatagaaaa gagaaactag
      121 aatgtatatt actattactc agtttaattc tttcactaat ttctctattg ggaagtttgt
      181 atttttgata tcaacaattt tgtggatttg ggttctattt agagtaaata tcatttttgt
      241 ttggtgatta aggagtttat taaaattaat tttccctact tcaaatgcaa ggtaacaaga
      301 tatagcactt ttaggaggaa tatttagcgg tacagcttca gagtatattc tattatcatc
      361 gactgatcct cctttagcaa ttaatttctt aaatggagta gctgaccatc tgcggtttaa
      421 gttagcggat gaaagttcta aattaactaa catagctggt tctgttgaat agttagaaat
      481 gattactttt gtataaatca tatctgcagc gaagtaagaa gcattaagtt caacttctag
      541 ttgagggcgc attcctttta tttttatccc tgttaaaaac gtactcaata taaaacttat
      601 tattgacatc cattgaaaaa ttgttaagtg aaaaaaattc aaaataaaca ccaccagttt
      661 ttaactaaat tataccaaaa aggagagaag aaataatgca agaattagta attttgaaaa
      721 ataaagaagc tgtgactacg agcttacaag tggcagaaag cttcgagaaa aaacatcaac
      781 atgttttaag agatattgat gcactaaaaa aagatgtgtc caattttgga cagatgtttg
      841 tagaaggtaa tgaaccagat tcatatggca gaaatcgacg agttttcttc attagtagag
      901 atggattttt cttgctggct atggggttta caggaaagaa agctatctac ttcaaacaaa
      961 aatacattga agcattcaac gaaatggaag atgttattcg caagaatact gttcctcaaa
     1021 caattgaaga tatgatgatc tatcaattag aagaaatgaa agatgttaaa aaagatgttt
     1081 ccatgcttaa agatactatg cgaattagcg gacaacaaga gtttgaaatt aagcaaaaag
     1141 gaaatatgaa agttatggga gttctagggg gaaaagaaag ccgagcttat gaagaaatca
     1201 gcaaaaaagt attctcaaaa ttttggtctg aatttaaacg taccttttca atcccaagat
     1261 atggcgagtt acctcgtaag agattcgatg atgctgtttc atttattgaa atgtggttgc
     1321 cagaaactgc gatccgtatg gaaattgatc aactgaacag acaacagaga ctttttggtg
     1381 atgacaatga atagagctga agcgctaaga atagggacgg caattgctaa ttgctggtgg
     1441 aaatactata aaccaatcat cctaagccaa caacatattg acaagcaaaa agcatggcaa
     1501 caaataaaaa agtgactccg ccggcaagca aagagtcaca aagaaaacac atcataagga
     1561 gattttagca tatggaaaaa gaactttcca ctctagatca atatttgatt gatcctgatt
     1621 ggggcaagcc gaaaattgag gaaacaagtg gtcgaaaaat cagacgaaat cttttgacga
     1681 atgaagaact agcttgggat caagatgatt taggcaacca tgtaactatt tgggatcatg
     1741 tttatcttat ccatctatcg aagcattcga ataaacctga atatatttac gtcatcgaag
     1801 atggcttgat tgatgcgcta gaagagtacg acagagataa cttgattgat atctcttatt
     1861 acggaccagg taagaaatac attgctgaaa tggaggcaga atttgatgag tgaaatcaaa
     1921 gggacaacga actttgaaaa actttttagt cgtaagttaa ataaaattct caagaaaaaa
     1981 ggaaattttg attatttatc ttgggctcac gcgtgggaga ttatgaaaaa gaatgatcca
     2041 caggcaacgg taactattaa tgagtacaaa cactacaggg ttgtttctgg aactcatcaa
     2101 gactttcttg ttgaggaata taaacctttt cttatggatg aaactgggac ttatgtatct
     2161 gtctcagtaa cggttaaagg acacacggaa accgaattat ttcctgtttt agattatcga
     2221 aaccaaccag ttgttaaacc aaatgcaatg caaatcaata actcattgaa gcgatgcttt
     2281 gtgaaagcat tggctctaca cggactggga ttatatgtat ttcaagggga agatattcca
     2341 acaccaccta gaatcgatac aaagaaatta aacatgctag agacgattct agaagctttc
     2401 aatgagcaga tgggtaaaga tatgaccaaa accttaatcg aatatgttaa tgagcagaca
     2461 gataaattag ggctcttagc tgataacgtt gaaactattg aacagttaag ctatgagcaa
     2521 tgtgccttga tggagcgagc aatagcagct aagagaaaag aattagataa gaagtgatat
     2581 gagtgtttaa accattaatc gattcatatt cagcggttct gaaaaagttc aaaggaaaag
     2641 acataagcgc aaccatcaat gaggaagtga acattgatcg actaaagacg atgtatga
//
LOCUS       DBBGSZ010000099         2490 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.108, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000099 DBBGSZ010000000
VERSION     DBBGSZ010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.108"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(365..1657)
                     /locus_tag="ACIZE5_002790"
     CDS             complement(365..1657)
                     /locus_tag="ACIZE5_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HGC6109877.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(1931..2191)
                     /locus_tag="ACIZE5_002791"
     CDS             complement(1931..2191)
                     /locus_tag="ACIZE5_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109878.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          844 a          465 c          381 g          800 t
ORIGIN      
        1 tatgggctac tctgtgatac ttattagcca ttaaactatt ttacccacat agcatatatt
       61 ttgaaatcgt tcattccgta aattcaacta aatatgccta aaaaaataaa aaatctaaga
      121 tagaataaga tttattcagt cttagatgga tttatagcaa ctttttcgta acaactttaa
      181 aaaatacgaa aagaaagagc tgttttactc tgactacgtt gctaaattgt cgtttaatca
      241 ttcatttaaa ccaaatcttt ttttatagaa ttcgttttaa tcctcctgaa tccaaaaact
      301 atgaaaaccg taattaaata gttaagagtt tttaaccacc ataattctct cggctatttt
      361 gaaatcagat aaattttgat cggacacata gttgaataaa cctaccgttg ttacggaagg
      421 taaatcgcat acttttcatt ctagaggaga aggtctcgtt gatcattaac tgattaagca
      481 ccatagccca gttttgaatt cgaccacctg accacttcgc gtgtaattct ttcgtgcgta
      541 aataaagtag ttttaggagt gcattctcat tagagaacgc tccttttttt gtgacttttc
      601 tgaagctgga gtggacactt tcaaccgcat tggtagtgta cataattttt cgaatggcac
      661 taccataatc aaatagttgt tcaacatgtg caaagttccg tttccagaca tctacagcac
      721 cagaataatg agaccaccga ttttgaaaac tgtcaaaagc agcatgtgca gcgtttagag
      781 aagaagcacc gtagaacttt ttcatatctc ggcagacttc cttatagtcc ttacttggaa
      841 tatagcgcaa tgcatttcga acaagatgaa caatacagcg ctgaacaatt accgatggaa
      901 agatcgcttt tgcgccttct tcgaggccag aaacaccgtc catcgaaatg aaaaagacat
      961 cttcgacacc acgtgctttc agttcatcaa atacttgcat ccagcgattt ttagattctg
     1021 tttgatttaa ccataatcct aaaatctcct tatttccttt gagatcatag ccaagaatgg
     1081 tgtatacagc atattctttg gcttcataat tttctcgtaa agtaacatac atacaatcaa
     1141 cgaatagaaa ggcataacac tttgctaggg ggcgggcttg ccattcttcc aattcaggaa
     1201 ggacagcgtc agtgatatct gaaatcattt catgggaaat atcaaagcca taaatagctt
     1261 cgacggttgc ggcaatatct cgttgactca ttcctcgtgc atacatggaa agaaccttcc
     1321 cttcgatgtc ggagacatct cgttttctct taggaattaa ctctggttca aaggaagctt
     1381 cccggtctct aggaacatca atagctactt caccaaaact ggttttaagc gttttagttc
     1441 catagccatt tcgacggtta tcgtgttcct taggctcttt agaatgggca tcataaccta
     1501 aatgattatt caattctcct tgaagcattt tttcaaaaag gggcccaaac acatctttca
     1561 aagcatcttg catgtcatcg acagattcag gttgataggc attcagaatg gattcagcta
     1621 acttttcggc atcaggattt cttttctttc tagccatcgt gtaatcacct cttgatctta
     1681 ttgtagaaaa agaaaaaccg cgaagcaacc acctgcctag gattaatggt tacttacacg
     1741 gtttatatta cactctcatc attaaaaaag tatctttcga tattactaaa caatgaaatt
     1801 atctatttga aatttaaatc tgataatata ttgagtgttc caatgagggc tttgatccta
     1861 ttatccatat ctttttcagt tttaatattg atacacatta taagaaaaag aaacttttgg
     1921 ttaatttatt tcatcccagt gcaaaatata aaaaagtaaa atagaccata ggcaatagat
     1981 taacaattaa tataatacaa gcaaatattc tattcattgt atttctgctt tcaaaaagtt
     2041 ctaatattga aagtataatt ccacaaatgc ctataataag tatgggaata agattagaaa
     2101 ataacacccc gagccaatct gtgaaaatta ctatatttac taatatccct attaacatac
     2161 ctatcatatt tattaaatca atttttttca ttagatattt ctcctttatt aaatctgaag
     2221 tacttatatt aaaataattc taaactattt acctcaaaaa gtgcaataaa ttatttctga
     2281 acaataaaat gatagtcaaa acaaaaaaat attgttaatc gttcagagcc atccgagagt
     2341 gtaaaatatt ttgtgtaaat gaaaaaatcc atacaaaaaa ggaaggcgct tctgtagaat
     2401 aaagttaacg acaaccaatt cacagaaaag aggacttccc tatgaatgat tttactacag
     2461 aaattgtgca aactctagtc actaaaggcg
//
LOCUS       DBBGSZ010000100         2398 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.109, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000100 DBBGSZ010000000
VERSION     DBBGSZ010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.109"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            207..2069
                     /locus_tag="ACIZE5_002792"
     CDS             207..2069
                     /locus_tag="ACIZE5_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGC6109879.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="ACIZE5_002793"
     CDS             2069..>2398
                     /locus_tag="ACIZE5_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGC6109880.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DBBGSZ010000101         2318 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.110, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000101 DBBGSZ010000000
VERSION     DBBGSZ010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2318
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.110"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(76..1623)
                     /locus_tag="ACIZE5_002794"
     CDS             complement(76..1623)
                     /locus_tag="ACIZE5_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HGC6109881.1"
                     /translation="METTDTLLQLLQEAHKTNQTQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKTDKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1725..2078)
                     /gene="tnpB"
                     /locus_tag="ACIZE5_002795"
     CDS             complement(1725..2078)
                     /gene="tnpB"
                     /locus_tag="ACIZE5_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGC6109882.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2068..2262)
                     /locus_tag="ACIZE5_002796"
     CDS             complement(2068..2262)
                     /locus_tag="ACIZE5_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109883.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          652 a          482 c          413 g          771 t
ORIGIN      
        1 taagcgcccc atagaacagt acctgtacgt caaataaccc gacctataga atagaatcgg
       61 gaatgtttgg cgtttttagt tacgagaaaa atgttgttgt acatccttgt tccaaggcaa
      121 cagttgatct aaagtttctg ctgaaagtac gggaagattt ggtatcttat caaatagaaa
      181 ctctagatac tttacaggat tcaatccgtt aagttctgct gttttatata cactcagaat
      241 gattcctgaa gttcgtgctc cttcaagact tgtggaatgc aaccaatttt tccgtcctat
      301 caccagctct ttgatatttc gctccgcacg attatttgtg agttctaaac gaccatcttc
      361 aaaaataggt tcaaaaccac ttcgtagttt acacgcatat tgaacggctg catccaactt
      421 ggattttgca acaggatcta tcgttgccat ccactcataa aaagcaataa ataatggacg
      481 cagttcttgt tgccgacagc ttaatcgctt ctcaggagaa aagtctttcc atttcttttc
      541 taggacaaac catttatcca attgtttgac tgcttgagct gcgggaatat ccgtgttttt
      601 ctttcctttt ggaattgctt cgaaaaattt ccgccgaaca tgcgcgaaac aatagacaag
      661 tcgtacactt tccacggcat tatacccgct atagccgtca cagtgtaaat accctgtaaa
      721 ctccttgaga aaagttttcg gaacatctcc agcacgactt tcgtcgtggt gataataaac
      781 gatgggatgc tgactgtctt ttcctgtaca aaactgccag taataggtat ctgttttggc
      841 actttcaatc acacgataac ttgtttcatc cccgtgtaga atctcttctt gattaagata
      901 gactcttaat cgttctccta aagggtctaa cgcgttttgc actgctttaa tatgccaatt
      961 ggtgatatta tctctcgaaa tatccaaccc atgtgtttgt ttccaatagt tctcttgccg
     1021 ataggcagga actttctgac caaatttcat ccggatcgtt tccgccacta aactattgga
     1081 acctaagcta ttagaaatca aaggtttagg aacgatcgct tttttaaaag aagaaagtcc
     1141 ttctttttcg cagcttttac aacaataggt atgttgataa tgggtgagac aatccaacat
     1201 agcctgatgg aaacgaattt cttctcgtac ttttgtccgt ccgatatctt tcatctgtga
     1261 accgcaatgt tcacaaaatt gttcttccaa aggaaggaga tgttctttct ctgttatagg
     1321 taagtgtttg attttgtctg ttttcgttcc tacaactcgt tgatgtcctt ttactggaat
     1381 aatggtggca gctgcttctg gaacacttac agaaatttct tcatcactaa aaagattcaa
     1441 ttgcccattc gtttcttcaa agagagtctc tttagagcgt ccaaataatt tgttggttaa
     1501 ataattgacc ttttcattca atagttggat ttcagttgta agattctgaa tggtttgttg
     1561 ttgtgtttga ttggttttat gggcttcttg aagcaactga agcaacgtat ctgtagtttc
     1621 caaaattttt caccaccttg aatcgaactg attttgttac agaataccac aagaaacgca
     1681 caagaaatag gggttcaaca cattttttgt gttaaccccc cagcttaaaa aactcctttt
     1741 tttcctggca aaatagctcg aggttgatcg atacttaatc cttctaacaa ccatcgaacc
     1801 tgttggttcg ttaaggttcg aacttcgtct ttcgtccgag gccattttaa cttgccgttt
     1861 tctatccgct tataacagag aagaaaacca tcaccgtccc aatagagaag tttgaaacgg
     1921 tcttgacggt tcccgcaaaa taaaaaaacg gcatcttcgt aaagctcgag ttgatactct
     1981 tgttgaataa gactggcaag accatcaatt ccttttcgca aatctgtttt tccgcacaca
     2041 atataaatat gtttggtttg aagtaaatca taaagcattg gacaacagtt ctttcaaaat
     2101 agcttgaaga atataattgt taataccgtt atagatcaaa acttcagaac cattctctct
     2161 tttgatgcgc atcgctaact tggcagccgc gggtttacct ttttctggtg cactcttttc
     2221 gtttcctaat tggacaggaa caatctcatt taatttatac atagaaaacc tccagacttc
     2281 ttgatagctc aagtatatct tgaggtgcat ttgttagt
//
LOCUS       DBBGSZ010000102         2270 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.111, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000102 DBBGSZ010000000
VERSION     DBBGSZ010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2270
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.111"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            191..445
                     /locus_tag="ACIZE5_002797"
     CDS             191..445
                     /locus_tag="ACIZE5_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGC6109884.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            446..763
                     /locus_tag="ACIZE5_002798"
     CDS             446..763
                     /locus_tag="ACIZE5_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGC6109885.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1322..2257
                     /locus_tag="ACIZE5_002799"
     CDS             1322..2257
                     /locus_tag="ACIZE5_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109886.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          823 a          307 c          429 g          711 t
ORIGIN      
        1 gatgttaacg gaagtgtatg gtgagtagtt cactcgtatt ttgatatcgt ttgtatatgt
       61 tttcagcgtt ctaagtggct tattttgtcc aataataata tggagtggaa tcccttaaga
      121 aacaccgttg gcaattgttg ttataacatg ttataattta ttcatcaaaa actaaaagga
      181 gtgtgataac atgggaaaag aactaaaggt tagaaagatc ggcaatagcg tgggagtgat
      241 ccttccaagc tctcttggat taaaaagcgg agacattatc caagccaaac aagaaggcaa
      301 cttattcata ttagatacta ctcaaatagc aaaagaacac gatcgcaaat tgattgaaga
      361 aagtttccaa gactttgaga aaggtttaac agtttcagaa attgaaatgg taaaagcttt
      421 cggaaaatac ggctggagtg aatagatgaa agagtacacg ctagtttatt ctaaaagttt
      481 tcagaccagc cttgaaacga taatagaaga atgggaaaat gagcttgctc tttctccagc
      541 cagcataaaa agatttgtag gtgcgatcca gaaggcttta gaactaacca aaaattttcc
      601 aactatgcat gaggaagttt ccgaaatcta tggaatggat atcccaacat atcggatcgt
      661 gatcggcaaa agctatgcct tattttatcg gatcgaccat gaaaaaaaag agatacttgt
      721 aggacgtatt ttccaatcta aacaaatgaa actaggcttt taacaataat taggaaaaag
      781 tcgctcatcc tctacaggtg ggtgattaat gccgctcgat atggttgtta accgtcggtt
      841 actcgaagat tgatatataa gacttagtac ctttttattt tgctccatgt tatggccgaa
      901 ggtctaaaga tacaatcatt agtctagaga aaaattaaga accgtaggaa ctacggggat
      961 cgcttggtga ataagagaca ctgctattag tgaaaaaata agatatcaag tacgctctat
     1021 tcccaaaaat ttcgtgactt tactcatgag aggttcaagt agtatatttt taatcaaaat
     1081 tgacgtaact tttaataaat actacctaaa taaggtagta tttatttttg tgttttaaaa
     1141 gaggaagtcc aatatatcta tgggaaactt cttaaatatt atgttggtac atgaaaatat
     1201 acatccctgc tagactattt acaacatttt actttgtacg tattcttgtt ttaaaaggaa
     1261 tgggataaaa tataggtaca ataactattt gatgctaaat ataattaatg gaggagagat
     1321 agtgaacata cttaatgaaa aaagatatgt atggtttgct ggtaaaaaat atattactac
     1381 tttcaaaaga ttatccgagt taatgcagca gactgttaaa agtgctatgc ctgaaggata
     1441 caagtttaat tttgttcaat cttcagtatc tactgaaagt atctattttt caattctttc
     1501 tgagagtagg ctttttcatt ttagaataag ttctcatgta aagaaaactg atgttgatat
     1561 atatacgttc cgtacaaata attataaaaa tttaaatgat ttgagtagaa gtatcagtga
     1621 atatctcaag gggaatagct atctcaagat tcgattttca catatattaa ttttactacc
     1681 atatttgaat gagaatttca ccctaattca agtagataag tctttcattg cctcaggtaa
     1741 tcaaggaaat atgaatatta caagtaacaa aacgtcacgt gtgctattgg cgttgatggg
     1801 ttacggaatt ctttatagag atgaccaaaa tggccagatt ctaataaatc gggctgggcg
     1861 ttcattatta atgaaatata gaaaatttat accggaagat tttcaaaact tacagttaga
     1921 aaacatgcgt ttagaagatt tatttagatt agcagaagat gataagtata gatttgaagt
     1981 tttgaaaatt caaaagaatg aactattgaa taagttatat cctgagaatg cgataaaagc
     2041 acattttggt gatgctaatc atatgtatag ttggttcatt cctaaaagat ttagagggaa
     2101 aatcaatgct ggagatcaag tgaaagtact caatcgaaat agtacagatg tcgtaatgat
     2161 aacagatatc tatgtagaag atgaagatat aatcaaatat atgaagcctg tgataaaact
     2221 tgttaataaa aataaaggaa cccgtggtgc tagttaattt tttcctagag
//
LOCUS       DBBGSZ010000103         2125 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.112, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000103 DBBGSZ010000000
VERSION     DBBGSZ010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2125
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.112"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..159
                     /locus_tag="ACIZE5_002800"
     CDS             <1..159
                     /locus_tag="ACIZE5_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HGC6109887.1"
                     /translation="RRNKFYRSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEI
                     KVLMGIPA"
     gene            242..859
                     /locus_tag="ACIZE5_002801"
     CDS             242..859
                     /locus_tag="ACIZE5_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109888.1"
                     /translation="MWIFKQEIFAKLFSLDGLGWGILFFIFLFLGSMWIWFVDKKNSY
                     EKVIVKKMNRNEFDDFSKEHRVELYDSHEINSTSPSYYWVFGCEEKPLEIKLLKMLEN
                     PPVIEDFSAKNVEKQMFEQVQIRGQNKISLEPDEYAAFFLETNSGTSMPVFKVKLKMN
                     GRLCTYDLVANMRYGSTGDRRTILKFEQTFRSFLKNRVSQIFNLD"
     gene            1023..1355
                     /locus_tag="ACIZE5_002802"
     CDS             1023..1355
                     /locus_tag="ACIZE5_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109889.1"
                     /translation="MNNREILAKEMADLKAKEAKIRAKRKQIRQKEMISLAKLYCKKE
                     GFKTPAEALDFLESNKRNHSVNDEVLVSLRKFADGLVWQENGAYWRTNDVKGLTQFMA
                     QFRSENVN"
     gene            1679..1840
                     /locus_tag="ACIZE5_002803"
     CDS             1679..1840
                     /locus_tag="ACIZE5_002803"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HGC6109890.1"
                     /translation="MAYMVARTQKHKVGSLNGLQNHVDRKTKNHTNKDIDITKSGSVA
                     KFSKKSILV"
     gene            1872..2125
                     /locus_tag="ACIZE5_002804"
                     /pseudo
     CDS             1872..2125
                     /locus_tag="ACIZE5_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
BASE COUNT          758 a          272 c          429 g          666 t
ORIGIN      
        1 cgacggaata aattttatcg aagtctccgg actgcctcat ccacgattaa ggggatggag
       61 accattcgag gaatatataa aaagaaccga agaaatggaa cgctcttcgg cttttcggtg
      121 tctactgaga tcaaggtatt aatgggaata ccagcctaag atatttggag ttcagagagg
      181 gcgcgtttga ttttcaaact tcgcaacaga accattattt taaagtggga ggaaaattgt
      241 tttgtggata tttaaacaag aaatctttgc taaattattt agtttagatg gattaggttg
      301 gggaatctta ttttttattt ttttattttt aggatctatg tggatctggt ttgttgataa
      361 aaaaaattct tatgagaaag taatagtgaa aaaaatgaat cgaaatgaat tcgatgattt
      421 ttcaaaggaa catagagttg aattgtacga tagtcatgaa attaacagta cttctccatc
      481 ttattattgg gtatttggtt gcgaagaaaa accattggag attaaattgt tgaaaatgct
      541 tgaaaatcct ccagtcattg aagatttttc tgcaaaaaac gttgaaaaac agatgtttga
      601 acaggtacaa ataagaggtc aaaacaaaat ttcattagaa ccagatgaat atgcagcctt
      661 ttttttagaa acaaattcag gtacttcaat gcctgttttc aaagttaaat taaaaatgaa
      721 tggtcgttta tgcacttatg atcttgttgc aaatatgcgc tatggttcta ctggtgatag
      781 acgtactatt ttaaaatttg agcaaacctt tagaagtttt ttgaaaaata gagtatccca
      841 aatttttaat ttggattgaa aaaattaaaa atttggccaa aaatactaca gttttttaga
      901 gcaatcatct tatgatgatt gctctttttt tgttgttttt gtgtcattcg ttgttcaaat
      961 cctctattcg taaaataaat attttaaact agaaatatgc cttattttta ggaggaatca
     1021 aaatgaacaa tagagaaata ttggcaaaag aaatggcgga tttgaaagca aaagaagcga
     1081 agattagagc gaaacgaaaa cagattagac agaaagaaat gatttcttta gcgaaattat
     1141 attgtaaaaa ggaaggcttt aagacacctg ctgaagcatt agattttttg gaatcaaata
     1201 aaagaaatca ttcagtaaat gatgaggttt tagtatcgct aagaaaattt gcagatggat
     1261 tagtttggca agaaaatggt gcatattggc gtacgaatga tgttaagggt ttgactcaat
     1321 ttatggcaca atttcgttca gaaaatgtga actaaattga ggaggggttg aagtgaaaag
     1381 caatactttt cacttttggt tttttgcgga ataaaaattg tgaaaacaat gacgcaaaaa
     1441 gccaatggtt ttgaacgaaa aaaggacgta aaaaaggaat gcgaaggcag tcgtttttcg
     1501 ttcgcttttt cgtttgagag aaacggagtt tctcatcggc tgttaagccg atatagccct
     1561 cggcagagct tacagacttt acgcagtata agtctagtaa gttatacctt acatggaggt
     1621 ttttccgaat ttagcttgtg attctcgcaa taattttaac gaaaggaagt acacagttat
     1681 ggcctatatg gtggcacgaa cacaaaagca taaagttggg tcgttaaatg gacttcaaaa
     1741 tcatgtagat cgtaaaacga aaaatcatac gaataaagac attgatatta cgaaaagtgg
     1801 ttctgttgca aagttttcca aaaaatctat tttagtgtaa aattgagaaa aaagacagag
     1861 aggatagagt aatgaatcat tttaaaggca aacaattcaa aaaatgacgt cattattgtc
     1921 gctgttagtt actacctgcg ttacaatcta agctatcgtg aagttcagga attgttatat
     1981 gatcgtggaa taaatgtttg tcatactacg atttatcgtt gggtgcaaga gtacagcaaa
     2041 gtcctcgatt atctttggaa gaagaaaaat agacaatcct tctattcatg gaaaatggac
     2101 gaaacctata tcaaaattaa gggac
//
LOCUS       DBBGSZ010000104         2089 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.113, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000104 DBBGSZ010000000
VERSION     DBBGSZ010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2089
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.113"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            28..987
                     /locus_tag="ACIZE5_002805"
     CDS             28..987
                     /locus_tag="ACIZE5_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC6109891.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSVASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            complement(1110..2084)
                     /gene="bsh"
                     /locus_tag="ACIZE5_002806"
     CDS             complement(1110..2084)
                     /gene="bsh"
                     /locus_tag="ACIZE5_002806"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HGC6109892.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          730 a          355 c          321 g          683 t
ORIGIN      
        1 ccaaagaatt ataaggagtg agtacaaatg acctataccc atcttacaac ggatgaactt
       61 gtaataatag agtcttattt caaaatgaat caatctgttg ctaaaactgc ccattgcttg
      121 aatcgttcaa gacaaacgat ccataaagta tatctgttct tcaagcaagg aaaatcagcc
      181 ttagaatatt atcaacagta taagaaaaac aaatcaaact gtggtagacg tccgcttgtt
      241 ttacccgagg aacaatcaga atatattcaa agaaaggttg ttcaaggatg gacacccgat
      301 gtgattgttg gtcgtgcagc gtttcctatt agttgttctg ctcgtaccat ttatcgtatg
      361 ttcaaaaagg ggctatttga ttcttctgac ttaccgatga aaggcaagcg taaaccgaat
      421 ggacatcaag aaagacgtgg aaaacaaact ttccgccgct ctattcatga acgtgaaaag
      481 gattatagcc aattctcaaa tgagtttggt caccttgaag gtgacactat cgtaggtctg
      541 aaacataaaa gtgctgtaat taccttagtt gaacgattat caaaagttat catcacattg
      601 aaaccgtgtg gtagacaagc gattgatatt gaaaaaaaat taaatcaatg gtttgaatct
      661 gtaccgaaaa acctattcaa atccatcact tttgattgtg gaaaggaatt ttcaaattgg
      721 aaacagatca gtaatgtcaa tgatattgcc atttatttcg ctgatccagg aacgccgtct
      781 caaagaggcc taaacgagaa ttctaacgga ttgttacgta gagatggttt attgaaatct
      841 atggatttca attcagtaga tgaatttttt attcaatctg tcgcatctaa acgaaataat
      901 attcctagaa aatcactgga ttatcgaaca cctttggaag tatttttgag ttacgtaagt
      961 attgatgatc tgtctaactt aatttgacaa ttaagaagtt aaaaacatta caaaaaagac
     1021 aaggatatca catcaagaaa aaatgttttg aaaatatctt tgcctttttg tattatatct
     1081 atattaaata atcaatcaca acacattaac taatttatat atttaatttg ttgtttttct
     1141 ataattggat aactaattaa cttatgacta tctaagtctt ctttattcat atcaattgca
     1201 gtaatttgac tgtcttcata tgttcgataa taatagattc ctttgtcaac attgcaacaa
     1261 gaagaataaa ttgtatattc atattttcca tcaccaacat cacacaaacc tttttgttgt
     1321 tctactgaac ctaagatatg gaaaaattga ctaatacttt ctgactctga atctccagat
     1381 acagaattca gcttcgtaaa agtcgcttta acaaaacgag atactgagga taaatctcca
     1441 ggcaagccta tccctcccat accgcggcta taggcattca aacttatttg atttgaaaaa
     1501 ttatttttag gagtttcact cgataagaca cgataattgt ttaaattaaa taattgatag
     1561 tcaaatgaag gattattggt aagaacgccc acagggttat catatatatg aagtccatct
     1621 ttcatacttt caatgacaat tgatttttct ttatcagcta atagccaatg taaaggggat
     1681 aaaggaagtt catcactata atttatattt gctaaattga tattttttaa caatttttta
     1741 gtttctccta ctgttgagca ttgtcctaaa atccaaggaa taaattcaaa aggagataca
     1801 ttgtctttcc cttcttgtat ttctttataa tcagcatacc cagaaaaatt tagcccagcc
     1861 atactcaatc ctttttcatt tgtcgcatcg taataaagag ggtagtcagc tataccagcg
     1921 gcaataccaa tcattgcata atgagtatcc aaatcattta cctttcgaaa attcaactta
     1981 taatttcttg gagtaacagt aactacttca ttgtaagata tttcataatc aaaattcctt
     2041 ccaaaataat gatcacttgt tacataagta atagacgtac acatagttt
//
LOCUS       DBBGSZ010000105         1930 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.115, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000105 DBBGSZ010000000
VERSION     DBBGSZ010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1930
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.115"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..977
                     /locus_tag="ACIZE5_002807"
     CDS             <1..977
                     /locus_tag="ACIZE5_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGC6109893.1"
                     /translation="LFLLPINGFAYTINNEFNLGANEGSSQVANNQYILLHETANETA
                     TGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGSYANANSPVQIELQHT
                     HDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHLWVTQNIWGDHTDPYG
                     YLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNYAHIDQF
                     GEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRADVNQAYNTSGNVG
                     YHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
     gene            1166..1239
                     /locus_tag="ACIZE5_002808"
     tRNA            1166..1239
                     /locus_tag="ACIZE5_002808"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1200..1202,aa:Ile,seq:cat)
     gene            complement(1754..>1930)
                     /locus_tag="ACIZE5_002809"
     CDS             complement(1754..>1930)
                     /locus_tag="ACIZE5_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HGC6109894.1"
                     /translation="NLYYSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYD
                     YIKYTFVDPERYKD"
BASE COUNT          635 a          336 c          360 g          599 t
ORIGIN      
        1 ctcttttttt attgccaatt aacggatttg cctatactat caacaatgaa tttaatttgg
       61 gcgcaaatga aggtagctca caagtagcaa ataatcagta tattttactg catgaaacgg
      121 ctaatgaaac agcaacagga cgcaatgaag cgcagtatat gcaacgttca tggactagcg
      181 cttatactgc ttatattgtg ggagacggcg gaattgttta tcaagtcggt caacctggtt
      241 atgtacagta cggtgctggt tcgtatgcta atgccaacag tcctgtgcag attgagttac
      301 aacacacaca tgataaagca acgtttgaga aaaactacaa ggcatacgtt gaattggcta
      361 gagattcagc aatgaaatat ggtattccat taacgttgga cactccttat aaccaaccgg
      421 gaatcaaatc gcatttatgg gtaacacaaa acatctgggg cgatcataca gatccttacg
      481 gttatctttc tgaaatgggc gtaagtaaag aaaaattagc atatgattta gctcatggat
      541 ttaccgatga aaatccaaca acttctgaaa acaagcctgt cattgatcca acacgagctg
      601 gtgcagctaa tcctacactg acagatggaa cgaattacgc ccacattgat cagtttggag
      661 aaatcgaaaa tgcaaatttg catgtagctg gatggcacat tgctaactat aaatacgagt
      721 atatcttcat tatggattac aatactggga aagaattagc tcgagtaaga gctgatggaa
      781 tttatagagc agatgtaaat caagcttata atacttctgg aaatgttggc tatcatgtat
      841 cttttaacat gcgtaacttc cctaataaga aagtctatgt catgatgcgg gcaacgaatg
      901 atccagaggg aaacactaaa ggcggtgcgc aagatttcca tgacaaacgt tggtatttaa
      961 atattcctaa acgataaaaa tagctcctcg ttgaggagca ttacataact atattgacaa
     1021 ctataaaaat cattcgataa aatagtgatg ttatcgcata tcttcactat cacccataat
     1081 agtcacactc caagctatgc gataacaggt ttgttgccac acattctact ggttgattgt
     1141 ttatggcttt atgtggcaac aaccagtacc cttagctcag ttggtcagag cagacggctc
     1201 ataaccgtcc ggtcgtaggt tcgagtccta cagggtacat taacgtagcc atttgaatcg
     1261 ttctgtgtta gaattttttg aagagtatta tacaagctaa agcttttctt cattgccact
     1321 caaatgagtg gcttttttat gtatcctttt atggattaat gaaaggatgt ttcacatagt
     1381 tatatttctg tatatttgaa aagttttact ttgattttta aatagaaaga catttgggtt
     1441 atattgtgag ataataataa agaagagttt aaagcgttcc ccaaaaacca ctgccccata
     1501 agtgtgttac gctttaaact cttttatatt tgaagccatt aaaaagcata ccatattttt
     1561 gaaaaaaagt gagaaaaaag gcttataatt ggagtggtag ttaattagtg acttattttt
     1621 gattttatag cactgatact ataaaatata gatatcatca tattacacaa tcttaatact
     1681 aacttaaaaa atatctcctt tcataagtat ggtgataaaa tccgttccgg gctacctttt
     1741 taggtagcct actttaatct ttgtatcttt ctggatcaac gaaagtatac tttatatagt
     1801 cataacgccg atgatcgctt cgagcgtcta gcacatcagt cacgatatca aacaaaaaat
     1861 atacgtcttt cttcattcta gttttcgcag cagggatttt aaagtagttc ttattagaat
     1921 agtagagatt
//
LOCUS       DBBGSZ010000106         1847 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.116, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000106 DBBGSZ010000000
VERSION     DBBGSZ010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1847
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.116"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..983
                     /locus_tag="ACIZE5_002810"
     CDS             <1..983
                     /locus_tag="ACIZE5_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="peptidoglycan recognition family protein"
                     /protein_id="HGC6109895.1"
                     /translation="LFLLPINTFAYTINDEYNLAPNQGDSRLAIPNKIILHETGIDAP
                     ARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAGNANPYAPVQIELQRT
                     YDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIISHLWVTNYVWGNHTDP
                     YGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNHAHID
                     QFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGN
                     VGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
     gene            1173..1246
                     /locus_tag="ACIZE5_002811"
     tRNA            1173..1246
                     /locus_tag="ACIZE5_002811"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1207..1209,aa:Ile,seq:cat)
BASE COUNT          607 a          319 c          346 g          575 t
ORIGIN      
        1 ctcttttttt attacccatt aatacgtttg cttatactat taatgacgag tataatttag
       61 cgccgaatca aggagactcc agattagcaa ttcctaacaa aattattttg cacgaaactg
      121 gaatagatgc accagcaaga aacgtagccg ccaacatgaa aaataattat aacggaagca
      181 attcttatac tacagatgtt attggtgacg gtgggattgt ttaccgtgtg ggtgagcaag
      241 gatatgtttc gtggggagct ggtaacgcta atccttatgc gcctgtacag attgaattac
      301 agcgcacata tgataaagca ttgtttgaaa aaaactatcg agcttatatt gaatatacaa
      361 gagatagtgc aaaaaaatat ggaattccat tgactcttga tcaaggaact tctttattta
      421 caaaaggaat catttctcat ttgtgggtga caaattatgt ttgggggaac cacacagatc
      481 catatggtta cttatcgcaa atgggagtta gcaaagaaaa gcttgcttat gatttagctc
      541 atggatttac cgatgaaaat ccaacaactt ctgaaaacaa gcctgtcatt gatccaacac
      601 gagctggtgc agctaatcct acgctgacag atggaacaaa tcacgcccac attgatcagt
      661 ttggggaaat cgaaaacgca aacttgcatg tggctggatg gcacattgct aactataaat
      721 acgagtatat tttcattatg gactacaata ctgggaaaga attagctcga gtaagagctg
      781 atggaattta tagaccagat gtaaaccaag cttataatac ttctggaaat gttggttatc
      841 atgtatcttt caatatgcgt aattttccta gtaagaaagt ctatgtaatg atgcgggcaa
      901 cgaatgatcc agagggaaac actaaaggcg gtgcgcaaga tttccatgac aaacgttggt
      961 atttaaatat tcctaaacga taaaaatagc tcctcgttga ggagcagtac ataactatat
     1021 tgacaactat aaaaattatt cgataaaata gtgatgttat cgcatatctt cactatcacc
     1081 cataaatagt cacactccaa gctatgcgat aacaggtttg ttgccacaca ttctactggt
     1141 tgattgttta tggctttatg tggcaacaac cagtaccctt agctcagttg gtcagagcag
     1201 acggctcata accgtccggt cgtaggttcg agtcctacag ggtacattaa cgtagccatt
     1261 tgaatcgttc tgtgttagaa tttttttgaa gagtattata caagctaaag cttttcttca
     1321 ttgccactca aatgagtggc ttttttatgt atccttttat ggattaatga aaggatgttt
     1381 cacatagtta tacttctgta tatttgaaaa gttttacttt gatttttaaa tagaaagaca
     1441 tttgggttaa attgtgagat aataataaag aagagtttaa agcgcacccc aaaccacttc
     1501 cccataagtg tgttacgctt taaactcttt tatatttgaa gccattaaaa agcataccat
     1561 atttttgaaa aaaagtgaga aaaaaggctt acaattggag tggtagttaa ttagtgactt
     1621 atttttgatt ttatagcact gatactataa aatatagata tcatcatatt acacaatctt
     1681 aatactaact taaaaaatat ctcctttcac aagtatggtg ataaaattcg ttccgggcta
     1741 cctttttagg tagcctactt taatctttat acctttctgg atcaacgaaa gtatacttta
     1801 tatagtcata acgccgatga tcgctacgtg cgtccggcac gtcagtc
//
LOCUS       DBBGSZ010000107         1680 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.117, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000107 DBBGSZ010000000
VERSION     DBBGSZ010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.117"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            64..972
                     /locus_tag="ACIZE5_002812"
     CDS             64..972
                     /locus_tag="ACIZE5_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HGC6109896.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            972..1592
                     /locus_tag="ACIZE5_002813"
     CDS             972..1592
                     /locus_tag="ACIZE5_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109897.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
BASE COUNT          602 a          246 c          377 g          455 t
ORIGIN      
        1 cagtattata gtgcaagtgc aatttcttcc attgtcatac caccaaaata gggaggtgat
       61 ttaatggcaa agtggaatgt catattaagt acaacagaac cctataatta cgtggggatg
      121 attcaagttc gacaaggcaa taagaataca gaggttatgg aagcgactat agttgaaaat
      181 ggtcttccct acgatttatc agaatgtaag gtatattttg aatcagttgt aggtgggaaa
      241 tatccagtcc aattagaaac aaaaattgtg gatgctaaaa aagggaaaat taactatatt
      301 tttgataaat attccatgca gtgtttacat cgacaaacag ccaatttcat tatatttaaa
      361 ggagaagact tgattggaac aactcaagac ttctcttatt ttgtcattaa tgctgtttca
      421 aaaacagaag gagaaatggg ttcttattgg caatcaatcg aagatttaat tgcggatatg
      481 acggacttta ttaatgaaaa taaaggcgat tttacggact ggatgaatga aaggaaagaa
      541 gaatttgaac gttggagaca agaacaggaa cacagtttcc aagattggag agaaggacaa
      601 gaatcagact atttggcatg gtttgaatca atcaaggata ttttaaagac gattgatcca
      661 ggtggagtca tgttagccga actaacggat gcgcgagtag atattcaagg agttcgtcat
      721 gcgtctattt cagagcgttt gctggcagat atggactatt tatatcagaa attgcgagca
      781 acgcttttca cgattgaata cggggagatt gaagtgactg atattttgca ggatgatctc
      841 ttttcagata atcatgaagt cgaaaaagtt ggaactgtag cattcccgat tgaagaagga
      901 gccttgatca tcgcaaccgt tgatgatcca aagcaaaatg tgttcactct tgagaaagtt
      961 ggggtgatct aatggctaaa actaaacgaa tgatggaaac ggatgaaaaa acgggtgtac
     1021 aacgccaatt ctttccaatc acacatgctt ccgcagttct tgggttagaa gaaataatag
     1081 caggagaagc aacagtttta tctgttaatg gaaaaattgg agccgtcgtc attactaaag
     1141 aagatttggg attagagaat gttctcacag aattacccta tgcaagtgaa gaagatgacg
     1201 gcattatcac ggcagaaatg tatcaaaaaa ttttaaacag tggagaaggt gactacgtgt
     1261 tgccagttgc cactatcgac cgtttgggtg gcataaaagt tggtgaatta ttgacgattg
     1321 atgagacagg gaaagtctct gcagtcagac aatctgatgt caatttttcg ctggagttaa
     1381 aagaaaaact cgattcactg aaaaattata ctgctggaga aaacatcact attgatgaag
     1441 atggaacaat tagttctaca ggtggtagtg ggactggtgg tgtcaatcag tcatatgtag
     1501 atcaaaaatt ccaagaagct gtaaatcaag cagaaaatta cacaaacgaa agaattccaa
     1561 attttacttt tgaaaaaatt ggggaggtat agagaatgac agatatcgta aaaataaaac
     1621 aaagcaatgt acaggtttat ccacaaactc attggaatgc tatagaaggc aaaccaacaa
//
LOCUS       DBBGSZ010000108         1677 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.118, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000108 DBBGSZ010000000
VERSION     DBBGSZ010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.118"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            64..972
                     /locus_tag="ACIZE5_002814"
     CDS             64..972
                     /locus_tag="ACIZE5_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HGC6109898.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            972..1589
                     /locus_tag="ACIZE5_002815"
     CDS             972..1589
                     /locus_tag="ACIZE5_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109899.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
BASE COUNT          620 a          226 c          348 g          483 t
ORIGIN      
        1 cagtattata gtgcaagtgc aatttcttcc attgtcatac caccaaaata gggaggtgat
       61 ttaatggcaa agtggaatgt catattaagt acaacagaac cctataatta cgtggggatg
      121 attcaagttc gacaaggcaa taaaaacact gaagttatgg aagctacaat tgtcgaaaat
      181 ggtcttccat atgatttatc agaatgtaag gtatattttg aatcagttgt tggcggaaaa
      241 tatccagtcc aattagaaac aaaaattgtg gatgctaaaa aagggaaaat caaatatatt
      301 tttgataaat attccatgca gtgtttgcat cgacaaacag ccaatttcat tatatttaaa
      361 ggagaagact tgattggaac aactcaagac ttctcttatt ttgtcatcaa tgctgtttca
      421 aaaacagaag gagaaatggg ttcttattgg caatcaattg aagatttaat tgctgatatg
      481 acagatttta ttaatgaaaa taaaggcgat tttacggact ggatgaatga aaggaaagaa
      541 gaatttgatc gctggagaga ggaacaggag aatagtttcc aagattggag agaaggacaa
      601 gaatcagatt acttgtcatg gtttgaatca atcaaggata ttttgaagtc tatcgatcca
      661 ggtggagtaa tgttagccga attaatggat gcacgtgtag atcttcaagg tgtacgccat
      721 gaatcgattt ctgaacgttt cctatccgat ctaaattatt tgtatcaaaa aatgaaagca
      781 gcacttttca cgattgaata cggtgaaatt gaagtgactg atattcttca agacgatctc
      841 ttttcagata atcacgaagt cgaaaaaatt gaaacagtag aatttccaat tgaagaagga
      901 gctttgatta ttgcaactgt tgatgatcca aaacagaatg ttttcactct tgagaaagtt
      961 ggggtgattt gatggttaaa gtaaagagaa tgatggaaac tgatgaatct ggtgttaaac
     1021 gtcaatttat gccaattaca catgtctctg cagttttagg cttagaaaaa atgatatcag
     1081 gacaatcaaa agttctttcg gttaatggta aatatggtgc agtcatttta acgaaagctg
     1141 atttaggatt agagaatgca attactgaac taccttatgc aagcgagaca agcgatggta
     1201 ttcttactgc tgaaatgttt caaaagatcg taaatggaga aggtggaaca tatattttgc
     1261 cgattgctac tcctgaacaa ttaggaggta taaaagttgg ggaactctta gaagttactg
     1321 aagaaggtgt tttatctgca actaagcaaa cagacttcaa tttctctgaa gaattaaaag
     1381 gaaaattaga atctctaaaa atattaaaag caggtgcaaa tatatcaatt gcagaagatg
     1441 gaacaattag ttctacaggt ggtagtggga ctggtggtgt taatcagtca tatgtagatc
     1501 aaaaattcca agaagctgta aatcaagcag aaaattacac aaacgaaaga attccaaatt
     1561 ttacttttga aaaaattggg gaggtataga gaatgacaga tatcgtaaaa ataaaacaaa
     1621 gcaatgtaca ggtttatcca caaactcatt ggaatgctat agaaggcaaa ccaacaa
//
LOCUS       DBBGSZ010000109         1627 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.119, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000109 DBBGSZ010000000
VERSION     DBBGSZ010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1627
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.119"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            221..655
                     /locus_tag="ACIZE5_002816"
     CDS             221..655
                     /locus_tag="ACIZE5_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGC6109900.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            678..998
                     /locus_tag="ACIZE5_002817"
     CDS             678..998
                     /locus_tag="ACIZE5_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109901.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            1139..1330
                     /locus_tag="ACIZE5_002818"
     CDS             1139..1330
                     /locus_tag="ACIZE5_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109902.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(1401..>1627)
                     /locus_tag="ACIZE5_002819"
     CDS             complement(1401..>1627)
                     /locus_tag="ACIZE5_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HGC6109903.1"
                     /translation="PFFIMISILFYYIKWTKKKFSVLLASLPAVYFTYQIFSFRHWET
                     TSVLITHIIELTLSVIFLIIWIYFLYKNQN"
BASE COUNT          640 a          234 c          335 g          418 t
ORIGIN      
        1 cgttttttgt aacagaatga tgttcgctcg atgtgaaaaa tgatgaggaa tttcacataa
       61 tgcagaaata atgggattag aacaggtgtt ctgatgagaa aagaaatgta taaataactt
      121 gaaagaaatt gcttttgttc atcattttat ttacatattg cgtatatttt ttgtattttt
      181 gcttgagatg ttacaataaa agaaaaagga ggcggttcca atgagtaaaa gataccagaa
      241 catcatggta gcagttgacg gatcaagaca atcgatcaaa gcgttcgctg aagcccttga
      301 cttagcaaag gacaatgaag cccacttatt tatcgtgtca atcatcaaca aagttgagct
      361 gacccatagt gcctatgcct tttcaaaaat ctatgcagat gaaaaacaaa gaacagaagt
      421 agccatgctg aaaaaaatca atgatgccaa agagtacggc attgctgaga tccacgcaat
      481 agttgaaact ggagatccaa gaaatttgat tgccaatgtc atccctggac aagaaaatat
      541 tgatttgatc gttatgggag cgacaggaaa aggtgctata caacaagcat tagttggatc
      601 gaccgcttct tatgtcgtat cacatgcccc ttgcagtgtg ttggtcgtga agtaatgaga
      661 taagggagga atagaaaatg gttcgtcctc aagaagtccg tgcgccaaaa gaaaaaatag
      721 aaattttagc aattattgaa gacggcacac aaacaaagaa gggatactcg atcgctttag
      781 taaagtggaa aggaaaaaaa ggtgttgctc tgagatggga tggagataac caacaagata
      841 aaggattccc tgtcacagct aacggttatc atccagcgtg gtttgttctg cctgataaat
      901 ttatggaatt atacagctat gattatgcaa gagccgcagc atcaatcaaa gcattagata
      961 aattaacaga agagcagaat gaaatggagg aaaaataaaa aagacgaacc aatcagcctt
     1021 tagaaaactg attagttcga ggagtaaaaa tgaaaaaagg ttatttggga tgaaactaga
     1081 ataatgcgta taacttaaat aaaacttaaa gcaataaaat ggcaagaggg tgaggcaaat
     1141 ggaagcagga aaagtattac aggaagtaaa agcactatgt gcagataaaa aatatgaaga
     1201 agcgaaaagc ctgatcgaaa agaacaaaga aaatttggaa gaaaagtacc cgatcgcaca
     1261 agaatttata gaattaaaac aaggaacgat ccttcaccga ttcaaacatt tttttggtat
     1321 aacagaatag aaaaaacgat taaagatcgg cagaaatttg ctgcatcttt aatcgttttc
     1381 tttttaaaca tgcgagggat tcaattctga ttcttatata aaaaatagat ccaaataata
     1441 agaaaaatta ctgaaagcgt caattcgatg atgtgtgtta ttaatacaga cgttgtttcc
     1501 caatgcctaa aagaaaaaat ttgataagta aaatatacag caggtaaaga ggccagtaaa
     1561 actgaaaact tcttttttgt ccattttatg taatagaaaa gaatgcttat cataataaaa
     1621 aaaggaa
//
LOCUS       DBBGSZ010000110         1594 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.120, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000110 DBBGSZ010000000
VERSION     DBBGSZ010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1594
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.120"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..447)
                     /locus_tag="ACIZE5_002820"
     CDS             complement(<1..447)
                     /locus_tag="ACIZE5_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HGC6109904.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDR"
     gene            633..1568
                     /locus_tag="ACIZE5_002821"
     CDS             633..1568
                     /locus_tag="ACIZE5_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC6109905.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT          502 a          269 c          330 g          493 t
ORIGIN      
        1 tcgatcatgg attgagcgct gatactgttg ttttccccgt ttttcctgat ggccattggg
       61 ttttctttta cctttcatcg gtagtgtgtc aatatcaaat attcctttag aaaataaacg
      121 ataaagtgtt ctcataccgc atgaaacaga cctttctttt cgcccgataa tgacgtcagg
      181 cgtccaacca agagtgactt tctctttaat gtaatctact tcatgagcag gtaattgaat
      241 gacttttcta ccacattttt tcttattttc tttatactgg tgccaataat caagagcagt
      301 cttgccttgc ttgaacttat tgactacatt ataaatagtt tgtatagcac gtcccattcg
      361 gttagcgatt tcaaccggct tattatgttg aagataatat gattctatca ttgtcagttc
      421 gtctatggta agatgtttgt aggtcattta tggttacact cctttgtttt ctttcgtcgg
      481 aaatacaatt tgagtgtacc ataaatgcct ttttattttt ctaacttaat tttacaattc
      541 gcgggttata aaaatgaaca ttgcatagta gagattcttt gattatacta attcaaggtt
      601 atatgaaaaa agagaaatga gatggatgat ttatgaaact ttggatgaaa atccttttag
      661 gcgtcgcttt agctctgatt gttgcgttag tgtttgcagg gaattatttt tataattatg
      721 ctgttgtgcc ttctgagaaa gactttttag acgaagatac acctggtaca acacagacat
      781 ccaaagaaac ggatgcacat aaatggttta gttcaaaaga aaaccgaagc gattggacca
      841 tcacttcaaa agacggtctg aaattatcag cgatttatct tcctgctgaa acgaaaagtg
      901 aaaaaacagc tcttgtggct catggctata tgggaaacgc tgaaacgatg accaattacg
      961 caaagatgtt tcatgatatg ggttacaatg tccttgttcc tgatgcaaga ggacatggaa
     1021 aaagcgaagg ggattacatt ggatttggat ggccagagcg taaagactat gtacagtgga
     1081 taaacaaagt gctagaaaac aatggaaaat cgcaagaaat cgttctatac ggtgtcagca
     1141 tgggagcagc aacagttatg atgactagcg gagaaaaact accagataat gtgaaagcaa
     1201 tcattgaaga ttgcggttat tcttccgttc atgatgagct tgcttatcag ctagacgata
     1261 tgtttagtct tccagcattt ccgcttatgc aagtaacgag tctagtgaca aaagtccgtg
     1321 ctggctactt tttcggtgaa gcaaatgcag tggaacaatt gaagaaaaac cagcgcccaa
     1381 tgctctttat acatggagac gaagatacat ttgtaccatt tgaaatgtta gataaggtct
     1441 atcgtgcaac gaagggacca aaagaaaagt atgttgtaaa aggagccgag catgcggaag
     1501 catacaagac agatcctgaa aaatatcagc aagtagtcca acaattttta agccaatatg
     1561 ttcattgaac gagtttaaaa gtaggggatg aaaa
//
LOCUS       DBBGSZ010000111         1425 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.121, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000111 DBBGSZ010000000
VERSION     DBBGSZ010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1425
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.121"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(74..158)
                     /locus_tag="ACIZE5_002822"
     tRNA            complement(74..158)
                     /locus_tag="ACIZE5_002822"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(122..124),aa:Leu,seq:caa)
     gene            complement(176..247)
                     /locus_tag="ACIZE5_002823"
     tRNA            complement(176..247)
                     /locus_tag="ACIZE5_002823"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(213..215),aa:Gln,seq:ttg)
     gene            complement(257..329)
                     /locus_tag="ACIZE5_002824"
     tRNA            complement(257..329)
                     /locus_tag="ACIZE5_002824"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(294..296),aa:His,seq:gtg)
     gene            complement(391..475)
                     /locus_tag="ACIZE5_002825"
     tRNA            complement(391..475)
                     /locus_tag="ACIZE5_002825"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(439..441),aa:Leu,seq:caa)
     gene            complement(496..566)
                     /locus_tag="ACIZE5_002826"
     tRNA            complement(496..566)
                     /locus_tag="ACIZE5_002826"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(532..534),aa:Cys,seq:gca)
     gene            complement(612..683)
                     /locus_tag="ACIZE5_002827"
     tRNA            complement(612..683)
                     /locus_tag="ACIZE5_002827"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(649..651),aa:Gln,seq:ttg)
     gene            complement(695..767)
                     /locus_tag="ACIZE5_002828"
     tRNA            complement(695..767)
                     /locus_tag="ACIZE5_002828"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(732..734),aa:His,seq:gtg)
     gene            complement(770..843)
                     /locus_tag="ACIZE5_002829"
     tRNA            complement(770..843)
                     /locus_tag="ACIZE5_002829"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(809..811),aa:Trp,seq:cca)
     gene            complement(850..930)
                     /locus_tag="ACIZE5_002830"
     tRNA            complement(850..930)
                     /locus_tag="ACIZE5_002830"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(894..896),aa:Tyr,seq:gta)
     gene            complement(932..1007)
                     /locus_tag="ACIZE5_002831"
     tRNA            complement(932..1007)
                     /locus_tag="ACIZE5_002831"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(972..974),aa:Phe,seq:gaa)
     gene            complement(1043..1115)
                     /locus_tag="ACIZE5_002832"
     tRNA            complement(1043..1115)
                     /locus_tag="ACIZE5_002832"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1080..1082),aa:Asp,seq:gtc)
     gene            complement(1125..1197)
                     /locus_tag="ACIZE5_002833"
     tRNA            complement(1125..1197)
                     /locus_tag="ACIZE5_002833"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1162..1164),aa:Val,seq:tac)
     gene            complement(1213..1284)
                     /locus_tag="ACIZE5_002834"
     tRNA            complement(1213..1284)
                     /locus_tag="ACIZE5_002834"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1249..1251),aa:Glu,seq:ttc)
     gene            complement(1299..1388)
                     /locus_tag="ACIZE5_002835"
     tRNA            complement(1299..1388)
                     /locus_tag="ACIZE5_002835"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1352..1354),aa:Ser,seq:gga)
BASE COUNT          412 a          367 c          324 g          322 t
ORIGIN      
        1 atttggaggt aattacataa aaacaaaaaa aatatagcaa ctctctataa gaaagttgct
       61 atattgataa ttataccggc ggccggggtc gaaccggcac gtcctcaacg gacactggat
      121 tttgagtcca gcgcgtctgc caattccgcc acgccggcaa atttaaaaat aataactggg
      181 gtagctggat tcgaaccaac gcatgaggga gtcaaagtcc cttgccttac cgcttggcta
      241 taccccaaga ataaagggcg aatgatggga atcgaaccca cgaatgccgg agccacaatc
      301 cggtgcgtta accacttcgc cacattcgcc atcataaaag atgttattta atttctcaat
      361 aaaaaactaa gatgaagaca tcttagtcaa taccggcggc cggggtcgaa ccggcacgcc
      421 ctcaacgggc actggatttt gagtccagcg cgtctgccaa ttccgccacg ccggcaagtt
      481 gatttattag tactaaggcg gtaaccggat ttgaaccggt gatgaaggtt ttgcagacct
      541 ctgccttacc acttggctat accgccatta tactattatc aatctataaa ataaagaata
      601 aattatagaa actggggtag ctggattcga accaacgcat gagggagtca aagtcccttg
      661 ccttaccgct tggctatacc ccaagaataa aaagggcgaa tgatgggaat cgaacccacg
      721 aatgccggag ccacaatccg gtgcgttaac cacttcgcca cattcgccat ggcaggggca
      781 gcaggaattg aacccacact aacggttttg gagaccgctg ttctaccttt aaactatgcc
      841 cctataaaat ggaggagagt ggattcgaac cactgaaccc taaggaacgg atttacagtc
      901 cgtcgcgttt agccacttcg ctactcctcc atggtggcgc gggacagaat cgaactgccg
      961 acacacggag cttcaatccg ttgctctacc aactgagcta ccgcgccata ttttaaaatt
     1021 attaattgaa taacaagaac gacggttccg acgggaatcg aacccgcgat ctcctgcgtg
     1081 acaggcaggc atgttaaccc ctacaccacg gaaccagttc attatggagg ttaacgggat
     1141 cgaaccgctg accctctgct tgtaaggcag atgctctccc agctgagcta aacctccaac
     1201 attcaattaa aatgacccgt acgggattcg aacccgtgtt accgccgtga aagggcggtg
     1261 tcttaaccgc ttgaccaacg ggccaggtaa atttgctacg gagagtaagg gattcgaacc
     1321 cttgagacag tttggcacca tctacatgat ttccaatcat gctccttcgg cctctcggac
     1381 aactctccag agtgaaagaa gctcaatact ctttctcaaa atgag
//
LOCUS       DBBGSZ010000112         1374 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.122, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000112 DBBGSZ010000000
VERSION     DBBGSZ010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1374
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.122"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            39..1340
                     /locus_tag="ACIZE5_002836"
     CDS             39..1340
                     /locus_tag="ACIZE5_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGC6109906.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          448 a          275 c          253 g          398 t
ORIGIN      
        1 aattgaatca ccacaacaca atcaaaggag cgttctgtat gcctgatctt catcatatca
       61 aactactact tggaatcaaa gataaaaaca ttttcatcac aaatgtggaa tcgaagagca
      121 ttaagaatat caagagtctt gttgtttctg cgacgttaag taaagaaatt cgtcgctgtc
      181 ctttgtgtaa acagatgaat catgaaggca tgatcgttaa gaacggaaag aaaaaatcgc
      241 tcattcaact taataaatgt gcgaaccaac tgacttatct tgctttagcg aaacaacgct
      301 accactgtcg tggctgccac acctatttta cggcgaatac ctacattgtc gatagaaact
      361 gctttatcgc taaacaagtg cgctataaaa ttttagaaga gctaactgaa aaacaagcaa
      421 tgacgacaat tgctaagcat tgcggcgttt cttggtcgac cgtttctcgg acactcgctt
      481 ctctgatccc catgacaaaa gtaaaaagaa attggttacc gcgttgttta ttaatggatg
      541 aatttcgttc actgaaaaat caagtcggtc cctactcctt ttcttgtatg gatggcgata
      601 ctggaaaatt actggatatt cttccttcac ggaagaaaaa ggctctcgtt tcttatttta
      661 tgcaatttga acgacgcgca cgattgaagg taaaggtcat cgtgacggac atgaatgttt
      721 cttatgcctc tctgataaag gaatgttttc caaaggcaaa actcgttgtg gatcgttttc
      781 acattgtcaa acatctcatt cgtaaatttg aggatattcg cgtacgaatc atgaaaagct
      841 ttgatcgaaa cgatccaaca caagccaaat attatcgaca attaaaggcg ttgtctcggc
      901 ttctgatcaa acgacaggac aagcttgttt atgacaaatg gaccaaatgg cgcaattttg
      961 gttgggcgta tctcaccgaa agtgaagtgg tggatcgtct gctttcgatc tctgacgaat
     1021 tacgaatcgc ctatttttac tatcaagaaa ttcttcaagc gtttcacgac aaagaggcgg
     1081 acactttctt taaacttgta agaacgatgc ccaattccgt tccaaaagaa ctgcattcta
     1141 taaaaaaagc ttttataaac tatgaatccg gcattcgttt agccctcgaa ttgccttatt
     1201 caaatgccaa aatagaaaat ctgcataccc acatcaaagc attgaaacga gtcgcttatg
     1261 gctttcgaag ctttcggaaa atgaagacca gaattttctt actaaataat ctgattacct
     1321 atgaatcaaa aaacatctaa agtagaaaag gaattctacc ttagatgttc ttat
//
LOCUS       DBBGSZ010000113         1362 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.123, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000113 DBBGSZ010000000
VERSION     DBBGSZ010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.123"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            180..587
                     /locus_tag="ACIZE5_002837"
     CDS             180..587
                     /locus_tag="ACIZE5_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109907.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            601..1002
                     /locus_tag="ACIZE5_002838"
     CDS             601..1002
                     /locus_tag="ACIZE5_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109908.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1004..>1362
                     /locus_tag="ACIZE5_002839"
     CDS             1004..>1362
                     /locus_tag="ACIZE5_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109909.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKII"
BASE COUNT          526 a          170 c          237 g          429 t
ORIGIN      
        1 atagaggcac ttttactact gattaaatgt cagatatgct tacaaatata cttataaata
       61 tgcttacaaa attagctaat atttccgttg acaaagcttt gttactattg ttaaactaaa
      121 ttgactagca aaagtgaaac ataaatttat taaataaatg taaaaattag gagaaatcaa
      181 tgtcttatag agtacaatta ataatttcag aagatgtaga aagtcagcaa tttggcacta
      241 atgttattaa taaagtaatt aatccagctc tttctattaa tgcgccttta attcctactg
      301 ctttatcatt ttctgtaaca gctgtggtgt ctgagataga ggatacagaa aagataaaaa
      361 tagtagaaat tgaagtttta aacaagaatg aaaaacaaat tttttctacg ggtgaagtat
      421 cggtaagctt gcctcctcaa gttaacgata taaactttaa tataaacgcc agaaatgtct
      481 tggttgaaga agcaggagag cattatgctg ttgttaaatt taatggaact gagattggaa
      541 ggcaaatctt tgatatcaag gtcaacaaac cagtggaaaa aaattaagga gacgatacgg
      601 atgcttgata tagtaccatc aaatacacat cggagtggta gcttaataaa ttttgctgcg
      661 atttttgctt gcgcatcggt aattctagca tctccagttg ttgtggatgc aagttctact
      721 ccgaaaacta aaaatgataa tcaacttgta attactacaa aaaatgagat taacacaatt
      781 tcaagtaatg atggcaaaat ttttgatgtg ataaatacgg ttttaaaaag aaaagctgaa
      841 atcaatataa aatatgatga agatttaaac ttgtatttct ttgttatcaa aacaacatct
      901 gaattgtttt cctcagatta cgatgttttg gatactctcg ataatgtatt atctgactat
      961 aaatatatgg ggaaatctgt agtagcaact ttgggggaat aaaatgtttg actttaatga
     1021 atatttatct atttccaaac aaattgaatc agatgataaa tataattcta aagaatctta
     1081 tagaagaact gctgtttcaa gagcatacta cagtgctttt aaaaaatctg atgagtattt
     1141 gaaagaaaat tatgatatta tttataatgg aagtagcgga aaaggaagcc accaaaccgt
     1201 ttggaatttg ttttcaacag ttaaggaatt gaatacctta ggaatacata atagtgggta
     1261 tagaatgtta gagaaaagaa aatgtgctga ctatattcct aatgaaacca ttacgaaaac
     1321 agatatggcg ctgatgaatc gagaagcaga aaaaataata aa
//
LOCUS       DBBGSZ010000114         1355 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.124, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000114 DBBGSZ010000000
VERSION     DBBGSZ010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.124"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..1355
                     /locus_tag="ACIZE5_002840"
     rRNA            <1..1355
                     /locus_tag="ACIZE5_002840"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          362 a          295 c          415 g          283 t
ORIGIN      
        1 caagctgtga tggggaggga aataatagta ccgaagttcc tgatgtcaca ctgccgagaa
       61 aagcttctag tgagaaaaca gcggcccgta ccgcaaaccg acacaggtag tcgaggagag
      121 aatcctaagg tgagcgagag aactctcgtt aaggaactcg gcaaaatgac cccgtaactt
      181 cgggagaagg ggtgctgatc atacgatcag ccgcagtgaa taggcccaag cgactgttta
      241 tcaaaaacac aggtctctgc aaaatcgtaa gatgaagtat aggggctgac gcctgcccgg
      301 tgctggaagg ttaagaggag tgcttagcgc aagcgaaggt acgaattgaa gccccagtaa
      361 acggcggccg taactataac ggtcctaagg tagcgaaatt ccttgtcggg taagttccga
      421 cccgcacgaa aggcgtaacg atttgggcac tgtctcaacg agagactcgg tgaaatttta
      481 gtacctgtga agatgcaggt tacccgcgac aggacggaaa gaccccatgg agctttactg
      541 tagtttgata ttgagtgtct gtaccgcatg tacaggatag gtaggagccg tagaaatcgg
      601 aacgctagtt tcgatggagg cgctggtggg atactacccc tgcgttatgg ccactctaac
      661 ccgcaccact aatcgtggtg ggagacagtg tcagatgggc agtttgactg gggcggtcgc
      721 ctcctaaaag gtaacggagg cgcccaaagg ttccctcaga atggttggaa atcattcgaa
      781 gagtgtaaag gcagaaggga gcttgactgc gagaccaaca agtcgagcag ggacgaaagt
      841 cgggcttagt gatccggtgg ttccgcatgg aagggccatc gctcaacgga taaaagctac
      901 cctggggata acaggcttat ctcccccaag agtccacatc gacggggagg tttggcacct
      961 cgatgtcggc tcgtcgcatc ctggggctgt agtcggtccc aagggttggg ctgttcgccc
     1021 attaaagcgg cacgcgagct gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc
     1081 gcgggcgttg gaaatttgag aggagctgtc cttagtacga gaggaccggg atggacttac
     1141 cgctggtgta ccagttgttc tgccaagggc attgctgggt agctatgtag ggaagggata
     1201 aacgctgaaa gcatctaagt gtgaagccca cctcaagatg agatttccca tttctttaag
     1261 aaagtaagat ccctgagaga tgatcaggta gataggtcag gagtggaagt acagtgatgt
     1321 atggagcgga ctgatactaa tcgatcgagg actta
//
LOCUS       DBBGSZ010000115         1282 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.125, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000115 DBBGSZ010000000
VERSION     DBBGSZ010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.125"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..549
                     /locus_tag="ACIZE5_002841"
     CDS             <1..549
                     /locus_tag="ACIZE5_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HGC6109910.1"
                     /translation="IEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFR
                     FEGVTGREISLKDESNTTVSDANILANIILDFIFEHHIPFKEGYEILPANQEYYFYKC
                     ITKRVCCICGKTGADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVTNFK
                     NKYQIKGIKLNQETIKKLRIGG"
     gene            552..779
                     /locus_tag="ACIZE5_002842"
     CDS             552..779
                     /locus_tag="ACIZE5_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109911.1"
                     /translation="MINLNAVAFEQTWRTKYKKMSPRDKLFLEIMTFAFIGTQAEQSD
                     ISVEKIKTNRLVNGITETCYQYTIIVVDEEE"
     gene            797..>1282
                     /locus_tag="ACIZE5_002843"
     CDS             797..>1282
                     /locus_tag="ACIZE5_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replisome organizer"
                     /protein_id="HGC6109912.1"
                     /translation="MFAKTIIDSDAFLDMPLSTQALYFHLSMRADDDGFINNPKKIQR
                     MVGCGDDDLKLLMAKRFILVFESGVIVIKHWKIHNYIRNDRYKPTLYQDEKALLADKD
                     NKAYTFAEELSKHDEKLGIPDDNQAVYQMDTQVRLGKDRLGKDSKEIKDLTPSKKSKA
                     KP"
BASE COUNT          469 a          211 c          256 g          346 t
ORIGIN      
        1 attgaaattc gttttattga tcctagacgt ttcacagtac agcaacgaaa cttcatctat
       61 gcactcatag gcgatatttt catcgataca ggcatgccaa cggacttctg gaaggaattc
      121 ttttacttcc gtttcgaagg tgtcacaggg cgcgaaataa gcctcaaaga tgaatcgaat
      181 acgactgtga gtgatgccaa tatcttagca aatatcatct tagattttat ctttgaacat
      241 catattcctt tcaaagaagg ctatgagatt ttaccagcga atcaagaata ttacttctac
      301 aaatgcatca caaaaagagt ctgctgtatc tgtggcaaaa caggagctga tatcgatcac
      361 tttgacaaag cgctaggaag acgaaagcgc aaagaagttg atcattcaga gtacacattt
      421 gcagcactct gtagaattca tcacacggag aaacacaaaa taggtgtgac caatttcaaa
      481 aataagtatc aaatcaaagg gattaagtta aaccaggaga caatcaagaa attaagaatc
      541 gggggctaat gatgattaat ttaaacgcag tagcgtttga acaaacatgg cgcactaagt
      601 ataaaaaaat gagtccaaga gacaaattgt tcttagaaat catgacattt gctttcattg
      661 gtacacaagc tgaacaaagc gatattagtg ttgaaaaaat taagacgaat agattagtta
      721 atggaattac agagacttgt taccagtaca cgattatcgt cgtggatgag gaggaataat
      781 tttggcagaa agaagaatgt tcgcaaagac aattattgat tctgatgcat tcctagatat
      841 gcctttatcg acacaggcat tatatttcca tctatcaatg cgcgcagatg atgatggatt
      901 tattaataat cccaaaaaaa tacaacgtat ggttggttgt ggtgatgatg atttaaaact
      961 gcttatggca aaaagattca tcttagtttt cgagagcggt gtgatcgtca ttaagcattg
     1021 gaaaatacac aactatattc gtaatgatcg ttacaaaccc acgttatatc aggatgaaaa
     1081 agctttacta gcagacaaag ataacaaagc ttatacattt gcagaagagc tttctaaaca
     1141 tgatgaaaaa cttggtatac cagatgacaa ccaagcggta taccaaatgg atacacaggt
     1201 taggttaggt aaggataggt taggtaagga tagtaaagag ataaaagatt taacgccttc
     1261 gaaaaaatcg aaggctaagc cc
//
LOCUS       DBBGSZ010000116         1248 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.126, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000116 DBBGSZ010000000
VERSION     DBBGSZ010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1248
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.126"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            200..743
                     /locus_tag="ACIZE5_002844"
                     /pseudo
     CDS             200..743
                     /locus_tag="ACIZE5_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            899..>1248
                     /locus_tag="ACIZE5_002845"
     CDS             899..>1248
                     /locus_tag="ACIZE5_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HGC6109913.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          516 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa aatacatcag
      721 aagaaaaaaa tctaaaatta taaaatgtga tactcatact aaaataggag tttcaagtga
      781 tggaaaatac gattgctatt taagcacaaa tagcggagct gaaagtaatc ttctggatga
      841 attaaaaaga actgagattc aaattataga taaaaaagaa cgtcctaaaa atggttttgt
      901 gctatcagaa aaaactgatt tagaaaatac agaagcattt aacaaagaat cggttaaaga
      961 tttacgtaaa ctaccaacaa aggacataaa tggcaaggat tttacaagta aagattttga
     1021 gaagtatgat cttactatgg taaatgtatt tgcaacttgg tgtacagctt gtgtaaagga
     1081 aattcctgat ttggttgagg ttcagaatga aatgaaaagc aagggtgtaa atatcgttgg
     1141 agttgttaca gatcctgttg atgataacgg tgaaaacaag gaagcaattg aaaagtcaaa
     1201 gttaatacat gaaaagacaa aggcttcata tcctttctta atgccaga
//
LOCUS       DBBGSZ010000117         1194 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.127, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000117 DBBGSZ010000000
VERSION     DBBGSZ010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1194
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.127"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..1076
                     /locus_tag="ACIZE5_002846"
     CDS             <1..1076
                     /locus_tag="ACIZE5_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HGC6109914.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          210 g          332 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tctt
//
LOCUS       DBBGSZ010000118         1188 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.128, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000118 DBBGSZ010000000
VERSION     DBBGSZ010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.128"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            141..398
                     /locus_tag="ACIZE5_002847"
     CDS             141..398
                     /locus_tag="ACIZE5_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109915.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..1061)
                     /locus_tag="ACIZE5_002848"
     CDS             complement(630..1061)
                     /locus_tag="ACIZE5_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HGC6109916.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          453 a          151 c          148 g          436 t
ORIGIN      
        1 ttctgtccac gttcatttta ctccaaagtt ttcctcattt caaaagaaaa tcacagaata
       61 cacgaagaag cgtttctatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaatt tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 ataaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaataaat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatacc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga atcaatagat
     1021 tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa atcattaaca
     1081 aaaatattat aataggattt aagtaagttc taactaatca catataaaaa taaaaaaaca
     1141 tttgtatttt atcaaagttt tattatactt gtcaatttgt gtacatcc
//
LOCUS       DBBGSZ010000119         1147 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.129, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000119 DBBGSZ010000000
VERSION     DBBGSZ010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1147
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.129"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..>1147
                     /locus_tag="ACIZE5_002849"
     CDS             <1..>1147
                     /locus_tag="ACIZE5_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGC6109917.1"
                     /translation="ENCLTKEKYKGQICLIYKGTLLYKPEECSHCLCVVPSRIIRWGT
                     TTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADTSVAEKHCFISQKVRWSVIARL
                     KENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQTLPKVLCFDEFKSVRSVASAMS
                     FIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREAVQLIVIDMYAPYVSLVKKLFP
                     NAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHSQRGLGKKLKRYWKLLQKEEAK
                     LNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQLYQDILYAVKKRDQSLFEDCL
                     TRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGPLECLNNHIKVL"
BASE COUNT          351 a          227 c          231 g          338 t
ORIGIN      
        1 gaaaattgtt taactaaaga aaaatacaaa gggcaaattt gcttgattta caaaggaact
       61 cttctgtaca agccagaaga gtgttcccat tgtctttgtg tcgtcccctc taggatcatt
      121 cgttggggga cgacaaccgt tcggttgtta ctgaatgatg tgtctgagta tcgcacttat
      181 ctggagctga agaaacaacg atttaaatgt aagtcttgcc aaagaacatt cgtagcggat
      241 acctctgttg ctgaaaaaca ctgtttcatt agtcaaaaag ttcgttggtc tgtcattgct
      301 cgcttaaaag agaatacttc catgacggaa atcgctcgtc agaaaaatat ttccacttct
      361 tcggtctatc gtgtcatgaa gcgattctac cgcccattga atcctttcaa acagactttg
      421 ccaaaggtct tatgctttga tgaattcaaa tcggttcgaa gtgttgccag tgcaatgagt
      481 tttatcatga tggacggaca aagccatgca ttattggata ttgtcgaaaa tcgacgcttg
      541 ccttatttag aacgctattt ttctcggttt tcattagcga ctcgtgaagc cgttcaattg
      601 attgttattg atatgtatgc gccttatgtt tcgttggtga aaaagctttt cccgaatgct
      661 cagttgatca tcgatcgttt ccacatcgtc caacatattg gcagaacttt cttgaatcat
      721 cgagtgaaag aaaccacggt acgacttaaa ggaaattccc actctcaacg agggttaggg
      781 aaaaaattga agcgctattg gaaactccta caaaaagaag aagcaaagtt aaactatgaa
      841 aaacgggttt ggcgtgccag ttttaaagat tatttgactg aaagtgagat tgccgatcga
      901 ctgttagctg cttgtcccaa cttacgccaa ggctatcagt tataccaaga cattctttat
      961 gcggtaaaga aaagagatca gtcactattt gaggattgtt taactagaga cattagcggt
     1021 ctgccagaaa cctatacaac cactttacga acgtttaaaa agtttctgcc acagatccaa
     1081 aatgcgcttc actacagcta ttcaaacgga ccattggaat gcttaaacaa ccacatcaaa
     1141 gtattaa
//
LOCUS       DBBGSZ010000120         1069 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.130, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000120 DBBGSZ010000000
VERSION     DBBGSZ010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.130"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            82..>1069
                     /locus_tag="ACIZE5_002850"
     CDS             82..>1069
                     /locus_tag="ACIZE5_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HGC6109918.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPP"
BASE COUNT          361 a          204 c          207 g          297 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccc
//
LOCUS       DBBGSZ010000121         1069 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.131, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000121 DBBGSZ010000000
VERSION     DBBGSZ010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.131"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..919)
                     /locus_tag="ACIZE5_002851"
     CDS             complement(<1..919)
                     /locus_tag="ACIZE5_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGC6109919.1"
                     /translation="MSKRGTIINEWENLTALSNRRLNVQNLNTPLKLQWSIDRITIVG
                     KLKENIYYHTQNDVLILDFEQLMRLNENNGYVKSVGLNGWQIVDKHDENIAYIEILKY
                     QEGQGRIDFNPNKINQFLASSMKNFIHDLFLEPHFSRADIACDIIDVPDEFITQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRMYNKKLEQERKRKIVPKEIETWWRLELQ
                     LRRGKATDWHEMVHESLDSFASLHFLPIDTTPTDRIMLAGLMSDQNFWSLLSRNSKYK
                     YRELLKEESQNDELTNHLRETFAESADNLK"
BASE COUNT          344 a          220 c          153 g          352 t
ORIGIN      
        1 gtttcaaatt gtctgccgat tctgcaaacg tttctcgcaa atgattcgtc aattcatcat
       61 tttgactttc ttctttcagc aattcccgat atttatattt tgaattcctc gacaaaagag
      121 accagaaatt ttgatcagac attaaaccag cgagcattat tctatctgta ggtgttgtat
      181 caatcggcaa aaaatgcagg ctcgcaaaac tatccaaact ttcgtgaacc atttcatgcc
      241 aatcagtggc tttcccacgt cgcaactgca attctaaacg ccaccaagtt tcgatttctt
      301 tcggaacaat tttccgtttt ctttcttgtt ctaatttttt gttatacatc cgaatttgac
      361 gttcactagc acgactgccc caataagcag tttctaactt gccagaccga ccataaattg
      421 gtttaaacga tacaggatca accacccgat attgggtaat aaactcatca ggcacatcga
      481 taatatcgca agcaatatcc gcacgtgaaa aatgcggctc caaaaataaa tcatggataa
      541 aattcttcat agagctagct aaaaactgat taattttatt cggattaaag tcaattcgcc
      601 cttgaccttc ttgatatttc aaaatttcaa tgtaagcaat attctcatca tgcttatcca
      661 caatttgcca accatttaga ccaacagatt taacataacc attattttca ttcagtcgca
      721 ttaactgttc aaagtctaaa atcaatacat cattttgagt atgataataa atattttctt
      781 tcagttttcc aacaatggta attcggtcaa ttgaccactg taattttagg ggggtgttca
      841 aattttgaac atttaaccgc ctgttagata gggctgttaa attttcccac tcatttatga
      901 tcgtgccacg tttactcaaa ttttattcct cctcaaagaa aaagagactt ctggaaagaa
      961 ttttcaaaag ttcacgtaac tcttaaaaat tcattaccaa aaaatctcta gtcttgaaga
     1021 aatctaaaaa tattcgtata atgattaaga agttacggag ctagtgtga
//
LOCUS       DBBGSZ010000122         1065 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.132, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000122 DBBGSZ010000000
VERSION     DBBGSZ010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1065
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.132"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            147..>1065
                     /locus_tag="ACIZE5_002852"
     CDS             147..>1065
                     /locus_tag="ACIZE5_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGC6109920.1"
                     /translation="MSKKGIIVNEWEKLNRISNRRLSVDDKVHPLKLSWSIDRITIVG
                     KLNDTIAYWTQNGVVFVDFEQLMRLNENQGYLKSVGTNGWQLFDQYGEDIAYIEMLKF
                     HPDKGRIDFNPNKIGEFLKGSMKQFIHDLFLDAHFSRADIACDILGVPDDFITQYRIV
                     DPVSFKPIYGRSGKLETAYWGSRASERQVRMYNKKLEQERKKQIVPKEIETWWRIEMQ
                     LRRGKATDWHAMVRESLDSFASPHYLPGDVKPVDRIMIKGLNQDHSEWAYISRNLKYR
                     LRKLLKEESQNDELTNHLRETFKESANDLK"
BASE COUNT          345 a          162 c          242 g          316 t
ORIGIN      
        1 ttcacctagt tccgtaactc aagttcatta tacgaatatt tttaggtttc ttcaagctag
       61 agatttttgg atgtggattt ttagagttac gtgaactctg gaaattcttt ccaagaatct
      121 cttttttcgt tgaggaggag ctatttttga gtaaaaaagg cataatcgta aatgagtggg
      181 aaaaacttaa ccgtatttct aacaggcggt taagtgttga cgataaggta caccccctaa
      241 aattaagttg gtcaatcgat cgaattacaa tcgtcggaaa actgaatgat accatagctt
      301 attggacgca aaatggagtt gtgtttgtcg attttgagca attaatgcgt ttgaatgaaa
      361 atcaagggta tttgaagtcg gttggtacaa atggttggca attatttgac caatatggag
      421 aagatatcgc ctatatcgaa atgttaaaat ttcaccctga caaaggtcgt attgatttta
      481 atccaaataa aattggcgag tttttaaagg ggtcgatgaa acaattcatt catgatttgt
      541 ttctggatgc gcatttctca cgtgcagata ttgcttgcga tattctcggt gttcctgatg
      601 attttattac ccagtatcga atcgttgacc ctgtgtcttt taagccaatt tatggccgtt
      661 ctggcaaatt agaaacagcg tactggggta gtcgtgccag cgagcgacaa gtgcggatgt
      721 acaacaaaaa gcttgaacag gaacgaaaaa aacagattgt accaaaagaa atcgaaacat
      781 ggtggcgtat agaaatgcag ctaagacgtg gcaaagcaac agattggcat gcgatggttc
      841 gggaaagttt agatagcttt gcaagtcctc attacttgcc tggagatgta aaacctgttg
      901 atagaattat gataaaaggg ctgaatcaag atcattcaga gtgggcgtat attagcagaa
      961 atttgaaata tagattgcgc aaattgttga aagaagaaag ccaaaacgat gagttgacga
     1021 atcatttacg agagacgttt aaggaatctg caaacgactt gaaaa
//
LOCUS       DBBGSZ010000123         1061 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.133, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000123 DBBGSZ010000000
VERSION     DBBGSZ010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1061
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.133"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(36..>1061)
                     /locus_tag="ACIZE5_002853"
     CDS             complement(36..>1061)
                     /locus_tag="ACIZE5_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HGC6109921.1"
                     /translation="LTGNPKNIRLFLYNLFNSTEISFVELYTLPIIIKTEKMLKDLKQ
                     YYPLSAYEKKKLFHFLAINLLAEQADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFI
                     NKTLSWLYLHDKLDQKYLRKNEDETIEWLNERFIESFENQFNLLREETSQLIRRELTK
                     IHFKLLHYTINKADEFPLDVSFFRENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFS
                     YLLLLINHIPIQLISEPVKIIIDFSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPD
                     VIITNRNNLYEESASQVVVWLDPPRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPE
                     EIIDRIE"
BASE COUNT          346 a          177 c          160 g          378 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgtca a
//
LOCUS       DBBGSZ010000124         1001 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.134, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000124 DBBGSZ010000000
VERSION     DBBGSZ010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.134"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(81..635)
                     /locus_tag="ACIZE5_002854"
     CDS             complement(81..635)
                     /locus_tag="ACIZE5_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6109922.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADVAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
BASE COUNT          324 a          186 c          107 g          384 t
ORIGIN      
        1 cttccgaaaa ttcagttatc ttcattaatc tcaccttcta agttttcatt atacacaaaa
       61 aatatatcct aatatctcaa ttagcctccc aatttaaaac cacgtaacga tgcccctatt
      121 tcatcttcag ttataccaat gtaccttttt gtaattgctt gcgagctatg attaaaaata
      181 aacattaagg tagcaatgtc tctagttttc ttgtagtagt gatacccaaa agtttttctt
      241 aatgtatgtg ttcctatatc atctcttcct aatttttctg ctacatctgc atatatctga
      301 tagacacgat cccttgttat atgtcgacct tgttgccgac ttggaaataa ccaatcattt
      361 tcttctttac cttcagtata taataaaatc tcttctctca aattatctat aaaaatcggt
      421 tttcgcttac ctgttttatg ttcaacaata ataggcttac ttttacctcg tatgtctcca
      481 acttttaatc ctataatatc tgacatacgt aacccattat tgattccaaa caaaaataaa
      541 aaactatctc tttctggatt acttgttctt cttagccaaa actgaaaatc ttgtatctct
      601 tcatttgtcc ttaacggttg tacattatag ctcactattg tttcccttct taaaaatatt
      661 ctgagttcat gattatatat atattttacc ataatcatga acttatatat atactctgtt
      721 aaaagtgaag aaaatcaagg ggtttagttt atgattttat atcatttcag taactcagaa
      781 tattccgact tttttgtaca aaaaaattaa ccttacttat atgaagattc taagctctta
      841 tttaaatttt agacgggcag ttatccgtag aagttcttag aatagctaat ttacataatt
      901 aaattatatg aaatttaagt ttgaacaata tactaagaac tccccttact ataaagtgaa
      961 ataaattagc atatgaataa ccgtgctacc aaacttttca t
//
LOCUS       DBBGSZ010000125         1000 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.135, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000125 DBBGSZ010000000
VERSION     DBBGSZ010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.135"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            369..1000
                     /locus_tag="ACIZE5_002855"
                     /pseudo
     CDS             369..1000
                     /locus_tag="ACIZE5_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          181 c          183 g          294 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata
      301 taggctctat aatttatggg actgatgaat caaaattgat tcttcagtcc cattgttatt
      361 ttaggtatat gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa
      421 ggaccctgcc aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata
      481 aaatgagctt tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac
      541 gaaaattgtc tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat
      601 atttagtgac agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg
      661 cgaaagtcgt cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt
      721 ttcgtgtaca agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag
      781 tgaaaaagaa ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca
      841 aaacatggcg cagttttcgt gcacctaaat acccgctact cactgaagca atgatgattg
      901 atcgattgct ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga
      961 ccgaagcctt tagagacaag gaatcagact tattttttac
//
LOCUS       DBBGSZ010000126          974 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.136, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000126 DBBGSZ010000000
VERSION     DBBGSZ010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..974
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.136"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..555
                     /locus_tag="ACIZE5_002856"
     CDS             <1..555
                     /locus_tag="ACIZE5_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HGC6109923.1"
                     /translation="IEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFR
                     FEGVTGRKISLKDESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKC
                     ITKRVCCICGKTGADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFK
                     NKYQIKGIKLNQKTIKKLNIGGEK"
     gene            552..>974
                     /locus_tag="ACIZE5_002857"
     CDS             552..>974
                     /locus_tag="ACIZE5_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6109924.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKP"
BASE COUNT          368 a          169 c          186 g          251 t
ORIGIN      
        1 attgaaattc gttttattga tcctagacgt ttcaccgtac agcaacgaaa cttcatctat
       61 gcgctgatag gcgatatttt tatcgataca ggcatgccaa cggacttctg gaaggaattc
      121 ttctactttc gttttgaagg tgtcacaggg cgcaaaataa gcctgaaaga cgaatcgaat
      181 acaactgtga gtgatgccaa tgtcttagca aatatcatct tagatttcat ctttgaacat
      241 catattcctt tcaaagaagg ctatgagatt ttacctgcga atcaagaata ttacttctac
      301 aaatgcatca caaaaagagt ctgctgcatc tgtggcaaaa caggagctga catcgatcac
      361 tttgacaaag cgctaggaag acgaaagcgc aaagaagttg atcatgcaga gtacacattt
      421 gcagcactct gcagaatcca tcacacagag aagcacaaaa taggtgtgat taatttcaaa
      481 aataaatatc aaatcaaagg gatcaaatta aaccagaaaa caatcaaaaa gttaaatatt
      541 ggaggggaaa aatgacagaa catcgaagtt attatgcgat tataccagcc aacgtaaggt
      601 acgacaaaag acttaaacca aatactaagt tgttatacgg agagataacg gccttgtgta
      661 atgaaagagg cttttgttgg gcaggcaatg agtactttgc agatttatat ggtgtgaata
      721 aagagaccat atcgcgatgg gtaagtgatt tgattaagtt tggatacttg aatcgggaaa
      781 tcatttacaa agagggtacc aatcaaataa tcaataggta cctacgaatt aatcaatacc
      841 ctattgacga aaaacgcaat acccctattg acgaaaaagt caaagataat aatacatcta
      901 ttaataatac atttaataat acaaaagaat atataagaga gttaccgcct tcgaaaaaat
      961 cgaaggctaa gccc
//
LOCUS       DBBGSZ010000127          952 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.137, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000127 DBBGSZ010000000
VERSION     DBBGSZ010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.137"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..>952
                     /locus_tag="ACIZE5_002858"
     CDS             <1..>952
                     /locus_tag="ACIZE5_002858"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGC6109925.1"
                     /translation="EPGDFIMSGAGTIGRISRVPKQIKPGVFNQALIRLRINKEITDS
                     EYFIQFIRADFMQRKLTGANPGSAITNLVPMSEVKKWIVQFPILEEQKKIGNFFKQLD
                     DTIALQQRKLDLLKETKKGFLQKMFPKNGAKVPEIRFPGFTEDWEQRKFKEFSKKTGK
                     KNTKDLDFPAYSVSNKAGLISQTEQFDGSRLDDLEKTNYKFVEPNEFAYNPARVNVGS
                     IAFNNLGMTVIVSSLYVVVKMSEDLDNEFILQFIKSPTFIKEVKRNTEGSVREYLFYE
                     NFANIKFPFTRNKEEQQKIGAFFKQLDDTIALHQRKLDLL"
BASE COUNT          360 a          155 c          182 g          255 t
ORIGIN      
        1 tagaaccagg cgattttatc atgagtggcg ctggaacaat tgggagaatt tcaagagtac
       61 caaagcaaat aaaaccgggt gtattcaatc aggctttgat tagacttaga ataaataaag
      121 aaatcacaga ttcagaatat tttattcaat ttattcgtgc agattttatg caaagaaaac
      181 tcacaggagc taatccaggt tcagcaatta caaatctcgt accaatgtca gaagtgaaaa
      241 aatggatagt acaatttcca atattagaag aacaaaagaa aattgggaac ttcttcaaac
      301 aactggacga cactatcgct cttcaacaac gtaagctaga tttattaaag gaaacgaaaa
      361 aaggattctt acaaaaaatg ttccctaaaa acggagcaaa agtgccagaa attcggtttc
      421 ctggatttac ggaagattgg gaacagcgta agttcaaaga gtttagtaag aagactggaa
      481 aaaagaacac gaaagattta gacttccctg cctattcggt aagtaataaa gcaggtttaa
      541 tttctcaaac agaacagttt gatggtagta ggttggatga tttagaaaaa acaaattata
      601 aattcgttga accaaatgaa ttcgcctata atccagcaag agtaaacgta ggatcaattg
      661 catttaacaa tcttggtatg acggtcattg ttagctctct ttatgtagtt gtgaaaatga
      721 gcgaggactt agataatgag ttcatacttc agtttatcaa gtcaccaaca tttatcaaag
      781 aggtcaagcg caacactgaa ggaagcgtac gagaatactt attctatgag aatttcgcta
      841 atatcaagtt tccttttact aggaataaag aggaacaaca aaaaatcggc gctttcttca
      901 aacaactcga cgacacgatc gctcttcatc aacgtaagtt agatttgctg aa
//
LOCUS       DBBGSZ010000128          943 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.138, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000128 DBBGSZ010000000
VERSION     DBBGSZ010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.138"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..>943
                     /locus_tag="ACIZE5_002859"
     rRNA            <1..>943
                     /locus_tag="ACIZE5_002859"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          293 a          187 c          274 g          189 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact agg
//
LOCUS       DBBGSZ010000129          940 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.139, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000129 DBBGSZ010000000
VERSION     DBBGSZ010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..940
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.139"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..459
                     /locus_tag="ACIZE5_002860"
     CDS             <1..459
                     /locus_tag="ACIZE5_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109926.1"
                     /translation="AKYLKTHVEAIDGKEALVQTDGDQAIAGHKNFSGSVTINNKRVL
                     TTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGNDSVILTVPEGYR
                     TPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVITYSI"
     gene            473..904
                     /locus_tag="ACIZE5_002861"
     CDS             473..904
                     /locus_tag="ACIZE5_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109927.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
BASE COUNT          358 a          135 c          197 g          250 t
ORIGIN      
        1 gctaaatact taaaaacgca tgtagaagct attgatggta aagaagcatt ggtgcagaca
       61 gatggagacc aagccattgc aggacataag aatttttcag gttctgtaac aatcaataat
      121 aaacgtgttt tgacgactga tgataacaga tatgaagtgg taaatctggt tgtcactaac
      181 ggtaatacag ggacagcaaa gctttatcgt gaaggaaaaa cagtttctat atattttgtg
      241 gctttaaacg gaaaaagtag tggcgggaat gattcggtta ttttaactgt tccagaaggc
      301 tatcggacac caattagttt tgaacaactg gttgggtcaa tagaccgttc tactttgaac
      361 agtgctcaac tatctattgg cgcagacgga gccattaaat ggagaagaaa ttcaagttat
      421 ggatcagctt attcatttgt tatcacttat tcaatttaag ggaggaaatc taatgaaagt
      481 agtttacaaa tcaatcaagc cttacggatt cgagcaaatc attttgaaca atcaagaaaa
      541 tatccctgaa aactgtacag agattaaacc accagttcct aactggagac caagatttga
      601 ttttgataaa aaacagtggg ttgagttagc tactgaagaa gagaaaaaag ggaatgctgt
      661 tgatagcgta gatgaattgg ctaatattaa ggcattatac gaaacgctga aggcagaaaa
      721 tgatgaattg aaacagctaa attctaaagc aatgctaaac aatgtagcaa tcaagcaaga
      781 aaatgtctta ttgaaagaaa agtcagaaag tttagcgcag ttgaattcaa aaacgatgct
      841 tgcttctgta caaaatacca aggaaatcga agaaatcaaa aaacaattac aaggtgggaa
      901 gtaacatgta ttcatatgaa gatatcaaac taatgtatga
//
LOCUS       DBBGSZ010000130          827 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.140, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000130 DBBGSZ010000000
VERSION     DBBGSZ010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..827
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.140"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..>827
                     /locus_tag="ACIZE5_002862"
     rRNA            <1..>827
                     /locus_tag="ACIZE5_002862"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          205 a          201 c          247 g          174 t
ORIGIN      
        1 gaaagccccc ggctcaaccg gggagggtca ttggaaactg ggagacttga gtgcagaaga
       61 ggagagtgga attccatgtg tagcggtgaa atgcgtagat atatggagga acaccagtgg
      121 cgaaggcggc tctctggtct gtaactgacg ctgaggctcg aaagcgtggg gagcaaacag
      181 gattagatac cctggtagtc cacgccgtaa acgatgagtg ctaagtgttg gagggtttcc
      241 gcccttcagt gctgcagcta acgcattaag cactccgcct ggggagtacg accgcaaggt
      301 tgaaactcaa aggaattgac gggggcccgc acaagcggtg gagcatgtgg tttaattcga
      361 agcaacgcga agaaccttac caggtcttga catcctttga ccactctaga gatagagctt
      421 ccccttcggg ggcaaagtga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg
      481 ttgggttaag tcccgcaacg agcgcaaccc ttattgttag ttgccatcat tcagttgggc
      541 actctagcaa gactgccggt gacaaaccgg aggaaggtgg ggatgacgtc aaatcatcat
      601 gccccttatg acctgggcta cacacgtgct acaatgggaa gtacaacgag ttgcgaagtc
      661 gcgaggctaa gctaatctct taaagcttct ctcagttcgg attgcaggct gcaactcgcc
      721 tgcatgaagc cggaatcgct agtaatcgcg gatcagcacg ccgcggtgaa tacgttcccg
      781 ggccttgtac acaccgcccg tcacaccacg agagtttgta acacccg
//
LOCUS       DBBGSZ010000131          800 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.141, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000131 DBBGSZ010000000
VERSION     DBBGSZ010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..800
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.141"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(333..446)
                     /locus_tag="ACIZE5_002863"
                     /pseudo
     CDS             complement(333..446)
                     /locus_tag="ACIZE5_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
BASE COUNT          287 a          125 c          127 g          261 t
ORIGIN      
        1 tctttttcgt tgctttgctc ataaaaatct gcatattcat cactaatatt ttttctaata
       61 aattcttcca tcataaagat cacctcgaaa agagtatacg aacaaacgtt ctttttgtaa
      121 aggtggaatt tattatacta aataaatagg tgaacaagta cttgtgccaa attatgtgcc
      181 aaaaaaaatc gaatttaata aaacacaaac aaaaagaaat cctattatga taacatttct
      241 tataataaca aacacaacag aagacgtgta atagttagtc aggaacgtac aaataacccc
      301 tgtatccttt gcggtacagg gggttatttt gtataagtag acattgtagt ttctaaactg
      361 ctatgtccta aacgtttcga tacgctaagt atatttactc cttgataaag taaaatagat
      421 gcatgcgtat gtcttagtcc atcaataaac agtcgaagag aaaataggga aaaattgatt
      481 actaaagaaa aacttactag gtcgacggtg tagttgattt tcatacttca atagattcga
      541 attaaacgat ttcgattggc ttataccagt cctatccaac gaaagatata tcgttcttaa
      601 ctctagcggt ataacttgaa gctttacgta aagccaatgg gaatgaactg gagatgactt
      661 tttattattt ttagtaatag ctgatgggtt aatacttaca actttccttt tcaaagtacc
      721 atataaaaaa acggtggggt tgtttagcga aataaaggat ctaagccaat agcttagatc
      781 ctttattcta tgctttatat
//
LOCUS       DBBGSZ010000132          771 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.142, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000132 DBBGSZ010000000
VERSION     DBBGSZ010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.142"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..660
                     /locus_tag="ACIZE5_002864"
     CDS             <1..660
                     /locus_tag="ACIZE5_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HGC6109928.1"
                     /translation="YISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFT
                     SKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNK
                     LSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKV
                     DKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGL
                     A"
BASE COUNT          285 a          118 c          143 g          225 t
ORIGIN      
        1 tatatttctt tgttgtgtaa agaagaaatt atcgaattac ctaaaactaa ttccacaatt
       61 ggtattgact taggtattat ggactttgcg attctttctg atggacaaaa aattgataat
      121 aataaattca cgtccaaaat ggaaaagaaa ctaaagcgtg aacaacgcaa attgtctagg
      181 cgtgctttat tggctaaaaa taaaggtacc aatctatttg aagctaaaaa ttatcaaaaa
      241 caaaaacgca aagtagctag attgcatgaa aaagtaatga atcaacgtac tgattttctg
      301 aataagttga gtacagaaat gatcaaaaat cacgatatta tctgtattga agacttaaac
      361 acaaaaggta tgttgcgaaa tcataaatta gctaaaagta tttctgatgt ttcttggtca
      421 aagtttgtga ctaaattaca atacaaggct gactggtatg gacgaaaaat catcaaagta
      481 gataaatggt ttccgtctag tcagatttgt tcagagtgcg gacataaaga tggcaagaaa
      541 tctcttgaaa ttcgagaatg gacttgtcct gtttgtcata ctcatcatga tcgtgatatc
      601 aatgctagta tcaatattct gaccgaaggt ctaagactac attctatggg attggcttag
      661 atccaatcat caagaaccgt aggaactacg gggatagctt ggtaaataag agacaccgct
      721 gttagtaaag aaatacgcta tcaagtatgc tctattccca agaagctccc a
//
LOCUS       DBBGSZ010000133          721 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.143, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000133 DBBGSZ010000000
VERSION     DBBGSZ010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..721
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.143"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(109..>721)
                     /locus_tag="ACIZE5_002865"
     CDS             complement(109..>721)
                     /locus_tag="ACIZE5_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC6109929.1"
                     /translation="GEFNVLHLPMQGKRKPNGYKEKRGKQAFKRNISERKKDYVVFEE
                     EFGHLEGDTIVGIHHKSAIITLVERLSKAIIALKPEGRKAVDIENSINEWLQSVPKNL
                     FKSITFDCGKEFSNWKSISNTNDIDIYFANPGTPSQRGLNEHSNGLLRKNGLPKEMDF
                     NQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA"
BASE COUNT          209 a          118 c          122 g          272 t
ORIGIN      
        1 atcttattat ctttagtgat ataatgaaat atctacacga caaaattatg atcttgcgta
       61 aagttataaa atattaataa aaatatttta ttaatattat ttgtcaaatt aagcgagaca
      121 aaactttcca tttacgtaac tcaaaaaaac ttctaatggt gtttggtaat ttagtgattt
      181 tctagggata tggtttcttt tggacgcaac ggatgagatg aatccttgat tgacttggtt
      241 gaagtccatt tcttttggta gtccattttt tcggaggagt ccgtttgaat gttcatttaa
      301 tccccgttgg gaaggcgttc ctgggtttgc gaaataaata tcaatatcat tcgtattact
      361 aatacttttc caattagaga attcttttcc acaatcaaag gtaattgatt tgaaaagatt
      421 tttgggtacg gattgaagcc attcattaat cgaattttca atatcaactg ccttacggcc
      481 ttctggtttc aaggcgataa tggcttttga aagtcgctca acgagtgtga tgatggcact
      541 tttatggtgg atgccgacaa tcgtatcacc ctctaaatgt ccaaattctt cttcgaaaac
      601 gacataatct tttttacgtt cagaaatatt tcttttgaat gcctgttttc cacgtttttc
      661 cttataacca tttggttttc gttttccttg catcggtaaa tgtaaaacat tgaattctcc
      721 c
//
LOCUS       DBBGSZ010000134          708 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.144, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000134 DBBGSZ010000000
VERSION     DBBGSZ010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..708
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.144"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            96..647
                     /gene="raiA"
                     /locus_tag="ACIZE5_002866"
     CDS             96..647
                     /gene="raiA"
                     /locus_tag="ACIZE5_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HGC6109930.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
BASE COUNT          255 a          125 c          148 g          180 t
ORIGIN      
        1 tgcaaataac ctagagttcg atataataga attaagaaga gggaaagagt ggtccttctc
       61 cttcttgatt gtggtagacg aaaggggtaa tttttatgtt tagatataat gtacgcggcg
      121 aaaatatcga agtaactgaa gcgattcgcg actacgttga gaaaaaagta ggcaaactag
      181 aacgctattt cagtgacgca cccgatgcaa cggcgcatgt gaacttaaaa gtttatacag
      241 aaaaaacagc aaaagtggaa gtaacgatcc cattacctta tcttgtatta cgtgccgaag
      301 aaacttctcc agatttatac gcaagtatcg atttggttgt tgacaaattg gaacgccaaa
      361 tccgcaaatt caaaacaaaa attaatcgta aatcccgtga aacgggcatg aatactgcag
      421 atgctgctgc tttattcaat gaagaggacg aaaacgaaaa tgattctgaa ttagatatcg
      481 tacgtacgaa acgcctttca ttgaaaccaa tggatagtga agaagcagtc ttacaaatga
      541 acatgctggg acataacttc tttatttttg aagatgcaga aacaaatggt acaagtatcg
      601 tttaccgccg taaagatgga aaatacggac tgattgaaac agactgatca gccttactta
      661 aataacaacg aaaacttgca gcagctactg acagctgccg caagtttt
//
LOCUS       DBBGSZ010000135          574 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.145, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000135 DBBGSZ010000000
VERSION     DBBGSZ010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..574
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.145"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..572
                     /locus_tag="ACIZE5_002867"
     CDS             <1..572
                     /locus_tag="ACIZE5_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HGC6109931.1"
                     /translation="IRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIK
                     GRKIYLSPILDLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQY
                     QMPQYQKKLKENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLN
                     EYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          248 a           71 c           94 g          161 t
ORIGIN      
        1 aaatccgaat aaagcgatat aaatcttata aaggaacagt aggaaaaatt gccaagaatg
       61 tgttaaaacg aaatttttca gtagatacac ccaataaaaa atgggtgaca gacgtcactg
      121 aattcaagat aaaaggaaga aaaatctatc tatctcctat acttgattta tttaacggag
      181 aaataattag ttatagtata tcaactagtc caacatataa actgattgaa gaaatgcttc
      241 aacaagcaat taaaaaaaag ggaactgagg gttcactgat tctacattca gatcaaggat
      301 ggcagtatca gatgccacaa tatcaaaaaa aattaaaaga gaataacatt attcaaagca
      361 tgtctagaaa aggaaattgc ttagataatt ctgtaataga aaattttttt ggtgtgctta
      421 aatcagagtt tttttatcga gaaaaattcc gatcaattga gatatttcaa agtaaattaa
      481 atgagtatat taggtggtat aataacaaaa ggataaaact aaagttaaat ggactatctc
      541 cagtagaata tcggaaacag tccattaaat agtt
//
LOCUS       DBBGSZ010000136          534 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.146, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000136 DBBGSZ010000000
VERSION     DBBGSZ010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.146"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..>534
                     /locus_tag="ACIZE5_002868"
     CDS             <1..>534
                     /locus_tag="ACIZE5_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage tail tip lysozyme"
                     /protein_id="HGC6109932.1"
                     /translation="DGFKACTDPRQAAYAFERNYERPAATHPERQDYAVNWYNKFKDL
                     KPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSGYLGGCGMGAGTKYGLTHVIGNT
                     SAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINWARGGQVGSWFADGTYGHTGVIR
                     GLANGRMQTYEQNTELG"
BASE COUNT          163 a           80 c          137 g          154 t
ORIGIN      
        1 tgatggattt aaggcctgta ctgatccaag acaagcagca tatgcttttg aacgaaacta
       61 tgaacgtccg gcagcgacac atcctgaacg tcaagattat gcagttaact ggtataacaa
      121 atttaaagat ttaaaaccag gaggagctac tggagaagca ggactaaaac atttagagtc
      181 tttgattgga caacgaattg gcaatggtca gtgttatggc ttgtctgcag aatattcagg
      241 atatctgggt ggttgtggca tgggtgctgg aacaaaatat ggtttaactc atgtgatagg
      301 aaatacttct gcagcatctg atattggtat tgcctatgat tggtctgctg ttggttggaa
      361 agtgattcaa aaccctagat atgatcaatt agtagttggt gcaattatta attgggcaag
      421 aggtggacaa gtgggttcat ggtttgcaga tggaacttat ggacatactg gcgttatccg
      481 aggcttagct aatggtcgta tgcaaactta tgaacaaaac acagagttag gtat
//
LOCUS       DBBGSZ010000137          529 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.147, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000137 DBBGSZ010000000
VERSION     DBBGSZ010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..529
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.147"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            168..362
                     /locus_tag="ACIZE5_002869"
     CDS             168..362
                     /locus_tag="ACIZE5_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109933.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
BASE COUNT          223 a           66 c           86 g          154 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagct
//
LOCUS       DBBGSZ010000138          528 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.148, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000138 DBBGSZ010000000
VERSION     DBBGSZ010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.148"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(5..90)
                     /locus_tag="ACIZE5_002870"
     tRNA            complement(5..90)
                     /locus_tag="ACIZE5_002870"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="ACIZE5_002871"
     tRNA            complement(107..178)
                     /locus_tag="ACIZE5_002871"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="ACIZE5_002872"
     tRNA            complement(190..262)
                     /locus_tag="ACIZE5_002872"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="ACIZE5_002873"
     tRNA            complement(280..361)
                     /locus_tag="ACIZE5_002873"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="ACIZE5_002874"
     tRNA            complement(369..441)
                     /locus_tag="ACIZE5_002874"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="ACIZE5_002875"
     tRNA            complement(445..517)
                     /locus_tag="ACIZE5_002875"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
BASE COUNT          135 a          152 c          128 g          113 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DBBGSZ010000139          527 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.149, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000139 DBBGSZ010000000
VERSION     DBBGSZ010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.149"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
BASE COUNT          195 a           70 c           93 g          169 t
ORIGIN      
        1 tttttattga acaaaccatg taaaaccaga aaatcagtat actgattttc tggttttttg
       61 ttttttagtt atttatgtaa gattgcttcg ataattctca aaacgaaata agtagggaag
      121 ttggagattt tgattatctt cgtaactgac gaagagtaaa tgaatccatt tggtatgcac
      181 tcttaagttc aaaatattgg tatcgatgtt taaaagaaat agaaatgtat cgaagaacag
      241 atgtttaaaa aagtgtgact ttgtataaat aaattagaag aagcaaacga ggatgttaaa
      301 agaataccat atagttacca aaccaagaaa gttctcgtca agttcgctgg tacgaatcaa
      361 atcaagtgaa aaaagggact gtgaaaaaaa ttgtgtcata gttagtcact ttttccgaac
      421 aaatagtgtt caatcagctg tccttcggta ttagctcaaa aaacggcaaa atatgaggaa
      481 ctatttttcc atttgtttct ctaatactca ggacaaaaca ctgattt
//
LOCUS       DBBGSZ010000140          512 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.150, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000140 DBBGSZ010000000
VERSION     DBBGSZ010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..512
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.150"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..132)
                     /locus_tag="ACIZE5_002876"
     CDS             complement(<1..132)
                     /locus_tag="ACIZE5_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HGC6109934.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          184 a           94 c           92 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag ac
//
LOCUS       DBBGSZ010000141          492 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.151, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000141 DBBGSZ010000000
VERSION     DBBGSZ010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.151"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            126..492
                     /locus_tag="ACIZE5_002877"
                     /pseudo
     CDS             126..492
                     /locus_tag="ACIZE5_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
BASE COUNT          195 a           54 c           86 g          157 t
ORIGIN      
        1 aaagaaggca ctctcttcgg gttttcggtc tgtactgaaa tcaaggtatt attgggaatc
       61 ccagcttaaa tcatagatac cgtaagggat tttattcttt atttaaaact ttgcaacaga
      121 accgtacaag atatattaaa ttgatttttg aatttttgaa aaaagaaaga aatgctaatg
      181 cagttatttt agaccctcat aaaaataatc caagagcaat aagggcatac caaaaatctg
      241 gttttagaat tattgaagat ttgccagaac atgaattaca cgagggcaaa aaagaagatt
      301 gttatttaat ggaatataga tatgatgata atgccacaaa tgttaaggca atgaaatatt
      361 taattgagca ttactttgat aatttcaaag tagatagtat tgaaataatc ggtagtggtt
      421 atgatagtgt ggcatattta gttaataatg aatacatttt taaaacaaaa tttagtacta
      481 ataagaaaaa ag
//
LOCUS       DBBGSZ010000142          486 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.152, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000142 DBBGSZ010000000
VERSION     DBBGSZ010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.152"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..>486)
                     /locus_tag="ACIZE5_002878"
     CDS             complement(<1..>486)
                     /locus_tag="ACIZE5_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGC6109935.1"
                     /translation="LYDEYFDCYICPQDQMLAFSTVTREGYREYKSNPKECVNCPLLN
                     QCTISKNHQRVITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKHGMR
                     WTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQARVTS
                     L"
BASE COUNT          127 a          107 c           84 g          168 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat gactcgttga tgatttttac ttatggtaca ttggtttagc
      361 agaggacagt tcacacattc ttttggattg gatttgtatt ctcggtaccc ttctcgagta
      421 accgttgaaa aagcgagcat ttgatcttgc ggacaaatat aacaatcaaa atactcgtca
      481 tagaga
//
LOCUS       DBBGSZ010000143          470 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.153, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000143 DBBGSZ010000000
VERSION     DBBGSZ010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.153"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..>470
                     /locus_tag="ACIZE5_002879"
     CDS             <1..>470
                     /locus_tag="ACIZE5_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
                     /protein_id="HGC6109936.1"
                     /translation="ALSKRGIQISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKT
                     TNVLNRKFLRDNPLEAIVTDLTYVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLV
                     KKAFSRIKQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHKGCPFDNAV"
BASE COUNT          167 a           78 c           88 g          137 t
ORIGIN      
        1 aagccttatc aaaacgaggc attcagatca gccgacgaaa aattagtaga atcatgaaaa
       61 atagaggatt aaaatcgagc tatactgttg cttattttaa agtacatcat tctacttgca
      121 atgaagccaa aacgacaaac gtattgaatc gtaaattctt aagagacaac ccattagaag
      181 cgatcgtaac agacttgact tatgtacgag tcgggaaaaa atggaattat gtctgtttca
      241 ttttggatct gttcaatcga gaaattctcg gctattcttg tggagaacat aaagatgccg
      301 ttctagtaaa aaaagcattt agccgtatca aacaacctct gacagaggtt gagatttttc
      361 atactgatcg tggaaaagag tttgataacc aagctattga tgaattatta acaacttttg
      421 acatcaatcg atcattgagt cataaaggct gtccttttga taatgccgta
//
LOCUS       DBBGSZ010000144          469 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.154, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000144 DBBGSZ010000000
VERSION     DBBGSZ010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.154"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..>469
                     /locus_tag="ACIZE5_002880"
     CDS             <1..>469
                     /locus_tag="ACIZE5_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HGC6109937.1"
                     /translation="GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETA
                     LNQWFSRFPKNFFKSITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGI
                     LRRNGLPKSMDFRKVNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYS"
BASE COUNT          156 a           90 c           78 g          145 t
ORIGIN      
        1 tggtcacctt gaaggtgata cgatcgttgg cattcatcat aaaagtgccg tcattacttt
       61 agttgaaaga ttatctaaag tcattatcac gattaaaccc aacggccgta aggcattaga
      121 tattgaaact gcccttaatc aatggttttc tcgcttccct aaaaacttct ttaaatctat
      181 tacgtttgac tgtggaaaag aattttctaa ctggaaagcc attagtaacc aacatgatat
      241 tgatatatat tttgcggacc ctggaacacc ttctcaacgc ccattaaacg agaattctaa
      301 cgggattctg cgtcgtaatg gactgccgaa atcaatggat tttagaaaag tgaatcagac
      361 atttatttcc agtgtcagca atcaacgtaa tcatattcca agaaaatcat tgaattacag
      421 aacaccaatc gaaatatttt tgagctatgt acaagaagca ttttattct
//
LOCUS       DBBGSZ010000145          468 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.155, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000145 DBBGSZ010000000
VERSION     DBBGSZ010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.155"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..>468
                     /locus_tag="ACIZE5_002881"
     CDS             <1..>468
                     /locus_tag="ACIZE5_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HGC6109938.1"
                     /translation="CVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLA
                     YTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYF
                     YGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHK"
BASE COUNT          155 a           86 c           83 g          144 t
ORIGIN      
        1 cttgtgttat atggggcata attaatggct atactagcca aagagccacg tatagagcgg
       61 tttgttccgt cttatttcct aatggtgact ttcctagtag gagtcgattc actcgcttaa
      121 gttcaaactt agcttacact atcaagatta ttcgatactt tttcatcaag aagctcacca
      181 aaggtgaact agtcggaatt atagatagtt ttcctagtcc attatgtaaa ccagttagaa
      241 atagacaagc aaaactattg aatcaaatag ccaaagttgg ctataactca acaaaaaaat
      301 cttattttta tggtcttaaa attcatatga tcgttactaa gactggcttt ccgattactt
      361 actcaatcac gaatccaggt gtccatgacg tgaaagtgtt agagacttta tcggaagaag
      421 cgaatcttcc caatatccta ggggacaaag gatatattag ccataaaa
//
LOCUS       DBBGSZ010000146          467 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.156, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000146 DBBGSZ010000000
VERSION     DBBGSZ010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.156"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..>467
                     /locus_tag="ACIZE5_002882"
     CDS             <1..>467
                     /locus_tag="ACIZE5_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HGC6109939.1"
                     /translation="GEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWPEEA
                     TQPITADDTEFVSSATKLDDKSDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKDT
                     KYTWKEKVDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
BASE COUNT          190 a           68 c          111 g           98 t
ORIGIN      
        1 ggagaaggaa caagtattga aagtggaaca acagtctttg cagtgaaaga cggcgtaagc
       61 ttaccagaag ataaacttcc agtgttgaaa gcaaaagatg gttatacaga tgcgaaatgg
      121 ccagaggaag caactcaacc aattacagca gatgatacag aatttgtatc aagtgcaaca
      181 aaactggatg ataaatctga cgctgacaaa tataatcctg aaggtcaaaa agtgactaca
      241 gaattgaata aggaaccaga cgcatttgag ggaattaaga acaaagaaga tttaccaaaa
      301 gatactaagt atacttggaa agaaaaagta gatgttagcg cagctggaaa taaaaaaggg
      361 actgttgtag tgacatatcc agatggatca tctgatgaag ttgaagtaga tgttacagtg
      421 acagacaatc gttctgacgc cgataaatat gagccaacag tagaagg
//
LOCUS       DBBGSZ010000147          455 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.157, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000147 DBBGSZ010000000
VERSION     DBBGSZ010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.157"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..430)
                     /locus_tag="ACIZE5_002883"
     CDS             complement(<1..430)
                     /locus_tag="ACIZE5_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGC6109940.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT          131 a           90 c           58 g          176 t
ORIGIN      
        1 ctgctcttaa acgaataact tcttcttcaa gagactcatc tttaagtttt ttaggaatgt
       61 ttagcttgga attcatacta atttttctgc cccttttttg gctctcaagt gaagaagcac
      121 cgccttcttc atattgctct atccatttac ttagagttct atttgaaccg atattaaatt
      181 ttttagcagt ttcttggata gaaagaccat ttgtttccat atattctata acatcaagtt
      241 taaattttgt agtgtagctt ttgccacctc caaccaagcc ttcccaacca tgatagttat
      301 aaatccttac ccaatgtcta accagtgtac gatttatttg atatttatgt gcaagatatt
      361 tgtagccgcc ttcgttattt aaatagtctg aaactacttt tttcttaaaa acaaatgtat
      421 atttccgcaa aaaaagcacc ccttttaatt agatt
//
LOCUS       DBBGSZ010000148          447 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.158, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000148 DBBGSZ010000000
VERSION     DBBGSZ010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.158"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..>447
                     /locus_tag="ACIZE5_002884"
     CDS             <1..>447
                     /locus_tag="ACIZE5_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGC6109941.1"
                     /translation="HLEKAINTLLRTELTAFLDYEKYDRTGFNSGNSRNGSYFRSIKT
                     EYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLETTIIHLFEKGVTMSEIADLIEKMYG
                     HHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAIFMDATYIPLKRQT"
BASE COUNT          165 a           85 c           72 g          125 t
ORIGIN      
        1 gcacttagaa aaagcgataa acacactcct acggactgaa ttaacggctt ttttagatta
       61 cgaaaaatat gatcgcactg gttttaattc aggtaattcg agaaacggtt cttactttcg
      121 atcaatcaaa accgaatatg gtgaattaac attggaaata cctagagatc gtaatggtga
      181 gtttaaacaa caaactttac cagcctacaa aagaacaaac gatacattgg aaaccactat
      241 tatccattta ttcgaaaaag gtgttacgat gtctgaaatt gctgatttga tcgaaaaaat
      301 gtacggtcat cactatactc cacaaaccat gtccaacatg actaaagttc tgactgaaga
      361 agtaaatgcc tttaaatcca gagccttaaa tgataagtat gtcgctattt ttatggacgc
      421 tacttacatt ccactaaaac gtcaaac
//
LOCUS       DBBGSZ010000149          444 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.159, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000149 DBBGSZ010000000
VERSION     DBBGSZ010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.159"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..>444
                     /locus_tag="ACIZE5_002885"
     CDS             <1..>444
                     /locus_tag="ACIZE5_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGC6109942.1"
                     /translation="IAIGIREDGTKEVLSYAIAPTESTYVWNELLQDINSRGVQEVLL
                     FITDGLKGMKDTIHQIYPKAKYQHCCIHVSRNIAHKVRVKDRKEICDDFKAVYQANSK
                     EEANTFLSGMIEKWKKNYPKVTQSLIENQDLLTFYDFPPSIRRTIY"
BASE COUNT          156 a           84 c           81 g          123 t
ORIGIN      
        1 attgccattg gtatacgaga agacggcact aaagaagtac tgagttatgc gattgctcca
       61 actgaatcaa catacgtttg gaatgagctg ctacaggata ttaactccag aggagttcaa
      121 gaagtcttgc tttttattac ggacggctta aaaggcatga aagatactat ccatcaaatt
      181 tatcctaaag caaaatatca gcattgttgt atccatgtat ctcgtaacat cgctcataaa
      241 gtacgtgtca aagaccgaaa agaaatctgt gatgacttta aggctgttta tcaagctaac
      301 tcaaaagaag aagcgaatac cttcttatcc ggcatgattg agaaatggaa gaaaaactat
      361 cctaaagtga cgcagtcact catagaaaac caagacttat taacttttta tgattttcca
      421 cctagcattc gtagaaccat ttac
//
LOCUS       DBBGSZ010000150          440 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.160, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000150 DBBGSZ010000000
VERSION     DBBGSZ010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.160"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..233
                     /locus_tag="ACIZE5_002886"
     CDS             <1..233
                     /locus_tag="ACIZE5_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGC6109943.1"
                     /translation="LKNLPETLDAQLRTKLQNLLTYEEGIYNAMIYPYSNGKIEAKIP
                     HIKTLKRLSYGFKSFENMKIRIFLINQLIQVK"
BASE COUNT          163 a           80 c           62 g          135 t
ORIGIN      
        1 tattaaaaaa tcttcctgaa acacttgatg cacaacttcg cacgaaactt caaaaccttt
       61 taacgtatga agaaggtatt tacaatgcta tgatttaccc gtattctaat ggcaaaatag
      121 aggccaagat tccccatatc aagacactga aacgattatc ttatggattt aaatcatttg
      181 agaacatgaa aatcaggatt tttttgatca atcaattgat tcaagtgaaa taacaaaaaa
      241 atctgagaca gaaggtcagt ccttctatcg gctctatact ttttgatgtt ggtgaacttc
      301 accaacatct tttttgtata aaaaaatata gaaaagacac cctgaaatcc tttagaatta
      361 atttggctac caattcatag gaggattcaa gatgtctcat actcagctta tcaaagatac
      421 cctaaatatt ctagacctaa
//
LOCUS       DBBGSZ010000151          415 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.161, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000151 DBBGSZ010000000
VERSION     DBBGSZ010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.161"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..339)
                     /locus_tag="ACIZE5_002887"
     CDS             complement(<1..339)
                     /locus_tag="ACIZE5_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6109944.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYT"
BASE COUNT          116 a           70 c           68 g          161 t
ORIGIN      
        1 tgtataactc tgaacaggat ttttcttact tttgaaacgt ggaaatccaa cggatttatc
       61 ccgaaaaaaa ttcttgtatg ctttatctaa attaagttgg gcattggcta aagcaaggct
      121 atcaatttct ttcaaaaacg gaaattcttt cttgtattta gctggtgtcg gaaaagtcat
      181 ttttttagaa gaatcatttt taacttcttc atacgccttt tttcggtcat caagcattag
      241 attgtagacc ttacggacac aaccaaaaga tttggcaaag aagatttctt gttcctctgt
      301 tggatagatt ctgaatttgt atgcttttag ttgttccata aagttcacct actttctatt
      361 tatgattgtt tccttgattt tggatatact tcttaatcac atcaattggt gcgcc
//
LOCUS       DBBGSZ010000152          368 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.162, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000152 DBBGSZ010000000
VERSION     DBBGSZ010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.162"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..272)
                     /locus_tag="ACIZE5_002888"
     CDS             complement(<1..272)
                     /locus_tag="ACIZE5_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109945.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKT"
BASE COUNT          106 a           69 c           52 g          141 t
ORIGIN      
        1 aaagttttga tttgttgcgt gtgttccacc aatttttctg tatgtgtatc taatctttca
       61 tcgtgtttct ttagttcttc atgaatcatc aatcgatctg atttgctcga ttctaaatct
      121 ttagtcagca aatctaaatt gtggcttact tttgaaagag tctcagtaat tttcgagaaa
      181 gatgcagcaa tcggtctaat tactaataaa atcaaagaaa cgatagcggt tattgatcct
      241 gctatcattc cccattcccc taaattaatc atgtgacaac tcctttacct taaataaaaa
      301 cgcatcaatt aagatgcgct cttatcttta ttaatgattt tatctgcttc ttcgtctgta
      361 atgcataa
//
LOCUS       DBBGSZ010000153          367 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.163, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000153 DBBGSZ010000000
VERSION     DBBGSZ010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.163"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..>367
                     /locus_tag="ACIZE5_002889"
     CDS             <1..>367
                     /locus_tag="ACIZE5_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HGC6109946.1"
                     /translation="KIPHFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNL
                     YLDSTHIKANANKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKL
                     KERKISKADPESGYYVKGER"
BASE COUNT          137 a           61 c           80 g           89 t
ORIGIN      
        1 aaaatccccc atttctcaac ttttggaaag aattatgttc gccgatttag agaaacgacg
       61 gtgtttgagg atatttttgc ctatatttta gaacaagcag ttaaagcagg ttttgtaaca
      121 gaggataatt tgtatctgga ttctacccac atcaaagcta acgccaataa acataagttt
      181 acgaaagaaa tgacccatga tgaagcgaaa gcctatcagg atgaattaga agatgagatc
      241 aatcgtcaac gaatagaggc tggaaaacgc ccttttactt tggacttaga aaaggaagtg
      301 aagctgaaag aaagaaaaat aagtaaagct gatccggaaa gcggctacta cgtcaaaggc
      361 gaacgag
//
LOCUS       DBBGSZ010000154          362 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.164, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000154 DBBGSZ010000000
VERSION     DBBGSZ010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.164"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..>362)
                     /locus_tag="ACIZE5_002890"
     rRNA            complement(<1..>362)
                     /locus_tag="ACIZE5_002890"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           72 a          113 c           83 g           94 t
ORIGIN      
        1 aaatccggac aacgcttgcc acctacgtat taccgcggct gctggcacgt agttagccgt
       61 ggctttctgg ttagataccg tcaagggatg aacagttact ctcatccttg ttcttctcta
      121 acaacagagt tttacgatcc gaaaaccttc ttcactcacg cggcgttgct cggtcagact
      181 ttcgtccatt gccgaagatt ccctactgct gcctcccgta ggagtttggg ccgtgtctca
      241 gtcccaatgt ggccgatcac cctctcaggt cggctatgca tcgtggcctt ggtgagccgt
      301 tacctcacca actagctaat gcaccgcggg tccatccatc agcgacaccc gaaagcgcct
      361 tt
//
LOCUS       DBBGSZ010000155          305 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.165, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000155 DBBGSZ010000000
VERSION     DBBGSZ010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.165"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="ACIZE5_002891"
     CDS             complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="ACIZE5_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HGC6109947.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
BASE COUNT           95 a           45 c           50 g          115 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgtt
//
LOCUS       DBBGSZ010000156          295 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.166, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000156 DBBGSZ010000000
VERSION     DBBGSZ010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.166"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(111..>295)
                     /locus_tag="ACIZE5_002892"
     CDS             complement(111..>295)
                     /locus_tag="ACIZE5_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109948.1"
                     /translation="RQHCSTIFLLFFLIFFDYSTPLEKIKRPQGISFPEPLEPPPAEI
                     EWRCQHLFRSAIGYTI"
BASE COUNT           87 a           44 c           86 g           78 t
ORIGIN      
        1 gttctgagcg gttttagcgt ttatttcgtt tagttatcgg cacaatcggt gaaacacgtt
       61 agaggagcga aaatggagcc tgtaaggcga ctggtagcgg aacggtcgtg ttagattgtg
      121 tagccgatag ctgaacgaaa taaatgctgg cagcgccatt ctatttcggc aggaggaggc
      181 tcaaggggtt cggggaatga aattccctga ggtcttttta ttttttctag aggagtgcta
      241 taatcaaaga aaatgagaaa aaagagtaaa aaaatagtcg agcagtgttg acgca
//
LOCUS       DBBGSZ010000157          290 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.167, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000157 DBBGSZ010000000
VERSION     DBBGSZ010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.167"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            37..>290
                     /locus_tag="ACIZE5_002893"
     CDS             37..>290
                     /locus_tag="ACIZE5_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008177227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGC6109949.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDT"
BASE COUNT           88 a           53 c           57 g           92 t
ORIGIN      
        1 atagatttat gaaaacgaat gcaaggagtg atagctatga tgtctaaaaa caatacgaat
       61 ggtagaaatc aatttgcgat gcttacgatt gatgatctag ttcctcaaga tcatctcgtt
      121 cgaaagattg atgccgcgct tgattttgaa tttatttatc caatcgtcga agccacttac
      181 tccgatttag gtcgcccaag tatcgatcca gtgattctga tcaaattggt gtttattcag
      241 tatttattcg gtatccgttc catgcgacaa accattaagg aagtcgatac
//
LOCUS       DBBGSZ010000158          290 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.168, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000158 DBBGSZ010000000
VERSION     DBBGSZ010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.168"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..>290
                     /locus_tag="ACIZE5_002894"
     CDS             <1..>290
                     /locus_tag="ACIZE5_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HGC6109950.1"
                     /translation="VGYYLRYNLSYREVQEILYDRGINVSHTTIYRWVQEYGKLLYQI
                     WKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWLRKKRDTQAA"
BASE COUNT          103 a           46 c           56 g           85 t
ORIGIN      
        1 gtgggctact atcttcgtta taaccttagc tatcgtgaag ttcaagaaat cttatatgat
       61 cgtggcatta acgtttctca tacgacgatt tatcgttggg tgcaagaata tggcaaacta
      121 ctctatcaaa tttggaaaaa gaaaaataaa aaatcctttt attcatggaa aatggatgaa
      181 acgtacatca aaattaaagg aaaatggcat tatttgtatc gagccatcga tgcagatggt
      241 ttaaccttgg atatttggtt acgtaaaaaa cgggacacac aagcagccta
//
LOCUS       DBBGSZ010000159          280 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.169, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000159 DBBGSZ010000000
VERSION     DBBGSZ010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.169"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..>280
                     /locus_tag="ACIZE5_002895"
     CDS             <1..>280
                     /locus_tag="ACIZE5_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="replisome organizer"
                     /protein_id="HGC6109951.1"
                     /translation="KNVLLSDEQMEKLKTEFPNDYQERIERLSEYCESSGKTYKNYLA
                     TIRSWARKEKSEPKNASSGYKRTGRREKLPEWAIDQEAYLKKKALERA"
BASE COUNT          112 a           49 c           64 g           55 t
ORIGIN      
        1 ataaaaatgt tcttttgtca gatgagcaga tggagaaact caaaacagaa ttccctaatg
       61 attaccaaga gcgaatcgaa cgactgtcag agtattgtga atcatctggt aagacttata
      121 aaaactattt ggcaactatt cgaagttggg caaggaaaga aaaaagtgaa cctaagaacg
      181 caagcagtgg atacaagcgc acaggaagac gagagaagct tcctgaatgg gcaatcgacc
      241 aagaagccta tctcaagaaa aaagcgctag aacgagctaa
//
LOCUS       DBBGSZ010000160          275 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.170, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000160 DBBGSZ010000000
VERSION     DBBGSZ010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.170"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..>275
                     /locus_tag="ACIZE5_002896"
     CDS             <1..>275
                     /locus_tag="ACIZE5_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGC6109952.1"
                     /translation="FICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLVMD
                     MNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTS"
BASE COUNT           80 a           65 c           48 g           82 t
ORIGIN      
        1 tttatttgtg ttgatgggac aaccaatcag ctatttacga tccttgaaga tcgcagactt
       61 tacaaactaa ctcaatactt cctgcgcttt cctagaaagg cccgtttaaa ggtcaagtac
      121 ctagtgatgg acatgaatgc cagctattgt cagttgctta aaacagtctt tccaaatgcg
      181 gagatcgtaa ctgaccgctt tcatattgtc caacacatca atcgcagctt caatcaatta
      241 cgtgtccaga tcatgaatcg ttttcgaacc tcaca
//
LOCUS       DBBGSZ010000161          264 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.171, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000161 DBBGSZ010000000
VERSION     DBBGSZ010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..264
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.171"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            83..>264
                     /locus_tag="ACIZE5_002897"
     CDS             83..>264
                     /locus_tag="ACIZE5_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGC6109953.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
BASE COUNT           83 a           55 c           43 g           83 t
ORIGIN      
        1 cctatgaaat attttcacgt gttaaagtat tcctcgttga acacaacaaa taaaactttt
       61 taacgaataa aggagatttt tcatgacatc acttaaaact ttactttttg gaacaacttt
      121 ggctgccggc gctgcattct tcatgggaac gactgctcat gcggacgaag cttataccgt
      181 tcaatcaggt gatactctat caacgatttc tcaaaaatac gttggtgata actccttgat
      241 caatgccatt gcagaatcaa attc
//
LOCUS       DBBGSZ010000162          261 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.172, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000162 DBBGSZ010000000
VERSION     DBBGSZ010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..261
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.172"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..>261
                     /locus_tag="ACIZE5_002898"
     CDS             <1..>261
                     /locus_tag="ACIZE5_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109954.1"
                     /translation="PGQAATITIGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPG
                     INATTTAVATTTANGLMSSTDKTKLDGIAAGAQKNPGNATTTT"
BASE COUNT           87 a           54 c           56 g           64 t
ORIGIN      
        1 tcctggccaa gcagcaacaa ttaccatagg aaccgtttct agtggttcaa ccgcttctgt
       61 tacgaatgta ggaacatcat ctgcagctag atttaatttt gttttaccaa agggagataa
      121 aggtgatcct ggaataaatg ccacaactac agctgtagct acaactacag caaatgggtt
      181 gatgtcgtcc acagataaaa ctaagttgga tggaattgca gctggagcac agaaaaatcc
      241 aggtaatgct acaactacga c
//
LOCUS       DBBGSZ010000163          253 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.173, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000163 DBBGSZ010000000
VERSION     DBBGSZ010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.173"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            <1..>253
                     /locus_tag="ACIZE5_002899"
     CDS             <1..>253
                     /locus_tag="ACIZE5_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tip lysozyme"
                     /protein_id="HGC6109955.1"
                     /translation="GFTKQSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSY
                     PLVGPATWDGKVYVQNLFNAAGIKEPITSLDAQVRLLIWT"
BASE COUNT           80 a           40 c           58 g           75 t
ORIGIN      
        1 ggatttacga aacaatctgc atgtggaata ttggggaaca ttcaacaaga aacaggagga
       61 acttttgatc ctgatactgt tcaaataggt ggaccagcat acggattagt tcagtgggat
      121 ggttcttcat atcctcttgt tggtccagca acatgggatg gaaaagttta tgttcaaaac
      181 ttatttaatg ctgcaggtat taaagaacca ataacgagct tagatgcaca agttcgattg
      241 cttatttgga cat
//
LOCUS       DBBGSZ010000164          241 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.174, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000164 DBBGSZ010000000
VERSION     DBBGSZ010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.174"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
BASE COUNT           88 a           27 c           43 g           83 t
ORIGIN      
        1 attttagcta tattagcttt ttccgaaaat aaacaacctg taactgcaaa aaaagaaaca
       61 gtattctctg aaggcaaaat aaaaactcga tatatattag aggtagagac taagtttaaa
      121 aatagatcgg agtaatggtt atgcttttta atgagacgca attatggttt aaatttgatc
      181 cttcgaatag atttgtcaaa gatttttata aggtgtggga ttcagaagtt ttctttttag
      241 c
//
LOCUS       DBBGSZ010000165          238 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.175, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000165 DBBGSZ010000000
VERSION     DBBGSZ010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..238
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.175"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(18..>238)
                     /locus_tag="ACIZE5_002900"
     CDS             complement(18..>238)
                     /locus_tag="ACIZE5_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HGC6109956.1"
                     /translation="NKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIITGF
                     GAFLGSVLGVSNRTYKMFSAESEEGGNK"
BASE COUNT           70 a           57 c           37 g           74 t
ORIGIN      
        1 aatagtaatt ttctttttca tttgtttcct ccttcttcgc tttcagccga gaacattttg
       61 taggttcgat ttgatacacc caacacactc cctaaaaacg cgccaaaacc agtaatgatg
      121 acaacacaga tatctgtgta ctgccaattg agcgctttac caactaaccc cacgaaagta
      181 gctagtgcgg gaataattac cagtgcgaac cattttagta cttcgaacgt tttattat
//
LOCUS       DBBGSZ010000166          236 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.denovo.176, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000166 DBBGSZ010000000
VERSION     DBBGSZ010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.denovo.176"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
BASE COUNT           68 a           58 c           36 g           74 t
ORIGIN      
        1 acctttctgt tactctttga caaagagtaa cattttccta attgtgacat ggctgtcaca
       61 attccaaatg ctctccgagg gtattcgctg tcacaagtga caacgaaaaa aggagccgaa
      121 agcgtgtcac gctctcaact ccttttacgc tttattttgc ttcacgcaaa ataatcgctt
      181 atcgtaaact cacgtcatta aacattgacg taaatttact ctcactcatc tgactt
//
LOCUS       DBBGSZ010000167        26328 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.guided.036, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000167 DBBGSZ010000000
VERSION     DBBGSZ010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.guided.036"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(172..2310)
                     /locus_tag="ACIZE5_002901"
     CDS             complement(172..2310)
                     /locus_tag="ACIZE5_002901"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGC6109957.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(2349..3935)
                     /locus_tag="ACIZE5_002902"
     CDS             complement(2349..3935)
                     /locus_tag="ACIZE5_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC6109958.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            complement(3925..5145)
                     /locus_tag="ACIZE5_002903"
     CDS             complement(3925..5145)
                     /locus_tag="ACIZE5_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6109959.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            complement(5157..5963)
                     /locus_tag="ACIZE5_002904"
     CDS             complement(5157..5963)
                     /locus_tag="ACIZE5_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6109960.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            complement(6173..7453)
                     /locus_tag="ACIZE5_002905"
     CDS             complement(6173..7453)
                     /locus_tag="ACIZE5_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HGC6109961.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            complement(7497..9530)
                     /locus_tag="ACIZE5_002906"
     CDS             complement(7497..9530)
                     /locus_tag="ACIZE5_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109962.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            complement(9564..10415)
                     /gene="rfbD"
                     /locus_tag="ACIZE5_002907"
     CDS             complement(9564..10415)
                     /gene="rfbD"
                     /locus_tag="ACIZE5_002907"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HGC6109963.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            complement(10513..11541)
                     /gene="rfbB"
                     /locus_tag="ACIZE5_002908"
     CDS             complement(10513..11541)
                     /gene="rfbB"
                     /locus_tag="ACIZE5_002908"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HGC6109964.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            complement(11563..12135)
                     /gene="rfbC"
                     /locus_tag="ACIZE5_002909"
     CDS             complement(11563..12135)
                     /gene="rfbC"
                     /locus_tag="ACIZE5_002909"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HGC6109965.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            complement(12149..13015)
                     /gene="rfbA"
                     /locus_tag="ACIZE5_002910"
     CDS             complement(12149..13015)
                     /gene="rfbA"
                     /locus_tag="ACIZE5_002910"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HGC6109966.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            complement(13115..13822)
                     /locus_tag="ACIZE5_002911"
     CDS             complement(13115..13822)
                     /locus_tag="ACIZE5_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGC6109967.1"
                     /translation="MRSVCIATFNGGRYLREQLDSILSQLSAEDEVVISDDGSVDDTW
                     DILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWLETKVKKITD
                     YFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYIGAGMAFRSS
                     LKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIETHSKLRQKIS
                     WRVHLITALIKRKWFKR"
     gene            complement(13827..14654)
                     /locus_tag="ACIZE5_002912"
     CDS             complement(13827..14654)
                     /locus_tag="ACIZE5_002912"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGC6109968.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            complement(14654..15454)
                     /locus_tag="ACIZE5_002913"
     CDS             complement(14654..15454)
                     /locus_tag="ACIZE5_002913"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGC6109969.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            complement(15447..16586)
                     /locus_tag="ACIZE5_002914"
     CDS             complement(15447..16586)
                     /locus_tag="ACIZE5_002914"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HGC6109970.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            complement(16791..17984)
                     /locus_tag="ACIZE5_002915"
     CDS             complement(16791..17984)
                     /locus_tag="ACIZE5_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6109971.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(18063..18269)
                     /locus_tag="ACIZE5_002916"
     CDS             complement(18063..18269)
                     /locus_tag="ACIZE5_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HGC6109972.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            complement(18262..19404)
                     /locus_tag="ACIZE5_002917"
     CDS             complement(18262..19404)
                     /locus_tag="ACIZE5_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGC6109973.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            19916..20551
                     /locus_tag="ACIZE5_002918"
     CDS             19916..20551
                     /locus_tag="ACIZE5_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6109974.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            20687..20779
                     /locus_tag="ACIZE5_002919"
                     /pseudo
     CDS             20687..20779
                     /locus_tag="ACIZE5_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323349.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            20893..21528
                     /locus_tag="ACIZE5_002920"
     CDS             20893..21528
                     /locus_tag="ACIZE5_002920"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6109975.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            21635..22873
                     /gene="mef(H)"
                     /locus_tag="ACIZE5_002921"
                     /gene_synonym="mefH"
     CDS             21635..22873
                     /gene="mef(H)"
                     /locus_tag="ACIZE5_002921"
                     /gene_synonym="mefH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_070509550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide efflux MFS transporter Mef(H)"
                     /protein_id="HGC6109976.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            23100..23519
                     /locus_tag="ACIZE5_002922"
     CDS             23100..23519
                     /locus_tag="ACIZE5_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HGC6109977.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            23524..23763
                     /locus_tag="ACIZE5_002923"
     CDS             23524..23763
                     /locus_tag="ACIZE5_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6109978.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(23988..24911)
                     /locus_tag="ACIZE5_002924"
     CDS             complement(23988..24911)
                     /locus_tag="ACIZE5_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HGC6109979.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(24943..25707)
                     /gene="map"
                     /locus_tag="ACIZE5_002925"
     CDS             complement(24943..25707)
                     /gene="map"
                     /locus_tag="ACIZE5_002925"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HGC6109980.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            25865..26305
                     /locus_tag="ACIZE5_002926"
     CDS             25865..26305
                     /locus_tag="ACIZE5_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HGC6109981.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
BASE COUNT         7976 a         5320 c         4564 g         8468 t
ORIGIN      
        1 aaatttgaaa agcaattttc gtgaatttct tcttatttct cggagttaaa cacttctgtc
       61 ccaacctcga cttatttttt tgagtcggca ccttctgcct ttttttgaca aaaaactata
      121 aaaagccgtt atgtgcgagc gaatcacaac ataacagctt tttattatag tttaatctgg
      181 tctcaacgaa aagtcgccga ttccttcttt tgttaaatta tcattgtaaa atggatcatg
      241 cgcaatatat gctggccatt tatcttgcat ttttttgatt tcaccagcaa aacgtctttg
      301 tttttctgga gtatcttcat aacctcttga tttagattcg aaatggtaca attctgcttg
      361 atgtgcatag acattgtaac gacccagttc ataaactttc aagcacaagt caacatcgtt
      421 gaatgctact tctaatgttt catcaaaccc gttaacagca ttgaagtcag ctgccttgac
      481 catcatacaa gctgcagtga ctgctaagta attgacgtca atgaccaatc ggccgaaata
      541 accacaatgt gttcgatcat agttattcaa tgcatgccct gcaacaccac cgattcctaa
      601 taatactcct gcatgctgcg ttgtatcatc tggataaaac agttttgctc ctacacagcc
      661 gattcgatca aactgtgcat aagaaaccat caccgtcatc caatctggct caatcacttc
      721 tgtatcgtta ttcaagaata aaaagtattt gccgtttgct ttttctgctg ctaaattgtt
      781 aattcgagaa taattgaatg gaatgtcaat caattctacg ataaagcggt ctttcagctg
      841 atgcttgtat tctgcaaata attcttgcat ttttggatct gtacttccgt tatccgcaat
      901 aatgatttca taatttgaat aagacgtttt ttcgatgatc gaatccacac aagtttttag
      961 atcttcatag ccattcttcg ttggaatgat cacactgacc aaatcctctt gcaagacgtc
     1021 ataagcaatc tcataaaatc cagaaattct gccaggacgt acgcttcctt tgatgtttct
     1081 tctagacagg gcatctgtca atgctttcac tccggaatca tagatataac ttttggcttc
     1141 gccattactt gcagttgatc ctgggatcgt ccgccaatga tacaagactc ggtcaatgtg
     1201 gtaaatatga tctgcaggga tttgttctgt cacacgaagg accaaatcat aatcttgaga
     1261 accttcatag cctttacgga aaccgccaag ttctttaaca atgcttgttc gatatacgcc
     1321 taagtgagag atataattat ttcccatcaa tgtatcaggc gaccagtctg ctttgaaatg
     1381 cggatcaaag cgattgccat ctgcatcgat tttatcttcg tcactgtaga tcacatccag
     1441 ttctggatgt acgtttagca cttttgccac ttcatataat gcaaatggcg gtaattcatc
     1501 atcattatct aagagtgcta taaattctcc ttctgctatt tccaatgcag aattagttgc
     1561 cagactgatg tgtccatttt cttttcggaa aacgactttg attctatcat cttttgcttg
     1621 ataggattcc agacactttc ggatagctgg atcagtagaa gcatcatcac tgatacatag
     1681 ttcccaatga tcatacgttt gatccagtac cgaatcaatg catttttcga gccatttgat
     1741 ttcaacgtta tagacaggca taagtatgga aatcaatgga cggtacgcaa atccttgtgc
     1801 ttctttcctt tgctctttca aatctggttt ctcatgacga ctgatccact ctgcatagtc
     1861 gatcgatcct ggcttcaatt ccaatttgac ccgacggatc gcttttttta cgccatgagt
     1921 ccttgcataa tttatccctt ttttcagtaa tctttttttt ctttcccatg aagattcaat
     1981 gccgtcatca taagggtatt taccgtttaa tttcacagct atgccatttt gatgtctcgc
     2041 tgtttggaag tctaagatgg cttttcctct cattttccct gataaacgta ccttaaaacc
     2101 gctttgggtc ttaacatcaa gattatataa atgattgata tccaatctta cgacatgtgt
     2161 tgcttcagca atcacatttt ctttttctac ctttatcgta gggatttctt tggtcacttc
     2221 atcaattgcc cagcccacaa taagcaaatc gccagtggcc cgttcacgag tgatttgatc
     2281 gataaatacg gcaatttctt ttttttgcac gattcgttta ctccttatct ttataagtta
     2341 atcattattt acatttcaat gatccatgat tggccatttt gagctactgc ttccactaag
     2401 aatgaacgtt cttgctcgca aaggattcgt aactcaaatc ccgcttctgt tccttttgcg
     2461 agctgttctg cttgattgac ttcttctcgt gaaacaggaa ttgcttcgaa aaatggcgat
     2521 tggtcagctg ataacttata ggacaagggc tggcgatccg aattagcgat tccccatccg
     2581 atgattttta atatttttgt ttctgcatcc cagattttct cgtcaataca tatagaaagt
     2641 tctttttctt ggattttttt cgaagtttct ttcttacgtc gtcctagtct atgttttatt
     2701 gtccattcat cactttccaa caatgtgcaa tagcgatttg tggttgtttt taacgtatgg
     2761 tctagtcttg tattttcctc aagaagatga tgattttctc tttctaattc gtcatttttc
     2821 tcagaaagct gctttgtgac ttcagccatg ggacgaatcg tttccaacaa ttctttcatt
     2881 gttggtgtca attccccgat aaagcgatag tgacaatgga tagtcacttc tttcccagaa
     2941 atatccgtta gaacgaactc tggtaattct ttcccatcaa acaaataaca atcatttact
     3001 gttttgacta cagcattcga atcgataaat gttagttttt ctccggcagc ttctgcgctg
     3061 aattcgataa agctaggttg ttgcgcgaag cgaaacacca ttctttctgt tgtttctgat
     3121 acggggaaac ttagtgtctc attttcccct gtgaaattat tgaatggtat ttgttggatt
     3181 gtttcatctt gtttcgtttg ctgggttact tctaacactt ttacataatt agaattttgt
     3241 ggctctgcaa tggaactttg tgctactgga tgtttcatca atgagaaaaa gtattggtag
     3301 acttcaccaa atggtcgcat tttgaaatca tagcgtacag cttccggcaa ttcttcataa
     3361 gttgatttta attctgtatc acctacagct aagtacaaat aatcttcaat attaatgaat
     3421 aatcccgctt tttcaaaaac tttttggaag ccatcatgag tataaaaaga attatgggtt
     3481 tcatctagga gaccataaga agcccacggc aattggttat tgaacaaatc gatcatgaca
     3541 gaattatgcg ccaagttagg gaatgtaatc aggatctctc cttcttcatt caaaaattct
     3601 ctgactttct tcaatgtttt tccaggatct accaaatgtt ctaaaacatc cgcaaacaag
     3661 acgtaatcaa atgtctgtcc agcataatag tttgcccact caaaactttc gatatcacca
     3721 taaaatccat cttgagcaaa ttcgctgaca aaatcgaaca attccttatc taactcaaca
     3781 atgctcactt cacattgttt tgctccgatt aaatgtttcg ttaatcggcc gtttccggga
     3841 ccaaactcta aaactttact tcctggtttg atctgtgcgg caatttttcc cacactgctt
     3901 tgttcatcta ggtccatttc aaaatcatat ttcattgcta tgagtccctt cttcccattt
     3961 atggtctaag accacgatgc cttctccgat ataagaaccg ctgacaaaca agttcatgta
     4021 ctttgtctta tataccaaag gaaccgttgc attttcttca aagaccgcaa cgtcaaaata
     4081 atattcacca gctaacaaac ctaacttttc atactccaga taaaagatat tctctccttt
     4141 tttccaagga atcttgatac catctagtag agtattaagt ccgcatacat aaaaattgtc
     4201 gactgttcgt agcgcaattc ctaaaaccgg atttttgatt gtatcatctt ttacttcata
     4261 agttacttta acgtatagtt tttctccttg ttccagcata tccaccggat ttttgtcttt
     4321 atccaacaat tccgctttcg tcacgtcgac gatatctgga gcggcgaacc gttctacttg
     4381 gtttttattc cgatccactg ttttaactga ttttttcttt aaaaagtttt cataattcgt
     4441 cgttacttcc atcgtatcgc catattcgac gacttctccg tttttcaacc aataggaacg
     4501 atcacaaaaa cgacgaatcg aactgatatc atgagaaacg aataaaatcg tctttcccga
     4561 gttcttgatt tctgtaaatt tttccataca ttttagttga aattcaagat cgcctactgc
     4621 caatgcttca tccacaatca aaatatcggg attcacattg attgctacag caaaagctag
     4681 acgaacgaac atcccgcttg aataagtttt tacaggttga taaatatggt ctccgatgtc
     4741 agcaaattca atgatatcat cgaccatttc atcgacttct tctcttgaaa atcctagaac
     4801 cattccattt aaatagatat tttcatagcc agaatactca ggattgaatc ctgatcctag
     4861 ttctagcaaa gctgagattt ttccttcgat ttccatcgtg ccggatgttg gtgtcagtac
     4921 tcccgtaatg attttcaaca ttgtagattt tcccgatccg ttttctccca cgaaaccgat
     4981 catctcacct ttttttattt ctacattcac gtttttcaac gcataaaata catcatgata
     5041 ggatttctta aaaggattga gggcttcacg aaatcgatcc gaaggttttg cgtacatatt
     5101 ataagatttt gtgatatctt ttagtctaat tgcatattct gtcatagcta ttctccttac
     5161 agcacatctg aaaaatgtgg tttcaatcta cggaacactg cagagccgat tacgaacatt
     5221 actaacgtga aaacccagaa atacaaagta tatgttccat gctcccagaa ccaagcttca
     5281 cttaaaaatg actcacgata accttgaaca acatagtaca gcggatttaa tttcaatatg
     5341 cttacaagac ctgaatcaaa ctgattaggg ctccataata tcggtaatgt ccacatgatc
     5401 aactgcagca cgatcgtaat taattgcatg atatcaggta aaaatggttg gatcgatgcc
     5461 gtcagccaag tcaatcctgt caagaaagca cacatgcaaa ataaataata aatcagctgt
     5521 aaagacattg ctgaaggata tataccattt ataagcgcga cagctatgcc aatcagaatg
     5581 aagaataagt gggtgtacag attggatagg attttcgtcg tgggcaagat acgaatattg
     5641 aatacgactt tctttactaa ataagtatat tcccgaaaaa caaccgtagt tgatgcaaat
     5701 gcatctgaga agaagaacca gggaatcatc ccggtaacta aatatacgat aaatgggtat
     5761 tttgcatcga tcatttgtgc tttcagtcca acaccaaata ccagccaata aatcaataca
     5821 gtaaatagcg gattgataaa cgcccataag attcctaaaa acgatcctgc atatcttgat
     5881 ttgaagtcat tgatcgaaaa ctgtagcaat aattttctgt tctgataaat gtccttcata
     5941 aataaataca aatctttaaa catttgtgtt cctccaagcg attttcagtg aattacagtc
     6001 aagtgccatt ttaccatatt tttggtaccg agctgcgttc ttatttcttt cttaattttc
     6061 tatgatacaa gattttctct aacgtttcta ttttacagaa gatgctagac aattgcaata
     6121 aaccaaaaaa ggctgcgacg gttgtcacag cctctctcgt attttgtgcc tatcaatgat
     6181 agcgttggat cctggaagaa tgagcgctat ctggttgttc ctcataagat gtatcatcat
     6241 aagtcatatc gtcatatgcc tcttccataa catagaattc ctccgcaact tctggttcat
     6301 catatcgatg aacggccata gccaacagga tataaataat cggaacccat gggtatgaag
     6361 tcaatgtatc ctccataaat gactgcatca tcaccgcaaa aaaggcccag ataaaagtca
     6421 tctgcccgtt ggataaatct gctttcaacg ttaagcgacc aataaaaagg ataagcagca
     6481 aagcagcaat cccaaatcct atcaatccat agatattcaa aatagaatta taactattgt
     6541 ggtttcctaa aaattggttt cctcgttgga agataaatgt tttcattcct agtaaaattt
     6601 gttcagattt ttctcctagc gtctgataga atttatgcca aatatcttct cgaccggtaa
     6661 acaaattgac tttttcagag acagccgcca gataagaaat cggcaaagct aaaagaatcg
     6721 taaccgtgta agcaataaat ggcgcacgaa tgacacgcat caacgattta ggtaaaagat
     6781 ccaatatcgc aaaaacaatc aacgcgacta atgcacctct agattggcag acccaaatcc
     6841 cgagaaaagc tgcaacaact gctactgcac cgatgattcg tacataccat cgttcaaaag
     6901 aactggcaaa tccactgatc aataaagcaa gagtcatcaa agaacttccg attatattcg
     6961 tattgatcca aatatcagaa agcgaattgc ctggagccca gatgctttgt ccttctggta
     7021 cttggatctc tgtaaataca cgatataacg tgattccgag gaagaccgaa aagacaatca
     7081 gataaatacc gcgatcccat tttgtccact cgatccattt aattactaaa caaaataaaa
     7141 taatcaaagg aaacagtaag tctccaaata aagactcatt tcttaattcc cgaaagtaag
     7201 aaaagaaaat gaaaagggca agcgcaacac ctagataaag aaaatcgacg ccttttgctt
     7261 tataaacatt taaaatgagc aaaatagcca cactaaaagc gataagtaat gaactattgt
     7321 tatatataaa caaagttgct ggaaaaccta accctgctgt ccaaacaaaa aagactagcg
     7381 tcagtaacaa aagcaagaaa ccgacactca ttttgttgac aaatttttgt acgattgctt
     7441 gaattatctc cactctcctt tctactaaca tttcaggatt attctcagct agcctattac
     7501 tgtacgacta gctgattttc ctgagtttgt gtttgtggta catctggata atccggatat
     7561 tctactttaa aaatcatata accgtcttta tccggtccat atagctgcgt gaactgcgct
     7621 tcatataatt ggttgtaatc agttaatggt cgtttactga tcacatagtc gatccctaat
     7681 ttttctgcgt cttcaaaatt caacgtgacc gaaaacatat ctggacgatc taaaatgaac
     7741 tttgtatctt ccttagcgat aaaagctctt gtatgagcat accgattata atacttctcg
     7801 tattcttctt tcggatcgat tttcttccat gcagctatat ctggataaaa gcgtactgta
     7861 ttgaaggatt tcactcccaa tgttggggtg aagttatata attcatcttc agacaaccaa
     7921 actttaccag gatcttgttg atcgattttt tggatttctt ttgccagtgt tttttcaaaa
     7981 atcgctcctg taccttctac gactggattg acgaaaaagc cagatacgat aactaaggcg
     8041 gcaaaagcga ggtaaaacaa gcgtctccag ccaaataatg caaaagctaa aatcactgtt
     8101 cccaacacag caactgcgat ggtttcaaaa tccgaaaaat aattatccat tttcgaatgc
     8161 gtaatcgcat agaaataaga ccatgcattt actgccaaca aaatgaattt ataccaaata
     8221 ggaataacat cttctctcca aatataagcg ataaaccaga tcgataataa acaagccgca
     8281 aaactaaaag taaggatggc tcttaatgga ggaacataag acagcagagt gatttctgct
     8341 agccattttg gcaacccaac ggtaatccaa aagatagaaa acagacaaaa aatcatcaaa
     8401 atacgtccca gtaacttttg ttcgctatct tttttgccaa ataacacaaa tggacttgct
     8461 aggaatacag ttggaaaaaa gtgatagaac agggccactt cagagttatt cgaatagttg
     8521 atatcttcaa aaggaatttt ccaatttgta aggaaagaaa aaaattcgcc aatcgtccac
     8581 tttcctccag tacttacccg ttttcctgga tataaggtat tcaaagaagc taacaatgcg
     8641 tcttttgacg ttagccagaa atgaaccatg actccgccaa taaataaaac tgcccctcca
     8701 atcaacacta catccaacag atcccatgaa actttcttgc tatagtaaat aagcaggcca
     8761 acaaaataaa aaatcagcaa gtacgccagc atcacttgat gggctgggta aatcactaaa
     8821 ataaacccaa taccgaaaat aaccaccaaa agcatcatca acgttcgtag ccatttttta
     8881 tcatgattgt agaaataatg ataaaaagca gtcatcagtc ccaaagtaaa gaaaatcaaa
     8941 tcgcccacat gttgcatgaa ccaccactgg actgctggag aaaatgtcag cgcaaatgca
     9001 ccgattagcg atagagcttt ttttctcttc gttaatatca tcagtacttc gaatccaagc
     9061 aagaccatga cgactaattt catcgcccaa taaaaggaaa gtcctcgatc tcttccgagg
     9121 aaaaagaatc cccagttgaa tggttttccg ataaccgtaa tatcctttac aggagaatta
     9181 tacgcaatga tcatgttttg tccgtttaat gaataatcct cgttcaccaa cggaaagtcc
     9241 tcttcagctt gtgagaggta aaaaggtgtc tgcaccagcc attcgtctga ccgcacttcc
     9301 cgattctgtc caaaaatcac atcagttttt ttcccatcgt ctctttgcga cacatattta
     9361 tcccaaacac caagtgaact tccgtttaaa ttaaaagtaa cgatgaccac gatgactaaa
     9421 acgccaataa gatagcggag ttttagaaac aggtcaagca ccaaattcga atctgcctgg
     9481 ttcgcttttg gcttttcttt tcgtcgtgca cttcttgttt gtttttccat atcatgctcc
     9541 aaattctatt tgataaaagg aaattactta ttcatttttt tggcagcttc cagcatttgc
     9601 gcaagtgctt cttgccaagt tggtatgaca aatcctaact cttctgtctt tttcaggctc
     9661 atgactgaat actgcggacg tgttgctttt tgcggaaatt cttctgacgt aacaggtgca
     9721 acttctacat ctgtatcttt caatatttct tttgcgaatt cataccaaga acagctattt
     9781 tcgttcgaca aatgataaat accaaatggt gctttttctt cgatgacata taccataaat
     9841 tctgccaaag tacgtgtcca agttggtcgc ccaaactggt catttactac agtcagtttg
     9901 tcgcgggttt ccgctaggcg ttgcatcgtg aagacgaaat tgtgtccata gatcccgaaa
     9961 acccaagaag ttcgtatgat ataatagtct tctaaaatct cttctactgc tttttcgcct
    10021 aataatttcg tacgaccata ttcatttagt ggattcgttt ggtcgtctac ttcgtattct
    10081 acatttttgt tttttccatc gaaaacatag tctgtactga tatagacgaa ttgagcattc
    10141 acagcttttg ctgcaagtgc tacatttctt gtaccatcaa cattgatctt ctcatctaat
    10201 tcttttgctt cttcttctgc tttatctact gctgtgtaag ctgcacaatg gaaaataaca
    10261 tcaggtttta attctgtgat gtaagccatt gttttctcgg catctgtgat atccaagtct
    10321 tttgcatctg ttgaaacata ttgcagattt ttttcatcta ataaatggcg caattctgta
    10381 cctagttgcc catttcctcc agttaataaa aacatatgat tatccgctcc ttgattttta
    10441 ttttaaaaaa gagacaggcg agcgcctgcc tcacatgtgt ttttccatta atacagtgac
    10501 attttctctg tattattgtc catttttggc atatgctgct tcaacggcct ctttttcttt
    10561 tttccaccag tcttcatgtt cttcgtacca tttgatcgtg tcagccaacc catcacggaa
    10621 gttcgtaaac tcaggcttcc atcctaactc ttcccgtaat tttgtcgaat cgattgcata
    10681 acgcaagtcg tgtcctgcac ggtcgtttac atggtcgtac gcatcttttg gttgacccat
    10741 catttctaag atcaattcca tcacggtctt attatcttct tcaccgtctg caccgatcag
    10801 ataggtttcg ccaattctgc ctttcgtcaa aatcagccac actgctgaag aatgatcatt
    10861 cgtatggatc cagtcacgaa cattctttcc ttcgccatat aattttggac gaataccgct
    10921 taagatattc gttacttggc gaggaataaa tttttcaata tgctgataag gaccatagtt
    10981 gtttgaacag tttgaaatgg ttgcacgtaa gccaaaagaa cgcacccatg cttttactaa
    11041 cagatctgaa ccagcttttg tagaagaata tggacttgaa ggattatatg gtgtttccgc
    11101 agtgaatttt tctccttcgc cttccccatg tcctggcagg tcttcacgta atggaagatc
    11161 gccgtaaacc tcgtcagtag atacgtgatg atagcgtaca tcatacttgc ggcaagcttc
    11221 taaaagtgta tacgtaccaa tgatattcgt ttgtacaaat gggaaaggat cttttaatga
    11281 attatcgtta tgggattctg ccgcgtaatg aacaactgcg tccgcttctt ttactagacg
    11341 gtccactaat tctgcatctg caacatctcc tacgaccaat tctacgcgat cgctaggaag
    11401 tccagccaag ttctctttgt ttcctgcata agtcagttta tccaaaacag tgacatgcac
    11461 ttctggatga ttgtttacca cgtaatgaac gaaattagag ccgatgaatc cggcacctcc
    11521 ggtaacaatg atgtttttca taagaaaatt tctccttaat tcttagattt ctccgtaaac
    11581 aaatggattt tctgcttcaa attcttttaa tgtcggatga cggtgatctt tttccgacat
    11641 aatcgctctt gatggatcaa ttggccaatc aatcgctaaa tctggatcat caaatgcgat
    11701 gcccccatct gcttctgcat tatagtaatt atcacactta taaaggaagt tcacatttgg
    11761 tgtcaaagta acgaatccat gggcatatcc tttaggtaca agcaactgtc gatgattatg
    11821 ttcagataag ataaatccgt cccattgacc ataagtcggg ctacctttgc ggatatccac
    11881 tactacatct aaaactgctc cagtgactac ccgaatcaat tttgtctgtg cagcttctcc
    11941 tttttggaaa tgaagccccc gaaggacacc agcttcagct gatagtgaat ggttgtcttg
    12001 aacaaagtca tatttcaatc catgttctgc aaattttgct tttgaataac tttctgtgaa
    12061 gaaaccgcga tgatcgccaa agacgtccat ttctacgatt ttgacatctg ttaattttgt
    12121 atctgttact ttcatctgta aggactcctt attcagcggc caaattcaat aaatattgac
    12181 cgtattgatt ttttttcaat ggctgtgcaa gggccagcaa ttgttcctta tcgatgtagc
    12241 ccatacggta agcaatttct tccaaacaag ccacttttaa gttctgacgt ttttcaattg
    12301 tttcgataaa ggtagatgct tcaagcaatg attcatgtgt tcctgtatca agccaagcaa
    12361 atccgcgtcc cataagttct acggatagtt ttcctttatc caaatatgct ttattgacat
    12421 ccgtaatctc tagttctcca cgttctgaag gtttgatacc tttagcgata gaaattacct
    12481 cattgtcata aaaataaagg ccagttacag cgtaatttga ttttggctga gcaggctttt
    12541 cttcaatcga caaagcttgc atattctcat caaattctac tacaccaaag cgttctggat
    12601 cattgacatg atagccaaat actgtcgcgc ctgtatcttt tgaagctgct cgttgcaaca
    12661 ttttagacag accgccacca tagtaaatat tgtcccctaa taccaagcag acactatcat
    12721 ctccaataaa ttcttctcca atgataaacg cttgtgccaa tccatctgga ctttcttgta
    12781 ctgcatattc gatctgcagt cctaaatcat ttccgtttcc aaataattcc ttgaaacgtg
    12841 gtgtatcttg tggcgttgaa ataatcagaa tttctttgat tcccgccaac atcagagtag
    12901 acattggata ataaatcatt ggtttgtcat aaatcggcat caattgtttc gatgttgcct
    12961 ttgttaaagg gtacagacgt gttccgctgc ccccagcaag aatgattccc ttcatggata
    13021 tctgctctcc tttttgattt caaatttcac tttgttatta tctcatcaat tgttatattt
    13081 gtcatggaaa tattaaggat ttaaacatct tttatcaacg tttaaaccat tttcgtttga
    13141 tcaacgccgt aatcagatga acacgccaag aaattttttg ccgtaattta gaatgtgttt
    13201 caatctcact cgcgtttaaa tcatgtcttc ggtacagagt taacggttct cttaggaacc
    13261 cagtcttctt tcctcccagc aaaccaatcc acatatcatg catcggcact tctgacggga
    13321 tcggcaaaat atcgggtttt aaagaagacc ggaaagccat accagcacca atatagtgac
    13381 ttcttatcac attattaagc catccttctt tggaatttcg aaacgaaaaa tacgaatcat
    13441 ggatctcttg cagctcgctg tccacaatga ttaaatcaga aactactact agctgatccg
    13501 gattctgctc aaaatagtca gtgatctttt tcacttttgt ctccaaccaa acatcatctt
    13561 ggtctgccaa aaagattaga tctcctttcg tctgctggat cgcataacca aaattagcga
    13621 tcaatccttg acgaggcccc gaaaaaagct ggattcgctt atctttttct gcgtattcag
    13681 ttaatatatc ccatgtatca tctactgacc catcatcaga aatgactact tcatcttctg
    13741 ctgaaagctg agataaaata ctatctaact gctctcttaa atatctgcct ccattaaagg
    13801 tagctataca aaccgaacgc acgaattcac accttccaat tcttaacata tgagcgcaaa
    13861 gtcatccgcc agatatgccg gtttttgacg gtcaagaact gtttagctgt tcttaacaat
    13921 aattgtcgtc ggtgactgga taaatgcctt tgatcatatt catgataaaa tcgattttct
    13981 gcttgtaaaa tagaacggta tcgattactt gaaacttttt catagtctaa aaccgaaaga
    14041 tcatgttcca ttcgtacagg aaggatctcc acagtttttt ccaactgatc cactttccaa
    14101 aacagccaat gatccaaaaa atctaaagaa aaagcaggat taaacccgcc aatctttttt
    14161 agaaatttga cagaccaggc aacacctgaa ttgattgcca tgattcgttc agctgttggg
    14221 ccttcaactt ctactgcttg agctgtacga ttgatataac gatctgaata taggggagaa
    14281 acttgtcggc tcccagaaaa aatcatcgga actgcagcaa cacattcatc tgtaaaggtt
    14341 actttacgca atagttcaaa ataatcgtcg actagcctcg tatcctgatc cagagtgacg
    14401 agacaacgtg ttccttcatc tgcttgagac aacgcaaaat tataagccac cgctaaacca
    14461 ggattttgcg gatcatgatg ataaacgata ttttcttttt caaacagctc attttgctgc
    14521 ctttgaggac tattatcgta aataataagc tgaatttgct tttcgctaag tgctttgctt
    14581 aatggtccat aagctggaga ttgactgaat agttgctgat aaagcacaac gactactaat
    14641 atttctggtt tcatcagaaa aaacgccacc cccacttatt gaaaaatttc atcatagaag
    14701 tcaaaaacac gcgaaacagt tttgcatttc gatgcgcacc cttcccgtaa aaatggataa
    14761 ctgcataaaa gggtgtgtac aataacttgt aacctgcttt ttcaaaactc aaacacaagt
    14821 cgttgtcttc aaagtacatg aagaaacgct catcaaaccc ctttatctct ttaaatttat
    14881 caatatcagc taccataaaa ctacctgaga tcatccgtac ataactatta gcatcagtag
    14941 gcaatcctcg gcattcaaac acagccagtc gtttgtcaaa cttttttttg acccatttga
    15001 aaggcacaaa gcgcaaaacg taatcaaaaa cagccagctg ctcacggatg aggtgctgag
    15061 ttgttccatc ttcattaaga atcttaggtg ctaacatcgc acattccgga tgttctttca
    15121 ataacaagac caatgctgta actgtctctt catccactaa aatatctggg ttacaaataa
    15181 tgccatagcg agaatcgcta gctatcagat tgtgattatg tccataacca aatccggaat
    15241 tttcatcatg aaaatagata tcgatgtagg gatatttcct atactctgtt agtctttttt
    15301 tgtactcggg aagtgaattg ttgtcaaaaa ttcggatttt tactgctgtt tcatctttta
    15361 cagttgaaat aaaattatct agtgtccgaa aaattttatc actgtttgcc gtcacaatac
    15421 taataaggat cggctggttt aatttgttat tcatctatat gacggttcca tttcttcaaa
    15481 tatttctgtt ttacttgcgt acggtactct ttattcccta aaaatcgcaa tgtttttaaa
    15541 ataaactgat gtttctcatt gatcagacca atcaattcaa ataataaaat tgcagcaaac
    15601 aacatggcaa taatcaatat gatcgttccg attcttccag tataattcat gaccatagct
    15661 gtgaaagaaa acatcaaagc catcgcataa atcgtcagga cagcaccttt atgagtaaag
    15721 cctaaactga ttagtcggtg atgaagatgt tttttatctg ctgtagaaaa agaaacacgg
    15781 tttgcttttc tcctaatgat agcaaaaaac gtgtctgtta ccggcactcc catgacgatc
    15841 agcaaagaaa tcgatgaaac aaaagtcacg ttcttcagcc cttgtagtga aaggacggcc
    15901 atcataaacc ctaggaatag agctcctgta tcgcctaaat aaatctttgc cggataaaaa
    15961 ttgtaaggaa aaaaaccgat aatacttgct acaagacaga aaataacaac tggaatatac
    16021 actgtagaag catggaggaa aaaatatcca atgattccta tcgtaattaa accgatcaat
    16081 gaaatccctg ccgccagccc atccaaaccg tcaatcagat tgaccgcatt cgtgataccg
    16141 aagatccaaa aaatcgttac gggaaaacta agccagccta gttggatata tccaataaaa
    16201 ggaagcgtga aggaatcaat acgtatatct gctacaaaat aaataataag agaagcaatc
    16261 aagatcccta tacttttttg tttaggtgtc agctcatatt tatcatcgag cactcctgtg
    16321 actatgatta ctaaagaagc aatcaagatc ggtacaatat acgattgagg gataatttta
    16381 cggaataaga ataaagtcga tataacaaat gaaataaaga taggcagtcc gcccgctgaa
    16441 ggcattggaa ctttatttat tcttctttca tttggtttgt cgaccatacc tgtttgtact
    16501 gaaatgattt tgaatacagg tgttaatatc agtgataata aaattgtcag aaaaaatctt
    16561 ataaccatac taaaagaaac aagcatatgg gcacctactt taattaagag tcataattat
    16621 tataaattat atatgtcttt ttgactatct ttttatatct tctcaaatgt ccgcaaagcc
    16681 ttattttatc ggctctacgg gcattttgct tttgtggtaa acctcgcata tctaggtcta
    16741 tcttcttata ttttccctgt caatcgtggt taaaatcgtg gtaaatactt ctatgcgatt
    16801 agacgctgaa cctctgattt tgcggtatct atggacgcat gagcgtacca gttcattgtg
    16861 atactgatgt ttgaatgccc catgatatac tgtaaatctt tcgggttcat gttcttgctt
    16921 gccagccttg tgcagaatgt atggcgtagc gtatgcggtg taatatgtgg caagggattg
    16981 tccttgtggt gcttgttgta tttctttacc atacggataa ataaggcgtt ataatcaatg
    17041 gcaacttttg gattaccttt cggattgata aacacaaaac cgctgtgtcc gtctacctct
    17101 atcgacttta tctttggtcg gctgttgata acccgttgaa atgcctgtat cgtttctttg
    17161 cttaatggca cttgccttat cccgcttttc gtcttaggcg tttcaatata atagccctgt
    17221 tccttactct ttagtaactg gtggtcgata atcacaactt cattcttgaa atcaatgtcg
    17281 gctactgtca gtccgcacag ttccgagata cgaagtcctg tctttaacag tatcagcaca
    17341 tcatcataat gcttgtgata cacgttgtcc gtcttaataa atgacaataa ggcttgctcc
    17401 tgttcctctg tcaatgcgac tttctctttg gtatcatttt ctatgacttc acttagcttg
    17461 aaatcaaaag ggtttttcct cacataatca tcttgtatgg ctatgtagaa tgacgctttt
    17521 aacgagcgtt tatggttgtt aatggtattg taggaaaagc ctttgtcttt catgcgtaac
    17581 gcccattctt tagcgtcaga gggttttatc gtatcaatgc tcctagcacc taacttgtcc
    17641 tcttttaata accgcatgag ttgttcccgt tgtttctgtg tgcttttctt cacatttgtc
    17701 ctctgtgcgt tctgtttggc atagagttgg caaagcgtca ttttcttgcc tgtgctgtcg
    17761 ataccgtcct caatatcccg tcttatctgc tgttccagtt ctcgaagtga gggtttttcc
    17821 cgttttccct ttggtgtcgg gtctgtgggt gtcaatctcc aagcatacac atattttgtg
    17881 tttcccaatg cgtctacata tttatataag tattttccgt ctgttcgttg gctctctcca
    17941 gtatgcagga tacgaccttt gttatcccgt cttttttctt tcatggtgtc tgctcctttc
    18001 cttgttggaa agagccttga tatgacttgt gttcatcata acacatacaa ggctcatttg
    18061 cattagattg cgtccaattt atcaataacc ttttcaaact gtcggcgttt aatctgtatg
    18121 cggttgccat tcataatgag ccagccagcg tccttgtttt cctctgccaa tcgtcttaac
    18181 ttgttttctc caatgcggaa atactttgac gcttcttcaa tggtaagggt gtatttttcc
    18241 catacgggaa tatcctgtgt attactcata aaacaccccc tcactttcga ttacgtctga
    18301 tatgtccgta cacatctgtt ccacaagcat ttcctgtttt tcagaaaggt gggtacattc
    18361 atcaatcatt ttcatgtagt ttgaacctgt cagcctgtcg atttcctcta tcatcacgat
    18421 tgacggcatg acctgtcttt ccagccattg cagagtgcgt tccatattga caggtacagg
    18481 gttcatttca aaaggtaaac tgtcatggga aatgaatatc tcccacaatg gatagtcagg
    18541 aaattccaca aaatcggtaa tgagataaaa caccagccca tgagggttat acgtcaataa
    18601 cagttcttca actgcctgta ccgccttttt gtcacgcaga cgaatttcaa aacggttgat
    18661 aatatcggta tgtttctttt tcgttgcctg ttccttttgt ttttcataca ggcagaaata
    18721 ttttgtgctt gcctttgagc cgatataaag ggtacttgct aaattacggt tttttccgct
    18781 taattttcca ccttgtacat tttcatagtt tttacagcga cattccgcac caccatttct
    18841 gtatttttca gatagcacag gaatatccag cagaccgcac atatcattga ttgccaagtc
    18901 aaaacgtcgg ataacaccgc cacagtcaag acagcggttt aagaatgaat accagtccct
    18961 gttctgtgcc tgtaagacat attccatgtt gcgtgagcct gcccctttta attctaaaaa
    19021 tacgcccatg tgttcatcat cagaagccat gaccttgatt tccccgtaag cataatgctc
    19081 cttatagcca taatacccat agtcataatg gataaaataa tctgctttca tgccaagcac
    19141 ctttcggata acttccaatg cgtcagtcgt tggaaaacgg acagacagat aatcaacgag
    19201 cagataaaaa ggcttatcgc agatatagta attcagacaa cgcaggataa tgttctgtgt
    19261 ttccttgctg gcgttagctt ttccgttctc aaagcggttg atactatatc ttgatacatg
    19321 ggtaagactt gcaagttctc cttgtgaaag accgctggca agacgtttgt tcttcatttc
    19381 aagtgcaaat tctaaattgt tcattgtatt cctccaatcc cacaatagcc ttgaaatacc
    19441 tgtaaaccac ctttcaaaaa gtgtgatatg tactatcttc ttaaaacctc tcattactac
    19501 tcacaggttt gggggtgtat ggtttttgac ttgtcttttg tgaaatagtg cccccctgtt
    19561 agataacggg ggcacagaca aggctcgcag gctcgccagc cgacaaagca tttcttcccc
    19621 ttgacacaag gtgtcatggc ggtaagcctg agaggcttcc gccaccgtgt cagaaatact
    19681 ttgtcagcaa gttctgtttt gccttttcta acaagttcca tttcaaccga tattcatatc
    19741 tacggattta atcagatagg tatttctttt tgaatgtttt tatatttcat tctattgtgc
    19801 ttattcgatt acaagaacat agtaattctt atatgcttat ttgtcaatat ctttttttgc
    19861 ctttacaaat catattaagc atgatagact tataatagcg aagatataac gagatatgga
    19921 gggttatgca atgaaaataa gccatttagg aaataatata cagaccataa gaaaatttag
    19981 gggaatgaaa caacaggaac ttgcggacaa aatcggtatc aatatgcaga gcctttccaa
    20041 gattgaaaga gggttgaact atcctgccta tgaaacgctg gaaaagataa tggaagtgct
    20101 ggacgttacg cccaatgaat tgttgtcggg agaatggaag tatgtcaatc aatctgaaaa
    20161 ggaagtctgt cagtttttaa gagccgaaga acgtctaaat gcagaactga aacatggaca
    20221 ctatgataac ttctttgaca gcgaggaaga atggctggaa tatgagttag aaaagttacg
    20281 ggaatatatt acagactata tcaacgggaa aagcattgaa gcgtccgacc tttacccaat
    20341 caaagaattt atccagcatt tgaagtttca aaaattatta gaccgctatg atgatttata
    20401 cagtatggat atgtttgggg aaagcataga gggacataag tataagacac cttatcaagt
    20461 cgtgaaaatg ataaacccga actcaaaaga agatatggaa ctgttacgag aagtattaag
    20521 gaataacaat tttgatgatg aggacgagta acttttttcc tcttgcgaga agatacagca
    20581 aacaaaaagc ccgatcaaga gtgcaaagca ccaccaatgg tggcaaagct cttgacaggg
    20641 ctttttcttt tctgttgtgg gcaatcaaga ggaagaaagg gataaaatct gatttgtggt
    20701 aaatcaggca aaggcaacgc aggtatcaca gtatgaattg acaccgcata aggaaagcaa
    20761 ctggaagatt gtagaataaa tgaaaaaggc ttgcattctg catttttata aaattgcaag
    20821 tctttatatt gacaagcata aaatactaag atatacttta atcagaccaa cggtttgtat
    20881 tggaggtaag ttatggcacg aaataaatat ccagaagaaa cagtaaaact cattttagat
    20941 gtttctacaa aaatgttttg tgaaaaagga tatgataaca catcattgca agatattatc
    21001 aatgaaacaa aactttctaa aggtgctatt tatcatcatt tcgattcaaa ggaagatatt
    21061 ttaaaagcaa tttttcaaag aattggaaat gaaaatgcag taatatttgc taaaattaga
    21121 gataacgata gtttaaacgg tttagaaaag ttaagagaaa tatttaagac agcggtattc
    21181 aattctaacc aaagcgtttt attgacagtt tctcctcaac tattaaacaa tcctcgtttt
    21241 cttgctatgc aaatagaaca aatgtatgaa attgtagtac ctgaatttgt tgaacccgtt
    21301 ttagaacaag gtatcaagga taagtctttg gagattgaaa attcacatga aattgcagaa
    21361 gttatcatgg tattaagtaa tgtatggctc aacccattag ttgaaatgac ggataaagag
    21421 ggtatggaaa aacgttgcaa tacattcaat gcccttttaa atggaatagg catagacaca
    21481 ttattagacg aagaaacaat ttctgcattt atacagtttt gtaaataact gtatttgtta
    21541 tccctatacg atagactgct ctataaaaga gcagtttatt taaaccatta tataaaccga
    21601 cggtctgttt gattaaataa aaaggagaga ttttatgcaa gcagaaaaaa aactttttaa
    21661 tcgtgatttt atacttgttg ttataggaca gataatttct ttatttggaa acgctatcct
    21721 acgatttgca ttaccgtact atttgttaaa agaaactggt tcatcagctt tgtttggtat
    21781 tgctacagcc tgctcttttt tacctatggt tattttgtcg ctggtaggtg gtattattgc
    21841 tgacaggaca aataaaagaa acattatggt catactagat tttgtaacag caatcataat
    21901 tttagtattt tatttgtcat tgggaaaaat tcctatcata cctttgttta ttgttgcttt
    21961 gatgttactt tatggtattt ctggtgcata tcaaccagcg gtacaagcaa gtattcctct
    22021 attggtatca tcagataaac ttaccgtcgg taatgctata ataaatcaag taaatacttt
    22081 agcaaacttt atcggaccag ctataagcgg agtagttttt caattttatg gtatcaatcc
    22141 cattttaatt gttagtatta tatgttttac tttttcagcc attatggaaa tttttatcca
    22201 tattccacac caaaaaagac ctcgtgaagt aggtgtaatt gcagttgcta aaaacgattt
    22261 aaaagatagt tatacctttt tgaaaaagga gaaacccatt tttatatccg taatcttttt
    22321 ggtttgcatt ttcaatttgg ttttaagtgc tgttttaatt gttggtctgc ctatcttaat
    22381 ttctgaagtt ttaaaaatgc cagatacact atatggtttt tcacaatcag cattatcatt
    22441 aggtggttta tgtggtggta ttttaacagc tcttgttgct tcaaagttaa aactaaaaaa
    22501 cctttatacc ttgttactta tttgttctgt ttctgtttta cttatgggaa tttcgctatt
    22561 tttagaattg cctgcaatag tttcctactg ggtagttaca gtgatgtgct ttgtggctat
    22621 gggtgtatct actatgtttg ttgttcaaat ttacactctt gttcagacac aaacaccacc
    22681 gcaattagta ggaaagataa tggctacgct ggtagcagtt gctatgtgcg gtcaacctat
    22741 tggacaaatg gtttacggta ttttattcga tgtatttata caagaaacat gggttgttat
    22801 gtttgtagct tctattgctt caatcatgat ttcaatatat tcaaaaagaa tttttcaaaa
    22861 gttagagata taatacaagg ggttaaatag tatgttaggc taaaaacaat atataaaaga
    22921 aaatttgaaa tctgctaaaa ggatagtgtt ataaaagaaa gagtaatatt gcagtattta
    22981 aggctcgcac aaatatatgt tttgtgtggg cttttttctt accatttttc tgtatttcta
    23041 aagggtataa acggtattcc gtttatatat ttcagcatta gcagaaaggg ggtgagatta
    23101 tgaggacatc ttctttcgag catatcgtca gattacagtt caattcttta atgctgattg
    23161 tcattaagaa caaagtgaaa agtcgaaaca gacagcttgc aagacattct aaacgtgaag
    23221 tattgttttg tgaaatagcc gaaacgaaac aagttgaacg tggaacgatt gatacctgtt
    23281 tttatgattg tgtatcattt aaagtcttgc actttacaat ttatgtatct gatgaaacac
    23341 ttggtacagt tttacataga ctgtcagaaa aacagcgtag tgcgatttta ttacgttatt
    23401 ttcaaggaat gaacgacaga gaaatttcag aactgtacca tgtatcacgt tctgctattt
    23461 gcagtagaag aactagagga ctaaggaagt taaaaatgct tttgagcgaa aggaagtaaa
    23521 gaaatgagta aagattatgg ctatccctct tttgaattga tttgcaaagc gtcaagcgga
    23581 gatgaaatgg cagttaaaga gattttgaag ttttatgacg gttatatttc taaattatgc
    23641 ttgcgtcctt tttaccactc tgaaagtggt aaaatcatta tgcaggttga tgaagaacta
    23701 aaaggagaaa ttcatacaga catgatgaaa gcaatattga aatttgaaat cggagtgaag
    23761 taatcaactg tataaaaaaa tcgggagata cacagtttcg tgctatctcc cttagtagtt
    23821 ttacggtcat atcaaggctc attcaatcgt ggtaaattcg tggtaagatg agtgtttttc
    23881 tatacttcaa aatgcttgaa tgtatagtgt ttatgcggat aattgaaaat tagatataaa
    23941 atttcaaata aattactgat ataaatttac aataagaact cttgtttcta ctttttttta
    24001 tgagaaaatt tagttttcaa tttattgaac cattttcggc ttggatctcg acgttttttg
    24061 atttgatgac ccgtcacgta ttcttgaaca actgcattga tgattccgcc caaaatgatg
    24121 atcgtagcag caaaattaag ccaaagcatg agtacaataa aacttcctat gatctgataa
    24181 ccgctgatcc tcgttgcaaa atacctagca tagatactaa acacttgtga taacagcatc
    24241 cagccgacag tagcgaagat cgtgcccgga atgatcgtct tcaacttcaa ctgagcatta
    24301 gggacaatta aataaatcaa gaacatgatg acaaataaag ctaccaatgt gattggccac
    24361 ttcaaagttt ggaactgatc gataaagttc acgggtattt gtacgattgg ctgaatagca
    24421 tccaaaatca gctgtcccaa cccaagaacg atagttaccc cactaatagc aatcatgaac
    24481 aagacaatga caattagtga gaagaaacgg acgatcaaaa aattttttct attttctacg
    24541 ccatacgctt tattcatcgc aatttgcaaa gcattgatac tttgacttgc agaccataaa
    24601 gccgctaatg cagaaacgga taacaagcct cctgaacttt gtgtcaaaag gtctttgatt
    24661 gcaggaccga taaactggta aacggtctca ggaatcactt ctcgtaaata ggtcagtaca
    24721 gtctcttgat cgatgtggag aaacggtaaa atattaccaa aagcaataat caatggaaat
    24781 aaagacaaga gtaaataata agcaacgacg acagaggtcg tactcatttc tgaatcagtg
    24841 atgcgctttt gagtcgtctc aataaagcgc atcagatttt cattttgttt tattttgttc
    24901 caaactttca tgtacctctc ccgtacctat tgactggata gatcaataag tgccttcttc
    24961 tccttgtgat gtcaaaattc ttggaccatc tttagtaata gccaatgtat gttcatattg
    25021 gcaagaaagt ccgccgtctc ttgtatacgc agtccagccg ttaggatcca ttttcatttt
    25081 ccaagttccg gtattaacca taggttcgat cgtgataacc atgccttctt tcaaccgcaa
    25141 cccttttcca gcttctccgt aatgaggaac tgctggttct tcatgaatcg taggaccaac
    25201 gccatgacca ataaaatcac gaacgatcgc tagattttcg ccttctacat aagtttggat
    25261 agcatgaccg atgtcaccaa tccgattccc tacttgtgct tgctcaatac cgatgtacaa
    25321 agctttcttc gttacttcca tcaatcggtc gatctcaggt gtagattctc caactacata
    25381 ggcccaacaa gaatcagaaa tgccgccttt caaatcgata cacatatcga cttttaccaa
    25441 atcaccgttt ttcaaaggct ttttacgagg gaatccatga caaatttcat catttatact
    25501 gatacaagtc gcatattcat acccttcaaa gccaatttgc gcagcaattc cgccatgact
    25561 ctcgatatag tttctgacaa atacctcaat atcccaactt gtgattcctg gttttataaa
    25621 atcacgcaga tttttatgta catctgctaa taaagctcca gattctgcca tcatttcaat
    25681 ttcacgtgct gattttaaag taatcatatt ttcgtctcct ttttacaaat ccctctcatt
    25741 ttaacatagc ggcatacatt tagccaaatg acattcccca ggtgtctcta ggttttattt
    25801 tcttttcaat gatgttttgg tataattcat aattgttaaa taattataaa cgaggaggca
    25861 catcatggct ttagcaaaaa tcgtatatgc tagcatgaca ggaaacactg aagaaatcgc
    25921 cgatattgtt gcagaagcat ttgaaaatct ggatatcgaa gtcgaaatca acgaatgtac
    25981 ccaagtagat gcagatgaat tcgaggaggc agatatttgc gtagtagcta cttatacata
    26041 cgatgatggc gatctgcctg atgagatcgt agacttttat gaagacttgc aagaattgga
    26101 tctattggga aaaatttacg gtgtctgcgg atctggtgat actttttacg atgaattctg
    26161 caaatcggtg gatgatttcg atgctgcttt tgcaaaaaca ggcgcatcaa aaggagccga
    26221 aaatgttaaa gtggatctga atgctgaaga agaagatatc gaaaatttag aagctttcgc
    26281 taaagaacta gtcgcaaaaa tttaatatac ttgcaataaa agagccat
//
LOCUS       DBBGSZ010000168        19535 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.guided.043, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000168 DBBGSZ010000000
VERSION     DBBGSZ010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19535
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.guided.043"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(<1..685)
                     /locus_tag="ACIZE5_002927"
     CDS             complement(<1..685)
                     /locus_tag="ACIZE5_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HGC6109982.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDP"
     gene            954..1850
                     /locus_tag="ACIZE5_002928"
     CDS             954..1850
                     /locus_tag="ACIZE5_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HGC6109983.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(2000..2941)
                     /locus_tag="ACIZE5_002929"
     CDS             complement(2000..2941)
                     /locus_tag="ACIZE5_002929"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HGC6109984.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            3067..4188
                     /locus_tag="ACIZE5_002930"
     CDS             3067..4188
                     /locus_tag="ACIZE5_002930"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HGC6109985.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            4446..5948
                     /gene="eat(A)"
                     /locus_tag="ACIZE5_002931"
     CDS             4446..5948
                     /gene="eat(A)"
                     /locus_tag="ACIZE5_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HGC6109986.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            6015..6542
                     /locus_tag="ACIZE5_002932"
     CDS             6015..6542
                     /locus_tag="ACIZE5_002932"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGC6109987.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            6753..7814
                     /locus_tag="ACIZE5_002933"
     CDS             6753..7814
                     /locus_tag="ACIZE5_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HGC6109988.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            7817..8713
                     /gene="murQ"
                     /locus_tag="ACIZE5_002934"
     CDS             7817..8713
                     /gene="murQ"
                     /locus_tag="ACIZE5_002934"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HGC6109989.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            8727..10709
                     /locus_tag="ACIZE5_002935"
     CDS             8727..10709
                     /locus_tag="ACIZE5_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HGC6109990.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(10774..11220)
                     /gene="nrdI"
                     /locus_tag="ACIZE5_002936"
     CDS             complement(10774..11220)
                     /gene="nrdI"
                     /locus_tag="ACIZE5_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HGC6109991.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            11431..12855
                     /locus_tag="ACIZE5_002937"
     CDS             11431..12855
                     /locus_tag="ACIZE5_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HGC6109992.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(13036..13809)
                     /locus_tag="ACIZE5_002938"
     CDS             complement(13036..13809)
                     /locus_tag="ACIZE5_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGC6109993.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(13806..14711)
                     /locus_tag="ACIZE5_002939"
     CDS             complement(13806..14711)
                     /locus_tag="ACIZE5_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6109994.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(14865..15185)
                     /locus_tag="ACIZE5_002940"
     CDS             complement(14865..15185)
                     /locus_tag="ACIZE5_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HGC6109995.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            15659..16345
                     /locus_tag="ACIZE5_002941"
     CDS             15659..16345
                     /locus_tag="ACIZE5_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HGC6109996.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            16347..17291
                     /locus_tag="ACIZE5_002942"
     CDS             16347..17291
                     /locus_tag="ACIZE5_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HGC6109997.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            17490..18134
                     /gene="pcp"
                     /locus_tag="ACIZE5_002943"
     CDS             17490..18134
                     /gene="pcp"
                     /locus_tag="ACIZE5_002943"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGC6109998.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            18213..19490
                     /locus_tag="ACIZE5_002944"
     CDS             18213..19490
                     /locus_tag="ACIZE5_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6109999.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
BASE COUNT         6298 a         3482 c         4125 g         5630 t
ORIGIN      
        1 taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg taagaataga
       61 taactacaag caaagaactg atgattccct tcataccatg aggagtaaac ccaccatggt
      121 cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga ccgacaagat
      181 aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc agccaatatt
      241 ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa acagccaaca
      301 taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag gaagcagctg
      361 caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa tcagtaaaat
      421 cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga tgcgtgtcgc
      481 caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc agcccaccaa
      541 tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca cttcctttaa
      601 atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg gagctaagtt
      661 gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca caatcaaaat
      721 ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat tttcagacaa
      781 ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt atttcatcat
      841 attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact ggctttttac
      901 tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa aagatgaaca
      961 aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct tccatccgct
     1021 ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa tcagctagac
     1081 aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat atggagatgg
     1141 ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg aatcacttca
     1201 aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc gatgagattt
     1261 atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt tcattttatt
     1321 cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt ggtgcaacga
     1381 ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa agagatgtta
     1441 cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat cttacttatg
     1501 aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg cgggagggtc
     1561 agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa ctagtgacgg
     1621 ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt ttgcttcgag
     1681 aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca atcctatcag
     1741 agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact aacgattcca
     1801 ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa aaaacctaca
     1861 ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc atgagagttg
     1921 tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct gattcagctg
     1981 attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca tggactaatt
     2041 gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt cgccaaatgg
     2101 caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct tggtacatag
     2161 atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt tggtacactt
     2221 cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca gatacgattg
     2281 ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta caatccaaaa
     2341 tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg gaataacgaa
     2401 cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca actttttttg
     2461 taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca cctaacaatg
     2521 tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat aagatatttt
     2581 tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt aaacacaaaa
     2641 cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct aattgattgg
     2701 cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt tcttctggtg
     2761 aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc aacccatttg
     2821 tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca tttccgcttt
     2881 gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt gcgattttca
     2941 tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa tggaagaaaa
     3001 tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag aaagtgaggg
     3061 atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc ttcatttgaa
     3121 ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat caatgtgccg
     3181 attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag gggaacatgg
     3241 cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta tttattgaca
     3301 acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg gttagatcta
     3361 cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt aggagaactt
     3421 attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg aggaagcggg
     3481 tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga agggtacaca
     3541 gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa cgttcttgtt
     3601 tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg tcaacaagga
     3661 gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc tttcttagat
     3721 aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga tttagatgat
     3781 attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt gggagcgaag
     3841 atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa gatcgaacaa
     3901 gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca cggaaaagtt
     3961 ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc tatttgcgga
     4021 agtagagacc aagagctaga aggactttct gattttctcc caattgtctt aagtattcat
     4081 ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga aaaaacaaaa
     4141 atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt gacaaaatca
     4201 ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg tgcattgaaa
     4261 aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca aggaagcagt
     4321 gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg tgtgtatcca
     4381 acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt acgaggtgat
     4441 ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc caaggcacat
     4501 tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga cttatcggac
     4561 gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta ccttatcaag
     4621 ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa gataaagaac
     4681 gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa atcgaaagag
     4741 agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc acactatcgg
     4801 ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact catttcccgt
     4861 taatcgatga accaacgaat catttggata tctctggtag aaaacaagta gcggcttatt
     4921 tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt atcgatgaag
     4981 tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa gggaatttct
     5041 ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa aatgaaaaat
     5101 tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa tggtctcgtt
     5161 cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa tctagacgag
     5221 tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc aaagcaatcg
     5281 tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat atcgaatata
     5341 tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta agcgtagaag
     5401 atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca atcgagcctc
     5461 atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt atccattatc
     5521 ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa catctgagca
     5581 ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa tttgcagaga
     5641 aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg atggaaagag
     5701 atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa gtggaattgg
     5761 ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg aattatttgg
     5821 atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct gccatgttac
     5881 tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt tctcttgaga
     5941 gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac tttgccaacg
     6001 aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg aacgcacaag
     6061 gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg caggcacaga
     6121 aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc cattcccctc
     6181 ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg ccgctgaccg
     6241 ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca agcaaagatg
     6301 agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg gagtcagtct
     6361 tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac gaagaaaatg
     6421 tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat tttcatccga
     6481 tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt tcttatgagt
     6541 aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg cttagcagtg
     6601 ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag aaatgaaatt
     6661 taattatttt aataaaagta ttgaaatttt gtttctttag atatatactc tagtcataga
     6721 aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata tttatgaacg
     6781 attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat ggctttgtcg
     6841 gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa aagcgattga
     6901 tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat atttcaggag
     6961 aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa gcaattggtg
     7021 taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac tggtcacatc
     7081 aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat gaattgaaag
     7141 aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca cgtcccgaaa
     7201 cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt caaggtctcc
     7261 ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat caaggattgc
     7321 caactttgga agaacatcga gggatccatc ctcttgcagg cgctctagat ctattagcaa
     7381 gtaacacgga tattgtttac atcggagatg caggtctgtc agaaaacgtt caggagcaat
     7441 ttgcttcttt ccaaaaagaa cagacagtct tgctccatac ggaacctgta gatgaagaat
     7501 tttacgaata tatattaggg aagcatacga atcggcaaga cgatgcaaga gatgtcatac
     7561 gaagcgtaga tgcacgtttt cgagagattc cgcctatccc agcaagaaat acagctacgc
     7621 gtatgaaagg gtctattact ttagataacg aaaagtattt gcgctatatg ggtgagatcc
     7681 aattaaccaa atatgatttg ccagcggatg aaaaagtgaa tgtagtagct aaagttatca
     7741 aagaagagct accattgatc aaccaaatca aagctggtat gaactatcaa tttataagaa
     7801 aagaaggaag ataaaaatga gcaaaatcaa tttagagaac ctaacaacgg aacgcagaaa
     7861 ccaagaaact tttggattag atgagatgag tatttctcaa gccgttcaac taatgaacaa
     7921 agaagatcag aaagtggccg ctgcggttga aaaagaactg acaagtatcg aaccagtgat
     7981 tgctaacacg attgagtcct ttaaaaaagg tggacgtctg atttatatgg gagccggaac
     8041 aagtggaaga ctaggtgtgt tagatgctgc tgaatgcgta ccgacattcg gtgtagaacc
     8101 ggaaatggtc ataggtctaa ttgctggtgg agaagaagca atgactgtag ctgtcgaagg
     8161 ggccgaagat tcttatgagc tagggcaaga agatctaatc aagctgaatt tgacaaaaaa
     8221 tgatatagtt attggtatcg cagctagcgg tcgtacacca tatgtgatcg gtggattaga
     8281 ttacgcaaaa tcgatcggtg ctgtcacagg aacgatttct tgcaataaac aagccgaaat
     8341 cagtaaacac gcggatttcc caatcgaagt cgatgcaggt ccagaatttt tgacaggctc
     8401 tactcgattg aagtcaggaa cagcacaaaa acttatcttg aatatgattt ctactatcag
     8461 tatgattggt ataggtaaag tattcaataa cttgatggtc gatgtcaaac caacaaatga
     8521 aaaactaatc gaacgctcaa aacgaatcat catgcaagcg acagaagctg attacgaaac
     8581 agctgaaaag tactttgaag aagcagatca aaatgttaag ctggctatcg tcatgatttt
     8641 gacaaatagt gataaagagg aagctcaagc aaaattagct gaagcaaacg gatttgtaaa
     8701 agggacctta tgagggggaa aagaccatgg caaaaaacga actgactttg gaagaactgg
     8761 caaaacaaat ttataaaggg gcaggcggca tgggcaatgt agaaagcatt gtccactgca
     8821 tgactcgtgt gcgtatgaag atcatcaatg atgatcttgt aaatgtctct gaattaaaag
     8881 cgattccagg agtgcttggt gtagtagaag atgaacagct tcaagtcatc atcggacctg
     8941 ggaaagtgaa caaagtagca cagcaaatgg ttgatttggc aggcgtgaaa ttaggagaaa
     9001 aactttcttc tgtaagtaca gctacagcaa attcatcagc atctggaaaa gaccgtgtaa
     9061 acgaacgggc acaagaaatg aaagcggcac aaaaatcgaa acaaaaacca tctaaaatca
     9121 aatcggtatt aaaagacatt tctaatatct ttgtgccaat gattcctgca tttgtcggta
     9181 ctgggatcgt ggcagggatt gccgcagttt tagcaaactt agtcacagcc ggaacacttg
     9241 atgcagcaac atggcaacaa tatatcgatg tgatgaacat cttgaaaaac gggatgttta
     9301 gctacctagt tatctataca ggtatcaatg ctgcacaagt ttttggtgca acaccaactc
     9361 ttggtggagt tatcggggcc gttgtgatgc tgacagggat gaatccggaa gcaccactga
     9421 aaaacttatt tactggtgaa gctcttgcag ctggacaagg tgggatccta ggtgtcatct
     9481 tcgctgtttg gctattgtca atcgttgaga aaaaactgca taaagtagta cctgatgcgg
     9541 tagatatcat cgttacacca actctttcat tgattgccat cggtctgatt gaaattttct
     9601 tcatcatgcc tttagcaggt ttcatttctg atggcatggt cggtgggatc aactgggtac
     9661 ttggcgttgg tggagcattt gccggcttcg ttctaggcac attattcttg ccgatggtta
     9721 tgttcggact gcatcaaatt ttgactccaa tccatgtgca aatgattgat gaaactggtc
     9781 gtacgctatt gcttccaatt cttgcgatgg ctggtgcagg acaagtgggt gcagcattgg
     9841 cattatggat tcgctgcaaa aaagataaag aattaacaga aatgatcaaa ggagctttac
     9901 cagtcgggat cctaggaatc ggcgaaccat tgatttacgg agtaacatta cctctaggac
     9961 gcccatttat tactgcttgt atcggtggag gtatcggcgg ggcagtgatc ggaatgatcg
    10021 gaaatgtcgg ggctatcgct attggacctt caggagccgc tttgatccca ttgatctctg
    10081 acggtaaatg gttaggctac atccttggat tattggcagc ttatgctggt ggcttcgttg
    10141 ctacattctt cttcggtatt cctaaagacc gtttagaaaa agaagaatta gcgactgaaa
    10201 cagccacagt aaatgaagtg cctgaaaaag tagtacctca aacttcagct gaaagtgtga
    10261 ctatcctctc atcagttgct gacggaacag ttgtttcttt agataaagca agtgatccag
    10321 tttttgcaca aaagatgatg ggtgaaggct actttgtaga accagaaaac ggacatatct
    10381 attctccagt tactggggta gtcagctctg tcttcccaac gaaacacgct attgggatca
    10441 caacgccaaa tggtttagaa atcttgcttc atatgggaat caacacagtt gacttaggcg
    10501 gtacgccatt tgatgtgaaa gtaacagaag ggcagcaagt gacacctgat acgcttgtag
    10561 cagaagctga cttagaagcg atcaaagcag caggcaaaga aacatccatg atcgtcttgg
    10621 taaccaatat ggatcgtgta aaaaactttg tcttggaaaa aacaggtaaa gcaaaagcaa
    10681 aagcacctgt gatggatgtc aaagcttaat atgatagaaa caatagaaac gaaagaagaa
    10741 actgaaatct atttttcagc ttcttctttt ttattattta ttgttttctg ctaaaatctg
    10801 ataaattcgt gtcacatcag atggtgttcc ccgtaattca taatctgcca agaaaggaaa
    10861 gccaaatgtt tgtgcatatt gtttggctgt tagacaatac tgattattga agtttttatt
    10921 tccgctaccg actacaccaa gacaaagttt atgattgtct tcatgttcca gatattcacg
    10981 catcgtttcg gtcaagattt ctgtatcacc gttatctaaa ccatttccgc cgtctaaata
    11041 agtaggaacg aaagtaaaaa atggttctgt ttctttcgta aaatcactat tttcatggat
    11101 ttcttttaaa gtaacttcag gattgacagg atcttctgca tgcatttttt cagcatattc
    11161 tgctagatgt ttggcaaagg cacgcgtatt tcctgaaatc gatatatata aaatgttcat
    11221 ggatcatcct ccaattcttt ccttttagta tagcatcttt tttaagtttt ttggtggtgt
    11281 aatttggaaa gggactaggc gctttgcttg tataatgaga aaaaagccgg tagaattata
    11341 tttctattaa agtttttatt aattaagtaa aaataaaaaa ggtttgttat actttttgat
    11401 aaaagcggtt ttattttgga ggatgcttac atggatacag agcaacagaa aaaaggaatt
    11461 ggtttaattc cacttgctgc cttagtaatt ggttcagcga ttggaggtgg cgtatttggt
    11521 attatgacgg acatctccgg atcggctggc ggcccagcta ttttcagttg ggtactcgta
    11581 ggaacagcaa tgttgatgct ctccttgtcg atcaataata tcaataaaaa acgtccagat
    11641 ttaaaaggcg ggatctttag ttacgcagaa gaaggttttg gccgtttcgc tggttttatc
    11701 agcggttggg gttactggct cacatgctgg ttaggcaacg tagcttttgc aacattgttg
    11761 atgagcgcat taggatattt cttcccagta tttgaaggtg ggcaaaatct ggcatcgatc
    11821 gtgatgagta cagtcttttt atggggatat gcatggctag tgaatcgggg agtcgaaaat
    11881 gctagtttcg tcaatgctat cgtcacattc tgtaaattag tgccattatt tttatttatt
    11941 gtagtagcta tcagcacgtt ttcgatccaa caattcattg ataacttttc tagcgacatt
    12001 atattgaatg cgaatggaca gccgatcccg ttttccagtc aagtattgag ttgcatcatg
    12061 gtgatgcttt gggtatttgt tggtattgaa ggagcctctg tcgtaggttc acgagcaaaa
    12121 aaacaatcag atgttgggaa agcaacgatt ctagggatat tcggcttgat tattatttac
    12181 gtcttggttt ccatgcttcc atatgggaca atgacgatga atcagctgca aacgatcaag
    12241 gcgcagcctg ctatgggcta tgtgtttgaa atgatggttg gtaaatgggg agcagtcgtg
    12301 atcaacggcg gtttgatcat ttctttagtt ggtgtttggc tctcatggac gatcttaccg
    12361 attgaaacaa tgggaaacat ggctgaagac ggacttttgc ctaaagcatg gggaaaactc
    12421 aacaaaaatg gggcaccaac ttatgctatc gtattgacga cgttatgtac gaatgtcttt
    12481 ttactttcat tattattcac tgacagtgct tataactttg cttacacact tggtacagca
    12541 gctattttct tcacgtggct tttcttagga ttgtaccaaa tgaaactttc ttatcagcgg
    12601 aaagaatggg tccaattttt agtagggctt ttagcaagtg cctttcaagt atgggctatg
    12661 ctagtcgtag cctttaatga agtaatgctt gttcttgttc ttttcttgcc aggcatttat
    12721 ttttacctca aagcacgtaa ggagcaaaac gagcctgtac aacatatcca cttagataag
    12781 attttactta taggtgtgac gatggtcgga gtgattgcaa tggttttatt tgccactggg
    12841 atgcttcacg tatagaagta taaaagaagt ataaagagag gttgtgagcc tgtcgtttat
    12901 tcaaaaacat actaggaaag gagctgtgac acaaatgttg tcacagctcc tttttcagaa
    12961 taaacggtgt ttaagagaca gccaatcggc aataaggctg aacgtctctt tcacagcctc
    13021 ttttttgatg agtcatcata cattttttcg cttaaatacg agatatccta atgctaagaa
    13081 caaaacgatg taagctaaat taccgaatag catttgatta gtagaaagat gagtcaattg
    13141 cttcatgatc tcttcgtttc caatttggtt ttgcagattc aacatactga tcggattcca
    13201 tttgatccac tcccattttt ggatgagtgc aataaggata ccagatatga ttgacgaagc
    13261 aaaataaaag acgattcctg ctgagatgga tgcgccggaa ctattgataa agcaagcaat
    13321 catcaacact aaacttaaaa tcagccataa accgatataa ctacccaaag tataagtgaa
    13381 caagctttgg atcagtgttt gaccagtaga aaccttctcc gtgaaggaaa tcgaagggaa
    13441 aagaatcagt ttcatcaaca cagtgacaat aatagctaaa aggtataaat aaacagaata
    13501 aataactaat gtgatccatt tgcttactaa tatttctcct cgagaatact ttcgataaag
    13561 gagatttttc aatgtaccat attgtgcttc catcgaaatg atcgtgcttg cagctgcaat
    13621 catgataaag acaatccaag atgtggcact aaaaagctga gcagtcattt caactggatc
    13681 aatgatcgtc gtgtattttt tggctagaag tgctgttcct atgagcaaaa caactaatag
    13741 aacagataaa acagcagttg actttttctt gatcaattta aataattctt gttttacaag
    13801 caatgtcatt tttcttcttc cccctttact gaatccagaa tttccaatag agaagattcc
    13861 aaatcattcg tcagatgctg gacgtctgtc acatggatat tttgtgcaga caatagctgg
    13921 atcacggttc ctaataattc ttcgttttct tttaaaagct tgattttatc aggatcttcc
    13981 aaagtatatc cagcttctgt caagatcgtt cgagcagcta gatcatttgt tgtagagata
    14041 acgatgaaat cttgcgctgt ttggttcaat tcagccattg tacattgttt gatgatcttt
    14101 ccttgattga tcaggatcag ctcatcgacc attttttcaa gctcgctgag taagtgactg
    14161 gagatcaaga aagaggtgcc ctgagtagcc aagtcggtaa tgatttttcg cacatctctt
    14221 gttgcttgtg gatccaaacc gttcatcggc tcatctaaaa taacgataga cggatggttc
    14281 agtaaggcaa gagcaattcc caatttttgt ttcattccca acgagtagga tttcgctttt
    14341 ttgtgaatgt acttttccat cttgagctga ttcacgatag tgtcgatagc agatacatcg
    14401 ttggtttcag agaataactt cagatgatca tagcctgtta agaatggata gatacccggg
    14461 tattcgatca atgctcctac ttgttccaac cctttatgac tagagggaga aatctcattt
    14521 tcaccaatac agattgttcc atctgagtaa tggatcagtc ctaaaatagc tttcatgatc
    14581 gttgtttttc cagcgccatt aggacctact aatccaacga ttttgccagg ggataagcta
    14641 aaactgacat cgctgagggc ttgtttgtga ccaaagttct tggataattc ttggaccgaa
    14701 agacttttca aaaatattca ctccttttct atagatagta caagcataca cctgatgagt
    14761 ggagaagtcg ctaggtcatt ggacttattt cttatttttt cataaaaaaa ttgaatatta
    14821 aataaaaagg cttatttttt ctgatcagta cttattccaa gtgtctagtg gccgctagta
    14881 atcttgatgc caatgatact gatgagtagc atccccacaa agaaccaagt ggaaagattc
    14941 agcttatcat gaaacaagac cacaccaatt atgaccgaac caactgcgcc aatccctgtc
    15001 cagataggat aagagagact catcggcaaa cttttgattg cctttgacaa aaagtaaaaa
    15061 ctagcaatca tgccaatcac tgtgtaaaaa gaataattga ttttagaaaa accatcactc
    15121 catttcatca tcgttgacca gaatacttcc aaaattcctg ctatgattaa ttccatccat
    15181 gccatactta cattcctcct taactataaa aaaatacaca aaaagaggaa aatcatccct
    15241 tcaaagacct aatggaatga tcatcctctt tatcctaccc ggtggcagat tgtatatctt
    15301 tttctgtagt atagcacacc tatccagata tcggcaatct catacttttt agtaaagtgt
    15361 accaagcact gacggatata tcgttagcgg aaaagaagat gaatgctttg caatttcata
    15421 gaaagaagtt gttatttatt aatcatttaa aaaaaacagt aactagacct tatttctata
    15481 tattatcggg caataaatta aaaaaagctt taccttacaa taagtaagat aatttttgtg
    15541 ataaaaaaat aacgaaaaat atttaaaaat agtgtctatt tcgtgagaaa acaactatat
    15601 tttttatgtg ttttgcttta taattaaaaa aatattgtca ttttatggag gaaaatatat
    15661 ggaaaattat cttagccttt taggcgtctt gattgttatt ctcgggtttg catttaaatt
    15721 agactcgata ttgatcgtaa tggttgcttt agttgttaca gctttgactg gcggtcttgg
    15781 cattcaagga atgttagaac ttttaggtac aagttttgta aacaatcgcg ggatggcgat
    15841 ttttatcatc attatgttgg caacaggaac gcttgaaaga aatggtctga aagaatcagc
    15901 ggcttccttg atcaagcgat tcaagaaagt atctgctggt atgattgtag atatttatgg
    15961 gatctttcga atgatctttg cggcttttaa cgtgagtttt ggtggagttg ctggatttgt
    16021 tcgtccaatc attttaccga tggcattggg gaccatcgaa tcaaaagggt tagaagtcca
    16081 tcctaagcat gaagaagaac taaaaggtat ggcttcagct atggaaaatg tctgctggtt
    16141 ctttggccaa gtactattca tcggaggagc aggggcgttg ctagtccaat caacactgaa
    16201 agatctagga tatgacgtaa cattgggaca gcttgcttta gtggaagttc cagtggctat
    16261 cacggcttta gttgtggcaa gtgtctactt ctatcttaaa gaaaagaaat tagcgaagaa
    16321 atattatcca ggaaaggggc aataagatgg acttttttac aaatcctgat attttattag
    16381 gcgataaatt actggagatc ctttatatcg tgatgggact cgtattgatt tacactggag
    16441 taagaaattt aacagataaa accaatcctc atcgttatgg gtcagccttt ttctggacgg
    16501 tcttaggggt agttattgca ggaggaagat ggcttccggc aatcgtgaac ggtggcttga
    16561 tctttgcgat gaccatacca gcaattgcta agaaagtcag caaaggagaa agccggcttc
    16621 catcaaaaga atatatggaa aaaatgtcag acaaactagg aatgaaaatt tttattccag
    16681 ctttgagtat cggtgtcttt gcgatcttgt ttgctctatt taccaattta ggtgctttag
    16741 tcggcgtggg cgtcggtgtt tttgcagcca tgctaatctt gatgttcttt tctcgagata
    16801 atcgaccaag tacattttta gatgatgcag cagatatgct gggcacagta gggccgttaa
    16861 gcatgttgcc aatgctttta gcttctctag gtgcggtatt tacaagcgct ggagttggga
    16921 cagtgatttc caatgcagta ggtacgatcg ttccagaagg aaatgtgaac atcggcatca
    16981 tcatttacgc tcttggcatg gtgatattta cggtaatcat ggggaatgca tttgcggcca
    17041 tcaccgtgat gacggttggg atcggtgcac cattcgtatt tagtcatgga gcgaatccag
    17101 cgttaatagg aatggttgca ttgacttgcg gtttttgtgg gaccctgctg acaccgatgg
    17161 ctgctaactt caatatcgtg cctgtagcga tgctggagat gaaagacaaa tacggagtga
    17221 tcaaaaacca gttgtttatt gcgttattta tgctagtttt ccaaattgct tatatgattc
    17281 tatttaaata atagaagaga ggggttgtga cagaataatt gtcgcaacct cttctaacat
    17341 tgtagtggaa cactattttt ttataagaat atattaagtt tgatctgtta tgttatttaa
    17401 actattgttt cctttattta cgctgttcaa ggaaaatggt atgataaaag ataaccatat
    17461 gttaaatcaa tcggacggag gaacaacaga tgaaagtact agtaacaggt tttgatccat
    17521 ttggtgggga caaagtgaat ccagcctatg aagcagtaaa aaaaatgcca gatgaaatca
    17581 gcggtgctga aatcatcaaa gtggaagtac cgaccgtatt cgaaaaaagc agtcaagtag
    17641 tcaaagaagc catccaacag caccaaccag atgtcgtgat ctgtgtcgga caagcaggtg
    17701 ggcggtcagc agtctcgttc gaacgtgtcg caatcaatct agcagaagca agaatccctg
    17761 ataatgaagg aaatcagcca ttcgatacgg ctttagaaga aaacggtcca gccgcttact
    17821 ttacctcatt gccaatcaaa gcaatgacaa aaaatgtaca agatcatggt ctaccagcgt
    17881 acatctctta tacagcagga acatttgtct gcaatgatat catgtatcgt ttgcttcatt
    17941 tgatcgaaac acaattcccg gcaattcgag gtgggttcat ccacgtgcca ttctcacccg
    18001 atcaagtgat cgatcgtcca gtgggtacgc cttctatgtc tttagaagac attgcttctt
    18061 ctttgactta tgcagttgaa gcagcagtag aaaataaaga agatatttcc ggaaatgccg
    18121 gaacaactca ctaatttagc aagaaacact ggctggttgc taacgttatg ttagtagcca
    18181 gctttttgta attagaaagg aaagaaacag ccgtggaaga atggcaatcc gtctttgaag
    18241 aatggtttcc aaaagaaatc agcaaaagct atcccatcaa aatttctaaa caatacacaa
    18301 gcagtcaacg ttgggagatc tatgcaaaat taacgaaaaa acagcgggaa ctagtcgata
    18361 agcaccgccg atatctaatc agctctcgtt ttatggaaga acattattta gctgcaacag
    18421 attgggtgtt ttctgacttc aagatcaatc cgttttttcg aacaaaacga agccagcaaa
    18481 aattgtattg tgagtgtggt agagaattaa aagtgcaata catcgttaaa tcgccaaaaa
    18541 ccggaaagat cctaaaacta ggcatcaacc actttgccga tcacctgcat gtctctccga
    18601 cagtggcagc ttcgatccat cagggaatga caaaagttga tctggcctta gacgaattat
    18661 tatggcttaa gcagaagaat atcgattttc ctgaaggact atggcaaaaa tactgttttg
    18721 tcttgtacca aaatcgtcgg atgaaacagc catatttacc ggatataaaa ttagctcagc
    18781 ggctcgcaga atttcgccaa gtagaaatgc cgatttacat agcggattat caagcattgg
    18841 aaaatgaaat caagaaaata agtgaacaca tcaatgggca gtcaaaaaag cgacagataa
    18901 aaaaagaact atttgacgac tttgcagaag aattagtaaa ggatgtagaa gaattcttga
    18961 tcaactatcg cgcattttta cgtaaagatt ggcaatccat cgtatatgaa gaagtgccag
    19021 tacatcctaa tgcttatttt gaaacattta tttccgtgtt gagaaagaca aaacgtcaac
    19081 gaacaccaga agtcactgct cagatggaat attttgcgaa aaaccaacga ttcatccaac
    19141 caaaaatcta tctatttatt tggaagcaat attgtcgcta tggttttaca gaagggttct
    19201 tcgacagcat tcctcggata gtcagaaatg gttttttaaa agtattgcgt aaagaacgag
    19261 aagctataca atctgctgat aagaaagacc gtacagtctc aaaagaaaaa tggcaactag
    19321 tagtgaaaga tatccaatct ggaaatgtgc aagagacaat cgacaaatgg aaaggaaaac
    19381 attatcgttt tactgaagct cagaaacaag cgttggaata ttatcagaag ttagaagaat
    19441 cactgcgttt caatgatgag gcaagaaagt atctgaagga attactataa aaaatagagg
    19501 ctgggacaga agcgtttaac tccaagaaat aagaa
//
LOCUS       DBBGSZ010000169        13213 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.guided.060, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000169 DBBGSZ010000000
VERSION     DBBGSZ010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.guided.060"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(204..2162)
                     /gene="nagE"
                     /locus_tag="ACIZE5_002945"
     CDS             complement(204..2162)
                     /gene="nagE"
                     /locus_tag="ACIZE5_002945"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HGC6110000.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(2159..3031)
                     /locus_tag="ACIZE5_002946"
     CDS             complement(2159..3031)
                     /locus_tag="ACIZE5_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGC6110001.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(3373..4245)
                     /locus_tag="ACIZE5_002947"
     CDS             complement(3373..4245)
                     /locus_tag="ACIZE5_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGC6110002.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            4373..4942
                     /locus_tag="ACIZE5_002948"
     CDS             4373..4942
                     /locus_tag="ACIZE5_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HGC6110003.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            5009..5746
                     /locus_tag="ACIZE5_002949"
     CDS             5009..5746
                     /locus_tag="ACIZE5_002949"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HGC6110004.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            5977..7245
                     /locus_tag="ACIZE5_002950"
     CDS             5977..7245
                     /locus_tag="ACIZE5_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HGC6110005.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            7732..8196
                     /locus_tag="ACIZE5_002951"
     CDS             7732..8196
                     /locus_tag="ACIZE5_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGC6110006.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            8180..8809
                     /locus_tag="ACIZE5_002952"
     CDS             8180..8809
                     /locus_tag="ACIZE5_002952"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGC6110007.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            9163..10641
                     /gene="msr(C)"
                     /locus_tag="ACIZE5_002953"
     CDS             9163..10641
                     /gene="msr(C)"
                     /locus_tag="ACIZE5_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HGC6110008.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            10688..11134
                     /locus_tag="ACIZE5_002954"
     CDS             10688..11134
                     /locus_tag="ACIZE5_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HGC6110009.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(11333..11848)
                     /locus_tag="ACIZE5_002955"
     CDS             complement(11333..11848)
                     /locus_tag="ACIZE5_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGC6110010.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            11965..13167
                     /locus_tag="ACIZE5_002956"
     CDS             11965..13167
                     /locus_tag="ACIZE5_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6110011.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         4116 a         2424 c         2708 g         3965 t
ORIGIN      
        1 agaggttgta aaaaagctgt tctgcatcaa gtaataagaa gagtcaaata aaaaatagct
       61 cttcatatgt tacgtttggc tggacttatt accgcggagt tggcaggaga acgccgtttt
      121 tattcggaaa aaggagctga gacaagattt ttgtctcagc tcctgtttgt ttatcgataa
      181 aaaagtctgg ggaagacgat ggctcaggct ttgttggaaa cagagccgat tttatcattt
      241 gcttttacat cacgtgcggg ttcgatttct aagctttgga ctttgtcgcc atttgtgaat
      301 acaacgacca tatccgtgtt tttgcctgca gattgaatag cggcaagatc aactaaagca
      361 atcaattgac ctcttgcgac tttttgacct tcttttacat ataaagtgaa tggttcgcct
      421 tttaagtcaa cagtgttgat gcccatatga agcaagactt cgataccagc atctgtttgg
      481 attccgacag catgtttcgt tgggaaaatg tttgtgatcg taccagcgat tggagagaag
      541 atttctccat tttctggtaa tacagcatag ccgtcaccca tcattttttc cgcgaataca
      601 tcatctgaaa cttcagtgat tggaatcagt ttcccatttg cgatagcgta aatatcttgt
      661 tcgatcgttc caccggcaaa tgtttctgtt ttaaccacgg tgtttgtttg tgcaggtcgt
      721 gttgcagcac caccatgtag ttttgccatc tcatctgcaa cgaattgtac ttctgtacct
      781 acgatgactt gcgcattttt tccgtcgatg atcttcatac caggtacgcc agtggctttg
      841 attttatttt gatcgatcag gcctgtatct ttgacttgca aacgaaggcg tgtagtacag
      901 ttatcgatcg aagttacatt gtcggctccg cctaatgcag cgtagatttt gcttgcttgt
      961 gccgcatatt tattgtctga attagtcgtt gcagtatcgt catctgaaag atctgcttcc
     1021 tcgcggccag gagtcatcag atggaatttt ttgatagcaa agttaaagcc aaagtagtaa
     1081 atcactgctg ttactaatcc ttggacgatc aacatcaatg gctgattcgc aatcggattt
     1141 ttcaaagata ggaagtaatc gacaaatccg gcactaaagg caaatcctgc tgtccaatgg
     1201 aagaatgcac tcactgctaa agaaatccca gtgaaaattg catgcaagac atataatggc
     1261 caagcaacga acataaatga gaattcaagt ggttctgtta caccagtaaa gaatgaagca
     1321 aaagctgctg ctaacatcaa ggaagctgtt tttgctttgt tttctggacg tgcatttctg
     1381 taaatagcat atgctcctgc tggaagcccg aacatcatga ttgggaaaaa tccagcttga
     1441 tacattcctg ttacgccttt tgttccttca gaagccaaaa atttaccaat atcattgatt
     1501 cctgctacgt caaaccagaa cacggagttc attgcttgat gcaatcctgt agggatcagt
     1561 aaacggttga agaagccata aagacctgca ccaccccagc ctaaactcaa aatgaattta
     1621 gcaaaagaaa ctaaagcaga gtaaaccgga ggccatacga gcagtagcac tgcactgatc
     1681 agcaacatga caaaggcagc caagattggc actagacgct tgccgctaaa gaaagataaa
     1741 gccatcggta attttgcttc gtggaaacga ttataaagag ctgccgcaat caatccggca
     1801 ataataccaa taaatacgtt actgatctga gcaaaagatg gatcaactga ttctggtttg
     1861 atattcaata aagtagctac tgaatcagtt tttaaaacat ttactggaac ttcaaatgcg
     1921 accaaacctg ccaaggcagc agcacctgat ttgtccactg acatccctag tgctaaccca
     1981 acggcaaaca gcaaaggtaa ttgacctaaa actgcgttac cgccagcttg taaaaaatga
     2041 gcgacaatgt cgttactata agatgcccac cagtttccga tccctactag taaagcagca
     2101 gcaggtaaga ccgcaactgg aagttgaagg gaacgtccca ttcgttgtag atatgctttc
     2161 aatttttttc ctcctcatga ttgttaacat ttgtttgtac gattgcgctt cttaaacgct
     2221 cgatatggat ggccaagtaa cccagttctt ctttcgtgat cgcgagctgg tattctttgg
     2281 tcagcaacac acggattttt ttagaaatct tatagctttc tgggtatttt cgtttgacca
     2341 tttctacgat ttccgtgtct aaaacagcat attgttgcgc atgggttcgt tgtagaagca
     2401 gtcgtaaatg attcaccagt cttgaataat tcagtgaaaa tggttctgaa tggatatctg
     2461 tttccaattc tgattccact aaatggatga tgtcagatac aatcgtcact tcacggatac
     2521 tgcgatggtt attgttccga ccgcttcgtc cgctgtgaat atggattgcg atatatcctg
     2581 cttcgtcata agtatatgga atcccaagct cttttgtcag atactctact gcccattgag
     2641 caatactgaa ttcatcactg taaagcactt cgatttctct taaaagtttg ttgcggatga
     2701 cgataccgtt attaatgttc tccgcagaaa aagcaatgtg gtcggtcaaa gcgatcaata
     2761 catgttcatt caacttttcc atcaaaacag tttccgcatg atcaatgatc gtttctgctg
     2821 caaataaaaa gcgttcatca atctgattaa gtaaattttg caacttgatt tgaccttctg
     2881 gttccatgac aaatatccgt tcgacatcac gatcaaaaat caaatcattt ctttttctgt
     2941 caaatccaat cccttttcca atagctactt tttcctgtcc accgtcatct accaatactg
     3001 cattttgatt aaagatcttt ttgattttca tgcgcgcacc ctttttgaag atttggtttt
     3061 cacgtttgct agaccagttg attgcggcca aacaaaaata gacacgaaaa acctcctagg
     3121 gaaaccatgt tcctcagaga tttttcatgc ctagtatgat ctagtcacat gaaacgaatt
     3181 attgttaacg taatcaattt tatatagaca gttatgtttt gtcaattctt tttttataat
     3241 tatagtaatt tactggaatt atcagaaata aaaggaagga acaaattaag aaacttatgt
     3301 tatttaatca ttggatcttt tgcttaactt attcgttgtt aaaaagctga aagcgaagga
     3361 aaaaaactct acttaactgt atttctccgt taggacatct aaaaatttac gagcagcagg
     3421 agaaagaggc tggtcttttt tccaaatgag attcagtgaa gcttgtaatg gcggatcgag
     3481 tgggatgaat actttttccg tcccataagt attgatgatc ccatctagag ctaatgcacc
     3541 aaaagtcccg ttatcgacca tcaaagaagc attgtacaat aagttatatg ttccgacgat
     3601 cgataactga tctatgctga aacctagcca ttcagctagt tgactgtcca ctgacgtttg
     3661 ccgggaaatg atcaaaggaa cagttttcag ttcctgcgga tggatgactg tttgctttgc
     3721 taaaggatga ttccgatgta tcaaaagtcc ccaacgatct tgggctggca gtcgaaatga
     3781 ctggtatttt tgtttgtttg tcggttcgat tacgagtcca aaatcaagta atccgctatc
     3841 cagtttgtct atgatatcat ctgcattccc gctatataaa tgaaactgga tatcaggatg
     3901 cgccttgatc aacgaatgaa ggctatcaga aatgaaagag attgctttag tttcgcctcc
     3961 gccaatgtag atttctccag agatgattgc gtcatttgtt aaattgttcg ccgttttttc
     4021 taccaacgac aagatttctt ttccttttga ataaagatat cgaccagaat ccgtcaactg
     4081 tatctctcgg gagcctcgag tgaaaagtgt cacaccaagt tcttcttcta aatctttcag
     4141 ttgttttgag agagtaggtt gcgtgatatg cagagatttt gctgctcggc tgatattttt
     4201 ttctctagct actgctaaaa aatacgtcag tatacgaata tccatttttt ccctcctgtt
     4261 tttaaaaaag cataccacta agtatagtta aaaggaatag ttaagtatgt tttataagta
     4321 ttagacatca taagccgtcc gttataaagt aaggataaaa ggagggagca aaatgacaag
     4381 cctcatcgaa aaacaaatcg tcaataaaga gattcgagta acggatccgc tctttgaagt
     4441 gatccatcag atccaagcgg aaaacgaaga gcctttagca gcgctgaata ctgggtacca
     4501 tgaaccagca gatatccgca aacggctaga aaatatcatt agtgacaaag tagatgatac
     4561 ggtgactgtt ctgctgcctt tttatacaga tttcggcaaa catattagta tagggaaaaa
     4621 tgtctttatc aatcgtcaag tgatgttcgt tgacttaggt ggcatctgtt tagaagattc
     4681 agtattgatt ggtcctcgtg tcaacctcat cacggtgaac catctaaccg atccaaaaga
     4741 acgaagaggc ttgtcagtaa agccaatcca catcaagaaa aatgcttgga tcggagcagg
     4801 agcaactatt ctgccaggcg taacgattgg cgagaatgcc attgttgcag cgaatgcaac
     4861 tgttacgaaa gatgtcccag acaataccat cgttgcagga atccctgcca aaatcgtcaa
     4921 acctgtcgaa cggattattt gaacagtaag atgaaataag agatagtgag tataagcaag
     4981 agatttttca aaacaggagg agaatagaat gaatgattta tcagaaaaag tgattgtcat
     5041 catgggcgct tcaagcggaa tcggtgaagc aacaacgaag ctattagcag aaaaaggggc
     5101 taaactagtt atagctgcac gccgagaaga tcgcctaaaa gcaataaaag aatctttacc
     5161 agaagctgag ctatatattc aaacagcaga tgtaagagat tttgcacaag tccaagcagt
     5221 tatcgattta gcgatggaaa agttcggtcg aatcgatgta ttgtacaata atgcaggaat
     5281 catgccaacc gctccattag ttgaaggtca ccgtgatgaa tggcaaaata tgcttgatat
     5341 caacatcatg ggtgtgttaa atggaatttc cgccgtactt ccaatcatgg aaaaacaaaa
     5401 atctgggcat atcatttcaa ctgattctgt ggcgggacat gttgtttatc ctgattccgc
     5461 cgtttattgc ggaacaaaat ttgctgtccg tgcaatcatg gaaggattac gtcaagagca
     5521 acggcaaaat aacatcaaat ctacgatcat ctctccagga gctgttcaaa ctgaattata
     5581 tcaaaccatc agcgacaaaa aggctgctct tgaacttcat gaagcgcaaa aagaatgggg
     5641 attaacatct gaagatatag cttctgctgt agcatttgcg atagaaacgc cagaccggat
     5701 gtctgtcagc aacatgatta tccgtccgac gacacaggaa gtataatcca taacggataa
     5761 tatccagaga gaattacttg ttaaatagtt attcaaacga ccatcaattt aaggcgtgaa
     5821 tggagaagaa tattcttcat ttacgtcttt ttatgcagaa aaagcaaatt tattaaaaag
     5881 aaacaaatgt tatttaaata tggacattga cttgctttta cttttttagt tacactgtta
     5941 tttaggaaaa gtttcataat tcaaaggaga aaaaagatga aagcaaagaa tttattattt
     6001 agcgttattc ttttaggaaa tctagcagtt gccaacacaa cagtgctagc tgaagaatcg
     6061 acagaaactg tcgcaactca gacatcgagt tcttcagaaa caggaattga aaacgataca
     6121 gaaagtactt tgcagtcagc tactgtctca gaaaatacaa tttcaaccga agaaccaaca
     6181 actgaaacaa cagaacaaac acaaaccgaa gacagtacat cagcagaagc tcagaacaat
     6241 ccagagaatg cagaagaaat cacgaaccaa ttgacagatg ggcaaacatt gacacatacc
     6301 catcaagcag atttgtctga attcgaaaac tatactggct atgcttttta tgctcgctca
     6361 tctgctaatt ctcaacaagc gttcattgat agtattgcct caactgcaca aagtttggca
     6421 agtgccaatg acttatatgc atcagtcatg attgctcaag ccatcgttga aagtggctgg
     6481 gggaacagta ctttggcttc tgcccctaat tacaatctat ttgggattaa aggaagctat
     6541 aatggccaat ctgttacgat gcctacttcg gaatatgtga atgggcaatg gattacggtg
     6601 aatgccgctt ttagaaaata tccttcgtac aaagaatcat tgcaagataa cgtaacggta
     6661 ttgaagacga cttcttttca gccaggcgtt tactactatt ccggtgcatg gaaaagcaat
     6721 acgaactctt acaaagatgc tacggcttgg ctaacaggtc gttatgccac tgcgcctaat
     6781 tatggttcta cattgaacaa tgtaatcgaa acctataatc tgacacagta tgatacagca
     6841 ccaacttcaa cttctccgat gtatcgtctg tataaccgtc atacaggaga acatttatat
     6901 acattgaatg ccggagaaaa aaattatctg ccaactgtag gctgggaata tgaagggatt
     6961 gcttggcaag caccaaacag cggacaacct gtctaccgtt tatacaatcc ttacagtgga
     7021 gaccatcatt acacaatggc acaatctgag atcaactctt taacaaaaat cggttggcgt
     7081 tatgaaggtc taagttttta ttctggtggt tccaagccaa tttatcgact atttaatcca
     7141 aatgaaaaaa ctggtaccca tcactatacc ttgagtgcta aggaaagaga ttggctaaca
     7201 ccgatgggct ggagatatga aggaatagga ttttatggtt attaaaaaga ggtagtgaaa
     7261 aagctgccct gcatcaagta gtaagaacag ccaaacaaaa acagattttc atgttttttg
     7321 tttggttgaa cttattaccg cagatgcaag tttttgaaca ccgtttactc aaaaaaggtt
     7381 gtgacaacat cttgtcataa cttttttatt actgtttaag catactgatc caatttctaa
     7441 tattcgacgg gattcttgca aaaggcgatt tcggaaattt ttggcggtgt aaaattatct
     7501 actgcagaag agctatcttc tatagtttga taagaatcaa taatcttggt tttagcgttg
     7561 tgctttcttt atcatttttt ccgttcattc tacaaaaaat ttcttttctc tatacttttc
     7621 tattgagagc gtttttttta ttacacagct gattctttga cttttttctt tttttattct
     7681 attattgaca agtcaatcgt tgacgagtca attattagaa aggaggaaat tatgtcttta
     7741 gaagagatta gtcacctttt atatcaaatc aaattagccg atcaaaaaat cgtccagatc
     7801 tttgaagaaa atatcggtat aagtcttact agatacgaga tcatgatgag actgaaagaa
     7861 gaaaatccat tgctacaaag cagtttgcaa gaaaagttgc agattgatca aggagcagtt
     7921 actcgtcatc tgaaggtatt ggaagcaaat ggctatgttt cgcgtcagag aaatcctcag
     7981 aacaaccggg aagtgtatgt agcgctaaca gaaaaagccc agaagaaaat caagcattgt
     8041 gaaatggacc ataaagatac aggttccgtg ctatccccgg ctttcagcga tgtagaaatg
     8101 aaacaatttc taacactttt agataaattg aatacccaac tttgcaatat aacaacagaa
     8161 acgaaagagg ttaataataa tggaacaaaa aaatgatttt tcaacaatta tgactggtag
     8221 aagatccgtt cgcgtatatg atgaaacata caaaatccca cacgaagaaa tgctggaaat
     8281 gatcaaagaa gcgacgactg caccttcttc tgtcaatatg aaaccatggc gctttgtggt
     8341 cgctgaaagc gaggaagcaa aagaaatctt gcgtcctttg atccgtttca atacgagaca
     8401 aaatgatact tcttctgcaa tggtcatgat ttttggcgat atgcaatgtt acgaatatgg
     8461 cgaagaaatc tacaaccaag cttacgaatc agggaagatg ccaaaagaag tcagagatca
     8521 acaattagct gcgatcattc cttattacaa gagtttttca agagaagaaa tgaacgatgt
     8581 agtcaaagtc gattctagct tagcggctat gcaattcatg ttagttgcgc gtgatcatgg
     8641 ctatgaaaca aatccaattg gtggattcga agcagatcag ttggcagagg catttggttt
     8701 ggataaagac cgttatgttc cagttattat tttatcaata ggaaaagcgg tagaagaagg
     8761 ttacgagtct gttcgtttag caccagaaaa gatcactatg ttcgaataaa aggttttcag
     8821 ttactattca gtagctattg ctttttttga atcgtgtgtg gtaacctaat aaaaaaggag
     8881 gtcggaaaaa tgactgcatc gatgaaatta cgtttcgaac ttttgaataa caactaaata
     8941 aattcaaaag acatgtataa acaacaattt catggatgga gtatgtccat tttttcgaac
     9001 gacagtagaa taggtgaaag ctatgacaga tttggtgatt tagtcatagt tatttcgttc
     9061 agagtaggaa aagatgtgat gcagtttttt tgcaaacaga tttttctgct cttttttagt
     9121 atcgataatt gttgttttac atgaaatagg agtgtaaaac atatggaaaa tttagcagta
     9181 aatataacaa atctacaagt cagctttggc aaccagctag aactatctat tgattctctt
     9241 cgtgtctatc agcaagatcg tatagggatc ataggagaaa atggtgtcgg taaatcgact
     9301 ttgctcaaac taatagccgg tgaacttttt cccgatcatg ggaaaatcca aacagagatc
     9361 accttcaact acctgcctca attaacctat ctcgctgaag caaaggacct aaatttggaa
     9421 ttagccagtc atttccagtt aagactggaa gaaacttcag agcggaaatg gagcggaggg
     9481 gaagaacgaa agatcgagtt gatacgtctt ctttcttctt atgaacaagg gatgcttcta
     9541 gacgagccaa caacccatct agatagaaaa agtattgatc gactgattga agagcttcgt
     9601 tattattatg gtacgctggt ttttgttagt catgatcgct attttctaga tgagctagca
     9661 tcgaaaatct gggaagtaaa agacggagaa atccgagagt tttcggggaa ttatagtgcc
     9721 tatctcactc aaaaggaatt ggagaaaaag actcagctac gagaagcaga gtcgatcatg
     9781 aaagagaaaa aacgattgga aaaatcgatc caagaaaaga aaaaacaagc ggaaaagttg
     9841 gaaaaagtgt ccagtaaaaa gaaaaagcaa caaatcagac tggatcggtt gtcttcctct
     9901 aaacaaaaag acagtgtaca aaaagccatc caaaagaatg cgaaaacatt agagagaaga
     9961 ctccaaaaaa taggagaaac aaccaagccg cagcagatga aacaaatccg ttttccagta
    10021 ccaaaatctc ttgaactcca cagccgctat cccatcatgg gacaaaatgt ccaattggaa
    10081 agaagtggga gaacattact ggtaaatggt gattttcagt tttctttagg taaaaaaatc
    10141 gcgattgtcg gtgaaaatgg ttcaggtaag acaaccttat tagaacatat ccgcaaacaa
    10201 ggagaaggaa tccttctctc tccgaaagta agctttcaag tatatcagca aaagggttat
    10261 caaatgacat ctgaagaatc catcattcgt tttgtcatga gacaaacaga gttttcagaa
    10321 tcgcttgtcc gtagtttgct gaatcactta gggtttgctc aggaaacttt gacgaaaccg
    10381 ttatgtacat taagtggggg agaagcgacc cgtctgacga ttgctttgct ttttactaag
    10441 ccaagtaatg tgttgctgtt agatgaaccg actaatttta ttgatatggc aacgatcgaa
    10501 gctttagaga agctaatgca aatatatccg ggaacgattt tgtttacttc tcatgattct
    10561 tactttgtcg agcgtacggc tgatgaagtt tatgaaataa aagggcagaa aataaaaaaa
    10621 gtacttacga gaaattttta aatgtgctac gatgattttc gtgacaaatt taaaggagtg
    10681 gtacagattg cctacaaata aaaaagaagg aataattttt acaacaatga tgtgtttttt
    10741 gatggtcttg gggatgagcg cgtataattt atggctgcat caagatcttc atttatcaag
    10801 tttgttgatt ggtctagtgc ctggattcgt ggtggctttc attttggatg tcttcatcat
    10861 cggtgtgctg gcgaaaaaaa ttgcctttaa actaccagta aatccagaaa gcaaggtcca
    10921 aatgatctta actatttcat gcttgatggt tttaggaatg gtgacatgta tgtctttatt
    10981 cggtgtgatc atggaacaag gaatacctga tcaattattc tctgcttata tgaatgcttg
    11041 gaaaatgaat gtgattgccg ctttaccgtt gcagttgatc atcgttggcc cgctttcaag
    11101 aagtgtgcta aaagcaattc aaagtaatga atgatggaac actgttattt gaaaaaaggc
    11161 cttggcatgc tttttgtcat agtctcttga atgcagttct agaaaaatag tgatccgaac
    11221 gataggtttt ggcctgtcgt tcggatcgct ttttcttttc caactgtatt gctcttttat
    11281 tgaagataat ttgctcttca atagatattt ctagaaaggt tctgtttatc ccttactcaa
    11341 aaaactgctg catttgttct cttacttgct gacaccattg gagttcctgc tgacaaagca
    11401 taattctgcg ctggatcaca acataacgtc caaattcttg tttcttgtct agcgagaggt
    11461 cattcaattt tttttgattt ttttgcatga ttttgttcag ctgttgttct ctagtgaata
    11521 gcagtccagt agctgttgtt ttatcgagcg tcgaaaaagc atagattttt gctagaaatt
    11581 catctttttg cgtaggagcg ggagtttcct ctttgatcca ttcctctaca agagcacgtc
    11641 cttcatcagt caagtggtag atcttttttt gagagtgctc gtctttgtcc aaaacggtca
    11701 cataaccctg ctggtctaac ttggcaagcg ttgtatagat ctgactgtga tgggcttccc
    11761 aaaaaattgt gatcagctgc ttcaattcat acccagaacg tggtttggat aaaagcacgc
    11821 ataataatat ataggctaaa gtattcataa aaatcctacc tctcgtctta ttttctttat
    11881 tatatcacag taaagtttcc acgttttaca tgtgcatatt gacatgtaaa ataaatcatg
    11941 tatgatgcta atagagagaa agggatggaa atattggaga atcaaataga tatacaagaa
    12001 caaacaaatg aagaaacaaa ggggaaaagt tcagcgctag ttgtagcagc tacctgtatg
    12061 atcgctttta tgggagtggg tctagtagac ccaatcttaa aaacgattgc tgcacagtta
    12121 aacgctacgc cagctgaaac gaccctgtta tttactagtt acatgttagt cactggtgtg
    12181 gtgatgctat ttacaggttt cttatctagt cggatcggtt tgaaaaaaac attgatgaca
    12241 ggattgttta tcatcgttgt attcgctggt cttggcggat tatctgggaa tatcggaatg
    12301 ctgattgggt tacgtgccgg ctggggtgtc gggaatgctt tatttgtctc tactgcttta
    12361 gcaacgatcg tcagtatttt agttggtaac acagaaaaag caatcatgat gtatgaagca
    12421 gcacttggct gcggaatggc tgttggccct ctagtcggtg gggtcttggg cagtggttca
    12481 tggcgttatc cattttttgg ggtagcattt ttgatgtttt gcggttttat agccctagcg
    12541 gtacttttac ctgaaactga gaaaccaaag agaaaagtag gcctttggga aggtgtcaaa
    12601 gcgttaagca atcataaact tcgttcagtt ggactaatcg cattgttata taatttcgga
    12661 ttctttactt tacttgcgta tgcgccattt ttattgattg gctattctga attagaagtc
    12721 ggttttgtat tttttggctg gggtgtgctt ctggctattg cttcgatttt cgttgcaccg
    12781 gctcttgagc ggaagtttac gacttatcgg acaattttag cagcatttgt cttattcatt
    12841 atttgtttgc tgttattagg agctggaact tctatgccag tccttgtacc gatcagcatt
    12901 gtgttagcag gatttttcca aggaattatc aatacactgt tgacgacgat tgctatggaa
    12961 ataccaggtc tgcaacgaaa cgttgcttcg tccagctata gttttgtccg ctttttcggt
    13021 ggagctttag caccatttat tgcaggtgtg attggtgaac atattggtga aagctatgcg
    13081 ttttattttg caggtgccat tgttcttatc agtgtatgtt gtatcattta tcaccgtaat
    13141 tattttgcta caaatgaaga agaataagaa atcagaggtt gtgaaaaagc tgtcctgcat
    13201 caagtcataa gaa
//
LOCUS       DBBGSZ010000170        10087 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.guided.069, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000170 DBBGSZ010000000
VERSION     DBBGSZ010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10087
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.guided.069"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            353..523
                     /locus_tag="ACIZE5_002957"
     CDS             353..523
                     /locus_tag="ACIZE5_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6110012.1"
                     /translation="MKKFIYRVLENDEVVAIFNEQQYAQDFIAYEKTISDKQFEIEKV
                     DIADWLLQPREF"
     gene            537..1139
                     /locus_tag="ACIZE5_002958"
     CDS             537..1139
                     /locus_tag="ACIZE5_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6110013.1"
                     /translation="MAKIGYARVSSKEQNLDRQLKALEGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVVVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINNLVIELYKYQAESERKRIKERQAQGIEIAKKKGKFKGRQPKFKENDPRLQHAF
                     DLFLNGCSDKEVEEQTGINRRTFRRYRSRYNVTVDQRKKQ"
     gene            1155..1832
                     /locus_tag="ACIZE5_002959"
                     /pseudo
     CDS             1155..1832
                     /locus_tag="ACIZE5_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            2143..2640
                     /locus_tag="ACIZE5_002960"
     CDS             2143..2640
                     /locus_tag="ACIZE5_002960"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HGC6110014.1"
                     /translation="MLFLRDGEIKATLTTMMNKLAFSHKLILEPLFKSVSQIDEESDR
                     ERMDAIDKLMEQLLEERNTLIALMSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTN
                     SASGVLRANEIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLK
                     EKVVR"
     gene            2641..3057
                     /locus_tag="ACIZE5_002961"
     CDS             2641..3057
                     /locus_tag="ACIZE5_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HGC6110015.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            3077..4621
                     /locus_tag="ACIZE5_002962"
     CDS             3077..4621
                     /locus_tag="ACIZE5_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6110016.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            4764..4988
                     /locus_tag="ACIZE5_002963"
     CDS             4764..4988
                     /locus_tag="ACIZE5_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6110017.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            5003..5872
                     /locus_tag="ACIZE5_002964"
     CDS             5003..5872
                     /locus_tag="ACIZE5_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HGC6110018.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            5853..6587
                     /locus_tag="ACIZE5_002965"
     CDS             5853..6587
                     /locus_tag="ACIZE5_002965"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC6110019.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            6620..7528
                     /locus_tag="ACIZE5_002966"
     CDS             6620..7528
                     /locus_tag="ACIZE5_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HGC6110020.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            7525..8067
                     /gene="sat4"
                     /locus_tag="ACIZE5_002967"
     CDS             7525..8067
                     /gene="sat4"
                     /locus_tag="ACIZE5_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HGC6110021.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            8160..8954
                     /locus_tag="ACIZE5_002968"
                     /note="aph(3')-IIIa"
     CDS             8160..8954
                     /locus_tag="ACIZE5_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HGC6110022.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            9230..9361
                     /locus_tag="ACIZE5_002969"
                     /pseudo
     CDS             9230..9361
                     /locus_tag="ACIZE5_002969"
                     /inference="COORDINATES: protein motif:HMM:NF024804.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
     gene            9437..9930
                     /locus_tag="ACIZE5_002970"
                     /pseudo
     CDS             9437..9930
                     /locus_tag="ACIZE5_002970"
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
BASE COUNT         3548 a         1572 c         2207 g         2760 t
ORIGIN      
        1 acaagaagca ttttattcta gcttaatttg acaaatcata ctatgatacg tgtttgtttt
       61 tctgtgctgt ttagtgaatg attagcagaa atatagagag taagatttta attaattatt
      121 agggggagaa ggagagagta gcccgaaaac ttttagttgg cttggactga acgaagtgag
      181 ggaaaggcta ctaaaacgtc gaggggcagt gagagcgaag cgaacacttg atcttttaag
      241 ttgctatctt tttaaggtca atagagtata cttatttgtc ctaatatggt tttagcagta
      301 taattgactt ggtgaatagg tcatttaagt tgggcataat aggaggagta aaatgaaaaa
      361 atttatttat cgagttttag aaaatgacga agtggtggct atttttaatg agcaacaata
      421 tgcgcaagat tttatcgctt acgaaaagac aatttctgat aagcaatttg aaattgaaaa
      481 agtagatata gctgattggt tattgcaacc gagagaattt tagaggttgg ttgaaaatgg
      541 ctaaaattgg ttatgcacgt gtcagtagca aagaacagaa cttagataga caactgaaag
      601 cgttagaggg cgtttctaag gtcttttcag acaaattaag cggtcaatcg gtcgaacgcc
      661 cacaattaca agctatgctt aactatattc gtgaagggga tatagttgtt gttactgaat
      721 tagatcgatt aggacgaaat aataaagaat taacagaatt gatgaatcaa attcaaatta
      781 agggggcaac cctggaagtc ttaaatttac cctcaatgaa tggtattgaa gatgaaaatt
      841 taagacggct gattaataat ttagtgattg aattgtataa gtaccaagcg gaatctgaac
      901 gcaaacgaat taaagaacgc caagcccaag gaattgaaat tgctaagaaa aaaggaaaat
      961 tcaaagggcg acaacctaaa ttcaaagaaa atgatccacg tttacaacac gctttcgatt
     1021 tatttttgaa tggttgttcc gataaagaag ttgaagaaca aactggaatt aatcgccgaa
     1081 cgtttagaag gtatcgatca agatacaacg tgacagtaga tcaaagaaaa aaacaatgaa
     1141 aagagggata gttaatgagt acggttattt tagctgaaaa accaagccag gcattagcct
     1201 acgcaagtgc tttaaaacaa agcaccaaaa aagacggtta ttttgagatc aaagacccac
     1261 tatttacaga tgaaacgttt atcacctttg gttttgggca tttagtcgaa ttagcagaac
     1321 caggtcatta taacgaaaag tggcagaact ggaaacttga atctttgccg atttttcctg
     1381 atcgatacga ttttgaagtt gcaaaagata agggaaagca gtttaaaatt gttgctgaac
     1441 ttctcaaaaa ggcaaataca attattgtcg caacagatag cgacagagaa ggtgaaaata
     1501 tcgcctggtc gattatccat aaagcaaatg ccttttctaa agataaaacg tataaaagat
     1561 tatggatcaa tagcttagaa aaagatgtga tccgaagcgg ttttcaaaat ttgcaaccag
     1621 gaatgaatta ctatcccttt tatcaagaag cgcaaacacg ccaaattgcc gattggttga
     1681 tcggcatgaa cgcaagccct ttatatacct tgaatttaca acaaaaaggc gtacaaggta
     1741 cattttcatt aggacgtgta caaacaccga ctttatatct catttatcaa cgccaggaag
     1801 caatagaaaa ctttaaaaaa gaaccttttt tcctgaataa ttcatagttt tactaatagt
     1861 ctttcctaac attgatttaa tagtctttaa agtattctgc ttcatcaccc attaggtgat
     1921 gaaaaaagaa cccctttctg atttagcgga caaatacttt gacctaatct cagaagatat
     1981 aaaagaaaaa ataataaaat atccgattta tactttgtat aaagaactaa agtagttagc
     2041 aaatcattta cagcaaatca ctatgttcca cataccattt tacatactta ccttatccac
     2101 gacacatgtt gagatagtat cgaagataaa gaaagttgct ccatgttgtt tttgcgagat
     2161 ggggaaatca aagccacatt gacaaccatg atgaataagc ttgctttcag tcataagcta
     2221 atcctagaac cacttttcaa gtcagttagc caaatcgatg aagaaagcga ccgtgaaaga
     2281 atggacgcta ttgataagct aatggagcaa ctattggaag aacgcaatac ccttattgca
     2341 ctgatgtcca aaggtttcct agaacctgct ctttttaatc aggaacgaaa tgttttagat
     2401 agtgagatta aaaatcttac taccgaaaaa acaaacctgg taacgaactc tgcgagtggg
     2461 gttttgcgag caaacgagat aaaggacctc attaattatg tgtcagcaga taattttaat
     2521 ggtgactaca cggaagaact atttgaagaa tttgtagtga acatcattgt aaattccagg
     2581 gatgagctga cattcaattt gaaatgcggt ctttccctga aagaaaaggt ggtgagataa
     2641 atggcatata ttccatatgg atacaaaatt caagatggag tggttactgt cgatgaaaag
     2701 gcagcaggtc aagtaaaggt attctttgag aaatacatat caggactatc ccttacagtg
     2761 gctggcgaac aggcaggtat tgaaaagaca cattctgtga tggggcgcat tttgaaaaac
     2821 gtcaactacc ttggaaatga tacgtatcca gcaattattg ataaagagat atttgataaa
     2881 gctgaagaag ttagagataa acgtgcaaag gatttaggac gagtggtaga gcttgccgct
     2941 ttcacctctc cccctcccaa agaacgattc aaaatgaaaa aggcagataa taagatgcca
     3001 gtggatcctt ttgaacgagc agaatactta tacagtctga tagaaagcga ggaataaagt
     3061 gacagagaaa aatataatgg ttattcctgc tcgtaaaaga gtaggaagta cagccgcaaa
     3121 agaaaagata aagaaacttc gtgttgctgc ctattgccgt gtttctacag aaacagaaga
     3181 acaaaattct agctatgagg ttcaggtctc acactataca gagtttataa agaaaaataa
     3241 tgaatgggag tttgctggca tctttgcaga tgatggtatc tctggtacga acactaaaaa
     3301 gcgtgacgaa tttaatcgca tgattgcaga gtgtatggac ggtaacatcg acatggttat
     3361 tacaaaatcc atcagccgat ttgcgcgtaa caccctagac tgccttcaat acattagaca
     3421 gctcaaggat aagaacatat cagtttattt tgagaaagag aacatcaaca ccacggatgc
     3481 caaaggtgag gttttgctga ctattatggc atctttggca cagcaggaaa gccagagcct
     3541 ttcacaaaac gttaagcttg ggctacagta ccgataccaa caaggaaagg tgcaggtcaa
     3601 ccataagcga tttatgggct acacgaaaga tgaagatgga aatttaacta ttgtccccga
     3661 agaagctgag attatcaaac gcatctaccg agaatacctt gagggtcaga gtctagtggg
     3721 cattggtcga gcccttgaaa aggatggtat tttaacagca gcgggaaaac caagatggcg
     3781 accagaatca gttaagaaga tacttcaaaa cgaaaaatac atcggagatg cccttctgca
     3841 aaagactgtc acagtagatt ttctgaccaa gaaacgagtg aaaaatgaag ggcatgttcc
     3901 ccaatattat gttgaaaata gccatgaagc gattattcct aaagagttat ttttgcaggc
     3961 gcaagaagaa attcatcgga gaagcaatat ctacacagga gaaggcaaga acaaaagaat
     4021 ttacagtagc aagtacgctt taagtgccat caccttctgt ggagattgtg gcgatattta
     4081 tagacgggtc tattggaata tccacggaag aaaagaattt gtctggcgat gcgtgactag
     4141 aatcgagcaa ggtcctgaag tttgtaagaa ccgaaccgta aaagaagatg aactttatgg
     4201 tgcagtaatg actgcgatta ataagctact tgcaggtggg aacaatatga taaagacact
     4261 ggaagagaat attcatgctg tgattggcga aaccacagaa taccaaattt cagagattaa
     4321 caactcacta gaggaaaaac aaaaagaact aatcaagctg gcgaacaagg gtcaagacta
     4381 tgaccactta gcagatgaga ttgatgagct gagagacaag cgacagatcc ttttagtaga
     4441 agatgcctcc ctcagtggcg agaacgagcg aatcaatgag ctgattgaat ttatccgcaa
     4501 gaacaaattc cgcaccttag aatatgatga taagcttgta aggaagataa tccagagcgt
     4561 tacagtctat gaaggccact tcgtcatagc cttcaaatct ggcatcgaaa tggaaatatg
     4621 aaaaccagaa gtaaatagcc catgactcta cagtagagtt gtgggttttc ttttgcttgc
     4681 tgattataat aatattttaa taactattgt gtttatcaac caaatggttt ataatattct
     4741 tagcgtaaac ttggaggtgc tgtatgacta cggcagaaat gattaaagaa ctgtgtgagc
     4801 aaatgaatat aagtgtttcc gaacttgcta gacgtattgg ccagactcca cagaatttca
     4861 ataaaaaatt acaacgagaa acagtaacct tggatgagtt gaaggccatt gctgatgtgc
     4921 taggtgtcaa gtttgtgcag gcatttattt taccagatgg agaagaaata aaaatatcta
     4981 acgaataaag gaggatgttt atatggtagg taatgttatt caaatagtaa cagagaaatt
     5041 atcatctttg ccttttatag aaggcatcgt attagggggc tcacgtgcaa gaggcaccca
     5101 tacagaaaat tctgatatag atatcggaat ctattacaat tcagactcat ttgacctgac
     5161 agcgattaat caaattgcta cagagttgga tgatgagaat agaaacaacc ttgttgtacc
     5221 tcccggagcg tggggtgatt gggttaatgg cggtggatgg ttagttataa acgggtgtca
     5281 tgttgacttg atattacgtg atataaaacg ggtggaacaa ataatcaaag atacggagca
     5341 aggaattgtt actgccaatt atcagaccgg gcatccccat ggttatataa gtgctatgta
     5401 tcgtggagaa ttagcgatta gtaaaatact atatgctaag aacgaaagct tatgcgaatt
     5461 aaaaaagcag gcagaaattt accctactgc tctaaagaaa agcttgatga acttttttat
     5521 atttgaagct gaattctctt taatgtttgt aaaagcaaat gcgggggcag aggataaata
     5581 ttatattgca ggccatgttt ttcgtattat ttcatgctta aatcaagtac tatttgcatg
     5641 taataatgct tattgcatta acgaaaagaa agctataaaa ctgcttgaaa cttttgaata
     5701 taaacctgaa aaatatgccg aaagagttaa tcatattttt gaagtactcg gtctttctct
     5761 ttttgaatgc tacgacatga ccgagaaact ttataaagaa gtgaatgaaa ttgtatcgga
     5821 gataaataac tttttaaacg aggagagttc agatgaaaga aaacaaatat gatgataata
     5881 tattttttca aaaatacagt caaatgagtc gctcgcagaa aggactggct ggtgcgggag
     5941 aatgggagac tttgaaaaag atgctacctg attttaaggg taagcgtgtg cttgatttag
     6001 gatgcggcta tggatggcac tgtatatatg cgatggaaaa cggtgcttcc tctgtagtag
     6061 gtgttgatat ttctcataaa atgctcgaag tagcaaaagg aaaaacccat tttccacaga
     6121 ttgaatatga atgctgtgcc atagaagatg tggatttccc agaggagagc tttgatgtaa
     6181 tactaagttc gcttgcgttt cattatgtag cagactatga gaatttaata aaaaagatat
     6241 ataggatgct gaaggctggt ggcaatttag tttttacagt tgaacatcct gtttttactg
     6301 ctcatggaac acaagactgg tattataacg aaaaaggaga aatactgcat ttcccggtgg
     6361 acaattatta ttatgagggc aaacggacag ctatgttttt ggaagaaaag gttacaaaat
     6421 atcatagaac actgaccaca tatctaaata cactgctttc aaatagtttt ataataaatc
     6481 agattgtgga gccacagccg ccagagaaca tgatggatat tccggggatg gcggatgaaa
     6541 tgcgacgccc aatgatgctg attgtatcgg caaaaaagaa gatgtaataa tatagaaaaa
     6601 ataaacgagg agtatgtaaa tgagatcaga aaaagaaatg atggatttag tactttcttt
     6661 agcagaacag gatgaacgta ttcgaattgt gacccttgag gggtcacgcg caaatattaa
     6721 tatacctaaa gatgaatttc aggattatga tattacatat tttgtaagtg atatagaacc
     6781 gtttatatct aatgatgact ggcttaatca atttgggaat ataataatga tgcaaaagcc
     6841 ggaggatatg gaattattcc cacctgaaga aaagggattt tcctatctta tgctatttga
     6901 tgattacaat aaaattgatc ttaccttatt gcccttggaa gagttagata attacctaaa
     6961 gggcgataaa ttaataaagg ttctaattga taaagattgt agaattaaaa gggacatagt
     7021 tccgactgat atagattatc atgtaagaaa gccaagcgca agggagtatg atgattgctg
     7081 caatgaattt tggaatgtaa caccttatgt tattaaagga ttgtgccgta aggaaatttt
     7141 atttgctatt gatcatttta atcagattgt tcgccatgag ctgctgagaa tgatatcatg
     7201 gaaggtcggc atcgaaacag gctttaaatt aagtgtaggc aagaactata agtttattga
     7261 aaggtatata tccgaggatt tgtgggagaa acttttgtcc acctaccgga tggattccta
     7321 tgaaaacata tgggaagcat tatttctatg ccatcaattg ttcagggcgg tatccggtga
     7381 ggtggcggaa aggcttcatt atgcctatcc ggagtatgat aggaatataa caaaatatac
     7441 cagggacatg tataaaaaat acactggtaa aaccggctgc ctggatagca catatgccgc
     7501 tgatatagaa gagaggcggg aacagtgatt acagaaatga aagcagggca cctgaaagat
     7561 atcgataaac ccagcgaacc atttgaggtg ataggtaaga ttataccgag gtatgaaaac
     7621 gagaattgga cctttacaga attactctat gaagcgccat atttaaaaag ctaccaagac
     7681 gaagaggatg aagaggatga ggaggcagat tgccttgaat atattgacaa tactgataag
     7741 ataatatatc tttactacca agacgataaa tgcgtcggaa aagttaaact gcgaaaaaat
     7801 tggaaccggt acgcttatat agaagatatc gccgtatgta aggatttcag ggggcaaggc
     7861 ataggcagcg cgcttatcaa tatatctata gaatgggcaa agcataaaaa cttgcatgga
     7921 ctaatgcttg aaacccagga caataacctt atagcttgta aattctatca taattgtggt
     7981 ttcaaaatcg gctccgtcga tactatgtta tacgccaact ttgaaaacaa ctttgaaaaa
     8041 gctgttttct ggtatttaag gttttagaat gcaaggaaca gtgaattgga gttcgtcttg
     8101 ttataattag cttcttgggg tatctttaaa tactgtagaa aagaggaagg aaataataaa
     8161 tggctaaaat gagaatatca ccggaattga aaaaactgat cgaaaaatac cgctgcgtaa
     8221 aagatacgga aggaatgtct cctgctaagg tatataagct ggtgggagaa aatgaaaacc
     8281 tatatttaaa aatgacggac agccggtata aagggaccac ctatgatgtg gaacgggaaa
     8341 aggacatgat gctatggctg gaaggaaagc tgcctgttcc aaaggtcctg cactttgaac
     8401 ggcatgatgg ctggagcaat ctgctcatga gtgaggccga tggcgtcctt tgctcggaag
     8461 agtatgaaga tgaacaaagc cctgaaaaga ttatcgagct gtatgcggag tgcatcaggc
     8521 tctttcactc catcgacata tcggattgtc cctatacgaa tagcttagac agccgcttag
     8581 ccgaattgga ttacttactg aataacgatc tggccgatgt ggattgcgaa aactgggaag
     8641 aagacactcc atttaaagat ccgcgcgagc tgtatgattt tttaaagacg gaaaagcccg
     8701 aagaggaact tgtcttttcc cacggcgacc tgggagacag caacatcttt gtgaaagatg
     8761 gcaaagtaag tggctttatt gatcttggga gaagcggcag ggcggacaag tggtatgaca
     8821 ttgccttctg cgtccggtcg atcagggagg atatcgggga agaacagtat gtcgagctat
     8881 tttttgactt actggggatc aagcctgatt gggagaaaat aaaatattat attttactgg
     8941 atgaattgtt ttagtaccta gatttagatg tctaaaaagc tttaactaca agctttttag
     9001 acatctaatc ttttctgaag tacatccgca actgtccata ctctgatgtt ttatatcttt
     9061 tctaaaagtt cgctagatag agttctatat tagagatgta aagagttttg gtgaagaggt
     9121 ttgtgagtat ggcttttata accagggtgc aatgagaagc actaacagca gctagcttaa
     9181 gaacgcatag gatatacttt ttatggaagt cacagaggag gaataaaatt tgaacaggat
     9241 taacagagta acctctattc ttattcagct gcaatcaaaa aaaataattc ctgccaaaga
     9301 aattgcacag cgatttaata taagcttaag gacagtttac agagatatcc ggacacttga
     9361 agaagccgga ataccaattg gatctgaggc cggaaaagga tattttcttg tagagggctt
     9421 cctacttccg ccggtaatgt ttacagcggc ggaagtgggt gcattgatta cagcagggaa
     9481 atttttaaat tgccatggag atgaatcatt tataaaggat tttgattcag ctatgtataa
     9541 aatcaaatct attttgaagc atggtgaaaa aaactatgca caggagttgg agaacagtat
     9601 taacgtgtac agcacatctg gacagaaaaa tacattggcg gataacgtta ttgcagcaat
     9661 tcagactgca atctgcaata aaagggtaat atcaattcaa tatcctgcat caggagggca
     9721 agaaccggaa agcagaatga tagagcctat atcactgggg ttttatgaac agaactggta
     9781 cttaatcggt tttgcaggct aagaaatgaa tataggaatt ttcgtgtgga tcggattaaa
     9841 agcatttgca tagaagaaga gctctgtcaa agccatgatg gctctttgga acaaatatta
     9901 aaacaaatgc tttcatataa aaaactatat gccctacaat gccgttgtaa aaattgggga
     9961 aaagggatat attgatttta tatctttctc aaaataaata taaaagccct ttaaagaggg
    10021 cttttatata ttaatcacaa atcacttatc acaaatcaca agtgattaat cacaaatcac
    10081 ttgtgat
//
LOCUS       DBBGSZ010000171         7958 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.guided.073, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000171 DBBGSZ010000000
VERSION     DBBGSZ010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7958
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.guided.073"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            128..1564
                     /locus_tag="ACIZE5_002971"
                     /pseudo
     CDS             128..1564
                     /locus_tag="ACIZE5_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            1753..4200
                     /locus_tag="ACIZE5_002972"
     CDS             1753..4200
                     /locus_tag="ACIZE5_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HGC6110023.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="ACIZE5_002973"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="ACIZE5_002973"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HGC6110024.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            5487..5693
                     /locus_tag="ACIZE5_002974"
     CDS             5487..5693
                     /locus_tag="ACIZE5_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6110025.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(5690..6793)
                     /locus_tag="ACIZE5_002975"
     CDS             complement(5690..6793)
                     /locus_tag="ACIZE5_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HGC6110026.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7345..7893
                     /gene="aac(6')"
                     /locus_tag="ACIZE5_002976"
     CDS             7345..7893
                     /gene="aac(6')"
                     /locus_tag="ACIZE5_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HGC6110027.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2665 a         1358 c         1729 g         2206 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacataa ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatta agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taatttttta ttttataagt aagataaata atgaaagaat agagatactg
     7261 attggtagct aaagattttt gagcgagaac atttcgtttt ttcaaaagga ctgttagaat
     7321 aagcaagaac aagggggaag acgtatgata atcagtgaat ttgaccgtaa taatccagta
     7381 ttgaaagatc agctttctga tttactgaga ctgacttggc cggaagaata tggagacagc
     7441 tcggcagaag aagtagaaga aatgatgaat ccagaacgaa tcgcggtagc agcggtagac
     7501 caagatgagt tagtaggatt tattggtgca atccctcaat acggtatcac aggttgggaa
     7561 ttgcatccat tagttgtaga aagctcccga cgaaagaacc aaataggtac tcgattagtc
     7621 aattacttag aaaaagaagt agcttccaga ggaggaatca cgatttattt aggtacggat
     7681 gatttagacc atggaacaac gttaagtcaa acggacctgt atgagcatac atttgataaa
     7741 gtggcttcca tccagaacct tcgtgaacat ccgtatgaat tctatgaaaa attaggttat
     7801 aaaatcgtag gtgtcttacc aaatgcaaat ggctgggaca aaccggatat ttggatggca
     7861 aaaacgatta ttcctcgacc aaattctcaa taataaaaag aggttgtgac agaagtaatc
     7921 agcttcaaga aataagaagg aatttacgaa aattactt
//
LOCUS       DBBGSZ010000172         6500 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.guided.082, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000172 DBBGSZ010000000
VERSION     DBBGSZ010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6500
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.guided.082"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(125..361)
                     /locus_tag="ACIZE5_002977"
     CDS             complement(125..361)
                     /locus_tag="ACIZE5_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6110028.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(544..915)
                     /locus_tag="ACIZE5_002978"
     CDS             complement(544..915)
                     /locus_tag="ACIZE5_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HGC6110029.1"
                     /translation="MSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECICVQSI
                     SYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAACSKRM
                     RRRKEAERQRKRYWKPTHLEL"
     gene            complement(912..2240)
                     /locus_tag="ACIZE5_002979"
     CDS             complement(912..2240)
                     /locus_tag="ACIZE5_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HGC6110030.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(2201..2530)
                     /gene="mobC"
                     /locus_tag="ACIZE5_002980"
     CDS             complement(2201..2530)
                     /gene="mobC"
                     /locus_tag="ACIZE5_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HGC6110031.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(2788..3158)
                     /locus_tag="ACIZE5_002981"
                     /pseudo
     CDS             complement(2788..3158)
                     /locus_tag="ACIZE5_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            3303..3488
                     /locus_tag="ACIZE5_002982"
     CDS             3303..3488
                     /locus_tag="ACIZE5_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGC6110032.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            3646..3813
                     /locus_tag="ACIZE5_002983"
     CDS             3646..3813
                     /locus_tag="ACIZE5_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6110033.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            4431..5090
                     /gene="vanR-B"
                     /locus_tag="ACIZE5_002984"
     CDS             4431..5090
                     /gene="vanR-B"
                     /locus_tag="ACIZE5_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-B"
                     /protein_id="HGC6110034.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            5093..6436
                     /gene="vanS-B"
                     /locus_tag="ACIZE5_002985"
     CDS             5093..6436
                     /gene="vanS-B"
                     /locus_tag="ACIZE5_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-B"
                     /protein_id="HGC6110035.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPNFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
BASE COUNT         1618 a         1534 c         1618 g         1730 t
ORIGIN      
        1 tgcgtaggtt gcagctataa ttagacccct gaaacagata tagccgcgca gcgggtgtat
       61 ctgtttcagg ggtgtgcagg tgatagccgc aaagcggcgt aagagggtgc agccctcttg
      121 ccgtctatct ctgttccagc gggaagctcg gcaatgcttc cagcagtttc agggaaatgc
      181 gctgccgtat atcttcgtca atgactttct tctttttgcc gtttgcctgt ctgatctcca
      241 ccgtggaaag ctcgttgatg tagtcagcat aatgggccaa cactttttcc gtggcccacc
      301 tctcaccggc aacggcggct ttgatcgttt catagtccag cagcttttct tgtccgtcca
      361 tcctgatacc cccgtcagac tgattttttc tatgatacca tattcggaag catggaacca
      421 gagaaaacgg cgcttttctg ctggtaaatt ctacgcattt agaacagcac ttcggcgggg
      481 ataggataaa acacccacat accccgctga ccatgccgga aaagccttga aatataaggg
      541 cttttacagc tctaagtgcg taggtttcca gtatcttttc cgctggcgct cggcctcttt
      601 gcggcggcgc atccgtttgg agcaggccgc gcagtatttg gcccggttag acttcggcgt
      661 gaacgtggcc ccgcactcac agcagcgttt cacttcgtcc cggtctttgg tgatctcggc
      721 atacagggcc gcatccagcg ggaggacagc ggccttaaac cagcggcaca gaagcgaata
      781 ggaaatgctc tgtacgcaaa tacattcttc gccgtcgtcc agcaacaggc agttgccgtc
      841 acaatagttg cagcactcat gcgtcagctt ccgggccttg cgatattgag ggtaattcat
      901 tcgtggaata ctcatagctc ttgcgtccat tcctttcccg gcgtcatacg caaaatgccg
      961 tccacattct gcttgatgat gccgtattcc tgcatctgct ttttcgcttc gccgtacttc
     1021 tcatacagcc gttccttttc ctcggccaat cgcttgtact cggctttcag ggcgtacaga
     1081 tcggggagct ttttcacacc ctgtcccttt agggcctttg ccgcagcttc atacaaaatc
     1141 aacgtgcttt catgctcacg ccggaatttt gccttatccg ctgcattgcg gtattccata
     1201 gccacgggcc agagctgctt gtaggtagaa atattcttta tcagcaccgc catatccgca
     1261 agccggtgtt ccatagcttt gagggtagcg gcggcctcgt cgctggcggc ggtgatctcg
     1321 gccactttgc tttccaaatc cgggtaggtg tctatcccat gttcagtcag gaaattcaaa
     1381 gtctttgcgg cctgcttcaa attgtggagc ttcgcccacc tctcatagcc tgccgactgc
     1441 tgggccttaa tgttgttttc cagatcaatc cgcaaagaaa tccccttgcg ctctttgggc
     1501 gctctggtga taacgcggcc tttgatacgc tctttgatgg cttcctcggt gtaggcttcc
     1561 cccaatgtct tgcagcgggt aaagcgttcc tgtccgggag cgcggaaaga aataaacttt
     1621 cccggcttga tctcatagcc ctgcgcctgc atgagccgca ggaaatcatc aaaatctttt
     1681 gcctgcggga tagcggcgtc aatggctgct ttgagcttcg ctttccagct cgtccctttc
     1741 cgctgggcgt cccactcggc atagctcttg cccttactct ggccgggctt caccacggac
     1801 aatccgtttt ccttgcacag cctgtcgctg gtgcgccgga tataggcata gctctgtttg
     1861 ttggaaatgt acttgcgctg atttaccata tccacggcac agaaaataat gtgattgtgg
     1921 acgtggccct tatcaatatg ggtagtcagc acatagggat atttcccttg cagcacttcc
     1981 tcggcaagct gcttcccgat ctcatgggcc tgttccggcg tggcttcgcc gggggcaaag
     2041 gattgtatca ggtggtggcc cagattattg cccttttggt atgcctgcgc cagcagcatt
     2101 tcaaattcaa tgtccgctgt ttcataagag caggcaaagg aggccaccag cagcttgccg
     2161 tcagttttgt ccgggttctc gatgtagtca agggcttttt tcagcgttga cttgatagga
     2221 tgtatctttg taactgccat atctgcgcca gcgccccctt tatatcctcg atgtcctgtg
     2281 cgtacaccgg ccccataccg ttcagcctct ttgcaatctg attgacgttg acgccgatct
     2341 tctgtatctc ggcggtctgc gcccggatgt cgctggtgtc catgttgacg atatagccgt
     2401 caatgagcat cttccgggcg taggctgaaa agttcttcgt atgcagcagc gccattttct
     2461 gttcaatcat agcccgttcc tccggcgtca cagggacgcg cagcacgatt tttcgctttc
     2521 tgtttgccat gcttcaccgt cctttccatt caggggtttg gggatttccc caacaagcaa
     2581 aacggacgcg gcccggcagg gacggggcag gccgtttttc cgggagtggc tacactccct
     2641 atgcttgcta cgttactgtt tctccactaa caagacgttt ccaaagcccc aaactacccg
     2701 caaaatagcc ctctggaaag aaaaaagtgc aaaaaaatag aagctacgct gtgcagctcc
     2761 cgctaaaagt aaaacagagg atgccagtta cacatcctcc gtttcattct tcttcggctt
     2821 ttcaattagt atggcgctgt caatcgcgcc ctcgatgatc ggcaggtatt cttcggggca
     2881 gagtttcagc ttgtggctga ccctttgccg cagttcgctt tcctcccgca tgatctccgg
     2941 gttaaagtag cgttccacag gaagcccgca ggctttaata agctgtatga caaccggcag
     3001 actgggaatg gcccgtcgtt ttcgatgttg gcaagatagc gccagtcaat atttattttc
     3061 tctgccattg ctttgcgcga aacgcgcttt gcttgccggg ccgctttcac atccgcgccg
     3121 aaagtttcaa agccgggaca atcttcaata ttcgccatat cgcacctccc acttacattg
     3181 tatatttcat actctgcccg tggaatgttg gtatatgcac ctttcttaaa gtttatattt
     3241 cacattttgt ttcttttatt cttcgagcaa aagaattata atgtaccctg tggaggtgta
     3301 ctatggacta catgacgttg aaagaggcag gcgagaaatg gggtgtgccc ccacgatgga
     3361 taaactacta ttgtgctgcg ggacgcatcc ccggcgctgt aaagatggcg acgatctggc
     3421 tcattcccaa aactgcggaa aagccgattg acaggcgtac aaagaaagga aaggcggtta
     3481 ctgaatagta taatgaaacc ggcgcatttt ggatatggtt ttgaagagag agaaagcatg
     3541 gtattttgtc acggaaaaac tataagatga tagatggcag gctgctccag accgataaaa
     3601 agtattctca tctgaaacag aaagaaaaga tttacacatg gatgtatgaa gaagcgaaac
     3661 tttatcatga cagaaatgga aaatgcccga aacaaagacg aggaagctgc tgctgtatca
     3721 gccgtatatg gtagaattga aaaggccggc atctggattc tttatggtga agtctccaga
     3781 cattggataa ctgctggtct aatgcgcctt tgagtatggg gtgattgatt ttaataccgg
     3841 ggaggtacgg ctttttgagg aaaatattct gggatttaca tttggcgatt attacatttc
     3901 ctgtaactgc aaggacacgg atgatgaaga tatgaggaat atagacttgc tgattttcta
     3961 ctgtcttgaa cggtattagg actgaatctg ctgcgcggag tgcggcaaga gcgaccggag
     4021 ggagtacaca caggccctgc ctgtgtgaaa agccataccg caaggtgcat tcgcaaaaaa
     4081 gaggccgcgc attttgctga ggcttggggt gtccccaaca agcaaaacga gaacgccgca
     4141 ggcgggcaag tggtggatca gaatatccgt aaaggatatt ctgatccatt gcttgccagt
     4201 attatcggga tgttttgaca accgctgtaa tcgaaacatc ccaaacatta agaaggtgtt
     4261 aattattatt atcttgattt aattcgttta aaccaataat atagatacat acaccatgaa
     4321 aagaagcgag tatcccaatg acggatgatt aaaatccgaa aagaaatcgc tttgaaacta
     4381 cagggaaact acagactgtt atgttatctt cttaaaatgg agggattttt atgtcgatac
     4441 gaattctact tgtcgaggat gatgatcata tctgtaatac agtaagggcg tttctggctg
     4501 aggcaggata tcaggtggat gcctgcacag atggaaatga ggcatacacc aagttttacg
     4561 aaaacactta tcaactggtt attcttgata ttatgctgcc cggtatgaac gggcatgaac
     4621 ttttgcgtga atttcgtgcg aaaaatgata ctcccattct gatgatgaca gccctgtcgg
     4681 atgacgaaaa ccaaatccgg gcgtttgatg cagaggcaga cgactatgta acaaagccat
     4741 tcaagatgca gattttacta aagcgggtgg aagccctgct gcggcgcagc ggtgcgctgg
     4801 caaaggaaat ccgtgtcggc aggctgacac ttctgccgga ggatttcacg gtactttgtg
     4861 acggtacaga gctgcccctg acacgaaaag aatttgaaat ccttttgctg ctggtgcaga
     4921 acaaaggcag aaccttaacg catgaaatca ttttgtcacg tatatgggga tatgactttg
     4981 agggtgatgg cagcacagtc cacactcata tcaaaaattt gcgggccaag ctgccggaaa
     5041 atatcatcaa aaccattcgc ggtgtaggat accgattgga ggaatcataa taatggaaag
     5101 aaaagggatt ttcattaagg ttttttccta tacgatcatt gtcctgctac tgcttgtcgg
     5161 tgtaacagca acactgtttg cacagcaatt tgtgtcttat ttcagagtga tggaattaca
     5221 gcaaacagta aaatcctatc agccattggt ggaactgatt cagaatagcg ataggcttga
     5281 tattcaagag gtggcagggc tgtttcacta caataaccaa tcctttgagt tttatattga
     5341 agataaagag ggaagcgtac tctatgccac accaaatgcc aatacatcaa atagttttag
     5401 acccaacttt ctttatgtgg tacatagaga tgataatatt tcgattgttg ctcaaagcaa
     5461 ggcaggtgtg ggattgcttt atcaagggct gacaattcgg ggaattgtta tgattgcgat
     5521 aatggttgta ttcagccttt tatgcgcgta tatctttgcg cggcaaatga caacgccgat
     5581 caaagcctta gcggacagtg cgaataaaat ggcaaacctg aaagatgtac cgccgccgct
     5641 ggagcgaaag gatgagcttg gcgcactggc tcatgatatg cattccatgt atgtcaggct
     5701 gaaagaaacc atcgcaaggc tggaggatga aatcgcaagg gaacatgagt tggaggaaac
     5761 acagcgatat ttctttgcgg cagcttctca tgagctaaaa acgcccatcg cggctacaag
     5821 cgttctgttg gagggaatgc ttgaaaatat cggtgactac aaagatcatt ctaagtatct
     5881 gcgcgaatgc atcaaaatga tggataggca gggcaaaatc atttccgaaa tactggagct
     5941 tgtcagcctg aatgatggga gaatcgtacc catagctgaa ccgttggaca tagggcgcac
     6001 ggttgccgag ttgctgcccg attttcaaac cttggcagag gcaaacaacc agcggttcgt
     6061 cacagatatt ccagccgggc aaattgtcct gtccgatccg aggctgctcc aaaaggcact
     6121 atccaatgtc atattgaatg cagttcagaa cacgccgcag ggaggcgagg tacggatatg
     6181 gagtgagcct ggtgctgaaa aatgccgcct ttttgttttg aacatgggcg ttcacattga
     6241 tgatactgcg cttccaaggc tgttcacccc attctatcgc attgatcagg cgcgaagcag
     6301 aaaaagtggg cgaagcggtt taggacttgc catcgtacaa aaaacgctgg atgccatgag
     6361 cctccagtat gcgctggaaa acacctcgga tggcgttttg ttctggctgg atttaccgct
     6421 cacatcaaca ttgtaaatat ttaaaactta aatgattttg ggctctttgt caaataggac
     6481 tgatagagtg agataagaac
//
LOCUS       DBBGSZ010000173         4428 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.guided.095, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000173 DBBGSZ010000000
VERSION     DBBGSZ010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4428
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.guided.095"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            192..998
                     /locus_tag="ACIZE5_002986"
     CDS             192..998
                     /locus_tag="ACIZE5_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HGC6110036.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            1016..1696
                     /locus_tag="ACIZE5_002987"
     CDS             1016..1696
                     /locus_tag="ACIZE5_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HGC6110037.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGETF
                     SFWWLVRHADKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGH
                     EVKEFPEPNSDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVFADKEP
                     QALYKITNGSIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPES
                     VDIQEENQ"
     gene            1693..2664
                     /locus_tag="ACIZE5_002988"
     CDS             1693..2664
                     /locus_tag="ACIZE5_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HGC6110038.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVSHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            2657..3685
                     /gene="vanB"
                     /locus_tag="ACIZE5_002989"
     CDS             2657..3685
                     /gene="vanB"
                     /locus_tag="ACIZE5_002989"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HGC6110039.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKAAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            3691..4299
                     /locus_tag="ACIZE5_002990"
     CDS             3691..4299
                     /locus_tag="ACIZE5_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HGC6110040.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
BASE COUNT         1248 a          921 c         1190 g         1069 t
ORIGIN      
        1 tagaatgatt ttctatcagt cctagaaatt atagagccga ttttgaccga caggtataac
       61 cctgccggtc tttttttgct gctacaggaa aactacagac tggctacagg gaaagtacag
      121 atgcgcttgc cataataaca atcgtaccag ccacaaatcg tagttttatt gcaaaggagg
      181 cattcgatca aatggaaaaa agcaactatc attccaatgc ggatcatcac aaacggcata
      241 tgaaacaatc cgtggaaaag cgggcttttc tatgtgcgtt cattatttcg ttcacagtct
      301 gcacgctgtt tttggggtgg agactggctt ccgtattgga ggcaacacag ataccgccca
      361 tccctgcaac tcatacaggc agcagcactg acgtagtgga gaatttggag gaaaacgctc
      421 ttgccaccgc caaagaacag ggagatgaac aggaatggag cctgatttta gtgaacaggc
      481 agaaccccat ccccgcacag tacgatgtgg agcttgagca actatcaaat ggtgagcgga
      541 tagatattcg gatttctccc tatcttcaag atttgtttga tgccgcaaga actgatggag
      601 tttacccgat tgtcgcatcc ggataccgaa caacagaaaa acagcaagaa attatggatg
      661 aaaaaattgc cgaatataag gcgaaaggct acacctctgc acaggctaaa gcggaagcag
      721 aaacttgggt ggccgtgccg ggaacgagcg agcatcagct tggtcttgct gtggatatca
      781 atgcggacgg aattcattca acaggcaacg aggtttatag atggctggat gaaaacagct
      841 atcgttttgg ttttattcgt cgctacccac cagacaagac agagataacc ggtgtgagca
      901 acgagccgtg gcattaccga tatgttggca tcgaagctgc cacagagatg tacaaccaag
      961 gggtttgcct tgaggaatat ttaaaaccag aaaaatgaga aaaggatgtt atgttatgga
     1021 cagaaaaaga ttgacacagc gtttcccgtt cctgcttcca atgagacggg cgcagagaaa
     1081 aatgtgcttt tatgcgggaa tgagatttga cggctgtcgc tatgcgcaga cgatagggga
     1141 aaccttttct ttctggtggc tggtacgcca tgcggacaaa gataccccct ataaagacgg
     1201 ccttacggtg accaatggta aactcaccac catgtcgggc ggcggtatgt gccagatgag
     1261 caatttacta ttttggatgt tcctgcatac gccattgaca attatccagc gcagaggtca
     1321 cgaagtaaag gagtttccag agccaaacag tgacgagatt aaaggggtgg atgcaaccat
     1381 ttcagagggc tggattgatt taaaagtgcg aaacgatacc gactgcacct accaaatatg
     1441 ggtgacctta gatgatgaga aaatcatcgg tcaggtgttc gccgacaaag agccccaagc
     1501 attatacaaa attacaaatg gcagtatcca gtatgtccgt gaaagtggcg ggatttatga
     1561 atatgcccag gttaaacgga tgcaagttgc cttaggtacc ggggaaataa tagattgcaa
     1621 gctgctttat acaaacaaat gcaaaatctg ttatcccctc ccggaaagtg tggatattca
     1681 ggaggagaac caatgagaaa aagtgtgggc attactgttt ttggatgcga acaggatgag
     1741 gcaaatgctt tccgcgcttt atcgccggat tttcatatta tccctacgct gattagcgat
     1801 gcgatatcgg cagacaacgc aaaattggcc gctggcaatc aatgcgttag cgtaagccat
     1861 aagtccgagg tttccgaggc gacaattctt gcgctgagaa aggtcggggt aaaatacatt
     1921 tctacccgca gcatcggctg cgatcacatt gatacgactg ccgccgagag aatgggaatc
     1981 tcggttggca cggttgcgta ttcgccggac agcgttgcgg attatgcttt gatgctgatg
     2041 ctgatggcca tacggggtgc aaaacccacc atgcacgccg tggcgcaaca agatttcaga
     2101 ttggatcgta tccgggggaa agaactgggg gatatgactg tgggagttat tggaaccggc
     2161 catatcgggc aagcggtcgt caaaaggctg cggggatttg gatgccatgt gctggcctat
     2221 gataacagcc gaaaaatgga tgcagattat gtccagcttg atgagcttct aaaaaacagc
     2281 gatattgtta cgctccatgt gccgctttgt gcggataccc gccatctgat cggtcagaag
     2341 caaattggag agatgaagca aggcgcattt ttaatcaaca ccgggcgcgg agcgcttgtc
     2401 gataccgggg cgctggtgga ggcgttggaa agcggaaagc tgggtggtgc ggcactggat
     2461 gtgttggagg gcgaggatca gtttgtttat accgattgct cgcagaaagt gcttgaccat
     2521 ccctttttgt cgcagctttt aaggatgccg aatgtgatca tcacacccca tacggcgtac
     2581 tacactgagc gtgtgctgca ggatactaca gaaaaaacaa tcaggaattg tctcaatttt
     2641 gaaaggagtt tacagcatga atagaataaa agtcgcaatc atcttcggcg gttgctcgga
     2701 ggaacatgat gtgtcggtaa aagccgcaat agaaattgct gcgaacattg atacggaaaa
     2761 attcgatccg cactacatcg gaattacaaa aaacggtgta tggaagctat gcaagaagcc
     2821 atgtacggaa tgggaagccg acagtctccc cgccatactc tccccggata ggaaaacgca
     2881 tgggctgctt gtcatgaaag aaagcgaata cgaaacacgg cgtattgatg tggctttccc
     2941 ggttttgcat ggcaaatgcg gggaggatgg tgcgatacag gggctgtttg tattgtctgg
     3001 tatcccctat gtgggctgtg atattcaaag ctccgcagct tgcatggaca aatcactggc
     3061 ctacattctt acaaaaaatg cgggcatcgc cgttcccgaa tttcaaatga ttgataaagg
     3121 tgacaagccg gaggcgggtg cgcttaccta ccctgtcttt gtgaagccgg cacggtcagg
     3181 ttcgtccttt ggcgtaacca aagtaaacgg tacggaagaa cttaacgctg cgatagaagc
     3241 ggcaggacaa tatgatggaa aaatcttaat tgagcaagcg atttcgggct gtgaggtcgg
     3301 gtgtgcggtc atggggaacg aggatgattt gattgtcggc gaagtggatc aaatccggct
     3361 gagccacggt atcttccgca tccatcagga aaacgagccg gaaaaaggct cagaaaatgc
     3421 gatgattaca gttcccgcag acattccggt cgaggaacga aatcgggtgc aggaaacggc
     3481 aaagaaagta tatcgggtgc ttggatgcag agggcttgcc cgtgttgatc tttttttgca
     3541 ggaggatggc ggcatcgttc taaatgaggt caataccctg cccggtttta catcgtacag
     3601 ccgctaccca cgtatgatgg ccgccgcagg aatcacgctt cctgcactga ttgacagcct
     3661 gattacattg gcgttaaaga ggtgataagt atggaaaatg gttttttgtt tttagatgaa
     3721 atgttgcatg gcgtccgttg ggatgccaag tacgccacat gggataactt cacaggaaaa
     3781 ccggtggatg ggtatgaggt gaatcgcatc atcggcacaa aggccgtggc gtttgctctg
     3841 cgcgaggcac aaatccatgc ggctgcgctt ggctatggct tgcttttatg ggatggatat
     3901 cggccaagaa ctgcggtgga ctgcttcctg cgttgggcag cgcaaccgga ggacaatctc
     3961 acaaaagaaa aattttaccc caatatagag cgagccgagt tgattacaaa gggttatgtg
     4021 gcctcacaat ccagccatag ccgtggaagc gcaattgatc ttacgctcta ccacctggat
     4081 acaggggaac ttgtttcaat gggaagtaac ttcgatttta tggacgaacg gtcgcatcat
     4141 acagcaaaag ggatagggga tgcagaggca caaaatcgaa gatgcttgcg taaaatcatg
     4201 gaaagcagcg gatttcagtc ttatcgcttt gaatggtggc actataagtt gattgatgag
     4261 ccataccccg atacctattt taattttgcc gtttcataat gaaagtattg gttttgtatc
     4321 agattttgga tttgataaaa tctatgctgg tcatggacaa tcttttactg gaaagtggtt
     4381 aaagcatctt ttgtaataca ttgcaaatta tagtattcaa tctgccca
//
LOCUS       DBBGSZ010000174         3957 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.guided.099, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000174 DBBGSZ010000000
VERSION     DBBGSZ010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3957
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.guided.099"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            complement(40..342)
                     /locus_tag="ACIZE5_002991"
                     /pseudo
     CDS             complement(40..342)
                     /locus_tag="ACIZE5_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
     gene            435..784
                     /locus_tag="ACIZE5_002992"
                     /pseudo
     CDS             435..784
                     /locus_tag="ACIZE5_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1056..1346)
                     /locus_tag="ACIZE5_002993"
     CDS             complement(1056..1346)
                     /locus_tag="ACIZE5_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6110041.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1748..1984
                     /locus_tag="ACIZE5_002994"
     CDS             1748..1984
                     /locus_tag="ACIZE5_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6110042.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1991..3943
                     /locus_tag="ACIZE5_002995"
     CDS             1991..3943
                     /locus_tag="ACIZE5_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HGC6110043.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
BASE COUNT         1383 a          668 c          689 g         1217 t
ORIGIN      
        1 tatggatttt ttcatttaca caaaatattt tatactctca acatacttgc aaagtaatac
       61 tacaattcct aacataatcg tagaatttaa taatttccat agcataaagt gtttagaaaa
      121 gaacattaag aatagttcta taataattct tgaactccat gtcttataat gttctatcga
      181 agcacccaaa tagccaagtt catctaatct acttgcataa actacgtcat ccgctctcat
      241 agtcggcata tacatattaa agagtaaaaa gataccccaa atccctatta gtaacaagat
      301 cagttctttg ttattcgtta tttttctatt atgtttgttc atttttatac tccttcttat
      361 atttcctaat agagtataac atagctttaa gcattactta aagataactt aaaagttatc
      421 ttttaaatac ttaattgtta aataccttat ttgatgcaaa agaaatctac gatagtcaac
      481 aaaaaaattt tcattatatc cagaaaaatt tttcttagtt aaggacctat ggattgcagt
      541 aatgcagaat tcgtcgaata aactgccaaa gacatacaat catattgctt ttaaaattga
      601 cgaacaagat atagattcgt ttgtctcaaa aatccaaatg ttaggtttaa ctgtcgaacc
      661 aggacgttct cgtgtgaaag gcgaggcttc ttcaatttac ttttacgact atgataatca
      721 cctcttcgag ttacataccg gtactctcca ggaacgttta aaatcctaca attccactac
      781 ctgagactag taatgactag tctcttttta tggcctctga tccccccatt gagcgaatac
      841 taatagggct tcgaattgat ctgttcaatc tttaagcaat atccctcaaa tgagtttgga
      901 aagtttagtg attcatcaca aatacttaaa tacatgtagt tatatataga ttgaggttct
      961 tgtgagcgta tgctcgtgtg ggttcaaatc ccatcgtctg catccatctt tccaaaacaa
     1021 gcggctagga catttttgtc tcagccgctt gttttctagt ttattctttc atcttgtcgg
     1081 accttttttc ttgggtatag acttttctca tattctacca caattttggg tttccctaac
     1141 acatgatagg atctcacaac aaattgcttt ctattattat aataacctgt aacgactaac
     1201 ttcatccctt cgtctacttc agctaggaag ttcaaactat gggaagcaat caaacaattg
     1261 accccattta aactgaaacg gatcaacggt ctggcactaa cttgcaaagt acggatctta
     1321 tctactgttc catatttttt ctccataacc ttcacctcaa taccattata cgaacataca
     1381 ttccctttgt aaagaagaaa ctctgtttta tctttttgac tttttgtcta ttacctttct
     1441 taaaatcata ttggcacttc ctgcgaagat gaaggacatg tactaaaaaa aagaggcagc
     1501 agtatagatt taagtagttc agttttggag tacaaaaagt gaaaatgtaa acctaaatga
     1561 gtatcaaatt gcaactgaat ttgatactcg ttttttattg ttaaatcaac gtttgttgtt
     1621 aatttacacc acaaaatgta agttaaaatg tatataaaaa tgcgaacgtg aaataattat
     1681 tgtaggaatg caaattggtg tgttaaaatg gttacaattt actaagcaaa aaggggtgca
     1741 ttttcctatg caatttcttg agccaaaaaa taagaacgct aagtctgtgg attgggaaat
     1801 atcagagcaa gtaagggtga tagttaagca atacgctgaa tatgcagagc gtactgaaag
     1861 cgaagcagtg gatgaattct tattgaacat tttagacgat aagaagttta ttgaatggat
     1921 tgccaacaag cgaagtaata agcggattgt tgaaaaaatg ggtatcaaag atagagtggg
     1981 ttgatagaca atgaccaagc ttaaaagatt agccacgaag gaagatgaaa ttgtagatgt
     2041 taaaattccg atttcaaacg aagaattaaa agatagggct aaacaatatg atttattaac
     2101 tccaaaacga tttgcaacaa ggtataacaa aatgttgttc ttgccaacgt cttttaaatg
     2161 gaacggttct gaatatccca ttcaatataa ttactgcatc aatccgtttt gttgtaattt
     2221 tgggaaagaa cagcacaaat tcaaagatgt aaaagggaaa ccaagtcgat ataaaatgac
     2281 tggtagttcc aaagataaag gtcataaagg tatgtactgc aatgacaatc ctattggcag
     2341 aggtgtatcg caaaactgta cagtaacccc tttatctaat tggtctgttg ttgaagaaat
     2401 taaacgcctt atagaaatca atagcatcca agatgttgag ccagattatc aatttcataa
     2461 agaaggctgc tcggaagaag aatcaacccc attcaatgag ccgaagcaat tttacaaaag
     2521 ggggaaaagt aggggcaaat ctcaacgcta tcaatgtaag gcgtgtaaga agttcactaa
     2581 tgttctacca aaaagagaag aaaccactac ttatcaccaa caaaagaaca ccattcttcc
     2641 aatgttcgct aagatggttg ttggaagggt ttcagtcagt cgtacttgtg atattttagg
     2701 aattggagtt ggaacctact atcataagct ggagtggctg tataggcgtt gtttggagtt
     2761 tttagaacga tatgagacac aaccccttca aacaaagaaa tttaacgaga tgtggcttaa
     2821 tacggacaag atgcactact acctaaataa cgtccgtaag aaaggacaag gttcaaagaa
     2881 atatacgggg tttgaagacc ttaatatgca aacgtatata gttgtatctg ctgaggtctt
     2941 atcaagatat gtgttccgtt ctgatgttgc ctatgattgg aatatttcaa tggatgaatt
     3001 aaatgaagat acaagaaaat tcaaagaaga ccatctcaat acttttagtc gtaaaaatga
     3061 taggttagat tggtcttatt atccacaaga accatccgct aacgatagcg aaaataggaa
     3121 tgcttatctt cacgaattag ggaaaattac taataggagt agatttgtcg atggtttaaa
     3181 tgttgatgct ccttatacta caactgctca ctattggtta attaaacaaa tggttaatgc
     3241 cgacgaatgg cgaatgatta gtgatgatga cttctctatt agaaacgcct tttatagagt
     3301 attcacgaaa gaattaaggt tgagcgatgc acatcatttt atttgccaag ttaacaagac
     3361 gaaaagcaga aaacaatgct taaaagaatt cggacaagca aaagcagaac tgctcgattg
     3421 gggagatatc agaggattca aaacaaagtt tctacggact ttggcatctc attatctaac
     3481 tgaattacta acaagtcatc aattccacga agaggctatt agtaaagatg gagaaagata
     3541 tcgcaaatat gccgataacc ctatcaaaca tccattagcc actaaggata aaggatttta
     3601 ttcagttgat tgtagaacgg atttatctgc tctggaacca aacgaaatcg caaagatgct
     3661 attaaatgtt aatgaccatt cgaccaatag ctttattcaa cagataagac gttatatatc
     3721 atctcttgaa agaccattaa caacagctcg tggtgataag aagagctata tttacgctaa
     3781 cttcaatccg aagtatgctc aatttgcgat tacaattcta agaacttact acaacttttg
     3841 tcgccctttt aaatcagcgg ataaaaaggt tttgacacct gctcaaagat tagggattac
     3901 agataaacaa tttgattgga aagatataat ttatttcaaa tgacaaaaag agcttgg
//
LOCUS       DBBGSZ010000175         2669 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.guided.107, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000175 DBBGSZ010000000
VERSION     DBBGSZ010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2669
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.guided.107"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            216..953
                     /gene="erm(B)"
                     /locus_tag="ACIZE5_002996"
     CDS             216..953
                     /gene="erm(B)"
                     /locus_tag="ACIZE5_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HGC6110044.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1216..2079)
                     /locus_tag="ACIZE5_002997"
     CDS             complement(1216..2079)
                     /locus_tag="ACIZE5_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HGC6110045.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2081..2353)
                     /locus_tag="ACIZE5_002998"
     CDS             complement(2081..2353)
                     /locus_tag="ACIZE5_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HGC6110046.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2370..2579)
                     /locus_tag="ACIZE5_002999"
     CDS             complement(2370..2579)
                     /locus_tag="ACIZE5_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HGC6110047.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
BASE COUNT          810 a          483 c          421 g          955 t
ORIGIN      
        1 accttatttg atagtagatt taaaactttg caacagaacc acatctaccg ttttgaaaca
       61 gactaaaaac agtgattacg cagataaata aatacgttag attaattcct accagtgact
      121 aatcttatga ctttttaaac agataactaa aattacaaac aaatcgttta acttctgtat
      181 ttatttatag atgtaatcac ttcaggagtg attacatgaa caaaaatata aaatattctc
      241 aaaacttttt aacgagtgaa aaagtactca accaaataat aaaacaattg aatttaaaag
      301 aaaccgatac cgtttacgaa attggaacag gtaaagggca tttaacgacg aaactggcta
      361 aaataagtaa acaggtaacg tctattgaat tagacagtca tctattcaac ttatcgtcag
      421 aaaaattaaa actgaacact cgtgtcactt taattcacca agatattcta cagtttcaat
      481 tccctaacaa acagaggtat aaaattgttg ggaatattcc ttaccattta agcacacaaa
      541 ttattaaaaa agtggttttt gaaagccatg cgtctgacat ctatctgatt gttgaagaag
      601 gattctacaa gcgtaccttg gatattcacc gaacactagg gttgctcttg cacactcaag
      661 tctcgattca gcaattgctt aagctgccag cggaatgctt tcatcctaaa ccaaaagtaa
      721 acagtgtctt aataaaactt acccgccata ccacagatgt tccagataaa tattggaagc
      781 tatatacgta ctttgtttca aaatgggtca atcgagaata tcgtcaactg tttactaaaa
      841 atcagtttca tcaagcaatg aaacacgcca aagtaaacaa tttaagtacc gttacttatg
      901 agcaagtatt gtctattttt aatagttatc tattatttaa cgggaggaaa taattctatg
      961 agtcgctttt gtaaatttgg aaagttacac gttactaaag ggaatgtaga taaattatta
     1021 ggtatagggc acctctaata actaccaatt aattcacctc aaaatgaaat tagaaaaaaa
     1081 cagcgaaatt tttaaatcta tttcttatcg atacaaattc ctcgtaggcg ctcgggaccc
     1141 caacatgagg aaatgttttt ataaaaaaag agtagttacc gttttttggt aactactctt
     1201 ttcctttttt aaggtttaaa tacctggaag tttaggtgtt ttgggtattg gtggtgtagg
     1261 tagctgcaag ctttccattt tttgttgaat tgctttaaat tcaggggttt cttggtgttg
     1321 attttgaacc attttttgct ctattctctc caaagtcggt tgaatttctt tccctgatac
     1381 tttacgattt aattctcttt ctaaggtctc tttcggacta atggaaggcg tttctaagct
     1441 tgaatagagt ttcactcctt ctctattgta aagccttata tcgctaaata agcccgtttt
     1501 atgaagggtt tctaaattgg tcggtaagtt tttgacaaca atatcatgcg cttgttttgg
     1561 tgttgcccta gctgtcattg gatcatctgc atacatggtt tcatatcgtt caatcgttcc
     1621 taagtatgat tcaattttcg gtactgccat gacgtatatt tttgtttcat aacctttaga
     1681 ttgaagcatt gtggctgttt gaatgggaac gtctgttgtt cgtcctgttc cttcaatcac
     1741 taaattatag ccttgatcgc ttaaacggct aataagtgct tctgtcatgc gattcgaata
     1801 aggggtaacg tgttttacta cgtctttttc atagagtttc actaattcgt caaaatttgg
     1861 gtgctgttgt ttaaaggtat cattatcaat gacaataaca ttcccttgtg tttcttcaaa
     1921 aattgctgat cgcaaactgg ttttccctga ccctggttgc ccaccaagta aaaaagcggt
     1981 tggcgattca accgctagtc tatttttagt tagtcgttca acattctttt ctaaacgatc
     2041 ttcaaattgc ttttcggtga agtcagtaat attcgccatg ttaagccact ttctctttat
     2101 tcaaaatttg ttttgaatat tgattcattg accgccaata ctcatgaata gcttgtaatt
     2161 cttcaaatgg ttgttgaaat aaatcaactt cttgtgccac ttctaattga tttaaaagat
     2221 tcacttctag taaacgagta tttttagtat ctagttcatg attcaaaaca taatttaata
     2281 cccgattata aacacttgcc gataactcat taatgatttc aatttcaaat gttttttcat
     2341 acgtaactgc catttcattt tcactccttt taaagtttgt caggtaaata tttccgtata
     2401 tattcttcta aggcttgatc cataacttct tttacgtttc cgccattctt tgctgtttcg
     2461 atttttatga tatggtgcaa gtcggcacga acacgaaccg tcttatcccc cattatatct
     2521 ttttttgcgc tgattggcgt atcatttcgt tttgctttct gtgcgcctaa atttcccacg
     2581 atcgctcact tctttctatt tcttcttact atttatttta tcatcaccta tcacaaatca
     2641 caagtgattt gtgattaatc acttgtgat
//
LOCUS       DBBGSZ010000176         1935 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345622-rid23690253.guided.114, whole genome shotgun
            sequence.
ACCESSION   DBBGSZ010000176 DBBGSZ010000000
VERSION     DBBGSZ010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345622
            Sequence Read Archive: ERR12710961
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429586.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429586.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:14:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,001
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,857
            CDSs (with protein)               :: 2,857
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 36 of 78
            Pseudo Genes (incomplete)         :: 39 of 78
            Pseudo Genes (internal stop)      :: 25 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1935
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345622-rid23690253.guided.114"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-12"
     gene            322..1014
                     /locus_tag="ACIZE5_003000"
     CDS             322..1014
                     /locus_tag="ACIZE5_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGC6110048.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            1341..1838
                     /gene="dfrG"
                     /locus_tag="ACIZE5_003001"
     CDS             1341..1838
                     /gene="dfrG"
                     /locus_tag="ACIZE5_003001"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HGC6110049.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
BASE COUNT          792 a          244 c          345 g          554 t
ORIGIN      
        1 tttcataggt aaaagaagca tgacaattta tgacaaatcc gcgttttttg taataaatac
       61 agtaatctat gaaatgaaaa gggttacgtt taataaaact tgcttttttg tttttgttca
      121 ccataaatat ttatttaaga aagtattaac ctgcattttt ctctataaaa aagatttttt
      181 aaatagataa aaaaggagga ttaaatgagt atttgatagt atttatatta aaattacata
      241 tgtaatttaa aaacgcttga cattgtgttt gagatcactt acttttagca tgtaaaagta
      301 ttggattaag gagctatgca aatgaaaaag aaatttatta ctggtgggat tgtcgttgca
      361 tttctatgtc taattggcta cacaggcacg cggtacgcaa atgaaattat tttgtggggt
      421 ggagagacag atattgatac aatcaatgag aatctgacac agcttgatca tacattgaca
      481 gataaagagc aagcgattac agatcttacc gctcgactag cacaaaaaga acagacattg
      541 caagattcaa aggcagatgt ccaagaatac caaacaaaag taaatgaatt agaaaaccaa
      601 aaaaatcaat cggcagcaga aaaacaaaac ttagaaagtc aattagtcag caaggatgca
      661 caactacaaa gcaaacaaaa tgaaatcaat gtcaaactag atgagatcaa ccaaaaaaat
      721 gatgaaatca atcatctgaa tgcagattgg acagcaagac tacaagaagc acaagcaaaa
      781 ctttcagaat tacaaaatac tgtaaatggt ttgaatcaac aaatcgcaac actgacacaa
      841 gaaaaaacaa atgtagaaac tcagttaaca gatacacaaa agaaattaga cgaagcaact
      901 gctgaaaact caagcttgaa acaatatatt caaaagttag aaaaagcaaa agatgaagtg
      961 gaagatacag ctgataaatc tcagcaaatt gttgaagaac atttgcgtaa ataatctttc
     1021 ttaacaagta aacctaaatt agtaaagaag caacagtaat ctatactaag tagttcagtt
     1081 ttggagtaca aaatgacaaa atgtacttca aaatggacta cttttttcat tttaacttac
     1141 ataccaaatt acatacaaaa tgatttataa aatgcaattg aaaatgataa ttgaatgaaa
     1201 atttgtgatt ttgtggtatt atgataatat aacttataga aaaaattgct tattcaacta
     1261 acgggcagga taatgagaaa aggttttttg atagaaataa gaaattagat ggtaaattag
     1321 ttaaaaaggc tgtgttataa atgaaagttt ctttgattgc tgcgatggat aagaatagag
     1381 tgattggcaa agagaatgac attccttgga ggattcccaa ggactgggaa tatgttaaaa
     1441 atactacaaa gggacatccg ataatattag gtaggaagaa ccttgaatca atcggaagag
     1501 ccttacctga cagaagaaat attattctga cgagagataa ggggtttacc tttaatggtt
     1561 gtgaaattgt tcattcaata gaagatgttt ttgagttatg taaaaacgaa gaagaaattt
     1621 ttattttcgg aggagaacag atttataatt tgtttttccc ttatgttgag aaaatgtaca
     1681 tcacaaaaat acatcatgaa ttcgaaggag atactttttt tccagaagtg aattatgagg
     1741 aatggaatga ggtatttgcc caaaaaggga taaagaatga taaaaatccg tataactact
     1801 attttcatgt atatgaaaga aaaaacttat tgagttaacg ggtgcgttaa ttgaagaaga
     1861 acagtaaaga taaagcacaa gagcttggga ttactccaag ctctttttgt catttgaaat
     1921 aaattatatc tttcc
//
